# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RNase_P_p30 PF01876.11 KFX85687.1 - 2.9e-45 153.1 0.0 3.9e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 TFIIS_M PF07500.9 KFX85689.1 - 5.5e-27 94.1 1.8 7.6e-27 93.6 0.2 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFX85689.1 - 3.3e-18 65.0 6.0 5.3e-18 64.3 4.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KFX85689.1 - 2.1e-13 49.5 0.2 5.3e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med16 PF11635.3 KFX85689.1 - 0.079 10.9 1.2 0.099 10.5 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 PALP PF00291.20 KFX85690.1 - 2.3e-55 187.9 0.7 2.8e-55 187.7 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 KFX85691.1 - 7.9e-38 130.2 0.0 1.4e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KFX85691.1 - 0.0008 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase GrpB PF04229.9 KFX85692.1 - 1.1e-37 129.3 0.1 1.3e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 GrpB protein tRNA-synt_2c PF01411.14 KFX85693.1 - 2.1e-205 683.2 1.0 2.1e-205 683.2 0.7 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFX85693.1 - 2.1e-17 62.7 0.3 4.5e-17 61.6 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFX85693.1 - 6.6e-05 22.5 2.7 8.1e-05 22.2 0.7 2.2 2 0 0 2 2 2 1 DHHA1 domain Dimeth_Pyl PF09505.5 KFX85693.1 - 0.087 11.0 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) XPC-binding PF09280.6 KFX85693.1 - 0.096 12.1 0.3 0.23 10.9 0.2 1.7 1 0 0 1 1 1 0 XPC-binding domain Vps8 PF12816.2 KFX85695.1 - 2.5e-68 229.1 0.0 5.9e-68 227.9 0.0 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KFX85695.1 - 2.7e-06 27.0 0.5 0.062 12.8 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 KFX85695.1 - 0.0089 15.8 0.3 0.022 14.5 0.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX85695.1 - 0.019 15.0 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX85695.1 - 0.15 11.7 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Apc4_WD40 PF12894.2 KFX85700.1 - 1.1e-14 53.6 0.0 5.8e-13 48.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KFX85700.1 - 2.4e-07 30.3 0.0 0.16 11.8 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 KFX85700.1 - 0.004 15.0 0.0 0.0055 14.5 0.0 1.2 1 0 0 1 1 1 1 IKI3 family N_Asn_amidohyd PF14736.1 KFX85700.1 - 0.053 12.3 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Adap_comp_sub PF00928.16 KFX85701.1 - 2e-18 66.4 0.5 2.9e-18 65.9 0.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFX85701.1 - 1.5e-08 34.4 0.1 2.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 KFX85701.1 - 0.0092 16.1 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF4654 PF15547.1 KFX85701.1 - 0.46 10.8 2.8 0.91 9.8 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) DUF2420 PF10336.4 KFX85702.1 - 2.9e-11 42.9 0.0 5.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 KFX85703.1 - 3.6e-112 374.2 14.0 4.2e-112 374.0 9.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFX85703.1 - 1.3e-06 28.5 5.8 1.3e-06 28.5 4.0 3.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KFX85703.1 - 0.00035 20.6 6.7 0.00035 20.6 4.6 3.2 2 2 0 2 2 2 1 EamA-like transporter family Ribosomal_S3_C PF00189.15 KFX85704.1 - 1.2e-16 60.6 0.1 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KFX85704.1 - 2.6e-12 46.1 0.1 4.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KFX85704.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 KFX85705.1 - 7e-125 416.4 0.0 8.9e-125 416.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DUF2531 PF10748.4 KFX85705.1 - 0.013 14.7 0.1 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) Y_phosphatase3 PF13350.1 KFX85705.1 - 0.038 14.2 0.1 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family B3_4 PF03483.12 KFX85706.1 - 5.5e-26 91.0 0.0 9.2e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFX85706.1 - 4.7e-18 64.7 0.0 8.8e-14 51.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 KFX85706.1 - 0.0095 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein HEAT PF02985.17 KFX85707.1 - 7.9e-42 137.5 20.9 0.0015 18.4 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 KFX85707.1 - 4.8e-32 110.1 4.2 3.9e-09 36.6 0.0 7.8 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KFX85707.1 - 1.6e-12 47.6 3.6 0.0045 17.3 0.1 7.6 4 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFX85707.1 - 9.1e-11 41.9 10.0 0.082 13.4 0.1 8.9 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KFX85707.1 - 2e-08 33.0 6.5 5.9e-05 21.5 1.5 3.7 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 KFX85707.1 - 6.5e-05 22.3 3.8 2.7 7.2 0.0 4.6 2 2 1 4 4 4 3 CLASP N terminal DUF2435 PF10363.4 KFX85707.1 - 0.0015 18.3 4.3 1.7 8.5 0.1 4.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KFX85707.1 - 0.018 14.0 1.4 0.14 11.1 0.2 2.6 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KFX85707.1 - 0.054 13.3 4.4 2.4 8.1 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MadL PF03817.8 KFX85707.1 - 0.07 12.9 0.1 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Malonate transporter MadL subunit Cnd1 PF12717.2 KFX85707.1 - 0.24 11.2 10.1 12 5.6 0.2 6.2 3 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KFX85707.1 - 0.24 9.6 4.5 0.64 8.2 0.1 2.7 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Imm25 PF15571.1 KFX85707.1 - 0.25 11.4 3.4 1.3 9.1 0.0 3.4 3 1 1 4 4 4 0 Immunity protein 25 Ank_2 PF12796.2 KFX85709.1 - 3.6e-64 213.1 23.6 7.3e-19 67.9 1.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX85709.1 - 2.1e-46 153.4 20.9 3.7e-09 35.9 0.4 8.4 8 1 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KFX85709.1 - 2.7e-34 116.9 6.1 2.6e-08 34.1 0.1 6.8 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX85709.1 - 2.7e-33 110.6 9.8 8.6e-06 25.5 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KFX85709.1 - 1.7e-21 75.7 12.5 3.5e-05 23.9 0.1 7.2 1 1 7 8 8 8 5 Ankyrin repeats (many copies) FAD_binding_2 PF00890.19 KFX85709.1 - 0.0087 14.9 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1843 PF08898.5 KFX85709.1 - 0.031 14.3 7.1 3.8 7.6 0.0 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF1843) EF-hand_1 PF00036.27 KFX85710.1 - 8.7e-05 21.5 0.1 0.00019 20.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX85710.1 - 0.0025 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KFX85710.1 - 0.0039 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KFX85710.1 - 0.015 14.9 0.5 0.043 13.4 0.4 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 KFX85710.1 - 0.019 14.2 0.1 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 EF hand Adeno_VII PF03228.9 KFX85710.1 - 0.044 14.3 2.3 0.089 13.3 1.6 1.5 1 0 0 1 1 1 0 Adenoviral core protein VII SWIRM PF04433.12 KFX85711.1 - 2.9e-11 43.3 0.0 5.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Syndecan PF01034.15 KFX85712.1 - 0.026 14.1 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 KFX85712.1 - 0.085 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Herpes_gE PF02480.11 KFX85712.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KFX85712.1 - 5.2 6.4 10.9 0.069 12.4 2.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ATP_bind_3 PF01171.15 KFX85717.1 - 9.4e-50 168.6 0.0 2.5e-49 167.2 0.0 1.7 1 1 0 1 1 1 1 PP-loop family Aurora-A_bind PF09041.5 KFX85717.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Aurora-A binding Asn_synthase PF00733.16 KFX85717.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF2419 PF10343.4 KFX85718.1 - 9.5e-132 438.5 1.3 1.1e-131 438.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Spore_YhaL PF14147.1 KFX85718.1 - 0.0074 15.7 0.1 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Sporulation protein YhaL ThiF PF00899.16 KFX85719.1 - 1.1e-40 138.5 0.1 2.6e-40 137.3 0.1 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KFX85719.1 - 1.3e-29 101.5 0.5 3.9e-29 100.0 0.4 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KFX85719.1 - 1.4e-22 79.6 1.2 1.4e-22 79.6 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KFX85719.1 - 1.3e-18 66.0 4.8 2.3e-18 65.2 0.4 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KFX85719.1 - 0.00069 19.8 1.0 0.0024 18.1 0.0 2.4 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KFX85719.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFX85719.1 - 0.076 13.4 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 KFX85720.1 - 1.6e-32 112.7 1.8 2e-32 112.4 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX85720.1 - 1.2e-27 97.3 0.1 1.4e-27 96.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX85720.1 - 2.9e-14 53.1 1.4 4.2e-14 52.6 1.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX85720.1 - 1.2e-07 31.4 0.2 3.8e-06 26.5 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX85720.1 - 6.3e-07 29.5 0.2 8.9e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX85720.1 - 5.2e-05 22.2 0.1 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 KFX85720.1 - 0.00036 20.2 0.1 0.00093 18.8 0.0 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 KFX85720.1 - 0.0021 17.5 0.2 0.0042 16.5 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 KFX85720.1 - 0.0036 16.2 0.1 0.0052 15.7 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein Eno-Rase_NADH_b PF12242.3 KFX85720.1 - 0.0058 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KFX85720.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX85720.1 - 0.059 13.3 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 KFX85720.1 - 0.061 12.4 0.1 2.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Skp1_POZ PF03931.10 KFX85721.1 - 6.9e-09 35.6 0.0 9.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.8 KFX85722.1 - 5.5e-46 156.0 0.0 9.3e-46 155.3 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KFX85722.1 - 2.8e-08 33.4 0.5 4.5e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.6 KFX85722.1 - 7.4 7.1 29.3 16 6.0 20.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family zf-ZPR1 PF03367.8 KFX85723.1 - 2.1e-101 335.8 0.2 4.7e-52 175.3 0.0 2.5 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Rpr2 PF04032.11 KFX85723.1 - 2e-08 33.9 2.8 2e-08 33.9 2.0 2.0 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 KFX85723.1 - 0.0015 18.1 0.0 0.0015 18.1 0.0 3.5 5 0 0 5 5 5 1 Nudix N-terminal Elf1 PF05129.8 KFX85723.1 - 7.5 6.3 13.3 8.9 6.0 0.2 3.7 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like WD40 PF00400.27 KFX85728.1 - 1.7e-48 160.8 22.2 9e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFX85728.1 - 0.0001 22.0 0.0 0.048 13.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Atg14 PF10186.4 KFX85728.1 - 1.6 7.6 4.4 2.5 6.9 3.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ran_BP1 PF00638.13 KFX85729.1 - 1.5e-48 163.8 2.2 3.4e-48 162.7 1.5 1.6 1 0 0 1 1 1 1 RanBP1 domain A_deaminase PF00962.17 KFX85729.1 - 1.3e-34 119.6 0.0 2.4e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase WH1 PF00568.18 KFX85729.1 - 0.0017 18.0 0.4 0.0075 15.9 0.3 2.0 1 1 0 1 1 1 1 WH1 domain YEATS PF03366.11 KFX85730.1 - 1.2e-21 76.1 0.0 2.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 YEATS family DUF3083 PF11281.3 KFX85730.1 - 0.0095 15.0 0.0 0.018 14.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3083) REV PF00424.13 KFX85730.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF4604 PF15377.1 KFX85731.1 - 2.4e-19 70.0 15.3 2.8e-19 69.8 10.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) NYAP_N PF15439.1 KFX85731.1 - 0.024 13.8 0.4 0.024 13.8 0.3 2.0 1 1 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Glyco_transf_15 PF01793.11 KFX85732.1 - 1.9e-133 444.5 0.9 2.4e-133 444.1 0.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UDPGP PF01704.13 KFX85732.1 - 0.016 13.7 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase Peptidase_C2 PF00648.16 KFX85734.1 - 1.4e-24 86.6 0.0 2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KFX85734.1 - 3.2e-06 26.9 3.8 5.4e-06 26.1 2.6 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3770 PF12603.3 KFX85734.1 - 0.14 11.2 0.2 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) SAM_2 PF07647.12 KFX85735.1 - 4e-11 42.5 0.1 7.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFX85735.1 - 3.5e-06 27.0 0.1 7.3e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KFX85735.1 - 0.088 12.7 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif TPR_11 PF13414.1 KFX85736.1 - 7.5e-20 70.3 32.7 5.8e-08 32.2 2.0 8.6 7 3 2 9 9 9 6 TPR repeat TPR_19 PF14559.1 KFX85736.1 - 3.1e-17 62.6 14.2 0.00012 22.3 0.2 7.9 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFX85736.1 - 3.4e-12 46.6 28.1 0.006 17.2 0.0 7.9 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFX85736.1 - 7.8e-12 44.0 20.6 0.0013 18.3 0.1 8.1 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX85736.1 - 1.1e-11 43.9 1.6 0.013 15.6 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX85736.1 - 2.9e-11 43.1 33.8 0.00012 21.9 2.3 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX85736.1 - 5.1e-11 42.1 21.1 0.0022 18.4 0.0 10.2 7 2 4 12 12 11 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFX85736.1 - 1.2e-06 27.8 37.9 5.1e-05 22.7 0.2 10.7 12 0 0 12 12 12 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFX85736.1 - 7.6e-06 26.2 1.5 0.22 11.7 0.0 3.6 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_2 PF07719.12 KFX85736.1 - 1.1e-05 24.9 39.7 0.0014 18.3 0.1 12.3 14 0 0 14 14 14 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX85736.1 - 0.00051 20.1 30.8 0.0015 18.6 3.0 6.4 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFX85736.1 - 0.00093 19.5 19.8 0.25 11.9 0.1 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFX85736.1 - 0.0019 18.2 18.6 0.065 13.3 1.4 5.8 6 2 1 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX85736.1 - 0.0021 17.7 22.8 0.052 13.3 0.1 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF2098 PF09871.4 KFX85736.1 - 2.8 7.9 7.5 0.53 10.2 0.6 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Sec23_trunk PF04811.10 KFX85737.1 - 1.3e-80 270.2 0.0 1.8e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFX85737.1 - 1.1e-33 114.6 0.2 2.9e-33 113.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFX85737.1 - 7.4e-31 106.5 0.3 1.8e-30 105.2 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFX85737.1 - 2.2e-16 59.1 5.9 4.6e-16 58.0 4.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFX85737.1 - 3e-13 49.2 0.0 8.2e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Ribosomal_L22 PF00237.14 KFX85738.1 - 9.7e-35 118.6 0.1 1.3e-34 118.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Sugar_tr PF00083.19 KFX85742.1 - 2.7e-29 102.0 31.3 3.3e-28 98.4 21.7 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX85742.1 - 2.8e-29 101.9 36.0 4.9e-24 84.7 11.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Dicty_REP PF05086.7 KFX85743.1 - 1.1 6.9 8.2 1.3 6.7 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KFX85743.1 - 4.2 7.1 30.4 0.21 11.3 12.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LVIVD PF08309.6 KFX85744.1 - 1 8.4 3.6 2.7 7.0 0.5 2.3 2 0 0 2 2 2 0 LVIVD repeat Fic PF02661.13 KFX85745.1 - 4.1e-21 75.4 0.0 1.2e-20 73.9 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family DSPc PF00782.15 KFX85746.1 - 3.9e-20 71.7 0.0 4.9e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX85746.1 - 0.0013 18.1 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MFS_1 PF07690.11 KFX85747.1 - 5.8e-32 110.7 26.9 8.4e-32 110.2 18.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3425 PF11905.3 KFX85747.1 - 1.1e-30 106.3 1.7 2.1e-30 105.4 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 KFX85748.1 - 2.6e-19 69.7 0.0 4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX85748.1 - 5.4e-08 32.9 0.0 1.6e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX85748.1 - 0.00039 19.9 0.0 0.00068 19.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFX85748.1 - 0.00064 19.4 0.1 0.0016 18.1 0.0 1.5 1 1 0 1 1 1 1 KR domain Pap_E4 PF02711.9 KFX85750.1 - 0.66 10.8 5.0 1.9 9.3 0.1 2.1 1 1 0 2 2 2 0 E4 protein AIM24 PF01987.12 KFX85753.1 - 7.8e-52 175.8 1.0 9.3e-52 175.5 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PSII_BNR PF14870.1 KFX85753.1 - 0.066 12.2 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Med1 PF10744.4 KFX85756.1 - 6.7e-44 150.2 0.0 1.1e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 FAD_binding_3 PF01494.14 KFX85761.1 - 1.9e-06 27.1 0.0 7e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain bZIP_1 PF00170.16 KFX85762.1 - 0.00012 21.9 7.6 0.00019 21.3 5.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX85762.1 - 0.0067 16.2 8.1 0.011 15.5 5.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper DUF3824 PF12868.2 KFX85762.1 - 0.5 11.3 12.8 0.86 10.5 8.9 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) MARVEL PF01284.18 KFX85766.1 - 0.01 15.6 13.5 0.022 14.5 9.4 1.5 1 1 1 2 2 2 0 Membrane-associating domain DUF998 PF06197.8 KFX85766.1 - 0.26 10.5 11.1 0.49 9.6 7.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF998) FA_desaturase PF00487.19 KFX85766.1 - 3 7.1 7.1 3.9 6.8 4.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Coatomer_WDAD PF04053.9 KFX85767.1 - 6.2e-149 496.5 0.0 1e-148 495.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFX85767.1 - 4.9e-76 255.9 0.0 7.3e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KFX85767.1 - 3.2e-49 163.1 12.1 7.7e-09 35.0 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KFX85767.1 - 0.0058 16.3 0.3 2.3 7.8 0.0 3.7 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX85767.1 - 0.007 14.5 7.5 0.46 8.5 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 KFX85767.1 - 0.02 14.4 2.6 0.048 13.2 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS UDP-g_GGTase PF06427.6 KFX85768.1 - 3.7e-64 215.9 0.1 9.8e-64 214.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFX85768.1 - 8e-06 25.3 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 KFX85769.1 - 1e-26 92.4 0.4 4e-24 84.1 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein DUF677 PF05055.7 KFX85769.1 - 0.17 10.4 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF1388 PF07142.7 KFX85771.1 - 0.086 12.5 2.1 0.12 12.1 1.5 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Abhydrolase_6 PF12697.2 KFX85772.1 - 2.5e-22 79.8 0.0 2.9e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX85772.1 - 4.6e-16 59.0 0.0 5.5e-10 39.1 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX85772.1 - 6.1e-10 39.0 0.0 1.4e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFX85772.1 - 0.00054 18.5 0.0 0.0022 16.5 0.0 2.1 1 1 0 1 1 1 1 Ndr family DLH PF01738.13 KFX85772.1 - 0.034 13.4 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KFX85772.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KFX85772.1 - 0.067 12.6 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Caps_synth PF05704.7 KFX85773.1 - 3.3e-12 46.1 0.0 6.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KFX85773.1 - 7.2e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NmrA PF05368.8 KFX85774.1 - 3.8e-27 95.0 0.0 5.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX85774.1 - 0.0036 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX85774.1 - 0.033 12.8 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PAGK PF15284.1 KFX85775.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage-encoded virulence factor tRNA-synt_1c PF00749.16 KFX85776.1 - 2.4e-68 230.1 0.0 1.1e-41 142.5 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain Pkinase PF00069.20 KFX85776.1 - 5.8e-31 107.5 0.0 1.1e-30 106.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain tRNA-synt_1c_C PF03950.13 KFX85776.1 - 1.6e-28 99.5 0.0 6.7e-28 97.5 0.0 2.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Pkinase_Tyr PF07714.12 KFX85776.1 - 8.1e-06 25.0 0.0 0.034 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase SNF2_N PF00176.18 KFX85778.1 - 3.1e-58 196.9 0.0 5.9e-58 196.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KFX85778.1 - 6.1e-09 35.5 7.9 1.4e-08 34.4 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX85778.1 - 4.3e-08 32.6 4.8 4.3e-08 32.6 3.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX85778.1 - 1.4e-06 28.2 8.4 3.4e-06 26.9 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX85778.1 - 2.9e-06 26.9 7.1 7.8e-06 25.5 4.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX85778.1 - 3.6e-06 26.5 7.0 3.6e-06 26.5 4.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX85778.1 - 6.4e-05 22.9 3.9 0.00015 21.8 1.7 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger NPV_P10 PF05531.7 KFX85778.1 - 0.063 13.5 1.8 6.3 7.1 0.1 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_4 PF15227.1 KFX85778.1 - 0.12 12.2 7.8 0.26 11.2 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX85778.1 - 0.23 11.2 4.4 0.73 9.6 3.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KFX85778.1 - 0.24 10.9 3.4 0.54 9.8 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFX85778.1 - 0.58 9.7 6.4 1.9 8.1 4.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KFX85778.1 - 0.65 9.5 8.8 0.12 11.8 3.2 1.9 2 0 0 2 2 2 0 P-11 zinc finger DZR PF12773.2 KFX85778.1 - 4 7.3 5.1 36 4.2 2.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Sec10 PF07393.6 KFX85779.1 - 2.2e-163 545.1 0.0 2.8e-163 544.8 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KFX85779.1 - 1.8e-07 30.7 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX85779.1 - 4.5e-06 26.1 0.0 8.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain RhoGAP PF00620.22 KFX85780.1 - 9.4e-16 57.7 1.6 1.6e-15 57.0 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KFX85780.1 - 2.9e-14 52.9 0.0 2.7e-13 49.9 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KFX85780.1 - 1.4e-11 43.9 0.0 3.3e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 KFX85780.1 - 0.025 14.4 0.0 0.61 9.9 0.0 2.8 2 0 0 2 2 2 0 KIP1-like protein HR1 PF02185.11 KFX85780.1 - 0.056 13.1 0.4 0.21 11.3 0.3 2.0 1 0 0 1 1 1 0 Hr1 repeat DUF2867 PF11066.3 KFX85785.1 - 2e-34 118.4 0.2 1.8e-33 115.3 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2867) Lipase_GDSL_2 PF13472.1 KFX85786.1 - 5.9e-22 78.6 0.0 7.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX85786.1 - 6.8e-17 62.0 0.0 9.8e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 KFX85787.1 - 1.3e-30 106.3 30.3 2.6e-29 102.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KFX85789.1 - 2.7e-45 154.7 0.0 7.2e-45 153.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L44 PF00935.14 KFX85790.1 - 4.7e-35 119.4 11.7 1.1e-34 118.2 8.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L44 DUF2652 PF10851.3 KFX85790.1 - 2 8.4 5.2 0.43 10.5 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2652) TRP PF06011.7 KFX85796.1 - 2.9e-86 289.7 28.0 7.6e-85 285.0 19.5 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFX85796.1 - 5.4e-23 81.5 0.2 8.2e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.6 KFX85796.1 - 4.9 5.3 4.7 7.6 4.7 3.3 1.2 1 0 0 1 1 1 0 Strabismus protein NAD_binding_4 PF07993.7 KFX85799.1 - 2e-31 108.7 0.0 5.3e-28 97.6 0.0 2.8 3 0 0 3 3 3 2 Male sterility protein NmrA PF05368.8 KFX85799.1 - 2.5e-26 92.3 0.4 1.8e-25 89.5 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family AMP-binding PF00501.23 KFX85799.1 - 2.3e-21 75.6 0.0 4.9e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_10 PF13460.1 KFX85799.1 - 1.3e-16 61.1 0.3 2.4e-15 57.0 0.1 2.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KFX85799.1 - 2.3e-13 50.1 0.0 1.4e-08 34.4 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KFX85799.1 - 8e-07 29.2 0.1 3.1e-06 27.3 0.0 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 KFX85799.1 - 0.00011 22.5 0.3 0.37 11.1 0.1 2.7 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX85799.1 - 0.00052 19.9 0.4 0.065 13.1 0.1 2.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KFX85799.1 - 0.00062 18.8 0.4 0.0011 17.9 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KFX85799.1 - 0.0042 15.8 0.2 0.024 13.3 0.1 2.3 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX85799.1 - 0.0085 16.0 1.9 0.26 11.1 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX85799.1 - 0.017 14.8 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 KR domain DAO PF01266.19 KFX85800.1 - 5.6e-48 163.6 0.0 6.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX85800.1 - 3.1e-08 33.5 0.1 6.1e-07 29.3 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFX85800.1 - 1.5e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX85800.1 - 1.6e-05 24.9 0.0 0.00035 20.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX85800.1 - 4.6e-05 22.4 0.0 0.024 13.4 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.1 KFX85800.1 - 0.00029 20.9 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX85800.1 - 0.00033 20.9 0.0 0.00075 19.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFX85800.1 - 0.0015 18.4 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_9 PF13454.1 KFX85800.1 - 0.0023 17.7 0.0 0.059 13.1 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.16 KFX85800.1 - 0.0088 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 ThiF family HI0933_like PF03486.9 KFX85800.1 - 0.011 14.2 0.0 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 KFX85800.1 - 0.011 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KFX85800.1 - 0.018 13.9 0.7 0.18 10.6 0.0 2.2 2 1 1 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.12 KFX85800.1 - 0.021 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KFX85800.1 - 0.056 12.8 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KR PF08659.5 KFX85800.1 - 0.08 12.5 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 KR domain Lycopene_cycl PF05834.7 KFX85800.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.20 KFX85800.1 - 0.099 12.5 0.6 0.24 11.3 0.0 2.0 2 1 0 2 2 2 0 short chain dehydrogenase 3HCDH_N PF02737.13 KFX85800.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyclin_N PF00134.18 KFX85801.1 - 0.0032 17.0 0.0 0.041 13.4 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain COesterase PF00135.23 KFX85802.1 - 2.1e-93 313.8 0.2 2.6e-93 313.5 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX85802.1 - 0.0025 17.4 0.1 0.0056 16.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX85802.1 - 0.05 12.8 0.3 0.08 12.1 0.2 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Zn_clus PF00172.13 KFX85803.1 - 9.1e-08 31.8 12.2 1.9e-07 30.8 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3916 PF13079.1 KFX85803.1 - 0.12 12.0 1.0 0.19 11.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) Fungal_trans PF04082.13 KFX85804.1 - 2.8e-25 88.6 0.4 4.8e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX85805.1 - 5.7e-31 107.5 22.9 7.8e-31 107.0 15.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.17 KFX85806.1 - 3.3e-35 121.0 0.0 3.8e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_hydro_75 PF07335.6 KFX85809.1 - 3e-49 166.8 0.2 3.9e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SRP1_TIP1 PF00660.12 KFX85809.1 - 0.006 16.3 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Seripauperin and TIP1 family Pectate_lyase_3 PF12708.2 KFX85810.1 - 1.7e-41 142.8 24.0 6.4e-32 111.4 8.1 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KFX85810.1 - 0.023 14.1 1.6 0.17 11.3 0.0 2.6 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Sugar_tr PF00083.19 KFX85811.1 - 8.2e-79 265.2 22.4 9.5e-79 265.0 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX85811.1 - 1.1e-28 100.0 16.8 1.1e-28 100.0 11.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX85811.1 - 0.00014 20.4 4.0 0.00014 20.4 2.8 2.7 2 2 0 2 2 2 1 MFS/sugar transport protein UNC-93 PF05978.11 KFX85811.1 - 0.65 9.4 14.1 0.31 10.5 2.2 2.6 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 NmrA PF05368.8 KFX85813.1 - 4.9e-19 68.5 0.0 6.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX85813.1 - 9.4e-10 38.7 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX85813.1 - 5e-06 26.1 0.0 7.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX85813.1 - 0.0034 16.1 0.0 0.0053 15.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KFX85813.1 - 0.0065 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 KFX85813.1 - 0.0088 16.4 0.5 0.022 15.1 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KFX85813.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 KFX85813.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KFX85813.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Choline_kin_N PF04428.9 KFX85813.1 - 0.12 11.8 0.1 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 Choline kinase N terminus Cellulase PF00150.13 KFX85816.1 - 1.9e-12 47.0 0.2 3.5e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_4 PF01565.18 KFX85817.1 - 2.3e-22 78.9 0.1 4.4e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Na_Ca_ex PF01699.19 KFX85818.1 - 0.033 13.7 2.6 0.44 10.1 2.6 2.2 1 1 1 2 2 2 0 Sodium/calcium exchanger protein FAD_binding_3 PF01494.14 KFX85822.1 - 5.3e-09 35.5 6.8 8.2e-07 28.3 1.3 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX85822.1 - 0.00055 19.9 1.4 0.0013 18.6 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX85822.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 KFX85822.1 - 0.0045 15.9 4.5 0.02 13.8 1.4 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX85822.1 - 0.051 13.4 0.7 0.13 12.1 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX85822.1 - 0.092 11.8 0.5 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KFX85822.1 - 0.14 10.9 1.2 0.58 8.9 0.6 1.9 2 0 0 2 2 2 0 FAD binding domain SE PF08491.5 KFX85822.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase MFS_1 PF07690.11 KFX85823.1 - 2.2e-17 62.7 27.8 6.4e-16 58.0 18.0 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 KFX85823.1 - 0.003 16.4 5.2 0.003 16.4 3.6 2.6 2 1 0 2 2 2 1 Acyltransferase family DUF2530 PF10745.4 KFX85823.1 - 0.18 11.8 2.1 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TPR_12 PF13424.1 KFX85826.1 - 6.4e-12 45.2 31.2 0.044 13.7 0.0 10.7 11 1 0 11 11 11 4 Tetratricopeptide repeat AAA_22 PF13401.1 KFX85826.1 - 5.2e-09 36.3 2.9 1.4e-08 34.9 0.1 3.3 2 1 0 2 2 2 1 AAA domain TPR_14 PF13428.1 KFX85826.1 - 6e-07 29.5 0.5 18 6.3 0.0 8.8 9 1 1 10 10 9 0 Tetratricopeptide repeat AAA_16 PF13191.1 KFX85826.1 - 2.1e-06 27.8 0.1 8.6e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TPR_10 PF13374.1 KFX85826.1 - 0.00016 21.4 4.3 0.15 12.0 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX85826.1 - 0.002 18.4 18.0 0.083 13.2 0.1 8.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX85826.1 - 0.0028 17.4 19.9 1.5 8.9 0.2 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX85826.1 - 0.012 15.3 19.1 5 7.1 0.1 9.0 9 0 0 9 9 8 0 Tetratricopeptide repeat AAA_19 PF13245.1 KFX85826.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TPR_6 PF13174.1 KFX85826.1 - 0.16 12.4 9.4 15 6.3 0.2 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX85826.1 - 3.2 7.4 16.3 1.1 8.9 0.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFX85826.1 - 4.7 6.9 16.4 17 5.1 0.1 6.0 5 2 2 7 7 7 0 TPR repeat Bystin PF05291.6 KFX85828.1 - 2.4e-125 417.4 0.0 3.2e-125 417.0 0.0 1.1 1 0 0 1 1 1 1 Bystin Gag_spuma PF03276.9 KFX85829.1 - 4.9 5.3 6.7 7.2 4.8 4.6 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Mito_fiss_reg PF05308.6 KFX85829.1 - 8.5 5.6 8.9 14 4.9 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Myb_Cef PF11831.3 KFX85833.1 - 0.00059 19.1 10.9 0.00065 18.9 7.6 1.0 1 0 0 1 1 1 1 pre-mRNA splicing factor component Calcyon PF06387.6 KFX85833.1 - 0.16 11.3 1.2 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) LEA_1 PF03760.10 KFX85833.1 - 0.24 11.5 14.9 0.31 11.2 10.3 1.3 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Di19_C PF14571.1 KFX85833.1 - 0.29 11.4 5.9 0.35 11.2 4.1 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF4288 PF14119.1 KFX85833.1 - 1.2 9.3 4.4 1.3 9.1 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Adeno_VII PF03228.9 KFX85833.1 - 3.5 8.2 7.4 3.8 8.1 5.1 1.0 1 0 0 1 1 1 0 Adenoviral core protein VII ATP-synt_E PF05680.7 KFX85833.1 - 7 6.6 10.6 8.9 6.3 7.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain Sec62 PF03839.11 KFX85833.1 - 8 5.7 7.1 8.1 5.7 4.9 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Trp_halogenase PF04820.9 KFX85834.1 - 1.2e-13 50.5 0.0 4.3e-05 22.3 0.0 3.5 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.19 KFX85834.1 - 0.0002 20.3 0.0 0.00048 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.10 KFX85834.1 - 0.00065 18.0 0.0 0.001 17.3 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 KFX85834.1 - 0.0022 18.0 0.0 0.034 14.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX85834.1 - 0.011 14.7 0.0 0.39 9.5 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KFX85834.1 - 0.044 12.8 0.0 0.4 9.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 KFX85834.1 - 0.12 12.7 0.0 0.78 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HORMA PF02301.13 KFX85835.1 - 1.1e-21 77.3 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KFX85835.1 - 0.0084 15.7 10.8 0.017 14.7 7.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFX85835.1 - 0.017 14.4 4.7 0.033 13.5 3.3 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 KFX85835.1 - 0.027 14.1 5.2 0.055 13.2 3.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1546 PF07571.8 KFX85836.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1546) ABC_tran PF00005.22 KFX85837.1 - 6.1e-51 172.3 0.0 4.2e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX85837.1 - 1.3e-30 106.7 41.7 3e-21 76.0 13.1 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX85837.1 - 4.3e-12 46.5 0.1 0.11 12.4 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFX85837.1 - 1.8e-11 43.7 2.4 0.015 14.5 0.0 4.2 2 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFX85837.1 - 1.1e-07 31.9 0.1 0.019 15.1 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX85837.1 - 1.1e-06 28.7 0.1 0.034 14.1 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFX85837.1 - 1.3e-06 27.6 0.3 0.01 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX85837.1 - 8e-06 25.2 0.2 0.21 11.1 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KFX85837.1 - 1.5e-05 25.4 0.1 0.31 11.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 KFX85837.1 - 3e-05 23.9 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFX85837.1 - 5.5e-05 23.5 0.4 0.067 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX85837.1 - 8.3e-05 22.0 0.3 0.43 9.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KFX85837.1 - 0.00011 22.1 0.0 0.36 10.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KFX85837.1 - 0.00015 22.5 0.0 0.043 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX85837.1 - 0.00042 19.8 0.0 0.73 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA PF00004.24 KFX85837.1 - 0.00047 20.3 0.3 3.9 7.6 0.0 3.7 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFX85837.1 - 0.00055 19.7 0.0 0.0084 15.8 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 KFX85837.1 - 0.0013 19.0 0.0 0.35 11.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KFX85837.1 - 0.0019 17.9 0.2 0.8 9.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFX85837.1 - 0.002 17.2 0.1 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 KFX85837.1 - 0.0035 17.5 0.0 4 7.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KFX85837.1 - 0.0066 16.3 0.0 0.59 10.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KFX85837.1 - 0.0086 15.9 1.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_5 PF07728.9 KFX85837.1 - 0.013 15.2 0.2 6.6 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 KFX85837.1 - 0.015 13.9 0.3 0.83 8.1 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Adeno_IVa2 PF02456.10 KFX85837.1 - 0.016 13.8 0.5 0.22 10.1 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.12 KFX85837.1 - 0.022 14.3 0.0 5.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 KFX85837.1 - 0.045 13.2 1.7 2.6 7.5 0.1 2.8 2 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 KFX85837.1 - 0.059 12.9 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 KFX85837.1 - 0.077 12.6 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 KFX85837.1 - 0.14 11.0 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 KFX85837.1 - 0.21 10.9 0.1 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_24 PF13479.1 KFX85837.1 - 0.23 11.0 0.3 22 4.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KFX85837.1 - 0.39 9.3 0.1 10 4.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein F-box PF00646.28 KFX85838.1 - 2.2e-05 23.9 0.2 4.8e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX85838.1 - 0.012 15.2 0.3 0.031 14.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like Actin PF00022.14 KFX85839.1 - 1.3e-15 56.8 0.0 2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Actin JAB PF01398.16 KFX85839.1 - 2.1e-07 30.6 0.0 5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFX85839.1 - 8.1e-05 22.6 0.0 0.0049 16.9 0.0 2.5 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function IDEAL PF08858.5 KFX85839.1 - 0.0032 16.9 0.1 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 IDEAL domain RRM_6 PF14259.1 KFX85840.1 - 1.3e-05 25.0 0.0 3.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX85840.1 - 0.0078 15.8 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTA1 PF04479.8 KFX85843.1 - 7.4e-42 143.3 9.3 7.4e-42 143.3 6.4 1.5 1 1 1 2 2 2 1 RTA1 like protein Zn_clus PF00172.13 KFX85844.1 - 2.6e-07 30.4 6.5 4.5e-07 29.6 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX85844.1 - 0.035 12.7 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain SH3_9 PF14604.1 KFX85846.1 - 1.8e-05 24.2 0.1 4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFX85846.1 - 0.0049 16.2 0.2 0.0098 15.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain DAP10 PF07213.6 KFX85846.1 - 0.045 13.5 0.4 0.25 11.1 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein Syndecan PF01034.15 KFX85846.1 - 0.21 11.2 0.5 0.45 10.2 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.10 KFX85846.1 - 0.32 10.5 1.9 1 8.9 1.3 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gly-zipper_YMGG PF13441.1 KFX85846.1 - 0.98 8.9 17.1 2.5 7.6 2.8 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF2668 PF10873.3 KFX85846.1 - 3.5 7.7 7.9 0.33 11.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) Asp-B-Hydro_N PF05279.6 KFX85848.1 - 2.8 7.7 10.7 3.3 7.4 7.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 KFX85852.1 - 1.3e-70 237.5 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX85852.1 - 1.4e-30 106.2 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFX85852.1 - 7.9e-14 51.9 0.3 3.1e-13 50.0 0.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFX85852.1 - 8.1e-09 34.8 0.0 1.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 KFX85852.1 - 1.6e-06 27.8 0.0 6.3e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 C2 domain APH PF01636.18 KFX85852.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX85852.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABM PF03992.11 KFX85856.1 - 2.4e-05 24.2 0.7 0.23 11.5 0.1 2.4 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.13 KFX85857.1 - 6.3e-07 28.5 0.1 1.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX85857.1 - 1.1e-05 25.2 9.0 2.2e-05 24.2 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX85858.1 - 1.9e-18 66.9 0.1 2.7e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX85858.1 - 1.3e-09 38.2 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX85858.1 - 7.8e-08 32.1 0.0 1.1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX85858.1 - 0.0075 16.2 0.0 0.028 14.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding AMP-binding PF00501.23 KFX85862.1 - 1.2e-65 221.5 0.0 2e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFX85862.1 - 3.4e-34 118.0 0.0 4.6e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KFX85862.1 - 8.5e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX85862.1 - 0.00026 21.8 0.1 0.00087 20.1 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E1-E2_ATPase PF00122.15 KFX85864.1 - 1e-50 171.9 0.1 4e-50 170.0 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX85864.1 - 2.2e-35 123.0 0.0 4.3e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFX85864.1 - 1.5e-28 98.7 4.2 2.7e-09 37.0 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KFX85864.1 - 1.4e-15 58.0 0.0 6.4e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX85864.1 - 0.00034 20.2 0.1 0.00056 19.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 KFX85864.1 - 0.026 14.4 0.4 25 4.9 0.0 3.8 4 0 0 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.17 KFX85865.1 - 4.7e-44 150.6 0.0 5.4e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KFX85867.1 - 2.3e-21 76.4 1.0 3.2e-21 75.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX85867.1 - 2.3e-12 46.9 0.1 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX85867.1 - 1.9e-08 34.3 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX85867.1 - 7.7e-05 22.2 0.2 0.00016 21.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX85867.1 - 0.00019 20.4 0.0 0.00022 20.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_tran_WecB PF03808.8 KFX85867.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family U-box PF04564.10 KFX85868.1 - 2e-05 24.4 0.0 8.8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 U-box domain Rtf2 PF04641.7 KFX85868.1 - 0.082 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SNF2_N PF00176.18 KFX85870.1 - 1.8e-73 246.9 0.6 3.6e-73 245.9 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX85870.1 - 9.2e-15 54.2 0.1 2.8e-14 52.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX85870.1 - 8.2e-08 32.2 0.0 8.2e-08 32.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX85870.1 - 6.7e-05 22.4 0.0 0.00018 21.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 KFX85870.1 - 0.00011 21.8 7.7 0.00011 21.8 5.3 3.3 2 1 1 3 3 3 1 HSA DEAD_2 PF06733.10 KFX85870.1 - 0.024 14.0 0.0 0.071 12.5 0.0 1.7 1 0 0 1 1 1 0 DEAD_2 Mito_carr PF00153.22 KFX85871.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein Cupin_2 PF07883.6 KFX85872.1 - 4.9e-21 74.0 0.2 4.1e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFX85872.1 - 7.6e-17 60.4 1.3 6.5e-13 47.8 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFX85872.1 - 3.3e-06 26.8 0.1 0.029 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.17 KFX85872.1 - 5.2e-06 25.9 0.0 0.00015 21.2 0.0 2.4 2 1 0 2 2 2 1 Cupin CENP-C_C PF11699.3 KFX85872.1 - 4.3e-05 23.4 0.0 0.00011 22.0 0.0 1.6 2 0 0 2 2 2 1 Mif2/CENP-C like DUF2697 PF10906.3 KFX85872.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) Cupin_6 PF12852.2 KFX85872.1 - 0.026 14.1 0.0 4 7.0 0.0 2.2 1 1 1 2 2 2 0 Cupin MannoseP_isomer PF01050.13 KFX85872.1 - 0.035 13.7 0.0 3.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Ala_racemase_N PF01168.15 KFX85874.1 - 7.6e-42 143.3 0.0 9.1e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DDE_1 PF03184.14 KFX85877.1 - 3.4e-14 52.4 0.0 5.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2435 PF10363.4 KFX85877.1 - 0.033 14.0 0.1 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) HeLo PF14479.1 KFX85878.1 - 5.8e-29 101.3 2.0 8.2e-25 87.7 0.1 2.0 1 1 1 2 2 2 2 Prion-inhibition and propagation DUF1192 PF06698.6 KFX85878.1 - 0.011 15.4 1.9 0.016 15.0 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) NACHT PF05729.7 KFX85879.1 - 1.3e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFX85879.1 - 5.4e-05 23.2 0.4 0.00058 19.8 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 KFX85879.1 - 0.0028 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 KFX85879.1 - 0.003 17.6 0.0 0.0066 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFX85879.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KFX85879.1 - 0.021 15.6 0.4 0.072 13.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX85879.1 - 0.027 14.2 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KFX85879.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFX85879.1 - 0.072 12.8 0.1 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KFX85879.1 - 0.15 12.2 0.1 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA helicase DUF4423 PF14394.1 KFX85879.1 - 0.17 11.4 0.1 0.72 9.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) KAP_NTPase PF07693.9 KFX85879.1 - 0.32 9.9 1.4 0.87 8.5 0.2 1.9 1 1 0 2 2 2 0 KAP family P-loop domain Omega-toxin PF06357.6 KFX85880.1 - 0.026 14.1 0.2 40 3.9 0.0 3.1 3 0 0 3 3 3 0 Omega-atracotoxin PMR5N PF14416.1 KFX85880.1 - 0.093 12.7 0.0 2.9 7.9 0.0 2.0 2 0 0 2 2 2 0 PMR5 N terminal Domain Dishevelled PF02377.10 KFX85880.1 - 0.19 11.9 1.5 0.59 10.3 0.2 2.0 1 1 1 2 2 2 0 Dishevelled specific domain HSDR_N_2 PF13588.1 KFX85882.1 - 0.05 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) F-box PF00646.28 KFX85883.1 - 0.033 13.8 0.2 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain Cpn60_TCP1 PF00118.19 KFX85887.1 - 1.6e-139 465.6 16.6 2e-139 465.3 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KFX85887.1 - 0.022 14.2 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF3924 PF13062.1 KFX85887.1 - 0.09 12.6 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) AAA PF00004.24 KFX85888.1 - 9.6e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX85888.1 - 4.7e-06 26.7 0.0 0.00059 19.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFX85888.1 - 2e-05 24.3 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX85888.1 - 0.00015 21.7 0.0 0.00071 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFX85888.1 - 0.00026 21.0 0.1 0.001 19.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KFX85888.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFX85888.1 - 0.0045 17.7 0.1 0.014 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX85888.1 - 0.0087 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFX85888.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KFX85888.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFX85888.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX85888.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX85888.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 KFX85888.1 - 0.051 12.6 0.1 5.2 6.1 0.0 2.6 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.6 KFX85888.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX85888.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KFX85888.1 - 0.071 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFX85888.1 - 0.073 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFX85888.1 - 0.1 12.1 0.0 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFX85888.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KFX85888.1 - 0.12 12.0 0.8 11 5.6 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 KFX85888.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KFX85888.1 - 0.15 11.4 0.2 0.42 9.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Laminin_II PF06009.7 KFX85890.1 - 0.68 9.6 8.9 0.75 9.5 4.8 2.0 1 1 1 2 2 2 0 Laminin Domain II Lebercilin PF15619.1 KFX85890.1 - 1.5 8.1 28.4 2.8 7.2 7.3 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Mito_carr PF00153.22 KFX85891.1 - 1.7e-66 219.9 5.1 6.9e-24 83.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RasGEF PF00617.14 KFX85893.1 - 1.7e-55 187.7 2.9 2.3e-55 187.2 0.2 2.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 KFX85893.1 - 2.8e-19 69.1 0.4 8.5e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 KFX85893.1 - 0.00084 18.6 0.0 0.0021 17.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX85893.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Mitofilin PF09731.4 KFX85894.1 - 2e-38 132.4 1.0 2e-38 132.4 0.7 1.4 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 KFX85894.1 - 0.27 11.2 5.0 0.1 12.6 0.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1151 PF06625.6 KFX85894.1 - 0.56 9.9 5.4 1 9.1 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Ras PF00071.17 KFX85895.1 - 9e-59 197.4 0.3 1e-58 197.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX85895.1 - 1.9e-19 70.3 0.1 3.2e-19 69.5 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KFX85895.1 - 1.8e-15 56.6 0.1 2.2e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX85895.1 - 1.9e-08 33.9 0.0 3.4e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFX85895.1 - 7.9e-08 31.7 0.0 9.7e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX85895.1 - 4.2e-06 26.7 0.0 6.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX85895.1 - 0.007 16.5 0.0 0.64 10.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 KFX85895.1 - 0.02 14.0 0.2 0.085 12.0 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX85895.1 - 0.045 13.7 0.3 0.12 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAT PF03417.11 KFX85895.1 - 0.061 12.7 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Amidase02_C PF12123.3 KFX85895.1 - 0.084 12.5 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_14 PF13173.1 KFX85895.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Syja_N PF02383.13 KFX85896.1 - 8.4e-92 307.3 0.0 1.1e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF3224 PF11528.3 KFX85898.1 - 2.7e-09 36.6 3.2 6.9e-09 35.3 2.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3224) AAA PF00004.24 KFX85900.1 - 3.3e-40 137.3 0.0 7.1e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX85900.1 - 0.00025 21.0 0.7 0.018 15.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KFX85900.1 - 0.00029 19.9 0.0 0.00059 18.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFX85900.1 - 0.00032 20.4 0.6 0.0013 18.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX85900.1 - 0.00033 20.7 0.3 0.02 15.0 0.0 3.0 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 KFX85900.1 - 0.00045 20.1 0.9 0.0047 16.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KFX85900.1 - 0.0013 18.0 0.2 0.028 13.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KFX85900.1 - 0.0086 15.2 0.0 0.024 13.8 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KFX85900.1 - 0.0099 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFX85900.1 - 0.015 14.2 0.0 0.035 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KFX85900.1 - 0.018 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KFX85900.1 - 0.023 14.0 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFX85900.1 - 0.038 13.3 1.4 0.33 10.3 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KFX85900.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFX85900.1 - 0.075 13.8 0.1 0.075 13.8 0.1 2.7 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KFX85900.1 - 0.19 11.2 2.1 0.6 9.6 0.0 2.4 2 2 0 2 2 2 0 AAA domain DUF1768 PF08719.6 KFX85901.1 - 2.2e-34 118.4 0.0 5.6e-34 117.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DDHD PF02862.12 KFX85901.1 - 0.31 10.8 12.2 0.51 10.0 8.4 1.4 1 0 0 1 1 1 0 DDHD domain CENP-T PF15511.1 KFX85901.1 - 0.31 10.2 25.7 0.39 9.9 17.8 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Vinculin PF01044.14 KFX85901.1 - 1.5 6.6 12.4 1.8 6.4 8.6 1.1 1 0 0 1 1 1 0 Vinculin family RR_TM4-6 PF06459.7 KFX85901.1 - 1.8 8.3 25.5 3.2 7.5 17.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DnaJ PF00226.26 KFX85903.1 - 5.5e-21 74.0 0.4 9.1e-21 73.3 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Chitin_synth_1 PF01644.12 KFX85905.1 - 5e-82 273.5 0.2 7.6e-82 272.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFX85905.1 - 9.1e-31 105.3 0.0 1.8e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFX85905.1 - 5.9e-21 74.4 5.6 3.3e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFX85905.1 - 1.7e-11 44.2 5.7 1.7e-11 44.2 3.9 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFX85905.1 - 1.2e-09 38.2 0.0 5.1e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Bac_export_2 PF01312.14 KFX85905.1 - 2.9 6.6 7.2 4.7 6.0 5.0 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family BRE1 PF08647.6 KFX85907.1 - 0.027 14.4 0.2 0.061 13.2 0.1 1.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-C2H2_4 PF13894.1 KFX85908.1 - 3.5e-05 23.8 13.5 0.008 16.4 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX85908.1 - 0.00032 20.8 13.0 0.052 13.9 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX85908.1 - 0.0076 16.4 4.5 0.0076 16.4 3.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain COX6A PF02046.10 KFX85908.1 - 0.039 13.8 0.2 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa zf-UBP PF02148.14 KFX85908.1 - 3.7 7.7 7.9 4.6 7.4 0.9 2.7 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ammonium_transp PF00909.16 KFX85912.1 - 1.3e-115 386.1 26.8 1.4e-115 385.9 18.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ytp1 PF10355.4 KFX85913.1 - 1e-83 280.6 16.5 1e-83 280.6 11.4 1.6 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFX85913.1 - 2.2e-32 110.7 1.5 2.2e-32 110.7 1.0 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Fungal_trans_2 PF11951.3 KFX85920.1 - 3.1e-25 88.5 6.4 2.5e-24 85.6 4.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KFX85921.1 - 8.8e-13 48.5 1.7 2.2e-12 47.2 1.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX85921.1 - 6.4e-06 25.9 0.1 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX85921.1 - 8.2e-05 22.4 0.4 0.00012 21.9 0.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX85921.1 - 0.0015 17.9 0.4 0.0058 16.0 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MT0933_antitox PF14013.1 KFX85921.1 - 0.049 13.7 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MT0933-like antitoxin protein HOOK PF05622.7 KFX85924.1 - 8.1e-12 43.7 71.8 2.6e-07 28.8 43.6 3.4 3 1 0 3 3 3 3 HOOK protein GFO_IDH_MocA PF01408.17 KFX85924.1 - 0.0022 18.4 0.3 0.0096 16.4 0.2 2.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF904 PF06005.7 KFX85924.1 - 0.013 15.7 0.4 0.013 15.7 0.3 8.8 5 1 2 7 7 7 0 Protein of unknown function (DUF904) NYD-SP28_assoc PF14775.1 KFX85924.1 - 0.013 15.1 1.6 0.013 15.1 1.1 5.6 5 1 1 6 6 6 0 Sperm tail C-terminal domain Peptidase_M4 PF01447.13 KFX85924.1 - 2.3 8.3 6.5 0.6 10.2 0.6 2.9 2 1 1 3 3 3 0 Thermolysin metallopeptidase, catalytic domain LysM PF01476.15 KFX85928.1 - 2.5e-09 36.8 0.0 0.00013 21.7 0.0 3.0 3 0 0 3 3 3 2 LysM domain PAN_4 PF14295.1 KFX85928.1 - 3e-06 26.8 22.9 0.0091 15.6 0.5 4.9 5 0 0 5 5 5 3 PAN domain PAN_2 PF08276.6 KFX85928.1 - 6.5e-05 22.6 10.5 0.22 11.4 0.2 3.6 3 0 0 3 3 3 3 PAN-like domain PAN_3 PF08277.7 KFX85928.1 - 0.0074 15.8 18.5 0.1 12.2 0.1 5.0 4 1 1 5 5 5 3 PAN-like domain Toxin_28 PF08115.6 KFX85928.1 - 1 9.0 5.2 0.72 9.5 0.8 2.6 2 0 0 2 2 2 0 SFI toxin family Med3 PF11593.3 KFX85928.1 - 1.7 7.8 4.8 2.5 7.2 3.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SOR_SNZ PF01680.12 KFX85929.1 - 1.4e-09 37.8 0.2 6.8e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 KFX85929.1 - 1.1e-07 31.1 0.5 1.4e-07 30.8 0.3 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KFX85929.1 - 0.0028 16.9 0.1 0.019 14.2 0.0 1.9 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 KFX85929.1 - 0.0056 15.8 0.6 0.0064 15.6 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.16 KFX85929.1 - 0.007 15.4 0.1 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 KFX85929.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.3 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Trp_syntA PF00290.15 KFX85929.1 - 0.021 13.3 0.0 0.025 13.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Dus PF01207.12 KFX85929.1 - 0.066 12.0 0.2 0.16 10.8 0.1 1.5 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 KFX85929.1 - 0.071 11.9 0.4 0.11 11.3 0.3 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase TMP-TENI PF02581.12 KFX85929.1 - 0.13 11.4 0.3 0.23 10.5 0.1 1.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Mpv17_PMP22 PF04117.7 KFX85931.1 - 1.7e-10 40.3 1.9 8.7e-10 38.0 0.7 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family UPF0154 PF03672.8 KFX85931.1 - 0.033 13.8 0.2 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) RseC_MucC PF04246.7 KFX85931.1 - 0.096 12.2 0.3 11 5.5 0.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC BRF1 PF07741.8 KFX85935.1 - 0.18 12.0 4.4 2.9 8.1 3.0 2.8 1 1 0 1 1 1 0 Brf1-like TBP-binding domain DZR PF12773.2 KFX85936.1 - 0.049 13.4 1.6 0.6 9.9 0.1 2.6 1 1 1 2 2 2 0 Double zinc ribbon ANTH PF07651.11 KFX85942.1 - 9.8e-67 224.5 0.4 1.2e-66 224.2 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFX85942.1 - 4.9e-10 39.3 0.0 7.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain TRP PF06011.7 KFX85944.1 - 4.3e-157 523.1 31.0 4.3e-157 523.1 21.5 1.3 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFX85944.1 - 1.1e-38 132.4 0.8 2.3e-38 131.4 0.6 1.6 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KFX85944.1 - 0.007 15.7 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Glycoprotein UL132 DUF1049 PF06305.6 KFX85944.1 - 0.17 11.3 0.1 0.17 11.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF843 PF05814.6 KFX85944.1 - 0.44 10.3 6.3 1.2 8.9 0.4 3.2 3 1 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) UAF_Rrn10 PF05234.6 KFX85945.1 - 0.00037 20.5 0.0 0.0005 20.0 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 KFX85946.1 - 4.6e-32 108.7 6.1 1.3e-10 40.7 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 KFX85946.1 - 9.1e-05 20.7 0.4 0.3 9.1 0.0 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 KFX85946.1 - 0.0085 15.8 0.1 0.65 9.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term CytochromB561_N PF09786.4 KFX85948.1 - 1.6 7.1 9.2 1.8 6.9 6.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ytp1 PF10355.4 KFX85949.1 - 5.6e-80 268.4 11.4 6.8e-80 268.1 5.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFX85949.1 - 2.3e-29 101.0 4.8 2.3e-29 101.0 3.3 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) K_oxygenase PF13434.1 KFX85949.1 - 7e-18 64.6 0.0 2.6e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFX85949.1 - 3e-12 47.0 0.1 5.6e-07 29.8 0.0 3.1 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX85949.1 - 2.6e-05 24.0 0.0 0.24 11.1 0.0 2.9 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KFX85949.1 - 0.012 15.7 0.1 0.096 12.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KFX85949.1 - 0.02 14.8 0.0 0.83 9.4 0.0 2.5 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KNOX1 PF03790.8 KFX85949.1 - 0.045 13.0 0.6 1.7 8.0 0.2 2.5 2 0 0 2 2 2 0 KNOX1 domain GIDA PF01134.17 KFX85949.1 - 0.047 12.5 0.0 0.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KFX85949.1 - 0.084 11.7 0.0 0.19 10.5 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KFX85949.1 - 0.12 12.1 0.0 0.89 9.2 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KFX85949.1 - 0.67 8.8 4.0 4.1 6.1 0.0 3.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX85949.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ArfGap PF01412.13 KFX85951.1 - 2.4e-36 124.0 0.5 2.9e-36 123.7 0.3 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF1083 PF06452.6 KFX85951.1 - 0.07 12.9 0.3 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1083) A2L_zn_ribbon PF08792.5 KFX85951.1 - 0.12 11.8 2.3 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain TIM21 PF08294.6 KFX85952.1 - 7.7e-39 132.6 0.1 2.3e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 TIM21 Xpo1 PF08389.7 KFX85952.1 - 5.6e-29 100.9 2.0 1.7e-28 99.4 0.8 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 KFX85952.1 - 1e-06 28.5 0.1 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Coa1 PF08695.5 KFX85952.1 - 2.7e-05 23.6 0.0 0.00011 21.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Adaptin_N PF01602.15 KFX85952.1 - 0.048 11.9 0.6 4.7 5.4 0.1 2.4 2 0 0 2 2 2 0 Adaptin N terminal region TPP_enzyme_N PF02776.13 KFX85957.1 - 1.5e-38 131.9 0.0 6.5e-38 129.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFX85957.1 - 2.4e-21 75.9 0.1 2.1e-20 72.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX85957.1 - 8.2e-21 74.1 0.0 1.9e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Nucleoplasmin PF03066.10 KFX85960.1 - 0.024 14.1 2.1 0.032 13.7 1.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF3079 PF11278.3 KFX85968.1 - 0.073 12.6 0.0 1 8.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3079) BTB PF00651.26 KFX85970.1 - 1.2e-05 25.2 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Lipase_3 PF01764.20 KFX85972.1 - 5.6e-06 26.0 0.0 9.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KFX85972.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KFX85972.1 - 0.047 13.4 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Actin PF00022.14 KFX85978.1 - 1.3e-158 527.6 0.0 1.4e-158 527.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFX85978.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) bZIP_1 PF00170.16 KFX85982.1 - 4.8e-09 36.0 11.4 4.8e-09 36.0 7.9 2.3 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 KFX85982.1 - 1.2e-05 25.0 10.4 1.2e-05 25.0 7.2 2.6 2 0 0 2 2 2 1 Basic region leucine zipper DUF904 PF06005.7 KFX85982.1 - 0.015 15.5 1.0 0.015 15.5 0.7 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFX85982.1 - 0.066 12.6 8.4 1.1 8.8 0.6 2.8 2 0 0 2 2 2 0 Septum formation initiator PfkB PF00294.19 KFX85985.1 - 8.8e-07 28.3 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MCM PF00493.18 KFX85986.1 - 1.6e-129 431.4 0.3 2.3e-129 430.9 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFX85986.1 - 4.1e-17 62.7 0.4 3.8e-16 59.6 0.0 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFX85986.1 - 2.9e-07 29.8 0.0 4e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFX85986.1 - 0.0023 17.5 0.0 0.0071 15.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFX85986.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain BPL_LplA_LipB PF03099.14 KFX85989.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.4 KFX85990.1 - 6e-66 222.2 0.0 7.6e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain IBN_N PF03810.14 KFX85992.1 - 1.4e-11 44.0 0.2 2.2e-10 40.2 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFX85992.1 - 0.00016 21.5 1.7 0.0041 17.0 0.1 3.7 3 1 0 3 3 3 1 Exportin 1-like protein CFEM PF05730.6 KFX85994.1 - 1.2e-11 44.2 13.7 2e-11 43.5 9.5 1.3 1 0 0 1 1 1 1 CFEM domain DUF1517 PF07466.6 KFX85994.1 - 3.1 6.7 5.8 4.2 6.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) PEPCK_ATP PF01293.15 KFX85996.1 - 3.2e-119 398.5 0.0 3.8e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KFX85996.1 - 0.023 15.0 0.1 8.9 6.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KFX85996.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MRFAP1 PF15155.1 KFX85996.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 Zn_clus PF00172.13 KFX85997.1 - 1.1e-07 31.6 11.7 2.9e-07 30.2 8.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.8 KFX86001.1 - 2.1e-10 39.4 11.5 2.8e-10 39.0 8.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX86001.1 - 4.2e-07 29.0 23.4 5.4e-07 28.6 14.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4405 PF14358.1 KFX86001.1 - 0.87 9.7 17.6 0.095 12.8 0.8 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) CBM_48 PF02922.13 KFX86005.1 - 0.001 19.0 0.1 0.0012 18.8 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM_25 PF03423.8 KFX86005.1 - 0.05 13.6 0.2 0.079 13.0 0.1 1.4 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) HCO3_cotransp PF00955.16 KFX86007.1 - 0.0016 17.1 2.5 0.0021 16.8 1.7 1.3 1 0 0 1 1 1 1 HCO3- transporter family HlyIII PF03006.15 KFX86007.1 - 0.031 13.6 4.2 0.044 13.1 2.9 1.1 1 0 0 1 1 1 0 Haemolysin-III related RIO1 PF01163.17 KFX86009.1 - 2.3e-05 23.8 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KFX86009.1 - 0.00064 19.5 0.2 0.0032 17.2 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KFX86009.1 - 0.014 14.5 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 KFX86009.1 - 0.026 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyltransferase PF01553.16 KFX86011.1 - 4.8e-13 48.6 0.0 7.1e-12 44.9 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase Tropomyosin_1 PF12718.2 KFX86012.1 - 0.0024 17.7 6.0 0.0024 17.7 4.1 2.0 1 1 1 2 2 2 1 Tropomyosin like Tup_N PF08581.5 KFX86012.1 - 0.0039 17.3 4.1 1.2 9.3 0.5 2.4 2 0 0 2 2 2 2 Tup N-terminal DUF3584 PF12128.3 KFX86012.1 - 0.022 12.1 6.2 0.025 11.9 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SCP-1 PF05483.7 KFX86012.1 - 0.025 12.3 6.5 0.03 12.1 4.5 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Rab5-bind PF09311.6 KFX86012.1 - 0.046 13.6 9.2 0.11 12.4 6.4 1.5 1 1 0 1 1 1 0 Rabaptin-like protein P4Ha_N PF08336.6 KFX86012.1 - 0.074 12.8 1.6 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.10 KFX86012.1 - 0.083 12.3 3.2 0.2 11.1 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Adeno_PIX PF03955.9 KFX86012.1 - 0.16 12.4 3.0 7 7.2 0.1 2.3 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) CENP-F_leu_zip PF10473.4 KFX86012.1 - 0.16 11.7 14.9 1.3 8.9 10.4 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hpt PF01627.18 KFX86012.1 - 0.39 10.7 4.1 4.7 7.2 2.1 2.6 2 1 0 2 2 2 0 Hpt domain DUF972 PF06156.8 KFX86012.1 - 0.48 10.8 8.4 0.32 11.3 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) YkyA PF10368.4 KFX86012.1 - 0.48 9.7 8.2 0.68 9.2 5.5 1.3 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Seryl_tRNA_N PF02403.17 KFX86012.1 - 0.64 10.0 10.7 3.1 7.8 0.7 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cauli_AT PF03233.8 KFX86012.1 - 0.69 9.6 2.9 11 5.6 0.1 2.3 1 1 1 2 2 2 0 Aphid transmission protein DUF3708 PF12501.3 KFX86012.1 - 1.1 9.0 3.1 1.1 9.0 1.3 1.6 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter DUF2205 PF10224.4 KFX86012.1 - 1.3 8.6 5.9 0.91 9.1 1.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF3560 PF12083.3 KFX86012.1 - 1.4 8.9 10.1 0.74 9.8 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) IncA PF04156.9 KFX86012.1 - 1.7 8.1 11.0 2.5 7.6 3.2 2.1 1 1 1 2 2 2 0 IncA protein Spc24 PF08286.6 KFX86012.1 - 1.8 8.2 5.2 1.9 8.1 0.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 VASP_tetra PF08776.6 KFX86012.1 - 2.5 7.5 6.4 6.1 6.2 0.7 2.7 2 0 0 2 2 2 0 VASP tetramerisation domain CENP-H PF05837.7 KFX86012.1 - 3.1 8.0 9.9 1.3 9.2 0.9 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) zf-CpG_bind_C PF12269.3 KFX86012.1 - 4.6 6.6 8.1 1.7 8.0 0.6 2.2 1 1 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Cep57_CLD_2 PF14197.1 KFX86012.1 - 5.2 7.0 12.5 0.66 9.9 1.1 2.8 3 1 0 3 3 2 0 Centrosome localisation domain of PPC89 APG6 PF04111.7 KFX86012.1 - 6 5.8 7.8 11 4.9 5.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 KFX86012.1 - 8.2 6.4 12.9 3.3 7.7 1.2 2.6 1 1 2 3 3 3 0 DivIVA protein DUF2564 PF10819.3 KFX86012.1 - 9.7 6.3 7.3 4.2 7.5 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) PH PF00169.24 KFX86013.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 KFX86013.1 - 0.036 13.5 0.5 0.069 12.6 0.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Latarcin PF10279.4 KFX86016.1 - 3.1 8.0 6.1 0.95 9.6 1.8 2.0 2 0 0 2 2 2 0 Latarcin precursor Fungal_trans PF04082.13 KFX86018.1 - 6.5e-27 94.0 0.0 1.5e-26 92.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX86018.1 - 4.4e-05 23.2 13.1 7.8e-05 22.4 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX86020.1 - 7.4e-31 107.1 29.6 3.8e-30 104.7 21.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KFX86020.1 - 0.1 12.6 0.1 0.1 12.6 0.1 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) IBR PF01485.16 KFX86024.1 - 5.6e-07 29.3 31.8 0.00034 20.4 2.4 3.5 3 0 0 3 3 3 2 IBR domain Myosin_head PF00063.16 KFX86028.1 - 8.5e-11 40.6 0.0 1.1e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Mt_ATP-synt_D PF05873.7 KFX86030.1 - 1.2e-18 67.3 0.7 1.5e-18 66.9 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4515 PF14988.1 KFX86030.1 - 0.012 15.2 2.1 0.18 11.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) E3_UbLigase_R4 PF13764.1 KFX86030.1 - 0.037 11.9 0.5 0.043 11.7 0.4 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 CCDC155 PF14662.1 KFX86030.1 - 0.042 13.4 2.7 0.15 11.6 0.7 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF3544 PF12064.3 KFX86030.1 - 0.077 12.7 0.2 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) V_ATPase_I PF01496.14 KFX86030.1 - 0.12 10.1 1.1 0.14 9.9 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.9 KFX86030.1 - 0.22 10.9 1.3 0.34 10.2 0.3 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.5 KFX86030.1 - 0.3 11.1 3.4 0.31 11.1 1.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.6 KFX86030.1 - 0.33 11.1 4.0 0.63 10.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Syntaxin PF00804.20 KFX86030.1 - 0.77 9.9 5.7 0.74 10.0 1.4 2.0 1 1 1 2 2 2 0 Syntaxin XhlA PF10779.4 KFX86030.1 - 1.5 8.7 6.2 1.3 9.0 2.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA NAC PF01849.13 KFX86031.1 - 5.9e-25 86.5 0.2 5.8e-24 83.3 0.1 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KFX86031.1 - 0.0083 15.9 0.2 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain FIST_C PF10442.4 KFX86031.1 - 0.14 12.1 0.3 1.3 8.9 0.0 2.3 2 1 0 2 2 2 0 FIST C domain SelP_N PF04592.9 KFX86031.1 - 1.3 8.3 6.5 2.2 7.5 4.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.9 KFX86031.1 - 5.5 4.8 12.1 0.085 10.8 3.3 1.5 2 0 0 2 2 2 0 CDC45-like protein Flavodoxin_1 PF00258.20 KFX86033.1 - 5.4e-10 39.4 0.0 7.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KFX86033.1 - 5e-09 35.8 0.1 6.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFX86033.1 - 0.00038 20.0 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Bacteriocin_IIc PF10439.4 KFX86033.1 - 4.8 7.3 8.4 13 5.9 3.9 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide E1-E2_ATPase PF00122.15 KFX86035.1 - 1.2e-63 214.2 0.4 1.2e-63 214.2 0.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KFX86035.1 - 7.4e-23 82.0 0.2 2.1e-22 80.6 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX86035.1 - 2.5e-13 50.6 0.0 6.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX86035.1 - 6.1e-10 38.4 0.0 1.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFX86035.1 - 0.0012 18.4 0.1 0.0031 17.1 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX86035.1 - 0.0027 17.6 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Glyco_tranf_2_3 PF13641.1 KFX86039.1 - 4.5e-22 78.9 0.1 1.9e-21 76.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFX86039.1 - 2.6e-08 33.7 0.0 2.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KFX86039.1 - 4.5e-08 32.5 0.2 2.5e-07 30.1 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 PPR_3 PF13812.1 KFX86042.1 - 2.6e-05 24.1 0.1 0.082 13.2 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFX86042.1 - 0.0095 15.8 0.1 0.56 10.2 0.0 2.6 2 1 1 3 3 3 2 PPR repeat family Acyl-CoA_dh_N PF02771.11 KFX86042.1 - 0.072 13.6 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain PPR PF01535.15 KFX86042.1 - 0.15 12.0 0.2 15 5.8 0.1 2.9 3 0 0 3 3 3 0 PPR repeat Nup84_Nup100 PF04121.8 KFX86044.1 - 8.6e-52 175.7 3.9 1.6e-51 174.8 0.5 2.7 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 PAS_9 PF13426.1 KFX86045.1 - 5.4e-28 97.4 0.0 1.6e-14 54.1 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KFX86045.1 - 7.1e-18 64.4 0.0 1.4e-12 47.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 KFX86045.1 - 1.6e-16 60.0 0.0 8.3e-08 32.0 0.0 3.8 3 1 0 3 3 3 3 PAS fold PAS_4 PF08448.5 KFX86045.1 - 4.2e-13 49.2 0.0 6.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 KFX86045.1 - 1.5e-09 37.8 0.0 4.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.1 KFX86045.1 - 0.0013 18.5 0.0 0.21 11.5 0.0 2.8 3 0 0 3 3 3 1 PAS domain RPEL PF02755.10 KFX86045.1 - 9.1 5.7 13.0 21 4.6 0.5 3.9 3 0 0 3 3 3 0 RPEL repeat KH_1 PF00013.24 KFX86047.1 - 1.2e-25 88.9 2.1 8.7e-08 31.6 0.2 7.5 8 0 0 8 8 8 4 KH domain KH_3 PF13014.1 KFX86047.1 - 2.2e-24 84.5 4.4 1.4e-06 27.8 0.0 5.6 5 0 0 5 5 5 5 KH domain Na_H_Exchanger PF00999.16 KFX86048.1 - 2.3e-21 75.7 30.9 3.4e-19 68.6 8.4 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family COG4 PF08318.7 KFX86056.1 - 3.5e-78 262.6 0.0 4.5e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein ABC_tran PF00005.22 KFX86059.1 - 1.7e-43 148.2 0.2 1.7e-26 93.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KFX86059.1 - 1.1e-28 100.3 22.7 1.6e-28 99.9 15.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region MMR_HSR1 PF01926.18 KFX86059.1 - 1.4e-06 28.1 0.2 0.033 14.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KFX86059.1 - 3.4e-06 27.2 3.0 0.17 11.8 0.1 4.5 4 1 0 4 4 4 1 AAA domain Miro PF08477.8 KFX86059.1 - 5.3e-06 26.9 1.5 0.064 13.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 KFX86059.1 - 1.6e-05 24.0 0.1 0.012 14.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 KFX86059.1 - 3.2e-05 23.3 2.5 0.15 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KFX86059.1 - 4.6e-05 22.7 1.9 0.17 11.1 0.1 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFX86059.1 - 0.00019 21.4 1.3 0.55 10.1 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KFX86059.1 - 0.0019 17.7 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 KFX86059.1 - 0.0039 17.3 0.6 5 7.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFX86059.1 - 0.0062 16.1 1.8 2.1 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX86059.1 - 0.011 15.1 0.3 4.4 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KFX86059.1 - 0.013 15.3 8.7 0.12 12.2 0.2 3.0 3 0 0 3 3 3 0 Dynamin family MobB PF03205.9 KFX86059.1 - 0.025 14.2 0.6 6.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFX86059.1 - 0.032 15.0 9.3 1.2 9.9 0.2 3.5 2 2 1 3 3 3 0 AAA domain DUF258 PF03193.11 KFX86059.1 - 0.036 13.2 4.0 2.8 7.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX86059.1 - 0.073 13.3 7.0 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KFX86059.1 - 0.085 12.8 2.4 0.19 11.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 KFX86059.1 - 0.11 12.1 0.2 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 KFX86059.1 - 0.24 10.8 2.9 5.3 6.5 0.3 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KFX86059.1 - 0.31 11.3 3.4 19 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KFX86059.1 - 0.38 10.5 2.1 2.1 8.1 0.3 2.8 2 0 0 2 2 2 0 Part of AAA domain TrwB_AAD_bind PF10412.4 KFX86059.1 - 0.39 9.2 2.9 5.1 5.6 0.2 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KFX86059.1 - 2.1 7.7 5.1 12 5.3 0.1 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family ArgK PF03308.11 KFX86059.1 - 6 5.5 8.1 2.3 6.9 0.1 2.5 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 KFX86059.1 - 6.2 6.5 12.6 0.15 11.9 0.3 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 SQS_PSY PF00494.14 KFX86061.1 - 1.2e-38 132.9 0.0 1.8e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4139 PF13598.1 KFX86066.1 - 1.5e-16 60.6 0.5 1.5e-16 60.6 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KFX86066.1 - 2.9e-11 43.7 0.2 2.9e-11 43.7 0.1 4.0 1 1 2 3 3 3 1 N-terminal domain of unknown function (DUF4140) Sigma70_ner PF04546.8 KFX86066.1 - 2.6 7.6 26.0 0.17 11.4 7.8 2.2 1 1 1 2 2 2 0 Sigma-70, non-essential region PXA PF02194.10 KFX86066.1 - 3.4 7.2 7.3 6.7 6.2 5.1 1.5 1 0 0 1 1 1 0 PXA domain His_Phos_1 PF00300.17 KFX86068.1 - 7.7e-33 113.8 0.1 1.8e-32 112.6 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KFX86068.1 - 0.0078 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1192 PF06698.6 KFX86069.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Myb_DNA-bind_3 PF12776.2 KFX86070.1 - 3.8 8.2 12.6 2.6 8.7 0.1 3.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SAS4 PF15460.1 KFX86073.1 - 9.5e-35 118.5 0.2 2.4e-34 117.2 0.1 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.4 KFX86073.1 - 0.0032 17.7 1.9 0.0032 17.7 1.3 2.4 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 MFS_1 PF07690.11 KFX86078.1 - 2.2e-13 49.6 22.0 2.3e-13 49.6 14.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KFX86078.1 - 0.00087 17.8 13.1 0.0017 16.8 1.1 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like Ferrochelatase PF00762.14 KFX86079.1 - 3.1e-35 121.6 0.0 3.5e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF2742 PF10888.3 KFX86079.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) GMC_oxred_C PF05199.8 KFX86081.1 - 4.5e-14 52.9 0.2 1.1e-13 51.6 0.1 1.7 1 1 1 2 2 2 1 GMC oxidoreductase DPBB_1 PF03330.13 KFX86082.1 - 1e-05 25.4 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 KFX86082.1 - 0.0086 16.0 0.1 0.01 15.8 0.1 1.0 1 0 0 1 1 1 1 Cerato-platanin BPL_C PF02237.12 KFX86082.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain RNA_pol PF00940.14 KFX86083.1 - 7.2e-06 24.7 1.2 7.2e-06 24.7 0.8 1.2 1 1 0 1 1 1 1 DNA-dependent RNA polymerase CDC45 PF02724.9 KFX86083.1 - 0.053 11.5 2.3 0.075 11.0 1.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KFX86083.1 - 0.077 10.9 7.7 0.087 10.7 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family EB1_binding PF05937.6 KFX86083.1 - 0.077 13.3 0.3 0.15 12.4 0.2 1.5 1 1 0 1 1 1 0 EB-1 Binding Domain BSP_II PF05432.6 KFX86083.1 - 0.12 11.6 9.4 0.14 11.3 6.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Daxx PF03344.10 KFX86083.1 - 0.28 9.6 8.5 0.4 9.1 5.9 1.3 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 KFX86083.1 - 0.64 9.7 3.4 1.2 8.8 2.3 1.4 1 0 0 1 1 1 0 FAM176 family TEX19 PF15553.1 KFX86083.1 - 0.89 9.4 4.4 1.7 8.5 3.0 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 BUD22 PF09073.5 KFX86083.1 - 0.9 8.5 13.2 1.2 8.1 9.2 1.2 1 1 0 1 1 1 0 BUD22 DUF4637 PF15470.1 KFX86083.1 - 1 8.9 7.8 1.6 8.3 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2956 PF11169.3 KFX86083.1 - 1 9.3 7.1 0.16 11.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) PRTP PF01366.13 KFX86083.1 - 1.4 6.8 3.4 1.6 6.5 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF2457 PF10446.4 KFX86083.1 - 1.5 7.4 13.4 2.2 6.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 KFX86083.1 - 3.8 6.4 7.0 5 6.0 4.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.14 KFX86083.1 - 3.9 7.9 15.6 7.7 6.9 10.8 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.3 KFX86083.1 - 5.6 6.8 16.5 2.7 7.8 10.2 1.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Condensation PF00668.15 KFX86084.1 - 2e-27 95.8 0.0 2e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Condensation domain DUF4238 PF14022.1 KFX86088.1 - 3.6e-11 42.8 0.0 2.1e-10 40.3 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4238) Pkinase PF00069.20 KFX86092.1 - 6.9e-06 25.4 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 KFX86092.1 - 5.8e-05 22.5 0.0 9.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.6 KFX86092.1 - 9.1e-05 21.7 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KFX86092.1 - 0.00014 21.7 0.9 0.0006 19.6 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX86092.1 - 0.00043 19.4 0.1 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1059 PF06348.6 KFX86092.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) RIO1 PF01163.17 KFX86092.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 KFX86094.1 - 1.3e-68 224.6 13.1 7.2e-11 41.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KFX86094.1 - 2.4e-27 94.9 5.8 3.7e-27 94.3 4.0 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KFX86094.1 - 0.0026 15.9 0.1 0.38 8.8 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFX86094.1 - 0.0048 16.0 0.0 2.5 7.1 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KFX86094.1 - 0.0061 15.3 0.2 0.69 8.5 0.1 2.8 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFX86094.1 - 0.063 11.5 0.7 0.6 8.3 0.3 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF3037 PF11236.3 KFX86094.1 - 0.2 11.7 0.2 0.38 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) DUF3772 PF12607.3 KFX86096.1 - 0.19 11.4 2.2 57 3.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) 2OG-FeII_Oxy_2 PF13532.1 KFX86098.1 - 4.6e-22 78.8 0.0 5.9e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KFX86098.1 - 0.0014 18.4 3.8 0.0026 17.6 2.6 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 KFX86098.1 - 0.043 14.1 0.1 0.079 13.2 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NicO PF03824.11 KFX86099.1 - 3e-44 151.4 7.6 3.5e-44 151.2 5.3 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF883 PF05957.8 KFX86102.1 - 0.12 12.7 6.4 0.22 11.9 1.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CsbD PF05532.7 KFX86102.1 - 2.4 7.9 21.1 0.5 10.0 9.7 3.4 2 2 0 2 2 2 0 CsbD-like ISG65-75 PF11727.3 KFX86102.1 - 7.5 5.5 10.6 13 4.7 7.3 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein CLTH PF10607.4 KFX86107.1 - 4.1e-28 97.8 0.0 5.8e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFX86107.1 - 4.7e-26 91.3 0.2 7.7e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KFX86107.1 - 0.00021 20.9 0.0 0.00021 20.9 0.0 2.3 3 0 0 3 3 3 1 LisH Glyco_hydro_16 PF00722.16 KFX86110.1 - 1.1e-09 37.8 0.1 7.2e-09 35.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 BSP_II PF05432.6 KFX86112.1 - 1.6 7.9 12.5 2.5 7.3 8.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 KFX86112.1 - 9.1 5.9 6.8 14 5.2 4.3 1.7 1 1 0 1 1 1 0 FAM176 family K_oxygenase PF13434.1 KFX86117.1 - 1.7e-104 349.4 0.0 2.1e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFX86117.1 - 2.5e-11 43.6 0.5 1.3e-07 31.5 0.0 3.1 2 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX86117.1 - 3.8e-10 40.1 0.0 1.2e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX86117.1 - 7.3e-06 26.0 0.0 0.0014 18.5 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Endostatin PF06482.6 KFX86117.1 - 0.22 10.8 0.5 0.34 10.2 0.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Herpes_UL32 PF06070.6 KFX86117.1 - 1.1 7.6 7.9 1.6 7.1 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Amidase PF01425.16 KFX86124.1 - 3.7e-85 286.4 0.0 4.6e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Acetyltransf_3 PF13302.1 KFX86126.1 - 3.9e-14 53.0 0.0 5.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX86126.1 - 1.1e-12 47.8 0.1 1.8e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KFX86126.1 - 6.8e-07 29.3 0.0 9.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX86126.1 - 0.00027 21.0 0.0 0.00048 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFX86126.1 - 0.015 15.2 0.0 0.023 14.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX86126.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein HSP70 PF00012.15 KFX86127.1 - 8.3e-11 40.5 0.4 7.7e-10 37.3 0.1 2.0 2 0 0 2 2 2 1 Hsp70 protein zf-SAP30 PF13866.1 KFX86127.1 - 0.0069 16.0 0.1 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KFX86127.1 - 0.016 13.8 0.1 0.14 10.7 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein BBE PF08031.7 KFX86128.1 - 0.025 14.4 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like zf-CCHC PF00098.18 KFX86129.1 - 3.7e-05 23.4 0.6 5.5e-05 22.9 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle AAA_17 PF13207.1 KFX86131.1 - 1.1e-06 29.5 0.0 1.3e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFX86131.1 - 0.00038 19.2 0.0 0.00041 19.1 0.0 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KFX86131.1 - 0.0004 20.5 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase SKI PF01202.17 KFX86131.1 - 0.00075 19.3 0.0 0.00095 19.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 KFX86131.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFX86131.1 - 0.0022 17.6 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KFX86131.1 - 0.0029 17.7 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX86131.1 - 0.0032 16.5 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KFX86131.1 - 0.0033 17.3 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX86131.1 - 0.0039 17.4 0.1 0.005 17.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX86131.1 - 0.0052 16.5 0.1 0.0081 15.8 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain CbiA PF01656.18 KFX86131.1 - 0.0067 15.8 0.0 0.0082 15.5 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KFX86131.1 - 0.0069 15.8 0.1 0.0069 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX86131.1 - 0.0071 16.3 0.1 0.0072 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Cytidylate_kin2 PF13189.1 KFX86131.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_5 PF07728.9 KFX86131.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 KFX86131.1 - 0.021 14.0 0.1 0.021 14.0 0.1 1.1 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 KFX86131.1 - 0.025 13.7 0.1 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KFX86131.1 - 0.029 14.6 0.0 0.034 14.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KFX86131.1 - 0.032 13.4 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFX86131.1 - 0.037 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFX86131.1 - 0.037 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KFX86131.1 - 0.059 12.3 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KFX86131.1 - 0.06 13.3 0.1 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KFX86131.1 - 0.12 12.3 0.1 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KFX86131.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.13 KFX86131.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family 2-oxoacid_dh PF00198.18 KFX86132.1 - 6.1e-56 189.2 0.3 6.8e-56 189.1 0.2 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Cellulase PF00150.13 KFX86136.1 - 7.8e-13 48.2 0.1 1.2e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FTA2 PF13095.1 KFX86138.1 - 0.012 15.2 0.0 0.013 15.1 0.0 1.0 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NAD_binding_2 PF03446.10 KFX86142.1 - 5.8e-13 49.0 0.1 5.9e-13 48.9 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KFX86142.1 - 0.061 13.4 0.0 0.064 13.3 0.0 1.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KFX86142.1 - 0.071 12.2 0.1 0.079 12.1 0.0 1.0 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFX86142.1 - 0.072 13.5 0.1 0.076 13.4 0.0 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF863 PF05904.6 KFX86146.1 - 0.054 11.7 1.7 0.055 11.7 1.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) PXA PF02194.10 KFX86148.1 - 4.2e-12 46.0 0.0 5.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 PXA domain DUF1688 PF07958.6 KFX86154.1 - 1.7e-179 596.7 0.0 2e-179 596.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Pex14_N PF04695.8 KFX86158.1 - 2.3e-12 47.1 0.2 2.3e-12 47.1 0.1 1.8 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_76 PF03663.9 KFX86161.1 - 2.6e-50 171.8 6.5 3.1e-50 171.6 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFX86161.1 - 0.0064 15.5 0.5 0.0069 15.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 PDEase_I PF00233.14 KFX86162.1 - 4e-44 151.1 0.7 1.5e-40 139.4 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HMG_box PF00505.14 KFX86169.1 - 2.2e-24 85.4 0.6 4.1e-24 84.6 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX86169.1 - 6e-20 71.3 1.2 6e-20 71.3 0.8 1.7 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 KFX86169.1 - 0.0013 18.5 0.8 0.0013 18.5 0.6 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 YABBY PF04690.8 KFX86169.1 - 0.045 13.9 1.5 0.049 13.8 0.6 1.4 1 1 0 1 1 1 0 YABBY protein DUF1014 PF06244.7 KFX86169.1 - 0.065 13.4 0.1 0.065 13.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) MFS_1 PF07690.11 KFX86172.1 - 3.7e-17 62.0 12.3 5e-17 61.6 8.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX86172.1 - 4e-16 58.6 9.3 4.6e-16 58.4 6.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX86172.1 - 5e-05 21.8 1.0 6.8e-05 21.4 0.7 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Alginate_lyase PF05426.7 KFX86172.1 - 0.03 13.6 0.1 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 Alginate lyase Transgly_assoc PF04226.8 KFX86172.1 - 0.057 13.5 3.7 1.2 9.2 0.3 2.9 2 1 1 3 3 3 0 Transglycosylase associated protein RRM_1 PF00076.17 KFX86176.1 - 2.3e-16 59.1 0.0 3.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX86176.1 - 4.6e-14 52.1 0.0 7.2e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86176.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 KFX86176.1 - 0.0017 18.0 0.1 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 IncA protein GAS PF13851.1 KFX86176.1 - 0.0097 15.1 1.0 0.013 14.7 0.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KFX86176.1 - 0.019 14.0 0.9 0.023 13.7 0.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Fmp27_WPPW PF10359.4 KFX86176.1 - 0.024 13.0 0.1 0.03 12.7 0.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF724 PF05266.9 KFX86176.1 - 0.025 14.1 4.2 0.036 13.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) EMP24_GP25L PF01105.19 KFX86176.1 - 0.025 14.2 1.3 0.035 13.8 0.9 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF972 PF06156.8 KFX86176.1 - 0.073 13.4 0.7 0.1 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KFX86176.1 - 0.074 10.9 0.2 0.081 10.7 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.1 KFX86176.1 - 0.2 11.5 1.4 0.49 10.2 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DivIC PF04977.10 KFX86176.1 - 0.85 9.1 3.9 1.4 8.4 2.7 1.3 1 0 0 1 1 1 0 Septum formation initiator CBM_1 PF00734.13 KFX86179.1 - 4.5e-10 38.9 2.5 5.6e-10 38.6 1.8 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Aconitase PF00330.15 KFX86181.1 - 8.6e-71 238.7 0.5 9.6e-71 238.6 0.3 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) GPI-anchored PF10342.4 KFX86183.1 - 3.6e-10 40.1 0.1 5.2e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyclin PF08613.6 KFX86184.1 - 2e-40 138.6 0.0 2.3e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX86184.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF3301 PF11743.3 KFX86184.1 - 0.14 11.6 0.0 9.6 5.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3301) DUF2458 PF10454.4 KFX86185.1 - 1.5e-40 138.5 0.0 2.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) V-ATPase_C PF03223.10 KFX86187.1 - 9.1e-97 324.2 0.1 9.9e-97 324.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.15 KFX86188.1 - 4.4e-68 227.8 0.0 5.4e-68 227.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KFX86188.1 - 8.6e-07 29.8 0.0 1.6e-06 28.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX86188.1 - 1.1e-05 25.2 0.0 1.5e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX86188.1 - 6.3e-05 23.2 0.0 0.00011 22.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFX86188.1 - 0.00076 18.7 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KFX86188.1 - 0.013 14.9 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KFX86188.1 - 0.043 12.9 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.13 KFX86188.1 - 0.075 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CPT PF07931.7 KFX86188.1 - 0.08 12.5 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2012 PF09430.5 KFX86193.1 - 2.4e-07 30.5 0.1 4.5e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2012) PAP1 PF08601.5 KFX86194.1 - 2.5e-40 139.2 0.2 2.9e-40 139.0 0.2 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 DUF155 PF02582.9 KFX86196.1 - 5e-56 189.3 0.3 6.4e-56 189.0 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 KFX86196.1 - 0.024 14.8 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 BLVR PF06375.6 KFX86198.1 - 0.0016 18.3 0.4 0.0017 18.2 0.3 1.0 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Nucleoplasmin PF03066.10 KFX86198.1 - 0.029 13.8 0.2 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin ComA PF02679.10 KFX86199.1 - 4e-73 245.4 0.0 4.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.3 KFX86199.1 - 0.09 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) Prenyltrans_1 PF13243.1 KFX86200.1 - 0.17 11.8 0.8 2.1 8.4 0.0 2.5 2 1 1 3 3 3 0 Prenyltransferase-like Cast PF10174.4 KFX86202.1 - 0.032 12.2 0.6 0.037 12.0 0.4 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.7 KFX86202.1 - 0.058 13.6 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.7 KFX86202.1 - 0.12 12.2 0.2 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 MbeD/MobD like HOOK PF05622.7 KFX86202.1 - 0.2 9.4 2.0 2.5 5.7 0.0 2.0 2 0 0 2 2 2 0 HOOK protein Aldose_epim PF01263.15 KFX86205.1 - 1.3e-22 80.3 0.0 1.5e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Abhydrolase_5 PF12695.2 KFX86205.1 - 0.1 12.3 0.0 0.41 10.3 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family S-methyl_trans PF02574.11 KFX86208.1 - 2.4e-26 92.7 0.0 1e-25 90.7 0.0 1.8 1 1 0 1 1 1 1 Homocysteine S-methyltransferase PvlArgDC PF01862.11 KFX86208.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) DUF4643 PF15485.1 KFX86210.1 - 0.053 13.0 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) NIF PF03031.13 KFX86212.1 - 1.4e-28 99.5 0.0 3e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KFX86212.1 - 1.9e-10 40.4 0.2 3.7e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFX86212.1 - 2.9e-06 27.3 0.0 6.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Acetyltransf_1 PF00583.19 KFX86214.1 - 1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFX86214.1 - 0.00029 20.5 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KFX86214.1 - 0.024 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX86214.1 - 0.036 14.1 0.0 0.073 13.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX86214.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Hydrolase_6 PF13344.1 KFX86218.1 - 1.1e-21 76.6 0.0 2.8e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX86218.1 - 1.5e-17 63.0 0.0 4.6e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFX86218.1 - 0.0002 21.6 0.0 0.26 11.4 0.0 3.3 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX86218.1 - 0.012 16.0 0.0 0.2 12.0 0.0 2.6 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Peptidase_M7 PF02031.11 KFX86221.1 - 0.067 12.9 1.3 0.074 12.7 0.9 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Cyclin_N PF00134.18 KFX86228.1 - 7.7e-05 22.2 0.2 0.0012 18.4 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KFX86228.1 - 0.0014 18.3 1.3 0.048 13.4 0.3 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 KFX86228.1 - 0.0044 16.9 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Lactamase_B PF00753.22 KFX86229.1 - 1e-08 35.0 0.0 2.7e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX86229.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFX86229.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain P3A PF08727.6 KFX86230.1 - 0.071 12.4 0.4 0.39 10.0 0.0 2.1 1 1 1 2 2 2 0 Poliovirus 3A protein like DUF3231 PF11553.3 KFX86230.1 - 0.099 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) Vac_ImportDeg PF09783.4 KFX86237.1 - 8.9e-70 233.7 0.4 1.2e-69 233.3 0.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Amidohydro_5 PF13594.1 KFX86238.1 - 4e-16 58.5 0.3 6.1e-16 57.9 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KFX86238.1 - 2.3e-05 24.5 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX86238.1 - 0.0022 17.7 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX86238.1 - 0.042 13.0 0.1 0.05 12.8 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase family DUF1749 PF08538.5 KFX86241.1 - 2.4e-97 325.4 0.1 3e-97 325.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KFX86241.1 - 3.5e-05 23.7 0.0 5.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX86241.1 - 0.00031 20.4 0.0 0.00088 19.0 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KFX86241.1 - 0.016 14.5 0.2 0.33 10.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KFX86241.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase TPR_1 PF00515.23 KFX86243.1 - 7.5e-14 50.6 0.5 1.5e-06 27.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX86243.1 - 7.8e-14 51.0 0.8 5.6e-07 29.1 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KFX86243.1 - 5.4e-08 32.1 0.6 0.0027 17.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX86243.1 - 0.00027 21.5 0.1 0.00089 19.8 0.0 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX86243.1 - 0.00052 20.4 0.3 0.041 14.5 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX86243.1 - 0.0042 17.3 0.2 0.043 14.1 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX86243.1 - 0.01 15.9 0.3 0.2 11.9 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFX86243.1 - 0.018 14.8 0.8 0.12 12.2 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX86243.1 - 0.032 14.0 0.2 2.2 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX86243.1 - 0.06 13.4 0.1 0.27 11.3 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 KFX86243.1 - 0.061 12.0 0.0 0.061 12.0 0.0 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.1 KFX86243.1 - 0.087 12.7 0.4 1.1 9.2 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat ProQ PF04352.8 KFX86243.1 - 0.099 12.2 1.8 0.36 10.4 1.1 1.8 2 0 0 2 2 2 0 ProQ/FINO family Fis1_TPR_C PF14853.1 KFX86243.1 - 0.25 11.2 3.0 11 5.9 0.0 3.1 3 1 1 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat XPC-binding PF09280.6 KFX86243.1 - 0.44 10.0 4.3 5 6.6 1.7 3.3 2 2 2 4 4 4 0 XPC-binding domain DUF536 PF04394.9 KFX86243.1 - 3.3 7.5 7.3 0.12 12.1 0.9 1.7 2 0 0 2 2 1 0 Protein of unknown function, DUF536 Glyco_transf_92 PF01697.22 KFX86245.1 - 4.8e-07 29.3 0.0 6.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 KFX86245.1 - 0.0014 18.8 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycoprotein_G PF00802.14 KFX86253.1 - 3.9 6.5 9.3 4.2 6.4 6.5 1.0 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF2360 PF10152.4 KFX86253.1 - 5.5 7.2 13.1 6.4 7.0 9.1 1.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) UPF0020 PF01170.13 KFX86254.1 - 5.1e-06 26.1 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFX86254.1 - 0.0052 16.8 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TatD_DNase PF01026.16 KFX86262.1 - 6.6e-34 117.2 0.0 1e-33 116.6 0.0 1.2 1 1 0 1 1 1 1 TatD related DNase Herpes_BLRF2 PF05812.7 KFX86263.1 - 0.0062 16.3 0.4 0.0064 16.3 0.3 1.2 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein TSC22 PF01166.13 KFX86263.1 - 0.035 14.0 0.1 0.042 13.8 0.0 1.3 1 1 0 1 1 1 0 TSC-22/dip/bun family Allexi_40kDa PF05549.6 KFX86266.1 - 0.076 12.2 0.4 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein CFEM PF05730.6 KFX86268.1 - 2.5e-11 43.2 14.0 3.8e-11 42.6 9.7 1.3 1 0 0 1 1 1 1 CFEM domain DUF780 PF05611.6 KFX86271.1 - 0.021 15.5 5.0 0.031 14.9 3.5 1.4 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) RCR PF12273.3 KFX86271.1 - 3.9 8.0 9.2 4.5 7.8 6.4 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red WD40 PF00400.27 KFX86277.1 - 2.2e-05 24.1 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat Pex14_N PF04695.8 KFX86280.1 - 2.1e-39 134.7 0.2 5e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 KFX86280.1 - 0.0009 16.7 7.7 0.0012 16.3 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Lebercilin PF15619.1 KFX86280.1 - 0.0031 16.9 5.2 0.0047 16.3 3.6 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease WD40_alt PF14077.1 KFX86280.1 - 0.015 14.9 0.5 0.052 13.1 0.1 2.0 1 1 1 2 2 2 0 Alternative WD40 repeat motif PEP-utilisers_N PF05524.8 KFX86280.1 - 0.041 13.6 4.0 1.6 8.5 1.0 3.0 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal CENP-Q PF13094.1 KFX86280.1 - 0.045 13.7 8.5 0.098 12.6 5.9 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Gly_kinase PF02595.10 KFX86280.1 - 0.065 11.9 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family IncA PF04156.9 KFX86280.1 - 0.087 12.4 3.6 0.032 13.8 0.7 1.6 2 0 0 2 2 2 0 IncA protein DUF1542 PF07564.6 KFX86280.1 - 0.56 10.2 4.0 0.66 10.0 0.0 2.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1542) ADIP PF11559.3 KFX86280.1 - 0.73 9.7 6.2 1.4 8.7 4.3 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.6 KFX86280.1 - 0.76 10.2 4.0 1 9.7 2.1 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 KFX86280.1 - 2.5 8.2 14.1 0.51 10.5 5.8 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Methyltransf_26 PF13659.1 KFX86283.1 - 7e-15 55.0 0.0 1.9e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86283.1 - 8.8e-11 42.3 0.0 1.3e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86283.1 - 7.1e-10 38.6 0.0 1.6e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX86283.1 - 5.7e-07 29.8 0.0 9.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX86283.1 - 2.2e-06 27.1 0.0 3.9e-05 23.0 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_10 PF05971.7 KFX86283.1 - 0.00025 20.3 0.0 0.00097 18.3 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 KFX86283.1 - 0.00044 20.6 0.0 0.00082 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 KFX86283.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.7 KFX86283.1 - 0.0029 18.0 0.0 0.013 15.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX86283.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX86283.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFX86283.1 - 0.044 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_tran_28_C PF04101.11 KFX86290.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFX86290.1 - 0.0065 15.6 0.0 0.0089 15.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 CDC14 PF08045.6 KFX86292.1 - 8.3e-46 156.2 0.0 9.3e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component 7TMR-DISMED2 PF07696.6 KFX86293.1 - 0.035 13.5 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 FAD_binding_6 PF00970.19 KFX86296.1 - 8.9e-07 28.9 0.0 0.0065 16.5 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFX86296.1 - 0.00036 21.0 0.0 0.00063 20.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFX86296.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain ECH PF00378.15 KFX86300.1 - 2.4e-13 49.7 0.0 2.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFX86300.1 - 8e-05 22.4 0.0 0.58 9.9 0.0 2.5 2 1 0 2 2 2 2 Peptidase family S49 eIF3_subunit PF08597.5 KFX86300.1 - 0.01 15.3 2.3 0.014 14.9 1.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spectrin PF00435.16 KFX86300.1 - 0.12 12.7 3.0 2.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Spectrin repeat Hydrolase_like PF13242.1 KFX86302.1 - 2.2e-11 43.2 0.0 4.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like RRM_1 PF00076.17 KFX86311.1 - 2.6e-39 132.6 0.3 7.3e-19 67.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX86311.1 - 1.5e-27 95.3 0.1 2e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86311.1 - 2.7e-15 55.9 0.0 1.6e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFX86311.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3602 PF12223.3 KFX86314.1 - 1.5e-08 34.9 19.2 0.0027 18.0 2.8 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Abhydrolase_6 PF12697.2 KFX86315.1 - 2.9e-05 24.0 0.2 4.7e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX86315.1 - 0.0028 17.2 0.0 0.0034 16.9 0.0 1.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chloroplast_duf PF14476.1 KFX86315.1 - 0.15 10.8 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Petal formation-expressed NAD_binding_11 PF14833.1 KFX86317.1 - 5.7e-33 113.5 0.0 8.4e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KFX86317.1 - 1.6e-22 80.0 0.1 2.4e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M23 PF01551.17 KFX86329.1 - 0.096 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M23 CLASP_N PF12348.3 KFX86333.1 - 0.0019 17.6 0.0 0.0021 17.4 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal IBN_N PF03810.14 KFX86333.1 - 0.099 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain HATPase_c PF02518.21 KFX86336.1 - 2.8e-17 62.4 0.0 9e-16 57.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 KFX86336.1 - 0.0021 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_2 PF13581.1 KFX86336.1 - 0.038 13.7 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 KFX86336.1 - 0.038 13.6 0.0 0.092 12.3 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Exo_endo_phos PF03372.18 KFX86338.1 - 0.00051 20.0 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4117 PF13491.1 KFX86338.1 - 0.0025 17.2 9.4 0.13 11.6 1.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4117) DUF1771 PF08590.5 KFX86341.1 - 4.4e-17 61.8 10.3 7.9e-17 61.0 7.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KFX86341.1 - 1.9e-16 60.0 0.1 4.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Smr domain Helicase_C PF00271.26 KFX86342.1 - 1.8e-13 50.1 0.1 3.2e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFX86342.1 - 0.0007 18.5 0.1 0.0068 15.2 0.1 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 TK PF00265.13 KFX86342.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase DUF1275 PF06912.6 KFX86343.1 - 0.00014 21.1 1.8 0.00019 20.6 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) MTP18 PF10558.4 KFX86343.1 - 0.1 12.4 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) MFS_2 PF13347.1 KFX86343.1 - 0.11 10.9 7.9 0.14 10.5 5.5 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Tbf5 PF06331.7 KFX86346.1 - 9.9e-26 89.3 0.3 1.1e-25 89.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 SPO22 PF08631.5 KFX86348.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.4 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like MIP-T3 PF10243.4 KFX86350.1 - 0.024 13.1 11.4 0.029 12.8 7.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4637 PF15470.1 KFX86350.1 - 1.1 8.8 8.4 2.1 7.9 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pkinase PF00069.20 KFX86353.1 - 5.4e-39 133.9 0.0 7.7e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86353.1 - 4.5e-26 91.4 0.0 6.9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX86353.1 - 5.2e-06 25.6 0.0 7.3e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFX86353.1 - 0.062 12.1 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Secretin_N PF03958.12 KFX86353.1 - 0.092 12.9 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain CheX PF13690.1 KFX86355.1 - 0.038 13.8 0.1 0.044 13.6 0.1 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX DTHCT PF08070.6 KFX86355.1 - 0.045 14.4 2.2 0.049 14.2 1.5 1.0 1 0 0 1 1 1 0 DTHCT (NUC029) region BRX PF08381.6 KFX86366.1 - 0.14 11.2 0.3 0.23 10.5 0.2 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 BRCA2 PF00634.13 KFX86368.1 - 0.14 11.4 0.2 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 BRCA2 repeat HEXIM PF15313.1 KFX86371.1 - 0.28 11.3 1.4 0.37 10.9 1.0 1.2 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DUF2217 PF10265.4 KFX86372.1 - 0.2 10.4 0.8 0.25 10.0 0.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DEADboxA PF12343.3 KFX86372.1 - 0.86 9.9 9.2 1.5 9.1 6.4 1.5 1 0 0 1 1 1 0 Cold shock protein DEAD box A RRM_6 PF14259.1 KFX86382.1 - 6.4e-08 32.4 0.0 9.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX86382.1 - 7.5e-08 31.8 0.0 9.9e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86382.1 - 5.8e-05 22.8 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX86382.1 - 0.031 14.1 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif API5 PF05918.6 KFX86382.1 - 3.8 5.8 6.3 4.1 5.7 4.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GRP PF07172.6 KFX86382.1 - 5.5 7.5 15.5 8.7 6.9 10.8 1.4 1 0 0 1 1 1 0 Glycine rich protein family SDA1 PF05285.7 KFX86386.1 - 0.24 10.6 14.5 0.29 10.3 10.0 1.1 1 0 0 1 1 1 0 SDA1 Sec39 PF08314.6 KFX86391.1 - 4e-12 44.9 0.8 4.8e-12 44.6 0.5 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Cytadhesin_P30 PF07271.6 KFX86400.1 - 5.3 6.2 8.4 6.8 5.8 5.8 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 adh_short_C2 PF13561.1 KFX86403.1 - 2.5e-18 66.7 0.1 2.8e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX86403.1 - 3.4e-09 36.8 0.2 4.4e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF2360 PF10152.4 KFX86412.1 - 1.4 9.2 5.0 1.6 9.0 3.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 KFX86412.1 - 5.4 6.3 12.9 5.8 6.2 9.0 1.1 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 KFX86412.1 - 6.1 6.1 14.2 10 5.3 9.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-HIT PF04438.11 KFX86413.1 - 6.3e-10 38.5 10.1 8.9e-10 38.0 7.0 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KFX86413.1 - 0.0031 17.3 9.5 0.0049 16.7 6.6 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.19 KFX86413.1 - 0.023 14.5 6.0 0.037 13.9 4.1 1.2 1 0 0 1 1 1 0 B-box zinc finger ArfGap PF01412.13 KFX86413.1 - 0.13 12.0 1.7 0.21 11.3 1.2 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Tnp_zf-ribbon_2 PF13842.1 KFX86413.1 - 0.75 10.2 9.1 1.2 9.6 6.3 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Aldedh PF00171.17 KFX86422.1 - 5.5e-18 64.5 0.1 5.9e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3071 PF11268.3 KFX86422.1 - 0.014 15.1 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) Bromo_TP PF07524.8 KFX86422.1 - 0.15 11.8 0.1 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 Bromodomain associated SRF-TF PF00319.13 KFX86422.1 - 0.16 11.2 0.6 1.4 8.1 0.2 2.2 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Peptidase_C48 PF02902.14 KFX86425.1 - 1.7e-06 27.8 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.12 KFX86427.1 - 0.00038 19.8 0.5 0.00066 19.0 0.3 1.3 1 0 0 1 1 1 1 SWIM zinc finger DnaJ PF00226.26 KFX86430.1 - 5.5e-29 99.6 3.1 6.2e-29 99.5 2.2 1.0 1 0 0 1 1 1 1 DnaJ domain RNA_pol_Rpc82 PF05645.8 KFX86430.1 - 0.051 13.0 0.5 0.058 12.9 0.3 1.0 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 Sigma70_ner PF04546.8 KFX86430.1 - 0.1 12.1 0.5 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DegS PF05384.6 KFX86430.1 - 0.25 10.5 1.0 0.71 9.0 0.7 1.6 1 1 0 1 1 1 0 Sensor protein DegS MULE PF10551.4 KFX86450.1 - 2.3e-16 59.7 0.8 1.7e-15 56.9 0.4 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 KFX86450.1 - 7.2e-05 21.5 0.1 9.7e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Myc_N PF01056.13 KFX86452.1 - 0.0055 15.9 6.2 0.046 12.8 0.5 2.1 2 0 0 2 2 2 2 Myc amino-terminal region YL1 PF05764.8 KFX86452.1 - 0.034 13.7 9.5 0.042 13.4 0.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein LZ_Tnp_IS66 PF13007.2 KFX86452.1 - 0.053 14.1 1.5 0.053 14.1 1.0 2.7 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain Nucleoplasmin PF03066.10 KFX86452.1 - 0.17 11.3 11.2 1.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 KFX86452.1 - 2.4 5.9 15.1 2 6.2 1.1 2.0 2 0 0 2 2 2 0 Nop14-like family DUF3602 PF12223.3 KFX86454.1 - 8.6e-13 48.4 10.7 2.4e-09 37.4 4.3 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF4614 PF15391.1 KFX86454.1 - 0.1 12.3 3.6 0.12 12.1 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Period_C PF12114.3 KFX86454.1 - 3 7.4 8.8 3.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Dsh_C PF12316.3 KFX86454.1 - 4.2 7.4 17.1 6.4 6.8 11.8 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Condensation PF00668.15 KFX86457.1 - 1e-16 60.6 0.0 2.9e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 Condensation domain Pkinase PF00069.20 KFX86467.1 - 2.3e-51 174.4 0.0 2.5e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86467.1 - 1.8e-18 66.5 0.0 3e-18 65.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX86467.1 - 1.4e-07 31.5 1.0 0.0011 18.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFX86467.1 - 1e-06 27.9 0.0 2.9e-06 26.4 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFX86467.1 - 3.3e-05 23.0 0.1 4.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX86467.1 - 0.0046 16.3 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family NIF PF03031.13 KFX86470.1 - 3.9e-07 29.8 0.0 4.2e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNase_T PF00929.19 KFX86474.1 - 9.7e-07 29.2 0.0 1.2e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Metallophos_C PF14008.1 KFX86474.1 - 0.074 13.1 0.0 22 5.2 0.0 2.6 3 0 0 3 3 3 0 Iron/zinc purple acid phosphatase-like protein C DUF2140 PF09911.4 KFX86482.1 - 0.11 11.7 0.2 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) VirE2 PF07229.7 KFX86487.1 - 0.49 8.7 9.0 0.51 8.6 6.2 1.0 1 0 0 1 1 1 0 VirE2 Prothymosin PF03247.9 KFX86487.1 - 0.88 9.7 12.4 2.6 8.2 8.6 1.6 1 1 0 1 1 1 0 Prothymosin/parathymosin family Pox_Ag35 PF03286.9 KFX86487.1 - 1.4 8.4 10.9 1.6 8.2 7.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Adap_comp_sub PF00928.16 KFX86488.1 - 2.8e-05 23.3 0.0 3e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PAT1 PF09770.4 KFX86492.1 - 0.34 9.0 18.9 0.35 9.0 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KFX86492.1 - 0.96 9.2 16.7 1.1 9.1 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C4H2 PF10146.4 KFX86492.1 - 1.8 8.5 9.2 2.5 8.0 6.4 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Suf PF05843.9 KFX86492.1 - 2.1 8.0 6.8 2.8 7.5 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2418 PF10332.4 KFX86493.1 - 0.039 14.2 0.3 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF1212 PF06738.7 KFX86495.1 - 0.053 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Trehalase PF01204.13 KFX86497.1 - 5e-49 167.3 0.1 5.9e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Trehalase Acyl-CoA_dh_C PF12806.2 KFX86497.1 - 0.32 10.8 2.9 0.42 10.4 1.7 1.4 1 1 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like CAF1 PF04857.15 KFX86498.1 - 5.7e-49 166.7 0.0 6.4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 KFX86498.1 - 0.018 15.1 0.0 0.049 13.7 0.0 1.7 2 0 0 2 2 2 0 RFX DNA-binding domain Nop14 PF04147.7 KFX86499.1 - 0.37 8.6 9.9 0.4 8.5 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family Dus PF01207.12 KFX86505.1 - 0.075 11.8 0.1 0.091 11.5 0.1 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Mucin PF01456.12 KFX86505.1 - 0.082 12.6 2.0 0.11 12.2 1.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Mob_synth_C PF06463.8 KFX86507.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C bZIP_1 PF00170.16 KFX86508.1 - 1.8e-05 24.6 7.0 2.3e-05 24.2 4.9 1.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX86508.1 - 0.00034 20.3 6.9 0.00044 20.0 4.8 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFX86508.1 - 0.0023 18.1 1.2 0.0031 17.7 0.8 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor SEEEED PF14797.1 KFX86508.1 - 0.17 12.0 1.6 0.22 11.6 1.1 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex RhoGAP PF00620.22 KFX86509.1 - 8.3e-39 132.6 0.0 9.1e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 RhoGAP domain DUF3710 PF12502.3 KFX86517.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) FumaraseC_C PF10415.4 KFX86524.1 - 2e-24 85.4 0.0 2.3e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Fumarase C C-terminus zf-MIZ PF02891.15 KFX86532.1 - 7.6e-12 44.5 0.3 1.3e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFX86532.1 - 0.0063 16.0 0.5 0.02 14.4 0.3 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rubredoxin PF00301.15 KFX86532.1 - 0.21 11.4 2.6 0.44 10.4 1.8 1.5 1 0 0 1 1 1 0 Rubredoxin Pkinase PF00069.20 KFX86537.1 - 0.00042 19.5 0.0 0.00098 18.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86537.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase DHquinase_II PF01220.14 KFX86537.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Dehydroquinase class II RNase_PH PF01138.16 KFX86538.1 - 0.062 13.6 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 RCR PF12273.3 KFX86540.1 - 9.3e-13 48.8 18.8 1.2e-12 48.4 13.0 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PV-1 PF06637.6 KFX86543.1 - 0.0015 17.1 8.6 0.002 16.7 6.0 1.1 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF87 PF01935.12 KFX86543.1 - 0.0026 17.6 4.6 0.0027 17.5 3.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF87 DUF342 PF03961.8 KFX86543.1 - 0.0042 15.5 10.8 0.0033 15.8 3.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 KFX86543.1 - 0.006 16.5 16.7 0.021 14.8 7.1 2.3 1 1 1 2 2 2 1 Seryl-tRNA synthetase N-terminal domain GlcNAc_2-epim PF07221.6 KFX86543.1 - 0.019 14.0 2.7 0.022 13.7 1.8 1.1 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Pox_A_type_inc PF04508.7 KFX86543.1 - 0.024 14.3 1.8 2.7 8.0 0.2 3.5 2 1 1 3 3 2 0 Viral A-type inclusion protein repeat PEARLI-4 PF05278.7 KFX86543.1 - 0.025 13.9 4.7 0.035 13.4 3.3 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc7 PF08317.6 KFX86543.1 - 0.026 13.1 16.0 0.034 12.7 11.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KFX86543.1 - 0.031 12.1 10.8 0.04 11.7 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pal1 PF08316.6 KFX86543.1 - 0.039 14.4 1.7 0.06 13.7 1.2 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein FlxA PF14282.1 KFX86543.1 - 0.06 13.3 24.4 0.11 12.4 1.6 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF4140 PF13600.1 KFX86543.1 - 0.08 13.3 16.3 1.1 9.7 3.9 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3829 PF12889.2 KFX86543.1 - 0.12 11.5 11.2 0.19 10.8 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF3482 PF11981.3 KFX86543.1 - 0.21 10.7 10.1 0.23 10.6 6.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Snf7 PF03357.16 KFX86543.1 - 0.24 10.7 18.8 0.11 11.9 9.5 2.2 1 1 0 1 1 1 0 Snf7 APG6 PF04111.7 KFX86543.1 - 0.29 10.1 15.3 0.42 9.6 10.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KFX86543.1 - 0.41 10.3 23.9 0.69 9.6 16.3 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 KFX86543.1 - 0.45 10.9 14.7 0.12 12.7 3.3 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 KFX86543.1 - 0.53 9.4 6.1 0.77 8.8 4.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 KFX86543.1 - 0.58 9.0 12.8 0.79 8.6 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sulfatase_C PF14707.1 KFX86543.1 - 0.62 10.3 3.3 0.95 9.7 1.9 1.7 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase zf-CpG_bind_C PF12269.3 KFX86543.1 - 0.64 9.4 8.8 0.88 8.9 6.1 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Mnd1 PF03962.10 KFX86543.1 - 0.66 9.6 17.6 0.056 13.1 6.8 2.0 1 1 1 2 2 2 0 Mnd1 family TBPIP PF07106.8 KFX86543.1 - 0.71 9.3 17.3 0.52 9.8 7.8 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Med9 PF07544.8 KFX86543.1 - 0.79 9.4 11.9 0.23 11.2 4.1 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HlyD PF00529.15 KFX86543.1 - 1.1 8.5 17.3 1.5 8.0 12.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF489 PF04356.7 KFX86543.1 - 1.1 8.7 7.3 3.7 7.0 0.8 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF489) DUF1640 PF07798.6 KFX86543.1 - 1.2 9.1 12.3 15 5.5 8.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) FUSC PF04632.7 KFX86543.1 - 1.6 7.0 6.6 1.8 6.9 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ycf1 PF05758.7 KFX86543.1 - 2 6.0 8.5 2.4 5.7 5.9 1.0 1 0 0 1 1 1 0 Ycf1 UPF0184 PF03670.8 KFX86543.1 - 2.2 8.5 10.9 0.33 11.1 3.4 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) ApoO PF09769.4 KFX86543.1 - 2.2 7.9 4.3 10 5.8 3.0 1.9 1 1 0 1 1 1 0 Apolipoprotein O Ax_dynein_light PF10211.4 KFX86543.1 - 2.9 7.6 17.8 3.1 7.5 6.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Jnk-SapK_ap_N PF09744.4 KFX86543.1 - 2.9 7.8 12.5 5 7.0 8.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Allexi_40kDa PF05549.6 KFX86543.1 - 3.1 7.0 10.6 5.9 6.1 7.0 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein DivIC PF04977.10 KFX86543.1 - 3.2 7.3 20.5 2.2 7.8 0.8 3.3 1 1 2 3 3 3 0 Septum formation initiator DUF724 PF05266.9 KFX86543.1 - 4.3 6.9 15.5 5.8 6.4 10.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.15 KFX86543.1 - 4.4 7.1 20.2 6 6.6 2.2 3.3 1 1 2 3 3 3 0 Prefoldin subunit COG2 PF06148.6 KFX86543.1 - 5 7.0 12.6 3 7.7 2.8 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.5 KFX86543.1 - 5.4 7.1 14.0 12 6.0 9.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.4 KFX86543.1 - 6.3 5.1 15.5 12 4.2 10.7 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-ZPR1 PF03367.8 KFX86543.1 - 6.4 5.9 6.5 11 5.0 4.4 1.6 1 1 0 1 1 1 0 ZPR1 zinc-finger domain DUF4200 PF13863.1 KFX86543.1 - 6.9 6.6 18.3 11 6.0 12.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) V-SNARE PF05008.10 KFX86543.1 - 8 6.7 16.3 32 4.7 9.7 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus YlqD PF11068.3 KFX86543.1 - 9.4 6.2 17.7 0.93 9.5 4.3 2.2 1 1 1 2 2 2 0 YlqD protein YihI PF04220.7 KFX86553.1 - 0.062 12.6 1.1 0.076 12.3 0.8 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Sugar_tr PF00083.19 KFX86555.1 - 0.00062 18.4 1.1 0.00071 18.2 0.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter YjbE PF11106.3 KFX86555.1 - 1.1 9.2 7.2 1.8 8.5 4.9 1.4 1 1 0 1 1 1 0 Exopolysaccharide production protein YjbE Terminase_6 PF03237.10 KFX86567.1 - 0.023 13.4 0.2 0.025 13.3 0.1 1.1 1 0 0 1 1 1 0 Terminase-like family Striatin PF08232.7 KFX86567.1 - 0.03 14.6 0.3 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 Striatin family XhlA PF10779.4 KFX86567.1 - 0.74 9.7 4.1 1.3 8.9 2.9 1.3 1 0 0 1 1 1 0 Haemolysin XhlA NAD_binding_6 PF08030.7 KFX86573.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX86573.1 - 0.06 13.2 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD-binding domain PAT1 PF09770.4 KFX86575.1 - 2.5 6.2 18.6 2.5 6.2 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VWA_3 PF13768.1 KFX86579.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFX86579.1 - 0.0046 17.0 0.0 0.0058 16.7 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1147 PF06615.6 KFX86579.1 - 0.0094 15.7 0.2 0.015 15.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1147) DUF3435 PF11917.3 KFX86589.1 - 1.5e-13 50.2 0.3 1.8e-13 50.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CobU PF02283.11 KFX86597.1 - 0.064 12.6 0.1 0.084 12.2 0.1 1.1 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Cupin_1 PF00190.17 KFX86607.1 - 7e-07 28.7 0.1 8.5e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Cupin tify PF06200.9 KFX86607.1 - 0.0026 16.9 0.1 0.0059 15.8 0.0 1.6 1 0 0 1 1 1 1 tify domain Apc4 PF12896.2 KFX86612.1 - 2.7e-29 101.9 0.0 2.9e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF3435 PF11917.3 KFX86613.1 - 8.1e-08 31.3 0.1 9.2e-08 31.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF4266 PF14086.1 KFX86615.1 - 0.043 14.3 1.9 0.12 12.9 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4266) Abhydrolase_6 PF12697.2 KFX86618.1 - 9.7e-11 41.9 1.3 1.4e-10 41.4 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX86618.1 - 1.3e-07 31.4 0.1 2.1e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFX86618.1 - 0.00049 19.7 0.4 0.00075 19.1 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFX86618.1 - 0.0028 17.2 0.1 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFX86618.1 - 0.029 14.2 0.1 0.079 12.8 0.1 1.8 1 1 0 1 1 1 0 Putative lysophospholipase Skp1_POZ PF03931.10 KFX86619.1 - 1.5e-10 41.0 0.3 3.3e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.14 KFX86619.1 - 5.8e-09 35.8 0.4 1.4e-08 34.5 0.2 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain F-box PF00646.28 KFX86619.1 - 0.079 12.6 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 F-box domain Corona_nucleoca PF00937.13 KFX86620.1 - 1.1 8.1 6.8 2 7.2 4.7 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NAM-associated PF14303.1 KFX86620.1 - 9.8 6.4 9.4 12 6.1 5.9 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Ank_2 PF12796.2 KFX86621.1 - 2.2e-27 95.2 2.3 6.2e-15 55.3 0.0 4.0 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX86621.1 - 4.1e-21 73.6 0.2 2.2e-06 27.2 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 KFX86621.1 - 2e-16 58.4 0.3 0.00024 21.0 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KFX86621.1 - 6.7e-14 51.9 0.0 1.4e-07 31.8 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX86621.1 - 1.2e-12 47.6 1.7 3.5e-05 23.8 0.0 5.2 4 2 2 6 6 6 3 Ankyrin repeats (many copies) F-box PF00646.28 KFX86621.1 - 0.0075 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX86621.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.2 KFX86622.1 - 1.1e-30 105.7 3.8 2.9e-22 78.8 0.8 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX86622.1 - 1.4e-26 92.3 5.9 1.7e-07 31.5 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFX86622.1 - 1.5e-26 90.8 12.6 3.2e-08 32.9 0.2 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFX86622.1 - 7e-25 86.4 13.2 3.3e-09 36.6 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX86622.1 - 2.2e-21 73.7 3.1 1.4e-05 24.8 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat DUF3459 PF11941.3 KFX86622.1 - 0.034 14.2 0.1 2.4 8.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3459) Iso_dh PF00180.15 KFX86624.1 - 3.5e-101 338.6 0.0 4.3e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KFX86624.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.1 KFX86625.1 - 1.9e-37 128.7 0.0 9e-37 126.5 0.0 2.2 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 KFX86625.1 - 1e-05 25.2 0.2 5.4e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Vps51/Vps67 MIF4G PF02854.14 KFX86626.1 - 5.3e-63 212.2 0.1 2.7e-28 98.8 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KFX86626.1 - 5.7e-56 188.9 10.7 5.7e-56 188.9 7.4 3.3 4 0 0 4 4 4 2 Up-frameshift suppressor 2 Ion_trans_2 PF07885.11 KFX86627.1 - 1e-30 105.2 26.3 1.4e-17 63.1 3.7 3.2 3 0 0 3 3 3 2 Ion channel DUF3671 PF12420.3 KFX86627.1 - 4.5 7.3 5.6 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function GATA PF00320.22 KFX86628.1 - 2.5e-14 52.2 2.4 5.3e-14 51.2 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DivIVA PF05103.8 KFX86628.1 - 0.084 12.9 7.4 0.13 12.3 5.2 1.2 1 0 0 1 1 1 0 DivIVA protein CENP-F_leu_zip PF10473.4 KFX86628.1 - 0.089 12.6 11.7 2.5 7.9 0.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 KFX86628.1 - 0.12 11.6 7.7 0.17 11.1 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.4 KFX86628.1 - 0.38 9.6 7.0 0.65 8.8 4.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SpecificRecomb PF10136.4 KFX86628.1 - 0.48 8.3 1.6 0.73 7.8 1.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Fmp27_WPPW PF10359.4 KFX86628.1 - 0.81 8.0 6.0 1.2 7.5 4.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Phlebovirus_NSM PF07246.6 KFX86628.1 - 0.95 8.5 4.3 1.5 7.9 3.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IncA PF04156.9 KFX86628.1 - 1.1 8.7 8.1 1.9 8.0 5.6 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFX86628.1 - 1.4 7.9 6.8 2.4 7.1 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 KFX86628.1 - 3.1 7.3 9.5 1.9 8.0 2.9 2.2 2 0 0 2 2 2 0 Septum formation initiator PI3_PI4_kinase PF00454.22 KFX86629.1 - 8.2e-36 123.6 0.0 1.2e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 KFX86630.1 - 1.4e-67 227.6 0.0 2.5e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX86630.1 - 1.3e-10 40.9 0.0 3.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX86630.1 - 6.3e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KFX86630.1 - 1.4e-05 24.6 5.7 2.9e-05 23.6 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX86630.1 - 0.0048 16.5 5.8 0.014 15.0 4.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX86630.1 - 0.0049 16.5 8.6 0.017 14.8 5.9 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX86630.1 - 0.0083 16.1 3.2 0.021 14.8 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX86630.1 - 0.031 14.0 3.3 0.073 12.9 2.3 1.7 1 0 0 1 1 1 0 Ring finger domain AftA_N PF12250.3 KFX86630.1 - 0.052 12.2 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal RNA_pol_I_TF PF04090.7 KFX86631.1 - 8.8e-07 28.3 0.0 8.2e-05 21.9 0.0 2.3 2 1 0 2 2 2 2 RNA polymerase I specific initiation factor WD40 PF00400.27 KFX86632.1 - 1e-18 66.4 12.6 4.3e-06 26.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFX86632.1 - 0.022 14.4 2.0 0.17 11.5 0.1 2.8 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term RBDV_coat PF06593.6 KFX86632.1 - 0.034 13.3 0.1 0.052 12.7 0.1 1.3 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein DEAD PF00270.24 KFX86633.1 - 6.5e-25 87.5 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Yip1 PF04893.12 KFX86633.1 - 8.9e-14 51.3 8.8 1.8e-13 50.3 6.1 1.5 1 0 0 1 1 1 1 Yip1 domain DUF1998 PF09369.5 KFX86633.1 - 4.4e-13 49.6 0.2 1.2e-12 48.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Ran_BP1 PF00638.13 KFX86633.1 - 1.3e-12 47.7 0.1 1.8e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain Helicase_C PF00271.26 KFX86633.1 - 4.7e-10 39.2 0.1 1.7e-09 37.4 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 KFX86633.1 - 0.00075 19.4 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF1282 PF06930.7 KFX86633.1 - 0.47 10.1 4.1 0.9 9.1 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) RRM_6 PF14259.1 KFX86634.1 - 0.093 12.7 0.0 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Na_Ca_ex PF01699.19 KFX86635.1 - 1.3e-26 92.9 26.1 8.7e-16 57.7 5.8 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Mob1_phocein PF03637.12 KFX86636.1 - 6.2e-24 84.6 0.1 1e-23 83.9 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 KFX86637.1 - 3.6e-43 147.0 0.5 5.9e-43 146.3 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.13 KFX86637.1 - 1.2e-31 109.3 1.0 1.2e-31 109.3 0.7 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CobW_C PF07683.9 KFX86637.1 - 0.0014 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 KFX86637.1 - 0.0061 16.7 0.2 0.35 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFX86637.1 - 0.0087 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KFX86637.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 KFX86637.1 - 0.02 14.4 0.3 0.052 13.0 0.2 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFX86637.1 - 0.028 13.8 1.5 0.5 9.7 1.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFX86637.1 - 0.052 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 KFX86637.1 - 0.072 11.8 0.4 3.9 6.1 0.0 2.4 3 0 0 3 3 3 0 ArgK protein Septin PF00735.13 KFX86637.1 - 0.082 11.9 0.3 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.18 KFX86637.1 - 0.12 12.3 0.2 0.3 11.0 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KFX86637.1 - 0.13 12.5 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.1 KFX86641.1 - 3.8e-19 68.9 0.0 6.3e-19 68.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86641.1 - 2.8e-14 52.9 0.1 8e-13 48.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX86641.1 - 1.3e-12 48.0 0.0 2.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86641.1 - 1.1e-11 45.2 0.1 1.6e-10 41.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX86641.1 - 5.1e-11 42.9 0.0 6e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX86641.1 - 6.4e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX86641.1 - 0.00011 21.2 0.0 0.00027 20.0 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFX86641.1 - 0.00017 21.5 0.0 0.00071 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX86641.1 - 0.00081 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFX86641.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KFX86641.1 - 0.0019 17.3 0.0 0.0035 16.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFX86641.1 - 0.0028 16.8 0.0 0.069 12.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KFX86641.1 - 0.0034 16.8 0.0 0.0088 15.5 0.0 1.8 2 1 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KFX86641.1 - 0.0054 15.8 0.0 0.029 13.4 0.0 2.2 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 KFX86641.1 - 0.035 13.2 0.0 8 5.5 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB DUF3489 PF11994.3 KFX86641.1 - 0.038 13.9 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Methyltransf_2 PF00891.13 KFX86642.1 - 5.6e-22 78.1 0.0 8.9e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KFX86642.1 - 0.0023 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Asp PF00026.18 KFX86643.1 - 2.4e-65 220.8 3.8 3e-65 220.5 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX86643.1 - 2.3e-07 30.9 0.0 8.1e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX86643.1 - 1.7e-05 25.1 0.7 0.045 14.2 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease Glyoxalase_2 PF12681.2 KFX86644.1 - 5.6e-12 46.2 0.1 7.7e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFX86644.1 - 5.3e-06 26.4 0.0 8.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Esterase_phd PF10503.4 KFX86645.1 - 2.4e-20 72.7 0.1 4e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX86645.1 - 2.6e-09 36.6 0.6 4.2e-09 35.9 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX86645.1 - 0.00015 21.5 0.1 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX86645.1 - 0.0068 15.9 0.1 0.0091 15.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold UCR_Fe-S_N PF10399.4 KFX86645.1 - 0.044 12.9 0.5 0.082 12.0 0.4 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal YhhN PF07947.9 KFX86646.1 - 7.2e-39 133.0 4.2 1.4e-38 132.1 2.9 1.5 1 1 0 1 1 1 1 YhhN-like protein DHquinase_I PF01487.10 KFX86647.1 - 5.1e-39 134.2 0.0 8.5e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KFX86647.1 - 2.5e-17 63.1 0.5 7.6e-17 61.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KFX86647.1 - 2.1e-16 59.7 0.0 5.5e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFX86647.1 - 1.8e-10 41.0 0.0 4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 KFX86647.1 - 0.051 13.4 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KFX86648.1 - 1.1e-16 60.4 0.1 1.9e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX86648.1 - 4.1e-07 29.8 13.6 7.2e-07 29.0 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.20 KFX86649.1 - 1.2e-72 244.4 0.0 1.3e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 KFX86650.1 - 1.1e-21 76.6 0.0 2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFX86650.1 - 4.2e-14 52.7 0.0 6.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 KFX86650.1 - 0.097 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.19 KFX86651.1 - 1.6e-130 435.7 23.6 1.8e-130 435.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX86651.1 - 6.8e-20 71.0 39.2 3.7e-18 65.3 26.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily PIG-P PF08510.7 KFX86651.1 - 0.034 13.7 0.0 0.12 11.9 0.0 2.1 1 0 0 1 1 1 0 PIG-P AP_endonuc_2 PF01261.19 KFX86652.1 - 1.6e-28 99.4 0.0 3e-28 98.5 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel F-box-like PF12937.2 KFX86653.1 - 0.00031 20.3 0.3 0.0031 17.1 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFX86653.1 - 0.1 12.3 2.0 0.59 9.8 0.3 2.9 2 1 0 2 2 2 0 F-box domain XRCC4 PF06632.7 KFX86655.1 - 0.00011 21.2 20.1 0.00034 19.5 14.0 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PUF PF00806.14 KFX86656.1 - 3.6e-37 123.7 1.9 8e-06 25.0 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 KFX86656.1 - 0.029 14.9 0.1 0.83 10.3 0.0 2.9 3 0 0 3 3 3 0 Regulator of ribonuclease activity B DUF2730 PF10805.3 KFX86656.1 - 0.25 11.0 2.7 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) MRP-S33 PF08293.6 KFX86657.1 - 2.6e-32 110.6 0.6 3.5e-32 110.2 0.1 1.4 1 1 1 2 2 2 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.21 KFX86658.1 - 7.3e-14 52.1 0.1 2.6e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFX86658.1 - 3.9e-10 39.7 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KFX86658.1 - 0.075 13.6 0.0 0.075 13.6 0.0 3.2 3 1 0 3 3 3 0 Double-stranded RNA binding motif Glyco_hydro_43 PF04616.9 KFX86659.1 - 7.7e-72 241.7 0.4 1.3e-71 240.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 4HBT PF03061.17 KFX86659.1 - 2.4e-08 33.9 0.1 4.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF1945 PF09178.5 KFX86659.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) 4HBT_3 PF13622.1 KFX86659.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4176 PF13780.1 KFX86659.1 - 0.087 12.5 1.1 14 5.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) Sugar_tr PF00083.19 KFX86660.1 - 1.1e-73 248.4 22.5 1.3e-73 248.1 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX86660.1 - 5.1e-26 91.2 25.4 1.4e-19 70.0 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX86660.1 - 2.6e-06 25.9 2.3 2.6e-06 25.9 1.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) BC10 PF06726.7 KFX86661.1 - 1.6e-16 60.0 10.6 3e-16 59.1 7.3 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DZF PF07528.9 KFX86662.1 - 0.026 13.9 2.6 0.029 13.7 0.3 2.2 1 1 1 2 2 2 0 DZF domain DUF1664 PF07889.7 KFX86662.1 - 0.22 11.3 7.3 1.7 8.4 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_3 PF13758.1 KFX86663.1 - 5.9e-28 96.5 0.8 1.8e-27 94.9 0.6 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 KFX86663.1 - 9.2e-20 71.3 13.9 5.1e-19 69.0 0.0 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3835) Noelin-1 PF12308.3 KFX86663.1 - 0.033 13.9 0.2 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein FliJ PF02050.11 KFX86663.1 - 0.13 12.2 0.3 0.13 12.2 0.2 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein Spc7 PF08317.6 KFX86663.1 - 0.26 9.8 3.9 0.57 8.7 2.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 KFX86663.1 - 6.8 6.5 14.7 0.78 9.5 0.5 3.9 4 0 0 4 4 4 0 Tropomyosin like MAT1 PF06391.8 KFX86664.1 - 2.7e-28 98.9 16.9 3.5e-28 98.5 11.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 KFX86664.1 - 0.00016 21.2 4.3 0.00033 20.2 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX86664.1 - 0.0026 17.4 5.1 0.0041 16.7 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX86664.1 - 0.0049 16.5 8.3 0.015 15.0 5.8 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX86664.1 - 0.0067 16.4 7.2 0.014 15.4 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX86664.1 - 0.054 13.3 6.8 0.14 11.9 4.7 1.7 1 1 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 KFX86664.1 - 0.39 10.4 4.2 1.1 9.0 2.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KFX86664.1 - 0.54 9.8 4.5 1.5 8.4 1.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HrpA_pilin PF09589.5 KFX86664.1 - 0.69 10.3 4.2 0.76 10.2 1.9 1.7 1 1 0 1 1 1 0 HrpA pilus formation protein zf-C3HC4_4 PF15227.1 KFX86664.1 - 0.97 9.3 4.7 2.6 7.9 3.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Astro_capsid PF03115.9 KFX86664.1 - 1.2 7.2 4.5 1.6 6.9 3.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF4192 PF13830.1 KFX86664.1 - 1.7 8.2 11.4 3 7.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CS PF04969.11 KFX86665.1 - 1.1e-14 54.6 0.2 3.7e-14 53.0 0.0 2.0 2 1 0 2 2 2 1 CS domain SnoaL_4 PF13577.1 KFX86667.1 - 6.3e-06 26.1 0.4 9.8e-06 25.4 0.3 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KFX86667.1 - 0.00026 21.0 0.2 0.0012 18.8 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KFX86667.1 - 0.0004 20.7 0.2 0.00057 20.2 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFX86667.1 - 0.0016 18.6 0.5 0.0035 17.5 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) NmrA PF05368.8 KFX86668.1 - 1.2e-32 113.0 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX86668.1 - 4.4e-05 23.5 0.0 0.00011 22.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX86668.1 - 0.005 15.5 0.0 0.01 14.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX86668.1 - 0.12 11.7 0.1 0.28 10.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 KFX86669.1 - 6.5e-18 65.3 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX86669.1 - 0.082 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Mito_fiss_reg PF05308.6 KFX86670.1 - 0.11 11.8 0.4 0.12 11.6 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-RING_5 PF14634.1 KFX86671.1 - 2.8e-05 23.7 0.6 0.00025 20.7 0.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX86671.1 - 0.0062 16.1 1.0 0.014 15.0 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX86671.1 - 0.0085 16.0 1.7 0.019 14.9 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFX86671.1 - 0.018 14.8 1.5 0.13 12.1 0.7 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 KFX86671.1 - 0.035 13.9 1.6 0.074 12.9 0.1 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX86671.1 - 0.038 13.7 0.1 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 KFX86671.1 - 0.066 13.0 1.3 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Ring finger domain Dmrt1 PF12374.3 KFX86671.1 - 4.5 7.6 9.0 7.4 7.0 4.5 2.5 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Cullin_binding PF03556.10 KFX86672.1 - 3e-29 101.5 6.4 4.9e-29 100.8 4.4 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KFX86672.1 - 5.3e-06 25.8 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Ribosomal_S6 PF01250.12 KFX86673.1 - 4.9e-09 35.9 0.0 5.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 RDM PF11002.3 KFX86673.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 RFPL defining motif (RDM) WD40 PF00400.27 KFX86674.1 - 1.7e-24 84.7 9.2 1.2e-10 40.7 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFX86674.1 - 3e-18 65.4 0.0 8.5e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 KFX86674.1 - 0.021 13.5 0.2 0.81 8.3 0.4 2.5 1 1 1 2 2 2 0 Nup133 N terminal like B-block_TFIIIC PF04182.7 KFX86675.1 - 1.3e-13 50.5 0.0 3.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KFX86675.1 - 0.0061 16.2 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 MarR family Hanta_G1 PF01567.11 KFX86675.1 - 7.4 4.6 0.1 12 4.0 0.1 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 M16C_assoc PF08367.6 KFX86678.1 - 2.1e-51 174.2 0.1 2.8e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KFX86678.1 - 3.3e-23 82.3 0.0 3.7e-22 78.8 0.0 2.6 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFX86678.1 - 1.3e-08 34.6 0.1 6.2e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 KFX86679.1 - 6.4e-93 311.2 58.8 8.6e-93 310.7 40.7 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Histone_HNS PF00816.16 KFX86680.1 - 0.038 14.4 1.5 0.11 12.9 1.0 1.8 1 0 0 1 1 1 0 H-NS histone family DUF4120 PF13496.1 KFX86680.1 - 0.17 11.9 0.3 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) NMO PF03060.10 KFX86681.1 - 6.1e-72 242.5 2.7 7e-72 242.3 1.8 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFX86681.1 - 1.7e-05 23.8 0.6 0.00013 21.0 0.1 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFX86681.1 - 0.011 14.5 5.3 0.019 13.8 3.7 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF3173 PF11372.3 KFX86681.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) AAA_assoc_C PF09821.4 KFX86685.1 - 0.013 15.7 0.3 0.013 15.7 0.2 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain CRISPR_Cas2 PF09827.4 KFX86685.1 - 2 8.6 4.8 16 5.7 0.0 3.6 4 0 0 4 4 4 0 CRISPR associated protein Cas2 AAA PF00004.24 KFX86686.1 - 3.7e-21 75.7 0.2 2.5e-20 73.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX86686.1 - 0.00031 20.8 0.4 0.025 14.7 0.0 3.2 3 1 1 4 4 3 1 AAA domain AAA_5 PF07728.9 KFX86686.1 - 0.00047 19.8 0.0 0.0014 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX86686.1 - 0.00092 19.2 2.9 0.0028 17.6 0.6 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KFX86686.1 - 0.003 18.3 0.1 0.023 15.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX86686.1 - 0.0051 16.6 0.1 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFX86686.1 - 0.0085 15.9 0.0 0.088 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX86686.1 - 0.01 16.1 0.0 0.04 14.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX86686.1 - 0.012 15.3 0.1 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KFX86686.1 - 0.017 14.6 0.2 0.092 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 KFX86686.1 - 0.02 14.8 1.4 0.057 13.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFX86686.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KFX86686.1 - 0.024 14.7 0.3 0.46 10.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_25 PF13481.1 KFX86686.1 - 0.086 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 KFX86687.1 - 2.9e-07 30.4 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX86687.1 - 0.00029 20.9 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX86687.1 - 0.0024 17.9 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_N PF08240.7 KFX86688.1 - 1.6e-06 27.8 0.0 1.8e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX86689.1 - 1.8e-13 50.1 0.0 2.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX86689.1 - 1.1e-05 26.3 0.0 1.5e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hyd_65N_2 PF14498.1 KFX86690.1 - 7.7e-50 169.7 0.1 1.2e-49 169.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF608 PF04685.8 KFX86690.1 - 0.00013 20.8 0.0 0.0002 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 PAH PF02671.16 KFX86691.1 - 4.2e-11 42.2 0.2 1.3e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Paired amphipathic helix repeat DASH_Dad3 PF08656.5 KFX86691.1 - 0.092 12.4 1.5 0.22 11.2 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Utp12 PF04003.7 KFX86691.1 - 0.65 9.9 5.3 1 9.2 0.2 2.8 2 1 1 3 3 3 0 Dip2/Utp12 Family Dynamin_N PF00350.18 KFX86692.1 - 2.8e-19 69.5 0.0 7e-19 68.2 0.0 1.7 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFX86692.1 - 8.2e-11 41.2 0.3 1.2e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KFX86692.1 - 7.7e-05 22.5 1.3 0.00032 20.5 0.0 2.7 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX86692.1 - 0.00015 21.6 0.0 0.00095 19.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX86692.1 - 0.0062 15.8 0.0 2.9 7.1 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 KFX86692.1 - 0.03 14.8 0.0 0.09 13.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein MFS_1 PF07690.11 KFX86693.1 - 1.9e-35 122.2 37.7 6e-29 100.8 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX86693.1 - 9.7e-13 47.4 5.5 9.7e-13 47.4 3.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.10 KFX86693.1 - 0.56 8.8 21.2 0.27 9.8 3.6 3.2 2 1 0 3 3 3 0 PUCC protein MatE PF01554.13 KFX86694.1 - 8.7e-50 168.4 23.6 5.4e-28 97.6 2.6 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KFX86694.1 - 7.4e-09 35.5 4.2 7.4e-09 35.5 2.9 4.3 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.16 KFX86695.1 - 1.1e-14 54.3 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family RNase_PH PF01138.16 KFX86696.1 - 5.1e-06 26.8 0.0 7.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SRP-alpha_N PF04086.8 KFX86697.1 - 4.6e-74 249.3 0.0 6.4e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KFX86697.1 - 3.3e-51 173.5 0.1 6e-51 172.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KFX86697.1 - 5.9e-07 29.4 0.1 2.2e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 KFX86697.1 - 1.9e-06 27.4 0.1 4.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KFX86697.1 - 2.5e-06 26.4 0.1 5.9e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 KFX86697.1 - 0.00078 19.4 0.1 0.002 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain MobB PF03205.9 KFX86697.1 - 0.0021 17.7 0.1 0.0047 16.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CinA PF02464.12 KFX86697.1 - 0.013 14.9 1.6 0.013 14.9 0.1 1.8 2 0 0 2 2 2 0 Competence-damaged protein Fer4_NifH PF00142.13 KFX86697.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family cobW PF02492.14 KFX86697.1 - 0.03 13.7 0.2 0.073 12.5 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KFX86697.1 - 0.032 13.8 0.1 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFX86697.1 - 0.033 14.1 0.1 0.11 12.3 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFX86697.1 - 0.043 14.1 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 KFX86697.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NTPase MipZ PF09140.6 KFX86697.1 - 0.053 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_14 PF13173.1 KFX86697.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain YIF1 PF03878.10 KFX86698.1 - 1.7e-78 263.0 2.5 2.1e-78 262.7 1.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KFX86698.1 - 5.6e-05 22.6 6.1 0.00013 21.5 4.2 1.6 1 0 0 1 1 1 1 Yip1 domain AMP-binding PF00501.23 KFX86699.1 - 3.1e-72 243.2 0.0 4e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX86699.1 - 9.6e-10 39.2 0.0 2.5e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.17 KFX86700.1 - 1.1e-122 409.6 0.0 1.4e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.20 KFX86701.1 - 2.5e-06 27.7 0.0 6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GATase_2 PF00310.16 KFX86702.1 - 3.3e-20 72.1 0.0 3.4e-15 55.6 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFX86702.1 - 7.7e-14 51.7 0.0 2.3e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFX86702.1 - 8.6e-13 48.1 0.0 2.1e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KFX86702.1 - 6.1e-12 45.3 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KFX86702.1 - 0.00011 20.9 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 KFX86702.1 - 0.025 14.1 0.1 0.77 9.3 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase TFIIS_C PF01096.13 KFX86703.1 - 8.1e-20 70.1 3.0 8.1e-20 70.1 2.1 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFX86703.1 - 0.018 14.7 0.1 0.018 14.7 0.1 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Dynactin_p62 PF05502.8 KFX86703.1 - 0.084 11.6 0.7 0.086 11.5 0.5 1.2 1 0 0 1 1 1 0 Dynactin p62 family C1_3 PF07649.7 KFX86703.1 - 0.31 11.1 0.4 0.31 11.1 0.3 2.4 3 0 0 3 3 3 0 C1-like domain Zn_Tnp_IS1595 PF12760.2 KFX86703.1 - 5.6 6.8 8.2 5.2 6.9 0.2 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KFX86703.1 - 8 6.5 7.8 4 7.5 0.8 2.9 3 1 0 3 3 3 0 TFIIH C1-like domain Ank_2 PF12796.2 KFX86704.1 - 1.1e-12 48.0 0.1 2.9e-12 46.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX86704.1 - 8.6e-11 41.0 0.0 0.0019 17.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFX86704.1 - 5.2e-09 35.4 0.1 0.013 15.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFX86704.1 - 1.9e-07 31.4 0.1 1.1e-05 25.8 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX86704.1 - 0.0012 19.0 0.1 0.31 11.3 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) rve PF00665.21 KFX86706.1 - 6.8e-20 71.3 0.0 1.2e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KFX86706.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Trypan_PARP PF05887.6 KFX86707.1 - 0.013 15.2 7.3 0.013 15.2 5.1 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) HeLo PF14479.1 KFX86707.1 - 1.5 8.4 7.1 2.6 7.7 2.2 2.2 2 0 0 2 2 2 0 Prion-inhibition and propagation DUF936 PF06075.7 KFX86709.1 - 0.016 14.1 5.3 0.019 13.9 3.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Beta-lactamase PF00144.19 KFX86711.1 - 3.6e-46 157.7 0.1 1.1e-45 156.0 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX86711.1 - 0.0009 18.5 0.0 0.0023 17.2 0.0 1.6 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Glyco_hydro_3 PF00933.16 KFX86712.1 - 1.3e-97 326.4 0.0 2e-97 325.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX86712.1 - 8.2e-58 195.5 3.5 9.2e-58 195.4 0.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX86712.1 - 1.1e-11 44.4 0.0 2.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain AAA PF00004.24 KFX86713.1 - 1.3e-41 141.8 0.0 2.2e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX86713.1 - 5.7e-07 29.7 0.1 0.00022 21.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFX86713.1 - 1.4e-06 28.2 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFX86713.1 - 1e-05 24.6 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFX86713.1 - 2e-05 24.3 0.1 7.1e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX86713.1 - 0.00027 21.0 0.1 0.00093 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFX86713.1 - 0.00029 19.9 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFX86713.1 - 0.0013 18.7 0.8 0.0041 17.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFX86713.1 - 0.0019 17.9 0.2 0.34 10.5 0.1 3.0 2 1 1 3 3 3 1 NACHT domain AAA_14 PF13173.1 KFX86713.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX86713.1 - 0.0027 17.6 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX86713.1 - 0.0043 17.8 0.2 0.012 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFX86713.1 - 0.0054 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFX86713.1 - 0.0065 16.2 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KFX86713.1 - 0.0091 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KFX86713.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFX86713.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFX86713.1 - 0.031 13.4 0.2 0.44 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 KFX86713.1 - 0.035 12.8 1.6 0.046 12.4 0.1 1.8 2 1 0 2 2 2 0 TIP49 C-terminus RNA_helicase PF00910.17 KFX86713.1 - 0.042 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KFX86713.1 - 0.042 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 KFX86713.1 - 0.055 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KFX86713.1 - 0.092 11.9 1.1 0.21 10.7 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFX86713.1 - 0.093 12.2 1.3 0.14 11.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KFX86713.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KFX86713.1 - 0.12 12.6 0.5 0.85 9.9 0.4 2.4 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KFX86713.1 - 0.13 11.6 4.4 0.25 10.7 0.3 2.6 2 1 0 3 3 3 0 AAA domain UQ_con PF00179.21 KFX86714.1 - 2.8e-41 140.2 0.0 4e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KFX86714.1 - 1.1e-07 31.2 0.1 2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RWD PF05773.17 KFX86714.1 - 0.1 12.5 0.1 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 RWD domain Methyltransf_24 PF13578.1 KFX86715.1 - 0.00027 21.7 0.0 0.00077 20.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain SurA_N_3 PF13624.1 KFX86715.1 - 0.12 12.3 0.2 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 SurA N-terminal domain DUF791 PF05631.9 KFX86716.1 - 4.4e-75 252.5 12.0 6.1e-75 252.1 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KFX86716.1 - 1.6e-21 76.3 29.3 1.1e-20 73.6 21.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX86716.1 - 1.3e-08 33.9 7.3 1.3e-08 33.9 5.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFX86716.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.5 2 2 0 2 2 2 0 MFS_1 like family BAR PF03114.13 KFX86717.1 - 7.7e-61 205.5 3.5 9.5e-61 205.2 2.4 1.1 1 0 0 1 1 1 1 BAR domain SCHIP-1 PF10148.4 KFX86717.1 - 0.08 12.3 0.6 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Reo_sigmaC PF04582.7 KFX86718.1 - 0.00071 18.8 27.2 0.14 11.3 0.9 3.6 2 1 0 3 3 3 3 Reovirus sigma C capsid protein DUF948 PF06103.6 KFX86718.1 - 0.1 12.4 12.8 0.12 12.2 0.4 3.8 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) O-antigen_lig PF13425.1 KFX86719.1 - 0.0077 16.2 0.1 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 O-antigen ligase like membrane protein Claudin_2 PF13903.1 KFX86719.1 - 0.01 15.5 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TRIQK PF15168.1 KFX86719.1 - 0.041 13.8 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family ABC_tran_2 PF12848.2 KFX86719.1 - 0.1 12.4 2.7 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF4131 PF13567.1 KFX86719.1 - 0.11 11.9 0.4 0.28 10.5 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) eIF-5a PF01287.15 KFX86720.1 - 1.9e-05 24.4 0.1 6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PRP38 PF03371.10 KFX86721.1 - 8.8e-61 204.5 0.0 1.1e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Fanconi_A PF03511.9 KFX86722.1 - 0.37 10.5 2.0 0.67 9.7 0.2 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein Peptidase_C1_2 PF03051.10 KFX86723.1 - 2.5e-53 181.1 0.2 2.7e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFX86723.1 - 0.0001 22.2 0.1 0.00011 22.1 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease DUF3107 PF11305.3 KFX86723.1 - 0.075 12.9 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Peptidase_M48 PF01435.13 KFX86725.1 - 1.8e-35 122.5 0.0 2.9e-34 118.6 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M48 Prothymosin PF03247.9 KFX86726.1 - 6.4 6.9 19.1 13 5.9 13.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ribosomal_L16 PF00252.13 KFX86728.1 - 1.6e-31 108.8 0.1 2.1e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e IncA PF04156.9 KFX86729.1 - 0.0011 18.6 12.8 0.0011 18.6 8.8 2.8 3 0 0 3 3 3 1 IncA protein Med23 PF11573.3 KFX86729.1 - 0.23 8.7 0.1 0.31 8.3 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 Phage_GPO PF05929.6 KFX86729.1 - 0.79 8.9 8.3 1.6 7.8 5.7 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3919 PF13057.1 KFX86729.1 - 2 7.8 7.5 0.24 10.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3919) FUSC PF04632.7 KFX86729.1 - 2.1 6.6 5.4 3.6 5.9 3.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 KFX86729.1 - 7.2 4.3 9.4 4.8 4.8 5.2 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cyt-b5 PF00173.23 KFX86730.1 - 1.6e-19 69.4 0.1 1.7e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 KFX86730.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Ceramidase PF05875.7 KFX86731.1 - 3.2e-72 242.8 4.8 3.7e-72 242.6 3.3 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_transf_64 PF09258.5 KFX86731.1 - 0.13 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain TACI-CRD2 PF09305.5 KFX86734.1 - 0.11 12.2 0.3 0.29 10.9 0.2 1.7 1 0 0 1 1 1 0 TACI, cysteine-rich domain Leader_Trp PF08255.6 KFX86734.1 - 1.8 8.3 6.5 15 5.5 0.6 3.4 2 0 0 2 2 2 0 Trp-operon Leader Peptide Abhydrolase_6 PF12697.2 KFX86737.1 - 1.8e-27 96.7 0.0 2.2e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX86737.1 - 3e-13 49.8 0.1 6e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX86737.1 - 1e-12 48.0 0.0 2.3e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KFX86737.1 - 4.9e-06 25.5 0.0 6.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 KFX86737.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KFX86737.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 KFX86737.1 - 0.0035 15.8 0.0 0.012 14.1 0.0 2.0 2 1 0 2 2 2 1 Ndr family FAD_binding_4 PF01565.18 KFX86738.1 - 3.6e-19 68.6 2.2 7.1e-19 67.6 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX86738.1 - 4.4e-11 42.4 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DSPc PF00782.15 KFX86739.1 - 8.9e-20 70.6 0.0 2e-19 69.5 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX86739.1 - 0.0046 16.3 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_3 PF07859.8 KFX86741.1 - 7.8e-17 61.5 0.1 6.7e-16 58.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX86741.1 - 7.4e-12 44.9 0.0 2.9e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 KFX86741.1 - 2.9e-10 39.1 0.2 0.00067 18.2 0.0 2.8 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 KFX86741.1 - 4.3e-09 36.2 0.0 6.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFX86741.1 - 5.2e-08 32.1 0.0 8.4e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFX86741.1 - 7.7e-08 31.4 0.0 1.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 KFX86741.1 - 8.2e-08 32.3 0.1 1e-07 32.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX86741.1 - 3.1e-07 29.5 0.3 5.3e-06 25.4 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.15 KFX86741.1 - 1.5e-05 24.5 0.0 3.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 KFX86741.1 - 6.6e-05 22.2 0.0 0.07 12.4 0.0 2.3 2 1 0 2 2 2 2 Dienelactone hydrolase family Lipase_3 PF01764.20 KFX86741.1 - 0.027 14.0 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 KFX86741.1 - 0.22 10.1 0.3 0.58 8.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KFX86742.1 - 5.6e-37 127.3 0.0 8.6e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX86742.1 - 3.7e-05 22.6 0.0 8.9e-05 21.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 KFX86742.1 - 0.00092 18.5 0.0 0.0019 17.5 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family GAF PF01590.21 KFX86742.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain Peptidase_S9 PF00326.16 KFX86742.1 - 0.038 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KFX86742.1 - 0.041 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.3 KFX86742.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 KFX86743.1 - 5.6e-43 146.9 0.0 6.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX86743.1 - 4e-10 39.0 0.3 1.1e-09 37.5 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFX86743.1 - 2.3e-05 24.1 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX86743.1 - 0.0032 16.7 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 KFX86743.1 - 0.0046 17.2 0.1 0.011 15.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFX86743.1 - 0.038 13.8 0.4 0.062 13.1 0.3 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KFX86743.1 - 0.049 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.3 KFX86743.1 - 0.093 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 KFX86743.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Aldolase_II PF00596.16 KFX86744.1 - 6.2e-10 38.9 0.1 8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain adh_short_C2 PF13561.1 KFX86746.1 - 1.2e-23 84.1 0.1 1.7e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX86746.1 - 5e-21 75.3 1.4 8e-21 74.6 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX86746.1 - 4e-07 29.8 0.1 7.9e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX86746.1 - 1.7e-06 27.6 0.6 0.0045 16.4 0.1 2.6 2 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFX86746.1 - 0.077 12.7 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 KFX86748.1 - 1.9e-16 59.7 4.3 3.1e-16 59.0 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX86748.1 - 1.9e-06 27.6 10.6 4.2e-06 26.5 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_A PF01968.13 KFX86749.1 - 2.2e-35 122.1 0.3 2.8e-35 121.8 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase MutL PF13941.1 KFX86749.1 - 0.11 10.7 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 MutL protein FAD_binding_3 PF01494.14 KFX86750.1 - 3.5e-20 72.3 0.0 1.4e-19 70.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX86750.1 - 4.4e-06 25.8 0.3 0.0049 15.8 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX86750.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX86750.1 - 0.026 13.4 0.2 0.16 10.8 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX86750.1 - 0.068 12.0 0.3 0.15 10.9 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KFX86750.1 - 0.097 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX86750.1 - 0.17 10.5 0.1 12 4.3 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase ADH_N PF08240.7 KFX86751.1 - 6e-29 99.9 0.5 6e-29 99.9 0.3 2.0 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX86751.1 - 3.7e-26 91.2 0.2 3.7e-26 91.2 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX86751.1 - 0.00079 18.6 0.1 0.0014 17.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MMR_HSR1 PF01926.18 KFX86752.1 - 2e-05 24.5 0.0 0.0001 22.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFX86752.1 - 3.9e-05 23.5 0.1 0.0012 18.6 0.0 2.7 2 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 KFX86752.1 - 0.00023 20.3 0.0 0.00047 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX86752.1 - 0.00085 19.3 2.4 0.078 12.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain IIGP PF05049.8 KFX86752.1 - 0.0021 16.9 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 KFX86752.1 - 0.0029 18.0 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 KFX86752.1 - 0.0038 16.2 0.0 0.0073 15.3 0.0 1.5 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 KFX86752.1 - 0.011 16.0 0.0 0.037 14.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KFX86752.1 - 0.024 13.6 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.1 KFX86752.1 - 0.031 14.4 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 KFX86752.1 - 0.035 13.1 0.1 0.083 11.9 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_29 PF13555.1 KFX86752.1 - 0.089 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain S1 PF00575.18 KFX86754.1 - 3.8e-82 270.3 41.2 3e-14 52.8 0.9 13.2 13 0 0 13 13 13 11 S1 RNA binding domain Suf PF05843.9 KFX86754.1 - 5.4e-06 26.3 3.5 0.0025 17.6 0.0 3.5 2 1 2 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KFX86754.1 - 4.4e-05 23.7 0.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX86754.1 - 0.00031 21.1 0.0 12 6.9 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 KFX86754.1 - 0.00037 19.4 1.2 0.0098 14.8 1.1 2.3 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 KFX86754.1 - 0.0014 19.2 0.0 14 6.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat S1_2 PF13509.1 KFX86754.1 - 0.012 15.4 0.1 12 5.8 0.0 4.2 3 0 0 3 3 3 0 S1 domain TPR_11 PF13414.1 KFX86754.1 - 0.021 14.4 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 TPR repeat EXOSC1 PF10447.4 KFX86754.1 - 6.5 6.7 11.2 8.9 6.3 0.1 5.8 8 1 0 8 8 8 0 Exosome component EXOSC1/CSL4 DOT1 PF08123.8 KFX86755.1 - 4.1e-72 241.8 0.1 6.1e-72 241.2 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KFX86755.1 - 0.054 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATG16 PF08614.6 KFX86756.1 - 5.1e-43 147.1 16.1 6e-43 146.9 11.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Scaffolding_pro PF11418.3 KFX86756.1 - 0.41 10.9 5.7 1.7 9.0 0.7 2.7 2 1 1 3 3 3 0 Phi29 scaffolding protein bZIP_1 PF00170.16 KFX86756.1 - 0.93 9.4 12.5 0.42 10.6 0.1 3.3 2 1 2 4 4 4 0 bZIP transcription factor V_ATPase_I PF01496.14 KFX86756.1 - 1.2 6.9 5.3 1.7 6.4 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 KFX86756.1 - 7.5 6.5 7.7 26 4.7 3.5 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Ras PF00071.17 KFX86757.1 - 1.5e-56 190.2 0.1 1.7e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX86757.1 - 5.6e-19 68.7 0.0 8.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX86757.1 - 8.7e-13 47.8 0.0 1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFX86757.1 - 2.5e-07 30.6 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFX86757.1 - 4.1e-07 29.3 0.0 5.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX86757.1 - 5.5e-07 29.1 0.0 2.2e-05 23.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFX86757.1 - 0.00081 19.5 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX86757.1 - 0.0011 18.1 0.1 0.0023 17.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 KFX86757.1 - 0.003 17.3 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KFX86757.1 - 0.0047 16.5 0.2 0.0092 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFX86757.1 - 0.0048 16.3 0.1 0.096 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KFX86757.1 - 0.005 16.4 0.3 0.18 11.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KFX86757.1 - 0.0064 16.2 0.2 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 KFX86757.1 - 0.0083 15.6 0.2 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 KFX86757.1 - 0.0086 15.3 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 KFX86757.1 - 0.0091 15.4 0.0 0.04 13.3 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KFX86757.1 - 0.0099 14.9 0.1 0.031 13.2 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_16 PF13191.1 KFX86757.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KFX86757.1 - 0.024 14.3 0.1 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KFX86757.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 KFX86757.1 - 0.071 12.3 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 KFX86757.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF914 PF06027.7 KFX86758.1 - 2.3e-08 33.2 10.2 2.3e-08 33.2 7.1 2.1 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFX86758.1 - 3.2e-07 30.4 8.7 3.2e-07 30.4 6.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFX86758.1 - 1.2e-05 25.5 7.5 1.2e-05 25.5 5.2 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KFX86758.1 - 2e-05 24.2 29.2 0.00029 20.5 4.7 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KFX86758.1 - 2.6e-05 23.2 12.1 8.4e-05 21.6 7.6 1.9 2 0 0 2 2 2 1 UAA transporter family Spb1_C PF07780.7 KFX86759.1 - 2.1e-76 256.2 10.0 2.1e-76 256.2 6.9 3.5 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KFX86759.1 - 2.5e-57 192.8 6.2 2.5e-57 192.8 4.3 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KFX86759.1 - 5.4e-54 182.9 0.1 1.1e-53 181.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFX86759.1 - 0.096 13.2 1.9 2.7 8.6 0.0 3.6 3 1 0 3 3 3 0 Methyltransferase domain Sugar_tr PF00083.19 KFX86762.1 - 2.1e-66 224.3 24.3 2.4e-66 224.1 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX86762.1 - 2e-06 26.7 39.9 6.3e-06 25.1 25.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fmp27 PF10344.4 KFX86763.1 - 6.7e-214 712.3 0.0 1.2e-213 711.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KFX86763.1 - 1.5e-169 564.7 5.1 1.5e-169 564.7 3.5 2.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KFX86763.1 - 1e-145 485.8 0.0 2.2e-145 484.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KFX86763.1 - 2.7e-54 183.1 0.2 6e-54 182.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KFX86763.1 - 1.9e-52 177.3 0.0 4.3e-52 176.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KFX86763.1 - 2.1e-32 111.6 0.0 7.9e-32 109.7 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain ELO PF01151.13 KFX86764.1 - 2.1e-63 213.9 20.7 2.5e-63 213.7 14.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1947 PF09183.5 KFX86764.1 - 0.18 11.5 2.4 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Ribosomal_L4 PF00573.17 KFX86765.1 - 3.3e-39 134.2 0.4 4.7e-39 133.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KFX86765.1 - 2.1e-27 94.7 1.5 3.1e-27 94.2 0.2 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain HDA2-3 PF11496.3 KFX86766.1 - 9e-15 54.2 0.0 2.8e-13 49.3 0.0 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AT_hook PF02178.14 KFX86766.1 - 0.23 11.2 23.9 0.028 14.0 2.0 3.7 3 0 0 3 3 3 0 AT hook motif CENP-F_leu_zip PF10473.4 KFX86766.1 - 1.7 8.4 38.2 0.014 15.2 4.7 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COX5A PF02284.11 KFX86767.1 - 1.1e-40 137.9 0.6 1.6e-40 137.4 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 KFX86767.1 - 0.063 11.6 0.2 0.38 9.0 0.0 1.9 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ER_lumen_recept PF00810.13 KFX86769.1 - 1.2e-53 181.5 11.0 2e-53 180.8 7.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF485 PF04341.7 KFX86769.1 - 0.011 15.3 0.1 0.011 15.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF485 PQ-loop PF04193.9 KFX86769.1 - 1.3 8.6 13.7 1.6 8.3 0.2 4.0 4 0 0 4 4 4 0 PQ loop repeat LSM14 PF12701.2 KFX86770.1 - 2.1e-34 117.2 0.0 4e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KFX86770.1 - 2e-15 57.1 5.3 6.8e-15 55.4 3.7 2.0 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 KFX86770.1 - 2e-06 27.6 0.0 4.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Spc7 PF08317.6 KFX86772.1 - 0.0014 17.3 1.5 0.0014 17.3 1.1 5.1 4 2 1 5 5 5 2 Spc7 kinetochore protein DUF1664 PF07889.7 KFX86772.1 - 0.0024 17.6 24.3 0.2 11.4 0.9 6.1 6 1 1 7 7 7 3 Protein of unknown function (DUF1664) HALZ PF02183.13 KFX86772.1 - 0.1 12.3 8.6 3.8 7.2 0.3 5.1 6 0 0 6 6 6 0 Homeobox associated leucine zipper AAA_13 PF13166.1 KFX86772.1 - 0.17 10.3 36.2 0.023 13.1 1.4 4.3 3 2 1 4 4 4 0 AAA domain Trns_repr_metal PF02583.12 KFX86772.1 - 7.2 6.8 13.7 4.1 7.6 0.1 4.6 5 0 0 5 5 5 0 Metal-sensitive transcriptional repressor TIP49 PF06068.8 KFX86773.1 - 3.6e-174 579.1 4.5 4.2e-174 578.9 3.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KFX86773.1 - 9e-09 34.7 1.3 0.00011 21.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KFX86773.1 - 1.6e-08 34.7 0.2 9.5e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KFX86773.1 - 2.5e-06 26.5 0.5 5e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KFX86773.1 - 5.8e-05 23.2 0.1 0.059 13.5 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX86773.1 - 8.3e-05 22.6 0.0 0.00054 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 KFX86773.1 - 0.00011 21.3 0.9 0.0037 16.4 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFX86773.1 - 0.00045 20.1 0.0 0.85 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KFX86773.1 - 0.0027 17.4 0.4 0.83 9.3 0.0 3.2 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFX86773.1 - 0.017 14.5 0.1 0.038 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFX86773.1 - 0.019 14.4 1.0 1 8.8 0.0 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 KFX86773.1 - 0.036 13.5 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KFX86773.1 - 0.04 13.6 0.3 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 KFX86773.1 - 0.11 12.0 0.4 0.2 11.2 0.3 1.5 1 1 0 1 1 1 0 AAA domain Chromo PF00385.19 KFX86774.1 - 4e-09 36.0 0.8 8e-09 35.0 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mago-bind PF09282.5 KFX86774.1 - 1.5e-05 24.4 0.3 4.8e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 Mago binding Ras PF00071.17 KFX86775.1 - 3.1e-63 211.9 0.2 3.6e-63 211.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX86775.1 - 6.4e-22 78.2 0.1 8.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX86775.1 - 8e-13 48.0 0.1 9.8e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFX86775.1 - 3.6e-08 33.3 0.1 5.4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX86775.1 - 9.2e-05 21.9 0.1 0.00031 20.2 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFX86775.1 - 0.00011 21.3 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KFX86775.1 - 0.00012 22.2 0.1 0.0003 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFX86775.1 - 0.0013 18.6 0.1 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX86775.1 - 0.0018 17.4 0.1 0.0037 16.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KFX86775.1 - 0.0044 16.1 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain SpoIIID PF12116.3 KFX86775.1 - 0.0074 16.2 0.1 0.087 12.7 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 KFX86775.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KFX86775.1 - 0.02 14.8 0.2 0.041 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFX86775.1 - 0.023 14.9 0.1 0.031 14.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 KFX86775.1 - 0.026 14.1 0.1 0.058 12.9 0.0 1.5 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 KFX86775.1 - 0.073 12.3 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KFX86775.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 KFX86775.1 - 0.13 10.9 0.1 1.2 7.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 KFX86775.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) F-box-like PF12937.2 KFX86776.1 - 0.00015 21.4 0.1 0.00015 21.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like WLM PF08325.5 KFX86777.1 - 9.5e-44 149.4 0.0 1.5e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KFX86777.1 - 0.0017 18.1 1.1 0.0041 16.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KFX86777.1 - 0.0098 15.5 0.4 0.016 14.9 0.0 1.5 2 0 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 KFX86777.1 - 0.015 15.3 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily ACBP PF00887.14 KFX86778.1 - 6.2e-31 105.9 0.0 2.1e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Atg14 PF10186.4 KFX86778.1 - 0.002 17.1 0.3 0.33 9.8 0.0 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 PRT_C PF08372.5 KFX86778.1 - 0.023 14.1 0.1 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal GFA PF04828.9 KFX86779.1 - 8.4e-20 70.5 0.0 1.1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFX86779.1 - 0.035 13.3 0.1 0.035 13.3 0.0 2.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-FCS PF06467.9 KFX86782.1 - 0.066 12.8 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AMP-binding PF00501.23 KFX86785.1 - 5.6e-56 189.7 0.5 2.1e-32 112.0 0.0 4.5 2 2 0 2 2 2 2 AMP-binding enzyme DUF2183 PF09949.4 KFX86785.1 - 1.2e-31 108.6 0.0 4.3e-31 106.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DMAP_binding PF06464.6 KFX86785.1 - 3.1e-12 47.0 2.0 5.4e-12 46.2 0.1 2.4 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 KFX86785.1 - 0.00075 19.2 0.4 0.0017 18.0 0.3 1.6 1 0 0 1 1 1 1 Gas vesicle protein G CarboxypepD_reg PF13620.1 KFX86785.1 - 0.065 13.3 1.3 0.76 9.8 0.1 2.9 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain DEAD PF00270.24 KFX86786.1 - 1.2e-43 148.5 0.0 2.7e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX86786.1 - 8.2e-25 86.4 0.0 1.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KFX86786.1 - 0.0081 14.6 0.0 0.0081 14.6 0.0 2.8 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) Acetyltransf_10 PF13673.1 KFX86787.1 - 0.001 19.1 0.0 0.0029 17.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX86787.1 - 0.0026 17.7 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KFX86787.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 KFX86788.1 - 3.1e-68 228.4 0.4 3.4e-68 228.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFX86788.1 - 6.6e-14 51.6 0.0 7.6e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFX86788.1 - 1.3e-12 47.1 1.1 3.5e-07 29.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFX86788.1 - 4.1e-10 40.1 0.0 5.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFX86788.1 - 5.5e-10 38.7 0.0 6.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX86788.1 - 1.3e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX86788.1 - 3.1e-07 29.7 0.0 3.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFX86788.1 - 5.2e-06 26.0 0.0 0.00054 19.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFX86788.1 - 0.033 13.4 0.2 0.096 11.9 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KFX86788.1 - 0.039 13.4 0.1 0.097 12.1 0.0 1.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KFX86788.1 - 0.046 14.5 0.1 0.059 14.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX86788.1 - 0.055 13.1 0.1 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 KFX86788.1 - 0.077 12.8 0.0 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.13 KFX86788.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 KFX86789.1 - 6.7e-94 315.5 42.0 2.9e-59 201.4 17.5 4.8 3 2 2 6 6 6 2 Domain of unknown function (DUF4045) PDEase_II PF02112.10 KFX86790.1 - 1.2e-55 188.8 0.0 6.6e-47 160.0 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KFX86790.1 - 0.001 18.6 0.3 0.0043 16.6 0.1 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFX86790.1 - 0.011 15.4 3.5 0.065 12.8 1.5 2.6 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily PSI_PSAK PF01241.13 KFX86790.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK zf-CCHC PF00098.18 KFX86791.1 - 1.4e-11 43.7 9.7 1.9e-05 24.3 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KFX86791.1 - 7.1e-08 31.9 0.2 1.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KFX86791.1 - 1.1e-06 28.2 5.5 0.00077 19.1 2.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KFX86791.1 - 0.00017 21.1 0.2 0.00041 19.9 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 KFX86791.1 - 0.0011 18.6 6.8 0.39 10.4 0.6 3.0 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 KFX86791.1 - 0.0011 18.5 6.0 0.3 10.7 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle FliT PF05400.8 KFX86791.1 - 0.61 10.5 3.2 31 5.0 0.4 3.2 3 0 0 3 3 3 0 Flagellar protein FliT GST_N_3 PF13417.1 KFX86792.1 - 3.4e-12 46.3 0.0 6.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX86792.1 - 3.2e-11 43.0 0.0 6.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFX86792.1 - 5.1e-11 42.4 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX86792.1 - 5.3e-11 42.5 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX86792.1 - 2.4e-09 36.9 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX86792.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ndufs5 PF10200.4 KFX86794.1 - 3.6e-05 23.6 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KFX86794.1 - 0.011 15.8 0.2 0.019 15.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX17 PF05051.8 KFX86794.1 - 0.07 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) BTB PF00651.26 KFX86795.1 - 2.6e-13 49.9 0.1 1.2e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_L30 PF00327.15 KFX86795.1 - 0.26 10.9 0.8 7.3 6.2 0.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L30p/L7e BTB PF00651.26 KFX86796.1 - 8.7e-08 32.1 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RILP PF11461.3 KFX86797.1 - 5.9e-05 23.1 0.0 14 5.9 0.0 5.3 1 1 4 5 5 5 3 Rab interacting lysosomal protein Ribosomal_S16 PF00886.14 KFX86797.1 - 0.0044 16.6 4.5 1 9.1 0.0 5.2 4 2 1 5 5 5 1 Ribosomal protein S16 Piwi PF02171.12 KFX86798.1 - 9.9e-72 241.4 0.0 1.7e-71 240.6 0.0 1.4 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KFX86798.1 - 2.6e-12 45.8 0.1 6.2e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KFX86798.1 - 1.1e-11 44.1 0.0 3.1e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 PAZ domain Pollen_allerg_2 PF01620.11 KFX86800.1 - 0.17 12.2 0.4 0.25 11.6 0.3 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) ADH_N PF08240.7 KFX86801.1 - 6.7e-09 35.4 2.1 1.4e-07 31.2 0.1 3.2 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX86801.1 - 1.6e-08 34.1 0.1 3.1e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2448 PF10476.4 KFX86801.1 - 0.1 12.0 0.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) NAD_Gly3P_dh_N PF01210.18 KFX86802.1 - 1e-43 148.8 0.1 2e-43 147.8 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KFX86802.1 - 1.2e-43 148.4 0.0 1.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KFX86802.1 - 0.044 14.2 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KFX86802.1 - 0.055 13.7 0.0 2 8.7 0.0 2.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 KFX86803.1 - 1.3e-12 47.7 0.0 2.1e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86803.1 - 4.8e-08 32.7 0.0 4e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX86803.1 - 9.2e-05 22.8 0.0 0.00022 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX86803.1 - 0.00021 21.6 0.0 0.00058 20.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86803.1 - 0.0029 18.1 0.1 0.024 15.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KFX86803.1 - 0.0061 15.8 0.0 0.026 13.8 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 KFX86803.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DAHP_synth_2 PF01474.11 KFX86805.1 - 1.7e-126 422.1 0.0 7.3e-73 245.4 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family AMP-binding PF00501.23 KFX86806.1 - 8.3e-64 215.5 0.0 9.8e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX86806.1 - 2.3e-07 31.6 0.0 1.1e-06 29.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF946 PF06101.6 KFX86806.1 - 0.12 10.3 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) DIOX_N PF14226.1 KFX86807.1 - 1.1e-21 77.4 0.1 1.9e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX86807.1 - 1.9e-14 53.7 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COX7a PF02238.10 KFX86807.1 - 0.071 12.8 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa ABC2_membrane PF01061.19 KFX86808.1 - 2.8e-74 248.8 53.2 2.3e-41 141.2 11.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KFX86808.1 - 6.2e-29 101.0 0.0 1.4e-13 51.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFX86808.1 - 1.8e-18 66.0 0.2 5.3e-17 61.3 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter AAA_29 PF13555.1 KFX86808.1 - 3.5e-06 26.4 2.3 0.024 14.1 0.1 4.3 3 1 1 4 4 4 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KFX86808.1 - 1.2e-05 24.7 0.5 0.013 14.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX86808.1 - 5.4e-05 23.3 0.2 5.4e-05 23.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KFX86808.1 - 0.00015 21.6 0.2 0.0098 15.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX86808.1 - 0.00042 19.6 0.1 0.12 11.5 0.0 3.5 4 1 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KFX86808.1 - 0.00081 19.3 0.2 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFX86808.1 - 0.0012 18.1 0.1 0.0042 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX86808.1 - 0.0018 18.3 1.0 0.13 12.3 0.1 3.4 3 2 1 4 4 3 1 AAA domain AAA_17 PF13207.1 KFX86808.1 - 0.012 16.3 0.0 0.094 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFX86808.1 - 0.022 15.0 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFX86808.1 - 0.027 14.9 0.0 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 KFX86808.1 - 0.03 13.9 0.9 0.14 11.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFX86808.1 - 0.034 13.8 0.1 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 KFX86808.1 - 0.036 14.0 3.1 0.48 10.3 0.4 2.9 2 1 1 3 3 3 0 AAA ATPase domain MMR_HSR1 PF01926.18 KFX86808.1 - 0.038 13.9 0.3 0.79 9.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFX86808.1 - 0.047 13.1 0.2 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KFX86808.1 - 0.067 12.2 0.2 1.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 KFX86808.1 - 0.076 12.0 0.0 0.64 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 KFX86808.1 - 0.093 12.4 0.1 18 4.9 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.1 KFX86808.1 - 0.11 12.8 0.2 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFX86808.1 - 0.18 10.6 0.8 2 7.2 0.1 2.5 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 KFX86808.1 - 0.6 9.5 1.7 1.2 8.5 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zn_clus PF00172.13 KFX86809.1 - 0.00081 19.2 10.4 0.00081 19.2 7.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFX86809.1 - 0.0048 17.1 2.8 0.0048 17.1 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX86809.1 - 0.023 15.0 1.0 0.023 15.0 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger EcKinase PF02958.15 KFX86810.1 - 9.3e-05 21.7 0.1 0.00014 21.1 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFX86810.1 - 0.00013 21.6 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFX86810.1 - 0.00082 19.1 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CorA PF01544.13 KFX86811.1 - 8.1e-31 107.1 11.7 3.9e-20 72.0 2.4 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF503 PF04456.7 KFX86811.1 - 0.039 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF503) DUF1516 PF07457.6 KFX86811.1 - 0.15 12.1 0.5 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) Plasmodium_Vir PF05795.6 KFX86811.1 - 0.19 10.9 0.0 0.37 9.9 0.0 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SQS_PSY PF00494.14 KFX86812.1 - 1.4e-47 162.1 0.0 2.2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 KFX86813.1 - 5e-72 242.2 0.0 6.7e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KFX86813.1 - 2.9e-26 91.4 0.0 7.1e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KFX86813.1 - 1.3e-11 44.1 0.0 2.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KFX86813.1 - 7.8e-07 29.0 8.1 1.5e-06 28.1 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KFX86813.1 - 9.9e-06 25.4 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KFX86813.1 - 5.7e-05 22.6 8.0 0.00011 21.8 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX86813.1 - 0.00036 20.1 5.6 0.00066 19.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX86813.1 - 0.0017 18.1 7.5 0.0033 17.2 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain ACT_3 PF10000.4 KFX86813.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain AAA_22 PF13401.1 KFX86813.1 - 0.011 15.8 0.0 0.17 12.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain zf-RING_5 PF14634.1 KFX86813.1 - 0.041 13.6 7.1 0.15 11.8 5.1 1.9 1 1 1 2 2 2 0 zinc-RING finger domain UBA_4 PF14555.1 KFX86813.1 - 0.06 12.8 0.1 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Carb_anhydrase PF00194.16 KFX86814.1 - 5.1e-18 64.9 0.2 5.3e-10 38.6 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Sugar_tr PF00083.19 KFX86816.1 - 5.8e-64 216.3 30.0 7e-64 216.0 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX86816.1 - 1.7e-19 69.7 45.2 8.4e-13 47.7 17.4 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX86816.1 - 0.00022 19.7 2.4 0.00022 19.7 1.7 3.2 3 1 0 3 3 3 1 MFS/sugar transport protein S10_plectin PF03501.10 KFX86818.1 - 4.9e-26 90.4 0.1 6.8e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 KFX86819.1 - 9.7e-68 226.9 0.5 1.7e-67 226.1 0.4 1.4 1 0 0 1 1 1 1 Telomere stability and silencing DUF605 PF04652.11 KFX86819.1 - 0.76 9.1 15.5 1.1 8.5 10.8 1.1 1 0 0 1 1 1 0 Vta1 like COX6B PF02297.12 KFX86820.1 - 2.9e-20 72.0 5.3 3.6e-20 71.7 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KFX86820.1 - 0.008 15.5 1.6 0.013 14.8 1.1 1.6 1 1 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 KFX86820.1 - 0.09 12.2 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UPF0203 PF05254.7 KFX86820.1 - 0.86 9.4 4.2 2.3 8.1 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) B12D PF06522.6 KFX86821.1 - 3.4e-05 23.4 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 KFX86822.1 - 4.5e-16 58.2 0.0 6.8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX86822.1 - 5.4e-12 45.5 0.0 7.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86822.1 - 4.9e-08 32.7 0.0 7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2167 PF09935.4 KFX86822.1 - 0.062 12.1 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) HECT PF00632.20 KFX86823.1 - 5.3e-72 242.6 0.0 7.7e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WD40 PF00400.27 KFX86823.1 - 1.8e-16 59.2 0.1 0.00013 21.7 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.6 KFX86823.1 - 1.3e-10 41.2 0.0 6.3e-10 38.9 0.0 2.2 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KFX86823.1 - 0.00052 19.8 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 KFX86823.1 - 0.03 13.8 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain C1_1 PF00130.17 KFX86823.1 - 0.043 13.5 0.4 0.094 12.4 0.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Dak1_2 PF13684.1 KFX86823.1 - 0.56 9.0 0.2 0.99 8.2 0.2 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family L51_S25_CI-B8 PF05047.11 KFX86824.1 - 1.5e-19 69.4 0.2 2.8e-19 68.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF832 PF05734.6 KFX86824.1 - 0.11 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) MMR_HSR1 PF01926.18 KFX86825.1 - 6.4e-05 22.8 0.0 0.00038 20.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ribosomal_L16 PF00252.13 KFX86826.1 - 6.3e-28 97.1 0.1 8.1e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 KFX86827.1 - 3.7e-58 195.6 0.2 8.4e-57 191.2 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KFX86827.1 - 1.7e-13 50.5 0.0 4.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KFX86827.1 - 3.3e-08 33.7 0.1 1.9e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KFX86827.1 - 1.7e-06 27.0 0.0 2.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KFX86827.1 - 7.2e-06 26.8 0.2 6.6e-05 23.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX86827.1 - 1.2e-05 25.4 0.0 4.4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX86827.1 - 0.00014 22.1 1.9 0.0029 17.9 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX86827.1 - 0.004 17.1 0.9 0.034 14.1 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KFX86827.1 - 0.0078 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFX86827.1 - 0.008 16.1 0.1 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 KFX86827.1 - 0.013 14.9 0.0 0.036 13.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.1 KFX86827.1 - 0.019 14.7 0.0 0.059 13.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PTCB-BRCT PF12738.2 KFX86827.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Muted PF14942.1 KFX86827.1 - 0.66 9.8 7.4 0.25 11.1 2.5 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Arch_ATPase PF01637.13 KFX86827.1 - 2.8 7.5 7.5 7.9 6.0 1.1 3.3 2 1 0 2 2 2 0 Archaeal ATPase ECH PF00378.15 KFX86828.1 - 9.5e-26 90.3 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 KFX86828.1 - 1.4e-09 37.1 0.0 2.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ACOX PF01756.14 KFX86829.1 - 5.1e-38 130.3 0.0 1.1e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.19 KFX86829.1 - 0.023 14.7 0.4 0.46 10.5 0.3 2.2 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 KFX86830.1 - 7.9e-29 100.4 37.8 7.9e-29 100.4 26.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KFX86830.1 - 5.1e-05 21.5 5.2 0.0017 16.5 3.6 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 KFX86831.1 - 9.9e-59 198.7 0.1 1.2e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX86831.1 - 5.4e-10 40.0 0.0 3.1e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SOG2 PF10428.4 KFX86832.1 - 2.1e-88 296.9 1.8 2.1e-88 296.9 1.3 2.5 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 KFX86832.1 - 3.2e-20 71.2 4.2 9e-09 34.7 0.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX86832.1 - 1.7e-17 62.9 3.2 8.3e-11 41.4 0.7 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFX86832.1 - 1.2e-10 39.8 4.7 0.14 12.2 0.1 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFX86832.1 - 1.1e-08 33.8 0.9 12 6.6 0.0 6.0 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KFX86832.1 - 0.0048 16.8 6.8 17 5.8 0.1 5.1 5 0 0 5 5 5 2 Leucine Rich repeat HemN_C PF06969.11 KFX86832.1 - 0.084 12.9 0.2 1.9 8.6 0.0 2.9 2 1 1 3 3 3 0 HemN C-terminal domain MRP-S25 PF13741.1 KFX86833.1 - 2.7e-75 252.7 8.0 1.1e-73 247.5 5.6 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_2 PF13041.1 KFX86834.1 - 5.4e-17 61.5 2.3 2.2e-05 24.3 0.0 5.5 3 2 2 5 5 5 4 PPR repeat family PPR_3 PF13812.1 KFX86834.1 - 8.9e-11 41.1 5.2 0.0019 18.3 0.1 5.5 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 KFX86834.1 - 1.2e-10 40.5 5.6 6.3e-05 22.6 0.1 5.2 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 KFX86834.1 - 0.041 13.3 5.9 0.053 13.0 0.0 3.5 4 1 0 4 4 4 0 PPR repeat WD40 PF00400.27 KFX86835.1 - 9.4e-31 104.5 10.6 9.1e-10 38.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFX86835.1 - 9.9e-07 27.3 0.2 5.7e-06 24.8 0.1 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 KFX86835.1 - 4.9e-05 23.1 0.0 0.0091 15.7 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KFX86835.1 - 7.4e-05 21.9 0.3 0.063 12.3 0.0 3.4 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 KFX86835.1 - 0.0096 14.7 0.0 0.039 12.7 0.0 1.6 1 1 1 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 KFX86835.1 - 0.018 13.7 0.0 1.3 7.6 0.0 2.1 1 1 2 3 3 3 0 Nup133 N terminal like Ribosomal_L32p PF01783.18 KFX86836.1 - 1.2e-12 47.7 2.0 2.2e-12 46.9 1.4 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.7 KFX86836.1 - 0.039 13.7 0.5 0.065 13.0 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.1 KFX86836.1 - 0.44 9.8 3.2 0.87 8.8 2.2 1.5 1 1 0 1 1 1 0 zinc-ribbon domain Septin PF00735.13 KFX86837.1 - 1.3e-111 372.1 0.3 1.5e-111 371.9 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFX86837.1 - 6.4e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFX86837.1 - 4.2e-06 26.0 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KFX86837.1 - 3.9e-05 22.8 0.0 6.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFX86837.1 - 0.00053 19.8 0.5 1.3 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KFX86837.1 - 0.00078 18.9 0.2 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KFX86837.1 - 0.0027 18.0 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFX86837.1 - 0.003 17.0 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 KFX86837.1 - 0.011 16.0 0.2 0.02 15.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFX86837.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KFX86837.1 - 0.02 13.8 0.1 0.054 12.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 KFX86837.1 - 0.031 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 KFX86837.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KFX86837.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 KFX86837.1 - 0.035 13.2 0.1 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Herpes_UL49_5 PF05702.6 KFX86838.1 - 0.039 13.8 0.2 0.077 12.8 0.2 1.6 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein SEEEED PF14797.1 KFX86838.1 - 1.6 8.8 21.4 2.4 8.2 14.8 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Ydc2-catalyt PF09159.5 KFX86839.1 - 6.4e-72 242.3 0.0 8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 KFX86839.1 - 4.3e-08 33.1 0.0 0.0015 18.4 0.0 3.1 2 1 0 2 2 2 2 Poxvirus A22 protein SAP PF02037.22 KFX86839.1 - 2.4e-07 30.0 0.1 5.2e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain SRP72 PF08492.7 KFX86839.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 SRP72 RNA-binding domain Pyr_redox_2 PF07992.9 KFX86840.1 - 3.7e-38 131.4 2.1 7.5e-38 130.4 1.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFX86840.1 - 5e-35 119.8 0.2 2.4e-33 114.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFX86840.1 - 1.1e-16 60.9 1.1 1.1e-15 57.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 KFX86840.1 - 1.6e-10 40.9 0.0 4.9e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX86840.1 - 3e-09 37.2 0.0 7.9e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.1 KFX86840.1 - 1.5e-07 31.6 0.1 2.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.7 KFX86840.1 - 2e-07 31.3 0.0 6.9e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86840.1 - 5.1e-07 29.3 0.0 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86840.1 - 0.00023 21.7 0.3 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain K_oxygenase PF13434.1 KFX86840.1 - 0.0032 16.4 0.0 0.0085 15.0 0.0 1.7 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KFX86840.1 - 0.0063 15.6 0.4 0.0089 15.1 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX86840.1 - 0.028 13.2 4.4 0.27 10.0 1.1 2.9 3 0 0 3 3 3 0 FAD binding domain Methyltransf_26 PF13659.1 KFX86840.1 - 0.028 14.4 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KFX86840.1 - 0.078 12.1 0.3 1.7 7.8 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KFX86840.1 - 0.098 11.5 4.5 0.11 11.3 1.8 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KFX86840.1 - 0.14 11.0 1.3 0.38 9.5 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KFX86840.1 - 1.1 7.7 7.4 2.4 6.5 0.6 3.3 3 1 1 4 4 4 0 HI0933-like protein NAD_binding_8 PF13450.1 KFX86840.1 - 1.2 9.1 3.7 4 7.5 2.3 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Guanylate_kin PF00625.16 KFX86841.1 - 1.3e-46 158.3 0.9 1.3e-46 158.3 0.6 2.2 3 0 0 3 3 3 1 Guanylate kinase Helicase_C PF00271.26 KFX86841.1 - 1.4e-21 76.1 0.0 6.1e-17 61.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KFX86841.1 - 5.4e-17 61.7 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1895 PF08988.5 KFX86841.1 - 0.24 11.4 2.2 0.23 11.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) Glyco_hydro_15 PF00723.16 KFX86842.1 - 9.7e-10 37.5 0.1 5.6e-07 28.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_72 PF03198.9 KFX86842.1 - 0.068 12.1 0.1 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 Glucanosyltransferase T5orf172 PF10544.4 KFX86843.1 - 1.6e-17 63.7 0.4 1.6e-16 60.5 0.2 2.5 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 KFX86843.1 - 2.3e-13 50.3 0.1 7.3e-11 42.3 0.2 2.8 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 DUF390 PF04094.9 KFX86843.1 - 0.0046 15.0 33.7 0.0079 14.3 23.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF390) CRT10 PF08728.5 KFX86843.1 - 6.9 4.5 6.3 9.1 4.1 4.3 1.1 1 0 0 1 1 1 0 CRT10 Choline_transpo PF04515.7 KFX86845.1 - 0.0043 15.8 3.8 0.0043 15.8 2.6 1.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter DUF1068 PF06364.7 KFX86845.1 - 0.033 13.8 0.3 0.07 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) IF4E PF01652.13 KFX86847.1 - 7.8e-52 175.1 0.1 1e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 KFX86848.1 - 7e-34 117.3 0.0 1.9e-33 115.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain F-box-like PF12937.2 KFX86849.1 - 2.6e-06 27.0 1.1 2.6e-06 27.0 0.7 2.6 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.2 KFX86849.1 - 0.031 13.9 3.0 6.4 6.5 0.9 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-CW PF07496.10 KFX86849.1 - 0.067 12.9 1.5 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 CW-type Zinc Finger F-box PF00646.28 KFX86849.1 - 4.7 6.9 5.9 12 5.6 1.8 2.7 3 0 0 3 3 3 0 F-box domain Mannosyl_trans PF05007.8 KFX86850.1 - 3e-75 253.2 15.7 4.9e-75 252.5 10.9 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KFX86850.1 - 5.2e-08 32.1 21.7 1.5e-07 30.6 15.0 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KFX86850.1 - 1e-05 25.1 17.4 1e-05 25.1 12.0 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) HPD PF05044.7 KFX86850.1 - 0.12 12.0 0.3 0.2 11.3 0.2 1.2 1 0 0 1 1 1 0 Homeo-prospero domain Translin PF01997.11 KFX86851.1 - 3.8e-55 186.5 0.0 4.5e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Lge1 PF11488.3 KFX86851.1 - 0.02 15.0 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 BolA PF01722.13 KFX86852.1 - 8.3e-29 99.3 2.1 9.9e-29 99.1 1.4 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 KFX86852.1 - 0.067 13.6 0.1 0.083 13.3 0.1 1.3 1 1 0 1 1 1 0 Replication protein A C terminal bact-PGI_C PF10432.4 KFX86852.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region AMP-binding PF00501.23 KFX86853.1 - 1.8e-69 234.1 0.0 2.1e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX86853.1 - 2.2e-15 57.3 0.1 5.3e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 KFX86854.1 - 3.7e-59 198.9 0.1 4.4e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 KFX86855.1 - 1.5e-23 82.2 3.0 2.5e-23 81.4 2.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPP1 PF10341.4 KFX86855.1 - 1.3e-07 31.4 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD PIP5K PF01504.13 KFX86856.1 - 8.8e-60 201.9 0.0 1.7e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KFX86856.1 - 1e-25 90.3 0.0 1.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KFX86856.1 - 2.2e-12 46.6 9.8 5.7e-12 45.3 6.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger Metallophos PF00149.23 KFX86857.1 - 1.1e-39 135.9 0.1 1.4e-39 135.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SET PF00856.23 KFX86858.1 - 5.5e-19 69.0 0.9 5.4e-18 65.8 0.1 3.0 3 1 0 3 3 3 1 SET domain RPEL PF02755.10 KFX86859.1 - 1.2e-23 81.6 18.0 1e-09 37.3 2.0 3.9 4 0 0 4 4 4 3 RPEL repeat MCPVI PF02993.9 KFX86859.1 - 0.041 14.0 3.2 0.035 14.2 1.3 1.5 1 1 0 1 1 1 0 Minor capsid protein VI CP12 PF02672.10 KFX86859.1 - 0.069 13.6 0.4 18 5.8 0.1 2.5 2 0 0 2 2 2 0 CP12 domain IMS PF00817.15 KFX86860.1 - 7.1e-41 139.4 0.2 1.7e-40 138.2 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KFX86860.1 - 3.3e-10 39.9 0.0 7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFX86860.1 - 0.0014 18.5 0.0 0.0042 17.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif FKBP_C PF00254.23 KFX86861.1 - 2.2e-33 114.1 0.0 3.5e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I53 PF11714.3 KFX86861.1 - 0.085 12.8 0.6 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Pkinase PF00069.20 KFX86864.1 - 1.9e-63 214.0 0.0 3.5e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86864.1 - 4.2e-27 94.8 0.0 6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX86864.1 - 0.0082 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX86864.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KFX86864.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NTP_transferase PF00483.18 KFX86865.1 - 7.8e-48 162.9 0.0 1.5e-47 162.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KFX86865.1 - 6.5e-16 57.0 12.3 1e-09 37.4 1.3 4.2 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFX86865.1 - 4.4e-11 43.1 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KFX86865.1 - 1.1e-06 28.0 1.3 1.1e-06 28.0 0.9 3.0 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Transket_pyr PF02779.19 KFX86866.1 - 2.6e-63 212.7 0.0 4.5e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFX86866.1 - 2.6e-55 187.2 0.0 3.9e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component BSD PF03909.12 KFX86867.1 - 1.4e-23 82.4 5.3 1.1e-13 50.7 0.2 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KFX86867.1 - 1.7e-23 82.0 0.1 4.6e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DUF607 PF04678.8 KFX86869.1 - 5.2e-39 134.0 0.8 5.2e-39 134.0 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF607 AAA_27 PF13514.1 KFX86869.1 - 0.0047 14.6 1.9 0.0056 14.4 1.3 1.0 1 0 0 1 1 1 1 AAA domain DUF2530 PF10745.4 KFX86869.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Vfa1 PF08432.5 KFX86869.1 - 1.4 8.9 8.4 1.7 8.6 5.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 KFX86869.1 - 1.9 7.2 8.3 2 7.1 5.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YtxH PF12732.2 KFX86869.1 - 5.3 7.4 6.0 11 6.5 4.2 1.4 1 0 0 1 1 1 0 YtxH-like protein FLO_LFY PF01698.11 KFX86869.1 - 7.2 5.3 9.5 16 4.2 6.6 1.5 1 1 0 1 1 1 0 Floricaula / Leafy protein Apolipoprotein PF01442.13 KFX86871.1 - 0.0018 17.7 9.1 0.003 17.0 4.8 2.1 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Gp58 PF07902.6 KFX86871.1 - 0.0045 15.2 4.5 0.0079 14.4 3.1 1.3 1 1 0 1 1 1 1 gp58-like protein Borrelia_REV PF03978.8 KFX86871.1 - 0.067 12.9 3.3 0.15 11.8 2.0 1.8 1 1 1 2 2 2 0 Borrelia burgdorferi REV protein Mer2 PF09074.5 KFX86871.1 - 0.13 12.2 8.6 0.72 9.7 2.1 2.4 1 1 1 2 2 2 0 Mer2 V-ATPase_G PF03179.10 KFX86871.1 - 0.23 11.7 5.5 0.082 13.2 1.1 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Prominin PF05478.6 KFX86871.1 - 0.28 8.6 3.1 0.15 9.5 0.5 1.6 1 1 1 2 2 2 0 Prominin AAA_13 PF13166.1 KFX86871.1 - 0.31 9.4 9.2 0.14 10.5 3.4 1.7 1 1 1 2 2 2 0 AAA domain Baculo_PEP_C PF04513.7 KFX86871.1 - 0.69 9.7 4.2 0.52 10.1 0.6 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOBP PF15279.1 KFX86871.1 - 0.87 9.9 12.0 1.3 9.3 8.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1515 PF07439.6 KFX86871.1 - 0.91 9.3 4.3 1.1 9.0 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) PBP_dimer PF03717.10 KFX86871.1 - 1.5 8.8 7.7 5.6 6.9 2.8 2.7 2 1 0 2 2 2 0 Penicillin-binding Protein dimerisation domain LMP PF04778.7 KFX86871.1 - 2.6 7.7 8.2 1.5 8.5 0.2 3.1 1 1 2 3 3 3 0 LMP repeated region DUF4404 PF14357.1 KFX86871.1 - 3.7 8.0 8.7 4.3 7.8 1.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DEAD PF00270.24 KFX86872.1 - 6.5e-45 152.6 1.2 1.2e-44 151.7 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX86872.1 - 1.3e-27 95.4 0.2 6.1e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX86872.1 - 0.00085 19.1 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFX86872.1 - 0.0027 17.3 0.1 0.0084 15.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX86872.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 KFX86872.1 - 0.017 14.2 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 KFX86872.1 - 0.017 14.8 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain CobA_CobO_BtuR PF02572.10 KFX86872.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 KFX86872.1 - 0.092 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein Flavi_DEAD PF07652.9 KFX86872.1 - 0.094 12.4 0.1 0.47 10.1 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.16 KFX86872.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain NuA4 PF09340.5 KFX86873.1 - 8.5e-24 83.0 0.1 1.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 SIMPL PF04402.9 KFX86877.1 - 5.6e-30 104.7 4.0 6.5e-30 104.5 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF4424 PF14415.1 KFX86877.1 - 0.032 13.7 0.1 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Fungal_trans_2 PF11951.3 KFX86878.1 - 3.3e-19 68.7 0.0 5.3e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX86878.1 - 3.8e-05 23.5 10.7 6.4e-05 22.7 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.8 KFX86879.1 - 3.6e-15 55.1 0.0 4.7e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFX86879.1 - 7.7e-14 51.6 0.1 1.2e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX86879.1 - 3.9e-07 30.1 0.1 5.9e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFX86879.1 - 4.9e-06 25.6 0.0 1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFX86879.1 - 0.0081 14.9 0.5 0.12 11.1 0.3 2.1 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.15 KFX86879.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFX86879.1 - 0.041 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Beta-lactamase PF00144.19 KFX86880.1 - 6.9e-45 153.4 0.0 9.7e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KFX86880.1 - 4.1e-09 36.1 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ribonucleas_3_3 PF14622.1 KFX86881.1 - 4.3e-09 36.4 0.0 5.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFX86881.1 - 2.3e-08 34.4 0.0 5.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain RabGAP-TBC PF00566.13 KFX86882.1 - 3.7e-37 127.8 0.0 7.5e-36 123.6 0.0 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Sod_Fe_C PF02777.13 KFX86883.1 - 5.5e-38 129.0 0.7 5.5e-38 129.0 0.5 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFX86883.1 - 4e-29 100.7 2.3 6.5e-29 100.0 1.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KFX86883.1 - 0.077 12.0 1.3 2.3 7.3 0.0 3.3 3 1 1 4 4 4 0 Immunity protein 15 DUF4211 PF13926.1 KFX86885.1 - 1.7e-15 56.7 0.0 5.1e-15 55.1 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) CENP-B_dimeris PF09026.5 KFX86885.1 - 0.0029 17.8 1.2 0.0045 17.2 0.9 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KFX86885.1 - 0.03 14.6 0.5 0.051 13.8 0.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2201_N PF13203.1 KFX86885.1 - 0.052 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Nucleoplasmin PF03066.10 KFX86885.1 - 0.093 12.2 3.3 0.14 11.7 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin PP2C PF00481.16 KFX86886.1 - 7.6e-63 212.2 0.7 1e-50 172.5 0.3 3.1 3 0 0 3 3 3 2 Protein phosphatase 2C Hs1pro-1_C PF07014.7 KFX86886.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Snf7 PF03357.16 KFX86887.1 - 2.2e-36 124.8 19.9 3.4e-36 124.2 13.8 1.3 1 0 0 1 1 1 1 Snf7 WASH_WAHD PF11945.3 KFX86887.1 - 0.023 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex Ist1 PF03398.9 KFX86887.1 - 0.071 12.5 5.8 0.12 11.7 4.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Peptidase_S46 PF10459.4 KFX86887.1 - 0.18 10.1 5.4 0.22 9.8 3.8 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF592 PF04574.8 KFX86887.1 - 0.67 9.4 3.9 7 6.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF592) DSBA PF01323.15 KFX86887.1 - 4.9 6.6 6.2 7.2 6.1 4.3 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain YlqD PF11068.3 KFX86887.1 - 7.4 6.6 18.2 2.1 8.3 5.4 2.2 1 1 1 2 2 2 0 YlqD protein Aminotran_3 PF00202.16 KFX86888.1 - 3.6e-49 167.4 0.1 5.4e-49 166.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KFX86888.1 - 0.03 13.4 0.0 0.098 11.7 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase NifW PF03206.9 KFX86888.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW GxDLY PF14607.1 KFX86891.1 - 0.05 13.0 0.0 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 N-terminus of Esterase_SGNH_hydro-type Pkinase PF00069.20 KFX86893.1 - 4.1e-70 235.9 0.0 7.1e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86893.1 - 3.7e-35 121.2 0.0 6.4e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX86893.1 - 0.00035 19.6 0.0 0.00067 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX86893.1 - 0.0005 19.1 0.1 0.0019 17.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Ribosomal_L19 PF01245.15 KFX86895.1 - 4.2e-19 68.4 0.1 7.1e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.20 KFX86897.1 - 4.1e-60 203.5 0.2 4.8e-60 203.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 KFX86898.1 - 1.2e-96 323.1 0.9 1.2e-96 323.1 0.6 2.8 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KFX86898.1 - 1.8e-09 37.7 11.6 4.2e-05 23.7 0.8 5.4 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.17 KFX86898.1 - 1.5e-06 27.7 9.0 0.05 13.6 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.2 KFX86898.1 - 0.018 14.8 1.3 0.75 9.6 0.2 4.2 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 KFX86898.1 - 0.023 13.8 2.4 3.5 6.6 0.1 3.0 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.1 KFX86898.1 - 2 9.0 18.6 0.28 11.7 0.8 6.6 4 1 3 7 7 7 0 HEAT-like repeat PARG_cat PF05028.9 KFX86899.1 - 5.1e-36 124.5 0.0 1.2e-35 123.3 0.0 1.5 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) NAP PF00956.13 KFX86900.1 - 4.2e-48 163.5 0.4 5.5e-48 163.2 0.3 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Tau95 PF09734.4 KFX86901.1 - 2e-62 211.3 0.0 2.5e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit RNA_pol_3_Rpc31 PF11705.3 KFX86901.1 - 0.46 10.3 18.2 1.4 8.8 12.6 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 KFX86901.1 - 0.82 8.8 9.3 1.3 8.2 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein B56 PF01603.15 KFX86902.1 - 4.9e-172 572.1 6.1 6e-172 571.8 4.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Syntaxin-6_N PF09177.6 KFX86903.1 - 1.7e-24 86.0 1.4 1.7e-23 82.8 0.0 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KFX86903.1 - 3.3e-12 45.9 2.6 3.3e-12 45.9 1.8 3.2 3 0 0 3 3 3 1 SNARE domain DUF869 PF05911.6 KFX86903.1 - 0.0019 16.5 1.3 0.0023 16.2 0.9 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Herpes_UL6 PF01763.11 KFX86903.1 - 0.046 11.9 2.1 0.061 11.5 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Myosin_tail_1 PF01576.14 KFX86903.1 - 0.17 9.5 10.3 0.65 7.6 4.2 2.0 1 1 1 2 2 2 0 Myosin tail CENP-Q PF13094.1 KFX86903.1 - 0.2 11.6 9.7 0.77 9.7 6.7 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Rifin_STEVOR PF02009.11 KFX86903.1 - 0.21 11.1 0.7 0.44 10.1 0.4 1.6 1 1 0 1 1 1 0 Rifin/stevor family DUF1664 PF07889.7 KFX86903.1 - 0.33 10.7 3.7 0.96 9.2 0.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.6 KFX86903.1 - 0.63 8.4 7.1 1.6 7.1 4.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 KFX86903.1 - 0.67 9.5 5.4 2.1 7.9 3.7 1.8 1 1 0 1 1 1 0 Mnd1 family APG6 PF04111.7 KFX86903.1 - 1.7 7.6 7.7 0.64 9.0 0.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KFX86903.1 - 2.2 8.1 11.1 7.2 6.4 6.8 2.0 1 1 1 2 2 2 0 Tropomyosin like Methyltransf_32 PF13679.1 KFX86904.1 - 6.1e-18 64.8 3.1 5.5e-17 61.7 2.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Sdh_cyt PF01127.17 KFX86905.1 - 1.4e-24 86.2 4.2 1.8e-24 85.8 2.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 KFX86906.1 - 9.9e-32 108.9 0.1 8.3e-31 105.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 KFX86906.1 - 2.8e-21 75.2 0.1 6.1e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Adaptin_N PF01602.15 KFX86906.1 - 0.026 12.8 1.8 0.028 12.7 0.4 1.5 2 0 0 2 2 2 0 Adaptin N terminal region Histone PF00125.19 KFX86906.1 - 0.037 14.1 0.1 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Thymidylate_kin PF02223.12 KFX86907.1 - 2.2e-49 167.3 0.0 2.6e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KFX86907.1 - 2.4e-07 30.8 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX86907.1 - 0.00065 20.0 0.4 0.022 15.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain PRK PF00485.13 KFX86907.1 - 0.0011 18.5 0.0 0.0033 17.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 KFX86907.1 - 0.0043 16.2 1.5 0.0092 15.2 0.1 2.1 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFX86907.1 - 0.0054 17.5 0.3 0.0094 16.7 0.2 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KFX86907.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase ThiI PF02568.9 KFX86907.1 - 0.12 11.8 0.1 0.34 10.3 0.1 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) GTP_cyclohydroI PF01227.17 KFX86908.1 - 5.2e-73 244.1 0.1 6.7e-73 243.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KFX86908.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein HATPase_c PF02518.21 KFX86909.1 - 3.2e-18 65.4 0.1 1.8e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFX86909.1 - 0.00012 21.9 0.0 0.00049 20.0 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KFX86909.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Metalloenzyme PF01676.13 KFX86910.1 - 4.4e-73 245.7 0.2 5.1e-73 245.5 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KFX86910.1 - 1.5e-71 240.2 0.0 2.4e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KFX86910.1 - 5.5e-09 35.8 0.1 1.1e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX86910.1 - 2.8e-08 33.3 0.0 9.8e-08 31.5 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 KFX86910.1 - 0.053 12.2 0.0 0.088 11.4 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase AP_endonuc_2 PF01261.19 KFX86910.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Med9 PF07544.8 KFX86911.1 - 3e-19 68.5 0.0 5.1e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HHH_8 PF14716.1 KFX86911.1 - 0.0028 17.8 0.7 0.7 10.1 0.1 2.2 1 1 1 2 2 2 2 Helix-hairpin-helix domain Med21 PF11221.3 KFX86911.1 - 0.041 13.8 9.0 0.12 12.3 6.2 1.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Herpes_BLLF1 PF05109.8 KFX86911.1 - 1.9 6.3 11.4 2 6.2 7.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TBCC PF07986.7 KFX86912.1 - 1e-33 115.2 0.4 1.8e-33 114.4 0.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C K-box PF01486.12 KFX86912.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 K-box region Tim17 PF02466.14 KFX86913.1 - 2.7e-14 53.3 9.5 3.9e-14 52.7 6.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.24 KFX86914.1 - 1.2e-37 129.4 0.0 4.5e-37 127.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KFX86914.1 - 4.5e-32 109.2 2.4 1.2e-12 47.0 0.2 4.4 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KFX86914.1 - 9e-15 54.8 2.1 1.1e-06 28.2 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.22 KFX86916.1 - 3.5e-60 199.7 4.5 7.2e-21 73.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 KFX86916.1 - 1.2e-29 103.1 1.4 2.2e-29 102.1 0.9 1.4 1 0 0 1 1 1 1 Sec34-like family RCC1 PF00415.13 KFX86917.1 - 8e-26 90.0 10.1 0.00012 22.2 0.0 8.2 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFX86917.1 - 9.5e-10 37.8 19.7 4.4e-07 29.3 0.2 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Borrelia_P83 PF05262.6 KFX86918.1 - 0.18 10.0 22.5 0.22 9.7 15.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 KFX86918.1 - 0.4 10.0 38.1 0.56 9.5 26.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 KFX86918.1 - 0.87 9.4 9.1 1.2 9.0 6.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPP4R2 PF09184.6 KFX86918.1 - 1.1 8.7 18.0 23 4.4 12.2 2.0 2 0 0 2 2 2 0 PPP4R2 CRT10 PF08728.5 KFX86918.1 - 1.1 7.1 12.2 1.3 6.8 8.4 1.0 1 0 0 1 1 1 0 CRT10 MIP-T3 PF10243.4 KFX86918.1 - 1.5 7.1 32.7 2 6.7 22.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Toxin_25 PF08095.6 KFX86918.1 - 3 7.6 5.4 2.1 8.1 0.4 2.6 2 0 0 2 2 2 0 Hefutoxin family DUF1510 PF07423.6 KFX86918.1 - 3.7 6.8 26.1 5.1 6.3 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KFX86918.1 - 4.7 6.9 16.4 8 6.1 11.3 1.4 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 KFX86918.1 - 6.9 5.5 8.3 10 4.9 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0052 PF01933.13 KFX86918.1 - 7.2 5.8 6.2 7.4 5.7 3.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0052 Herpes_glycop_H PF02489.11 KFX86919.1 - 0.0066 14.5 0.0 0.0073 14.3 0.0 1.0 1 0 0 1 1 1 1 Herpesvirus glycoprotein H DEAD PF00270.24 KFX86920.1 - 1.2e-42 145.2 0.0 1.8e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX86920.1 - 6.8e-24 83.5 0.1 1.8e-23 82.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CoA_trans PF01144.18 KFX86921.1 - 2.1e-99 331.0 2.1 1.3e-61 207.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Nrap PF03813.9 KFX86922.1 - 0 1125.9 0.0 0 1125.7 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 KFX86923.1 - 9.6e-29 99.8 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SMC_N PF02463.14 KFX86923.1 - 2.9e-24 85.5 0.9 5.1e-24 84.7 0.6 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX86923.1 - 4.2e-07 30.4 47.8 4.2e-07 30.4 33.2 5.4 2 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX86923.1 - 2.4e-06 27.7 0.5 2.4e-05 24.4 0.4 2.3 2 0 0 2 2 2 1 AAA domain SMC_hinge PF06470.8 KFX86923.1 - 0.0002 21.3 0.0 0.00081 19.3 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 KFX86923.1 - 0.00024 20.5 0.1 0.00082 18.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KFX86923.1 - 0.0025 16.9 12.1 0.0086 15.1 8.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain IncA PF04156.9 KFX86923.1 - 0.0047 16.5 2.4 0.0047 16.5 1.7 6.2 4 1 1 5 5 5 1 IncA protein Lectin_N PF03954.9 KFX86923.1 - 1 8.7 12.3 1.4 8.2 0.0 3.8 3 1 0 4 4 4 0 Hepatic lectin, N-terminal domain Pkinase PF00069.20 KFX86924.1 - 3.8e-27 95.0 0.0 5.9e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86924.1 - 1e-05 24.7 0.3 0.00032 19.8 0.2 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L5_C PF00673.16 KFX86924.1 - 0.35 10.6 1.4 7.1 6.4 0.4 2.6 2 1 1 3 3 3 0 ribosomal L5P family C-terminus Rad17 PF03215.10 KFX86925.1 - 1.1e-58 199.2 0.0 3.5e-58 197.5 0.0 1.7 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KFX86925.1 - 0.0008 19.6 0.1 0.0027 17.9 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX86925.1 - 0.0018 17.9 0.8 0.0052 16.4 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KFX86925.1 - 0.0024 18.0 0.0 0.0076 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 KFX86925.1 - 0.0086 15.6 0.2 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFX86925.1 - 0.011 15.4 0.2 0.037 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFX86925.1 - 0.019 15.7 0.0 0.057 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFX86925.1 - 0.05 12.6 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KFX86925.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX86925.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFX86925.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFX86925.1 - 0.16 11.6 0.3 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFX86925.1 - 0.2 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF853 PF05872.7 KFX86925.1 - 2.5 6.3 6.4 0.16 10.3 0.2 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Pneumo_att_G PF05539.6 KFX86925.1 - 3.7 6.8 13.7 6.5 6.0 9.5 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G GFO_IDH_MocA PF01408.17 KFX86926.1 - 5.2e-24 85.0 0.0 1.1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KFX86926.1 - 0.0027 18.0 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KFX86926.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 KFX86927.1 - 4.5e-72 242.5 0.0 8.4e-72 241.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 KFX86927.1 - 1.8e-67 227.8 0.0 2.6e-67 227.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KFX86927.1 - 1.8e-60 204.9 0.4 3e-60 204.2 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFX86927.1 - 4.3e-54 182.9 0.0 2.4e-53 180.5 0.0 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KFX86927.1 - 2.8e-45 154.2 0.2 3.7e-44 150.5 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KFX86927.1 - 3.3e-44 151.2 0.0 5.1e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFX86927.1 - 4.1e-38 129.8 0.1 1.1e-37 128.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFX86927.1 - 1.3e-17 64.0 0.0 5.9e-17 61.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFX86927.1 - 6.9e-16 57.9 0.2 2.3e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFX86927.1 - 1.7e-12 47.3 0.0 1e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86927.1 - 5.8e-12 45.4 0.0 1.5e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFX86927.1 - 2.7e-11 44.4 0.0 1.7e-10 41.8 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KFX86927.1 - 1.1e-09 38.6 0.0 4.9e-09 36.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFX86927.1 - 4.1e-09 36.5 0.0 1.4e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KFX86927.1 - 1.2e-08 35.4 0.0 7.3e-08 32.9 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX86927.1 - 4e-05 22.8 0.0 8.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KFX86927.1 - 0.00041 19.1 0.0 0.00075 18.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 KFX86927.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 KFX86927.1 - 0.0029 16.6 0.0 0.0069 15.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 KFX86927.1 - 0.05 12.6 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Polysacc_synt_2 PF02719.10 KFX86927.1 - 0.16 10.8 0.0 0.32 9.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.14 KFX86928.1 - 5.6e-54 183.3 0.0 7.1e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX86928.1 - 5.9e-30 104.4 0.0 1.4e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX86928.1 - 3.1e-08 32.9 0.0 2.9e-05 23.1 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX86928.1 - 4.2e-07 29.1 0.0 0.00016 20.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KFX86928.1 - 8.3e-06 26.0 0.0 0.037 14.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX86928.1 - 4.6e-05 22.5 0.1 7.6e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KFX86928.1 - 0.00022 20.4 0.1 0.00045 19.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFX86928.1 - 0.00023 21.1 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX86928.1 - 0.00023 21.1 0.0 0.00065 19.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX86928.1 - 0.0028 16.2 0.2 0.006 15.1 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 KFX86928.1 - 0.0034 16.0 0.1 0.005 15.5 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 KFX86928.1 - 0.0039 16.9 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFX86928.1 - 0.026 13.4 0.0 0.76 8.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.20 KFX86929.1 - 9.8e-10 38.5 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX86929.1 - 0.00032 20.2 0.0 0.00078 18.9 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX86929.1 - 0.00045 19.5 0.0 0.00079 18.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX86929.1 - 0.00075 19.5 0.1 0.0018 18.3 0.0 1.7 2 1 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 KFX86929.1 - 0.0092 15.7 0.1 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 KFX86929.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 KFX86929.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX86929.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KFX86929.1 - 0.079 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pro-kuma_activ PF09286.6 KFX86930.1 - 7.5e-34 116.8 0.0 1.4e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KFX86930.1 - 2.7e-09 36.5 0.0 5.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Subtilase family DUF1304 PF06993.7 KFX86933.1 - 3.3e-39 133.1 3.5 3.6e-39 132.9 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) DsbD_2 PF13386.1 KFX86933.1 - 0.47 10.1 6.5 0.6 9.8 4.5 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Ank_2 PF12796.2 KFX86934.1 - 6e-20 71.3 0.0 8.6e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFX86934.1 - 2.4e-18 64.4 0.0 8.7e-05 22.4 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.25 KFX86934.1 - 1.3e-17 62.6 0.4 2.3e-06 27.1 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KFX86934.1 - 1.5e-12 47.6 0.0 3.2e-07 30.6 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX86934.1 - 7.4e-12 45.1 0.2 0.00052 20.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) HET PF06985.6 KFX86935.1 - 1.6e-19 70.4 1.9 2.4e-15 56.8 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FB_lectin PF07367.6 KFX86935.1 - 0.13 11.8 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Fungal fruit body lectin FA_desaturase PF00487.19 KFX86937.1 - 1.8e-39 135.7 22.0 2.9e-39 135.0 15.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFX86937.1 - 6e-10 38.7 0.0 1.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3821 PF12863.2 KFX86937.1 - 0.15 11.6 0.1 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) ASXH PF13919.1 KFX86938.1 - 5.2e-27 94.3 0.6 8.5e-27 93.6 0.4 1.3 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 KFX86939.1 - 1.5e-25 88.5 0.3 2.6e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFX86939.1 - 7.9e-16 57.4 0.0 1.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF760 PF05542.6 KFX86939.1 - 0.062 13.4 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF760) DUF1664 PF07889.7 KFX86939.1 - 0.089 12.5 0.4 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 KFX86939.1 - 0.4 9.6 1.5 12 4.9 0.1 2.8 2 1 1 3 3 3 0 E1-E2 ATPase Sirohm_synth_C PF14823.1 KFX86939.1 - 0.41 9.9 2.5 2.6 7.4 0.5 2.7 2 1 1 3 3 3 0 Sirohaem biosynthesis protein C-terminal Aminotran_3 PF00202.16 KFX86940.1 - 2.3e-41 141.8 0.0 2.6e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HA2 PF04408.18 KFX86941.1 - 2.7e-18 65.8 0.0 8.9e-18 64.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX86941.1 - 1.2e-14 53.8 0.0 7.3e-13 48.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KFX86941.1 - 1.7e-10 40.7 0.0 3.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KFX86941.1 - 2.4e-07 30.4 0.1 5.8e-06 25.9 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX86941.1 - 0.0012 18.9 0.0 0.0069 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX86941.1 - 0.0079 15.1 0.2 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KFX86941.1 - 0.035 13.5 0.4 0.08 12.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 KFX86941.1 - 0.047 13.5 1.3 8 6.2 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KFX86941.1 - 0.056 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 KaiC Lin-8 PF03353.10 KFX86941.1 - 5.5 6.1 13.6 1.2e+02 1.8 0.0 2.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Glypican PF01153.14 KFX86941.1 - 8.3 4.8 7.2 15 4.0 5.0 1.3 1 0 0 1 1 1 0 Glypican Preseq_ALAS PF09029.5 KFX86942.1 - 0.099 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Shikimate_DH PF01488.15 KFX86942.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Transcrip_reg PF01709.15 KFX86943.1 - 1.1e-53 181.7 0.0 1.6e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator DIOX_N PF14226.1 KFX86943.1 - 1.1e-22 80.6 0.0 7.3e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX86943.1 - 1.8e-18 66.6 0.0 3.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HEAT_2 PF13646.1 KFX86944.1 - 4e-13 49.4 4.8 0.0092 16.2 0.0 7.4 6 2 3 9 9 9 4 HEAT repeats HEAT PF02985.17 KFX86944.1 - 7.8e-07 28.6 28.4 0.22 11.7 0.0 11.7 13 0 0 13 13 13 2 HEAT repeat CLASP_N PF12348.3 KFX86944.1 - 0.00096 18.5 2.7 0.6 9.4 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFX86944.1 - 0.011 16.0 0.0 1 9.7 0.0 4.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 KFX86944.1 - 0.011 15.7 0.6 3.1 7.9 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 KFX86944.1 - 0.67 10.5 16.7 15 6.1 0.0 7.9 8 1 1 9 9 9 0 HEAT-like repeat DUF2897 PF11446.3 KFX86945.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PAP_PilO PF06864.7 KFX86945.1 - 0.062 11.6 0.1 0.086 11.1 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Chordopox_A33R PF05966.7 KFX86945.1 - 0.14 10.9 0.0 0.32 9.7 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Shisa PF13908.1 KFX86945.1 - 0.15 12.2 0.6 0.32 11.1 0.2 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator FAP PF07174.6 KFX86945.1 - 0.57 9.4 10.7 0.84 8.8 7.4 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Methyltransf_12 PF08242.7 KFX86946.1 - 6.9e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX86946.1 - 1.1e-06 28.4 0.0 1.5e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX86946.1 - 8.9e-06 26.1 0.1 3.4e-05 24.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86946.1 - 6e-05 22.6 0.0 9.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86946.1 - 6.3e-05 23.5 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX86946.1 - 0.00024 21.4 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX86946.1 - 0.00045 20.2 0.0 0.00079 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX86946.1 - 0.0012 18.2 0.0 0.0039 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain GFA PF04828.9 KFX86947.1 - 1.2e-14 53.9 4.7 4.7e-07 29.6 0.2 2.6 3 0 0 3 3 2 2 Glutathione-dependent formaldehyde-activating enzyme Plant_zn_clust PF10533.4 KFX86947.1 - 0.03 13.9 1.5 0.92 9.1 0.0 2.5 2 0 0 2 2 2 0 Plant zinc cluster domain zf-ribbon_3 PF13248.1 KFX86947.1 - 0.041 13.0 13.0 0.2 10.8 0.0 4.3 5 0 0 5 5 5 0 zinc-ribbon domain zf-4CXXC_R1 PF10497.4 KFX86947.1 - 0.065 13.3 4.2 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Desulfoferrod_N PF06397.7 KFX86947.1 - 0.12 11.7 0.4 0.12 11.7 0.3 3.5 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain zf-CSL PF05207.8 KFX86947.1 - 0.18 11.3 14.9 0.08 12.4 1.0 3.3 4 0 0 4 4 4 0 CSL zinc finger zf-NADH-PPase PF09297.6 KFX86947.1 - 0.22 11.0 11.3 0.28 10.7 0.1 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 KFX86947.1 - 1.4 8.8 11.6 7.8 6.4 0.0 3.3 3 1 0 3 3 3 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 KFX86947.1 - 1.9 8.3 7.8 2.6 7.9 0.3 3.4 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.1 KFX86947.1 - 5.3 6.6 18.6 0.27 10.7 0.2 4.3 4 1 0 4 4 4 0 zinc-ribbon domain Cys_rich_CWC PF14375.1 KFX86947.1 - 5.9 6.8 9.3 6.3 6.7 0.2 2.7 3 0 0 3 3 3 0 Cysteine-rich CWC MFS_1 PF07690.11 KFX86948.1 - 6.3e-29 100.7 23.3 7.5e-20 70.9 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX86948.1 - 0.0041 16.8 2.5 0.019 14.7 1.7 2.2 1 1 0 1 1 1 1 MFS_1 like family adh_short PF00106.20 KFX86949.1 - 1.2e-14 54.5 0.0 1.6e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX86949.1 - 2.3e-08 34.1 0.0 2.9e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX86949.1 - 2.2e-07 30.7 0.0 3.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX86949.1 - 5e-05 22.8 0.0 7.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX86949.1 - 0.02 14.8 0.0 0.098 12.6 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Zn_clus PF00172.13 KFX86950.1 - 1.4e-08 34.4 11.0 2.7e-08 33.5 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX86950.1 - 0.022 13.6 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain TENA_THI-4 PF03070.11 KFX86951.1 - 5.4e-08 32.8 0.0 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 2 TENA/THI-4/PQQC family MARVEL PF01284.18 KFX86952.1 - 1.8e-23 82.9 19.2 2.3e-23 82.6 13.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1422 PF07226.6 KFX86952.1 - 0.15 11.7 3.8 0.26 11.0 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF2206 PF09971.4 KFX86952.1 - 0.34 9.6 3.1 0.36 9.5 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) SecD_SecF PF02355.11 KFX86952.1 - 3.6 6.7 8.4 0.24 10.5 0.5 2.5 2 1 1 3 3 3 0 Protein export membrane protein Glyco_hydro_43 PF04616.9 KFX86954.1 - 3.9e-30 104.9 3.4 1.7e-18 66.7 0.3 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 KFX86954.1 - 0.33 9.6 3.2 12 4.4 0.0 3.6 3 2 1 4 4 4 0 Levansucrase/Invertase Methyltransf_11 PF08241.7 KFX86955.1 - 1.6e-16 60.5 0.0 2.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX86955.1 - 7.6e-14 51.9 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86955.1 - 1.6e-13 50.4 0.0 2.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86955.1 - 3.7e-12 46.8 0.0 6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX86955.1 - 3.3e-10 39.9 0.0 5.6e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX86955.1 - 6.7e-09 36.1 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX86955.1 - 2.2e-08 34.1 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX86955.1 - 1.6e-06 27.4 0.0 6.9e-06 25.3 0.0 1.8 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFX86955.1 - 3.7e-06 26.4 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KFX86955.1 - 2.2e-05 23.6 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KFX86955.1 - 0.00022 20.6 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KFX86955.1 - 0.0019 17.2 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KFX86955.1 - 0.0054 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.6 KFX86955.1 - 0.0065 15.1 0.0 0.0085 14.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 KFX86955.1 - 0.065 12.3 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FokI_C PF02980.11 KFX86955.1 - 0.093 12.3 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain Pox_MCEL PF03291.11 KFX86955.1 - 0.15 10.9 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme ADH_N PF08240.7 KFX86956.1 - 6.8e-21 74.0 0.2 1.5e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX86956.1 - 3.7e-11 42.6 0.1 8.2e-10 38.3 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX86956.1 - 9.6e-07 28.1 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KFX86956.1 - 0.0001 21.9 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KFX86956.1 - 0.00013 22.0 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KFX86956.1 - 0.0055 16.5 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KFX86956.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2346 PF09803.4 KFX86957.1 - 0.00089 19.0 3.0 0.0099 15.7 1.8 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2346) ECH PF00378.15 KFX86958.1 - 4.5e-20 71.8 0.0 5.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family cwf21 PF08312.7 KFX86959.1 - 1.3e-16 60.1 7.8 1.3e-16 60.1 5.4 2.0 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.6 KFX86959.1 - 0.064 12.5 0.3 0.09 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) VIT1 PF01988.14 KFX86959.1 - 4.7 6.6 5.9 8.2 5.8 4.1 1.5 1 1 0 1 1 1 0 VIT family D123 PF07065.9 KFX86960.1 - 3.3e-79 266.0 0.0 8e-79 264.8 0.0 1.6 1 1 0 1 1 1 1 D123 DUF3684 PF12449.3 KFX86961.1 - 0 1314.4 0.0 0 1314.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KFX86961.1 - 0.00014 21.4 0.0 0.00098 18.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med6 PF04934.9 KFX86962.1 - 7.3e-45 151.9 0.0 1e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component RabGAP-TBC PF00566.13 KFX86963.1 - 6e-37 127.1 2.8 1.2e-36 126.2 2.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KFX86963.1 - 5e-08 32.4 0.0 7.5e-05 22.1 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3548) DUF2360 PF10152.4 KFX86963.1 - 0.05 13.8 0.3 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MMtag PF10159.4 KFX86964.1 - 9.8e-29 99.2 4.4 9.8e-29 99.2 3.0 2.0 2 0 0 2 2 2 1 Kinase phosphorylation protein zf-C2H2_4 PF13894.1 KFX86965.1 - 0.0098 16.1 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX86965.1 - 0.025 14.8 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type TrmE_N PF10396.4 KFX86968.1 - 2.3e-33 114.5 0.0 4.4e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KFX86968.1 - 4.1e-19 68.7 0.1 1.1e-18 67.4 0.1 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KFX86968.1 - 2e-17 63.2 0.0 4.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFX86968.1 - 8.4e-06 25.6 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 KFX86968.1 - 0.00044 19.5 0.0 0.00084 18.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFX86968.1 - 0.0025 18.3 0.0 0.0082 16.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFX86968.1 - 0.0046 16.4 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFX86968.1 - 0.085 13.1 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 KFX86968.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_L28e PF01778.12 KFX86969.1 - 9.5e-33 113.0 0.9 2e-32 112.0 0.6 1.6 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KFX86969.1 - 1.5e-23 82.7 17.7 1.5e-23 82.7 12.3 2.8 2 1 0 2 2 2 1 Mak16 protein C-terminal region Mso1_Sec1_bdg PF14475.1 KFX86969.1 - 1.1e-18 66.3 0.0 2.6e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 BUD22 PF09073.5 KFX86969.1 - 0.0029 16.7 19.7 0.0052 15.9 13.7 1.4 1 0 0 1 1 1 1 BUD22 Daxx PF03344.10 KFX86969.1 - 0.03 12.8 13.8 0.048 12.1 9.6 1.3 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 KFX86969.1 - 0.64 8.3 21.0 1.1 7.5 14.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KFX86969.1 - 0.85 7.4 25.7 1.2 6.9 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 KFX86969.1 - 6.5 6.2 22.1 0.1 12.1 9.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Elong_Iki1 PF10483.4 KFX86970.1 - 1.2e-84 284.0 0.0 1.4e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 KFX86971.1 - 1.7e-22 80.0 49.5 1.7e-22 80.0 34.3 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) AA_permease_2 PF13520.1 KFX86972.1 - 5.7e-22 77.8 22.4 6.8e-22 77.5 15.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX86972.1 - 2.9e-07 29.1 15.7 3.5e-07 28.9 10.9 1.1 1 0 0 1 1 1 1 Amino acid permease zf-UBR PF02207.15 KFX86973.1 - 1.1e-15 57.0 3.1 1.1e-15 57.0 2.2 2.9 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) ELFV_dehydrog PF00208.16 KFX86974.1 - 9.9e-22 77.7 0.0 1.7e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KFX86974.1 - 1.7e-15 55.6 0.0 2.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KFX86974.1 - 0.016 14.8 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain FCD PF07729.7 KFX86976.1 - 0.056 13.7 0.2 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 FCD domain EF-hand_7 PF13499.1 KFX86977.1 - 8.2e-29 99.5 10.2 1.1e-12 47.8 0.5 3.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KFX86977.1 - 1.9e-24 83.0 11.7 3.8e-08 32.0 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFX86977.1 - 7.2e-23 78.3 4.0 8.1e-06 25.3 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KFX86977.1 - 1.7e-16 58.7 14.2 2.6e-05 23.3 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFX86977.1 - 1.2e-14 53.5 11.1 1.4e-05 24.6 0.7 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KFX86977.1 - 6.3e-09 35.5 7.4 0.0015 18.1 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFX86977.1 - 0.00035 20.4 0.6 0.031 14.2 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KFX86977.1 - 0.0012 18.8 1.2 0.23 11.5 0.1 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 KFX86977.1 - 0.0035 16.0 0.6 0.28 9.7 0.1 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1679) EF-hand_10 PF14788.1 KFX86977.1 - 0.0063 16.1 3.1 0.22 11.2 0.1 3.8 4 0 0 4 4 4 1 EF hand EF-hand_2 PF09068.6 KFX86977.1 - 0.015 15.3 0.2 0.9 9.6 0.0 2.8 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 KFX86977.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 Med4 PF10018.4 KFX86978.1 - 3e-42 144.1 5.7 4.9e-42 143.4 4.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TMEM247 PF15444.1 KFX86978.1 - 0.0076 16.0 2.3 0.016 15.0 1.6 1.5 1 0 0 1 1 1 1 Transmembrane protein 247 DUF1682 PF07946.9 KFX86978.1 - 0.89 8.3 8.2 1.2 7.9 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Sas10_Utp3 PF04000.10 KFX86979.1 - 5.8e-17 61.6 1.7 1.1e-16 60.7 1.2 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RcsC PF09456.5 KFX86979.1 - 0.14 11.8 0.6 0.25 11.0 0.4 1.4 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) EMP70 PF02990.11 KFX86980.1 - 2.3e-192 640.1 0.8 2.3e-192 640.1 0.6 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 NfeD PF01957.13 KFX86980.1 - 0.016 15.3 0.0 0.016 15.3 0.0 4.7 2 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding Pectate_lyase PF03211.8 KFX86981.1 - 3.6e-77 258.6 6.4 5.1e-77 258.1 4.4 1.2 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 KFX86982.1 - 3.3e-36 124.7 25.7 3.3e-36 124.7 17.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 KFX86982.1 - 1.1 9.0 6.7 6.9 6.3 0.3 2.9 3 1 0 3 3 3 0 Anti-sigma-K factor rskA Arylsulfotran_2 PF14269.1 KFX86983.1 - 1.7e-21 76.6 0.0 2.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFX86983.1 - 6.4e-21 74.4 0.0 7.3e-10 37.9 0.0 3.0 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 KFX86983.1 - 1.1e-05 25.0 0.0 0.00015 21.3 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain Transferase PF02458.10 KFX86984.1 - 1.4e-06 27.0 0.0 3.3e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Transferase family Peptidase_M1 PF01433.15 KFX86986.1 - 4.6e-107 358.4 0.0 5.9e-107 358.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFX86986.1 - 2.4e-52 178.2 0.2 3.2e-52 177.7 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFX86986.1 - 1.2e-13 51.2 0.4 2.5e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF4198 PF10670.4 KFX86986.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) NAD_binding_4 PF07993.7 KFX86987.1 - 1.6e-26 92.7 0.0 2.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFX86987.1 - 5.7e-15 55.3 0.0 1.7e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX86987.1 - 0.031 13.1 0.0 10 4.8 0.0 3.0 3 0 0 3 3 3 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFX86987.1 - 0.035 14.1 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding Gaa1 PF04114.9 KFX86987.1 - 0.085 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component adh_short PF00106.20 KFX86987.1 - 0.12 12.2 1.6 0.14 12.0 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX86987.1 - 0.16 10.8 0.3 1.5 7.6 0.0 2.4 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein DUF302 PF03625.9 KFX86988.1 - 1.9e-05 24.1 0.0 3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 Amidase PF01425.16 KFX86989.1 - 7e-10 38.3 0.0 8.1e-10 38.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Abhydrolase_6 PF12697.2 KFX86990.1 - 1.3e-26 93.8 0.1 1.7e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX86990.1 - 2.3e-18 66.5 0.3 8.4e-18 64.7 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX86990.1 - 3.3e-11 43.1 0.1 2.4e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KFX86990.1 - 1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KFX86990.1 - 0.00011 21.5 0.0 0.031 13.5 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 KFX86990.1 - 0.00067 18.9 0.0 0.059 12.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 KFX86990.1 - 0.0088 15.6 0.1 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.15 KFX86990.1 - 0.0093 15.4 0.1 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.3 KFX86990.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 KFX86990.1 - 0.041 12.3 0.1 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family FSH1 PF03959.8 KFX86990.1 - 0.097 12.1 0.0 0.81 9.0 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2048 PF09752.4 KFX86990.1 - 0.12 11.2 0.1 0.36 9.6 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Glyco_hydro_10 PF00331.15 KFX86991.1 - 2.2e-101 339.1 0.1 2.7e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 ADH_zinc_N_2 PF13602.1 KFX86991.1 - 3.8e-09 37.4 0.1 1.4e-07 32.4 0.0 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX86991.1 - 0.0033 16.9 0.0 0.0085 15.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_42 PF02449.10 KFX86991.1 - 0.028 13.5 0.1 0.13 11.3 0.0 1.9 1 1 1 2 2 2 0 Beta-galactosidase MFS_1 PF07690.11 KFX86992.1 - 3.3e-34 118.1 54.3 6.4e-34 117.2 36.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX86992.1 - 5.4e-22 77.7 24.0 7.3e-22 77.3 16.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX86992.1 - 7.9e-13 47.7 19.2 7.9e-13 47.7 13.3 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter Ank_2 PF12796.2 KFX86993.1 - 7.9e-15 54.9 0.0 3.6e-06 27.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX86993.1 - 9.1e-12 44.1 0.0 0.4 10.5 0.0 6.2 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFX86993.1 - 5.1e-11 42.7 0.0 0.00015 22.2 0.0 5.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX86993.1 - 2e-10 39.8 0.0 1.2 9.5 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 KFX86993.1 - 7e-06 26.1 0.0 1.1 9.6 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeats (many copies) PLA2_B PF01735.13 KFX86995.1 - 1.3e-24 86.2 0.0 4.2e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Rotamase_2 PF13145.1 KFX86995.1 - 0.024 15.2 0.4 0.024 15.2 0.3 3.3 3 0 0 3 3 3 0 PPIC-type PPIASE domain RE_NgoPII PF09521.5 KFX86995.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NgoPII restriction endonuclease DUF1214 PF06742.6 KFX86996.1 - 1.6e-09 38.1 0.7 0.00051 20.4 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1214) GPI-anchored PF10342.4 KFX86996.1 - 0.026 14.9 1.1 0.23 11.9 0.1 2.6 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_4 PF13754.1 KFX86996.1 - 0.053 13.8 4.0 0.73 10.1 0.4 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF2670 PF10875.3 KFX86996.1 - 0.069 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) He_PIG PF05345.7 KFX86996.1 - 0.18 11.8 3.3 2.7 8.0 0.2 2.9 2 0 0 2 2 2 0 Putative Ig domain Fungal_trans PF04082.13 KFX86997.1 - 7.2e-64 215.1 0.2 1.2e-63 214.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX86997.1 - 8.7e-07 28.9 9.9 0.00016 21.7 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX86997.1 - 7.2e-06 25.9 9.6 0.00028 21.0 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX86997.1 - 0.0032 17.6 1.3 0.0032 17.6 0.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain CTDII PF01556.13 KFX86998.1 - 1.6e-26 91.9 1.1 2.7e-21 75.2 0.1 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KFX86998.1 - 1.5e-22 79.0 1.7 2.8e-22 78.2 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain SAP30_Sin3_bdg PF13867.1 KFX86998.1 - 1.5e-12 47.1 0.1 1.8e-11 43.7 0.1 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ_CXXCXGXG PF00684.14 KFX86998.1 - 1.2e-10 41.2 19.9 2.8e-10 40.1 13.8 1.7 1 0 0 1 1 1 1 DnaJ central domain Aminotran_5 PF00266.14 KFX87000.1 - 1.1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V WW PF00397.21 KFX87003.1 - 1.2e-07 31.4 1.5 2.9e-07 30.2 1.0 1.6 1 0 0 1 1 1 1 WW domain ECM1 PF05782.6 KFX87003.1 - 1.2 7.7 8.2 1.5 7.4 5.7 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Voldacs PF03517.8 KFX87004.1 - 5.3e-28 97.5 0.0 5.3e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Peptidase_M18 PF02127.10 KFX87005.1 - 1.3e-126 422.6 0.0 1.7e-126 422.2 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) tRNA-synt_1e PF01406.14 KFX87005.1 - 8.9e-116 386.2 0.0 1.6e-115 385.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KFX87005.1 - 3.7e-06 25.8 0.1 0.077 11.6 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KFX87005.1 - 0.00042 20.5 0.0 0.00042 20.5 0.0 1.9 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 KFX87005.1 - 0.051 12.2 4.6 0.23 10.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF1777 PF08648.7 KFX87005.1 - 0.46 10.2 5.4 0.9 9.2 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CENP-C_C PF11699.3 KFX87007.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.7 KFX87007.1 - 0.0043 16.3 0.2 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) zf-C2H2 PF00096.21 KFX87007.1 - 0.011 16.0 0.9 0.037 14.3 0.6 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX87007.1 - 0.012 15.8 0.3 0.032 14.5 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Cupin_2 PF07883.6 KFX87007.1 - 0.059 12.8 1.3 0.075 12.5 0.1 1.8 2 0 0 2 2 2 0 Cupin domain IPP-2 PF04979.9 KFX87008.1 - 1.3e-09 38.3 12.2 3.5e-07 30.5 1.3 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) NmrA PF05368.8 KFX87009.1 - 9e-20 70.9 0.1 1.1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX87009.1 - 1.7e-07 31.4 0.2 5.8e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KFX87009.1 - 0.00033 20.6 0.1 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX87009.1 - 0.00073 19.0 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFX87009.1 - 0.0087 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KFX87009.1 - 0.051 12.4 0.2 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 KFX87010.1 - 5.5e-42 142.9 0.0 7.4e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX87010.1 - 4.8e-11 42.2 0.0 6.6e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX87010.1 - 2.9e-09 36.9 0.1 1.4e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX87010.1 - 0.00029 21.1 0.2 0.00053 20.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KFX87010.1 - 0.0028 18.1 0.1 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.16 KFX87010.1 - 0.011 15.9 0.0 0.083 13.0 0.0 2.2 2 0 0 2 2 2 0 Radical SAM superfamily IlvN PF07991.7 KFX87010.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 KFX87010.1 - 0.056 13.4 0.3 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 KFX87010.1 - 0.12 11.9 0.2 0.47 10.0 0.1 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX87010.1 - 0.37 10.5 1.9 8.5 6.0 1.3 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lipase_GDSL PF00657.17 KFX87011.1 - 2.2e-14 53.8 1.3 2.9e-14 53.4 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX87011.1 - 1.1e-13 51.6 3.5 1.5e-13 51.2 2.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family EXS PF03124.9 KFX87012.1 - 6.5e-96 321.3 25.8 8.1e-96 321.0 17.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KFX87012.1 - 5e-57 193.7 1.0 2.4e-55 188.2 0.0 2.6 2 1 0 2 2 2 1 SPX domain An_peroxidase PF03098.10 KFX87013.1 - 1.4e-95 320.6 0.0 2e-93 313.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KFX87013.1 - 1.2e-11 43.7 0.0 7.9e-08 31.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 tRNA_int_endo PF01974.12 KFX87014.1 - 2e-21 75.5 0.2 4.2e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KFX87014.1 - 7.4e-06 25.4 0.0 0.006 16.1 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF3759 PF12585.3 KFX87017.1 - 4.7e-37 125.7 9.6 6.7e-37 125.2 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) CoaE PF01121.15 KFX87018.1 - 4.5e-43 146.7 0.0 6.9e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KFX87018.1 - 0.041 14.6 0.1 0.14 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_M16 PF00675.15 KFX87019.1 - 9.1e-34 116.3 1.2 6.6e-33 113.5 0.1 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFX87019.1 - 3.4e-31 108.3 0.9 3.1e-20 72.6 0.0 3.2 4 0 0 4 4 4 2 Peptidase M16 inactive domain zf-CCHC PF00098.18 KFX87020.1 - 2.8e-07 30.1 1.9 5.4e-07 29.2 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Nop53 PF07767.6 KFX87020.1 - 0.0013 17.8 7.2 0.0013 17.8 5.0 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) zf-CCHC_2 PF13696.1 KFX87020.1 - 0.027 13.9 0.8 0.055 12.9 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Cwf_Cwc_15 PF04889.7 KFX87020.1 - 0.027 14.1 20.7 0.059 13.0 14.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CCHC_3 PF13917.1 KFX87020.1 - 0.044 13.5 0.3 0.086 12.5 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.9 KFX87020.1 - 0.13 10.2 9.8 0.19 9.7 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein MPP6 PF10175.4 KFX87020.1 - 0.71 10.2 12.8 0.95 9.8 0.0 3.4 4 0 0 4 4 4 0 M-phase phosphoprotein 6 zf-CHCC PF10276.4 KFX87021.1 - 2.6e-16 59.1 1.9 4.5e-16 58.4 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain I_LWEQ PF01608.12 KFX87021.1 - 0.2 11.5 1.8 0.28 11.0 1.3 1.2 1 0 0 1 1 1 0 I/LWEQ domain Glyco_tranf_2_3 PF13641.1 KFX87022.1 - 6.9e-13 48.9 0.0 1.7e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFX87022.1 - 1.2e-12 47.4 0.0 2.3e-08 33.5 0.0 3.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFX87022.1 - 0.00027 20.6 0.0 0.0051 16.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Toxin_61 PF15538.1 KFX87022.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative toxin 61 HCO3_cotransp PF00955.16 KFX87023.1 - 1.8e-66 224.8 14.6 5.8e-39 134.1 4.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family Glyco_hydro_cc PF11790.3 KFX87023.1 - 1e-14 54.5 0.0 2.2e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core MOSC_N PF03476.11 KFX87024.1 - 4.5e-13 48.9 0.0 1.1e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFX87024.1 - 5e-11 42.2 0.0 8.4e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain zf-RING_2 PF13639.1 KFX87025.1 - 1.5e-13 50.3 5.7 2.8e-13 49.4 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFX87025.1 - 1.6e-10 40.5 0.0 3.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KFX87025.1 - 9.1e-09 35.2 5.3 9.1e-09 35.2 3.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX87025.1 - 1e-08 34.6 2.7 1.9e-08 33.8 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX87025.1 - 1.3e-08 34.8 2.9 3e-08 33.6 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFX87025.1 - 1.7e-07 30.7 3.1 1.7e-07 30.7 2.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX87025.1 - 3e-07 30.0 2.2 6.3e-07 29.0 1.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KFX87025.1 - 0.001 18.8 0.8 0.0024 17.6 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRP14 PF15459.1 KFX87025.1 - 0.0077 16.2 1.1 0.0077 16.2 0.8 2.2 2 0 0 2 2 1 1 60S ribosome biogenesis protein Rrp14 zf-RING_UBOX PF13445.1 KFX87025.1 - 0.14 11.9 2.6 0.31 10.7 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 KFX87025.1 - 0.14 12.1 3.3 0.27 11.2 2.3 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFX87025.1 - 0.16 11.9 2.1 0.41 10.6 1.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 KFX87025.1 - 0.23 11.4 3.5 0.45 10.5 2.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 KFX87025.1 - 0.36 10.4 2.4 0.71 9.5 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFX87025.1 - 7.1 6.5 10.9 0.16 11.8 2.5 2.1 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING ACPS PF01648.15 KFX87026.1 - 7.5e-08 32.1 0.0 4.9e-07 29.5 0.0 2.3 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_61 PF03443.9 KFX87027.1 - 2e-51 174.9 0.0 2.3e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4360 PF14273.1 KFX87028.1 - 2.7e-54 183.5 3.2 1.3e-53 181.4 2.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Rio2_N PF09202.6 KFX87029.1 - 1.1e-29 102.2 0.1 1.6e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 Rio2, N-terminal RIO1 PF01163.17 KFX87029.1 - 0.00025 20.4 0.0 0.00046 19.5 0.0 1.4 2 0 0 2 2 2 1 RIO1 family PC_rep PF01851.17 KFX87030.1 - 3.9e-22 77.1 13.7 3.1e-06 27.0 0.4 8.6 9 0 0 9 9 9 6 Proteasome/cyclosome repeat PPTA PF01239.17 KFX87031.1 - 0.041 13.2 3.5 0.082 12.2 2.4 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DNA_mis_repair PF01119.14 KFX87032.1 - 7.6e-33 112.5 0.1 1.7e-32 111.3 0.1 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFX87032.1 - 2e-15 56.6 0.0 4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFX87032.1 - 1.9e-09 37.1 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FYVE PF01363.16 KFX87033.1 - 0.33 10.8 7.3 0.49 10.3 4.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger DUF2256 PF10013.4 KFX87033.1 - 0.69 9.7 3.8 0.84 9.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DHHA2 PF02833.9 KFX87034.1 - 1e-24 87.1 0.0 1.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KFX87034.1 - 7.8e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 DHH family FMO-like PF00743.14 KFX87035.1 - 1.4e-57 195.1 0.0 2e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX87035.1 - 9.2e-25 87.8 0.0 1.6e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AATase PF07247.7 KFX87035.1 - 3.9e-22 78.4 0.0 2.7e-21 75.7 0.0 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Pyr_redox_2 PF07992.9 KFX87035.1 - 4.9e-09 36.3 0.0 7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX87035.1 - 1.6e-07 31.2 0.0 4.1e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Condensation PF00668.15 KFX87035.1 - 7e-07 28.3 2.3 2.9e-06 26.3 0.7 2.2 2 1 0 2 2 2 1 Condensation domain K_oxygenase PF13434.1 KFX87035.1 - 2.2e-06 26.8 1.2 9e-05 21.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFX87035.1 - 3.1e-06 27.0 1.3 4.8e-05 23.1 0.0 3.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX87035.1 - 0.0003 21.1 0.0 0.034 14.5 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase WES_acyltransf PF03007.11 KFX87035.1 - 0.00038 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Thi4 PF01946.12 KFX87035.1 - 0.00073 18.6 0.0 0.002 17.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KFX87035.1 - 0.0036 16.2 0.0 0.0099 14.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KFX87035.1 - 0.0084 16.3 0.0 2.3 8.5 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX87035.1 - 0.032 13.3 0.0 0.9 8.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFX87035.1 - 0.15 11.3 0.0 0.76 9.1 0.0 2.2 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KFX87035.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KFX87035.1 - 0.16 12.0 0.0 3.1 7.9 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Spc97_Spc98 PF04130.8 KFX87036.1 - 9e-59 199.2 0.0 9.9e-58 195.7 0.0 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family ThiF PF00899.16 KFX87038.1 - 3.5e-49 166.1 0.1 1.8e-29 102.3 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KFX87038.1 - 1.3e-39 133.5 3.1 2e-26 91.3 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KFX87038.1 - 2.2e-35 121.5 0.0 1.3e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KFX87038.1 - 6e-23 79.9 1.1 2.2e-20 71.7 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KFX87038.1 - 0.053 13.6 0.2 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KFX87038.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Rad60-SLD_2 PF13881.1 KFX87039.1 - 8.9e-14 51.3 0.2 2.7e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFX87039.1 - 7.2e-07 28.5 0.0 1.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFX87039.1 - 0.00015 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain 7TMR-HDED PF07697.6 KFX87039.1 - 0.096 12.4 0.4 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 7TM-HD extracellular AMP-binding PF00501.23 KFX87040.1 - 5.8e-77 258.8 0.0 7.2e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX87040.1 - 1.5e-11 45.0 0.1 4.3e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 KFX87041.1 - 6.5e-22 78.3 0.0 2.1e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RPA_interact_C PF14768.1 KFX87041.1 - 0.008 16.5 1.4 0.021 15.2 1.0 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal AIRC PF00731.15 KFX87042.1 - 4.1e-58 194.9 2.0 9.5e-58 193.7 1.4 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KFX87042.1 - 4.4e-55 185.6 0.0 8.2e-55 184.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KFX87042.1 - 2e-11 43.9 0.0 3.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFX87042.1 - 2.2e-07 30.4 0.0 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Radical_SAM PF04055.16 KFX87042.1 - 0.0049 17.0 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 2 Radical SAM superfamily ATPgrasp_Ter PF15632.1 KFX87042.1 - 0.0079 14.9 0.0 0.034 12.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX87042.1 - 0.019 14.3 0.0 0.37 10.1 0.0 2.3 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 KFX87042.1 - 0.077 12.1 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain APH PF01636.18 KFX87043.1 - 3.4e-11 43.3 0.3 1.1e-10 41.7 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX87043.1 - 0.00023 20.5 0.0 0.003 16.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KFX87043.1 - 0.00032 20.3 0.0 0.00042 19.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFX87043.1 - 0.0012 17.9 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 KFX87043.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KFX87043.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Epimerase PF01370.16 KFX87044.1 - 8.9e-10 38.3 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX87044.1 - 2.6e-06 27.5 0.2 3.8e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX87044.1 - 3.6e-06 26.1 0.0 5.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFX87044.1 - 0.0011 17.7 0.0 0.0019 16.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX87044.1 - 0.0011 18.8 3.2 0.0021 18.0 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX87044.1 - 0.0061 16.2 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 KR domain PI3_PI4_kinase PF00454.22 KFX87045.1 - 1.9e-50 171.5 0.0 4.3e-50 170.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ank_2 PF12796.2 KFX87045.1 - 1.1e-49 166.6 0.0 9e-14 51.5 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) FAT PF02259.18 KFX87045.1 - 4.6e-41 140.9 7.4 8.6e-41 140.0 5.1 1.5 1 0 0 1 1 1 1 FAT domain Ank_5 PF13857.1 KFX87045.1 - 5.6e-34 115.4 0.3 8.5e-07 29.0 0.0 8.2 4 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX87045.1 - 3e-33 113.6 0.1 7.7e-06 26.2 0.0 7.8 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 KFX87045.1 - 2.3e-31 106.0 0.0 0.0031 17.2 0.0 10.8 10 0 0 10 10 10 5 Ankyrin repeat UME PF08064.8 KFX87045.1 - 1.9e-30 104.9 0.2 2.7e-29 101.2 0.0 3.1 2 0 0 2 2 2 1 UME (NUC010) domain Ank_3 PF13606.1 KFX87045.1 - 1.3e-26 89.9 0.0 0.0046 17.0 0.0 11.3 9 0 0 9 9 9 4 Ankyrin repeat NACHT PF05729.7 KFX87045.1 - 3.5e-12 46.2 0.0 1.3e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFX87045.1 - 9e-07 29.0 0.0 6.4e-06 26.2 0.0 2.6 1 0 0 1 1 1 1 AAA ATPase domain FATC PF02260.15 KFX87045.1 - 1.6e-06 27.4 0.0 5.1e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 FATC domain AAA_22 PF13401.1 KFX87045.1 - 8e-05 22.7 0.0 0.00066 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.9 KFX87045.1 - 0.00088 18.6 0.0 0.013 14.8 0.0 2.6 2 1 1 3 3 3 1 Putative serine esterase (DUF676) TPR_14 PF13428.1 KFX87045.1 - 0.032 14.8 0.7 26 5.8 0.1 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX87045.1 - 0.035 14.4 1.9 0.09 13.1 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat NTPase_1 PF03266.10 KFX87045.1 - 0.23 11.1 0.0 0.71 9.5 0.0 1.8 1 0 0 1 1 1 0 NTPase COX16 PF14138.1 KFX87046.1 - 9.7e-34 115.3 0.1 1.2e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DnaJ PF00226.26 KFX87046.1 - 0.027 14.2 0.1 0.82 9.4 0.1 2.3 2 0 0 2 2 2 0 DnaJ domain Acetyltransf_1 PF00583.19 KFX87047.1 - 1.1e-09 38.1 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX87047.1 - 1.8e-08 34.4 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX87047.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX87047.1 - 2.4e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX87047.1 - 6.1e-05 22.6 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFX87047.1 - 0.0034 17.2 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KFX87047.1 - 0.0039 16.7 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX87047.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase BcrAD_BadFG PF01869.15 KFX87049.1 - 4.1e-18 65.6 0.2 6.7e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.17 KFX87049.1 - 7.7e-06 25.5 1.4 3.9e-05 23.2 0.0 2.7 3 1 1 4 4 4 1 SIS domain SIS_2 PF13580.1 KFX87049.1 - 0.00015 21.5 0.1 0.0019 17.9 0.0 2.8 2 1 0 2 2 2 1 SIS domain Cas_csx3 PF09620.5 KFX87049.1 - 0.072 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) MFS_1 PF07690.11 KFX87050.1 - 7.1e-08 31.5 40.4 7.1e-08 31.5 28.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFX87050.1 - 2.3e-07 30.4 6.8 2.3e-07 30.4 4.7 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Beta-lactamase PF00144.19 KFX87051.1 - 8.1e-52 176.2 0.0 1.1e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX87051.1 - 0.00019 20.7 0.8 0.0018 17.5 0.1 2.5 2 1 1 3 3 3 1 D-alanyl-D-alanine carboxypeptidase DIM1 PF02966.11 KFX87052.1 - 1.3e-67 225.4 0.5 1.8e-67 224.9 0.3 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF218 PF02698.12 KFX87052.1 - 6.1e-28 97.2 0.0 9.2e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Thioredoxin_8 PF13905.1 KFX87052.1 - 0.084 12.9 0.2 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like DUF2439 PF10382.4 KFX87053.1 - 5.4e-26 90.6 0.1 1.2e-25 89.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Mid2 PF04478.7 KFX87059.1 - 0.0093 15.3 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.6 KFX87059.1 - 0.056 13.0 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Podoplanin VSP PF03302.8 KFX87059.1 - 1.3 7.5 18.3 0.046 12.3 2.9 2.3 1 1 1 2 2 2 0 Giardia variant-specific surface protein BAR_2 PF10455.4 KFX87061.1 - 3.2e-26 91.9 0.5 3.6e-26 91.7 0.4 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFX87061.1 - 9.1e-07 28.6 0.4 1.1e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KFX87061.1 - 0.0065 15.8 0.4 0.0089 15.4 0.3 1.2 1 0 0 1 1 1 1 Arfaptin-like domain TMF_TATA_bd PF12325.3 KFX87061.1 - 0.056 13.1 0.9 0.074 12.7 0.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YcbB PF08664.5 KFX87061.1 - 0.081 12.7 0.1 0.23 11.2 0.1 1.7 1 1 1 2 2 2 0 YcbB domain ING PF12998.2 KFX87061.1 - 0.085 13.1 0.8 0.13 12.5 0.6 1.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding HD_3 PF13023.1 KFX87063.1 - 3.4e-45 153.7 0.0 5.2e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 HD domain MAGE_N PF12440.3 KFX87064.1 - 0.14 12.4 2.5 0.23 11.7 1.7 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Ribosomal_L34e PF01199.13 KFX87064.1 - 0.21 11.8 1.0 0.43 10.8 0.7 1.5 1 1 0 1 1 1 0 Ribosomal protein L34e DUF1180 PF06679.7 KFX87064.1 - 2.7 7.8 4.8 0.58 10.0 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Glyco_hydro_3 PF00933.16 KFX87065.1 - 1e-84 284.0 0.0 1.5e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX87065.1 - 5.9e-67 225.4 0.0 1.5e-66 224.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX87065.1 - 3.6e-25 87.6 1.4 8.6e-25 86.4 0.9 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KFX87065.1 - 4.1e-13 49.2 0.0 8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Transketolase_N PF00456.16 KFX87066.1 - 3e-147 489.8 0.3 4e-147 489.3 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFX87066.1 - 2.8e-44 150.7 0.0 4.7e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFX87066.1 - 4.2e-13 49.3 0.0 8.2e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFX87066.1 - 0.00014 20.9 0.1 0.00038 19.4 0.1 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Ank_2 PF12796.2 KFX87067.1 - 5.8e-13 48.9 0.0 2e-05 24.8 0.0 5.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX87067.1 - 5.5e-10 39.1 2.3 0.00071 19.7 0.0 6.4 6 0 0 6 6 6 1 Ankyrin repeats (many copies) NACHT PF05729.7 KFX87067.1 - 7.9e-10 38.6 0.2 2.3e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.1 KFX87067.1 - 1.8e-08 34.6 3.3 0.23 12.0 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 KFX87067.1 - 2.6e-06 27.5 0.2 1.5e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 KFX87067.1 - 3.1e-06 26.8 2.7 0.0011 19.0 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat KAP_NTPase PF07693.9 KFX87067.1 - 2.8e-05 23.2 1.0 0.046 12.7 0.2 2.5 2 0 0 2 2 2 2 KAP family P-loop domain Ank PF00023.25 KFX87067.1 - 0.00012 21.6 3.4 0.0082 15.9 0.0 5.0 5 1 0 5 5 5 1 Ankyrin repeat AAA_22 PF13401.1 KFX87067.1 - 0.002 18.2 0.2 0.016 15.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain Biotin_lipoyl PF00364.17 KFX87069.1 - 4.1e-18 64.7 1.1 5.4e-18 64.4 0.8 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KFX87069.1 - 0.051 13.2 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Biotin-lipoyl like HlyD PF00529.15 KFX87069.1 - 0.098 11.9 0.1 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Sec7 PF01369.15 KFX87070.1 - 3.1e-65 219.4 0.4 1.5e-64 217.1 0.1 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KFX87070.1 - 4.3e-51 172.6 4.4 4.3e-51 172.6 3.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFX87070.1 - 5.9e-30 102.6 3.2 4.3e-29 99.8 0.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 KFX87071.1 - 1.7e-33 114.9 0.1 2.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KFX87071.1 - 9.5e-23 79.2 0.0 1.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KFX87071.1 - 1.2e-11 43.3 0.0 2.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 KFX87071.1 - 0.0055 16.7 0.1 0.009 16.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX87071.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3386 PF11866.3 KFX87071.1 - 0.02 14.1 0.0 1.1 8.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3386) ELFV_dehydrog PF00208.16 KFX87071.1 - 0.05 13.1 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3815 PF12821.2 KFX87073.1 - 3e-24 85.4 18.8 3.6e-23 81.9 4.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DUF1212 PF06738.7 KFX87073.1 - 6e-06 25.8 4.5 6e-06 25.8 3.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) Methyltransf_23 PF13489.1 KFX87074.1 - 1.3e-21 76.9 0.2 3e-21 75.8 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX87074.1 - 1.6e-09 38.1 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87074.1 - 3.7e-09 36.3 0.0 2.1e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX87074.1 - 1.8e-08 34.9 0.0 1.4e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX87074.1 - 3.4e-06 27.4 0.0 2.3e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX87074.1 - 0.00026 21.2 0.0 0.00061 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFX87074.1 - 0.0033 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFX87074.1 - 0.0064 16.5 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX87074.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KFX87074.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KFX87074.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFX87074.1 - 0.12 11.4 0.0 1.1 8.3 0.0 2.2 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.14 KFX87075.1 - 4.8e-21 75.1 0.7 2.7e-10 39.8 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KFX87075.1 - 2.9e-06 26.4 0.0 5e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX87075.1 - 2.5e-05 24.2 0.1 5.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX87075.1 - 0.0016 18.8 0.1 0.13 12.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX87075.1 - 0.0097 14.7 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 KFX87075.1 - 0.042 13.8 0.4 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 KFX87075.1 - 0.076 12.6 0.5 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2370 PF10176.4 KFX87077.1 - 9.6e-79 264.0 0.6 5.3e-78 261.5 0.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DNA_methylase PF00145.12 KFX87078.1 - 2.8e-31 108.8 0.0 7e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KFX87078.1 - 5.9e-07 29.2 0.0 0.038 13.7 0.0 2.6 2 0 0 2 2 2 2 BAH domain MFS_1 PF07690.11 KFX87079.1 - 1.2e-30 106.4 24.9 1.2e-30 106.4 17.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.3 KFX87079.1 - 0.53 8.8 3.6 1.2 7.7 2.5 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter Glyco_tranf_2_4 PF13704.1 KFX87080.1 - 1.1e-07 32.0 0.5 2.1e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 KFX87080.1 - 0.00025 20.4 0.3 0.00046 19.5 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Fungal_trans PF04082.13 KFX87082.1 - 0.0056 15.5 9.8 0.0079 15.0 1.2 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_32N PF00251.15 KFX87083.1 - 3.2e-86 289.4 1.6 3.9e-86 289.1 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KFX87083.1 - 3.1e-18 65.9 0.0 6.1e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.19 KFX87084.1 - 1e-124 416.6 25.5 1.2e-124 416.4 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87084.1 - 1e-21 77.0 28.7 1e-21 77.0 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 KFX87084.1 - 0.41 10.3 0.1 0.41 10.3 0.0 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3154) Sugar_tr PF00083.19 KFX87085.1 - 3e-68 230.4 13.4 3e-43 148.0 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFX87085.1 - 3.3e-14 52.3 33.7 1e-11 44.1 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TBP PF00352.16 KFX87086.1 - 9e-70 230.0 0.2 5.3e-35 118.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFX87086.1 - 0.00038 20.4 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Complex1_LYR_1 PF13232.1 KFX87087.1 - 8.3e-08 32.3 1.4 1e-07 32.0 0.8 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX87087.1 - 9.6e-07 28.5 0.8 2.1e-06 27.4 0.6 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF3533 PF12051.3 KFX87088.1 - 3.4e-63 213.6 23.3 1.2e-31 109.8 0.1 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3533) Ank_4 PF13637.1 KFX87088.1 - 4.5e-15 55.7 1.0 8.8e-10 38.8 0.5 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFX87088.1 - 2.4e-13 50.2 0.1 1.6e-05 25.1 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX87088.1 - 2.4e-12 46.6 0.6 0.00024 21.2 0.4 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) APH PF01636.18 KFX87088.1 - 1.1e-09 38.3 0.0 5.1e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank PF00023.25 KFX87088.1 - 7.2e-09 35.0 3.5 0.0019 17.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFX87088.1 - 1.4e-08 34.1 4.9 0.014 15.5 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 KFX87088.1 - 0.0028 17.2 0.3 0.018 14.6 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain Choline_kinase PF01633.15 KFX87088.1 - 0.0048 16.5 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase bZIP_1 PF00170.16 KFX87089.1 - 0.0014 18.5 12.1 0.0037 17.1 8.4 1.7 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 KFX87089.1 - 0.009 15.7 1.7 0.018 14.7 1.1 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 KFX87089.1 - 0.017 15.4 1.3 0.017 15.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) CCDC155 PF14662.1 KFX87089.1 - 0.26 10.8 5.1 0.38 10.3 3.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KFX87089.1 - 0.28 11.5 1.3 0.58 10.5 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 KFX87089.1 - 0.78 9.6 13.1 14 5.5 9.1 2.3 1 1 0 1 1 1 0 Basic region leucine zipper FlxA PF14282.1 KFX87089.1 - 1.2 9.1 4.1 0.52 10.2 0.6 2.1 1 1 1 2 2 2 0 FlxA-like protein bZIP_Maf PF03131.12 KFX87089.1 - 1.5 9.1 9.2 2.7 8.3 6.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Pro_isomerase PF00160.16 KFX87091.1 - 7.5e-35 120.4 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFX87091.1 - 1.7e-15 56.3 0.0 3.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX87091.1 - 1.1e-10 41.3 0.0 2.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX87091.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 KFX87092.1 - 1.4e-07 31.3 6.7 2.4e-07 30.5 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.14 KFX87094.1 - 6.4e-33 112.3 0.0 1e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.4 KFX87095.1 - 3.8e-23 81.8 0.0 8.2e-22 77.4 0.0 2.6 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFX87095.1 - 0.00021 21.0 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX87095.1 - 0.00051 19.2 0.0 0.00096 18.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFX87095.1 - 0.0053 16.1 0.1 0.021 14.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 KFX87095.1 - 0.007 15.9 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFX87095.1 - 0.011 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-MIZ PF02891.15 KFX87096.1 - 5.7e-11 41.7 0.3 1.1e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.1 KFX87096.1 - 0.00016 21.7 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.3 KFX87096.1 - 0.0093 15.4 0.3 0.035 13.6 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit LexA_DNA_bind PF01726.11 KFX87096.1 - 0.017 14.6 0.0 3.3 7.3 0.0 2.8 2 0 0 2 2 2 0 LexA DNA binding domain Pkinase PF00069.20 KFX87098.1 - 3.1e-46 157.6 0.0 1.8e-31 109.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87098.1 - 5.6e-24 84.6 0.0 1.1e-13 50.8 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 KFX87098.1 - 1.5e-07 30.6 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFX87098.1 - 0.0066 16.2 0.1 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 KFX87099.1 - 2.5e-26 92.0 0.0 3.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KFX87099.1 - 0.01 15.7 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Peroxin-3 PF04882.7 KFX87100.1 - 1.1e-147 492.3 0.0 1.2e-147 492.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 KFX87101.1 - 4e-47 159.9 0.7 7.4e-47 159.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1649) AA_kinase PF00696.23 KFX87101.1 - 3.9e-36 124.8 0.0 7.1e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KFX87101.1 - 2.3e-16 58.8 0.8 2.4e-08 33.2 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 KFX87101.1 - 1.1e-10 40.8 2.8 1.4e-08 34.1 0.2 2.6 2 0 0 2 2 2 2 ACT domain Xan_ur_permease PF00860.15 KFX87102.1 - 1e-15 57.1 21.3 5e-14 51.6 14.7 3.0 1 1 0 1 1 1 1 Permease family Kin17_mid PF10357.4 KFX87103.1 - 2.4e-50 169.3 0.8 2.4e-50 169.3 0.6 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KFX87103.1 - 1.7e-05 24.8 3.2 4.3e-05 23.5 2.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX87103.1 - 2.8e-05 24.1 2.4 2.8e-05 24.1 1.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Menin PF05053.8 KFX87103.1 - 0.0091 14.2 8.3 0.012 13.8 5.7 1.1 1 0 0 1 1 1 1 Menin zf-C2H2_2 PF12756.2 KFX87103.1 - 0.012 15.7 0.4 0.012 15.7 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 KFX87103.1 - 0.1 11.9 0.3 0.22 10.8 0.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Spt4 PF06093.8 KFX87104.1 - 2.3e-32 110.6 0.4 2.8e-32 110.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-DHHC PF01529.15 KFX87104.1 - 0.28 10.5 1.6 0.38 10.1 1.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Metallophos PF00149.23 KFX87105.1 - 7.5e-37 126.6 0.0 1.1e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KFX87105.1 - 3e-28 97.6 0.0 1e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 KFX87105.1 - 4e-23 80.8 4.7 2.8e-17 62.1 0.6 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFX87105.1 - 3.6e-15 54.8 1.6 0.00063 19.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX87105.1 - 2.6e-10 39.6 1.0 0.00013 21.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX87105.1 - 2.3e-09 36.4 6.6 0.0044 16.8 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX87105.1 - 4.7e-06 26.7 1.3 0.13 12.9 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX87105.1 - 7.5e-05 23.2 3.1 0.36 11.5 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX87105.1 - 0.0021 18.3 1.9 1.3 9.3 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX87105.1 - 0.012 15.4 0.0 1 9.2 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX87105.1 - 0.014 15.8 1.6 2.8 8.5 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX87105.1 - 0.095 12.5 0.6 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFX87105.1 - 0.18 11.7 1.3 1.8 8.5 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Es2 PF09751.4 KFX87107.1 - 4.7e-109 365.5 0.0 1.3e-108 364.0 0.0 1.8 1 0 0 1 1 1 1 Nuclear protein Es2 ABC1 PF03109.11 KFX87107.1 - 5.2e-33 113.5 0.0 1.2e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 ABC1 family DUF947 PF06102.7 KFX87108.1 - 1.3e-51 174.7 28.1 1.3e-51 174.7 19.5 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF947) NIF PF03031.13 KFX87109.1 - 1.6e-15 57.1 0.0 2.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.14 KFX87110.1 - 9e-42 141.1 0.1 1.8e-41 140.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KFX87110.1 - 4.9e-16 58.4 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX87110.1 - 5e-13 48.7 0.0 1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFX87110.1 - 7.8e-09 35.5 0.1 3.5e-08 33.5 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX87110.1 - 7.5e-07 29.5 0.0 1.8e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX87110.1 - 3.8e-06 27.0 0.0 8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX87110.1 - 0.076 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.14 KFX87111.1 - 5.3e-36 123.5 0.3 7.9e-36 122.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRF1 PF07741.8 KFX87112.1 - 0.35 11.1 1.3 5.8 7.2 0.2 2.7 2 1 0 3 3 3 0 Brf1-like TBP-binding domain EF-hand_1 PF00036.27 KFX87113.1 - 2.4e-26 88.9 10.1 8.2e-07 27.8 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFX87113.1 - 1.4e-24 85.9 2.3 6.3e-13 48.6 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFX87113.1 - 5.5e-21 72.5 4.1 3.8e-05 23.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFX87113.1 - 7.5e-20 69.3 11.1 1.9e-06 26.9 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFX87113.1 - 3.9e-15 55.1 12.3 1.4e-05 24.6 0.6 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFX87113.1 - 4.9e-07 29.7 0.0 0.0006 19.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFX87113.1 - 1.9e-06 27.5 7.5 0.0024 17.6 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EPL1 PF10513.4 KFX87114.1 - 2.2e-28 99.4 6.7 2.2e-28 99.4 4.6 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like Rubis-subs-bind PF09273.6 KFX87115.1 - 3.2e-18 65.8 0.3 7.2e-18 64.7 0.2 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KFX87115.1 - 1.1e-13 51.7 0.0 7.1e-13 49.1 0.0 2.2 2 1 0 2 2 2 1 SET domain DAO PF01266.19 KFX87117.1 - 6e-15 55.0 0.3 4.5e-14 52.1 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX87117.1 - 8.1e-05 22.9 0.2 0.00018 21.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX87117.1 - 0.00012 22.0 0.5 0.00043 20.2 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX87117.1 - 0.00036 20.4 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX87117.1 - 0.0011 17.9 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KFX87117.1 - 0.0034 16.3 0.1 0.0042 15.9 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KFX87117.1 - 0.0039 16.3 0.0 0.0062 15.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KFX87117.1 - 0.025 13.0 0.1 0.034 12.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 KFX87117.1 - 0.026 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KFX87117.1 - 0.031 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KFX87117.1 - 0.032 13.9 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KFX87117.1 - 0.1 11.6 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KFX87117.1 - 0.14 11.5 0.3 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KFX87117.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain Glyco_hydro_61 PF03443.9 KFX87118.1 - 1.8e-50 171.7 0.0 2.1e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Grp1_Fun34_YaaH PF01184.14 KFX87119.1 - 4.2e-88 294.1 20.1 5.2e-88 293.8 13.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Herpes_capsid PF06112.6 KFX87121.1 - 3.5 7.6 8.7 0.98 9.4 0.2 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ATP-synt_DE_N PF02823.11 KFX87122.1 - 9.6e-17 60.5 0.1 1.5e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HAD_2 PF13419.1 KFX87126.1 - 5e-33 114.7 0.1 6e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX87126.1 - 3.8e-06 27.4 0.0 2.5e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX87126.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Med21 PF11221.3 KFX87127.1 - 8.3e-44 149.0 2.7 9.7e-44 148.8 1.9 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.1 KFX87127.1 - 0.0095 15.1 5.6 0.41 9.7 3.1 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.8 KFX87127.1 - 0.024 14.3 4.4 0.024 14.3 3.0 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 KIP1 PF07765.7 KFX87127.1 - 0.04 13.7 0.7 0.29 11.0 0.2 2.0 2 0 0 2 2 2 0 KIP1-like protein Orbi_VP5 PF00901.12 KFX87127.1 - 0.083 11.0 2.2 0.097 10.8 1.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 APG6 PF04111.7 KFX87127.1 - 0.79 8.7 5.2 1.2 8.1 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spore_III_AB PF09548.5 KFX87127.1 - 0.81 9.4 4.1 1.2 8.8 2.5 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2034 PF10356.4 KFX87128.1 - 8.2e-32 109.8 0.0 1.3e-15 57.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KFX87128.1 - 1.8e-09 37.3 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF4365 PF14280.1 KFX87128.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4365) TMEM141 PF15110.1 KFX87128.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TMEM141 protein family ResIII PF04851.10 KFX87130.1 - 1.3e-22 80.4 0.0 2.9e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFX87130.1 - 2.1e-14 53.1 0.0 5.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX87130.1 - 2e-10 40.4 0.0 6.7e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KFX87130.1 - 0.009 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TatD_DNase PF01026.16 KFX87131.1 - 1.1e-31 109.9 0.0 1.9e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase RGP PF03214.8 KFX87131.1 - 0.054 12.2 0.0 1.6 7.3 0.0 2.1 1 1 0 2 2 2 0 Reversibly glycosylated polypeptide Cullin PF00888.17 KFX87132.1 - 2.4e-202 673.5 11.9 2.8e-202 673.3 8.2 1.0 1 0 0 1 1 1 1 Cullin family Aldo_ket_red PF00248.16 KFX87133.1 - 6.5e-62 208.9 0.0 7.3e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family rve_2 PF13333.1 KFX87133.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain He_PIG PF05345.7 KFX87134.1 - 8.8e-16 57.6 16.3 2.2e-05 24.3 2.0 4.9 4 0 0 4 4 4 4 Putative Ig domain Big_3_4 PF13754.1 KFX87134.1 - 0.1 12.9 7.2 19 5.6 0.0 4.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Methyltransf_16 PF10294.4 KFX87135.1 - 3.7e-46 156.7 0.0 5.4e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Dirigent PF03018.9 KFX87135.1 - 0.013 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Dirigent-like protein Methyltransf_18 PF12847.2 KFX87135.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KFX87136.1 - 9.6e-61 205.1 0.4 1.1e-60 204.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87136.1 - 4.1e-21 75.2 0.0 6.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX87136.1 - 2e-07 30.9 0.0 6.4e-05 22.8 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFX87136.1 - 0.0038 16.2 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KFX87136.1 - 0.0057 16.2 0.1 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFX87136.1 - 0.038 13.0 0.3 0.095 11.7 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF257 PF03192.8 KFX87136.1 - 0.07 12.4 0.8 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 YrbL-PhoP_reg PF10707.4 KFX87136.1 - 0.076 12.3 0.5 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CDP-OH_P_transf PF01066.16 KFX87137.1 - 1.9e-17 63.4 7.6 1.9e-17 63.4 5.3 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase peroxidase PF00141.18 KFX87140.1 - 4.1e-49 167.1 0.0 6.5e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.2 KFX87141.1 - 0.047 13.4 0.1 0.047 13.4 0.1 1.8 2 0 0 2 2 2 0 F-box-like GrpB PF04229.9 KFX87142.1 - 2.6e-45 154.1 0.1 3e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 GrpB protein DUF3499 PF12005.3 KFX87142.1 - 0.078 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Epimerase PF01370.16 KFX87143.1 - 5.1e-18 65.3 0.0 7.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX87143.1 - 2.1e-12 46.5 0.0 2e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFX87143.1 - 8.8e-12 44.2 0.0 1.7e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX87143.1 - 1.1e-08 35.2 0.1 1.8e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX87143.1 - 9e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX87143.1 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KFX87143.1 - 0.00017 20.9 0.1 0.013 14.7 0.1 2.3 2 1 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 KFX87143.1 - 0.0021 18.4 0.0 0.0098 16.3 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KFX87143.1 - 0.0044 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX87143.1 - 0.06 12.2 0.1 0.28 10.0 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain HSF_DNA-bind PF00447.12 KFX87144.1 - 2.6e-36 123.9 0.4 3.8e-36 123.4 0.3 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.2 KFX87146.1 - 9.3e-05 22.0 0.1 0.00018 21.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX87146.1 - 0.0027 17.3 0.1 0.0073 15.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain ArabFuran-catal PF09206.6 KFX87147.1 - 2.5e-160 532.7 21.6 3.6e-160 532.2 15.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KFX87147.1 - 1.8e-62 209.2 3.8 2.9e-62 208.5 2.6 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) MFS_1 PF07690.11 KFX87148.1 - 2.2e-17 62.8 25.5 2.2e-17 62.8 17.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Esterase_phd PF10503.4 KFX87148.1 - 7.1e-17 61.3 0.7 1.4e-16 60.4 0.5 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase AIG2 PF06094.7 KFX87148.1 - 9.5e-12 45.3 0.0 2.1e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 AIG2-like family Peptidase_S9 PF00326.16 KFX87148.1 - 6.4e-11 41.8 2.2 1e-10 41.2 0.8 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX87148.1 - 1.1e-06 28.4 0.3 4.2e-06 26.5 0.2 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX87148.1 - 0.00059 18.6 0.1 0.001 17.8 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family CBM_1 PF00734.13 KFX87148.1 - 0.0012 18.4 8.7 0.0012 18.4 6.1 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Sugar_tr PF00083.19 KFX87148.1 - 0.0013 17.4 8.0 0.0013 17.4 5.6 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 KFX87148.1 - 0.0037 17.1 1.9 0.0056 16.5 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF3129 PF11327.3 KFX87149.1 - 1.5e-63 213.9 13.8 1.5e-63 213.9 9.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) ABC_membrane PF00664.18 KFX87150.1 - 6.8e-69 232.3 28.8 1.5e-35 122.9 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX87150.1 - 8.4e-62 207.4 0.0 8.2e-32 110.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX87150.1 - 7.1e-12 45.0 2.3 7.7e-05 22.0 1.3 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX87150.1 - 2.9e-09 37.7 0.0 0.0034 18.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX87150.1 - 1.3e-08 35.0 2.6 0.0017 18.3 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KFX87150.1 - 1.4e-08 35.0 0.2 0.047 13.6 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFX87150.1 - 1.4e-07 30.8 0.2 0.0059 16.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX87150.1 - 7.9e-06 26.0 0.0 1.1 9.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KFX87150.1 - 2.5e-05 24.5 0.1 0.24 11.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 KFX87150.1 - 2.6e-05 24.1 0.0 0.34 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KFX87150.1 - 3.1e-05 23.9 1.7 0.0016 18.2 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF258 PF03193.11 KFX87150.1 - 3.4e-05 23.0 0.1 0.023 13.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX87150.1 - 0.00018 20.9 0.0 0.8 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFX87150.1 - 0.00032 20.5 0.6 1.7 8.6 0.1 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KFX87150.1 - 0.00041 20.7 0.0 0.45 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KFX87150.1 - 0.00058 19.3 0.7 0.15 11.5 0.1 2.7 3 0 0 3 3 2 1 AAA-like domain Zeta_toxin PF06414.7 KFX87150.1 - 0.0007 18.7 0.0 0.35 9.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KFX87150.1 - 0.00084 18.0 1.8 0.17 10.4 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA PF00004.24 KFX87150.1 - 0.0024 18.0 0.1 20 5.4 0.1 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KFX87150.1 - 0.0028 17.3 0.1 0.75 9.4 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KFX87150.1 - 0.0038 17.1 0.2 2.1 8.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KFX87150.1 - 0.005 16.4 0.1 1.5 8.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 KFX87150.1 - 0.0075 15.9 0.0 4 7.1 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KFX87150.1 - 0.021 13.6 0.1 6.1 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.1 KFX87150.1 - 0.033 12.7 0.1 0.83 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_5 PF07728.9 KFX87150.1 - 0.057 13.1 0.1 5.6 6.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX87150.1 - 0.23 11.3 0.0 35 4.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KFX87150.1 - 0.76 8.7 0.0 1.6 7.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pyr_redox_2 PF07992.9 KFX87151.1 - 1e-09 38.5 0.0 1.8e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX87151.1 - 2.2e-09 37.6 1.1 3.8e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX87151.1 - 1.2e-08 35.3 0.0 0.037 14.0 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX87151.1 - 0.015 14.1 0.3 0.17 10.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFX87151.1 - 0.1 11.4 2.5 10 4.8 0.0 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase Alpha-amylase PF00128.19 KFX87152.1 - 1.3e-62 212.0 0.0 1.7e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MFS_1 PF07690.11 KFX87152.1 - 7.2e-18 64.4 48.6 7.2e-18 64.4 33.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1966 PF09260.6 KFX87152.1 - 1.5e-16 60.2 1.1 7.3e-16 58.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) TRI12 PF06609.8 KFX87152.1 - 2.7e-09 35.8 23.8 5.1e-09 34.8 16.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1428 PF07237.6 KFX87152.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) DUF187 PF02638.10 KFX87152.1 - 0.13 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Pkinase PF00069.20 KFX87155.1 - 1.2e-07 31.1 0.0 2.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87155.1 - 6.8e-05 22.0 0.0 0.00018 20.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Zn_clus PF00172.13 KFX87156.1 - 4.3 7.3 12.2 8.5 6.3 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mtc PF03820.12 KFX87157.1 - 1.9e-37 128.6 0.0 2.1e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier FA_hydroxylase PF04116.8 KFX87159.1 - 5.1e-17 62.3 10.1 5.1e-17 62.3 7.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Transport_MerF PF11431.3 KFX87159.1 - 0.26 10.9 3.5 0.82 9.3 0.6 2.5 2 0 0 2 2 2 0 Membrane transport protein MerF TCTP PF00838.12 KFX87160.1 - 2.9e-65 219.2 3.5 3.3e-65 219.0 2.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein S4 PF01479.20 KFX87160.1 - 0.015 14.7 0.1 0.17 11.3 0.1 2.3 1 1 1 2 2 2 0 S4 domain Lactamase_B_2 PF12706.2 KFX87161.1 - 3.6e-34 118.0 0.1 8e-34 116.8 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KFX87161.1 - 8.7e-26 89.1 0.1 2.8e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KFX87161.1 - 6.3e-05 22.7 0.0 0.00023 20.9 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MIP PF00230.15 KFX87165.1 - 1.6e-49 168.4 4.1 2e-49 168.1 2.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein p450 PF00067.17 KFX87166.1 - 6.3e-15 54.6 0.1 6.8e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NUP PF06516.6 KFX87168.1 - 4.6e-121 403.4 0.0 5.6e-121 403.1 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Ank PF00023.25 KFX87169.1 - 6.9e-30 101.3 0.2 2e-08 33.6 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 KFX87169.1 - 1.5e-27 95.7 0.0 2.4e-16 59.8 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFX87169.1 - 1.5e-20 71.2 0.2 0.00018 21.4 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KFX87169.1 - 6.3e-19 67.5 0.2 5.5e-05 23.2 0.0 4.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX87169.1 - 6.3e-17 61.6 0.6 6.2e-07 29.7 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) NACHT PF05729.7 KFX87169.1 - 1.7e-06 27.8 0.1 5.7e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 NACHT domain VCBS PF13517.1 KFX87170.1 - 7.1e-26 90.3 39.1 4.1e-12 46.2 0.4 7.3 3 2 4 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 KFX87170.1 - 2e-22 80.2 0.8 1.1e-11 45.2 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.18 KFX87170.1 - 3.1e-20 71.2 21.4 0.003 17.2 0.4 7.0 6 0 0 6 6 6 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 KFX87170.1 - 8.9e-13 48.0 6.5 0.14 11.5 0.0 6.4 3 2 3 6 6 6 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.17 KFX87170.1 - 1.3e-08 34.9 9.2 2.3e-07 30.8 0.1 3.2 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFX87170.1 - 0.005 16.5 0.2 0.065 12.9 0.0 2.7 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Peptidase_MA_2 PF13485.1 KFX87170.1 - 0.0084 16.1 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 1 Peptidase MA superfamily Ebola_NP PF05505.7 KFX87172.1 - 1 7.3 8.4 1 7.3 5.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Pex14_N PF04695.8 KFX87172.1 - 3.1 7.8 9.6 5.6 7.0 6.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.2 KFX87172.1 - 6.4 4.3 7.4 6.4 4.3 5.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Noggin PF05806.7 KFX87176.1 - 0.18 11.0 2.2 0.22 10.7 1.6 1.1 1 0 0 1 1 1 0 Noggin Mannosyl_trans2 PF04188.8 KFX87178.1 - 8.1e-66 222.7 3.1 1e-65 222.3 2.2 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) CHCH PF06747.8 KFX87178.1 - 0.064 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 CHCH domain Fic PF02661.13 KFX87181.1 - 2.9e-20 72.7 0.0 1.2e-19 70.7 0.0 2.0 3 0 0 3 3 3 1 Fic/DOC family PH PF00169.24 KFX87182.1 - 2.3e-11 43.8 0.0 5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KFX87182.1 - 0.0088 13.6 0.5 0.014 12.9 0.4 1.2 1 0 0 1 1 1 1 Prominin tRNA-synt_2b PF00587.20 KFX87183.1 - 4.2e-46 156.6 0.4 7.1e-46 155.9 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX87183.1 - 7e-19 67.5 0.0 1.8e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KFX87183.1 - 6e-13 48.4 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KFX87183.1 - 8.6e-13 47.9 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Gar1 PF04410.9 KFX87184.1 - 2.7e-42 143.8 0.4 1.1e-41 141.8 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DUF2013 PF09431.5 KFX87185.1 - 8.7e-50 168.1 5.4 8.7e-50 168.1 3.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) RHH_4 PF13467.1 KFX87185.1 - 0.039 13.8 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix domain DnaJ PF00226.26 KFX87186.1 - 9.5e-22 76.5 1.3 9.5e-22 76.5 0.9 2.7 4 0 0 4 4 3 1 DnaJ domain TPR_11 PF13414.1 KFX87186.1 - 2.1e-18 65.7 0.3 1.4e-09 37.4 0.0 5.0 3 3 2 5 5 5 3 TPR repeat TPR_1 PF00515.23 KFX87186.1 - 1.2e-14 53.1 0.0 0.0021 17.5 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFX87186.1 - 7.2e-14 50.5 0.3 0.09 12.7 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX87186.1 - 3.1e-10 40.4 0.4 0.049 14.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX87186.1 - 9.1e-09 34.4 2.5 0.14 12.0 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX87186.1 - 3.6e-08 33.2 1.0 0.037 13.9 0.0 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX87186.1 - 4.5e-08 33.3 0.2 0.068 13.5 0.0 5.1 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX87186.1 - 6.4e-07 29.0 0.0 0.043 14.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX87186.1 - 8e-07 28.8 0.3 0.098 12.5 0.0 3.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX87186.1 - 9.1e-07 28.9 0.0 2.1 9.2 0.0 6.4 2 2 6 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX87186.1 - 2.2e-06 27.0 0.1 0.036 13.8 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX87186.1 - 2.6e-06 27.5 0.0 0.16 12.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Transcrip_act PF04949.8 KFX87186.1 - 0.033 13.8 1.9 0.52 9.9 0.1 2.6 2 0 0 2 2 2 0 Transcriptional activator CENP-F_leu_zip PF10473.4 KFX87187.1 - 0.15 11.9 3.0 2.6 7.9 0.6 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MerR-DNA-bind PF09278.6 KFX87187.1 - 1.4 9.3 0.0 1.4 9.3 0.0 3.9 4 0 0 4 4 4 0 MerR, DNA binding Vac14_Fig4_bd PF11916.3 KFX87188.1 - 1e-82 275.7 7.4 1e-82 275.7 5.1 2.2 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KFX87188.1 - 5.2e-47 158.2 0.0 7.7e-44 148.0 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KFX87188.1 - 2.4e-09 36.4 3.3 0.00039 20.2 0.0 6.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KFX87188.1 - 5.8e-09 36.1 6.3 0.0017 18.7 0.1 5.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 KFX87188.1 - 2.1e-08 34.3 3.8 0.0032 17.7 0.0 5.2 5 0 0 5 5 5 1 HEAT repeats CLASP_N PF12348.3 KFX87188.1 - 0.0054 16.1 0.1 0.9 8.8 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 KFX87188.1 - 0.0096 15.7 0.1 12 5.8 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.19 KFX87189.1 - 1.3e-34 119.8 26.2 1.9e-34 119.3 18.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFX87189.1 - 3.7e-10 39.4 0.0 7.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S14 PF00253.16 KFX87190.1 - 1.1 8.6 5.5 0.79 9.1 1.8 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Pyr_redox_dim PF02852.17 KFX87191.1 - 2.4e-40 136.9 1.0 4.9e-40 135.9 0.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFX87191.1 - 8.9e-37 126.9 22.1 1e-35 123.4 15.3 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX87191.1 - 1e-22 80.3 13.4 1.3e-19 70.3 0.9 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX87191.1 - 3.4e-10 39.5 0.3 3.4e-10 39.5 0.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KFX87191.1 - 8.3e-10 38.0 8.6 6.3e-09 35.1 1.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFX87191.1 - 1e-09 38.2 5.0 5e-06 26.4 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX87191.1 - 3.6e-08 32.6 11.9 8.9e-08 31.3 3.0 2.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 KFX87191.1 - 3.1e-07 29.7 3.9 1.4e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFX87191.1 - 5.4e-07 28.8 19.6 7.3e-06 25.1 0.5 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFX87191.1 - 9.8e-07 28.1 6.3 0.0064 15.5 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KFX87191.1 - 2.9e-05 22.7 17.2 4.9e-05 21.9 1.6 4.0 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFX87191.1 - 3.6e-05 23.9 5.6 0.011 15.8 1.8 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX87191.1 - 8.5e-05 21.6 0.7 0.46 9.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KFX87191.1 - 0.00034 20.2 3.4 0.15 11.6 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KFX87191.1 - 0.0018 18.4 1.8 0.5 10.6 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KFX87191.1 - 0.093 11.7 1.0 1.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.14 KFX87191.1 - 0.18 9.9 0.7 0.29 9.2 0.5 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 KFX87191.1 - 0.34 9.7 7.3 0.042 12.7 0.7 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KFX87191.1 - 0.89 9.1 8.6 0.85 9.2 0.5 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KFX87191.1 - 3.1 6.3 9.7 0.024 13.2 0.8 1.7 2 0 0 2 2 2 0 Tryptophan halogenase SRP14 PF02290.10 KFX87192.1 - 3.4e-26 90.9 0.8 3.9e-26 90.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.3 KFX87192.1 - 0.095 12.5 0.0 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 MIF4G PF02854.14 KFX87193.1 - 1.9e-20 73.1 0.4 3.6e-20 72.2 0.3 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KFX87193.1 - 1.7e-19 69.5 0.1 4.3e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 MA3 domain RRM_1 PF00076.17 KFX87194.1 - 2.8e-53 177.4 0.0 4.1e-18 64.7 0.0 3.8 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX87194.1 - 1.6e-42 143.3 0.0 6.1e-14 51.7 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX87194.1 - 1.1e-23 82.7 0.0 2.6e-06 27.1 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX87194.1 - 7.4e-06 25.7 0.0 0.79 9.6 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KFX87194.1 - 8.8e-06 25.3 0.0 0.41 10.4 0.0 4.0 4 1 0 4 4 4 2 Limkain b1 ATP-grasp_2 PF08442.5 KFX87194.1 - 0.00036 19.9 0.0 0.023 14.0 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain Arv1 PF04161.8 KFX87196.1 - 4.3e-48 163.9 0.0 5.3e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.8 KFX87197.1 - 1.7e-26 92.0 2.8 1.9e-26 91.8 1.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H OppC_N PF12911.2 KFX87197.1 - 0.015 14.6 0.8 0.54 9.6 0.1 2.1 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1129 PF06570.6 KFX87197.1 - 0.035 13.3 0.5 0.044 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Claudin_2 PF13903.1 KFX87197.1 - 0.046 13.4 1.7 0.051 13.2 1.2 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction YfhO PF09586.5 KFX87197.1 - 0.091 10.7 0.6 0.094 10.7 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABC2_membrane_2 PF12679.2 KFX87197.1 - 0.12 11.1 3.2 0.14 10.9 2.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Pox_A14 PF05767.7 KFX87197.1 - 0.17 11.8 0.9 0.22 11.5 0.6 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4131 PF13567.1 KFX87197.1 - 0.36 10.2 2.7 0.37 10.1 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MutL_C PF08676.6 KFX87198.1 - 3.5e-23 81.8 0.0 7.6e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFX87198.1 - 7.5e-19 67.3 0.0 2.2e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFX87198.1 - 5.6e-15 55.2 0.6 9.3e-14 51.2 0.1 3.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFX87198.1 - 4.5e-12 45.6 2.0 4.8e-12 45.5 0.0 2.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PEGSRP PF07623.6 KFX87199.1 - 0.018 14.3 0.6 0.045 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Pyr_redox_2 PF07992.9 KFX87200.1 - 1.9e-05 24.6 0.0 0.00013 21.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX87200.1 - 0.00063 19.8 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ETF PF01012.16 KFX87201.1 - 8.6e-41 139.3 2.5 8.7e-41 139.3 0.6 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KFX87201.1 - 7.9e-35 118.3 0.3 1.8e-34 117.1 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 KFX87202.1 - 1.3e-34 118.1 0.1 2.8e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KFX87202.1 - 1.8e-06 27.8 0.1 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX87202.1 - 6e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRM_6 PF14259.1 KFX87203.1 - 4.5e-10 39.3 1.3 1.4e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX87203.1 - 8.3e-08 31.9 0.2 2e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KFX87203.1 - 2.4e-07 30.7 0.0 4.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 KFX87203.1 - 0.00021 20.8 5.6 0.0004 19.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 KFX87203.1 - 0.00029 20.4 4.2 0.00038 20.0 0.1 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX87203.1 - 0.0067 16.1 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif U79_P34 PF03064.11 KFX87203.1 - 1.3 8.4 7.9 3.2 7.2 5.5 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RRM_3 PF08777.6 KFX87203.1 - 2 8.2 7.9 0.28 11.0 0.1 2.9 3 0 0 3 3 3 0 RNA binding motif Myb_DNA-binding PF00249.26 KFX87204.1 - 0.021 14.8 0.0 0.065 13.3 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain GTP_EFTU PF00009.22 KFX87205.1 - 3.3e-61 206.0 0.2 4.5e-61 205.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFX87205.1 - 3.1e-36 123.5 0.0 1.4e-35 121.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KFX87205.1 - 1.8e-21 75.8 0.0 1e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX87205.1 - 8.2e-13 48.2 0.9 1.5e-11 44.2 0.0 3.3 4 0 0 4 4 4 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFX87205.1 - 1.3e-11 44.1 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KFX87205.1 - 1.7e-05 24.7 0.1 3.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 KFX87207.1 - 1.3e-104 349.3 3.4 1.6e-104 349.0 2.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha E1-E2_ATPase PF00122.15 KFX87211.1 - 9.3e-21 73.9 0.1 1.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFX87211.1 - 2.8e-20 73.2 0.1 7.2e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX87211.1 - 1e-14 55.4 0.1 1e-13 52.2 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX87211.1 - 1.1e-11 44.5 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX87211.1 - 0.00062 19.4 0.1 0.008 15.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFX87211.1 - 0.02 15.1 0.1 0.06 13.5 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PHF5 PF03660.9 KFX87212.1 - 1.3e-33 115.2 6.0 1.9e-33 114.6 4.1 1.3 1 0 0 1 1 1 1 PHF5-like protein OmpH PF03938.9 KFX87213.1 - 0.0085 16.0 0.8 0.013 15.4 0.6 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) SPX PF03105.14 KFX87213.1 - 0.046 13.5 1.2 0.1 12.3 0.8 1.5 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.8 KFX87213.1 - 0.63 9.2 11.9 0.052 12.7 5.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pex26 PF07163.7 KFX87213.1 - 2.1 7.1 6.9 0.6 8.9 1.0 2.2 2 0 0 2 2 2 0 Pex26 protein APG6 PF04111.7 KFX87213.1 - 8 5.4 7.4 12 4.8 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF1 PF04857.15 KFX87214.1 - 5.1e-48 163.6 0.4 6.3e-48 163.3 0.3 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 KFX87214.1 - 0.00024 20.6 0.1 0.00066 19.2 0.1 1.7 2 0 0 2 2 2 1 3'-5' exonuclease Acetyltransf_3 PF13302.1 KFX87215.1 - 2e-34 118.7 0.0 2.6e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX87215.1 - 5.8e-06 26.3 0.0 1.6e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.7 KFX87215.1 - 0.0018 16.7 0.0 0.0034 15.8 0.0 1.4 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Acetyltransf_8 PF13523.1 KFX87215.1 - 0.0029 17.4 0.0 0.058 13.2 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX87215.1 - 0.031 14.3 0.1 0.098 12.6 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX87215.1 - 0.064 13.4 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 KFX87216.1 - 1.9e-07 30.6 17.6 3.9e-06 26.5 0.4 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ PF01011.16 KFX87216.1 - 0.0009 18.6 1.6 0.61 9.7 0.2 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat Methyltransf_31 PF13847.1 KFX87217.1 - 3.7e-06 26.5 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX87217.1 - 6.1e-06 26.6 0.1 1.9e-05 25.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX87217.1 - 3.1e-05 23.7 0.0 4.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX87217.1 - 0.015 15.7 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fe_hyd_lg_C PF02906.9 KFX87217.1 - 0.035 13.3 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Methyltransf_18 PF12847.2 KFX87217.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CAF-1_p150 PF11600.3 KFX87218.1 - 0.21 10.9 2.6 0.38 10.0 1.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SPX PF03105.14 KFX87220.1 - 0.7 9.6 5.9 1.4 8.6 4.1 1.8 1 1 0 1 1 1 0 SPX domain GCV_T PF01571.16 KFX87221.1 - 3.1e-13 49.6 0.0 2.5e-12 46.6 0.0 2.2 3 0 0 3 3 3 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFX87221.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 KFX87222.1 - 5.7e-36 122.2 0.8 1.1e-35 121.3 0.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KFX87222.1 - 1.8e-16 59.9 0.0 3.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 KFX87223.1 - 1.1e-34 118.5 0.2 1.5e-34 118.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.16 KFX87224.1 - 5.7e-120 399.5 3.5 6.9e-120 399.2 2.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 KFX87225.1 - 4.5e-26 90.3 0.3 5.7e-26 90.0 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) CRISPR_Cse1 PF09481.5 KFX87225.1 - 0.078 11.7 0.1 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF1308 PF07000.6 KFX87226.1 - 1.9e-73 247.1 0.1 3.1e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Lung_7-TM_R PF06814.8 KFX87228.1 - 3.2e-73 246.2 15.7 3.8e-73 246.0 10.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KFX87228.1 - 4.8 7.3 20.0 3.6 7.7 0.1 4.1 3 1 1 4 4 4 0 PrgI family protein DUF2392 PF10288.4 KFX87229.1 - 1.2e-28 99.5 0.0 2.1e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 KFX87229.1 - 0.014 14.8 0.0 0.063 12.7 0.0 2.0 2 0 0 2 2 2 0 PP-loop family Vfa1 PF08432.5 KFX87231.1 - 9.6e-56 188.6 18.4 1.3e-55 188.2 12.7 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 YABBY PF04690.8 KFX87231.1 - 0.018 15.3 2.2 0.021 15.0 1.6 1.1 1 0 0 1 1 1 0 YABBY protein SIC PF03482.8 KFX87231.1 - 0.02 14.5 1.5 0.032 13.8 1.0 1.5 1 1 0 1 1 1 0 sic protein MTBP_N PF14918.1 KFX87231.1 - 0.028 13.8 2.8 0.019 14.3 1.0 1.4 1 1 0 1 1 1 0 MDM2-binding SET PF00856.23 KFX87231.1 - 0.096 12.9 1.6 0.11 12.8 1.1 1.3 1 0 0 1 1 1 0 SET domain GAGA_bind PF06217.7 KFX87231.1 - 0.11 12.4 8.8 0.1 12.5 6.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 KFX87231.1 - 0.12 10.3 14.5 0.14 10.1 10.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 KFX87231.1 - 0.19 9.9 5.4 0.24 9.6 3.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Raftlin PF15250.1 KFX87231.1 - 0.21 10.0 6.7 0.25 9.8 4.7 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 KFX87231.1 - 0.27 9.7 8.2 0.31 9.5 5.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Borrelia_P83 PF05262.6 KFX87231.1 - 0.31 9.2 21.6 0.37 9.0 15.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1510 PF07423.6 KFX87231.1 - 0.4 10.0 22.6 0.52 9.6 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KFX87231.1 - 0.42 10.3 6.5 0.52 10.0 4.5 1.2 1 0 0 1 1 1 0 DDHD domain BTV_NS2 PF04514.7 KFX87231.1 - 0.48 9.2 13.8 0.54 9.0 9.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 KFX87231.1 - 0.51 9.1 12.3 0.69 8.6 8.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 KFX87231.1 - 0.62 9.8 15.3 1 9.1 10.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ycf1 PF05758.7 KFX87231.1 - 0.64 7.6 13.9 0.71 7.5 9.6 1.0 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 KFX87231.1 - 0.67 8.9 3.2 0.78 8.6 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 KFX87231.1 - 0.67 9.4 21.7 0.87 9.0 15.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sec62 PF03839.11 KFX87231.1 - 0.94 8.8 15.3 1.4 8.3 10.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.7 KFX87231.1 - 1.3 8.8 18.0 1.7 8.4 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CMV_1a PF12467.3 KFX87231.1 - 2.9 8.2 14.3 4.3 7.6 9.9 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family ATP11 PF06644.6 KFX87231.1 - 3.2 7.1 15.7 4.1 6.8 10.9 1.1 1 0 0 1 1 1 0 ATP11 protein Selenoprotein_S PF06936.6 KFX87231.1 - 3.3 7.1 13.8 4.3 6.8 9.5 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Pox_Ag35 PF03286.9 KFX87231.1 - 4.1 6.8 19.9 6.1 6.3 13.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TP53IP5 PF15331.1 KFX87231.1 - 4.4 7.1 11.7 5.5 6.8 8.1 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4246 PF14033.1 KFX87231.1 - 4.4 5.7 11.6 5.7 5.4 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Atrophin-1 PF03154.10 KFX87231.1 - 4.5 5.2 18.3 5.4 5.0 12.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Rhabdo_ncap PF00945.13 KFX87231.1 - 6.2 5.2 8.1 7.6 4.9 5.6 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FAM176 PF14851.1 KFX87231.1 - 6.7 6.3 10.8 10 5.8 7.5 1.4 1 0 0 1 1 1 0 FAM176 family UPF0560 PF10577.4 KFX87231.1 - 9.2 4.3 9.9 10 4.2 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.11 KFX87231.1 - 9.3 6.0 7.2 12 5.7 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.1 KFX87231.1 - 9.4 4.6 17.2 12 4.2 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rtt106 PF08512.7 KFX87232.1 - 3.4e-25 87.8 0.0 7.9e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CENP-T PF15511.1 KFX87232.1 - 3.5 6.7 14.3 5.5 6.1 9.9 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GHMP_kinases_C PF08544.8 KFX87233.1 - 4.8e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Trp_syntA PF00290.15 KFX87236.1 - 2.1e-91 305.0 0.3 3.4e-91 304.3 0.0 1.4 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 KFX87236.1 - 1.6e-46 158.9 1.1 2.4e-46 158.3 0.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 KFX87236.1 - 0.063 12.5 0.2 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 PcrB family AAA PF00004.24 KFX87237.1 - 2e-15 57.1 0.0 3.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFX87237.1 - 0.00078 20.2 0.7 0.13 13.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 KFX87237.1 - 0.00089 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX87237.1 - 0.0018 18.4 0.1 0.019 15.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX87237.1 - 0.0048 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 KFX87237.1 - 0.02 14.3 0.0 1.3 8.4 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_5 PF07728.9 KFX87237.1 - 0.048 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KFX87237.1 - 0.048 13.9 0.0 14 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFX87237.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KFX87237.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KFX87238.1 - 7.9e-60 202.1 0.0 9.5e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87238.1 - 3.9e-30 104.7 0.0 5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX87238.1 - 0.00041 19.4 0.0 0.00091 18.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFX87238.1 - 0.0072 16.0 0.1 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX87238.1 - 0.014 14.4 0.2 0.028 13.4 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1640 PF07798.6 KFX87239.1 - 1.9e-10 41.0 6.0 1.9e-10 41.0 4.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) CAS_CSE1 PF03378.10 KFX87240.1 - 4.1e-155 516.3 0.0 3e-154 513.5 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KFX87240.1 - 2.3e-153 510.1 0.6 3.5e-153 509.5 0.4 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KFX87240.1 - 6.7e-12 45.1 0.0 2.3e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFX87240.1 - 0.013 15.4 9.6 0.41 10.5 0.0 5.8 7 0 0 7 7 7 0 Exportin 1-like protein DUF3384 PF11864.3 KFX87241.1 - 2.9e-91 306.2 0.0 4.7e-91 305.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KFX87241.1 - 2e-55 187.0 0.0 3.4e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KFX87241.1 - 2.1e-35 122.4 1.0 5.8e-32 111.1 0.0 2.4 2 0 0 2 2 2 2 Tuberin DER1 PF04511.10 KFX87242.1 - 4e-26 91.7 3.3 4.7e-26 91.5 2.3 1.0 1 0 0 1 1 1 1 Der1-like family DUF1770 PF08589.5 KFX87243.1 - 2e-25 89.2 1.3 3.1e-25 88.6 0.9 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) ABC_tran PF00005.22 KFX87244.1 - 9.1e-17 61.6 0.0 2.7e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFX87244.1 - 1.2e-09 38.5 0.4 0.0013 18.8 0.1 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 KFX87244.1 - 1.5e-05 24.2 0.0 0.096 11.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KFX87244.1 - 0.00011 21.5 0.0 0.4 9.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX87244.1 - 0.00023 20.5 0.4 0.00053 19.4 0.1 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KFX87244.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KFX87244.1 - 0.0034 17.7 0.1 0.0066 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX87244.1 - 0.0052 16.7 0.2 0.0071 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF3584 PF12128.3 KFX87244.1 - 0.0064 13.9 0.3 0.0083 13.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 KFX87244.1 - 0.0065 15.9 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KFX87244.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KFX87244.1 - 0.018 15.8 0.9 0.037 14.8 0.6 1.7 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KFX87244.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 KFX87244.1 - 0.077 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 KFX87244.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KFX87244.1 - 0.099 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 KFX87244.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFX87244.1 - 0.12 12.1 0.8 0.69 9.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX87244.1 - 0.14 12.3 0.9 0.49 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFX87244.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 WD40 PF00400.27 KFX87245.1 - 7.5e-57 187.3 17.3 7.3e-10 38.3 0.0 12.4 13 0 0 13 13 13 8 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFX87245.1 - 0.0063 15.3 0.2 0.11 11.2 0.0 2.6 2 1 1 3 3 3 1 Nup133 N terminal like WHIM1 PF15612.1 KFX87246.1 - 0.00073 19.3 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 KFX87246.1 - 0.15 9.9 9.2 0.21 9.4 6.4 1.3 1 0 0 1 1 1 0 Nop14-like family MSP1_C PF07462.6 KFX87246.1 - 3.7 5.8 6.3 6.9 4.9 4.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L2_C PF03947.13 KFX87247.1 - 4.1e-37 126.8 3.6 6.7e-37 126.1 2.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFX87247.1 - 4.2e-14 52.2 0.1 8.3e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 KFX87248.1 - 8.4e-67 225.4 0.1 9.7e-67 225.2 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFX87248.1 - 0.034 13.3 0.0 0.084 12.0 0.0 1.6 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 KFX87249.1 - 1.9e-52 178.2 0.0 4.2e-52 177.0 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KFX87249.1 - 1.6e-19 70.1 0.7 4.8e-19 68.6 0.5 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_12 PF13424.1 KFX87249.1 - 0.00029 20.7 1.8 0.0008 19.2 1.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX87249.1 - 0.00046 19.7 0.7 0.0015 18.1 0.5 1.9 1 0 0 1 1 1 1 TPR repeat DUF4298 PF14131.1 KFX87249.1 - 0.086 12.7 3.2 1.9 8.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) zf-C2H2 PF00096.21 KFX87250.1 - 3.8 8.0 14.5 0.65 10.4 0.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type TB2_DP1_HVA22 PF03134.14 KFX87251.1 - 4.1e-32 109.7 4.9 6.1e-32 109.2 3.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Kei1 PF08552.6 KFX87251.1 - 0.049 13.2 4.9 0.91 9.1 1.5 2.2 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Bestrophin PF01062.16 KFX87251.1 - 1.5 7.7 6.6 3.2 6.6 4.6 1.6 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF2207 PF09972.4 KFX87251.1 - 3.3 6.1 9.6 6.5 5.2 6.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RFX_DNA_binding PF02257.10 KFX87252.1 - 4.9e-30 103.5 0.1 1.5e-29 101.9 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Beta-lactamase PF00144.19 KFX87254.1 - 1.3e-46 159.1 0.3 2.3e-46 158.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KFX87254.1 - 4.4e-17 61.7 0.0 8.1e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Pec_lyase_C PF00544.14 KFX87255.1 - 1.4e-43 148.7 0.3 2.2e-43 148.0 0.2 1.3 1 0 0 1 1 1 1 Pectate lyase DUF2414 PF10309.4 KFX87256.1 - 3.6e-22 77.8 0.0 6.2e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFX87256.1 - 0.084 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain Aspzincin_M35 PF14521.1 KFX87257.1 - 0.0002 21.8 0.0 0.0004 20.9 0.0 1.7 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Ank_2 PF12796.2 KFX87259.1 - 4e-11 43.1 0.0 0.00019 21.6 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX87259.1 - 3.8e-10 39.0 0.0 0.45 10.4 0.0 5.7 4 2 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KFX87259.1 - 5.3e-09 36.3 0.0 0.11 12.9 0.0 5.2 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX87259.1 - 4.1e-07 29.6 0.7 1 9.8 0.0 5.7 6 1 1 7 7 7 3 Ankyrin repeat Ank_2 PF12796.2 KFX87260.1 - 8.5e-31 106.1 0.0 1.2e-10 41.5 0.0 3.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX87260.1 - 1.3e-17 63.7 0.4 0.0052 17.2 0.0 5.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KFX87260.1 - 1.3e-16 59.4 0.5 0.22 11.3 0.1 6.4 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 KFX87260.1 - 2.2e-15 55.2 1.7 0.014 15.5 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KFX87260.1 - 1e-08 35.1 3.3 0.0055 16.9 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 KFX87260.1 - 0.01 15.8 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Epimerase PF01370.16 KFX87261.1 - 6.4e-12 45.4 0.1 1e-11 44.7 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX87261.1 - 3.5e-09 35.7 0.0 5.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KFX87261.1 - 1.8e-06 27.4 0.3 2.8e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX87261.1 - 5.6e-06 26.4 1.7 1.3e-05 25.3 1.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX87261.1 - 1.1e-05 24.5 0.1 6.4e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFX87261.1 - 0.00061 19.7 2.9 0.0015 18.5 2.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX87261.1 - 0.016 14.1 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 KFX87261.1 - 0.021 14.4 3.3 0.065 12.9 2.3 1.8 1 1 0 1 1 1 0 KR domain Ank_2 PF12796.2 KFX87262.1 - 7.4e-50 167.2 0.0 8.2e-11 42.1 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX87262.1 - 7.4e-30 101.2 11.9 5.6e-05 22.7 0.2 9.7 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KFX87262.1 - 6.6e-18 64.7 5.3 0.0066 16.9 0.6 7.1 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX87262.1 - 3e-17 60.9 8.6 0.014 15.5 0.1 9.4 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 KFX87262.1 - 7.4e-17 61.0 9.0 3.7e-05 23.8 0.2 7.0 6 2 2 8 8 8 4 Ankyrin repeats (many copies) F-box-like PF12937.2 KFX87262.1 - 0.0035 17.0 0.5 0.016 14.9 0.2 2.0 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 KFX87263.1 - 3e-37 128.1 25.4 3.6e-37 127.9 17.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFX87263.1 - 0.00049 19.6 4.5 0.0017 17.8 3.1 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 KFX87264.1 - 3.5e-24 85.0 0.1 6.7e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87264.1 - 5.4e-06 26.2 6.2 9.3e-06 25.4 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.7 KFX87265.1 - 1.1e-56 190.4 0.0 1.5e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.9 KFX87266.1 - 6.4e-195 648.3 0.0 9.6e-195 647.7 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFX87266.1 - 8.9e-95 317.1 0.3 1.9e-94 316.0 0.1 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFX87266.1 - 7.9e-54 181.8 2.0 9.8e-53 178.2 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region CoA_binding_2 PF13380.1 KFX87267.1 - 2.2e-28 98.7 0.0 2.8e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 KFX87267.1 - 0.037 14.5 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain HET PF06985.6 KFX87268.1 - 1.1e-20 74.1 4.6 4.1e-17 62.6 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 KFX87269.1 - 5e-05 23.1 8.8 0.00016 21.5 6.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.15 KFX87270.1 - 2.1e-33 115.4 0.0 2.6e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 KFX87270.1 - 8.9e-05 22.5 0.0 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Big_4 PF07532.6 KFX87270.1 - 0.045 13.2 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) DUF2976 PF11190.3 KFX87271.1 - 0.054 13.0 0.4 0.054 13.0 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) COesterase PF00135.23 KFX87272.1 - 3.3e-89 300.0 0.8 5.4e-89 299.3 0.6 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX87272.1 - 2.2e-06 27.4 0.1 1.1e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KFX87272.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme 5-FTHF_cyc-lig PF01812.15 KFX87273.1 - 6.6e-30 104.2 0.0 8.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ETC_C1_NDUFA5 PF04716.9 KFX87274.1 - 1.6e-23 82.0 1.1 4.1e-23 80.6 0.2 2.1 2 0 0 2 2 2 1 ETC complex I subunit conserved region Thioredoxin PF00085.15 KFX87275.1 - 7.4e-39 131.6 0.3 3e-24 84.6 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFX87275.1 - 1.5e-14 54.1 0.0 1.6e-07 31.3 0.0 4.4 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFX87275.1 - 1.5e-07 31.4 0.5 0.017 15.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFX87275.1 - 5.4e-06 26.5 6.4 0.023 14.8 0.0 4.5 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KFX87275.1 - 7.4e-06 25.6 0.0 0.085 12.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_7 PF13899.1 KFX87275.1 - 0.00027 20.8 0.3 0.0051 16.8 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KFX87275.1 - 0.011 15.5 0.0 7.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KFX87275.1 - 0.011 15.1 0.1 2.5 7.5 0.0 3.0 3 1 1 4 4 4 0 F plasmid transfer operon protein Tyr-DNA_phospho PF06087.7 KFX87276.1 - 1.6e-126 422.5 0.0 1.9e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFX87276.1 - 0.0061 16.2 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.17 KFX87276.1 - 0.14 11.9 0.1 5.2 7.0 0.3 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif ACBP PF00887.14 KFX87277.1 - 1.9e-22 78.7 0.7 2.2e-22 78.5 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Piwi PF02171.12 KFX87278.1 - 1.2e-63 214.9 0.0 1.8e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFX87278.1 - 9.3e-10 37.9 0.0 1.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFX87278.1 - 2.7e-08 33.0 0.0 7.1e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Amidohydro_1 PF01979.15 KFX87281.1 - 1.1e-60 206.0 2.3 1.8e-60 205.3 1.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KFX87281.1 - 3.1e-54 182.2 2.1 7.5e-54 181.0 1.4 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KFX87281.1 - 3.7e-41 139.0 1.1 5.5e-41 138.4 0.2 1.7 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KFX87281.1 - 2.8e-38 129.9 0.1 5.7e-38 128.9 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit MFS_1 PF07690.11 KFX87281.1 - 4.2e-24 84.9 28.8 4.2e-24 84.9 20.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_5 PF13594.1 KFX87281.1 - 1.6e-05 24.6 3.2 4.7e-05 23.1 2.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFX87281.1 - 1.9e-05 24.1 0.0 0.004 16.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family MFS_2 PF13347.1 KFX87281.1 - 5.5e-05 21.7 1.6 5.5e-05 21.7 1.1 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein TraE PF05309.6 KFX87281.1 - 0.061 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 TraE protein Sugar_tr PF00083.19 KFX87281.1 - 0.66 8.4 11.2 0.09 11.3 4.6 1.7 2 0 0 2 2 2 0 Sugar (and other) transporter zf-RING_2 PF13639.1 KFX87282.1 - 5.3e-14 51.7 6.5 9.5e-14 50.9 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX87282.1 - 5.9e-08 32.6 6.4 5.9e-08 32.6 4.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX87282.1 - 1.3e-06 27.9 5.4 1.3e-06 27.9 3.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX87282.1 - 4.1e-06 26.8 2.9 1.1e-05 25.4 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFX87282.1 - 6.2e-06 25.8 4.5 1.2e-05 24.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX87282.1 - 1.7e-05 24.4 3.8 3.6e-05 23.3 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX87282.1 - 0.0014 18.4 4.0 0.0037 17.0 2.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFX87282.1 - 0.0027 17.3 5.2 0.0027 17.3 3.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX87282.1 - 0.0036 17.1 5.3 0.0095 15.7 3.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFX87282.1 - 0.078 12.5 2.9 0.16 11.5 2.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KFX87282.1 - 0.12 12.4 2.3 0.21 11.6 1.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 KFX87282.1 - 0.13 11.7 6.8 0.59 9.6 3.9 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KFX87282.1 - 0.22 11.2 3.4 0.39 10.4 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 KFX87282.1 - 8.3 6.4 7.6 0.46 10.5 1.1 1.9 2 0 0 2 2 2 0 RING-like domain Ada3 PF10198.4 KFX87283.1 - 4.9e-38 129.8 0.5 4.9e-38 129.8 0.3 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Maf PF02545.9 KFX87284.1 - 1.4e-34 118.9 0.0 1.6e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein EF-1_beta_acid PF10587.4 KFX87284.1 - 0.084 13.0 3.7 0.18 11.9 2.6 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region NPR2 PF06218.6 KFX87285.1 - 1.4e-122 409.5 0.1 1.3e-107 360.2 0.1 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 KFX87285.1 - 0.017 13.6 0.0 0.039 12.4 0.0 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SnoaL_4 PF13577.1 KFX87287.1 - 2.3e-12 46.9 0.0 2.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KFX87287.1 - 0.035 14.1 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 KFX87288.1 - 7e-18 64.4 45.3 7e-18 64.4 31.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.16 KFX87289.1 - 0.015 14.2 0.0 0.017 14.0 0.0 1.0 1 0 0 1 1 1 0 Amidase DUF3322 PF11795.3 KFX87289.1 - 0.1 12.2 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) tRNA_int_endo_N PF02778.9 KFX87289.1 - 0.14 11.7 0.1 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain TMEM52 PF14979.1 KFX87290.1 - 2 8.2 4.1 3.5 7.5 0.3 2.3 1 1 1 2 2 2 0 Transmembrane 52 Beta_elim_lyase PF01212.16 KFX87291.1 - 1.2e-50 172.2 0.0 1.8e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Methyltransf_23 PF13489.1 KFX87291.1 - 9.2e-06 25.4 0.0 0.00037 20.2 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX87291.1 - 3.5e-05 24.3 0.1 0.00019 21.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87291.1 - 0.0015 18.1 0.0 0.058 12.9 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Pyridoxal_deC PF00282.14 KFX87291.1 - 0.013 13.9 0.0 0.023 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Methyltransf_16 PF10294.4 KFX87291.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KFX87291.1 - 0.024 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KFX87291.1 - 0.069 13.6 0.1 4.9 7.7 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KFX87291.1 - 0.077 12.0 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 KFX87291.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MFS_1 PF07690.11 KFX87292.1 - 4.5e-32 111.1 38.1 5.6e-32 110.8 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily KbaA PF14089.1 KFX87292.1 - 0.53 9.8 6.5 0.035 13.6 0.8 1.7 2 0 0 2 2 2 0 KinB-signalling pathway activation in sporulation ABC_membrane_2 PF06472.10 KFX87293.1 - 1.8e-108 361.9 2.5 3e-108 361.2 1.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFX87293.1 - 1.1e-17 64.5 0.0 2.7e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFX87293.1 - 0.00059 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX87293.1 - 0.014 15.3 0.2 0.055 13.4 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KFX87293.1 - 0.017 15.4 0.1 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KFX87293.1 - 0.045 12.9 0.2 0.23 10.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX87293.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 KFX87293.1 - 0.081 11.9 0.0 0.47 9.4 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KFX87293.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 KFX87293.1 - 0.16 11.1 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI zf-CSL PF05207.8 KFX87294.1 - 6.5e-24 83.1 0.3 7.6e-24 82.9 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.11 KFX87295.1 - 1.2e-34 118.4 0.0 1.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.15 KFX87296.1 - 1.5e-41 141.4 0.1 5.7e-41 139.5 0.0 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1 PF00133.17 KFX87298.1 - 2.9e-38 131.3 0.0 1.8e-27 95.6 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFX87298.1 - 1.4e-18 66.7 0.0 4.7e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFX87298.1 - 1.2e-11 44.5 0.1 2.7e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFX87298.1 - 9.3e-08 31.5 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Auxin_repressed PF05564.7 KFX87298.1 - 0.08 13.5 0.4 0.21 12.2 0.1 1.8 2 0 0 2 2 2 0 Dormancy/auxin associated protein tRNA-synt_1_2 PF13603.1 KFX87298.1 - 0.1 11.8 0.8 10 5.3 0.0 2.9 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 ATG16 PF08614.6 KFX87300.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 KFX87300.1 - 0.023 14.2 0.1 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 KFX87300.1 - 0.089 13.1 0.1 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 SlyX IncA PF04156.9 KFX87300.1 - 0.24 10.9 1.5 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 IncA protein Striatin PF08232.7 KFX87300.1 - 0.9 9.8 7.7 3.5 7.9 5.3 1.9 1 1 0 1 1 1 0 Striatin family Bromodomain PF00439.20 KFX87301.1 - 5.1e-14 51.9 0.0 1.6e-13 50.3 0.0 1.8 1 1 0 1 1 1 1 Bromodomain DUF2280 PF10045.4 KFX87301.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) APH PF01636.18 KFX87302.1 - 1.7e-11 44.3 0.0 8.3e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX87302.1 - 0.0011 18.5 0.0 0.0049 16.4 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KFX87302.1 - 0.054 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.11 KFX87303.1 - 6.5e-37 127.0 32.2 6.5e-37 127.0 22.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1673 PF07895.6 KFX87303.1 - 0.1 12.0 0.1 0.1 12.0 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4112 PF13430.1 KFX87303.1 - 0.17 11.8 1.8 1.9 8.4 0.2 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4112) ketoacyl-synt PF00109.21 KFX87304.1 - 8.4e-78 261.3 0.0 1.5e-77 260.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX87304.1 - 2.1e-46 158.7 0.0 2.9e-44 151.6 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFX87304.1 - 4.2e-34 116.9 0.0 1.2e-33 115.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KFX87304.1 - 6.3e-30 105.1 0.0 2e-29 103.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 KFX87304.1 - 2.7e-25 88.4 6.6 1.6e-11 44.3 0.1 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 KFX87304.1 - 4.8e-11 42.3 0.0 7.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 KFX87304.1 - 1.8e-05 24.5 0.0 0.18 11.5 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX87304.1 - 4.1e-05 23.5 0.0 0.00039 20.3 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KFX87304.1 - 0.00058 18.9 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 KFX87304.1 - 0.0056 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) ABC2_membrane PF01061.19 KFX87305.1 - 2.6e-28 98.6 28.8 2.6e-28 98.6 19.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KFX87305.1 - 7.5e-27 94.3 0.0 1.2e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFX87305.1 - 7.1e-09 36.0 0.6 2.5e-06 27.6 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX87305.1 - 4.9e-05 23.4 0.0 0.00018 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX87305.1 - 9.1e-05 22.5 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFX87305.1 - 0.0002 22.1 0.0 0.00053 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX87305.1 - 0.00035 19.8 0.0 0.00093 18.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX87305.1 - 0.00073 18.9 0.0 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX87305.1 - 0.0021 17.3 0.6 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX87305.1 - 0.0029 17.0 0.1 0.0063 16.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KFX87305.1 - 0.0036 16.4 0.0 0.4 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFX87305.1 - 0.0048 17.2 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFX87305.1 - 0.0049 17.0 0.2 0.071 13.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 KFX87305.1 - 0.014 13.9 0.5 0.24 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX87305.1 - 0.027 13.9 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KFX87305.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFX87305.1 - 0.028 13.8 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 KFX87305.1 - 0.028 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 KFX87305.1 - 0.03 14.1 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 KFX87305.1 - 0.1 11.6 26.7 0.29 10.1 18.5 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_14 PF13173.1 KFX87305.1 - 0.13 12.1 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFX87305.1 - 0.14 12.5 0.1 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFX87305.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 KFX87305.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ACOX PF01756.14 KFX87306.1 - 8.1e-35 119.8 0.1 2e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KFX87306.1 - 4.4e-25 88.3 0.0 9.6e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFX87306.1 - 1.5e-11 43.6 0.2 1.5e-11 43.6 0.2 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFX87306.1 - 2.9e-06 27.4 0.6 0.00039 20.5 0.4 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CAF-1_p150 PF11600.3 KFX87313.1 - 0.57 9.5 10.2 0.91 8.8 7.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Trypan_PARP PF05887.6 KFX87313.1 - 9.5 6.0 18.6 26 4.5 13.0 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABC2_membrane PF01061.19 KFX87315.1 - 1.5e-84 282.3 60.9 1.7e-43 148.2 14.3 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFX87315.1 - 2.7e-33 115.1 0.0 2.2e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFX87315.1 - 6.3e-32 109.3 7.9 3e-30 103.9 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KFX87315.1 - 1.8e-15 56.7 0.0 4.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KFX87315.1 - 1.3e-07 30.9 47.5 6.4e-06 25.4 12.3 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KFX87315.1 - 1.2e-06 28.1 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX87315.1 - 2e-06 27.9 0.4 0.023 14.7 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFX87315.1 - 7.9e-06 25.1 0.1 0.00024 20.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFX87315.1 - 1.1e-05 26.2 0.1 0.022 15.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX87315.1 - 3.2e-05 23.8 0.0 0.022 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX87315.1 - 5.9e-05 23.3 0.0 0.047 14.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFX87315.1 - 0.00025 20.5 0.5 0.033 13.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KFX87315.1 - 0.00035 20.5 0.2 1 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KFX87315.1 - 0.00065 19.1 0.9 0.049 13.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFX87315.1 - 0.0028 17.3 0.2 3 7.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 KFX87315.1 - 0.0041 17.2 0.4 1.1 9.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain SMC_N PF02463.14 KFX87315.1 - 0.0042 16.3 0.0 0.62 9.2 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX87315.1 - 0.0051 16.8 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KFX87315.1 - 0.011 15.3 0.8 3.3 7.3 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KFX87315.1 - 0.014 15.5 0.0 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX87315.1 - 0.11 12.2 0.1 11 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KFX87315.1 - 0.14 12.6 0.0 32 5.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KFX87315.1 - 0.25 10.9 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX87315.1 - 0.32 10.3 1.3 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Zn_clus PF00172.13 KFX87316.1 - 3.8e-07 29.9 12.7 3.8e-07 29.9 8.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX87316.1 - 0.06 12.2 0.2 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87318.1 - 2.4e-07 30.5 11.3 5.3e-07 29.4 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3123 PF11321.3 KFX87323.1 - 0.55 10.5 3.0 0.57 10.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) L71 PF02448.10 KFX87324.1 - 0.035 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 L71 family DUF4414 PF14377.1 KFX87324.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) RNA12 PF10443.4 KFX87325.1 - 2.9e-165 549.9 0.5 5e-165 549.1 0.4 1.4 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 KFX87325.1 - 0.00076 19.0 0.0 0.0069 15.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 KFX87325.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase RRM_5 PF13893.1 KFX87325.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_49kDa PF00346.14 KFX87329.1 - 1e-133 444.4 0.0 1.3e-133 444.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 KFX87330.1 - 1.7e-25 89.3 0.0 3.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFX87330.1 - 5.2e-16 57.5 0.0 7.5e-16 57.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 KFX87331.1 - 1.8e-37 128.1 0.1 5.9e-37 126.5 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KFX87331.1 - 3.7e-28 97.1 0.0 7.2e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KFX87331.1 - 9.4e-25 85.9 0.5 2.7e-24 84.5 0.4 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KFX87331.1 - 7.6e-14 50.8 3.3 7.6e-14 50.8 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KFX87331.1 - 0.00032 20.8 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.3 KFX87331.1 - 0.091 12.6 0.7 0.22 11.4 0.5 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.13 KFX87331.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Telomere_reg-2 PF10193.4 KFX87332.1 - 3.4e-39 133.6 0.0 7.7e-39 132.4 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Ras PF00071.17 KFX87334.1 - 4.5e-49 165.9 0.0 5.7e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX87334.1 - 4.2e-15 56.2 0.0 8.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX87334.1 - 2.1e-10 40.1 0.0 2.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KFX87334.1 - 0.00014 21.9 0.1 0.00074 19.6 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KFX87334.1 - 0.0023 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFX87334.1 - 0.019 13.6 1.5 0.39 9.3 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 KFX87334.1 - 0.033 13.4 0.1 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KFX87334.1 - 0.061 13.4 0.3 0.21 11.7 0.1 2.0 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 KFX87334.1 - 0.094 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain PAP2 PF01569.16 KFX87335.1 - 6.6e-05 22.6 0.2 0.00016 21.3 0.0 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KFX87335.1 - 0.037 13.7 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Divergent PAP2 family PDZ_2 PF13180.1 KFX87336.1 - 1.8e-07 30.9 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFX87336.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 KFX87336.1 - 0.0025 17.9 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DLH PF01738.13 KFX87337.1 - 2.3e-34 118.5 0.1 2.7e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX87337.1 - 3.3e-08 33.4 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX87337.1 - 0.0014 18.5 0.0 0.0055 16.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3530 PF12048.3 KFX87337.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BAAT_C PF08840.6 KFX87337.1 - 0.1 12.2 0.1 6.5 6.3 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KFX87337.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cys_Met_Meta_PP PF01053.15 KFX87339.1 - 7.9e-55 185.7 0.0 5.8e-54 182.8 0.0 2.2 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-CCCH PF00642.19 KFX87339.1 - 1.2e-06 28.0 2.2 1.2e-06 28.0 1.5 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KFX87339.1 - 0.00024 20.9 0.0 0.00057 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX87339.1 - 0.0085 15.6 0.0 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.14 KFX87339.1 - 0.054 12.2 0.0 0.088 11.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V HATPase_c_3 PF13589.1 KFX87340.1 - 3.2e-15 55.9 0.1 6.8e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KFX87340.1 - 1.2e-11 44.1 0.0 2.7e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KFX87340.1 - 4.4e-10 39.2 0.1 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase tRNA-synt_1 PF00133.17 KFX87341.1 - 3.6e-215 715.5 1.1 1.9e-214 713.1 0.8 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFX87341.1 - 7.3e-32 110.2 0.7 1.5e-31 109.2 0.5 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFX87341.1 - 1.3e-16 60.2 0.4 5.3e-08 31.9 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KFX87341.1 - 5.8e-14 51.7 0.8 7.3e-10 38.4 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KFX87341.1 - 0.0018 18.3 5.0 0.0018 18.3 3.5 2.6 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 KFX87341.1 - 0.0039 16.3 0.0 0.028 13.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KFX87341.1 - 0.015 14.1 1.4 0.9 8.2 0.0 3.2 3 0 0 3 3 3 0 tRNA synthetases class I (R) Fusion_gly PF00523.13 KFX87341.1 - 0.072 11.1 0.1 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Chitin_synth_2 PF03142.10 KFX87342.1 - 6.6e-294 975.1 0.0 9.5e-294 974.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KFX87342.1 - 4.7e-18 65.5 4.1 2e-17 63.5 2.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFX87342.1 - 9.2e-15 55.0 0.0 2.3e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KFX87342.1 - 6.4e-08 32.2 0.0 8e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KFX87342.1 - 0.0011 18.2 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFX87342.1 - 0.0039 16.9 0.0 0.062 12.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2207 PF09972.4 KFX87342.1 - 3.2 6.2 5.3 35 2.7 1.7 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Sel1 PF08238.7 KFX87343.1 - 1.2e-35 121.0 34.6 2.2e-06 28.0 0.5 8.5 8 0 0 8 8 8 7 Sel1 repeat FYVE PF01363.16 KFX87344.1 - 1e-21 76.5 1.4 1e-21 76.5 1.0 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KFX87344.1 - 7.1e-08 32.1 3.8 7.1e-08 32.1 2.7 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KFX87344.1 - 6.4e-05 22.5 2.4 6.4e-05 22.5 1.7 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX87344.1 - 0.0082 16.2 4.1 0.0082 16.2 2.8 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger Rad50_zn_hook PF04423.9 KFX87344.1 - 0.029 13.8 2.5 0.083 12.3 0.3 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FYVE_2 PF02318.11 KFX87344.1 - 0.12 12.3 10.0 0.058 13.2 1.7 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-HC5HC2H PF13771.1 KFX87344.1 - 1.1 9.3 9.1 2.1 8.5 0.8 2.9 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.1 KFX87344.1 - 2.8 8.0 31.2 0.031 14.3 3.2 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF3605 PF12239.3 KFX87345.1 - 4.6e-55 185.8 0.4 5.4e-55 185.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.13 KFX87346.1 - 2.8e-19 69.3 0.1 2.2e-15 56.7 0.1 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase FAR1 PF03101.10 KFX87346.1 - 0.00062 20.2 0.9 0.0012 19.2 0.6 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Fungal_trans PF04082.13 KFX87347.1 - 4.1e-19 68.4 0.0 7.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ING PF12998.2 KFX87348.1 - 7e-21 74.4 2.1 1e-20 73.9 1.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFX87348.1 - 6.9e-08 32.0 7.8 1.2e-07 31.2 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.13 KFX87348.1 - 0.024 13.7 0.9 0.024 13.7 0.6 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Axin_b-cat_bind PF08833.5 KFX87348.1 - 0.74 9.5 4.7 14 5.5 0.0 3.8 4 0 0 4 4 4 0 Axin beta-catenin binding domain Hist_deacetyl PF00850.14 KFX87349.1 - 1.4e-80 270.9 0.5 2.4e-80 270.1 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain tRNA-synt_His PF13393.1 KFX87350.1 - 2.8e-40 138.3 0.0 8.8e-34 116.9 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KFX87350.1 - 1.7e-18 66.8 0.0 2.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX87350.1 - 2.4e-11 43.4 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KFX87350.1 - 3.6e-05 22.6 0.0 0.00077 18.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 KFX87350.1 - 0.15 12.4 0.3 0.15 12.4 0.2 3.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein Homeobox PF00046.24 KFX87351.1 - 1.1e-13 50.5 4.1 2.2e-13 49.5 2.8 1.5 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 KFX87352.1 - 8.8e-72 241.3 0.0 1.2e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87352.1 - 7.5e-37 126.8 0.0 1.1e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX87352.1 - 1.2e-07 31.0 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFX87352.1 - 0.00047 19.5 0.0 0.0052 16.1 0.0 2.3 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KFX87352.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 KFX87353.1 - 9.7e-24 83.3 0.0 1.1e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX87353.1 - 8.7e-05 22.2 0.0 0.00013 21.7 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFX87353.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KFX87353.1 - 0.0024 17.7 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain NMO PF03060.10 KFX87357.1 - 4.3e-60 203.6 0.2 7.5e-60 202.8 0.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFX87357.1 - 3.4e-12 45.9 0.0 1.6e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFX87357.1 - 0.0017 17.2 0.1 0.0038 16.1 0.1 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFX87357.1 - 0.0074 15.2 0.1 0.016 14.1 0.1 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase DUF1902 PF08972.6 KFX87357.1 - 0.04 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) His_biosynth PF00977.16 KFX87357.1 - 0.05 12.8 0.2 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KFX87357.1 - 0.18 10.7 0.9 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NAD_binding_6 PF08030.7 KFX87358.1 - 3.4e-18 66.0 0.0 5.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFX87358.1 - 5.2e-18 65.3 12.7 3.3e-17 62.7 6.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF4405 PF14358.1 KFX87358.1 - 1.4 9.0 10.6 1.5 8.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) dsrm PF00035.20 KFX87360.1 - 0.0009 19.7 0.0 0.0017 18.8 0.0 1.4 1 1 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFX87360.1 - 0.0037 17.5 0.1 0.016 15.5 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RPA_interact_N PF14766.1 KFX87360.1 - 0.024 14.0 0.1 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Ribosomal_S7 PF00177.16 KFX87361.1 - 3.8e-25 88.1 0.0 7.2e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e APH PF01636.18 KFX87366.1 - 1.5e-17 64.1 0.0 8.5e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX87366.1 - 1.5e-07 31.2 0.0 2.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFX87366.1 - 0.0028 17.0 0.6 0.024 13.9 0.0 2.3 3 0 0 3 3 3 1 RIO1 family MFS_1 PF07690.11 KFX87367.1 - 1.8e-29 102.6 30.9 7.3e-29 100.5 21.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KFX87368.1 - 5.7e-89 298.7 0.0 7.2e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KFX87369.1 - 1.1e-21 75.8 19.8 3.7e-07 29.7 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.7 KFX87369.1 - 0.041 13.5 6.4 0.084 12.5 4.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF2A PF08662.6 KFX87369.1 - 0.052 13.2 0.0 0.94 9.1 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A FAM176 PF14851.1 KFX87369.1 - 0.98 9.0 2.6 2.4 7.8 1.8 1.6 1 0 0 1 1 1 0 FAM176 family Mg_trans_NIPA PF05653.9 KFX87370.1 - 3.7e-64 216.5 8.4 3.2e-62 210.1 3.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KFX87370.1 - 0.0005 20.2 0.3 0.0005 20.2 0.2 3.3 3 1 1 4 4 4 1 Multidrug resistance efflux transporter LysE PF01810.13 KFX87370.1 - 0.0007 18.9 1.9 0.0007 18.9 1.3 2.4 2 1 1 3 3 3 1 LysE type translocator EamA PF00892.15 KFX87370.1 - 0.0029 17.6 3.0 0.0029 17.6 2.1 4.2 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 KFX87370.1 - 0.012 14.4 5.4 0.056 12.2 0.1 2.2 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF4401 PF14351.1 KFX87370.1 - 0.095 11.6 10.9 0.37 9.7 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF4131 PF13567.1 KFX87370.1 - 1.4 8.3 4.6 4 6.8 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) TPR_11 PF13414.1 KFX87371.1 - 8.6e-10 38.1 0.6 6.2e-08 32.1 0.2 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFX87371.1 - 0.00023 20.8 3.7 0.39 10.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX87371.1 - 0.008 16.0 0.7 1 9.3 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX87371.1 - 0.0096 16.5 2.8 3 8.6 1.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX87371.1 - 0.03 13.9 0.1 5.3 6.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX87371.1 - 0.07 13.4 0.1 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX87371.1 - 0.08 12.7 0.8 1.8 8.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KFX87371.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 KFX87371.1 - 0.12 12.2 0.7 0.86 9.5 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX87371.1 - 0.15 12.5 0.5 17 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX87371.1 - 0.66 10.7 4.4 20 6.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HMG_box PF00505.14 KFX87373.1 - 0.034 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box RNase_HII PF01351.13 KFX87378.1 - 1.1e-29 103.4 0.0 2.1e-23 83.0 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII T4-Gluco-transf PF09198.5 KFX87378.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase RHD3 PF05879.7 KFX87379.1 - 0 1045.0 0.0 0 1044.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KFX87379.1 - 6.6e-08 31.9 0.1 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KFX87379.1 - 7.8e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KFX87379.1 - 0.00023 21.0 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX87379.1 - 0.0059 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KFX87379.1 - 0.0082 16.1 0.0 0.031 14.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain DSBA PF01323.15 KFX87379.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Asp PF00026.18 KFX87380.1 - 1.4e-70 238.0 6.4 1.7e-70 237.7 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX87380.1 - 1.5e-09 38.0 0.0 6.1e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX87380.1 - 0.0001 22.7 1.4 0.0043 17.5 0.3 3.1 2 1 0 2 2 2 1 Aspartyl protease Ank PF00023.25 KFX87381.1 - 3.4e-06 26.5 0.0 0.8 9.6 0.0 5.3 4 1 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 KFX87381.1 - 1.1e-05 25.6 0.1 0.064 13.5 0.0 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX87381.1 - 1.4e-05 25.4 0.2 0.61 10.6 0.0 5.1 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX87381.1 - 0.00014 21.7 0.1 50 4.5 0.0 5.9 5 0 0 5 5 5 0 Ankyrin repeat F-box-like PF12937.2 KFX87381.1 - 0.0016 18.1 0.5 0.0061 16.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFX87381.1 - 0.003 17.1 0.7 0.0066 16.0 0.0 1.8 2 0 0 2 2 2 1 F-box domain Saccharop_dh PF03435.13 KFX87382.1 - 3.5e-24 85.5 0.4 4.8e-24 85.0 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KFX87382.1 - 0.0015 18.2 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 KFX87382.1 - 0.0017 18.6 0.1 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KFX87382.1 - 0.0029 17.0 0.1 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFX87382.1 - 0.0057 16.5 0.4 0.015 15.2 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX87382.1 - 0.0057 15.5 0.1 0.0092 14.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFX87382.1 - 0.016 14.4 0.3 0.034 13.4 0.2 1.6 1 1 0 1 1 1 0 NmrA-like family Aldolase PF01081.14 KFX87382.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase Arc_PepC PF06819.6 KFX87384.1 - 0.28 11.1 2.9 0.23 11.4 0.4 2.2 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Rootletin PF15035.1 KFX87384.1 - 0.38 10.7 20.7 1.1 9.1 9.7 2.5 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.13 KFX87384.1 - 0.4 10.4 12.9 0.29 10.8 1.6 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.1 KFX87384.1 - 0.44 10.8 5.2 0.48 10.7 0.0 3.0 2 1 1 3 3 3 0 Snapin/Pallidin DUF4140 PF13600.1 KFX87384.1 - 1 9.8 13.8 0.11 12.9 2.2 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 KFX87384.1 - 1.1 9.5 26.8 2.8 8.2 0.7 3.9 2 2 0 3 3 3 0 Protein of unknown function (DUF904) LPP PF04728.8 KFX87384.1 - 1.7 8.4 5.4 6.9 6.5 0.2 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.7 KFX87384.1 - 1.7 8.3 18.9 0.34 10.6 9.1 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cwf_Cwc_15 PF04889.7 KFX87384.1 - 6.7 6.3 14.2 9.4 5.8 9.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Atg14 PF10186.4 KFX87384.1 - 7.1 5.4 19.6 0.32 9.9 5.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 KFX87384.1 - 9.5 6.6 10.4 0.66 10.3 0.3 3.2 2 1 2 4 4 4 0 SlyX MFS_1 PF07690.11 KFX87385.1 - 3.6e-34 118.0 52.0 9.5e-34 116.6 36.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2_jaz PF12171.3 KFX87386.1 - 0.00043 20.3 1.2 0.00076 19.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX87386.1 - 0.0038 17.3 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KFX87386.1 - 0.014 15.0 1.0 0.025 14.2 0.7 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.21 KFX87386.1 - 0.028 14.7 0.5 0.048 14.0 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3449 PF11931.3 KFX87386.1 - 0.04 13.4 1.1 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.1 KFX87386.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger FAD_binding_1 PF00667.15 KFX87390.1 - 1.8e-60 204.1 0.0 3e-60 203.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFX87390.1 - 1.3e-32 112.7 1.2 2.6e-32 111.7 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFX87390.1 - 6.6e-23 81.3 0.1 2.1e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KFX87390.1 - 0.069 13.1 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 Flavodoxin domain FSH1 PF03959.8 KFX87397.1 - 2e-33 115.6 0.0 2.5e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.4 KFX87397.1 - 0.00048 19.4 0.5 0.54 9.4 0.4 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KFX87397.1 - 0.0028 17.5 4.5 0.23 11.3 3.1 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KFX87397.1 - 0.028 13.8 0.5 0.069 12.5 0.1 1.8 1 1 1 2 2 2 0 PE-PPE domain AXE1 PF05448.7 KFX87397.1 - 0.046 12.2 0.8 0.64 8.4 0.1 2.3 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 KFX87397.1 - 0.068 12.9 6.0 9.8 5.9 4.1 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pec_lyase_N PF04431.8 KFX87398.1 - 0.01 15.9 0.4 0.019 15.0 0.3 1.5 1 1 0 1 1 1 1 Pectate lyase, N terminus FAD_binding_3 PF01494.14 KFX87400.1 - 8.5e-13 48.0 0.0 2.1e-07 30.3 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFX87400.1 - 0.00095 19.1 0.1 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX87400.1 - 0.004 17.0 0.1 0.0081 16.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Poxvirus_B22R_C PF13168.1 KFX87400.1 - 0.019 14.2 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal FAD_binding_2 PF00890.19 KFX87400.1 - 0.021 13.7 0.1 0.09 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX87400.1 - 0.044 13.5 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KFX87400.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KFX87400.1 - 0.087 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KFX87400.1 - 0.11 12.5 0.3 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Lipoxygenase PF00305.14 KFX87402.1 - 2.5e-61 207.5 1.0 6.4e-61 206.2 0.7 1.5 1 1 0 1 1 1 1 Lipoxygenase ERG4_ERG24 PF01222.12 KFX87403.1 - 0.018 13.6 1.2 0.026 13.0 0.8 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_18 PF12847.2 KFX87405.1 - 3.9e-11 43.5 0.0 8.1e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX87405.1 - 7.1e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87405.1 - 4.1e-05 23.2 0.1 0.00092 18.8 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX87405.1 - 0.00013 22.2 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX87405.1 - 0.00048 19.7 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KFX87405.1 - 0.0012 19.2 0.0 0.014 15.8 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain MetW PF07021.7 KFX87405.1 - 0.0032 16.8 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW GCD14 PF08704.5 KFX87405.1 - 0.0046 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 KFX87405.1 - 0.0065 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFX87405.1 - 0.023 15.1 0.0 0.062 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.12 KFX87405.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.14 KFX87405.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFX87405.1 - 0.1 12.0 0.1 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Zn_clus PF00172.13 KFX87406.1 - 3e-06 27.0 11.6 3e-06 27.0 8.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 KFX87407.1 - 1.1e-13 51.1 0.0 2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX87407.1 - 2.6e-11 43.5 0.0 5.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX87407.1 - 4.8e-10 39.2 0.1 1.8e-09 37.4 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX87407.1 - 3.8e-09 36.4 0.0 6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX87407.1 - 3.8e-06 27.3 0.0 6.4e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX87407.1 - 6.3e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans_2 PF11951.3 KFX87408.1 - 3.2e-62 210.3 1.3 5.4e-62 209.5 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.20 KFX87409.1 - 1.2e-07 31.7 0.2 4e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX87409.1 - 2.7e-05 23.9 0.0 0.00046 19.8 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFX87409.1 - 0.00086 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase VWA_2 PF13519.1 KFX87410.1 - 0.00036 20.6 0.0 0.00076 19.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX87410.1 - 0.0021 17.8 0.0 0.0062 16.2 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans PF04082.13 KFX87411.1 - 9.6e-16 57.4 0.0 1.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87411.1 - 5.5e-09 35.7 8.8 5.5e-09 35.7 6.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 KFX87412.1 - 2e-30 105.7 0.5 2.3e-30 105.5 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX87412.1 - 3.6e-16 59.6 0.3 7.8e-16 58.6 0.1 1.6 1 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KFX87412.1 - 2.7e-05 23.7 0.1 0.002 17.6 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KFX87412.1 - 0.00035 20.9 2.3 0.00048 20.4 0.2 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 KFX87412.1 - 0.00036 19.3 0.6 0.0014 17.4 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFX87412.1 - 0.00084 19.6 0.4 0.0021 18.3 0.1 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX87412.1 - 0.013 15.4 2.6 0.03 14.2 0.4 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KFX87412.1 - 0.058 12.2 0.2 0.14 11.0 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PAN_4 PF14295.1 KFX87413.1 - 0.00011 21.7 22.5 0.0068 16.0 1.3 3.3 2 1 1 3 3 3 2 PAN domain MANEC PF07502.9 KFX87413.1 - 0.0037 17.2 7.2 0.33 10.9 1.1 2.5 2 0 0 2 2 2 2 MANEC domain PAN_3 PF08277.7 KFX87413.1 - 3.1 7.5 12.1 5.6 6.6 4.3 3.0 2 1 0 2 2 2 0 PAN-like domain NmrA PF05368.8 KFX87414.1 - 2.1e-07 30.4 0.0 2.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX87414.1 - 1.1e-06 28.7 0.1 2.2e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX87414.1 - 0.0099 16.1 0.9 0.037 14.3 0.2 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX87414.1 - 0.014 15.2 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 KFX87414.1 - 0.031 13.6 0.2 0.065 12.6 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Antig_Caf1 PF09255.5 KFX87414.1 - 0.063 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Caf1 Capsule antigen COX8 PF02285.10 KFX87414.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII Fungal_trans_2 PF11951.3 KFX87415.1 - 1.4e-61 208.1 2.1 1.9e-61 207.7 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87415.1 - 1.1e-07 31.5 5.2 1.1e-07 31.5 3.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX87416.1 - 2.8e-74 250.3 21.3 3.4e-74 250.0 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87416.1 - 9e-23 80.5 26.5 9.5e-23 80.4 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 KFX87416.1 - 0.99 9.3 6.0 14 5.7 0.1 2.9 2 0 0 2 2 2 0 YtpI-like protein GFA PF04828.9 KFX87417.1 - 4.5e-19 68.1 0.5 7.7e-19 67.4 0.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 KFX87417.1 - 0.098 12.3 0.0 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit NOB1_Zn_bind PF08772.6 KFX87417.1 - 0.5 10.2 3.4 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Beta_helix PF13229.1 KFX87418.1 - 1.5e-08 34.5 14.0 7.2e-05 22.5 3.7 2.7 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.1 KFX87418.1 - 2.5e-06 26.6 0.0 4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Chondroitinase B GMC_oxred_C PF05199.8 KFX87419.1 - 5.6e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Glyco_hydro_43 PF04616.9 KFX87419.1 - 1.5e-10 40.6 0.1 2.4e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KFX87420.1 - 4.8e-17 61.7 0.1 7.2e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87420.1 - 0.023 14.6 3.8 0.051 13.4 2.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX87421.1 - 3.1e-96 322.6 30.2 3.9e-96 322.3 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87421.1 - 7.4e-25 87.3 21.1 7.4e-25 87.3 14.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 KFX87421.1 - 0.024 12.8 11.1 0.027 12.5 3.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Sulfatase PF00884.18 KFX87422.1 - 1.2e-43 149.5 0.2 1.1e-23 83.8 0.0 2.7 2 1 1 3 3 3 2 Sulfatase Phosphodiest PF01663.17 KFX87422.1 - 7.9e-07 28.7 0.0 1.9e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KFX87422.1 - 0.022 15.0 0.1 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Beta_helix PF13229.1 KFX87423.1 - 1.2e-11 44.6 19.0 2.6e-07 30.5 4.6 2.9 1 1 1 2 2 2 2 Right handed beta helix region zf-C2H2_2 PF12756.2 KFX87424.1 - 5.2e-30 103.5 11.9 3.5e-22 78.4 2.1 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFX87424.1 - 0.0001 22.3 14.6 0.00053 20.0 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding F-box-like PF12937.2 KFX87424.1 - 0.0049 16.5 0.2 0.016 14.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like zf-met PF12874.2 KFX87424.1 - 0.0073 16.4 12.0 0.13 12.4 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KFX87424.1 - 1.2 9.5 13.2 0.84 10.1 1.0 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX87424.1 - 2.8 8.4 15.9 2.2 8.8 0.8 4.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KFX87424.1 - 7.7 6.5 12.7 4.9 7.2 1.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1180 PF06679.7 KFX87425.1 - 0.0011 18.8 0.7 0.18 11.6 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) Podoplanin PF05808.6 KFX87425.1 - 0.018 14.5 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.1 KFX87425.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF1517 PF07466.6 KFX87425.1 - 0.14 11.0 1.1 0.23 10.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Adeno_E3_CR2 PF02439.10 KFX87426.1 - 0.00011 21.6 0.4 0.00022 20.7 0.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Asp PF00026.18 KFX87426.1 - 0.00084 18.6 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Herpes_gE PF02480.11 KFX87426.1 - 0.082 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3 PF06040.6 KFX87426.1 - 0.11 12.4 0.9 5.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Adenovirus E3 protein NAD_binding_10 PF13460.1 KFX87430.1 - 3.6e-06 27.0 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX87430.1 - 5.9e-06 25.8 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX87430.1 - 5.9e-05 23.3 0.0 9.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KFX87430.1 - 6.3e-05 22.0 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KFX87430.1 - 0.00013 21.2 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFX87430.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cutinase PF01083.17 KFX87432.1 - 2.2e-49 167.5 12.2 2.6e-49 167.3 8.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFX87432.1 - 7.1e-05 22.3 0.5 0.00011 21.6 0.2 1.4 1 1 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.3 KFX87432.1 - 0.0058 15.8 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) GHMP_kinases_N PF00288.21 KFX87432.1 - 0.047 13.7 1.4 0.45 10.6 0.7 2.3 2 0 0 2 2 2 0 GHMP kinases N terminal domain Response_reg PF00072.19 KFX87433.1 - 2.2e-21 75.9 0.0 2.9e-20 72.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KFX87433.1 - 6.8e-21 74.0 0.1 1.3e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFX87433.1 - 7e-12 45.1 0.1 2e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KFX87433.1 - 3.7e-05 23.8 0.0 0.00014 21.9 0.0 2.1 2 0 0 2 2 2 1 GAF domain MS_channel PF00924.13 KFX87433.1 - 0.032 13.5 0.0 0.098 11.9 0.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel Abhydrolase_6 PF12697.2 KFX87434.1 - 9.2e-21 74.7 0.0 1.3e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX87434.1 - 4.4e-08 32.9 0.0 6.7e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX87434.1 - 0.0013 18.3 0.0 0.0076 15.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KFX87434.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 KFX87434.1 - 0.0024 17.1 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PE-PPE PF08237.6 KFX87434.1 - 0.055 12.8 0.1 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Lipase_2 PF01674.13 KFX87434.1 - 0.16 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) Cys_Met_Meta_PP PF01053.15 KFX87435.1 - 2.2e-134 447.6 0.0 2.5e-134 447.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFX87435.1 - 1.8e-07 30.4 0.0 2.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 KFX87435.1 - 2.5e-05 22.7 0.0 8.6e-05 21.0 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 KFX87435.1 - 3.5e-05 22.7 0.0 8.4e-05 21.4 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFX87435.1 - 0.0011 18.1 0.0 0.0034 16.4 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KFX87435.1 - 0.0021 17.2 0.0 0.016 14.3 0.0 2.0 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 KFX87435.1 - 0.0031 17.1 0.0 0.0087 15.7 0.0 1.7 1 0 0 1 1 1 1 POTRA domain, ShlB-type PGI PF00342.14 KFX87436.1 - 5.2e-217 721.0 2.8 5.9e-217 720.8 1.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase TFIIE-A_C-term PF11521.3 KFX87437.1 - 0.083 12.8 1.5 0.11 12.4 1.1 1.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha HAD_2 PF13419.1 KFX87439.1 - 1.6e-30 106.6 0.0 1.8e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX87439.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Consortin_C PF15281.1 KFX87440.1 - 0.34 10.4 2.5 0.62 9.5 1.7 1.5 1 0 0 1 1 1 0 Consortin C-terminus AIG2 PF06094.7 KFX87441.1 - 2.8e-10 40.5 0.0 3.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Aldose_epim PF01263.15 KFX87442.1 - 2.2e-60 204.3 0.0 2.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.3 KFX87443.1 - 9.9e-33 112.3 0.4 1.9e-32 111.3 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.7 KFX87444.1 - 1.1e-152 508.1 0.0 1.6e-152 507.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) NMT1 PF09084.6 KFX87444.1 - 1.8e-75 253.2 0.0 9.1e-75 250.9 0.0 2.0 2 0 0 2 2 2 1 NMT1/THI5 like DNA_pol_B_exo1 PF03104.14 KFX87444.1 - 2e-64 217.4 0.4 3.6e-64 216.6 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KFX87444.1 - 4.1e-21 75.3 0.1 2.2e-20 72.9 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KFX87444.1 - 1.4e-09 37.7 0.2 4.3e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KFX87444.1 - 1.4e-05 24.9 0.0 5.8e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily NMT1_2 PF13379.1 KFX87444.1 - 0.002 17.5 1.4 0.73 9.1 0.0 3.4 2 1 0 3 3 3 1 NMT1-like family FtsJ PF01728.14 KFX87445.1 - 4e-11 43.2 0.0 6.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFX87445.1 - 0.067 13.7 0.0 3.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain adh_short PF00106.20 KFX87446.1 - 2.9e-06 27.2 0.1 3.1e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX87446.1 - 0.0042 16.7 0.0 0.0044 16.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFX87446.1 - 0.093 12.5 0.8 0.14 11.9 0.5 1.2 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cutinase PF01083.17 KFX87448.1 - 1.6e-53 181.1 8.4 2.3e-53 180.5 5.9 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 KFX87448.1 - 6.5e-12 44.9 15.4 6.5e-12 44.9 10.7 4.0 3 1 1 4 4 4 1 Fungal cellulose binding domain PE-PPE PF08237.6 KFX87448.1 - 0.00013 21.4 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Toxin_7 PF05980.7 KFX87448.1 - 0.086 12.8 0.6 0.086 12.8 0.4 3.2 2 1 1 3 3 3 0 Toxin 7 Abhydrolase_6 PF12697.2 KFX87448.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.19 KFX87449.1 - 1.3e-29 103.2 0.9 1.9e-29 102.7 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX87449.1 - 2.5e-22 78.1 0.5 5.4e-22 77.0 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX87449.1 - 1.2e-19 70.9 0.0 2.7e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFX87449.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CFEM PF05730.6 KFX87450.1 - 8.9e-10 38.2 13.2 1.5e-09 37.5 9.2 1.4 1 0 0 1 1 1 1 CFEM domain DUF566 PF04484.7 KFX87450.1 - 4.4 6.7 5.8 5.1 6.5 4.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pex14_N PF04695.8 KFX87450.1 - 7.9 6.5 7.6 20 5.2 5.3 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NUDIX PF00293.23 KFX87451.1 - 7.5e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Yae1_N PF09811.4 KFX87453.1 - 2.1e-11 43.1 1.4 3.6e-11 42.4 1.0 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 KFX87453.1 - 0.017 15.2 0.8 0.032 14.4 0.5 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF718 PF05336.8 KFX87454.1 - 1.3e-33 114.9 0.1 1.8e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF718) HpaP PF09483.5 KFX87454.1 - 0.11 12.4 5.2 0.15 12.0 3.6 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) MSA-2c PF12238.3 KFX87454.1 - 0.5 10.0 2.7 0.74 9.4 1.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Thioredoxin PF00085.15 KFX87455.1 - 4.5e-08 32.7 0.0 6.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFX87455.1 - 0.0078 16.3 0.0 0.087 12.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Tubulin_2 PF13809.1 KFX87455.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Thioredoxin_2 PF13098.1 KFX87455.1 - 0.12 12.6 0.0 0.85 9.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 KFX87456.1 - 3.1e-37 128.1 26.7 3.5e-28 98.3 6.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX87456.1 - 2.2e-12 46.3 13.6 2.2e-12 46.3 9.4 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter UPF0016 PF01169.14 KFX87457.1 - 1.1e-42 144.0 24.0 1.2e-21 76.6 4.9 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-bind_6 PF13921.1 KFX87458.1 - 0.00025 21.1 0.1 0.00062 19.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX87458.1 - 0.0012 18.8 0.3 0.0025 17.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFX87458.1 - 0.033 14.2 1.4 0.39 10.8 0.0 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Nucleoplasmin PF03066.10 KFX87462.1 - 0.016 14.7 3.4 0.016 14.7 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 KFX87462.1 - 0.11 10.3 2.9 0.088 10.7 2.0 1.1 1 0 0 1 1 1 0 Nop14-like family SAP PF02037.22 KFX87463.1 - 0.016 14.7 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 SAP domain Ish1 PF10281.4 KFX87463.1 - 0.12 12.4 1.2 0.26 11.4 0.8 1.7 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Ribosomal_L38e PF01781.13 KFX87464.1 - 2.2e-32 110.6 2.5 2.6e-32 110.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family APH PF01636.18 KFX87469.1 - 2.3e-09 37.3 0.0 5.5e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family SWIB PF02201.13 KFX87485.1 - 4.3e-27 93.6 1.4 2.8e-26 91.0 0.1 2.5 3 0 0 3 3 3 1 SWIB/MDM2 domain DEK_C PF08766.6 KFX87485.1 - 4.2e-14 52.0 0.5 1.1e-13 50.6 0.3 1.8 2 0 0 2 2 2 1 DEK C terminal domain Pkinase PF00069.20 KFX87486.1 - 1.1e-43 149.2 0.0 1.6e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KFX87486.1 - 1.8e-43 147.4 0.0 3.5e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 KFX87486.1 - 2.3e-23 82.6 0.0 2.6e-21 75.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 KFX87486.1 - 0.00033 20.1 0.8 0.0082 15.6 0.3 2.7 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 KFX87486.1 - 0.0024 17.3 2.6 0.012 15.0 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat APH PF01636.18 KFX87486.1 - 0.0086 15.8 0.3 0.032 13.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX87486.1 - 0.0091 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFX87486.1 - 0.032 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.19 KFX87487.1 - 1.1e-131 439.8 10.3 1.3e-131 439.6 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 KFX87487.1 - 0.18 11.9 1.8 0.43 10.7 0.1 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain eIF2A PF08662.6 KFX87488.1 - 2.2e-37 128.6 3.4 5.9e-36 123.9 0.2 3.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KFX87488.1 - 1.4e-06 27.8 0.0 2.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX87488.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX87488.1 - 0.00024 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFX87488.1 - 0.0017 18.1 1.4 0.095 12.6 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Far-17a_AIG1 PF04750.9 KFX87489.1 - 1.9e-59 200.2 13.5 2.2e-59 200.0 9.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pro_isomerase PF00160.16 KFX87490.1 - 1.8e-51 174.3 0.2 3.7e-51 173.4 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KFX87490.1 - 1.1e-13 50.5 0.2 8.7e-08 31.7 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KFX87491.1 - 1.5e-56 191.6 0.4 2.2e-56 191.1 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87491.1 - 4.3e-08 32.9 8.0 7.7e-08 32.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KFX87492.1 - 1.1e-93 313.8 0.0 1.4e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX87492.1 - 6.3e-12 46.2 0.2 1.8e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.6 KFX87493.1 - 3.4e-88 295.6 0.0 3.9e-88 295.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein RHH_1 PF01402.16 KFX87493.1 - 0.82 9.6 2.6 2.1 8.3 0.3 2.7 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family DUF3437 PF11919.3 KFX87497.1 - 7.1e-33 112.1 0.0 1.4e-32 111.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Ipi1_N PF12333.3 KFX87497.1 - 0.082 12.8 0.0 3.6 7.6 0.0 2.1 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 KFX87497.1 - 0.66 10.5 4.8 3.9 8.0 0.0 2.8 2 2 1 3 3 3 0 HEAT-like repeat HEAT PF02985.17 KFX87497.1 - 0.92 9.7 8.1 1 9.6 0.0 3.1 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L24e PF01246.15 KFX87499.1 - 1.1e-28 98.8 3.1 2.1e-28 97.9 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.8 KFX87500.1 - 4e-08 33.0 0.2 6.5e-08 32.4 0.1 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.26 KFX87500.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.1 KFX87500.1 - 0.0094 15.2 2.0 0.0094 15.2 1.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) TMP_2 PF06791.8 KFX87500.1 - 0.11 12.0 1.9 0.13 11.8 1.3 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein MbtH PF03621.8 KFX87502.1 - 0.076 12.3 0.5 0.15 11.4 0.3 1.4 1 0 0 1 1 1 0 MbtH-like protein Ldh_1_C PF02866.13 KFX87504.1 - 2.2e-07 30.7 0.0 2.3e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TRAPP PF04051.11 KFX87505.1 - 5.7e-45 152.5 0.0 7e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.1 KFX87506.1 - 3.5e-39 134.1 0.1 6.4e-39 133.3 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFX87506.1 - 2.7e-21 74.7 5.6 5.5e-21 73.8 3.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFX87506.1 - 1.9e-05 24.0 1.3 4.8e-05 22.8 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 KFX87506.1 - 0.014 14.9 0.7 0.054 13.0 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 KFX87506.1 - 0.36 10.7 2.3 0.83 9.5 1.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Phosphodiest PF01663.17 KFX87507.1 - 2.1e-17 63.5 2.6 1.6e-16 60.5 1.8 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2423 PF10338.4 KFX87507.1 - 2e-14 53.2 0.5 4.2e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Sulfatase PF00884.18 KFX87507.1 - 2.9e-05 23.4 0.1 7.7e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KFX87507.1 - 0.00027 20.3 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Peptidase_M9_N PF08453.5 KFX87507.1 - 0.085 12.1 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M9 N-terminal DUF229 PF02995.12 KFX87507.1 - 0.17 10.2 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) CCDC71L PF15374.1 KFX87509.1 - 6.6 5.9 8.6 7.6 5.7 5.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L N-SET PF11764.3 KFX87510.1 - 0.028 14.3 0.1 0.033 14.0 0.1 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N P16-Arc PF04699.9 KFX87511.1 - 1.3e-09 38.2 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Lipase_3 PF01764.20 KFX87514.1 - 3.8e-18 65.4 0.0 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Acetyltransf_7 PF13508.1 KFX87515.1 - 2.8e-11 43.4 0.2 5.2e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX87515.1 - 3.6e-11 42.9 0.1 6.6e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Tetraspannin PF00335.15 KFX87515.1 - 7e-09 35.2 5.4 1.1e-08 34.5 3.7 1.3 1 0 0 1 1 1 1 Tetraspanin family Acetyltransf_9 PF13527.1 KFX87515.1 - 0.00094 19.0 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX87515.1 - 0.012 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2721 PF11026.3 KFX87515.1 - 0.28 10.8 5.2 0.58 9.7 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) zf-RING_2 PF13639.1 KFX87516.1 - 8.5e-14 51.1 2.9 1.2e-13 50.5 2.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX87516.1 - 3.5e-09 36.6 0.4 5.2e-09 36.0 0.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX87516.1 - 5.6e-08 32.6 1.6 1.2e-07 31.6 1.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX87516.1 - 1.9e-07 30.6 1.4 2.7e-07 30.1 1.0 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFX87516.1 - 2.2e-06 27.2 0.3 4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFX87516.1 - 2.7e-06 26.9 1.8 5.3e-06 25.9 1.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX87516.1 - 2.8e-05 23.6 1.0 7.1e-05 22.3 0.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX87516.1 - 0.0015 18.3 2.6 0.0083 15.9 1.8 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KFX87516.1 - 0.01 15.7 2.9 0.029 14.3 2.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 KFX87516.1 - 0.031 14.1 1.4 0.077 12.8 0.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KFX87516.1 - 0.38 10.3 1.6 1.3 8.6 1.2 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 KFX87516.1 - 0.4 10.2 4.8 0.22 11.1 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFX87516.1 - 0.59 9.7 7.1 11 5.6 5.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF4243 PF14027.1 KFX87520.1 - 2.5e-83 280.2 1.4 3.3e-83 279.8 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) CBM_5_12 PF02839.9 KFX87521.1 - 0.079 12.5 0.2 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain DUF1370 PF07114.6 KFX87521.1 - 0.16 11.1 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) AMP-binding PF00501.23 KFX87522.1 - 1.4e-68 231.2 0.0 2e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 KFX87522.1 - 2.6e-29 101.8 0.1 7.2e-29 100.4 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX87522.1 - 1.6e-06 27.9 8.7 4.6e-06 26.4 6.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding_C PF13193.1 KFX87522.1 - 6.7e-05 23.7 0.0 0.00017 22.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 KFX87523.1 - 6.1e-69 231.9 0.5 1e-68 231.1 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX87523.1 - 1.1e-44 150.7 0.4 2.7e-44 149.5 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFX87523.1 - 0.0029 17.2 0.2 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KFX87523.1 - 0.032 13.7 2.4 0.3 10.5 2.1 2.2 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KFX87523.1 - 0.037 14.0 0.4 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MFS_1 PF07690.11 KFX87524.1 - 3.9e-37 127.7 22.5 5.4e-37 127.3 15.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.3 KFX87524.1 - 0.057 12.6 0.5 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Vps26 PF03643.10 KFX87527.1 - 4.3e-128 425.8 0.7 5e-128 425.6 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFX87527.1 - 0.0011 18.7 0.7 3.4 7.4 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Fungal_trans_2 PF11951.3 KFX87530.1 - 7.6e-06 24.7 0.0 1.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX87531.1 - 1.3e-34 119.4 57.6 6.5e-33 113.9 9.4 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX87531.1 - 5e-11 41.8 6.0 5e-11 41.8 4.2 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX87531.1 - 0.00059 18.3 5.9 0.00059 18.3 4.1 3.1 3 1 0 3 3 3 1 MFS/sugar transport protein LCE PF14672.1 KFX87532.1 - 0.078 13.4 1.6 0.11 12.9 1.1 1.2 1 0 0 1 1 1 0 Late cornified envelope zf-H2C2_2 PF13465.1 KFX87536.1 - 6.9e-23 79.7 23.3 3.2e-07 30.3 0.7 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFX87536.1 - 3.5e-21 74.2 25.3 5.2e-05 23.3 1.9 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX87536.1 - 9.6e-16 56.8 24.9 0.00018 21.5 0.2 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX87536.1 - 7.1e-06 26.0 8.4 0.54 10.4 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX87536.1 - 1.3e-05 25.2 10.3 0.059 13.6 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFX87536.1 - 0.0013 18.5 16.9 0.15 12.0 0.5 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger C1_4 PF07975.7 KFX87536.1 - 0.067 13.2 0.5 4.3 7.4 0.0 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 KFX87536.1 - 0.075 12.7 9.1 2.5 7.8 0.8 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type XPA_N PF01286.13 KFX87536.1 - 0.14 11.8 0.3 0.14 11.8 0.2 3.4 4 0 0 4 4 4 0 XPA protein N-terminal zf-Di19 PF05605.7 KFX87536.1 - 0.32 11.1 8.9 5.8 7.1 0.1 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFX87536.1 - 3.6 7.3 7.1 1.4 8.6 0.9 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FBPase PF00316.15 KFX87537.1 - 2.9e-124 414.1 0.0 3.4e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DnaJ PF00226.26 KFX87539.1 - 9.4e-22 76.5 0.2 3.2e-21 74.8 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain RestrictionSfiI PF11487.3 KFX87539.1 - 0.0091 15.1 0.9 0.016 14.4 0.6 1.3 1 0 0 1 1 1 1 Type II restriction enzyme SfiI RPT PF13446.1 KFX87539.1 - 0.086 12.2 1.2 3 7.3 0.0 2.5 2 0 0 2 2 2 0 A repeated domain in UCH-protein UPF0223 PF05256.7 KFX87539.1 - 0.4 10.8 4.5 1.1 9.4 2.5 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) Glyco_hydro_81 PF03639.8 KFX87540.1 - 1.1e-209 698.0 4.4 1.3e-209 697.7 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 KFX87541.1 - 2.2e-201 670.8 56.6 2.2e-201 670.8 39.2 2.1 1 1 0 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 KFX87542.1 - 5e-19 67.9 0.2 6.4e-19 67.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.20 KFX87543.1 - 1.9e-84 283.5 0.0 3.3e-84 282.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KFX87543.1 - 0.0074 15.8 0.1 0.025 14.1 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.17 KFX87544.1 - 2.3e-81 267.4 4.5 7.2e-22 76.8 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX87544.1 - 1.3e-53 178.8 0.4 3.2e-16 59.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX87544.1 - 5.5e-37 125.4 0.1 1.3e-07 31.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFX87544.1 - 1.1e-28 98.6 0.6 1.1e-28 98.6 0.4 3.1 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KFX87544.1 - 4.5e-06 26.3 3.0 0.22 11.2 0.1 3.8 2 1 1 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 KFX87544.1 - 2.9e-05 24.1 5.8 1.2 9.4 0.0 4.8 5 0 0 5 5 4 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 KFX87544.1 - 0.011 15.1 1.2 5 6.7 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KFX87544.1 - 0.013 15.2 0.1 40 4.0 0.0 3.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 KFX87544.1 - 0.35 8.8 11.6 0.55 8.1 8.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KFX87544.1 - 0.57 10.0 21.0 1.3 8.8 14.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med8 PF10232.4 KFX87544.1 - 0.67 9.4 7.9 1.5 8.2 5.5 1.6 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Phyto_Pns9_10 PF05878.6 KFX87544.1 - 1.1 8.1 8.2 2.4 7.0 5.7 1.6 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 RNA_polI_A34 PF08208.6 KFX87544.1 - 1.8 8.2 26.3 3.7 7.1 18.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 KFX87544.1 - 2.8 7.8 11.4 4.6 7.1 7.9 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 KFX87544.1 - 3.2 7.7 24.4 0.087 12.8 12.0 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 KFX87544.1 - 3.3 6.6 4.1 6.2 5.7 2.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 KFX87544.1 - 6.3 4.3 13.8 9.3 3.8 9.6 1.2 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 KFX87544.1 - 9.1 6.0 11.4 19 4.9 7.9 1.5 1 0 0 1 1 1 0 DDHD domain CENP-O PF09496.5 KFX87545.1 - 2.7e-22 78.7 0.0 6.4e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DUF2348 PF09807.4 KFX87545.1 - 6.6e-14 51.6 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KFX87545.1 - 0.0093 15.1 0.0 0.032 13.3 0.0 1.8 2 0 0 2 2 2 1 KaiC Ribosomal_L37e PF01907.14 KFX87546.1 - 9.3e-27 92.5 10.2 1.4e-26 91.9 7.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KFX87546.1 - 0.0027 17.4 0.4 0.0039 16.9 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KFX87546.1 - 0.0077 15.4 0.5 0.013 14.7 0.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 KFX87546.1 - 0.064 12.9 0.4 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 KFX87546.1 - 0.17 11.6 1.5 0.27 11.0 1.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon zinc_ribbon_2 PF13240.1 KFX87546.1 - 0.5 9.9 3.3 2.8 7.5 2.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Prefoldin PF02996.12 KFX87547.1 - 0.00049 19.7 12.8 0.00073 19.1 1.6 3.5 2 1 1 3 3 3 1 Prefoldin subunit Fez1 PF06818.10 KFX87547.1 - 0.023 14.7 12.3 0.043 13.8 8.5 1.5 1 0 0 1 1 1 0 Fez1 Reo_sigmaC PF04582.7 KFX87547.1 - 0.049 12.8 4.1 0.048 12.8 0.3 2.1 2 1 0 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFX87547.1 - 0.086 11.2 8.4 0.072 11.5 5.0 1.3 1 1 0 1 1 1 0 AAA domain IncA PF04156.9 KFX87547.1 - 0.087 12.4 22.3 0.082 12.4 7.7 2.5 2 1 0 2 2 2 0 IncA protein ERM PF00769.14 KFX87547.1 - 0.16 11.4 15.0 0.16 11.5 1.5 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Rootletin PF15035.1 KFX87547.1 - 0.27 11.1 13.2 0.53 10.2 7.2 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4613 PF15390.1 KFX87547.1 - 0.34 9.0 4.0 0.41 8.7 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Baculo_PEP_C PF04513.7 KFX87547.1 - 0.35 10.6 3.9 0.71 9.7 0.7 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KFX87547.1 - 0.44 10.3 16.2 0.32 10.7 3.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KFX87547.1 - 0.55 10.0 6.2 5.4 6.8 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.11 KFX87547.1 - 0.98 9.6 7.5 16 5.7 5.2 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 BLOC1_2 PF10046.4 KFX87547.1 - 1.4 9.0 8.2 0.47 10.6 2.4 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 KFX87547.1 - 1.5 9.1 4.8 3 8.1 0.5 3.1 2 1 0 3 3 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.6 KFX87547.1 - 1.7 9.1 16.4 7.3 7.0 2.3 3.5 2 1 0 2 2 2 0 MerR, DNA binding Osmo_CC PF08946.5 KFX87547.1 - 1.7 8.7 7.3 6.9 6.7 0.7 3.5 2 1 1 3 3 3 0 Osmosensory transporter coiled coil DUF3552 PF12072.3 KFX87547.1 - 1.7 7.7 16.5 0.08 12.1 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) V_ATPase_I PF01496.14 KFX87547.1 - 2.4 5.9 6.4 0.86 7.3 2.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 KFX87547.1 - 2.5 7.8 10.4 0.8 9.4 1.9 2.7 2 2 1 3 3 2 0 Laminin Domain II Syntaxin PF00804.20 KFX87547.1 - 2.9 8.1 8.8 1.4 9.1 3.1 2.7 1 1 1 2 2 2 0 Syntaxin DUF4200 PF13863.1 KFX87547.1 - 4.4 7.2 15.2 5.6 6.9 3.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 KFX87547.1 - 4.5 5.8 14.8 1.6 7.2 3.9 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 KFX87547.1 - 4.7 7.0 15.4 14 5.4 1.6 3.4 2 1 1 3 3 3 0 Prefoldin subunit Mod_r PF07200.8 KFX87547.1 - 4.8 7.0 15.0 0.92 9.4 3.4 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RRF_GI PF12614.3 KFX87547.1 - 8.7 6.1 10.9 0.83 9.4 0.7 2.8 2 1 1 3 3 3 0 Ribosome recycling factor Septin PF00735.13 KFX87549.1 - 2.8e-32 111.8 0.0 3.7e-11 42.5 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 KFX87549.1 - 0.0029 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 KFX87549.1 - 0.034 12.8 0.0 0.034 12.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 KFX87549.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KFX87549.1 - 0.051 13.3 1.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family A_deaminase PF00962.17 KFX87554.1 - 7.2e-45 153.3 0.0 1.1e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase SRP40_C PF05022.7 KFX87555.1 - 4.1e-24 84.8 0.7 4.1e-24 84.8 0.5 2.4 3 0 0 3 3 3 1 SRP40, C-terminal domain Sec3_C PF09763.4 KFX87556.1 - 6.5e-209 695.5 4.1 8.8e-209 695.1 2.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 p450 PF00067.17 KFX87556.1 - 1.6e-39 135.7 0.0 5.2e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Sec3-PIP2_bind PF15277.1 KFX87556.1 - 7e-30 102.7 0.0 1.6e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KFX87556.1 - 0.055 13.6 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DHBP_synthase PF00926.14 KFX87557.1 - 2.5e-69 232.4 0.0 7.7e-69 230.8 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 KFX87558.1 - 1.1e-17 64.2 0.0 1.8e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX87558.1 - 4.3e-17 62.3 0.0 7.4e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87558.1 - 5.7e-15 55.2 0.0 7.7e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX87558.1 - 2.7e-14 53.4 0.0 5.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX87558.1 - 9.2e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFX87558.1 - 3.7e-07 29.1 0.0 5.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KFX87558.1 - 4.3e-07 29.9 0.0 3.2e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX87558.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX87558.1 - 1.9e-06 27.2 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFX87558.1 - 2.4e-05 23.5 0.0 3.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KFX87558.1 - 0.00038 19.8 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 KFX87558.1 - 0.00062 18.9 0.0 0.0017 17.4 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KFX87558.1 - 0.0024 17.2 0.0 0.0043 16.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KFX87558.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CRC_subunit PF08624.5 KFX87560.1 - 2.8e-54 182.7 0.0 4e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.14 KFX87561.1 - 2.7e-93 312.8 0.4 5.1e-93 311.9 0.3 1.5 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KFX87561.1 - 5.8e-09 36.1 0.2 4e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 PIN domain TEBP_beta PF07404.6 KFX87566.1 - 0.068 12.2 0.5 0.086 11.9 0.4 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Zn_clus PF00172.13 KFX87567.1 - 9.4e-05 22.2 10.4 0.00015 21.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Malic_M PF03949.10 KFX87569.1 - 4.2e-86 288.6 0.0 5.7e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFX87569.1 - 4.4e-63 212.1 0.0 6.6e-63 211.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF187 PF02638.10 KFX87569.1 - 0.0023 16.8 0.1 0.31 9.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase like GH101 zf-C2H2 PF00096.21 KFX87570.1 - 0.00076 19.6 2.8 0.022 15.0 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX87570.1 - 0.0013 18.8 1.6 0.057 13.7 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX87570.1 - 0.15 12.2 1.8 8.6 6.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fcf1 PF04900.7 KFX87575.1 - 4.6e-12 45.9 0.0 8.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Fcf1 PP2C_2 PF13672.1 KFX87575.1 - 0.00015 21.2 0.1 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFX87575.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KFX87575.1 - 0.00018 21.0 0.0 0.043 13.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Transposase_24 PF03004.9 KFX87575.1 - 0.099 12.5 0.1 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Ribosomal_L35p PF01632.14 KFX87582.1 - 0.026 14.3 1.8 0.043 13.6 1.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L35 FA_hydroxylase PF04116.8 KFX87584.1 - 2.2e-16 60.2 18.4 2.2e-16 60.2 12.7 2.3 2 1 0 3 3 3 1 Fatty acid hydroxylase superfamily IMPDH PF00478.20 KFX87587.1 - 8.7e-130 432.6 5.1 1.1e-129 432.3 3.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KFX87587.1 - 2.9e-16 58.9 0.0 5.4e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KFX87587.1 - 3.9e-08 32.8 9.6 0.00027 20.1 0.0 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 KFX87587.1 - 2e-06 26.9 0.8 1e-05 24.5 0.3 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KFX87587.1 - 0.022 14.0 1.7 0.8 8.9 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KFX87587.1 - 0.034 13.1 0.2 0.066 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase AraC_N PF06719.8 KFX87591.1 - 0.11 11.7 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus DUF605 PF04652.11 KFX87591.1 - 0.96 8.7 8.1 1.3 8.3 5.6 1.2 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 KFX87592.1 - 1.6e-27 94.3 6.4 8e-07 28.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Myosin_TH1 PF06017.8 KFX87592.1 - 0.19 10.9 0.1 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Myosin tail Y_phosphatase2 PF03162.8 KFX87593.1 - 3.6e-47 159.7 0.0 4.9e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFX87593.1 - 3e-10 40.5 0.0 3.7e-09 37.0 0.0 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFX87593.1 - 0.005 16.1 0.1 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFX87593.1 - 0.015 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2416 PF10315.4 KFX87594.1 - 1.6e-05 25.0 0.2 1.9e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) HupE_UreJ PF04955.7 KFX87594.1 - 0.099 11.9 1.4 0.14 11.4 0.9 1.2 1 0 0 1 1 1 0 HupE / UreJ protein DUF1977 PF09320.6 KFX87595.1 - 6e-24 84.3 0.1 9.7e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFX87595.1 - 1e-20 73.2 0.5 2e-20 72.2 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Ufd2P_core PF10408.4 KFX87596.1 - 1.1e-189 631.6 12.0 1.4e-189 631.4 8.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KFX87596.1 - 8.7e-21 73.6 0.8 2.7e-20 72.0 0.5 2.0 1 0 0 1 1 1 1 U-box domain Syntaxin_2 PF14523.1 KFX87597.1 - 2.2e-27 95.0 3.1 2.2e-27 95.0 2.1 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KFX87597.1 - 1.5e-18 66.2 1.6 4.2e-18 64.7 1.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KFX87597.1 - 1.3e-05 25.2 0.8 1.3e-05 25.2 0.6 2.6 1 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 KFX87597.1 - 0.00068 19.1 0.2 0.019 14.5 0.1 2.6 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 KFX87597.1 - 0.0029 17.2 6.0 0.098 12.1 0.6 2.1 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain ISG65-75 PF11727.3 KFX87597.1 - 0.017 14.1 0.9 0.017 14.1 0.6 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF651 PF04895.7 KFX87597.1 - 0.02 14.4 0.7 0.064 12.8 0.1 2.1 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) DUF883 PF05957.8 KFX87597.1 - 0.039 14.3 11.6 0.78 10.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) EspB PF05802.6 KFX87597.1 - 0.04 12.8 0.2 0.04 12.8 0.1 1.7 2 0 0 2 2 2 0 Enterobacterial EspB protein K_channel_TID PF07941.6 KFX87597.1 - 0.09 13.0 1.7 0.18 12.0 1.2 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain AAA_13 PF13166.1 KFX87597.1 - 0.4 9.0 7.8 0.77 8.1 5.4 1.4 1 1 0 1 1 1 0 AAA domain DUF1690 PF07956.6 KFX87597.1 - 5.3 7.0 7.8 0.52 10.2 2.0 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Ndc1_Nup PF09531.5 KFX87598.1 - 4.8e-147 490.9 0.0 5.5e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DSPc PF00782.15 KFX87599.1 - 8.7e-25 86.8 0.0 1.2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KFX87599.1 - 0.00019 20.4 0.0 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Mu-like_Com PF10122.4 KFX87599.1 - 0.026 13.5 0.4 0.063 12.3 0.3 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Y_phosphatase3 PF13350.1 KFX87599.1 - 0.037 14.2 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFX87599.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Gly_transf_sug PF04488.10 KFX87602.1 - 1.3e-08 35.1 0.0 3.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFX87602.1 - 0.012 14.1 0.1 0.019 13.4 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Pectate_lyase_3 PF12708.2 KFX87604.1 - 2.4e-64 217.5 9.1 1e-52 179.4 0.2 3.5 2 1 1 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 KFX87604.1 - 2.6e-17 62.8 0.0 6.2e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Subtilase family Proteasome PF00227.21 KFX87611.1 - 2.1e-45 154.3 0.1 2.9e-31 108.2 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFX87611.1 - 2.4e-11 42.7 0.0 5.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature APH PF01636.18 KFX87612.1 - 0.046 13.4 3.7 0.63 9.7 2.5 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family MF_alpha PF04648.7 KFX87612.1 - 0.29 11.3 9.2 3.3e+02 1.8 0.0 6.0 6 0 0 6 6 6 0 Yeast mating factor alpha hormone DNA_pol3_tau_4 PF12168.3 KFX87612.1 - 0.75 10.2 4.7 28 5.1 0.0 4.4 1 1 5 6 6 6 0 DNA polymerase III subunits tau domain IV DnaB-binding Iso_dh PF00180.15 KFX87613.1 - 4.7e-84 282.2 0.0 6e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ABC_membrane PF00664.18 KFX87616.1 - 4.9e-80 268.8 26.1 3.8e-45 154.4 3.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX87616.1 - 1.4e-63 213.2 0.1 3.6e-34 117.9 0.0 3.2 2 1 0 2 2 2 2 ABC transporter Exo_endo_phos PF03372.18 KFX87616.1 - 1.4e-22 80.8 0.1 2.7e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SMC_N PF02463.14 KFX87616.1 - 7.8e-15 54.6 2.6 0.00019 20.7 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain LRR_4 PF12799.2 KFX87616.1 - 2.8e-14 52.3 5.9 4.3e-09 35.7 0.4 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA_21 PF13304.1 KFX87616.1 - 4.8e-12 46.4 0.1 0.004 17.1 0.0 4.8 3 2 1 4 4 4 3 AAA domain DUF258 PF03193.11 KFX87616.1 - 6.9e-09 35.0 0.0 0.001 18.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX87616.1 - 8.9e-09 35.5 0.3 0.0001 22.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KFX87616.1 - 1.1e-08 34.0 1.2 0.001 17.7 0.0 4.7 5 0 0 5 5 5 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KFX87616.1 - 1.8e-08 33.7 1.2 0.0024 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX87616.1 - 6.5e-08 33.4 0.0 0.011 16.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFX87616.1 - 1e-07 32.1 0.9 0.026 14.6 0.0 4.1 4 1 0 4 4 3 2 AAA domain LRR_8 PF13855.1 KFX87616.1 - 2.7e-07 30.2 2.4 4.6e-05 23.0 0.0 2.5 1 1 1 3 3 2 1 Leucine rich repeat AAA_23 PF13476.1 KFX87616.1 - 3.7e-06 27.4 0.1 0.021 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain LRR_1 PF00560.28 KFX87616.1 - 3.7e-06 26.2 4.4 0.062 13.3 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat AAA_30 PF13604.1 KFX87616.1 - 6e-06 25.9 0.7 0.062 12.8 0.1 3.6 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KFX87616.1 - 2.1e-05 24.8 0.1 0.24 11.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFX87616.1 - 8.5e-05 22.2 0.2 0.19 11.4 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_25 PF13481.1 KFX87616.1 - 0.00023 20.6 2.4 0.48 9.7 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 KFX87616.1 - 0.00039 20.3 0.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KFX87616.1 - 0.0005 19.2 0.1 0.057 12.5 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 KFX87616.1 - 0.00072 19.7 2.6 0.22 11.7 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX87616.1 - 0.00089 19.0 0.1 0.86 9.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KFX87616.1 - 0.0017 17.4 0.1 1.6 7.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.10 KFX87616.1 - 0.0022 16.7 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KFX87616.1 - 0.0024 17.3 2.1 0.55 9.6 0.1 2.8 3 0 0 3 3 2 1 AAA-like domain AAA_14 PF13173.1 KFX87616.1 - 0.0025 17.6 0.0 0.64 9.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 KFX87616.1 - 0.0032 17.3 0.7 1.9 8.4 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KFX87616.1 - 0.0039 16.8 0.1 2.9 7.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KFX87616.1 - 0.0045 16.5 0.4 1.1 8.7 0.0 2.9 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 KFX87616.1 - 0.0062 16.5 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KFX87616.1 - 0.0082 15.7 0.0 2.4 7.6 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family LRR_7 PF13504.1 KFX87616.1 - 0.015 15.4 3.1 3.8 8.1 0.1 4.0 3 0 0 3 3 3 0 Leucine rich repeat AAA_11 PF13086.1 KFX87616.1 - 0.017 14.7 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFX87616.1 - 0.029 13.2 0.4 0.84 8.4 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.12 KFX87616.1 - 0.031 13.8 0.1 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFX87616.1 - 0.034 14.1 0.0 4.7 7.1 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 KFX87616.1 - 0.037 13.8 0.8 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 KFX87616.1 - 0.039 14.1 0.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 KFX87616.1 - 0.088 12.4 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Erythro_esteras PF05139.9 KFX87617.1 - 6.4e-135 449.7 0.9 7.5e-135 449.5 0.6 1.0 1 0 0 1 1 1 1 Erythromycin esterase Flavodoxin_1 PF00258.20 KFX87617.1 - 0.086 12.8 0.0 7.8 6.4 0.0 2.8 2 1 0 2 2 2 0 Flavodoxin FAD_binding_4 PF01565.18 KFX87618.1 - 1.3e-17 63.5 0.1 2.1e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ArsB PF02040.10 KFX87619.1 - 1.9e-13 50.1 22.1 2.2e-08 33.4 6.0 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein ADH_zinc_N PF00107.21 KFX87621.1 - 3.5e-22 78.3 0.0 6.4e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX87621.1 - 1.5e-12 48.4 0.0 3.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX87621.1 - 0.00016 21.4 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KFX87621.1 - 0.0087 15.6 0.1 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KFX87621.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GFO_IDH_MocA PF01408.17 KFX87622.1 - 3.2e-18 66.3 1.1 5.4e-18 65.6 0.8 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GARS_N PF02844.10 KFX87622.1 - 0.0009 19.6 0.1 0.0025 18.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain Semialdhyde_dh PF01118.19 KFX87622.1 - 0.0033 17.7 0.2 0.0062 16.8 0.2 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 KFX87622.1 - 0.032 14.7 0.8 0.076 13.5 0.2 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase CoA_binding_2 PF13380.1 KFX87622.1 - 0.13 12.4 1.9 0.31 11.2 1.3 1.7 1 1 0 1 1 1 0 CoA binding domain NAD_binding_3 PF03447.11 KFX87622.1 - 0.15 12.4 1.0 0.28 11.5 0.7 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 KFX87624.1 - 3.1e-78 262.7 0.0 5.3e-78 262.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX87624.1 - 1.6e-45 155.8 0.1 2.9e-45 154.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFX87624.1 - 5.7e-31 106.8 0.2 1.3e-30 105.6 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFX87624.1 - 1.3e-22 79.9 0.0 2.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KFX87624.1 - 4.5e-19 68.4 12.6 4.9e-10 39.5 1.2 2.9 3 0 0 3 3 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KFX87624.1 - 7.1e-11 41.7 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 KFX87624.1 - 8.9e-06 24.8 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.20 KFX87624.1 - 7.7e-05 22.6 0.0 0.00046 20.1 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Abhydrolase_5 PF12695.2 KFX87624.1 - 0.00022 20.9 0.0 0.0034 17.1 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family RmlD_sub_bind PF04321.12 KFX87624.1 - 0.00025 20.0 0.0 0.019 13.8 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KFX87624.1 - 0.0022 16.9 0.0 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KFX87624.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SnoaL_4 PF13577.1 KFX87625.1 - 8.2e-23 80.6 0.1 9.3e-23 80.5 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KFX87625.1 - 2.3e-07 31.3 0.3 3.2e-07 30.9 0.2 1.3 1 1 0 1 1 1 1 Putative lumazine-binding SnoaL_2 PF12680.2 KFX87625.1 - 0.0055 17.0 0.0 0.0072 16.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFX87625.1 - 0.0057 16.8 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF792 PF05632.6 KFX87625.1 - 0.1 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) ADH_N PF08240.7 KFX87626.1 - 4.2e-12 45.7 0.0 3.8e-11 42.7 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX87626.1 - 4.9e-07 29.3 0.2 8e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_2 PF00891.13 KFX87627.1 - 8.7e-14 51.2 1.8 4.9e-13 48.8 0.2 2.6 2 1 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 KFX87627.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2732 PF10809.3 KFX87627.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Transferase PF02458.10 KFX87628.1 - 8.4e-05 21.1 0.0 0.00048 18.7 0.0 1.9 1 1 0 1 1 1 1 Transferase family DUF2064 PF09837.4 KFX87628.1 - 0.072 12.7 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_hydro_3 PF00933.16 KFX87629.1 - 1e-42 146.1 0.0 1.2e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1343 PF07075.6 KFX87630.1 - 3.5e-126 420.9 0.0 4e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) MFS_1 PF07690.11 KFX87631.1 - 1.6e-31 109.3 25.7 1.6e-31 109.3 17.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0075 PF03702.9 KFX87632.1 - 3.5e-75 253.1 0.0 4.2e-75 252.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Trypan_PARP PF05887.6 KFX87639.1 - 9.1 6.0 7.7 17 5.1 5.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DivIC PF04977.10 KFX87640.1 - 0.11 11.9 5.5 5.7 6.4 0.1 2.8 2 1 0 2 2 2 0 Septum formation initiator Mnd1 PF03962.10 KFX87640.1 - 0.27 10.9 14.6 0.08 12.6 1.8 2.4 2 0 0 2 2 2 0 Mnd1 family GAS PF13851.1 KFX87640.1 - 2.2 7.4 16.7 0.79 8.8 2.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding 4HBT_2 PF13279.1 KFX87641.1 - 1.3e-20 74.0 0.0 2.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KFX87641.1 - 0.048 13.7 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KFX87641.1 - 0.1 11.5 0.1 3 6.7 0.0 2.3 2 0 0 2 2 2 0 Acyl-ACP thioesterase Complex1_LYR_2 PF13233.1 KFX87642.1 - 2.6e-08 34.2 0.0 3.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX87642.1 - 0.00083 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX87642.1 - 0.0015 18.7 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_11 PF08241.7 KFX87643.1 - 7.6e-12 45.5 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX87643.1 - 7.7e-12 45.4 0.0 1.8e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87643.1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX87643.1 - 8.1e-09 36.0 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX87643.1 - 6.1e-08 32.7 0.0 2.6e-07 30.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX87643.1 - 3e-07 30.3 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX87643.1 - 5.8e-06 26.6 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX87643.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 KFX87643.1 - 0.00025 20.7 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX87643.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KFX87643.1 - 0.002 18.9 0.0 0.0058 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX87643.1 - 0.0054 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KFX87643.1 - 0.0059 16.1 0.0 0.023 14.2 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RE_MjaI PF09568.5 KFX87643.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 MjaI restriction endonuclease Methyltransf_8 PF05148.10 KFX87643.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase VHS PF00790.14 KFX87650.1 - 6e-24 84.2 0.0 1.5e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KFX87650.1 - 5.8e-10 39.0 1.3 1.3e-09 37.9 0.9 1.6 1 0 0 1 1 1 1 GAT domain DUF3275 PF11679.3 KFX87650.1 - 4.3 6.9 6.2 0.81 9.2 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) ARID PF01388.16 KFX87651.1 - 1.4e-16 60.0 0.0 1e-09 38.1 0.0 2.6 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain Myb_DNA-bind_2 PF08914.6 KFX87651.1 - 5.3e-16 58.1 0.2 2.1e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.3 KFX87651.1 - 1.8e-14 53.3 0.4 4.2e-14 52.1 0.3 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 KFX87651.1 - 4.4e-05 23.9 2.7 0.0002 21.8 0.1 3.2 3 0 0 3 3 3 1 Rap1, DNA-binding zf-DHHC PF01529.15 KFX87652.1 - 9.6e-32 109.7 3.0 9.6e-32 109.7 2.1 2.0 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF1418 PF07214.7 KFX87652.1 - 0.0068 16.0 1.1 0.017 14.7 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) Flavoprotein PF02441.14 KFX87653.1 - 8.2e-16 57.8 0.0 2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Flavoprotein DUF21 PF01595.15 KFX87654.1 - 9.8e-26 90.1 0.3 2.9e-25 88.6 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFX87654.1 - 5.6e-08 32.4 0.1 0.0045 16.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF2434 PF10361.4 KFX87654.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Chromo PF00385.19 KFX87656.1 - 1.3e-10 40.7 0.2 1.3e-10 40.7 0.1 2.4 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KFX87656.1 - 7.4e-07 28.9 0.0 3.9e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Chromo shadow domain DUF3022 PF11226.3 KFX87656.1 - 0.03 14.1 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) Ribosomal_L35Ae PF01247.13 KFX87656.1 - 0.058 13.1 0.1 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L35Ae Thioredoxin_8 PF13905.1 KFX87656.1 - 0.084 13.0 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Myc_N PF01056.13 KFX87656.1 - 1.2 8.2 8.8 1.9 7.5 4.2 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Pep_M12B_propep PF01562.14 KFX87658.1 - 0.11 12.3 0.2 0.31 10.8 0.0 1.6 1 1 1 2 2 2 0 Reprolysin family propeptide Pkinase PF00069.20 KFX87662.1 - 2.9e-70 236.3 0.0 4.7e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87662.1 - 2e-44 151.6 0.0 3.5e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFX87662.1 - 2.7e-20 72.5 0.0 2.7e-20 72.5 0.0 3.1 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 KFX87662.1 - 3.2e-07 29.5 0.0 5.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX87662.1 - 0.048 13.3 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.24 KFX87667.1 - 1.3e-28 99.6 0.1 6e-28 97.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX87667.1 - 1.8e-23 82.1 0.1 3.4e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFX87667.1 - 0.017 14.9 0.3 0.055 13.2 0.0 2.1 2 1 0 2 2 2 0 Part of AAA domain Anp1 PF03452.9 KFX87670.1 - 2.5e-107 358.0 0.0 3.1e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KFX87670.1 - 0.035 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 FixQ PF05545.6 KFX87670.1 - 0.098 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Band_7 PF01145.20 KFX87673.1 - 3.7e-26 92.1 3.6 6.2e-26 91.3 2.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family UcrQ PF02939.11 KFX87674.1 - 4.7e-31 106.4 0.3 5.7e-31 106.1 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Nucleopor_Nup85 PF07575.8 KFX87675.1 - 5.9e-14 51.1 3.4 1.6e-06 26.6 1.3 3.9 2 1 0 2 2 2 2 Nup85 Nucleoporin DUF2282 PF10048.4 KFX87679.1 - 0.7 9.8 8.4 2.4 8.1 1.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2282) Ctr PF04145.10 KFX87680.1 - 1.8e-32 112.3 0.1 2.1e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Malate_synthase PF01274.17 KFX87681.1 - 3.7e-233 774.2 0.0 4.2e-233 774.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Rpr2 PF04032.11 KFX87682.1 - 2.2e-23 81.9 0.4 5.1e-23 80.7 0.2 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_3 PF13878.1 KFX87682.1 - 2.3 7.8 5.1 3.6 7.2 0.2 2.7 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DEAD PF00270.24 KFX87683.1 - 9.8e-37 126.0 0.2 1.6e-36 125.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX87683.1 - 1.2e-24 85.9 0.0 8.7e-23 79.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX87683.1 - 1.1e-07 31.9 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UDG PF03167.14 KFX87694.1 - 1.4e-07 31.0 0.0 5.7e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily MARVEL PF01284.18 KFX87694.1 - 0.00086 19.1 10.3 0.0042 16.9 7.2 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF2189 PF09955.4 KFX87694.1 - 0.043 13.7 8.1 3.5 7.5 2.1 3.7 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2189) CytB6-F_Fe-S PF08802.5 KFX87694.1 - 0.05 13.5 0.6 0.17 11.8 0.4 1.9 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Isochorismatase PF00857.15 KFX87695.1 - 4e-29 101.7 0.0 9.4e-29 100.5 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family WD40 PF00400.27 KFX87696.1 - 5.5e-06 26.0 1.3 0.18 11.7 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat UDG PF03167.14 KFX87697.1 - 1.6e-10 40.6 0.0 2.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MRI PF15325.1 KFX87697.1 - 0.032 15.1 0.0 0.063 14.2 0.0 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Nup188 PF10487.4 KFX87698.1 - 1.1e-43 149.3 0.0 5.4e-43 147.0 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF1754 PF08555.5 KFX87698.1 - 4.4e-12 46.4 10.0 9.7e-12 45.3 6.9 1.6 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) IGPS PF00218.16 KFX87699.1 - 1.5e-93 312.5 0.0 2.5e-93 311.8 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KFX87699.1 - 6.1e-54 182.5 0.6 2.8e-51 173.9 0.1 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KFX87699.1 - 2.6e-51 173.8 0.0 4.5e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFX87699.1 - 6.7e-05 22.4 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KFX87699.1 - 0.0058 16.1 1.1 0.16 11.4 0.1 2.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KFX87699.1 - 0.02 14.1 0.1 0.066 12.4 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KFX87699.1 - 0.046 12.6 0.1 0.27 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase BRCT PF00533.21 KFX87700.1 - 4.7e-10 39.4 0.0 8.1e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nop16 PF09420.5 KFX87700.1 - 0.0049 16.9 0.1 0.0091 16.1 0.0 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein Nop16 MOSC PF03473.12 KFX87700.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 MOSC domain IPK PF03770.11 KFX87704.1 - 6.4e-54 182.6 0.0 7.8e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 KFX87705.1 - 3.8e-120 401.3 0.0 4.5e-120 401.1 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 NAGidase PF07555.8 KFX87706.1 - 6.4e-100 334.0 0.2 1.1e-99 333.2 0.1 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 KFX87706.1 - 5.6e-19 68.8 0.1 1.1e-18 67.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.9 KFX87706.1 - 4.5e-05 23.4 0.1 0.00013 21.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus TPR_12 PF13424.1 KFX87707.1 - 3.5e-24 84.5 8.4 8.5e-09 35.2 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 KFX87707.1 - 2.2e-17 62.8 0.0 5.2e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 KFX87707.1 - 5.8e-16 57.8 5.7 0.00074 19.3 0.1 6.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFX87707.1 - 1.2e-10 40.8 1.5 2e-06 27.3 0.1 5.5 6 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 KFX87707.1 - 8.8e-09 34.6 7.8 0.075 12.9 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX87707.1 - 5.6e-07 29.6 6.5 0.65 10.7 0.2 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX87707.1 - 9.4e-07 28.1 0.7 0.0011 18.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX87707.1 - 1e-05 25.5 0.7 0.03 14.4 0.1 3.3 3 0 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 KFX87707.1 - 7.8e-05 22.8 0.0 0.0003 20.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_7 PF13176.1 KFX87707.1 - 8e-05 22.1 4.6 0.28 11.0 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.15 KFX87707.1 - 0.00026 20.7 2.3 0.92 9.6 0.0 4.4 4 0 0 4 4 4 1 PPR repeat TPR_8 PF13181.1 KFX87707.1 - 0.0003 20.3 6.7 0.16 11.8 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX87707.1 - 0.00052 20.2 11.7 0.15 12.4 1.1 5.4 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX87707.1 - 0.027 14.6 0.1 90 3.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX87707.1 - 0.12 12.8 2.5 81 4.0 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M49 PF03571.10 KFX87709.1 - 1.5e-195 650.4 0.0 1.8e-195 650.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 APH PF01636.18 KFX87710.1 - 0.0019 17.9 0.8 0.011 15.4 0.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Beta-lactamase PF00144.19 KFX87711.1 - 7.7e-31 107.3 0.9 1.9e-30 106.0 0.6 1.5 1 1 0 1 1 1 1 Beta-lactamase Melibiase PF02065.13 KFX87712.1 - 1.3e-21 76.7 0.6 1.1e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Melibiase CBM_1 PF00734.13 KFX87712.1 - 6.7e-12 44.8 14.5 6.7e-12 44.8 10.1 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_30 PF02055.11 KFX87713.1 - 5.2e-05 21.6 0.2 0.0059 14.8 0.0 2.4 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KFX87713.1 - 0.008 15.1 0.0 0.041 12.8 0.0 2.0 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 ArabFuran-catal PF09206.6 KFX87714.1 - 4.3e-155 515.5 22.2 5.5e-155 515.1 15.4 1.1 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic CBM_1 PF00734.13 KFX87714.1 - 8e-11 41.4 17.5 8e-11 41.4 12.1 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_39 PF01229.12 KFX87715.1 - 0.001 17.5 0.1 0.0014 17.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 CBM_1 PF00734.13 KFX87715.1 - 0.085 12.5 15.5 0.24 11.1 10.8 1.8 1 0 0 1 1 1 0 Fungal cellulose binding domain DUF2794 PF10984.3 KFX87715.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) Sulfatase PF00884.18 KFX87716.1 - 2.5e-45 155.0 1.1 1.6e-43 149.0 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KFX87716.1 - 0.0012 18.2 1.0 0.024 13.9 0.0 2.5 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFX87716.1 - 0.0064 14.9 0.0 0.0087 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KFX87716.1 - 0.018 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sulfatase_C PF14707.1 KFX87716.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Thioredox_DsbH PF03190.10 KFX87716.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 MFS_1 PF07690.11 KFX87717.1 - 2.1e-19 69.4 20.3 2.6e-19 69.1 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 KFX87717.1 - 0.024 14.4 0.2 0.056 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) MatE PF01554.13 KFX87718.1 - 1.1e-53 181.2 27.9 4.6e-27 94.6 6.7 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KFX87718.1 - 4.7e-05 23.2 4.1 4.7e-05 23.2 2.9 3.9 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF202 PF02656.10 KFX87719.1 - 2.2e-19 69.4 1.2 1.1e-18 67.2 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Fibrillarin_2 PF10113.4 KFX87719.1 - 0.028 12.7 0.0 0.036 12.4 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein 2TM PF13239.1 KFX87719.1 - 0.029 14.4 0.8 0.061 13.3 0.1 1.9 1 1 1 2 2 2 0 2TM domain COX4_pro_2 PF07835.7 KFX87719.1 - 0.035 14.0 1.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF1408 PF07193.6 KFX87720.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Autophagy_N PF03986.8 KFX87721.1 - 8.5e-21 74.2 1.3 1.1e-20 73.9 0.1 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KFX87721.1 - 1.6e-19 69.7 0.0 2.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KFX87721.1 - 4.4e-13 48.0 0.3 7.1e-13 47.4 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PAH PF02671.16 KFX87722.1 - 1.8e-08 33.8 1.7 0.00073 19.1 0.1 3.6 3 1 0 3 3 3 3 Paired amphipathic helix repeat Pec_lyase_C PF00544.14 KFX87724.1 - 2.6e-45 154.3 0.9 4.8e-45 153.5 0.6 1.4 1 0 0 1 1 1 1 Pectate lyase Sulfotransfer_3 PF13469.1 KFX87725.1 - 9.1e-08 33.1 0.1 2.1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase family DUF4298 PF14131.1 KFX87726.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) NmrA PF05368.8 KFX87733.1 - 3.2e-59 200.0 0.3 4e-59 199.6 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX87733.1 - 2.9e-16 60.0 0.8 4.5e-16 59.3 0.4 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX87733.1 - 1.8e-07 30.1 0.2 2.6e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PUL PF08324.6 KFX87734.1 - 2.1e-44 151.3 0.0 2.9e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KFX87734.1 - 2.1e-42 143.8 0.2 6.5e-42 142.2 0.4 1.7 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KFX87734.1 - 1.5e-41 138.7 7.7 6.8e-07 28.9 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat WD40 PF00400.27 KFX87735.1 - 9e-43 142.6 5.1 1.1e-11 44.1 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFX87735.1 - 0.023 13.4 0.0 5 5.7 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 KFX87735.1 - 0.068 11.2 0.5 0.53 8.3 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Fe-S_biosyn PF01521.15 KFX87742.1 - 9.3e-20 70.6 0.0 1.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1365 PF07103.6 KFX87752.1 - 2.6e-21 75.8 0.0 4.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CP12 PF02672.10 KFX87753.1 - 0.095 13.1 2.0 0.17 12.3 1.4 1.5 1 1 0 1 1 1 0 CP12 domain Dsh_C PF12316.3 KFX87753.1 - 0.46 10.5 6.3 0.54 10.3 4.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Menin PF05053.8 KFX87753.1 - 7.2 4.6 6.7 8 4.4 4.6 1.0 1 0 0 1 1 1 0 Menin DUF2066 PF09839.4 KFX87755.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Pyr_redox_3 PF13738.1 KFX87756.1 - 1.7e-26 93.5 0.0 4.3e-25 88.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX87756.1 - 5.5e-14 51.2 0.2 4.4e-13 48.2 0.1 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFX87756.1 - 3.6e-12 45.8 0.1 8.9e-09 34.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX87756.1 - 5.1e-10 39.2 0.0 1.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX87756.1 - 5.1e-09 36.3 0.0 4.2e-07 30.0 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX87756.1 - 1.2e-05 25.1 0.0 0.004 16.9 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KFX87756.1 - 0.00064 18.7 0.0 0.0085 15.0 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX87756.1 - 0.041 12.7 0.0 0.86 8.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KFX87756.1 - 0.067 13.5 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX87756.1 - 0.068 13.2 0.0 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KFX87756.1 - 0.078 11.8 0.0 0.45 9.3 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 KFX87756.1 - 0.13 10.6 0.0 10 4.4 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KFX87756.1 - 0.25 10.1 0.0 9.4 4.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FSH1 PF03959.8 KFX87757.1 - 2.1e-54 184.2 0.0 2.7e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFX87757.1 - 1.8e-07 31.3 0.0 4.9e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX87757.1 - 2.2e-05 24.2 0.0 5.2e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX87757.1 - 0.0096 15.3 0.2 13 5.1 0.0 3.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 KFX87757.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.13 KFX87757.1 - 0.12 11.6 0.0 9.8 5.3 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF1572 PF07609.6 KFX87761.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) DinB PF05163.7 KFX87764.1 - 0.0017 18.0 0.5 0.0017 18.0 0.3 1.7 2 0 0 2 2 2 1 DinB family BUD22 PF09073.5 KFX87765.1 - 0.12 11.4 27.9 0.14 11.1 19.3 1.0 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 KFX87765.1 - 0.73 8.2 28.4 0.85 8.0 19.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF4220 PF13968.1 KFX87765.1 - 1.3 8.0 2.9 1.3 8.0 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Prothymosin PF03247.9 KFX87765.1 - 3.2 7.9 45.3 0.16 12.1 25.5 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Nop14 PF04147.7 KFX87765.1 - 7.6 4.3 33.3 9.9 3.9 23.1 1.2 1 0 0 1 1 1 0 Nop14-like family TctA PF01970.11 KFX87771.1 - 0.06 11.7 0.9 0.09 11.1 0.7 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Peptidase_S49_N PF08496.5 KFX87771.1 - 3.3 7.4 16.1 2.1 8.0 6.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RNA_pol_Rpc4 PF05132.9 KFX87771.1 - 4.8 7.1 6.5 8.7 6.3 2.2 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 RRM_1 PF00076.17 KFX87772.1 - 6.7e-09 35.2 0.1 1.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX87772.1 - 2.2e-06 27.5 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX87772.1 - 0.033 14.0 0.5 0.11 12.3 0.4 1.9 1 1 0 1 1 1 0 RNA binding motif DUF3510 PF12022.3 KFX87772.1 - 0.077 13.0 1.4 2.6 8.1 1.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) Nup35_RRM_2 PF14605.1 KFX87772.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sec62 PF03839.11 KFX87773.1 - 0.82 9.0 3.0 0.91 8.8 2.1 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 O-FucT PF10250.4 KFX87776.1 - 8.7e-06 25.0 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Dicty_CAR PF05462.6 KFX87777.1 - 2e-16 59.7 5.8 2e-16 59.7 4.0 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KFX87777.1 - 7.2e-08 31.8 6.1 7.2e-08 31.8 4.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 KFX87777.1 - 9.8e-08 31.8 11.5 1.9e-07 30.8 8.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KFX87777.1 - 7e-05 22.1 4.7 0.00012 21.2 3.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SAM_1 PF00536.25 KFX87780.1 - 5.2e-10 39.3 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX87780.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KFX87780.1 - 0.0048 16.6 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pec_lyase_C PF00544.14 KFX87794.1 - 2.7e-43 147.7 10.0 3.9e-43 147.2 6.9 1.2 1 0 0 1 1 1 1 Pectate lyase GST_N_3 PF13417.1 KFX87795.1 - 3.6e-11 43.1 0.1 5.8e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX87795.1 - 6.9e-08 32.3 0.1 1.5e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX87795.1 - 5.3e-07 29.5 0.0 8.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX87795.1 - 0.00021 21.1 0.1 0.00039 20.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFX87795.1 - 0.00094 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX87795.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hce2 PF14856.1 KFX87796.1 - 2.4e-16 59.4 0.0 3.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor zf-C2H2_4 PF13894.1 KFX87799.1 - 0.0036 17.5 6.1 0.23 11.8 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX87799.1 - 0.012 15.9 9.6 0.098 13.0 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type AMP-binding PF00501.23 KFX87802.1 - 4.1e-29 101.2 0.0 4.9e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Hemerythrin PF01814.18 KFX87803.1 - 1.5e-06 28.4 0.1 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DeoC PF01791.4 KFX87804.1 - 3e-42 144.5 2.2 3.8e-42 144.2 1.5 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 KFX87804.1 - 0.021 14.1 0.2 0.039 13.2 0.1 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein Ank_2 PF12796.2 KFX87806.1 - 3.5e-46 155.4 0.0 1.2e-11 44.7 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX87806.1 - 1.1e-36 122.8 6.7 0.00012 21.7 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KFX87806.1 - 1.5e-33 114.5 0.1 1.4e-06 28.6 0.0 6.4 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX87806.1 - 9.8e-27 92.3 10.1 3.7e-07 30.1 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX87806.1 - 1.6e-22 77.3 0.0 0.0026 17.8 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat NIL PF09383.5 KFX87806.1 - 2.5e-07 30.1 0.0 16 5.1 0.0 7.4 8 0 0 8 8 8 0 NIL domain DUF676 PF05057.9 KFX87806.1 - 4.4e-05 22.8 0.0 8.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFX87806.1 - 8.2e-05 22.2 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFX87806.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX87806.1 - 0.00058 19.6 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KFX87806.1 - 0.00085 19.4 0.1 0.0059 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX87806.1 - 0.0064 16.4 1.2 0.037 14.0 0.9 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF829 PF05705.9 KFX87806.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) TipAS PF07739.8 KFX87806.1 - 0.15 12.4 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain RabGAP-TBC PF00566.13 KFX87807.1 - 6e-46 156.6 0.0 1e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KFX87807.1 - 1.7e-05 24.8 0.1 0.0011 19.0 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain pair GRAM PF02893.15 KFX87807.1 - 0.00027 20.3 0.0 0.0007 19.0 0.0 1.8 1 1 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 KFX87807.1 - 0.00035 20.2 3.0 0.0095 15.7 0.2 3.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.27 KFX87807.1 - 0.0032 16.6 0.4 0.097 12.0 0.3 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 KFX87807.1 - 0.025 13.9 2.9 0.057 12.7 0.6 2.7 3 0 0 3 3 3 0 EF hand DUF3441 PF11923.3 KFX87808.1 - 2.5e-35 120.4 0.2 2.5e-35 120.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KFX87808.1 - 2.1e-30 105.6 4.8 2.1e-30 105.6 3.3 3.8 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KFX87808.1 - 3.2e-21 74.9 0.0 7.4e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) zf-C3H1 PF10650.4 KFX87808.1 - 2.8e-13 49.0 1.3 4.6e-13 48.3 0.9 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.16 KFX87809.1 - 2.4e-251 835.6 0.0 2.4e-251 835.6 0.0 2.5 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFX87809.1 - 5.8e-29 100.4 262.8 5.8e-26 90.5 73.3 6.8 2 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 KFX87809.1 - 2.6e-06 27.0 0.0 6.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KFX87809.1 - 0.082 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain CTP_synth_N PF06418.9 KFX87810.1 - 5.9e-111 369.9 0.2 9e-111 369.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFX87810.1 - 3.3e-53 180.0 0.0 5e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFX87810.1 - 1.4e-06 27.8 0.1 6.7e-06 25.7 0.0 2.1 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 KFX87810.1 - 0.002 17.5 0.0 0.0044 16.4 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KFX87810.1 - 0.08 11.9 0.9 0.14 11.1 0.6 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase F-box PF00646.28 KFX87811.1 - 2.9e-05 23.5 0.6 9.4e-05 21.9 0.1 2.0 2 0 0 2 2 2 1 F-box domain DUF1802 PF08819.6 KFX87811.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) F-box-like PF12937.2 KFX87813.1 - 0.002 17.8 0.1 0.0047 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX87813.1 - 0.013 15.1 0.5 0.024 14.2 0.0 1.7 2 0 0 2 2 2 0 F-box domain AA_permease PF00324.16 KFX87814.1 - 1.5e-125 419.2 42.5 1.7e-125 419.0 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX87814.1 - 3.4e-40 137.8 52.5 4e-40 137.6 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 KFX87814.1 - 0.0053 16.8 1.8 0.0053 16.8 1.2 4.7 5 0 0 5 5 5 1 PrgI family protein DUF3593 PF12159.3 KFX87814.1 - 0.025 14.3 0.2 1.5 8.6 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) ABC1 PF03109.11 KFX87815.1 - 3.1e-22 78.7 0.0 7.2e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KFX87815.1 - 0.014 15.1 1.2 0.044 13.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2457 PF10446.4 KFX87817.1 - 8.4e-105 351.1 45.3 8.4e-105 351.1 31.4 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 KFX87817.1 - 0.22 9.3 40.5 0.026 12.4 20.5 2.3 2 0 0 2 2 2 0 Nop14-like family Alpha_GJ PF03229.8 KFX87823.1 - 0.0027 18.0 0.8 0.01 16.1 0.1 2.0 2 0 0 2 2 2 1 Alphavirus glycoprotein J RgpF PF05045.7 KFX87824.1 - 0.0046 15.5 0.1 0.06 11.8 0.0 2.0 2 0 0 2 2 2 2 Rhamnan synthesis protein F RNA_pol_I_A49 PF06870.7 KFX87825.1 - 4.4e-77 259.2 0.6 5.9e-77 258.8 0.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HDOD PF08668.7 KFX87825.1 - 0.025 13.8 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 HDOD domain Ribosomal_L41 PF05162.8 KFX87826.1 - 2.3e-07 30.3 26.4 3.7e-07 29.6 18.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 Pkinase PF00069.20 KFX87827.1 - 3.4e-61 206.6 0.0 6.2e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87827.1 - 1.9e-27 95.9 0.0 4.7e-27 94.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFX87827.1 - 2.5e-09 37.1 0.0 5.8e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFX87827.1 - 2.5e-05 23.4 0.0 6.7e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFX87827.1 - 0.0014 17.7 0.0 0.0031 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFX87827.1 - 0.014 14.7 0.1 0.059 12.7 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL WSC PF01822.14 KFX87830.1 - 1.5e-11 44.0 9.0 1.5e-11 44.0 6.2 1.8 2 0 0 2 2 2 1 WSC domain Glyco_hydro_18 PF00704.23 KFX87833.1 - 2e-47 162.3 0.0 2.5e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3245 PF11595.3 KFX87840.1 - 3.6e-12 46.7 6.9 3.6e-12 46.7 4.8 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3245) MCPVI PF02993.9 KFX87840.1 - 6.3 6.8 12.7 9.5 6.2 8.8 1.4 1 0 0 1 1 1 0 Minor capsid protein VI ATP-grasp_2 PF08442.5 KFX87841.1 - 1.7e-79 265.9 0.7 2.7e-79 265.2 0.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KFX87841.1 - 1e-26 93.3 0.3 2.9e-26 91.9 0.2 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFX87841.1 - 1.1e-09 37.9 0.3 2.2e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KFX87841.1 - 0.00097 18.7 0.9 0.017 14.6 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KFX87841.1 - 0.0043 16.8 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ribosomal_S11 PF00411.14 KFX87841.1 - 0.031 14.4 0.2 1.9 8.6 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S11 Acetyltransf_1 PF00583.19 KFX87843.1 - 3.6e-06 26.9 0.0 6.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 KFX87843.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 KFX87843.1 - 2.1e-05 24.5 0.0 0.0001 22.3 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KFX87843.1 - 0.015 15.8 0.0 0.11 13.1 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX87843.1 - 0.035 14.2 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.15 KFX87844.1 - 4.8e-60 203.1 2.1 5.1e-58 196.4 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein Peptidase_M22 PF00814.20 KFX87844.1 - 0.02 14.3 0.3 0.086 12.3 0.1 2.2 3 0 0 3 3 3 0 Glycoprotease family Prefoldin_2 PF01920.15 KFX87845.1 - 8.4e-25 86.5 4.3 1.5e-24 85.7 3.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 KFX87845.1 - 0.0034 16.8 1.7 0.0041 16.5 1.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SspP PF08179.7 KFX87845.1 - 0.1 12.8 0.4 0.23 11.7 0.2 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein P family Spc24 PF08286.6 KFX87845.1 - 1.9 8.1 7.3 5.9 6.6 2.3 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 KFX87845.1 - 2.2 8.2 5.0 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2951 PF11166.3 KFX87845.1 - 7.6 6.4 7.6 60 3.5 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) APC10 PF03256.11 KFX87846.1 - 1.1e-49 168.6 0.0 1.6e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 KFX87846.1 - 0.65 8.4 7.4 0.85 8.0 5.1 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KFX87847.1 - 9.4e-96 320.8 30.1 9.4e-96 320.8 20.9 2.4 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 KFX87847.1 - 5.9e-20 71.3 0.0 1.6e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain ACCA PF03255.9 KFX87847.1 - 0.037 13.5 3.0 0.04 13.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spt20 PF12090.3 KFX87848.1 - 1.1e-43 148.7 0.0 1.1e-43 148.7 0.0 5.3 3 2 1 4 4 4 1 Spt20 family Hexapep PF00132.19 KFX87850.1 - 9.8e-08 31.1 2.7 0.0071 15.8 0.3 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFX87850.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 KFX87850.1 - 0.005 15.4 1.3 1.6 7.1 0.1 2.2 1 1 1 2 2 2 2 L-fucokinase NTP_transferase PF00483.18 KFX87850.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Band_7 PF01145.20 KFX87851.1 - 5.5e-14 52.4 0.1 5.5e-14 52.4 0.0 2.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFX87851.1 - 0.029 13.8 0.1 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Peptidase_M28 PF04389.12 KFX87863.1 - 2.6e-28 98.9 0.1 5.8e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFX87863.1 - 2.1e-07 30.6 0.1 4e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1774 PF08611.5 KFX87865.1 - 4.5e-31 106.8 1.6 4.5e-31 106.8 1.1 2.7 2 1 2 4 4 4 1 Fungal protein of unknown function (DUF1774) FixQ PF05545.6 KFX87865.1 - 0.09 12.4 0.5 0.09 12.4 0.3 3.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Herpes_UL36 PF03586.8 KFX87865.1 - 0.48 9.4 2.2 5.7 5.9 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein Pex24p PF06398.6 KFX87867.1 - 8.2e-32 110.3 0.0 1.1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 KFX87867.1 - 0.014 13.2 0.0 0.016 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Pkinase PF00069.20 KFX87868.1 - 6.4e-56 189.3 0.0 1.1e-55 188.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87868.1 - 2.2e-18 66.2 0.1 7.1e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX87868.1 - 0.13 12.0 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX87868.1 - 0.13 11.8 0.2 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_1 PF00175.16 KFX87868.1 - 0.15 12.6 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain NAM-associated PF14303.1 KFX87868.1 - 0.16 12.2 4.2 0.83 9.9 2.9 2.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Catalase PF00199.14 KFX87870.1 - 3.3e-42 144.5 0.0 3.6e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Cu-oxidase_3 PF07732.10 KFX87871.1 - 1.4e-47 160.2 0.2 1.4e-47 160.2 0.1 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 KFX87871.1 - 5.2e-39 133.6 1.2 8.8e-38 129.7 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX87871.1 - 2.3e-38 130.8 7.6 2.4e-33 114.5 1.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase FtsX PF02687.16 KFX87871.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsX-like permease family Phosphoesterase PF04185.9 KFX87872.1 - 6.7e-34 117.7 4.5 1.3e-33 116.7 3.1 1.4 1 1 0 1 1 1 1 Phosphoesterase family RRM_1 PF00076.17 KFX87876.1 - 2.4e-26 91.1 0.0 6.4e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX87876.1 - 2e-13 50.0 0.0 1.4e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX87876.1 - 0.0017 18.1 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 KFX87877.1 - 6.8e-20 71.2 0.0 1.6e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 KFX87877.1 - 0.0017 18.1 0.1 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX87877.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3656 PF12392.3 KFX87877.1 - 0.087 12.8 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Collagenase NOA36 PF06524.7 KFX87877.1 - 0.093 11.9 1.7 0.11 11.7 1.2 1.1 1 0 0 1 1 1 0 NOA36 protein RNase_H2_suC PF08615.6 KFX87877.1 - 0.27 11.0 2.2 0.54 10.1 1.6 1.5 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2235 PF09994.4 KFX87883.1 - 2.7e-19 69.6 0.1 3.6e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.13 KFX87884.1 - 1.6e-17 63.2 0.1 2.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX87884.1 - 3.5e-08 33.3 14.4 0.00091 19.4 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX87884.1 - 2.8e-05 24.1 7.1 2.8e-05 24.1 4.9 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX87884.1 - 0.24 11.8 19.8 0.63 10.5 2.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Aldedh PF00171.17 KFX87885.1 - 8.5e-188 624.3 0.5 9.6e-188 624.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF357 PF04010.8 KFX87885.1 - 0.082 12.6 0.6 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) ECH PF00378.15 KFX87886.1 - 2.1e-41 141.6 0.4 4.4e-41 140.6 0.2 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 2OG-FeII_Oxy_2 PF13532.1 KFX87894.1 - 5.6e-28 98.0 0.0 1.4e-27 96.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 KFX87894.1 - 1.6e-18 67.2 0.0 3.4e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy PF03171.15 KFX87894.1 - 0.008 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDC50 PF03381.10 KFX87896.1 - 6.3e-94 314.2 0.0 9.4e-94 313.6 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SAE2 PF08573.5 KFX87896.1 - 2.5e-28 98.6 0.1 7.7e-28 97.0 0.1 1.9 1 0 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SPT16 PF08644.6 KFX87897.1 - 1.2e-57 194.0 0.4 1.7e-56 190.3 0.1 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KFX87897.1 - 2e-54 183.5 0.1 6.2e-54 181.9 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 KFX87897.1 - 9.8e-21 73.5 0.0 2.8e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 KFX87897.1 - 1.1e-20 74.0 0.0 2.1e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Ish1 PF10281.4 KFX87897.1 - 0.032 14.3 0.0 0.15 12.1 0.0 2.2 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF2462 PF09495.5 KFX87898.1 - 2.8e-16 60.0 9.9 3.9e-16 59.5 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ERG4_ERG24 PF01222.12 KFX87899.1 - 5.4e-139 463.4 16.8 6.3e-139 463.2 11.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SRP-alpha_N PF04086.8 KFX87899.1 - 1.1 8.6 5.2 1.5 8.1 3.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal VCBS PF13517.1 KFX87900.1 - 2.6e-26 91.7 45.4 2.1e-11 43.9 1.0 5.9 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.1 KFX87900.1 - 9.9e-12 45.3 0.2 2e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX87900.1 - 1.6e-11 44.5 0.5 2.5e-11 43.8 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.18 KFX87900.1 - 1.1e-09 37.7 33.4 0.0023 17.5 0.2 5.8 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 KFX87900.1 - 0.00093 18.6 16.6 1.9 7.9 0.0 5.6 5 1 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region BBS2_C PF14782.1 KFX87900.1 - 0.014 13.9 0.6 4.4 5.7 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal EF-hand_5 PF13202.1 KFX87900.1 - 8.1 5.9 9.0 30 4.2 0.3 4.0 3 0 0 3 3 3 0 EF hand NIF PF03031.13 KFX87904.1 - 1.1e-39 135.6 0.0 1.6e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase PF00069.20 KFX87907.1 - 4.7e-69 232.4 0.0 6.4e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87907.1 - 1.5e-50 171.7 0.0 2.2e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX87907.1 - 0.00014 20.9 0.0 0.012 14.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Herpes_UL32 PF06070.6 KFX87907.1 - 1.9 6.8 16.4 2.7 6.3 11.3 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 tRNA-synt_1c PF00749.16 KFX87920.1 - 9.4e-95 316.8 0.0 1.2e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFX87920.1 - 2.6e-29 102.0 0.0 9.1e-29 100.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_60s PF00428.14 KFX87920.1 - 4.2 7.8 12.9 9.3 6.7 8.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Macro PF01661.16 KFX87921.1 - 1.9e-39 134.2 0.4 3e-39 133.5 0.3 1.3 1 0 0 1 1 1 1 Macro domain NMO PF03060.10 KFX87922.1 - 2.3e-49 168.3 0.2 3.3e-49 167.8 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ECH PF00378.15 KFX87922.1 - 1.1e-42 145.9 0.0 3e-42 144.4 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family FMN_dh PF01070.13 KFX87922.1 - 0.00066 18.6 1.6 0.0011 17.9 1.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KFX87922.1 - 0.0075 15.2 0.6 0.013 14.3 0.4 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peptidase_S49 PF01343.13 KFX87922.1 - 0.0087 15.8 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S49 Aldedh PF00171.17 KFX87923.1 - 2.1e-139 464.8 0.0 2.5e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX87923.1 - 1.6e-05 23.7 0.0 2.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Myb_Cef PF11831.3 KFX87924.1 - 1.2e-54 184.9 4.1 1.2e-54 184.9 2.9 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KFX87924.1 - 2.5e-20 72.2 4.9 1.5e-09 37.7 0.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX87924.1 - 9.1e-19 67.3 6.5 1.1e-13 51.0 1.2 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 KFX87924.1 - 0.36 10.7 3.3 0.55 10.1 0.0 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GILT PF03227.11 KFX87925.1 - 2.5e-14 53.0 0.1 4.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF2648 PF10855.3 KFX87925.1 - 0.11 11.9 0.9 0.23 10.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) AMP-binding PF00501.23 KFX87930.1 - 4.2e-40 137.4 0.2 5.5e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX87930.1 - 2.1e-16 60.6 0.0 5.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mucin PF01456.12 KFX87931.1 - 1.3 8.7 11.5 1.6 8.5 8.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TPPII_N PF12583.3 KFX87931.1 - 4.3 7.4 6.4 5.5 7.1 4.5 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Pal1 PF08316.6 KFX87934.1 - 7.4e-48 162.5 0.5 1.5e-47 161.5 0.4 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein DIOX_N PF14226.1 KFX87936.1 - 1.4e-18 67.5 0.0 2.8e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX87936.1 - 7.1e-13 48.7 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 KFX87937.1 - 8.4e-11 41.2 0.6 8.4e-11 41.2 0.4 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KFX87937.1 - 9.1e-07 28.4 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KFX87937.1 - 0.00081 19.0 0.1 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.17 KFX87937.1 - 0.0026 17.9 0.1 0.016 15.4 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 KFX87937.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FdtA PF05523.6 KFX87937.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal MFS_1 PF07690.11 KFX87938.1 - 2.2e-31 108.8 37.1 8.9e-31 106.8 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 KFX87938.1 - 0.28 10.6 1.3 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DIOX_N PF14226.1 KFX87939.1 - 2.5e-14 53.7 0.0 4.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX87939.1 - 2.1e-12 47.2 0.0 3.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 KFX87941.1 - 3.2e-29 102.1 0.1 1.6e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX87941.1 - 6.6e-06 25.2 0.2 0.025 13.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX87941.1 - 6.8e-06 25.2 0.0 0.33 9.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.5 KFX87941.1 - 8.5e-06 24.7 0.0 0.0017 17.2 0.0 2.4 2 0 0 2 2 2 2 Squalene epoxidase Amino_oxidase PF01593.19 KFX87941.1 - 0.00042 19.5 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 KFX87941.1 - 0.00043 19.0 0.0 0.098 11.2 0.0 2.8 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 KFX87941.1 - 0.00074 19.8 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX87941.1 - 0.0018 18.3 0.0 0.0079 16.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX87941.1 - 0.0018 18.2 0.3 0.0057 16.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX87941.1 - 0.0037 17.0 0.3 0.44 10.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KFX87941.1 - 0.0046 15.4 0.0 0.32 9.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFX87941.1 - 0.014 15.3 0.2 0.029 14.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX87941.1 - 0.06 12.1 0.2 0.12 11.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain KH_4 PF13083.1 KFX87942.1 - 0.17 11.5 0.5 2.8 7.6 0.1 2.0 1 1 1 2 2 2 0 KH domain OPT PF03169.10 KFX87946.1 - 3.5e-97 326.3 19.1 4e-97 326.1 13.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Grp1_Fun34_YaaH PF01184.14 KFX87948.1 - 7.6e-90 299.8 15.9 9.1e-90 299.5 11.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_transf_28 PF03033.15 KFX87950.1 - 5.6e-21 74.7 0.0 2.7e-20 72.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX87950.1 - 8.1e-05 21.3 0.0 0.00012 20.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFX87950.1 - 0.032 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Herpes_UL45 PF05473.7 KFX87950.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 UL45 protein ATG_C PF09333.6 KFX87950.1 - 0.13 12.4 0.0 0.83 9.8 0.0 2.1 2 0 0 2 2 2 0 ATG C terminal domain FA_hydroxylase PF04116.8 KFX87951.1 - 3.3e-05 24.2 7.6 3.3e-05 24.2 5.3 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CDP-OH_P_transf PF01066.16 KFX87952.1 - 8.6e-11 42.0 13.6 4e-10 39.8 9.4 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase AP4E_app_platf PF14807.1 KFX87953.1 - 0.3 11.3 2.3 0.78 10.0 1.4 1.8 1 1 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Ribonucleas_3_3 PF14622.1 KFX87954.1 - 2.3e-13 50.2 0.0 2.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFX87954.1 - 3.4e-09 37.1 0.0 1.2e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain YtxH PF12732.2 KFX87955.1 - 0.00027 21.2 0.1 0.00049 20.4 0.1 1.5 1 0 0 1 1 1 1 YtxH-like protein SLAC1 PF03595.12 KFX87956.1 - 2.2e-101 338.8 58.8 2.5e-101 338.6 40.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_17 PF00332.13 KFX87958.1 - 1.1e-06 27.8 1.0 0.0029 16.6 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 ETRAMP PF09716.5 KFX87958.1 - 0.021 14.7 0.1 0.021 14.7 0.1 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) adh_short PF00106.20 KFX87960.1 - 4.3e-20 72.3 0.0 7e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX87960.1 - 7.8e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX87960.1 - 4.5e-07 29.7 0.0 7.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain SET PF00856.23 KFX87966.1 - 2.7e-10 40.7 0.0 5.8e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 KFX87966.1 - 1.4e-05 24.8 9.7 1.4e-05 24.8 6.7 1.9 2 0 0 2 2 2 1 MYND finger Fer4_16 PF13484.1 KFX87966.1 - 0.0085 16.8 0.8 0.0085 16.8 0.6 3.1 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain zf-BED PF02892.10 KFX87966.1 - 0.02 14.6 0.5 0.02 14.6 0.3 2.4 2 0 0 2 2 2 0 BED zinc finger AhpC-TSA PF00578.16 KFX87967.1 - 1.1e-32 112.2 0.0 1.6e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFX87967.1 - 3.8e-13 49.2 0.0 5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFX87967.1 - 5.7e-11 41.8 0.1 1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.27 KFX87970.1 - 2.1e-05 24.1 0.1 0.14 12.1 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Tropomyosin_1 PF12718.2 KFX87972.1 - 8.6e-49 165.0 35.3 9.9e-49 164.8 24.4 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KFX87972.1 - 3.8e-10 39.2 31.2 9.2e-07 28.1 12.7 2.3 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 KFX87972.1 - 0.00025 20.3 29.3 0.00039 19.6 20.3 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cast PF10174.4 KFX87972.1 - 0.00031 18.9 27.3 0.00034 18.8 18.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 KFX87972.1 - 0.00038 20.0 33.2 0.0021 17.6 8.0 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Vps5 PF09325.5 KFX87972.1 - 0.0063 15.8 6.3 0.0063 15.8 4.4 2.8 1 1 1 3 3 3 1 Vps5 C terminal like EzrA PF06160.7 KFX87972.1 - 0.02 13.0 23.7 0.072 11.2 1.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.3 KFX87972.1 - 0.021 14.5 26.3 0.099 12.3 13.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KFX87972.1 - 0.023 14.3 29.3 3.2 7.3 20.3 2.5 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 KFX87972.1 - 0.03 14.2 32.0 0.033 14.0 1.4 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KFX87972.1 - 0.031 13.3 32.7 0.045 12.7 16.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 KFX87972.1 - 0.039 11.2 24.1 0.048 11.0 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFX87972.1 - 0.04 11.6 33.8 0.12 10.1 23.4 1.6 1 1 0 1 1 1 0 Myosin tail KLRAQ PF10205.4 KFX87972.1 - 0.043 13.8 19.8 0.043 13.8 7.0 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Rab5-bind PF09311.6 KFX87972.1 - 0.046 13.5 25.1 0.061 13.2 17.4 1.2 1 0 0 1 1 1 0 Rabaptin-like protein BLOC1_2 PF10046.4 KFX87972.1 - 0.047 13.8 21.5 0.81 9.8 6.8 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 KFX87972.1 - 0.048 12.5 25.4 0.029 13.3 12.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KFX87972.1 - 0.065 12.6 26.8 0.12 11.8 18.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein bZIP_1 PF00170.16 KFX87972.1 - 0.069 13.1 31.5 1.5 8.8 0.5 4.8 1 1 2 4 4 4 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 KFX87972.1 - 0.075 13.0 27.6 2.2 8.3 3.8 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 KFX87972.1 - 0.11 12.3 29.2 1.3 8.7 7.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 KFX87972.1 - 0.14 10.3 25.1 0.42 8.7 17.4 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 KFX87972.1 - 0.15 11.9 31.9 0.93 9.3 9.6 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 KFX87972.1 - 0.17 10.2 25.1 0.43 8.9 17.4 1.6 1 1 0 1 1 1 0 AAA domain NABP PF07990.7 KFX87972.1 - 0.18 11.0 5.8 0.19 10.9 4.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Laminin_II PF06009.7 KFX87972.1 - 0.25 11.1 18.8 0.21 11.3 4.0 2.7 1 1 1 2 2 2 0 Laminin Domain II WEMBL PF05701.6 KFX87972.1 - 0.28 9.5 32.7 0.18 10.2 18.7 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Jnk-SapK_ap_N PF09744.4 KFX87972.1 - 0.33 10.9 28.8 0.064 13.2 13.3 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Reo_sigmaC PF04582.7 KFX87972.1 - 0.37 9.9 2.8 4.9 6.2 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 KFX87972.1 - 0.4 10.0 29.3 1.5 8.2 20.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Spectrin PF00435.16 KFX87972.1 - 0.45 10.8 26.4 1.8 8.8 13.4 2.8 1 1 1 2 2 2 0 Spectrin repeat HlyD PF00529.15 KFX87972.1 - 0.52 9.5 9.9 0.71 9.1 6.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein MAD PF05557.8 KFX87972.1 - 0.52 8.3 28.5 1 7.3 11.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein bZIP_2 PF07716.10 KFX87972.1 - 0.54 10.1 35.6 0.13 12.1 3.3 5.2 3 1 3 6 6 6 0 Basic region leucine zipper Cortex-I_coil PF09304.5 KFX87972.1 - 0.56 10.2 27.0 5.4 7.1 5.2 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 KFX87972.1 - 0.58 10.4 10.6 19 5.5 0.0 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 KFX87972.1 - 0.62 10.3 38.4 4.8 7.5 5.9 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Spc7 PF08317.6 KFX87972.1 - 0.69 8.5 27.2 0.14 10.8 10.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 KFX87972.1 - 0.74 9.6 34.5 5 7.0 5.1 3.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 KFX87972.1 - 0.76 9.7 32.1 0.63 10.0 4.5 4.1 1 1 2 3 3 2 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 KFX87972.1 - 0.77 10.1 27.2 1.4 9.2 9.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) HOOK PF05622.7 KFX87972.1 - 0.78 7.4 25.4 1 7.0 17.6 1.2 1 0 0 1 1 1 0 HOOK protein HalX PF08663.5 KFX87972.1 - 0.8 9.7 18.6 7.3 6.6 0.1 4.2 2 2 2 4 4 4 0 HalX domain DUF812 PF05667.6 KFX87972.1 - 0.81 8.1 26.3 0.85 8.0 8.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) PilJ PF13675.1 KFX87972.1 - 0.83 9.9 11.6 1.6 9.0 1.9 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HAP1_N PF04849.8 KFX87972.1 - 0.89 8.4 28.2 34 3.2 19.6 3.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Striatin PF08232.7 KFX87972.1 - 0.98 9.7 25.0 0.95 9.7 12.0 2.2 1 1 1 2 2 2 0 Striatin family DUF3450 PF11932.3 KFX87972.1 - 1 8.5 22.0 1 8.5 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SPX PF03105.14 KFX87972.1 - 1.1 9.0 16.0 1.4 8.6 11.1 1.2 1 0 0 1 1 1 0 SPX domain FlaC_arch PF05377.6 KFX87972.1 - 1.2 9.0 18.8 1.3 8.9 1.7 4.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 KFX87972.1 - 1.2 9.0 32.3 3.7 7.5 12.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 KFX87972.1 - 1.4 8.7 14.3 3.8 7.3 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 KFX87972.1 - 1.7 8.1 31.6 1.2 8.6 10.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF3287 PF11690.3 KFX87972.1 - 1.9 8.5 11.8 1.3 9.1 3.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Fib_alpha PF08702.5 KFX87972.1 - 2.1 8.4 18.0 2.5 8.1 3.8 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KFX87972.1 - 2.2 8.0 32.3 2.3 7.9 7.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 KFX87972.1 - 2.5 7.6 19.5 0.22 11.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.6 KFX87972.1 - 2.7 8.4 17.5 13 6.2 4.4 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Mnd1 PF03962.10 KFX87972.1 - 3 7.4 29.0 6.5 6.3 8.8 2.1 1 1 1 2 2 2 0 Mnd1 family Lebercilin PF15619.1 KFX87972.1 - 3.2 7.1 31.8 82 2.5 11.9 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HSP70 PF00012.15 KFX87972.1 - 3.3 5.5 19.5 4.1 5.1 13.5 1.2 1 0 0 1 1 1 0 Hsp70 protein Fmp27_WPPW PF10359.4 KFX87972.1 - 3.9 5.7 24.0 0.37 9.1 5.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CDC37_N PF03234.9 KFX87972.1 - 4 7.7 24.3 1.1e+02 3.0 16.8 2.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding FlaF PF07309.6 KFX87972.1 - 4.4 7.2 9.0 0.46 10.3 1.0 2.5 1 1 2 3 3 3 0 Flagellar protein FlaF Cep57_MT_bd PF06657.8 KFX87972.1 - 4.5 7.3 19.9 0.33 10.9 2.1 3.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Orbi_VP5 PF00901.12 KFX87972.1 - 4.5 5.3 18.3 2.9 5.9 11.7 1.3 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 STAT_alpha PF01017.15 KFX87972.1 - 4.9 6.8 18.6 2.5 7.7 0.2 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Prefoldin PF02996.12 KFX87972.1 - 5 6.7 28.2 2 8.0 3.2 4.0 1 1 3 4 4 4 0 Prefoldin subunit OmpH PF03938.9 KFX87972.1 - 5.7 6.8 28.7 2.7e+03 -1.9 19.9 2.2 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 KFX87972.1 - 7.1 4.9 26.1 0.79 8.0 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 KFX87972.1 - 7.2 7.1 21.0 66 4.0 0.1 3.3 1 1 1 2 2 1 0 N-terminal domain of unknown function (DUF4140) Nup54 PF13874.1 KFX87972.1 - 8.5 6.0 23.3 10 5.7 1.9 3.0 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF4559 PF15112.1 KFX87972.1 - 8.5 5.4 20.1 15 4.6 13.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Nop25 PF09805.4 KFX87973.1 - 2.4e-31 108.6 11.8 2.4e-31 108.6 8.2 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Dala_Dala_lig_N PF01820.16 KFX87973.1 - 2.1 8.6 7.5 11 6.3 1.7 2.6 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus ATP-synt_S1 PF05827.7 KFX87974.1 - 3.7e-26 92.0 0.0 8.3e-26 90.9 0.0 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3176 PF11374.3 KFX87974.1 - 0.65 9.8 3.7 2.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3176) Fcf1 PF04900.7 KFX87975.1 - 2.7e-40 136.5 0.2 4.8e-40 135.7 0.1 1.4 1 0 0 1 1 1 1 Fcf1 vMSA PF00695.14 KFX87976.1 - 0.12 11.5 2.4 0.17 11.0 1.7 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus UbiA PF01040.13 KFX87976.1 - 0.13 11.4 1.9 0.16 11.1 0.4 1.7 1 1 1 2 2 2 0 UbiA prenyltransferase family DUF1049 PF06305.6 KFX87976.1 - 0.63 9.5 2.6 1.5 8.3 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Methyltransf_11 PF08241.7 KFX87978.1 - 1.6e-20 73.3 0.1 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87978.1 - 1.8e-16 60.1 0.0 2.2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX87978.1 - 6.5e-16 58.4 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX87978.1 - 7.5e-13 49.0 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX87978.1 - 2.3e-12 46.9 0.1 4.7e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX87978.1 - 7.7e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX87978.1 - 1.3e-11 44.1 0.0 1.8e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KFX87978.1 - 5.8e-11 42.6 0.1 1.1e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX87978.1 - 1.7e-09 37.1 0.0 2.9e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFX87978.1 - 1.7e-07 30.8 0.0 2.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFX87978.1 - 2.1e-07 30.6 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KFX87978.1 - 2.8e-06 27.0 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 KFX87978.1 - 1.3e-05 24.0 0.0 1.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.5 KFX87978.1 - 6.4e-05 22.5 0.0 8.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 KFX87978.1 - 6.6e-05 22.6 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX87978.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DUF633 PF04816.7 KFX87978.1 - 0.0002 20.7 0.1 0.00029 20.2 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) PrmA PF06325.8 KFX87978.1 - 0.00024 20.3 0.1 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 KFX87978.1 - 0.00052 19.2 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.6 KFX87978.1 - 0.0006 19.3 0.0 0.00096 18.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 KFX87978.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) GCD14 PF08704.5 KFX87978.1 - 0.0025 17.3 0.1 0.0059 16.1 0.0 1.5 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 KFX87978.1 - 0.0081 16.9 0.1 0.015 16.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFX87978.1 - 0.0098 14.9 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KFX87978.1 - 0.057 12.4 0.0 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.10 KFX87978.1 - 0.14 11.8 0.0 1.3 8.5 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.1 KFX87982.1 - 2.1e-07 30.6 0.3 2.9e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFX87982.1 - 0.0017 17.7 0.2 0.003 16.8 0.1 1.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.14 KFX87982.1 - 0.028 13.9 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KFX87982.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 KFX87983.1 - 0.00028 20.7 13.7 0.00046 20.0 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX87983.1 - 0.016 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain RTA1 PF04479.8 KFX87985.1 - 2.8e-50 170.9 4.4 2.8e-50 170.9 3.1 1.9 2 0 0 2 2 2 1 RTA1 like protein AstE_AspA PF04952.9 KFX87986.1 - 1.1e-25 90.1 0.0 3.8e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Succinylglutamate desuccinylase / Aspartoacylase family MFS_1 PF07690.11 KFX87987.1 - 1.5e-35 122.5 31.9 2.2e-35 121.9 22.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KFX87987.1 - 0.00079 19.4 5.5 0.0041 17.1 0.4 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1228) DUF872 PF05915.7 KFX87987.1 - 1.2 9.0 4.5 14 5.5 0.1 3.5 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Sec1 PF00995.18 KFX87988.1 - 1.4e-122 410.2 0.1 1.7e-122 409.9 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Cyclin PF08613.6 KFX87991.1 - 3.4e-38 131.3 0.2 1e-22 81.1 0.2 2.4 2 0 0 2 2 2 2 Cyclin Pkinase PF00069.20 KFX88000.1 - 1.2e-11 44.3 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX88000.1 - 1.6e-05 24.7 0.9 2.8e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFX88000.1 - 0.00017 20.7 0.0 0.00023 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX88000.1 - 0.00025 20.1 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX88000.1 - 0.0089 15.3 0.1 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFX88000.1 - 0.17 11.4 0.8 0.27 10.7 0.6 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fungal_trans_2 PF11951.3 KFX88001.1 - 1.9e-74 250.5 0.0 2.4e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88001.1 - 1.7e-07 31.0 10.9 3e-07 30.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERO1 PF04137.10 KFX88002.1 - 1.7e-134 448.3 0.0 3.1e-134 447.4 0.0 1.4 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pal1 PF08316.6 KFX88003.1 - 5.4e-05 23.6 0.1 0.00012 22.5 0.1 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 KFX88004.1 - 1.1e-76 257.0 0.0 1.3e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein PSP1 PF04468.7 KFX88008.1 - 3.4e-30 103.8 0.9 5.8e-30 103.1 0.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NifU PF01106.12 KFX88009.1 - 5.1e-21 74.2 0.1 7.7e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 KFX88009.1 - 7.6e-19 67.1 0.0 2.3e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal DUF2052 PF09747.4 KFX88011.1 - 2.1e-14 53.8 0.0 3.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Y_phosphatase3 PF13350.1 KFX88012.1 - 3e-44 151.1 0.0 7.5e-44 149.8 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFX88012.1 - 1.7e-12 47.2 0.0 1.7e-11 44.0 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KFX88012.1 - 3e-05 23.4 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFX88012.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family HTH_Tnp_1 PF01527.15 KFX88012.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase Yip1 PF04893.12 KFX88018.1 - 5.2e-13 48.8 14.2 5.2e-13 48.8 9.8 1.7 1 1 1 2 2 2 1 Yip1 domain Glyco_hydro_26 PF02156.10 KFX88019.1 - 2.7e-83 280.0 1.1 3.6e-83 279.6 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 VirC2 PF07181.6 KFX88019.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 VirC2 protein Methyltransf_11 PF08241.7 KFX88020.1 - 3.5e-16 59.4 0.0 5.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX88020.1 - 8e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX88020.1 - 7.7e-10 39.3 0.0 1.3e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX88020.1 - 2.6e-09 36.8 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX88020.1 - 3.2e-08 33.4 0.0 5.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX88020.1 - 4.9e-07 30.0 0.0 8.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KFX88020.1 - 0.00014 20.8 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_26 PF13659.1 KFX88020.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX88020.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KFX88020.1 - 0.003 16.6 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 KFX88020.1 - 0.028 13.1 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 KFX88020.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.6 KFX88020.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) EF-hand_7 PF13499.1 KFX88021.1 - 2.8e-13 49.8 0.5 1.1e-09 38.3 0.3 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KFX88021.1 - 1.5e-10 40.0 0.3 0.0058 16.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFX88021.1 - 1.5e-08 33.3 0.1 0.013 14.7 0.0 3.7 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFX88021.1 - 5.6e-07 29.3 0.0 0.032 14.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFX88021.1 - 4.6e-06 26.1 0.3 0.00067 19.2 0.1 3.3 2 2 2 4 4 4 1 EF-hand domain pair UPF0154 PF03672.8 KFX88021.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 KFX88021.1 - 0.056 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_5 PF13202.1 KFX88021.1 - 4 6.9 5.4 2.2 7.7 0.7 2.6 2 0 0 2 2 2 0 EF hand ABC_membrane PF00664.18 KFX88026.1 - 6.6e-84 281.5 25.0 2.4e-42 145.2 6.3 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX88026.1 - 1.9e-49 167.4 0.0 9.5e-29 100.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX88026.1 - 3.2e-09 36.3 4.0 0.0093 15.2 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFX88026.1 - 4.7e-06 26.7 2.2 0.011 15.7 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KFX88026.1 - 2e-05 24.7 0.1 0.68 9.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KFX88026.1 - 3.6e-05 23.6 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KFX88026.1 - 7.6e-05 22.1 0.1 0.19 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFX88026.1 - 0.00036 21.0 0.3 1.1 9.7 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFX88026.1 - 0.00041 19.8 1.3 1.1 8.7 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFX88026.1 - 0.00053 19.5 0.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 KFX88026.1 - 0.00071 18.8 0.2 0.26 10.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX88026.1 - 0.00073 19.9 0.4 0.12 12.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 KFX88026.1 - 0.001 18.9 0.8 0.13 12.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 KFX88026.1 - 0.0022 16.9 0.0 0.12 11.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KFX88026.1 - 0.0038 16.6 0.1 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KFX88026.1 - 0.018 15.8 0.2 1.9 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KFX88026.1 - 0.035 13.6 0.9 9.2 5.7 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KFX88026.1 - 0.097 12.3 0.3 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFX88026.1 - 0.1 12.2 0.2 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KFX88026.1 - 0.11 12.6 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KFX88026.1 - 0.29 11.2 1.5 13 5.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 KFX88026.1 - 0.46 9.5 2.0 6.1 5.8 0.1 2.5 2 0 0 2 2 2 0 AIG1 family DUF87 PF01935.12 KFX88026.1 - 1.4 8.7 10.5 1.5 8.5 0.1 2.9 4 0 0 4 4 2 0 Domain of unknown function DUF87 HLH PF00010.21 KFX88027.1 - 3.6e-12 45.7 0.2 6.5e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CLTH PF10607.4 KFX88028.1 - 5.7e-33 113.6 0.2 1.2e-32 112.6 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFX88028.1 - 0.011 15.5 0.0 0.032 13.9 0.0 1.9 1 0 0 1 1 1 0 LisH NDUF_B12 PF08122.7 KFX88029.1 - 3.6e-17 61.8 0.5 5.6e-17 61.2 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Thiolase_N PF00108.18 KFX88031.1 - 2.4e-95 318.5 0.4 3.4e-95 318.0 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX88031.1 - 3.3e-38 129.8 0.4 3.3e-38 129.8 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFX88031.1 - 2e-05 24.2 2.4 3.4e-05 23.4 0.7 2.0 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain TFIIA PF03153.8 KFX88032.1 - 9.6 5.9 11.9 11 5.7 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldo_ket_red PF00248.16 KFX88033.1 - 6.9e-51 172.7 0.0 8.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Esterase_phd PF10503.4 KFX88034.1 - 6.6e-24 84.3 2.8 8.7e-24 83.9 1.9 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX88034.1 - 9e-14 51.2 0.5 1.3e-13 50.6 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX88034.1 - 7.3e-09 35.5 0.5 1.1e-08 34.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX88034.1 - 1.4e-05 25.1 0.3 4.3e-05 23.4 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family CBM_1 PF00734.13 KFX88034.1 - 0.0003 20.3 7.5 0.0003 20.3 5.2 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_1 PF00561.15 KFX88034.1 - 0.0021 17.6 0.1 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFX88034.1 - 0.021 14.2 2.0 0.045 13.1 1.4 1.6 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.8 KFX88034.1 - 0.053 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COesterase PF00135.23 KFX88034.1 - 0.084 11.5 2.6 0.046 12.4 0.2 1.8 2 0 0 2 2 2 0 Carboxylesterase family Ribonuclease PF00545.15 KFX88035.1 - 4.3e-20 71.5 0.1 1.3e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 ribonuclease Flavi_NS1 PF00948.16 KFX88035.1 - 0.0097 14.3 0.1 0.01 14.3 0.1 1.1 1 0 0 1 1 1 1 Flavivirus non-structural Protein NS1 DUF3632 PF12311.3 KFX88036.1 - 3.6e-36 124.6 0.4 4.4e-36 124.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Epimerase PF01370.16 KFX88037.1 - 2.5e-12 46.7 0.0 3.7e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX88037.1 - 5.9e-11 42.6 0.9 1.3e-10 41.5 0.6 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX88037.1 - 5.8e-08 32.2 0.5 1.1e-07 31.3 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KFX88037.1 - 1.8e-07 31.2 0.1 3.3e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFX88037.1 - 3.3e-05 22.9 0.5 0.00021 20.3 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFX88037.1 - 8.3e-05 21.6 0.0 0.00025 20.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFX88037.1 - 0.00039 19.2 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFX88037.1 - 0.00066 18.6 0.1 0.066 12.0 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 KFX88037.1 - 0.0065 16.1 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KFX88037.1 - 0.012 16.0 0.1 0.035 14.5 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KFX88037.1 - 0.027 13.8 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 KFX88037.1 - 0.067 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NUDIX_2 PF13869.1 KFX88038.1 - 4.2e-82 274.0 0.0 5e-82 273.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 KFX88039.1 - 2.5e-40 136.9 0.0 6.8e-40 135.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.13 KFX88039.1 - 4.8e-13 48.5 0.0 1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88039.1 - 4.6e-08 32.8 10.2 7.7e-08 32.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 KFX88042.1 - 3.7e-32 111.2 0.0 4.6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX88042.1 - 6.5e-12 46.2 0.0 1.9e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain ChaC PF04752.7 KFX88046.1 - 3e-57 193.4 0.0 3.6e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Epimerase PF01370.16 KFX88047.1 - 1.5e-10 40.9 0.1 1e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX88047.1 - 2.3e-06 26.5 0.2 6.1e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX88047.1 - 4.3e-05 23.5 0.3 7.2e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX88047.1 - 0.00054 19.2 0.3 0.00085 18.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KFX88047.1 - 0.0018 18.2 0.2 0.0027 17.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX88047.1 - 0.0019 17.8 0.2 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KFX88047.1 - 0.0019 18.1 0.3 0.0043 17.0 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 KFX88047.1 - 0.0024 16.7 0.2 0.21 10.4 0.1 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFX88047.1 - 0.017 14.0 1.3 0.13 11.1 0.5 2.3 2 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 KFX88047.1 - 0.046 12.6 0.2 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Rhodanese PF00581.15 KFX88047.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.9 2 1 0 2 2 2 0 Rhodanese-like domain Zn_clus PF00172.13 KFX88048.1 - 4.6e-07 29.6 10.6 1e-06 28.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3142 PF11340.3 KFX88048.1 - 0.099 12.2 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) RRM_1 PF00076.17 KFX88050.1 - 2.5e-21 75.0 0.0 3.1e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88050.1 - 2.5e-16 59.3 0.0 3.1e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88050.1 - 2.4e-09 36.9 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFX88056.1 - 5.9e-139 447.5 32.3 3.6e-14 51.9 0.1 12.5 12 0 0 12 12 12 11 WD domain, G-beta repeat NACHT PF05729.7 KFX88056.1 - 3.6e-12 46.2 0.1 1.4e-11 44.3 0.2 1.9 2 0 0 2 2 2 1 NACHT domain PD40 PF07676.7 KFX88056.1 - 3.3e-10 39.3 0.2 13 5.6 0.0 9.1 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFX88056.1 - 2.2e-09 37.3 4.6 0.011 15.4 0.0 4.2 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A DUF1258 PF06869.7 KFX88056.1 - 0.0037 16.4 0.9 3 6.8 0.0 4.6 2 1 2 5 5 5 1 Protein of unknown function (DUF1258) Epimerase PF01370.16 KFX88056.1 - 0.01 15.2 0.1 0.047 13.1 0.0 2.2 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Thiolase_C PF02803.13 KFX88064.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Thiolase, C-terminal domain PAP1 PF08601.5 KFX88064.1 - 0.17 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 AA_permease_2 PF13520.1 KFX88066.1 - 2e-50 171.5 53.1 2.5e-50 171.2 36.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX88066.1 - 8.7e-23 80.4 44.9 1.2e-22 79.9 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 KFX88068.1 - 7.8e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX88068.1 - 2.1e-09 37.3 0.0 8.3e-09 35.4 0.0 2.0 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX88068.1 - 1.5e-06 28.2 0.0 4e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX88068.1 - 4.3e-05 23.3 0.0 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX88068.1 - 0.0032 17.3 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KFX88068.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Cu-oxidase_3 PF07732.10 KFX88072.1 - 4.9e-37 126.2 0.5 3.6e-36 123.4 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX88072.1 - 8.3e-27 93.3 2.6 5.1e-20 71.3 0.1 4.4 4 1 1 5 5 5 3 Multicopper oxidase Cu-oxidase PF00394.17 KFX88072.1 - 3.7e-13 49.6 0.0 9.3e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Multicopper oxidase COesterase PF00135.23 KFX88075.1 - 4.1e-93 312.9 0.0 5.9e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF1264 PF06884.6 KFX88075.1 - 2.7e-75 251.4 0.0 4.2e-75 250.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Abhydrolase_3 PF07859.8 KFX88075.1 - 0.0096 15.5 0.1 0.026 14.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold ABC_membrane PF00664.18 KFX88076.1 - 2.9e-71 240.0 28.2 6.8e-40 137.2 6.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX88076.1 - 9.7e-65 217.0 0.1 5.9e-32 110.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX88076.1 - 8.1e-14 51.3 0.1 0.00016 21.0 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX88076.1 - 2.6e-11 44.0 0.1 0.021 14.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KFX88076.1 - 2.8e-07 31.3 0.0 0.017 15.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KFX88076.1 - 6.9e-07 28.7 0.4 0.019 14.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFX88076.1 - 6.5e-06 25.4 0.1 0.097 11.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KFX88076.1 - 6.5e-06 25.9 1.1 0.2 11.5 0.1 4.0 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KFX88076.1 - 1.5e-05 25.1 2.9 1.2 9.2 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX88076.1 - 1.6e-05 24.3 0.2 0.31 10.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 KFX88076.1 - 3e-05 24.3 0.1 0.36 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX88076.1 - 5.3e-05 23.2 3.0 0.078 12.9 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.1 KFX88076.1 - 0.00072 19.1 0.6 2 7.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KFX88076.1 - 0.0026 17.6 0.1 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX88076.1 - 0.0031 16.6 0.0 0.77 8.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KFX88076.1 - 0.0032 16.1 0.2 0.95 7.9 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_5 PF07728.9 KFX88076.1 - 0.0099 15.6 0.3 4.5 6.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 KFX88076.1 - 0.01 15.5 0.3 5.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 KFX88076.1 - 0.036 13.7 0.3 2.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KFX88076.1 - 0.04 13.6 2.0 11 5.8 0.0 3.5 3 0 0 3 3 3 0 Part of AAA domain AAA PF00004.24 KFX88076.1 - 0.079 13.1 1.0 39 4.4 0.0 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.7 KFX88076.1 - 0.081 12.0 0.1 8.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 KFX88076.1 - 0.48 10.7 0.9 25 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.1 KFX88077.1 - 2e-26 92.8 0.0 8.8e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX88077.1 - 0.0075 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MFS_1 PF07690.11 KFX88078.1 - 8.9e-11 41.0 60.6 1.4e-10 40.4 36.8 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Esterase PF00756.15 KFX88079.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KFX88079.1 - 2.8e-06 26.7 0.0 4.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFX88079.1 - 0.00048 20.0 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX88079.1 - 0.0022 17.7 0.0 0.0037 17.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX88079.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.13 KFX88083.1 - 1.2e-08 34.7 7.1 1.7e-08 34.2 4.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.16 KFX88085.1 - 2.4e-204 679.6 0.9 3.3e-204 679.1 0.6 1.2 1 0 0 1 1 1 1 Dehydratase family Pkinase PF00069.20 KFX88085.1 - 1.5e-47 161.9 0.0 2.2e-46 158.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88085.1 - 9.2e-27 93.7 0.0 2.1e-26 92.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX88085.1 - 0.42 9.5 0.0 7.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Kinase-like DUF605 PF04652.11 KFX88088.1 - 0.066 12.5 19.8 0.083 12.2 13.7 1.1 1 0 0 1 1 1 0 Vta1 like Nop25 PF09805.4 KFX88089.1 - 0.19 11.8 8.5 0.27 11.3 5.9 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Med3 PF11593.3 KFX88089.1 - 0.52 9.4 3.8 0.54 9.4 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EBV-NA3 PF05009.7 KFX88092.1 - 1.3 8.2 6.2 0.23 10.7 0.1 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Cpn60_TCP1 PF00118.19 KFX88093.1 - 8.2e-116 387.4 9.6 9.7e-116 387.2 6.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 KFX88093.1 - 2.5e-25 88.8 0.1 5.5e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NOPS PF08075.6 KFX88093.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 NOPS (NUC059) domain Blt1 PF12754.2 KFX88094.1 - 3.1e-28 99.2 0.5 5.1e-21 75.5 0.1 2.4 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KFX88094.1 - 0.063 12.6 0.1 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family Nol1_Nop2_Fmu PF01189.12 KFX88095.1 - 3.5e-100 335.0 0.0 1.4e-99 333.0 0.0 1.9 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFX88095.1 - 0.004 16.7 2.0 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KFX88095.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fungal_trans_2 PF11951.3 KFX88096.1 - 3.6e-19 68.6 4.3 7.3e-19 67.6 3.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88096.1 - 2.5e-07 30.5 13.4 4.3e-07 29.7 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydro_lipase PF04083.11 KFX88096.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NmrA PF05368.8 KFX88097.1 - 1.3e-32 112.9 0.0 1.8e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX88097.1 - 4.3e-07 30.1 0.1 1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX88097.1 - 8.3e-06 24.7 0.0 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFX88097.1 - 0.0035 17.0 0.1 0.01 15.5 0.2 1.8 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 KFX88097.1 - 0.0056 16.6 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX88097.1 - 0.022 14.1 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_15 PF09445.5 KFX88097.1 - 0.17 11.4 0.0 0.75 9.3 0.0 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase ATP-synt_Eps PF04627.8 KFX88101.1 - 2.5e-18 65.3 1.2 2.5e-18 65.3 0.8 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 KFX88102.1 - 1.3e-47 161.1 0.2 2.6e-47 160.1 0.1 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FCH PF00611.18 KFX88103.1 - 4.2e-21 74.9 2.0 4.4e-21 74.8 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KFX88103.1 - 6.1e-13 47.9 0.0 1.4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFX88103.1 - 1.4e-10 40.5 0.0 9.7e-10 37.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KFX88103.1 - 1.4e-09 37.3 0.0 3.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Not1 PF04054.10 KFX88104.1 - 4.1e-130 434.0 0.0 8.1e-130 433.0 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KFX88104.1 - 1.3e-43 148.2 5.8 4e-43 146.6 4.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Avirulence PF03377.8 KFX88104.1 - 0.023 13.4 0.1 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA NTF2 PF02136.15 KFX88106.1 - 9.1e-29 100.2 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.4 KFX88107.1 - 8.3e-41 138.5 13.1 9.9e-41 138.2 9.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF3566 PF12089.3 KFX88107.1 - 0.64 10.0 6.1 0.72 9.8 3.6 1.5 1 1 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) CbiQ PF02361.11 KFX88107.1 - 0.81 9.2 10.4 1.1 8.8 7.2 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF3210 PF11489.3 KFX88108.1 - 6.6e-201 669.7 71.8 6.6e-201 669.7 49.7 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Plasmodium_HRP PF05403.6 KFX88108.1 - 2e-06 27.5 8.7 9.1e-06 25.3 6.5 1.6 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) RNase_H2-Ydr279 PF09468.5 KFX88109.1 - 9.7e-91 304.1 0.0 1.2e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 KFX88110.1 - 1.3e-18 66.3 1.3 2.4e-18 65.4 0.9 1.5 1 0 0 1 1 1 1 Primase zinc finger MutS_V PF00488.16 KFX88111.1 - 3.4e-53 180.4 0.0 5.9e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX88111.1 - 8.8e-21 74.6 0.0 1.9e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MMgT PF10270.4 KFX88112.1 - 9.9e-35 119.1 0.0 1.1e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 KFX88113.1 - 3.5e-30 103.5 1.2 6.3e-30 102.7 0.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFX88113.1 - 6.5e-14 51.7 8.0 6.5e-14 51.7 5.5 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KFX88113.1 - 0.00032 21.1 0.1 0.00077 19.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX88113.1 - 0.0054 16.6 0.6 0.02 14.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 KFX88113.1 - 0.13 11.9 1.7 0.18 11.4 1.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AAA_2 PF07724.9 KFX88114.1 - 3.9e-46 157.0 0.3 7.7e-45 152.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KFX88114.1 - 4.8e-26 90.4 0.3 4.8e-26 90.4 0.2 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KFX88114.1 - 2.1e-20 73.2 0.1 1.4e-10 41.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX88114.1 - 2.8e-13 49.7 0.0 6.5e-09 35.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX88114.1 - 1.4e-10 41.5 11.6 0.00032 20.7 0.0 5.3 4 2 1 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 KFX88114.1 - 1.4e-09 38.1 0.0 0.0016 18.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KFX88114.1 - 4.7e-08 32.6 0.4 1.7e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KFX88114.1 - 1.6e-07 31.1 0.0 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 KFX88114.1 - 8.5e-06 25.6 0.0 0.075 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFX88114.1 - 9.4e-06 25.1 0.1 0.12 11.7 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 KFX88114.1 - 1.9e-05 25.4 4.1 0.027 15.2 0.0 3.7 2 2 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KFX88114.1 - 3.4e-05 23.5 0.0 0.057 13.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KFX88114.1 - 6e-05 23.3 5.9 0.14 12.4 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 KFX88114.1 - 8.9e-05 22.4 0.7 0.062 13.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KFX88114.1 - 0.00011 22.0 10.7 0.084 12.5 0.7 4.3 3 2 0 3 3 2 2 Archaeal ATPase MobB PF03205.9 KFX88114.1 - 0.00015 21.5 0.0 0.82 9.3 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFX88114.1 - 0.00082 19.6 0.5 0.86 9.8 0.0 3.4 3 0 0 3 3 3 1 ABC transporter IncA PF04156.9 KFX88114.1 - 0.0011 18.6 10.2 0.0011 18.6 7.0 1.8 2 0 0 2 2 1 1 IncA protein RNA_helicase PF00910.17 KFX88114.1 - 0.0013 18.8 0.0 0.76 9.9 0.0 3.0 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KFX88114.1 - 0.0016 17.6 0.0 0.53 9.4 0.0 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KFX88114.1 - 0.002 17.6 0.7 0.035 13.5 0.1 3.1 2 2 1 3 3 2 1 AAA-like domain AAA_25 PF13481.1 KFX88114.1 - 0.002 17.5 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KFX88114.1 - 0.0035 16.2 0.3 0.079 11.8 0.1 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KFX88114.1 - 0.0043 16.1 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 KFX88114.1 - 0.0045 16.5 2.0 0.35 10.4 0.0 4.0 4 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 KFX88114.1 - 0.0054 15.9 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PhoH PF02562.11 KFX88114.1 - 0.0056 15.9 0.0 0.97 8.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mnd1 PF03962.10 KFX88114.1 - 0.0075 15.9 10.9 0.015 14.9 7.5 1.4 1 0 0 1 1 1 1 Mnd1 family AAA_33 PF13671.1 KFX88114.1 - 0.01 15.6 0.0 4.8 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFX88114.1 - 0.016 15.7 0.1 0.23 11.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein OmpH PF03938.9 KFX88114.1 - 0.017 15.1 1.1 0.043 13.7 0.8 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TrwB_AAD_bind PF10412.4 KFX88114.1 - 0.022 13.3 0.1 2.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 KFX88114.1 - 0.023 14.2 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KFX88114.1 - 0.025 14.0 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.10 KFX88114.1 - 0.028 14.2 2.7 2.3 7.9 0.0 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KFX88114.1 - 0.034 13.0 0.0 1.9 7.3 0.0 2.6 3 0 0 3 3 2 0 PIF1-like helicase AFG1_ATPase PF03969.11 KFX88114.1 - 0.038 12.7 0.0 0.11 11.2 0.0 1.8 1 0 0 1 1 1 0 AFG1-like ATPase UPF0079 PF02367.12 KFX88114.1 - 0.058 13.0 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KFX88114.1 - 0.075 12.5 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KFX88114.1 - 0.091 11.6 0.0 8.1 5.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Zw10 PF06248.8 KFX88114.1 - 0.12 10.4 2.4 0.23 9.5 1.2 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 AAA_15 PF13175.1 KFX88114.1 - 0.2 10.6 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Atg14 PF10186.4 KFX88114.1 - 0.43 9.4 7.6 0.92 8.3 5.2 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFX88114.1 - 0.59 7.9 2.2 0.84 7.4 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 KFX88114.1 - 4.3 7.3 17.0 5.6 7.0 9.5 3.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain OEP PF02321.13 KFX88114.1 - 8.3 5.9 12.8 16 5.0 8.9 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DUF4349 PF14257.1 KFX88114.1 - 9.4 5.3 14.7 2.7 7.1 1.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) AdoHcyase PF05221.12 KFX88115.1 - 4.6e-137 455.3 0.2 5.3e-137 455.1 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFX88115.1 - 5.6e-83 276.6 3.2 8.5e-83 276.0 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX88115.1 - 1.8e-07 30.4 0.1 4.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KFX88115.1 - 0.00061 19.4 0.7 0.0013 18.3 0.4 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 KFX88115.1 - 0.0012 18.2 0.5 0.0022 17.3 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 KFX88115.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein TrkA_N PF02254.13 KFX88115.1 - 0.078 12.9 0.1 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KFX88115.1 - 0.089 12.4 0.5 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain JAB PF01398.16 KFX88116.1 - 7e-08 32.2 0.5 7e-07 28.9 0.4 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.22 KFX88118.1 - 3.9e-46 154.6 0.5 1.9e-18 65.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 KFX88121.1 - 3.6e-16 58.5 0.0 7.8e-13 47.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88121.1 - 1.9e-09 37.3 0.0 2e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DLIC PF05783.6 KFX88122.1 - 6.1e-35 120.8 0.1 4e-33 114.7 0.0 3.0 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 KFX88123.1 - 1.6e-18 66.0 0.0 3.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88123.1 - 2.2e-14 53.1 0.0 4.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88123.1 - 8.4e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFX88124.1 - 4.3e-11 42.2 0.4 0.00072 19.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 KFX88124.1 - 0.23 9.2 0.0 0.37 8.5 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Septin PF00735.13 KFX88125.1 - 3.4e-106 354.3 0.1 8.4e-106 353.0 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFX88125.1 - 5.3e-06 26.3 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 KFX88125.1 - 0.0005 18.9 0.1 0.00095 18.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 KFX88125.1 - 0.00081 19.2 7.2 0.011 15.6 0.1 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KFX88125.1 - 0.0042 16.5 0.0 0.13 11.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFX88125.1 - 0.013 14.6 0.3 0.039 13.1 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 KFX88125.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.22 KFX88125.1 - 0.017 15.3 0.4 0.1 12.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 KFX88125.1 - 0.024 15.1 0.3 0.062 13.8 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 KFX88125.1 - 0.05 14.4 5.6 0.052 14.3 0.2 2.8 2 2 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX88125.1 - 0.063 12.6 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.7 KFX88125.1 - 0.082 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.1 KFX88125.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain FMN_bind PF04205.9 KFX88125.1 - 0.16 12.1 0.5 1.1 9.5 0.0 2.4 3 0 0 3 3 3 0 FMN-binding domain FtsK_SpoIIIE PF01580.13 KFX88125.1 - 0.17 11.3 0.2 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KFX88125.1 - 0.19 11.5 3.2 0.84 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3653 PF12375.3 KFX88125.1 - 0.27 11.4 1.3 6.4 7.0 0.2 2.6 2 1 0 2 2 2 0 Phage protein Bax1-I PF01027.15 KFX88126.1 - 8e-49 166.0 28.2 9.3e-49 165.8 19.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 KFX88126.1 - 0.0076 15.4 11.2 0.014 14.5 7.7 1.4 1 1 0 1 1 1 1 Bax inhibitor 1 like NfeD PF01957.13 KFX88126.1 - 8.7 6.4 13.3 0.74 9.9 0.9 2.8 1 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding SH3_1 PF00018.23 KFX88127.1 - 9.3e-09 34.5 0.1 1.5e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX88127.1 - 1.1e-06 28.0 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX88127.1 - 3.2e-06 26.5 0.0 6.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Aa_trans PF01490.13 KFX88129.1 - 2.1e-92 309.7 21.4 3.1e-92 309.1 14.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFX88129.1 - 1.3e-08 34.1 20.0 1.3e-08 34.1 13.9 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Ribosomal_S16 PF00886.14 KFX88130.1 - 5.5e-26 90.0 0.1 9e-26 89.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 KFX88131.1 - 1.1e-34 119.5 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ras PF00071.17 KFX88132.1 - 3.9e-52 175.9 0.0 4.6e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX88132.1 - 9.1e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX88132.1 - 1.6e-10 40.4 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX88132.1 - 9.9e-07 28.3 0.0 5.5e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX88132.1 - 3e-05 23.9 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX88132.1 - 0.0047 17.0 0.1 0.041 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX88132.1 - 0.0047 16.9 0.5 0.49 10.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.7 KFX88132.1 - 0.024 13.7 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFX88132.1 - 0.046 12.4 0.0 0.075 11.7 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 KFX88132.1 - 0.12 11.7 0.1 0.34 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain WSC PF01822.14 KFX88134.1 - 9.6e-36 121.5 66.4 2.6e-14 52.9 4.3 5.9 5 0 0 5 5 5 3 WSC domain Glyco_hydro_18 PF00704.23 KFX88134.1 - 1.4e-17 64.1 0.7 1.3e-16 61.0 0.5 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFX88134.1 - 0.00015 21.6 0.2 0.00036 20.3 0.1 1.7 1 0 0 1 1 1 1 LysM domain DUF4531 PF15041.1 KFX88134.1 - 0.029 14.1 0.2 0.058 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) Glyco_hydro_61 PF03443.9 KFX88137.1 - 5.3e-57 193.1 0.3 8.8e-57 192.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KFX88137.1 - 6.2e-06 25.7 4.4 6.2e-06 25.7 3.1 3.4 3 0 0 3 3 3 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 KFX88137.1 - 0.033 14.2 0.1 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_61 PF03443.9 KFX88138.1 - 3.9e-49 167.4 0.0 4.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFX88138.1 - 0.076 13.0 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Lipase_GDSL PF00657.17 KFX88140.1 - 1.9e-09 37.7 2.2 3.8e-09 36.7 1.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX88140.1 - 1.4e-07 31.8 3.9 4.1e-07 30.3 2.7 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1295 PF06966.7 KFX88141.1 - 3.8e-14 52.5 0.0 6.2e-14 51.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KFX88141.1 - 5.7e-05 21.8 0.1 8.2e-05 21.3 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sugar_tr PF00083.19 KFX88142.1 - 3.2e-106 355.6 20.9 3.6e-106 355.4 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88142.1 - 1.3e-21 76.7 43.6 5.1e-20 71.4 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexokinase_1 PF00349.16 KFX88143.1 - 1e-28 100.0 0.0 1.5e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KFX88143.1 - 7.2e-24 84.3 0.1 4e-16 58.9 0.0 3.1 1 1 1 2 2 2 2 Hexokinase CK_II_beta PF01214.13 KFX88146.1 - 1.1e-76 256.4 0.0 2e-76 255.5 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KFX88146.1 - 0.032 14.8 5.6 0.032 14.8 3.9 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 KFX88146.1 - 0.26 11.6 10.1 1.3 9.4 3.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KFX88146.1 - 4.3 6.8 9.5 0.59 9.6 3.4 1.7 2 0 0 2 2 2 0 Nucleoplasmin Cupin_8 PF13621.1 KFX88147.1 - 4.4e-24 85.3 0.0 6.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Pyr_redox_3 PF13738.1 KFX88147.1 - 5.7e-21 75.5 0.0 1.2e-20 74.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX88147.1 - 1.6e-09 36.4 0.2 7.2e-08 31.0 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX88147.1 - 6.6e-08 32.4 0.1 4.8e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFX88147.1 - 5.2e-07 28.9 0.0 8.3e-06 24.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Cupin_2 PF07883.6 KFX88147.1 - 7.1e-05 22.2 0.1 0.00022 20.6 0.0 1.9 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.17 KFX88147.1 - 9.7e-05 22.5 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KFX88147.1 - 0.002 17.4 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_3 PF05899.7 KFX88147.1 - 0.036 13.4 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFX88147.1 - 0.038 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 AraC-like ligand binding domain Shikimate_DH PF01488.15 KFX88147.1 - 0.16 12.0 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DOPA_dioxygen PF08883.6 KFX88148.1 - 8.1e-31 106.1 0.0 1.5e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family adh_short PF00106.20 KFX88150.1 - 4.5e-18 65.7 0.3 7.9e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX88150.1 - 9.1e-12 45.2 0.2 1.8e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX88150.1 - 5.9e-06 26.0 0.1 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX88150.1 - 0.0094 15.9 1.2 0.02 14.8 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFX88150.1 - 0.045 13.5 0.3 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFX88150.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KFX88150.1 - 0.066 12.8 0.3 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX88150.1 - 0.089 12.8 0.2 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sas10 PF09368.5 KFX88151.1 - 8.4e-30 102.7 7.0 3.1e-29 100.9 4.9 2.1 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KFX88151.1 - 4.7e-12 45.9 5.8 5.4e-12 45.7 0.0 3.6 4 0 0 4 4 4 1 Sas10/Utp3/C1D family Rox3 PF08633.5 KFX88152.1 - 5.3e-48 163.9 0.2 5.3e-48 163.9 0.1 2.1 2 0 0 2 2 2 1 Rox3 mediator complex subunit DUF2080 PF09853.4 KFX88152.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) RRM_1 PF00076.17 KFX88153.1 - 1.3e-57 191.3 1.3 5e-18 64.4 0.0 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88153.1 - 5.6e-41 138.3 0.1 4.8e-12 45.6 0.0 5.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88153.1 - 1.6e-25 88.6 3.2 1.9e-08 34.0 0.0 4.9 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.6 KFX88153.1 - 0.011 14.1 11.8 0.02 13.2 8.2 1.4 1 0 0 1 1 1 0 SGT1 protein SET_assoc PF11767.3 KFX88153.1 - 0.019 14.2 0.0 4.6 6.6 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Ribosomal_L1 PF00687.16 KFX88154.1 - 8.2e-51 172.4 0.4 9.9e-51 172.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Myb_DNA-bind_6 PF13921.1 KFX88155.1 - 9.5e-05 22.4 0.2 0.00051 20.0 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX88155.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAM195 PF14799.1 KFX88155.1 - 0.031 14.1 1.6 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 FAM195 family WXG100 PF06013.7 KFX88156.1 - 2e-07 30.8 0.3 2.5e-07 30.6 0.2 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF2388 PF09498.5 KFX88156.1 - 0.036 13.6 0.1 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) CBS PF00571.23 KFX88158.1 - 2.9e-16 58.9 1.4 9.2e-06 25.3 0.0 3.7 4 0 0 4 4 4 3 CBS domain Sugar_tr PF00083.19 KFX88159.1 - 3.3e-118 395.1 30.2 3.9e-118 394.8 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88159.1 - 2.7e-19 69.0 39.4 1e-13 50.7 15.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_3_Rpc31 PF11705.3 KFX88163.1 - 1.1e-48 166.2 3.2 1.2e-48 166.0 2.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 KFX88163.1 - 0.033 14.0 1.4 0.031 14.1 1.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 KFX88163.1 - 0.12 11.4 5.3 0.15 11.1 3.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 KFX88163.1 - 5.1 5.7 13.0 6.8 5.3 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.14 KFX88163.1 - 5.1 7.5 10.1 11 6.5 7.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein MSC PF09402.5 KFX88166.1 - 1.2e-47 162.3 0.0 1.3e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain UPF0449 PF15136.1 KFX88166.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 tRNA-synt_1b PF00579.20 KFX88167.1 - 2e-54 184.6 0.0 2.8e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3455 PF11937.3 KFX88170.1 - 8e-34 117.1 0.0 1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) TPR_11 PF13414.1 KFX88171.1 - 4.8e-51 170.2 41.7 1.5e-13 50.1 0.5 7.3 3 3 5 9 9 9 8 TPR repeat TPR_1 PF00515.23 KFX88171.1 - 1.1e-40 135.5 24.4 1.7e-05 24.2 0.0 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFX88171.1 - 1.2e-38 127.9 24.7 0.00027 20.6 0.1 11.0 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 KFX88171.1 - 2.5e-26 91.7 10.8 3.9e-06 27.3 0.4 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFX88171.1 - 3.3e-24 84.6 23.8 9.5e-07 28.6 0.5 7.4 3 1 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 KFX88171.1 - 5.7e-17 60.4 11.0 0.072 13.3 0.0 9.0 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFX88171.1 - 5.5e-15 53.9 15.4 0.049 13.4 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFX88171.1 - 9e-15 53.2 12.0 0.11 12.3 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFX88171.1 - 7.8e-14 51.7 16.1 1.3e-06 28.5 0.6 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KFX88171.1 - 2.2e-12 46.9 17.4 0.00033 20.7 0.3 5.5 3 2 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFX88171.1 - 2.7e-12 46.1 16.0 0.088 13.4 0.2 8.3 7 3 2 9 9 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFX88171.1 - 3e-12 46.2 13.7 0.00017 21.3 0.3 6.1 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFX88171.1 - 3.9e-07 29.3 6.3 0.053 12.5 0.8 4.7 2 2 1 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.2 KFX88171.1 - 0.00079 19.2 6.7 3.1 7.6 0.0 5.2 3 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 KFX88171.1 - 0.0032 17.3 14.4 0.36 10.8 0.3 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFX88171.1 - 0.0046 16.1 15.8 1 8.6 0.0 7.0 8 0 0 8 8 8 1 SHNi-TPR BLVR PF06375.6 KFX88171.1 - 0.0049 16.7 1.3 0.0091 15.8 0.9 1.4 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Sel1 PF08238.7 KFX88171.1 - 0.089 13.4 7.8 0.75 10.5 0.1 4.5 4 0 0 4 4 4 0 Sel1 repeat TPR_6 PF13174.1 KFX88171.1 - 0.4 11.2 24.0 6.5 7.4 0.3 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat Btz PF09405.5 KFX88172.1 - 1e-27 96.7 1.5 1e-27 96.7 1.0 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 KFX88173.1 - 5.4e-20 70.6 54.1 5e-07 29.1 5.0 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type zf-DHHC PF01529.15 KFX88173.1 - 0.0027 17.1 0.1 0.0027 17.1 0.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase GNVR PF13807.1 KFX88173.1 - 0.14 11.9 0.5 0.36 10.6 0.3 1.7 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase NmrA PF05368.8 KFX88174.1 - 1e-19 70.7 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX88174.1 - 1.2e-15 58.0 0.0 2.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFX88174.1 - 3.2e-07 29.6 0.0 5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFX88174.1 - 0.00029 20.9 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFX88174.1 - 0.0049 16.8 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.10 KFX88174.1 - 0.0094 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 KFX88174.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ThiF PF00899.16 KFX88174.1 - 0.097 12.4 0.3 3.9 7.3 0.1 2.5 1 1 1 2 2 2 0 ThiF family MBF1 PF08523.5 KFX88175.1 - 4.6e-26 90.6 1.4 8.1e-26 89.8 1.0 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KFX88175.1 - 6.2e-09 35.5 0.0 9.4e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFX88175.1 - 0.00078 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFX88175.1 - 0.0095 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.4 KFX88175.1 - 0.067 12.8 0.1 0.078 12.5 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF3614 PF12267.3 KFX88182.1 - 0.82 9.9 4.5 1.2 9.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) OAD_gamma PF04277.8 KFX88182.1 - 3.6 8.0 8.2 13 6.2 0.5 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Arrestin_N PF00339.24 KFX88185.1 - 8.5e-11 41.8 0.9 1.3e-06 28.3 0.0 3.1 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFX88185.1 - 4.8e-08 33.2 0.0 2.8e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain PTCB-BRCT PF12738.2 KFX88186.1 - 8.1e-49 163.3 0.8 2.3e-21 75.4 0.0 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KFX88186.1 - 2.1e-33 114.2 1.9 1.5e-13 50.6 0.0 5.4 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain LSM PF01423.17 KFX88190.1 - 4.3e-12 45.3 0.0 4.4e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFX88190.1 - 0.0012 18.7 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain HlyD_3 PF13437.1 KFX88190.1 - 0.0083 16.4 0.0 0.0088 16.3 0.0 1.0 1 0 0 1 1 1 1 HlyD family secretion protein BPL_C PF02237.12 KFX88190.1 - 0.053 13.2 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF3247 PF11607.3 KFX88190.1 - 0.067 13.4 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Snf7 PF03357.16 KFX88194.1 - 0.00026 20.4 0.2 0.00034 20.0 0.0 1.2 1 1 0 1 1 1 1 Snf7 DSHCT PF08148.7 KFX88195.1 - 4.9e-60 201.8 0.6 9.3e-60 200.9 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 KFX88195.1 - 0.0013 17.9 0.1 0.0082 15.3 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain Ras PF00071.17 KFX88198.1 - 1.8e-58 196.4 0.2 2.2e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX88198.1 - 9.3e-18 64.8 0.0 1.3e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX88198.1 - 2.5e-07 30.0 0.0 2.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX88198.1 - 1.8e-06 27.4 0.1 7.6e-06 25.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX88198.1 - 0.0052 16.7 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX88198.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 KFX88198.1 - 0.093 11.9 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 KFX88198.1 - 0.1 11.7 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KFX88198.1 - 0.11 11.9 0.6 1 8.7 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein NAD_binding_1 PF00175.16 KFX88201.1 - 8.7e-15 55.2 0.0 1.5e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFX88201.1 - 9.3e-06 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KFX88201.1 - 0.00047 20.2 0.0 0.00089 19.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PEMT PF04191.8 KFX88202.1 - 1.2e-57 192.4 11.8 4.6e-36 123.1 1.6 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase ParA PF10609.4 KFX88203.1 - 4.7e-35 119.3 0.0 1e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFX88203.1 - 1.6e-16 60.3 0.0 2.4e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFX88203.1 - 2.3e-05 24.3 0.0 5.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KFX88203.1 - 0.00014 21.0 0.0 0.0028 16.7 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KFX88203.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KFX88203.1 - 0.0019 17.8 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX88203.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX88203.1 - 0.015 14.6 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFX88203.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX88203.1 - 0.022 14.4 1.1 0.5 10.1 0.1 2.5 2 1 0 2 2 2 0 Part of AAA domain Fer4_NifH PF00142.13 KFX88203.1 - 0.044 12.9 0.0 0.7 9.0 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 KFX88203.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFX88203.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KFX88203.1 - 0.086 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KFX88203.1 - 0.092 12.7 0.0 0.22 11.4 0.1 1.5 2 0 0 2 2 1 0 AAA ATPase domain Zn_Tnp_IS1595 PF12760.2 KFX88203.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_5 PF07728.9 KFX88203.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Med3 PF11593.3 KFX88206.1 - 3.4 6.8 8.4 4.3 6.4 5.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LAMTOR PF15454.1 KFX88207.1 - 3.3e-16 59.3 0.9 4.8e-16 58.8 0.6 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Peptidase_M41 PF01434.13 KFX88222.1 - 5.9e-75 251.3 0.0 9.9e-75 250.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFX88222.1 - 4.3e-42 143.4 0.0 9.9e-42 142.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APH PF01636.18 KFX88222.1 - 5.5e-09 36.1 0.0 2.4e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family FtsH_ext PF06480.10 KFX88222.1 - 4.6e-06 26.7 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KFX88222.1 - 0.00021 21.0 0.0 0.00055 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX88222.1 - 0.0018 18.4 0.1 0.37 10.9 0.1 3.0 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KFX88222.1 - 0.0053 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFX88222.1 - 0.007 16.1 0.8 0.037 13.7 0.5 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KFX88222.1 - 0.01 16.6 0.0 0.035 14.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFX88222.1 - 0.012 14.3 0.1 0.021 13.5 0.1 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 KFX88222.1 - 0.022 14.7 0.2 0.24 11.3 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KFX88222.1 - 0.026 13.6 0.3 0.07 12.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_2 PF07724.9 KFX88222.1 - 0.028 14.3 0.0 0.097 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KFX88222.1 - 0.062 12.7 0.3 0.18 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFX88222.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFX88222.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-C2H2_6 PF13912.1 KFX88236.1 - 0.0027 17.5 0.2 0.0096 15.7 0.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger SNF2_N PF00176.18 KFX88237.1 - 7.9e-44 149.6 0.0 1.3e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KFX88237.1 - 5.6e-05 22.7 0.0 0.00022 20.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFX88237.1 - 0.00026 20.8 0.0 0.0007 19.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ssu72 PF04722.8 KFX88237.1 - 0.039 13.2 0.3 0.081 12.2 0.2 1.5 1 0 0 1 1 1 0 Ssu72-like protein DUF3944 PF13099.1 KFX88237.1 - 0.29 10.6 1.3 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) PS_Dcarbxylase PF02666.10 KFX88241.1 - 1.6e-51 174.5 0.0 3.2e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KFX88241.1 - 7.7e-34 115.3 0.1 7.5e-17 60.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KFX88241.1 - 1.4e-05 25.1 0.2 8.9e-05 22.5 0.1 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFX88241.1 - 0.0036 16.4 0.0 0.02 14.1 0.0 2.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX88241.1 - 0.0069 16.1 0.0 0.073 12.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain CEP76-C2 PF15627.1 KFX88241.1 - 0.095 12.2 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 CEP76 C2 domain Ank_2 PF12796.2 KFX88244.1 - 1.5e-36 124.5 8.7 1.6e-10 41.1 0.0 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Sdh5 PF03937.11 KFX88244.1 - 7.6e-23 79.9 0.1 2.3e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Ank PF00023.25 KFX88244.1 - 5.2e-19 67.0 10.3 0.0004 20.0 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 KFX88244.1 - 1.1e-14 54.4 3.6 1.7e-05 25.1 0.0 7.0 3 1 5 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX88244.1 - 1.7e-14 52.4 7.7 0.0031 17.6 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KFX88244.1 - 2.5e-14 52.9 6.1 0.0019 18.4 0.0 6.7 4 3 3 7 7 6 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 KFX88244.1 - 4.4e-07 30.0 0.0 2.1e-06 27.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KFX88244.1 - 1.6e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX88244.1 - 3.7e-05 23.8 0.0 0.00022 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFX88244.1 - 0.16 12.1 0.2 0.64 10.2 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Shigella_OspC PF06128.6 KFX88244.1 - 0.22 10.9 0.0 4.9 6.5 0.0 2.3 1 1 1 2 2 2 0 Shigella flexneri OspC protein Pribosyltran PF00156.22 KFX88251.1 - 9.1e-13 48.0 0.4 3e-12 46.3 0.1 2.0 2 1 1 3 3 3 1 Phosphoribosyl transferase domain DUF1680 PF07944.7 KFX88252.1 - 5e-140 467.2 1.2 5.7e-140 467.0 0.9 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) MFS_1 PF07690.11 KFX88253.1 - 9.4e-44 149.5 47.8 1.6e-43 148.8 33.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily 4HBT_2 PF13279.1 KFX88256.1 - 8e-07 29.5 0.1 1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Radical_SAM PF04055.16 KFX88257.1 - 8.3e-24 84.6 0.2 2.2e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 KFX88257.1 - 4e-23 81.2 0.0 1.3e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 KFX88257.1 - 3.5e-09 36.7 0.6 1.6e-08 34.6 0.4 2.1 1 1 0 1 1 1 1 Flavodoxin DTHCT PF08070.6 KFX88257.1 - 2 9.0 10.7 0.45 11.1 3.5 2.3 2 0 0 2 2 2 0 DTHCT (NUC029) region AA_permease_2 PF13520.1 KFX88259.1 - 3.1e-47 161.0 53.0 3.9e-47 160.7 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX88259.1 - 1.6e-24 86.1 44.9 2.2e-24 85.6 31.1 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KFX88260.1 - 3.7e-16 58.7 52.5 1e-10 40.9 16.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily adh_short PF00106.20 KFX88261.1 - 9.1e-19 67.9 1.6 1.5e-18 67.2 1.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX88261.1 - 1.2e-08 34.8 0.6 1.7e-08 34.3 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX88261.1 - 1.7e-08 34.5 0.1 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX88261.1 - 0.0002 20.9 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX88261.1 - 0.0041 17.1 0.3 0.012 15.6 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding RrnaAD PF00398.15 KFX88262.1 - 7.7e-58 195.5 0.0 1e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFX88262.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX88262.1 - 3e-07 31.0 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX88262.1 - 9e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFX88262.1 - 0.0001 21.9 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFX88262.1 - 0.00026 20.1 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KFX88262.1 - 0.00046 20.6 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFX88262.1 - 0.00055 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 KFX88262.1 - 0.001 18.6 0.1 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 KFX88262.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX88262.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX88262.1 - 0.01 16.2 0.0 0.031 14.7 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain UPF0020 PF01170.13 KFX88262.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 KFX88262.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRP1_N PF06424.7 KFX88263.1 - 4.2e-17 62.7 0.5 5.2e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal ABA_WDS PF02496.11 KFX88263.1 - 0.068 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 ABA/WDS induced protein DUF1471 PF07338.8 KFX88263.1 - 0.092 12.3 0.9 0.15 11.6 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Ribosomal_60s PF00428.14 KFX88263.1 - 0.4 11.0 4.8 0.63 10.4 3.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein HS1_rep PF02218.10 KFX88280.1 - 0.053 13.4 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Repeat in HS1/Cortactin Peptidase_M28 PF04389.12 KFX88283.1 - 8.8e-34 116.7 0.0 2.2e-33 115.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFX88283.1 - 5.7e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Chalcone PF02431.10 KFX88284.1 - 2e-58 197.0 0.0 2.7e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 KFX88285.1 - 2.1e-20 72.4 0.0 3.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KFX88285.1 - 0.00067 19.4 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 KFX88285.1 - 0.0017 18.5 0.3 0.008 16.3 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 KFX88285.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 KFX88285.1 - 0.038 13.5 0.2 0.77 9.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_3 PF13417.1 KFX88285.1 - 0.05 13.8 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.15 KFX88285.1 - 0.052 13.2 0.1 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 KFX88285.1 - 0.076 13.0 1.5 3.6 7.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.1 KFX88285.1 - 0.087 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_L13 PF00572.13 KFX88286.1 - 4.5e-27 94.6 0.0 8.8e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 KFX88286.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AMP-binding PF00501.23 KFX88287.1 - 3.4e-69 233.2 0.1 4.2e-69 232.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX88287.1 - 1.2e-16 61.3 0.0 2.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 KFX88287.1 - 0.036 13.1 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain F-box-like PF12937.2 KFX88288.1 - 7.7e-11 41.5 0.4 2.8e-10 39.7 0.3 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KFX88288.1 - 8.7e-09 34.5 14.7 6.6 7.1 0.0 10.7 12 0 0 12 12 12 3 Leucine Rich repeat LRR_4 PF12799.2 KFX88288.1 - 3.6e-07 29.6 10.6 2 8.1 0.0 7.2 7 1 0 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.28 KFX88288.1 - 4.1e-06 26.3 0.0 0.00013 21.4 0.0 2.8 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KFX88288.1 - 0.43 10.8 29.8 17 5.8 0.1 9.7 8 3 1 9 9 9 0 Leucine Rich Repeat PMI_typeI PF01238.16 KFX88290.1 - 1.9e-141 471.4 0.0 2.2e-141 471.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Hexapep PF00132.19 KFX88291.1 - 1.3e-07 30.8 9.2 8.8e-05 21.8 0.3 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX88291.1 - 2.6e-05 23.6 11.0 0.00045 19.7 0.4 4.1 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KFX88291.1 - 0.15 10.5 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Asp_Glu_race PF01177.17 KFX88292.1 - 1.1e-20 74.5 0.1 1.4e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.14 KFX88293.1 - 3.3e-116 387.9 0.0 4.1e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFX88293.1 - 0.0036 15.9 0.0 0.012 14.1 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Sugar_tr PF00083.19 KFX88294.1 - 2e-83 280.4 26.5 8.1e-82 275.1 18.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88294.1 - 9.6e-30 103.4 44.6 1.5e-28 99.5 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KFX88295.1 - 6.9e-62 208.9 0.0 9.6e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88295.1 - 1.2e-29 103.1 0.0 2.7e-29 102.0 0.0 1.6 1 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX88295.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFX88295.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_67M PF07488.7 KFX88296.1 - 9.7e-152 504.5 0.1 1.4e-151 503.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KFX88296.1 - 2.6e-94 314.8 4.6 4e-94 314.2 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KFX88296.1 - 2.1e-29 102.0 0.0 3.4e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KFX88296.1 - 0.00035 21.0 0.0 0.00094 19.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 MCM PF00493.18 KFX88298.1 - 4.6e-45 153.8 0.0 5.3e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 MCM2/3/5 family AAA_32 PF13654.1 KFX88298.1 - 0.02 13.5 0.1 0.024 13.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 KFX88299.1 - 1.3e-103 339.5 7.3 4.7e-22 78.1 0.2 7.4 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX88299.1 - 3.4e-93 301.1 11.6 3.8e-07 29.5 0.0 13.6 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.1 KFX88299.1 - 1.9e-75 241.1 5.6 8e-06 25.6 0.0 13.7 13 0 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KFX88299.1 - 1.5e-60 200.6 8.0 9.1e-10 38.7 0.0 10.1 8 2 1 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX88299.1 - 7.1e-56 184.9 24.4 3.4e-07 30.3 0.0 11.3 2 2 10 12 12 12 12 Ankyrin repeats (many copies) NACHT PF05729.7 KFX88299.1 - 1.1e-08 34.8 0.0 2.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFX88299.1 - 1.7e-05 24.9 0.2 6.9e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX88299.1 - 0.014 15.5 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 KFX88300.1 - 1.1e-74 249.4 0.2 1.3e-74 249.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFX88300.1 - 1.9e-13 50.1 0.0 2.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFX88300.1 - 2.9e-12 45.9 2.1 8.5e-09 34.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFX88300.1 - 8.9e-12 44.5 0.1 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX88300.1 - 2.6e-10 39.8 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFX88300.1 - 5.1e-08 33.4 0.0 6.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX88300.1 - 0.00013 21.8 0.1 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KFX88300.1 - 0.024 13.6 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DEAD PF00270.24 KFX88310.1 - 1e-44 152.0 0.2 7.9e-44 149.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX88310.1 - 1.9e-21 75.6 0.0 3.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFX88310.1 - 5.9e-21 73.7 0.1 1.2e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFX88310.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit 2OG-FeII_Oxy_2 PF13532.1 KFX88311.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pro_isomerase PF00160.16 KFX88312.1 - 4.1e-44 150.4 0.1 6.4e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KFX88312.1 - 1.5e-07 30.9 5.4 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFX88312.1 - 1.7e-05 24.3 3.9 0.00076 19.2 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX88312.1 - 0.0019 17.7 1.8 0.0088 15.6 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX88312.1 - 0.054 14.1 6.0 0.26 12.0 2.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX88312.1 - 0.3 11.8 6.1 0.65 10.7 2.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF422 PF04240.7 KFX88314.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) MOZART1 PF12554.3 KFX88314.1 - 0.19 11.2 0.3 0.42 10.1 0.2 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated MFS_1 PF07690.11 KFX88315.1 - 1.3e-20 73.4 25.0 3.2e-15 55.7 16.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribonuclease_3 PF00636.21 KFX88316.1 - 9.5e-07 29.2 0.0 2.9e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFX88316.1 - 1.1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like OB_NTP_bind PF07717.11 KFX88319.1 - 8.3e-28 96.5 0.0 4.3e-27 94.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX88319.1 - 4.1e-27 94.1 0.2 9.6e-27 92.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX88319.1 - 2.1e-12 46.7 0.0 5.6e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KFX88319.1 - 7.7e-10 38.7 0.8 1.6e-09 37.6 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KFX88319.1 - 3.1e-07 30.0 0.1 6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX88319.1 - 7.3e-06 26.1 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFX88319.1 - 0.00011 21.1 0.1 0.00035 19.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 KFX88319.1 - 0.00025 20.6 0.1 0.0029 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX88319.1 - 0.0027 17.4 0.6 0.0089 15.7 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KFX88319.1 - 0.035 13.9 0.4 0.3 10.9 0.3 2.2 1 1 0 1 1 1 0 AAA domain Rib_5-P_isom_A PF06026.9 KFX88319.1 - 0.039 13.2 0.1 0.08 12.2 0.1 1.4 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sigma54_activ_2 PF14532.1 KFX88319.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.17 KFX88319.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cellulase PF00150.13 KFX88320.1 - 2.7e-16 59.5 4.1 3.6e-16 59.1 2.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 KFX88320.1 - 2e-07 30.6 0.7 4.3e-07 29.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.12 KFX88320.1 - 1.6e-06 27.2 0.1 4.9e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KFX88320.1 - 0.0024 17.0 0.2 0.005 15.9 0.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 KFX88320.1 - 0.003 17.9 0.0 0.0083 16.5 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 KFX88320.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 ARID PF01388.16 KFX88323.1 - 2.1e-20 72.3 0.0 2.1e-20 72.3 0.0 2.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain GAF_2 PF13185.1 KFX88327.1 - 1.8e-07 31.7 0.0 2.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KFX88327.1 - 0.00077 19.6 0.1 0.0015 18.6 0.1 1.4 1 1 0 1 1 1 1 GAF domain DLH PF01738.13 KFX88328.1 - 1.2e-24 86.7 0.0 3.9e-24 85.1 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX88328.1 - 1.9e-08 34.2 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX88328.1 - 0.0082 15.3 0.0 0.042 13.0 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family TMEM154 PF15102.1 KFX88329.1 - 0.0036 16.9 2.6 0.011 15.3 1.8 1.8 1 1 0 1 1 1 1 TMEM154 protein family DAP10 PF07213.6 KFX88329.1 - 0.0046 16.6 0.6 0.0097 15.6 0.4 1.5 1 0 0 1 1 1 1 DAP10 membrane protein CcmD PF04995.9 KFX88329.1 - 0.0082 15.8 1.1 0.015 14.9 0.7 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) EphA2_TM PF14575.1 KFX88329.1 - 0.018 15.4 0.6 0.08 13.3 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KFX88329.1 - 0.02 13.1 0.4 0.02 13.1 0.3 1.9 2 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E Lipase_GDSL_2 PF13472.1 KFX88331.1 - 0.00064 19.9 0.0 0.00086 19.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box PF00646.28 KFX88332.1 - 0.06 13.0 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 F-box domain ERG4_ERG24 PF01222.12 KFX88333.1 - 2.6e-167 556.7 6.0 3.1e-167 556.5 4.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KFX88333.1 - 0.00064 19.0 1.1 0.00098 18.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Abhydrolase_6 PF12697.2 KFX88347.1 - 1.1e-15 58.0 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX88347.1 - 1.7e-08 34.2 0.0 3.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX88347.1 - 0.00028 20.6 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family MafB19-deam PF14437.1 KFX88347.1 - 0.039 13.5 0.1 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 MafB19-like deaminase PAP2 PF01569.16 KFX88350.1 - 3.2e-20 72.1 5.5 3.2e-20 72.1 3.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily Ribosomal_L18p PF00861.17 KFX88354.1 - 2.7e-43 146.9 0.1 4.6e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KFX88354.1 - 7.7e-30 103.3 9.9 7.7e-30 103.3 6.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 KFX88355.1 - 8.9e-16 58.6 0.0 3.4e-15 56.7 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX88355.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like GATase PF00117.23 KFX88356.1 - 1.5e-08 34.2 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MoaE PF02391.12 KFX88356.1 - 0.051 13.3 0.4 0.088 12.6 0.3 1.3 1 0 0 1 1 1 0 MoaE protein Sugar_tr PF00083.19 KFX88358.1 - 1.2e-106 357.0 20.5 1.4e-106 356.8 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88358.1 - 3e-32 111.7 43.2 1.2e-29 103.2 14.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KFX88358.1 - 0.00014 20.7 0.6 0.00031 19.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Methyltransf_18 PF12847.2 KFX88359.1 - 1.1e-13 51.7 0.0 1.8e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX88359.1 - 7.4e-13 48.7 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX88359.1 - 1.2e-12 47.6 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX88359.1 - 2.9e-11 43.4 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX88359.1 - 5.9e-11 42.3 0.0 7.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX88359.1 - 5.6e-10 39.5 0.0 8.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX88359.1 - 1.4e-07 30.8 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFX88359.1 - 3.3e-07 30.6 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFX88359.1 - 0.00012 20.8 0.0 0.00017 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 KFX88359.1 - 0.0035 16.4 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 KFX88359.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.9 KFX88359.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase small domain Pox_MCEL PF03291.11 KFX88359.1 - 0.021 13.7 0.0 0.072 11.9 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme PCMT PF01135.14 KFX88359.1 - 0.043 13.3 0.0 0.086 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 KFX88359.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_PK PF05891.7 KFX88359.1 - 0.099 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Peptidase_C2 PF00648.16 KFX88360.1 - 4e-57 193.4 1.1 3.2e-37 128.1 0.2 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease DUF3543 PF12063.3 KFX88363.1 - 4.7e-90 300.9 0.0 7.9e-90 300.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KFX88363.1 - 3.7e-62 209.8 0.0 6.1e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88363.1 - 1.6e-42 145.4 0.0 3.1e-42 144.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX88363.1 - 0.091 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 KFX88364.1 - 2.2e-31 108.8 27.9 2.2e-31 108.8 19.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3405 PF11885.3 KFX88365.1 - 4.8e-131 437.4 0.0 6.1e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Transp_cyt_pur PF02133.10 KFX88366.1 - 2.3e-147 491.1 34.7 2.6e-147 490.9 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Alpha_E2_glycop PF00943.14 KFX88368.1 - 0.0095 14.6 2.3 0.5 8.9 0.1 2.9 2 1 1 4 4 4 2 Alphavirus E2 glycoprotein Zn_clus PF00172.13 KFX88369.1 - 7.8e-08 32.1 14.6 7.8e-08 32.1 10.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX88369.1 - 1.6e-07 30.2 1.3 4.8e-07 28.7 0.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Erf4 PF10256.4 KFX88370.1 - 0.01 15.6 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family CAF-1_p150 PF11600.3 KFX88370.1 - 0.058 12.7 24.9 0.093 12.0 17.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 KFX88370.1 - 3.9 7.2 12.0 6.2 6.6 8.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 KFX88370.1 - 7.8 5.1 15.0 11 4.6 10.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 KFX88370.1 - 8.9 5.6 22.9 16 4.8 15.8 1.4 1 0 0 1 1 1 0 DDRGK domain Glyco_hydro_20 PF00728.17 KFX88371.1 - 3.9e-84 282.8 0.0 4.8e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFX88371.1 - 1.7e-19 70.7 0.0 2.9e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFX88371.1 - 3.2e-05 24.4 0.0 6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_transf_22 PF03901.12 KFX88372.1 - 4.9e-81 272.8 19.8 5.9e-81 272.6 13.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 KFX88373.1 - 2.4e-105 352.1 0.0 3.1e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KFX88373.1 - 1.5e-05 24.2 0.0 2.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFX88373.1 - 0.0002 20.4 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_22 PF13401.1 KFX88373.1 - 0.017 15.2 0.0 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain HSCB_C PF07743.8 KFX88376.1 - 0.12 12.7 0.1 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain zf-TRAF PF02176.13 KFX88377.1 - 2.7e-10 40.4 20.3 4e-05 23.9 1.2 4.0 2 1 2 4 4 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KFX88377.1 - 2.2e-07 30.7 5.8 2.2e-07 30.7 4.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX88377.1 - 2.6e-07 30.2 4.1 2.6e-07 30.2 2.9 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFX88377.1 - 2.8e-07 30.2 5.4 2.8e-07 30.2 3.7 2.8 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX88377.1 - 1.8e-06 27.5 5.2 1.8e-06 27.5 3.6 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX88377.1 - 1.9e-05 24.2 3.7 1.9e-05 24.2 2.6 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX88377.1 - 5.3e-05 23.0 6.9 5.3e-05 23.0 4.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX88377.1 - 0.00025 20.6 3.6 0.00025 20.6 2.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Sina PF03145.11 KFX88377.1 - 0.01 15.4 7.2 0.6 9.7 0.1 2.4 2 1 0 2 2 2 0 Seven in absentia protein family zf-RING_6 PF14835.1 KFX88377.1 - 0.018 14.7 2.2 0.018 14.7 1.5 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFX88377.1 - 0.16 11.5 11.6 1.2 8.7 8.0 2.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C4H2 PF10146.4 KFX88377.1 - 4.6 7.1 11.0 7.8 6.4 0.1 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein FTR1 PF03239.9 KFX88380.1 - 6.4e-82 274.9 6.9 7.8e-82 274.6 4.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Cytochrom_B_N PF00033.14 KFX88380.1 - 0.0007 18.9 0.4 0.0007 18.9 0.3 2.4 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF3169 PF11368.3 KFX88380.1 - 0.026 13.7 0.1 0.026 13.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) GPI2 PF06432.6 KFX88380.1 - 0.42 9.8 3.0 0.97 8.7 0.8 2.2 1 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4231 PF14015.1 KFX88380.1 - 6.6 6.7 6.8 0.67 9.9 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Apolipoprotein PF01442.13 KFX88384.1 - 6.8e-06 25.7 7.4 0.00091 18.7 4.2 3.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4108 PF13390.1 KFX88384.1 - 0.00041 20.0 0.6 0.0016 18.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4108) MHCassoc_trimer PF08831.5 KFX88384.1 - 0.00053 19.7 0.1 0.11 12.3 0.0 3.1 2 1 1 3 3 3 1 Class II MHC-associated invariant chain trimerisation domain Globin PF00042.17 KFX88384.1 - 0.019 15.2 1.2 1.6 9.0 0.1 3.2 2 1 0 3 3 3 0 Globin DUF883 PF05957.8 KFX88384.1 - 0.048 14.0 9.5 3 8.2 0.0 4.7 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Uteroglobin PF01099.12 KFX88384.1 - 0.084 12.6 2.4 0.2 11.4 0.0 2.8 3 0 0 3 3 3 0 Uteroglobin family Spore_III_AB PF09548.5 KFX88384.1 - 0.17 11.5 8.0 3.9 7.2 0.1 3.7 1 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Syntaxin-6_N PF09177.6 KFX88384.1 - 0.39 11.1 4.7 30 5.0 0.1 4.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Peptidase_M41 PF01434.13 KFX88384.1 - 0.43 10.0 6.2 0.26 10.7 0.3 2.8 1 1 0 2 2 2 0 Peptidase family M41 ApoL PF05461.6 KFX88384.1 - 0.84 8.8 7.4 2.2 7.4 0.0 3.3 2 1 0 3 3 3 0 Apolipoprotein L Syntaxin_2 PF14523.1 KFX88384.1 - 1.1 9.2 7.6 2.5 8.2 0.0 3.8 2 1 2 4 4 3 0 Syntaxin-like protein Ish1 PF10281.4 KFX88384.1 - 1.7 8.7 5.0 8.2 6.6 0.1 3.8 3 1 1 4 4 4 0 Putative stress-responsive nuclear envelope protein CENP-T PF15511.1 KFX88386.1 - 1.5 7.9 10.4 1.6 7.8 7.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2201_N PF13203.1 KFX88386.1 - 2.7 7.0 5.3 3.1 6.8 3.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 KFX88386.1 - 7 4.4 21.6 8.7 4.1 15.0 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KFX88386.1 - 8.9 5.2 20.1 10 5.0 13.9 1.1 1 0 0 1 1 1 0 BUD22 Aminotran_4 PF01063.14 KFX88387.1 - 9e-29 100.5 0.0 1.3e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV FGGY_C PF02782.11 KFX88388.1 - 7.4e-27 94.2 0.0 1.4e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFX88388.1 - 6.9e-25 87.7 0.0 4.3e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AhpC-TSA_2 PF13911.1 KFX88390.1 - 5.1e-11 42.5 0.0 7.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFX88390.1 - 4.1e-05 23.2 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFX88390.1 - 0.11 12.0 0.0 0.43 10.1 0.0 1.9 1 1 0 1 1 1 0 Redoxin TFIIB PF00382.14 KFX88392.1 - 1.6e-33 114.2 0.0 7.4e-18 64.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KFX88392.1 - 4.8e-14 51.4 1.4 7.7e-14 50.7 1.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KFX88392.1 - 0.028 14.3 0.0 3 7.7 0.0 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 KFX88392.1 - 0.03 13.6 0.0 0.1 11.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 zf-ribbon_3 PF13248.1 KFX88392.1 - 0.16 11.2 1.1 0.33 10.2 0.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain ATP_sub_h PF10775.4 KFX88393.1 - 6.6e-26 89.8 1.3 9.2e-26 89.3 0.9 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KFX88393.1 - 0.00066 19.5 0.2 0.00083 19.2 0.2 1.3 1 1 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 Cu-oxidase_3 PF07732.10 KFX88397.1 - 9.5e-38 128.5 0.7 2.3e-37 127.3 0.2 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KFX88397.1 - 1.5e-37 128.9 0.6 8.5e-35 119.9 0.2 2.2 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX88397.1 - 0.015 14.7 0.8 0.24 10.9 0.3 2.7 2 1 0 2 2 2 0 Multicopper oxidase Rax2 PF12768.2 KFX88400.1 - 6.3e-95 317.6 2.7 2e-85 286.4 0.0 4.4 4 0 0 4 4 4 3 Cortical protein marker for cell polarity Kelch_3 PF13415.1 KFX88400.1 - 0.00094 19.2 1.7 0.32 11.2 0.2 4.7 4 0 0 4 4 4 1 Galactose oxidase, central domain SNase PF00565.12 KFX88401.1 - 2e-23 82.7 0.2 3e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.9 KFX88402.1 - 7.9e-102 339.6 0.4 9.7e-102 339.3 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 KFX88402.1 - 0.0053 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.16 KFX88402.1 - 0.062 13.4 1.4 4 7.5 0.0 2.6 1 1 0 2 2 2 0 Radical SAM superfamily WD40 PF00400.27 KFX88403.1 - 1.6e-67 221.1 25.4 2.6e-08 33.4 0.1 11.5 12 0 0 12 12 12 10 WD domain, G-beta repeat APH PF01636.18 KFX88403.1 - 2.5e-37 128.8 0.0 5e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Utp12 PF04003.7 KFX88403.1 - 7e-21 74.2 1.5 1.4e-20 73.2 1.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KFX88403.1 - 0.00016 19.9 2.4 0.013 13.7 0.0 3.9 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX88403.1 - 0.00048 19.0 1.5 2.9 6.5 0.1 4.6 2 2 3 5 5 5 2 Nup133 N terminal like EcKinase PF02958.15 KFX88403.1 - 0.0034 16.5 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KFX88403.1 - 0.0045 16.3 0.0 0.048 13.0 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 KFX88403.1 - 0.013 14.5 0.0 0.072 12.0 0.0 2.1 1 1 0 1 1 1 0 Fructosamine kinase eIF2A PF08662.6 KFX88403.1 - 0.065 12.9 0.0 0.85 9.2 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF1679 PF07914.6 KFX88403.1 - 0.071 11.7 0.0 0.22 10.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) ATP-synt_E PF05680.7 KFX88404.1 - 0.055 13.4 0.7 0.055 13.4 0.5 3.3 3 1 0 3 3 3 0 ATP synthase E chain SNARE PF05739.14 KFX88404.1 - 0.16 11.7 6.8 0.035 13.7 1.4 2.4 2 1 0 2 2 2 0 SNARE domain GTP_EFTU PF00009.22 KFX88405.1 - 1.4e-08 34.4 0.0 4.8e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFX88405.1 - 0.19 10.9 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rab5ip PF07019.7 KFX88406.1 - 1e-15 57.6 1.4 1.4e-15 57.1 1.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TauE PF01925.14 KFX88406.1 - 0.035 13.5 2.4 0.044 13.2 1.7 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF3611 PF12263.3 KFX88406.1 - 0.058 12.7 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) BCLP PF12304.3 KFX88406.1 - 0.13 11.6 0.7 3.8 6.8 0.1 2.1 2 0 0 2 2 2 0 Beta-casein like protein Nro1 PF12753.2 KFX88407.1 - 0.056 12.3 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 PCNA_N PF00705.13 KFX88408.1 - 1.9e-54 182.5 3.9 4.5e-54 181.3 2.7 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Vezatin PF12632.2 KFX88408.1 - 1.6e-52 178.1 0.4 2.9e-52 177.2 0.0 1.6 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_C PF02747.10 KFX88408.1 - 4.5e-49 165.6 0.0 9.5e-49 164.5 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KFX88408.1 - 4.8e-09 35.7 0.0 8.9e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KFX88408.1 - 0.0014 17.6 0.1 0.0031 16.5 0.1 1.6 1 1 0 1 1 1 1 Hus1-like protein DUF1480 PF07351.8 KFX88408.1 - 0.086 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Amastin PF07344.6 KFX88408.1 - 0.12 11.9 0.6 0.25 10.9 0.4 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein Spore_permease PF03845.8 KFX88408.1 - 0.45 9.1 0.5 0.7 8.4 0.4 1.1 1 0 0 1 1 1 0 Spore germination protein Phos_pyr_kin PF08543.7 KFX88409.1 - 8.2e-14 51.3 0.0 1.7e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KFX88409.1 - 6.6e-09 35.3 0.6 1.6e-06 27.4 0.0 2.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase dUTPase PF00692.14 KFX88410.1 - 1.6e-42 143.9 0.0 2.1e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 KFX88410.1 - 0.032 12.6 0.0 0.043 12.2 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MARVEL PF01284.18 KFX88411.1 - 2.8e-06 27.2 19.0 3.7e-06 26.8 13.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain Init_tRNA_PT PF04179.7 KFX88412.1 - 8.9e-157 522.5 0.0 1.1e-156 522.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Serglycin PF04360.7 KFX88413.1 - 0.017 14.8 0.2 0.03 14.0 0.1 1.5 1 1 0 1 1 1 0 Serglycin MF_alpha_N PF05436.6 KFX88413.1 - 0.094 12.4 0.4 0.26 11.0 0.3 1.8 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus AF-4 PF05110.8 KFX88413.1 - 1.1 7.0 7.7 1.2 6.9 5.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Fer4_3 PF12798.2 KFX88413.1 - 6.1 7.6 9.3 2.5 8.8 0.1 3.1 2 1 1 3 3 3 0 4Fe-4S binding domain Aldolase_II PF00596.16 KFX88414.1 - 2e-41 141.6 0.0 2.4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 KFX88415.1 - 3.1e-160 532.8 18.5 3.1e-160 532.8 12.8 1.4 2 0 0 2 2 2 1 Calreticulin family adh_short_C2 PF13561.1 KFX88418.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1423 PF07227.6 KFX88419.1 - 0.76 8.3 5.6 1.2 7.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Acyl-CoA_dh_1 PF00441.19 KFX88420.1 - 2.4e-35 121.8 0.1 3.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX88420.1 - 1.4e-16 59.7 0.1 6.9e-16 57.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX88420.1 - 9.8e-13 48.5 0.0 1.8e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX88420.1 - 1.1e-10 42.0 0.0 6.9e-10 39.4 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CFEM PF05730.6 KFX88420.1 - 5.5e-09 35.7 9.9 1e-08 34.8 6.9 1.4 1 0 0 1 1 1 1 CFEM domain Herpes_gE PF02480.11 KFX88420.1 - 0.0012 17.2 0.0 0.0024 16.2 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E HpaB_N PF11794.3 KFX88420.1 - 0.0027 17.1 0.2 0.0062 15.9 0.2 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Plasmodium_Vir PF05795.6 KFX88420.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.4 KFX88420.1 - 1.2 7.2 36.0 1.7 6.8 25.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_pol_B PF00136.16 KFX88422.1 - 3.4e-146 487.6 3.1 5e-146 487.1 2.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KFX88422.1 - 1.9e-80 270.1 0.3 4.2e-80 269.0 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFX88422.1 - 1.4e-22 79.4 6.4 4.3e-22 77.9 4.4 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KFX88422.1 - 0.00019 21.2 0.3 0.0012 18.6 0.2 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KFX88422.1 - 0.0003 20.3 0.1 0.00059 19.4 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 KFX88422.1 - 0.095 12.4 10.6 0.13 11.9 0.8 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rhomboid PF01694.17 KFX88423.1 - 6e-35 120.4 11.8 6e-35 120.4 8.2 2.1 2 0 0 2 2 2 1 Rhomboid family DUF1426 PF07234.6 KFX88423.1 - 1.1 9.0 2.7 19 5.0 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) DUF1479 PF07350.7 KFX88426.1 - 7e-49 166.4 0.1 7.9e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_28 PF03033.15 KFX88427.1 - 8.9e-19 67.6 0.0 3.7e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX88427.1 - 5.7e-06 25.1 0.0 9.9e-06 24.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFX88427.1 - 0.00066 19.3 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Cortex-I_coil PF09304.5 KFX88428.1 - 0.00014 21.8 26.7 0.019 14.9 2.1 3.6 2 2 1 3 3 3 2 Cortexillin I, coiled coil Filament PF00038.16 KFX88428.1 - 0.0016 17.9 8.7 0.0016 17.9 6.0 3.4 1 1 2 3 3 3 2 Intermediate filament protein Fib_alpha PF08702.5 KFX88428.1 - 0.003 17.7 6.5 0.003 17.7 4.5 3.5 3 1 0 3 3 3 1 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.3 KFX88428.1 - 0.0037 16.9 4.5 0.0037 16.9 3.1 4.3 1 1 3 4 4 4 1 TATA element modulatory factor 1 TATA binding Tropomyosin PF00261.15 KFX88428.1 - 0.0056 15.8 5.9 0.0056 15.8 4.1 4.1 1 1 3 4 4 4 2 Tropomyosin TEX12 PF15219.1 KFX88428.1 - 0.046 13.6 0.6 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 Testis-expressed 12 WEMBL PF05701.6 KFX88428.1 - 0.18 10.2 40.0 0.063 11.7 21.7 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KFX88428.1 - 0.31 10.1 2.8 3.3 6.7 0.7 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFX88428.1 - 1 9.1 13.4 1.7 8.4 1.6 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) IncA PF04156.9 KFX88428.1 - 1.3 8.5 36.4 0.069 12.7 12.0 3.4 1 1 1 2 2 1 0 IncA protein ADIP PF11559.3 KFX88428.1 - 1.4 8.7 40.6 1.3 8.8 3.1 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding TMA7 PF09072.5 KFX88428.1 - 1.8 9.0 9.5 16 6.0 0.7 3.2 2 0 0 2 2 2 0 Translation machinery associated TMA7 NPV_P10 PF05531.7 KFX88428.1 - 6.9 6.9 7.0 62 3.9 0.2 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Fork_head PF00250.13 KFX88429.1 - 3.1e-21 75.2 0.1 6.5e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KFX88429.1 - 0.0006 19.8 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.21 KFX88430.1 - 1.2e-08 34.8 17.5 0.002 18.3 0.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX88430.1 - 4.6e-06 26.5 13.3 0.14 12.5 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFX88430.1 - 0.034 14.3 10.1 0.3 11.3 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type GATA PF00320.22 KFX88430.1 - 0.78 9.1 5.3 3.9 6.9 0.1 2.6 2 0 0 2 2 2 0 GATA zinc finger zf-C2H2_jaz PF12171.3 KFX88430.1 - 0.86 9.8 14.1 6.8 6.9 0.7 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFX88430.1 - 5.1 7.2 12.1 16 5.6 0.1 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) HeLo PF14479.1 KFX88431.1 - 2.1e-40 138.7 1.0 2.1e-40 138.7 0.7 3.4 2 1 1 3 3 3 1 Prion-inhibition and propagation CH PF00307.26 KFX88431.1 - 4e-09 36.4 0.0 7.4e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Pkinase PF00069.20 KFX88431.1 - 3e-06 26.5 0.0 7.3e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88431.1 - 0.00084 18.4 0.1 0.007 15.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase NDUFA12 PF05071.11 KFX88432.1 - 1.2e-11 45.0 0.1 2.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hemopexin PF00045.14 KFX88432.1 - 0.085 12.6 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Hemopexin Pkinase PF00069.20 KFX88433.1 - 4e-75 252.3 0.0 5.5e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88433.1 - 8.4e-39 133.1 0.0 1.2e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KFX88433.1 - 3e-15 56.1 0.2 1.1e-14 54.3 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KFX88433.1 - 1.5e-06 27.3 0.0 2.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFX88433.1 - 8.6e-05 21.9 0.4 0.00016 21.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KFX88433.1 - 0.0024 16.5 0.1 0.0047 15.5 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 KFX88433.1 - 0.024 13.6 0.0 0.053 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX88433.1 - 0.11 12.1 0.7 0.69 9.5 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family CytochromB561_N PF09786.4 KFX88433.1 - 0.25 9.7 1.9 0.4 9.0 1.3 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal CFEM PF05730.6 KFX88437.1 - 0.00053 19.7 1.4 0.00053 19.7 0.9 2.2 2 0 0 2 2 2 1 CFEM domain FHA PF00498.21 KFX88439.1 - 1.4e-12 47.5 0.1 3.5e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 FHA domain IFRD PF05004.8 KFX88440.1 - 1.2e-32 113.2 3.6 1.7e-32 112.7 2.5 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 KFX88440.1 - 2.8e-05 24.3 3.3 0.018 15.2 0.3 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KFX88440.1 - 0.098 12.7 0.1 33 4.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat RAP1 PF07218.6 KFX88440.1 - 0.36 8.8 4.4 0.53 8.3 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.13 KFX88440.1 - 0.58 9.0 6.9 0.95 8.3 4.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein IFRD PF05004.8 KFX88441.1 - 0.084 11.9 0.5 0.11 11.5 0.3 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) eIF-5_eIF-2B PF01873.12 KFX88442.1 - 1.6e-45 153.7 0.3 2.4e-45 153.2 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 KFX88442.1 - 0.081 13.2 0.1 0.25 11.6 0.1 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF4604 PF15377.1 KFX88442.1 - 1.7 8.8 20.0 5.1 7.2 13.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) zf-HYPF PF07503.7 KFX88442.1 - 2 7.9 6.7 6.9 6.1 3.1 2.6 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.5 KFX88442.1 - 2.3 8.4 6.7 2.1 8.5 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain Gln-synt_C PF00120.19 KFX88446.1 - 2.4e-61 207.1 0.0 2.9e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFX88446.1 - 4.3e-20 71.0 0.0 6.6e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Fungal_trans PF04082.13 KFX88449.1 - 3.1e-14 52.4 0.1 5.7e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88449.1 - 6.3e-07 29.2 9.7 1.4e-06 28.0 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KFX88450.1 - 2.7e-85 284.8 53.0 7.8e-48 162.4 13.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFX88450.1 - 1.9e-34 118.8 0.2 9.4e-17 61.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KFX88450.1 - 2.6e-28 97.6 0.3 2.9e-25 87.9 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KFX88450.1 - 4.7e-08 32.4 44.9 1.4e-07 30.8 12.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KFX88450.1 - 6.5e-06 25.6 0.2 0.0018 17.7 0.1 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 KFX88450.1 - 2.9e-05 24.2 0.1 0.069 13.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 KFX88450.1 - 7.6e-05 22.2 0.0 0.0089 15.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFX88450.1 - 9.7e-05 21.6 0.0 0.00064 18.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX88450.1 - 0.00045 20.2 0.1 0.056 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFX88450.1 - 0.00048 20.0 0.0 0.68 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KFX88450.1 - 0.0017 18.0 0.0 0.17 11.5 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 KFX88450.1 - 0.0025 18.3 0.2 3.6 8.0 0.0 3.4 3 0 0 3 3 3 1 Miro-like protein AAA PF00004.24 KFX88450.1 - 0.0062 16.7 0.0 2 8.6 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KFX88450.1 - 0.011 15.2 3.0 0.064 12.7 0.2 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFX88450.1 - 0.012 15.0 0.1 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_trans_N PF14510.1 KFX88450.1 - 0.012 15.6 0.1 0.04 13.9 0.1 1.9 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal UPF0079 PF02367.12 KFX88450.1 - 0.018 14.6 1.4 3.3 7.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFX88450.1 - 0.026 14.1 0.3 4.5 6.8 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 KFX88450.1 - 0.034 14.1 0.0 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KFX88450.1 - 0.045 13.7 0.2 0.18 11.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KFX88450.1 - 0.047 13.9 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MIF4G PF02854.14 KFX88451.1 - 1.8e-50 171.2 0.0 2.9e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFX88451.1 - 1.5e-22 79.2 1.2 5.7e-22 77.4 0.8 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA_12 PF13087.1 KFX88452.1 - 9.1e-27 93.7 0.0 1.7e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFX88452.1 - 1.7e-25 90.0 0.0 3e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX88452.1 - 3.4e-10 39.5 0.1 1e-08 34.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFX88452.1 - 5.9e-06 25.9 0.0 0.0044 16.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 KFX88452.1 - 9.7e-05 21.9 0.7 0.0066 15.9 0.0 3.4 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KFX88452.1 - 0.00034 20.5 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KFX88452.1 - 0.00051 19.4 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX88452.1 - 0.002 18.2 0.0 0.0075 16.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFX88452.1 - 0.0021 18.2 0.0 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX88452.1 - 0.0054 16.7 0.0 0.024 14.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 KFX88452.1 - 0.014 14.8 0.0 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase DnaB_C PF03796.10 KFX88452.1 - 0.016 14.1 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 KFX88452.1 - 0.017 14.1 0.8 0.028 13.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KFX88452.1 - 0.022 14.9 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 KFX88452.1 - 0.032 15.0 0.1 0.28 12.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFX88452.1 - 0.04 12.7 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KFX88452.1 - 0.07 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KFX88452.1 - 0.081 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KFX88452.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 KFX88452.1 - 0.25 11.5 0.0 0.68 10.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase efThoc1 PF11957.3 KFX88453.1 - 2.8e-161 537.3 0.5 3.7e-161 536.9 0.0 1.4 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KFX88453.1 - 3.8e-47 160.1 0.0 6.1e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KFX88453.1 - 3.9e-05 23.9 0.0 0.00014 22.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX88453.1 - 0.017 14.3 0.1 0.05 12.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFX88453.1 - 0.034 14.0 0.6 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF313 PF03754.8 KFX88453.1 - 0.092 12.6 0.2 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Pyr_redox_3 PF13738.1 KFX88454.1 - 1.5e-25 90.4 0.1 2.6e-25 89.6 0.0 1.4 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX88454.1 - 2.2e-13 49.2 0.0 2.8e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX88454.1 - 1.7e-09 37.5 0.0 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX88454.1 - 5.7e-07 28.8 0.1 2.1e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KFX88454.1 - 4.3e-05 22.5 0.4 0.00015 20.8 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFX88454.1 - 6.5e-05 21.9 0.1 0.0074 15.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX88454.1 - 0.00079 19.3 0.0 0.003 17.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX88454.1 - 0.0009 19.5 0.1 0.21 12.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX88454.1 - 0.0063 15.4 0.6 0.021 13.7 0.0 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX88454.1 - 0.0087 15.8 2.0 1.3 8.7 0.1 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFX88454.1 - 0.025 13.4 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KFX88454.1 - 0.072 11.9 0.6 0.43 9.3 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KFX88454.1 - 0.17 10.3 0.3 0.35 9.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein p450 PF00067.17 KFX88455.1 - 1.3e-50 172.2 0.0 2e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KFX88456.1 - 3.1e-19 69.2 0.6 6.4e-18 64.9 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KFX88456.1 - 5.7e-09 35.3 0.3 1e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFX88456.1 - 1e-07 31.8 0.1 2.7e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX88456.1 - 2e-07 30.2 1.5 6.5e-07 28.5 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX88456.1 - 1.8e-06 27.9 0.3 1e-05 25.5 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX88456.1 - 8.2e-06 26.1 1.9 7.1e-05 23.1 0.2 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX88456.1 - 2.2e-05 23.4 0.1 2.7e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KFX88456.1 - 3e-05 22.6 0.3 4.3e-05 22.1 0.2 1.4 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KFX88456.1 - 3.2e-05 23.2 0.2 0.0011 18.1 0.1 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KFX88456.1 - 0.00021 20.4 0.1 0.00037 19.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KFX88456.1 - 0.00064 19.3 0.1 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KFX88456.1 - 0.00074 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX88456.1 - 0.00095 18.6 0.0 0.012 15.0 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KFX88456.1 - 0.0021 17.0 0.3 0.029 13.3 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KFX88456.1 - 0.0032 16.8 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 KFX88456.1 - 0.0034 16.5 0.1 0.0065 15.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFX88456.1 - 0.0049 16.5 0.8 0.011 15.3 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFX88456.1 - 0.0051 16.8 0.1 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 KFX88456.1 - 0.0053 15.4 0.5 0.039 12.5 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_10 PF13460.1 KFX88456.1 - 0.0076 16.2 0.2 0.075 13.0 0.1 2.4 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_7 PF13241.1 KFX88456.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DsbD_2 PF13386.1 KFX88458.1 - 0.00056 19.7 0.6 0.00097 18.9 0.4 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region AA_permease_2 PF13520.1 KFX88458.1 - 0.0015 17.1 1.5 0.0018 16.9 1.1 1.0 1 0 0 1 1 1 1 Amino acid permease Vma12 PF11712.3 KFX88458.1 - 0.035 13.8 0.3 0.035 13.8 0.2 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3413 PF11893.3 KFX88458.1 - 9.5 5.0 11.3 17 4.2 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) adh_short PF00106.20 KFX88459.1 - 6.8e-27 94.4 2.4 1.4e-26 93.4 1.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX88459.1 - 8.4e-20 71.5 0.5 1.8e-19 70.4 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX88459.1 - 7.7e-12 45.2 1.8 1.7e-11 44.1 1.2 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFX88459.1 - 0.014 15.1 0.4 0.047 13.4 0.3 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KFX88459.1 - 0.02 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 KFX88459.1 - 0.096 12.5 0.3 0.26 11.0 0.1 1.6 1 1 0 1 1 1 0 ThiF family Fungal_lectin PF07938.7 KFX88464.1 - 5.8e-76 255.7 10.5 6.6e-76 255.5 7.3 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin F-box-like PF12937.2 KFX88465.1 - 0.00026 20.6 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like IMS PF00817.15 KFX88466.1 - 1e-41 142.1 0.0 1.6e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFX88466.1 - 1.7e-12 47.4 0.0 3.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFX88466.1 - 0.004 17.1 0.0 0.0097 15.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF2197 PF09963.4 KFX88466.1 - 0.13 12.2 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) PAT1 PF09770.4 KFX88467.1 - 0.98 7.5 28.8 1.1 7.3 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M22 PF00814.20 KFX88474.1 - 8.3e-45 153.3 0.0 5.2e-41 140.9 0.0 2.5 2 1 0 2 2 2 2 Glycoprotease family WD40 PF00400.27 KFX88474.1 - 1.6e-06 27.7 1.6 0.18 11.7 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat YycC PF14174.1 KFX88474.1 - 0.025 14.2 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein DUF2583 PF10762.4 KFX88474.1 - 0.083 13.0 0.5 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Peptidase_M3 PF01432.15 KFX88475.1 - 9.8e-124 413.8 0.0 2e-123 412.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 KFX88475.1 - 0.066 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DUF2421 PF10334.4 KFX88475.1 - 0.074 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) ApoO PF09769.4 KFX88476.1 - 1.2e-44 151.8 3.3 6.6e-44 149.3 0.0 2.7 2 1 1 3 3 3 2 Apolipoprotein O IU_nuc_hydro PF01156.14 KFX88477.1 - 1.9e-77 260.5 0.0 3.2e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 KFX88477.1 - 2.4e-08 33.5 3.1 5.2e-08 32.3 2.1 1.5 1 0 0 1 1 1 1 RED-like protein N-terminal region UCR_UQCRX_QCR9 PF05365.7 KFX88478.1 - 8.6e-24 82.9 1.6 2.1e-23 81.7 1.1 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 KFX88478.1 - 2e-18 65.8 14.4 4.8e-18 64.6 10.0 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Exo_endo_phos PF03372.18 KFX88478.1 - 1.6e-14 54.4 0.0 2.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ClpS PF02617.12 KFX88478.1 - 8.9e-07 28.5 0.1 2e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Mito_fiss_reg PF05308.6 KFX88478.1 - 0.097 12.0 2.4 0.22 10.8 1.7 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFX88478.1 - 0.1 11.8 4.5 0.19 10.9 3.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mago-bind PF09282.5 KFX88479.1 - 6e-13 48.0 3.2 1.3e-12 47.0 2.2 1.6 1 0 0 1 1 1 1 Mago binding T4SS PF07996.6 KFX88479.1 - 0.015 15.1 3.8 0.023 14.5 2.6 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins RR_TM4-6 PF06459.7 KFX88479.1 - 0.48 10.2 12.0 0.57 10.0 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 KFX88479.1 - 1.7 6.9 3.9 2.1 6.6 2.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.27 KFX88480.1 - 5.6e-65 213.0 22.2 9.6e-13 47.4 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KFX88480.1 - 1.5e-09 37.8 0.1 0.046 13.4 0.0 4.2 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX88480.1 - 8.8e-07 27.4 1.7 0.24 9.4 0.0 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 KFX88480.1 - 1.4e-06 27.4 1.0 0.31 9.9 0.1 4.2 2 1 2 4 4 4 3 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 KFX88480.1 - 0.00041 19.2 1.0 0.56 8.8 0.0 4.2 2 2 1 4 4 4 1 Nup133 N terminal like PD40 PF07676.7 KFX88480.1 - 0.026 14.1 0.9 2.6 7.8 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KFX88480.1 - 0.11 10.6 0.0 0.3 9.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Sld5 PF05916.6 KFX88481.1 - 6.6e-07 29.5 0.1 1e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Ppx-GppA PF02541.11 KFX88483.1 - 4e-41 141.0 0.0 5.3e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family CwfJ_C_1 PF04677.10 KFX88484.1 - 9.6e-27 93.0 0.0 1.8e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KFX88484.1 - 7.1e-24 84.1 0.4 2e-23 82.7 0.1 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 KFX88485.1 - 2e-42 143.9 0.1 6.6e-42 142.2 0.1 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KFX88485.1 - 0.019 15.0 0.6 2.4 8.4 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.18 KFX88485.1 - 0.022 14.6 2.1 23 5.0 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat zf-DNL PF05180.7 KFX88486.1 - 1.6e-29 101.3 0.6 2.3e-29 100.8 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KFX88486.1 - 0.042 13.3 0.2 0.08 12.4 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.8 KFX88486.1 - 0.075 12.7 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 KFX88486.1 - 0.32 10.7 2.7 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFX88486.1 - 0.5 10.0 2.9 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Cullin PF00888.17 KFX88487.1 - 4e-126 421.9 1.9 4e-126 421.9 1.3 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KFX88487.1 - 2.8e-27 94.3 2.4 7e-27 93.0 1.7 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain MFS_1 PF07690.11 KFX88488.1 - 1.2e-29 103.1 28.6 1.2e-29 103.1 19.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 KFX88488.1 - 8.2e-24 84.3 3.2 2.3e-23 82.9 2.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX88488.1 - 1.5e-11 44.5 0.2 2.4e-11 43.8 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX88488.1 - 1.3e-09 38.0 4.8 1.5e-08 34.4 3.3 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX88488.1 - 3.2e-06 27.2 0.2 6.8e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX88488.1 - 1.2e-05 24.9 0.1 2.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX88488.1 - 0.00018 20.3 0.1 0.0003 19.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFX88488.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 KFX88488.1 - 0.025 13.8 0.2 0.047 12.9 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 KFX88488.1 - 0.042 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain DUF2530 PF10745.4 KFX88488.1 - 0.05 13.5 0.9 0.31 11.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) 2-Hacid_dh_C PF02826.14 KFX88488.1 - 0.073 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aa_trans PF01490.13 KFX88492.1 - 1.4e-71 241.1 26.0 1.8e-71 240.7 18.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tcp11 PF05794.8 KFX88493.1 - 2.8e-52 177.9 0.1 4.5e-49 167.3 0.1 2.2 2 0 0 2 2 2 2 T-complex protein 11 zf-RING_2 PF13639.1 KFX88494.1 - 9.8e-07 28.5 4.1 9.8e-07 28.5 2.9 1.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.1 KFX88494.1 - 0.00046 19.8 2.0 0.00046 19.8 1.4 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 SWIM PF04434.12 KFX88494.1 - 0.0046 16.4 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger SART-1 PF03343.8 KFX88494.1 - 0.012 13.9 6.3 0.018 13.4 4.4 1.1 1 0 0 1 1 1 0 SART-1 family zf-rbx1 PF12678.2 KFX88494.1 - 0.017 15.1 2.6 0.017 15.1 1.8 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX88494.1 - 0.56 10.2 6.5 1.4 9.0 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHF5 PF03660.9 KFX88494.1 - 0.67 10.0 7.3 0.058 13.4 1.7 1.7 2 0 0 2 2 2 0 PHF5-like protein C1_1 PF00130.17 KFX88494.1 - 1.3 8.7 7.3 0.55 10.0 2.0 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 KFX88494.1 - 1.7 8.4 10.8 0.15 11.8 3.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain SCRL PF06876.7 KFX88494.1 - 7.7 6.5 10.3 1 9.3 2.2 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-C3HC4 PF00097.20 KFX88494.1 - 8.1 6.2 8.8 0.3 10.7 1.5 2.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFX88494.1 - 9.3 6.2 8.9 0.84 9.6 2.8 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain Peptidase_S10 PF00450.17 KFX88495.1 - 4.4e-80 269.8 0.0 8.6e-80 268.9 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFX88495.1 - 1.2e-07 31.8 0.0 4.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family CDC45 PF02724.9 KFX88496.1 - 6.3 4.7 13.7 0.014 13.4 2.6 1.6 2 0 0 2 2 2 0 CDC45-like protein Scm3 PF10384.4 KFX88497.1 - 0.11 11.9 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 SNF2_N PF00176.18 KFX88499.1 - 1.2e-27 96.5 0.0 2.1e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX88499.1 - 1.4e-07 31.2 0.0 3.4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX88499.1 - 0.019 14.4 0.1 0.07 12.6 0.1 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase Filament PF00038.16 KFX88501.1 - 0.0035 16.8 121.4 0.029 13.8 12.8 6.3 2 2 3 5 5 5 4 Intermediate filament protein EFG_II PF14492.1 KFX88501.1 - 0.017 14.9 1.0 0.08 12.8 0.7 2.2 1 0 0 1 1 1 0 Elongation Factor G, domain II Osmo_CC PF08946.5 KFX88501.1 - 0.11 12.5 14.9 0.096 12.7 1.0 5.3 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Glyco_hydro_2_C PF02836.12 KFX88503.1 - 5.9e-81 271.6 0.1 1.1e-80 270.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KFX88503.1 - 1.7e-36 125.2 0.6 3e-36 124.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX88503.1 - 8.1e-12 45.5 0.2 2.1e-11 44.2 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_53 PF07745.8 KFX88503.1 - 0.01 14.6 0.1 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 DUF4434 PF14488.1 KFX88503.1 - 0.025 14.3 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Acyl_transf_3 PF01757.17 KFX88505.1 - 2.3e-27 95.7 25.9 2.3e-27 95.7 18.0 2.1 2 0 0 2 2 2 1 Acyltransferase family Vma12 PF11712.3 KFX88512.1 - 2.5 7.7 4.3 3.8 7.2 1.2 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2638 PF10937.3 KFX88516.1 - 3.3e-37 127.9 0.6 3.9e-37 127.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Med18 PF09637.5 KFX88517.1 - 2.8e-25 89.2 0.0 3.2e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Med18 protein AAA_16 PF13191.1 KFX88517.1 - 0.05 13.5 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ING PF12998.2 KFX88519.1 - 0.0011 19.2 0.4 0.0041 17.3 0.3 2.1 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1117 PF06547.7 KFX88519.1 - 0.026 14.6 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DUF4404 PF14357.1 KFX88519.1 - 0.4 11.1 2.7 0.49 10.8 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DTHCT PF08070.6 KFX88519.1 - 1.4 9.6 14.9 8.3 7.1 5.8 2.7 2 1 0 2 2 2 0 DTHCT (NUC029) region Acyl-CoA_dh_2 PF08028.6 KFX88521.1 - 0.043 14.0 5.4 0.68 10.1 0.1 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ThiF PF00899.16 KFX88522.1 - 8.8e-16 57.9 0.1 1.6e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 ThiF family DUF2431 PF10354.4 KFX88523.1 - 4.8e-56 189.2 0.0 6.7e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Ank_2 PF12796.2 KFX88524.1 - 1.9e-36 124.2 0.1 7.9e-16 58.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX88524.1 - 4e-25 87.7 0.1 5.8e-08 33.0 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KFX88524.1 - 1.3e-23 81.5 2.6 0.00012 21.7 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KFX88524.1 - 5.8e-21 74.0 0.1 3.5e-06 27.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX88524.1 - 1.9e-17 61.5 0.0 0.019 15.1 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.7 KFX88524.1 - 9.4e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX88524.1 - 0.00018 21.6 0.0 0.00083 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KFX88524.1 - 0.063 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KFX88524.1 - 0.087 13.6 0.1 3.1 8.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain BRE1 PF08647.6 KFX88525.1 - 3.7e-25 87.7 5.0 3.7e-25 87.7 3.5 6.4 5 1 2 7 7 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KFX88525.1 - 5.7e-08 32.6 10.5 9.6e-08 31.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX88525.1 - 1.9e-07 30.6 8.9 3.2e-07 29.9 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX88525.1 - 2.1e-07 30.4 11.7 3.7e-07 29.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX88525.1 - 5.8e-06 25.9 11.6 9.5e-06 25.2 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFX88525.1 - 8.6e-06 25.4 8.5 1.4e-05 24.7 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFX88525.1 - 0.00039 20.0 6.9 0.00093 18.8 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 KFX88525.1 - 0.0053 15.9 4.0 0.0053 15.9 2.8 4.9 2 2 2 5 5 5 2 Reovirus sigma C capsid protein zf-rbx1 PF12678.2 KFX88525.1 - 0.024 14.7 7.0 0.08 13.0 4.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KFX88525.1 - 0.03 13.8 2.2 0.061 12.8 1.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 KFX88525.1 - 0.031 14.1 8.3 0.06 13.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2H2 PF00096.21 KFX88525.1 - 0.034 14.4 1.3 2.3 8.7 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.1 KFX88525.1 - 0.042 13.4 7.3 0.13 11.8 5.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFX88525.1 - 0.084 12.7 7.1 0.16 11.8 4.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFX88525.1 - 0.12 12.1 1.8 0.26 11.0 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DinB_2 PF12867.2 KFX88525.1 - 0.18 12.1 5.7 0.27 11.5 1.7 2.9 2 1 0 2 2 2 0 DinB superfamily GAS PF13851.1 KFX88525.1 - 1.2 8.2 75.3 0.85 8.7 7.5 5.9 4 2 0 5 5 5 0 Growth-arrest specific micro-tubule binding FYVE PF01363.16 KFX88525.1 - 1.3 8.9 11.5 19 5.2 8.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-H2C2_2 PF13465.1 KFX88525.1 - 1.8 8.9 6.0 8.2 6.9 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-FCS PF06467.9 KFX88525.1 - 1.9 8.2 6.7 37 4.0 2.9 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HLH PF00010.21 KFX88527.1 - 2.1e-12 46.5 1.8 8e-12 44.6 1.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ly49 PF08391.5 KFX88527.1 - 0.084 13.0 1.5 0.17 12.0 1.0 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DivIC PF04977.10 KFX88527.1 - 0.18 11.3 1.0 0.54 9.7 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator APG6 PF04111.7 KFX88527.1 - 0.25 10.3 5.5 0.38 9.7 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 KFX88527.1 - 0.68 9.0 6.8 0.33 10.0 3.1 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 KFX88527.1 - 3 7.4 4.8 5.5 6.5 3.3 1.4 1 0 0 1 1 1 0 IncA protein DUF4239 PF14023.1 KFX88527.1 - 3.1 7.1 4.6 3.7 6.8 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) RNA_pol_Rbc25 PF08292.7 KFX88529.1 - 7.3e-28 97.2 0.0 1.1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KFX88529.1 - 1.9e-15 56.7 0.0 3.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Trypan_PARP PF05887.6 KFX88539.1 - 5.9e-06 26.1 0.3 7.6e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Ferric_reduct PF01794.14 KFX88540.1 - 1.6e-11 44.3 4.7 1.6e-11 44.3 3.3 2.9 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFX88540.1 - 3.7e-10 39.6 0.0 1e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX88540.1 - 1.7e-05 24.7 0.0 7e-05 22.7 0.0 2.0 3 0 0 3 3 3 1 Ferric reductase NAD binding domain SPT6_acidic PF14632.1 KFX88541.1 - 0.28 11.3 4.3 0.54 10.4 3.0 1.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 Ank_2 PF12796.2 KFX88543.1 - 8.5e-109 356.1 19.0 1e-22 80.2 0.1 4.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX88543.1 - 8.9e-64 208.2 15.7 2.8e-09 36.3 0.1 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 KFX88543.1 - 1.2e-49 161.3 8.0 6.4e-06 25.9 0.1 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KFX88543.1 - 2.3e-46 155.3 7.4 1.1e-09 38.5 0.0 7.1 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX88543.1 - 1.4e-38 129.9 15.2 4.4e-07 29.9 0.4 8.7 1 1 8 9 9 9 9 Ankyrin repeats (many copies) RVP PF00077.15 KFX88543.1 - 0.0027 17.6 1.4 46 4.0 0.0 5.0 4 1 1 5 5 5 0 Retroviral aspartyl protease DUF1843 PF08898.5 KFX88543.1 - 0.0062 16.5 0.1 11 6.0 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) DUF3447 PF11929.3 KFX88543.1 - 0.018 14.7 0.0 3.5 7.5 0.0 3.3 3 1 1 4 4 3 0 Domain of unknown function (DUF3447) DUF1691 PF07950.6 KFX88544.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) DUF3767 PF12597.3 KFX88544.1 - 0.17 11.5 2.6 0.25 11.0 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3767) HTH_38 PF13936.1 KFX88546.1 - 0.00038 19.9 1.2 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain CENP-B_N PF04218.8 KFX88546.1 - 0.0032 16.8 2.5 0.0056 16.0 0.6 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain Dsl1_N PF11988.3 KFX88546.1 - 0.028 13.3 0.0 0.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal APH PF01636.18 KFX88546.1 - 0.039 13.6 0.4 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family HTH_24 PF13412.1 KFX88546.1 - 0.055 12.8 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cro PF09048.5 KFX88546.1 - 0.063 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Cro Alpha_GJ PF03229.8 KFX88551.1 - 3 8.2 14.6 0.43 10.9 6.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J Ferritin_2 PF13668.1 KFX88552.1 - 4.7e-20 71.9 0.3 6.6e-20 71.4 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Transketolase_N PF00456.16 KFX88552.1 - 0.036 12.8 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF99 PF01949.11 KFX88553.1 - 0.047 12.7 0.1 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 VirK PF06903.7 KFX88553.1 - 0.06 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 VirK protein FliS PF02561.9 KFX88553.1 - 0.075 12.8 0.3 0.094 12.5 0.2 1.2 1 0 0 1 1 1 0 Flagellar protein FliS SE PF08491.5 KFX88554.1 - 0.0031 16.3 0.0 0.004 16.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DUF445 PF04286.7 KFX88555.1 - 0.016 14.7 0.3 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) 4HB_MCP_1 PF12729.2 KFX88555.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DDE_3 PF13358.1 KFX88556.1 - 3e-17 62.7 0.1 5.1e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KFX88556.1 - 3.8e-07 30.0 1.4 9.2e-07 28.8 0.0 2.4 2 1 1 3 3 3 1 Transposase Sigma70_r4_2 PF08281.7 KFX88556.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.5 KFX88556.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_40 PF14493.1 KFX88556.1 - 0.0035 17.5 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 KFX88556.1 - 0.0066 16.5 0.2 0.013 15.6 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KFX88556.1 - 0.011 15.3 0.3 0.069 12.8 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain UPF0122 PF04297.9 KFX88556.1 - 0.014 15.4 0.1 0.035 14.1 0.0 1.7 2 0 0 2 2 1 0 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.11 KFX88556.1 - 0.037 13.3 0.0 0.12 11.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 TetR_N PF00440.18 KFX88556.1 - 0.039 13.6 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_24 PF13412.1 KFX88556.1 - 0.039 13.3 0.0 0.33 10.3 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF496 PF04363.7 KFX88556.1 - 0.07 12.9 0.1 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF496) HTH_10 PF04967.7 KFX88556.1 - 0.08 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain HTH_7 PF02796.10 KFX88556.1 - 0.082 12.7 0.2 0.59 10.0 0.1 2.5 2 1 1 3 3 3 0 Helix-turn-helix domain of resolvase Zn_Tnp_IS1595 PF12760.2 KFX88556.1 - 0.65 9.8 5.3 0.46 10.3 0.3 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Fungal_trans PF04082.13 KFX88568.1 - 1.6e-18 66.5 0.8 2.5e-18 65.8 0.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88568.1 - 1.6e-07 31.0 13.9 2.8e-07 30.3 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KFX88570.1 - 3.8e-38 130.6 0.0 5.2e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX88570.1 - 0.013 14.5 0.0 0.052 12.5 0.0 2.0 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFX88570.1 - 0.023 14.4 0.1 0.18 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFX88570.1 - 0.035 13.8 0.2 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KFX88570.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_2 PF07724.9 KFX88570.1 - 0.061 13.2 0.2 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KFX88570.1 - 0.07 12.2 0.2 0.16 11.1 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KFX88570.1 - 0.087 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Profilin PF00235.14 KFX88571.1 - 7e-40 135.9 0.8 7.8e-40 135.7 0.6 1.0 1 0 0 1 1 1 1 Profilin Pterin_4a PF01329.14 KFX88572.1 - 1.1e-15 57.1 0.1 1.2e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Mito_carr PF00153.22 KFX88575.1 - 4.4e-60 199.4 2.0 3.7e-24 84.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein ER-remodelling PF14755.1 KFX88581.1 - 1.2 9.2 8.3 1.8 8.6 5.8 1.4 1 1 0 1 1 1 0 Intracellular membrane remodeller Pyr_redox_2 PF07992.9 KFX88585.1 - 3.8e-31 108.5 0.0 5.9e-31 107.9 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX88585.1 - 4e-09 36.7 0.0 6.5e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX88585.1 - 2.5e-06 27.6 0.0 0.045 13.8 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Dmrt1 PF12374.3 KFX88585.1 - 6.2 7.2 12.1 41 4.6 0.4 3.6 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 NAPRTase PF04095.11 KFX88586.1 - 4.7e-48 163.6 0.0 9.8e-47 159.2 0.0 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family MFS_1 PF07690.11 KFX88587.1 - 9e-20 70.6 78.6 1.4e-14 53.5 28.7 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 KFX88588.1 - 3.4e-26 92.5 10.4 5.8e-16 58.8 0.7 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 bZIP_1 PF00170.16 KFX88589.1 - 2.8e-06 27.2 8.3 5.8e-06 26.1 5.8 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX88589.1 - 0.013 15.3 7.0 0.021 14.6 4.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.12 KFX88589.1 - 1.5 9.1 8.2 0.11 12.8 2.5 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF605 PF04652.11 KFX88589.1 - 2.5 7.4 12.4 3 7.1 8.6 1.1 1 0 0 1 1 1 0 Vta1 like GAS2 PF02187.12 KFX88593.1 - 0.0001 21.9 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Glyco_hydro_61 PF03443.9 KFX88595.1 - 4.7e-66 222.7 0.1 7.3e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KFX88595.1 - 1.1e-11 44.1 10.2 3.3e-11 42.6 7.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Amino_oxidase PF01593.19 KFX88596.1 - 2.1e-35 122.6 0.0 1.8e-34 119.6 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFX88596.1 - 1.8e-11 43.8 0.0 5.9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX88596.1 - 2.4e-05 24.5 0.1 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX88596.1 - 0.0002 19.9 0.1 0.00034 19.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFX88596.1 - 0.0012 17.9 0.3 0.0019 17.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX88596.1 - 0.0078 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFX88596.1 - 0.009 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KFX88596.1 - 0.013 15.9 0.1 0.032 14.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX88596.1 - 0.032 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KFX88596.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_C PF05199.8 KFX88597.1 - 3.3e-31 108.5 0.0 6e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KFX88597.1 - 1.4e-30 106.5 0.0 3.7e-25 88.6 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KFX88597.1 - 0.00037 20.4 2.0 0.0015 18.5 1.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX88597.1 - 0.00088 18.2 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX88597.1 - 0.0076 15.1 0.8 0.19 10.5 0.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX88597.1 - 0.016 15.1 0.1 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX88597.1 - 0.034 13.0 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 KFX88597.1 - 0.037 13.4 0.5 0.067 12.6 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KFX88597.1 - 0.041 13.9 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX88597.1 - 0.072 11.5 0.3 0.1 11.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFX88597.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX88597.1 - 0.17 11.6 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus dCMP_cyt_deam_1 PF00383.17 KFX88603.1 - 1.7e-14 53.2 0.1 2.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KFX88603.1 - 0.0004 20.0 0.0 0.00058 19.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 KFX88603.1 - 0.026 14.2 0.1 0.046 13.4 0.0 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Mit_ribos_Mrp51 PF11709.3 KFX88604.1 - 3.9e-82 275.9 0.1 4.6e-82 275.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF3145 PF11343.3 KFX88604.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Takusan PF04822.8 KFX88604.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Takusan Ribosomal_S17e PF00833.13 KFX88605.1 - 4.1e-59 197.6 0.5 5e-59 197.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KFX88605.1 - 0.074 13.7 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 KFX88606.1 - 7.1e-16 58.0 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_9 PF14604.1 KFX88607.1 - 7.9e-11 41.3 0.3 2.6e-10 39.7 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFX88607.1 - 8e-10 37.9 0.2 2e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFX88607.1 - 2.2e-09 36.6 0.1 5.5e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Pectate_lyase_3 PF12708.2 KFX88609.1 - 1e-87 293.9 28.0 9.8e-71 238.4 4.3 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein WSC PF01822.14 KFX88609.1 - 1.4e-18 66.5 6.6 3.6e-18 65.2 4.6 1.8 1 0 0 1 1 1 1 WSC domain End_N_terminal PF12218.3 KFX88609.1 - 4e-07 29.3 3.4 0.0093 15.4 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_cc PF11790.3 KFX88610.1 - 1.9e-57 194.4 5.8 2.4e-57 194.1 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WSC PF01822.14 KFX88610.1 - 2.9e-19 68.7 17.3 6e-19 67.7 7.1 2.6 2 0 0 2 2 2 2 WSC domain GSu_C4xC__C2xCH PF09698.5 KFX88610.1 - 0.0016 18.6 1.3 0.012 15.7 0.9 2.7 1 0 0 1 1 1 1 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DUF1996 PF09362.5 KFX88611.1 - 3.2e-09 36.8 0.4 3.8e-09 36.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glycoprotein_B PF00606.13 KFX88612.1 - 0.049 11.6 3.2 0.056 11.4 2.2 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF4233 PF14017.1 KFX88612.1 - 0.14 12.0 11.0 0.079 12.8 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Herpes_LAMP2 PF06126.6 KFX88612.1 - 0.23 9.8 4.2 0.27 9.5 2.9 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Tic20 PF09685.5 KFX88612.1 - 1.8 8.5 7.6 9.1 6.3 0.0 2.1 1 1 1 2 2 2 0 Tic20-like protein MFS_1 PF07690.11 KFX88613.1 - 2.6e-25 88.9 45.6 1.6e-19 69.8 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX88613.1 - 3.1e-10 39.2 7.0 3.1e-10 39.2 4.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX88613.1 - 0.0002 19.8 20.2 0.0058 15.0 3.7 4.3 2 2 2 4 4 4 3 MFS/sugar transport protein Img2 PF05046.9 KFX88615.1 - 3.1e-21 75.4 0.2 5.5e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 KFX88616.1 - 5.2e-49 165.8 3.5 1.2e-48 164.6 2.4 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KFX88616.1 - 1.4e-13 51.0 0.2 3.6e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 PCI domain DUF718 PF05336.8 KFX88616.1 - 0.0021 17.8 0.1 0.005 16.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF718) VPR PF00522.13 KFX88616.1 - 0.063 13.0 0.2 0.61 9.9 0.0 2.7 3 0 0 3 3 3 0 VPR/VPX protein DUF4267 PF14087.1 KFX88617.1 - 2.1e-17 62.7 1.4 2.5e-17 62.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.1 KFX88617.1 - 0.029 13.8 2.5 0.044 13.2 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) PGAP1 PF07819.8 KFX88622.1 - 0.00018 21.2 0.0 0.00058 19.5 0.0 1.9 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFX88622.1 - 0.0087 15.9 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX88622.1 - 0.06 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Atrophin-1 PF03154.10 KFX88622.1 - 0.3 9.2 1.0 0.52 8.3 0.7 1.3 1 0 0 1 1 1 0 Atrophin-1 family AAA PF00004.24 KFX88623.1 - 1.5e-16 60.7 0.0 6.3e-16 58.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX88623.1 - 9.6e-05 22.5 0.4 0.0061 16.6 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX88623.1 - 0.0046 16.9 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KFX88623.1 - 0.0056 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CPT PF07931.7 KFX88623.1 - 0.011 15.3 0.0 0.12 11.9 0.0 2.4 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.12 KFX88623.1 - 0.029 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KFX88623.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 KFX88623.1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RuvB_N PF05496.7 KFX88623.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFX88623.1 - 0.14 13.0 3.6 0.24 12.2 0.0 3.0 2 1 1 3 3 3 0 AAA domain Mid2 PF04478.7 KFX88629.1 - 0.0029 17.0 0.0 0.0081 15.5 0.0 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_6 PF13964.1 KFX88629.1 - 0.0042 17.2 3.3 0.37 11.0 0.0 4.0 4 0 0 4 4 4 1 Kelch motif Herpes_gE PF02480.11 KFX88629.1 - 0.029 12.6 0.0 0.049 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_UL45 PF05473.7 KFX88629.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UL45 protein Adeno_E3_CR2 PF02439.10 KFX88629.1 - 0.3 10.6 1.1 0.62 9.6 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cellulase PF00150.13 KFX88630.1 - 1.9e-31 109.3 0.0 2.3e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) KRBA1 PF15287.1 KFX88632.1 - 0.04 13.2 0.4 0.081 12.2 0.3 1.5 1 0 0 1 1 1 0 KRBA1 family repeat p450 PF00067.17 KFX88634.1 - 1.1e-50 172.5 0.0 1.5e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.8 KFX88635.1 - 1.2e-11 44.6 0.7 2.6e-11 43.5 0.5 1.6 1 1 0 1 1 1 1 Putative cyclase HD PF01966.17 KFX88636.1 - 3.4e-07 30.3 0.9 9.7e-07 28.8 0.2 1.9 2 0 0 2 2 2 1 HD domain Carboxyl_trans PF01039.17 KFX88637.1 - 1.3e-77 261.2 0.0 1.7e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KFX88638.1 - 1.8e-55 187.4 0.0 2.5e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFX88638.1 - 3.1e-30 104.3 0.0 5.3e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFX88638.1 - 1.1e-25 89.8 0.0 2.1e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX88638.1 - 1.8e-15 57.1 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX88638.1 - 1.2e-13 50.5 0.0 1.5e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KFX88638.1 - 5.7e-11 41.8 0.7 3.9e-10 39.2 1.0 2.1 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KFX88638.1 - 2.5e-05 23.7 0.0 4.4e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFX88638.1 - 0.00011 21.6 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFX88638.1 - 0.00095 19.0 0.0 0.0029 17.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFX88638.1 - 0.0028 17.1 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF2118 PF09891.4 KFX88638.1 - 0.0035 17.0 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 KFX88638.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KFX88638.1 - 0.032 13.8 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like RnfC_N PF13375.1 KFX88638.1 - 0.037 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.1 KFX88638.1 - 0.28 10.2 0.0 0.48 9.4 0.0 1.4 1 1 0 1 1 1 0 Sugar-transfer associated ATP-grasp SNF2_N PF00176.18 KFX88640.1 - 7.7e-52 175.9 0.0 1.3e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 KFX88640.1 - 6.4e-24 83.6 0.3 1.9e-23 82.1 0.2 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 KFX88640.1 - 6.4e-15 54.7 0.0 3.1e-14 52.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX88640.1 - 3.3e-06 27.0 0.0 4.7e-05 23.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX88640.1 - 4.2e-05 23.1 0.0 0.00013 21.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase But2 PF09792.4 KFX88641.1 - 3.1e-19 69.1 0.5 7.1e-19 67.9 0.1 1.8 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.11 KFX88642.1 - 1.3e-36 126.0 53.8 2.2e-36 125.3 37.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NmrA PF05368.8 KFX88642.1 - 3.7e-31 108.1 0.0 1.3e-30 106.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX88642.1 - 3.7e-09 36.8 0.0 7.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX88642.1 - 0.0045 15.7 0.0 0.0066 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Dpy19 PF10034.4 KFX88642.1 - 0.29 9.2 0.1 0.45 8.6 0.0 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation OATP PF03137.15 KFX88642.1 - 5.5 4.9 8.4 2 6.3 2.7 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydr_30_2 PF14587.1 KFX88643.1 - 4.8e-17 61.9 6.5 8.4e-17 61.1 4.5 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 KFX88643.1 - 0.00083 19.1 0.1 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Alpha-L-AF_C PF06964.7 KFX88644.1 - 2.3e-33 115.4 0.1 3.3e-33 114.9 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Oxidored_molyb PF00174.14 KFX88645.1 - 1.3e-46 158.0 0.0 2.2e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KFX88645.1 - 2e-36 124.5 0.2 3.8e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KFX88645.1 - 2.2e-24 86.0 0.0 8.8e-24 84.1 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFX88645.1 - 2.4e-21 75.6 0.0 1.5e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KFX88645.1 - 1.6e-14 53.4 0.1 3.6e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFX88645.1 - 0.022 14.6 0.0 1.5 8.7 0.0 2.8 1 1 0 2 2 2 0 Ferric reductase NAD binding domain p450 PF00067.17 KFX88646.1 - 9.8e-57 192.4 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1705 PF08019.7 KFX88647.1 - 0.98 8.9 13.2 0.11 12.0 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) Methyltransf_2 PF00891.13 KFX88648.1 - 2.8e-26 92.2 0.0 5.5e-26 91.2 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Acyl-CoA_dh_1 PF00441.19 KFX88648.1 - 1.2e-22 80.6 0.5 2.4e-22 79.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX88648.1 - 2.1e-11 44.3 0.1 1.1e-10 42.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFX88648.1 - 1.6e-08 33.9 0.1 3.7e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX88648.1 - 4.5e-06 26.9 0.8 1e-05 25.7 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HTH_24 PF13412.1 KFX88648.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sugar_tr PF00083.19 KFX88649.1 - 6.3e-106 354.6 26.4 7.3e-106 354.4 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88649.1 - 1.3e-19 70.1 41.7 5e-13 48.4 7.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily CDC45 PF02724.9 KFX88650.1 - 1.5 6.7 5.4 1.6 6.6 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein CFEM PF05730.6 KFX88651.1 - 3.5e-73 241.3 108.4 2.5e-11 43.2 5.9 7.6 7 0 0 7 7 7 7 CFEM domain Esterase_phd PF10503.4 KFX88652.1 - 1e-25 90.2 0.2 1.4e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX88652.1 - 4.6e-08 32.5 0.9 9.1e-08 31.5 0.6 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX88652.1 - 1.2e-05 25.0 0.1 2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX88652.1 - 0.012 14.3 0.3 0.02 13.6 0.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.11 KFX88654.1 - 6.7e-35 120.4 25.9 9.9e-35 119.8 18.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCHC PF00098.18 KFX88656.1 - 2.3e-53 175.7 60.7 1.9e-09 36.9 1.2 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KFX88656.1 - 6.2e-11 41.7 39.8 0.19 11.3 0.1 7.4 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KFX88656.1 - 8.3e-07 28.6 49.8 0.027 14.2 0.3 7.0 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 KFX88656.1 - 0.022 14.2 0.4 0.022 14.2 0.3 7.4 3 2 4 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 KFX88656.1 - 0.035 13.7 48.0 0.06 13.0 1.3 7.1 5 2 2 7 7 7 0 Zinc knuckle RMF PF04957.7 KFX88656.1 - 9.8 5.9 15.7 1.8 8.2 0.9 3.7 3 1 1 4 4 4 0 Ribosome modulation factor CFEM PF05730.6 KFX88659.1 - 1.4e-10 40.8 13.8 2.4e-10 40.0 9.6 1.4 1 0 0 1 1 1 1 CFEM domain DUF566 PF04484.7 KFX88659.1 - 0.36 10.3 3.3 0.5 9.8 2.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2404 PF10296.4 KFX88661.1 - 0.0037 17.3 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) HpaP PF09483.5 KFX88663.1 - 0.63 9.9 9.0 0.93 9.4 6.3 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) adh_short PF00106.20 KFX88665.1 - 3.9e-14 52.9 0.4 5.9e-14 52.3 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX88665.1 - 4.6e-09 36.1 0.4 7.8e-09 35.4 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX88665.1 - 2.8e-05 24.0 0.0 0.0066 16.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase PAD PF03068.10 KFX88665.1 - 0.035 12.5 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) RabGAP-TBC PF00566.13 KFX88668.1 - 5.8e-47 159.9 0.0 1e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IncA PF04156.9 KFX88668.1 - 0.088 12.3 5.1 3.5 7.1 0.1 3.0 2 0 0 2 2 2 0 IncA protein Glyco_hydro_61 PF03443.9 KFX88680.1 - 4.8e-42 144.2 0.0 5.9e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.23 KFX88683.1 - 2.1e-78 264.3 0.2 5.1e-78 263.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX88683.1 - 3.8e-12 46.2 0.0 7.7e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX88683.1 - 0.073 12.8 1.3 0.11 12.2 0.4 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family TauD PF02668.11 KFX88685.1 - 1.2e-15 57.9 1.2 7.9e-15 55.2 0.8 2.0 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFX88685.1 - 0.0063 15.4 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 CsiD CP_ATPgrasp_2 PF14403.1 KFX88685.1 - 0.011 14.3 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Fungal_trans PF04082.13 KFX88686.1 - 5.2e-06 25.5 0.2 0.001 17.9 0.1 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88686.1 - 2.2e-05 24.2 10.3 4.8e-05 23.1 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 KFX88687.1 - 3.6e-129 431.4 2.6 4.8e-129 431.0 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX88687.1 - 0.0005 19.8 2.7 0.0012 18.6 0.1 2.8 3 1 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.19 KFX88688.1 - 5.6e-85 285.5 24.2 6.7e-85 285.3 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88688.1 - 5.6e-20 71.3 26.4 5.6e-20 71.3 18.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_39 PF01229.12 KFX88689.1 - 0.004 15.6 0.2 0.0055 15.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_43 PF04616.9 KFX88690.1 - 2e-45 155.0 3.4 2.8e-45 154.6 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_3 PF01494.14 KFX88691.1 - 3.4e-15 55.9 0.0 4.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain APG6 PF04111.7 KFX88692.1 - 0.053 12.5 2.6 0.089 11.8 1.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KFX88692.1 - 0.099 11.8 1.1 0.15 11.1 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4106 PF13388.1 KFX88696.1 - 1.7 7.5 6.6 2.4 7.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Peptidase_C48 PF02902.14 KFX88697.1 - 0.00033 20.3 0.1 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.24 KFX88697.1 - 0.0099 15.5 10.4 0.021 14.4 7.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KFX88697.1 - 6 6.6 9.5 3.3 7.5 4.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF3295 PF11702.3 KFX88699.1 - 1e-103 348.0 30.0 7.2e-92 308.9 14.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) zf-U1 PF06220.7 KFX88699.1 - 0.098 12.2 0.2 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 U1 zinc finger Methyltransf_23 PF13489.1 KFX88700.1 - 2.5e-16 59.8 0.0 4.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX88700.1 - 2.9e-06 27.6 0.0 8e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX88700.1 - 5.4e-06 26.8 0.0 0.0002 21.7 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX88700.1 - 7.7e-06 25.5 0.0 0.0001 21.9 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX88700.1 - 1.7e-05 25.3 0.1 0.00018 22.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX88700.1 - 0.0033 17.7 0.0 0.038 14.3 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFX88700.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 KFX88700.1 - 0.018 14.1 0.0 0.082 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 KFX88700.1 - 0.039 13.9 0.0 0.088 12.7 0.0 1.6 1 1 1 2 2 2 0 FtsJ-like methyltransferase RRM_1 PF00076.17 KFX88701.1 - 5.5e-21 73.9 0.0 2.7e-09 36.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HD_3 PF13023.1 KFX88701.1 - 6.8e-19 68.1 0.1 1.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 HD domain Abhydrolase_3 PF07859.8 KFX88701.1 - 8.3e-19 67.9 0.0 5.3e-17 62.1 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold RRM_6 PF14259.1 KFX88701.1 - 1.2e-10 41.2 0.0 0.00022 21.1 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_5 PF12695.2 KFX88701.1 - 6.8e-09 35.6 0.0 2e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADK PF00406.17 KFX88701.1 - 2.2e-08 34.1 0.0 4.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase Peptidase_S9 PF00326.16 KFX88701.1 - 6.8e-08 31.9 0.0 1.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFX88701.1 - 9.1e-07 28.9 0.0 9.4e-06 25.6 0.0 2.7 2 1 0 2 2 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX88701.1 - 6.8e-05 21.7 0.0 0.00017 20.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 KFX88701.1 - 0.00072 18.9 0.0 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 KFX88701.1 - 0.0044 15.9 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AAA_17 PF13207.1 KFX88701.1 - 0.01 16.6 0.0 0.26 12.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Chlorophyllase PF07224.6 KFX88701.1 - 0.055 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase SLT_2 PF13406.1 KFX88701.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain HD PF01966.17 KFX88701.1 - 0.17 11.9 0.0 0.53 10.3 0.0 1.8 1 0 0 1 1 1 0 HD domain AXE1 PF05448.7 KFX88701.1 - 0.29 9.6 0.0 0.75 8.2 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zn_clus PF00172.13 KFX88701.1 - 0.73 9.7 9.0 1.8 8.5 6.2 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DENN PF02141.16 KFX88704.1 - 6.3e-40 136.8 0.0 1.1e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFX88704.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 KFX88704.1 - 0.0059 16.9 4.3 0.0059 16.9 3.0 2.4 2 1 1 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Melibiase PF02065.13 KFX88709.1 - 8.9e-25 87.1 0.5 5.9e-18 64.7 0.0 3.6 1 1 1 2 2 2 2 Melibiase Alpha-amylase PF00128.19 KFX88710.1 - 5.5e-30 104.8 0.9 1.2e-29 103.7 0.6 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KFX88710.1 - 0.00071 17.4 0.2 1.9 6.1 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 KFX88710.1 - 0.0027 17.5 0.2 0.0078 16.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) Fungal_trans PF04082.13 KFX88713.1 - 2.3e-16 59.4 3.2 3.9e-16 58.7 2.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 KFX88715.1 - 4.4e-35 120.8 0.0 5.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Bestrophin PF01062.16 KFX88717.1 - 2.6e-51 174.3 0.2 3e-49 167.5 0.1 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ank_2 PF12796.2 KFX88718.1 - 1e-123 403.9 17.8 4.3e-21 75.0 0.1 10.3 3 3 4 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFX88718.1 - 2.3e-101 326.9 50.8 1.4e-06 27.7 0.1 22.4 23 0 0 23 23 23 19 Ankyrin repeat Ank_3 PF13606.1 KFX88718.1 - 5.9e-87 276.8 25.3 1.6e-05 24.6 0.0 22.6 23 0 0 23 23 23 18 Ankyrin repeat Ank_4 PF13637.1 KFX88718.1 - 2.8e-73 241.0 20.6 3e-08 33.9 0.1 17.2 8 4 11 19 19 19 17 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX88718.1 - 5.5e-58 191.6 33.6 5.5e-07 29.6 0.2 18.3 9 4 9 19 19 19 14 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFX88718.1 - 5.7e-06 26.0 0.3 1.3 8.4 0.0 6.2 5 2 3 8 8 8 1 Shigella flexneri OspC protein AA_kinase PF00696.23 KFX88718.1 - 0.082 12.4 2.0 4.2 6.8 0.0 3.7 3 1 0 4 4 4 0 Amino acid kinase family Phage_T7_Capsid PF05396.6 KFX88718.1 - 8.2 6.5 6.3 19 5.4 0.0 4.2 5 1 1 6 6 6 0 Phage T7 capsid assembly protein UPAR_LY6 PF00021.16 KFX88719.1 - 0.29 11.5 1.1 0.94 9.9 0.1 2.1 2 0 0 2 2 2 0 u-PAR/Ly-6 domain COesterase PF00135.23 KFX88720.1 - 3e-75 253.9 0.2 4.5e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX88720.1 - 0.00065 19.3 0.8 0.0037 16.8 0.1 2.5 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX88720.1 - 0.0074 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3290 PF11694.3 KFX88723.1 - 0.054 13.2 0.5 0.094 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF4293 PF14126.1 KFX88723.1 - 0.15 11.9 5.3 0.03 14.2 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) MARVEL PF01284.18 KFX88723.1 - 0.37 10.6 17.1 0.52 10.1 11.8 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2085 PF09858.4 KFX88723.1 - 4.2 7.5 6.4 0.88 9.6 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Oxidored_q1_N PF00662.15 KFX88723.1 - 4.2 7.0 9.3 11 5.7 0.6 2.7 1 1 1 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus APH PF01636.18 KFX88725.1 - 3.7e-20 72.6 0.0 7.4e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_25 PF01183.15 KFX88726.1 - 4.8e-40 137.3 0.5 5.5e-40 137.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 NAD_binding_10 PF13460.1 KFX88727.1 - 5.5e-09 36.2 0.0 6.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX88727.1 - 0.0024 16.8 0.0 0.012 14.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 KFX88727.1 - 0.0049 16.3 0.1 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX88727.1 - 0.042 14.1 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KFX88727.1 - 0.063 13.1 0.1 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase p450 PF00067.17 KFX88728.1 - 1.2e-45 155.9 0.0 1e-42 146.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 Amidohydro_4 PF13147.1 KFX88732.1 - 1.7e-07 31.5 0.4 2.8e-07 30.8 0.3 1.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KFX88732.1 - 2.3e-06 27.4 0.1 4e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX88732.1 - 0.0045 16.6 0.5 0.045 13.4 0.4 2.1 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 KFX88732.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_18 PF00704.23 KFX88733.1 - 9.4e-44 150.2 4.3 1.8e-43 149.3 3.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFX88733.1 - 5.6e-07 29.3 0.9 0.025 14.4 0.0 3.4 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 KFX88733.1 - 0.003 17.4 3.1 0.003 17.4 2.1 3.3 2 0 0 2 2 2 1 Chitin recognition protein RTA1 PF04479.8 KFX88734.1 - 2.6e-27 95.7 3.4 3.6e-27 95.3 2.3 1.1 1 0 0 1 1 1 1 RTA1 like protein COX15-CtaA PF02628.10 KFX88735.1 - 5.7e-50 169.8 0.8 6.7e-50 169.6 0.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein TPT PF03151.11 KFX88736.1 - 1.9e-06 27.5 4.0 5.5e-06 26.0 2.8 1.7 1 0 0 1 1 1 1 Triose-phosphate Transporter family PAN_1 PF00024.21 KFX88744.1 - 0.00013 21.6 13.2 0.012 15.3 0.7 3.1 3 1 0 3 3 3 2 PAN domain PA14_2 PF10528.4 KFX88746.1 - 1.1e-23 83.3 0.1 2.4e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 GLEYA domain Pyr_redox_3 PF13738.1 KFX88746.1 - 3.2e-22 79.5 0.0 5.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PA14 PF07691.7 KFX88746.1 - 2.6e-05 23.9 0.2 5.2e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 PA14 domain K_oxygenase PF13434.1 KFX88746.1 - 0.00047 19.1 0.0 0.0011 17.9 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX88746.1 - 0.0018 18.1 0.0 0.0077 16.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PAN_4 PF14295.1 KFX88746.1 - 0.0051 16.4 1.2 0.0051 16.4 0.8 3.1 3 0 0 3 3 3 2 PAN domain PHO4 PF01384.15 KFX88747.1 - 4.7e-101 337.6 12.2 5.6e-101 337.4 8.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Zn_clus PF00172.13 KFX88749.1 - 1.2e-08 34.7 11.6 1.8e-08 34.1 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX88749.1 - 0.00021 19.9 0.8 0.00035 19.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain AA_permease_2 PF13520.1 KFX88750.1 - 5.3e-54 183.3 43.9 1.6e-44 152.1 21.5 3.7 2 2 1 3 3 3 2 Amino acid permease RTA1 PF04479.8 KFX88750.1 - 5.6e-31 107.7 1.9 5.6e-31 107.7 1.3 2.4 2 1 0 2 2 2 1 RTA1 like protein AA_permease PF00324.16 KFX88750.1 - 7.8e-12 44.2 37.4 7.8e-12 44.2 26.0 3.1 2 1 0 2 2 2 1 Amino acid permease DUF3092 PF11289.3 KFX88750.1 - 0.01 15.0 1.7 0.022 14.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Amidohydro_2 PF04909.9 KFX88753.1 - 3.1e-15 56.4 0.0 3.8e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase APH PF01636.18 KFX88754.1 - 1.3e-09 38.1 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX88754.1 - 3.8e-06 26.6 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase adh_short_C2 PF13561.1 KFX88755.1 - 5.3e-25 88.5 0.1 7.7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX88755.1 - 5.2e-17 62.2 5.7 7.4e-17 61.7 4.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Hydrolase_3 PF08282.7 KFX88756.1 - 9.8e-13 48.2 0.0 5.4e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.8 KFX88756.1 - 3.2e-10 39.9 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 KFX88756.1 - 0.015 14.5 0.0 0.085 12.1 0.0 2.0 2 1 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.11 KFX88756.1 - 0.025 13.4 0.0 0.037 12.9 0.0 1.4 1 1 0 1 1 1 0 Trehalose-phosphatase Alpha-amylase PF00128.19 KFX88757.1 - 1.1e-64 218.8 0.0 1.5e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KFX88757.1 - 1.4e-22 79.5 0.0 3.2e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) IlvC PF01450.14 KFX88757.1 - 0.0094 15.8 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Aft1_HRR PF11787.3 KFX88757.1 - 0.061 14.3 1.3 0.19 12.8 0.9 1.8 1 0 0 1 1 1 0 Aft1 HRR domain Aminotran_5 PF00266.14 KFX88757.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V BTB PF00651.26 KFX88758.1 - 1.9e-07 31.0 1.1 3.4e-05 23.8 0.2 3.0 2 1 0 2 2 2 1 BTB/POZ domain Peptidase_C97 PF05903.9 KFX88768.1 - 5.3e-32 110.6 0.0 8.4e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KFX88768.1 - 0.00025 21.0 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 KFX88768.1 - 0.099 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.14 KFX88769.1 - 9.2e-12 45.1 0.1 1.6e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 KFX88770.1 - 1.5e-32 112.6 0.0 3.7e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF1510 PF07423.6 KFX88770.1 - 0.017 14.5 14.1 0.041 13.2 9.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HPIP PF15226.1 KFX88770.1 - 0.054 13.5 0.1 2 8.4 0.0 2.4 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family Dus PF01207.12 KFX88771.1 - 2.7e-54 184.1 0.0 1.1e-53 182.1 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KFX88771.1 - 0.00019 20.5 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.12 KFX88771.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Na_Ca_ex PF01699.19 KFX88772.1 - 5e-40 136.3 31.0 4.2e-22 78.2 9.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GAGA_bind PF06217.7 KFX88772.1 - 0.27 11.1 6.9 0.48 10.3 4.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDRGK PF09756.4 KFX88772.1 - 0.85 9.0 13.3 1.4 8.2 9.2 1.2 1 0 0 1 1 1 0 DDRGK domain Peptidase_S49_N PF08496.5 KFX88772.1 - 4.2 7.1 7.8 10 5.9 5.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.20 KFX88773.1 - 2.5e-63 213.6 0.0 4.9e-63 212.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88773.1 - 2.2e-35 121.9 0.0 2.6e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX88773.1 - 2.1e-05 23.6 0.0 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFX88773.1 - 0.0045 16.7 0.0 0.0045 16.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX88773.1 - 0.0055 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFX88773.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GWT1 PF06423.7 KFX88774.1 - 9.8e-41 139.0 2.1 2.3e-40 137.8 1.4 1.7 1 0 0 1 1 1 1 GWT1 DUF1129 PF06570.6 KFX88774.1 - 0.12 11.6 1.3 0.74 9.0 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3972 PF13118.1 KFX88780.1 - 0.0087 16.1 0.1 0.033 14.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3972) Ycf1 PF05758.7 KFX88781.1 - 0.89 7.1 2.4 0.95 7.0 1.7 1.0 1 0 0 1 1 1 0 Ycf1 Ank_2 PF12796.2 KFX88784.1 - 5.3e-62 206.1 0.5 8.9e-22 77.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX88784.1 - 2.8e-58 190.9 0.0 9.7e-09 34.6 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFX88784.1 - 1.5e-47 159.1 4.3 1.4e-09 38.2 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX88784.1 - 4.6e-42 137.8 0.0 1.6e-05 24.6 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KFX88784.1 - 9.2e-33 111.5 0.1 8.8e-08 32.1 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) FAD_binding_3 PF01494.14 KFX88785.1 - 1.6e-14 53.7 0.0 1.3e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFX88785.1 - 0.0017 18.3 0.0 0.0048 16.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX88785.1 - 0.0034 16.3 0.0 0.53 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFX88785.1 - 0.033 13.2 0.2 0.28 10.2 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF1460 PF07313.7 KFX88785.1 - 0.12 11.4 0.2 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Lycopene_cycl PF05834.7 KFX88785.1 - 0.17 10.8 0.5 2.7 6.7 0.0 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 KFX88785.1 - 0.32 11.4 0.6 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.2 KFX88786.1 - 1.1e-29 103.9 0.0 2.2e-29 102.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX88786.1 - 8.5e-11 41.8 0.3 1.6e-10 40.9 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX88786.1 - 1.4e-07 31.3 0.0 5.9e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX88786.1 - 0.0023 17.3 0.1 1.2 8.4 0.0 2.8 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase MFS_1 PF07690.11 KFX88787.1 - 2.7e-37 128.3 66.6 3.6e-33 114.7 36.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KFX88787.1 - 1.1e-12 47.9 0.0 2.7e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX88787.1 - 7.7e-10 37.9 0.2 1.6e-09 36.9 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX88787.1 - 7.7e-09 35.8 0.4 1.7e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX88787.1 - 0.00066 18.6 1.2 0.001 18.0 0.1 1.9 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 KFX88787.1 - 0.11 11.7 0.4 0.2 10.8 0.3 1.5 1 0 0 1 1 1 0 NmrA-like family Fungal_trans PF04082.13 KFX88788.1 - 6.9e-15 54.6 0.1 1.1e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phospholip_A2_3 PF09056.6 KFX88789.1 - 6.5e-38 129.3 5.5 9.4e-38 128.8 3.8 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Bacteriocin_IIi PF11758.3 KFX88790.1 - 0.091 12.3 1.7 0.21 11.2 1.2 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin CEP19 PF14933.1 KFX88790.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 CEP19-like protein Dynamin_N PF00350.18 KFX88791.1 - 3.5e-08 33.4 1.0 0.0036 17.1 0.2 2.6 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 KFX88791.1 - 2.2e-07 30.8 0.1 5.2e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFX88791.1 - 0.00024 20.3 0.1 0.00037 19.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 KFX88791.1 - 0.00059 19.1 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFX88791.1 - 0.003 18.0 0.1 0.0072 16.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KFX88791.1 - 0.0062 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 KFX88791.1 - 0.0081 15.3 0.6 0.031 13.4 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX88791.1 - 0.026 14.6 0.0 0.089 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KFX88791.1 - 0.035 13.1 0.3 0.19 10.6 0.2 2.1 1 1 0 1 1 1 0 Septin ABC_tran PF00005.22 KFX88791.1 - 0.13 12.5 1.9 0.32 11.2 0.1 2.2 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 KFX88791.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 KFX88791.1 - 0.19 12.5 0.5 0.43 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFX88791.1 - 0.82 8.4 3.6 0.5 9.1 0.3 2.0 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 KFX88791.1 - 1.6 8.2 6.3 0.19 11.2 1.2 1.7 2 0 0 2 2 2 0 AAA domain Abhydrolase_3 PF07859.8 KFX88793.1 - 3.6e-25 88.7 0.0 4.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX88793.1 - 5.9e-08 31.7 0.0 9.1e-08 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFX88793.1 - 0.0025 17.5 0.1 0.0038 16.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX88793.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Sugar_tr PF00083.19 KFX88794.1 - 8.8e-32 110.2 26.3 1.5e-31 109.4 18.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Phosphodiest PF01663.17 KFX88794.1 - 1.6e-27 96.7 0.0 2.7e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 KFX88794.1 - 6.4e-14 51.4 30.5 6.4e-13 48.1 15.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HD PF01966.17 KFX88794.1 - 3.4e-07 30.3 0.1 6.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KFX88794.1 - 0.066 12.4 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 HDOD domain HD_4 PF13328.1 KFX88794.1 - 0.072 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 HD domain PhyH PF05721.8 KFX88795.1 - 5e-29 101.8 0.1 6.5e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KFX88795.1 - 0.00021 21.5 0.1 0.00046 20.4 0.1 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.13 KFX88796.1 - 6.6e-09 35.5 9.7 1.1e-08 34.8 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX88796.1 - 0.047 12.5 0.1 0.15 10.8 0.1 1.8 1 1 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_88 PF07470.8 KFX88797.1 - 3.8e-72 243.1 1.2 4.9e-72 242.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFX88797.1 - 0.0011 17.3 0.0 0.0014 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_2 PF13249.1 KFX88797.1 - 0.031 14.6 0.4 0.14 12.5 0.1 2.2 2 0 0 2 2 2 0 Prenyltransferase-like Glyco_hydro_47 PF01532.15 KFX88797.1 - 0.096 11.3 0.2 3.4 6.2 0.0 2.8 3 1 0 3 3 3 0 Glycosyl hydrolase family 47 Porin_3 PF01459.17 KFX88801.1 - 2.3e-64 217.3 5.8 2.6e-64 217.1 4.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin His_Phos_1 PF00300.17 KFX88802.1 - 4.6e-25 88.5 0.0 5.4e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Utp21 PF04192.7 KFX88807.1 - 1e-74 250.6 0.0 1.5e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KFX88807.1 - 3.4e-24 83.7 14.7 4e-06 26.4 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFX88807.1 - 1.1e-07 30.5 0.0 2.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KFX88807.1 - 0.00012 20.3 0.5 0.084 10.9 0.1 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KFX88807.1 - 0.0042 16.8 0.1 0.092 12.4 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A TPT PF03151.11 KFX88811.1 - 3.1e-17 62.6 11.0 3.1e-17 62.6 7.6 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFX88811.1 - 1.8e-05 24.7 9.8 1.8e-05 24.7 6.8 2.9 2 1 1 3 3 3 1 EamA-like transporter family CRPA PF05745.6 KFX88811.1 - 0.067 12.9 0.2 0.067 12.9 0.2 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tuberculin PF12198.3 KFX88811.1 - 0.093 12.6 0.2 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Theoretical tuberculin protein zf-C2H2_4 PF13894.1 KFX88813.1 - 0.035 14.4 0.3 0.035 14.4 0.2 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX88813.1 - 0.046 14.0 10.2 0.63 10.5 1.0 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 KFX88814.1 - 4.2e-19 68.8 0.0 8e-19 67.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 BAG PF02179.11 KFX88831.1 - 1.9e-19 69.5 0.0 4.1e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KFX88831.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFX88831.1 - 0.0017 18.4 0.1 0.0036 17.4 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2201_N PF13203.1 KFX88831.1 - 0.23 10.6 2.3 0.35 9.9 1.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain BLVR PF06375.6 KFX88831.1 - 0.42 10.4 7.5 0.64 9.8 4.8 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Corona_nucleoca PF00937.13 KFX88834.1 - 0.0031 16.5 18.7 0.043 12.7 7.7 2.2 2 0 0 2 2 2 2 Coronavirus nucleocapsid protein DUF1509 PF07420.6 KFX88834.1 - 0.19 10.9 28.8 0.24 10.6 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) DUF566 PF04484.7 KFX88834.1 - 1.3 8.4 12.4 0.25 10.8 2.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF566) DUF4246 PF14033.1 KFX88835.1 - 1.4e-180 601.2 0.6 1.8e-180 600.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KFX88835.1 - 0.02 15.1 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ABC2_membrane PF01061.19 KFX88836.1 - 4.6e-37 127.2 20.3 9.2e-37 126.2 14.1 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFX88836.1 - 2.2e-25 89.5 0.1 1.6e-24 86.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KFX88836.1 - 1.2e-08 35.3 0.2 9.1e-07 29.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KFX88836.1 - 4.4e-06 25.9 33.5 2e-05 23.7 23.2 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 KFX88836.1 - 0.00041 19.8 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 KFX88836.1 - 0.00051 19.9 18.5 0.13 12.4 2.5 4.3 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_15 PF13175.1 KFX88836.1 - 0.0018 17.3 0.0 0.64 9.0 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KFX88836.1 - 0.004 16.3 0.1 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX88836.1 - 0.0069 15.8 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KFX88836.1 - 0.0088 15.9 0.0 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX88836.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFX88836.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KFX88836.1 - 0.068 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFX88836.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX88836.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KFX88836.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KFX88836.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 KFX88837.1 - 3.8e-38 131.3 0.0 4.9e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFX88837.1 - 3.1e-06 26.5 0.0 5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_MocR PF12897.2 KFX88837.1 - 3.1e-06 26.0 0.0 4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.15 KFX88837.1 - 3.1e-06 25.7 0.0 4.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFX88837.1 - 3.9e-05 22.5 0.0 5.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFX88837.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 KFX88837.1 - 0.0014 17.4 0.2 0.0031 16.2 0.1 1.5 1 1 0 1 1 1 1 Allinase DnaB_2 PF07261.6 KFX88837.1 - 0.014 14.9 0.1 15 5.3 0.0 3.2 3 0 0 3 3 3 0 Replication initiation and membrane attachment RNase_Zc3h12a PF11977.3 KFX88837.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SET PF00856.23 KFX88838.1 - 8.4e-11 42.4 0.2 3.6e-10 40.3 0.1 1.9 1 1 0 1 1 1 1 SET domain NGP1NT PF08153.7 KFX88840.1 - 5e-45 152.6 0.0 8.4e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KFX88840.1 - 3.7e-19 68.7 0.0 6.6e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX88840.1 - 0.00037 19.7 0.0 0.0019 17.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KFX88840.1 - 0.0012 18.0 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 KFX88840.1 - 0.0025 17.6 5.1 0.54 10.0 0.0 4.1 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 KFX88840.1 - 0.0029 17.0 0.0 0.27 10.6 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFX88840.1 - 0.0092 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Nop14 PF04147.7 KFX88840.1 - 0.67 7.7 23.4 0.88 7.4 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family HBS1_N PF08938.5 KFX88840.1 - 0.8 9.8 11.6 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus Daxx PF03344.10 KFX88840.1 - 1 7.7 17.0 1.6 7.1 11.8 1.2 1 0 0 1 1 1 0 Daxx Family AA_permease_2 PF13520.1 KFX88842.1 - 8.2e-65 218.9 26.0 9.5e-65 218.7 18.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX88842.1 - 8.2e-14 50.7 23.5 1.2e-13 50.2 16.3 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydro_lipase PF04083.11 KFX88846.1 - 9.4e-17 60.1 0.0 1.7e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DUF3824 PF12868.2 KFX88846.1 - 0.00077 20.4 3.0 0.0026 18.7 2.1 1.8 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF3328 PF11807.3 KFX88846.1 - 0.041 13.5 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) ADH_N PF08240.7 KFX88847.1 - 7.4e-10 38.5 0.3 2.1e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX88847.1 - 6.6e-06 25.6 0.0 0.00015 21.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFX88847.1 - 0.018 14.7 1.5 0.28 10.8 1.1 2.5 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KFX88847.1 - 0.059 14.2 0.0 0.13 13.1 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Chromo PF00385.19 KFX88849.1 - 0.012 15.2 2.6 0.012 15.2 1.8 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain ORC6 PF05460.8 KFX88850.1 - 0.82 8.7 4.6 1.2 8.2 3.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Erv26 PF04148.8 KFX88851.1 - 1.6e-81 272.6 2.2 1.9e-81 272.4 1.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Methyltransf_11 PF08241.7 KFX88852.1 - 3.1e-10 40.4 0.0 6.5e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.3 KFX88852.1 - 4.6e-10 39.8 2.8 8.2e-10 39.0 1.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.1 KFX88852.1 - 4.1e-06 27.0 0.0 8.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX88852.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX88852.1 - 4.5e-05 23.8 0.3 0.00038 20.8 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 KFX88852.1 - 8.3e-05 22.2 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFX88852.1 - 0.00017 22.1 0.0 0.00037 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX88852.1 - 0.00019 21.1 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX88852.1 - 0.00057 19.0 0.0 0.0012 18.0 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KFX88852.1 - 0.0061 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX88852.1 - 0.0088 15.1 0.0 0.023 13.8 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF1640 PF07798.6 KFX88853.1 - 2.7e-60 203.4 10.1 3.5e-60 203.0 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) OEP PF02321.13 KFX88853.1 - 0.27 10.8 7.6 2.8 7.4 0.3 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein cwf21 PF08312.7 KFX88853.1 - 0.32 10.8 5.5 0.52 10.2 2.7 2.2 2 1 0 2 2 2 0 cwf21 domain Syntaxin PF00804.20 KFX88853.1 - 0.66 10.1 8.1 1.3 9.1 5.0 2.0 1 1 0 1 1 1 0 Syntaxin GTP_EFTU PF00009.22 KFX88854.1 - 1.3e-37 129.0 0.0 2.1e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KFX88854.1 - 1.1e-36 124.6 0.4 2.6e-36 123.5 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KFX88854.1 - 2e-10 40.6 0.5 4.1e-10 39.6 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX88854.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_C12 PF01088.16 KFX88856.1 - 2.8e-61 206.4 0.0 3.2e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CH PF00307.26 KFX88856.1 - 0.028 14.4 0.0 0.93 9.5 0.0 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain DDE_1 PF03184.14 KFX88861.1 - 6e-16 58.2 0.0 1.1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KFX88861.1 - 0.021 14.6 0.2 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_psq PF05225.11 KFX88861.1 - 0.03 13.8 0.4 0.07 12.7 0.3 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 KFX88861.1 - 0.049 13.4 0.0 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain rve PF00665.21 KFX88862.1 - 1.2e-17 64.1 0.0 2.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Trypan_PARP PF05887.6 KFX88862.1 - 0.0019 18.0 10.4 0.19 11.5 1.7 2.5 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) rve_3 PF13683.1 KFX88862.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain LRR_6 PF13516.1 KFX88873.1 - 3.5e-12 45.0 12.4 0.0043 16.9 0.0 8.6 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.2 KFX88873.1 - 2.2e-09 36.8 0.7 1.1e-08 34.5 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFX88873.1 - 1.6e-06 27.6 0.8 5.4e-06 25.9 0.6 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KFX88873.1 - 2.5e-06 26.9 9.0 0.016 14.8 0.2 6.2 3 3 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX88873.1 - 4.9e-05 22.7 14.8 0.2 11.7 0.1 8.3 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 KFX88873.1 - 0.056 13.1 12.9 0.24 11.1 0.1 5.3 5 2 1 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 KFX88873.1 - 0.059 13.5 19.0 11 6.7 0.1 8.9 10 1 1 11 11 11 0 Leucine rich repeat PAH PF02671.16 KFX88876.1 - 1.2e-44 149.6 8.4 7e-18 63.9 0.2 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFX88876.1 - 2.3e-37 126.7 0.0 8e-37 125.0 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Haemolytic PF01809.13 KFX88876.1 - 0.25 10.9 0.1 0.58 9.8 0.1 1.5 1 0 0 1 1 1 0 Haemolytic domain Fasciclin PF02469.17 KFX88877.1 - 1.8e-05 24.7 0.0 3.6e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain FAD_binding_2 PF00890.19 KFX88878.1 - 1.9e-82 277.3 0.1 3e-82 276.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KFX88878.1 - 4.2e-21 74.5 0.4 6.6e-20 70.6 0.0 2.7 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KFX88878.1 - 1.3e-12 47.3 0.8 3.9e-11 42.4 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFX88878.1 - 1.2e-09 37.7 0.2 2.9e-09 36.5 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX88878.1 - 1.1e-07 31.7 2.7 2.6e-07 30.5 0.3 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX88878.1 - 1.2e-07 31.7 0.0 1.3e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX88878.1 - 1.5e-05 24.2 0.4 0.0058 15.7 0.1 2.7 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.9 KFX88878.1 - 0.00031 19.3 4.5 0.0092 14.4 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 KFX88878.1 - 0.0018 17.2 1.8 0.21 10.3 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KFX88878.1 - 0.0038 16.3 0.2 0.34 9.9 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KFX88878.1 - 0.0083 15.9 0.0 0.042 13.6 0.0 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX88878.1 - 0.012 15.6 0.7 0.035 14.1 0.4 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX88878.1 - 0.016 14.2 0.7 0.049 12.6 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.22 KFX88878.1 - 0.16 12.3 3.8 2 8.8 0.4 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_60s PF00428.14 KFX88878.1 - 7.2 7.0 10.9 16 5.9 7.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Glyco_hydro_76 PF03663.9 KFX88879.1 - 3.5e-22 79.3 1.5 1.5e-13 50.9 0.0 3.0 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 zf-DHHC PF01529.15 KFX88880.1 - 2.9e-32 111.4 1.8 5.1e-32 110.6 1.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFX88880.1 - 0.026 14.2 0.9 0.057 13.2 0.6 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily SAPS PF04499.10 KFX88885.1 - 0.11 11.1 1.4 0.21 10.1 0.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Adeno_terminal PF02459.10 KFX88885.1 - 0.36 8.9 2.2 0.53 8.3 1.5 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BUD22 PF09073.5 KFX88885.1 - 0.55 9.2 21.0 0.039 13.0 11.3 1.5 2 0 0 2 2 2 0 BUD22 MgsA_C PF12002.3 KFX88886.1 - 2.3e-58 196.5 0.0 3.6e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KFX88886.1 - 3.1e-12 46.8 0.0 7.3e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX88886.1 - 3.7e-09 35.9 0.0 1.2e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KFX88886.1 - 6.9e-06 25.3 0.1 0.034 13.2 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFX88886.1 - 4e-05 23.2 0.0 0.0001 21.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 KFX88886.1 - 5.3e-05 22.7 0.1 0.0015 18.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KFX88886.1 - 0.00012 21.8 0.1 0.0094 15.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX88886.1 - 0.0011 19.1 0.3 0.0059 16.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX88886.1 - 0.0031 17.5 0.7 0.066 13.2 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.6 KFX88886.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KFX88886.1 - 0.0046 15.7 0.0 0.04 12.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 KFX88886.1 - 0.0089 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 KFX88886.1 - 0.016 15.0 0.1 6.6 6.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 KFX88886.1 - 0.017 13.8 0.1 0.05 12.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFX88886.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFX88886.1 - 0.021 14.8 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFX88886.1 - 0.11 12.0 0.1 0.36 10.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KFX88886.1 - 0.15 11.6 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_hydro_10 PF00331.15 KFX88887.1 - 4.3e-104 347.9 0.0 5e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 KFX88887.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Cellulase-like PF12876.2 KFX88887.1 - 0.13 12.7 0.0 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 Sugar-binding cellulase-like DUF1771 PF08590.5 KFX88903.1 - 3.5e-13 49.3 9.5 3.5e-13 49.3 6.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KFX88903.1 - 1.9e-09 37.5 0.1 1.2e-08 34.9 0.0 2.5 3 0 0 3 3 3 1 Smr domain zf-CCCH PF00642.19 KFX88903.1 - 5.1e-07 29.2 0.6 0.0049 16.5 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KFX88903.1 - 0.00097 19.2 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 HBS1 N-terminus CPSase_L_D2 PF02786.12 KFX88904.1 - 8.7e-82 273.4 0.1 1.5e-81 272.7 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KFX88904.1 - 1.5e-62 210.5 0.0 2.7e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KFX88904.1 - 4.9e-35 119.9 0.0 1.2e-34 118.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFX88904.1 - 4.1e-27 94.2 0.0 5.6e-26 90.6 0.0 2.5 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KFX88904.1 - 1.1e-25 90.6 0.0 2.8e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 KFX88904.1 - 2.9e-20 72.7 0.1 5.6e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFX88904.1 - 1.2e-16 60.0 4.6 4.1e-16 58.3 3.2 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFX88904.1 - 6.9e-16 57.8 0.0 4.2e-15 55.3 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX88904.1 - 2.4e-11 43.4 0.0 4.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KFX88904.1 - 1.3e-08 34.3 2.2 5e-08 32.4 0.3 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 KFX88904.1 - 2.1e-08 33.8 0.1 5.5e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KFX88904.1 - 1e-07 31.4 0.1 2.1e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFX88904.1 - 1.5e-05 24.8 0.2 5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD PF00529.15 KFX88904.1 - 0.001 18.4 1.0 0.0016 17.8 0.0 1.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 KFX88904.1 - 0.0048 16.1 0.7 0.012 14.8 0.2 1.8 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KFX88904.1 - 0.0048 17.2 0.7 0.037 14.3 0.4 2.6 2 1 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 KFX88904.1 - 0.015 14.8 0.0 0.037 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 KFX88904.1 - 0.02 14.6 0.8 0.046 13.4 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Rieske PF00355.21 KFX88904.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Ribosomal_L5_C PF00673.16 KFX88906.1 - 7.5e-22 76.8 0.0 1.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFX88906.1 - 9.7e-21 73.3 0.0 2.3e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 LSM PF01423.17 KFX88907.1 - 5.9e-17 60.9 0.0 7.8e-17 60.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 KFX88907.1 - 0.091 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin MPC PF03650.8 KFX88908.1 - 2.1e-35 121.2 0.0 2.6e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Na_Ca_ex PF01699.19 KFX88909.1 - 2e-48 163.5 29.3 1.1e-26 93.0 3.9 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PDR_CDR PF06422.7 KFX88909.1 - 0.066 12.8 0.0 5.4 6.7 0.0 2.9 2 0 0 2 2 2 0 CDR ABC transporter Vpu PF00558.14 KFX88909.1 - 1.1 8.8 3.8 4.4 6.9 0.0 3.1 3 0 0 3 3 3 0 Vpu protein Cnd2 PF05786.9 KFX88910.1 - 1.9e-225 750.7 1.3 2.4e-225 750.3 0.9 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 MGS PF02142.17 KFX88912.1 - 7.4e-24 83.5 0.0 1.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain AICARFT_IMPCHas PF01808.13 KFX88912.1 - 1.4e-16 60.5 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme DUF1180 PF06679.7 KFX88914.1 - 0.8 9.5 3.0 0.98 9.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MGC-24 PF05283.6 KFX88914.1 - 3.1 7.5 7.1 3.7 7.3 4.9 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Clathrin PF00637.15 KFX88915.1 - 3.4e-209 684.8 41.5 2.7e-35 121.0 2.4 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KFX88915.1 - 7.8e-33 112.1 0.4 4.5e-32 109.7 0.2 2.5 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 KFX88915.1 - 1.1e-30 103.7 0.4 3.1e-05 23.9 0.0 7.7 7 0 0 7 7 7 5 Clathrin propeller repeat TPR_7 PF13176.1 KFX88915.1 - 1.5e-05 24.4 4.9 16 5.5 0.0 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFX88915.1 - 0.00026 20.8 1.2 5.3 7.0 0.0 5.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin-link PF09268.5 KFX88915.1 - 0.00058 18.8 0.6 0.0016 17.4 0.1 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 KFX88915.1 - 0.035 13.7 1.9 12 5.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_3 PF13606.1 KFX88915.1 - 0.05 13.8 0.0 1 9.8 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat TPR_2 PF07719.12 KFX88915.1 - 0.73 9.8 8.4 30 4.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX88915.1 - 1.1 10.0 15.9 17 6.4 0.1 8.7 11 0 0 11 11 11 0 Tetratricopeptide repeat Atg31 PF09795.4 KFX88920.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 31 zf-Apc11 PF12861.2 KFX88921.1 - 2.7e-45 152.1 11.8 3.2e-45 151.8 8.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFX88921.1 - 4.1e-33 113.3 10.9 5.3e-33 112.9 7.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFX88921.1 - 1.7e-08 34.1 16.7 1e-07 31.6 11.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX88921.1 - 3.8e-05 23.2 12.5 0.00085 18.9 8.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX88921.1 - 0.00011 21.7 14.9 0.00047 19.7 10.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX88921.1 - 0.00043 20.2 14.6 0.003 17.5 10.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX88921.1 - 0.00054 19.7 4.7 0.00054 19.7 3.3 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFX88921.1 - 0.0012 18.3 3.1 0.0012 18.3 2.2 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFX88921.1 - 0.0017 18.2 16.8 0.03 14.2 11.7 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 KFX88921.1 - 0.049 13.3 16.7 0.95 9.2 11.9 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 KFX88921.1 - 0.049 13.1 6.5 0.089 12.3 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 KFX88921.1 - 0.06 13.0 4.7 0.062 12.9 0.7 2.3 2 0 0 2 2 2 0 HIT zinc finger Opy2 PF09463.5 KFX88921.1 - 0.11 12.5 10.3 2.2 8.4 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein DUF2256 PF10013.4 KFX88921.1 - 0.12 12.1 0.2 0.12 12.1 0.1 3.5 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Rtf2 PF04641.7 KFX88921.1 - 0.12 11.5 2.0 0.16 11.1 1.4 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger zf-DBF PF07535.7 KFX88921.1 - 0.32 10.7 3.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 DBF zinc finger DUF329 PF03884.9 KFX88921.1 - 1.9 8.1 8.2 0.69 9.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) zinc-ribbons_6 PF07191.7 KFX88921.1 - 3.6 7.4 10.7 1.7 8.4 0.2 2.6 1 1 2 3 3 3 0 zinc-ribbons zf-RING-like PF08746.6 KFX88921.1 - 4 7.5 15.2 20 5.2 10.5 2.1 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 KFX88921.1 - 4.1 7.5 13.1 13 5.9 8.8 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.2 KFX88921.1 - 5.9 6.7 13.8 15 5.5 4.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.1 KFX88921.1 - 7.3 6.8 12.4 4.2 7.5 4.6 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFX88921.1 - 8.2 6.4 11.2 3.5 7.6 4.2 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain PHD PF00628.24 KFX88921.1 - 9.2 6.0 15.7 44 3.8 10.9 2.1 1 1 0 1 1 1 0 PHD-finger Rhodanese PF00581.15 KFX88922.1 - 4.9e-19 68.7 0.0 2.3e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.15 KFX88923.1 - 2.3e-28 97.7 2.1 2.3e-28 97.7 1.4 2.3 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KFX88923.1 - 7.3e-22 76.4 0.0 1.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Cyclin_N PF00134.18 KFX88926.1 - 2.5e-34 117.6 0.4 4.6e-34 116.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFX88926.1 - 8.3e-14 51.5 0.2 2.5e-13 49.9 0.1 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain PIG-U PF06728.8 KFX88932.1 - 1.4e-124 415.8 30.2 1.6e-124 415.6 20.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 KFX88933.1 - 1.6e-110 368.8 0.1 1.6e-110 368.8 0.0 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KFX88933.1 - 2.5e-10 40.3 0.0 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain WLM PF08325.5 KFX88935.1 - 2.5e-47 161.1 0.2 2.5e-47 161.1 0.1 1.8 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 KFX88935.1 - 3.9e-08 33.3 1.1 7.7e-08 32.3 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 YdjO PF14169.1 KFX88935.1 - 3.7 7.0 11.5 4.4 6.8 3.1 3.3 1 1 2 3 3 3 0 Cold-inducible protein YdjO KH_1 PF00013.24 KFX88936.1 - 9.1e-41 137.3 3.7 9.7e-17 60.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFX88936.1 - 3.7e-31 106.2 10.7 4.2e-12 45.4 1.4 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFX88936.1 - 2.6e-12 46.1 4.7 0.0052 16.3 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFX88936.1 - 0.0014 18.2 1.4 3.4 7.3 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KFX88936.1 - 0.015 15.0 6.5 0.87 9.4 0.1 3.1 3 0 0 3 3 3 0 NusA-like KH domain Rsc14 PF08586.5 KFX88937.1 - 0.038 14.4 0.6 6.1 7.3 0.1 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit CENP-K PF11802.3 KFX88938.1 - 1.7e-08 34.0 2.8 0.0005 19.3 0.0 2.9 2 1 1 3 3 3 2 Centromere-associated protein K DUF4446 PF14584.1 KFX88938.1 - 1.1 9.0 4.9 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) BAR PF03114.13 KFX88938.1 - 2.2 7.7 7.9 1.3 8.4 2.9 2.3 2 1 0 2 2 2 0 BAR domain Spectrin PF00435.16 KFX88938.1 - 3.3 8.0 9.0 0.72 10.1 0.6 2.7 2 1 0 2 2 2 0 Spectrin repeat IncA PF04156.9 KFX88938.1 - 6.2 6.3 14.9 0.65 9.5 0.7 2.6 2 1 1 3 3 3 0 IncA protein DUF2458 PF10454.4 KFX88938.1 - 8 6.3 10.3 0.59 10.0 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) Abhydrolase_6 PF12697.2 KFX88939.1 - 4.2e-11 43.1 0.0 1.2e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX88939.1 - 4.6e-08 32.9 0.0 4.5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX88939.1 - 9.2e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX88939.1 - 0.025 13.7 0.0 0.14 11.4 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFX88939.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Kelch_3 PF13415.1 KFX88940.1 - 1.1e-26 92.3 15.2 4e-08 33.2 0.0 7.0 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFX88940.1 - 1.3e-23 82.4 12.1 2.5e-06 27.1 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.1 KFX88940.1 - 2.5e-23 81.7 0.1 2.5e-23 81.7 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 KFX88940.1 - 7.8e-19 66.9 3.7 0.0003 20.8 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFX88940.1 - 1.9e-17 62.8 3.9 1.6e-06 27.9 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KFX88940.1 - 1.5e-14 53.2 0.1 1.4e-05 24.5 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KFX88940.1 - 5.3e-12 45.0 2.7 0.15 11.8 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Proteasome PF00227.21 KFX88941.1 - 7.4e-47 159.0 0.1 9.3e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KFX88941.1 - 7.4e-13 47.5 2.2 1.5e-12 46.5 1.5 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal CTDII PF01556.13 KFX88943.1 - 7.6e-21 73.8 0.1 1e-17 63.8 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KFX88943.1 - 8.2e-20 70.3 1.9 2e-19 69.0 1.3 1.7 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KFX88943.1 - 1.5e-13 50.2 0.0 2.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ_CXXCXGXG PF00684.14 KFX88943.1 - 2.5e-13 49.8 19.5 2.5e-13 49.8 13.5 2.5 2 0 0 2 2 2 1 DnaJ central domain Zn_clus PF00172.13 KFX88943.1 - 3.1e-07 30.1 8.5 3.1e-07 30.1 5.9 3.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KFX88944.1 - 1.7e-06 27.6 0.1 0.27 11.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFX88944.1 - 0.051 13.3 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region URO-D PF01208.12 KFX88946.1 - 9.7e-119 396.2 0.0 1.1e-118 396.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L10 PF00466.15 KFX88947.1 - 4.9e-25 87.3 0.0 1.1e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KFX88947.1 - 4.4e-13 49.4 4.5 1.7e-12 47.5 1.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.16 KFX88948.1 - 1.1e-60 204.9 0.1 1.9e-60 204.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX88948.1 - 1.6e-43 148.8 0.0 5.2e-43 147.2 0.0 1.9 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KFX88948.1 - 1.9e-19 69.7 0.0 5.6e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KFX88948.1 - 2.2e-08 34.2 0.0 5.3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KFX88948.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV FMN_red PF03358.10 KFX88949.1 - 1.5e-10 40.7 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KFX88949.1 - 7.1e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KFX88949.1 - 7.5e-05 22.3 0.0 9.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 KFX88949.1 - 0.13 11.6 0.3 0.64 9.3 0.1 2.1 2 1 0 2 2 2 0 Flavodoxin zf-HC5HC2H_2 PF13832.1 KFX88950.1 - 1.2e-18 67.1 1.6 1.2e-18 67.1 1.1 4.0 4 0 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFX88950.1 - 2.3e-15 56.5 4.1 2.3e-15 56.5 2.8 4.6 4 1 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 KFX88950.1 - 1.8e-12 47.0 0.1 3.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KFX88950.1 - 8.7e-12 44.5 54.5 6.4e-07 28.9 4.6 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 KFX88950.1 - 1.3e-08 33.9 3.5 1.3e-08 33.9 2.4 6.1 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.17 KFX88950.1 - 0.0075 15.9 5.8 0.0075 15.9 4.0 5.7 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 KFX88951.1 - 1.1e-22 78.9 0.0 8e-10 38.2 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 KFX88951.1 - 1.3e-07 30.1 0.2 0.0021 16.2 0.0 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFX88951.1 - 0.016 14.7 0.5 0.14 11.5 0.3 2.1 1 1 0 1 1 1 0 PQQ-like domain Nbas_N PF15492.1 KFX88951.1 - 0.066 12.3 0.0 6 5.8 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Sel1 PF08238.7 KFX88953.1 - 5.6e-14 52.2 7.4 0.0024 18.4 0.2 4.2 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.7 KFX88954.1 - 1.7e-69 233.8 0.1 8.4e-46 156.3 0.0 2.3 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFX88954.1 - 1.1e-33 115.0 0.1 7e-33 112.4 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.15 KFX88955.1 - 6.1e-74 248.5 10.3 1.3e-73 247.4 7.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFX88955.1 - 1.9e-30 104.3 3.3 1.9e-30 104.3 2.3 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFX88955.1 - 1.9e-09 36.9 0.0 3.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain VRR_NUC PF08774.6 KFX88956.1 - 3.2e-19 68.7 0.0 6.8e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain PrkA PF06798.7 KFX88956.1 - 0.02 14.1 0.1 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain ChaB PF06150.7 KFX88956.1 - 0.064 13.0 0.0 0.99 9.2 0.0 2.4 2 0 0 2 2 2 0 ChaB Dpy-30 PF05186.8 KFX88957.1 - 6.1e-15 54.4 0.0 8.9e-15 53.8 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.7 KFX88958.1 - 7.6e-30 102.5 0.0 1.5e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KFX88958.1 - 5.3e-22 77.3 0.0 8.6e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KFX88958.1 - 0.02 14.6 0.2 0.043 13.5 0.0 1.6 2 1 0 2 2 2 0 'Paired box' domain RabGAP-TBC PF00566.13 KFX88959.1 - 2.5e-31 108.8 0.0 4.2e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF4072 PF13284.1 KFX88959.1 - 0.27 11.4 1.9 1.8 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) 7tm_2 PF00002.19 KFX88960.1 - 2.5e-05 23.4 17.8 4.1e-05 22.7 10.7 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) OGG_N PF07934.7 KFX88961.1 - 1.5e-35 121.6 0.0 3.2e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KFX88961.1 - 1.9e-14 53.8 0.0 3.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFX88961.1 - 0.00017 21.0 0.0 0.00048 19.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 KFX88962.1 - 3.7e-31 106.5 0.6 4.6e-12 45.4 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88962.1 - 1.3e-22 79.5 0.0 2.9e-06 27.1 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88962.1 - 3.5e-19 68.4 0.0 3.6e-08 33.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 KFX88962.1 - 0.012 15.6 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family SF3b1 PF08920.5 KFX88963.1 - 7.4e-40 136.3 0.8 7.4e-40 136.3 0.6 2.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KFX88963.1 - 1.5e-14 54.0 2.5 0.011 16.0 0.0 7.4 6 2 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 KFX88963.1 - 4.6e-11 42.8 1.3 0.34 11.4 0.0 7.8 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 KFX88963.1 - 1e-09 37.6 9.2 1 9.6 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KFX88963.1 - 3e-05 24.3 0.4 0.69 10.3 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KFX88963.1 - 0.00022 19.7 0.3 0.069 11.4 0.0 3.0 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 KFX88963.1 - 0.0073 15.6 0.1 5.4 6.3 0.0 3.7 3 0 0 3 3 3 1 NUC173 domain UPF0236 PF06782.6 KFX88963.1 - 0.011 14.1 0.1 0.02 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) CLASP_N PF12348.3 KFX88963.1 - 0.017 14.4 0.1 0.92 8.8 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal Rho_N PF07498.7 KFX88966.1 - 0.0013 18.3 0.2 0.89 9.3 0.0 3.3 3 0 0 3 3 3 2 Rho termination factor, N-terminal domain SAP PF02037.22 KFX88966.1 - 0.12 11.9 1.1 26 4.4 0.2 3.8 3 1 0 3 3 3 0 SAP domain F-box-like PF12937.2 KFX88969.1 - 0.001 18.7 0.0 0.003 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like Solute_trans_a PF03619.11 KFX88971.1 - 7.1e-40 137.0 11.0 1e-39 136.5 7.7 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha YycC PF14174.1 KFX88971.1 - 0.42 10.3 2.5 0.78 9.4 0.8 2.0 2 0 0 2 2 2 0 YycC-like protein DUF3720 PF12517.3 KFX88974.1 - 0.033 14.8 0.3 0.043 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Jiraiya PF15038.1 KFX88974.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Jiraiya Mad3_BUB1_I PF08311.7 KFX88988.1 - 4.5e-41 139.5 0.0 9.5e-41 138.5 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KFX88988.1 - 2.8e-12 46.3 0.0 5.6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88988.1 - 0.0036 16.4 0.0 0.011 14.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SpaB_C PF14028.1 KFX88988.1 - 0.012 15.1 2.6 0.029 13.9 1.8 1.6 1 0 0 1 1 1 0 SpaB C-terminal domain APH PF01636.18 KFX88988.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KFX88988.1 - 0.074 12.1 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3K_1B_p101 PF10486.4 KFX88988.1 - 1.1 6.6 8.4 0.69 7.4 4.4 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Indigoidine_A PF04227.7 KFX88989.1 - 1.3e-114 382.3 0.5 2e-114 381.7 0.3 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KFX88989.1 - 6.6e-14 51.7 4.5 3.9e-07 29.5 0.0 3.0 3 0 0 3 3 3 2 pfkB family carbohydrate kinase UCH PF00443.24 KFX88992.1 - 2.5e-26 92.3 0.0 4.3e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFX88992.1 - 8.7e-24 83.4 16.0 3e-19 68.8 2.1 3.5 3 1 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KFX88992.1 - 1.7e-08 34.0 0.2 4.7e-08 32.6 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UCH_1 PF13423.1 KFX88992.1 - 7.2e-08 32.2 0.0 1.7e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2180 PF09947.4 KFX88992.1 - 9.5 6.0 15.8 2.3 8.0 0.2 4.2 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2180) DEAD PF00270.24 KFX88993.1 - 9.2e-51 171.6 0.0 5.7e-49 165.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase NifU_N PF01592.11 KFX88993.1 - 7e-50 168.2 0.0 1.3e-49 167.3 0.0 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain Helicase_C PF00271.26 KFX88993.1 - 1.9e-28 98.1 0.0 7.9e-28 96.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX88993.1 - 3.6e-09 36.7 0.2 1.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFX88993.1 - 8.1e-09 34.6 0.0 1.3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.1 KFX88993.1 - 0.022 13.8 0.0 0.022 13.8 0.0 2.5 2 1 0 2 2 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KFX88993.1 - 0.1 10.9 0.0 0.37 9.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1253) DUF2201_N PF13203.1 KFX88993.1 - 0.37 9.9 7.5 0.61 9.2 5.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 KFX88993.1 - 2.3 5.8 4.6 3.1 5.3 3.2 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 KFX88993.1 - 3.4 7.4 13.8 5.7 6.7 9.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 KFX88993.1 - 6.3 4.7 8.7 8.6 4.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Rft-1 PF04506.8 KFX88994.1 - 1.6e-92 310.6 18.1 1.8e-92 310.5 12.5 1.0 1 0 0 1 1 1 1 Rft protein Med25_SD1 PF11235.3 KFX88995.1 - 1.7 8.9 9.2 0.08 13.2 0.5 2.3 1 1 1 2 2 2 0 Mediator complex subunit 25 synapsin 1 Membralin PF09746.4 KFX88995.1 - 4.6 6.1 8.4 6.1 5.7 5.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein OST3_OST6 PF04756.8 KFX88996.1 - 3.2e-21 75.5 1.1 4.4e-21 75.1 0.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family DUF2157 PF09925.4 KFX88996.1 - 0.043 13.4 0.6 0.11 12.0 0.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) VIT1 PF01988.14 KFX88996.1 - 7.4 5.9 9.4 4 6.8 1.2 2.2 1 1 1 2 2 2 0 VIT family FtsJ PF01728.14 KFX88997.1 - 2.7e-63 213.2 0.0 3.3e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KFX88997.1 - 4e-05 23.3 0.0 7.2e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX88997.1 - 0.0011 19.5 0.0 0.0031 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX88997.1 - 0.0076 15.8 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ceramidase_alk PF04734.8 KFX88998.1 - 7.2e-271 899.9 0.0 8.2e-271 899.7 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF2244 PF10003.4 KFX88998.1 - 0.29 10.4 1.3 0.55 9.6 0.9 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) EMP24_GP25L PF01105.19 KFX89007.1 - 1.3e-40 139.1 0.1 1.6e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pyr_redox_2 PF07992.9 KFX89009.1 - 1.2e-16 61.2 0.0 3.2e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX89009.1 - 3.4e-11 43.3 4.8 7e-09 35.9 0.3 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX89009.1 - 5.2e-06 25.6 7.6 0.083 11.7 0.1 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX89009.1 - 7.2e-06 26.1 0.5 0.0015 18.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX89009.1 - 0.0042 17.0 0.3 1.4 8.9 0.2 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX89009.1 - 0.029 13.2 2.1 0.14 10.9 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KFX89009.1 - 0.032 14.0 2.0 12 5.6 0.0 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KFX89009.1 - 0.094 12.7 0.4 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.1 KFX89009.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFX89009.1 - 0.19 10.5 3.5 3.9 6.2 0.1 3.5 4 0 0 4 4 4 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFX89009.1 - 0.6 8.6 3.7 2.6 6.5 0.1 2.8 3 1 0 3 3 3 0 Tryptophan halogenase Pyridoxal_deC PF00282.14 KFX89010.1 - 3.8e-71 239.5 0.0 3.3e-70 236.4 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFX89010.1 - 0.00065 18.5 0.0 0.00099 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF1212 PF06738.7 KFX89016.1 - 9.8e-59 198.0 5.6 1.2e-53 181.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KFX89016.1 - 5.6e-32 110.4 6.5 5.6e-32 110.4 4.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Aldedh PF00171.17 KFX89017.1 - 9.6e-160 531.8 0.4 1.1e-159 531.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KFX89018.1 - 7.3e-50 169.7 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX89018.1 - 3.9e-38 130.9 0.0 6.4e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX89018.1 - 1.7e-06 27.2 0.0 0.0008 18.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX89018.1 - 0.00015 21.6 0.1 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX89018.1 - 0.00029 19.8 0.0 0.096 11.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFX89018.1 - 0.0009 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX89018.1 - 0.015 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX89018.1 - 0.017 14.1 0.0 0.49 9.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX89018.1 - 0.066 13.6 0.1 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX89018.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Lactonase PF10282.4 KFX89019.1 - 2.5e-23 82.7 0.1 2.2e-08 33.6 0.0 4.2 1 1 3 4 4 4 4 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KFX89019.1 - 0.001 18.4 0.1 0.51 9.6 0.0 3.1 2 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Proteasome_A_N PF10584.4 KFX89019.1 - 0.019 14.3 0.0 4.3 6.7 0.0 2.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Rop-like PF05082.8 KFX89020.1 - 0.00064 19.1 0.9 0.00092 18.6 0.1 1.6 2 0 0 2 2 2 1 Rop-like DUF972 PF06156.8 KFX89020.1 - 0.0087 16.3 0.2 0.01 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Taxilin PF09728.4 KFX89020.1 - 0.014 14.5 0.9 0.016 14.2 0.6 1.0 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ATP-synt_D PF01813.12 KFX89020.1 - 0.023 14.2 1.0 0.027 14.0 0.6 1.3 1 1 0 1 1 1 0 ATP synthase subunit D DUF1640 PF07798.6 KFX89020.1 - 0.027 14.5 0.9 0.035 14.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CALCOCO1 PF07888.6 KFX89020.1 - 0.031 12.5 0.7 0.035 12.4 0.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2067 PF09840.4 KFX89020.1 - 0.043 13.3 0.2 0.049 13.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Seryl_tRNA_N PF02403.17 KFX89020.1 - 0.045 13.7 0.1 0.086 12.8 0.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KFX89020.1 - 0.046 12.3 1.1 0.051 12.2 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 KFX89020.1 - 0.092 11.6 0.4 0.09 11.6 0.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 KFX89020.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 KFX89020.1 - 0.57 9.6 3.4 0.67 9.4 0.6 1.9 1 1 1 2 2 2 0 Septum formation initiator HC2 PF07382.6 KFX89022.1 - 4.9e-05 23.2 23.3 7.8e-05 22.6 16.1 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 HTH_18 PF12833.2 KFX89022.1 - 0.014 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4407 PF14362.1 KFX89022.1 - 3 6.7 16.7 5.2 5.9 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3987 PF13148.1 KFX89022.1 - 4.3 5.8 19.8 8.2 4.8 13.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3708 PF12501.3 KFX89022.1 - 7.8 6.3 5.8 18 5.1 4.0 1.7 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter AAA_34 PF13872.1 KFX89025.1 - 0.019 13.7 0.2 0.025 13.3 0.1 1.1 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SIR2 PF02146.12 KFX89036.1 - 3.9e-59 199.3 0.0 7.1e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KFX89036.1 - 4.5e-05 23.0 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KFX89036.1 - 0.075 12.7 0.2 6.3 6.5 0.1 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FUSC_2 PF13515.1 KFX89037.1 - 5.7e-10 39.2 26.4 9.8e-08 31.9 5.6 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 KFX89037.1 - 7e-08 31.6 7.0 8e-06 24.9 0.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KFX89037.1 - 4.9e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KFX89037.1 - 7.3e-06 24.8 1.9 7.3e-06 24.8 1.3 2.1 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.7 KFX89037.1 - 0.00024 19.7 9.2 0.00024 19.7 6.4 3.1 3 0 0 3 3 3 2 Fusaric acid resistance protein family Bac_export_1 PF01311.15 KFX89037.1 - 0.027 13.7 1.4 0.1 11.8 0.5 2.1 2 0 0 2 2 2 0 Bacterial export proteins, family 1 adh_short PF00106.20 KFX89038.1 - 8.7e-34 116.8 2.7 1e-33 116.6 1.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX89038.1 - 5.4e-24 85.2 0.0 6.1e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX89038.1 - 7.5e-16 58.3 1.7 1.1e-15 57.7 1.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX89038.1 - 3.2e-07 30.5 0.5 5.7e-07 29.7 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX89038.1 - 0.00046 19.7 0.0 0.084 12.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFX89038.1 - 0.00053 19.2 0.0 0.00073 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KFX89038.1 - 0.0023 17.0 0.1 0.0048 15.9 0.0 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KFX89038.1 - 0.0058 16.7 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KFX89038.1 - 0.0064 16.2 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_3 PF01494.14 KFX89038.1 - 0.072 12.1 0.2 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_6 PF12697.2 KFX89042.1 - 4.8e-22 78.9 0.1 6.1e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX89042.1 - 1.4e-11 44.4 0.1 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX89042.1 - 1.1e-08 34.9 0.0 2.3e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFX89042.1 - 0.027 12.9 0.0 0.043 12.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Cupin_2 PF07883.6 KFX89043.1 - 5.5e-09 35.3 1.0 1.1e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KFX89043.1 - 0.0055 16.4 0.1 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 KFX89043.1 - 0.039 13.8 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family MannoseP_isomer PF01050.13 KFX89043.1 - 0.04 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DUF3181 PF11378.3 KFX89043.1 - 0.1 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Bac_rhamnosid PF05592.6 KFX89044.1 - 5.1e-15 54.6 0.0 4.6e-06 25.1 0.0 3.3 3 1 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFX89044.1 - 0.025 13.2 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Cyclin_N PF00134.18 KFX89048.1 - 4.2e-42 142.7 0.0 7.4e-42 141.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFX89048.1 - 2.4e-33 114.5 0.0 5.8e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.22 KFX89049.1 - 6.8e-75 246.8 0.9 7.1e-26 89.7 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KFX89049.1 - 4.5e-16 56.8 7.1 4.5e-07 28.7 0.1 5.8 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KFX89049.1 - 1e-14 53.0 6.1 5.8e-07 28.8 0.1 6.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 KFX89049.1 - 1.5e-14 53.8 5.6 6.1e-08 32.6 0.6 3.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KFX89049.1 - 1.5e-10 39.8 3.1 1.2e-05 24.4 0.2 4.5 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KFX89049.1 - 3.8e-10 39.2 7.7 0.081 12.5 0.1 5.7 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_9 PF14658.1 KFX89049.1 - 0.11 12.3 0.0 14 5.6 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain EF-hand_4 PF12763.2 KFX89049.1 - 0.21 11.3 0.2 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.7 KFX89049.1 - 0.25 11.6 2.8 9.6 6.4 1.6 3.2 1 1 0 1 1 1 0 p25-alpha Metallophos PF00149.23 KFX89058.1 - 4.6e-42 143.6 0.9 6.6e-42 143.1 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase P16-Arc PF04699.9 KFX89058.1 - 0.2 11.6 0.3 0.44 10.5 0.2 1.5 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) PsbN PF02468.10 KFX89071.1 - 0.008 15.7 0.1 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Photosystem II reaction centre N protein (psbN) TctB PF07331.6 KFX89071.1 - 0.061 12.9 1.3 1.2 8.7 0.9 2.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family FAD_binding_3 PF01494.14 KFX89072.1 - 5.3e-79 265.8 0.0 6.8e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KFX89072.1 - 3.5e-48 163.4 0.0 6.4e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 KFX89072.1 - 1.1e-05 24.4 0.2 0.00043 19.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFX89072.1 - 1.9e-05 23.9 0.2 3.7e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFX89072.1 - 0.0003 19.8 0.5 0.011 14.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFX89072.1 - 0.00095 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFX89072.1 - 0.0023 17.8 0.0 0.0078 16.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX89072.1 - 0.011 14.3 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.5 KFX89072.1 - 0.047 12.5 0.0 5.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 KFX89072.1 - 0.078 13.0 0.3 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain CBM_1 PF00734.13 KFX89073.1 - 1.6e-09 37.2 13.7 1.6e-09 37.2 9.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain GMC_oxred_N PF00732.14 KFX89075.1 - 2.1e-09 36.9 0.0 8.5e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX89075.1 - 2.2e-08 34.5 0.2 6.1e-06 26.5 0.1 2.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX89075.1 - 2.8e-05 23.1 0.3 4.3e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFX89075.1 - 0.00028 20.1 0.3 0.00044 19.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Abhydrolase_6 PF12697.2 KFX89075.1 - 0.0012 18.7 0.0 0.0064 16.3 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family NAD_binding_8 PF13450.1 KFX89075.1 - 0.0018 18.2 0.7 0.0065 16.4 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX89075.1 - 0.0058 15.5 0.2 0.015 14.1 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX89075.1 - 0.019 14.8 0.1 0.04 13.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX89075.1 - 0.025 13.4 0.1 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFX89075.1 - 0.061 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFX89075.1 - 0.09 11.2 0.1 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF900 PF05990.7 KFX89075.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) TPPK_C PF12555.3 KFX89077.1 - 6 6.6 6.8 8.8 6.1 4.7 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal HET PF06985.6 KFX89081.1 - 6.3e-22 78.2 9.0 2.8e-19 69.6 0.0 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 KFX89082.1 - 7.6e-103 344.4 26.9 9.4e-103 344.1 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89082.1 - 1e-21 77.0 33.7 4e-14 52.1 7.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFX89082.1 - 1.2 7.0 14.5 0.84 7.6 1.6 3.4 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Epimerase PF01370.16 KFX89083.1 - 3.5e-15 56.0 0.0 6.8e-15 55.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX89083.1 - 1e-11 44.2 0.0 2.4e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFX89083.1 - 1.5e-09 38.1 0.0 6.8e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX89083.1 - 1e-05 24.4 0.0 1.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX89083.1 - 0.0034 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX89083.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 KFX89083.1 - 0.037 13.2 0.0 0.081 12.1 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.12 KFX89083.1 - 0.053 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_binding_3 PF01494.14 KFX89084.1 - 3e-19 69.3 2.0 6.8e-13 48.3 0.2 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX89084.1 - 7e-07 28.4 0.0 0.016 14.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFX89084.1 - 7.1e-05 22.0 0.2 0.00088 18.4 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFX89084.1 - 0.00015 21.7 0.1 0.00057 19.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX89084.1 - 0.00046 20.5 0.2 0.39 11.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX89084.1 - 0.002 17.0 2.2 0.0085 14.9 0.3 2.5 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 KFX89084.1 - 0.0027 16.6 0.2 0.51 9.1 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 KFX89084.1 - 0.0044 15.5 0.2 1.6 7.0 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 KFX89084.1 - 0.0063 16.3 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX89084.1 - 0.03 14.3 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX89084.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 KFX89085.1 - 9.6e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89085.1 - 9e-06 26.2 0.1 0.00029 21.3 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89085.1 - 0.0004 19.9 0.0 0.0075 15.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX89085.1 - 0.0011 19.3 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89085.1 - 0.0022 18.4 0.1 0.04 14.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX89085.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 KFX89085.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.8 3 0 0 3 3 3 0 Methyltransferase small domain DUF1682 PF07946.9 KFX89087.1 - 5e-95 318.0 0.0 5.8e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) NAD_binding_10 PF13460.1 KFX89090.1 - 5e-10 39.6 0.1 8.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX89090.1 - 5.9e-06 25.8 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX89090.1 - 6.6e-06 25.5 0.0 7.1e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KFX89090.1 - 0.00015 21.7 0.0 0.00041 20.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFX89090.1 - 0.00037 19.4 0.0 0.22 10.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 KFX89090.1 - 0.0069 16.0 0.2 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 KFX89090.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFX89090.1 - 0.093 11.4 0.0 0.46 9.1 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.27 KFX89091.1 - 2.7e-61 201.4 21.3 1e-10 41.0 0.2 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KFX89091.1 - 6e-12 45.0 0.3 1.2e-11 44.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX89091.1 - 1.2e-09 37.5 0.2 4.1e-09 35.8 0.1 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KFX89091.1 - 1.2e-09 36.8 9.2 0.019 13.1 0.1 5.4 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX89091.1 - 0.011 14.5 1.5 1.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like PRANC PF09372.5 KFX89091.1 - 0.035 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Peptidase_M14 PF00246.19 KFX89092.1 - 2.8e-63 214.1 0.0 3.4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sulfatase PF00884.18 KFX89096.1 - 1.1e-52 179.1 0.0 1.5e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KFX89096.1 - 2e-21 75.5 0.3 4.8e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KFX89096.1 - 3.7e-08 33.0 0.3 3.7e-08 33.0 0.2 2.5 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFX89096.1 - 0.013 14.9 0.0 0.085 12.2 0.0 2.1 2 1 0 2 2 2 0 Metalloenzyme superfamily NAD_binding_10 PF13460.1 KFX89097.1 - 3.3e-11 43.5 0.9 4.7e-11 43.0 0.2 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KFX89097.1 - 7.8e-07 28.5 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KFX89097.1 - 0.0029 17.5 1.1 0.027 14.3 0.4 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KFX89097.1 - 0.0056 16.1 0.1 0.017 14.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 KFX89097.1 - 0.0067 16.6 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX89097.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 KFX89098.1 - 1.4e-13 50.8 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89098.1 - 2e-08 33.9 0.0 1.1e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89098.1 - 8.4e-08 32.7 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX89098.1 - 2.6e-07 31.0 0.0 1.1e-06 28.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89098.1 - 3.4e-06 27.4 0.0 1e-05 25.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFX89098.1 - 0.046 12.4 0.0 0.22 10.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KFX89098.1 - 0.057 12.5 0.0 0.89 8.6 0.0 2.2 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KFX89098.1 - 0.17 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Fringe PF02434.11 KFX89102.1 - 0.00017 20.9 0.1 0.0031 16.7 0.3 2.7 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 KFX89102.1 - 0.0093 15.6 1.0 0.021 14.5 0.7 1.5 1 0 0 1 1 1 1 PAN domain GST_C PF00043.20 KFX89103.1 - 1.3e-05 25.0 0.0 7.2e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX89103.1 - 4.5e-05 23.2 0.0 7.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LAGLIDADG_2 PF03161.8 KFX89103.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family GST_N_3 PF13417.1 KFX89104.1 - 5.6e-13 48.9 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX89104.1 - 1.9e-09 37.3 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX89104.1 - 8e-06 25.9 0.0 3.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX89104.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX89104.1 - 0.015 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF913 PF06025.7 KFX89105.1 - 1.3e-126 422.4 0.0 1.3e-126 422.4 0.0 3.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.20 KFX89105.1 - 7.7e-97 324.2 0.0 1.5e-96 323.3 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 KFX89105.1 - 2.1e-85 286.9 0.8 2.1e-85 286.9 0.6 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KFX89105.1 - 3.5e-28 97.6 6.3 3.5e-28 97.6 4.4 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) RabGAP-TBC PF00566.13 KFX89106.1 - 1.5e-46 158.5 0.0 3.9e-45 153.9 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 KFX89106.1 - 0.07 12.9 12.8 0.054 13.3 2.4 3.0 2 1 1 3 3 3 0 Microtubule associated DUF972 PF06156.8 KFX89106.1 - 1.1 9.6 16.2 3.8 7.9 2.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 KFX89106.1 - 3.5 7.3 32.2 13 5.5 2.3 3.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 KFX89106.1 - 9 6.1 19.4 12 5.8 7.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CBS PF00571.23 KFX89107.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 CBS domain DUF1674 PF07896.7 KFX89111.1 - 4.9e-16 58.6 3.9 4.9e-16 58.6 2.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Pribosyltran_N PF13793.1 KFX89112.1 - 1.3e-42 144.2 0.7 7.7e-42 141.6 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KFX89112.1 - 3.6e-42 144.1 2.1 1.3e-33 116.3 0.9 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KFX89112.1 - 6.7e-13 48.4 1.0 3.2e-12 46.2 0.4 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFX89112.1 - 0.0014 17.8 0.2 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 KFX89112.1 - 0.08 12.4 0.1 0.59 9.6 0.1 2.2 1 1 0 1 1 1 0 DUF218 domain His_Phos_1 PF00300.17 KFX89112.1 - 0.13 12.3 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Ribosomal_S6e PF01092.14 KFX89113.1 - 5.8e-63 210.2 0.4 1.3e-62 209.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Ctf8 PF09696.5 KFX89114.1 - 4e-36 123.4 0.0 4.7e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Ctf8 PPTA PF01239.17 KFX89115.1 - 2.9e-29 99.1 11.9 3.8e-07 29.1 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat WD40 PF00400.27 KFX89116.1 - 3.3e-08 33.0 10.5 2.5e-06 27.1 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat OPT PF03169.10 KFX89119.1 - 8.4e-187 622.3 28.8 1.1e-186 622.0 20.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_7 PF00840.15 KFX89124.1 - 1.4e-204 679.3 19.8 1.7e-204 679.1 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_21 PF03370.8 KFX89126.1 - 6.6e-34 116.2 3.2 1.2e-33 115.4 2.2 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Acyltransferase PF01553.16 KFX89127.1 - 2.3e-32 111.1 0.0 4.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SNO PF01174.14 KFX89129.1 - 8.2e-56 188.6 0.0 4.7e-46 156.8 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KFX89129.1 - 7.1e-10 38.6 0.0 7.6e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KFX89129.1 - 6.7e-05 22.4 0.0 0.069 12.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KFX89129.1 - 0.00088 18.7 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFX89129.1 - 0.001 18.3 0.1 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase PX PF00787.19 KFX89130.1 - 1.2e-18 66.9 0.0 3.2e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFX89130.1 - 4.5e-15 55.5 5.1 5.5e-09 35.6 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like DUF1675 PF07897.6 KFX89130.1 - 0.43 10.4 5.9 0.057 13.2 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Acyltransferase PF01553.16 KFX89131.1 - 3.9e-12 45.7 0.0 4.7e-11 42.2 0.0 2.4 2 1 0 2 2 2 1 Acyltransferase Zwint PF15556.1 KFX89135.1 - 0.0088 15.3 5.0 0.011 15.0 3.5 1.1 1 0 0 1 1 1 1 ZW10 interactor Filament PF00038.16 KFX89135.1 - 0.034 13.6 5.7 0.044 13.2 3.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein SPATA24 PF15175.1 KFX89135.1 - 0.041 13.5 3.8 0.075 12.7 0.4 2.4 1 1 2 3 3 3 0 Spermatogenesis-associated protein 24 Sec8_exocyst PF04048.9 KFX89135.1 - 0.11 12.1 0.2 0.2 11.3 0.1 1.4 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain APG6 PF04111.7 KFX89135.1 - 0.12 11.3 3.6 0.15 11.0 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Hemerythrin PF01814.18 KFX89135.1 - 0.23 11.6 2.4 0.66 10.1 0.8 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF3584 PF12128.3 KFX89135.1 - 0.25 8.6 12.1 0.54 7.5 8.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) AATF-Che1 PF13339.1 KFX89135.1 - 0.41 10.8 5.2 0.44 10.7 2.2 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Uds1 PF15456.1 KFX89135.1 - 3.8 7.5 7.6 3.1 7.7 2.6 2.0 1 1 1 2 2 2 0 Up-regulated During Septation DivIC PF04977.10 KFX89136.1 - 0.0015 17.9 8.8 0.024 14.1 2.9 2.4 2 0 0 2 2 2 2 Septum formation initiator DUF904 PF06005.7 KFX89136.1 - 0.11 12.8 4.2 2.9 8.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 KFX89136.1 - 0.24 11.4 7.7 4.2 7.4 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.6 KFX89136.1 - 0.39 10.6 2.0 11 6.0 0.0 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.1 KFX89136.1 - 0.55 9.1 6.5 0.21 10.4 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Rab5-bind PF09311.6 KFX89136.1 - 0.85 9.4 8.7 0.7 9.7 0.2 2.7 3 0 0 3 3 3 0 Rabaptin-like protein DUF2508 PF10704.4 KFX89136.1 - 1.6 8.9 5.4 0.34 11.1 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) HALZ PF02183.13 KFX89136.1 - 1.8 8.3 8.7 7.6 6.3 1.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 KFX89136.1 - 2.2 8.1 9.3 14 5.5 0.3 2.6 2 0 0 2 2 2 0 Basic region leucine zipper RPA_interact_M PF14767.1 KFX89136.1 - 4.4 8.1 7.8 2.4 8.9 2.6 2.4 2 0 0 2 2 2 0 Replication protein A interacting middle ACC_central PF08326.7 KFX89137.1 - 5.1e-267 887.6 0.0 6.3e-267 887.3 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KFX89137.1 - 2.6e-179 596.7 0.0 3.4e-179 596.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KFX89137.1 - 8e-52 175.5 0.0 1.5e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KFX89137.1 - 4.6e-24 84.6 0.1 9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFX89137.1 - 3.4e-21 75.2 0.0 8.1e-19 67.5 0.0 3.8 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KFX89137.1 - 5.2e-17 61.2 0.1 1.7e-16 59.6 0.1 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KFX89137.1 - 2.5e-10 40.4 0.0 7.4e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX89137.1 - 8e-08 31.3 0.0 0.00089 18.0 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX89137.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KFX89137.1 - 0.018 14.9 0.0 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 KFX89137.1 - 0.028 13.7 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFX89137.1 - 0.06 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like NUDE_C PF04880.8 KFX89138.1 - 3.1e-20 73.1 0.9 3.1e-20 73.1 0.6 4.1 2 1 2 4 4 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 KFX89138.1 - 0.0037 15.7 22.3 0.0058 15.1 15.4 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 KFX89138.1 - 0.059 13.2 30.2 1.3 8.9 13.4 4.2 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 KFX89138.1 - 0.28 10.7 30.6 0.038 13.5 7.6 2.9 2 1 1 3 3 3 0 IncA protein ATG16 PF08614.6 KFX89138.1 - 0.34 10.6 23.4 0.69 9.7 8.9 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DDE_Tnp_IS66 PF03050.9 KFX89138.1 - 1.4 8.1 6.0 3.1 6.9 4.2 1.5 1 0 0 1 1 1 0 Transposase IS66 family AAA_13 PF13166.1 KFX89138.1 - 1.6 7.0 16.0 2.8 6.2 11.1 1.3 1 0 0 1 1 1 0 AAA domain Cep57_MT_bd PF06657.8 KFX89138.1 - 2.3 8.1 9.9 9.6 6.2 0.2 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 WXG100 PF06013.7 KFX89138.1 - 4.8 7.2 12.0 43 4.1 3.6 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF904 PF06005.7 KFX89138.1 - 5.6 7.3 27.0 0.15 12.3 2.6 4.0 2 1 3 5 5 5 0 Protein of unknown function (DUF904) DUF3584 PF12128.3 KFX89138.1 - 7.9 3.6 21.4 12 3.0 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KFX89138.1 - 8.1 5.8 27.2 8.8 5.6 17.2 2.1 2 1 0 2 2 2 0 Intermediate filament protein FlxA PF14282.1 KFX89138.1 - 8.4 6.4 15.5 0.89 9.5 3.4 3.1 3 1 0 3 3 3 0 FlxA-like protein CENP-F_leu_zip PF10473.4 KFX89138.1 - 9.9 6.0 31.9 0.43 10.4 4.7 3.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MBA1 PF07961.6 KFX89139.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein MARVEL PF01284.18 KFX89139.1 - 0.15 11.8 19.6 0.25 11.1 12.3 2.3 2 1 0 2 2 2 0 Membrane-associating domain RabGAP-TBC PF00566.13 KFX89140.1 - 2.4e-26 92.5 0.0 4.1e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_28 PF03033.15 KFX89140.1 - 8.4e-19 67.7 0.0 2.9e-18 65.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX89140.1 - 7.9e-07 27.9 0.0 1.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFX89140.1 - 0.025 14.2 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain TLD PF07534.11 KFX89143.1 - 5.6e-23 81.4 0.0 7.7e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 TLD TPR_11 PF13414.1 KFX89144.1 - 2.2e-05 24.0 0.3 0.00012 21.5 0.2 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFX89144.1 - 2.7e-05 23.7 1.7 0.019 14.8 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KFX89144.1 - 0.00013 22.0 0.1 0.00069 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_16 PF13432.1 KFX89144.1 - 0.00015 22.3 2.3 0.044 14.4 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.7 KFX89144.1 - 0.00036 20.2 0.0 0.00096 18.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 KFX89144.1 - 0.00048 19.7 0.4 1.2 9.0 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX89144.1 - 0.0089 16.3 3.1 0.086 13.1 0.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX89144.1 - 0.058 13.3 0.2 27 4.7 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX89144.1 - 0.083 12.5 0.7 7.2 6.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3435 PF11917.3 KFX89146.1 - 1.9e-05 23.5 0.0 2.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) UBN2 PF14223.1 KFX89146.1 - 0.025 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Glyco_hydro_43 PF04616.9 KFX89152.1 - 6.7e-13 48.3 0.0 9e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Mur_ligase_M PF08245.7 KFX89154.1 - 1.3e-06 28.5 0.0 5.3e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Porphobil_deam PF01379.15 KFX89156.1 - 1.1e-14 53.8 0.0 1.2e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain DUF1409 PF07197.7 KFX89156.1 - 0.04 13.9 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Pectinesterase PF01095.14 KFX89159.1 - 1.2e-38 132.4 8.6 1.6e-38 131.9 6.0 1.1 1 0 0 1 1 1 1 Pectinesterase DUF2430 PF10353.4 KFX89159.1 - 0.062 13.4 0.0 5.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Ribosomal_L28e PF01778.12 KFX89159.1 - 0.13 12.6 1.1 0.24 11.8 0.8 1.3 1 0 0 1 1 1 0 Ribosomal L28e protein family MFS_1 PF07690.11 KFX89160.1 - 1.5e-37 129.1 47.8 3.5e-37 127.9 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89160.1 - 2.4e-05 23.1 19.9 0.00038 19.1 13.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter S-antigen PF05756.6 KFX89160.1 - 0.48 10.4 3.0 1.2 9.1 2.1 1.7 1 0 0 1 1 1 0 S-antigen protein Yippee-Mis18 PF03226.9 KFX89163.1 - 5.6e-22 77.6 1.1 6.4e-22 77.4 0.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 KFX89163.1 - 0.017 15.2 1.2 3.9 7.7 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger DUF2039 PF10217.4 KFX89163.1 - 0.046 13.7 1.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) GFA PF04828.9 KFX89163.1 - 0.052 13.4 1.5 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF3268 PF11672.3 KFX89163.1 - 0.069 13.2 2.0 0.72 9.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) Endonuclease_7 PF02945.10 KFX89163.1 - 0.098 12.3 1.4 0.37 10.5 1.0 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII DZR PF12773.2 KFX89163.1 - 0.11 12.3 1.2 0.6 9.9 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Mcm10 PF09332.6 KFX89163.1 - 0.16 11.3 1.1 0.21 10.8 0.7 1.3 1 1 0 1 1 1 0 Mcm10 replication factor Evr1_Alr PF04777.8 KFX89163.1 - 0.23 11.3 1.7 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family ADH_N PF08240.7 KFX89164.1 - 9.4e-30 102.5 0.4 1.7e-29 101.7 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX89164.1 - 2.6e-25 88.4 0.0 4.1e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFX89164.1 - 0.0054 16.3 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 KFX89164.1 - 0.039 13.5 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFX89164.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sen15 PF09631.5 KFX89165.1 - 1.3e-26 92.7 0.0 2.3e-26 91.9 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 KFX89166.1 - 1.2e-38 130.6 1.6 2.2e-38 129.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.10 KFX89167.1 - 5.8e-07 28.8 3.4 1e-06 28.0 2.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KFX89167.1 - 0.0022 17.6 10.7 0.023 14.3 0.1 3.0 2 2 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KFX89167.1 - 0.0029 17.6 23.5 0.0068 16.4 3.1 3.3 2 1 1 3 3 3 3 EamA-like transporter family S-methyl_trans PF02574.11 KFX89167.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase CLU PF13236.1 KFX89170.1 - 4.9e-82 274.6 0.0 7.8e-82 273.9 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KFX89170.1 - 4.7e-49 166.5 0.1 2.7e-48 164.1 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KFX89170.1 - 1.3e-26 92.5 0.7 4.2e-26 90.8 0.5 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KFX89170.1 - 2.1e-20 72.4 11.8 1.3e-10 41.0 1.5 3.7 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFX89170.1 - 5.8e-16 57.8 2.3 1e-05 25.2 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX89170.1 - 0.00075 19.1 2.2 0.4 10.5 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX89170.1 - 0.0034 16.9 11.6 0.15 11.7 0.2 3.6 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 KFX89170.1 - 0.0071 16.1 7.3 0.17 11.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX89170.1 - 0.057 13.0 2.5 5.5 6.7 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF727 PF05303.7 KFX89170.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Ferric_reduct PF01794.14 KFX89172.1 - 2.4e-20 72.8 12.0 5.6e-20 71.6 6.4 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX89172.1 - 1.3e-19 70.6 0.0 4.7e-11 42.8 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX89172.1 - 5.9e-14 51.8 0.0 1.8e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Baculo_11_kDa PF06143.6 KFX89172.1 - 0.0044 16.3 0.1 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF3754 PF12576.3 KFX89172.1 - 0.43 10.2 5.1 1.1 8.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Glyco_hydro_18 PF00704.23 KFX89179.1 - 9.3e-98 327.8 7.0 1.1e-97 327.6 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFX89180.1 - 3.9e-18 65.9 3.0 2.3e-17 63.4 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Cornichon PF03311.9 KFX89182.1 - 0.097 12.8 0.5 0.11 12.6 0.4 1.1 1 0 0 1 1 1 0 Cornichon protein DUF1676 PF07898.8 KFX89183.1 - 0.071 13.4 0.0 0.074 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) A_deaminase PF00962.17 KFX89184.1 - 3.2e-73 246.5 0.0 3.6e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 KFX89186.1 - 1.3e-45 155.7 44.0 1.3e-44 152.3 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89186.1 - 4.8e-07 28.7 14.0 4.8e-07 28.7 9.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Dioxygenase_C PF00775.16 KFX89187.1 - 4.4e-10 39.1 0.0 8.3e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase 2OG-FeII_Oxy PF03171.15 KFX89189.1 - 2.7e-21 75.6 0.0 6.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFX89189.1 - 4.8e-08 33.5 0.0 7.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CMAS PF02353.15 KFX89190.1 - 2e-63 214.0 0.2 2.5e-63 213.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFX89190.1 - 2.1e-11 43.7 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX89190.1 - 1.4e-07 31.9 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX89190.1 - 9.1e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX89190.1 - 0.00012 22.1 0.0 0.0006 19.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89190.1 - 0.00016 22.2 0.0 0.00034 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89190.1 - 0.00019 21.8 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89190.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFX89190.1 - 0.0021 17.4 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KFX89190.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX89190.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KFX89190.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tctex-1 PF03645.8 KFX89192.1 - 1.7e-28 98.3 0.0 2.3e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family SelB-wing_2 PF09106.6 KFX89193.1 - 0.066 13.1 1.4 1.6 8.7 0.1 2.8 2 1 0 2 2 2 0 Elongation factor SelB, winged helix Hydrolase_6 PF13344.1 KFX89198.1 - 1.8e-18 66.2 0.0 2.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GCV_T PF01571.16 KFX89199.1 - 7.8e-34 116.8 0.0 1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.7 KFX89199.1 - 0.059 13.2 0.0 5.7 6.7 0.0 2.4 1 1 0 2 2 2 0 Sarcosine oxidase, gamma subunit family V-ATPase_H_C PF11698.3 KFX89200.1 - 2.8e-40 136.9 0.0 5e-40 136.1 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 KFX89200.1 - 2.3e-22 79.5 0.0 3.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H adh_short PF00106.20 KFX89204.1 - 4.8e-08 33.1 0.0 6.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFX89204.1 - 0.00015 21.8 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KFX89204.1 - 0.00043 20.1 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KFX89204.1 - 0.0012 18.1 0.1 0.0054 16.0 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.15 KFX89204.1 - 0.0042 17.1 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KFX89204.1 - 0.0069 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KFX89204.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFX89204.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPT16 PF08644.6 KFX89205.1 - 0.01 15.6 0.1 0.017 14.9 0.1 1.3 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF2951 PF11166.3 KFX89205.1 - 0.02 14.7 0.7 0.041 13.7 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) TSC22 PF01166.13 KFX89205.1 - 0.031 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family phiKZ_IP PF12699.2 KFX89205.1 - 0.033 13.1 0.1 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins DUF1280 PF06918.9 KFX89205.1 - 0.038 13.1 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) DivIC PF04977.10 KFX89205.1 - 0.089 12.2 0.9 0.2 11.1 0.2 1.8 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L29 PF00831.18 KFX89205.1 - 0.14 11.8 0.5 0.24 11.0 0.3 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein TPR_11 PF13414.1 KFX89207.1 - 9.9e-35 118.0 16.5 2.2e-18 65.6 0.7 3.2 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 KFX89207.1 - 5.2e-25 85.3 13.9 5.5e-05 22.7 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFX89207.1 - 1.7e-21 74.8 15.3 0.00042 19.7 0.3 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFX89207.1 - 4.2e-13 48.0 9.5 0.0021 17.6 0.1 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFX89207.1 - 5.3e-12 45.5 6.0 0.0035 17.2 0.1 4.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX89207.1 - 9.4e-12 45.2 5.2 0.0014 19.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX89207.1 - 7e-10 38.6 2.7 1.2 9.9 0.1 5.3 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX89207.1 - 4.1e-08 33.4 2.1 0.017 15.4 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX89207.1 - 8.8e-08 31.7 3.6 0.0059 16.7 0.1 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX89207.1 - 4.9e-06 25.9 5.9 0.15 11.9 0.1 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFX89207.1 - 0.00029 20.6 2.8 0.019 14.8 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX89207.1 - 0.003 17.3 0.0 0.026 14.3 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFX89207.1 - 0.011 15.7 0.0 0.011 15.7 0.0 3.3 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX89207.1 - 0.017 15.5 2.7 25 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX89207.1 - 0.025 14.7 3.3 0.97 9.6 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 KFX89207.1 - 0.11 11.7 1.4 13 5.1 0.1 3.4 4 0 0 4 4 4 0 SHNi-TPR RR_TM4-6 PF06459.7 KFX89207.1 - 0.27 11.1 5.5 0.14 12.0 2.2 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 HpaP PF09483.5 KFX89207.1 - 1.7 8.5 5.5 3 7.7 3.8 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) RLL PF10036.4 KFX89207.1 - 4.6 6.5 7.1 7.6 5.8 0.4 2.5 3 0 0 3 3 3 0 Putative carnitine deficiency-associated protein adh_short PF00106.20 KFX89209.1 - 9.9e-06 25.5 0.8 1e-05 25.5 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KFX89209.1 - 0.023 14.4 0.3 0.023 14.4 0.2 1.1 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 KFX89209.1 - 0.071 12.7 0.3 0.079 12.6 0.2 1.0 1 0 0 1 1 1 0 KR domain Ank_2 PF12796.2 KFX89217.1 - 1e-30 105.8 4.1 1.5e-15 57.2 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89217.1 - 1.6e-15 56.0 2.0 4.4e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KFX89217.1 - 4.2e-15 55.4 2.5 1.8e-09 37.5 0.3 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX89217.1 - 6.6e-15 53.7 0.6 5.8e-08 32.2 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFX89217.1 - 8.1e-13 48.5 0.6 1.8e-09 37.8 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Crystall PF00030.14 KFX89218.1 - 0.00094 19.0 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.5 KFX89218.1 - 0.002 17.7 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin ParA PF10609.4 KFX89220.1 - 2.8e-35 120.0 0.2 4.7e-35 119.3 0.2 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFX89220.1 - 6.4e-16 58.3 0.0 9.4e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KFX89220.1 - 1.4e-06 27.5 0.0 3.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KFX89220.1 - 4.5e-06 26.6 0.0 3.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KFX89220.1 - 4.6e-05 22.6 1.0 6.7e-05 22.0 0.3 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 KFX89220.1 - 0.0012 17.6 0.3 0.002 16.9 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 KFX89220.1 - 0.0039 16.6 0.1 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KFX89220.1 - 0.0059 15.9 0.3 0.0097 15.2 0.2 1.5 1 1 0 1 1 1 1 YhjQ protein DUF258 PF03193.11 KFX89220.1 - 0.019 14.1 1.0 0.038 13.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 KFX89220.1 - 0.061 12.9 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.1 KFX89220.1 - 0.23 11.0 1.2 11 5.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribonucleas_3_3 PF14622.1 KFX89221.1 - 2.4e-22 79.2 0.0 4.2e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like KAT11 PF08214.6 KFX89222.1 - 7.5e-98 327.8 0.0 8.9e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_hydro_16 PF00722.16 KFX89223.1 - 6.6e-42 142.8 0.6 9e-42 142.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AAA PF00004.24 KFX89225.1 - 6e-38 130.0 0.0 5e-29 101.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 KFX89225.1 - 0.011 15.5 0.1 0.06 13.2 0.0 2.3 2 0 0 2 2 2 0 Bromodomain AAA_2 PF07724.9 KFX89225.1 - 0.08 12.8 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HLH PF00010.21 KFX89226.1 - 1.3e-11 43.9 0.0 4.3e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.17 KFX89234.1 - 1.2e-08 34.4 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX89234.1 - 2.5e-08 33.6 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX89234.1 - 8.3e-06 25.6 0.1 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KFX89234.1 - 0.0024 18.0 0.0 0.0073 16.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 KFX89235.1 - 5.7e-102 341.0 0.0 8.8e-102 340.4 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase Fimbrial_PilY2 PF14481.1 KFX89236.1 - 0.13 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 PBP PF01161.15 KFX89238.1 - 9.3e-11 41.7 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Beta-lactamase PF00144.19 KFX89239.1 - 7.2e-65 219.1 0.0 8.1e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Pyr_redox_3 PF13738.1 KFX89240.1 - 7.1e-17 62.1 0.0 1.6e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX89240.1 - 4.7e-08 31.6 0.0 5.4e-06 24.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX89240.1 - 8.2e-07 28.9 0.2 4.1e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KFX89240.1 - 4.2e-05 23.6 0.0 0.00078 19.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KFX89240.1 - 0.0054 16.6 0.0 0.034 14.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX89240.1 - 0.0055 15.6 0.2 0.86 8.4 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFX89240.1 - 0.0071 15.4 0.2 0.48 9.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KFX89240.1 - 0.0072 16.1 0.1 0.34 10.6 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFX89240.1 - 0.026 13.3 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KFX89240.1 - 0.06 12.2 0.0 5.8 5.7 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3425 PF11905.3 KFX89241.1 - 2e-17 63.3 0.5 4e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Metal_resist PF13801.1 KFX89241.1 - 0.0055 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal resistance Melibiase PF02065.13 KFX89242.1 - 3.5e-18 65.4 3.8 2.9e-16 59.1 0.1 2.3 1 1 0 2 2 2 2 Melibiase Glyco_hydro_62 PF03664.8 KFX89243.1 - 6.1e-151 501.0 13.3 7e-151 500.8 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Glyco_hydro_43 PF04616.9 KFX89244.1 - 2.1e-51 174.7 8.5 3.8e-51 173.8 3.6 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KFX89244.1 - 3.9e-37 127.1 5.2 8.4e-37 126.1 3.6 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 KFX89244.1 - 4.2e-05 23.0 1.9 6.4e-05 22.4 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_10 PF00331.15 KFX89245.1 - 8.5e-101 337.1 0.0 9.7e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KFX89245.1 - 0.013 14.6 0.1 0.061 12.4 0.0 1.8 1 1 1 2 2 2 0 Beta-galactosidase Glyco_hydro_43 PF04616.9 KFX89246.1 - 6.3e-39 133.7 4.2 8.6e-39 133.3 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 WD40 PF00400.27 KFX89247.1 - 3.9e-07 29.6 15.9 0.0019 18.0 0.0 6.2 5 1 0 5 5 5 3 WD domain, G-beta repeat SCAN PF02023.12 KFX89247.1 - 0.04 13.3 0.1 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 SCAN domain Pkinase PF00069.20 KFX89260.1 - 0.045 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain MMPL PF03176.10 KFX89262.1 - 7.6 5.1 7.0 11 4.5 4.8 1.2 1 0 0 1 1 1 0 MMPL family PPTA PF01239.17 KFX89265.1 - 1.3e-42 141.3 8.8 8.7e-08 31.1 1.8 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GHMP_kinases_N PF00288.21 KFX89266.1 - 2.1e-19 69.3 0.1 6.3e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFX89266.1 - 1.3e-08 34.8 0.1 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KFX89266.1 - 0.0084 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Peptidase_M48 PF01435.13 KFX89268.1 - 1.8e-49 168.3 0.0 3.1e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KFX89268.1 - 0.00043 19.3 0.1 0.00082 18.4 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 KFX89268.1 - 0.017 14.3 0.9 0.027 13.6 0.2 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF955 PF06114.8 KFX89268.1 - 0.14 11.9 0.2 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Lipase_3 PF01764.20 KFX89269.1 - 3.2e-38 130.5 0.0 6.8e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KFX89269.1 - 6.8e-07 29.0 0.4 1.7e-06 27.7 0.3 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 KFX89269.1 - 5.7e-05 22.5 0.6 0.00024 20.5 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KFX89269.1 - 0.00018 21.2 0.1 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KFX89269.1 - 0.00028 20.4 0.3 0.00084 18.8 0.2 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 KFX89269.1 - 0.00038 20.4 0.1 0.00054 19.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KFX89269.1 - 0.0011 18.6 0.4 0.0028 17.4 0.3 1.9 1 1 0 1 1 1 1 Cutinase PGAP1 PF07819.8 KFX89269.1 - 0.0025 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFX89269.1 - 0.007 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 KFX89269.1 - 0.054 13.0 0.4 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 KFX89269.1 - 0.06 13.5 0.1 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain MitMem_reg PF13012.1 KFX89270.1 - 8.7e-39 132.1 0.2 2.4e-38 130.7 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Cyclin PF08613.6 KFX89270.1 - 4.3e-28 98.6 0.0 1e-27 97.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin JAB PF01398.16 KFX89270.1 - 5.4e-27 93.8 0.0 1.4e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cyclin_N PF00134.18 KFX89270.1 - 0.00032 20.2 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4407 PF14362.1 KFX89270.1 - 0.12 11.2 1.6 0.22 10.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 KFX89270.1 - 0.55 8.1 5.0 0.83 7.6 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein ADK PF00406.17 KFX89271.1 - 1.3e-58 197.1 0.1 1.7e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFX89271.1 - 2.2e-14 52.8 0.0 5.9e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFX89271.1 - 0.00041 21.1 0.0 0.00064 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX89271.1 - 0.00082 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX89271.1 - 0.0028 17.9 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX89271.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 KFX89271.1 - 0.076 12.1 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Coprogen_oxidas PF01218.13 KFX89272.1 - 2.6e-135 449.7 0.2 3.1e-135 449.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 KFX89273.1 - 5.3e-51 170.9 0.2 6.2e-51 170.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFX89273.1 - 3.6e-06 27.0 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2665 PF11654.3 KFX89274.1 - 4e-06 26.2 0.1 7.9e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) Mito_carr PF00153.22 KFX89275.1 - 2.9e-28 97.4 1.1 5.3e-14 51.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc82 PF05645.8 KFX89276.1 - 3.4e-49 167.6 0.2 4.3e-46 157.5 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KFX89276.1 - 3.6e-18 65.1 2.4 1.6e-15 56.7 0.2 3.6 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KFX89276.1 - 2.3e-11 43.1 0.6 1.5e-06 27.6 0.1 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 KFX89276.1 - 0.00063 19.3 0.0 4.3 7.1 0.0 3.7 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB Peptidase_M16 PF00675.15 KFX89277.1 - 5.1e-17 62.0 0.1 9.1e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFX89277.1 - 4.4e-15 55.8 0.0 8.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain JAB PF01398.16 KFX89281.1 - 5.2e-15 55.1 0.0 8.8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KFX89281.1 - 2e-08 34.1 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KFX89281.1 - 4.2e-06 26.2 0.2 1.3e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Vma12 PF11712.3 KFX89283.1 - 7.3e-38 129.4 0.0 1.4e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase polyprenyl_synt PF00348.12 KFX89284.1 - 2.2e-54 184.0 0.0 9.9e-52 175.3 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KFX89284.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Milton PF12448.3 KFX89284.1 - 0.33 11.1 7.9 3.8 7.6 0.4 2.3 2 0 0 2 2 2 0 Kinesin associated protein DNA_topoisoIV PF00521.15 KFX89287.1 - 1.2e-121 406.5 0.1 5.6e-121 404.3 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KFX89287.1 - 2.9e-33 114.5 4.3 7e-33 113.2 3.0 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KFX89287.1 - 4.3e-12 45.8 0.0 1.5e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KFX89287.1 - 1.2e-09 37.8 0.0 4.5e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GATA PF00320.22 KFX89288.1 - 1.8e-06 27.1 15.2 0.0027 17.0 0.2 4.1 3 0 0 3 3 3 3 GATA zinc finger Cupin_4 PF08007.7 KFX89288.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Ist1 PF03398.9 KFX89289.1 - 4.9e-63 211.4 2.5 6.4e-63 211.0 1.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2422 PF10337.4 KFX89290.1 - 5.4e-31 107.8 0.6 5.9e-19 68.1 0.0 4.4 3 2 2 5 5 5 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KFX89290.1 - 4.4e-10 39.5 19.2 4.4e-10 39.5 13.3 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KFX89290.1 - 6.6e-07 28.3 7.4 6.6e-07 28.3 5.1 2.9 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 KFX89290.1 - 4.4e-06 25.4 9.5 4.4e-06 25.4 6.6 3.2 4 1 0 4 4 4 1 Fusaric acid resistance protein family DUF2421 PF10334.4 KFX89290.1 - 0.00042 20.0 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) GFA PF04828.9 KFX89292.1 - 1.5e-14 53.7 10.6 2.6e-12 46.5 0.2 3.4 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KFX89292.1 - 0.058 13.2 4.0 3.7 7.4 0.1 2.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Lar_restr_allev PF14354.1 KFX89292.1 - 0.23 11.7 7.5 5.2 7.4 0.2 3.9 5 0 0 5 5 5 0 Restriction alleviation protein Lar Clat_adaptor_s PF01217.15 KFX89293.1 - 2.4e-56 189.4 1.2 2.8e-56 189.1 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.2 KFX89294.1 - 7e-54 179.6 0.0 1.7e-34 117.5 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KFX89294.1 - 3.5e-14 52.8 0.1 1.6e-12 47.4 0.0 2.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KFX89294.1 - 2.9e-13 49.4 0.1 0.00011 22.0 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KFX89294.1 - 1.9e-10 40.7 0.0 0.00032 20.7 0.0 3.8 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KFX89294.1 - 1.1e-05 25.1 0.0 2.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 KFX89294.1 - 0.0069 16.1 0.7 0.97 9.2 0.1 3.2 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 KFX89294.1 - 0.18 11.1 0.1 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 KFX89294.1 - 0.26 10.5 0.2 0.43 9.8 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Septin PF00735.13 KFX89295.1 - 7.2e-122 405.8 0.0 7.2e-122 405.8 0.0 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFX89295.1 - 7.4e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KFX89295.1 - 5.8e-05 23.4 1.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KFX89295.1 - 0.0001 21.5 0.7 0.0011 18.2 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFX89295.1 - 0.00015 21.2 0.4 0.0068 15.8 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFX89295.1 - 0.00098 18.6 2.2 0.0025 17.3 1.4 2.0 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 KFX89295.1 - 0.0015 17.6 1.3 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FtsK_SpoIIIE PF01580.13 KFX89295.1 - 0.0015 18.0 0.1 0.022 14.2 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KFX89295.1 - 0.0017 18.4 0.0 0.012 15.6 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 KFX89295.1 - 0.0023 18.4 0.0 0.0087 16.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KFX89295.1 - 0.006 16.7 0.3 0.03 14.4 0.0 2.4 2 2 1 3 3 3 1 AAA domain Ras PF00071.17 KFX89295.1 - 0.0071 15.7 1.2 0.03 13.6 0.0 2.5 3 1 0 3 3 3 1 Ras family AAA_29 PF13555.1 KFX89295.1 - 0.0089 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KFX89295.1 - 0.02 14.4 0.1 4.3 6.8 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KFX89295.1 - 0.032 14.0 6.9 0.46 10.2 0.0 3.4 3 1 0 3 3 2 0 Dynamin family MobB PF03205.9 KFX89295.1 - 0.054 13.2 0.2 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFX89295.1 - 0.061 13.4 0.4 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KFX89295.1 - 0.08 12.5 0.5 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 KFX89295.1 - 0.14 12.2 10.6 0.26 11.3 7.3 1.4 1 0 0 1 1 1 0 YlqD protein Strep_SA_rep PF06696.6 KFX89295.1 - 0.25 11.1 3.3 0.34 10.7 1.1 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Exonuc_VII_L PF02601.10 KFX89295.1 - 0.26 10.4 8.1 0.47 9.6 5.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KFX89295.1 - 0.8 9.2 9.9 1.3 8.6 6.8 1.3 1 0 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 KFX89295.1 - 1.2 8.3 6.5 1.8 7.7 4.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 KFX89295.1 - 2.3 7.9 7.4 2.9 7.6 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 KFX89295.1 - 7.1 4.3 10.4 12 3.6 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 KFX89297.1 - 2.6e-33 115.2 33.2 2.6e-33 115.2 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL PF00657.17 KFX89298.1 - 1.7e-14 54.1 0.3 2.9e-14 53.4 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_C13 PF01650.13 KFX89300.1 - 5.1e-41 140.6 0.0 6.5e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_1 PF00300.17 KFX89301.1 - 6.6e-09 36.0 0.1 9.8e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Pyr_redox_3 PF13738.1 KFX89302.1 - 2e-20 73.7 0.1 6.7e-19 68.7 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX89302.1 - 1.1e-14 53.5 0.0 5.6e-14 51.2 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX89302.1 - 7.5e-13 48.8 0.0 2.3e-08 34.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX89302.1 - 1e-11 44.3 0.0 6.4e-09 35.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX89302.1 - 2.5e-08 33.8 0.5 4.7e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX89302.1 - 9.1e-08 31.3 0.2 2.2e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX89302.1 - 1.8e-06 28.2 3.7 0.0033 17.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX89302.1 - 3.6e-05 23.5 3.7 0.0028 17.4 0.4 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KFX89302.1 - 0.0042 16.7 0.2 0.0075 15.9 0.1 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFX89302.1 - 0.0065 14.9 1.0 0.36 9.2 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.15 KFX89302.1 - 0.0099 15.9 0.3 0.53 10.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFX89302.1 - 0.039 14.2 0.1 0.62 10.3 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KFX89302.1 - 0.043 13.3 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFX89302.1 - 0.061 12.1 0.2 0.061 12.1 0.2 1.8 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KFX89302.1 - 0.16 11.0 0.1 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KFX89302.1 - 0.21 10.4 0.5 0.98 8.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_7 PF00840.15 KFX89304.1 - 1e-195 650.2 18.6 1.2e-195 650.0 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pam17 PF08566.5 KFX89304.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 P12 PF12669.2 KFX89305.1 - 0.017 15.3 3.4 0.017 15.3 2.3 2.5 2 1 0 2 2 2 0 Virus attachment protein p12 family Collagen PF01391.13 KFX89305.1 - 0.85 9.2 4.1 0.21 11.1 0.5 1.7 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Zip PF02535.17 KFX89305.1 - 1.8 7.5 8.9 3 6.7 6.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPR_3 PF13812.1 KFX89306.1 - 6.1e-21 72.8 7.4 0.0047 17.0 0.0 8.9 9 0 0 9 9 9 6 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFX89306.1 - 2.6e-16 59.2 0.4 0.11 12.4 0.0 8.5 6 3 3 9 9 9 4 PPR repeat family LSM PF01423.17 KFX89306.1 - 8e-15 54.1 0.0 3.3e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 LSM domain PPR PF01535.15 KFX89306.1 - 1.6e-07 30.8 13.2 3.9 7.6 0.2 7.2 8 0 0 8 8 8 4 PPR repeat SM-ATX PF14438.1 KFX89306.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain TPR_11 PF13414.1 KFX89307.1 - 1.3e-09 37.5 3.3 2.9e-05 23.6 0.7 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFX89307.1 - 4.5e-08 32.3 0.5 0.22 11.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFX89307.1 - 4.2e-07 29.3 0.2 0.3 11.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX89307.1 - 0.019 15.6 3.5 0.036 14.7 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFX89307.1 - 0.09 13.0 0.0 0.74 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Surp PF01805.15 KFX89311.1 - 7.3e-17 60.7 0.1 1.5e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Surp module AAA_11 PF13086.1 KFX89317.1 - 3.3e-60 203.6 0.1 4.7e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KFX89317.1 - 5.3e-56 189.1 0.0 8.6e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX89317.1 - 3.9e-13 48.9 0.0 2.6e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFX89317.1 - 2.9e-10 40.0 0.0 1.2e-08 34.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFX89317.1 - 2.7e-07 30.5 0.0 1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFX89317.1 - 9.6e-06 24.7 0.2 0.00016 20.8 0.2 2.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KFX89317.1 - 4.2e-05 23.1 0.0 0.24 10.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KFX89317.1 - 0.0001 21.7 0.5 0.0015 17.9 0.0 2.5 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KFX89317.1 - 0.0006 19.9 0.1 0.0069 16.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFX89317.1 - 0.0034 16.7 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 KFX89317.1 - 0.0037 16.9 0.0 0.12 11.9 0.0 2.3 1 1 0 1 1 1 1 Helicase FtsK_SpoIIIE PF01580.13 KFX89317.1 - 0.0041 16.6 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 KFX89317.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KFX89317.1 - 0.0046 16.9 0.1 0.011 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 KFX89317.1 - 0.0046 16.2 0.0 0.091 11.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.1 KFX89317.1 - 0.0052 16.2 0.0 8.3 5.7 0.0 3.2 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.12 KFX89317.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 KFX89317.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KFX89317.1 - 0.017 15.3 1.0 0.076 13.2 0.0 2.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 KFX89317.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain 4HB_MCP_1 PF12729.2 KFX89317.1 - 0.086 12.1 0.2 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Mg_chelatase PF01078.16 KFX89317.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.9 KFX89317.1 - 0.092 11.6 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ABC_tran PF00005.22 KFX89317.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KFX89317.1 - 0.16 12.8 0.7 0.66 10.8 0.2 2.2 1 1 0 2 2 1 0 AAA domain E1-E2_ATPase PF00122.15 KFX89320.1 - 4.5e-63 212.3 7.0 8.8e-63 211.4 4.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFX89320.1 - 2.9e-30 106.2 0.0 8.5e-29 101.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX89320.1 - 1.7e-18 65.7 0.0 5.1e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 KFX89320.1 - 7.7e-17 61.4 0.0 7.7e-17 61.4 0.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.2 KFX89320.1 - 9.4e-14 52.0 0.1 2.8e-13 50.4 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX89320.1 - 2.5e-13 49.7 0.0 5.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX89320.1 - 1.8e-05 24.4 3.0 6e-05 22.7 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 2TM PF13239.1 KFX89320.1 - 0.061 13.3 1.2 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 2TM domain DUF2510 PF10708.4 KFX89320.1 - 0.086 12.3 0.1 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) EMP70 PF02990.11 KFX89320.1 - 0.13 10.6 0.1 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 bZIP_1 PF00170.16 KFX89324.1 - 0.00076 19.3 11.1 0.0031 17.4 6.2 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFX89324.1 - 0.015 15.1 9.3 0.092 12.5 1.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper SART-1 PF03343.8 KFX89324.1 - 0.12 10.6 7.2 0.16 10.2 5.0 1.1 1 0 0 1 1 1 0 SART-1 family DNA_ligase_A_M PF01068.16 KFX89329.1 - 4.1e-57 192.8 0.2 2.2e-45 154.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFX89329.1 - 9.6e-52 175.3 0.0 1.9e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFX89329.1 - 4.7e-28 97.4 0.0 3.2e-27 94.7 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region tRNA-synt_2 PF00152.15 KFX89330.1 - 6.7e-72 242.0 0.0 1.1e-71 241.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFX89330.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lipoprotein_16 PF03923.8 KFX89330.1 - 0.014 14.7 0.1 0.14 11.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized lipoprotein tRNA_anti_2 PF13742.1 KFX89330.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain IQ PF00612.22 KFX89332.1 - 0.0008 18.8 3.2 0.0022 17.4 2.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif RGS-like PF09128.6 KFX89332.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain PH PF00169.24 KFX89337.1 - 2.5e-22 79.0 0.6 5.6e-13 48.9 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 KFX89337.1 - 5.2e-09 36.3 2.7 3.2e-05 24.1 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 KFX89337.1 - 2.5e-08 34.1 0.3 0.0024 17.9 0.1 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KFX89337.1 - 9.7e-06 25.5 0.1 1.9e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFX89337.1 - 0.00013 21.8 0.3 0.00035 20.4 0.1 1.7 2 0 0 2 2 2 1 PH domain DNA_pol_B PF00136.16 KFX89340.1 - 7.4e-109 364.5 3.1 1e-108 364.1 2.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KFX89340.1 - 9.1e-52 175.1 0.9 1.6e-51 174.3 0.6 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger UAA PF08449.6 KFX89340.1 - 3.1e-43 147.8 0.6 4.7e-43 147.2 0.4 1.2 1 0 0 1 1 1 1 UAA transporter family DNA_pol_B_exo1 PF03104.14 KFX89340.1 - 5e-40 137.3 0.0 1.2e-39 136.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KFX89340.1 - 6.8e-23 80.2 10.4 6.8e-23 80.2 7.2 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Nuc_sug_transp PF04142.10 KFX89340.1 - 0.00038 19.6 0.2 0.00065 18.8 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PPR_2 PF13041.1 KFX89341.1 - 2.5e-25 88.2 2.2 4.4e-17 61.7 0.0 4.5 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 KFX89341.1 - 7.3e-09 35.0 1.8 0.00049 19.8 0.0 5.4 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 KFX89341.1 - 6.3e-08 32.3 1.2 0.86 10.0 0.0 6.5 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFX89341.1 - 1.2e-05 24.6 1.2 0.016 14.6 0.0 4.6 5 0 0 5 5 5 1 PPR repeat YodL PF14191.1 KFX89341.1 - 0.024 15.1 0.4 3 8.3 0.0 3.2 3 0 0 3 3 3 0 YodL-like RRM_1 PF00076.17 KFX89343.1 - 0.0012 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LON PF02190.11 KFX89344.1 - 3.3e-18 66.1 0.0 4.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain DUF4210 PF13915.1 KFX89351.1 - 1.5e-24 86.0 0.0 3.1e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 KFX89351.1 - 1e-21 76.5 2.1 1.8e-21 75.7 0.4 2.2 2 0 0 2 2 2 1 Chromosome segregation during meiosis Mis12 PF05859.7 KFX89354.1 - 3.5e-34 117.6 0.0 6.3e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein PPR_2 PF13041.1 KFX89355.1 - 5.2e-27 93.5 0.0 2.2e-07 30.7 0.0 9.0 8 1 1 9 9 9 5 PPR repeat family PPR_3 PF13812.1 KFX89355.1 - 1.2e-15 56.3 2.9 0.0014 18.7 0.0 9.5 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR PF01535.15 KFX89355.1 - 1.1e-14 53.2 0.4 0.005 16.7 0.1 7.1 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 KFX89355.1 - 1.1e-13 50.4 0.3 0.017 14.6 0.0 8.3 9 0 0 9 9 9 3 PPR repeat ECSIT PF06239.6 KFX89355.1 - 0.0048 15.8 0.6 9.4 5.0 0.0 3.5 2 1 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.6 KFX89355.1 - 0.15 12.2 0.4 0.66 10.1 0.3 2.2 1 1 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Vps39_2 PF10367.4 KFX89355.1 - 0.2 11.8 0.3 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 His_Phos_2 PF00328.17 KFX89356.1 - 2.4e-23 83.0 0.0 5.9e-21 75.1 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-CCHC_5 PF14787.1 KFX89356.1 - 0.13 11.7 0.1 0.32 10.4 0.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger His_Phos_1 PF00300.17 KFX89357.1 - 7.6e-21 74.8 0.0 9.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cupin_2 PF07883.6 KFX89358.1 - 2.2e-06 27.0 0.0 6.1e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KFX89358.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Methyltransf_11 PF08241.7 KFX89359.1 - 2e-13 50.6 0.0 4.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89359.1 - 1.1e-10 41.3 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89359.1 - 4.8e-10 39.8 0.0 8.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX89359.1 - 1.7e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89359.1 - 6.2e-08 33.2 0.0 1.6e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX89359.1 - 3.3e-07 30.1 0.0 6.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX89359.1 - 0.00047 19.3 0.0 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KFX89359.1 - 0.00059 19.3 0.0 0.00096 18.6 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 KFX89359.1 - 0.0013 17.9 0.0 0.0028 16.8 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.1 KFX89359.1 - 0.0097 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX89359.1 - 0.11 11.8 0.0 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain CHAP PF05257.11 KFX89362.1 - 0.0028 17.2 0.2 0.0074 15.9 0.0 1.8 2 0 0 2 2 2 1 CHAP domain Adeno_E3_14_5 PF04834.7 KFX89362.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.4 4 2 0 4 4 4 0 Early E3 14.5 kDa protein Pkinase PF00069.20 KFX89364.1 - 2.4e-23 82.5 0.0 5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KFX89364.1 - 9.6e-16 56.9 0.4 1.2e-07 31.3 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 KFX89364.1 - 2.1e-11 42.9 5.6 0.0095 15.9 0.0 6.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KFX89364.1 - 9.8e-08 32.1 5.0 0.066 13.5 0.2 3.9 3 1 0 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 KFX89364.1 - 6.4e-06 26.4 1.8 0.012 16.0 0.7 4.3 5 0 0 5 5 5 1 HEAT-like repeat Pkinase_Tyr PF07714.12 KFX89364.1 - 2.5e-05 23.4 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2435 PF10363.4 KFX89364.1 - 0.0046 16.8 0.1 3 7.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KFX89364.1 - 0.052 13.3 0.2 1.3 8.8 0.1 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 KFX89364.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AMP-binding PF00501.23 KFX89365.1 - 3.7e-28 98.0 0.0 1.2e-27 96.4 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme LRR_9 PF14580.1 KFX89367.1 - 2.1e-50 170.7 0.1 3.8e-50 169.8 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 KFX89367.1 - 3.8e-11 42.3 1.9 3.7e-06 26.4 0.1 3.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX89367.1 - 1.4e-10 40.7 0.4 2.8e-08 33.4 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KFX89367.1 - 0.0057 16.6 1.6 17 6.2 0.1 4.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 KFX89367.1 - 0.013 15.4 0.2 27 5.2 0.1 4.2 4 1 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 KFX89367.1 - 0.03 14.3 1.5 21 5.6 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4349 PF14257.1 KFX89367.1 - 0.12 11.6 1.1 0.19 10.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pox_A_type_inc PF04508.7 KFX89367.1 - 6.7 6.7 6.3 6.7 6.7 0.3 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ATP-synt_C PF00137.16 KFX89368.1 - 5.7e-29 99.8 24.9 2.8e-18 65.5 4.2 2.5 3 0 0 3 3 3 2 ATP synthase subunit C DUF3120 PF11318.3 KFX89368.1 - 0.053 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Oxidored_q2 PF00420.19 KFX89368.1 - 2.5 7.7 7.6 2.6 7.7 2.1 3.0 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cation_efflux PF01545.16 KFX89368.1 - 8.8 5.2 12.3 0.12 11.4 1.7 2.5 1 1 1 2 2 2 0 Cation efflux family TFIIA_gamma_C PF02751.9 KFX89369.1 - 1.3e-25 88.9 2.4 1.7e-25 88.5 1.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KFX89369.1 - 9.4e-25 85.9 0.0 1.3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Methyltransf_11 PF08241.7 KFX89371.1 - 6.4e-08 32.9 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX89371.1 - 1.9e-06 27.7 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89371.1 - 0.0002 21.7 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89371.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX89371.1 - 0.045 12.8 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HeLo PF14479.1 KFX89373.1 - 1.7e-06 27.9 0.2 4.9e-06 26.4 0.2 1.8 1 0 0 1 1 1 1 Prion-inhibition and propagation FliG_C PF01706.11 KFX89374.1 - 0.19 11.7 3.1 0.38 10.7 0.3 2.5 2 0 0 2 2 2 0 FliG C-terminal domain RmuC PF02646.11 KFX89374.1 - 0.55 9.0 6.9 0.026 13.3 0.5 1.9 2 1 1 3 3 3 0 RmuC family Lipase_GDSL_2 PF13472.1 KFX89375.1 - 3.8e-11 43.4 0.3 1.2e-09 38.5 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX89375.1 - 6.1e-05 22.9 6.6 0.00025 20.9 3.3 3.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_18 PF00704.23 KFX89376.1 - 8.9e-75 252.2 0.0 1.4e-74 251.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX89376.1 - 1e-07 31.7 8.2 1e-07 31.7 5.7 3.2 2 1 0 2 2 2 1 Chitin recognition protein Glyco_hydro_85 PF03644.8 KFX89376.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Reprolysin_3 PF13582.1 KFX89377.1 - 0.0029 18.1 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFX89377.1 - 0.01 15.5 0.1 0.055 13.2 0.0 2.1 2 0 0 2 2 2 0 Matrixin Reprolysin_2 PF13574.1 KFX89377.1 - 0.019 15.0 0.9 0.031 14.3 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 KFX89377.1 - 0.021 14.2 1.1 0.084 12.2 0.1 2.2 3 0 0 3 3 3 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.1 KFX89377.1 - 0.051 13.4 0.1 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFX89377.1 - 0.055 12.9 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like LysM PF01476.15 KFX89378.1 - 1.4e-16 60.0 1.3 0.004 16.9 0.0 4.4 4 0 0 4 4 4 4 LysM domain ABC2_membrane PF01061.19 KFX89380.1 - 4.3e-83 277.6 57.8 1.5e-46 158.2 16.0 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KFX89380.1 - 2.5e-36 124.9 0.0 5.4e-17 62.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFX89380.1 - 1.4e-35 121.0 9.7 1.2e-31 108.4 0.1 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KFX89380.1 - 3.2e-18 65.5 0.1 7.3e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFX89380.1 - 4.4e-07 29.5 0.0 0.00034 20.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFX89380.1 - 3.1e-05 23.3 0.0 0.11 11.6 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFX89380.1 - 4.2e-05 22.7 0.3 0.00074 18.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX89380.1 - 7.1e-05 22.9 0.0 0.099 12.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 KFX89380.1 - 7.3e-05 22.2 0.7 0.0092 15.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFX89380.1 - 0.00011 22.1 0.1 0.085 12.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.2 KFX89380.1 - 0.00025 20.2 39.4 0.021 13.8 8.4 3.3 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KFX89380.1 - 0.00065 19.1 1.4 0.0086 15.5 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX89380.1 - 0.00075 19.5 0.9 0.017 15.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KFX89380.1 - 0.0041 16.0 0.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.1 KFX89380.1 - 0.0044 17.0 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KFX89380.1 - 0.0081 15.7 0.9 1.2 8.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KFX89380.1 - 0.012 16.0 0.0 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 KFX89380.1 - 0.013 15.2 1.7 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KFX89380.1 - 0.015 14.9 2.0 1.6 8.4 0.3 2.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KFX89380.1 - 0.016 15.4 0.1 0.85 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX89380.1 - 0.027 15.2 0.0 1.9 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KFX89380.1 - 0.029 14.5 0.0 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFX89380.1 - 0.036 14.0 0.1 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFX89380.1 - 0.071 12.5 0.3 12 5.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFX89380.1 - 0.091 12.3 2.6 5.6 6.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 KFX89380.1 - 0.12 12.0 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KFX89380.1 - 0.13 12.5 0.5 0.28 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain Septin PF00735.13 KFX89380.1 - 0.34 9.8 0.1 2.8 6.8 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 KFX89380.1 - 1.1 8.2 0.0 2.5 7.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF1129 PF06570.6 KFX89380.1 - 1.2 8.4 6.4 5.2 6.3 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Transferase PF02458.10 KFX89381.1 - 2.1e-16 59.4 0.0 1.6e-09 36.7 0.0 2.9 2 1 0 2 2 2 2 Transferase family Chalcone PF02431.10 KFX89381.1 - 0.16 11.3 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 Chalcone-flavanone isomerase Transferase PF02458.10 KFX89382.1 - 2e-23 82.5 0.0 8e-22 77.2 0.0 1.9 2 0 0 2 2 2 2 Transferase family HlyD_2 PF12700.2 KFX89385.1 - 0.44 9.6 1.9 0.71 8.9 1.4 1.3 1 1 0 1 1 1 0 HlyD family secretion protein DUF1510 PF07423.6 KFX89399.1 - 0.025 13.9 13.1 0.029 13.7 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KFX89399.1 - 0.087 10.5 8.2 0.098 10.3 5.7 1.1 1 0 0 1 1 1 0 Ycf1 Med19 PF10278.4 KFX89399.1 - 0.12 11.9 19.7 0.17 11.5 13.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_pol_3_Rpc31 PF11705.3 KFX89399.1 - 0.23 11.3 13.1 0.31 10.9 9.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Neur_chan_memb PF02932.11 KFX89399.1 - 0.45 10.3 4.5 0.53 10.1 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hex_IIIa PF02455.11 KFX89399.1 - 0.9 8.1 5.8 1 8.0 4.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SAPS PF04499.10 KFX89399.1 - 0.91 8.0 5.2 0.97 7.9 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.1 KFX89399.1 - 1 8.2 8.6 1.2 8.0 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.2 KFX89399.1 - 1.3 6.5 4.6 1.3 6.6 3.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 KFX89399.1 - 1.6 6.7 13.2 1.8 6.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4557 PF15101.1 KFX89399.1 - 1.6 8.5 6.5 1.9 8.2 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MIP-T3 PF10243.4 KFX89399.1 - 1.7 7.0 30.1 2 6.7 20.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NARP1 PF12569.3 KFX89399.1 - 2.2 6.9 19.6 2.6 6.6 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 KFX89399.1 - 3.5 7.4 17.2 4.3 7.1 11.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF853 PF05872.7 KFX89399.1 - 6.1 5.0 5.7 7.2 4.8 3.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cas_Csy4 PF09618.5 KFX89399.1 - 9.2 6.0 8.0 12 5.6 5.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Cofilin_ADF PF00241.15 KFX89400.1 - 4e-11 42.8 0.0 5.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 KFX89401.1 - 2.2e-27 95.2 0.1 3e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain LETM1 PF07766.8 KFX89404.1 - 7.9e-12 44.7 3.2 1.4e-10 40.7 0.2 2.1 1 1 0 2 2 2 2 LETM1-like protein RRM_1 PF00076.17 KFX89405.1 - 1.7e-10 40.3 0.0 3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX89405.1 - 4e-07 29.9 0.0 7.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX89405.1 - 0.097 12.5 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 KFX89406.1 - 4.3e-12 45.8 1.0 7.4e-12 45.0 0.7 1.4 1 0 0 1 1 1 1 RF-1 domain RNase_H2_suC PF08615.6 KFX89408.1 - 0.053 13.3 1.5 0.19 11.5 1.0 2.2 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Glyco_hydro_35 PF01301.14 KFX89409.1 - 6.9e-85 285.1 0.0 1.2e-84 284.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KFX89409.1 - 4.4e-64 215.1 1.6 4.4e-64 215.1 1.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 IF-2B PF01008.12 KFX89409.1 - 2.9e-59 200.3 10.7 4.6e-35 120.9 0.0 3.1 3 1 0 3 3 3 2 Initiation factor 2 subunit family BetaGal_dom4_5 PF13364.1 KFX89409.1 - 8.1e-48 161.2 11.5 8.8e-26 90.3 3.5 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KFX89409.1 - 4.5e-23 80.4 0.1 9.7e-23 79.3 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF4646 PF15496.1 KFX89409.1 - 0.00057 19.9 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Allexi_40kDa PF05549.6 KFX89409.1 - 0.44 9.7 2.0 0.43 9.8 0.1 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein PEHE PF15275.1 KFX89409.1 - 0.48 10.8 7.0 0.28 11.6 0.4 3.1 3 0 0 3 3 3 0 PEHE domain AcetylCoA_hydro PF02550.10 KFX89410.1 - 2.3e-48 164.6 0.0 3.7e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KFX89410.1 - 1.4e-38 131.9 0.0 2.5e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_88 PF07470.8 KFX89410.1 - 1.3e-15 57.2 0.0 2.6e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CorA PF01544.13 KFX89410.1 - 3.2e-05 23.0 0.4 0.00013 21.1 0.3 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Asp PF00026.18 KFX89411.1 - 4.9e-11 42.4 0.7 8.2e-11 41.6 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4448 PF14610.1 KFX89411.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KFX89411.1 - 0.021 13.0 0.0 0.039 12.2 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF912 PF06024.7 KFX89411.1 - 0.03 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 KFX89411.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 KFX89411.1 - 0.2 12.0 1.1 0.4 11.1 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3377 PF11857.3 KFX89411.1 - 0.7 9.5 2.8 3.8 7.1 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Pkinase PF00069.20 KFX89413.1 - 7.1e-69 231.8 0.0 1.2e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89413.1 - 4.4e-49 166.9 0.0 6.5e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX89413.1 - 0.00054 19.0 0.0 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.7 KFX89414.1 - 1.2e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain AAA_17 PF13207.1 KFX89415.1 - 3.8e-07 30.9 0.0 1.5e-06 29.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFX89415.1 - 1.9e-06 27.5 0.0 2.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 KFX89415.1 - 4.2e-06 27.0 0.0 1.9e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX89415.1 - 0.00021 20.4 0.3 0.022 13.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KFX89415.1 - 0.00021 21.3 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KFX89415.1 - 0.00023 20.1 0.0 0.00041 19.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 KFX89415.1 - 0.00091 19.1 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX89415.1 - 0.0011 18.6 0.4 0.0038 16.9 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KFX89415.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFX89415.1 - 0.0019 17.6 0.0 0.12 11.7 0.0 2.5 3 0 0 3 3 3 1 Thymidylate kinase T2SE PF00437.15 KFX89415.1 - 0.0094 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 KFX89415.1 - 0.0099 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.22 KFX89415.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 KFX89415.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFX89415.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KFX89415.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.5 KFX89415.1 - 0.024 13.8 0.1 0.048 12.8 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.14 KFX89415.1 - 0.027 13.9 0.3 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KFX89415.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KFX89415.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 KFX89415.1 - 0.041 13.5 0.0 0.097 12.3 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 KFX89415.1 - 0.047 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KFX89415.1 - 0.051 13.9 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX89415.1 - 0.057 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFX89415.1 - 0.058 12.4 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KFX89415.1 - 0.07 12.6 0.0 0.084 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFX89415.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_10 PF12846.2 KFX89415.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 KFX89415.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KFX89415.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2997 PF11211.3 KFX89418.1 - 0.014 14.7 1.8 3.8 6.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) TPR_MLP1_2 PF07926.7 KFX89418.1 - 2.5 7.8 24.5 0.19 11.5 12.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein PRTP PF01366.13 KFX89418.1 - 3.7 5.4 10.5 4.9 5.0 7.3 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF4351 PF14261.1 KFX89418.1 - 3.7 7.4 6.6 4.8 7.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) SlyX PF04102.7 KFX89418.1 - 7.3 7.0 12.7 0.3 11.4 1.9 2.9 2 1 1 3 3 3 0 SlyX Fungal_trans PF04082.13 KFX89419.1 - 2.4e-12 46.3 0.5 4.3e-12 45.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89419.1 - 3e-06 27.0 11.7 5.4e-06 26.2 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 KFX89420.1 - 1.5e-47 162.1 0.4 1.9e-47 161.8 0.3 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Amidohydro_4 PF13147.1 KFX89422.1 - 1.7e-26 93.8 0.2 4.5e-15 56.4 0.1 2.3 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KFX89422.1 - 1.1e-13 51.6 0.4 6.9e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KFX89422.1 - 1.4e-12 47.5 2.1 3.4e-10 39.7 0.1 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFX89422.1 - 2.5e-08 33.5 0.1 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase FMO-like PF00743.14 KFX89423.1 - 6.8e-15 54.2 0.0 1.7e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX89423.1 - 7.4e-13 49.0 0.0 1.4e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX89423.1 - 3.4e-06 26.9 0.0 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX89423.1 - 0.00014 21.6 0.0 0.00033 20.4 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFX89423.1 - 0.00017 21.5 0.0 0.00041 20.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX89423.1 - 0.0036 15.8 0.1 0.0074 14.7 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KFX89423.1 - 0.064 12.3 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KFX89423.1 - 0.1 13.0 0.0 24 5.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX89423.1 - 0.13 11.1 0.0 0.3 9.9 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3782 PF12644.2 KFX89423.1 - 0.16 11.7 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF1996 PF09362.5 KFX89425.1 - 6.4e-47 160.1 1.4 2.7e-26 92.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) MFS_1 PF07690.11 KFX89426.1 - 3.1e-27 95.2 20.8 4e-27 94.8 14.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX89426.1 - 0.21 11.3 7.7 0.57 10.0 1.4 2.7 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 KFX89427.1 - 2.8e-46 157.8 40.8 1.2e-35 122.8 11.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89427.1 - 1.1e-15 57.2 22.2 5.4e-13 48.3 7.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Arylsulfotran_2 PF14269.1 KFX89428.1 - 2.6e-75 253.3 2.4 3.5e-75 252.9 1.6 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFX89428.1 - 2.8e-17 62.4 1.0 2.9e-16 59.0 0.7 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Tol_Tol_Ttg2 PF05494.7 KFX89428.1 - 0.046 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 PNTB PF02233.11 KFX89429.1 - 9.8e-168 558.6 22.7 9.8e-168 558.6 15.8 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KFX89429.1 - 5.7e-54 182.1 1.8 1.1e-53 181.2 1.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFX89429.1 - 1.4e-38 131.9 0.0 4.5e-38 130.3 0.0 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KFX89429.1 - 9.9e-32 108.9 3.2 9.9e-32 108.9 2.2 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KFX89429.1 - 0.0055 15.8 0.4 0.85 8.7 0.0 2.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 KFX89429.1 - 0.012 15.3 0.3 0.05 13.3 0.2 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain GIDA PF01134.17 KFX89429.1 - 0.071 11.9 1.1 0.15 10.9 0.8 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_31 PF13847.1 KFX89429.1 - 0.077 12.5 0.1 0.63 9.6 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Pyr_redox_2 PF07992.9 KFX89429.1 - 0.11 12.3 2.1 0.13 12.0 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 KFX89430.1 - 6.6e-05 21.9 0.2 0.00011 21.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89430.1 - 0.02 14.8 15.5 0.045 13.6 10.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_N PF02837.13 KFX89431.1 - 8.6e-26 90.4 0.0 3.1e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFX89431.1 - 4e-13 48.9 0.0 1.8e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFX89431.1 - 9.9e-11 42.0 0.1 6.2e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFX89431.1 - 0.00034 20.8 0.3 0.00093 19.4 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DUF4066 PF13278.1 KFX89432.1 - 3e-19 68.8 0.0 4.5e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX89432.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Mre11_DNA_bind PF04152.9 KFX89433.1 - 3.9e-54 183.1 0.2 6.5e-54 182.4 0.1 1.4 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KFX89433.1 - 1e-24 87.0 2.1 1.4e-24 86.6 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX89433.1 - 2.4e-06 27.4 0.4 6.8e-06 25.9 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF605 PF04652.11 KFX89433.1 - 0.3 10.4 11.9 0.46 9.8 8.3 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_S19 PF00203.16 KFX89434.1 - 6.3e-23 80.1 0.1 8.7e-23 79.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SnoaL_2 PF12680.2 KFX89435.1 - 0.035 14.4 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain DUF2848 PF11010.3 KFX89439.1 - 0.099 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) AKNA PF12443.3 KFX89439.1 - 0.15 12.0 5.1 9.7 6.2 0.4 3.3 3 0 0 3 3 3 0 AT-hook-containing transcription factor DUF904 PF06005.7 KFX89439.1 - 0.53 10.6 0.1 0.53 10.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) PEP-utilisers_N PF05524.8 KFX89439.1 - 0.58 9.9 6.4 0.53 10.0 0.1 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal ArfGap PF01412.13 KFX89442.1 - 1e-37 128.4 0.1 1e-37 128.4 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 KFX89442.1 - 0.0032 17.2 0.0 0.019 14.8 0.0 2.4 1 0 0 1 1 1 1 UBA/TS-N domain AA_permease PF00324.16 KFX89444.1 - 6.8e-120 400.6 35.3 7.6e-120 400.4 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX89444.1 - 3.4e-31 108.2 39.5 4e-31 107.9 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_33 PF13671.1 KFX89445.1 - 6e-22 78.0 0.0 7.1e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX89445.1 - 4.2e-09 37.2 0.1 5.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX89445.1 - 2.1e-07 31.2 0.0 2.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX89445.1 - 1.1e-06 27.9 0.0 1.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin SKI PF01202.17 KFX89445.1 - 0.00017 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase CPT PF07931.7 KFX89445.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 KFX89445.1 - 0.012 15.2 0.5 0.15 11.6 0.3 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase DUF1792 PF08759.6 KFX89445.1 - 0.023 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) G-alpha PF00503.15 KFX89445.1 - 0.036 12.7 0.1 0.058 12.0 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.1 KFX89445.1 - 0.037 14.1 0.1 0.046 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KFX89445.1 - 0.097 12.3 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KFX89445.1 - 0.11 11.3 0.1 0.28 9.9 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 KFX89445.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KFX89445.1 - 0.26 10.7 1.1 0.29 10.5 0.8 1.4 1 1 0 1 1 1 0 AAA-like domain MFS_1 PF07690.11 KFX89446.1 - 1.5e-29 102.8 28.1 4e-16 58.6 6.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX89446.1 - 1.2e-10 40.4 19.0 0.00054 18.4 5.6 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 KFX89446.1 - 0.0026 16.3 9.1 0.0026 16.3 6.3 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFX89446.1 - 0.007 16.1 9.9 0.053 13.3 0.2 3.8 3 1 1 4 4 4 2 MFS_1 like family ATG22 PF11700.3 KFX89446.1 - 0.3 9.5 21.2 0.0037 15.8 5.7 2.5 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like E1-E2_ATPase PF00122.15 KFX89446.1 - 0.68 8.9 5.0 6 5.8 3.5 2.2 1 1 0 1 1 1 0 E1-E2 ATPase OATP PF03137.15 KFX89446.1 - 2.9 5.8 9.1 0.12 10.3 0.8 2.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.27 KFX89447.1 - 8.1e-31 104.7 0.3 3.3e-09 36.2 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX89447.1 - 0.00011 21.9 0.6 0.081 12.6 0.1 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX89447.1 - 0.00027 19.2 0.1 0.00038 18.7 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KFX89447.1 - 0.00059 18.7 0.3 0.35 9.6 0.1 2.4 1 1 2 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.6 KFX89447.1 - 0.004 15.9 0.0 0.094 11.4 0.0 2.3 1 1 1 2 2 2 1 Nup133 N terminal like PQQ_2 PF13360.1 KFX89447.1 - 0.0089 15.5 1.0 0.099 12.0 0.7 2.4 1 1 1 2 2 2 1 PQQ-like domain Peptidase_S9_N PF02897.10 KFX89447.1 - 0.042 12.4 1.4 0.081 11.4 0.4 1.7 1 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Gmad1 PF10647.4 KFX89447.1 - 0.048 13.0 1.0 0.17 11.2 0.1 1.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain FTHFS PF01268.14 KFX89448.1 - 5e-257 853.3 0.5 6.9e-257 852.8 0.3 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KFX89448.1 - 1.6e-67 225.6 1.8 1.6e-67 225.6 1.2 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFX89448.1 - 1.8e-39 134.3 0.7 3.5e-39 133.4 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 KFX89448.1 - 0.011 15.1 0.1 0.034 13.5 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HORMA PF02301.13 KFX89449.1 - 5.3e-49 166.5 0.3 6.1e-49 166.3 0.2 1.0 1 0 0 1 1 1 1 HORMA domain DUF1068 PF06364.7 KFX89449.1 - 0.019 14.5 0.2 0.03 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF2066 PF09839.4 KFX89449.1 - 0.037 13.1 0.3 0.15 11.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) Alba PF01918.16 KFX89449.1 - 0.17 11.5 1.0 0.31 10.6 0.6 1.6 1 1 0 1 1 1 0 Alba SspB PF04386.8 KFX89449.1 - 0.64 9.6 4.7 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Stringent starvation protein B GTP_EFTU PF00009.22 KFX89450.1 - 8.1e-48 162.3 0.0 1.7e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KFX89450.1 - 4e-39 132.8 6.6 6.4e-39 132.1 4.6 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KFX89450.1 - 3.4e-19 68.4 0.0 6.1e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX89450.1 - 3e-07 30.4 0.1 6.4e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 KFX89450.1 - 8.9e-06 25.1 0.0 3.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 KFX89450.1 - 4.6e-05 23.3 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX89450.1 - 0.003 16.8 0.0 0.0073 15.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 KFX89450.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II adh_short PF00106.20 KFX89451.1 - 2.3e-16 60.1 0.1 9e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX89451.1 - 2.5e-05 24.0 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX89451.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX89451.1 - 0.00075 19.0 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HMG_box PF00505.14 KFX89453.1 - 1.8e-15 56.9 0.8 4e-15 55.8 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX89453.1 - 6.4e-15 55.2 0.9 1.6e-14 54.0 0.6 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KFX89453.1 - 2.2e-10 40.5 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX89453.1 - 6.5e-08 32.2 0.5 1.8e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 KFX89455.1 - 2e-65 220.5 0.0 2.3e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89455.1 - 1.9e-31 109.1 0.0 2.4e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX89455.1 - 2e-05 23.7 0.0 7.4e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX89455.1 - 0.0003 19.8 0.0 0.015 14.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KFX89455.1 - 0.00035 20.3 0.0 0.00066 19.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX89455.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KFX89455.1 - 0.12 11.1 0.3 0.17 10.6 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aldo_ket_red PF00248.16 KFX89458.1 - 4.9e-65 219.1 0.0 5.6e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1498 PF07385.7 KFX89458.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) IDO PF01231.13 KFX89459.1 - 4.1e-167 555.9 0.0 4.7e-167 555.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase p450 PF00067.17 KFX89462.1 - 8.2e-82 275.1 0.0 9.7e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane_5 PF13346.1 KFX89462.1 - 0.043 13.1 0.4 0.076 12.2 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ASL_C PF08328.6 KFX89462.1 - 0.13 12.1 0.2 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal PMT PF02366.13 KFX89464.1 - 5e-81 271.6 16.8 6.6e-81 271.2 11.6 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFX89464.1 - 4.7e-18 65.4 1.5 6.4e-17 61.7 0.3 2.1 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 KFX89464.1 - 0.00022 21.1 12.6 0.00091 19.1 8.4 2.2 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Zn_clus PF00172.13 KFX89467.1 - 0.0051 16.6 9.6 0.0051 16.6 6.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KFX89467.1 - 0.013 15.2 0.0 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 PAS fold Flavokinase PF01687.12 KFX89468.1 - 1.2e-35 122.1 0.0 1.3e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase SelP_N PF04592.9 KFX89469.1 - 0.32 10.3 5.9 0.33 10.2 4.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.11 KFX89469.1 - 1.5 8.1 5.0 1.6 7.9 3.5 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 KFX89469.1 - 2.3 7.1 5.5 2.3 7.1 3.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4336 PF14234.1 KFX89476.1 - 2.6e-16 59.6 0.0 9.1e-12 44.7 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4166 PF13761.1 KFX89476.1 - 0.062 13.1 0.1 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4166) Pil1 PF13805.1 KFX89479.1 - 7.9e-150 497.4 0.2 9.9e-150 497.1 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KFX89479.1 - 0.029 13.6 2.2 0.094 12.0 1.5 1.8 1 1 0 1 1 1 0 FAM92 protein LSM PF01423.17 KFX89480.1 - 2.7e-05 23.6 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain XPG_N PF00752.12 KFX89481.1 - 1.3e-33 115.3 0.0 4.4e-33 113.5 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFX89481.1 - 2.3e-26 91.6 0.0 5.7e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region DSS1_SEM1 PF05160.8 KFX89481.1 - 0.0074 16.0 1.6 0.0074 16.0 1.1 5.6 6 0 0 6 6 6 1 DSS1/SEM1 family UIM PF02809.15 KFX89481.1 - 0.0075 15.7 0.7 0.0075 15.7 0.5 3.6 3 0 0 3 3 3 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 KFX89481.1 - 0.0089 16.2 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CorA PF01544.13 KFX89481.1 - 3.1 6.7 4.8 5.9 5.8 3.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DnaJ-X PF14308.1 KFX89483.1 - 7.8e-71 237.5 1.9 7.8e-71 237.5 1.3 2.1 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KFX89483.1 - 1e-24 86.0 0.4 2.3e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.12 KFX89483.1 - 1.6e-13 50.2 0.0 4e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KFX89483.1 - 1.8e-11 43.9 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX89483.1 - 6.5e-05 21.9 0.2 0.00086 18.2 0.0 2.6 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Macro PF01661.16 KFX89483.1 - 0.06 13.2 0.0 0.25 11.2 0.0 2.1 1 0 0 1 1 1 0 Macro domain adh_short PF00106.20 KFX89483.1 - 0.12 12.2 0.5 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Cyt-b5 PF00173.23 KFX89485.1 - 9.7e-16 57.3 0.0 1.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TRM PF02005.11 KFX89486.1 - 8e-106 354.1 0.0 2e-92 310.0 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.21 KFX89486.1 - 5.6e-08 32.7 0.1 1.5e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 FHA domain Met_10 PF02475.11 KFX89486.1 - 0.097 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Met-10+ like-protein Inositol_P PF00459.20 KFX89487.1 - 2e-66 224.0 0.0 2.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1134 PF06577.7 KFX89487.1 - 0.043 13.3 0.1 0.083 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Antimicrobial_9 PF08104.6 KFX89487.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Ponericin L family Adaptin_binding PF10199.4 KFX89488.1 - 0.54 10.5 13.4 0.8 9.9 6.7 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SMC_Nse1 PF07574.8 KFX89489.1 - 9.4e-38 129.8 0.1 1.1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KFX89489.1 - 5.7e-14 51.8 7.5 8.8e-14 51.2 5.2 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 KFX89489.1 - 0.019 14.7 6.4 0.03 14.1 4.5 1.3 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KFX89489.1 - 0.92 9.5 5.2 2.8 7.9 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KFX89489.1 - 9.2 6.0 8.2 29 4.4 5.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF500 PF04366.7 KFX89490.1 - 8.9e-42 141.5 0.1 1.5e-41 140.7 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) WD40 PF00400.27 KFX89491.1 - 6.3e-25 86.1 25.6 1e-09 37.8 0.0 11.2 12 0 0 12 12 12 7 WD domain, G-beta repeat CHCH PF06747.8 KFX89495.1 - 1.3e-06 28.1 3.9 2.1e-06 27.4 2.7 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KFX89495.1 - 0.038 14.1 3.5 0.054 13.6 1.5 1.9 1 1 1 2 2 2 0 GCK domain DUF2413 PF10310.4 KFX89495.1 - 4.1 6.1 11.0 0.072 11.9 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) MCM_N PF14551.1 KFX89496.1 - 0.1 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain DUF2396 PF09654.5 KFX89497.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2396) Pkinase PF00069.20 KFX89502.1 - 2.6e-05 23.5 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain His_Phos_1 PF00300.17 KFX89502.1 - 0.032 14.3 0.0 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 KFX89503.1 - 2.5e-06 26.8 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 KFX89503.1 - 0.0067 15.7 0.0 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_Tyr PF07714.12 KFX89503.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase NmrA PF05368.8 KFX89504.1 - 9.5e-23 80.6 0.0 1.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX89504.1 - 8.9e-12 45.3 0.2 2e-11 44.2 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KFX89504.1 - 1.8e-05 23.8 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KFX89504.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3328 PF11807.3 KFX89506.1 - 1.7e-52 178.2 0.1 2.1e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) U-box PF04564.10 KFX89514.1 - 1.2e-05 25.2 0.0 1.2e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KFX89514.1 - 0.039 13.4 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Myb_DNA-binding PF00249.26 KFX89517.1 - 1.8e-22 79.1 0.6 1e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX89517.1 - 1.4e-17 63.5 1.0 7.6e-12 45.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KFX89517.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 KFX89517.1 - 0.078 12.6 0.9 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain MARVEL PF01284.18 KFX89519.1 - 8.1e-12 45.1 16.0 1.2e-11 44.6 11.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4246 PF14033.1 KFX89521.1 - 5.4e-131 437.6 0.0 6.4e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PAN_3 PF08277.7 KFX89523.1 - 1.3e-09 37.5 10.9 0.0087 15.6 0.4 3.7 3 0 0 3 3 3 3 PAN-like domain PAN_4 PF14295.1 KFX89523.1 - 2.4e-06 27.1 16.4 0.022 14.4 0.2 3.9 3 0 0 3 3 3 3 PAN domain LIM PF00412.17 KFX89523.1 - 0.065 13.3 5.0 16 5.6 0.2 3.8 3 0 0 3 3 3 0 LIM domain PAN_2 PF08276.6 KFX89523.1 - 0.26 11.1 18.8 0.83 9.5 0.9 3.7 3 0 0 3 3 3 0 PAN-like domain Pectate_lyase_3 PF12708.2 KFX89524.1 - 2.9e-69 233.6 9.8 6e-52 176.9 2.5 3.4 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KFX89524.1 - 6.3e-06 25.5 0.5 0.14 11.6 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF1090 PF06476.7 KFX89525.1 - 0.84 9.3 4.4 0.7 9.5 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) NAD_binding_10 PF13460.1 KFX89528.1 - 4.4e-06 26.8 0.0 7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX89528.1 - 0.007 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFX89528.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 KFX89528.1 - 0.11 12.1 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 KR domain Sugar_tr PF00083.19 KFX89529.1 - 3.4e-78 263.2 18.6 4e-78 263.0 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89529.1 - 5.3e-22 78.0 27.9 1.2e-21 76.8 18.1 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KFX89530.1 - 0.092 13.1 18.5 0.24 11.8 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX89530.1 - 1.7 9.1 14.0 0.044 14.1 2.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.14 KFX89534.1 - 1.9e-10 40.3 0.0 2.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFX89534.1 - 5.5e-06 26.3 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX89534.1 - 1.9e-05 24.6 0.1 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX89534.1 - 3.8e-05 24.0 0.0 0.00021 21.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX89534.1 - 0.00013 20.9 1.0 0.00053 19.0 0.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX89534.1 - 0.00025 19.6 0.0 0.00034 19.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KFX89534.1 - 0.00033 19.6 0.0 0.00057 18.8 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KFX89534.1 - 0.0022 17.1 1.2 0.0077 15.3 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFX89534.1 - 0.0032 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX89534.1 - 0.022 13.6 0.1 0.072 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KFX89534.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.10 KFX89534.1 - 0.095 10.8 0.0 0.23 9.5 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.16 KFX89534.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M24 PF00557.19 KFX89535.1 - 7.2e-44 149.8 0.2 8.7e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KFX89535.1 - 3.5e-05 23.5 4.9 9.1e-05 22.2 3.4 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KFX89535.1 - 0.4 10.3 3.1 0.97 9.1 2.1 1.7 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.9 KFX89536.1 - 2.1e-54 183.1 10.9 2.3e-54 182.9 7.5 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 KFX89537.1 - 1.6e-37 126.0 2.5 7.9e-10 38.2 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFX89537.1 - 9.2e-05 20.7 0.2 0.056 11.5 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Fungal_trans PF04082.13 KFX89540.1 - 1.3e-13 50.4 0.2 2e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 KFX89540.1 - 2.2 6.4 35.0 3.1 5.9 24.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RasGAP PF00616.14 KFX89544.1 - 1.9e-42 145.1 0.0 5.3e-42 143.7 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFX89544.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 C2 domain Toxin_18 PF08087.6 KFX89548.1 - 1.1 9.1 7.3 7.1 6.5 0.1 2.7 2 0 0 2 2 2 0 Conotoxin O-superfamily UPF0506 PF11703.3 KFX89548.1 - 1.3 8.9 7.9 33 4.5 5.7 2.3 1 1 1 2 2 2 0 UPF0506 Ribosomal_S2 PF00318.15 KFX89553.1 - 5.1e-48 163.0 0.0 9.6e-48 162.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 KFX89553.1 - 2.3e-39 132.9 9.7 9.2e-11 41.3 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KFX89553.1 - 7e-10 38.4 0.0 2.1e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 PB1 domain HEAT_2 PF13646.1 KFX89554.1 - 1.4e-18 66.9 13.7 9.7e-08 32.2 0.1 8.4 4 2 3 7 7 7 4 HEAT repeats HEAT PF02985.17 KFX89554.1 - 1.9e-17 61.6 9.7 0.002 18.0 0.0 10.1 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 KFX89554.1 - 1e-15 57.7 19.7 1.6e-08 34.7 0.2 9.6 6 2 4 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFX89554.1 - 1e-10 41.8 0.0 0.067 13.5 0.0 5.8 3 1 3 6 6 6 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KFX89554.1 - 1.2e-08 34.0 1.0 5.9e-07 28.5 0.0 3.6 3 1 2 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KFX89554.1 - 1.4e-07 31.1 1.3 0.033 13.5 0.0 4.6 3 2 2 5 5 5 2 CLASP N terminal RIX1 PF08167.7 KFX89554.1 - 0.00012 21.8 0.3 0.11 12.1 0.0 4.6 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis DUF4042 PF13251.1 KFX89554.1 - 0.00025 20.5 0.3 0.91 8.9 0.2 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) Arm PF00514.18 KFX89554.1 - 0.0015 18.2 4.4 0.41 10.5 0.1 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KFX89554.1 - 0.056 13.3 1.6 0.32 10.9 0.1 3.2 2 1 1 3 3 3 0 Importin-beta N-terminal domain DALR_1 PF05746.10 KFX89554.1 - 1 9.3 7.3 6.7 6.6 0.0 4.4 3 1 1 4 4 4 0 DALR anticodon binding domain adh_short PF00106.20 KFX89555.1 - 3.5e-19 69.3 0.1 9.2e-19 67.9 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX89555.1 - 7.7e-12 45.2 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX89555.1 - 1.2e-06 28.5 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX89555.1 - 3.1e-05 23.5 0.0 5.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX89555.1 - 0.00018 21.5 0.2 0.00073 19.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX89555.1 - 0.00034 19.5 0.0 0.00049 19.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KFX89555.1 - 0.0058 16.9 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX89555.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3842 PF12953.2 KFX89555.1 - 0.024 14.7 0.2 0.072 13.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) DUF3940 PF13076.1 KFX89555.1 - 0.075 12.5 0.7 0.12 11.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) NAD_binding_4 PF07993.7 KFX89555.1 - 0.089 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.14 KFX89555.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.13 KFX89556.1 - 1.1e-05 25.2 8.7 1.9e-05 24.4 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX89556.1 - 2e-05 23.3 0.1 3.3e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain PTPA PF03095.10 KFX89563.1 - 8.3e-110 366.6 0.0 9.9e-110 366.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Aminotran_3 PF00202.16 KFX89564.1 - 7e-25 87.5 0.0 9.4e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ubiquitin PF00240.18 KFX89566.1 - 7.7e-21 73.2 0.4 8.7e-21 73.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFX89566.1 - 1.7e-10 40.4 0.4 1.8e-10 40.3 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KFX89566.1 - 0.00044 20.0 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFX89566.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 KFX89566.1 - 0.014 15.5 0.1 0.024 14.8 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain MPP6 PF10175.4 KFX89566.1 - 0.045 14.1 0.2 0.072 13.4 0.1 1.3 1 1 0 1 1 1 0 M-phase phosphoprotein 6 MFS_1 PF07690.11 KFX89567.1 - 1.6e-05 23.8 6.4 1.9e-05 23.5 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89567.1 - 4.8e-05 22.1 5.2 5.7e-05 21.8 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Caps_synth_CapC PF14102.1 KFX89567.1 - 0.55 10.3 7.1 0.79 9.8 4.9 1.2 1 0 0 1 1 1 0 Capsule biosynthesis CapC MCR_C PF04609.7 KFX89569.1 - 0.16 10.7 1.5 1.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Prominin PF05478.6 KFX89569.1 - 2 5.8 19.9 1.9 5.8 5.8 3.6 2 1 0 3 3 3 0 Prominin PABP PF00658.13 KFX89570.1 - 2.6e-25 87.8 3.4 1e-18 66.7 0.3 2.7 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RINGv PF12906.2 KFX89570.1 - 6.6e-16 58.0 8.8 1.1e-15 57.3 6.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KFX89570.1 - 0.043 13.6 7.9 0.073 12.9 5.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KFX89570.1 - 2.8 7.5 6.7 4.7 6.8 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFX89570.1 - 7.5 6.5 5.8 14 5.6 4.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Lactamase_B PF00753.22 KFX89571.1 - 1.5e-17 63.8 0.0 4.7e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX89571.1 - 8.6e-05 22.1 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BTB_2 PF02214.17 KFX89573.1 - 6.1e-07 29.5 0.0 0.00034 20.7 0.0 3.1 3 0 0 3 3 3 2 BTB/POZ domain Cu_bind_like PF02298.12 KFX89574.1 - 0.099 12.4 0.3 0.56 10.0 0.2 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Cupredoxin_1 PF13473.1 KFX89574.1 - 0.12 12.3 0.1 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain WD40 PF00400.27 KFX89577.1 - 5.7e-54 178.1 16.8 1e-08 34.7 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KFX89577.1 - 1.3e-10 40.8 0.1 2.9e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX89577.1 - 1.1e-08 34.5 0.1 3.9e-08 32.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFX89577.1 - 6.9e-06 24.4 8.1 0.41 8.7 0.1 5.1 3 2 3 6 6 6 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KFX89577.1 - 0.00068 19.3 0.1 2.1 8.1 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KFX89577.1 - 0.0027 17.2 2.2 0.61 9.4 0.1 3.0 1 1 0 1 1 1 1 PQQ-like domain DUF1629 PF07791.6 KFX89577.1 - 0.19 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) Fungal_trans PF04082.13 KFX89580.1 - 8.1e-29 100.2 0.0 1.3e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89580.1 - 1.1e-09 38.0 10.9 1.7e-09 37.3 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridox_oxidase PF01243.15 KFX89582.1 - 3.4e-08 33.3 0.4 2.1e-07 30.8 0.1 2.1 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KFX89582.1 - 0.00048 20.3 0.6 0.0011 19.2 0.4 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CLTH PF10607.4 KFX89583.1 - 6.3e-33 113.5 0.1 1.6e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Pyr_redox_2 PF07992.9 KFX89583.1 - 2.4e-21 76.5 0.0 3.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX89583.1 - 4.4e-14 52.6 0.0 1.7e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase LisH PF08513.6 KFX89583.1 - 1.6e-07 30.8 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 LisH EF-hand_1 PF00036.27 KFX89583.1 - 1e-05 24.4 0.3 2.3e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX89583.1 - 0.00022 20.8 0.3 0.00062 19.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KFX89583.1 - 0.00036 20.6 0.1 0.001 19.1 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFX89583.1 - 0.00038 19.6 0.4 0.00078 18.6 0.3 1.5 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 KFX89583.1 - 0.014 15.4 0.1 7 6.6 0.0 2.9 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Toprim PF01751.17 KFX89583.1 - 0.093 12.7 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Toprim domain Glyco_hydro_28 PF00295.12 KFX89585.1 - 1.8e-87 293.3 18.9 2.2e-87 293.0 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KFX89585.1 - 2.1e-05 24.3 17.5 2.1e-05 24.3 12.1 1.9 3 0 0 3 3 3 1 Right handed beta helix region MFS_1 PF07690.11 KFX89586.1 - 3.1e-44 151.1 59.9 1.7e-43 148.6 40.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX89586.1 - 6.5e-24 84.0 27.2 9.7e-24 83.5 18.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX89586.1 - 2.6e-13 49.3 17.2 2.6e-13 49.3 12.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Prenyltransf PF01255.14 KFX89587.1 - 3.9e-75 251.7 0.0 1.6e-72 243.2 0.0 2.9 2 1 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Terpene_synth_C PF03936.11 KFX89587.1 - 0.031 13.5 0.0 0.082 12.1 0.0 1.7 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ANTAR PF03861.9 KFX89587.1 - 0.04 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 ANTAR domain Crystall_3 PF08964.5 KFX89588.1 - 0.0033 17.1 0.0 0.046 13.4 0.0 2.1 2 0 0 2 2 2 1 Beta/Gamma crystallin Crystall PF00030.14 KFX89588.1 - 0.011 15.5 0.1 0.84 9.5 0.0 2.5 2 1 0 2 2 2 0 Beta/Gamma crystallin adh_short PF00106.20 KFX89589.1 - 9e-15 54.9 3.1 6.3e-13 48.9 2.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX89589.1 - 5.8e-10 39.3 2.0 5.2e-09 36.2 1.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX89589.1 - 6.4e-08 32.4 0.4 1.3e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 KFX89589.1 - 0.0004 19.4 0.1 0.00066 18.7 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFX89589.1 - 0.0028 17.7 0.1 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KFX89589.1 - 0.0034 16.3 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.16 KFX89591.1 - 2e-64 217.1 0.0 2.7e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 KFX89591.1 - 7.5e-31 107.1 0.1 2e-30 105.7 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AHH PF14412.1 KFX89591.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH p450 PF00067.17 KFX89592.1 - 1.3e-67 228.3 0.0 2.1e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFX89592.1 - 2.3e-37 128.5 24.2 2.3e-37 128.5 16.8 5.5 2 2 3 5 5 5 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 KFX89592.1 - 9.9e-34 116.6 38.4 9.9e-34 116.6 26.6 2.6 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 KFX89592.1 - 1.5e-21 76.4 0.0 2.7e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89592.1 - 1.9e-05 24.4 11.6 3.5e-05 23.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 KFX89593.1 - 7.7e-72 242.5 0.0 1e-71 242.0 0.0 1.2 1 0 0 1 1 1 1 Amidase LIP PF03583.9 KFX89594.1 - 3.1e-65 220.2 1.1 4.1e-65 219.8 0.8 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KFX89594.1 - 7.2e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX89594.1 - 2.7e-06 26.7 0.2 0.00018 20.7 0.0 2.7 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX89594.1 - 4.5e-06 26.4 0.3 1.3e-05 24.9 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX89594.1 - 0.00026 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 KFX89594.1 - 0.0037 16.5 0.0 0.0071 15.6 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 KFX89594.1 - 0.0082 15.8 0.2 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Cutinase Abhydrolase_1 PF00561.15 KFX89594.1 - 0.095 12.2 0.1 0.22 11.0 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold BNR PF02012.15 KFX89595.1 - 0.74 9.8 8.4 4.9 7.4 1.0 3.8 3 0 0 3 3 3 0 BNR/Asp-box repeat Helicase_C PF00271.26 KFX89596.1 - 0.00075 19.3 0.0 0.00092 19.0 0.0 1.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_7 PF00840.15 KFX89597.1 - 1.2e-83 280.9 27.9 7.4e-28 97.0 5.6 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 Peptidase_A4 PF01828.12 KFX89598.1 - 4.7e-81 270.8 14.6 5.6e-81 270.5 10.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family PhnA PF03831.9 KFX89598.1 - 0.14 11.6 0.5 4.3 6.8 0.0 2.6 2 0 0 2 2 2 0 PhnA protein HLH PF00010.21 KFX89605.1 - 5.5e-17 61.2 0.2 1.1e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 KFX89605.1 - 0.063 13.2 0.7 0.063 13.2 0.5 1.8 2 0 0 2 2 2 0 bZIP transcription factor Choline_kinase PF01633.15 KFX89607.1 - 2.1e-48 164.6 0.0 2.2e-47 161.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KFX89607.1 - 6.1e-10 39.2 1.4 8.2e-10 38.8 0.2 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFX89607.1 - 0.017 14.2 0.0 0.038 13.1 0.0 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase PEX11 PF05648.9 KFX89611.1 - 5.9e-72 241.5 0.1 6.7e-72 241.3 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) p450 PF00067.17 KFX89614.1 - 3.4e-52 177.5 0.0 4.4e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rad4 PF03835.10 KFX89615.1 - 1.7e-30 105.3 0.6 1.7e-30 105.3 0.4 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KFX89615.1 - 7.6e-27 92.8 0.1 1.5e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KFX89615.1 - 8.1e-14 50.8 0.0 2e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFX89615.1 - 1.1e-10 41.6 0.0 1.1e-10 41.6 0.0 2.8 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 GHL6 PF14871.1 KFX89615.1 - 0.065 13.2 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Adeno_terminal PF02459.10 KFX89615.1 - 0.4 8.7 3.6 0.67 8.0 2.5 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Glyco_transf_17 PF04724.8 KFX89623.1 - 8.8e-43 146.6 5.0 1.2e-42 146.1 3.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Fungal_trans_2 PF11951.3 KFX89624.1 - 3.4e-09 35.8 0.5 5.3e-09 35.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89624.1 - 0.00011 22.0 8.6 0.00028 20.7 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4336 PF14234.1 KFX89625.1 - 3.2e-13 49.5 0.1 2.9e-08 33.2 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Aldo_ket_red PF00248.16 KFX89626.1 - 3.4e-49 167.1 0.0 4.1e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KFX89627.1 - 1.2e-42 145.8 47.1 1.2e-42 145.8 32.7 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89627.1 - 4.2e-08 32.2 12.5 4.2e-08 32.2 8.7 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter Sugar_tr PF00083.19 KFX89629.1 - 9.6e-83 278.2 30.7 1.1e-82 278.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89629.1 - 2.7e-26 92.1 43.5 1.4e-25 89.7 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.11 KFX89630.1 - 1.3e-37 129.8 0.0 1.7e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M35 PF02102.10 KFX89631.1 - 2.5e-93 312.5 18.7 3e-93 312.3 13.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 KFX89631.1 - 2e-06 27.3 1.9 5.6e-06 25.9 1.4 1.6 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 KFX89631.1 - 2.5e-05 24.7 0.7 4.5e-05 23.9 0.5 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Aldedh PF00171.17 KFX89635.1 - 1.6e-122 409.1 0.6 2e-122 408.8 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.11 KFX89635.1 - 1e-15 57.3 46.1 1e-15 57.3 31.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0093 PF03653.8 KFX89635.1 - 0.038 13.9 5.3 0.098 12.6 3.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) SurE PF01975.12 KFX89636.1 - 3.9e-39 134.0 0.0 5.3e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Transp_cyt_pur PF02133.10 KFX89637.1 - 2.9e-142 474.3 34.8 3.3e-142 474.1 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OTT_1508_deam PF14441.1 KFX89638.1 - 2e-09 37.4 0.0 3.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Epimerase PF01370.16 KFX89639.1 - 1.6e-15 57.1 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX89639.1 - 5.9e-08 31.9 0.1 5.1e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KFX89639.1 - 8.6e-06 24.6 0.0 1.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX89639.1 - 3.4e-05 23.9 0.1 0.00012 22.1 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX89639.1 - 0.0093 15.2 0.1 0.041 13.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 KFX89639.1 - 0.014 15.0 0.9 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 KFX89639.1 - 0.016 15.1 3.6 0.25 11.2 0.7 2.9 2 1 0 2 2 2 0 short chain dehydrogenase PT-VENN PF04829.8 KFX89639.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif SH3_3 PF08239.6 KFX89640.1 - 0.032 14.4 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain ABC_tran PF00005.22 KFX89641.1 - 3.5e-39 134.2 0.0 1.6e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX89641.1 - 5.3e-27 94.9 25.7 5.9e-24 84.9 7.6 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX89641.1 - 9e-15 55.3 0.6 1.6e-05 25.0 0.1 4.3 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 KFX89641.1 - 2.9e-10 39.7 1.5 0.032 13.4 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX89641.1 - 3.7e-07 29.5 1.0 0.025 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX89641.1 - 6.7e-07 29.4 0.3 0.00085 19.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KFX89641.1 - 7.2e-07 30.0 0.0 0.012 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KFX89641.1 - 7.5e-07 28.3 0.0 0.00091 18.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 KFX89641.1 - 7.5e-07 29.3 0.0 0.033 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFX89641.1 - 1.2e-05 25.6 0.0 0.062 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX89641.1 - 1.3e-05 24.4 0.1 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX89641.1 - 1.4e-05 25.4 0.6 0.15 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX89641.1 - 1.4e-05 24.5 0.3 0.13 11.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KFX89641.1 - 0.00013 21.8 0.6 0.04 13.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFX89641.1 - 0.00014 21.6 0.3 0.093 12.4 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KFX89641.1 - 0.00015 21.6 0.3 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 KFX89641.1 - 0.00016 21.6 0.1 0.71 9.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFX89641.1 - 0.00031 21.2 0.3 0.075 13.5 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_10 PF12846.2 KFX89641.1 - 0.00034 20.1 0.9 0.21 10.9 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 KFX89641.1 - 0.00034 20.1 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 KFX89641.1 - 0.0016 18.2 2.2 0.063 13.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 KFX89641.1 - 0.0018 18.1 4.3 0.25 11.2 0.3 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KFX89641.1 - 0.0031 17.7 0.2 0.38 10.9 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX89641.1 - 0.005 15.9 0.2 0.23 10.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFX89641.1 - 0.0083 15.8 0.5 0.12 12.1 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KFX89641.1 - 0.009 15.7 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase Adeno_IVa2 PF02456.10 KFX89641.1 - 0.011 14.4 0.1 0.79 8.3 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.7 KFX89641.1 - 0.011 15.3 0.0 3.2 7.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 KFX89641.1 - 0.012 14.5 0.0 5.9 5.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 KFX89641.1 - 0.014 14.9 0.3 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 KFX89641.1 - 0.031 13.4 0.5 8.9 5.4 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KFX89641.1 - 0.041 13.2 0.1 27 4.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KFX89641.1 - 0.045 13.9 0.1 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Guanylate_kin PF00625.16 KFX89641.1 - 0.052 12.9 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 1 0 Guanylate kinase cobW PF02492.14 KFX89641.1 - 0.06 12.7 1.9 0.91 8.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KFX89641.1 - 0.088 12.2 0.5 0.85 9.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KFX89641.1 - 0.16 11.4 0.5 18 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFX89641.1 - 0.19 11.4 0.3 13 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FAD_binding_3 PF01494.14 KFX89642.1 - 1.5e-16 60.4 0.4 1.3e-14 54.0 0.3 2.8 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFX89642.1 - 0.0037 17.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.2 KFX89643.1 - 3.1e-90 296.6 4.3 1.8e-20 73.0 0.2 10.0 6 2 4 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89643.1 - 9.2e-70 227.1 16.3 1.9e-06 27.3 0.2 19.1 20 0 0 20 20 20 11 Ankyrin repeat Ank_3 PF13606.1 KFX89643.1 - 2.8e-58 188.0 15.6 0.00012 21.9 0.0 19.3 20 1 1 21 21 21 12 Ankyrin repeat Ank_4 PF13637.1 KFX89643.1 - 4.6e-52 173.5 1.4 6.7e-10 39.2 0.0 13.6 11 4 3 14 14 14 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX89643.1 - 4.9e-40 134.6 7.1 0.00027 21.0 0.1 13.1 7 5 6 13 13 13 8 Ankyrin repeats (many copies) Clr5 PF14420.1 KFX89643.1 - 5.7e-16 58.1 0.2 1.3e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain TGS PF02824.16 KFX89643.1 - 0.0096 15.7 0.0 0.036 13.8 0.0 2.1 1 0 0 1 1 1 1 TGS domain DUF2205 PF10224.4 KFX89646.1 - 3.4e-31 106.6 3.0 5.9e-31 105.8 2.1 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Spectrin PF00435.16 KFX89646.1 - 0.019 15.2 1.3 0.03 14.6 0.9 1.2 1 0 0 1 1 1 0 Spectrin repeat SapC PF07277.6 KFX89646.1 - 0.029 13.6 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 SapC Terpene_synth_C PF03936.11 KFX89646.1 - 0.038 13.2 0.1 0.048 12.8 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ApoO PF09769.4 KFX89646.1 - 0.29 10.8 2.2 0.94 9.1 1.5 1.9 1 1 0 1 1 1 0 Apolipoprotein O NDUF_B8 PF05821.6 KFX89648.1 - 6.7e-05 22.6 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DHDPS PF00701.17 KFX89654.1 - 1.4e-35 122.3 0.0 1.6e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 KFX89655.1 - 1.3e-11 45.0 0.5 5.4e-11 43.0 0.3 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HAD_2 PF13419.1 KFX89656.1 - 3.2e-17 63.2 0.0 4.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX89656.1 - 2.5e-08 33.5 0.0 4.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFX89656.1 - 1.3e-06 28.9 0.0 6.6e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KFX89656.1 - 0.095 12.3 0.0 3.7 7.1 0.3 2.2 1 1 0 2 2 2 0 NLI interacting factor-like phosphatase Pterin_bind PF00809.17 KFX89656.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Pterin binding enzyme Dehydratase_hem PF13816.1 KFX89659.1 - 0.084 11.8 0.0 0.099 11.6 0.0 1.0 1 0 0 1 1 1 0 Haem-containing dehydratase Oxidored_FMN PF00724.15 KFX89660.1 - 4.1e-84 282.4 0.0 1.7e-49 168.6 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 KFX89661.1 - 1.9e-21 76.1 0.4 5.1e-21 74.7 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89661.1 - 3.2e-07 30.1 10.9 6.2e-07 29.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 KFX89661.1 - 0.058 13.2 1.9 0.16 11.8 1.3 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CCDC92 PF14916.1 KFX89661.1 - 0.081 12.5 0.5 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain of unknown function adh_short_C2 PF13561.1 KFX89662.1 - 6.1e-28 98.2 0.1 7.3e-28 97.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX89662.1 - 7.5e-27 94.2 2.9 9.7e-27 93.9 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX89662.1 - 5.1e-11 42.5 1.3 6.9e-11 42.1 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX89662.1 - 0.00091 18.7 0.1 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX89662.1 - 0.0022 18.0 1.2 0.028 14.4 0.8 2.1 1 1 0 1 1 1 1 NADH(P)-binding Cellulase PF00150.13 KFX89663.1 - 1.7e-19 70.1 3.9 2.7e-19 69.4 2.7 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFX89663.1 - 2.4e-11 43.1 13.0 5.5e-11 41.9 9.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain DNMT1-RFD PF12047.3 KFX89663.1 - 0.00015 21.4 0.2 0.00067 19.3 0.1 1.8 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Cellulase-like PF12876.2 KFX89663.1 - 0.00064 20.1 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KFX89663.1 - 0.015 14.2 0.1 0.025 13.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KFX89663.1 - 0.047 12.7 0.1 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_10 PF00331.15 KFX89663.1 - 0.056 12.4 3.5 0.038 13.0 0.3 2.3 2 1 1 3 3 3 0 Glycosyl hydrolase family 10 AA_permease_2 PF13520.1 KFX89673.1 - 4.5e-49 167.1 60.3 5.6e-49 166.8 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX89673.1 - 1.6e-22 79.4 51.2 2.3e-22 78.9 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 KFX89674.1 - 9.3e-51 172.7 0.0 1.3e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KFX89676.1 - 1.2e-19 70.2 0.0 2.1e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89676.1 - 7.6e-07 28.9 11.0 1.3e-06 28.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX89677.1 - 3e-11 43.5 0.0 1.9e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX89677.1 - 3.7e-06 26.7 0.1 2.1e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFX89677.1 - 1.1e-05 25.3 0.0 6.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DDE_3 PF13358.1 KFX89678.1 - 1.3e-09 37.9 0.1 2.1e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 KFX89678.1 - 0.0043 17.8 0.3 0.012 16.4 0.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KFX89678.1 - 0.01 15.8 0.0 0.054 13.5 0.0 2.2 1 1 1 2 2 2 0 Transposase MBOAT_2 PF13813.1 KFX89679.1 - 1.2e-19 70.1 2.5 2.9e-19 68.9 1.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Amidase PF01425.16 KFX89680.1 - 2e-93 313.6 0.0 2.5e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1822 PF08852.6 KFX89681.1 - 0.056 12.2 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) V-ATPase_H_C PF11698.3 KFX89681.1 - 0.064 13.1 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H Fungal_trans_2 PF11951.3 KFX89682.1 - 1.3e-51 175.4 8.2 1.6e-51 175.0 5.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89682.1 - 4.3e-09 36.1 9.8 7.6e-09 35.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PS-DH PF14765.1 KFX89682.1 - 0.015 14.5 0.4 0.061 12.4 0.1 1.9 1 1 1 2 2 2 0 Polyketide synthase dehydratase DUF2072 PF09845.4 KFX89682.1 - 0.51 10.2 3.5 1 9.3 2.4 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Arginase PF00491.16 KFX89683.1 - 2.1e-92 309.3 0.0 2.4e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KFX89683.1 - 0.065 13.4 0.1 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MFS_1 PF07690.11 KFX89684.1 - 5.6e-47 160.1 29.7 7.8e-45 153.1 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89684.1 - 4.3e-17 61.8 28.1 8.8e-16 57.5 19.5 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFX89684.1 - 8.9e-06 24.1 2.4 1.4e-05 23.5 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KFX89684.1 - 0.00077 17.7 0.7 0.0013 16.9 0.5 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.10 KFX89684.1 - 0.021 13.5 14.4 0.0057 15.4 2.9 2.8 2 1 1 3 3 3 0 PUCC protein OATP PF03137.15 KFX89684.1 - 0.16 9.9 8.2 0.75 7.7 0.3 2.6 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.17 KFX89685.1 - 1.9e-179 596.8 0.5 2.1e-179 596.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFX89685.1 - 0.0029 16.8 0.0 0.96 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Glyco_hydro_11 PF00457.12 KFX89691.1 - 6.2e-83 276.6 17.5 7.2e-83 276.4 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.6 KFX89691.1 - 0.92 9.2 5.7 0.37 10.4 1.0 2.2 2 1 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Bac_rhamnosid PF05592.6 KFX89692.1 - 9.3e-44 149.4 1.5 1.6e-36 125.6 1.5 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase F5_F8_type_C PF00754.20 KFX89692.1 - 2.2e-12 46.9 0.4 2.4e-11 43.5 0.2 2.4 2 0 0 2 2 2 1 F5/8 type C domain DUF608 PF04685.8 KFX89692.1 - 1.6e-10 40.2 1.0 2.6e-10 39.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KFX89692.1 - 2.8e-06 26.2 0.1 4.6e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KFX89692.1 - 0.00023 19.9 0.1 0.00035 19.3 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.11 KFX89692.1 - 0.14 9.9 0.0 0.22 9.3 0.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Glyco_transf_90 PF05686.7 KFX89698.1 - 1.4e-14 53.6 2.7 1.2e-11 43.9 0.4 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L18e PF00828.14 KFX89699.1 - 2.9e-12 47.0 0.7 5.9e-12 46.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 4HBT_3 PF13622.1 KFX89700.1 - 1.2e-32 113.6 0.2 1.4e-32 113.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFX89700.1 - 8e-09 35.2 0.0 5.7e-05 22.7 0.0 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase Ribonuc_L-PSP PF01042.16 KFX89701.1 - 4.3e-18 65.2 0.0 8.9e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP PX PF00787.19 KFX89701.1 - 1e-17 63.9 0.3 2.2e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.1 KFX89701.1 - 0.046 13.4 0.4 0.098 12.4 0.3 1.5 1 0 0 1 1 1 0 Prefoldin subunit SnoaL PF07366.7 KFX89702.1 - 1.4e-29 102.2 0.1 1.6e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KFX89702.1 - 2.1e-16 60.1 0.1 2.5e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.7 KFX89702.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain DYW_deaminase PF14432.1 KFX89703.1 - 5.9e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Chromo PF00385.19 KFX89703.1 - 2.3e-05 23.9 4.4 0.031 13.9 0.2 2.7 1 1 1 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFX89703.1 - 0.072 13.0 3.7 1.1 9.1 0.2 2.6 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Ribosomal_S19e PF01090.14 KFX89704.1 - 1.7e-56 189.5 0.2 1.9e-56 189.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 KFX89705.1 - 1.6e-26 93.6 0.0 3.4e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX89705.1 - 1.6e-16 60.3 0.0 9.9e-16 57.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KFX89705.1 - 1.3e-11 44.2 0.0 4e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KFX89705.1 - 4.2e-11 42.8 0.0 3.6e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KFX89705.1 - 1.3e-06 28.7 0.1 3.6e-06 27.3 0.0 1.8 2 0 0 2 2 1 1 Thioesterase domain PGAP1 PF07819.8 KFX89705.1 - 2.8e-05 23.8 0.0 0.00015 21.4 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein PTPlike_phytase PF14566.1 KFX89705.1 - 3.2e-05 24.0 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 KFX89705.1 - 0.00079 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.20 KFX89705.1 - 0.0016 18.1 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 KFX89705.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.10 KFX89705.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 KFX89705.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 KFX89705.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KFX89705.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.3 KFX89705.1 - 0.057 13.2 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase DUF900 PF05990.7 KFX89705.1 - 0.083 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.6 KFX89705.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 KFX89705.1 - 0.093 12.1 0.0 5 6.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KFX89705.1 - 0.093 11.9 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF676 PF05057.9 KFX89705.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3632 PF12311.3 KFX89706.1 - 6.9e-25 87.9 0.0 8.6e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.6 KFX89707.1 - 8.6e-30 103.7 0.3 2.1e-29 102.4 0.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kelch_4 PF13418.1 KFX89711.1 - 3.7e-33 113.0 12.2 1.1e-06 28.3 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFX89711.1 - 2e-31 107.4 9.7 8.1e-09 35.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFX89711.1 - 1.3e-28 98.5 20.4 5.7e-08 32.7 0.1 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KFX89711.1 - 2.2e-28 97.2 9.0 1e-08 34.9 1.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KFX89711.1 - 2.1e-26 91.1 6.1 3.1e-07 29.8 0.3 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KFX89711.1 - 1.4e-19 68.9 10.0 2.9e-06 26.8 0.5 6.5 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KFX89711.1 - 0.037 12.7 0.3 0.68 8.5 0.0 3.0 4 0 0 4 4 4 0 Recombination activating protein 2 Filament PF00038.16 KFX89711.1 - 7.3 5.9 90.9 1.9 7.8 27.3 5.2 2 1 3 5 5 5 0 Intermediate filament protein LRR_4 PF12799.2 KFX89712.1 - 1.1e-08 34.4 6.0 3.2e-05 23.4 0.4 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX89712.1 - 3.7e-08 33.0 1.1 1.1e-07 31.4 0.8 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KFX89712.1 - 0.036 14.0 3.9 9.9 6.6 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KFX89712.1 - 0.1 12.8 3.0 7.5 7.2 0.3 3.6 3 0 0 3 3 3 0 Leucine rich repeat Phosducin PF02114.11 KFX89713.1 - 2.7e-10 39.4 0.1 4.1e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin alpha-hel2 PF14456.1 KFX89713.1 - 0.046 12.4 0.1 0.07 11.8 0.1 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Ribosomal_S27e PF01667.12 KFX89714.1 - 5.9e-29 99.3 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KFX89714.1 - 0.0066 16.2 1.1 0.0077 16.0 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 KFX89714.1 - 0.1 12.0 0.5 0.19 11.2 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger Proteasome PF00227.21 KFX89717.1 - 5.1e-32 110.6 0.0 5.7e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.15 KFX89718.1 - 6.3e-63 211.8 9.3 1.4e-62 210.7 5.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX89718.1 - 5.2e-46 156.4 10.7 7.3e-46 155.9 4.8 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX89718.1 - 8.4e-33 114.5 0.0 1.1e-31 110.9 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX89718.1 - 1.5e-21 76.1 0.0 3e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFX89718.1 - 1.9e-18 65.6 0.0 5.5e-18 64.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFX89718.1 - 1.2e-17 64.7 0.0 3.1e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX89718.1 - 3.3e-08 33.4 0.6 3.5e-06 26.7 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFX89718.1 - 0.023 14.9 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Proteasome_A_N PF10584.4 KFX89718.1 - 0.094 12.0 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature 14-3-3 PF00244.15 KFX89720.1 - 4.2e-115 382.7 1.7 4.2e-115 382.7 1.2 1.3 2 0 0 2 2 2 1 14-3-3 protein TPR_12 PF13424.1 KFX89720.1 - 0.0028 17.5 1.8 0.55 10.2 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4085 PF13315.1 KFX89720.1 - 0.021 14.2 0.2 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 KFX89720.1 - 0.06 13.3 0.2 15 5.6 0.0 3.1 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain TP_methylase PF00590.15 KFX89723.1 - 9.2e-19 67.9 0.1 1.7e-18 67.1 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 KFX89724.1 - 2.6e-07 30.5 0.2 4.8e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX89724.1 - 2.4e-05 24.3 0.3 4.4e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KFX89724.1 - 0.00012 21.8 11.5 0.00012 21.8 8.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) SDH_alpha PF03313.10 KFX89724.1 - 0.32 9.9 3.8 0.46 9.4 2.6 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Atg14 PF10186.4 KFX89724.1 - 1.1 8.1 7.4 1.8 7.4 5.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HET PF06985.6 KFX89726.1 - 2.6e-20 73.0 4.3 3.9e-17 62.7 0.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 KFX89726.1 - 3e-05 23.4 10.0 5.3e-05 22.6 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type WD40 PF00400.27 KFX89734.1 - 2.6e-30 103.1 8.9 2.9e-07 30.1 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX89734.1 - 9.3e-06 25.4 0.1 0.028 14.1 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KFX89734.1 - 0.0087 15.7 2.4 2.5 7.8 0.1 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KFX89734.1 - 0.012 14.1 0.0 14 4.0 0.0 3.3 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SNF2_N PF00176.18 KFX89737.1 - 5.1e-66 222.4 0.0 6.7e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFX89737.1 - 3.7e-08 33.4 0.0 1.3e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX89737.1 - 5e-07 29.3 0.0 9.9e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KFX89737.1 - 0.0012 17.6 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KFX89737.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ycf1 PF05758.7 KFX89738.1 - 3 5.4 8.1 3.9 5.0 5.6 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KFX89738.1 - 6.2 4.7 13.1 8.5 4.2 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein IMD PF08397.6 KFX89745.1 - 0.0012 18.2 2.6 0.011 15.0 1.8 2.0 1 1 0 1 1 1 1 IRSp53/MIM homology domain Arfaptin PF06456.8 KFX89745.1 - 0.0022 17.3 0.2 0.005 16.2 0.1 1.5 1 0 0 1 1 1 1 Arfaptin-like domain Seryl_tRNA_N PF02403.17 KFX89745.1 - 0.15 12.0 0.8 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TRI12 PF06609.8 KFX89746.1 - 2.3e-41 141.7 30.2 2.8e-41 141.4 20.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX89746.1 - 3.6e-21 75.2 60.5 3.6e-21 75.2 41.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89746.1 - 4e-10 38.8 39.3 2.5e-09 36.2 9.0 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter FAD_binding_3 PF01494.14 KFX89757.1 - 7e-08 31.8 0.0 8.7e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KFX89757.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.3 1 1 0 1 1 1 1 Squalene epoxidase PGA2 PF07543.7 KFX89764.1 - 3e-34 117.8 3.0 3.8e-34 117.4 2.1 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 Thymidylat_synt PF00303.14 KFX89766.1 - 2.6e-114 380.8 0.0 3e-114 380.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase EAP30 PF04157.11 KFX89769.1 - 8.4e-55 185.3 0.0 1.1e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KFX89769.1 - 2.3e-29 101.0 0.0 3.7e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 KFX89769.1 - 0.00022 20.7 5.4 0.0017 17.8 0.4 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.15 KFX89769.1 - 0.0028 17.1 0.0 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 KFX89769.1 - 0.065 12.3 13.2 0.11 11.6 0.7 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.2 KFX89769.1 - 0.1 12.4 0.3 0.1 12.4 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.11 KFX89770.1 - 4e-65 219.2 0.3 5.2e-65 218.8 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Fungal_trans PF04082.13 KFX89771.1 - 4.4e-11 42.1 0.0 9.6e-11 41.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX89771.1 - 2.6e-09 36.8 9.2 4.2e-05 23.6 1.4 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX89771.1 - 3.6e-09 36.3 8.4 0.00014 21.9 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX89771.1 - 7.7e-09 35.4 11.1 3.9e-06 26.8 2.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFX89771.1 - 4.3e-08 32.7 6.2 0.0031 17.3 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFX89771.1 - 5.8e-05 23.1 4.6 0.0083 16.3 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX89771.1 - 0.00059 19.9 4.9 0.061 13.4 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding LIM PF00412.17 KFX89771.1 - 0.23 11.5 5.3 1.9 8.6 0.6 2.5 1 1 1 2 2 2 0 LIM domain RRN7 PF11781.3 KFX89771.1 - 1.4 8.4 6.3 1.6 8.3 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Methyltransf_25 PF13649.1 KFX89772.1 - 1.2e-10 41.5 0.2 2.1e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89772.1 - 1.7e-07 30.9 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX89772.1 - 2e-07 31.4 0.0 4.8e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX89772.1 - 4.5e-05 23.2 0.0 0.0001 22.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89772.1 - 6.1e-05 23.4 0.0 0.00017 22.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89772.1 - 0.00019 21.9 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX89772.1 - 0.024 14.6 0.0 0.062 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KFX89772.1 - 0.029 13.7 0.1 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KFX89772.1 - 0.083 12.5 0.1 0.42 10.2 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Dala_Dala_lig_C PF07478.8 KFX89772.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus YscJ_FliF PF01514.12 KFX89777.1 - 0.0036 16.5 0.1 0.0048 16.0 0.0 1.1 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family GATA PF00320.22 KFX89780.1 - 1e-10 40.7 6.1 2.3e-10 39.6 4.2 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 KFX89780.1 - 0.078 12.9 2.5 0.17 11.9 1.8 1.6 1 0 0 1 1 1 0 zinc-finger eIF-5a PF01287.15 KFX89783.1 - 3.3e-13 49.3 0.3 4.6e-13 48.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 KFX89783.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Aminotran_1_2 PF00155.16 KFX89786.1 - 5.1e-13 48.6 0.0 6.8e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFX89786.1 - 0.0033 16.0 0.0 0.0072 14.9 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF3661 PF12400.3 KFX89787.1 - 6.1e-42 142.7 3.9 8.9e-42 142.2 2.7 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Polysacc_synt PF01943.12 KFX89787.1 - 1.2 8.3 8.3 1.5 8.0 1.5 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein RRM_1 PF00076.17 KFX89788.1 - 1e-18 66.6 1.3 1.3e-18 66.4 0.2 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX89788.1 - 8e-14 51.3 0.1 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX89788.1 - 4.1e-09 36.1 0.1 7.7e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTR2 PF00854.16 KFX89791.1 - 2.2e-26 92.5 1.5 2.2e-26 92.5 1.0 2.3 2 1 0 2 2 2 1 POT family TIR_2 PF13676.1 KFX89802.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 TIR domain HC2 PF07382.6 KFX89810.1 - 0.091 12.6 20.7 0.15 11.9 14.3 1.3 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Spc7 PF08317.6 KFX89810.1 - 1.1 7.7 11.8 1.8 7.1 7.5 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3138 PF11336.3 KFX89810.1 - 2.9 5.9 8.0 4.1 5.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Atg14 PF10186.4 KFX89810.1 - 5.4 5.8 7.9 12 4.7 5.5 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL25 PF01499.11 KFX89810.1 - 5.6 5.1 10.5 9.3 4.4 7.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Mnd1 PF03962.10 KFX89810.1 - 6.5 6.3 12.1 13 5.3 8.4 1.5 1 0 0 1 1 1 0 Mnd1 family Phage_Mu_Gam PF07352.7 KFX89810.1 - 8.4 5.8 17.7 1.7e+02 1.6 12.3 2.4 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Glyco_hydro_62 PF03664.8 KFX89811.1 - 8e-151 500.6 14.8 1e-150 500.3 10.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 KFX89811.1 - 2.1e-10 40.0 17.0 2.1e-10 40.0 11.8 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Kelch_5 PF13854.1 KFX89812.1 - 6.7e-07 29.1 3.6 2.2e-06 27.4 0.0 3.2 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.5 KFX89812.1 - 0.0023 17.1 0.6 0.0055 15.9 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 KFX89812.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain RRM_1 PF00076.17 KFX89813.1 - 1.1e-41 140.3 0.0 6.7e-21 73.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX89813.1 - 1.1e-32 111.7 0.0 6e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX89813.1 - 8.4e-21 73.5 0.0 1.1e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX89813.1 - 0.0018 17.9 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 KFX89813.1 - 0.045 12.2 34.6 0.05 12.0 24.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribosomal_L37 PF08561.5 KFX89814.1 - 1.6e-26 91.7 1.4 2.7e-19 68.5 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 KFX89814.1 - 0.05 13.7 0.1 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 TAFII55_N PF04658.8 KFX89815.1 - 1.9e-50 170.5 0.0 3.2e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region YgaB PF14182.1 KFX89815.1 - 0.025 14.8 0.2 0.07 13.3 0.1 1.8 1 1 0 1 1 1 0 YgaB-like protein CTD PF12815.2 KFX89815.1 - 0.4 11.1 7.7 8.6 6.8 4.2 2.3 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Alg6_Alg8 PF03155.10 KFX89816.1 - 1.5e-134 449.4 29.4 2e-83 280.8 8.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family 2-Hacid_dh_C PF02826.14 KFX89818.1 - 1.4e-52 177.4 0.0 2.4e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX89818.1 - 1.5e-34 118.3 0.3 2.1e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 KFX89818.1 - 0.00068 19.0 0.3 0.0032 16.9 0.0 2.3 2 0 0 2 2 2 1 ACT domain AlaDh_PNT_C PF01262.16 KFX89818.1 - 0.0038 16.8 1.8 0.03 13.9 0.4 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 KFX89818.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Lipase_GDSL_2 PF13472.1 KFX89819.1 - 2.1e-15 57.3 0.4 2.9e-15 56.8 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX89819.1 - 1.1e-11 44.9 0.0 1.9e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFX89819.1 - 0.00022 20.9 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SH3_1 PF00018.23 KFX89820.1 - 1e-39 133.6 7.5 6.3e-14 51.0 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KFX89820.1 - 2.1e-36 123.4 0.1 4.6e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KFX89820.1 - 4.3e-35 119.0 6.3 1.2e-13 50.3 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.12 KFX89820.1 - 1e-26 92.1 0.4 1.9e-08 33.6 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 KFX89820.1 - 2.7e-07 30.6 3.4 0.015 15.4 0.2 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain TPR_11 PF13414.1 KFX89821.1 - 4.2e-22 77.5 8.6 2.1e-09 36.8 0.7 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFX89821.1 - 1.7e-21 74.8 1.7 2.2e-05 23.8 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFX89821.1 - 3.8e-19 66.9 6.4 7e-05 22.4 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX89821.1 - 5.8e-16 57.5 7.4 0.00033 21.0 0.4 6.6 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFX89821.1 - 2.1e-14 53.1 8.3 1.9e-08 34.1 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX89821.1 - 3.1e-13 50.0 6.7 0.0003 21.3 0.3 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFX89821.1 - 1.1e-12 48.0 6.9 0.0065 16.7 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX89821.1 - 5.3e-11 41.4 0.3 0.0036 16.9 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX89821.1 - 1.8e-10 40.1 1.4 0.46 10.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX89821.1 - 2e-09 36.5 8.1 0.0033 17.0 0.1 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFX89821.1 - 9.8e-08 32.0 5.8 0.0036 17.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX89821.1 - 3.3e-07 30.3 1.2 2.9e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFX89821.1 - 4.2e-06 26.5 6.7 0.0049 16.6 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat CRISPR_Cse2 PF09485.5 KFX89821.1 - 0.00025 21.1 0.8 0.0018 18.3 0.1 2.4 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_10 PF13374.1 KFX89821.1 - 0.0027 17.5 5.2 0.15 12.0 0.3 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFX89821.1 - 0.0049 16.6 0.0 7.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFX89821.1 - 0.016 14.2 1.5 3.4 6.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX89821.1 - 0.017 15.5 10.2 18 6.0 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KFX89821.1 - 0.077 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit ODC_AZ PF02100.12 KFX89829.1 - 5.9e-28 96.5 0.0 9.8e-28 95.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TFIIIC_sub6 PF10419.4 KFX89830.1 - 9.1e-13 47.4 0.0 7.9e-12 44.4 0.0 2.3 2 0 0 2 2 2 1 TFIIIC subunit DUF4653 PF15546.1 KFX89830.1 - 0.041 13.1 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) WTX PF09422.5 KFX89831.1 - 0.0016 17.5 2.1 0.0016 17.5 1.5 1.4 2 0 0 2 2 2 1 WTX protein Alk_phosphatase PF00245.15 KFX89833.1 - 1e-64 218.7 0.1 2.2e-64 217.7 0.1 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 KFX89833.1 - 1.9e-06 27.4 0.3 3.5e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SKG6 PF08693.5 KFX89833.1 - 3.8e-06 26.0 0.8 1.4e-05 24.3 0.6 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sulfatase PF00884.18 KFX89833.1 - 1e-05 24.9 0.2 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KFX89833.1 - 0.0026 16.2 0.2 0.0026 16.2 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4448 PF14610.1 KFX89833.1 - 0.0065 15.9 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF1501 PF07394.7 KFX89833.1 - 0.12 11.1 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Band_7 PF01145.20 KFX89835.1 - 0.094 12.6 0.1 7.8 6.3 0.0 2.1 2 0 0 2 2 2 0 SPFH domain / Band 7 family Peptidase_S64 PF08192.6 KFX89836.1 - 0.0096 14.3 0.2 0.02 13.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S64 Ecm33 PF12454.3 KFX89844.1 - 1.9e-09 37.2 0.3 6.8e-09 35.4 0.2 2.1 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 KFX89844.1 - 1.2e-06 28.4 1.7 0.24 11.3 0.0 4.4 1 1 3 4 4 4 2 Receptor L domain LRR_5 PF13306.1 KFX89844.1 - 0.0063 16.2 1.6 2.9 7.5 0.4 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) UCR_14kD PF02271.11 KFX89847.1 - 1.3e-45 153.4 0.0 1.5e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DSPc PF00782.15 KFX89851.1 - 3e-19 68.9 0.0 3.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX89851.1 - 0.00041 19.7 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFX89851.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 2 0 0 2 2 2 0 Tyrosine phosphatase family Rb_C PF08934.5 KFX89851.1 - 0.075 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Rb C-terminal domain Init_tRNA_PT PF04179.7 KFX89851.1 - 0.091 11.6 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase WD40 PF00400.27 KFX89871.1 - 1.5e-23 81.7 18.9 3.5e-06 26.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX89871.1 - 1.9e-06 27.7 0.1 0.00052 19.7 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 KFX89871.1 - 0.022 14.4 4.4 0.27 10.9 0.3 3.6 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Methyltransf_23 PF13489.1 KFX89872.1 - 1.8e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89872.1 - 1.5e-08 34.4 0.0 1e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89872.1 - 4e-07 30.6 0.0 2.8e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX89872.1 - 5.7e-06 26.7 0.0 1.4e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89872.1 - 0.00014 22.2 0.0 0.00048 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX89872.1 - 0.0004 19.8 0.0 0.00069 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KFX89872.1 - 0.0035 16.8 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 KFX89872.1 - 0.0048 16.1 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KFX89872.1 - 0.0053 15.8 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KFX89872.1 - 0.02 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KFX89872.1 - 0.031 13.4 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KFX89872.1 - 0.046 12.8 0.0 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF1156 PF06634.7 KFX89872.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Methyltransf_25 PF13649.1 KFX89872.1 - 0.1 12.9 0.0 0.76 10.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain DIOX_N PF14226.1 KFX89877.1 - 2.5e-23 82.7 0.0 6e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.27 KFX89877.1 - 2.6e-07 30.2 7.5 0.0024 17.6 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 KFX89878.1 - 1e-31 108.7 0.6 1.2e-31 108.5 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KFX89878.1 - 0.022 14.8 0.2 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Pkinase PF00069.20 KFX89881.1 - 2.4e-59 200.6 0.0 3.7e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89881.1 - 4.9e-27 94.6 0.0 6.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX89881.1 - 0.002 17.1 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFX89881.1 - 0.16 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.16 KFX89882.1 - 0.0001 22.1 7.8 0.0001 22.1 5.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFX89882.1 - 0.19 11.6 8.8 0.36 10.6 6.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Na_H_Exchanger PF00999.16 KFX89889.1 - 3.1e-42 144.4 7.2 4.2e-42 144.0 5.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Filament PF00038.16 KFX89889.1 - 0.022 14.2 2.7 0.032 13.6 1.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein AdoMet_MTase PF07757.8 KFX89889.1 - 0.093 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF1694 PF07997.6 KFX89889.1 - 0.13 12.1 0.0 3.2 7.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1694) TrkH PF02386.11 KFX89890.1 - 4.3e-115 384.0 17.6 1.1e-114 382.7 6.6 2.1 2 0 0 2 2 2 2 Cation transport protein PHO4 PF01384.15 KFX89892.1 - 3e-110 367.9 14.0 4.1e-110 367.4 9.7 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF1290 PF06947.7 KFX89892.1 - 0.79 9.6 4.2 0.51 10.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) DUF3435 PF11917.3 KFX89893.1 - 0.0043 15.8 0.0 0.0059 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) E1-E2_ATPase PF00122.15 KFX89894.1 - 2.3e-64 216.5 3.3 3.8e-64 215.8 2.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX89894.1 - 3.4e-32 111.4 10.8 3.4e-32 111.4 7.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX89894.1 - 3.2e-28 99.6 0.0 9.6e-27 94.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX89894.1 - 9.1e-17 60.8 0.0 4e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFX89894.1 - 2.1e-12 47.6 0.0 5.3e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX89894.1 - 7.3e-08 31.7 0.0 2.2e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFX89894.1 - 0.00053 19.6 0.8 0.00099 18.7 0.4 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Herpes_UL14 PF03580.9 KFX89898.1 - 0.12 12.1 1.8 0.15 11.8 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Copper-fist PF00649.13 KFX89913.1 - 1.2e-18 66.0 1.4 2.6e-18 64.9 1.0 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain Bac_rhamnosid PF05592.6 KFX89916.1 - 8e-186 618.1 0.0 9.7e-186 617.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KFX89916.1 - 1.6e-54 184.0 0.0 3e-54 183.1 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain 1-cysPrx_C PF10417.4 KFX89917.1 - 0.14 11.8 1.5 0.26 10.9 1.0 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Sugar_tr PF00083.19 KFX89920.1 - 2.1e-80 270.5 21.3 2.6e-80 270.2 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89920.1 - 3.4e-31 108.2 25.8 3.4e-31 108.2 17.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX89920.1 - 0.00018 19.8 3.1 0.00028 19.2 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KFX89920.1 - 0.0092 14.1 2.1 0.015 13.4 1.5 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector AAA_5 PF07728.9 KFX89921.1 - 3.7e-124 409.0 0.0 5.8e-21 74.6 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFX89921.1 - 2.4e-29 102.5 0.0 0.00013 22.7 0.0 8.0 6 1 0 6 6 6 5 AAA domain AAA_33 PF13671.1 KFX89921.1 - 2.8e-28 98.6 0.0 0.00099 19.0 0.0 7.5 6 1 0 6 6 6 6 AAA domain AAA_3 PF07726.6 KFX89921.1 - 5.4e-28 97.2 0.0 7.7e-11 41.7 0.0 8.0 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KFX89921.1 - 4.5e-27 94.8 0.0 0.00037 20.6 0.0 7.4 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX89921.1 - 5.5e-26 91.7 16.5 0.00028 20.9 0.1 8.8 8 0 0 8 8 6 5 AAA ATPase domain AAA_22 PF13401.1 KFX89921.1 - 4.3e-25 88.3 1.0 0.0079 16.3 0.0 8.6 8 1 0 8 8 7 6 AAA domain AAA_14 PF13173.1 KFX89921.1 - 8e-21 74.2 0.0 0.0014 18.5 0.0 7.8 7 0 0 7 7 7 3 AAA domain AAA_18 PF13238.1 KFX89921.1 - 4.3e-20 72.3 0.1 0.0037 17.5 0.0 7.3 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 KFX89921.1 - 1.4e-19 70.5 0.4 0.00041 20.4 0.0 8.0 7 0 0 7 7 7 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 KFX89921.1 - 3.4e-19 68.9 0.4 0.027 13.9 0.0 6.8 6 0 0 6 6 6 5 Sigma-54 interaction domain ABC_tran PF00005.22 KFX89921.1 - 1.6e-17 64.0 1.5 0.0086 16.3 0.0 7.5 7 0 0 7 7 6 3 ABC transporter DUF258 PF03193.11 KFX89921.1 - 2.1e-16 59.5 0.7 0.017 14.3 0.0 6.1 6 0 0 6 6 6 4 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KFX89921.1 - 4e-15 55.8 4.0 0.094 12.8 0.0 7.5 7 0 0 7 7 7 3 RNA helicase NACHT PF05729.7 KFX89921.1 - 2.1e-14 53.5 4.8 0.16 11.6 0.0 6.2 5 0 0 5 5 5 4 NACHT domain UPF0079 PF02367.12 KFX89921.1 - 2.3e-14 53.0 3.8 0.1 12.2 0.0 6.4 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KFX89921.1 - 1.1e-13 51.1 0.6 0.9 9.2 0.0 6.7 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KFX89921.1 - 1.7e-13 50.1 5.2 0.0052 16.5 0.1 6.7 6 0 0 6 6 6 3 Part of AAA domain T2SE PF00437.15 KFX89921.1 - 3.6e-13 49.0 0.5 0.068 12.0 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein Arch_ATPase PF01637.13 KFX89921.1 - 5.5e-13 49.1 0.0 0.021 14.5 0.0 6.7 6 0 0 6 6 6 1 Archaeal ATPase Zeta_toxin PF06414.7 KFX89921.1 - 5.8e-13 48.3 4.7 0.58 9.2 0.0 7.2 7 0 0 7 7 7 3 Zeta toxin AAA_29 PF13555.1 KFX89921.1 - 2e-12 46.4 0.2 0.13 11.7 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain Miro PF08477.8 KFX89921.1 - 2.5e-12 47.3 1.7 3.5 8.1 0.0 6.9 6 0 0 6 6 6 0 Miro-like protein AAA_25 PF13481.1 KFX89921.1 - 1.1e-11 44.5 0.4 0.47 9.8 0.0 5.9 5 0 0 5 5 5 4 AAA domain AAA_28 PF13521.1 KFX89921.1 - 2.2e-11 43.9 5.5 0.11 12.4 0.0 7.7 7 0 0 7 7 7 1 AAA domain IstB_IS21 PF01695.12 KFX89921.1 - 8.5e-10 38.3 0.2 0.3 10.4 0.0 5.8 6 0 0 6 6 6 2 IstB-like ATP binding protein RuvB_N PF05496.7 KFX89921.1 - 6.5e-09 35.1 4.6 0.037 13.0 0.0 6.5 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 KFX89921.1 - 2.1e-08 33.7 3.6 0.022 14.2 0.0 5.8 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KFX89921.1 - 2.8e-08 33.4 4.1 0.68 9.3 0.0 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KFX89921.1 - 5.6e-08 32.7 0.8 4.6 7.2 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 KFX89921.1 - 1.7e-07 30.9 0.1 1.1 8.7 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KFX89921.1 - 2.3e-07 29.8 0.3 0.97 8.0 0.0 5.6 6 0 0 6 6 6 2 Rad17 cell cycle checkpoint protein Thymidylate_kin PF02223.12 KFX89921.1 - 3.1e-07 29.9 0.2 4.8 6.5 0.0 5.9 5 0 0 5 5 5 0 Thymidylate kinase AAA_24 PF13479.1 KFX89921.1 - 7.9e-07 28.8 0.0 3.9 6.9 0.0 6.0 6 0 0 6 6 6 0 AAA domain FtsK_SpoIIIE PF01580.13 KFX89921.1 - 1.8e-06 27.6 3.1 3.9 6.8 0.0 5.6 5 0 0 5 5 5 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 KFX89921.1 - 2.3e-06 27.4 6.7 0.97 9.1 0.1 6.0 6 0 0 6 6 5 2 NTPase cobW PF02492.14 KFX89921.1 - 3.1e-06 26.7 3.2 4.9 6.5 0.0 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 KFX89921.1 - 1e-05 25.2 0.0 0.22 11.0 0.0 6.1 6 0 0 6 6 6 1 AAA domain AAA_7 PF12775.2 KFX89921.1 - 2.3e-05 23.6 1.5 0.84 8.6 0.0 4.7 5 0 0 5 5 4 1 P-loop containing dynein motor region D3 TIP49 PF06068.8 KFX89921.1 - 0.00021 20.1 3.8 0.56 8.8 0.0 4.8 6 0 0 6 6 5 1 TIP49 C-terminus KaiC PF06745.8 KFX89921.1 - 0.00028 20.0 0.4 9.2 5.3 0.0 4.5 4 0 0 4 4 4 0 KaiC ATP-synt_ab PF00006.20 KFX89921.1 - 0.00034 20.1 0.0 17 4.8 0.0 5.1 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 KFX89921.1 - 0.00042 19.9 0.5 2.4 7.6 0.0 5.3 6 0 0 6 6 5 1 Phosphoribulokinase / Uridine kinase family AAA_6 PF12774.2 KFX89921.1 - 0.0012 18.4 0.1 6.6 6.1 0.0 6.0 8 1 0 8 8 7 0 Hydrolytic ATP binding site of dynein motor region D1 PhoH PF02562.11 KFX89921.1 - 0.0017 17.6 1.1 6.2 5.9 0.0 4.8 5 0 0 5 5 5 0 PhoH-like protein ATP_bind_1 PF03029.12 KFX89921.1 - 0.0074 15.8 7.1 7 6.1 0.1 5.5 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein VirE PF05272.6 KFX89921.1 - 0.0095 15.4 0.0 2.1 7.7 0.0 3.9 5 0 0 5 5 4 1 Virulence-associated protein E NB-ARC PF00931.17 KFX89921.1 - 0.02 13.7 6.2 15 4.3 0.1 5.2 6 0 0 6 6 6 0 NB-ARC domain CbiA PF01656.18 KFX89921.1 - 0.039 13.3 3.0 9.5 5.5 0.1 4.3 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ras PF00071.17 KFX89921.1 - 0.045 13.1 1.7 36 3.7 0.0 4.6 5 0 0 5 5 5 0 Ras family tRNA_lig_kinase PF08303.6 KFX89921.1 - 0.05 13.4 0.1 0.29 10.9 0.0 2.4 2 0 0 2 2 1 0 tRNA ligase kinase domain AAA_15 PF13175.1 KFX89921.1 - 0.092 11.7 0.0 13 4.6 0.0 4.0 5 0 0 5 5 5 0 AAA ATPase domain Dynamin_N PF00350.18 KFX89921.1 - 0.17 11.6 3.4 7.3 6.3 0.0 4.5 4 0 0 4 4 4 0 Dynamin family APS_kinase PF01583.15 KFX89921.1 - 0.34 10.5 2.2 9.4 5.8 0.0 4.2 5 0 0 5 5 4 0 Adenylylsulphate kinase AAA_23 PF13476.1 KFX89921.1 - 2.3 8.5 0.0 2.3 8.5 0.0 9.3 8 2 0 8 8 7 0 AAA domain Ribosomal_L12 PF00542.14 KFX89922.1 - 1.9e-17 63.0 3.2 6.2e-17 61.3 1.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 KFX89922.1 - 0.021 14.9 0.8 3.3 7.9 0.0 2.7 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain HrpB4 PF09502.5 KFX89922.1 - 0.15 11.2 1.8 0.23 10.6 0.3 1.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB4) NAD_binding_1 PF00175.16 KFX89923.1 - 9.7e-26 90.4 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFX89923.1 - 2.3e-24 85.4 0.0 4.7e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFX89923.1 - 0.00041 20.2 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CFEM PF05730.6 KFX89924.1 - 7.5e-06 25.6 4.7 1.1e-05 25.2 3.2 1.2 1 0 0 1 1 1 1 CFEM domain Epimerase PF01370.16 KFX89925.1 - 1.1e-08 34.8 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX89925.1 - 4.8e-05 23.4 0.0 8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX89925.1 - 0.0027 16.4 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX89925.1 - 0.0092 14.9 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KFX89925.1 - 0.017 15.4 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KFX89925.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KFX89925.1 - 0.047 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase POTRA_1 PF08478.5 KFX89925.1 - 0.11 12.5 0.1 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 POTRA domain, FtsQ-type MARVEL PF01284.18 KFX89926.1 - 8.8e-07 28.8 2.6 8.8e-07 28.8 1.8 2.1 2 0 0 2 2 2 1 Membrane-associating domain Ion_trans PF00520.26 KFX89926.1 - 0.065 12.4 1.9 0.086 12.0 1.3 1.3 1 0 0 1 1 1 0 Ion transport protein Neurochondrin PF05536.6 KFX89927.1 - 3.5e-78 263.2 0.0 4.5e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin Voltage_CLC PF00654.15 KFX89928.1 - 6.2e-87 291.9 38.0 6.2e-87 291.9 26.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFX89928.1 - 1.7e-08 34.0 0.0 0.0002 21.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain Mito_carr PF00153.22 KFX89929.1 - 6e-48 160.5 5.6 9.8e-19 66.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DJ-1_PfpI PF01965.19 KFX89930.1 - 6.7e-21 74.2 0.0 1e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KFX89930.1 - 5.1e-06 25.9 0.4 1.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family MFS_1 PF07690.11 KFX89931.1 - 9.6e-44 149.5 64.1 8.7e-37 126.6 16.7 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX89931.1 - 6.4e-16 57.6 13.9 8.8e-16 57.2 9.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX89931.1 - 2.9e-14 52.5 15.5 2.9e-14 52.5 10.7 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter Trypan_PARP PF05887.6 KFX89931.1 - 0.3 10.9 3.8 0.51 10.1 2.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Gelsolin PF00626.17 KFX89932.1 - 1.8e-37 126.8 0.0 9e-13 47.7 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Hemerythrin PF01814.18 KFX89933.1 - 1.6e-05 25.0 0.0 2.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sec8_exocyst PF04048.9 KFX89933.1 - 0.17 11.5 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain His_Phos_1 PF00300.17 KFX89934.1 - 3.7e-16 59.6 0.0 5.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RAP1 PF07218.6 KFX89934.1 - 1 7.3 7.8 1.7 6.6 5.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NmrA PF05368.8 KFX89936.1 - 4.6e-15 55.4 0.0 2.3e-14 53.1 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX89936.1 - 3.2e-12 46.8 0.0 4.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX89936.1 - 0.0029 17.0 0.1 0.015 14.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.18 KFX89937.1 - 1.2e-25 89.6 1.0 2.2e-25 88.7 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX89937.1 - 0.0011 18.8 1.0 0.0045 16.8 0.7 2.1 1 0 0 1 1 1 1 Berberine and berberine like DUF423 PF04241.10 KFX89938.1 - 0.0068 16.3 0.9 0.0068 16.3 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF423) AMP-binding PF00501.23 KFX89939.1 - 7.3e-83 278.2 0.0 8.9e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GCS PF03074.11 KFX89942.1 - 1.6e-36 126.1 0.1 2e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase bZIP_Maf PF03131.12 KFX89949.1 - 9.5e-07 29.0 12.0 9.5e-07 29.0 8.3 1.8 1 1 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFX89949.1 - 1.6e-06 27.9 10.0 1.6e-06 27.9 7.0 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFX89949.1 - 7.4e-06 25.6 9.1 7.4e-06 25.6 6.3 2.0 3 0 0 3 3 3 1 Basic region leucine zipper Skp1 PF01466.14 KFX89950.1 - 4.7e-39 132.2 1.0 7.1e-39 131.6 0.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFX89950.1 - 1.9e-20 72.7 0.1 4.1e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KFX89950.1 - 0.056 13.4 1.5 0.057 13.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) ABC_membrane PF00664.18 KFX89951.1 - 9.1e-96 320.4 39.5 4e-49 167.4 10.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX89951.1 - 3.5e-66 221.6 0.3 1.9e-31 109.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KFX89951.1 - 4e-12 45.8 0.0 0.00087 18.5 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX89951.1 - 1.3e-09 38.4 0.3 0.2 11.6 0.0 4.3 2 2 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KFX89951.1 - 3.3e-08 32.9 1.9 0.00058 19.3 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX89951.1 - 6.8e-08 32.7 0.2 0.0018 18.2 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KFX89951.1 - 9.6e-07 29.6 0.2 0.13 13.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain ABC_ATPase PF09818.4 KFX89951.1 - 2.1e-06 26.6 1.8 0.02 13.5 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KFX89951.1 - 5.3e-06 25.7 0.0 0.22 10.7 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX89951.1 - 1.2e-05 24.7 0.4 0.26 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFX89951.1 - 0.00023 21.2 0.7 2.9 8.0 0.0 4.4 4 1 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 KFX89951.1 - 0.00096 19.0 2.7 1.1 9.2 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KFX89951.1 - 0.0027 17.6 0.4 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX89951.1 - 0.004 17.4 0.0 4.4 7.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX89951.1 - 0.0048 16.7 0.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KFX89951.1 - 0.0053 16.6 1.3 1.6 8.4 0.0 2.7 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KFX89951.1 - 0.0096 15.6 0.3 8.1 6.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX89951.1 - 0.03 14.2 0.0 7.5 6.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.8 KFX89951.1 - 0.042 12.7 0.1 3.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) G-alpha PF00503.15 KFX89951.1 - 0.045 12.4 0.0 5.5 5.5 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 KFX89951.1 - 0.12 11.7 4.6 19 4.5 0.0 3.9 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 KFX89951.1 - 0.13 12.3 0.0 18 5.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KFX89951.1 - 0.29 11.4 2.5 8.3 6.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain Cache_3 PF14827.1 KFX89951.1 - 1.7 8.6 6.2 15 5.5 0.1 3.4 3 0 0 3 3 3 0 Sensory domain of two-component sensor kinase WD40 PF00400.27 KFX89965.1 - 2.1e-16 59.1 10.7 1e-06 28.3 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 KFX89965.1 - 0.0042 16.3 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity PD40 PF07676.7 KFX89965.1 - 0.079 12.6 0.2 6.9 6.4 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RRM_5 PF13893.1 KFX89966.1 - 5.5e-10 38.9 0.0 8.2e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX89966.1 - 1.4e-08 34.2 0.0 3.6e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX89966.1 - 6.9e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFX89966.1 - 0.0021 17.6 0.8 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 Calcipressin Glyco_hydro_47 PF01532.15 KFX89967.1 - 7.1e-165 549.0 0.0 8.8e-165 548.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.11 KFX89968.1 - 0.44 9.2 17.6 0.044 12.4 7.1 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily FSH1 PF03959.8 KFX89969.1 - 5.6e-31 107.6 0.0 8.2e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFX89969.1 - 7.6e-05 22.6 1.3 0.00011 22.1 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX89969.1 - 9.1e-05 21.9 0.0 0.00077 18.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFX89969.1 - 0.00081 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 KFX89969.1 - 0.063 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.8 KFX89969.1 - 0.13 11.8 0.2 0.79 9.2 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold LacAB_rpiB PF02502.13 KFX89975.1 - 2.5e-42 143.8 0.0 2.9e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Glucokinase PF02685.11 KFX89975.1 - 0.099 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Glucokinase Glyco_hydro_43 PF04616.9 KFX89979.1 - 1.5e-63 214.5 2.8 1.9e-63 214.2 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TUG-UBL1 PF11470.3 KFX89979.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Beta-lactamase PF00144.19 KFX89980.1 - 2e-27 96.0 0.1 3.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Arginase PF00491.16 KFX89981.1 - 3.9e-83 278.9 0.5 4.9e-83 278.6 0.4 1.0 1 0 0 1 1 1 1 Arginase family FAD_binding_4 PF01565.18 KFX89982.1 - 2.3e-17 62.7 1.9 3.6e-17 62.1 0.6 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 KFX89982.1 - 2.2e-06 27.4 0.1 7.2e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like HeLo PF14479.1 KFX89984.1 - 1.3e-39 136.1 0.0 1.7e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF4218 PF13960.1 KFX89984.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HET-s_218-289 PF11558.3 KFX89984.1 - 0.015 15.2 0.3 0.057 13.4 0.1 2.1 2 1 0 2 2 2 0 Het-s 218-289 Mur_ligase_C PF02875.16 KFX89984.1 - 0.14 12.1 0.2 0.53 10.3 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain zf-C2H2_4 PF13894.1 KFX89985.1 - 0.0012 19.0 7.1 0.014 15.7 2.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger PRA1 PF03208.14 KFX89986.1 - 4.1 6.7 6.7 2.6 7.3 0.8 2.4 2 0 0 2 2 2 0 PRA1 family protein Pec_lyase_C PF00544.14 KFX89987.1 - 6.8e-27 94.2 2.0 1e-26 93.6 1.4 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFX89987.1 - 1.1e-07 31.6 9.1 1.3e-07 31.4 5.6 1.5 1 1 0 1 1 1 1 Right handed beta helix region Mito_carr PF00153.22 KFX89992.1 - 6.7e-31 105.8 9.4 3.5e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YtrH PF14034.1 KFX89992.1 - 0.1 12.5 1.7 0.22 11.4 0.1 2.3 3 0 0 3 3 3 0 Sporulation protein YtrH Ank_2 PF12796.2 KFX89999.1 - 1.1e-24 86.5 5.0 1.5e-08 34.8 0.2 4.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89999.1 - 4.4e-18 64.1 16.4 0.0054 16.4 0.1 8.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KFX89999.1 - 1.5e-17 63.2 12.2 5.1e-08 32.9 0.7 6.1 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX89999.1 - 2e-16 59.9 6.7 0.004 17.6 0.0 7.1 5 3 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX89999.1 - 2.3e-15 55.1 7.1 0.017 15.3 0.0 7.6 8 1 0 8 8 8 4 Ankyrin repeat adh_short PF00106.20 KFX90004.1 - 1.3e-28 100.0 0.2 1.6e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX90004.1 - 1.2e-20 74.3 0.1 1.5e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX90004.1 - 7.6e-13 48.5 0.0 1.1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX90004.1 - 3e-11 43.6 0.0 4.5e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX90004.1 - 2.8e-06 26.9 0.1 4.8e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX90004.1 - 6.8e-05 21.8 0.2 0.00013 20.9 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 KFX90004.1 - 6.8e-05 22.2 0.2 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 KFX90004.1 - 0.0013 18.4 0.3 0.0041 16.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KFX90004.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 KFX90004.1 - 0.0043 17.4 0.1 0.0096 16.3 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFX90004.1 - 0.024 14.3 0.2 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2703 PF10865.3 KFX90004.1 - 0.032 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) ADH_zinc_N PF00107.21 KFX90004.1 - 0.13 11.7 2.5 0.16 11.4 0.6 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 KFX90005.1 - 6e-35 120.5 51.1 6e-35 120.5 35.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX90005.1 - 8.6e-13 47.6 19.1 8.6e-13 47.6 13.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Lip_prot_lig_C PF10437.4 KFX90005.1 - 0.098 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Fungal_trans PF04082.13 KFX90006.1 - 2.5e-18 65.8 0.1 4.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90006.1 - 4.3e-10 39.3 8.0 8.5e-10 38.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX90007.1 - 2.1e-25 89.5 0.1 2.8e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX90007.1 - 1.6e-09 37.6 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX90007.1 - 2.6e-07 30.6 0.0 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFX90007.1 - 0.00049 19.8 1.4 0.0012 18.5 1.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFX90007.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX90007.1 - 0.043 12.6 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CS PF04969.11 KFX90008.1 - 1.4e-11 44.8 0.3 2.1e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 KFX90008.1 - 0.18 12.2 10.0 0.28 11.5 6.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Snf7 PF03357.16 KFX90009.1 - 4e-21 75.1 16.3 4e-21 75.1 11.3 2.3 2 0 0 2 2 2 1 Snf7 zf-CCCH PF00642.19 KFX90010.1 - 1.3e-06 27.8 10.5 3.9e-06 26.4 2.3 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 KFX90011.1 - 1.2e-16 60.0 0.0 2.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX90011.1 - 5.8e-13 48.6 0.0 9.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX90011.1 - 6.2e-07 29.1 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFX90011.1 - 4.4e-06 27.0 0.9 4.4e-06 27.0 0.7 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 CCER1 PF15482.1 KFX90011.1 - 0.09 12.4 2.6 0.92 9.0 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Shadoo PF14999.1 KFX90011.1 - 4.7 7.0 25.1 0.025 14.4 3.5 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective BNR PF02012.15 KFX90012.1 - 1.4e-16 57.5 20.4 0.11 12.3 0.0 9.5 8 0 0 8 8 8 7 BNR/Asp-box repeat CBM_1 PF00734.13 KFX90012.1 - 7.8e-11 41.4 10.3 2.5e-10 39.8 7.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain PSII_BNR PF14870.1 KFX90012.1 - 0.0047 15.9 17.5 0.83 8.5 0.1 6.5 5 2 0 5 5 5 3 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 KFX90012.1 - 0.01 15.4 0.2 5 6.7 0.0 4.1 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain Pollen_allerg_1 PF01357.16 KFX90012.1 - 0.041 13.6 0.1 23 4.8 0.0 3.2 2 1 1 3 3 3 0 Pollen allergen Fungal_trans PF04082.13 KFX90013.1 - 3e-33 114.7 0.4 1.4e-32 112.5 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90013.1 - 1.3e-08 34.6 15.2 2e-08 33.9 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KOW PF00467.24 KFX90014.1 - 1.6e-08 33.9 1.3 3.5e-08 32.8 0.6 1.8 2 0 0 2 2 2 1 KOW motif adh_short PF00106.20 KFX90015.1 - 4.5e-12 46.2 0.4 6.6e-12 45.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX90015.1 - 1.1e-07 31.9 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX90015.1 - 1.3e-05 24.9 0.0 5.2e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 KR domain PGM_PMM_III PF02880.11 KFX90015.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF883 PF05957.8 KFX90016.1 - 0.0032 17.8 0.8 0.0032 17.8 0.5 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Med9 PF07544.8 KFX90016.1 - 0.092 12.4 4.9 0.25 11.1 0.2 3.4 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Tup_N PF08581.5 KFX90016.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.0 1 1 2 3 3 3 0 Tup N-terminal BLOC1_2 PF10046.4 KFX90016.1 - 0.38 10.9 6.2 4.2 7.5 0.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4559 PF15112.1 KFX90016.1 - 1.2 8.2 6.3 0.32 10.1 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) IncA PF04156.9 KFX90016.1 - 8.5 5.9 9.1 14 5.2 4.5 2.4 1 1 1 2 2 2 0 IncA protein Lge1 PF11488.3 KFX90017.1 - 0.0099 16.0 1.7 0.022 14.9 0.2 2.4 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 NMD3 PF04981.8 KFX90017.1 - 0.086 11.9 2.3 0.15 11.1 1.6 1.2 1 0 0 1 1 1 0 NMD3 family CinA PF02464.12 KFX90019.1 - 5.5e-15 55.1 0.0 7.1e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein DUF155 PF02582.9 KFX90020.1 - 1.3e-58 197.7 0.1 1.9e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 cNMP_binding PF00027.24 KFX90026.1 - 7.2e-43 144.3 0.0 4.9e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 KFX90026.1 - 0.051 12.5 0.0 0.53 9.2 0.0 2.2 2 0 0 2 2 2 0 GXGXG motif p450 PF00067.17 KFX90029.1 - 1.9e-17 62.9 0.0 2.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 S-AdoMet_synt_C PF02773.11 KFX90031.1 - 3e-76 253.7 0.1 5.3e-76 252.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KFX90031.1 - 1.2e-47 160.8 0.0 2e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFX90031.1 - 3e-42 142.9 0.4 7.6e-42 141.5 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 KFX90032.1 - 1.2e-69 234.4 0.0 1.4e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KFX90032.1 - 4.4e-05 24.2 0.0 0.00011 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFX90032.1 - 0.00039 20.3 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFX90032.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFX90032.1 - 0.0031 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFX90032.1 - 0.0037 17.4 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 KFX90032.1 - 0.0045 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX90032.1 - 0.0092 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KFX90032.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX90032.1 - 0.015 15.0 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 KFX90032.1 - 0.015 14.7 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KFX90032.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KFX90032.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 KFX90032.1 - 0.025 14.0 0.0 2.3 7.6 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 KFX90032.1 - 0.025 14.1 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFX90032.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 KFX90032.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 KFX90032.1 - 0.037 12.9 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 KFX90032.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX90032.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KFX90032.1 - 0.064 12.2 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.9 KFX90032.1 - 0.065 12.2 0.0 0.065 12.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ArsA_ATPase PF02374.10 KFX90032.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase FtsK_SpoIIIE PF01580.13 KFX90032.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KFX90032.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFX90032.1 - 0.13 11.9 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KFX90032.1 - 0.14 11.6 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KFX90032.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 KFX90032.1 - 0.15 11.1 0.1 0.42 9.7 0.0 1.9 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KFX90032.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ank_2 PF12796.2 KFX90033.1 - 7e-84 276.2 16.6 6.8e-20 71.1 0.1 7.2 3 3 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90033.1 - 1.2e-50 166.8 25.0 1.7e-10 40.1 0.0 14.7 15 1 0 15 15 15 10 Ankyrin repeat Ank_4 PF13637.1 KFX90033.1 - 6.4e-46 153.9 7.5 7e-11 42.3 0.1 9.6 8 2 3 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX90033.1 - 1.1e-43 146.2 13.9 1.4e-13 50.5 0.0 11.0 4 3 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX90033.1 - 2.1e-36 120.3 3.9 2.2e-08 33.5 0.0 12.4 12 1 1 13 13 13 7 Ankyrin repeat Nif11 PF07862.6 KFX90033.1 - 0.00071 19.4 4.4 0.54 10.2 0.2 5.2 5 1 1 6 6 6 1 Nitrogen fixation protein of unknown function RTA1 PF04479.8 KFX90034.1 - 1.7e-58 197.7 9.5 1.7e-58 197.7 6.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.3 KFX90035.1 - 4.2e-07 28.9 3.1 6e-07 28.3 0.2 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain SNF2_N PF00176.18 KFX90036.1 - 1.1e-63 214.8 0.0 1.7e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFX90036.1 - 1.5e-23 82.2 2.0 1.1e-12 47.3 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFX90036.1 - 1.2e-13 50.7 0.0 3.3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KFX90036.1 - 3e-10 40.2 0.0 1.6e-09 37.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) ABC_tran PF00005.22 KFX90037.1 - 3e-33 115.0 0.0 4.6e-15 56.1 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 KFX90037.1 - 4.5e-14 51.7 5.2 4.5e-14 51.7 3.6 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KFX90037.1 - 3.7e-13 50.0 7.1 0.013 15.4 0.1 4.7 3 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFX90037.1 - 3.4e-11 42.8 1.8 0.0014 17.8 0.0 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFX90037.1 - 8.8e-07 28.3 0.1 2.3 7.1 0.0 4.4 4 1 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 KFX90037.1 - 4.6e-06 27.4 0.0 0.2 12.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KFX90037.1 - 4.6e-05 23.6 0.1 0.04 14.1 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.22 KFX90037.1 - 5.6e-05 22.5 3.2 5.6e-05 22.5 2.2 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_29 PF13555.1 KFX90037.1 - 7e-05 22.2 0.1 0.065 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX90037.1 - 8.7e-05 22.6 0.0 0.023 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX90037.1 - 0.00015 22.0 0.1 0.35 11.1 0.0 3.0 4 0 0 4 4 2 1 AAA domain DUF258 PF03193.11 KFX90037.1 - 0.00027 20.1 2.7 0.55 9.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX90037.1 - 0.00048 20.5 0.1 0.035 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 KFX90037.1 - 0.00093 18.7 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Fer4_21 PF14697.1 KFX90037.1 - 0.00096 18.9 11.8 0.0022 17.8 8.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 KFX90037.1 - 0.00099 18.5 0.1 0.63 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFX90037.1 - 0.002 18.6 0.2 0.21 12.0 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein UPF0079 PF02367.12 KFX90037.1 - 0.002 17.7 0.2 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KFX90037.1 - 0.002 17.8 1.8 0.2 11.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFX90037.1 - 0.0021 18.2 1.0 0.56 10.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 KFX90037.1 - 0.0026 17.6 0.3 0.13 12.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 KFX90037.1 - 0.003 17.3 11.8 0.0068 16.2 1.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.7 KFX90037.1 - 0.0036 16.9 2.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.10 KFX90037.1 - 0.0068 15.1 0.1 0.068 11.8 0.0 2.3 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 KFX90037.1 - 0.011 14.2 0.0 0.011 14.2 0.0 2.0 3 0 0 3 3 1 0 AAA domain Thymidylate_kin PF02223.12 KFX90037.1 - 0.011 15.0 2.4 7.7 5.8 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase SRP54 PF00448.17 KFX90037.1 - 0.017 14.5 5.0 0.099 12.0 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_7 PF12838.2 KFX90037.1 - 0.029 14.7 1.7 0.029 14.7 1.2 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFX90037.1 - 0.044 14.5 0.1 0.044 14.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_16 PF13191.1 KFX90037.1 - 0.048 13.6 0.0 9.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KFX90037.1 - 0.067 12.9 0.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KFX90037.1 - 0.067 12.0 0.1 4.4 6.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KFX90037.1 - 0.084 12.8 0.5 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFX90037.1 - 0.1 12.1 0.2 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFX90037.1 - 0.12 12.2 0.0 9.2 6.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 KFX90037.1 - 0.13 11.3 0.1 0.3 10.1 0.1 1.6 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.4 KFX90037.1 - 0.16 11.4 0.2 0.16 11.4 0.1 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_10 PF13237.1 KFX90037.1 - 0.23 11.2 15.7 0.031 14.0 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.1 KFX90037.1 - 0.25 11.2 1.5 25 4.7 0.0 3.1 2 2 1 3 3 2 0 AAA domain AAA_24 PF13479.1 KFX90037.1 - 0.26 10.8 3.9 0.83 9.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain Fer4_8 PF13183.1 KFX90037.1 - 0.43 10.6 9.3 0.31 11.0 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFX90037.1 - 0.55 10.2 12.9 0.61 10.1 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.10 KFX90037.1 - 0.86 9.2 2.9 18 4.9 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_9 PF13187.1 KFX90037.1 - 1.4 9.2 14.3 0.035 14.3 1.5 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain FF PF01846.14 KFX90038.1 - 2.8e-51 171.2 14.1 6.4e-15 54.8 0.4 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.21 KFX90038.1 - 1.6e-18 66.2 11.9 1.6e-10 40.6 1.6 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 KFX90039.1 - 3.5e-73 246.5 0.0 2.3e-72 243.8 0.0 1.9 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Fungal_trans PF04082.13 KFX90040.1 - 2.7e-20 72.3 0.0 4.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90040.1 - 3e-06 27.0 15.8 5.1e-06 26.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KFX90040.1 - 0.04 13.3 35.5 0.069 12.5 24.6 1.3 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 KFX90040.1 - 1.1 8.9 15.4 2.5 7.7 10.7 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 KFX90040.1 - 4.4 5.4 48.4 6.6 4.8 33.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 KFX90041.1 - 1.7e-21 76.2 2.9 1.7e-21 76.2 2.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TSA PF03249.8 KFX90041.1 - 0.02 13.4 1.9 0.03 12.8 1.3 1.1 1 0 0 1 1 1 0 Type specific antigen Mpv17_PMP22 PF04117.7 KFX90042.1 - 3.5e-24 84.2 1.9 3.9e-24 84.0 0.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 KFX90043.1 - 2.7e-150 500.2 1.4 3e-150 500.0 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 KFX90043.1 - 0.16 11.3 0.5 0.46 9.8 0.1 1.9 2 0 0 2 2 2 0 Propionate catabolism activator DSS1_SEM1 PF05160.8 KFX90044.1 - 6.1e-24 83.5 14.7 8.1e-24 83.1 10.2 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family S_layer_N PF05123.7 KFX90044.1 - 0.077 12.6 1.9 0.089 12.4 1.3 1.0 1 0 0 1 1 1 0 S-layer like family, N-terminal region DUF3808 PF10300.4 KFX90045.1 - 2e-134 448.7 2.2 2.6e-134 448.3 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) RINGv PF12906.2 KFX90045.1 - 6.4e-06 26.1 6.9 1.4e-05 24.9 4.8 1.7 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KFX90045.1 - 0.0011 18.8 3.5 0.0035 17.2 2.4 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KFX90045.1 - 0.0021 17.8 5.5 0.0043 16.8 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 KFX90045.1 - 1.3 8.6 4.0 2.9 7.5 2.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NST1 PF13945.1 KFX90046.1 - 3.6e-59 200.0 1.9 3.6e-59 200.0 1.3 4.8 3 1 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 KFX90047.1 - 3.2e-48 163.1 0.0 4.5e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX90047.1 - 3e-15 56.7 0.0 5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX90047.1 - 1.7e-06 27.3 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX90047.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFX90047.1 - 0.029 13.8 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KFX90047.1 - 0.05 12.8 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MRP-L28 PF09812.4 KFX90048.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Bac_small_YrzI PF09501.5 KFX90048.1 - 0.018 14.9 0.4 0.028 14.3 0.3 1.2 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Filament PF00038.16 KFX90049.1 - 0.0028 17.1 6.7 0.0028 17.1 4.7 5.9 4 1 2 6 6 6 3 Intermediate filament protein Reo_sigmaC PF04582.7 KFX90049.1 - 4.1 6.4 21.8 0.79 8.8 0.4 4.3 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF3549 PF12069.3 KFX90049.1 - 4.3 6.0 10.6 0.97 8.1 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Ank_2 PF12796.2 KFX90066.1 - 3.8e-124 405.3 60.1 1.1e-21 76.9 1.2 7.7 1 1 7 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90066.1 - 3.6e-68 222.1 46.8 1.2e-07 31.2 0.0 15.1 14 1 1 15 15 15 11 Ankyrin repeat Ank_4 PF13637.1 KFX90066.1 - 1.6e-49 165.4 21.4 2.1e-10 40.7 0.1 11.4 5 2 7 12 12 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX90066.1 - 6.9e-46 149.6 19.1 5.1e-05 23.1 0.0 14.9 15 0 0 15 15 14 9 Ankyrin repeat Ank_5 PF13857.1 KFX90066.1 - 1.2e-43 146.1 33.0 4.7e-07 29.8 0.5 13.8 5 3 10 15 15 15 11 Ankyrin repeats (many copies) Patatin PF01734.17 KFX90066.1 - 1.3e-22 80.6 0.0 4.7e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase NACHT PF05729.7 KFX90066.1 - 5.4e-08 32.6 0.0 2.4e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KFX90066.1 - 0.0015 18.2 0.1 0.0036 17.0 0.1 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KFX90066.1 - 0.0037 17.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KFX90066.1 - 0.0062 15.4 0.0 0.065 12.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KFX90066.1 - 0.026 14.7 0.0 0.099 12.9 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KFX90066.1 - 0.064 13.5 0.4 0.22 11.8 0.1 2.1 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 KFX90066.1 - 0.11 12.6 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.24 KFX90067.1 - 3.7e-18 65.6 0.0 6.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFX90067.1 - 4.7e-08 33.0 0.2 1.9e-06 27.8 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFX90067.1 - 6.3e-07 29.1 0.1 1.3e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KFX90067.1 - 0.044 13.0 0.0 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AA_permease PF00324.16 KFX90069.1 - 1.4e-132 442.4 36.1 1.7e-132 442.1 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX90069.1 - 4.1e-46 157.3 42.8 4.8e-46 157.1 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2104 PF09877.4 KFX90069.1 - 0.036 14.0 1.0 0.036 14.0 0.7 3.2 4 1 0 4 4 4 0 Predicted membrane protein (DUF2104) Serinc PF03348.10 KFX90069.1 - 1.5 7.4 6.6 8.2 5.0 3.5 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) C2 PF00168.25 KFX90070.1 - 3.3e-68 225.5 1.4 2.2e-17 62.6 0.0 5.7 5 0 0 5 5 5 5 C2 domain Ribosomal_L28e PF01778.12 KFX90071.1 - 1.4e-38 131.9 0.6 1.9e-38 131.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family 3-HAO PF06052.7 KFX90077.1 - 1.4e-08 34.2 0.1 1.4e-08 34.2 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Ctr PF04145.10 KFX90078.1 - 5.1e-30 104.4 10.6 3.2e-29 101.8 7.4 1.8 1 1 0 1 1 1 1 Ctr copper transporter family DUF2681 PF10883.3 KFX90078.1 - 0.18 11.9 1.2 0.22 11.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF2839 PF10999.3 KFX90078.1 - 7.9 6.6 5.7 2.9 7.9 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) WD40 PF00400.27 KFX90081.1 - 4e-28 96.2 14.5 4.3e-08 32.7 0.2 8.3 9 0 0 9 9 9 4 WD domain, G-beta repeat Rep_fac-A_C PF08646.5 KFX90081.1 - 0.18 11.4 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain Fungal_trans_2 PF11951.3 KFX90083.1 - 1.3e-54 185.2 1.7 1.6e-54 185.0 1.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PriCT_2 PF08707.6 KFX90083.1 - 0.14 12.0 3.2 0.24 11.3 1.5 1.9 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Aminotran_1_2 PF00155.16 KFX90084.1 - 5.7e-20 71.5 0.0 7.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFX90084.1 - 8.5e-05 21.2 0.0 0.00011 20.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Axin_b-cat_bind PF08833.5 KFX90084.1 - 0.0047 16.6 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Axin beta-catenin binding domain AA_permease_2 PF13520.1 KFX90085.1 - 1.4e-46 158.9 51.8 1.8e-46 158.5 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX90085.1 - 1.9e-28 99.0 46.1 2.7e-28 98.5 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 KFX90086.1 - 1.4e-49 168.6 0.0 1.7e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX90086.1 - 1.7e-09 38.4 0.0 3.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyoxalase PF00903.20 KFX90087.1 - 1.3e-12 47.8 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX90087.1 - 1.6e-12 47.9 0.1 3.1e-12 47.0 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFX90087.1 - 3.7e-05 23.6 0.0 8.9e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFX90087.1 - 0.00011 22.1 0.1 0.028 14.3 0.1 2.3 1 1 0 1 1 1 1 Glyoxalase-like domain Potex_coat PF06184.6 KFX90088.1 - 0.09 12.1 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Potexvirus coat protein DUF3830 PF12903.2 KFX90089.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Aminotran_4 PF01063.14 KFX90090.1 - 2.1e-24 86.2 0.0 2.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Nucleoporin_FG PF13634.1 KFX90097.1 - 0.007 16.5 94.5 0.011 15.9 26.6 11.6 3 3 5 8 8 8 4 Nucleoporin FG repeat region DUF3484 PF11983.3 KFX90097.1 - 0.12 13.2 0.2 0.12 13.2 0.1 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3484) NUP50 PF08911.6 KFX90097.1 - 0.13 12.6 0.1 0.13 12.6 0.0 8.4 8 1 0 8 8 8 0 NUP50 (Nucleoporin 50 kDa) PAP2 PF01569.16 KFX90107.1 - 4.2e-11 42.6 1.6 6.4e-11 42.0 0.1 2.0 2 1 0 2 2 2 1 PAP2 superfamily WD40 PF00400.27 KFX90108.1 - 7.6e-25 85.8 2.4 5.8e-10 38.6 0.0 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3408 PF11888.3 KFX90108.1 - 0.089 12.7 2.0 0.36 10.7 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) Aminotran_1_2 PF00155.16 KFX90109.1 - 1e-60 205.6 0.0 1.6e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFX90109.1 - 0.0088 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Tmemb_18A PF09771.4 KFX90109.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 AMP-binding PF00501.23 KFX90111.1 - 5.1e-15 54.7 0.0 6.2e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_N PF02776.13 KFX90112.1 - 1.1e-40 138.9 0.0 3e-40 137.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX90112.1 - 4.2e-33 113.9 0.1 9.1e-33 112.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFX90112.1 - 5.2e-20 71.5 0.1 1.5e-19 70.1 0.0 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 KFX90112.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SH3BGR PF04908.10 KFX90113.1 - 0.00022 21.0 0.0 0.00082 19.2 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein CobT PF06213.7 KFX90113.1 - 0.18 10.8 36.1 0.42 9.6 25.0 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 KFX90113.1 - 0.33 8.8 49.0 0.46 8.3 34.0 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 KFX90113.1 - 0.47 8.6 13.1 0.61 8.2 9.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 KFX90113.1 - 8.5 4.2 38.2 12 3.7 26.5 1.2 1 0 0 1 1 1 0 CDC45-like protein 3Beta_HSD PF01073.14 KFX90114.1 - 3.1e-68 229.5 0.0 3.9e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX90114.1 - 2.3e-28 99.2 0.1 3.1e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX90114.1 - 2.8e-15 55.9 0.1 3.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFX90114.1 - 2.2e-14 53.0 0.2 8.2e-12 44.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFX90114.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX90114.1 - 5.6e-10 38.6 0.5 1.4e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFX90114.1 - 9.1e-07 28.9 0.1 1.8e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KFX90114.1 - 0.00011 21.5 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KFX90114.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KFX90114.1 - 0.0014 18.5 0.0 0.0036 17.2 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.11 KFX90114.1 - 0.0032 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Guanylate_kin PF00625.16 KFX90114.1 - 0.0067 15.8 0.0 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Guanylate kinase Glyco_trans_4_2 PF13477.1 KFX90114.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like DapB_N PF01113.15 KFX90114.1 - 0.019 14.9 0.2 0.036 13.9 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ELMO_CED12 PF04727.8 KFX90115.1 - 4.2e-46 156.5 0.1 8.7e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KFX90115.1 - 0.0011 18.7 0.0 0.038 13.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) RTA1 PF04479.8 KFX90116.1 - 3e-42 144.6 6.0 4.4e-42 144.1 4.2 1.2 1 0 0 1 1 1 1 RTA1 like protein CBM_1 PF00734.13 KFX90117.1 - 3.8e-11 42.4 9.7 3.8e-11 42.4 6.7 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Esterase PF00756.15 KFX90117.1 - 6.4e-06 25.7 0.3 6.5e-05 22.4 0.2 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 KFX90117.1 - 1.4e-05 25.0 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX90117.1 - 1.7e-05 24.1 0.1 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KFX90117.1 - 0.00052 19.3 0.1 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KFX90117.1 - 0.00057 19.6 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX90117.1 - 0.00089 18.7 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KFX90117.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cys_Met_Meta_PP PF01053.15 KFX90118.1 - 4e-29 101.0 0.0 4.8e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NmrA PF05368.8 KFX90119.1 - 1.6e-05 24.2 0.0 0.029 13.6 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family Semialdhyde_dh PF01118.19 KFX90119.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX90119.1 - 0.0034 17.2 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 KFX90119.1 - 0.0068 16.4 1.1 0.9 9.5 0.2 2.6 2 1 1 3 3 3 2 NADH(P)-binding LtrA PF06772.6 KFX90120.1 - 2.2e-20 72.8 24.3 4e-20 72.0 16.8 1.4 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PsaL PF02605.10 KFX90120.1 - 0.056 12.9 2.5 0.89 9.0 1.0 2.9 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI Nsp1_C PF05064.8 KFX90120.1 - 0.22 11.1 0.9 19 4.9 0.0 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Alpha-amylase PF00128.19 KFX90121.1 - 4.5e-27 95.2 0.0 6.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFX90121.1 - 3.3e-10 39.9 0.1 8.5e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain MFS_1 PF07690.11 KFX90122.1 - 3e-22 78.8 57.3 5.5e-22 77.9 39.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX90122.1 - 0.074 11.6 37.8 0.38 9.2 8.3 2.3 1 1 0 2 2 2 0 Sugar (and other) transporter LAM_C PF12544.3 KFX90123.1 - 0.00017 21.6 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_14 PF13394.1 KFX90123.1 - 0.0098 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 KFX90123.1 - 0.024 14.7 0.2 0.11 12.6 0.1 2.2 2 1 0 2 2 2 0 Radical SAM superfamily FAD_binding_2 PF00890.19 KFX90124.1 - 2.6e-125 418.5 3.3 3.6e-125 418.0 2.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KFX90124.1 - 5.9e-46 155.4 0.6 1.2e-45 154.5 0.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term zf-GRF PF06839.7 KFX90124.1 - 6.8e-09 35.5 5.4 6.8e-09 35.5 3.7 2.4 2 0 0 2 2 2 1 GRF zinc finger Pyr_redox_2 PF07992.9 KFX90124.1 - 1.1e-06 28.7 0.0 0.0044 16.9 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX90124.1 - 2.7e-05 23.2 0.8 0.017 14.0 1.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 KFX90124.1 - 4.1e-05 22.7 0.4 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFX90124.1 - 0.0011 17.9 0.1 0.0086 15.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFX90124.1 - 0.0063 15.6 0.1 0.013 14.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFX90124.1 - 0.22 9.9 1.8 0.43 8.9 0.4 2.1 3 0 0 3 3 3 0 HI0933-like protein Osmo_CC PF08946.5 KFX90124.1 - 0.42 10.6 3.6 0.18 11.8 0.4 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF3818 PF12825.2 KFX90125.1 - 5e-134 446.2 6.0 1.1e-133 445.1 4.1 1.6 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KFX90125.1 - 2.9e-42 143.5 0.6 7.5e-42 142.1 0.4 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KFX90125.1 - 5.2e-13 48.7 0.1 3.5e-12 46.1 0.0 2.5 2 1 0 2 2 2 1 PX domain Myc_N PF01056.13 KFX90125.1 - 0.0071 15.5 1.9 0.014 14.5 1.3 1.4 1 0 0 1 1 1 1 Myc amino-terminal region Cgr1 PF03879.9 KFX90126.1 - 1e-33 115.7 29.9 1.2e-33 115.5 20.7 1.0 1 0 0 1 1 1 1 Cgr1 family Ndufs5 PF10200.4 KFX90126.1 - 0.24 11.4 10.5 0.43 10.6 6.5 1.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4612 PF15389.1 KFX90126.1 - 0.62 10.6 6.3 0.79 10.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) GAGA_bind PF06217.7 KFX90126.1 - 1 9.2 9.6 1.2 9.0 6.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Silic_transp PF03842.8 KFX90126.1 - 1.9 6.4 4.8 2.1 6.3 3.3 1.0 1 0 0 1 1 1 0 Silicon transporter Vfa1 PF08432.5 KFX90126.1 - 3 7.8 14.0 3.7 7.5 9.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_carr PF00153.22 KFX90127.1 - 4.6e-63 208.9 0.4 8.9e-21 73.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 KFX90128.1 - 3.4e-39 133.7 1.4 4.3e-39 133.3 1.0 1.1 1 0 0 1 1 1 1 TspO/MBR family Glyco_hydro_72 PF03198.9 KFX90131.1 - 2.9e-101 338.5 0.0 3.9e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Metallophos PF00149.23 KFX90142.1 - 1.4e-34 119.2 0.3 7.9e-29 100.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_61 PF03443.9 KFX90144.1 - 8.4e-57 192.4 0.0 1.1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_zinc_N PF00107.21 KFX90145.1 - 2.2e-28 98.4 0.9 3.8e-28 97.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX90145.1 - 4.3e-14 53.5 0.1 1.1e-13 52.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX90145.1 - 6e-11 42.0 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KFX90145.1 - 0.00031 20.7 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KFX90145.1 - 0.081 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rrn6 PF10214.4 KFX90153.1 - 2.3e-13 49.1 1.2 2.6e-13 49.0 0.9 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor adh_short PF00106.20 KFX90154.1 - 1.5e-08 34.7 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX90154.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX90154.1 - 0.11 12.5 0.1 1 9.2 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding PD40 PF07676.7 KFX90155.1 - 1.4e-45 152.3 28.2 1.8e-07 30.6 0.2 9.7 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KFX90155.1 - 3.1e-12 45.7 9.4 0.028 13.0 1.9 7.0 4 2 2 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 KFX90155.1 - 0.0058 15.5 0.0 0.024 13.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) Pectate_lyase22 PF14583.1 KFX90155.1 - 0.0064 14.9 0.5 0.4 9.0 0.0 3.8 4 2 1 5 5 5 1 Oligogalacturonate lyase TruB_C PF09142.6 KFX90155.1 - 0.011 15.3 0.0 3.9 7.1 0.0 4.4 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal Bac_rhamnosid_N PF08531.5 KFX90155.1 - 0.02 14.4 0.1 0.045 13.2 0.1 1.6 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain adh_short PF00106.20 KFX90156.1 - 3.5e-08 33.5 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KFX90156.1 - 7.4e-05 21.8 0.0 0.00065 18.7 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFX90156.1 - 0.00045 20.3 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFX90156.1 - 0.006 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KFX90156.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 KR domain RWD PF05773.17 KFX90156.1 - 0.1 12.4 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 RWD domain COesterase PF00135.23 KFX90157.1 - 2.2e-86 290.6 0.0 3e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX90157.1 - 8.9e-07 28.6 0.0 7.7e-06 25.6 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX90157.1 - 0.00034 19.9 0.3 0.00066 18.9 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sec62 PF03839.11 KFX90161.1 - 8.5e-51 172.5 0.0 8.5e-51 172.5 0.0 1.4 2 0 0 2 2 2 1 Translocation protein Sec62 APC_CDC26 PF10471.4 KFX90161.1 - 0.0092 16.7 3.9 0.097 13.4 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 BRF1 PF07741.8 KFX90161.1 - 0.35 11.1 4.4 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF2763 PF10961.3 KFX90161.1 - 6.3 7.2 10.4 3.9 7.9 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) DUF2183 PF09949.4 KFX90164.1 - 9.8e-17 60.7 0.1 1.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SnoaL_4 PF13577.1 KFX90165.1 - 1.2e-19 70.4 0.0 5.4e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.1 KFX90165.1 - 6.5e-05 23.0 0.0 0.00031 20.9 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 KFX90165.1 - 0.0011 19.4 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 Putative lumazine-binding DUF3129 PF11327.3 KFX90169.1 - 3.4e-41 141.0 11.3 4.3e-41 140.7 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) F-box-like PF12937.2 KFX90170.1 - 7.8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like Rifin_STEVOR PF02009.11 KFX90170.1 - 0.0038 16.9 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Podoplanin PF05808.6 KFX90170.1 - 0.01 15.4 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 1 Podoplanin S1FA PF04689.8 KFX90170.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Adeno_E3_CR2 PF02439.10 KFX90170.1 - 0.22 11.0 3.0 0.43 10.1 2.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 KFX90170.1 - 0.28 10.5 7.8 0.56 9.5 5.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NDUF_B7 PF05676.8 KFX90171.1 - 6.7e-30 102.3 4.2 8.8e-30 101.9 2.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KFX90171.1 - 0.04 13.6 2.6 0.054 13.2 1.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank PF00023.25 KFX90172.1 - 1.5e-14 52.9 3.7 3.1e-06 26.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KFX90172.1 - 7.2e-14 51.8 4.9 1.6e-05 25.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX90172.1 - 1e-11 45.0 1.6 1.4e-05 25.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX90172.1 - 7.4e-10 38.7 0.7 0.0038 17.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 KFX90172.1 - 7.9e-08 31.8 0.0 2.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 KFX90172.1 - 6.8e-05 22.7 2.9 0.047 13.9 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Mannitol_dh_C PF08125.8 KFX90175.1 - 2.6e-48 164.3 0.0 3.9e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KFX90175.1 - 1.3e-22 80.3 0.6 5.7e-22 78.2 0.0 2.2 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain Gla PF00594.15 KFX90175.1 - 0.048 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain UDPG_MGDP_dh_N PF03721.9 KFX90175.1 - 0.068 12.5 0.3 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 KFX90178.1 - 2.2e-58 197.4 0.0 3.2e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90178.1 - 4.3e-30 104.6 0.0 6.6e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX90178.1 - 0.047 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cro PF09048.5 KFX90178.1 - 0.049 13.2 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Cro Kdo PF06293.9 KFX90178.1 - 0.18 10.8 0.1 0.32 10.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.15 KFX90179.1 - 6.1e-10 37.6 0.2 2.9e-08 32.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein DUF2439 PF10382.4 KFX90179.1 - 0.028 14.6 0.1 1.9 8.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) CENP-F_leu_zip PF10473.4 KFX90181.1 - 0.085 12.7 2.7 0.21 11.4 1.9 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mnd1 PF03962.10 KFX90181.1 - 0.12 12.0 0.9 0.25 10.9 0.7 1.5 1 0 0 1 1 1 0 Mnd1 family FTO_CTD PF12934.2 KFX90181.1 - 0.14 11.7 0.3 0.3 10.6 0.2 1.5 1 0 0 1 1 1 0 FTO C-terminal domain IncA PF04156.9 KFX90181.1 - 0.16 11.5 4.1 0.28 10.7 2.8 1.4 1 0 0 1 1 1 0 IncA protein Enolase_C PF00113.17 KFX90183.1 - 1.3e-150 500.3 0.0 1.8e-150 499.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFX90183.1 - 3.2e-58 195.3 0.1 5e-58 194.7 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KFX90183.1 - 0.0081 16.6 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 KFX90183.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like AAA PF00004.24 KFX90184.1 - 4.3e-42 143.4 0.0 7.8e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX90184.1 - 2.5e-06 27.6 0.1 8.1e-05 22.6 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KFX90184.1 - 1.1e-05 25.1 0.1 0.00017 21.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX90184.1 - 1.8e-05 24.7 0.0 4.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFX90184.1 - 1.9e-05 24.8 0.0 0.0021 18.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX90184.1 - 2.4e-05 23.5 0.0 4.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFX90184.1 - 0.00066 19.3 0.1 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KFX90184.1 - 0.0021 17.0 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFX90184.1 - 0.0032 18.2 0.4 0.0094 16.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX90184.1 - 0.006 16.4 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFX90184.1 - 0.0071 15.7 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KFX90184.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFX90184.1 - 0.0086 14.8 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KFX90184.1 - 0.0088 16.3 0.1 0.032 14.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KFX90184.1 - 0.0089 15.2 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFX90184.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 KFX90184.1 - 0.027 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KFX90184.1 - 0.034 13.6 0.0 0.097 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KFX90184.1 - 0.035 13.4 0.2 0.14 11.5 0.1 1.9 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFX90184.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KFX90184.1 - 0.044 13.3 0.1 0.087 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFX90184.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFX90184.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX90184.1 - 0.072 12.7 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 KFX90184.1 - 0.086 11.9 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 1 0 KaiC PhoH PF02562.11 KFX90184.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KFX90184.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFX90184.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFX90184.1 - 0.12 11.9 0.0 0.41 10.3 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 KFX90184.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SIS PF01380.17 KFX90185.1 - 1.4e-51 173.5 0.0 5.1e-28 97.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KFX90185.1 - 6.8e-27 94.1 0.0 4.3e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFX90185.1 - 1.7e-19 70.0 0.0 3.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFX90185.1 - 1.7e-12 47.1 0.0 3.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KFX90185.1 - 7.5e-07 28.1 0.0 1.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF3295 PF11702.3 KFX90193.1 - 4.9e-148 494.2 43.4 6.4e-148 493.8 30.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KFX90193.1 - 1.3e-11 43.8 1.9 3e-11 42.6 1.3 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BAR PF03114.13 KFX90196.1 - 3.6e-49 167.3 5.8 4.5e-49 167.0 4.0 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KFX90196.1 - 2.6e-05 23.2 2.5 3.1e-05 23.0 1.7 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.10 KFX90196.1 - 0.27 11.1 2.9 2.8 7.8 0.9 2.4 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Arfaptin PF06456.8 KFX90196.1 - 0.63 9.3 7.4 2.3 7.4 5.2 2.1 1 1 0 1 1 1 0 Arfaptin-like domain GBP_C PF02841.9 KFX90196.1 - 0.71 9.0 12.2 0.13 11.3 5.1 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF4337 PF14235.1 KFX90196.1 - 1.1 9.0 7.0 2.9 7.6 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) OmpH PF03938.9 KFX90196.1 - 1.5 8.7 7.7 12 5.8 3.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 KFX90196.1 - 5.1 6.0 11.7 0.87 8.5 5.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 O-FucT PF10250.4 KFX90202.1 - 9.1e-11 41.4 0.1 0.00011 21.4 0.0 3.0 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF2881 PF11087.3 KFX90203.1 - 0.2 11.1 1.1 0.34 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) CHAT PF12770.2 KFX90204.1 - 2.3e-30 105.6 0.0 4.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 KFX90204.1 - 1.5e-06 27.7 3.0 0.33 10.6 0.0 6.7 5 2 0 7 7 7 2 TPR repeat HTH_3 PF01381.17 KFX90204.1 - 0.086 12.6 0.2 7 6.5 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix Apc5 PF12862.2 KFX90204.1 - 0.14 11.9 6.8 13 5.7 0.0 5.4 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 DsbC_N PF10411.4 KFX90204.1 - 0.15 11.3 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus E1-E2_ATPase PF00122.15 KFX90205.1 - 2.7e-54 183.6 0.2 5.4e-54 182.6 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 KFX90205.1 - 8.8e-48 160.3 0.0 4.7e-12 45.8 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 KFX90205.1 - 9.5e-47 160.1 2.1 1.2e-46 159.8 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX90205.1 - 9.3e-15 55.2 0.0 2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX90205.1 - 1.6e-05 24.6 2.4 0.00011 21.8 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 KFX90205.1 - 0.11 12.0 3.7 20 4.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) SSF PF00474.12 KFX90206.1 - 1.5e-21 76.5 34.3 2.2e-21 75.9 23.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family zf-trcl PF13451.1 KFX90207.1 - 0.88 9.2 5.7 0.22 11.1 0.9 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain Ribosomal_L37e PF01907.14 KFX90207.1 - 1.1 9.0 6.6 12 5.8 2.8 2.5 2 1 0 2 2 2 0 Ribosomal protein L37e PLU-1 PF08429.6 KFX90208.1 - 0.042 12.7 1.5 0.05 12.4 0.2 1.5 1 1 1 2 2 2 0 PLU-1-like protein NifW PF03206.9 KFX90208.1 - 0.053 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW GrpE PF01025.14 KFX90208.1 - 0.17 11.3 1.6 0.41 10.1 1.1 1.7 1 1 1 2 2 2 0 GrpE IncA PF04156.9 KFX90208.1 - 7.6 6.0 7.8 1.2e+02 2.2 5.4 2.2 1 1 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 KFX90209.1 - 5.5e-11 42.2 11.1 1.3e-05 25.2 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFX90209.1 - 3.7e-10 39.5 11.5 2e-05 24.6 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX90209.1 - 3.7e-07 29.9 9.1 0.0002 21.4 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFX90209.1 - 6.9e-06 26.0 1.5 2e-05 24.6 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX90209.1 - 8e-05 22.6 5.1 0.00012 22.0 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX90209.1 - 0.00089 19.0 7.1 0.004 16.9 1.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFX90209.1 - 0.046 13.8 1.1 0.046 13.8 0.8 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KFX90209.1 - 2.6 7.9 5.9 21 4.9 4.1 2.2 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KFX90209.1 - 4.6 7.6 7.7 14 6.1 1.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Sad1_UNC PF07738.8 KFX90212.1 - 1.8e-36 124.9 0.0 2.9e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal FUN14 PF04930.10 KFX90213.1 - 4.5e-08 33.2 1.3 5e-07 29.9 1.1 2.2 2 1 0 2 2 2 1 FUN14 family Xpo1 PF08389.7 KFX90214.1 - 0.0006 19.7 0.3 0.023 14.5 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein RRM_2 PF04059.7 KFX90215.1 - 4e-40 135.7 0.3 7.1e-40 134.9 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 KFX90215.1 - 0.0001 21.8 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX90215.1 - 0.015 15.2 0.0 7.3 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX90215.1 - 0.048 13.5 0.1 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.7 KFX90216.1 - 2.6e-123 411.2 0.5 2.6e-123 411.2 0.3 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 KFX90216.1 - 0.00078 19.3 6.0 0.00078 19.3 4.2 3.3 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 KFX90216.1 - 0.0013 18.3 6.3 0.0013 18.3 4.3 2.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 KFX90216.1 - 0.003 17.5 7.1 0.0083 16.0 3.7 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG7 PF10191.4 KFX90216.1 - 0.026 12.4 10.5 0.3 8.9 3.6 2.8 3 0 0 3 3 3 0 Golgi complex component 7 (COG7) DUF2450 PF10475.4 KFX90216.1 - 0.046 12.6 12.4 0.011 14.6 5.9 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 KFX90216.1 - 0.11 12.3 4.4 0.25 11.2 1.2 2.9 2 0 0 2 2 2 0 Vps51/Vps67 Sec5 PF15469.1 KFX90216.1 - 0.54 9.9 7.2 0.48 10.1 2.0 2.7 2 1 0 2 2 2 0 Exocyst complex component Sec5 CBFD_NFYB_HMF PF00808.18 KFX90217.1 - 1.4e-19 69.8 0.6 2.4e-19 69.1 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX90217.1 - 4e-12 46.0 1.7 3.5e-11 43.0 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PAT1 PF09770.4 KFX90217.1 - 0.022 13.0 12.6 0.031 12.5 8.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-X PF09415.5 KFX90217.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.6 KFX90218.1 - 2.3e-31 107.7 0.3 4.8e-31 106.7 0.1 1.6 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing TGF_beta_GS PF08515.7 KFX90218.1 - 0.015 14.6 3.5 0.039 13.2 2.5 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif tRNA-synt_1b PF00579.20 KFX90219.1 - 3.4e-65 220.0 0.0 5.8e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 KFX90219.1 - 2.7e-23 81.6 0.0 9.4e-23 79.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Abhydrolase_6 PF12697.2 KFX90220.1 - 6.6e-31 107.9 0.0 8.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX90220.1 - 2.8e-21 76.1 0.0 1.9e-20 73.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX90220.1 - 3e-14 53.0 0.0 4.5e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFX90220.1 - 2.7e-05 23.8 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KFX90220.1 - 4.9e-05 23.6 0.0 5.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 KFX90220.1 - 0.00029 19.4 0.0 0.00037 19.0 0.0 1.4 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 KFX90220.1 - 0.00097 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 KFX90220.1 - 0.0018 17.1 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.8 KFX90220.1 - 0.038 13.5 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.3 KFX90220.1 - 0.051 13.4 0.2 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 KFX90220.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KFX90220.1 - 0.086 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KFX90220.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Ribosomal_S3Ae PF01015.13 KFX90221.1 - 7.9e-81 270.0 6.4 1.3e-80 269.3 4.5 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.17 KFX90221.1 - 5.8e-42 142.8 0.0 1.2e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX90221.1 - 7.9e-07 29.5 0.0 2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX90221.1 - 5.7e-06 25.6 0.0 1.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX90221.1 - 0.0069 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_CH_N PF12471.3 KFX90222.1 - 3.1e-89 297.7 0.0 4.8e-89 297.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KFX90222.1 - 4.3e-16 58.6 0.0 7.3e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4540 PF15073.1 KFX90222.1 - 0.062 13.8 1.7 0.15 12.5 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4540) Elf1 PF05129.8 KFX90223.1 - 1.7e-27 94.8 2.2 2.4e-27 94.4 1.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPRTase PF14681.1 KFX90224.1 - 7.1e-78 260.5 0.0 8.8e-78 260.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFX90224.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KFX90224.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 KFX90225.1 - 1.6e-20 73.1 0.1 1.1e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 KFX90226.1 - 8e-46 155.3 1.0 9.1e-46 155.1 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX90226.1 - 6e-15 55.7 0.3 8.7e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX90226.1 - 2e-08 33.7 0.0 2.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX90226.1 - 8.5e-08 31.8 0.2 2.3e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX90226.1 - 7e-06 25.9 0.1 9.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX90226.1 - 0.0015 17.7 0.1 0.0028 16.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KFX90226.1 - 0.011 15.6 0.0 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 KFX90226.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFX90226.1 - 0.028 13.6 0.0 0.34 10.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KFX90226.1 - 0.18 11.5 0.7 0.55 9.8 0.5 1.9 1 1 0 1 1 1 0 Archaeal ATPase tRNA-synt_2b PF00587.20 KFX90227.1 - 2.1e-36 125.0 0.1 3.5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFX90227.1 - 1.3e-19 70.1 7.4 1.3e-19 70.1 5.2 2.2 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KFX90227.1 - 0.064 12.9 7.0 0.044 13.4 3.4 1.8 2 0 0 2 2 2 0 Mnd1 family P5-ATPase PF12409.3 KFX90228.1 - 2.1e-36 124.3 0.0 2.1e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 KFX90228.1 - 3.4e-29 102.4 0.0 6.9e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFX90228.1 - 6.2e-27 94.1 0.0 1.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFX90228.1 - 2e-13 51.2 0.0 5.7e-09 36.6 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX90228.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX90228.1 - 0.2 11.1 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAP PF00956.13 KFX90229.1 - 3.8e-89 298.0 10.0 3.8e-89 298.0 7.0 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 KFX90229.1 - 0.17 11.7 20.5 0.54 10.1 8.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit 2-Hacid_dh_C PF02826.14 KFX90230.1 - 2.3e-51 173.4 0.0 3.5e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX90230.1 - 1.3e-29 102.3 0.1 2e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX90230.1 - 7.9e-05 22.5 0.2 0.0007 19.4 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KFX90230.1 - 0.0012 18.7 0.3 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 KFX90230.1 - 0.0016 17.8 0.2 0.015 14.7 0.1 2.6 1 1 0 1 1 1 1 ACT domain SNF2_N PF00176.18 KFX90231.1 - 6.5e-42 143.3 0.0 1.1e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX90231.1 - 1.3e-14 53.7 0.0 6.6e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_14 PF13173.1 KFX90231.1 - 0.072 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain GSH_synth_ATP PF03917.12 KFX90232.1 - 7.5e-113 376.8 0.0 9.3e-113 376.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KFX90232.1 - 1.4e-34 118.3 0.0 2.4e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3454 PF11936.3 KFX90233.1 - 0.96 9.6 7.6 2 8.6 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) SSB PF00436.20 KFX90234.1 - 5.1e-18 64.8 0.0 6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4203 PF13886.1 KFX90235.1 - 2.8e-34 118.4 24.4 4.3e-34 117.8 16.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) LysM PF01476.15 KFX90236.1 - 3.5e-16 58.8 3.9 0.001 18.9 0.0 4.3 4 0 0 4 4 4 4 LysM domain HTH_Tnp_1 PF01527.15 KFX90236.1 - 0.012 15.5 0.0 26 4.8 0.0 3.2 3 0 0 3 3 3 0 Transposase DUF1153 PF06627.6 KFX90236.1 - 0.026 14.3 0.1 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) UPF0203 PF05254.7 KFX90236.1 - 0.43 10.4 13.1 9.9 6.1 0.7 4.0 3 3 0 3 3 3 0 Uncharacterised protein family (UPF0203) PH PF00169.24 KFX90239.1 - 7.2e-05 22.9 0.0 0.001 19.2 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFX90239.1 - 0.0031 17.6 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Actin PF00022.14 KFX90242.1 - 4.6e-96 321.6 0.0 5.4e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Actin G-alpha PF00503.15 KFX90246.1 - 9.1e-134 445.9 5.0 1.1e-133 445.7 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFX90246.1 - 1.7e-15 56.7 2.4 9.2e-11 41.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KFX90246.1 - 5.5e-05 22.6 0.1 0.00024 20.5 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KFX90246.1 - 0.002 18.6 0.7 3.1 8.3 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KFX90246.1 - 0.0045 16.1 5.1 0.046 12.8 0.1 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KFX90246.1 - 0.0097 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KFX90246.1 - 0.021 14.2 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KFX90246.1 - 0.055 13.7 0.5 0.097 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain Mog1 PF04603.7 KFX90246.1 - 0.061 13.2 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Ran-interacting Mog1 protein MCM PF00493.18 KFX90246.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 KFX90246.1 - 0.091 12.7 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KFX90246.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Uds1 PF15456.1 KFX90250.1 - 5.9e-43 145.8 2.8 8.4e-43 145.3 1.9 1.2 1 0 0 1 1 1 1 Up-regulated During Septation HR1 PF02185.11 KFX90250.1 - 8.9e-06 25.3 0.5 1.8e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Hr1 repeat AIG2 PF06094.7 KFX90252.1 - 1.7e-15 57.3 0.0 3.4e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 AIG2-like family Chitin_bind_3 PF03067.10 KFX90254.1 - 0.006 16.8 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Chitin binding domain Glyco_hydro_61 PF03443.9 KFX90254.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.3 KFX90255.1 - 1.3e-38 130.9 10.4 6.3e-25 87.1 1.8 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) RR_TM4-6 PF06459.7 KFX90255.1 - 0.47 10.3 0.2 0.73 9.6 0.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0029 PF01205.14 KFX90256.1 - 9.7e-31 105.7 0.0 1.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KFX90256.1 - 1.1e-07 31.7 0.0 6.5e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 RWD domain alpha-hel2 PF14456.1 KFX90256.1 - 0.018 13.8 0.2 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 AMP-binding PF00501.23 KFX90259.1 - 1.7e-15 56.3 0.1 1.3e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Hepatitis_core PF00906.15 KFX90259.1 - 0.13 11.8 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Hepatitis core antigen Flavodoxin_1 PF00258.20 KFX90261.1 - 1.1e-28 100.0 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KFX90261.1 - 5.7e-06 25.9 0.0 9.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain RNB PF00773.14 KFX90272.1 - 1.4e-55 188.8 0.0 2.9e-55 187.8 0.0 1.5 1 1 0 1 1 1 1 RNB domain ThiS PF02597.15 KFX90273.1 - 7.6e-08 32.6 0.0 3.1e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 ThiS family Zn_clus PF00172.13 KFX90273.1 - 0.0001 22.1 12.4 0.00017 21.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX90273.1 - 0.0011 17.8 1.5 0.0031 16.4 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DAD PF02109.11 KFX90274.1 - 4e-50 168.6 2.9 4.9e-50 168.3 2.0 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.1 KFX90274.1 - 0.041 13.5 0.6 0.071 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Tmemb_14 PF03647.8 KFX90275.1 - 1.4e-23 83.0 8.9 1.6e-23 82.8 6.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Transglut_core2 PF13369.1 KFX90275.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2416 PF10315.4 KFX90275.1 - 0.1 12.8 2.3 0.26 11.5 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) GBP_PSP PF02425.10 KFX90275.1 - 0.53 9.8 2.3 0.95 9.0 1.6 1.4 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Cmc1 PF08583.5 KFX90276.1 - 1.7e-17 62.9 2.9 2e-17 62.7 2.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Flu_B_M2 PF04772.7 KFX90276.1 - 0.026 14.5 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Prefoldin_2 PF01920.15 KFX90277.1 - 1.9e-25 88.7 5.8 2.2e-25 88.4 4.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 KFX90277.1 - 0.0083 15.8 1.8 0.013 15.1 1.3 1.3 1 1 0 1 1 1 1 Mnd1 family DUF2205 PF10224.4 KFX90277.1 - 0.031 13.8 1.0 0.031 13.8 0.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) STAT_alpha PF01017.15 KFX90277.1 - 0.048 13.3 3.5 0.067 12.9 2.4 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain V_ATPase_I PF01496.14 KFX90277.1 - 0.055 11.3 1.1 0.063 11.1 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_B562 PF07361.6 KFX90277.1 - 0.068 13.5 1.6 0.068 13.5 1.1 1.9 2 0 0 2 2 2 0 Cytochrome b562 TMP_2 PF06791.8 KFX90277.1 - 0.076 12.6 0.1 0.091 12.3 0.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein Tho2 PF11262.3 KFX90277.1 - 0.33 9.9 2.2 6 5.8 0.8 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4200 PF13863.1 KFX90277.1 - 0.84 9.5 7.8 1.2 9.0 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_32 PF13654.1 KFX90277.1 - 1.1 7.8 5.2 1.9 7.0 3.6 1.5 1 1 0 1 1 1 0 AAA domain Prefoldin PF02996.12 KFX90277.1 - 1.2 8.8 7.1 6.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 KFX90277.1 - 1.6 8.2 5.1 3.8 7.0 3.5 1.6 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 KFX90277.1 - 4 7.2 6.4 2.6 7.8 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TMF_DNA_bd PF12329.3 KFX90277.1 - 4.2 7.2 12.3 0.73 9.6 2.3 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RRN3 PF05327.6 KFX90278.1 - 7e-177 588.9 0.0 7e-177 588.9 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.20 KFX90279.1 - 9.7e-55 185.5 0.0 1.3e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90279.1 - 3.5e-38 131.1 0.0 5.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX90279.1 - 0.0059 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX90279.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX90279.1 - 0.0079 15.1 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Asp_protease_2 PF13650.1 KFX90280.1 - 1.9e-06 28.3 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KFX90280.1 - 0.0051 16.7 0.0 0.0085 15.9 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFX90280.1 - 0.0079 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFX90281.1 - 1e-08 35.5 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KFX90281.1 - 0.0003 20.6 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFX90281.1 - 0.059 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pkinase PF00069.20 KFX90282.1 - 1.3e-70 237.4 0.0 1.9e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90282.1 - 7.1e-43 146.5 0.0 1e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_3 PF01494.14 KFX90282.1 - 1.1e-24 87.1 0.0 6e-23 81.4 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Kinase-like PF14531.1 KFX90282.1 - 1.6e-11 43.6 0.0 2.9e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 KFX90282.1 - 5.6e-07 29.4 0.2 0.00068 19.5 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Lycopene_cycl PF05834.7 KFX90282.1 - 1.3e-05 24.3 0.2 0.00018 20.5 0.0 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX90282.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Kdo PF06293.9 KFX90282.1 - 0.00092 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Thi4 PF01946.12 KFX90282.1 - 0.0051 15.9 0.0 0.039 13.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KFX90282.1 - 0.0077 14.7 0.1 0.017 13.5 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 KFX90282.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 KFX90282.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 KFX90282.1 - 0.014 14.0 0.0 0.11 11.0 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KFX90282.1 - 0.045 13.7 0.1 0.13 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain OPA3 PF07047.7 KFX90283.1 - 3.5e-36 123.9 5.0 7.5e-36 122.8 3.5 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) AIF-MLS PF14962.1 KFX90283.1 - 0.12 11.9 8.8 1.3 8.6 3.4 2.2 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Rootletin PF15035.1 KFX90283.1 - 0.69 9.8 13.6 3.2 7.6 9.4 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SBDS PF01172.13 KFX90287.1 - 1.6e-25 88.6 1.0 2e-25 88.3 0.7 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HsdM_N PF12161.3 KFX90287.1 - 0.094 13.1 0.2 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain RhoGEF PF00621.15 KFX90288.1 - 2.4e-24 86.1 0.0 3.6e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Curto_V3 PF07436.6 KFX90288.1 - 0.083 13.0 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Curtovirus V3 protein DEAD PF00270.24 KFX90289.1 - 1e-40 138.9 0.0 8.6e-40 135.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX90289.1 - 3.2e-25 87.7 0.2 8.1e-25 86.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 KFX90289.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2986 PF11661.3 KFX90289.1 - 2.9 8.2 8.6 0.35 11.2 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Mnd1 PF03962.10 KFX90291.1 - 7e-46 156.2 4.3 9.5e-46 155.8 3.0 1.1 1 0 0 1 1 1 1 Mnd1 family zf-CSL PF05207.8 KFX90291.1 - 1.2e-18 66.3 0.7 3.2e-18 64.9 0.5 1.8 2 0 0 2 2 2 1 CSL zinc finger DnaJ PF00226.26 KFX90291.1 - 1e-13 50.8 0.3 2.6e-13 49.4 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain IncA PF04156.9 KFX90291.1 - 0.0026 17.3 5.2 0.004 16.7 3.6 1.4 1 0 0 1 1 1 1 IncA protein TBPIP PF07106.8 KFX90291.1 - 0.0085 15.6 3.8 0.026 14.0 2.2 1.9 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PEP-utilisers_N PF05524.8 KFX90291.1 - 0.094 12.5 6.6 0.12 12.2 2.6 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Erp_C PF06780.6 KFX90291.1 - 0.099 12.4 8.0 2.4 7.9 0.5 2.3 1 1 1 2 2 2 0 Erp protein C-terminus Poty_PP PF08440.5 KFX90291.1 - 0.28 10.2 1.5 1.3 8.0 0.2 2.0 1 1 0 2 2 2 0 Potyviridae polyprotein CorA PF01544.13 KFX90291.1 - 2.6 6.9 6.1 3.9 6.4 4.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ATP_bind_4 PF01902.12 KFX90293.1 - 2.8e-13 49.7 0.0 1.3e-06 27.9 0.0 3.0 3 0 0 3 3 3 3 ATP-binding region Herpes_capsid PF06112.6 KFX90293.1 - 0.81 9.7 3.8 1.7 8.6 2.0 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Med5 PF08689.5 KFX90308.1 - 4.7e-203 676.7 0.0 5.7e-203 676.4 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF3534 PF12053.3 KFX90308.1 - 0.032 14.1 0.0 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) XRN_N PF03159.13 KFX90309.1 - 3e-103 344.3 0.1 4.7e-103 343.6 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.27 KFX90310.1 - 2.5e-40 134.9 4.2 9.1e-10 38.0 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFX90310.1 - 2.4e-30 104.2 1.1 5.9e-30 102.9 0.8 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Glyco_transf_20 PF00982.16 KFX90314.1 - 6.1e-147 489.9 0.0 1.1e-146 489.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KFX90314.1 - 1.5e-78 262.9 0.0 3.5e-78 261.7 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 KFX90314.1 - 0.0062 16.6 0.0 0.023 14.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KFX90314.1 - 0.01 15.2 0.0 0.069 12.5 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KFX90314.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain MFS_1 PF07690.11 KFX90315.1 - 4.1e-24 84.9 25.4 5e-24 84.6 17.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.6 KFX90315.1 - 1.3 8.2 11.8 0.2 10.9 2.3 3.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1129) Rad52_Rad22 PF04098.10 KFX90318.1 - 3.2e-62 208.8 0.0 4.3e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PAT1 PF09770.4 KFX90318.1 - 0.92 7.6 18.9 1.2 7.3 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KFX90318.1 - 3.9 7.2 8.4 6.3 6.5 5.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.1 KFX90324.1 - 3.4 5.9 10.2 4.2 5.6 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WD40 PF00400.27 KFX90325.1 - 1.6e-60 198.9 25.5 4.5e-11 42.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX90325.1 - 3e-05 22.3 4.0 0.086 10.9 0.1 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFX90325.1 - 0.02 13.2 0.1 3.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain TAF8_C PF10406.4 KFX90326.1 - 6.6e-18 64.5 1.0 6.6e-18 64.5 0.7 2.2 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KFX90326.1 - 1.5e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Mitochondr_Som1 PF11093.3 KFX90327.1 - 5.4e-13 48.5 0.0 6.1e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DAP3 PF10236.4 KFX90328.1 - 2.9e-47 161.1 0.0 3.2e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RhoGAP PF00620.22 KFX90329.1 - 2.6e-28 98.5 0.0 4.5e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MutS_V PF00488.16 KFX90330.1 - 2.7e-85 285.5 0.0 4.1e-85 284.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX90330.1 - 1.6e-40 139.0 0.8 2.8e-40 138.2 0.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFX90330.1 - 2.8e-27 94.9 0.0 8.1e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KFX90330.1 - 8.2e-08 32.3 0.1 2.9e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KFX90330.1 - 4.1e-06 26.8 0.0 1.6e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV Pyr_redox_3 PF13738.1 KFX90331.1 - 3e-15 56.8 0.0 7.6e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX90331.1 - 5e-13 48.0 0.0 9.3e-07 27.4 0.0 3.4 4 0 0 4 4 4 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX90331.1 - 1.9e-08 34.3 0.0 4.9e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX90331.1 - 2.6e-08 33.7 0.0 5.2e-07 29.5 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX90331.1 - 1.6e-07 31.2 0.0 6e-06 26.1 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX90331.1 - 2.4e-06 27.8 0.0 1.5 9.2 0.0 3.4 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX90331.1 - 3e-06 26.4 0.0 1.4e-05 24.2 0.0 2.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFX90331.1 - 0.011 14.7 0.3 0.029 13.4 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 KFX90331.1 - 0.014 14.5 0.2 0.056 12.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX90331.1 - 0.13 10.7 0.2 0.64 8.4 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KFX90331.1 - 0.22 10.3 0.0 0.48 9.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain P12 PF12669.2 KFX90332.1 - 1.5 9.1 4.6 5.9 7.1 3.2 2.1 1 0 0 1 1 1 0 Virus attachment protein p12 family CFEM PF05730.6 KFX90332.1 - 3.8 7.4 11.4 7.8 6.3 7.9 1.6 1 1 0 1 1 1 0 CFEM domain DUF1903 PF08991.5 KFX90334.1 - 2.3e-05 24.4 0.6 2.8e-05 24.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KFX90334.1 - 0.00011 22.0 4.2 0.00039 20.2 2.9 1.9 1 1 1 2 2 2 1 CHCH domain YqzE PF14038.1 KFX90334.1 - 0.02 14.6 1.2 0.87 9.3 0.2 2.1 2 0 0 2 2 2 0 YqzE-like protein Cmc1 PF08583.5 KFX90334.1 - 0.025 14.3 3.4 0.55 10.0 0.4 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 KFX90334.1 - 0.068 13.0 3.6 0.26 11.1 2.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 KFX90334.1 - 0.2 11.6 3.0 0.45 10.6 2.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CBM_1 PF00734.13 KFX90335.1 - 1.8e-13 49.9 14.0 1.8e-13 49.9 9.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain PhoPQ_related PF10142.4 KFX90335.1 - 0.12 10.8 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 KFX90335.1 - 0.23 9.9 0.1 0.41 9.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Methyltransf_15 PF09445.5 KFX90336.1 - 2.6e-40 137.6 0.0 6e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Lipase_GDSL_2 PF13472.1 KFX90336.1 - 3.7e-15 56.4 0.7 1.2e-14 54.8 0.5 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX90336.1 - 2.2e-13 50.5 1.8 4.4e-13 49.6 0.4 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Met_10 PF02475.11 KFX90336.1 - 3.7e-08 33.2 0.0 8.4e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KFX90336.1 - 4.7e-08 33.5 0.5 3.9e-07 30.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KFX90336.1 - 1.2e-06 28.2 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KFX90336.1 - 3.6e-05 23.2 0.2 0.00029 20.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KFX90336.1 - 0.00012 22.1 0.0 0.00037 20.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90336.1 - 0.0017 17.9 0.3 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DNA_methylase PF00145.12 KFX90336.1 - 0.0093 15.1 0.2 0.0093 15.1 0.1 2.3 2 1 0 2 2 1 1 C-5 cytosine-specific DNA methylase MTS PF05175.9 KFX90336.1 - 0.08 12.3 1.2 0.19 11.0 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase small domain IncA PF04156.9 KFX90336.1 - 1.8 8.1 6.7 4.3 6.8 4.7 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KFX90336.1 - 1.8 6.3 6.5 2.4 5.9 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GRASP55_65 PF04495.9 KFX90337.1 - 5.2e-46 156.0 0.0 1.4e-44 151.4 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Ribosomal_60s PF00428.14 KFX90337.1 - 3.7 8.0 5.6 1.1 9.6 0.4 2.3 2 1 0 2 2 2 0 60s Acidic ribosomal protein Dopey_N PF04118.9 KFX90338.1 - 1e-116 389.0 0.1 2.4e-115 384.5 0.0 2.9 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.9 KFX90339.1 - 3e-114 381.8 0.0 3.7e-114 381.5 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Meleagrin PF08189.6 KFX90339.1 - 0.23 10.9 0.6 0.4 10.1 0.4 1.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family FAA_hydrolase_N PF09298.6 KFX90347.1 - 0.09 12.7 1.4 0.21 11.5 0.4 1.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal RR_TM4-6 PF06459.7 KFX90347.1 - 0.18 11.6 5.5 0.3 10.9 3.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF676 PF05057.9 KFX90348.1 - 9.6e-50 168.8 0.0 1.4e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFX90348.1 - 1.1e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX90348.1 - 0.00039 20.1 0.0 0.00061 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX90348.1 - 0.0022 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFX90348.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 KFX90348.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CMAS PF02353.15 KFX90350.1 - 2.3e-59 200.7 0.0 2.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFX90350.1 - 1.3e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX90350.1 - 3.6e-09 36.9 0.0 8.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90350.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX90350.1 - 0.00044 20.5 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX90350.1 - 0.0013 19.1 0.0 0.004 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX90350.1 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFX90350.1 - 0.0036 17.8 0.1 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX90350.1 - 0.0054 16.7 0.0 0.019 14.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 KFX90350.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 KFX90350.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) EF-hand_4 PF12763.2 KFX90351.1 - 2.7e-25 88.1 0.0 4.3e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 KFX90351.1 - 1.8e-06 27.3 0.5 4.7e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 KFX90351.1 - 2.9e-06 27.2 85.7 3.2e-05 23.8 22.8 6.7 4 2 2 6 6 6 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 KFX90351.1 - 0.0033 17.5 0.0 0.62 10.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFX90351.1 - 0.013 14.7 0.0 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KFX90351.1 - 0.1 12.5 0.1 5.4 7.1 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain DUF2681 PF10883.3 KFX90352.1 - 0.18 12.0 0.7 0.29 11.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) RAMP4 PF06624.7 KFX90353.1 - 6.7e-08 31.9 0.1 7.9e-08 31.7 0.1 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 MRAP PF15183.1 KFX90353.1 - 0.57 9.8 3.5 0.72 9.4 0.3 2.0 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family SMAP PF15477.1 KFX90354.1 - 5.2e-17 61.8 2.6 5.2e-17 61.8 1.8 4.8 2 1 0 2 2 2 1 Small acidic protein family CDC27 PF09507.5 KFX90354.1 - 4.4 6.4 63.1 6.9 5.7 43.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF572 PF04502.8 KFX90354.1 - 6.9 5.7 44.9 9.4 5.3 31.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Adaptin_N PF01602.15 KFX90355.1 - 1.2e-78 264.7 0.0 1.8e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFX90355.1 - 0.22 11.3 1.6 14 5.5 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_11 PF13414.1 KFX90356.1 - 1.2e-08 34.4 2.0 9.6e-05 21.9 0.1 4.0 3 1 2 5 5 5 2 TPR repeat TPR_14 PF13428.1 KFX90356.1 - 2.4e-08 33.8 1.4 0.0079 16.7 0.2 5.2 3 1 3 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX90356.1 - 6.9e-07 29.7 0.5 0.00038 21.0 0.2 4.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90356.1 - 2.7e-06 27.6 0.6 0.0025 18.1 0.2 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX90356.1 - 4.9e-06 26.0 0.7 0.0036 17.0 0.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX90356.1 - 7.4e-06 25.8 4.0 0.2 11.6 0.1 4.4 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX90356.1 - 2.6e-05 24.0 0.3 0.04 14.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX90356.1 - 0.00037 20.0 0.0 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX90356.1 - 0.008 16.0 0.9 0.026 14.3 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX90356.1 - 0.028 14.8 1.2 15 6.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX90356.1 - 0.046 13.3 0.0 5.3 6.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FmrO PF07091.6 KFX90356.1 - 0.061 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ubiquitin_3 PF14836.1 KFX90365.1 - 0.1 12.2 1.2 0.21 11.2 0.8 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain CBM_1 PF00734.13 KFX90366.1 - 1e-12 47.4 21.2 1.9e-09 36.9 3.3 3.4 4 0 0 4 4 4 2 Fungal cellulose binding domain DUF2613 PF11021.3 KFX90367.1 - 0.0093 15.6 2.9 0.039 13.6 2.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) HET PF06985.6 KFX90371.1 - 6.6e-24 84.6 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DDHD PF02862.12 KFX90373.1 - 0.34 10.6 4.5 0.45 10.2 3.1 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 KFX90373.1 - 2.9 5.8 11.5 3.2 5.6 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.22 KFX90381.1 - 2.4e-18 65.6 0.0 4.3e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein YtxH PF12732.2 KFX90381.1 - 0.046 14.0 0.6 0.083 13.2 0.4 1.4 1 0 0 1 1 1 0 YtxH-like protein Glyoxalase PF00903.20 KFX90400.1 - 4.8e-23 81.5 0.2 4.6e-15 55.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFX90400.1 - 1e-13 51.2 0.1 6.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX90400.1 - 7.1e-11 42.6 0.0 2.7e-05 24.7 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KFX90400.1 - 8.5e-08 32.2 0.1 2.2e-06 27.6 0.1 2.7 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KFX90400.1 - 7.7e-07 29.1 0.2 0.043 13.7 0.1 3.5 2 2 0 2 2 2 2 Glyoxalase-like domain TPR_11 PF13414.1 KFX90401.1 - 4.7e-05 22.9 0.7 0.00067 19.2 0.3 2.2 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.1 KFX90401.1 - 0.088 13.0 0.1 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SPC22 PF04573.7 KFX90404.1 - 6e-29 100.5 0.0 1.5e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase subunit TRAPPC10 PF12584.3 KFX90406.1 - 3.7e-22 78.4 0.0 7.2e-21 74.2 0.0 2.5 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Methyltransf_23 PF13489.1 KFX90406.1 - 1.8e-18 66.7 0.0 3.4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX90406.1 - 3.8e-08 33.6 0.0 1.1e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX90406.1 - 1e-05 26.0 0.0 3.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90406.1 - 1.7e-05 24.4 0.0 4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Foie-gras_1 PF11817.3 KFX90406.1 - 6.2e-05 22.6 0.4 0.00015 21.3 0.3 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 Methyltransf_12 PF08242.7 KFX90406.1 - 0.00012 22.4 0.0 0.0012 19.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX90406.1 - 0.001 19.3 0.0 0.0034 17.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX90406.1 - 0.0076 15.6 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFX90406.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KFX90406.1 - 0.14 11.2 0.0 0.41 9.6 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KFX90406.1 - 0.42 9.6 0.0 0.73 8.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HlyIII PF03006.15 KFX90407.1 - 1.6e-57 194.5 17.1 1.9e-57 194.2 11.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF349 PF03993.7 KFX90407.1 - 2.8 8.1 4.9 18 5.5 0.1 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) FimP PF09766.4 KFX90408.1 - 2.2e-26 92.7 5.7 2.9e-26 92.3 4.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 KFX90408.1 - 0.0032 17.2 0.3 0.0032 17.2 0.2 2.9 2 1 1 3 3 3 1 K-box region GOLGA2L5 PF15070.1 KFX90408.1 - 0.0054 15.2 4.9 0.0066 14.9 3.4 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF4200 PF13863.1 KFX90408.1 - 0.043 13.7 0.6 0.043 13.7 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) MIT PF04212.13 KFX90408.1 - 0.078 12.8 2.9 0.21 11.5 2.0 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Cortex-I_coil PF09304.5 KFX90408.1 - 0.2 11.7 9.6 1.7 8.7 2.3 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil IMD PF08397.6 KFX90408.1 - 0.9 8.8 5.3 0.97 8.6 0.1 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain APG6 PF04111.7 KFX90408.1 - 3.6 6.5 10.2 6.2 5.7 1.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 KFX90408.1 - 4 6.6 12.6 2.5 7.2 2.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3435 PF11917.3 KFX90409.1 - 1.4e-07 30.5 0.1 3e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MFS_1 PF07690.11 KFX90413.1 - 4.4e-22 78.2 18.9 2.4e-15 56.1 7.2 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KFX90414.1 - 0.016 15.5 1.1 0.046 14.0 0.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Fibrillarin_2 PF10113.4 KFX90414.1 - 0.085 11.1 0.2 0.1 10.8 0.1 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein zf-C2H2 PF00096.21 KFX90414.1 - 0.091 13.1 0.9 0.25 11.7 0.6 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFX90414.1 - 0.17 12.1 1.0 0.34 11.1 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TPR_12 PF13424.1 KFX90415.1 - 2.2e-25 88.3 13.2 3.5e-09 36.4 0.3 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFX90415.1 - 1.1e-11 44.1 6.8 0.049 13.5 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFX90415.1 - 5.8e-07 28.8 2.1 1.3 8.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90415.1 - 2.7e-06 26.7 7.2 0.064 13.0 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX90415.1 - 9.8e-05 21.9 7.9 0.036 13.7 0.1 3.8 3 1 1 4 4 4 2 TPR repeat Apc3 PF12895.2 KFX90415.1 - 0.00029 20.9 0.5 0.0078 16.3 0.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFX90415.1 - 0.00045 19.9 7.0 12 6.1 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX90415.1 - 0.041 14.0 1.4 53 4.3 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX90415.1 - 1.1 10.0 5.4 1.1e+02 3.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Beta-lactamase PF00144.19 KFX90416.1 - 7.5e-46 156.6 0.0 8.8e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX90416.1 - 0.0032 16.7 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF202 PF02656.10 KFX90423.1 - 1.3e-24 86.1 1.2 1.3e-24 86.1 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SH3_1 PF00018.23 KFX90423.1 - 1.3e-11 43.6 0.6 1.9e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFX90423.1 - 1.4e-10 40.5 0.1 3.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX90423.1 - 6.9e-07 28.6 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_UL37_2 PF07413.6 KFX90423.1 - 0.027 13.2 0.6 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 Pex14_N PF04695.8 KFX90423.1 - 0.3 11.1 15.7 0.8 9.7 1.9 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gemini_mov PF01708.11 KFX90423.1 - 2 7.9 3.7 5.6 6.5 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein Pkinase PF00069.20 KFX90428.1 - 1.3e-52 178.5 0.0 3e-52 177.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90428.1 - 2e-23 82.7 0.1 5.5e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX90428.1 - 0.00013 21.7 3.3 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX90428.1 - 0.0038 16.6 0.2 0.014 14.7 0.2 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KFX90428.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) SNF2_N PF00176.18 KFX90429.1 - 8.5e-69 231.6 0.0 1.3e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX90429.1 - 2.5e-15 56.0 0.0 8.7e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFX90429.1 - 1.1e-05 24.4 0.0 2.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFX90429.1 - 9.7e-05 22.2 0.2 0.00055 19.8 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX90429.1 - 0.016 14.6 0.0 0.49 9.8 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase UCH PF00443.24 KFX90433.1 - 2.7e-13 49.6 0.0 2.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 KFX90433.1 - 3.2e-12 45.8 0.0 6.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.1 KFX90433.1 - 1.7e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 KFX90433.1 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain Flocculin_t3 PF13928.1 KFX90436.1 - 0.016 15.3 9.5 0.016 15.3 6.6 3.2 1 1 2 3 3 3 0 Flocculin type 3 repeat Glyco_hydro_4 PF02056.11 KFX90436.1 - 0.019 14.3 0.4 0.026 13.8 0.3 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase DUF1138 PF06592.8 KFX90436.1 - 0.083 12.9 1.4 0.15 12.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) TP_methylase PF00590.15 KFX90438.1 - 4.4e-42 144.1 1.4 1.7e-41 142.2 0.2 2.4 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KFX90438.1 - 6.4e-10 39.2 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KFX90438.1 - 4.9e-09 35.3 0.0 1.7e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KFX90438.1 - 1.4e-06 27.1 0.3 4.4e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central WSC PF01822.14 KFX90439.1 - 9.2e-15 54.3 6.1 2.5e-14 52.9 4.2 1.8 1 0 0 1 1 1 1 WSC domain eIF-5_eIF-2B PF01873.12 KFX90442.1 - 4.6e-39 132.9 0.0 7.1e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KFX90442.1 - 1.1e-25 89.3 0.0 3.1e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1387 PF07139.6 KFX90442.1 - 0.0041 16.7 6.5 0.0078 15.8 4.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) HEAT_2 PF13646.1 KFX90443.1 - 5.7e-08 32.9 2.2 0.49 10.7 0.0 5.0 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KFX90443.1 - 5.8e-05 22.8 0.5 1.8 8.8 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.18 KFX90443.1 - 0.081 12.7 1.8 0.83 9.5 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SRPRB PF09439.5 KFX90444.1 - 1.1e-32 112.6 0.0 8.1e-32 109.8 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX90444.1 - 1.5e-07 30.8 0.0 5e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX90444.1 - 3.4e-07 29.8 0.0 1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX90444.1 - 3.4e-06 27.0 0.0 6.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFX90444.1 - 2.4e-05 24.3 0.5 0.00029 20.8 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain Arf PF00025.16 KFX90444.1 - 3.9e-05 22.9 0.0 0.0011 18.2 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 KFX90444.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX90444.1 - 0.0063 15.6 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.14 KFX90444.1 - 0.009 15.4 0.3 2.1 7.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KFX90444.1 - 0.014 15.1 0.1 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KFX90444.1 - 0.017 14.5 0.0 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 KFX90444.1 - 0.029 13.8 0.0 0.43 10.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KFX90444.1 - 0.035 13.6 0.2 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX90444.1 - 0.038 14.2 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Septin PF00735.13 KFX90444.1 - 0.04 12.9 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 KFX90444.1 - 0.043 12.9 0.2 0.25 10.5 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KFX90444.1 - 0.065 13.4 1.3 0.64 10.2 0.9 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 KFX90444.1 - 0.093 12.1 0.1 4.4 6.6 0.0 2.4 2 1 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 KFX90444.1 - 0.11 12.0 0.1 6.7 6.1 0.0 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 KFX90444.1 - 0.13 12.8 0.0 0.36 11.3 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein zf-DHHC PF01529.15 KFX90445.1 - 2.5e-38 131.2 8.5 2.5e-38 131.2 5.9 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.2 KFX90445.1 - 4.2e-32 110.3 0.0 1.2e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90445.1 - 1.1e-31 107.0 4.5 1.8e-09 36.9 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFX90445.1 - 6.7e-24 83.8 0.9 3.3e-06 27.4 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX90445.1 - 5.5e-23 80.4 2.3 5.3e-07 29.6 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX90445.1 - 5.9e-21 72.4 1.1 2.2e-08 33.5 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat DUF1401 PF07180.6 KFX90445.1 - 0.21 11.3 0.1 0.48 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) Kinesin PF00225.18 KFX90446.1 - 1.2e-109 366.1 1.0 2e-109 365.3 0.0 1.9 3 0 0 3 3 3 1 Kinesin motor domain DUF3694 PF12473.3 KFX90446.1 - 2.9e-39 133.9 0.1 6.6e-39 132.7 0.1 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KFX90446.1 - 1.3e-06 28.5 0.0 4e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 KFX90446.1 - 3.4e-06 26.9 0.6 8.3e-06 25.7 0.4 1.7 1 0 0 1 1 1 1 Kinesin protein 1B CaM_bdg_C0 PF10562.4 KFX90446.1 - 0.064 13.1 0.8 0.18 11.6 0.5 1.8 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DinI PF06183.8 KFX90446.1 - 0.1 12.6 5.4 0.45 10.5 3.7 2.1 1 0 0 1 1 1 0 DinI-like family IncA PF04156.9 KFX90446.1 - 5.6 6.5 17.7 2.9 7.4 7.1 2.7 2 0 0 2 2 2 0 IncA protein PALP PF00291.20 KFX90447.1 - 7.6e-61 205.9 0.2 9.9e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KFX90447.1 - 3e-10 39.7 0.0 5.5e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain Peptidase_M24 PF00557.19 KFX90448.1 - 9.1e-52 175.6 0.0 1.2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFX90448.1 - 8.4e-25 86.7 0.0 7.1e-24 83.7 0.0 2.4 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain Ribul_P_3_epim PF00834.14 KFX90453.1 - 1e-51 174.9 0.1 1e-50 171.6 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Glyco_trans_4_2 PF13477.1 KFX90453.1 - 0.079 12.7 0.0 0.8 9.5 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like QRPTase_C PF01729.14 KFX90453.1 - 0.085 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CBM_14 PF01607.19 KFX90454.1 - 1.7e-39 133.4 58.3 1.2e-09 37.9 5.8 6.8 5 1 2 7 7 7 6 Chitin binding Peritrophin-A domain ANATO PF01821.13 KFX90454.1 - 1.2 9.2 6.3 22 5.3 0.0 4.1 4 0 0 4 4 4 0 Anaphylotoxin-like domain Pkinase PF00069.20 KFX90455.1 - 5.1e-23 81.5 0.0 6.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90455.1 - 5.5e-20 71.5 0.0 8.2e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX90455.1 - 1.3e-05 24.2 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TrkH PF02386.11 KFX90456.1 - 9e-90 300.7 5.8 2.9e-84 282.6 1.0 2.1 2 0 0 2 2 2 2 Cation transport protein HA2 PF04408.18 KFX90461.1 - 5.3e-18 64.9 0.2 2.8e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFX90461.1 - 1.4e-14 53.8 0.0 3.5e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFX90461.1 - 4.4e-14 52.0 0.4 3.5e-13 49.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.17 KFX90461.1 - 8.4e-13 48.2 0.0 1.7e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 KFX90461.1 - 2.2e-09 37.0 0.1 4.3e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX90461.1 - 0.00014 22.0 0.2 0.00049 20.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KFX90461.1 - 0.00086 19.1 0.0 0.0038 17.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KFX90461.1 - 0.0031 16.9 0.2 0.016 14.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DND1_DSRM PF14709.1 KFX90461.1 - 0.0061 16.8 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 KFX90461.1 - 0.0085 15.0 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Aldo_ket_red PF00248.16 KFX90461.1 - 0.012 14.4 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 Aldo/keto reductase family AAA_23 PF13476.1 KFX90461.1 - 0.015 15.6 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFX90461.1 - 0.026 13.6 0.0 0.058 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KFX90461.1 - 0.055 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2533 PF10752.4 KFX90461.1 - 0.067 13.5 0.5 0.24 11.7 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) AAA_25 PF13481.1 KFX90461.1 - 0.077 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PQ-loop PF04193.9 KFX90463.1 - 8.4e-28 95.7 17.4 5.6e-15 54.6 0.9 2.8 3 0 0 3 3 3 2 PQ loop repeat GtrA PF04138.9 KFX90463.1 - 0.00077 19.4 1.2 0.0072 16.2 0.2 2.4 1 1 1 2 2 2 1 GtrA-like protein DUF3754 PF12576.3 KFX90463.1 - 0.12 11.9 0.2 0.28 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) DUF876 PF05936.7 KFX90463.1 - 0.16 10.3 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) Dynamin_N PF00350.18 KFX90464.1 - 1.5e-42 145.2 0.0 3.1e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFX90464.1 - 3.1e-12 45.9 0.1 4.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KFX90464.1 - 0.0022 17.9 0.0 0.0092 15.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX90464.1 - 0.0037 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KFX90464.1 - 0.026 14.4 1.7 0.39 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 KFX90464.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 KFX90465.1 - 2.2e-14 52.8 0.0 2.6e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFX90465.1 - 6.6e-09 35.8 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KFX90465.1 - 1.6e-06 27.1 0.0 0.0001 21.1 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Cation_efflux PF01545.16 KFX90466.1 - 1.6e-30 106.2 10.9 2.1e-30 105.8 7.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1418 PF07214.7 KFX90466.1 - 0.18 11.4 0.8 0.43 10.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) PHO4 PF01384.15 KFX90467.1 - 0.012 14.2 0.0 0.03 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphate transporter family DUF2370 PF10176.4 KFX90467.1 - 0.16 11.2 1.2 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2956 PF11169.3 KFX90467.1 - 4 7.4 5.2 5.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) PIG-Y PF15159.1 KFX90467.1 - 8.3 6.7 9.9 46 4.3 6.8 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Ebp2 PF05890.7 KFX90469.1 - 4.2e-90 301.7 19.5 4.2e-90 301.7 13.5 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 zf-rbx1 PF12678.2 KFX90471.1 - 1.4e-09 37.9 0.4 2.5e-09 37.0 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFX90471.1 - 1.6e-09 37.4 3.5 1.3e-08 34.5 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFX90471.1 - 2.3e-06 27.1 0.8 4e-06 26.3 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX90471.1 - 9.9e-06 25.1 2.1 2.3e-05 24.0 1.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX90471.1 - 2.5e-05 23.8 3.3 7.1e-05 22.3 2.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX90471.1 - 0.00012 22.0 2.2 0.00012 22.0 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 KFX90471.1 - 0.014 13.1 0.3 0.02 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 KFX90471.1 - 0.015 15.0 1.1 0.039 13.7 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFX90471.1 - 0.19 11.4 5.3 0.034 13.8 0.8 2.0 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 KFX90471.1 - 0.45 10.5 2.9 1.8 8.5 2.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain HSBP1 PF06825.7 KFX90472.1 - 8.9e-14 50.8 1.1 1.3e-13 50.3 0.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2379 PF09543.5 KFX90472.1 - 0.064 13.2 0.1 0.076 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DUF2884 PF11101.3 KFX90472.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Thioredoxin PF00085.15 KFX90473.1 - 1.6e-58 194.8 0.0 3.4e-29 100.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KFX90473.1 - 7.2e-21 74.6 4.5 1.6e-20 73.4 2.7 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KFX90473.1 - 5.9e-20 71.5 0.8 7.6e-11 42.2 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFX90473.1 - 2.4e-17 62.7 0.0 3.4e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KFX90473.1 - 3e-13 49.7 0.2 0.00016 21.6 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 KFX90473.1 - 9.2e-09 35.0 0.1 0.0035 17.0 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KFX90473.1 - 1.5e-06 27.8 2.9 0.013 15.0 0.0 2.7 2 1 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 KFX90473.1 - 3.5e-05 23.5 0.1 0.091 12.5 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_9 PF14595.1 KFX90473.1 - 0.00019 20.9 0.2 0.17 11.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.1 KFX90473.1 - 0.00027 20.4 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 F plasmid transfer operon protein HyaE PF07449.6 KFX90473.1 - 0.0015 18.3 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KFX90473.1 - 0.0038 17.2 3.8 7.2 6.5 0.1 3.9 3 1 1 4 4 4 1 Thioredoxin DDE_Tnp_1_2 PF13586.1 KFX90473.1 - 0.011 15.9 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Helicase_C_4 PF13871.1 KFX90473.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase_C-like DUF953 PF06110.6 KFX90473.1 - 0.17 11.3 1.6 0.64 9.4 0.1 2.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.15 KFX90473.1 - 0.7 9.4 5.7 6.4 6.2 0.1 3.4 3 1 1 4 4 4 0 DSBA-like thioredoxin domain MKT1_C PF12246.3 KFX90474.1 - 2.5e-55 187.1 0.0 3.9e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KFX90474.1 - 6e-26 90.6 0.1 1.6e-25 89.2 0.1 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KFX90474.1 - 0.018 15.1 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 XPG I-region XPG_N PF00752.12 KFX90474.1 - 0.099 12.9 0.0 0.49 10.6 0.0 2.3 1 0 0 1 1 1 0 XPG N-terminal domain DUF1882 PF08966.6 KFX90475.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) Pfg27 PF09216.5 KFX90475.1 - 0.059 12.9 0.7 0.15 11.6 0.6 1.5 2 0 0 2 2 2 0 Pfg27 DUF1632 PF07857.7 KFX90475.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 CEO family (DUF1632) AF1Q PF15017.1 KFX90475.1 - 0.68 9.8 6.5 1.9 8.4 4.5 1.7 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator TruB_N PF01509.13 KFX90476.1 - 8.2e-48 162.3 0.5 1.9e-47 161.1 0.3 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DUF1179 PF06678.6 KFX90476.1 - 2.5 8.4 4.9 4.3 7.6 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1179) Sec2p PF06428.6 KFX90477.1 - 8.8e-08 31.9 11.7 8.9e-08 31.9 5.3 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.4 KFX90477.1 - 0.0002 21.4 10.2 0.054 13.4 3.8 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 DUF444 PF04285.7 KFX90477.1 - 0.03 12.9 0.8 0.043 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Herpes_U30 PF04523.8 KFX90477.1 - 0.04 11.3 2.8 0.64 7.4 0.4 2.0 2 0 0 2 2 2 0 Herpes virus tegument protein U30 zf-RING_3 PF14369.1 KFX90477.1 - 0.074 13.0 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc-finger CpXC PF14353.1 KFX90477.1 - 0.24 11.3 1.1 0.81 9.6 0.0 2.1 2 0 0 2 2 2 0 CpXC protein SlyX PF04102.7 KFX90477.1 - 0.37 11.2 16.6 0.38 11.1 0.9 3.7 2 2 2 4 4 4 0 SlyX DUF883 PF05957.8 KFX90477.1 - 0.58 10.5 8.4 0.2 12.0 0.5 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.7 KFX90477.1 - 0.99 9.1 12.7 0.52 10.0 0.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Caudo_TAP PF02413.12 KFX90477.1 - 3.3 7.8 11.2 0.36 10.9 1.4 2.6 1 1 0 2 2 2 0 Caudovirales tail fibre assembly protein Myosin_tail_1 PF01576.14 KFX90477.1 - 3.5 5.2 20.3 2.8 5.5 0.7 2.2 2 0 0 2 2 2 0 Myosin tail DUF3584 PF12128.3 KFX90477.1 - 4 4.6 14.7 29 1.7 10.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.9 KFX90477.1 - 4.3 7.2 11.7 5.7 6.8 0.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KFX90477.1 - 4.8 6.7 18.4 3.6 7.1 1.0 2.1 1 1 1 2 2 2 0 IncA protein COG2 PF06148.6 KFX90477.1 - 5 6.9 6.9 14 5.6 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3373 PF11853.3 KFX90477.1 - 6.3 5.2 5.1 9.7 4.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Ribosomal_L32e PF01655.13 KFX90478.1 - 1.8e-29 101.9 0.2 3.4e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.26 KFX90478.1 - 4e-23 80.9 2.7 9.9e-23 79.6 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFX90478.1 - 2.8e-21 75.1 1.6 1.5e-19 69.6 0.0 3.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFX90478.1 - 5.6e-14 51.9 18.7 1e-13 51.0 13.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFX90478.1 - 0.0044 16.6 7.3 0.26 11.0 0.9 2.5 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KFX90478.1 - 4.5 7.6 9.3 0.32 11.3 2.8 1.9 2 0 0 2 2 2 0 Cytochrome c3 DUF1356 PF07092.7 KFX90478.1 - 7 5.7 6.5 11 5.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) tRNA-synt_1c PF00749.16 KFX90479.1 - 1.7e-89 299.6 0.0 2.2e-89 299.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Synthase_beta PF11421.3 KFX90479.1 - 0.21 12.2 6.1 0.6 10.8 4.2 1.8 1 0 0 1 1 1 0 ATP synthase F1 beta subunit JAB PF01398.16 KFX90480.1 - 1.5e-29 102.0 0.1 5.4e-29 100.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFX90480.1 - 6.6e-08 32.0 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 KFX90481.1 - 7.3e-76 256.0 9.4 1.1e-75 255.4 6.5 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) BLOC1_2 PF10046.4 KFX90481.1 - 3 8.0 8.2 1.3 9.2 0.1 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2205 PF10224.4 KFX90481.1 - 3.9 7.1 7.1 8.5 6.0 0.1 3.5 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) EF-hand_4 PF12763.2 KFX90482.1 - 0.0008 19.1 0.1 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFX90482.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFX90482.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 KFX90482.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DNA_ligase_A_M PF01068.16 KFX90484.1 - 4.8e-45 153.4 0.0 8.6e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFX90484.1 - 1.2e-36 126.1 0.0 2.4e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFX90484.1 - 2.1e-15 56.9 0.0 7.9e-15 55.0 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KFX90484.1 - 2.6e-07 30.7 0.1 3.7e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KFX90484.1 - 0.0088 15.7 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV UPRTase PF14681.1 KFX90485.1 - 8.4e-72 240.7 0.0 9.8e-72 240.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFX90485.1 - 9.9e-06 25.3 0.1 2.6e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 KFX90485.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain TMP-TENI PF02581.12 KFX90485.1 - 0.02 13.9 0.5 0.3 10.2 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI P5CR_dimer PF14748.1 KFX90485.1 - 0.046 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF2491 PF10679.4 KFX90487.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Abhydrolase_6 PF12697.2 KFX90488.1 - 0.00016 21.6 0.0 0.00047 20.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KFX90488.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KFX90488.1 - 0.2 10.9 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF390 PF04094.9 KFX90491.1 - 0.023 12.7 0.7 0.025 12.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) MRG PF05712.8 KFX90492.1 - 1e-49 168.0 0.0 1.6e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KFX90492.1 - 4.1e-08 32.8 1.5 9.4e-08 31.6 1.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KFX90492.1 - 0.0007 19.2 1.0 0.0019 17.8 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain eIF-6 PF01912.13 KFX90501.1 - 1.9e-82 275.1 1.2 2.7e-82 274.6 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 KFX90501.1 - 0.059 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage holin family 6 Swi5 PF07061.6 KFX90502.1 - 6.6e-26 89.9 1.0 9.5e-26 89.4 0.1 1.6 1 1 1 2 2 2 1 Swi5 DUF2203 PF09969.4 KFX90502.1 - 8.9e-05 22.6 1.1 0.00021 21.5 0.6 1.6 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2203) CENP-F_N PF10481.4 KFX90502.1 - 0.0017 17.7 1.1 0.0021 17.5 0.7 1.2 1 0 0 1 1 1 1 Cenp-F N-terminal domain DUF812 PF05667.6 KFX90502.1 - 0.011 14.3 6.0 0.012 14.1 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4570 PF15134.1 KFX90502.1 - 0.034 13.9 4.1 0.056 13.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF1110 PF06533.7 KFX90502.1 - 0.045 13.5 0.9 0.063 13.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) Tropomyosin_1 PF12718.2 KFX90502.1 - 0.054 13.3 10.5 0.039 13.7 6.1 1.4 1 1 0 1 1 1 0 Tropomyosin like BBS2_C PF14782.1 KFX90502.1 - 0.061 11.8 1.3 0.071 11.6 0.9 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal APG6 PF04111.7 KFX90502.1 - 0.14 11.1 2.6 0.17 10.9 1.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Herpes_UL6 PF01763.11 KFX90502.1 - 0.22 9.6 1.2 0.27 9.3 0.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc24 PF08286.6 KFX90502.1 - 0.33 10.6 2.6 0.53 9.9 1.8 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Phage_GP20 PF06810.6 KFX90502.1 - 0.34 10.3 5.8 0.47 9.8 4.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 KFX90502.1 - 0.36 9.9 7.1 0.49 9.5 4.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YdfA_immunity PF12127.3 KFX90502.1 - 0.45 9.3 3.9 0.56 9.0 2.7 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial Atg14 PF10186.4 KFX90502.1 - 0.68 8.8 6.2 0.9 8.4 4.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 KFX90502.1 - 0.97 8.3 6.0 1.1 8.1 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2681 PF10883.3 KFX90502.1 - 1.2 9.4 7.4 1.8 8.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Macoilin PF09726.4 KFX90502.1 - 1.2 7.3 7.7 1.4 7.0 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 KFX90502.1 - 2.2 7.6 17.1 2.3 7.4 11.8 1.1 1 0 0 1 1 1 0 Vta1 like OPA3 PF07047.7 KFX90502.1 - 2.7 7.7 8.0 4.2 7.1 5.6 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Seryl_tRNA_N PF02403.17 KFX90502.1 - 2.8 7.9 8.9 4.9 7.2 5.5 1.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Retinal PF15449.1 KFX90502.1 - 8.8 3.8 18.6 10 3.6 12.9 1.0 1 0 0 1 1 1 0 Retinal protein DivIC PF04977.10 KFX90502.1 - 8.9 5.8 10.0 6.6 6.3 5.7 1.7 2 0 0 2 2 2 0 Septum formation initiator adh_short_C2 PF13561.1 KFX90503.1 - 0.0004 20.2 0.0 0.00081 19.2 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX90503.1 - 0.0035 17.2 0.2 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase SurE PF01975.12 KFX90504.1 - 1.1e-42 145.6 0.0 1.7e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.10 KFX90504.1 - 1.8e-25 89.5 0.0 2.7e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KFX90504.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DASH_Duo1 PF08651.5 KFX90506.1 - 0.032 13.8 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 GASA PF02704.9 KFX90515.1 - 0.15 12.0 0.5 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Gibberellin regulated protein Aldolase_II PF00596.16 KFX90527.1 - 2.6e-43 147.7 0.1 3.6e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hemerythrin PF01814.18 KFX90528.1 - 1.6e-09 37.9 0.8 2.7e-09 37.3 0.5 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Transglut_core PF01841.14 KFX90529.1 - 3.8e-11 43.1 0.0 7.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KFX90529.1 - 0.002 17.3 0.0 0.018 14.3 0.0 2.3 2 1 0 2 2 2 1 Transglutaminase-like domain 2-Hacid_dh_C PF02826.14 KFX90535.1 - 1.9e-51 173.7 0.0 2.9e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX90535.1 - 9.3e-16 57.5 0.0 1.3e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX90535.1 - 0.0037 17.1 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase EF-hand_1 PF00036.27 KFX90541.1 - 1.7e-26 89.4 3.5 3.7e-06 25.8 0.0 5.5 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 KFX90541.1 - 4.3e-22 75.9 7.5 6.7e-05 22.4 0.1 5.5 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.1 KFX90541.1 - 1e-21 76.8 2.4 2.9e-08 33.7 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFX90541.1 - 6.1e-18 63.2 11.1 2.5e-05 23.4 0.3 5.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 KFX90541.1 - 1.3e-16 59.9 9.0 0.00012 21.5 0.0 5.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_2 PF09068.6 KFX90541.1 - 0.14 12.1 0.0 49 4.0 0.0 3.2 2 1 1 3 3 3 0 EF hand DUF131 PF01998.12 KFX90546.1 - 0.013 14.8 2.0 0.046 13.0 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF131 Cmc1 PF08583.5 KFX90554.1 - 1.8e-13 50.0 4.9 5.2e-13 48.5 3.4 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Utp11 PF03998.8 KFX90555.1 - 2.9e-56 191.0 24.1 3.3e-56 190.8 16.7 1.0 1 0 0 1 1 1 1 Utp11 protein Lipoprotein_20 PF13942.1 KFX90555.1 - 4.3 6.8 10.3 9.8 5.6 7.1 1.6 1 1 0 1 1 1 0 YfhG lipoprotein Nucleoside_tran PF01733.13 KFX90556.1 - 0.056 12.5 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter zf-HC5HC2H PF13771.1 KFX90560.1 - 0.005 16.9 2.9 0.0079 16.3 2.0 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFX90560.1 - 0.048 13.6 2.8 0.075 13.0 1.9 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Pput2613-deam PF14427.1 KFX90560.1 - 0.056 13.1 1.6 0.082 12.5 0.1 1.9 1 1 1 2 2 2 0 Pput_2613-like deaminase PHD PF00628.24 KFX90560.1 - 0.43 10.3 4.4 0.81 9.4 3.0 1.5 1 1 0 1 1 1 0 PHD-finger DEAD PF00270.24 KFX90561.1 - 9e-41 139.1 0.2 2.1e-40 137.9 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX90561.1 - 2.8e-29 100.8 0.2 5.6e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFX90561.1 - 0.0061 16.2 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain SecA_DEAD PF07517.9 KFX90561.1 - 0.0071 15.6 0.3 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 KFX90561.1 - 0.012 15.2 0.5 0.027 14.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KFX90561.1 - 0.027 14.2 0.1 0.067 13.0 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KFX90561.1 - 0.056 13.1 0.2 0.2 11.3 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KFX90561.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 KFX90561.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 KFX90561.1 - 0.16 12.0 0.6 0.74 9.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 KFX90571.1 - 1.2e-17 63.6 0.0 2.1e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX90571.1 - 1.7e-16 59.9 3.1 2.8e-16 59.2 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX90571.1 - 1.6e-05 25.7 0.0 3.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX90571.1 - 0.0063 15.6 0.3 0.01 15.0 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX90571.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Molydop_binding PF01568.16 KFX90571.1 - 0.16 11.7 0.1 1 9.2 0.0 2.2 3 0 0 3 3 3 0 Molydopterin dinucleotide binding domain Peptidase_M1 PF01433.15 KFX90572.1 - 6.9e-132 440.2 0.5 6.9e-132 440.2 0.3 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 KFX90572.1 - 6.7e-72 242.4 2.4 1.9e-71 240.9 0.9 2.1 2 1 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFX90572.1 - 2.1e-22 79.5 2.2 5.5e-22 78.1 0.3 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KFX90572.1 - 0.12 12.1 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF1570 PF07607.6 KFX90572.1 - 0.37 10.8 4.9 12 5.8 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1570) CBFD_NFYB_HMF PF00808.18 KFX90573.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 KFX90573.1 - 0.029 14.3 0.4 0.09 12.7 0.3 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W DUF2617 PF10936.3 KFX90574.1 - 0.026 14.0 0.9 0.051 13.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2617 DUF4404 PF14357.1 KFX90574.1 - 0.21 12.0 5.8 0.91 9.9 4.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DctQ PF04290.7 KFX90578.1 - 0.0074 16.0 2.1 0.0074 16.0 1.4 2.3 3 0 0 3 3 3 1 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_1 PF04531.8 KFX90578.1 - 1.7 8.7 6.0 0.56 10.3 2.0 1.7 2 0 0 2 2 2 0 Bacteriophage holin DUF2975 PF11188.3 KFX90578.1 - 2.4 7.8 9.8 3.8 7.2 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) LRR_4 PF12799.2 KFX90579.1 - 4.8e-31 105.8 29.2 5e-06 25.9 2.2 8.4 7 1 0 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX90579.1 - 1.6e-26 91.8 33.9 1.3e-07 31.2 2.5 7.4 4 2 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KFX90579.1 - 1.8e-09 36.3 36.0 0.2 11.8 0.3 12.4 12 2 2 14 14 14 5 Leucine Rich Repeat LRR_9 PF14580.1 KFX90579.1 - 3.9e-08 33.0 8.7 8.6e-05 22.1 0.5 3.7 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KFX90579.1 - 0.00012 21.7 45.5 0.3 11.4 0.2 11.7 13 0 0 13 13 13 4 Leucine rich repeat LRR_6 PF13516.1 KFX90579.1 - 0.014 15.3 38.6 0.032 14.2 0.4 10.2 10 2 1 11 11 11 0 Leucine Rich repeat Tubulin PF00091.20 KFX90580.1 - 2.9e-66 223.3 0.0 3.9e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX90580.1 - 2.4e-45 153.6 0.0 3.8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFX90580.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tim17 PF02466.14 KFX90581.1 - 8.1e-26 90.5 1.9 1.2e-25 90.0 1.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.13 KFX90582.1 - 8.1e-38 130.0 0.1 1.1e-37 129.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain Sugar_tr PF00083.19 KFX90584.1 - 1.8e-77 260.8 27.6 2.1e-77 260.6 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90584.1 - 1.1e-30 106.5 26.9 1.1e-26 93.4 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX90584.1 - 4.2e-05 21.9 2.4 7.5e-05 21.1 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2781 PF10914.3 KFX90584.1 - 0.011 15.4 0.5 0.011 15.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) CoA_binding_3 PF13727.1 KFX90585.1 - 0.093 12.5 3.1 0.13 12.0 2.2 1.2 1 0 0 1 1 1 0 CoA-binding domain CopD PF05425.8 KFX90585.1 - 2.5 8.3 12.3 3.2 7.9 7.7 1.9 1 1 0 1 1 1 0 Copper resistance protein D DUF2374 PF09574.5 KFX90585.1 - 3.1 7.5 6.8 3.1 7.4 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) TPR_14 PF13428.1 KFX90591.1 - 4.5e-32 107.6 24.7 0.0013 19.1 0.1 13.0 4 3 10 14 14 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFX90591.1 - 7.2e-23 80.6 15.2 1e-05 26.0 0.3 7.8 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90591.1 - 2e-22 79.2 20.8 3.9e-07 30.3 0.2 9.4 5 3 3 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFX90591.1 - 4.4e-14 51.8 10.1 0.00058 19.4 0.0 7.9 6 3 4 10 10 10 5 TPR repeat PRP1_N PF06424.7 KFX90591.1 - 7.4e-14 52.2 0.0 2.3e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.12 KFX90591.1 - 2.2e-12 45.9 11.5 0.19 11.7 0.0 9.7 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFX90591.1 - 1.3e-07 30.9 18.3 1.2e-05 24.5 2.5 5.9 2 2 4 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX90591.1 - 2.3e-07 30.1 0.0 0.45 10.2 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX90591.1 - 5.5e-07 29.2 6.4 7.3 7.0 0.0 8.8 9 1 0 9 9 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX90591.1 - 2e-06 27.1 0.1 2.9 7.8 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX90591.1 - 2.5e-06 27.5 4.5 32 5.2 0.0 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.3 KFX90591.1 - 3.3e-05 22.8 2.6 0.034 12.9 0.0 4.6 3 1 2 6 6 6 1 NMDA receptor-regulated protein 1 Suf PF05843.9 KFX90591.1 - 3.3e-05 23.7 0.1 0.83 9.3 0.0 4.5 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_9 PF13371.1 KFX90591.1 - 0.00015 21.5 3.2 1.7 8.5 0.0 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX90591.1 - 0.00045 20.1 3.9 1.5 8.8 0.0 5.8 5 2 0 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.4 KFX90591.1 - 0.0018 16.9 0.6 1.8 7.0 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) Apc3 PF12895.2 KFX90591.1 - 0.0061 16.6 0.0 0.6 10.2 0.0 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 KFX90591.1 - 0.019 14.9 15.9 0.023 14.6 0.6 4.3 4 1 0 5 5 5 0 Tetratricopeptide repeat FAT PF02259.18 KFX90591.1 - 0.02 13.8 4.8 3.5 6.5 0.6 3.6 2 1 1 3 3 3 0 FAT domain DUF4396 PF14342.1 KFX90592.1 - 3.6e-34 117.8 1.9 4e-34 117.7 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Phage_holin_2 PF04550.7 KFX90592.1 - 0.36 10.9 2.1 1.8 8.7 0.1 2.5 1 1 1 2 2 2 0 Phage holin family 2 DUF1025 PF06262.6 KFX90593.1 - 0.036 13.8 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Possibl zinc metallo-peptidase DUF2422 PF10337.4 KFX90595.1 - 1.2e-95 321.0 6.6 9.5e-95 318.0 3.8 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KFX90595.1 - 1.1e-15 57.7 19.0 1.1e-15 57.7 13.2 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KFX90595.1 - 3.9e-06 26.6 0.0 0.00058 19.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KFX90595.1 - 0.018 13.7 6.1 0.071 11.7 4.0 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Ank_2 PF12796.2 KFX90596.1 - 6.5e-70 231.5 12.1 4.4e-17 62.2 0.1 5.6 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90596.1 - 9e-54 176.7 33.2 3e-06 26.7 0.0 12.7 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KFX90596.1 - 8.7e-46 153.5 15.0 1.5e-07 31.7 0.1 9.1 3 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX90596.1 - 1.3e-42 139.5 10.1 0.0019 18.2 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 KFX90596.1 - 1.1e-29 101.7 19.8 5.3e-05 23.3 0.1 10.5 2 2 7 10 10 10 8 Ankyrin repeats (many copies) NACHT PF05729.7 KFX90596.1 - 3.7e-05 23.4 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 KFX90596.1 - 0.00012 21.5 0.0 0.00055 19.2 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) AAA_30 PF13604.1 KFX90596.1 - 0.0014 18.2 0.4 0.0068 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX90596.1 - 0.0016 18.6 0.0 0.0049 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX90596.1 - 0.0069 17.1 0.0 0.029 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX90596.1 - 0.011 15.6 0.0 0.049 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 KFX90596.1 - 0.026 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX90596.1 - 0.032 14.3 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DAP3 PF10236.4 KFX90596.1 - 0.076 11.9 0.0 0.23 10.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 KFX90596.1 - 0.085 11.7 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 KFX90596.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 NTPase Dendrin PF15498.1 KFX90596.1 - 0.45 8.9 0.4 2.3 6.6 0.0 1.9 2 0 0 2 2 2 0 Nephrin and CD2AP-binding protein, Dendrin FAD_binding_8 PF08022.7 KFX90597.1 - 2.7e-22 78.6 0.0 5.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX90597.1 - 8.4e-21 74.4 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFX90597.1 - 1.2e-16 60.9 8.7 1.2e-16 60.9 6.0 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFX90597.1 - 6.8e-06 26.1 0.0 2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain F-box-like PF12937.2 KFX90598.1 - 0.048 13.4 0.6 0.51 10.0 0.4 2.2 1 1 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 KFX90598.1 - 0.085 12.5 0.7 0.53 10.0 0.5 2.2 1 1 0 1 1 1 0 F-box-like domain DUF123 PF01986.11 KFX90603.1 - 0.0083 16.2 0.1 0.061 13.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF123 ELFV_dehydrog PF00208.16 KFX90609.1 - 9.7e-87 290.5 2.6 1.2e-86 290.2 1.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFX90609.1 - 2.6e-46 156.4 0.0 1.4e-45 154.0 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KFX90609.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 KFX90612.1 - 4.6e-16 58.4 1.2 8.3e-16 57.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90612.1 - 1.1e-07 31.5 11.5 1.9e-07 30.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX90613.1 - 1e-33 116.5 74.0 6.9e-29 100.6 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX90613.1 - 0.0056 16.4 15.2 0.053 13.3 0.4 3.6 4 0 0 4 4 4 2 MFS_1 like family DUF2855 PF11017.3 KFX90614.1 - 5.4e-50 170.3 0.0 6.3e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) tRNA-synt_1g PF09334.6 KFX90614.1 - 0.12 11.0 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) Acyl-CoA_dh_1 PF00441.19 KFX90615.1 - 2.1e-32 112.3 0.9 3.1e-32 111.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX90615.1 - 2.7e-20 71.6 0.3 4.8e-20 70.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX90615.1 - 5.8e-13 49.4 0.1 8.4e-12 45.6 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFX90615.1 - 1.4e-05 25.3 0.1 3.4e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.17 KFX90616.1 - 9e-28 96.6 0.0 1.6e-27 95.8 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFX90616.1 - 1.3e-07 32.1 0.0 1.6e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 KFX90616.1 - 0.0077 15.5 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Acetyltransf_7 PF13508.1 KFX90617.1 - 4.2e-07 30.0 0.0 1.5e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX90617.1 - 4.4e-07 29.8 0.0 8.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX90617.1 - 0.00048 20.2 0.0 0.0033 17.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX90617.1 - 0.0008 19.2 0.0 0.0041 16.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX90617.1 - 0.00093 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KFX90617.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CTP_transf_2 PF01467.21 KFX90619.1 - 0.0076 16.3 1.4 0.14 12.1 0.5 2.8 2 1 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 KFX90619.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase Utp12 PF04003.7 KFX90628.1 - 1.6e-07 31.2 0.0 2.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.5 KFX90628.1 - 0.013 14.5 20.5 0.015 14.4 14.2 1.1 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.20 KFX90629.1 - 1.1e-17 64.1 0.0 1.5e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90629.1 - 4e-07 29.3 0.0 1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Arginase PF00491.16 KFX90631.1 - 2.2e-43 148.5 0.1 2.6e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.3 KFX90632.1 - 2.3e-37 128.5 2.8 3e-37 128.1 1.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90632.1 - 0.011 15.6 13.0 0.031 14.1 9.0 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acatn PF13000.2 KFX90633.1 - 1.7e-138 462.5 24.5 9.8e-79 265.3 6.4 3.2 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.11 KFX90633.1 - 1.3e-28 99.7 65.1 2e-23 82.7 17.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 KFX90634.1 - 2.2e-28 98.1 0.2 5.2e-28 96.9 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX90634.1 - 4.3e-11 42.4 3.2 8.3e-11 41.5 2.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 KFX90634.1 - 7.3e-05 21.4 0.5 0.00011 20.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 KFX90634.1 - 0.00034 20.3 0.7 0.00047 19.8 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 KFX90634.1 - 0.0007 18.6 2.9 0.002 17.1 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KFX90634.1 - 0.00071 19.1 0.8 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFX90634.1 - 0.0015 17.4 2.4 0.0015 17.4 1.7 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFX90634.1 - 0.0018 18.2 2.0 0.0019 18.1 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 KFX90634.1 - 0.0025 17.2 0.1 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX90634.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KFX90634.1 - 0.0093 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 KFX90634.1 - 0.02 15.3 0.2 0.054 13.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX90634.1 - 0.02 14.3 0.1 0.037 13.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KFX90634.1 - 0.036 13.7 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 KFX90634.1 - 0.04 13.7 1.5 0.21 11.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 KFX90634.1 - 0.042 14.4 0.1 0.073 13.6 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain GIDA PF01134.17 KFX90634.1 - 0.31 9.8 2.9 0.47 9.2 2.0 1.3 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KFX90634.1 - 0.4 9.7 3.9 2.2 7.3 0.1 2.2 2 0 0 2 2 2 0 Thi4 family DUF647 PF04884.9 KFX90638.1 - 5.2e-84 281.3 0.4 6.1e-84 281.1 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PRELI PF04707.9 KFX90639.1 - 9.6e-44 148.7 0.6 1.1e-43 148.5 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family AhpC-TSA PF00578.16 KFX90640.1 - 4.8e-25 87.6 0.0 1e-24 86.6 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KFX90640.1 - 3.7e-16 58.9 0.0 6.1e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KFX90640.1 - 0.00043 20.1 0.0 0.0025 17.7 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Cpn10 PF00166.16 KFX90641.1 - 1.8e-24 85.4 0.0 3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Chitin_bind_1 PF00187.14 KFX90641.1 - 9.2e-06 25.5 17.6 1.4e-05 24.9 11.8 1.7 1 1 0 1 1 1 1 Chitin recognition protein RNase_P_Rpp14 PF01900.14 KFX90642.1 - 1.5e-35 121.3 0.0 2.6e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 KFX90643.1 - 1.3e-72 244.1 0.6 1.5e-72 243.9 0.0 1.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFX90643.1 - 0.0015 17.3 0.0 0.003 16.3 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KFX90643.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 KFX90643.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KFX90643.1 - 0.036 13.5 0.1 0.11 11.8 0.0 1.8 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 KFX90643.1 - 0.038 13.5 0.8 0.11 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX90643.1 - 0.042 14.6 6.2 0.11 13.3 0.6 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFX90643.1 - 0.1 11.6 0.2 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin MoCF_biosynth PF00994.19 KFX90644.1 - 1.7e-55 186.3 0.2 2.2e-28 98.5 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KFX90644.1 - 8.7e-33 112.9 1.1 1.5e-32 112.2 0.8 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KFX90644.1 - 3.4e-15 55.7 1.3 8.2e-15 54.5 0.1 2.4 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) WD40 PF00400.27 KFX90644.1 - 7.4e-14 51.0 4.3 0.0019 18.0 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Voltage_CLC PF00654.15 KFX90645.1 - 1.2e-88 297.5 25.9 1.2e-88 297.5 18.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFX90645.1 - 8.8e-14 51.0 0.1 1.3e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.20 KFX90646.1 - 3e-55 187.2 0.0 3.8e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90646.1 - 4.7e-19 68.4 0.0 1.9e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX90646.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C3HC PF07967.8 KFX90655.1 - 1.7e-31 108.7 0.0 4e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 C3HC zinc finger-like Rsm1 PF08600.5 KFX90655.1 - 9.3e-14 51.0 2.1 1.8e-11 43.7 0.0 2.9 2 1 0 2 2 2 2 Rsm1-like BIR PF00653.16 KFX90655.1 - 0.0029 18.0 0.1 0.051 14.0 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain Inositol_P PF00459.20 KFX90656.1 - 2.1e-53 181.3 2.1 3.6e-53 180.6 1.5 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 KFX90657.1 - 3.1e-24 85.2 0.0 3.6e-13 49.8 0.0 3.0 2 1 0 2 2 2 2 Ribosomal protein L6 ATG16 PF08614.6 KFX90658.1 - 0.0042 16.9 3.4 0.0042 16.9 2.4 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) IL34 PF15036.1 KFX90658.1 - 0.028 14.0 0.0 0.095 12.2 0.0 1.8 1 1 1 2 2 2 0 Interleukin 34 MitMem_reg PF13012.1 KFX90658.1 - 0.22 11.6 5.2 0.81 9.7 2.6 2.4 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function CtIP_N PF10482.4 KFX90658.1 - 0.22 11.3 0.1 0.22 11.3 0.0 2.3 4 0 0 4 4 4 0 Tumour-suppressor protein CtIP N-terminal domain NPV_P10 PF05531.7 KFX90658.1 - 0.43 10.8 4.6 9.6 6.5 0.1 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 KFX90658.1 - 0.51 8.7 6.7 0.72 8.2 4.7 1.1 1 0 0 1 1 1 0 AAA domain DUF3510 PF12022.3 KFX90658.1 - 1.2 9.2 6.0 10 6.2 0.8 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) Syntaxin-6_N PF09177.6 KFX90658.1 - 1.3 9.5 5.1 6.4 7.2 0.4 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 KFX90658.1 - 2.4 7.2 12.0 0.21 10.7 0.8 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein TMCO5 PF14992.1 KFX90658.1 - 6.5 5.7 8.9 9.4 5.2 1.4 2.1 1 1 0 2 2 2 0 TMCO5 family BRO1 PF03097.13 KFX90662.1 - 8e-102 340.7 0.0 9.2e-102 340.5 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain BCDHK_Adom3 PF10436.4 KFX90663.1 - 1.2e-68 229.8 0.0 4.3e-68 227.9 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFX90663.1 - 5e-18 64.8 0.0 6.8e-17 61.1 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFX90663.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 KFX90663.1 - 0.063 12.6 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Sorbin homologous domain Ribosomal_L22 PF00237.14 KFX90663.1 - 0.11 12.5 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e DUF2415 PF10313.4 KFX90665.1 - 5.1e-13 48.4 0.0 9.7e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) HSP70 PF00012.15 KFX90666.1 - 6.4e-263 873.1 15.2 7.3e-263 872.9 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFX90666.1 - 7.7e-15 54.3 4.7 1.3e-12 47.0 1.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KFX90666.1 - 0.00014 21.4 0.1 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFX90666.1 - 0.0012 18.6 6.2 1.9 8.3 0.5 4.3 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 KFX90666.1 - 0.0093 15.0 1.5 1.2 8.2 0.0 3.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase StbA PF06406.6 KFX90666.1 - 0.035 13.0 4.4 0.12 11.2 0.0 2.8 3 1 1 4 4 4 0 StbA protein DUF615 PF04751.9 KFX90666.1 - 0.12 12.0 4.4 0.1 12.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DnaG_DnaB_bind PF08278.6 KFX90666.1 - 0.12 12.5 2.6 0.43 10.7 1.8 1.9 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF4363 PF14276.1 KFX90666.1 - 0.14 11.9 3.3 0.25 11.0 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) eIF3g PF12353.3 KFX90667.1 - 1e-46 158.0 6.7 1.7e-46 157.3 4.7 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KFX90667.1 - 4.6e-17 61.4 0.1 7.7e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX90667.1 - 5.8e-12 45.4 0.1 1e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX90667.1 - 1e-05 25.2 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.28 KFX90669.1 - 0.0069 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain SUR7 PF06687.7 KFX90670.1 - 8.1e-32 110.5 1.8 8.9e-32 110.3 1.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KFX90670.1 - 0.0055 16.6 3.9 0.0081 16.0 2.7 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF4013 PF13197.1 KFX90670.1 - 1.1 8.5 15.3 2.3 7.5 10.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) FAD_binding_3 PF01494.14 KFX90683.1 - 2.4e-14 53.1 0.0 3.2e-06 26.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFX90683.1 - 2.2e-05 24.3 0.0 5.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX90683.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX90683.1 - 0.0033 16.3 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KFX90683.1 - 0.0057 15.5 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KFX90683.1 - 0.013 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX90683.1 - 0.023 15.0 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFX90683.1 - 0.083 12.8 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain A2M_N_2 PF07703.9 KFX90683.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region Lycopene_cycl PF05834.7 KFX90683.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Beta-lactamase PF00144.19 KFX90684.1 - 1.8e-43 148.8 0.0 2.4e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Phage_Treg PF04761.7 KFX90684.1 - 0.065 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Peptidase_S11 PF00768.15 KFX90684.1 - 0.12 11.5 0.0 1.5 7.9 0.0 2.4 2 1 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase AflR PF08493.5 KFX90686.1 - 3.4e-07 29.5 0.2 4.4e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Aflatoxin regulatory protein PEP_mutase PF13714.1 KFX90687.1 - 7.5e-42 143.1 0.2 9.2e-42 142.8 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFX90687.1 - 2.2e-18 65.7 0.3 3.2e-18 65.2 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MFS_1 PF07690.11 KFX90688.1 - 7.4e-23 80.8 41.4 2.2e-22 79.2 28.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily HSP70 PF00012.15 KFX90689.1 - 8.2e-169 562.3 2.7 8.2e-169 562.3 1.9 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KFX90689.1 - 1.4e-12 46.9 0.2 7.9e-12 44.4 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFX90689.1 - 8.7e-05 22.3 0.8 0.17 11.7 0.0 3.8 3 1 0 3 3 3 2 Cell division protein FtsA zf-BED PF02892.10 KFX90690.1 - 0.0016 18.1 0.2 0.0016 18.1 0.1 2.3 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 KFX90690.1 - 0.02 14.7 8.2 0.045 13.6 5.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 KFX90690.1 - 0.096 12.6 0.3 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Spc97_Spc98 PF04130.8 KFX90691.1 - 0.0003 19.2 0.0 0.00035 19.0 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Carn_acyltransf PF00755.15 KFX90692.1 - 2.1e-173 577.6 0.0 2.5e-173 577.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Eaf7 PF07904.8 KFX90692.1 - 6.9e-27 93.2 0.1 1.4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Ank_2 PF12796.2 KFX90693.1 - 2.1e-16 60.0 1.2 1.3e-08 35.0 0.0 6.5 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90693.1 - 5.1e-08 32.3 0.1 0.00081 19.0 0.0 6.4 7 1 0 7 7 7 1 Ankyrin repeat Ank_3 PF13606.1 KFX90693.1 - 1.7e-06 27.7 0.3 0.037 14.2 0.0 7.4 8 0 0 8 8 8 1 Ankyrin repeat NACHT PF05729.7 KFX90693.1 - 2e-06 27.6 0.0 7.3e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX90693.1 - 9.5e-06 25.7 0.1 8.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 KFX90693.1 - 8.7e-05 22.9 0.1 0.0084 16.5 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX90693.1 - 0.00084 19.5 0.1 8 6.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) NB-ARC PF00931.17 KFX90693.1 - 0.0055 15.5 0.0 0.016 14.1 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Vps52 PF04129.7 KFX90694.1 - 6e-120 401.1 0.9 8.2e-120 400.7 0.6 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KFX90694.1 - 0.00087 17.5 1.3 0.0019 16.4 0.9 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 KFX90694.1 - 0.058 13.2 0.1 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 KFX90694.1 - 0.084 12.5 0.1 0.27 10.8 0.1 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ubiquitin PF00240.18 KFX90695.1 - 6.4e-34 115.1 1.1 4.3e-33 112.5 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.12 KFX90695.1 - 3.6e-29 100.1 9.8 7.5e-29 99.0 6.8 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KFX90695.1 - 8.1e-19 67.0 0.7 1.7e-18 66.0 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like eIF-5a PF01287.15 KFX90695.1 - 4.2e-13 49.0 0.8 1e-12 47.7 0.5 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Ubiquitin_2 PF14560.1 KFX90695.1 - 0.00017 21.7 0.2 0.00056 20.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFX90695.1 - 0.0016 18.1 0.0 0.0042 16.7 0.0 1.7 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KFX90695.1 - 0.053 13.7 0.1 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain EFP_N PF08207.7 KFX90695.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain RabGAP-TBC PF00566.13 KFX90696.1 - 3.4e-25 88.7 0.1 5.4e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain M60-like PF13402.1 KFX90696.1 - 0.016 14.1 0.2 0.033 13.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase M60-like family MMS1_N PF10433.4 KFX90697.1 - 1.1e-77 261.3 0.0 2.1e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 KFX90698.1 - 3.5e-31 108.0 0.0 3.5e-31 108.0 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFX90698.1 - 5.4e-18 64.8 0.0 1.4e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFX90698.1 - 1.8e-09 37.5 2.5 3e-07 30.4 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX90698.1 - 4.2e-06 26.6 0.1 1.5e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFX90698.1 - 0.0026 17.3 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KFX90698.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain EthD PF07110.6 KFX90699.1 - 1.3e-21 77.2 0.0 2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 EthD domain His_Phos_2 PF00328.17 KFX90707.1 - 2.9e-48 164.9 0.0 3.4e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rot1 PF10681.4 KFX90708.1 - 4.7e-06 26.1 0.0 6.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF367 PF04034.8 KFX90717.1 - 1.4e-46 157.2 0.0 1.9e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) Neisseria_TspB PF05616.8 KFX90717.1 - 0.052 11.9 2.5 0.48 8.7 1.1 2.0 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein ProSAAS PF07259.7 KFX90717.1 - 1.1 8.6 7.0 0.94 8.9 3.7 1.5 1 1 0 1 1 1 0 ProSAAS precursor Defensin_2 PF01097.13 KFX90718.1 - 0.001 18.7 9.4 0.003 17.2 6.5 1.9 1 0 0 1 1 1 1 Arthropod defensin APH PF01636.18 KFX90719.1 - 7.6e-08 32.3 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX90719.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Prok-RING_1 PF14446.1 KFX90720.1 - 0.0043 16.7 6.1 0.01 15.5 4.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFX90720.1 - 0.0057 16.2 5.4 0.0098 15.4 3.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE PF01363.16 KFX90720.1 - 0.01 15.7 5.6 0.014 15.2 3.9 1.4 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_2 PF14445.1 KFX90720.1 - 0.065 13.1 2.8 0.13 12.2 1.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 FYVE_2 PF02318.11 KFX90720.1 - 0.076 12.9 2.9 0.13 12.1 2.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Baculo_IE-1 PF05290.6 KFX90720.1 - 0.48 10.1 4.3 0.39 10.4 2.2 1.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) DNA_RNApol_7kD PF03604.8 KFX90720.1 - 1 8.9 8.1 3.9 7.0 5.5 2.1 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 KFX90720.1 - 2 8.1 6.3 2.3 7.9 2.8 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family IBR PF01485.16 KFX90720.1 - 3.1 7.7 8.9 2.2 8.2 4.2 2.1 2 1 0 2 2 2 0 IBR domain zf-B_box PF00643.19 KFX90720.1 - 4.7 7.1 11.3 2.1 8.3 5.9 1.9 2 1 0 2 2 2 0 B-box zinc finger Acyl-CoA_dh_1 PF00441.19 KFX90721.1 - 2e-38 131.8 0.3 2e-38 131.8 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX90721.1 - 7e-21 73.4 0.1 1.6e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX90721.1 - 3.2e-17 63.1 0.0 9.7e-17 61.5 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 KFX90721.1 - 3.5e-17 61.9 0.2 6.2e-17 61.1 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KFX90721.1 - 2.6e-06 27.7 0.0 6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lipase_GDSL_2 PF13472.1 KFX90722.1 - 4.7e-20 72.4 0.1 5.7e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX90722.1 - 8.7e-16 58.4 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ras PF00071.17 KFX90723.1 - 3.6e-36 123.9 0.0 2e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFX90723.1 - 9.3e-10 39.0 0.0 2.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX90723.1 - 0.00022 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KFX90723.1 - 0.0014 17.9 0.0 0.0056 15.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX90723.1 - 0.018 14.4 1.2 0.49 9.7 0.1 3.2 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KFX90723.1 - 0.14 11.4 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain PUF PF00806.14 KFX90724.1 - 6.8e-13 47.3 0.0 0.03 13.7 0.0 7.5 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat MFS_1 PF07690.11 KFX90726.1 - 5.8e-18 64.7 42.1 1.3e-13 50.4 16.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX90726.1 - 8.1e-17 60.9 7.9 8.1e-17 60.9 5.5 2.5 2 2 0 2 2 2 2 Sugar (and other) transporter CN_hydrolase PF00795.17 KFX90727.1 - 3.7e-14 52.5 0.0 7.7e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SnoaL PF07366.7 KFX90728.1 - 3.3e-21 75.1 0.0 5.2e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KFX90728.1 - 1.8e-13 50.7 0.0 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain Alpha-amylase PF00128.19 KFX90729.1 - 3.7e-100 335.3 0.1 3.7e-100 335.3 0.1 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFX90729.1 - 0.00098 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KFX90729.1 - 0.0064 16.6 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Fungal_trans_2 PF11951.3 KFX90730.1 - 1.4e-51 175.2 4.9 2.1e-51 174.7 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90730.1 - 2.3e-07 30.5 9.5 4.5e-07 29.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_7 PF12973.2 KFX90731.1 - 2.4e-11 43.3 0.1 3.4e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.1 KFX90731.1 - 0.073 11.9 0.3 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Cupin_2 PF07883.6 KFX90731.1 - 0.28 10.7 3.2 0.37 10.3 1.4 1.8 1 1 1 2 2 2 0 Cupin domain Aminotran_3 PF00202.16 KFX90732.1 - 4.3e-85 285.5 0.0 5.3e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Methyltransf_23 PF13489.1 KFX90733.1 - 1.1e-15 57.7 0.0 2.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90733.1 - 8.2e-09 35.2 0.0 7.2e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX90733.1 - 1.1e-06 29.0 0.0 2.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX90733.1 - 2e-06 28.3 0.0 1.9e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain DUF1399 PF07173.7 KFX90733.1 - 0.0011 19.2 0.0 0.047 13.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) Methyltransf_12 PF08242.7 KFX90733.1 - 0.0022 18.4 0.0 0.018 15.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX90733.1 - 0.0036 16.7 0.0 0.0078 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFX90733.1 - 0.004 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX90733.1 - 0.0049 15.9 0.0 0.028 13.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KFX90733.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PmbA_TldD PF01523.11 KFX90733.1 - 0.049 12.8 0.2 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase PCMT PF01135.14 KFX90733.1 - 0.14 11.7 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRKCSH PF07915.8 KFX90739.1 - 2.3e-12 47.5 2.3 3.2e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pirin PF02678.11 KFX90740.1 - 5.3e-32 109.8 0.0 1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KFX90740.1 - 1.4e-23 82.9 0.0 2e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KFX90740.1 - 1.1e-06 28.0 1.6 0.00029 20.2 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFX90740.1 - 0.0027 17.0 0.5 0.44 9.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) TRAM_LAG1_CLN8 PF03798.11 KFX90741.1 - 1.3e-44 152.1 7.5 1.6e-44 151.8 5.2 1.0 1 0 0 1 1 1 1 TLC domain Dor1 PF04124.7 KFX90742.1 - 2.1e-53 180.9 0.9 1.6e-42 145.1 1.9 2.1 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 KFX90742.1 - 0.094 12.5 0.7 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Vps51/Vps67 YjcZ PF13990.1 KFX90742.1 - 0.12 11.4 4.7 1.4 7.9 0.6 2.8 3 0 0 3 3 3 0 YjcZ-like protein Cellulase-like PF12876.2 KFX90742.1 - 0.16 12.4 3.4 0.85 10.1 0.0 3.3 4 0 0 4 4 4 0 Sugar-binding cellulase-like ATP_transf PF09830.4 KFX90743.1 - 4.7e-16 58.3 0.0 8.2e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF829 PF05705.9 KFX90744.1 - 1.9e-51 175.1 0.1 2.2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ADH_N PF08240.7 KFX90745.1 - 3.8e-26 90.9 2.6 5.8e-26 90.3 1.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX90745.1 - 1.1e-12 47.6 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX90745.1 - 0.0034 16.5 0.1 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1273 PF06908.6 KFX90745.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DUF4489 PF14879.1 KFX90745.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) Lipase_GDSL_2 PF13472.1 KFX90746.1 - 1.2e-06 28.7 1.1 2.6e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX90746.1 - 8.6e-05 22.4 5.1 0.0012 18.6 3.5 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFX90746.1 - 0.13 11.9 0.0 20 4.8 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family PRP1_N PF06424.7 KFX90750.1 - 0.015 15.5 10.9 0.015 15.5 7.6 1.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Nucleo_P87 PF07267.6 KFX90750.1 - 0.056 12.1 13.1 0.098 11.3 9.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 KFX90750.1 - 0.071 12.6 5.7 0.13 11.7 4.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin RNase_H2-Ydr279 PF09468.5 KFX90750.1 - 0.17 11.0 3.4 0.3 10.2 2.4 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PBP1_TM PF14812.1 KFX90750.1 - 9.5 6.6 17.8 1.8 8.9 9.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal D-ser_dehydrat PF14031.1 KFX90756.1 - 3.4e-07 30.3 0.0 6.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain PCRF PF03462.13 KFX90760.1 - 1.4e-25 89.2 0.0 2.9e-25 88.2 0.0 1.5 2 0 0 2 2 2 1 PCRF domain EDR1 PF14381.1 KFX90760.1 - 0.089 12.3 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 RRM_1 PF00076.17 KFX90763.1 - 2.7e-10 39.7 2.4 6.5e-10 38.5 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX90763.1 - 1.3e-08 34.7 0.2 3e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX90763.1 - 4.4e-07 29.6 0.1 0.00051 19.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.9 KFX90763.1 - 0.075 13.0 0.1 0.075 13.0 0.1 3.9 2 1 0 2 2 2 0 RNA polymerase III RPC4 TFIIF_alpha PF05793.7 KFX90763.1 - 0.16 10.2 30.1 0.28 9.5 20.9 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ycf1 PF05758.7 KFX90763.1 - 2.3 5.8 5.3 3.2 5.3 3.7 1.2 1 0 0 1 1 1 0 Ycf1 Sds3 PF08598.6 KFX90764.1 - 8.6e-23 80.9 7.0 8.6e-23 80.9 4.9 3.3 2 2 0 2 2 2 1 Sds3-like Coiled-coil_56 PF09813.4 KFX90765.1 - 5.6e-05 23.0 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 KFX90766.1 - 3.3e-74 249.2 0.0 6.8e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) XPC-binding PF09280.6 KFX90766.1 - 0.046 13.1 0.0 0.8 9.2 0.0 2.7 2 0 0 2 2 2 0 XPC-binding domain Fib_alpha PF08702.5 KFX90767.1 - 8.2 6.5 11.3 4.2 7.4 1.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_1 PF00036.27 KFX90771.1 - 0.00025 20.1 0.6 0.00064 18.8 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX90771.1 - 0.00069 19.2 0.4 0.0023 17.6 0.0 2.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KFX90771.1 - 0.00095 18.4 0.1 0.0027 16.9 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFX90771.1 - 0.003 17.6 0.1 0.0092 16.0 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EII-Sor PF03609.9 KFX90771.1 - 0.062 12.5 0.1 0.062 12.5 0.1 1.5 2 0 0 2 2 2 0 PTS system sorbose-specific iic component DAO PF01266.19 KFX90772.1 - 2.1e-38 132.1 0.0 2.4e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX90772.1 - 6.5e-05 22.8 0.0 0.0039 17.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX90772.1 - 0.00056 18.9 0.0 0.031 13.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 KFX90772.1 - 0.0039 15.7 0.0 0.013 13.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KFX90772.1 - 0.0054 15.6 0.1 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 KFX90772.1 - 0.0066 16.2 0.2 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX90772.1 - 0.03 14.3 0.0 7.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KFX90772.1 - 0.039 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox PF00070.22 KFX90772.1 - 0.11 12.9 0.1 5.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Adaptin_N PF01602.15 KFX90777.1 - 8.2e-107 357.6 6.0 1e-106 357.3 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KFX90777.1 - 3.7e-45 152.5 0.0 8.2e-45 151.3 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KFX90777.1 - 2.2e-21 76.3 0.0 4.4e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain CPSF_A PF03178.10 KFX90778.1 - 3.5e-68 230.0 0.0 1.4e-67 228.1 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KFX90778.1 - 2.5e-65 220.5 0.0 3.5e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4452 PF14618.1 KFX90786.1 - 1.3e-68 229.9 15.3 1.6e-68 229.6 10.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) DUF4573 PF15140.1 KFX90786.1 - 0.23 11.0 7.3 0.38 10.3 3.9 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4573) SNARE PF05739.14 KFX90789.1 - 2.3e-14 52.7 3.2 3.3e-14 52.3 2.2 1.2 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.13 KFX90789.1 - 0.013 13.6 0.3 0.013 13.5 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Phage_GP20 PF06810.6 KFX90789.1 - 0.04 13.3 0.6 0.062 12.7 0.2 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 Peptidase_M17_N PF02789.12 KFX90789.1 - 0.042 13.5 0.1 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF912 PF06024.7 KFX90789.1 - 2.2 8.3 4.3 1.2 9.1 1.3 1.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OB_NTP_bind PF07717.11 KFX90792.1 - 1e-22 80.0 0.0 2.2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX90792.1 - 1.7e-19 69.7 0.1 4e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX90792.1 - 2.2e-11 43.4 0.0 4.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFX90792.1 - 1.4e-05 25.2 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFX90792.1 - 0.0011 18.4 0.1 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 KFX90792.1 - 0.0021 17.9 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KFX90792.1 - 0.028 14.7 0.1 0.089 13.0 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KFX90792.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 KFX90792.1 - 0.057 12.3 0.1 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 KFX90792.1 - 0.06 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX90792.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NmrA PF05368.8 KFX90793.1 - 5.3e-12 45.4 0.0 8.4e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX90793.1 - 2e-05 24.7 0.0 4.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX90793.1 - 0.013 15.8 0.1 0.079 13.2 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ima1_N PF09779.4 KFX90794.1 - 4.3e-40 137.2 4.9 8.4e-40 136.2 3.4 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF1430 PF07242.6 KFX90794.1 - 0.034 14.1 0.1 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) DUF2296 PF10058.4 KFX90794.1 - 0.33 10.7 2.8 10 5.9 0.6 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Rep_fac-A_C PF08646.5 KFX90794.1 - 3.7 7.2 5.2 14 5.3 1.3 2.4 2 0 0 2 2 2 0 Replication factor-A C terminal domain Adeno_E3_CR2 PF02439.10 KFX90797.1 - 2.7e-05 23.6 3.8 4.1e-05 23.0 2.6 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.5 KFX90797.1 - 0.00026 20.2 2.4 0.00066 18.9 1.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 KFX90797.1 - 0.0075 16.0 0.3 0.022 14.5 0.2 1.8 1 0 0 1 1 1 1 Glycophorin A Mid2 PF04478.7 KFX90797.1 - 0.024 14.0 2.8 0.052 12.9 1.8 1.7 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.1 KFX90797.1 - 0.051 13.9 0.1 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 KFX90797.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Band_7 PF01145.20 KFX90799.1 - 1.4e-24 86.9 1.0 2.1e-24 86.3 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Dak1_2 PF13684.1 KFX90799.1 - 0.028 13.3 1.0 0.038 12.9 0.7 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Spindle_Spc25 PF08234.7 KFX90801.1 - 2.9e-21 75.2 0.0 1.6e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 ApoO PF09769.4 KFX90801.1 - 0.11 12.2 0.5 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein O ERM PF00769.14 KFX90801.1 - 0.13 11.7 16.3 0.23 10.9 11.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 KFX90801.1 - 0.15 10.5 3.8 0.18 10.2 2.6 1.1 1 0 0 1 1 1 0 AAA domain L_lactis_ph-MCP PF06673.6 KFX90801.1 - 0.2 10.3 3.1 0.41 9.3 2.2 1.5 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Macoilin PF09726.4 KFX90801.1 - 0.68 8.1 8.4 0.85 7.8 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 KFX90801.1 - 0.82 8.5 4.4 1.1 8.1 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PRTP PF01366.13 KFX90801.1 - 1 7.3 4.4 1.2 6.9 3.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein APG6 PF04111.7 KFX90801.1 - 2.8 6.9 7.1 4.1 6.3 4.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Rrn6 PF10214.4 KFX90807.1 - 9.7e-74 248.8 0.0 2.4e-73 247.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Pkinase PF00069.20 KFX90813.1 - 3.1e-51 174.0 0.0 4.2e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90813.1 - 5.8e-27 94.3 0.0 6.5e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX90813.1 - 0.0034 17.1 0.1 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFX90813.1 - 0.0088 14.9 0.1 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KFX90813.1 - 0.09 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 KFX90813.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 KFX90813.1 - 0.11 11.5 0.0 0.34 9.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_2 PF13532.1 KFX90814.1 - 3.7e-34 118.2 0.0 5.6e-33 114.4 0.0 2.0 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily Amidase PF01425.16 KFX90815.1 - 8.9e-96 321.4 0.0 1.1e-95 321.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Phage_Mu_Gam PF07352.7 KFX90815.1 - 0.18 11.2 0.5 0.52 9.8 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein SNF2_N PF00176.18 KFX90816.1 - 1.2e-75 254.0 0.0 1.8e-75 253.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX90816.1 - 2.2e-10 40.2 0.0 5.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX90816.1 - 1.6e-05 24.8 0.0 9e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFX90816.1 - 0.011 14.5 0.1 0.63 8.7 0.0 3.2 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.10 KFX90816.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 NAD_binding_10 PF13460.1 KFX90817.1 - 6.8e-11 42.5 0.3 9.1e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX90817.1 - 9.9e-07 28.2 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.5 KFX90817.1 - 4e-05 22.2 0.0 0.00012 20.6 0.0 1.7 2 0 0 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 KFX90817.1 - 0.0017 17.2 0.0 0.69 8.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KFX90817.1 - 0.0022 16.7 0.0 0.0072 15.0 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX90817.1 - 0.0051 16.2 0.0 0.0099 15.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX90817.1 - 0.018 15.3 0.0 0.038 14.2 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFX90817.1 - 0.024 13.5 0.0 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1471 PF07338.8 KFX90817.1 - 0.095 12.3 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) FAD_binding_1 PF00667.15 KFX90818.1 - 5.9e-61 205.6 0.0 1.6e-60 204.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KFX90818.1 - 1.5e-11 44.7 0.0 5.2e-11 43.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KFX90818.1 - 6.9e-10 39.1 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KFX90818.1 - 0.0034 17.3 0.4 0.013 15.4 0.1 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 KFX90818.1 - 0.079 13.0 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain ArfGap PF01412.13 KFX90824.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Sugar_tr PF00083.19 KFX90834.1 - 1.3e-75 254.7 22.5 1.6e-75 254.4 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90834.1 - 2e-13 49.8 26.4 2e-13 49.8 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_6 PF03737.10 KFX90835.1 - 2.9e-28 98.6 0.5 3.6e-28 98.3 0.3 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase 2-Hacid_dh_C PF02826.14 KFX90836.1 - 3.3e-55 185.9 0.0 4.5e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX90836.1 - 3.2e-26 91.3 0.0 4e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX90836.1 - 1.6e-05 24.7 0.1 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX90836.1 - 0.031 14.7 0.2 0.09 13.2 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KFX90836.1 - 0.085 13.3 0.0 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_2 PF02615.9 KFX90837.1 - 5.6e-93 311.3 0.0 6.6e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Gly_rich_SFCGS PF14272.1 KFX90837.1 - 0.085 12.7 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Glycine-rich SFCGS MFS_1 PF07690.11 KFX90838.1 - 1.2e-26 93.2 24.5 1.2e-26 93.2 17.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KFX90838.1 - 2.7 8.1 9.7 13 5.9 0.0 4.1 4 2 2 6 6 6 0 NfeD-like C-terminal, partner-binding Fungal_trans PF04082.13 KFX90839.1 - 4.6e-24 84.6 0.4 8.1e-24 83.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 KFX90839.1 - 1.1e-20 74.3 0.1 1.8e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Zn_clus PF00172.13 KFX90839.1 - 3.2e-08 33.3 9.6 5.9e-08 32.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBA_3 PF09288.5 KFX90839.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain adh_short PF00106.20 KFX90842.1 - 2.1e-14 53.7 0.0 3.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX90842.1 - 7e-07 29.0 0.0 9.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NACHT PF05729.7 KFX90842.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 NACHT domain NAD_binding_4 PF07993.7 KFX90842.1 - 0.15 10.9 0.0 0.32 9.8 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein PAN_1 PF00024.21 KFX90843.1 - 0.00025 20.7 2.6 0.13 11.9 0.1 3.5 3 0 0 3 3 3 2 PAN domain zf-C2H2_4 PF13894.1 KFX90845.1 - 1.5e-06 28.1 7.1 0.0062 16.7 0.2 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger mTERF PF02536.9 KFX90845.1 - 0.0085 14.7 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 mTERF DUF4559 PF15112.1 KFX90845.1 - 0.059 12.5 0.3 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) AOX PF01786.12 KFX90846.1 - 6.5e-86 287.0 0.0 7.9e-86 286.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short PF00106.20 KFX90851.1 - 2.3e-23 82.9 0.4 3.1e-23 82.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX90851.1 - 1.7e-18 67.2 0.2 2.3e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX90851.1 - 3.4e-12 46.4 0.3 4.6e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX90851.1 - 1.4e-09 38.2 0.1 2.1e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFX90851.1 - 0.00026 20.6 0.0 0.00098 18.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KFX90851.1 - 0.032 13.4 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.16 KFX90851.1 - 0.063 12.7 0.1 0.1 12.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 KFX90852.1 - 5.4e-90 302.1 18.7 6.7e-90 301.8 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90852.1 - 7.3e-33 113.7 45.0 1.8e-26 92.7 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX90852.1 - 0.0002 21.0 0.5 0.083 12.6 0.1 2.9 2 0 0 2 2 2 2 MFS_1 like family UPF0075 PF03702.9 KFX90853.1 - 3.2e-87 292.7 0.0 3.8e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Fibrillarin_2 PF10113.4 KFX90853.1 - 0.014 13.7 0.0 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Peptidase_M22 PF00814.20 KFX90853.1 - 0.015 14.8 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Glycoprotease family IRK_N PF08466.5 KFX90853.1 - 0.2 11.5 0.8 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal UPF0075 PF03702.9 KFX90854.1 - 3.3e-63 213.7 0.0 1.8e-62 211.3 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0075) Sugar_tr PF00083.19 KFX90855.1 - 3e-91 306.2 21.0 3.5e-91 306.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90855.1 - 6.9e-25 87.5 45.2 1.2e-22 80.0 17.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFX90856.1 - 2.3e-12 46.2 3.9 2.3e-12 46.2 2.7 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90856.1 - 5.6 6.9 6.3 0.3 11.0 0.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX90857.1 - 1.1e-17 63.7 0.1 1.8e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90857.1 - 0.0004 20.2 10.8 0.00073 19.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BT1 PF03092.11 KFX90857.1 - 0.053 12.2 0.0 0.23 10.1 0.0 1.8 2 0 0 2 2 2 0 BT1 family TraX PF05857.6 KFX90857.1 - 0.11 12.1 0.5 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 TraX protein Fungal_trans PF04082.13 KFX90858.1 - 3.6e-33 114.5 0.1 5.2e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90858.1 - 3e-08 33.4 11.8 4.9e-08 32.7 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KFX90858.1 - 5.7e-05 22.9 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.19 KFX90859.1 - 2.2e-116 389.1 20.2 3.7e-116 388.3 14.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90859.1 - 1.1e-24 86.8 61.3 3.8e-17 62.0 22.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_17 PF13207.1 KFX90860.1 - 3.4e-06 27.8 0.0 2e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFX90860.1 - 4.7e-06 26.2 0.0 5.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KFX90860.1 - 0.0002 21.3 0.0 0.00026 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KFX90860.1 - 0.00028 21.1 0.1 0.002 18.4 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 KFX90860.1 - 0.00072 19.5 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.17 KFX90860.1 - 0.0012 17.7 0.0 0.076 11.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 KFX90860.1 - 0.0014 17.8 0.1 0.0029 16.7 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KFX90860.1 - 0.0015 18.4 0.2 0.067 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFX90860.1 - 0.0057 16.2 0.1 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX90860.1 - 0.016 14.9 1.2 0.072 12.8 0.1 2.5 2 1 1 3 3 3 0 Part of AAA domain AAA_26 PF13500.1 KFX90860.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 KFX90860.1 - 0.025 13.9 0.5 4.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase ArgK PF03308.11 KFX90860.1 - 0.028 13.1 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 KFX90860.1 - 0.034 13.0 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 KFX90860.1 - 0.038 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 KFX90860.1 - 0.044 12.9 0.0 0.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 KFX90860.1 - 0.046 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFX90860.1 - 0.056 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 KFX90860.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KFX90860.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KFX90860.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 KFX90860.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.22 KFX90860.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Dicty_CAR PF05462.6 KFX90861.1 - 1.1e-12 47.4 14.3 2.2e-12 46.5 5.6 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KFX90861.1 - 6.2e-07 28.8 4.2 8.6e-07 28.3 2.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFX90861.1 - 3.7e-05 23.4 11.0 3.7e-05 23.4 7.6 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Adeno_E3_CR2 PF02439.10 KFX90861.1 - 0.071 12.6 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ABC2_membrane PF01061.19 KFX90875.1 - 2e-46 157.8 37.1 2.5e-26 92.1 5.8 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFX90875.1 - 3.2e-34 118.1 0.0 5.1e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFX90875.1 - 1.8e-16 60.9 0.1 2.1e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 KFX90875.1 - 5.1e-06 26.3 0.7 0.21 11.5 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KFX90875.1 - 4.8e-05 22.6 0.1 0.048 12.8 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX90875.1 - 5.6e-05 23.5 0.0 9.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KFX90875.1 - 0.0013 17.8 0.0 3.4 6.6 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.1 KFX90875.1 - 0.0015 18.5 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFX90875.1 - 0.0031 16.7 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX90875.1 - 0.0043 16.5 0.1 0.0096 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX90875.1 - 0.0046 17.0 0.0 0.022 14.9 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KFX90875.1 - 0.0056 16.1 0.1 0.11 11.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain PDR_assoc PF08370.6 KFX90875.1 - 0.033 13.6 0.1 0.15 11.5 0.0 2.2 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_28 PF13521.1 KFX90875.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFX90875.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KFX90875.1 - 0.078 12.4 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KFX90875.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 KFX90875.1 - 0.12 13.2 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX90875.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KFX90875.1 - 0.22 10.9 0.1 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TMEM154 PF15102.1 KFX90876.1 - 0.0031 17.2 0.2 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.7 KFX90876.1 - 0.004 17.0 3.4 0.0059 16.4 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF1517 PF07466.6 KFX90876.1 - 0.013 14.5 1.0 0.018 14.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1191 PF06697.7 KFX90876.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 KFX90876.1 - 0.038 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Plasmodium_Vir PF05795.6 KFX90876.1 - 0.056 12.6 0.3 0.071 12.3 0.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MGC-24 PF05283.6 KFX90876.1 - 0.064 13.0 9.2 0.096 12.4 6.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) RIC3 PF15361.1 KFX90876.1 - 0.1 12.8 0.1 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Adeno_E3_CR2 PF02439.10 KFX90876.1 - 0.22 11.1 2.0 0.38 10.3 1.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 KFX90876.1 - 0.37 10.1 4.4 0.36 10.1 2.0 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain CCDC50_N PF15295.1 KFX90877.1 - 0.0021 17.9 0.2 0.57 10.1 0.0 2.2 1 1 1 2 2 2 2 Coiled-coil domain-containing protein 50 N-terminus Hamartin PF04388.7 KFX90877.1 - 0.48 9.0 17.2 0.63 8.6 11.9 1.1 1 0 0 1 1 1 0 Hamartin protein DUF1517 PF07466.6 KFX90877.1 - 6.4 5.6 7.3 0.14 11.1 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) CAP59_mtransfer PF11735.3 KFX90878.1 - 2.7e-65 219.9 0.0 3.7e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 APH PF01636.18 KFX90879.1 - 0.00016 21.5 0.0 0.00054 19.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family ADH_zinc_N PF00107.21 KFX90880.1 - 2.4e-06 27.1 0.1 2.4e-06 27.1 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX90880.1 - 4.2e-06 26.4 0.0 1.4e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SSF PF00474.12 KFX90881.1 - 1.5e-21 76.5 30.8 2.5e-21 75.8 21.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF997 PF06196.7 KFX90881.1 - 0.19 11.2 11.6 0.51 9.8 0.5 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Bac_luciferase PF00296.15 KFX90882.1 - 1.1e-60 205.3 0.4 1.4e-60 205.0 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_43 PF04616.9 KFX90883.1 - 3.5e-13 49.2 0.1 8.6e-13 48.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans_2 PF11951.3 KFX90883.1 - 0.00085 18.0 0.0 0.0094 14.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_N_3 PF13417.1 KFX90884.1 - 2.6e-06 27.5 0.0 2.2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain NAD_binding_1 PF00175.16 KFX90884.1 - 5.8e-06 26.8 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFX90884.1 - 1.4e-05 25.0 0.0 0.004 17.2 0.0 2.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFX90884.1 - 2.3e-05 24.3 0.0 0.00014 21.8 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain GST_N_2 PF13409.1 KFX90884.1 - 0.00054 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX90884.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyridox_oxidase PF01243.15 KFX90884.1 - 0.012 15.6 0.0 9.2 6.3 0.0 2.9 2 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase GST_C_3 PF14497.1 KFX90885.1 - 1.6e-06 28.5 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFX90885.1 - 0.00015 21.8 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX90885.1 - 0.00026 20.8 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX90885.1 - 0.0011 18.7 0.0 0.0034 17.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX90885.1 - 0.022 14.9 0.0 0.065 13.4 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Fungal_trans PF04082.13 KFX90886.1 - 6.1e-08 31.8 0.3 1.3e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90886.1 - 2.9e-07 30.2 13.4 9.2e-07 28.6 9.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KFX90887.1 - 1.4e-47 162.2 0.0 2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX90887.1 - 6.1e-34 117.3 0.1 1.1e-33 116.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX90887.1 - 7.5e-06 25.0 0.0 0.032 13.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX90887.1 - 8.1e-05 21.6 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX90887.1 - 0.00057 19.8 0.0 0.0038 17.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX90887.1 - 0.00094 18.1 0.0 0.062 12.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 KFX90887.1 - 0.0039 16.0 0.0 0.38 9.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFX90887.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EHN PF06441.7 KFX90887.1 - 0.048 13.5 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus HI0933_like PF03486.9 KFX90887.1 - 0.12 10.8 0.0 1.4 7.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KFX90887.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding NMO PF03060.10 KFX90889.1 - 2.8e-16 59.5 0.3 3.2e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 KFX90889.1 - 0.00092 18.1 4.3 0.0012 17.7 3.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFX90889.1 - 0.012 14.5 0.6 0.018 13.9 0.4 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase IMPDH PF00478.20 KFX90889.1 - 0.12 11.2 3.0 0.16 10.7 2.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NmrA PF05368.8 KFX90890.1 - 2.1e-33 115.5 0.0 2.6e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX90890.1 - 3.3e-05 23.9 0.2 4.6e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFX90890.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 KFX90890.1 - 0.015 14.7 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX90890.1 - 0.051 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFX90890.1 - 0.095 12.3 0.3 0.37 10.4 0.1 1.9 1 1 1 2 2 2 0 KR domain FAD_binding_4 PF01565.18 KFX90891.1 - 6.2e-15 54.8 0.0 1.3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KFX90892.1 - 4e-34 117.8 32.7 4e-34 117.8 22.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Bestrophin PF01062.16 KFX90892.1 - 0.32 9.9 2.9 1 8.2 2.0 1.8 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel BRCT PF00533.21 KFX90893.1 - 0.00072 19.6 0.0 0.0037 17.3 0.0 2.2 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain adh_short_C2 PF13561.1 KFX90894.1 - 2.8e-21 76.4 1.1 4.6e-21 75.7 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX90894.1 - 1.2e-18 67.6 3.2 1.2e-18 67.6 2.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX90894.1 - 1e-06 28.5 3.1 1.5e-05 24.7 2.1 2.3 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KFX90894.1 - 0.0046 15.8 2.9 0.21 10.4 0.6 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 KFX90894.1 - 0.0077 15.4 0.1 0.018 14.2 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX90894.1 - 0.013 15.2 0.8 0.033 13.9 0.3 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 KFX90894.1 - 0.014 14.8 0.2 0.19 11.1 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3698 PF12479.3 KFX90894.1 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) ApbA PF02558.11 KFX90894.1 - 0.043 13.2 0.1 0.086 12.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX90894.1 - 0.061 12.9 3.2 0.08 12.5 0.5 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3150 PF11348.3 KFX90894.1 - 0.092 11.8 1.1 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) Pkinase PF00069.20 KFX90895.1 - 4.7e-15 55.4 0.0 9.5e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain VWA_2 PF13519.1 KFX90895.1 - 0.00084 19.4 0.1 0.0026 17.9 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Pkinase_Tyr PF07714.12 KFX90895.1 - 0.0054 15.8 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CorA PF01544.13 KFX90896.1 - 0.00025 20.1 1.3 0.00064 18.8 0.9 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein T5orf172 PF10544.4 KFX90899.1 - 1e-14 54.6 2.0 3.8e-14 52.8 0.9 2.1 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 KFX90899.1 - 5.5e-08 33.1 8.0 2.6e-05 24.5 4.7 3.2 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 DUF3359 PF11839.3 KFX90899.1 - 3.1 8.2 5.9 8.8 6.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3359) DUF2527 PF10736.4 KFX90903.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) DUF1227 PF06777.6 KFX90904.1 - 8.4e-63 210.4 0.5 2.7e-62 208.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KFX90904.1 - 1.3e-52 177.7 0.4 2.8e-52 176.6 0.3 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KFX90904.1 - 1.9e-43 148.3 0.0 5.6e-43 146.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 KFX90904.1 - 0.00025 20.9 0.7 0.033 14.0 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX90904.1 - 0.00059 19.3 0.0 0.1 12.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KFX90904.1 - 0.0015 17.3 0.0 0.016 14.0 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KFX90904.1 - 0.022 14.8 0.5 2.9 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 KFX90904.1 - 0.028 13.9 0.1 0.099 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KFX90904.1 - 0.052 12.7 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PRP3 PF08572.5 KFX90905.1 - 4.6e-70 235.4 5.2 6.6e-70 234.9 3.6 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KFX90905.1 - 3.1e-39 133.5 0.9 3.1e-39 133.5 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) EPSP_synthase PF00275.15 KFX90906.1 - 1.9e-127 425.1 0.0 2.8e-127 424.6 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KFX90906.1 - 1.1e-99 332.6 0.0 2.2e-99 331.6 0.0 1.6 1 0 0 1 1 1 1 3-dehydroquinate synthase RNA_pol_Rpb1_5 PF04998.12 KFX90906.1 - 1.4e-88 296.7 0.1 2.7e-88 295.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFX90906.1 - 2.8e-64 216.0 0.1 5.5e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 DHquinase_I PF01487.10 KFX90906.1 - 5.8e-62 209.2 0.0 1.8e-61 207.6 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 KFX90906.1 - 4.7e-37 127.2 0.0 3e-35 121.4 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase RNA_pol_Rpb1_3 PF04983.13 KFX90906.1 - 2.6e-35 121.5 0.0 1.9e-34 118.6 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KFX90906.1 - 2e-32 112.8 0.0 2.2e-23 83.0 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 Shikimate_dh_N PF08501.6 KFX90906.1 - 4.1e-23 81.2 0.0 1.2e-22 79.7 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain RNA_pol_Rpb1_4 PF05000.12 KFX90906.1 - 1.8e-17 63.0 0.1 7.5e-17 61.0 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Shikimate_DH PF01488.15 KFX90906.1 - 1.8e-11 44.2 0.0 5.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KFX90906.1 - 4e-09 36.1 0.0 9.5e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KFX90906.1 - 0.00011 22.9 0.0 0.00049 20.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 KFX90907.1 - 3.4e-09 36.5 12.7 0.003 17.8 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX90907.1 - 6.1e-07 29.3 14.5 0.0023 18.1 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFX90907.1 - 1.2 9.2 5.9 3.5 7.8 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Histone PF00125.19 KFX90909.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFX90909.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KFX90909.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX90909.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFX90909.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFX90909.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KFX90910.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFX90910.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX90910.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFX90910.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF4131 PF13567.1 KFX90911.1 - 4.3 6.7 8.8 6 6.2 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Zn_clus PF00172.13 KFX90912.1 - 2.5e-09 36.8 8.0 5.1e-09 35.8 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX90912.1 - 2.9e-06 26.1 0.0 5.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tenui_NCP PF04876.7 KFX90912.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Ctr PF04145.10 KFX90919.1 - 1.4e-16 60.8 0.0 3.1e-16 59.7 0.0 1.5 1 1 0 1 1 1 1 Ctr copper transporter family Sod_Fe_C PF02777.13 KFX90920.1 - 1.1e-33 115.2 0.3 2e-33 114.3 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFX90920.1 - 5.6e-32 109.8 3.5 1.1e-31 108.8 2.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ferric_reduct PF01794.14 KFX90921.1 - 1.6e-16 60.5 17.4 1.6e-16 60.5 12.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFX90921.1 - 7.6e-16 57.8 0.0 1.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX90921.1 - 1.4e-11 44.5 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KFX90921.1 - 1.4 9.1 18.4 0.45 10.6 1.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ctr PF04145.10 KFX90922.1 - 3.6e-26 91.9 7.3 5.4e-26 91.3 5.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF2583 PF10762.4 KFX90922.1 - 1.7 8.8 6.6 0.65 10.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) COesterase PF00135.23 KFX90923.1 - 2.6e-91 306.9 0.0 3.2e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX90923.1 - 3.4e-05 23.5 0.1 0.00046 19.8 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX90924.1 - 2.5e-64 217.9 0.0 1.5e-29 103.1 0.0 3.0 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX90924.1 - 8.1e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KFX90924.1 - 0.0038 16.4 0.0 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase ABM PF03992.11 KFX90926.1 - 7.5e-05 22.6 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_5 PF06172.6 KFX90927.1 - 2.4e-21 76.1 0.0 3.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) COesterase PF00135.23 KFX90928.1 - 6.2e-85 285.9 0.4 2e-79 267.7 0.4 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX90928.1 - 8.5e-10 38.5 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX90928.1 - 0.0016 18.1 0.1 0.0039 16.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Oxidored_FMN PF00724.15 KFX90929.1 - 4.6e-40 137.6 0.0 1e-39 136.5 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Vps35 PF03635.12 KFX90930.1 - 3.4e-181 604.1 1.9 4.2e-155 517.9 0.7 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 BUD22 PF09073.5 KFX90930.1 - 0.00049 19.3 10.1 0.00081 18.5 7.0 1.2 1 0 0 1 1 1 1 BUD22 Bromodomain PF00439.20 KFX90931.1 - 8.9e-23 80.0 0.2 2.3e-22 78.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 KFX90931.1 - 1.6e-08 34.4 0.0 3.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX90931.1 - 4.2e-08 33.2 0.1 9e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasom_Rpn13 PF04683.8 KFX90933.1 - 2.1e-28 98.2 0.0 3.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SNF5 PF04855.7 KFX90934.1 - 1.2e-85 286.8 0.0 1.9e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Ribosomal_L6e PF01159.14 KFX90934.1 - 6.6e-36 122.8 0.3 6.6e-36 122.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e GATA PF00320.22 KFX90934.1 - 8e-05 21.9 3.2 0.0002 20.6 2.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Ribosomal_L7Ae PF01248.21 KFX90935.1 - 5.9e-23 80.1 0.0 6.7e-23 80.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family bZIP_1 PF00170.16 KFX90940.1 - 0.035 14.0 2.0 0.067 13.1 1.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor AFG1_ATPase PF03969.11 KFX90944.1 - 3.7e-97 325.3 0.0 1.3e-91 307.1 0.0 2.4 2 0 0 2 2 2 2 AFG1-like ATPase Hist_deacetyl PF00850.14 KFX90944.1 - 5.6e-61 206.5 0.1 1.1e-60 205.5 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain AAA_16 PF13191.1 KFX90944.1 - 0.00059 19.8 0.1 0.18 11.8 0.0 2.8 1 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFX90944.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFX90944.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 KFX90944.1 - 0.11 12.1 0.0 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Pkinase PF00069.20 KFX90947.1 - 3.1e-19 69.1 0.0 5.3e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90947.1 - 4.8e-15 55.3 0.0 7.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.19 KFX90947.1 - 2.6e-08 33.7 0.0 5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX90947.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX90947.1 - 4.5e-05 23.5 0.0 0.00014 21.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kdo PF06293.9 KFX90947.1 - 0.026 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAN_4 PF14295.1 KFX90948.1 - 0.0019 17.8 0.4 0.0064 16.1 0.2 1.9 1 1 0 1 1 1 1 PAN domain SSP160 PF06933.6 KFX90948.1 - 0.0079 14.2 3.2 0.011 13.7 2.2 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1628 PF07790.6 KFX90948.1 - 0.037 14.7 0.0 0.095 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Alpha_GJ PF03229.8 KFX90948.1 - 0.058 13.7 6.7 0.12 12.7 4.6 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J SpoIIIAH PF12685.2 KFX90948.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Pol_alpha_B_N PF08418.5 KFX90948.1 - 1.5 8.3 4.7 2 7.8 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TFCD_C PF12612.3 KFX90949.1 - 4.7e-27 94.6 0.0 2e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KFX90949.1 - 0.00019 21.1 5.4 0.33 11.1 0.0 6.6 6 0 0 6 6 6 1 HEAT repeat DUF1119 PF06550.6 KFX90949.1 - 0.071 12.2 0.6 0.12 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1119) HEAT_EZ PF13513.1 KFX90949.1 - 0.1 13.1 0.1 0.1 13.1 0.1 6.4 8 1 1 9 9 9 0 HEAT-like repeat SWIM PF04434.12 KFX90950.1 - 0.14 11.6 0.3 0.32 10.5 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger AA_permease_2 PF13520.1 KFX90951.1 - 1.5e-40 139.0 40.4 3.3e-40 137.9 28.0 1.6 1 1 0 1 1 1 1 Amino acid permease ABC_tran PF00005.22 KFX90952.1 - 1e-46 158.6 0.1 1.2e-24 87.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFX90952.1 - 1.2e-23 84.4 1.9 1.1e-05 25.5 0.0 4.4 4 0 0 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 KFX90952.1 - 1.4e-21 76.9 47.2 1.3e-15 57.3 16.2 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KFX90952.1 - 1.9e-10 40.0 2.0 3.9e-05 23.0 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFX90952.1 - 1.5e-08 35.1 2.8 0.0021 18.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFX90952.1 - 8.1e-08 31.7 3.1 0.081 12.1 0.2 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFX90952.1 - 5.9e-05 22.3 1.1 0.085 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX90952.1 - 0.00018 21.5 1.5 0.34 10.8 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 KFX90952.1 - 0.00026 20.1 0.0 1.1 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KFX90952.1 - 0.00085 18.4 0.3 0.44 9.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.1 KFX90952.1 - 0.0028 17.7 0.1 0.61 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX90952.1 - 0.0063 16.2 0.5 3.8 7.3 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KFX90952.1 - 0.0064 15.9 0.1 1.7 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 KFX90952.1 - 0.015 14.6 0.1 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 MutS domain V AAA_30 PF13604.1 KFX90952.1 - 0.024 14.2 3.0 2.4 7.7 0.3 2.8 2 1 1 3 3 3 0 AAA domain SbcCD_C PF13558.1 KFX90952.1 - 0.047 13.6 0.5 8.4 6.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KFX90952.1 - 0.058 13.9 0.0 4 7.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein SRP54 PF00448.17 KFX90952.1 - 0.069 12.5 0.7 9.4 5.6 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KFX90952.1 - 0.072 13.0 1.7 2.7 7.9 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFX90952.1 - 0.075 12.9 0.3 9.3 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX90952.1 - 0.1 12.0 1.6 5.4 6.3 0.4 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KFX90952.1 - 0.18 11.2 1.1 0.58 9.6 0.2 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KFX90952.1 - 0.19 11.6 0.1 14 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF4162 PF13732.1 KFX90952.1 - 0.26 11.8 0.0 0.66 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) NB-ARC PF00931.17 KFX90952.1 - 0.63 8.8 0.4 11 4.7 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 KFX90952.1 - 1.3 8.1 6.1 18 4.4 0.3 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NAD_binding_10 PF13460.1 KFX90953.1 - 6.1e-30 104.5 0.0 7.1e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX90953.1 - 6.1e-06 25.6 0.0 8.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFX90953.1 - 0.00013 21.5 0.0 0.0003 20.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TraD PF06412.6 KFX90953.1 - 0.05 13.1 0.1 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TraD RRM_1 PF00076.17 KFX90960.1 - 1.1e-15 57.0 0.0 3.3e-12 45.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX90960.1 - 2e-12 46.9 0.0 2.4e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX90960.1 - 7.2e-07 28.9 0.0 2.3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 KFX90960.1 - 0.0027 17.4 0.1 0.0081 15.9 0.0 1.9 1 1 0 1 1 1 1 'Cold-shock' DNA-binding domain Cpn60_TCP1 PF00118.19 KFX90964.1 - 5.8e-136 453.9 2.4 6.6e-136 453.7 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_61 PF03443.9 KFX90966.1 - 7e-39 133.8 0.0 9.6e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.12 KFX90967.1 - 2e-109 365.6 3.4 2.6e-109 365.2 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KFX90967.1 - 1.1e-12 47.3 12.9 1.1e-12 47.3 8.9 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX90967.1 - 1.8 8.6 10.2 0.051 13.6 1.6 2.5 3 0 0 3 3 3 0 Toxin 7 Glyco_hydro_61 PF03443.9 KFX90968.1 - 2.9e-46 158.0 0.0 3.7e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 KFX90969.1 - 6.9e-67 225.4 0.4 8.8e-67 225.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3446 PF11928.3 KFX90969.1 - 2.5 8.3 7.2 0.85 9.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3446) GMC_oxred_N PF00732.14 KFX90970.1 - 4.1e-27 95.1 0.1 7.9e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX90970.1 - 3.2e-22 79.3 0.1 6.1e-22 78.4 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX90970.1 - 1.3e-08 34.1 0.1 0.0039 16.0 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX90970.1 - 2.3e-05 23.4 0.6 0.0017 17.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX90970.1 - 0.00096 19.1 0.1 0.0037 17.2 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX90970.1 - 0.00098 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX90970.1 - 0.0029 17.7 0.1 0.019 15.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX90970.1 - 0.01 14.9 0.1 0.026 13.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KFX90970.1 - 0.02 13.9 0.1 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX90970.1 - 0.028 12.9 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KFX90970.1 - 0.032 14.6 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX90970.1 - 0.71 8.6 3.5 0.88 8.3 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Beta-lactamase PF00144.19 KFX90972.1 - 2.8e-41 141.6 0.0 3.7e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX90972.1 - 0.11 11.7 0.2 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SMI1_KNR4 PF09346.5 KFX90973.1 - 0.033 14.1 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Prismane PF03063.15 KFX90973.1 - 0.046 12.1 0.0 0.082 11.2 0.0 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF1762 PF08574.5 KFX90974.1 - 3.4e-05 24.1 13.8 3.4e-05 24.1 9.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1762) GST_N_3 PF13417.1 KFX90979.1 - 3.3e-10 40.0 0.1 7.8e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX90979.1 - 2.2e-08 34.0 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX90979.1 - 8.2e-05 22.4 0.0 0.00021 21.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX90979.1 - 0.0033 17.8 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 KFX90979.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain F-box PF00646.28 KFX90989.1 - 5e-07 29.2 0.1 9.4e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX90989.1 - 1.5e-05 24.5 0.0 4.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-C2H2_4 PF13894.1 KFX90991.1 - 1.8e-07 30.9 13.1 0.00079 19.5 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX90991.1 - 1.1e-05 25.4 13.6 0.065 13.5 1.9 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX90991.1 - 0.00011 22.3 11.4 0.17 12.2 0.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.7 KFX90991.1 - 0.023 14.7 6.5 0.087 12.9 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF605 PF04652.11 KFX90991.1 - 0.15 11.4 2.5 0.19 11.0 1.7 1.1 1 0 0 1 1 1 0 Vta1 like FPN1 PF06963.7 KFX90992.1 - 6.6e-97 324.6 10.3 8.5e-97 324.2 7.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Aha1_N PF09229.6 KFX90993.1 - 3.8e-36 123.9 0.1 5.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KFX90993.1 - 7.4e-19 68.0 1.3 1.3e-18 67.3 0.2 1.8 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 KFX90993.1 - 0.0073 16.4 2.1 0.0073 16.4 1.5 1.9 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.17 KFX90995.1 - 5.3e-61 206.5 0.0 7.2e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KFX90996.1 - 5.6e-73 246.0 35.1 6.8e-73 245.7 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90996.1 - 7.2e-21 74.2 37.5 7.2e-21 74.2 26.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFX90996.1 - 0.0035 15.4 5.7 0.011 13.8 1.5 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family CbtB PF09489.5 KFX90996.1 - 1.8 8.5 8.5 6.7 6.7 0.1 3.9 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) TPR_12 PF13424.1 KFX90997.1 - 3.3e-89 292.9 14.4 3.4e-19 68.5 0.0 4.9 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 KFX90997.1 - 7.4e-65 213.2 3.3 1.2e-10 40.9 0.0 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFX90997.1 - 2.7e-22 78.1 0.3 3.4e-08 33.0 0.0 4.5 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KFX90997.1 - 3.7e-16 57.9 8.8 0.0088 15.6 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFX90997.1 - 2.1e-15 55.3 7.5 0.032 14.1 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFX90997.1 - 2.7e-13 50.1 0.1 0.00011 22.7 0.0 5.4 4 2 2 6 6 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90997.1 - 3.7e-13 48.2 3.6 0.0023 17.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX90997.1 - 1.5e-10 40.4 1.1 6.7 7.1 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX90997.1 - 3.4e-10 39.9 0.0 0.00058 19.9 0.0 3.7 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFX90997.1 - 4.6e-10 39.2 3.5 0.037 14.6 0.0 6.2 4 2 2 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 KFX90997.1 - 1.9e-09 36.7 0.0 0.0011 17.8 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_4 PF07721.9 KFX90997.1 - 1.2e-08 34.5 0.3 0.088 13.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90997.1 - 2.4e-08 34.1 4.1 0.064 13.6 0.2 5.0 3 1 2 5 5 4 3 Tetratricopeptide repeat AAA_22 PF13401.1 KFX90997.1 - 4.3e-05 23.6 0.0 0.00052 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 KFX90997.1 - 0.00021 20.8 0.7 8.6 6.4 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 KFX90997.1 - 0.0069 16.3 0.2 0.027 14.4 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain Atu4866 PF11512.3 KFX90997.1 - 0.022 14.5 6.3 15 5.4 0.0 4.4 2 2 2 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 DUF676 PF05057.9 KFX90997.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3856 PF12968.2 KFX90997.1 - 0.26 11.1 2.5 67 3.2 0.0 3.4 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) Rab5-bind PF09311.6 KFX90997.1 - 0.97 9.2 4.7 29 4.4 0.0 3.8 4 0 0 4 4 4 0 Rabaptin-like protein TPR_3 PF07720.7 KFX90997.1 - 2.8 7.8 6.1 4.8 7.0 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX90997.1 - 8.2 7.1 10.7 51 4.6 0.1 5.7 7 0 0 7 7 4 0 Tetratricopeptide repeat APH PF01636.18 KFX90998.1 - 5.6e-38 131.0 0.0 2.3e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF86 PF01934.12 KFX90998.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF86 AA_permease_2 PF13520.1 KFX91001.1 - 4.1e-56 190.3 29.1 5.1e-56 190.0 20.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX91001.1 - 2.3e-23 82.3 31.3 4.1e-23 81.4 21.7 1.4 1 1 0 1 1 1 1 Amino acid permease Phi-29_GP3 PF05435.6 KFX91001.1 - 0.086 12.0 1.4 0.12 11.5 1.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 YbjM PF11045.3 KFX91001.1 - 2.1 8.1 7.1 7.9 6.2 0.1 3.0 3 0 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae Glyco_transf_90 PF05686.7 KFX91002.1 - 3.5e-14 52.3 3.7 2.4e-09 36.3 1.2 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L7Ae PF01248.21 KFX91003.1 - 2.5e-28 97.4 1.1 3.3e-28 97.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KFX91003.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family OPT PF03169.10 KFX91004.1 - 2.1e-97 327.0 42.5 2.4e-97 326.8 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RseC_MucC PF04246.7 KFX91004.1 - 6 6.4 13.1 6.4 6.3 0.5 3.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Beta-lactamase PF00144.19 KFX91005.1 - 4.8e-36 124.4 0.1 9.1e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase LRR_4 PF12799.2 KFX91006.1 - 7.9e-38 127.4 56.8 1.4e-09 37.3 2.0 11.3 6 3 6 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX91006.1 - 1.3e-34 117.7 55.0 1.1e-07 31.5 3.0 9.8 6 2 5 11 11 11 9 Leucine rich repeat LRR_1 PF00560.28 KFX91006.1 - 1.6e-23 79.1 53.9 0.018 15.0 0.3 16.7 16 2 1 17 17 17 8 Leucine Rich Repeat LRR_7 PF13504.1 KFX91006.1 - 6e-20 67.8 45.6 0.09 13.0 0.0 15.7 16 0 0 16 16 16 7 Leucine rich repeat LRR_6 PF13516.1 KFX91006.1 - 3.8e-07 29.4 49.0 0.73 10.0 0.4 13.1 15 1 1 16 16 16 5 Leucine Rich repeat LRR_9 PF14580.1 KFX91006.1 - 0.017 14.7 15.6 0.036 13.6 0.1 4.6 2 2 4 6 6 6 0 Leucine-rich repeat LRR_2 PF07723.8 KFX91006.1 - 1.7 9.3 6.9 14 6.3 0.3 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat WWbp PF10349.4 KFX91007.1 - 0.0098 16.7 8.6 0.012 16.4 6.0 1.1 1 0 0 1 1 1 1 WW-domain ligand protein DUF2370 PF10176.4 KFX91007.1 - 0.13 11.6 1.4 0.13 11.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) UCR_hinge PF02320.11 KFX91008.1 - 9.7e-28 95.9 6.5 1.9e-27 94.9 4.5 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Mnd1 PF03962.10 KFX91008.1 - 0.068 12.8 4.7 0.074 12.7 3.3 1.1 1 0 0 1 1 1 0 Mnd1 family YqfQ PF14181.1 KFX91008.1 - 0.19 11.7 7.1 0.25 11.3 4.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein Ycf1 PF05758.7 KFX91008.1 - 1.1 6.8 6.0 1.1 6.8 4.2 1.0 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 KFX91008.1 - 1.3 8.1 12.0 1.5 7.9 8.3 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Myc_N PF01056.13 KFX91008.1 - 2.1 7.4 13.1 2.5 7.2 9.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 KFX91008.1 - 2.6 6.4 17.6 2.7 6.3 12.2 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KFX91008.1 - 3.1 5.7 6.9 3 5.7 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF740 PF05340.7 KFX91008.1 - 3.1 6.0 9.2 3.4 5.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RR_TM4-6 PF06459.7 KFX91008.1 - 4.8 6.9 13.0 5.1 6.9 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 KFX91008.1 - 5.9 6.2 12.6 7.5 5.9 8.7 1.1 1 0 0 1 1 1 0 DDRGK domain RNA_polI_A34 PF08208.6 KFX91008.1 - 6.1 6.4 11.3 6.7 6.3 7.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3530 PF12048.3 KFX91008.1 - 6.1 5.7 9.0 7 5.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Merozoite_SPAM PF07133.6 KFX91008.1 - 7.1 6.4 21.9 9.5 6.0 15.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HSP90 PF00183.13 KFX91008.1 - 7.2 4.8 17.6 8 4.7 12.2 1.0 1 0 0 1 1 1 0 Hsp90 protein Spore_coat_CotO PF14153.1 KFX91008.1 - 7.7 5.9 12.3 9.9 5.5 8.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Lipase_GDSL_2 PF13472.1 KFX91009.1 - 4.2e-16 59.5 1.2 5.1e-16 59.3 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX91009.1 - 5.5e-10 39.4 1.2 6.7e-10 39.1 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_35 PF01301.14 KFX91010.1 - 1.4e-76 257.8 5.6 2.6e-76 257.0 3.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KFX91010.1 - 9.7e-55 184.7 5.6 1.9e-54 183.8 3.8 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KFX91010.1 - 1.5e-48 163.6 1.4 6.1e-25 87.6 0.7 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KFX91010.1 - 7.7e-25 86.1 0.4 3.9e-24 83.8 0.4 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Pyr_redox_2 PF07992.9 KFX91011.1 - 3e-11 43.5 0.0 6.5e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX91011.1 - 7.7e-10 39.0 0.5 3.7e-07 30.4 0.4 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX91011.1 - 1.1e-05 25.6 0.0 0.053 13.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX91011.1 - 2.4e-05 23.4 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFX91011.1 - 9.6e-05 22.2 3.0 0.33 10.7 0.0 4.4 5 1 1 6 6 6 2 FAD-NAD(P)-binding DAO PF01266.19 KFX91011.1 - 0.00016 20.7 6.8 0.026 13.4 0.1 3.7 3 1 0 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFX91011.1 - 0.035 12.7 0.4 5.1 5.5 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.11 KFX91012.1 - 7e-28 97.3 52.5 1.6e-15 56.7 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX91012.1 - 0.00019 21.1 2.5 0.00019 21.1 1.7 3.0 4 0 0 4 4 4 1 MFS_1 like family Sugar_tr PF00083.19 KFX91012.1 - 0.00092 17.9 6.1 0.00092 17.9 4.2 4.1 1 1 2 3 3 3 2 Sugar (and other) transporter DUF1072 PF06380.6 KFX91012.1 - 1.2 8.8 8.4 4.8 6.9 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Cutinase PF01083.17 KFX91013.1 - 7.7e-53 178.8 3.7 9.7e-53 178.5 2.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFX91013.1 - 0.0043 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KFX91013.1 - 0.065 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) adh_short PF00106.20 KFX91016.1 - 1.4e-17 64.1 4.3 1.9e-17 63.6 3.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91016.1 - 1.5e-10 41.0 2.3 2.2e-10 40.4 1.6 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.3 KFX91017.1 - 3.3e-05 22.6 0.1 9.1e-05 21.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Trp_oprn_chp PF09534.5 KFX91018.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1970 PF09301.5 KFX91018.1 - 0.12 12.4 5.7 5.2 7.1 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1970) Abhydrolase_2 PF02230.11 KFX91019.1 - 5.7e-26 91.3 0.0 8.9e-18 64.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFX91019.1 - 0.00025 20.9 0.3 0.026 14.4 0.6 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX91019.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX91019.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Gpi1 PF05024.10 KFX91027.1 - 2.7e-65 219.5 9.2 2.7e-65 219.5 6.4 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.16 KFX91027.1 - 0.0069 15.5 0.6 0.0069 15.5 0.4 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) UPF0203 PF05254.7 KFX91028.1 - 4.4e-28 96.9 0.3 5.3e-28 96.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KFX91028.1 - 0.00094 19.1 0.2 0.0022 17.9 0.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFX91028.1 - 0.002 17.8 2.1 0.093 12.5 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KFX91028.1 - 0.21 11.5 1.6 6.2 6.8 1.2 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DNA_pol_A_exo1 PF01612.15 KFX91029.1 - 5.2e-39 133.5 0.1 7.5e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KFX91029.1 - 1.3e-25 89.5 0.0 2.9e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KFX91029.1 - 3.2e-14 52.3 0.0 9.8e-14 50.8 0.0 1.9 1 0 0 1 1 1 1 HRDC domain DUF2833 PF11090.3 KFX91029.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) RasGAP PF00616.14 KFX91030.1 - 7.2e-55 185.7 0.2 2.3e-54 184.0 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KFX91030.1 - 1.4e-27 96.1 3.0 1.4e-27 96.1 2.1 2.3 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.17 KFX91030.1 - 0.074 12.7 0.0 6.6 6.5 0.0 2.7 2 0 0 2 2 2 0 MarR family DUF972 PF06156.8 KFX91030.1 - 0.63 10.4 9.3 7.8 6.8 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SSDP PF04503.8 KFX91034.1 - 1.3 8.7 7.1 1.4 8.6 4.9 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP Cpn60_TCP1 PF00118.19 KFX91038.1 - 2.2e-160 534.4 0.3 2.5e-160 534.3 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SH3_3 PF08239.6 KFX91040.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Chlorosome_CsmC PF11098.3 KFX91043.1 - 6.1 6.5 15.4 15 5.3 10.7 1.8 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF4449 PF14613.1 KFX91049.1 - 2.3e-63 213.0 1.3 2.3e-63 213.0 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RasGEF PF00617.14 KFX91050.1 - 1.4e-62 210.7 0.0 2.4e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFX91050.1 - 2.3e-26 91.8 0.3 6.8e-26 90.4 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF4238 PF14022.1 KFX91050.1 - 8.9e-23 80.9 0.1 1.6e-22 80.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) SH3_1 PF00018.23 KFX91050.1 - 1.1e-15 56.7 0.1 2.4e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX91050.1 - 3.4e-14 52.1 0.2 7.7e-14 51.0 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX91050.1 - 1.4e-13 50.1 0.2 7.4e-13 47.7 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.21 KFX91050.1 - 4e-05 23.3 0.0 8.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 WW domain DUF726 PF05277.7 KFX91053.1 - 7.5e-127 422.9 2.3 1e-126 422.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) UPF0565 PF10561.4 KFX91053.1 - 0.21 10.4 0.0 0.58 8.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Pkinase PF00069.20 KFX91054.1 - 2.8e-16 59.4 0.0 2e-15 56.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91054.1 - 2.7e-13 49.6 0.0 3.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX91054.1 - 0.0009 18.2 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX91054.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.22 KFX91055.1 - 1.6e-48 164.4 0.1 6.4e-28 97.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFX91055.1 - 1.9e-25 89.6 47.1 5.1e-18 65.2 8.5 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFX91055.1 - 2.5e-23 83.4 0.0 2e-06 28.0 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KFX91055.1 - 1.1e-07 31.3 2.3 1.9e-05 24.0 0.0 3.6 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX91055.1 - 2.4e-06 28.0 3.4 0.0065 16.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX91055.1 - 2.8e-06 26.7 0.9 0.091 12.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFX91055.1 - 4.7e-05 22.6 0.0 0.47 9.4 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 KFX91055.1 - 0.00013 21.6 3.9 0.094 12.4 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 KFX91055.1 - 0.0002 21.0 0.2 0.06 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFX91055.1 - 0.00025 20.2 0.1 0.054 12.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 KFX91055.1 - 0.01 16.0 0.3 2.7 8.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFX91055.1 - 0.011 15.9 0.0 0.85 9.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KFX91055.1 - 0.027 14.4 0.6 2.2 8.2 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KFX91055.1 - 0.037 13.4 1.7 1.2 8.5 0.3 2.6 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 KFX91055.1 - 0.04 12.9 0.1 0.87 8.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KFX91055.1 - 0.047 13.8 0.8 6.7 6.8 0.1 3.0 2 2 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFX91055.1 - 0.074 13.0 0.5 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFX91055.1 - 0.083 12.2 0.5 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFX91055.1 - 0.092 12.1 0.6 53 3.1 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein UPF0079 PF02367.12 KFX91055.1 - 0.13 11.8 0.3 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 KFX91055.1 - 0.18 11.1 4.7 1.1 8.6 0.2 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFX91055.1 - 0.22 11.1 1.4 12 5.5 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.10 KFX91055.1 - 0.41 9.2 0.0 9.9 4.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MIP PF00230.15 KFX91056.1 - 1.6e-28 99.7 9.3 2.9e-28 98.8 6.4 1.4 1 1 0 1 1 1 1 Major intrinsic protein Glyco_hydro_30 PF02055.11 KFX91057.1 - 3.2e-30 104.7 0.5 4.4e-30 104.3 0.4 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KFX91057.1 - 0.0026 16.7 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_76 PF03663.9 KFX91058.1 - 3e-145 484.2 17.5 4e-145 483.8 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFX91058.1 - 0.016 14.2 7.4 0.82 8.6 0.3 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 CD36 PF01130.16 KFX91058.1 - 0.079 11.2 0.2 0.12 10.6 0.1 1.2 1 0 0 1 1 1 0 CD36 family zf-Di19 PF05605.7 KFX91061.1 - 0.033 14.3 0.1 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KFX91061.1 - 0.064 13.6 0.7 0.52 10.7 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX91061.1 - 0.12 12.7 0.9 1.1 9.7 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pneumo_att_G PF05539.6 KFX91061.1 - 2.5 7.4 6.5 3.1 7.0 4.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G zf-C2H2_2 PF12756.2 KFX91062.1 - 2.5e-32 111.0 8.0 1.5e-26 92.4 0.4 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFX91062.1 - 0.0052 16.9 1.5 0.0052 16.9 1.0 3.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 KFX91062.1 - 0.016 14.9 6.8 0.018 14.8 0.2 3.2 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 KFX91062.1 - 0.022 14.8 0.0 0.022 14.8 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX91062.1 - 0.4 10.6 0.1 0.4 10.6 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger HECT PF00632.20 KFX91063.1 - 9.9e-67 225.3 0.0 1.5e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MFS_1 PF07690.11 KFX91063.1 - 1.6e-35 122.5 27.6 1.6e-35 122.5 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX91063.1 - 0.00021 19.6 3.1 0.00035 18.9 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4576 PF15144.1 KFX91063.1 - 0.037 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DUF3169 PF11368.3 KFX91063.1 - 8.4 5.5 6.7 12 4.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) ABM PF03992.11 KFX91065.1 - 0.027 14.4 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Asp PF00026.18 KFX91066.1 - 6.3e-72 242.4 9.1 7.4e-72 242.2 6.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX91066.1 - 1.1e-08 35.1 0.1 9.4e-08 32.1 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX91066.1 - 7.2e-05 23.2 2.6 0.0007 20.0 0.5 2.9 2 1 0 2 2 2 1 Aspartyl protease SBP_bac_11 PF13531.1 KFX91066.1 - 0.0091 15.6 1.1 0.85 9.2 0.0 2.3 1 1 1 2 2 2 2 Bacterial extracellular solute-binding protein DUF2373 PF10180.4 KFX91071.1 - 2.7e-21 74.8 0.2 1.5e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Methyltransf_1N PF02870.10 KFX91071.1 - 0.077 13.5 0.2 1 10.0 0.1 2.7 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Proteasome PF00227.21 KFX91072.1 - 6.6e-49 165.7 0.0 9.1e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX91072.1 - 5.4e-13 47.9 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 KFX91072.1 - 0.026 14.7 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF3650 PF12368.3 KFX91072.1 - 0.38 10.3 3.6 0.17 11.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Transglut_core3 PF13471.1 KFX91073.1 - 0.099 12.4 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Glyco_hydro_18 PF00704.23 KFX91074.1 - 1e-60 206.0 6.8 5.8e-60 203.5 4.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX91074.1 - 1.6e-13 50.3 104.3 1.8e-05 24.6 9.1 4.8 4 0 0 4 4 4 4 Chitin recognition protein Cutinase PF01083.17 KFX91076.1 - 0.00028 20.6 0.0 0.0007 19.3 0.0 1.7 1 0 0 1 1 1 1 Cutinase FYVE PF01363.16 KFX91076.1 - 0.00028 20.6 15.4 0.0019 18.0 3.5 2.4 2 0 0 2 2 2 2 FYVE zinc finger Abhydrolase_6 PF12697.2 KFX91076.1 - 0.0017 18.2 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFX91076.1 - 0.0021 17.7 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX91076.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KFX91076.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 KFX91076.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF726 PF05277.7 KFX91076.1 - 0.2 10.4 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) ZZ PF00569.12 KFX91076.1 - 4.7 6.8 32.4 5.3 6.6 6.9 3.3 2 1 1 3 3 3 0 Zinc finger, ZZ type DUF3180 PF11377.3 KFX91077.1 - 0.047 13.5 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Ribosomal_L22 PF00237.14 KFX91083.1 - 4.2e-17 62.0 0.2 2.9e-15 56.1 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e RRM_1 PF00076.17 KFX91084.1 - 2e-47 158.6 0.0 2e-14 52.9 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX91084.1 - 1.5e-38 130.5 0.0 4.4e-12 45.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91084.1 - 4.1e-24 84.1 0.0 5.1e-07 29.4 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX91084.1 - 0.00012 21.8 0.0 1 9.1 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 KFX91084.1 - 0.0021 17.4 0.2 0.0053 16.1 0.1 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_3 PF08777.6 KFX91084.1 - 0.027 14.2 0.3 0.27 11.0 0.1 2.8 3 0 0 3 3 3 0 RNA binding motif TPR_14 PF13428.1 KFX91084.1 - 2.4 9.0 9.6 10 7.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_M43 PF05572.8 KFX91085.1 - 5.2e-13 48.8 0.0 9.5e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KFX91085.1 - 1.7e-05 25.3 0.1 4.6e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFX91085.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFX91085.1 - 0.0016 18.3 0.3 0.24 11.3 0.1 2.3 2 0 0 2 2 2 2 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFX91085.1 - 0.0025 17.3 0.2 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Sulfate_transp PF00916.15 KFX91086.1 - 2e-08 33.6 1.9 2e-08 33.6 1.3 2.8 2 1 1 3 3 3 1 Sulfate transporter family PepSY_TM_1 PF13172.1 KFX91086.1 - 0.23 11.2 7.1 0.58 9.9 3.3 3.1 1 1 1 2 2 2 0 PepSY-associated TM helix MRC1 PF09444.5 KFX91087.1 - 4.3e-39 134.1 19.0 4.3e-39 134.1 13.2 7.6 4 2 4 8 8 8 1 MRC1-like domain RabGAP-TBC PF00566.13 KFX91088.1 - 5.4e-47 160.0 0.0 1.2e-46 158.9 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 KFX91089.1 - 4e-36 122.4 0.2 4.9e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX91089.1 - 2.4e-27 94.7 0.1 8.1e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91089.1 - 1.9e-13 50.0 0.1 5.4e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX91089.1 - 0.018 14.8 0.1 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif UTP15_C PF09384.5 KFX91090.1 - 2.1e-47 160.5 0.0 3.6e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KFX91090.1 - 1.2e-29 101.1 5.5 8.3e-10 38.1 0.0 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat Utp12 PF04003.7 KFX91090.1 - 0.049 13.5 0.2 1.1 9.1 0.1 2.4 1 1 0 1 1 1 0 Dip2/Utp12 Family OB_NTP_bind PF07717.11 KFX91091.1 - 1.6e-25 89.1 0.0 3.9e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX91091.1 - 2e-24 85.5 0.2 2e-24 85.5 0.1 2.7 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX91091.1 - 4.1e-13 48.9 0.0 1.6e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFX91091.1 - 6.2e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFX91091.1 - 0.00019 20.9 0.0 0.00055 19.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KFX91091.1 - 0.00054 18.9 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein GYD PF08734.6 KFX91091.1 - 0.011 15.3 1.5 15 5.3 0.0 4.3 5 0 0 5 5 5 0 GYD domain AAA_14 PF13173.1 KFX91091.1 - 0.02 14.7 0.7 0.19 11.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFX91091.1 - 0.041 14.1 1.4 0.12 12.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter SRP54 PF00448.17 KFX91091.1 - 0.05 13.0 0.1 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KFX91091.1 - 0.057 13.1 0.1 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KFX91091.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.7 2 1 0 2 2 1 0 AAA domain DnaJ PF00226.26 KFX91092.1 - 9.9e-26 89.2 0.9 1.6e-25 88.6 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFX91092.1 - 1.9e-16 59.8 14.1 3.4e-16 59.0 9.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KFX91092.1 - 3.7e-13 49.1 0.0 4.5e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 KFX91092.1 - 0.027 14.1 7.5 0.76 9.4 0.6 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family adh_short PF00106.20 KFX91095.1 - 6.2e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91095.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF3425 PF11905.3 KFX91096.1 - 9.1e-33 113.0 1.5 1.7e-32 112.1 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Cwf_Cwc_15 PF04889.7 KFX91096.1 - 0.043 13.5 2.3 0.071 12.8 1.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAP PF00188.21 KFX91097.1 - 4.5e-12 46.5 2.4 5.3e-12 46.3 1.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CBM_19 PF03427.8 KFX91097.1 - 0.062 13.0 1.3 0.11 12.2 0.9 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) MFS_1 PF07690.11 KFX91100.1 - 1e-35 123.1 27.9 1e-35 123.1 19.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX91100.1 - 8.8e-06 24.5 8.7 8.8e-06 24.5 6.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFX91100.1 - 5.4e-05 21.5 3.9 0.0001 20.6 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA PF00004.24 KFX91101.1 - 2.1e-19 70.0 0.0 2.2e-17 63.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX91101.1 - 8.6e-10 38.8 0.0 8.6e-05 22.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KFX91101.1 - 1.5e-09 37.7 0.0 1.4e-06 28.0 0.0 3.0 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 KFX91101.1 - 4.6e-07 30.6 0.3 0.018 15.8 0.0 3.8 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.1 KFX91101.1 - 2.1e-06 28.0 0.0 0.073 13.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX91101.1 - 2.5e-06 27.6 1.6 0.14 12.1 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 KFX91101.1 - 6.7e-05 23.0 0.1 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KFX91101.1 - 0.00045 20.1 0.2 2.2 8.2 0.0 3.4 4 0 0 4 4 2 2 AAA domain NB-ARC PF00931.17 KFX91101.1 - 0.00084 18.2 0.1 0.18 10.6 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 KFX91101.1 - 0.0027 17.1 1.6 0.029 13.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 KFX91101.1 - 0.0031 17.1 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX91101.1 - 0.0033 16.9 0.2 0.097 12.0 0.0 3.0 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 KFX91101.1 - 0.0034 17.0 0.0 3.3 7.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Ank PF00023.25 KFX91101.1 - 0.004 16.8 0.0 1.2 9.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat NTPase_1 PF03266.10 KFX91101.1 - 0.0063 16.2 0.0 2.7 7.6 0.0 2.9 3 0 0 3 3 3 1 NTPase ABC_tran PF00005.22 KFX91101.1 - 0.0082 16.4 0.0 0.11 12.7 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_5 PF07728.9 KFX91101.1 - 0.0087 15.7 0.0 0.21 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) KaiC PF06745.8 KFX91101.1 - 0.02 14.0 2.4 0.49 9.4 0.2 2.7 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.4 KFX91101.1 - 0.021 13.8 0.0 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KFX91101.1 - 0.021 13.7 0.0 0.96 8.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Ank_2 PF12796.2 KFX91101.1 - 0.021 15.1 0.0 0.072 13.4 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF87 PF01935.12 KFX91101.1 - 0.023 14.5 3.3 1.3 8.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 KFX91101.1 - 0.028 13.6 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zot PF05707.7 KFX91101.1 - 0.028 13.8 0.7 1.8 7.9 0.0 3.1 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) Miro PF08477.8 KFX91101.1 - 0.031 14.7 0.0 0.79 10.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 KFX91101.1 - 0.035 13.6 0.1 7.8 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFX91101.1 - 0.043 12.9 0.0 1.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.7 KFX91101.1 - 0.043 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KFX91101.1 - 0.045 13.1 0.0 12 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFX91101.1 - 0.11 12.1 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFX91101.1 - 0.12 12.2 1.5 7.8 6.3 0.0 3.1 4 0 0 4 4 2 0 AAA domain ATP_bind_1 PF03029.12 KFX91101.1 - 0.15 11.5 0.1 0.45 10.0 0.0 1.8 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein SUI1 PF01253.17 KFX91104.1 - 7.7e-29 99.3 6.3 1.4e-28 98.4 4.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 HERV-K_env_2 PF13804.1 KFX91105.1 - 0.14 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein Glyco_hydro_72 PF03198.9 KFX91115.1 - 3.3e-122 407.4 1.3 3.7e-122 407.2 0.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KFX91115.1 - 1.9e-06 27.0 0.0 3.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ribosomal_S7e PF01251.13 KFX91116.1 - 3.8e-82 274.3 0.1 4.3e-82 274.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e V_ATPase_I PF01496.14 KFX91122.1 - 1.8e-293 975.1 0.0 2.6e-293 974.6 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prenyltransf PF01255.14 KFX91122.1 - 1.4e-82 276.1 0.0 4.9e-82 274.3 0.0 1.9 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Filament PF00038.16 KFX91122.1 - 0.025 14.0 4.5 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Intermediate filament protein Transposase_22 PF02994.9 KFX91122.1 - 0.09 11.2 1.2 0.16 10.4 0.3 1.7 2 0 0 2 2 2 0 L1 transposable element IncA PF04156.9 KFX91122.1 - 0.2 11.2 4.5 0.14 11.7 0.7 2.2 2 0 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 KFX91122.1 - 0.25 11.1 1.3 3.9 7.2 0.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFX91122.1 - 0.33 10.0 1.7 4 6.5 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KFX91122.1 - 0.35 10.6 1.6 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Laminin Domain II DivIC PF04977.10 KFX91122.1 - 0.38 10.2 3.2 0.28 10.6 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.4 KFX91122.1 - 2.4 8.0 5.2 2.2 8.1 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NmrA PF05368.8 KFX91125.1 - 0.042 13.0 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Nucleos_tra2_C PF07662.8 KFX91126.1 - 2.1e-66 223.4 1.9 3.2e-66 222.7 1.3 1.3 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Thr_synth_N PF14821.1 KFX91126.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonine synthase N terminus ATP1G1_PLM_MAT8 PF02038.11 KFX91126.1 - 0.29 10.1 1.1 0.67 9.0 0.8 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF2569 PF10754.4 KFX91126.1 - 2.4 8.3 5.5 2.7 8.2 2.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) DUF668 PF05003.7 KFX91133.1 - 0.0089 16.2 5.8 0.59 10.3 0.5 2.6 1 1 0 2 2 2 2 Protein of unknown function (DUF668) GerPC PF10737.4 KFX91133.1 - 0.1 12.3 5.5 0.18 11.5 3.8 1.4 1 0 0 1 1 1 0 Spore germination protein GerPC eIF3_p135 PF12807.2 KFX91133.1 - 0.23 11.3 2.9 0.35 10.8 1.4 1.6 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Enterotoxin_ST PF02048.11 KFX91133.1 - 0.4 10.9 8.8 0.17 12.1 3.0 2.7 2 1 1 3 3 3 0 Heat-stable enterotoxin ST Aha1_N PF09229.6 KFX91133.1 - 0.51 10.1 12.0 0.86 9.4 3.4 2.5 1 1 1 2 2 2 0 Activator of Hsp90 ATPase, N-terminal DUF1456 PF07308.8 KFX91133.1 - 2.5 8.2 6.8 0.81 9.7 2.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Vps39_2 PF10367.4 KFX91133.1 - 7.3 6.8 7.8 3e+02 1.6 5.3 2.8 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 SWIRM PF04433.12 KFX91134.1 - 5.2e-12 45.7 0.1 4.2e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 KFX91134.1 - 1e-09 37.7 7.2 1.9e-09 36.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KFX91134.1 - 4.9e-08 32.9 0.1 1.7e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain CDP-OH_P_transf PF01066.16 KFX91135.1 - 2.5e-17 63.0 4.8 2.5e-17 63.0 3.3 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase adh_short PF00106.20 KFX91136.1 - 3.4e-16 59.6 0.1 9.8e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX91136.1 - 9.2e-08 32.1 0.2 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX91136.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 KFX91137.1 - 3.4e-14 53.0 1.3 2.6e-11 43.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX91137.1 - 8e-13 48.7 0.0 2.5e-12 47.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX91137.1 - 2e-08 34.5 0.1 6.7e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX91137.1 - 4.9e-06 25.6 0.2 0.00087 18.3 0.1 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KFX91137.1 - 0.0084 15.0 0.4 3.7 6.3 0.1 3.3 4 0 0 4 4 4 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX91137.1 - 0.068 12.9 0.2 8.1 6.1 0.0 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding DUF3425 PF11905.3 KFX91138.1 - 2.9e-29 101.6 0.9 4.8e-29 100.9 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ATPase_gene1 PF09527.5 KFX91139.1 - 0.12 12.1 2.8 0.3 10.9 0.7 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF2781 PF10914.3 KFX91140.1 - 1.6e-28 99.3 10.9 1.8e-28 99.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF1049 PF06305.6 KFX91141.1 - 0.016 14.7 0.7 0.016 14.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) LMWPc PF01451.16 KFX91146.1 - 8.1e-36 123.3 0.0 9.2e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Catalase PF00199.14 KFX91149.1 - 2.5e-149 497.1 3.7 2.8e-149 496.9 2.6 1.0 1 0 0 1 1 1 1 Catalase ECH PF00378.15 KFX91150.1 - 6.5e-64 215.3 0.1 9.3e-64 214.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Rer1 PF03248.8 KFX91151.1 - 5.5e-79 263.8 1.4 8.4e-79 263.2 1.0 1.3 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.8 KFX91151.1 - 2.7e-45 154.9 0.1 1.6e-44 152.4 0.1 1.9 1 1 0 1 1 1 1 Paf1 Arf PF00025.16 KFX91152.1 - 1.4e-73 245.8 0.0 1.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFX91152.1 - 6.5e-13 48.2 0.0 8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFX91152.1 - 1.3e-10 40.9 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFX91152.1 - 1.7e-10 40.1 1.4 1.1e-06 27.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFX91152.1 - 4.3e-09 35.8 0.0 5.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFX91152.1 - 4.2e-08 33.7 0.0 6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX91152.1 - 2.6e-06 27.3 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX91152.1 - 4.7e-05 22.9 0.0 0.0067 15.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFX91152.1 - 0.012 14.9 0.6 0.047 12.9 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 KFX91152.1 - 0.12 12.8 0.2 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 KFX91153.1 - 7.5e-22 77.2 0.0 5.9e-19 67.7 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KFX91153.1 - 0.029 12.9 0.1 0.54 8.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein DUF2114 PF09887.4 KFX91153.1 - 0.16 10.2 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) DbpA PF03880.10 KFX91155.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Cyto_heme_lyase PF01265.12 KFX91156.1 - 1.8e-48 165.3 0.1 3.3e-48 164.5 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Dehydrin PF00257.14 KFX91166.1 - 0.024 14.9 0.7 0.1 12.9 0.4 2.4 1 1 0 1 1 1 0 Dehydrin Sororin PF09666.5 KFX91166.1 - 0.027 14.6 2.2 0.091 12.9 1.5 1.9 1 0 0 1 1 1 0 Sororin protein Ten1 PF12658.2 KFX91167.1 - 9.3e-25 86.7 0.0 1.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 KFX91167.1 - 0.0012 18.4 0.0 0.0097 15.4 0.0 2.2 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Phosphoprotein PF00922.12 KFX91167.1 - 0.64 9.1 6.5 0.15 11.2 1.4 1.8 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Snf7 PF03357.16 KFX91168.1 - 3.2e-32 111.2 20.6 3.2e-32 111.2 14.3 2.0 1 1 1 2 2 2 1 Snf7 Allexi_40kDa PF05549.6 KFX91168.1 - 0.19 11.0 6.4 0.2 10.9 3.3 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein HET PF06985.6 KFX91168.1 - 0.8 9.8 6.1 1.5 8.9 4.2 1.8 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF3138 PF11336.3 KFX91168.1 - 1.8 6.6 6.7 1.3 7.0 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) BLOC1_2 PF10046.4 KFX91168.1 - 3.1 7.9 12.4 0.46 10.6 0.8 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Methyltransf_18 PF12847.2 KFX91169.1 - 8.5e-12 45.6 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX91169.1 - 1.6e-11 44.2 1.1 3.6e-11 43.0 0.8 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91169.1 - 1.1e-10 41.2 0.0 1.5e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX91169.1 - 1.6e-10 41.3 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX91169.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX91169.1 - 1.9e-09 37.8 0.0 3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX91169.1 - 5.4e-07 28.9 0.1 3.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFX91169.1 - 8.1e-07 29.0 0.0 2e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX91169.1 - 0.0055 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 KFX91169.1 - 0.024 14.0 0.1 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) BAF1_ABF1 PF04684.8 KFX91169.1 - 5.5 5.7 10.3 7.5 5.2 7.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FYVE PF01363.16 KFX91189.1 - 1.1e-20 73.2 29.7 1e-15 57.3 5.7 2.9 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KFX91189.1 - 0.00015 21.8 5.5 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KFX91189.1 - 0.00018 21.2 3.2 0.00018 21.2 2.2 3.7 5 1 0 5 5 5 2 AN1-like Zinc finger Rbsn PF11464.3 KFX91189.1 - 0.0085 15.6 0.0 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Flagellin_N PF00669.15 KFX91189.1 - 0.034 13.9 1.1 6.7 6.4 0.0 2.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region CK_II_beta PF01214.13 KFX91189.1 - 6.7 6.1 9.3 0.33 10.4 1.2 2.7 3 1 0 3 3 3 0 Casein kinase II regulatory subunit PKD_channel PF08016.7 KFX91191.1 - 7.7e-05 21.2 17.0 0.00074 18.0 11.8 2.1 1 1 0 1 1 1 1 Polycystin cation channel DUF4019 PF13211.1 KFX91191.1 - 0.056 13.7 0.2 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Whi5 PF08528.6 KFX91192.1 - 1.2e-08 34.3 0.0 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Asp PF00026.18 KFX91194.1 - 1.2e-65 221.8 7.1 1.5e-65 221.5 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KFX91194.1 - 0.00013 22.3 4.9 0.0046 17.4 1.4 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 KFX91194.1 - 0.00059 19.8 0.0 0.0044 16.9 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KFX91194.1 - 0.047 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease APH PF01636.18 KFX91195.1 - 1.3e-14 54.5 0.3 2.2e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX91195.1 - 0.066 12.5 0.0 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 RIO1 family WSC PF01822.14 KFX91196.1 - 2e-38 130.2 30.1 6e-20 70.9 6.1 2.8 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 KFX91196.1 - 2.5e-19 69.7 0.1 4.9e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Peroxidase SET PF00856.23 KFX91197.1 - 4.7e-14 53.0 0.0 1.9e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 SET domain TENA_THI-4 PF03070.11 KFX91207.1 - 3.1e-14 53.2 0.0 3.3e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Phos_pyr_kin PF08543.7 KFX91208.1 - 4.4e-82 274.9 1.8 6.8e-82 274.3 1.3 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KFX91208.1 - 7.5e-27 94.4 0.3 1.2e-26 93.8 0.2 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KFX91208.1 - 2e-07 30.4 0.3 3.1e-07 29.8 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 KFX91208.1 - 0.062 12.4 3.2 0.45 9.6 0.0 2.9 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family adh_short PF00106.20 KFX91209.1 - 2.1e-10 40.7 0.0 4.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91209.1 - 9.1e-06 25.4 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 KR domain LRR_4 PF12799.2 KFX91209.1 - 0.2 11.3 15.0 2.8 7.6 0.1 4.6 2 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Rad9 PF04139.8 KFX91210.1 - 1.4e-60 204.5 0.1 1.7e-60 204.2 0.1 1.0 1 0 0 1 1 1 1 Rad9 KH_1 PF00013.24 KFX91212.1 - 1.1e-36 124.2 13.7 5.1e-15 54.8 0.1 3.5 3 0 0 3 3 3 3 KH domain RabGAP-TBC PF00566.13 KFX91212.1 - 1.1e-34 119.8 0.1 2e-34 118.9 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain KH_3 PF13014.1 KFX91212.1 - 4.9e-28 96.2 14.0 1.5e-11 43.6 0.8 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFX91212.1 - 8.9e-08 31.5 9.8 0.057 12.9 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFX91212.1 - 5.5e-06 25.9 4.9 0.33 10.6 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFX91212.1 - 0.019 14.7 5.0 1.2 8.9 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain dUTPase PF00692.14 KFX91212.1 - 0.095 12.1 0.5 1.9 7.9 0.1 2.8 3 0 0 3 3 3 0 dUTPase DUF2247 PF10004.4 KFX91212.1 - 0.26 10.9 0.3 0.47 10.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) RRM_6 PF14259.1 KFX91219.1 - 3.5e-10 39.7 0.0 1.1e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX91219.1 - 1.1e-09 37.7 0.0 5.1e-07 29.2 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91219.1 - 1.2e-05 25.0 0.1 0.00032 20.4 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 KFX91219.1 - 0.057 12.3 1.2 0.078 11.8 0.9 1.1 1 0 0 1 1 1 0 AAR2 protein NMD3 PF04981.8 KFX91220.1 - 3.1e-71 239.2 1.7 5.6e-71 238.3 1.2 1.5 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 KFX91220.1 - 0.085 12.7 0.5 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 KFX91220.1 - 7.5 6.4 10.8 20 5.1 3.7 2.7 2 1 0 2 2 2 0 Double zinc ribbon UPF0086 PF01868.11 KFX91221.1 - 1.1e-25 89.0 0.1 1.7e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 EF-1_beta_acid PF10587.4 KFX91221.1 - 1 9.5 4.6 2.5 8.3 3.2 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Acyltransferase PF01553.16 KFX91222.1 - 1.1e-15 57.1 0.0 2.6e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase TPR_11 PF13414.1 KFX91223.1 - 2.6e-09 36.5 3.9 7.6e-09 35.0 1.7 2.2 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 KFX91223.1 - 0.0058 17.1 0.5 0.059 14.0 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX91223.1 - 0.013 15.8 0.1 0.036 14.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX91223.1 - 0.017 15.0 2.8 0.1 12.5 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX91223.1 - 0.038 14.1 0.4 0.074 13.1 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFX91223.1 - 0.19 11.3 5.7 0.37 10.4 0.4 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat CAP PF00188.21 KFX91223.1 - 0.3 11.5 2.2 1.1 9.8 0.2 2.1 1 1 1 2 2 2 0 Cysteine-rich secretory protein family Vfa1 PF08432.5 KFX91223.1 - 1.4 8.9 9.1 0.066 13.2 2.3 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HAD_2 PF13419.1 KFX91224.1 - 1.4e-15 57.9 0.0 2.5e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX91224.1 - 2e-08 34.8 0.0 6.8e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX91224.1 - 7.8e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 KFX91224.1 - 0.013 14.9 0.0 0.066 12.7 0.0 1.9 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Meleagrin PF08189.6 KFX91227.1 - 0.1 12.0 0.4 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family SET PF00856.23 KFX91231.1 - 8.1e-09 35.9 1.2 5.1e-07 30.1 0.4 2.4 2 0 0 2 2 2 2 SET domain Helicase_C PF00271.26 KFX91232.1 - 2.2e-07 30.6 0.0 6.2e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX91232.1 - 3.6e-06 26.5 0.2 1.7e-05 24.3 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFX91232.1 - 0.0056 16.5 0.0 0.093 12.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Dimer_Tnp_hAT PF05699.9 KFX91233.1 - 2.3e-17 62.3 0.0 5e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KFX91233.1 - 1.4e-06 28.1 0.3 4.2e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) RNase_T PF00929.19 KFX91234.1 - 0.00016 22.0 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Ank_2 PF12796.2 KFX91235.1 - 5.2e-25 87.6 0.6 1.6e-15 57.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX91235.1 - 5.1e-22 76.5 9.7 1.6e-08 33.9 0.5 6.3 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFX91235.1 - 5.3e-20 71.3 1.7 7.6e-08 32.6 0.2 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX91235.1 - 9.5e-18 63.8 5.0 2.2e-08 34.0 0.1 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX91235.1 - 2.4e-17 61.2 4.3 6.6e-05 22.7 0.1 6.2 5 1 0 5 5 5 4 Ankyrin repeat F-box-like PF12937.2 KFX91235.1 - 2.1e-05 24.1 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like CBFB_NFYA PF02045.10 KFX91239.1 - 1.2e-29 102.6 4.3 1.2e-29 102.6 3.0 2.4 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ORC6 PF05460.8 KFX91239.1 - 0.096 11.7 3.7 0.17 10.9 2.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ras PF00071.17 KFX91240.1 - 2.5e-40 137.5 0.0 2.7e-38 130.9 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFX91240.1 - 4.3e-17 62.7 0.0 5.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX91240.1 - 1.6e-10 40.4 0.0 2.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX91240.1 - 2.7e-05 23.4 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFX91240.1 - 0.012 15.5 0.1 0.039 13.9 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KFX91240.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KFX91240.1 - 0.036 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFX91240.1 - 0.038 13.9 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFX91240.1 - 0.045 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.1 KFX91240.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX91240.1 - 0.079 12.8 0.2 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFX91240.1 - 0.081 12.8 0.4 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFX91240.1 - 0.097 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Lys PF00062.15 KFX91241.1 - 0.00026 20.9 0.2 0.00035 20.5 0.1 1.2 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family F-box-like PF12937.2 KFX91242.1 - 0.00019 21.0 0.2 0.0013 18.4 0.1 2.4 2 0 0 2 2 2 1 F-box-like DAGK_cat PF00781.19 KFX91243.1 - 2.2e-08 33.6 0.2 3.1e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SWIB PF02201.13 KFX91244.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 SWIB/MDM2 domain Peptidase_S41 PF03572.13 KFX91245.1 - 2.7e-07 30.1 0.0 7e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 CDC73 PF05179.9 KFX91257.1 - 3e-22 79.2 0.0 8.2e-22 77.8 0.0 1.6 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family NAD_binding_5 PF07994.7 KFX91270.1 - 1.6e-112 375.8 0.2 2e-112 375.4 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KFX91270.1 - 2.9e-46 155.9 0.3 5.6e-46 154.9 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase polyprenyl_synt PF00348.12 KFX91271.1 - 8e-33 113.3 0.0 1.2e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KFX91271.1 - 3.8e-07 29.6 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain DUF3650 PF12368.3 KFX91271.1 - 0.03 13.8 0.4 0.08 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) PI-PLC-X PF00388.14 KFX91274.1 - 1.5e-58 196.3 0.1 2.5e-58 195.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFX91274.1 - 4.6e-39 133.0 0.1 1.4e-38 131.5 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KFX91274.1 - 1.3e-07 31.3 0.0 7.8e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 KFX91274.1 - 0.0033 17.4 0.2 0.0094 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF328 PF03883.9 KFX91274.1 - 0.061 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF328) Oxidored_molyb PF00174.14 KFX91276.1 - 1e-40 138.8 0.0 1.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KFX91276.1 - 1.9e-30 105.1 0.7 3.2e-30 104.4 0.5 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain DoxA PF07680.6 KFX91276.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 TQO small subunit DoxA Cytochrom_C_asm PF01578.15 KFX91285.1 - 0.014 14.9 0.5 0.022 14.3 0.1 1.5 2 0 0 2 2 2 0 Cytochrome C assembly protein MARVEL PF01284.18 KFX91285.1 - 0.051 13.3 2.2 0.21 11.3 1.5 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF1404 PF07185.6 KFX91285.1 - 2.5 7.6 6.5 39 3.7 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1404) zf-C2H2_jaz PF12171.3 KFX91291.1 - 0.00025 21.1 0.3 0.35 11.0 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KFX91291.1 - 0.00086 19.5 20.6 0.031 14.6 0.6 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KFX91291.1 - 0.013 15.6 0.2 0.22 11.6 0.0 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFX91291.1 - 0.035 14.3 3.2 0.49 10.6 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-DNA_Pol PF08996.5 KFX91291.1 - 0.21 10.9 1.9 0.42 9.9 1.3 1.4 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2_4 PF13894.1 KFX91291.1 - 0.24 11.8 20.2 0.51 10.7 0.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFX91291.1 - 1.1 9.2 5.9 2 8.4 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4066 PF13278.1 KFX91292.1 - 1.6e-25 89.2 0.0 2.6e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX91292.1 - 3e-13 49.4 0.0 4.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.1 KFX91294.1 - 3.2e-07 30.1 0.8 0.13 12.1 0.1 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX91294.1 - 0.00014 21.4 3.2 0.38 10.4 0.0 3.9 3 1 0 3 3 3 2 TPR repeat Apc3 PF12895.2 KFX91294.1 - 0.0013 18.8 0.5 0.0042 17.2 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFX91294.1 - 0.32 11.0 6.4 11 6.1 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Cyt-b5 PF00173.23 KFX91295.1 - 6.5e-05 22.6 0.0 8.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KFX91296.1 - 3.2e-47 161.1 0.0 3.9e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX91296.1 - 0.00067 19.7 0.0 0.024 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX91296.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX91296.1 - 0.057 13.1 0.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFX91297.1 - 4.9e-76 256.0 0.0 6.9e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF92 PF01940.11 KFX91297.1 - 2.7e-63 213.1 3.9 2.7e-63 213.1 2.7 1.6 2 0 0 2 2 2 1 Integral membrane protein DUF92 Pyr_redox_3 PF13738.1 KFX91297.1 - 3.3e-06 27.2 0.0 8.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX91297.1 - 0.00015 20.8 0.1 0.049 12.5 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX91297.1 - 0.032 14.1 0.0 0.091 12.6 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX91297.1 - 0.071 12.1 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KFX91297.1 - 0.081 13.3 0.4 28 5.2 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KFX91297.1 - 0.14 10.9 0.0 0.66 8.7 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Vfa1 PF08432.5 KFX91297.1 - 2.2 8.2 6.4 3.9 7.4 4.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAGA-Tad1 PF12767.2 KFX91298.1 - 2e-55 188.1 0.0 2.6e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 KFX91299.1 - 5.7e-120 401.1 0.0 7e-120 400.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3921 PF13060.1 KFX91299.1 - 0.005 16.6 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3921) WD40 PF00400.27 KFX91300.1 - 8.9e-51 168.0 22.2 2e-08 33.7 0.2 10.6 10 0 0 10 10 10 10 WD domain, G-beta repeat eIF2A PF08662.6 KFX91300.1 - 5.1e-05 23.0 3.2 1 9.0 0.0 4.5 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KFX91300.1 - 0.0018 17.4 3.2 2.7 7.0 0.0 4.7 4 2 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KFX91300.1 - 0.026 14.2 0.6 5.7 6.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 KFX91300.1 - 0.28 10.8 3.4 0.91 9.2 0.5 2.9 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term p450 PF00067.17 KFX91306.1 - 3.8e-62 210.3 0.0 4.9e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_GPO PF05929.6 KFX91306.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase p450 PF00067.17 KFX91307.1 - 6.2e-68 229.4 0.0 6.1e-67 226.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 KFX91308.1 - 2.1e-33 115.6 2.8 3.3e-33 115.0 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_3 PF01494.14 KFX91308.1 - 5.9e-13 48.6 0.1 1.9e-12 46.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFX91308.1 - 8.7e-07 28.3 0.5 0.00099 18.2 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFX91308.1 - 3.7e-05 22.8 0.0 8.3e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein CBM_1 PF00734.13 KFX91308.1 - 0.00012 21.6 9.1 0.00029 20.4 6.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain NAD_binding_8 PF13450.1 KFX91308.1 - 0.00049 20.0 0.0 0.0021 18.0 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX91308.1 - 0.00072 18.5 0.6 0.72 8.6 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HTH_Tnp_Tc3_2 PF01498.13 KFX91308.1 - 0.17 11.9 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Transposase Pyr_redox PF00070.22 KFX91308.1 - 0.19 12.1 4.1 0.26 11.7 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2204 PF09970.4 KFX91308.1 - 0.41 10.0 0.0 0.7 9.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) Isochorismatase PF00857.15 KFX91309.1 - 1.6e-18 67.2 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 KFX91309.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Pyr_redox PF00070.22 KFX91310.1 - 1.7e-11 44.3 0.0 3.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX91310.1 - 2.9e-07 30.5 0.1 0.013 15.3 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX91310.1 - 1e-05 24.6 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFX91310.1 - 2.8e-05 24.2 0.0 6.4e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX91310.1 - 0.0043 16.4 0.0 0.0087 15.5 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KFX91310.1 - 0.033 13.0 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX91310.1 - 0.038 13.7 0.0 5 6.8 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KFX91310.1 - 0.052 12.1 0.1 5.2 5.5 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase Fungal_trans_2 PF11951.3 KFX91311.1 - 7.3e-36 123.5 3.9 9.9e-36 123.1 2.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91311.1 - 1.1e-05 25.1 7.8 2.1e-05 24.2 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABM PF03992.11 KFX91312.1 - 0.0021 18.0 0.1 0.0028 17.6 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Epimerase PF01370.16 KFX91313.1 - 6.1e-14 52.0 0.2 1.5e-12 47.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX91313.1 - 9.7e-05 22.4 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFX91313.1 - 0.0001 21.4 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KFX91313.1 - 0.00012 21.4 0.1 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KFX91313.1 - 0.012 14.5 1.0 0.75 8.6 0.0 2.5 1 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 KFX91313.1 - 0.025 13.4 0.1 0.91 8.3 0.0 2.6 2 1 1 3 3 3 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFX91313.1 - 0.047 12.3 0.0 0.077 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFX91313.1 - 0.097 12.9 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TPR_11 PF13414.1 KFX91314.1 - 4.8e-11 42.1 11.6 0.0001 21.8 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KFX91314.1 - 2.1e-09 36.5 13.0 0.0092 15.8 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFX91314.1 - 1.8e-06 27.8 8.6 0.0052 16.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX91314.1 - 7.5e-06 25.3 7.3 0.29 10.8 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX91314.1 - 0.00023 21.4 12.2 0.47 11.2 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX91314.1 - 0.0016 18.7 9.9 0.22 11.8 0.4 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFX91314.1 - 0.0033 17.7 5.2 0.42 11.1 1.5 4.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX91314.1 - 0.04 13.7 2.2 2.1 8.3 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX91314.1 - 0.082 13.6 22.5 0.88 10.3 0.2 6.3 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX91314.1 - 0.13 12.1 2.3 5.8 6.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1469 PF07332.6 KFX91315.1 - 4.8 6.9 10.9 1.5 8.6 1.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) O-FucT PF10250.4 KFX91318.1 - 0.0023 17.0 0.0 0.0029 16.7 0.0 1.0 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Transaldolase PF00923.14 KFX91319.1 - 3.8e-95 318.3 0.5 4.3e-95 318.1 0.3 1.0 1 0 0 1 1 1 1 Transaldolase ketoacyl-synt PF00109.21 KFX91334.1 - 8.5e-18 64.7 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 KFX91334.1 - 1.3e-16 60.4 0.0 2.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KFX91334.1 - 1.5e-10 40.9 0.3 5.3e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFX91334.1 - 6.3e-05 22.9 0.3 0.00018 21.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase GATase PF00117.23 KFX91335.1 - 7.9e-31 107.0 0.0 9.3e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFX91335.1 - 9.2e-08 31.7 0.1 5.8e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 Sporozoite_P67 PF05642.6 KFX91337.1 - 0.54 8.0 8.3 0.57 7.9 5.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box PF00646.28 KFX91350.1 - 1.7e-07 30.7 0.1 3.7e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX91350.1 - 1.3e-05 24.8 0.2 5.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 KFX91354.1 - 1.2e-15 56.7 1.6 0.0007 19.3 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Peptidase_M20 PF01546.23 KFX91354.1 - 2e-15 56.8 0.0 3.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX91354.1 - 5.9e-07 29.2 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Tim17 PF02466.14 KFX91355.1 - 3.7e-34 117.5 7.2 4.6e-34 117.2 5.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 KFX91355.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal PPI_Ypi1 PF07491.6 KFX91357.1 - 0.0044 16.6 4.5 0.016 14.8 3.0 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor Ribonuc_L-PSP PF01042.16 KFX91358.1 - 7.5e-39 132.2 0.0 8.4e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DDE_Tnp_4 PF13359.1 KFX91358.1 - 0.091 12.3 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Ribosomal_L14 PF00238.14 KFX91359.1 - 3e-32 110.9 0.0 3.3e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 KFX91360.1 - 2e-78 263.8 0.0 3.2e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 KFX91361.1 - 3e-35 120.3 0.0 6e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFX91361.1 - 3.9e-27 94.6 1.1 1.1e-26 93.1 0.8 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFX91361.1 - 8e-09 35.0 0.0 1.6e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PTR2 PF00854.16 KFX91362.1 - 1.9e-43 148.7 13.2 2.1e-42 145.2 9.2 2.2 1 1 0 1 1 1 1 POT family Rod_cone_degen PF15201.1 KFX91362.1 - 0.0044 16.8 0.1 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 Progressive rod-cone degeneration Aldedh PF00171.17 KFX91363.1 - 9.6e-136 452.7 1.3 1.1e-135 452.5 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX91363.1 - 0.0021 16.8 0.0 0.0046 15.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Glyco_hydro_18 PF00704.23 KFX91366.1 - 8.7e-19 68.1 2.0 1.3e-17 64.3 1.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF946 PF06101.6 KFX91367.1 - 1.6e-05 23.1 0.0 2.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Kp4 PF09044.5 KFX91370.1 - 5.9e-30 103.7 2.0 7.6e-30 103.3 1.4 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.1 KFX91370.1 - 0.043 14.2 1.1 0.056 13.9 0.8 1.3 1 0 0 1 1 1 0 Meiotically up-regulated gene family GST_N_3 PF13417.1 KFX91371.1 - 1e-09 38.4 0.1 2.3e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX91371.1 - 2.3e-05 24.3 0.1 4.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 KFX91371.1 - 0.5 10.3 5.2 0.092 12.6 0.5 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX91376.1 - 9e-88 294.8 17.8 1.1e-87 294.5 12.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91376.1 - 8e-24 83.9 17.2 8e-24 83.9 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Granulin PF00396.13 KFX91377.1 - 8.2 6.6 20.3 12 6.0 4.5 2.6 1 1 1 2 2 2 0 Granulin SHR3_chaperone PF08229.6 KFX91378.1 - 1.3e-71 239.6 0.0 1.5e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 IBN_N PF03810.14 KFX91382.1 - 4.9e-12 45.5 0.2 3.7e-10 39.5 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 KFX91382.1 - 6.1e-05 21.7 0.2 0.00016 20.3 0.1 1.7 1 1 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 KFX91382.1 - 0.00013 22.1 2.3 0.39 11.0 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Xpo1 PF08389.7 KFX91382.1 - 0.0027 17.6 4.3 3.6 7.4 0.0 5.1 7 0 0 7 7 7 1 Exportin 1-like protein DUF2435 PF10363.4 KFX91382.1 - 0.01 15.7 0.5 0.051 13.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 KFX91382.1 - 0.074 13.4 1.6 3.5 8.0 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region MFS_1 PF07690.11 KFX91385.1 - 7.2e-41 140.0 96.1 1.9e-37 128.8 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KFX91386.1 - 1.8e-15 57.0 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX91386.1 - 4.9e-13 48.4 0.0 6.5e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX91386.1 - 7.4e-11 42.3 0.5 1.7e-10 41.2 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX91386.1 - 5e-09 35.4 0.1 3.5e-08 32.7 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFX91386.1 - 1.9e-07 31.1 0.5 3.8e-07 30.1 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX91386.1 - 2.6e-05 23.2 0.1 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFX91386.1 - 0.00063 19.0 0.2 0.00094 18.5 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KFX91386.1 - 0.003 17.2 1.1 0.013 15.1 0.7 2.3 1 1 0 1 1 1 1 KR domain FMN_dh PF01070.13 KFX91387.1 - 4.6e-103 344.8 0.0 5.8e-103 344.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFX91387.1 - 1.6e-20 72.6 0.0 3.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KFX91387.1 - 2.2e-05 23.5 0.0 0.00083 18.3 0.0 2.8 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFX91387.1 - 8.5e-05 21.6 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 KFX91387.1 - 0.063 12.7 0.2 0.097 12.1 0.1 1.2 1 0 0 1 1 1 0 ATP11 protein 2-Hacid_dh_C PF02826.14 KFX91388.1 - 5.4e-55 185.2 0.0 7.1e-55 184.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX91388.1 - 1.6e-21 76.1 0.0 1.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX91388.1 - 0.00092 19.0 0.0 0.0021 17.9 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX91388.1 - 0.022 15.1 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 KFX91388.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans PF04082.13 KFX91389.1 - 3.3e-13 49.1 0.0 9e-13 47.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91389.1 - 4.1e-07 29.8 7.4 7.3e-07 28.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX91390.1 - 3.4e-29 101.9 0.3 6.9e-29 100.8 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX91390.1 - 3.8e-16 59.5 0.0 5.1e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX91390.1 - 7.4e-13 48.5 0.2 1.2e-12 47.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX91390.1 - 1.3e-05 24.7 0.0 3.6e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFX91390.1 - 0.0069 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KFX91390.1 - 0.023 13.9 0.1 0.037 13.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_N PF08240.7 KFX91391.1 - 1.3e-27 95.6 0.5 2.4e-27 94.8 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX91391.1 - 5.9e-19 67.8 0.2 1e-18 67.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFX91391.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TP_methylase PF00590.15 KFX91391.1 - 0.071 12.8 0.7 0.74 9.4 0.1 2.0 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_8 PF13450.1 KFX91391.1 - 0.13 12.2 0.2 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TT_ORF2 PF02957.10 KFX91392.1 - 0.074 13.7 0.7 0.074 13.7 0.5 1.4 1 1 0 1 1 1 0 TT viral ORF2 Dynamin_N PF00350.18 KFX91396.1 - 1.5e-11 44.4 0.0 7.2e-11 42.1 0.0 2.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KFX91396.1 - 9.2e-06 25.6 0.0 0.0098 15.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KFX91396.1 - 8.9e-05 21.7 0.3 0.0012 18.0 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 IIGP PF05049.8 KFX91396.1 - 0.00026 19.9 0.0 0.00096 18.0 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 KFX91396.1 - 0.00027 21.2 0.2 0.0034 17.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 KFX91396.1 - 0.0016 18.4 0.1 0.0095 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KFX91396.1 - 0.022 15.2 0.0 0.071 13.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 KFX91396.1 - 0.06 12.3 0.3 0.24 10.3 0.0 2.0 2 0 0 2 2 2 0 Septin ABC2_membrane_2 PF12679.2 KFX91397.1 - 3.4 6.4 8.4 4.7 5.9 5.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RRM_6 PF14259.1 KFX91398.1 - 2.8e-08 33.6 0.1 1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX91398.1 - 4.2e-07 29.5 0.0 1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91398.1 - 0.00042 20.1 0.0 0.00099 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 KFX91398.1 - 0.0046 17.0 3.0 0.021 14.9 2.1 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFX91398.1 - 0.0054 16.9 20.8 0.99 9.8 2.6 5.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX91398.1 - 0.0067 16.6 0.3 0.0067 16.6 0.2 3.8 3 0 0 3 3 3 1 Zinc-finger double domain NTP_transf_3 PF12804.2 KFX91398.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain zf-CHCC PF10276.4 KFX91398.1 - 0.13 12.1 4.6 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger domain FliJ PF02050.11 KFX91398.1 - 0.19 11.7 7.2 7.8 6.5 2.0 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein zf-C2H2 PF00096.21 KFX91398.1 - 1.5 9.2 24.8 1.9 9.0 1.9 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type CG-1 PF03859.11 KFX91403.1 - 0.0069 15.9 0.8 0.0099 15.4 0.5 1.2 1 0 0 1 1 1 1 CG-1 domain Ribosomal_S13 PF00416.17 KFX91404.1 - 3.1e-41 140.1 1.6 3.7e-41 139.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KFX91404.1 - 0.0022 16.5 0.0 0.0029 16.2 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 KFX91404.1 - 0.088 12.8 0.2 0.34 10.9 0.0 2.0 1 1 0 2 2 2 0 Helix-hairpin-helix motif SBDS_C PF09377.5 KFX91405.1 - 2.6e-48 162.8 0.2 4.6e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KFX91405.1 - 1e-30 105.3 1.8 1.9e-30 104.4 1.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 KFX91406.1 - 1.4e-128 429.5 0.9 1.8e-128 429.2 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KFX91406.1 - 6.9e-10 39.0 0.1 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_L13e PF01294.13 KFX91407.1 - 3.8e-64 215.4 6.6 5e-64 215.0 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Hormone_2 PF00123.15 KFX91407.1 - 0.15 11.8 1.6 0.32 10.8 1.1 1.5 1 0 0 1 1 1 0 Peptide hormone Amidoligase_2 PF12224.3 KFX91408.1 - 2.7e-29 102.5 0.0 3.6e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Abhydrolase_4 PF08386.5 KFX91409.1 - 4.3e-20 71.5 0.0 7.5e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KFX91409.1 - 4.7e-17 62.3 0.0 2e-16 60.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX91409.1 - 7.2e-08 32.5 0.0 1.1e-06 28.7 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FA_hydroxylase PF04116.8 KFX91410.1 - 7.2e-15 55.3 14.1 7.2e-15 55.3 9.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Hexapep PF00132.19 KFX91411.1 - 9e-18 62.9 17.0 2.4e-12 45.7 3.2 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX91411.1 - 3.4e-16 58.4 8.0 1.4e-09 37.3 3.4 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KFX91411.1 - 4.5e-06 26.5 0.1 7.6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Glyco_hydro_1 PF00232.13 KFX91412.1 - 1.4e-102 343.2 0.0 1.7e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TruD PF01142.13 KFX91413.1 - 3.4e-52 177.3 10.1 5.2e-50 170.1 0.0 4.5 4 0 0 4 4 4 2 tRNA pseudouridine synthase D (TruD) SAD_SRA PF02182.12 KFX91413.1 - 0.026 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 SAD/SRA domain DUF4146 PF13652.1 KFX91413.1 - 0.048 13.4 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) Ycf1 PF05758.7 KFX91413.1 - 0.89 7.1 9.0 3.1 5.3 1.8 2.4 2 0 0 2 2 2 0 Ycf1 PLA2_B PF01735.13 KFX91418.1 - 1.3e-196 653.5 1.3 1.5e-196 653.3 0.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Cupin_2 PF07883.6 KFX91419.1 - 9.2e-05 21.8 0.1 0.0017 17.8 0.1 2.3 1 1 0 1 1 1 1 Cupin domain AT_hook PF02178.14 KFX91420.1 - 0.91 9.4 14.4 1.1 9.1 0.2 4.3 3 0 0 3 3 3 0 AT hook motif adh_short PF00106.20 KFX91421.1 - 2.4e-17 63.3 0.2 8.9e-17 61.5 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91421.1 - 1.1e-08 34.9 0.2 3.3e-08 33.3 0.3 1.7 2 0 0 2 2 2 1 KR domain DUF3073 PF11273.3 KFX91421.1 - 0.14 12.7 0.0 0.34 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) DUF3425 PF11905.3 KFX91422.1 - 8.4e-21 74.2 2.4 1.8e-20 73.2 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.13 KFX91423.1 - 3.5e-27 94.9 2.2 5.2e-27 94.3 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91423.1 - 3.8e-08 33.1 4.3 8.2e-08 32.0 3.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX91424.1 - 1.5e-38 132.3 27.9 1.5e-38 132.3 19.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX91424.1 - 7.4e-06 24.4 1.8 1.1e-05 23.8 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) bZIP_1 PF00170.16 KFX91425.1 - 5.3e-06 26.2 5.5 8e-06 25.7 3.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX91425.1 - 0.0015 18.2 6.1 0.0024 17.6 4.2 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFX91425.1 - 0.14 12.4 9.0 0.23 11.7 6.0 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor DJ-1_PfpI PF01965.19 KFX91426.1 - 1.1e-17 63.9 0.1 1.8e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KFX91426.1 - 0.00046 19.6 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Sugar_tr PF00083.19 KFX91426.1 - 0.0094 14.5 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.20 KFX91427.1 - 1.6e-27 96.4 0.0 2.1e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91427.1 - 1.3e-13 51.0 0.0 1.7e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFX91427.1 - 3.9e-06 26.9 0.0 9.1e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 KFX91427.1 - 1.5e-05 24.9 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 KFX91427.1 - 2.4e-05 24.6 0.1 5.1e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KFX91427.1 - 0.0005 19.5 0.0 0.00063 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KFX91427.1 - 0.00051 19.1 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KFX91427.1 - 0.0007 18.5 0.1 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KFX91427.1 - 0.0028 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 KFX91427.1 - 0.0045 16.8 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KFX91427.1 - 0.017 14.7 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KFX91427.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 KFX91427.1 - 0.056 12.8 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KFX91427.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 KFX91427.1 - 0.2 10.5 0.7 2.5 6.9 0.2 2.1 2 0 0 2 2 2 0 Male sterility protein Methyltransf_2 PF00891.13 KFX91428.1 - 4.3e-23 81.7 0.0 1e-22 80.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Ras PF00071.17 KFX91429.1 - 5.6e-05 22.5 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Dynactin_p22 PF07426.6 KFX91430.1 - 0.041 13.1 1.6 0.11 11.7 1.1 1.7 1 0 0 1 1 1 0 Dynactin subunit p22 WW PF00397.21 KFX91430.1 - 0.24 11.3 5.9 0.58 10.0 4.1 1.7 1 0 0 1 1 1 0 WW domain LMBR1 PF04791.11 KFX91430.1 - 0.7 8.4 0.0 1.3 7.5 0.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein UbiA PF01040.13 KFX91431.1 - 5.8e-34 117.4 23.8 8.9e-34 116.8 16.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Myb_DNA-bind_6 PF13921.1 KFX91432.1 - 5.7e-07 29.5 0.3 3.1e-06 27.1 0.1 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Minor_capsid_2 PF11114.3 KFX91432.1 - 0.19 11.6 5.1 0.81 9.5 0.1 2.4 2 0 0 2 2 2 0 Minor capsid protein Ferric_reduct PF01794.14 KFX91435.1 - 9.1e-12 45.1 5.1 9.1e-12 45.1 3.5 1.7 1 1 0 1 1 1 1 Ferric reductase like transmembrane component DUF485 PF04341.7 KFX91435.1 - 0.22 11.2 4.6 0.26 11.0 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 CTP_transf_2 PF01467.21 KFX91440.1 - 2.9e-22 79.4 0.0 4.7e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase NOC3p PF07540.6 KFX91441.1 - 1.6e-33 114.8 0.4 5.4e-33 113.1 0.3 2.0 1 0 0 1 1 1 1 Nucleolar complex-associated protein Trypan_PARP PF05887.6 KFX91441.1 - 0.0095 15.7 9.2 0.021 14.6 6.4 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) malic PF00390.14 KFX91444.1 - 6.6e-72 240.8 0.0 1e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 KFX91444.1 - 2e-47 161.9 0.1 4e-47 160.9 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 KFX91444.1 - 0.066 12.7 0.5 0.22 11.1 0.1 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M18 PF02127.10 KFX91452.1 - 7.1e-155 515.7 0.0 1.3e-154 514.9 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) OSCP PF00213.13 KFX91452.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Methyltransf_16 PF10294.4 KFX91453.1 - 4.6e-18 65.2 0.0 6.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX91453.1 - 3.8e-11 43.5 0.0 7.6e-11 42.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX91453.1 - 9.4e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX91453.1 - 0.00099 18.5 0.0 0.0042 16.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX91453.1 - 0.0023 17.9 0.2 0.01 15.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX91453.1 - 0.0039 16.3 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KFX91453.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KFX91453.1 - 0.014 14.9 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFX91453.1 - 0.025 15.0 0.0 0.079 13.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KFX91453.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2894 PF11445.3 KFX91456.1 - 4.6 7.4 7.9 6 7.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Vfa1 PF08432.5 KFX91456.1 - 9.2 6.2 10.6 12 5.8 7.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Glyco_transf_28 PF03033.15 KFX91457.1 - 4.6e-20 71.7 0.2 8.5e-19 67.7 0.2 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX91457.1 - 2e-05 23.3 0.0 3.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KFX91457.1 - 0.00045 20.3 0.0 0.0022 18.1 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 KFX91457.1 - 0.0014 18.3 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 KFX91457.1 - 0.87 9.3 5.9 0.65 9.7 0.3 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Sugar_tr PF00083.19 KFX91459.1 - 3.6e-75 253.2 21.6 4.4e-75 252.9 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91459.1 - 5.6e-33 114.1 52.3 3.2e-31 108.3 18.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX91459.1 - 1.6e-07 30.0 21.9 3e-07 29.2 0.2 3.1 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX91459.1 - 4.5e-06 25.1 9.8 5.4e-06 24.8 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.7 KFX91459.1 - 0.0023 17.1 0.2 0.0023 17.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF554) MFS_1 PF07690.11 KFX91460.1 - 1.9e-33 115.6 72.5 8.5e-30 103.6 37.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.1 KFX91461.1 - 9.1e-15 55.1 0.2 1.7e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX91461.1 - 1.6e-14 53.8 0.3 8.6e-14 51.5 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX91461.1 - 1e-11 44.1 0.0 1.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX91461.1 - 6.3e-07 29.4 0.3 3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KFX91461.1 - 8.5e-06 25.1 0.0 1.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KFX91461.1 - 8.8e-06 24.8 0.0 1.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFX91461.1 - 0.0051 15.7 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KFX91461.1 - 0.0088 15.7 0.4 0.069 12.8 0.3 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KFX91461.1 - 0.018 13.9 0.1 0.32 9.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.13 KFX91462.1 - 1.9e-13 49.9 0.0 3.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91462.1 - 9.9e-07 28.5 12.8 1.8e-06 27.7 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.9 KFX91463.1 - 1.7e-44 152.2 0.0 2.2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 KFX91464.1 - 4.9e-54 183.4 0.4 5.5e-54 183.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HpaB PF03241.8 KFX91464.1 - 0.083 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Epimerase PF01370.16 KFX91465.1 - 4.5e-11 42.6 0.1 7.4e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX91465.1 - 3.9e-07 29.5 0.6 6.6e-07 28.8 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX91465.1 - 2.5e-06 27.6 0.5 4e-06 26.9 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX91465.1 - 1.6e-05 25.2 0.1 3.7e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFX91465.1 - 0.0001 21.1 0.1 0.025 13.2 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX91465.1 - 0.00011 21.1 0.1 0.0029 16.5 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 KFX91465.1 - 0.0061 16.4 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX91465.1 - 0.013 14.3 0.1 0.046 12.6 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 KFX91465.1 - 0.016 15.1 0.4 0.047 13.6 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans_2 PF11951.3 KFX91466.1 - 0.00028 19.5 0.0 0.1 11.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pkinase PF00069.20 KFX91467.1 - 5.7e-25 87.9 0.3 1e-12 47.7 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91467.1 - 1.2e-07 31.1 0.1 0.012 14.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX91467.1 - 0.16 10.7 0.2 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase OstA_2 PF13100.1 KFX91475.1 - 0.024 13.9 0.6 5.1 6.3 0.0 2.3 2 0 0 2 2 2 0 OstA-like protein TPR_12 PF13424.1 KFX91477.1 - 4.1e-06 26.6 8.7 0.0059 16.5 0.7 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX91477.1 - 0.0026 17.5 0.8 1.5 8.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX91477.1 - 0.0031 17.1 0.8 1.4 8.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX91477.1 - 0.02 14.5 2.6 0.29 10.8 1.1 2.6 1 1 1 2 2 2 0 TPR repeat TPR_14 PF13428.1 KFX91477.1 - 0.027 15.0 0.3 8.3 7.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX91477.1 - 0.042 13.9 0.5 0.14 12.3 0.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Utp14 PF04615.8 KFX91478.1 - 0.24 9.4 0.8 0.35 8.9 0.6 1.2 1 0 0 1 1 1 0 Utp14 protein Esterase_phd PF10503.4 KFX91479.1 - 6.6e-23 81.0 1.3 2.9e-22 79.0 0.9 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX91479.1 - 3.4e-14 52.5 1.8 4.6e-14 52.1 1.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX91479.1 - 2.8e-05 23.9 0.3 4.1e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX91479.1 - 0.00022 21.1 1.5 0.0011 18.9 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX91479.1 - 0.00069 18.4 1.9 0.0024 16.6 1.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family adh_short PF00106.20 KFX91480.1 - 5.2e-24 85.0 4.4 6.4e-24 84.7 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX91480.1 - 1.4e-20 74.0 0.1 1.7e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX91480.1 - 1.3e-12 47.7 1.6 1.8e-12 47.3 1.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 KFX91480.1 - 0.0079 16.0 0.4 0.14 11.9 0.2 2.1 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 KFX91480.1 - 0.02 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_Tnp_Tc5 PF03221.11 KFX91493.1 - 3.8e-06 26.6 0.2 8.1e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.11 KFX91493.1 - 0.0049 16.1 0.1 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 KFX91493.1 - 0.038 13.6 0.0 0.22 11.2 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain DUF1013 PF06242.6 KFX91493.1 - 0.052 13.5 0.4 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) HTH_Tnp_4 PF13613.1 KFX91493.1 - 0.052 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CENP-B_N PF04218.8 KFX91493.1 - 0.096 12.1 1.1 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.2 KFX91493.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 KFX91493.1 - 0.12 12.1 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain PAP_assoc PF03828.14 KFX91497.1 - 2.5e-19 68.9 0.1 5.3e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFX91497.1 - 7.3e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Sel1 PF08238.7 KFX91500.1 - 1.8e-13 50.6 21.9 7.2e-07 29.6 0.1 7.5 7 0 0 7 7 7 6 Sel1 repeat TBPIP PF07106.8 KFX91501.1 - 5e-30 104.2 0.0 6.3e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 KFX91501.1 - 0.0026 17.4 0.1 0.0046 16.6 0.1 1.4 1 1 0 1 1 1 1 Mnd1 family SHOCT PF09851.4 KFX91501.1 - 0.045 13.2 2.5 5.2 6.6 0.1 3.0 3 0 0 3 3 3 0 Short C-terminal domain SPOC PF07744.8 KFX91504.1 - 2.6e-18 66.6 0.0 8.3e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 KFX91504.1 - 7.8e-15 54.9 3.1 1.7e-14 53.8 2.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KFX91504.1 - 2.7e-09 36.5 9.8 4.9e-09 35.7 6.8 1.4 1 0 0 1 1 1 1 PHD-finger SKG6 PF08693.5 KFX91504.1 - 0.017 14.3 2.4 0.038 13.3 1.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PDGLE PF13190.1 KFX91504.1 - 0.033 13.8 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 PDGLE domain Phage_Coat_B PF05356.6 KFX91504.1 - 0.1 12.3 0.6 0.23 11.1 0.4 1.5 1 0 0 1 1 1 0 Phage Coat protein B PHD_2 PF13831.1 KFX91504.1 - 1.5 8.2 5.0 2.8 7.3 3.5 1.5 1 0 0 1 1 1 0 PHD-finger Kelch_5 PF13854.1 KFX91504.1 - 9.7 6.2 11.5 0.26 11.3 0.2 3.6 4 0 0 4 4 4 0 Kelch motif zf-C2H2_jaz PF12171.3 KFX91505.1 - 2.6e-06 27.4 0.0 4.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX91505.1 - 0.00028 20.9 0.1 0.00048 20.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFX91505.1 - 0.063 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Cwf_Cwc_15 PF04889.7 KFX91505.1 - 1.9 8.1 25.8 3.6 7.2 1.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Striatin PF08232.7 KFX91505.1 - 9.6 6.5 12.9 15 5.8 3.8 2.9 2 0 0 2 2 2 0 Striatin family FF PF01846.14 KFX91506.1 - 2.1e-09 37.1 2.9 2.9e-07 30.3 0.0 3.0 3 0 0 3 3 3 1 FF domain WW PF00397.21 KFX91506.1 - 7.1e-09 35.3 4.9 1.7e-08 34.1 3.4 1.7 1 0 0 1 1 1 1 WW domain Di19_C PF14571.1 KFX91506.1 - 0.11 12.8 0.2 0.11 12.8 0.2 3.3 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal DDHD PF02862.12 KFX91506.1 - 4 7.1 7.1 2.3 7.9 1.1 2.3 2 0 0 2 2 2 0 DDHD domain Proteasome PF00227.21 KFX91507.1 - 1.3e-59 200.6 0.2 1.7e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX91507.1 - 2.8e-14 52.0 0.2 7.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KFX91507.1 - 0.057 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.16 KFX91508.1 - 2.3e-20 72.5 1.4 2.3e-20 72.5 1.0 1.9 2 1 0 2 2 2 1 PAP2 superfamily DUF350 PF03994.9 KFX91508.1 - 0.13 11.9 0.3 0.13 11.9 0.2 2.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF350) RseC_MucC PF04246.7 KFX91508.1 - 1.4 8.4 5.7 0.28 10.7 0.2 2.4 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Med7 PF05983.6 KFX91509.1 - 2.1e-58 196.7 0.0 2.5e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 MED7 protein DUF747 PF05346.6 KFX91510.1 - 8.6e-129 429.3 4.0 1.3e-128 428.7 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DNA_methylase PF00145.12 KFX91510.1 - 8e-47 159.9 0.0 6.3e-46 157.0 0.0 2.5 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KFX91510.1 - 3.8e-26 91.1 0.0 2.4e-13 49.8 0.0 3.2 3 0 0 3 3 3 2 BAH domain F-box-like PF12937.2 KFX91511.1 - 0.0015 18.1 0.5 0.0015 18.1 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFX91511.1 - 0.0021 17.6 0.2 0.0021 17.6 0.1 1.8 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KFX91511.1 - 0.0094 15.6 0.1 0.039 13.6 0.0 2.1 2 1 0 2 2 2 1 F-box-like domain Pkinase PF00069.20 KFX91516.1 - 0.0003 20.0 0.0 0.0003 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91516.1 - 0.0041 16.2 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX91516.1 - 0.011 14.8 0.1 0.013 14.5 0.1 1.2 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX91516.1 - 0.022 14.4 0.5 0.031 14.0 0.4 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1192 PF06698.6 KFX91516.1 - 0.086 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MIP PF00230.15 KFX91517.1 - 1.7e-45 155.2 10.9 2.2e-45 154.8 7.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF3262 PF11660.3 KFX91517.1 - 5.5 7.1 7.9 0.4 10.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) AAA_33 PF13671.1 KFX91518.1 - 1.7e-13 50.6 0.0 2.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX91518.1 - 8.3e-09 36.3 0.0 1.3e-08 35.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX91518.1 - 1.5e-08 35.0 0.0 4e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX91518.1 - 1e-07 31.2 0.0 2.3e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin SKI PF01202.17 KFX91518.1 - 0.0013 18.6 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.1 KFX91518.1 - 0.0035 17.3 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KFX91518.1 - 0.0045 16.6 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CoaE PF01121.15 KFX91518.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase KTI12 PF08433.5 KFX91518.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.24 KFX91518.1 - 0.026 14.7 0.0 0.06 13.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX91518.1 - 0.044 13.7 0.0 0.095 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin2 PF13189.1 KFX91518.1 - 0.052 13.4 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Viral_helicase1 PF01443.13 KFX91518.1 - 0.079 12.4 0.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ADK PF00406.17 KFX91518.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 1 1 2 2 2 0 Adenylate kinase TauD PF02668.11 KFX91519.1 - 9.3e-35 120.5 0.0 1.3e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KFX91520.1 - 2.6e-13 49.4 27.9 2.6e-13 49.4 19.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFX91520.1 - 2.2e-08 33.7 4.4 5.1e-08 32.5 3.1 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 KFX91520.1 - 0.00026 19.7 5.2 0.00026 19.7 3.6 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter CN_hydrolase PF00795.17 KFX91520.1 - 0.023 14.0 0.2 0.067 12.5 0.1 1.7 2 0 0 2 2 2 0 Carbon-nitrogen hydrolase Ribosomal_L2_C PF03947.13 KFX91523.1 - 4.5e-46 155.8 1.4 9.9e-46 154.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFX91523.1 - 6.3e-26 90.1 0.1 1.4e-25 89.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 KFX91524.1 - 4.4e-46 155.5 0.1 5.2e-44 148.8 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFX91524.1 - 3.1e-35 120.6 0.0 5.8e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PEMT PF04191.8 KFX91525.1 - 1.3e-32 112.0 3.2 2.5e-32 111.1 1.7 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.6 KFX91526.1 - 9.4e-40 135.8 0.2 9.4e-40 135.8 0.1 3.3 3 1 0 3 3 3 1 RXT2-like, N-terminal Gryzun PF07919.7 KFX91527.1 - 1e-99 334.4 0.0 1.3e-99 334.0 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KFX91527.1 - 4.5e-25 88.5 0.5 6.4e-25 88.0 0.3 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 KFX91527.1 - 0.002 17.8 0.3 0.005 16.6 0.0 1.8 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 KFX91528.1 - 1.7e-25 90.2 0.6 2.6e-25 89.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX91528.1 - 0.001 18.7 0.0 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioredoxin_2 PF13098.1 KFX91528.1 - 0.025 14.7 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain BRCT PF00533.21 KFX91529.1 - 2.1e-32 111.0 0.0 7e-09 35.7 0.0 6.4 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFX91529.1 - 2.2e-29 101.0 0.1 3.1e-18 65.3 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain ESCRT-II PF05871.7 KFX91530.1 - 6.7e-51 171.8 0.3 1.1e-50 171.2 0.2 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit NARP1 PF12569.3 KFX91531.1 - 1.1e-198 661.2 32.4 3.2e-198 659.7 15.8 2.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KFX91531.1 - 1e-20 73.1 38.5 3.5e-07 29.7 0.2 7.9 7 1 1 8 8 8 6 TPR repeat TPR_16 PF13432.1 KFX91531.1 - 1.6e-16 60.4 32.2 0.001 19.6 0.3 8.7 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX91531.1 - 1.2e-15 57.5 33.5 0.00042 20.6 0.3 7.2 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFX91531.1 - 6e-14 51.0 10.1 0.00023 21.1 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX91531.1 - 1.5e-12 46.9 30.1 0.0011 19.4 0.0 11.2 8 3 5 13 13 12 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX91531.1 - 1.1e-11 43.7 38.1 8.3e-05 22.2 0.1 10.8 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFX91531.1 - 1.5e-09 37.5 7.2 0.00029 20.6 0.2 5.9 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX91531.1 - 1.8e-09 36.7 31.1 1.9e-06 27.2 0.1 8.3 9 1 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 KFX91531.1 - 3e-08 33.6 21.2 0.015 15.3 0.6 5.8 4 3 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KFX91531.1 - 3.2e-07 29.6 19.9 0.00025 20.6 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX91531.1 - 5.9e-07 29.3 34.6 0.041 13.8 0.6 7.4 6 2 1 8 8 7 4 Tetratricopeptide repeat TPR_3 PF07720.7 KFX91531.1 - 0.015 15.0 4.5 0.033 13.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 KFX91531.1 - 0.035 14.7 6.1 2.1 9.1 0.3 4.1 3 0 0 3 3 3 0 Sel1 repeat TPR_6 PF13174.1 KFX91531.1 - 0.047 14.1 32.4 1.5 9.4 0.1 9.6 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX91531.1 - 0.081 12.7 19.6 1 9.3 0.0 6.7 6 1 1 7 7 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFX91531.1 - 0.11 12.3 13.1 7.3 6.5 0.1 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 KFX91531.1 - 0.15 12.5 11.4 5.8 7.6 0.7 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NAM-associated PF14303.1 KFX91531.1 - 0.21 11.8 8.5 0.37 11.0 0.0 3.0 3 0 0 3 3 2 0 No apical meristem-associated C-terminal domain Homoserine_dh PF00742.14 KFX91532.1 - 1.2e-52 178.1 0.0 1.7e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KFX91532.1 - 1.9e-18 66.9 0.0 3.1e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_4 PF02390.12 KFX91534.1 - 5.8e-53 178.8 0.0 7e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX91534.1 - 0.00014 22.4 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX91534.1 - 0.00024 21.4 0.2 0.00081 19.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX91534.1 - 0.0005 20.4 0.0 0.00098 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX91534.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX91534.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFX91534.1 - 0.0047 16.6 0.0 0.0099 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 KFX91534.1 - 0.0047 15.9 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 KFX91534.1 - 0.0076 16.7 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91534.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PXA PF02194.10 KFX91535.1 - 1.6e-48 164.7 0.4 1.6e-48 164.7 0.3 2.8 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KFX91535.1 - 2e-29 101.9 0.1 6.1e-29 100.3 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KFX91535.1 - 2e-20 72.6 0.6 6.2e-20 71.0 0.4 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KFX91535.1 - 2.8e-10 40.3 0.0 8.5e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2964 PF11177.3 KFX91535.1 - 0.044 13.7 2.4 0.098 12.6 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) RRM_1 PF00076.17 KFX91536.1 - 6.4e-12 44.9 0.2 1.8e-05 24.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX91536.1 - 7.6e-11 41.8 0.2 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91536.1 - 1.7e-06 27.7 0.0 4.8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ELL PF10390.4 KFX91536.1 - 0.071 12.3 0.9 0.14 11.3 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL Brevenin PF03032.10 KFX91542.1 - 0.17 11.7 5.5 0.26 11.1 3.8 1.3 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family RRM_1 PF00076.17 KFX91543.1 - 2e-38 129.8 0.1 1.2e-12 47.2 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX91543.1 - 6.1e-38 128.6 0.0 8.2e-09 35.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91543.1 - 1.8e-17 62.9 0.0 0.00027 20.7 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 KFX91543.1 - 1.4e-13 50.1 4.1 1.4e-13 50.1 2.8 3.1 3 0 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 KFX91543.1 - 7.2e-05 22.5 0.1 0.04 13.7 0.1 2.5 2 0 0 2 2 2 2 RNA binding motif AMP-binding PF00501.23 KFX91561.1 - 4.2e-31 107.7 0.1 5.8e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX91561.1 - 1.2e-09 38.9 0.1 6.1e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KFX91576.1 - 7.2e-10 38.6 11.7 1.3e-09 37.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX91576.1 - 3.2e-09 36.0 0.0 6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_30 PF13556.1 KFX91576.1 - 0.049 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Bac_rhamnosid PF05592.6 KFX91577.1 - 4.6e-170 566.1 0.0 5.7e-170 565.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KFX91577.1 - 8.7e-56 188.1 0.0 7.4e-55 185.0 0.0 2.3 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_1 PF00232.13 KFX91578.1 - 1e-132 442.6 0.0 1.2e-132 442.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sugar_tr PF00083.19 KFX91579.1 - 1.4e-65 221.6 29.1 1.6e-65 221.4 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91579.1 - 2.5e-13 49.4 36.9 2.3e-08 33.1 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MEDS PF14417.1 KFX91579.1 - 0.038 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF4538 PF15061.1 KFX91579.1 - 0.094 12.0 0.3 0.094 12.0 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Helicase_C_2 PF13307.1 KFX91584.1 - 2.9e-55 186.7 0.0 7.8e-55 185.3 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFX91584.1 - 4.3e-48 163.0 0.0 7.2e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KFX91584.1 - 0.0032 17.3 0.0 3.9 7.2 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFX91584.1 - 0.16 10.7 0.0 0.81 8.4 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain DUF641 PF04859.7 KFX91584.1 - 0.24 11.1 2.2 0.98 9.1 1.0 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Ribosomal_L18e PF00828.14 KFX91585.1 - 2.3e-34 118.5 0.1 3.2e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 KFX91586.1 - 6.9e-41 140.1 0.0 5.9e-37 127.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91586.1 - 5.8e-13 48.5 0.0 5.6e-07 28.8 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX91586.1 - 3.7e-05 22.8 0.0 0.039 12.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFX91586.1 - 0.004 16.9 0.0 0.088 12.5 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Cnd1_N PF12922.2 KFX91587.1 - 1.4e-58 197.3 0.3 1e-57 194.5 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KFX91587.1 - 2.1e-54 184.0 6.1 2.1e-50 171.0 1.4 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFX91587.1 - 2.1e-11 43.9 5.4 8.6e-06 25.9 0.0 5.7 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 KFX91587.1 - 2.4e-07 30.2 8.7 0.025 14.6 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KFX91587.1 - 3.2e-05 24.2 9.0 0.024 15.1 0.0 5.6 5 1 1 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 KFX91587.1 - 0.011 15.6 0.0 5.2 7.0 0.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 KFX91587.1 - 0.016 15.1 0.2 7.5 6.6 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion p450 PF00067.17 KFX91587.1 - 0.05 12.1 0.6 0.095 11.2 0.4 1.4 1 0 0 1 1 1 0 Cytochrome P450 MAM33 PF02330.11 KFX91588.1 - 7.1e-31 107.5 4.4 8.5e-31 107.3 3.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 KFX91589.1 - 7.6e-44 149.0 1.0 8.7e-44 148.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3847 PF12958.2 KFX91589.1 - 0.05 13.3 2.8 0.084 12.6 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) PAS_9 PF13426.1 KFX91589.1 - 0.15 12.4 0.2 0.62 10.4 0.0 1.9 1 1 1 2 2 2 0 PAS domain XPG_I PF00867.13 KFX91590.1 - 2.3e-26 91.6 0.1 5.6e-26 90.4 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFX91590.1 - 1.2e-20 73.6 0.0 2.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KFX91590.1 - 0.00042 19.8 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing IBR PF01485.16 KFX91591.1 - 8.1e-22 76.8 44.1 3.1e-11 42.9 3.5 4.4 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KFX91591.1 - 1.3e-05 25.1 7.8 1.3e-05 25.1 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX91591.1 - 0.00045 19.8 6.6 0.00045 19.8 4.6 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX91591.1 - 0.0017 18.1 7.6 0.0017 18.1 5.3 3.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 KFX91591.1 - 0.024 14.5 29.1 0.066 13.0 0.6 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING PIP5K PF01504.13 KFX91592.1 - 1.7e-83 279.6 0.1 1.7e-83 279.6 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.14 KFX91593.1 - 1.3e-23 82.8 1.4 2.7e-23 81.8 1.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_S21 PF00716.12 KFX91593.1 - 0.085 12.1 12.8 0.12 11.6 8.9 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Menin PF05053.8 KFX91593.1 - 1.6 6.8 10.7 1.7 6.6 7.4 1.1 1 0 0 1 1 1 0 Menin XPG_I PF00867.13 KFX91595.1 - 5.9e-31 106.3 0.6 2.4e-30 104.4 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KFX91595.1 - 2.6e-21 75.7 0.1 4.2e-20 71.8 0.0 2.6 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KFX91595.1 - 6.8e-06 26.2 0.2 6.6e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Acyl-CoA_dh_N PF02771.11 KFX91596.1 - 1.7e-22 80.1 0.7 2.8e-22 79.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KFX91596.1 - 2.4e-22 79.6 0.1 5.1e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX91596.1 - 2.8e-16 58.7 0.0 6.2e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX91596.1 - 2.8e-05 24.3 0.0 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 KFX91597.1 - 2.6e-49 166.2 0.0 3.3e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX91597.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KFX91597.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 KFX91597.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 KFX91598.1 - 3e-32 111.6 0.0 6.3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX91598.1 - 5e-20 71.3 0.0 1.4e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFX91598.1 - 2.5e-18 66.3 18.2 1.6e-17 63.7 8.8 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFX91598.1 - 0.0004 20.4 0.0 0.00092 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFX91598.1 - 0.072 13.6 0.0 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2272 PF10030.4 KFX91598.1 - 0.17 11.2 0.9 0.85 9.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) 2-Hacid_dh_C PF02826.14 KFX91599.1 - 1.9e-52 177.0 0.0 3.6e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX91599.1 - 4e-22 78.1 0.0 5.9e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX91599.1 - 7.3e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KFX91599.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 KFX91599.1 - 0.034 13.5 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KFX91599.1 - 0.049 13.6 0.2 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 KFX91599.1 - 0.055 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFX91599.1 - 0.096 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 KFX91599.1 - 0.11 12.8 0.8 1.9 8.9 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFX91599.1 - 0.12 11.9 0.1 0.94 9.0 0.0 2.2 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KFX91600.1 - 1.6e-32 112.5 32.6 2.2e-32 112.1 22.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 KFX91620.1 - 1.8e-09 37.2 1.3 2.6e-09 36.7 0.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX91620.1 - 8.3e-05 22.6 0.1 0.00014 21.9 0.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX91620.1 - 0.00011 22.2 1.2 0.00015 21.6 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX91620.1 - 0.0002 21.1 0.7 0.0003 20.5 0.5 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KFX91620.1 - 0.001 18.6 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX91620.1 - 0.054 13.1 0.4 0.086 12.5 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Coatomer_WDAD PF04053.9 KFX91621.1 - 0.76 8.5 0.0 1.2 7.7 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region DUF908 PF06012.7 KFX91622.1 - 0.13 11.4 1.0 0.21 10.8 0.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) UDPGP PF01704.13 KFX91623.1 - 3.8e-135 450.6 0.6 4.5e-135 450.3 0.4 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Neurensin PF14927.1 KFX91624.1 - 0.0002 20.7 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Neurensin DUF2721 PF11026.3 KFX91624.1 - 0.021 14.4 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Flavi_M PF01004.14 KFX91624.1 - 0.051 13.0 0.1 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M DUF912 PF06024.7 KFX91624.1 - 0.071 13.1 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2909 PF11137.3 KFX91624.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Herpes_US9 PF06072.6 KFX91624.1 - 0.1 12.4 1.1 0.2 11.5 0.8 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 adh_short PF00106.20 KFX91644.1 - 2.8e-12 46.8 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91644.1 - 2.2e-06 27.4 0.0 3.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX91644.1 - 0.00051 19.8 0.0 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 KFX91644.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KFX91644.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family O-FucT PF10250.4 KFX91644.1 - 0.057 12.5 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase NAD_binding_10 PF13460.1 KFX91644.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DEAD PF00270.24 KFX91646.1 - 1.1e-42 145.3 0.1 2.1e-42 144.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX91646.1 - 2e-20 72.4 0.0 1.1e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX91646.1 - 0.0008 19.2 0.0 0.0008 19.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFX91646.1 - 0.033 14.3 0.1 0.084 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 KFX91646.1 - 0.65 9.8 11.9 1.4 8.7 8.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FtsJ PF01728.14 KFX91647.1 - 4e-61 206.1 0.0 7.9e-61 205.2 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Acetyltransf_7 PF13508.1 KFX91648.1 - 2.8e-08 33.8 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX91648.1 - 1.8e-07 31.1 0.0 2.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX91648.1 - 0.00015 21.9 0.0 0.00024 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX91648.1 - 0.00067 19.3 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFX91648.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M16_C PF05193.16 KFX91656.1 - 1.3e-49 168.3 0.0 6.6e-49 166.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFX91656.1 - 3e-43 147.1 0.0 5.5e-42 143.0 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) FHA PF00498.21 KFX91657.1 - 2.6e-14 53.0 0.0 4.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KFX91657.1 - 1.6e-05 24.6 10.3 2.5e-05 23.9 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX91657.1 - 0.0028 17.2 8.0 0.0046 16.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX91657.1 - 0.031 14.3 5.8 0.055 13.5 4.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 KFX91657.1 - 0.12 12.0 6.1 0.21 11.2 4.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 KFX91657.1 - 0.17 11.6 6.8 0.29 10.8 4.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 KFX91657.1 - 0.39 10.7 7.0 0.67 10.0 4.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 KFX91657.1 - 0.73 9.9 10.8 1.3 9.1 7.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 KFX91657.1 - 1.2 8.9 5.3 19 4.9 0.9 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain MARVEL PF01284.18 KFX91658.1 - 0.00019 21.2 8.2 0.00029 20.6 5.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF2665 PF11654.3 KFX91658.1 - 0.074 12.6 2.0 4.6 6.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DUF4027 PF13219.1 KFX91658.1 - 4.8 6.6 5.6 0.72 9.3 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) Vps16_N PF04841.8 KFX91659.1 - 3.8e-99 332.0 0.0 5.1e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KFX91659.1 - 2.6e-80 269.7 0.0 4e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Coatomer_WDAD PF04053.9 KFX91659.1 - 0.023 13.4 0.0 4.6 5.9 0.0 3.1 3 0 0 3 3 3 0 Coatomer WD associated region HD PF01966.17 KFX91665.1 - 0.00036 20.5 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 HD domain Aa_trans PF01490.13 KFX91666.1 - 3.5e-29 101.5 37.5 4.5e-29 101.1 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MBOAT PF03062.14 KFX91669.1 - 2.4e-32 112.3 19.4 1.2e-31 110.0 13.4 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Adaptin_N PF01602.15 KFX91670.1 - 6.2e-141 470.2 0.1 7.5e-141 470.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KFX91670.1 - 9.1e-14 51.7 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KFX91670.1 - 3.2e-05 24.1 5.2 0.067 13.4 0.0 4.6 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KFX91670.1 - 0.00058 20.2 1.0 13 6.4 0.0 5.2 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 KFX91670.1 - 0.0008 19.3 1.5 0.052 13.4 0.1 3.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 KFX91670.1 - 0.021 14.4 0.3 0.072 12.6 0.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) HEAT PF02985.17 KFX91670.1 - 0.71 10.1 8.6 16 5.9 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat AAA_17 PF13207.1 KFX91671.1 - 3.7e-16 60.0 0.0 4.3e-16 59.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX91671.1 - 7.4e-07 29.5 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFX91671.1 - 2.3e-05 24.4 0.0 3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX91671.1 - 0.00027 20.8 0.0 0.00052 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX91671.1 - 0.00064 19.9 0.0 0.00089 19.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 KFX91671.1 - 0.001 18.9 0.2 0.0039 17.0 0.1 1.9 1 1 1 2 2 2 1 Shikimate kinase AAA_24 PF13479.1 KFX91671.1 - 0.0017 17.9 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFX91671.1 - 0.0024 16.7 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 KFX91671.1 - 0.0025 16.8 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KFX91671.1 - 0.0048 17.1 0.0 0.0065 16.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 KFX91671.1 - 0.0054 15.8 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KFX91671.1 - 0.0088 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KFX91671.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 KFX91671.1 - 0.015 14.7 0.3 0.024 14.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KFX91671.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KFX91671.1 - 0.023 14.3 0.4 0.044 13.4 0.3 1.7 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KFX91671.1 - 0.053 13.5 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KFX91671.1 - 0.075 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KFX91671.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 KFX91671.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin2 PF13189.1 KFX91671.1 - 0.11 12.3 0.1 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family RuvB_N PF05496.7 KFX91671.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus cobW PF02492.14 KFX91671.1 - 0.13 11.6 0.2 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KFX91671.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 NTPase KaiC PF06745.8 KFX91671.1 - 0.14 11.2 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 KaiC Metallophos PF00149.23 KFX91686.1 - 2.6e-17 62.8 0.0 4.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX91686.1 - 2.4e-05 24.2 0.0 5.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NUDIX PF00293.23 KFX91687.1 - 9.7e-16 57.6 0.6 1.1e-15 57.4 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 KFX91687.1 - 0.0022 17.3 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase Mononeg_mRNAcap PF14318.1 KFX91694.1 - 0.097 11.6 0.5 0.16 10.9 0.3 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V APH PF01636.18 KFX91695.1 - 1.9e-07 31.1 0.0 4.1e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX91695.1 - 4.5e-05 23.1 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFX91695.1 - 0.01 15.0 0.0 3.2 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain adh_short PF00106.20 KFX91696.1 - 5.9e-21 75.1 0.1 8.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91696.1 - 1.3e-08 34.6 0.2 2.8e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFX91696.1 - 0.00012 21.5 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX91696.1 - 0.0008 18.1 0.2 0.0016 17.2 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.13 KFX91697.1 - 6.4e-07 29.1 14.4 6.4e-07 29.1 10.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DBP PF12361.3 KFX91697.1 - 0.049 13.1 4.3 0.096 12.1 2.8 1.4 1 1 0 1 1 1 0 Duffy-antigen binding protein VPS28 PF03997.7 KFX91697.1 - 0.3 10.6 1.4 0.57 9.7 1.0 1.3 1 0 0 1 1 1 0 VPS28 protein zf-C2H2 PF00096.21 KFX91697.1 - 6.8 7.2 11.2 0.15 12.4 2.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type IDO PF01231.13 KFX91698.1 - 6.1e-16 57.8 0.0 6.8e-13 47.8 0.0 2.3 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.23 KFX91698.1 - 7.9e-13 48.0 0.0 2.9e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.15 KFX91698.1 - 2.3e-12 46.8 0.0 4.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFX91698.1 - 2.9e-09 37.4 0.0 6.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Lipase_GDSL_2 PF13472.1 KFX91699.1 - 1.9e-09 37.9 0.7 2.5e-09 37.5 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX91699.1 - 2.1e-09 37.5 3.7 1.5e-08 34.7 2.6 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Saccharop_dh PF03435.13 KFX91700.1 - 3e-18 65.9 0.2 4.6e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KFX91701.1 - 2.4e-11 43.5 0.0 3.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX91701.1 - 3.5e-11 43.4 0.7 1.4e-10 41.4 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX91701.1 - 3.7e-05 23.1 0.1 5.4e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFX91701.1 - 3.8e-05 22.5 0.1 5.3e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 KFX91701.1 - 0.0026 17.1 0.1 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 KFX91701.1 - 0.058 12.2 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-U11-48K PF05253.7 KFX91702.1 - 0.042 13.5 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger DUF2873 PF11395.3 KFX91702.1 - 0.12 11.9 2.2 0.58 9.7 1.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Adeno_E3_CR2 PF02439.10 KFX91702.1 - 1.5 8.3 5.5 0.36 10.3 0.8 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 PMP1_2 PF08114.6 KFX91702.1 - 4.6 6.8 7.7 0.73 9.3 0.6 2.8 2 0 0 2 2 2 0 ATPase proteolipid family MFS_1 PF07690.11 KFX91703.1 - 7.1e-17 61.1 43.9 7.1e-17 61.1 30.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0093 PF03653.8 KFX91703.1 - 0.071 13.0 4.7 0.11 12.4 1.9 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) Aldedh PF00171.17 KFX91704.1 - 1.1e-116 389.9 0.3 1.6e-116 389.4 0.2 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_3 PF03447.11 KFX91704.1 - 0.024 15.0 0.1 0.056 13.8 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Zn_clus PF00172.13 KFX91705.1 - 5.7e-08 32.5 9.2 1.1e-07 31.5 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX91705.1 - 1.5e-07 30.3 2.3 3.3e-07 29.2 1.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX91710.1 - 1.9e-21 76.1 51.6 2.2e-18 66.0 25.9 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily PPR_2 PF13041.1 KFX91711.1 - 1.5e-09 37.7 0.8 2.4 8.1 0.0 6.7 5 1 2 7 7 7 4 PPR repeat family PPR_3 PF13812.1 KFX91711.1 - 2.3e-09 36.7 1.0 0.033 14.4 0.0 6.8 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 KFX91711.1 - 0.00075 19.3 10.8 1 9.4 0.0 6.6 9 0 0 9 9 9 2 PPR repeat DUF1244 PF06844.6 KFX91712.1 - 0.011 15.6 1.2 0.025 14.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) DnaJ_CXXCXGXG PF00684.14 KFX91712.1 - 0.51 10.4 12.7 3.4 7.7 8.8 2.0 1 1 0 1 1 1 0 DnaJ central domain SLBB PF10531.4 KFX91714.1 - 0.017 14.9 0.1 2.4 8.0 0.0 2.3 1 1 1 2 2 2 0 SLBB domain Fungal_trans_2 PF11951.3 KFX91717.1 - 2.7e-18 65.7 5.7 9.6e-14 50.7 2.2 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain Desmo_N PF06771.6 KFX91719.1 - 0.042 13.7 0.8 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus Peptidase_C48 PF02902.14 KFX91720.1 - 1.2e-05 25.0 0.0 2.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.24 KFX91720.1 - 0.25 11.0 4.8 0.53 10.0 3.3 1.5 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.14 KFX91720.1 - 0.72 9.7 9.8 0.16 11.7 3.4 2.7 2 0 0 2 2 2 0 AT hook motif FAD_binding_3 PF01494.14 KFX91722.1 - 6.1e-19 68.2 0.0 7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX91722.1 - 1.4e-14 53.8 1.0 1.8e-07 30.3 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX91722.1 - 4e-08 33.1 0.1 8.7e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX91722.1 - 2.7e-07 29.4 0.0 2.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KFX91722.1 - 2.1e-06 26.8 0.0 3.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFX91722.1 - 1.5e-05 25.3 0.0 0.00022 21.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX91722.1 - 1.6e-05 24.8 0.0 2.1e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX91722.1 - 3.6e-05 22.5 0.0 0.055 12.0 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 KFX91722.1 - 6e-05 22.1 0.1 0.0039 16.1 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 KFX91722.1 - 9.6e-05 21.6 0.0 0.0033 16.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KFX91722.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFX91722.1 - 0.00038 20.0 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KFX91722.1 - 0.00053 19.1 0.0 0.0016 17.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 KFX91722.1 - 0.00069 18.8 0.7 0.0019 17.3 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KFX91722.1 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_10 PF13460.1 KFX91722.1 - 0.0034 17.3 0.1 0.0057 16.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 KFX91722.1 - 0.019 14.4 0.1 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX91722.1 - 0.019 14.6 0.1 0.088 12.4 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KFX91722.1 - 0.031 14.0 0.2 0.12 12.1 0.1 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Rossmann-like PF10727.4 KFX91722.1 - 0.034 13.8 0.3 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain TrkA_N PF02254.13 KFX91722.1 - 0.036 14.0 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 KFX91722.1 - 0.059 13.6 0.0 0.094 12.9 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KFX91722.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KFX91722.1 - 0.092 12.8 0.1 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KFX91722.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UBA PF00627.26 KFX91730.1 - 5e-10 38.9 0.3 7.1e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 UBA/TS-N domain NACHT PF05729.7 KFX91731.1 - 7e-10 38.8 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFX91731.1 - 2.1e-07 31.0 0.0 9.7e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFX91731.1 - 0.00075 19.6 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFX91731.1 - 0.0034 17.5 0.0 0.0075 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 KFX91731.1 - 0.015 15.0 0.1 0.97 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KFX91731.1 - 0.034 14.3 0.0 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFX91731.1 - 0.052 14.3 0.2 1.4 9.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.1 KFX91731.1 - 0.055 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KFX91731.1 - 0.067 12.6 0.1 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein PS_Dcarbxylase PF02666.10 KFX91731.1 - 0.11 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase GMC_oxred_N PF00732.14 KFX91732.1 - 3e-50 171.0 0.0 3.9e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX91732.1 - 2.5e-34 118.6 0.0 4.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX91732.1 - 2.6e-06 26.5 0.9 0.063 12.1 0.9 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFX91732.1 - 0.0013 17.7 0.0 0.0028 16.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KFX91732.1 - 0.0042 16.0 0.0 0.009 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX91732.1 - 0.014 15.2 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX91732.1 - 0.023 13.7 0.1 0.056 12.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 KFX91732.1 - 0.03 14.3 0.4 0.084 12.9 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX91732.1 - 0.15 12.1 0.0 4 7.4 0.0 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.14 KFX91733.1 - 8.3e-161 534.9 2.3 1e-160 534.6 1.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFX91733.1 - 3.3e-14 52.4 0.0 7.2e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Methyltransf_PK PF05891.7 KFX91733.1 - 0.11 11.8 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Pex14_N PF04695.8 KFX91734.1 - 0.041 13.9 0.4 0.047 13.7 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NeA_P2 PF12312.3 KFX91734.1 - 0.1 11.8 0.1 0.11 11.7 0.1 1.0 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein SBP_bac_5 PF00496.17 KFX91734.1 - 0.15 10.8 0.8 0.16 10.7 0.5 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle PAT1 PF09770.4 KFX91734.1 - 0.45 8.6 4.9 0.42 8.7 3.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4106 PF13388.1 KFX91734.1 - 5 5.9 7.5 5.3 5.8 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) EphA2_TM PF14575.1 KFX91735.1 - 0.0028 18.0 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1517 PF07466.6 KFX91735.1 - 0.068 12.1 1.3 0.11 11.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SKG6 PF08693.5 KFX91735.1 - 0.11 11.8 0.7 0.24 10.7 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_11 PF00457.12 KFX91736.1 - 1.1e-53 181.2 12.8 1.3e-53 181.0 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Na_H_Exchanger PF00999.16 KFX91738.1 - 2.5e-68 230.3 37.1 3.2e-68 229.9 25.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MFS_2 PF13347.1 KFX91739.1 - 0.0049 15.3 19.3 0.08 11.3 13.4 2.4 1 1 0 1 1 1 1 MFS/sugar transport protein PKD PF00801.15 KFX91740.1 - 0.18 11.5 8.5 3.7 7.3 1.3 2.7 1 1 1 2 2 2 0 PKD domain Aldedh PF00171.17 KFX91741.1 - 2.4e-178 593.2 0.5 3.2e-178 592.8 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_PK PF05891.7 KFX91741.1 - 2.5e-73 246.0 0.0 4.2e-73 245.2 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase bZIP_1 PF00170.16 KFX91742.1 - 0.3 11.0 7.8 0.89 9.5 5.4 1.8 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 KFX91742.1 - 10 6.0 24.6 0.057 13.2 7.8 3.2 2 1 1 3 3 3 0 Basic region leucine zipper FA_desaturase PF00487.19 KFX91745.1 - 5.8e-19 68.5 12.4 5.8e-19 68.5 8.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFX91745.1 - 1.8e-16 59.7 0.1 5.7e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pex14_N PF04695.8 KFX91745.1 - 0.19 11.7 0.6 1.5 8.8 0.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MOSC PF03473.12 KFX91746.1 - 3.7e-20 71.7 0.0 6.7e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KFX91746.1 - 2e-12 46.8 0.0 3.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain 4HBT PF03061.17 KFX91747.1 - 2.9e-13 49.7 0.0 4.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KFX91747.1 - 1.3e-06 28.3 0.1 2e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily SMC_N PF02463.14 KFX91748.1 - 1.1e-66 224.2 14.7 5.1e-66 222.0 10.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX91748.1 - 1.8e-22 79.5 0.9 1.1e-21 76.9 0.2 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFX91748.1 - 3.4e-12 46.9 9.0 3.2e-06 27.3 0.0 3.7 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 KFX91748.1 - 4.1e-12 46.8 15.7 4.1e-12 46.8 10.9 6.5 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 KFX91748.1 - 7.8e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFX91748.1 - 0.0021 17.3 33.3 0.23 10.6 1.1 6.3 3 2 2 6 6 6 4 Reovirus sigma C capsid protein ABC_tran PF00005.22 KFX91748.1 - 0.13 12.5 0.0 0.13 12.5 0.0 6.2 4 2 0 4 4 4 0 ABC transporter Fungal_trans_2 PF11951.3 KFX91748.1 - 4.6 5.7 11.1 0.37 9.3 0.3 3.3 3 0 0 3 3 3 0 Fungal specific transcription factor domain NDT80_PhoG PF05224.7 KFX91751.1 - 2.9e-42 144.7 0.0 5.6e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pyr_redox_2 PF07992.9 KFX91752.1 - 6.7e-12 45.7 6.5 1.3e-10 41.5 4.5 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX91752.1 - 8.9e-10 38.8 1.1 6.8e-09 36.0 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX91752.1 - 1.2e-05 25.5 1.2 0.00048 20.2 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX91752.1 - 0.00012 21.0 11.7 0.016 14.0 0.3 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFX91752.1 - 0.0051 15.7 0.4 0.01 14.7 0.1 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KFX91752.1 - 0.0092 14.4 2.2 4 5.7 0.1 3.4 4 0 0 4 4 4 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KFX91752.1 - 0.054 12.8 1.0 0.099 12.0 0.3 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 KFX91752.1 - 0.085 11.4 4.1 0.67 8.5 0.1 2.2 1 1 1 2 2 2 0 Tryptophan halogenase Chitin_bind_4 PF00379.18 KFX91752.1 - 0.1 12.8 1.9 2 8.7 0.2 2.8 2 0 0 2 2 2 0 Insect cuticle protein NAD_binding_7 PF13241.1 KFX91752.1 - 0.13 12.5 0.8 0.59 10.4 0.4 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 KFX91752.1 - 0.24 10.2 0.0 0.24 10.2 0.0 2.5 2 1 1 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KFX91752.1 - 0.64 9.7 8.4 5.8 6.6 0.1 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding RTA1 PF04479.8 KFX91753.1 - 4.2e-20 72.1 5.3 8.2e-20 71.2 3.7 1.4 1 1 0 1 1 1 1 RTA1 like protein Peptidase_C34 PF05413.6 KFX91753.1 - 0.11 12.6 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase MerC PF03203.9 KFX91753.1 - 2.2 8.6 11.1 0.27 11.6 0.2 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein RNase_H PF00075.19 KFX91754.1 - 5.7e-14 52.5 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Zn_clus PF00172.13 KFX91754.1 - 2e-07 30.7 13.0 3.9e-07 29.8 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_3 PF13456.1 KFX91754.1 - 0.0067 16.1 0.0 0.12 12.1 0.0 2.8 3 0 0 3 3 3 1 Reverse transcriptase-like DUF3666 PF12408.3 KFX91754.1 - 0.052 12.6 2.3 0.11 11.6 0.1 2.7 4 0 0 4 4 4 0 Ribose-5-phosphate isomerase EzrA PF06160.7 KFX91754.1 - 0.093 10.8 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-C2H2_6 PF13912.1 KFX91755.1 - 0.065 13.1 2.5 0.4 10.6 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFX91755.1 - 0.3 11.2 2.9 2 8.5 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFX91755.1 - 0.31 11.4 8.1 6.3 7.3 0.2 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 KFX91755.1 - 0.32 11.2 2.9 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX91755.1 - 0.41 10.8 3.5 0.49 10.6 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LIM PF00412.17 KFX91755.1 - 1 9.4 3.6 7.5 6.7 0.5 2.3 2 0 0 2 2 2 0 LIM domain BRO1 PF03097.13 KFX91757.1 - 3.4e-133 444.0 2.0 3.4e-133 444.0 1.4 2.5 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KFX91757.1 - 1.6e-91 306.3 11.9 1.6e-91 306.3 8.2 2.5 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Lon_C PF05362.8 KFX91757.1 - 1.3e-61 207.5 0.0 3e-61 206.3 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KFX91757.1 - 1.8e-36 125.7 0.1 1.8e-36 125.7 0.0 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KFX91757.1 - 3.7e-22 78.9 0.0 1.2e-21 77.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX91757.1 - 1.3e-06 28.1 0.0 3.6e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KFX91757.1 - 1.8e-05 24.2 0.0 4.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 KFX91757.1 - 3e-05 24.1 0.1 0.00055 20.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KFX91757.1 - 7.2e-05 21.6 0.0 0.00014 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KFX91757.1 - 9.6e-05 23.1 0.1 0.00076 20.2 0.0 2.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KFX91757.1 - 0.00046 19.3 0.0 0.0026 16.8 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX91757.1 - 0.0005 20.1 3.4 0.0019 18.2 0.0 3.5 4 0 0 4 4 3 1 AAA ATPase domain AAA_14 PF13173.1 KFX91757.1 - 0.0082 16.0 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX91757.1 - 0.022 15.0 3.6 0.059 13.6 0.0 3.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KFX91757.1 - 0.089 12.9 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase GRP PF07172.6 KFX91757.1 - 0.48 10.9 6.8 1.7 9.1 4.7 1.9 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.20 KFX91758.1 - 1.1e-11 44.4 0.0 4.1e-10 39.2 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91758.1 - 3.8e-10 39.2 0.0 3e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PALP PF00291.20 KFX91765.1 - 5e-25 88.3 0.4 5.8e-25 88.1 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 KFX91765.1 - 0.068 12.6 0.7 0.096 12.1 0.5 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF572 PF04502.8 KFX91766.1 - 1.8e-35 122.7 0.0 2.1e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-C2H2_2 PF12756.2 KFX91767.1 - 0.093 12.8 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PHD PF00628.24 KFX91772.1 - 3.4e-06 26.6 11.7 3.4e-06 26.6 8.1 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 KFX91772.1 - 0.044 13.7 7.0 0.14 12.1 4.9 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain PXA PF02194.10 KFX91775.1 - 0.021 14.3 0.2 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 PXA domain DLH PF01738.13 KFX91783.1 - 1.1e-15 57.5 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX91783.1 - 1.4e-06 28.0 0.0 1.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KFX91783.1 - 0.14 11.8 0.0 0.83 9.3 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans_2 PF11951.3 KFX91784.1 - 2.8e-15 55.8 1.0 4.4e-15 55.1 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91784.1 - 6.8e-07 29.0 11.6 1.2e-06 28.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pterin_bind PF00809.17 KFX91798.1 - 1.3e-61 207.6 0.0 2.1e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KFX91798.1 - 7.5e-40 135.5 0.0 1.4e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Mit_KHE1 PF10173.4 KFX91800.1 - 5.5e-62 208.9 0.8 6.6e-62 208.6 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SNF2_N PF00176.18 KFX91801.1 - 3.7e-69 232.8 0.6 7.2e-69 231.8 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX91801.1 - 6.2e-17 61.2 0.0 1.7e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX91801.1 - 1.3e-05 25.1 0.0 1.3e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFX91801.1 - 0.042 13.9 0.0 0.16 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 KFX91802.1 - 3.8e-07 30.2 1.5 1.2e-06 28.5 0.5 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX91802.1 - 0.00096 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M14 PF00246.19 KFX91803.1 - 0.061 12.9 0.1 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase AMP-binding PF00501.23 KFX91804.1 - 1.2e-74 251.2 0.0 3.1e-74 249.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFX91804.1 - 9.1e-71 237.6 0.0 1.3e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFX91804.1 - 3.9e-13 49.3 0.0 7.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KFX91804.1 - 1.6e-09 37.8 0.0 3.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KFX91804.1 - 1.6e-08 33.5 0.1 4.3e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KFX91804.1 - 3.9e-06 27.7 0.0 2.3e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KFX91804.1 - 0.0079 16.1 0.5 0.027 14.3 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX91804.1 - 0.033 13.1 0.0 0.079 11.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX91804.1 - 0.086 11.7 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Cupin_8 PF13621.1 KFX91808.1 - 6.3e-34 117.5 0.0 9.1e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFX91808.1 - 3.9e-08 32.9 0.0 7.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Ribul_P_3_epim PF00834.14 KFX91808.1 - 0.0017 17.5 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family JmjC PF02373.17 KFX91808.1 - 0.0068 16.6 0.0 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KFX91808.1 - 0.068 12.6 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Cupin domain DUF566 PF04484.7 KFX91809.1 - 3.6 7.0 6.3 3.6 6.9 4.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) FAD_binding_4 PF01565.18 KFX91810.1 - 2.4e-23 82.1 3.3 4.3e-23 81.3 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX91810.1 - 0.00037 20.3 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Adap_comp_sub PF00928.16 KFX91818.1 - 1.4e-73 247.2 0.0 1.9e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFX91818.1 - 1.7e-09 37.5 0.3 3e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Opi1 PF08618.5 KFX91819.1 - 1.9e-81 274.1 16.3 1.2e-50 172.7 3.5 3.9 2 1 2 4 4 4 3 Transcription factor Opi1 Exc PF07825.6 KFX91819.1 - 0.0034 17.0 0.6 0.032 13.9 0.0 2.5 2 0 0 2 2 2 1 Excisionase-like protein Myb_DNA-bind_6 PF13921.1 KFX91823.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFX91823.1 - 0.0038 17.3 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUP PF00674.13 KFX91823.1 - 0.017 15.0 0.3 0.047 13.6 0.2 1.7 1 1 0 1 1 1 0 DUP family Cluap1 PF10234.4 KFX91829.1 - 0.17 11.0 7.7 0.027 13.6 2.9 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 Methyltransf_23 PF13489.1 KFX91830.1 - 9e-21 74.2 0.0 1.6e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PLDc_2 PF13091.1 KFX91830.1 - 5.2e-14 52.0 0.0 2.1e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain Methyltransf_11 PF08241.7 KFX91830.1 - 1.5e-10 41.4 0.0 5.1e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91830.1 - 9e-09 35.0 0.0 1.2e-07 31.4 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX91830.1 - 5.9e-08 33.2 0.0 5.7e-07 30.1 0.0 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX91830.1 - 1.3e-07 31.9 0.0 5.4e-07 30.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX91830.1 - 1.6e-06 28.3 0.0 6.9e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX91830.1 - 5.1e-06 25.7 0.0 3.8e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PLDc PF00614.17 KFX91830.1 - 0.0035 17.1 0.1 0.91 9.4 0.0 2.8 2 0 0 2 2 2 1 Phospholipase D Active site motif PrmA PF06325.8 KFX91830.1 - 0.01 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KFX91830.1 - 0.013 15.0 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KFX91830.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 KFX91830.1 - 0.03 13.8 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Ribosomal_60s PF00428.14 KFX91830.1 - 0.08 13.3 0.8 0.23 11.8 0.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein MTS PF05175.9 KFX91830.1 - 0.18 11.1 0.0 0.53 9.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain RTA1 PF04479.8 KFX91831.1 - 1.4e-49 168.6 2.7 1.9e-49 168.1 1.9 1.1 1 0 0 1 1 1 1 RTA1 like protein ATP1G1_PLM_MAT8 PF02038.11 KFX91831.1 - 0.0061 15.5 0.1 0.0061 15.5 0.0 2.5 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family DUF2127 PF09900.4 KFX91831.1 - 2.4 8.1 8.0 0.38 10.7 0.6 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2127) Sugar_tr PF00083.19 KFX91832.1 - 1.8e-99 333.3 24.0 2.2e-99 333.0 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91832.1 - 3.1e-26 91.9 38.6 1e-18 67.1 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.15 KFX91832.1 - 0.00026 21.2 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFX91832.1 - 0.00031 21.2 0.0 0.00072 20.0 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Tmemb_18A PF09771.4 KFX91832.1 - 0.14 12.1 0.2 0.6 10.0 0.2 2.1 1 0 0 1 1 1 0 Transmembrane protein 188 MatC_N PF07158.6 KFX91832.1 - 0.88 9.3 10.1 0.65 9.8 4.2 2.7 3 0 0 3 3 3 0 Dicarboxylate carrier protein MatC N-terminus Lig_chan PF00060.21 KFX91832.1 - 2.2 7.9 8.4 2.9 7.6 0.2 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel Acyl_transf_3 PF01757.17 KFX91833.1 - 1.8e-16 59.9 17.9 2.5e-16 59.4 12.4 1.2 1 0 0 1 1 1 1 Acyltransferase family Alpha-L-AF_C PF06964.7 KFX91834.1 - 5.8e-34 117.3 0.2 8.1e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Fungal_trans_2 PF11951.3 KFX91835.1 - 3.4e-58 197.1 1.8 4.3e-58 196.7 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91835.1 - 1.6e-05 24.7 7.7 3.4e-05 23.6 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 KFX91836.1 - 5.4e-99 331.6 36.5 6.6e-99 331.4 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX91836.1 - 2.8e-21 75.5 37.6 4.4e-21 74.9 26.1 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 KFX91836.1 - 3.9 6.8 7.4 1.2 8.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF1772 PF08592.6 KFX91836.1 - 9 6.0 12.3 3.3 7.4 2.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) PEX11 PF05648.9 KFX91837.1 - 1.3e-27 96.5 0.0 1.5e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M20 PF01546.23 KFX91838.1 - 1.7e-24 86.4 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX91838.1 - 1.6e-10 40.7 0.0 2.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFX91838.1 - 0.04 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M24 PF00557.19 KFX91839.1 - 1.9e-20 73.3 0.1 2.8e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFX91839.1 - 1.9e-15 57.5 0.0 3.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Snurportin1 PF11538.3 KFX91839.1 - 0.11 12.2 0.6 0.3 10.8 0.4 1.7 1 0 0 1 1 1 0 Snurportin1 Beta_elim_lyase PF01212.16 KFX91840.1 - 5.5e-77 258.7 0.0 1e-76 257.8 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFX91840.1 - 6.9e-05 21.3 0.0 9.2e-05 20.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFX91840.1 - 0.0013 17.7 0.0 0.0046 15.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aldedh PF00171.17 KFX91841.1 - 2.1e-185 616.4 0.2 2.4e-185 616.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_32C PF08244.7 KFX91842.1 - 5.9e-19 68.2 0.5 1.1e-18 67.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KFX91842.1 - 8e-18 64.8 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_11 PF08241.7 KFX91843.1 - 5e-06 26.9 0.0 9.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HpcH_HpaI PF03328.9 KFX91844.1 - 9.2e-26 90.0 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SET PF00856.23 KFX91852.1 - 5.9e-12 46.1 0.0 1.2e-10 41.9 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF1221 PF06760.6 KFX91852.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) MmgE_PrpD PF03972.9 KFX91854.1 - 3e-149 497.0 0.0 3.6e-149 496.7 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family DUF1435 PF07256.7 KFX91856.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Toxin_23 PF08093.6 KFX91856.1 - 3.1 7.7 10.6 0.2 11.6 3.5 1.9 2 0 0 2 2 2 0 Magi 5 toxic peptide family FA_hydroxylase PF04116.8 KFX91861.1 - 4.1e-12 46.5 2.4 4.1e-12 46.5 1.6 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Stn1 PF10451.4 KFX91861.1 - 0.04 12.7 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Retrotrans_gag PF03732.12 KFX91862.1 - 1.3e-05 25.1 0.1 3.7e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein DUF1759 PF03564.10 KFX91862.1 - 8.7e-05 22.3 0.2 0.00012 21.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) SPOUT_MTase PF02590.12 KFX91862.1 - 0.0056 16.3 0.1 0.0078 15.9 0.1 1.1 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase DUF336 PF03928.9 KFX91863.1 - 2.9e-35 120.9 0.2 3.4e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Diacid_rec PF05651.8 KFX91863.1 - 0.23 10.8 1.0 0.31 10.4 0.2 1.6 2 0 0 2 2 2 0 Putative sugar diacid recognition ADH_N PF08240.7 KFX91864.1 - 5e-27 93.8 0.7 5e-27 93.8 0.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX91864.1 - 2.8e-07 30.1 0.0 0.00027 20.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFX91864.1 - 0.014 15.0 0.0 0.014 15.0 0.0 2.3 3 0 0 3 3 3 0 Alcohol dehydrogenase GroES-associated FANCL_C PF11793.3 KFX91864.1 - 0.029 14.3 0.5 0.064 13.2 0.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain UDPGT PF00201.13 KFX91865.1 - 2.5e-08 32.9 0.0 3.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase adh_short_C2 PF13561.1 KFX91870.1 - 6.4e-30 104.6 0.6 2.1e-29 102.9 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX91870.1 - 1.3e-25 90.2 7.7 3.9e-22 78.9 1.8 2.7 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 KFX91870.1 - 6e-13 48.7 0.2 3.3e-11 43.0 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFX91870.1 - 5.7e-10 39.1 3.9 5.8e-09 35.8 0.5 2.7 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 KFX91870.1 - 1.6e-09 36.8 0.0 3.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX91870.1 - 6.7e-09 35.9 0.6 8.8e-08 32.3 0.1 2.6 2 1 0 2 2 2 1 NADH(P)-binding SUR7 PF06687.7 KFX91870.1 - 1.5e-07 31.2 0.8 2.6e-07 30.4 0.5 1.3 1 0 0 1 1 1 1 SUR7/PalI family NAD_binding_4 PF07993.7 KFX91870.1 - 3.2e-06 26.2 0.6 0.0019 17.2 0.1 2.8 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KFX91870.1 - 0.00065 18.6 0.6 0.0018 17.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KFX91870.1 - 0.013 15.2 0.2 0.092 12.5 0.1 2.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KFX91870.1 - 0.05 12.8 0.9 0.094 11.9 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family DUF1067 PF06362.6 KFX91871.1 - 0.018 15.6 0.1 0.023 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) Epimerase PF01370.16 KFX91872.1 - 3.3e-08 33.2 0.0 1.3e-07 31.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX91872.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 KFX91873.1 - 5.1e-14 51.6 0.3 7.1e-14 51.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.16 KFX91879.1 - 1.6e-80 270.8 0.0 2e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFX91879.1 - 4.9e-06 25.5 0.1 5.1e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFX91879.1 - 0.001 17.4 0.0 0.0017 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KFX91879.1 - 0.012 14.7 0.6 0.025 13.7 0.4 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Choline_transpo PF04515.7 KFX91881.1 - 7e-101 337.2 31.0 7e-101 337.2 21.5 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Cellulase PF00150.13 KFX91882.1 - 2.1e-17 63.2 0.0 2.6e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SWIRM PF04433.12 KFX91888.1 - 1.6e-12 47.3 0.0 2e-11 43.8 0.0 2.6 2 1 0 2 2 2 1 SWIRM domain DUF566 PF04484.7 KFX91888.1 - 0.19 11.2 5.2 0.22 10.9 3.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Sugar_tr PF00083.19 KFX91890.1 - 1.2e-116 390.0 24.8 2e-116 389.2 17.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91890.1 - 1.9e-31 109.0 53.8 8e-25 87.2 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 KFX91890.1 - 0.0015 18.2 0.4 0.0071 15.9 0.3 2.2 1 0 0 1 1 1 1 Lysis protein S peroxidase PF00141.18 KFX91891.1 - 3.8e-87 291.5 0.0 1.6e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Herpes_U59 PF04529.7 KFX91891.1 - 0.096 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus U59 protein CN_hydrolase PF00795.17 KFX91892.1 - 8e-26 90.5 0.0 1.2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CFEM PF05730.6 KFX91894.1 - 2.6e-08 33.5 10.3 2.6e-08 33.5 7.1 2.0 2 0 0 2 2 2 1 CFEM domain Zn_clus PF00172.13 KFX91894.1 - 0.00033 20.4 11.2 0.00066 19.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX91895.1 - 1.9e-41 141.9 59.1 1.3e-40 139.2 40.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX91895.1 - 1.5e-12 46.5 20.7 2.4e-12 45.8 14.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KFX91895.1 - 0.009 15.7 4.2 0.009 15.7 2.9 2.3 3 0 0 3 3 3 1 MFS_1 like family Ribosomal_L11_N PF03946.9 KFX91896.1 - 0.063 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Pkinase PF00069.20 KFX91897.1 - 3.8e-30 104.9 0.0 5.1e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91897.1 - 2e-10 40.1 0.0 0.00049 19.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 KFX91897.1 - 0.00039 19.8 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Sod_Cu PF00080.15 KFX91898.1 - 1.4e-44 151.7 5.1 1.6e-44 151.4 3.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Tox-HNH-EHHH PF15657.1 KFX91898.1 - 0.37 10.9 4.1 0.088 12.9 0.7 1.7 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins NAD_binding_10 PF13460.1 KFX91928.1 - 2.6e-13 50.4 0.4 4.7e-13 49.5 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX91928.1 - 0.0082 15.5 0.0 0.0098 15.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KFX91928.1 - 0.025 14.3 0.0 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.8 KFX91928.1 - 0.079 12.2 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DUF4395 PF14340.1 KFX91935.1 - 0.12 12.3 0.0 0.87 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF3698 PF12479.3 KFX91936.1 - 8.4 6.5 5.9 6.6 6.8 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) DUF4071 PF13281.1 KFX91937.1 - 0.12 11.1 0.3 0.14 10.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Abhydrolase_6 PF12697.2 KFX91941.1 - 1.7e-18 67.3 0.0 2.5e-18 66.8 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX91941.1 - 0.00014 21.4 0.0 0.00066 19.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KFX91941.1 - 0.00087 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase DUF1057 PF06342.7 KFX91941.1 - 0.015 14.0 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) PRP4 PF08799.6 KFX91942.1 - 2.5e-12 45.8 0.8 4.8e-12 44.9 0.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Med13_C PF06333.7 KFX91944.1 - 7.9e-96 321.1 0.0 1.5e-95 320.2 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KFX91944.1 - 2.9e-10 39.4 0.2 2.9e-10 39.4 0.1 2.5 2 1 0 2 2 2 1 Mediator complex subunit 13 N-terminal PNP_UDP_1 PF01048.15 KFX91945.1 - 7.4e-40 136.3 0.3 8.9e-40 136.1 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily zf-RING_4 PF14570.1 KFX91946.1 - 3.4e-19 68.1 12.1 5.7e-19 67.4 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KFX91946.1 - 5e-07 29.2 0.0 2.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KFX91946.1 - 2.7e-06 26.9 6.8 4.8e-06 26.1 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 KFX91946.1 - 0.00015 21.5 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KFX91946.1 - 0.00023 20.4 3.8 0.00023 20.4 2.6 3.1 2 0 0 2 2 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KFX91946.1 - 0.00072 19.3 9.1 0.0012 18.5 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain RRM_6 PF14259.1 KFX91946.1 - 0.0073 16.2 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 KFX91946.1 - 0.023 14.4 4.2 0.046 13.4 2.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM_2 PF14605.1 KFX91946.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.20 KFX91946.1 - 0.11 12.1 9.9 0.22 11.2 6.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFX91946.1 - 0.16 11.8 4.1 0.34 10.8 2.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger SET_assoc PF11767.3 KFX91946.1 - 0.26 10.6 0.0 0.57 9.5 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-RING_5 PF14634.1 KFX91946.1 - 0.44 10.3 10.4 0.76 9.5 7.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX91946.1 - 0.47 10.5 10.5 0.87 9.6 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KFX91946.1 - 1.7 8.4 7.4 0.3 10.8 2.3 1.9 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.11 KFX91946.1 - 1.9 8.4 13.9 0.014 15.3 2.7 2.7 3 1 0 3 3 3 0 FYVE-type zinc finger Prok-RING_4 PF14447.1 KFX91946.1 - 4.7 6.8 9.0 1.2 8.7 3.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Complex1_30kDa PF00329.14 KFX91947.1 - 3.3e-37 126.8 0.1 5e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1256 PF06866.6 KFX91948.1 - 0.036 13.2 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) Reo_sigmaC PF04582.7 KFX91953.1 - 6.8 5.7 28.8 0.9 8.6 0.3 3.9 2 1 2 4 4 4 0 Reovirus sigma C capsid protein NUC153 PF08159.7 KFX91955.1 - 4.4e-14 51.7 2.2 8.3e-14 50.8 1.5 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KFX91955.1 - 6.1e-05 22.7 0.2 0.0098 15.7 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Sugar_tr PF00083.19 KFX91957.1 - 1.4e-66 224.9 12.9 1.7e-66 224.6 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91957.1 - 2.1e-22 79.3 20.9 4.5e-22 78.2 14.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX91957.1 - 0.00029 19.1 2.9 0.0004 18.7 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFX91957.1 - 0.027 12.8 14.2 0.013 13.9 2.3 2.6 1 1 1 2 2 2 0 MFS/sugar transport protein FAD_binding_3 PF01494.14 KFX91958.1 - 5.4e-27 94.7 0.0 9.4e-27 93.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX91958.1 - 4.1e-10 39.0 4.0 2.7e-08 33.1 0.9 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX91958.1 - 3.8e-08 33.2 0.3 9.9e-08 31.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX91958.1 - 5.2e-06 25.6 0.2 3e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX91958.1 - 7.1e-06 25.8 0.6 0.38 10.5 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX91958.1 - 1e-05 25.8 0.4 0.016 15.5 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX91958.1 - 2.4e-05 22.9 0.3 0.0022 16.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KFX91958.1 - 3.2e-05 22.9 0.4 7.1e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KFX91958.1 - 0.00057 19.0 0.1 0.0011 18.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFX91958.1 - 0.00062 19.6 0.4 0.0011 18.8 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX91958.1 - 0.0018 17.2 0.5 0.0065 15.3 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFX91958.1 - 0.0018 16.9 0.4 0.61 8.6 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KFX91958.1 - 0.0093 16.0 0.6 0.069 13.2 0.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX91958.1 - 0.011 15.1 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 KFX91958.1 - 0.028 13.4 0.0 6 5.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFX91958.1 - 0.057 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KFX91958.1 - 0.058 13.0 1.2 0.087 12.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFX91958.1 - 0.16 12.0 0.2 0.65 10.0 0.0 2.1 3 0 0 3 3 2 0 TrkA-N domain Glyco_hydro_43 PF04616.9 KFX91959.1 - 2.6e-43 148.1 4.3 3.7e-43 147.6 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BAT2_N PF07001.6 KFX91960.1 - 0.015 15.6 5.9 0.031 14.6 4.1 1.5 1 0 0 1 1 1 0 BAT2 N-terminus NmrA PF05368.8 KFX91962.1 - 4.8e-25 88.1 0.0 6e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX91962.1 - 3.2e-10 40.3 0.4 3.1e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 KFX91962.1 - 0.032 14.1 0.4 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KFX91962.1 - 0.034 13.0 0.2 2 7.2 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Glyco_trans_4_4 PF13579.1 KFX91962.1 - 0.04 14.0 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain 3Beta_HSD PF01073.14 KFX91962.1 - 0.042 12.5 0.2 0.064 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFX91962.1 - 0.073 12.7 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 KFX91962.1 - 0.12 11.7 0.4 0.3 10.4 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KFX91963.1 - 6.9e-15 54.6 0.1 1.2e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91963.1 - 9.7e-08 31.7 9.6 1.7e-07 31.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KFX91964.1 - 1.5e-24 87.1 0.0 2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX91964.1 - 4.4e-14 52.6 0.0 7.4e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX91964.1 - 3.4e-06 26.8 0.0 6.4e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SKG6 PF08693.5 KFX91965.1 - 5.9e-07 28.6 0.1 1.2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 KFX91965.1 - 0.023 14.4 1.1 0.06 13.0 0.7 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 Gly-zipper_Omp PF13488.1 KFX91965.1 - 0.035 13.7 4.2 3 7.5 0.1 2.2 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.1 KFX91965.1 - 0.27 10.9 5.8 1.5 8.5 4.0 2.0 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Scm3 PF10384.4 KFX91966.1 - 7.2e-21 73.4 0.1 7.2e-21 73.4 0.1 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 Clr5 PF14420.1 KFX91966.1 - 9.1e-11 41.4 0.2 1.5e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Clr5 domain Myb_DNA-bind_2 PF08914.6 KFX91966.1 - 0.0071 16.1 1.2 0.018 14.8 0.6 2.0 2 0 0 2 2 2 1 Rap1 Myb domain LCAT PF02450.10 KFX91969.1 - 5.6e-95 318.5 0.0 8.3e-95 318.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 KFX91969.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 KFX91969.1 - 0.008 15.5 0.3 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 2) Imm2 PF14426.1 KFX91969.1 - 0.059 13.3 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm2 PGAP1 PF07819.8 KFX91969.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Acetyltransf_1 PF00583.19 KFX91970.1 - 5.6e-18 64.7 0.0 7.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFX91970.1 - 3.9e-09 36.1 0.0 7.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFX91970.1 - 9.9e-09 35.3 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX91970.1 - 3.2e-08 33.6 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX91970.1 - 3.5e-07 30.4 0.0 4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFX91970.1 - 1.1e-06 28.5 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX91970.1 - 6.1e-05 22.8 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX91970.1 - 0.0017 18.1 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF1917 PF08939.5 KFX91971.1 - 5e-64 216.3 0.0 5.8e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) WD40 PF00400.27 KFX91972.1 - 6e-12 44.9 4.4 0.0057 16.4 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KFX91973.1 - 5.1e-14 51.6 0.1 1.5e-13 50.1 0.1 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91973.1 - 6.9e-07 29.0 12.5 1.2e-06 28.3 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEMspv1-c74-12 PF11044.3 KFX91974.1 - 0.016 14.7 0.3 0.029 13.9 0.1 1.6 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Sec23_trunk PF04811.10 KFX91975.1 - 3.8e-70 236.0 0.0 5.4e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFX91975.1 - 1.1e-23 82.5 0.1 1.6e-22 78.8 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFX91975.1 - 3.9e-18 65.7 0.0 7.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFX91975.1 - 8.3e-18 63.6 5.1 1.4e-17 62.8 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFX91975.1 - 6.3e-08 32.2 0.0 1.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Sporozoite_P67 PF05642.6 KFX91975.1 - 1.8 6.3 6.7 3.1 5.5 4.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COG6 PF06419.6 KFX91976.1 - 1.5e-230 766.5 12.4 1.7e-230 766.4 8.6 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 KFX91976.1 - 0.00057 19.7 0.5 0.0044 16.8 0.1 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3620 PF12281.3 KFX91976.1 - 0.019 14.6 0.3 0.066 12.9 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3620) Reprolysin_4 PF13583.1 KFX91976.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Abi_C PF14355.1 KFX91976.1 - 0.11 12.4 0.1 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Abortive infection C-terminus DASH_Dam1 PF08653.5 KFX91976.1 - 1.7 8.4 4.1 15 5.4 0.0 4.1 5 0 0 5 5 5 0 DASH complex subunit Dam1 AAA PF00004.24 KFX91977.1 - 4.5e-38 130.4 0.0 2.5e-37 128.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX91977.1 - 7.1e-07 29.4 0.2 0.00011 22.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFX91977.1 - 1.2e-06 27.7 0.0 0.00012 21.2 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 KFX91977.1 - 8.9e-06 25.5 0.0 0.00012 21.8 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.1 KFX91977.1 - 0.00014 21.8 2.8 0.0019 18.2 0.4 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 KFX91977.1 - 0.0005 19.7 0.0 0.2 11.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFX91977.1 - 0.00081 18.2 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KFX91977.1 - 0.0015 18.2 0.0 0.0065 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFX91977.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 KFX91977.1 - 0.0027 16.6 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KFX91977.1 - 0.0037 16.9 0.7 0.026 14.2 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain Mg_chelatase PF01078.16 KFX91977.1 - 0.005 16.0 0.9 0.0082 15.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KFX91977.1 - 0.0076 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFX91977.1 - 0.01 15.6 0.1 0.032 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KFX91977.1 - 0.012 15.4 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX91977.1 - 0.014 15.3 0.3 0.18 11.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KFX91977.1 - 0.023 15.5 0.0 0.13 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX91977.1 - 0.031 13.6 0.2 0.27 10.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KFX91977.1 - 0.032 13.8 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFX91977.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFX91977.1 - 0.14 11.3 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KFX91977.1 - 0.14 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 KFX91977.1 - 0.21 11.0 0.0 0.59 9.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Ribosomal_S17 PF00366.15 KFX91978.1 - 1.3e-08 34.7 0.8 1.3e-08 34.7 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 WSN PF02206.13 KFX91978.1 - 0.0048 16.6 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function Peptidase_M15_3 PF08291.6 KFX91978.1 - 0.046 13.5 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase M15 GRIM-19 PF06212.7 KFX91979.1 - 1.6e-21 76.3 0.0 3.1e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 KFX91980.1 - 2.5e-34 118.4 0.0 9.8e-25 87.2 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DUF1230 PF06799.6 KFX91981.1 - 0.00095 19.0 1.1 0.0012 18.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1230) Acetyltransf_7 PF13508.1 KFX91982.1 - 3.4e-06 27.1 0.1 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX91982.1 - 1.8e-05 24.6 0.2 5.4e-05 23.1 0.2 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX91982.1 - 0.00019 21.5 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX91982.1 - 0.00092 18.9 0.1 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3472 PF11958.3 KFX91983.1 - 9.2e-14 52.1 1.5 1.2e-13 51.8 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Melibiase PF02065.13 KFX91984.1 - 1.6e-10 40.2 0.0 2.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 KFX91984.1 - 1.2e-08 35.0 3.2 2.6e-08 33.9 2.2 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Fig1 PF12351.3 KFX91986.1 - 5.2e-55 186.1 6.5 5.2e-55 186.1 4.5 2.1 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KFX91986.1 - 3.4e-09 36.5 12.0 4.5e-09 36.1 8.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family SPASM PF13186.1 KFX91986.1 - 0.052 13.8 0.1 0.084 13.2 0.0 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain DUF898 PF05987.8 KFX91986.1 - 0.1 11.4 15.1 0.0089 14.9 5.8 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF1673 PF07895.6 KFX91986.1 - 6.3 6.2 8.0 1.3 8.5 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) HSF_DNA-bind PF00447.12 KFX91987.1 - 5.1e-38 129.4 0.8 1.1e-37 128.3 0.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KFX91987.1 - 1.3e-19 70.2 0.1 2.5e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.20 KFX91992.1 - 1.4e-73 247.2 0.0 1.9e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91992.1 - 3.1e-31 108.3 0.0 4.4e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX91992.1 - 0.001 18.1 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFX91992.1 - 0.0037 16.3 0.1 0.0062 15.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX91992.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFX91992.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Homeobox_KN PF05920.6 KFX92004.1 - 4.8e-13 48.5 0.2 1.4e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFX92004.1 - 2.9e-06 26.7 0.5 8.5e-06 25.2 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KFX92004.1 - 0.0044 17.2 23.8 0.048 14.0 1.8 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX92004.1 - 0.023 15.0 20.5 1.8 9.0 1.5 4.7 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.2 KFX92004.1 - 0.25 11.6 9.0 11 6.4 0.7 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type GTP_EFTU PF00009.22 KFX92006.1 - 1.1e-39 135.8 0.0 1.9e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFX92006.1 - 4.5e-26 90.4 0.1 1.5e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 KFX92006.1 - 9.3e-18 63.8 0.1 2.6e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX92006.1 - 3.1e-10 40.0 0.1 1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KFX92006.1 - 0.02 14.4 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KFX92006.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 KFX92007.1 - 4.7e-12 45.6 0.7 7.8e-12 44.9 0.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KFX92007.1 - 8.6e-10 38.4 0.0 1.6e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 PX domain CCT_2 PF09425.5 KFX92007.1 - 0.2 11.2 3.7 6.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Divergent CCT motif SAP PF02037.22 KFX92008.1 - 2.5e-13 49.1 0.2 5.3e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain Pribosyltran_N PF13793.1 KFX92009.1 - 2e-41 140.3 0.1 7e-39 132.1 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KFX92009.1 - 4.1e-33 114.6 0.0 3.4e-28 98.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KFX92009.1 - 3.4e-05 23.5 0.0 0.0012 18.5 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain XPG_I_2 PF12813.2 KFX92010.1 - 1.4e-61 208.1 0.0 2.5e-61 207.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KFX92010.1 - 0.0016 18.4 0.0 0.0046 16.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region Pterin_bind PF00809.17 KFX92010.1 - 0.0071 15.7 0.0 0.15 11.3 0.0 2.8 3 1 1 4 4 4 1 Pterin binding enzyme AATF-Che1 PF13339.1 KFX92010.1 - 0.18 11.9 2.7 0.16 12.0 0.6 1.9 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF383 PF04063.9 KFX92012.1 - 1.4e-69 233.5 0.0 6.1e-69 231.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KFX92012.1 - 3.6e-21 74.4 2.7 3.9e-21 74.3 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 KFX92012.1 - 0.04 14.1 0.6 1.1 9.6 0.1 3.1 2 1 0 2 2 2 0 HEAT repeats PLAC8 PF04749.12 KFX92014.1 - 1.2e-17 64.3 13.6 1.6e-17 64.0 9.4 1.1 1 0 0 1 1 1 1 PLAC8 family PepSY_TM_2 PF13703.1 KFX92014.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Amidohydro_1 PF01979.15 KFX92020.1 - 1.9e-31 109.9 0.0 2.2e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX92020.1 - 3.6e-06 26.4 0.1 6.7e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family YopE_N PF09020.5 KFX92022.1 - 0.024 14.6 2.7 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 YopE, N terminal Peptidase_M28 PF04389.12 KFX92023.1 - 1.2e-34 119.5 0.0 1.7e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 SKG6 PF08693.5 KFX92024.1 - 0.0076 15.5 1.0 0.0076 15.5 0.7 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Kelch_5 PF13854.1 KFX92024.1 - 0.025 14.5 0.0 0.025 14.5 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 KFX92024.1 - 0.14 11.9 3.3 2.8 7.8 0.1 3.4 3 0 0 3 3 3 0 Kelch motif AA_permease PF00324.16 KFX92025.1 - 4.4e-123 411.1 38.2 5.1e-123 410.9 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX92025.1 - 8.3e-30 103.6 46.1 1e-29 103.3 31.9 1.1 1 0 0 1 1 1 1 Amino acid permease zf-His_Me_endon PF05551.6 KFX92026.1 - 0.00036 20.4 0.5 0.0012 18.8 0.4 1.8 1 1 0 1 1 1 1 Zinc-binding loop region of homing endonuclease HNH_3 PF13392.1 KFX92026.1 - 0.049 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease DUF2360 PF10152.4 KFX92027.1 - 1 9.6 4.4 1.1 9.5 3.1 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) EXOSC1 PF10447.4 KFX92030.1 - 1.4e-17 63.3 0.3 1.9e-17 62.9 0.2 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Annexin PF00191.15 KFX92034.1 - 3.1e-72 238.3 5.8 3.5e-19 68.4 0.0 4.2 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 KFX92034.1 - 0.023 14.8 0.7 4 7.7 0.0 3.5 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Myosin_tail_1 PF01576.14 KFX92038.1 - 0.00044 18.1 1.1 0.00055 17.7 0.8 1.1 1 0 0 1 1 1 1 Myosin tail DivIC PF04977.10 KFX92038.1 - 0.0028 17.0 0.5 1.1 8.8 0.1 2.3 2 0 0 2 2 2 2 Septum formation initiator DUF2802 PF10975.3 KFX92038.1 - 0.012 15.3 4.2 0.51 10.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Viral_P18 PF04521.8 KFX92038.1 - 0.061 12.7 1.0 3.4 7.1 0.1 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CENP-F_leu_zip PF10473.4 KFX92038.1 - 0.065 13.0 2.7 0.13 12.1 1.9 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 KFX92038.1 - 0.1 12.4 0.5 7.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 KFX92038.1 - 0.17 12.0 1.6 3.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DegS PF05384.6 KFX92038.1 - 0.18 10.9 3.2 4.2 6.5 0.3 2.1 2 0 0 2 2 2 0 Sensor protein DegS Laminin_II PF06009.7 KFX92038.1 - 0.22 11.2 4.1 2.8 7.6 0.2 2.1 1 1 0 2 2 2 0 Laminin Domain II P4Ha_N PF08336.6 KFX92038.1 - 0.22 11.3 2.4 0.5 10.1 0.3 1.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fib_alpha PF08702.5 KFX92038.1 - 0.26 11.4 1.9 6.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 KFX92038.1 - 0.3 11.4 4.2 6.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin FlaC_arch PF05377.6 KFX92038.1 - 0.33 10.8 3.0 7.4 6.5 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 KFX92038.1 - 0.36 10.6 3.5 6.4 6.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KFX92038.1 - 0.4 11.0 4.1 2.9 8.2 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2205 PF10224.4 KFX92038.1 - 0.51 9.9 4.4 2.3 7.8 0.6 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Laminin_II PF06009.7 KFX92041.1 - 0.03 14.0 0.4 0.068 12.9 0.2 1.6 1 0 0 1 1 1 0 Laminin Domain II DMPK_coil PF08826.5 KFX92041.1 - 0.055 13.3 0.6 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like HR1 PF02185.11 KFX92041.1 - 0.061 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Hr1 repeat eIF3_N PF09440.5 KFX92041.1 - 0.15 12.2 1.1 0.35 11.0 0.1 1.9 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain adh_short PF00106.20 KFX92053.1 - 6.3e-07 29.4 6.3 1.7e-06 28.0 4.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX92053.1 - 0.0055 16.4 6.3 0.12 11.9 4.4 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX92053.1 - 0.15 12.0 0.9 0.2 11.6 0.6 1.1 1 0 0 1 1 1 0 NADH(P)-binding HI0933_like PF03486.9 KFX92053.1 - 0.22 9.9 1.2 0.29 9.5 0.9 1.1 1 0 0 1 1 1 0 HI0933-like protein Tim54 PF11711.3 KFX92059.1 - 3.2e-80 269.5 0.3 5.8e-80 268.7 0.2 1.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 KFX92060.1 - 6.3e-57 192.6 0.1 8e-40 136.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92060.1 - 2.4e-26 92.3 0.1 1e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX92060.1 - 7.7e-05 21.7 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX92060.1 - 0.00014 21.6 3.0 0.0039 16.9 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX92060.1 - 0.00055 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFX92060.1 - 0.04 12.7 0.1 0.064 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KFX92060.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KFX92060.1 - 0.28 10.5 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family zf-met PF12874.2 KFX92061.1 - 1.9e-05 24.6 0.6 3.8e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KFX92061.1 - 0.052 12.8 0.9 0.095 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.20 KFX92062.1 - 4.1e-17 61.6 0.3 8.2e-17 60.6 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KFX92062.1 - 2.7e-08 33.2 12.3 0.0035 16.9 0.5 4.8 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX92062.1 - 0.00031 20.4 10.0 0.12 12.1 0.2 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFX92062.1 - 0.003 17.3 14.5 0.51 10.5 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich Repeat zf-CCCH PF00642.19 KFX92062.1 - 0.0082 15.8 3.8 0.015 15.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_6 PF13516.1 KFX92062.1 - 0.13 12.4 13.6 12 6.3 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 KFX92062.1 - 1.8 9.0 9.4 5 7.7 0.3 5.4 7 0 0 7 7 7 0 Leucine rich repeat RNA_lig_T4_1 PF09511.5 KFX92063.1 - 1.9e-80 269.5 0.0 3e-80 268.8 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KFX92063.1 - 1.2e-74 250.8 0.1 1.8e-74 250.2 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KFX92063.1 - 2.6e-57 193.3 0.3 4.7e-57 192.4 0.2 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 KFX92063.1 - 0.0084 16.9 0.1 0.054 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.1 KFX92064.1 - 7e-12 45.1 0.1 1.8e-09 37.5 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX92064.1 - 1.5e-10 41.2 0.0 6.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFX92064.1 - 1.2e-06 28.7 0.1 7.6e-05 22.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92064.1 - 9.7e-05 21.9 0.0 0.0014 18.3 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFX92064.1 - 0.00049 20.0 0.3 0.044 14.0 0.1 3.2 4 0 0 4 4 4 1 Ankyrin repeat Peptidase_M17_N PF02789.12 KFX92064.1 - 0.099 12.3 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Ribonuc_P_40 PF08584.6 KFX92065.1 - 8.9e-68 228.3 0.0 1.2e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Zn_clus PF00172.13 KFX92085.1 - 8e-06 25.6 9.2 1.7e-05 24.6 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX92085.1 - 0.05 12.4 0.1 0.12 11.2 0.1 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2039 PF10217.4 KFX92085.1 - 0.46 10.5 5.1 0.52 10.3 1.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Mito_carr PF00153.22 KFX92086.1 - 9e-38 127.8 2.1 4.6e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 KFX92087.1 - 4.4e-66 219.2 10.1 1.7e-23 82.7 0.4 3.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92087.1 - 6.1e-48 158.3 22.0 5.2e-07 29.1 0.1 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KFX92087.1 - 3.9e-42 141.8 11.2 1.4e-09 38.2 0.0 5.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92087.1 - 3e-40 132.1 6.5 0.00012 21.9 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFX92087.1 - 2.6e-32 110.1 18.6 0.0001 22.4 0.1 7.9 1 1 7 8 8 8 7 Ankyrin repeats (many copies) DUF2384 PF09722.5 KFX92087.1 - 0.0032 17.2 0.1 2.6 7.9 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2384) FA PF08736.6 KFX92087.1 - 0.0068 16.1 0.1 0.61 9.9 0.0 2.8 3 0 0 3 3 3 1 FERM adjacent (FA) Shigella_OspC PF06128.6 KFX92087.1 - 0.061 12.8 0.0 15 4.9 0.0 2.8 1 1 2 3 3 3 0 Shigella flexneri OspC protein polyprenyl_synt PF00348.12 KFX92088.1 - 4.9e-37 127.1 0.0 8.6e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KFX92088.1 - 0.0014 17.9 0.1 0.061 12.5 0.0 2.5 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Tho2 PF11262.3 KFX92088.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Zw10 PF06248.8 KFX92089.1 - 6.3e-07 27.9 0.1 3.7e-06 25.3 0.1 2.0 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KFX92089.1 - 0.00071 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal LRR_4 PF12799.2 KFX92090.1 - 0.015 14.9 8.3 0.23 11.1 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFX92090.1 - 0.066 13.3 11.6 0.76 10.0 0.0 7.0 9 0 0 9 9 9 0 Leucine Rich repeat SNF2_N PF00176.18 KFX92091.1 - 3e-58 196.9 0.0 5.1e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX92091.1 - 1.7e-13 50.2 0.0 6.1e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KFX92091.1 - 9.5e-06 25.1 10.9 9.5e-06 25.1 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KFX92091.1 - 1.5e-05 24.8 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX92091.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 KFX92091.1 - 0.0057 16.6 10.5 0.0057 16.6 7.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 KFX92091.1 - 0.037 12.7 0.0 0.11 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF3881 PF12997.2 KFX92091.1 - 0.1 11.6 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) zf-RING_2 PF13639.1 KFX92091.1 - 3.8 7.4 25.0 0.039 13.7 9.5 2.5 2 0 0 2 2 2 0 Ring finger domain EVE PF01878.13 KFX92093.1 - 1.1e-32 113.0 0.1 1.2e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 EVE domain DUF1426 PF07234.6 KFX92097.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) DUF3506 PF12014.3 KFX92098.1 - 1.2e-48 164.3 0.0 7.4e-48 161.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KFX92098.1 - 0.00013 21.5 0.2 0.00024 20.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX92098.1 - 0.00065 19.2 0.6 0.0012 18.4 0.4 1.4 1 0 0 1 1 1 1 F-box domain DUF1769 PF08588.5 KFX92099.1 - 5.7e-25 87.0 0.2 1.2e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF4568 PF15132.1 KFX92099.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) ADH_zinc_N PF00107.21 KFX92100.1 - 1.7e-35 121.4 0.8 3e-35 120.5 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX92100.1 - 2.6e-11 44.5 0.0 5.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX92100.1 - 2.8e-05 23.8 0.0 7.1e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KFX92100.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain DUF2493 PF10686.4 KFX92100.1 - 0.0071 15.8 0.7 1 8.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2493) AlaDh_PNT_C PF01262.16 KFX92100.1 - 0.069 12.7 0.4 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CTD PF12815.2 KFX92101.1 - 1.5e-25 90.0 58.9 9.7e-23 80.9 24.1 5.0 2 1 2 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KFX92101.1 - 5e-25 87.0 0.1 9.1e-25 86.2 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KFX92101.1 - 4e-21 75.4 9.6 4e-21 75.4 6.7 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KFX92101.1 - 8.3e-09 34.8 12.3 0.0011 18.5 0.0 5.5 6 0 0 6 6 6 2 KOW motif Nucleo_P87 PF07267.6 KFX92101.1 - 7 5.1 17.9 12 4.3 12.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_6 PF12697.2 KFX92102.1 - 0.0007 19.5 0.0 0.00073 19.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFX92102.1 - 0.023 14.1 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFX92102.1 - 0.053 13.2 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX92102.1 - 0.092 11.9 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Copper-fist PF00649.13 KFX92110.1 - 2e-11 42.8 0.5 2e-11 42.8 0.3 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain Abhydrolase_3 PF07859.8 KFX92111.1 - 4e-40 137.6 0.0 4.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX92111.1 - 4e-08 32.4 0.7 8.3e-08 31.3 0.5 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFX92111.1 - 0.0013 17.9 0.2 0.2 10.8 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DUF2974 PF11187.3 KFX92111.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KFX92111.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX92111.1 - 0.059 12.8 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 KFX92111.1 - 0.094 11.5 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme E1-E2_ATPase PF00122.15 KFX92112.1 - 2.1e-49 167.6 0.0 7.6e-49 165.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX92112.1 - 3.8e-40 138.6 0.2 8.2e-40 137.5 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFX92112.1 - 7.1e-37 125.3 0.0 4.7e-11 42.6 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KFX92112.1 - 4e-17 63.0 0.0 1e-16 61.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX92112.1 - 1.5e-05 24.6 0.1 0.0019 17.7 0.1 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 KFX92112.1 - 0.15 12.0 0.8 94 3.0 0.0 4.4 5 0 0 5 5 5 0 Glutathione-dependent formaldehyde-activating enzyme DUF4066 PF13278.1 KFX92119.1 - 1.9e-17 63.0 0.1 2.2e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX92119.1 - 0.00039 19.9 0.0 0.00046 19.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF883 PF05957.8 KFX92119.1 - 0.084 13.2 0.4 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.20 KFX92120.1 - 1.2e-20 73.7 0.0 2e-18 66.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92120.1 - 4.8e-08 32.3 0.0 1.6e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pyr_redox_3 PF13738.1 KFX92121.1 - 1e-16 61.6 0.2 2.6e-16 60.3 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX92121.1 - 2.6e-12 45.7 0.1 1e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFX92121.1 - 2.9e-08 33.0 0.0 2.4e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX92121.1 - 3.7e-08 33.4 0.0 0.00041 20.3 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX92121.1 - 8.3e-05 22.5 0.0 0.04 13.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX92121.1 - 0.002 18.4 0.1 0.14 12.5 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX92121.1 - 0.013 14.4 0.0 0.37 9.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KFX92121.1 - 0.017 15.3 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 KFX92121.1 - 0.018 15.0 2.2 22 5.1 0.1 4.4 5 0 0 5 5 5 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KFX92121.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KFX92121.1 - 0.25 10.2 0.9 31 3.2 0.1 3.3 2 1 0 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.11 KFX92122.1 - 1.1e-13 50.5 32.8 1.8e-13 49.9 22.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFX92122.1 - 2.2e-10 40.2 5.2 2.2e-10 40.2 3.6 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 GSK-3_bind PF05350.7 KFX92129.1 - 1.4 8.3 5.4 1.6 8.0 3.7 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding DUF1279 PF06916.8 KFX92131.1 - 9.3e-12 45.0 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) TrbH PF07283.6 KFX92131.1 - 0.034 14.0 0.0 0.46 10.3 0.0 1.9 1 1 1 2 2 2 0 Conjugal transfer protein TrbH SET PF00856.23 KFX92136.1 - 5.3e-17 62.5 0.4 5.3e-17 62.5 0.2 3.0 3 2 0 3 3 3 1 SET domain B12D PF06522.6 KFX92137.1 - 0.0027 17.3 0.0 0.0059 16.2 0.0 1.6 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PRP21_like_P PF12230.3 KFX92138.1 - 7.3e-56 189.2 22.6 4.7e-55 186.6 15.7 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KFX92138.1 - 8.8e-39 130.9 2.2 2e-18 65.7 0.2 2.6 2 0 0 2 2 2 2 Surp module PMT PF02366.13 KFX92139.1 - 7.5e-73 244.8 15.1 1.2e-72 244.2 10.5 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFX92139.1 - 7.4e-54 182.1 0.0 1.2e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 MIR domain Mito_carr PF00153.22 KFX92140.1 - 6.6e-74 243.7 2.1 2.4e-24 84.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GPI-anchored PF10342.4 KFX92145.1 - 6.8e-13 48.9 0.1 6.8e-13 48.9 0.1 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 KFX92146.1 - 2.6e-20 72.6 1.1 2.6e-20 72.6 0.8 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family IER PF05760.7 KFX92146.1 - 0.53 10.1 6.8 0.59 10.0 4.7 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF3827 PF12877.2 KFX92146.1 - 2.1 6.3 6.2 2.7 5.9 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Mitofilin PF09731.4 KFX92146.1 - 3.3 6.2 7.8 3.8 6.0 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 KFX92146.1 - 3.6 5.9 10.1 4.4 5.6 7.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Presenilin PF01080.12 KFX92146.1 - 8.9 5.0 10.0 11 4.6 6.9 1.1 1 0 0 1 1 1 0 Presenilin Opy2 PF09463.5 KFX92149.1 - 1.2e-07 31.6 25.3 2e-07 30.9 17.5 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KFX92149.1 - 0.00093 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain P12 PF12669.2 KFX92149.1 - 0.06 13.5 0.8 0.06 13.5 0.6 2.8 2 1 0 2 2 2 0 Virus attachment protein p12 family Chitin_synth_1 PF01644.12 KFX92150.1 - 3.9e-69 231.6 0.1 5.9e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFX92150.1 - 1.1e-28 98.6 0.1 2.9e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFX92150.1 - 5.7e-24 84.4 0.5 3.2e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFX92150.1 - 6.1e-11 42.3 0.0 6.1e-11 42.3 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFX92150.1 - 9.9e-08 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3987 PF13148.1 KFX92150.1 - 0.37 9.3 0.4 0.56 8.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) UQ_con PF00179.21 KFX92151.1 - 1.4e-38 131.4 0.0 1.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX92151.1 - 0.044 13.5 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Acyl-thio_N PF12590.3 KFX92151.1 - 0.056 13.9 0.2 0.085 13.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-ATP thioesterase UEV PF05743.8 KFX92151.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain IlvN PF07991.7 KFX92152.1 - 9.2e-45 151.9 0.1 1.4e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KFX92152.1 - 2e-44 151.0 0.0 2.9e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Pkinase PF00069.20 KFX92159.1 - 6.2e-35 120.5 0.0 3.5e-34 118.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92159.1 - 2e-23 82.7 0.0 6.3e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX92159.1 - 0.033 13.9 0.2 0.43 10.2 0.2 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family SWI-SNF_Ssr4 PF08549.5 KFX92168.1 - 1.3e-169 565.6 9.4 1.5e-169 565.5 6.5 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) HNH_2 PF13391.1 KFX92171.1 - 4.2e-10 39.2 0.0 7.8e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Beta-lactamase PF00144.19 KFX92172.1 - 7.3e-39 133.6 0.1 9.6e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 KFX92173.1 - 1.7e-09 36.7 1.2 2.2e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92173.1 - 2.4e-07 30.5 10.1 4e-07 29.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KFX92174.1 - 1.1e-47 162.5 0.0 1.6e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 IBN_N PF03810.14 KFX92175.1 - 2.4e-08 33.7 0.0 2.1e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFX92175.1 - 0.0074 16.2 0.0 0.076 12.9 0.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KFX92175.1 - 0.18 11.9 1.8 44 4.5 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HORMA PF02301.13 KFX92176.1 - 7.3e-23 81.1 0.0 9e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain CorA PF01544.13 KFX92179.1 - 8.4e-42 143.1 0.6 2.7e-41 141.5 0.4 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TBCA PF02970.11 KFX92180.1 - 1.5e-20 73.0 14.8 1.8e-20 72.8 9.9 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A D123 PF07065.9 KFX92180.1 - 0.016 14.2 2.0 0.018 14.1 1.4 1.1 1 0 0 1 1 1 0 D123 MHCassoc_trimer PF08831.5 KFX92180.1 - 0.032 14.0 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF3841 PF12952.2 KFX92180.1 - 0.049 13.0 0.7 0.056 12.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) DUF342 PF03961.8 KFX92180.1 - 0.31 9.3 8.8 0.37 9.1 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1978 PF09321.5 KFX92180.1 - 0.42 10.0 12.5 0.38 10.1 7.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) Fib_alpha PF08702.5 KFX92180.1 - 0.52 10.4 3.6 0.72 9.9 2.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DASH_Spc19 PF08287.6 KFX92180.1 - 0.58 9.7 9.1 0.68 9.5 5.7 1.6 1 1 0 1 1 1 0 Spc19 YkyA PF10368.4 KFX92180.1 - 0.59 9.4 17.3 0.086 12.1 8.1 1.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Syntaxin PF00804.20 KFX92180.1 - 0.63 10.2 6.9 1.3 9.2 4.8 1.5 1 1 0 1 1 1 0 Syntaxin CENP-Q PF13094.1 KFX92180.1 - 0.66 9.9 12.1 1.6 8.7 8.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CDC37_N PF03234.9 KFX92180.1 - 0.69 10.2 7.5 1.1 9.5 5.2 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4239 PF14023.1 KFX92180.1 - 0.85 8.9 3.5 1.1 8.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) V_ATPase_I PF01496.14 KFX92180.1 - 0.97 7.2 6.3 1.1 7.0 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KFX92180.1 - 1.2 8.1 13.5 0.69 8.8 8.4 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF3435 PF11917.3 KFX92180.1 - 1.4 7.5 6.9 1.6 7.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) HSP70 PF00012.15 KFX92180.1 - 1.5 6.6 10.3 1.7 6.4 7.2 1.0 1 0 0 1 1 1 0 Hsp70 protein IncA PF04156.9 KFX92180.1 - 1.6 8.3 13.8 2.3 7.7 9.5 1.3 1 1 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 KFX92180.1 - 2.1 7.4 7.5 2.6 7.1 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS6_N PF14661.1 KFX92180.1 - 2.4 7.4 7.8 3.1 7.0 5.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF883 PF05957.8 KFX92180.1 - 3 8.2 8.3 0.48 10.8 1.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FlgN PF05130.7 KFX92180.1 - 3 8.0 11.3 0.83 9.9 5.5 1.6 1 1 1 2 2 2 0 FlgN protein TMPIT PF07851.8 KFX92180.1 - 4.8 6.1 5.5 5.4 5.9 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein ERM PF00769.14 KFX92180.1 - 5 6.5 19.6 6.2 6.2 13.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4463 PF14703.1 KFX92180.1 - 8.3 7.0 10.7 58 4.3 7.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) DivIVA PF05103.8 KFX92180.1 - 8.9 6.3 18.8 3.8 7.5 5.1 2.0 1 1 1 2 2 2 0 DivIVA protein Bombinin PF05298.6 KFX92183.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Bombinin Fungal_trans PF04082.13 KFX92184.1 - 9e-09 34.5 0.1 1.3e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92184.1 - 1.8e-06 27.7 10.0 3.9e-06 26.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PWI PF01480.12 KFX92185.1 - 4.5e-09 36.2 0.1 1.2e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 KFX92185.1 - 0.15 11.6 0.0 0.49 10.0 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF445 PF04286.7 KFX92185.1 - 0.77 9.2 15.7 0.16 11.4 8.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Ribosomal_S21 PF01165.15 KFX92186.1 - 6e-11 41.6 1.9 1.4e-10 40.4 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S21 Rhodanese PF00581.15 KFX92186.1 - 3.9e-09 36.8 0.1 6.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain BAR_2 PF10455.4 KFX92188.1 - 6.5e-16 58.0 0.1 8.1e-16 57.7 0.1 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFX92188.1 - 9.3e-08 31.8 0.1 1.1e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 BAR domain Zn_clus PF00172.13 KFX92192.1 - 1.1e-09 38.0 10.2 1.7e-09 37.4 7.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX92192.1 - 8.6e-06 24.5 0.1 1.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 KFX92193.1 - 5.8e-68 228.2 0.0 7.6e-68 227.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Kinesin PF00225.18 KFX92195.1 - 2.1e-80 269.9 0.0 3.3e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 KFX92195.1 - 0.0012 18.4 0.4 0.48 10.2 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.2 KFX92195.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 KFX92195.1 - 0.074 13.2 0.2 1.1 9.5 0.1 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain UCH PF00443.24 KFX92200.1 - 5e-62 209.4 0.0 6.6e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX92200.1 - 1.6e-30 106.5 0.2 1.6e-22 80.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KFX92200.1 - 0.012 14.9 4.9 0.19 10.9 1.4 2.4 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Methyltransf_23 PF13489.1 KFX92208.1 - 3.6e-10 39.7 0.0 5.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX92208.1 - 3.1e-09 37.2 0.0 6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX92208.1 - 1.5e-05 25.3 0.0 6.5e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX92208.1 - 1.5e-05 24.5 0.0 0.00012 21.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX92208.1 - 0.00017 20.8 0.0 0.00063 18.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFX92208.1 - 0.00028 21.1 0.0 0.0019 18.5 0.0 2.4 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92208.1 - 0.0014 19.2 0.0 0.0066 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX92208.1 - 0.095 11.7 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase KH_1 PF00013.24 KFX92210.1 - 0.008 15.8 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KFX92210.1 - 0.019 14.5 0.1 0.096 12.3 0.0 2.2 3 0 0 3 3 3 0 KH domain DEAD PF00270.24 KFX92213.1 - 1.8e-45 154.4 0.0 1.5e-44 151.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX92213.1 - 6.9e-24 83.5 0.0 2.1e-23 81.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFX92213.1 - 0.00052 18.8 0.0 0.00081 18.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFX92213.1 - 0.0012 18.7 0.0 0.026 14.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box PF00505.14 KFX92214.1 - 3.9e-13 49.4 2.9 3.4e-09 36.8 0.3 3.6 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX92214.1 - 6.9e-11 42.3 1.2 4.1e-07 30.2 0.0 3.2 3 1 0 3 3 3 2 HMG-box domain HAT PF02184.11 KFX92215.1 - 2.3e-26 91.2 69.6 2.7e-12 46.2 1.1 14.1 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KFX92215.1 - 3.3e-21 73.8 28.0 0.0024 18.3 0.1 11.9 6 3 7 13 13 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 KFX92215.1 - 6.2e-21 74.5 2.3 1.9e-05 24.8 0.0 7.3 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFX92215.1 - 5.4e-20 71.5 17.6 0.03 14.9 0.0 8.9 9 1 1 10 10 10 6 Tetratricopeptide repeat Suf PF05843.9 KFX92215.1 - 9.9e-12 45.1 23.3 7.1e-05 22.6 0.7 6.0 2 1 4 6 6 6 3 Suppressor of forked protein (Suf) TPR_2 PF07719.12 KFX92215.1 - 2.1e-10 39.7 24.2 0.45 10.5 0.0 10.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92215.1 - 2.2e-08 33.6 9.8 0.052 13.2 0.2 6.9 6 2 2 8 8 8 2 TPR repeat U3_assoc_6 PF08640.6 KFX92215.1 - 2.6e-07 30.3 24.5 0.014 15.1 0.9 7.0 4 2 2 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 KFX92215.1 - 6.2e-06 26.0 27.3 0.23 11.4 0.0 9.3 9 2 1 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX92215.1 - 0.00057 19.8 7.8 0.048 13.8 0.1 5.3 7 0 0 7 7 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFX92215.1 - 0.00057 19.0 20.1 0.012 14.7 0.6 5.1 1 1 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX92215.1 - 0.00061 19.4 15.3 6 6.9 0.0 8.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX92215.1 - 0.0032 17.8 21.1 6.9 7.3 0.0 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX92215.1 - 0.0049 16.5 6.7 35 4.4 0.0 7.1 8 1 1 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFX92215.1 - 0.025 14.4 10.1 20 5.1 0.5 6.0 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.5 KFX92215.1 - 0.097 11.5 27.3 0.31 9.8 2.5 6.2 3 3 4 7 7 7 0 NRDE-2, necessary for RNA interference PBP1_TM PF14812.1 KFX92215.1 - 4.5 7.6 15.8 0.054 13.7 2.0 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_N_3 PF13417.1 KFX92216.1 - 1.5e-19 69.9 0.3 3.4e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX92216.1 - 2e-11 43.7 0.5 5.6e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX92216.1 - 4.7e-05 23.1 0.2 0.00012 21.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetate_kinase PF00871.12 KFX92217.1 - 1.7e-83 280.3 0.0 1e-64 218.4 0.0 2.0 1 1 1 2 2 2 2 Acetokinase family PetG PF02529.10 KFX92219.1 - 0.22 11.0 0.7 0.47 10.0 0.1 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF3602 PF12223.3 KFX92221.1 - 1.6e-14 54.0 15.4 1.5e-12 47.7 1.8 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF2149 PF09919.4 KFX92221.1 - 0.65 10.1 3.5 1.1 9.4 2.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) PNPase_C PF12111.3 KFX92221.1 - 1.6 8.0 5.8 0.35 10.0 0.8 2.3 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal DUF3712 PF12505.3 KFX92225.1 - 6.2e-20 71.4 1.6 6.2e-20 71.4 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) tRNA_bind PF01588.15 KFX92227.1 - 2.8e-21 75.1 0.1 1.5e-20 72.8 0.1 2.0 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KFX92227.1 - 6e-06 26.6 0.0 1.9e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX92227.1 - 0.0054 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 KFX92228.1 - 7.4e-28 97.1 0.0 2.8e-27 95.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92228.1 - 1.7e-09 37.3 8.9 3e-09 36.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 KFX92228.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) SEP PF08059.8 KFX92231.1 - 1e-23 83.3 0.2 1.9e-23 82.5 0.0 1.5 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 KFX92231.1 - 3.2e-10 39.9 0.0 4.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain Ank_2 PF12796.2 KFX92233.1 - 6.4e-107 350.1 16.3 4.7e-24 84.5 1.0 6.1 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92233.1 - 8.5e-77 249.3 4.0 9.7e-08 31.4 0.0 12.2 11 1 1 12 12 12 11 Ankyrin repeat Ank_3 PF13606.1 KFX92233.1 - 1.5e-62 201.2 3.9 3.6e-05 23.5 0.0 12.5 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KFX92233.1 - 1.3e-52 175.2 8.4 1.8e-10 41.0 0.0 9.3 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX92233.1 - 5.4e-44 147.2 5.3 5.3e-08 32.8 0.1 9.1 1 1 8 10 10 10 9 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFX92233.1 - 0.055 12.9 3.2 56 3.0 0.0 4.8 5 1 1 6 6 6 0 Shigella flexneri OspC protein Reductase_C PF14759.1 KFX92233.1 - 0.077 13.2 0.2 13 6.1 0.0 3.6 3 0 0 3 3 3 0 Reductase C-terminal Ank_2 PF12796.2 KFX92234.1 - 5.7e-15 55.4 0.0 1.1e-07 32.0 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX92234.1 - 9.7e-12 45.0 0.1 3.4e-06 27.4 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92234.1 - 3.3e-09 36.1 0.7 7.8e-08 31.8 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 KFX92234.1 - 1.9e-08 34.2 0.1 2e-07 30.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFX92234.1 - 4.3e-08 32.5 0.5 2.5e-07 30.1 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeat RabGAP-TBC PF00566.13 KFX92239.1 - 5.6e-32 110.9 0.0 8.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ORMDL PF04061.9 KFX92247.1 - 1.6e-60 202.5 4.6 2e-60 202.2 3.2 1.1 1 0 0 1 1 1 1 ORMDL family DUF543 PF04418.7 KFX92248.1 - 2.1e-25 88.4 0.0 5.3e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-CCHC PF00098.18 KFX92248.1 - 3.4e-06 26.7 25.1 0.066 13.1 2.7 4.6 4 0 0 4 4 4 4 Zinc knuckle Herpes_gE PF02480.11 KFX92249.1 - 0.016 13.4 0.0 0.017 13.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E LOH1CR12 PF10158.4 KFX92250.1 - 0.0007 19.3 2.1 0.00087 19.0 0.2 1.9 2 1 0 3 3 3 1 Tumour suppressor protein DUF948 PF06103.6 KFX92250.1 - 0.14 12.0 1.0 0.78 9.6 0.1 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MMR_HSR1_C PF08438.5 KFX92251.1 - 3.2e-31 107.7 0.0 6.5e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KFX92251.1 - 1.3e-18 67.0 0.0 2.9e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX92251.1 - 7.8e-10 38.2 0.1 1.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 KFX92251.1 - 0.0015 18.3 2.1 0.16 11.7 0.2 2.6 3 0 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KFX92251.1 - 0.0021 17.5 0.3 0.87 8.9 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFX92251.1 - 0.003 17.1 0.1 0.8 9.2 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein VirB8 PF04335.8 KFX92251.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 VirB8 protein KTI12 PF08433.5 KFX92251.1 - 0.089 11.9 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 KFX92251.1 - 0.1 12.8 0.1 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter SET PF00856.23 KFX92253.1 - 3e-07 30.8 0.0 6.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.13 KFX92254.1 - 3.2e-29 101.5 1.0 5.2e-29 100.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92254.1 - 1.7e-08 34.2 14.9 3.7e-08 33.1 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 KFX92254.1 - 0.1 12.9 3.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 0 Striatin family Spermine_synth PF01564.12 KFX92256.1 - 1.2e-100 335.4 0.0 1.6e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KFX92256.1 - 7.5e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX92256.1 - 0.0005 19.6 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KFX92256.1 - 0.0019 17.2 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 KFX92256.1 - 0.0084 16.5 0.5 0.1 13.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFX92256.1 - 0.034 13.3 0.1 0.13 11.4 0.0 1.8 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_30 PF05430.6 KFX92256.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Sporozoite_P67 PF05642.6 KFX92257.1 - 0.012 13.5 12.5 0.015 13.2 8.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KFX92257.1 - 1.3 6.8 9.8 1.7 6.4 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family ABC2_membrane_3 PF12698.2 KFX92257.1 - 1.5 7.8 3.0 1.8 7.5 2.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Mucin PF01456.12 KFX92257.1 - 1.8 8.3 32.1 3.7 7.3 22.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein FAD_binding_4 PF01565.18 KFX92258.1 - 8.9e-23 80.2 0.3 1.5e-22 79.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX92258.1 - 0.0028 17.5 0.1 0.006 16.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF2304 PF10066.4 KFX92259.1 - 4.3 7.2 13.8 0.3 10.9 1.3 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) BING4CT PF08149.6 KFX92260.1 - 9.3 5.8 7.1 7.3 6.1 2.5 2.5 2 0 0 2 2 2 0 BING4CT (NUC141) domain Ribosomal_L22e PF01776.12 KFX92261.1 - 7.2e-48 161.2 1.5 9.4e-48 160.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Tubulin PF00091.20 KFX92262.1 - 9.9e-73 244.5 0.0 1.5e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX92262.1 - 1.8e-46 157.2 0.1 3.6e-46 156.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Mito_carr PF00153.22 KFX92262.1 - 4.3e-42 141.7 3.2 9.9e-19 66.8 0.1 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein GDPD PF03009.12 KFX92262.1 - 7.5e-33 114.1 0.0 1.3e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.4 KFX92262.1 - 3.4e-07 30.3 0.0 6.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GDPD_2 PF13653.1 KFX92262.1 - 0.0017 18.4 0.2 0.0044 17.1 0.2 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PIG-F PF06699.6 KFX92263.1 - 2.3e-43 148.3 3.1 3.5e-43 147.7 2.1 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Translin PF01997.11 KFX92264.1 - 4e-52 176.7 0.0 4.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 KFX92264.1 - 0.041 13.6 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 GMP synthase C terminal domain PLU-1 PF08429.6 KFX92264.1 - 0.06 12.2 0.5 0.12 11.2 0.4 1.6 1 1 0 1 1 1 0 PLU-1-like protein DUF2411 PF10304.4 KFX92264.1 - 0.1 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Amino_oxidase PF01593.19 KFX92266.1 - 1.8e-33 116.3 0.0 4.2e-23 82.1 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Ank_2 PF12796.2 KFX92266.1 - 4.4e-25 87.8 0.6 2.1e-13 50.3 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX92266.1 - 2.6e-14 53.2 0.8 2.5e-08 34.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFX92266.1 - 3e-10 39.3 4.3 0.00014 21.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat NAD_binding_8 PF13450.1 KFX92266.1 - 1.1e-09 38.1 0.0 2.6e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ank_5 PF13857.1 KFX92266.1 - 4.1e-08 33.2 1.4 2.8e-06 27.3 0.2 3.4 2 1 2 4 4 3 2 Ankyrin repeats (many copies) DAO PF01266.19 KFX92266.1 - 1.3e-06 27.5 0.0 3.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ank_3 PF13606.1 KFX92266.1 - 1e-05 25.2 3.0 0.093 13.0 0.0 3.7 3 0 0 3 3 2 2 Ankyrin repeat Pyr_redox PF00070.22 KFX92266.1 - 0.00028 21.2 0.0 0.00084 19.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX92266.1 - 0.00035 20.6 0.0 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX92266.1 - 0.0007 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KFX92266.1 - 0.0028 16.7 0.3 0.0067 15.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFX92266.1 - 0.015 13.8 0.1 0.031 12.7 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFX92266.1 - 0.032 13.8 0.2 0.11 12.1 0.2 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2346 PF09803.4 KFX92266.1 - 0.043 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Pyr_redox_2 PF07992.9 KFX92266.1 - 0.044 13.6 0.5 0.11 12.3 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX92266.1 - 0.065 12.0 0.9 0.12 11.2 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KFX92266.1 - 0.069 12.2 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mnd1 PF03962.10 KFX92266.1 - 0.12 12.0 0.2 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Mnd1 family NAD_binding_7 PF13241.1 KFX92266.1 - 0.14 12.4 0.0 0.7 10.1 0.0 2.2 2 0 0 2 2 1 0 Putative NAD(P)-binding ABM PF03992.11 KFX92269.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TPR_12 PF13424.1 KFX92270.1 - 1.1e-07 31.7 7.4 3.4e-07 30.0 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX92270.1 - 6.7e-06 25.6 4.2 0.013 15.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFX92270.1 - 1.2e-05 25.4 3.1 0.011 16.1 0.1 3.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX92270.1 - 9.3e-05 21.9 1.8 0.4 10.5 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92270.1 - 0.0003 20.3 5.4 0.0022 17.5 0.3 3.6 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.1 KFX92270.1 - 0.0013 19.0 2.3 0.02 15.2 0.3 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX92270.1 - 0.02 14.9 0.2 0.067 13.3 0.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFX92270.1 - 0.022 14.9 1.8 1.4 9.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX92270.1 - 0.03 13.9 6.8 0.95 9.1 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX92270.1 - 0.036 13.8 1.1 3.4 7.6 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 KFX92270.1 - 0.073 12.2 3.5 0.27 10.3 2.5 1.8 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 KFX92270.1 - 0.094 13.4 0.1 0.094 13.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX92270.1 - 0.13 12.9 10.1 1.1 10.0 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFX92270.1 - 5.1 7.1 7.5 1.6 8.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 KFX92274.1 - 7.8e-28 97.4 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX92274.1 - 3.3e-19 68.7 0.0 8.2e-19 67.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFX92274.1 - 0.00088 18.5 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX92274.1 - 0.0015 18.3 0.2 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KFX92274.1 - 0.046 13.4 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KFX92276.1 - 4.1e-20 72.3 0.1 5.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX92276.1 - 1.3e-07 31.7 0.3 1.7e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX92276.1 - 0.039 12.6 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) SUR7 PF06687.7 KFX92290.1 - 1.6e-28 99.7 13.2 2e-28 99.4 9.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.8 KFX92290.1 - 0.0063 15.6 2.7 0.0098 14.9 1.9 1.2 1 0 0 1 1 1 1 CobD/Cbib protein NfeD PF01957.13 KFX92290.1 - 0.026 14.6 1.9 0.026 14.6 1.3 2.5 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4231 PF14015.1 KFX92290.1 - 0.67 9.9 9.0 0.055 13.4 2.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Bromodomain PF00439.20 KFX92303.1 - 4e-36 122.7 4.6 2.3e-19 69.1 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KFX92303.1 - 3.6e-15 55.7 0.9 3.6e-15 55.7 0.6 2.0 2 0 0 2 2 2 1 BAH domain HIT PF01230.18 KFX92305.1 - 2.3e-22 79.3 0.1 3.2e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFX92305.1 - 2.8e-13 50.1 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFX92305.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 KFX92305.1 - 0.12 12.4 0.2 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 CRAL_TRIO PF00650.15 KFX92306.1 - 1.8e-40 138.0 0.0 3.1e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX92306.1 - 5.6e-14 52.0 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFX92306.1 - 1.7e-08 34.4 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 KFX92307.1 - 0.0064 16.2 0.4 0.0099 15.6 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 zf-C2H2_jaz PF12171.3 KFX92308.1 - 6.7e-11 42.0 1.1 1.5e-10 40.8 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFX92308.1 - 0.00082 18.8 0.2 0.0021 17.5 0.2 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 KFX92308.1 - 0.0016 18.5 0.6 0.0024 17.9 0.4 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) CTNNB1_binding PF08347.6 KFX92308.1 - 0.029 14.6 0.8 0.036 14.3 0.5 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding zf-met PF12874.2 KFX92308.1 - 0.04 14.1 0.9 0.082 13.1 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Papo_T_antigen PF02380.10 KFX92308.1 - 0.074 12.9 0.3 0.21 11.5 0.0 1.7 1 1 1 2 2 2 0 T-antigen specific domain Aconitase PF00330.15 KFX92309.1 - 1.9e-175 583.8 0.0 4.3e-175 582.6 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFX92309.1 - 2.5e-45 153.7 0.0 4.9e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.17 KFX92310.1 - 1e-14 54.8 10.1 1e-14 54.8 7.0 2.0 2 0 0 2 2 2 1 Rhomboid family Nodulin-like PF06813.8 KFX92310.1 - 0.014 14.6 1.4 0.043 13.0 0.4 2.0 1 1 1 2 2 2 0 Nodulin-like Gaa1 PF04114.9 KFX92311.1 - 5.7e-102 342.0 7.1 1.1e-101 341.0 4.9 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 KFX92312.1 - 8.2e-09 35.7 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain N6-adenineMlase PF10237.4 KFX92313.1 - 3e-54 183.0 0.1 9.1e-54 181.4 0.0 1.8 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NAD_binding_10 PF13460.1 KFX92313.1 - 1.1e-18 67.8 0.0 2.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX92313.1 - 4.6e-17 62.0 0.0 6.9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFX92313.1 - 4.8e-15 55.6 0.1 9.1e-15 54.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX92313.1 - 4.3e-11 42.0 0.0 9.1e-11 40.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFX92313.1 - 5.2e-09 35.4 0.0 8.9e-08 31.3 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFX92313.1 - 8.4e-06 24.8 0.8 0.00071 18.5 0.6 3.0 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KFX92313.1 - 0.00024 20.2 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KFX92313.1 - 0.0028 17.6 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX92313.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 KFX92313.1 - 0.032 13.8 0.0 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 KR domain DDE_Tnp_1_3 PF13612.1 KFX92313.1 - 0.078 12.7 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain UCH PF00443.24 KFX92314.1 - 7.4e-32 110.5 5.1 3.2e-24 85.4 1.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX92314.1 - 1.9e-13 50.5 10.5 3.8e-12 46.2 7.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFX92314.1 - 0.00046 20.2 0.1 0.00046 20.2 0.0 2.9 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Lactamase_B PF00753.22 KFX92315.1 - 3.2e-19 69.3 1.1 5e-19 68.7 0.8 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX92315.1 - 0.00021 20.9 0.1 0.00028 20.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFX92315.1 - 0.023 14.4 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain I-set PF07679.11 KFX92316.1 - 0.00012 21.8 0.1 2.4 8.0 0.0 4.7 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.6 KFX92316.1 - 0.013 14.8 0.4 1.7 8.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 KFX92317.1 - 4e-50 169.9 0.0 5e-48 163.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 YccV-like PF08755.6 KFX92318.1 - 8.2e-24 83.4 0.2 1.6e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KFX92318.1 - 3.2e-16 59.1 0.0 6.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KFX92318.1 - 4.4e-09 35.9 0.4 1.2e-08 34.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX92318.1 - 9.8e-05 21.9 0.0 0.00023 20.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KFX92318.1 - 0.00068 19.9 0.7 0.0017 18.7 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SPX PF03105.14 KFX92319.1 - 1.5e-43 149.5 0.2 1.5e-43 149.5 0.1 1.5 2 0 0 2 2 2 1 SPX domain zf-C3HC4_3 PF13920.1 KFX92319.1 - 4.3e-07 29.4 8.3 6.8e-07 28.8 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX92319.1 - 5.1e-07 29.4 11.5 5.1e-07 29.4 8.0 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFX92319.1 - 1.4e-06 27.8 12.7 2.7e-06 26.9 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX92319.1 - 2.7e-06 27.1 10.9 5e-06 26.2 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFX92319.1 - 5.4e-06 26.0 10.0 1e-05 25.1 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX92319.1 - 3.1e-05 23.9 12.9 5.8e-05 23.0 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX92319.1 - 0.0065 16.1 8.2 0.023 14.4 5.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFX92319.1 - 0.014 14.9 4.2 0.014 14.9 2.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 KFX92319.1 - 0.028 14.3 1.2 0.048 13.6 0.8 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.2 KFX92319.1 - 0.035 14.2 3.8 0.068 13.2 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFX92319.1 - 0.1 12.4 2.6 0.19 11.5 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.7 KFX92319.1 - 0.13 12.1 3.4 0.94 9.3 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_6 PF14835.1 KFX92319.1 - 0.71 9.7 7.0 1 9.1 4.0 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 KFX92319.1 - 6 6.4 8.7 1.1e+02 2.3 6.3 2.2 1 1 1 2 2 2 0 P-11 zinc finger DnaJ PF00226.26 KFX92320.1 - 1.8e-25 88.4 0.4 4.5e-25 87.1 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KFX92320.1 - 4.5e-09 36.1 3.0 4.5e-09 36.1 2.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFX92320.1 - 4.1e-08 33.2 3.2 0.0014 18.6 0.5 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFX92320.1 - 8.1e-07 29.0 2.7 8.1e-07 29.0 1.9 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFX92320.1 - 0.0016 18.6 5.8 0.31 11.4 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.1 KFX92320.1 - 0.0023 17.2 0.1 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 A repeated domain in UCH-protein zf-C2H2_6 PF13912.1 KFX92320.1 - 0.016 15.0 3.8 0.54 10.2 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4451 PF14616.1 KFX92320.1 - 0.43 10.3 4.4 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) DUF2387 PF09526.5 KFX92320.1 - 0.64 9.9 5.5 0.31 10.9 1.2 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C2H2_4 PF13894.1 KFX92320.1 - 0.98 9.8 3.4 23 5.6 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PSCyt3 PF07627.6 KFX92320.1 - 2.1 8.2 5.6 0.78 9.6 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) Peptidase_C54 PF03416.14 KFX92321.1 - 1.1e-90 303.6 0.0 1.3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 KFX92322.1 - 8.2e-11 41.5 2.1 9.8e-11 41.2 0.4 2.0 2 0 0 2 2 2 1 G-patch domain R3H PF01424.17 KFX92322.1 - 1.5e-10 40.6 0.0 4.8e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 KFX92322.1 - 0.0022 17.8 3.1 0.0028 17.4 0.2 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site Histone PF00125.19 KFX92323.1 - 2.2e-22 78.9 0.2 3.1e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFX92323.1 - 9.9e-05 22.3 0.0 9.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFX92323.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KFX92323.1 - 0.0062 15.2 2.2 0.008 14.8 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KFX92323.1 - 0.0093 15.4 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF1018 PF06252.7 KFX92323.1 - 0.023 15.1 0.7 0.033 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 KFX92324.1 - 8.2e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFX92324.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 KFX92325.1 - 4.3e-09 36.0 1.2 6.2e-09 35.5 0.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX92325.1 - 6.5e-06 26.2 0.9 9.5e-06 25.7 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 KFX92326.1 - 7.2e-78 261.0 0.0 1e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFX92326.1 - 6e-17 61.0 1.3 1.1e-16 60.2 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KFX92326.1 - 4.6e-05 22.7 2.0 0.00051 19.2 0.3 2.3 1 1 1 2 2 2 1 HlyD family secretion protein Ndc1_Nup PF09531.5 KFX92326.1 - 3 6.1 5.3 3.9 5.7 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2413 PF10310.4 KFX92326.1 - 5.5 5.6 12.5 7.5 5.2 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CDP-OH_P_transf PF01066.16 KFX92332.1 - 5.9e-12 45.7 1.7 1.1e-11 44.9 1.2 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OTU PF02338.14 KFX92332.1 - 1.6e-10 41.6 0.0 2.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFX92332.1 - 0.00053 19.4 0.3 0.0023 17.3 0.0 1.9 1 1 1 2 2 2 1 Peptidase C65 Otubain DUF4345 PF14248.1 KFX92332.1 - 0.49 9.8 4.0 0.94 8.9 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) EI24 PF07264.6 KFX92333.1 - 3.6e-07 29.8 14.0 5.2e-05 22.7 9.8 2.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 KFX92334.1 - 5.5e-31 107.1 0.0 1.4e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Mog1 PF04603.7 KFX92335.1 - 1.1e-20 74.0 0.0 1.5e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.4 KFX92336.1 - 2e-51 173.7 0.6 2.9e-51 173.2 0.4 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 KFX92336.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Glyco_hydro_72 PF03198.9 KFX92337.1 - 4.1e-133 443.2 3.3 5.5e-133 442.7 2.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KFX92337.1 - 1.4e-26 92.7 7.3 1.4e-26 92.7 5.1 2.4 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.10 KFX92338.1 - 0 1468.1 0.0 0 1467.5 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KFX92338.1 - 2.2e-39 134.0 0.4 5e-39 132.8 0.3 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF2695 PF10905.3 KFX92339.1 - 0.042 13.5 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) DUF3276 PF11680.3 KFX92339.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Aminotran_1_2 PF00155.16 KFX92340.1 - 4.7e-35 121.2 0.0 7.2e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFX92340.1 - 0.023 12.9 0.0 0.04 12.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Zip PF02535.17 KFX92347.1 - 3e-08 33.0 0.8 3e-08 33.0 0.5 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter SieB PF14163.1 KFX92347.1 - 0.00089 18.8 0.3 0.35 10.4 0.0 2.5 2 0 0 2 2 2 2 Superinfection exclusion protein B LGT PF01790.13 KFX92347.1 - 0.046 12.6 0.3 0.16 10.8 0.1 1.8 2 0 0 2 2 2 0 Prolipoprotein diacylglyceryl transferase TauE PF01925.14 KFX92347.1 - 0.058 12.8 0.1 0.058 12.8 0.1 1.6 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE ATP-synt_8 PF00895.15 KFX92347.1 - 2.6 8.3 5.7 11 6.2 0.0 3.1 2 1 1 3 3 3 0 ATP synthase protein 8 MFS_1 PF07690.11 KFX92347.1 - 6.9 5.2 9.8 2.5 6.7 3.8 2.2 2 1 0 2 2 2 0 Major Facilitator Superfamily Menin PF05053.8 KFX92354.1 - 3.8 5.5 5.7 5.1 5.1 3.9 1.1 1 0 0 1 1 1 0 Menin Plus-3 PF03126.13 KFX92359.1 - 6.7e-29 100.1 0.0 1.5e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain HMG_box PF00505.14 KFX92362.1 - 2.5e-07 30.8 0.0 8.7e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX92362.1 - 0.0014 18.9 0.0 0.0051 17.1 0.0 2.0 1 0 0 1 1 1 1 HMG-box domain DHDPS PF00701.17 KFX92373.1 - 4.8e-29 100.8 0.1 5.9e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family RNA_pol PF00940.14 KFX92375.1 - 2.1e-156 520.4 0.0 3.3e-156 519.8 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KFX92375.1 - 5.3e-80 269.0 3.4 1e-79 268.1 2.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Oligomerisation PF02410.10 KFX92376.1 - 7.7e-07 29.0 0.3 0.015 15.3 0.1 2.6 3 0 0 3 3 3 2 Oligomerisation domain Acetyltransf_1 PF00583.19 KFX92377.1 - 2.5e-20 72.3 0.0 3.3e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX92377.1 - 9.4e-12 45.0 0.0 1.2e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX92377.1 - 7.4e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX92377.1 - 6.3e-08 32.8 0.0 8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX92377.1 - 7.2e-07 28.8 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFX92377.1 - 9.8e-07 28.7 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX92377.1 - 1.5e-06 28.2 0.0 1.9e-06 27.9 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX92377.1 - 3.7e-05 23.5 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KFX92377.1 - 0.0026 17.6 0.0 0.014 15.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3636 PF12331.3 KFX92378.1 - 1e-42 145.2 0.0 2.3e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) CTP_transf_1 PF01148.15 KFX92379.1 - 2.5e-82 276.4 29.9 3.1e-82 276.1 20.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 KFX92380.1 - 6e-74 248.3 1.1 9.4e-74 247.7 0.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX92380.1 - 4e-40 136.0 0.2 9.1e-40 134.9 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFX92380.1 - 0.00069 19.2 0.8 0.08 12.6 0.2 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KFX92380.1 - 0.0084 16.0 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Sulfate_transp PF00916.15 KFX92381.1 - 6.6e-55 186.0 0.2 1.5e-54 184.9 0.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFX92381.1 - 2e-29 101.1 5.1 6.7e-29 99.3 3.5 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFX92381.1 - 9.8e-15 54.0 0.0 1.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KFX92381.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.8 1 1 0 1 1 1 0 STAS domain Keratin_assoc PF09775.4 KFX92381.1 - 0.76 9.3 6.0 0.081 12.4 0.4 2.0 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Adaptin_N PF01602.15 KFX92382.1 - 3.7e-137 457.8 7.8 4.6e-137 457.5 5.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFX92382.1 - 8.5e-17 61.5 3.0 1.3e-16 60.9 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFX92382.1 - 1.3e-16 60.6 3.2 4.4e-10 39.6 0.0 4.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 KFX92382.1 - 1.5e-12 46.4 1.4 0.00012 21.8 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFX92382.1 - 3.1e-06 27.4 5.7 0.45 11.0 0.0 6.2 4 2 2 6 6 6 2 HEAT-like repeat Arm PF00514.18 KFX92382.1 - 1.5e-05 24.6 0.1 3.7 7.5 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KFX92382.1 - 0.00012 21.6 0.2 0.34 10.6 0.0 4.5 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KFX92382.1 - 0.00093 18.6 2.1 1.2 8.4 0.1 3.3 3 0 0 3 3 3 2 CLASP N terminal T_hemolysin PF12261.3 KFX92382.1 - 0.12 11.9 0.1 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Thermostable hemolysin DUF1077 PF06417.7 KFX92383.1 - 1.9e-51 172.6 0.8 2.3e-51 172.3 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ADH_zinc_N PF00107.21 KFX92384.1 - 2e-22 79.1 0.3 3e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX92384.1 - 1.7e-08 35.4 0.0 3.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX92384.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFX92384.1 - 0.11 12.0 1.4 0.15 11.5 0.3 1.6 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GYF PF02213.11 KFX92385.1 - 8.5e-17 60.4 0.1 1.7e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 GYF domain Zip PF02535.17 KFX92386.1 - 1 8.2 7.0 1.2 8.0 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Amidase PF01425.16 KFX92388.1 - 2.1e-63 214.7 2.4 2.4e-63 214.5 1.7 1.0 1 0 0 1 1 1 1 Amidase Lentivirus_VIF PF05851.6 KFX92388.1 - 6.7e-05 21.6 0.0 8.4e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Lentivirus virion infectivity factor (VIF) RRM_1 PF00076.17 KFX92393.1 - 1.2e-07 31.2 0.0 1.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX92393.1 - 8.4e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX92393.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp PF00026.18 KFX92396.1 - 2e-104 349.3 0.2 2.6e-104 348.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX92396.1 - 4.9e-12 46.1 0.0 9.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Clp1 PF06807.9 KFX92396.1 - 1.1e-10 41.6 0.0 2.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 TAXi_C PF14541.1 KFX92396.1 - 0.00015 21.3 0.0 0.00082 18.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFX92396.1 - 0.00042 20.7 0.1 1.1 9.7 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease AAA_10 PF12846.2 KFX92396.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 KFX92396.1 - 0.015 15.0 0.0 0.054 13.1 0.0 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFX92396.1 - 0.02 15.7 0.0 0.094 13.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX92396.1 - 0.042 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFX92396.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX92396.1 - 0.098 12.8 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Alpha-amylase_C PF02806.13 KFX92396.1 - 0.15 12.2 0.2 0.99 9.5 0.0 2.5 3 0 0 3 3 3 0 Alpha amylase, C-terminal all-beta domain FtsK_SpoIIIE PF01580.13 KFX92396.1 - 0.16 11.4 0.2 0.97 8.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2697 PF10906.3 KFX92397.1 - 2.2e-05 24.3 0.0 5.8e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2697) Y_phosphatase PF00102.22 KFX92398.1 - 1.6e-46 158.5 0.0 2.3e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFX92398.1 - 0.0017 17.9 0.0 0.0062 16.1 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFX92398.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate SMC_N PF02463.14 KFX92399.1 - 1.2e-74 250.2 13.5 3.9e-74 248.6 9.4 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX92399.1 - 5.3e-26 90.9 0.0 2.8e-25 88.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFX92399.1 - 1.1e-11 45.2 8.9 3.1e-05 24.0 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFX92399.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 KFX92399.1 - 0.00027 20.8 13.1 0.00027 20.8 9.1 7.7 4 3 4 8 8 8 2 Tropomyosin like IncA PF04156.9 KFX92399.1 - 0.00053 19.6 8.6 0.00053 19.6 5.9 8.1 2 2 7 9 9 9 5 IncA protein Reo_sigmaC PF04582.7 KFX92399.1 - 0.0013 18.0 29.8 0.0022 17.2 3.5 4.9 2 2 2 4 4 4 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFX92399.1 - 0.0014 17.1 101.0 0.0054 15.2 21.9 5.8 3 2 2 6 6 6 3 AAA domain DivIC PF04977.10 KFX92399.1 - 0.0077 15.6 0.6 0.0077 15.6 0.4 10.5 8 5 4 12 12 12 2 Septum formation initiator Fib_alpha PF08702.5 KFX92399.1 - 0.0092 16.1 6.7 0.0092 16.1 4.6 7.4 3 2 3 8 8 8 2 Fibrinogen alpha/beta chain family ELYS PF13934.1 KFX92400.1 - 1.3e-62 211.4 0.2 1.6e-62 211.1 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly zf-CCCH PF00642.19 KFX92401.1 - 0.00018 21.1 1.3 0.00033 20.2 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFX92401.1 - 0.58 10.2 4.4 1.3 9.1 3.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S10 PF00338.17 KFX92402.1 - 5.7e-30 103.0 0.5 6.8e-30 102.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 KFX92403.1 - 8.1e-11 41.1 0.3 1.9e-10 40.0 0.2 1.6 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.7 KFX92403.1 - 1.1 8.4 2.9 2 7.6 2.0 1.3 1 0 0 1 1 1 0 NOA36 protein Glyco_hydro_18 PF00704.23 KFX92405.1 - 1.7e-96 323.6 0.6 1.7e-96 323.6 0.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DnaJ PF00226.26 KFX92405.1 - 8.3e-09 35.0 0.5 1.7e-08 34.0 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S27 PF01599.14 KFX92406.1 - 1.5e-27 95.1 2.1 1.5e-27 95.1 1.4 2.2 3 0 0 3 3 3 1 Ribosomal protein S27a IBR PF01485.16 KFX92406.1 - 0.045 13.6 3.4 0.041 13.7 0.7 2.2 2 1 0 2 2 2 0 IBR domain Cucumo_2B PF03263.8 KFX92406.1 - 0.12 12.6 0.7 0.15 12.3 0.5 1.3 1 0 0 1 1 1 0 Cucumovirus protein 2B Ribosomal_S26e PF01283.14 KFX92407.1 - 7.1e-51 171.2 7.5 8.5e-51 171.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 KFX92407.1 - 0.034 14.5 0.2 7.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KFX92407.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_7 PF12838.2 KFX92407.1 - 0.08 13.3 1.5 1.4 9.3 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Prenylcys_lyase PF07156.9 KFX92408.1 - 9.7e-37 126.7 0.0 1.6e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KFX92408.1 - 1.1e-12 47.8 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KFX92408.1 - 1.6e-11 43.9 0.0 4.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KFX92408.1 - 3.5e-09 36.0 0.0 7.3e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX92408.1 - 2.4e-05 24.1 0.1 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX92408.1 - 0.0011 19.1 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX92408.1 - 0.0028 16.7 0.1 0.0054 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFX92408.1 - 0.0059 16.4 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX92408.1 - 0.0076 16.6 0.1 0.16 12.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX92408.1 - 0.019 14.3 0.1 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.10 KFX92408.1 - 0.023 14.2 0.1 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 KFX92408.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cpn60_TCP1 PF00118.19 KFX92409.1 - 1.2e-144 482.5 0.1 1.3e-144 482.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ECH PF00378.15 KFX92410.1 - 1.2e-47 162.0 0.6 2.8e-44 151.0 0.2 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Ank_2 PF12796.2 KFX92411.1 - 6.2e-19 68.1 0.1 8.6e-19 67.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92411.1 - 7.1e-19 66.5 0.4 4.6e-11 41.9 0.3 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFX92411.1 - 2.1e-16 59.9 0.4 1.7e-07 31.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX92411.1 - 4.2e-16 58.5 2.6 2.9e-09 36.8 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92411.1 - 1.1e-13 49.8 0.0 3.5e-07 29.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Apc1 PF12859.2 KFX92412.1 - 1.3e-27 96.1 0.1 4.9e-27 94.2 0.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KFX92412.1 - 0.0025 17.9 1.9 10 6.5 0.1 4.2 4 0 0 4 4 4 1 Proteasome/cyclosome repeat Borrelia_P83 PF05262.6 KFX92412.1 - 6.2 4.9 5.2 9.4 4.3 3.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF155 PF02582.9 KFX92413.1 - 4.3e-40 137.4 0.0 6.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.17 KFX92413.1 - 0.044 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin Glyco_transf_92 PF01697.22 KFX92415.1 - 3.7e-08 33.0 0.1 6.3e-08 32.2 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 KFX92415.1 - 4.6e-08 33.2 0.1 7.5e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 LANC_like PF05147.8 KFX92416.1 - 4.6e-19 68.1 0.0 2.7e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein FAD_binding_4 PF01565.18 KFX92416.1 - 5.8e-18 64.7 3.0 1.1e-17 63.8 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX92416.1 - 1.8e-09 37.3 0.4 4.4e-09 36.1 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.19 KFX92417.1 - 3.8e-08 33.2 0.4 8.6e-08 32.1 0.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX92417.1 - 6.2e-06 26.2 0.0 2.7e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX92417.1 - 2.6e-05 24.2 0.4 8.1e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX92417.1 - 0.0021 17.7 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFX92417.1 - 0.0066 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 KFX92418.1 - 4e-28 98.8 2.4 4e-28 98.8 1.6 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX92418.1 - 5.2e-10 39.2 0.0 1.3e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Histone PF00125.19 KFX92418.1 - 2.8e-05 24.1 0.9 5.5e-05 23.2 0.7 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Abhydrolase_1 PF00561.15 KFX92418.1 - 0.00036 20.1 0.1 0.0016 18.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 KFX92418.1 - 0.025 13.7 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.11 KFX92418.1 - 0.14 11.5 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_M28 PF04389.12 KFX92419.1 - 6.6e-31 107.4 0.1 2.2e-30 105.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 KFX92419.1 - 2.4e-14 52.8 0.4 2.4e-14 52.8 0.3 2.0 2 0 0 2 2 2 1 PA domain ketoacyl-synt PF00109.21 KFX92420.1 - 3e-75 252.9 0.0 6.4e-75 251.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX92420.1 - 7.7e-46 156.8 0.0 4.4e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFX92420.1 - 8.6e-33 112.7 0.5 2.2e-32 111.3 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KFX92420.1 - 3.8e-19 69.8 0.0 1.1e-18 68.3 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 KFX92420.1 - 3.3e-18 65.8 0.0 6.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase FAD_binding_3 PF01494.14 KFX92420.1 - 3.5e-15 55.9 1.5 3.8e-14 52.5 1.0 2.1 1 1 0 1 1 1 1 FAD binding domain PP-binding PF00550.20 KFX92420.1 - 1.5e-13 50.7 1.2 4.8e-13 49.1 0.8 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KFX92420.1 - 1e-06 28.8 0.6 2.5e-05 24.3 0.1 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX92420.1 - 5.7e-05 22.8 0.0 0.32 10.7 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KFX92420.1 - 0.00042 19.3 0.0 0.00088 18.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_8 PF13450.1 KFX92420.1 - 0.0066 16.4 0.1 0.06 13.3 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KFX92420.1 - 0.14 10.9 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DUF2974 PF11187.3 KFX92420.1 - 0.32 10.3 0.0 0.64 9.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) EthD PF07110.6 KFX92421.1 - 2.1e-19 70.2 0.0 2.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 KFX92422.1 - 1.1e-37 129.6 57.8 1.5e-37 129.1 35.6 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily HypD PF01924.11 KFX92422.1 - 0.046 12.4 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF1295 PF06966.7 KFX92423.1 - 1.1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KFX92423.1 - 5.5e-06 25.1 0.1 8.6e-06 24.5 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 KFX92423.1 - 6.9e-05 22.9 0.5 0.00074 19.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KFX92423.1 - 0.00051 19.8 0.1 0.00088 19.0 0.0 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase NnrU PF07298.6 KFX92423.1 - 0.00057 19.3 0.1 0.00086 18.7 0.1 1.2 1 0 0 1 1 1 1 NnrU protein ICMT PF04140.9 KFX92423.1 - 0.0033 17.6 0.0 0.0083 16.2 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PBP1_TM PF14812.1 KFX92427.1 - 0.12 12.6 1.0 0.21 11.9 0.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.4 KFX92427.1 - 0.21 9.8 14.6 0.23 9.6 10.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMF_DNA_bd PF12329.3 KFX92430.1 - 0.011 15.4 2.9 0.037 13.8 2.0 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zinc_ribbon_2 PF13240.1 KFX92430.1 - 0.12 11.9 0.3 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain IFT20 PF14931.1 KFX92430.1 - 1.6 8.6 8.0 0.61 9.9 2.8 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 3-dmu-9_3-mt PF06983.8 KFX92431.1 - 3.8e-45 152.9 0.2 5.3e-45 152.4 0.1 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.20 KFX92431.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NmrA PF05368.8 KFX92432.1 - 9.6e-32 110.0 0.0 1.2e-30 106.5 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX92432.1 - 9.3e-08 32.2 0.1 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX92432.1 - 0.00012 20.9 0.0 0.00017 20.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFX92432.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KFX92432.1 - 0.0015 17.9 0.0 0.0039 16.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFX92432.1 - 0.0016 18.4 0.2 0.0025 17.7 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KFX92432.1 - 0.017 15.4 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KFX92432.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF3425 PF11905.3 KFX92433.1 - 1e-22 80.5 0.5 2.2e-22 79.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX92433.1 - 0.018 14.9 4.7 0.031 14.2 3.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor CrtC PF07143.6 KFX92434.1 - 1.5e-16 60.6 0.7 3.7e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) AMP-binding_C PF13193.1 KFX92457.1 - 3.1e-15 56.8 0.0 2.2e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Zip PF02535.17 KFX92473.1 - 1.5e-27 96.4 8.1 1.7e-27 96.2 5.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.15 KFX92474.1 - 8.5e-116 385.8 0.8 1e-115 385.5 0.5 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFX92474.1 - 1.9e-05 23.7 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 KFX92475.1 - 1.1e-53 177.3 18.1 2.3e-10 39.9 0.2 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 KFX92475.1 - 2.6e-11 43.0 0.3 5.2e-11 42.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KFX92475.1 - 5.3e-09 34.7 8.7 0.007 14.5 0.5 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KFX92475.1 - 9.8e-06 25.0 0.6 2.1e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KFX92475.1 - 0.00043 19.8 5.4 0.035 13.5 0.3 3.1 3 1 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 KFX92475.1 - 0.00072 19.7 0.3 6.4 7.2 0.0 5.3 5 1 0 5 5 5 1 PQQ-like domain Nucleoporin_N PF08801.6 KFX92475.1 - 0.0017 17.1 0.3 0.25 10.0 0.0 3.1 1 1 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.1 KFX92475.1 - 0.022 14.5 0.2 2.8 7.7 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region A2L_zn_ribbon PF08792.5 KFX92480.1 - 0.093 12.2 0.2 0.093 12.2 0.1 6.4 6 3 2 8 8 8 0 A2L zinc ribbon domain Ribosomal_60s PF00428.14 KFX92480.1 - 0.25 11.7 8.8 0.88 10.0 6.1 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein GCD14 PF08704.5 KFX92485.1 - 0.013 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RRM_1 PF00076.17 KFX92486.1 - 5.2e-44 147.7 0.0 8.2e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX92486.1 - 1.5e-24 85.7 0.0 2e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX92486.1 - 1.1e-20 73.2 0.0 2.7e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX92486.1 - 5.4e-06 26.2 0.0 0.0001 22.1 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFX92486.1 - 8.9e-05 22.1 0.0 0.0088 15.7 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif FAD_binding_4 PF01565.18 KFX92489.1 - 1.1e-12 47.6 0.4 2.3e-12 46.5 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX92489.1 - 1.4e-08 34.5 0.1 2.6e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like 2OG-FeII_Oxy PF03171.15 KFX92490.1 - 5.1e-11 42.7 0.0 8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFX92490.1 - 0.004 17.6 0.0 0.0069 16.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Haem_oxygenas_2 PF14518.1 KFX92491.1 - 4.1e-11 42.9 0.1 1e-10 41.7 0.0 1.7 1 0 0 1 1 1 1 Iron-containing redox enzyme Acetyltransf_1 PF00583.19 KFX92492.1 - 5.3e-11 42.3 0.0 9.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFX92492.1 - 1.4e-06 28.2 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX92492.1 - 9.6e-06 25.7 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX92492.1 - 2e-05 24.5 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX92492.1 - 0.00034 20.7 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX92492.1 - 0.0042 16.7 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KFX92492.1 - 0.034 14.0 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KFX92492.1 - 0.049 13.7 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Trp_DMAT PF11991.3 KFX92493.1 - 1.7e-63 215.0 0.0 2.2e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Vps16_N PF04841.8 KFX92493.1 - 0.089 11.2 0.1 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region AMP-binding PF00501.23 KFX92494.1 - 7.5e-48 162.9 0.0 9.9e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX92494.1 - 0.00047 21.0 0.0 0.0014 19.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF290 PF01060.18 KFX92494.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family Cupin_2 PF07883.6 KFX92495.1 - 8.3e-06 25.2 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain COesterase PF00135.23 KFX92496.1 - 1.9e-75 254.5 0.0 1.1e-59 202.5 0.0 3.0 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX92496.1 - 0.0034 16.9 0.1 0.0075 15.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.10 KFX92497.1 - 1.3e-29 102.3 3.0 4.7e-29 100.5 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KFX92497.1 - 6.7e-27 94.3 0.0 5.2e-26 91.4 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX92497.1 - 7.4e-22 77.3 5.5 1.8e-18 66.3 0.3 3.4 2 1 0 2 2 2 2 Multicopper oxidase PhzC-PhzF PF02567.11 KFX92498.1 - 1.8e-15 56.8 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Cyclin PF08613.6 KFX92499.1 - 3e-16 60.1 0.0 4.8e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX92499.1 - 0.0037 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-DHHC PF01529.15 KFX92500.1 - 6.2e-43 146.2 5.3 9e-43 145.6 3.7 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFX92500.1 - 0.031 14.0 0.9 0.084 12.6 0.4 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily DZR PF12773.2 KFX92500.1 - 0.065 13.0 6.3 0.15 11.8 4.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.1 KFX92501.1 - 2.2e-05 24.1 1.0 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX92501.1 - 0.0068 16.6 1.7 4.1 7.9 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type SpoVR PF04293.8 KFX92501.1 - 0.01 14.2 0.1 0.015 13.6 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein zf-met PF12874.2 KFX92501.1 - 0.014 15.5 3.9 2.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFX92501.1 - 0.19 11.8 3.2 1.4 9.0 1.8 2.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TIP120 PF08623.5 KFX92502.1 - 3.5e-63 212.2 0.8 1.3e-61 207.1 0.1 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KFX92502.1 - 1.2e-12 47.9 22.3 0.11 12.8 0.0 9.7 9 2 1 11 11 10 5 HEAT repeats HEAT PF02985.17 KFX92502.1 - 6.1e-11 41.4 13.9 0.55 10.4 0.0 10.9 11 0 0 11 11 11 2 HEAT repeat DUF2435 PF10363.4 KFX92502.1 - 4.3e-05 23.3 10.6 1 9.2 0.0 6.7 6 1 1 7 7 6 2 Protein of unknown function (DUF2435) Proteasom_PSMB PF10508.4 KFX92502.1 - 9.8e-05 20.8 0.4 0.16 10.2 0.0 3.5 3 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KFX92502.1 - 0.00015 21.6 8.7 0.17 11.6 0.0 5.5 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KFX92502.1 - 0.00027 21.2 1.6 2.8 8.3 0.0 6.3 6 3 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 KFX92502.1 - 0.025 14.0 4.8 0.035 13.5 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3554) VHS PF00790.14 KFX92502.1 - 0.071 12.7 0.0 19 4.8 0.0 4.2 4 0 0 4 4 4 0 VHS domain MIF4G PF02854.14 KFX92502.1 - 0.24 10.7 1.1 0.88 8.9 0.1 2.4 3 0 0 3 3 3 0 MIF4G domain DUF2457 PF10446.4 KFX92502.1 - 0.42 9.2 6.2 0.63 8.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HEAT_EZ PF13513.1 KFX92502.1 - 1.3 9.5 36.0 7.7 7.1 0.0 12.2 11 4 3 14 14 14 0 HEAT-like repeat Ycf1 PF05758.7 KFX92503.1 - 0.0016 16.2 7.4 0.0016 16.2 5.1 1.1 1 0 0 1 1 1 1 Ycf1 Hid1 PF12722.2 KFX92503.1 - 0.095 10.3 10.6 0.1 10.2 7.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Coiled PF05710.7 KFX92503.1 - 0.13 12.7 0.7 0.27 11.7 0.5 1.5 1 0 0 1 1 1 0 Coiled coil FAM60A PF15396.1 KFX92503.1 - 0.23 11.1 12.3 0.38 10.4 8.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF2215 PF10225.4 KFX92503.1 - 0.69 9.3 3.2 1.2 8.4 2.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Caldesmon PF02029.10 KFX92503.1 - 1.5 7.1 39.4 2 6.7 27.3 1.2 1 0 0 1 1 1 0 Caldesmon MIP-T3 PF10243.4 KFX92503.1 - 4.5 5.6 51.9 5.4 5.3 36.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLAC8 PF04749.12 KFX92504.1 - 2.7e-15 56.8 9.4 5e-15 55.9 6.5 1.4 1 0 0 1 1 1 1 PLAC8 family 7TM_GPCR_Srd PF10317.4 KFX92504.1 - 0.71 8.8 0.4 1 8.3 0.3 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Ras PF00071.17 KFX92505.1 - 3e-31 107.9 0.1 4e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX92505.1 - 2.5e-20 73.1 0.1 8.6e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFX92505.1 - 1.4e-06 27.6 0.1 1.9e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX92505.1 - 1.5e-05 24.2 0.2 2.1e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 KFX92505.1 - 0.019 13.6 0.2 3.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 KFX92505.1 - 0.21 10.2 0.0 0.21 10.2 0.0 2.4 1 1 2 3 3 3 0 G-protein alpha subunit DUF605 PF04652.11 KFX92505.1 - 9.1 5.5 13.8 13 5.0 9.6 1.2 1 0 0 1 1 1 0 Vta1 like GCV_H PF01597.14 KFX92506.1 - 7.8e-33 112.7 0.3 9.2e-33 112.5 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein PSI_PsaE PF02427.12 KFX92506.1 - 0.13 11.6 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Porphobil_deam PF01379.15 KFX92507.1 - 3.1e-80 268.1 0.0 4.1e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KFX92507.1 - 6.6e-19 67.7 0.2 1.3e-18 66.8 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Methyltransf_23 PF13489.1 KFX92508.1 - 2.6e-22 79.2 0.0 3.7e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX92508.1 - 8.6e-10 38.9 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX92508.1 - 2.3e-08 33.7 0.0 4.3e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92508.1 - 4.2e-07 30.5 0.0 7.8e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX92508.1 - 2e-06 28.1 0.0 3.5e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX92508.1 - 0.00014 22.1 0.0 0.00049 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX92508.1 - 0.00074 18.6 0.0 0.0068 15.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KFX92508.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KFX92508.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1996 PF09362.5 KFX92509.1 - 6.4e-83 278.0 2.4 8.3e-83 277.6 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 KFX92509.1 - 7.1e-13 47.9 10.7 7.1e-13 47.9 7.4 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX92509.1 - 0.00094 19.1 2.1 0.0026 17.7 1.5 1.8 1 0 0 1 1 1 1 Toxin 7 WD40 PF00400.27 KFX92513.1 - 4.1e-10 39.1 0.1 0.0013 18.5 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Prp19 PF08606.6 KFX92513.1 - 0.0011 18.7 0.2 0.0025 17.4 0.2 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like Coatomer_WDAD PF04053.9 KFX92513.1 - 0.0016 17.2 0.0 0.048 12.4 0.0 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Chs3p PF12271.3 KFX92514.1 - 2.2e-140 466.7 14.9 2.5e-140 466.5 10.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KFX92514.1 - 5.3 7.0 10.5 0.9 9.4 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) NTP_transferase PF00483.18 KFX92517.1 - 5.3e-29 101.2 0.0 6.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KFX92517.1 - 3.5e-10 38.9 6.9 2.5e-06 26.7 0.1 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFX92517.1 - 1e-06 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KFX92517.1 - 0.026 14.0 3.1 0.085 12.4 0.0 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 KFX92517.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Dynamin_N PF00350.18 KFX92518.1 - 2.9e-20 72.7 0.0 3.4e-19 69.2 0.0 2.6 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFX92518.1 - 1.7e-14 53.2 1.6 3.9e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KFX92518.1 - 9.2e-07 28.6 0.5 3.9e-06 26.6 0.4 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX92518.1 - 9.4e-05 22.3 0.0 0.01 15.8 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 KFX92518.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TraQ PF09679.5 KFX92519.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) APH PF01636.18 KFX92520.1 - 2e-10 40.8 0.0 2.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFX92520.1 - 2.2e-06 27.0 0.1 3.2e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFX92520.1 - 1.4e-05 24.7 0.2 3.1e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KFX92520.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 KFX92520.1 - 0.0014 17.3 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF302 PF03625.9 KFX92521.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF302 Jnk-SapK_ap_N PF09744.4 KFX92521.1 - 0.093 12.7 3.3 0.14 12.1 2.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Med3 PF11593.3 KFX92521.1 - 0.18 10.9 1.9 0.24 10.5 1.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF16 PF01519.11 KFX92521.1 - 1.7 8.9 4.4 4.4 7.5 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Rib_recp_KP_reg PF05104.7 KFX92521.1 - 8.9 6.8 13.1 0.76 10.2 1.6 2.6 1 1 1 2 2 2 0 Ribosome receptor lysine/proline rich region ASCH PF04266.9 KFX92522.1 - 0.086 13.2 0.0 0.51 10.7 0.0 2.0 1 1 0 1 1 1 0 ASCH domain HIT PF01230.18 KFX92523.1 - 1.9e-19 69.9 0.1 3.8e-19 69.0 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KFX92523.1 - 1.2e-06 28.7 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFX92523.1 - 0.0022 17.6 0.0 0.0061 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 ATG16 PF08614.6 KFX92525.1 - 0.045 13.5 7.7 0.019 14.7 2.5 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DinB PF05163.7 KFX92525.1 - 0.065 12.9 0.5 0.065 12.9 0.4 2.0 1 1 0 2 2 2 0 DinB family Syntaxin-18_N PF10496.4 KFX92525.1 - 0.098 12.5 0.5 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus FUSC PF04632.7 KFX92525.1 - 0.33 9.3 1.7 0.38 9.1 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 KFX92525.1 - 0.34 8.7 1.5 0.41 8.4 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 KFX92525.1 - 0.45 10.3 8.1 0.65 9.8 5.6 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.7 KFX92525.1 - 1.6 8.0 11.3 0.12 11.7 1.7 2.3 1 1 1 2 2 2 0 PspA/IM30 family DUF2203 PF09969.4 KFX92525.1 - 2.2 8.5 4.8 5.4 7.2 3.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Seryl_tRNA_N PF02403.17 KFX92525.1 - 7.7 6.5 8.5 1.3 9.0 1.9 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RNA_pol_Rpb4 PF03874.11 KFX92536.1 - 1e-28 99.6 1.8 1.2e-28 99.4 1.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF789 PF05623.7 KFX92536.1 - 0.0054 16.2 0.1 0.0062 16.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF789) Sybindin PF04099.7 KFX92537.1 - 3e-51 172.8 0.0 3.8e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KFX92537.1 - 1.6e-09 37.6 0.1 2.9e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4375 PF14300.1 KFX92537.1 - 0.086 12.8 0.1 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) VWA_2 PF13519.1 KFX92538.1 - 4.7e-14 52.8 0.1 6.7e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX92538.1 - 1.4e-07 31.3 0.3 2e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KFX92538.1 - 4.5e-07 29.6 0.1 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KFX92538.1 - 0.00061 19.1 1.1 0.0018 17.7 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif LRR_6 PF13516.1 KFX92544.1 - 6.2e-11 41.2 5.0 0.23 11.6 0.0 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 KFX92544.1 - 7.6e-07 28.6 9.1 0.24 11.0 0.2 5.6 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX92544.1 - 0.0026 17.5 5.4 7.2 7.0 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 KFX92544.1 - 0.74 9.6 9.1 26 4.6 0.0 4.1 4 2 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KFX92544.1 - 6.5 7.4 7.1 44 4.9 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat COX17 PF05051.8 KFX92545.1 - 2.1e-20 72.4 4.8 2.4e-20 72.3 3.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFX92545.1 - 0.21 11.3 4.1 0.65 9.8 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sec10 PF07393.6 KFX92546.1 - 1.4e-222 740.8 3.7 2.1e-222 740.2 2.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 GAS PF13851.1 KFX92546.1 - 0.0043 16.2 0.4 0.012 14.8 0.3 1.7 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KFX92546.1 - 0.12 12.1 3.5 0.37 10.5 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prenyltransf PF01255.14 KFX92547.1 - 2e-06 27.1 0.0 0.0001 21.4 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase IBR PF01485.16 KFX92548.1 - 6.1e-13 48.4 27.6 8e-08 32.0 3.2 2.6 2 0 0 2 2 2 2 IBR domain MFS_1 PF07690.11 KFX92549.1 - 2.8e-37 128.2 58.7 6.1e-29 100.8 13.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX92549.1 - 2.8e-11 42.6 15.0 2.8e-11 42.6 10.4 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Met_10 PF02475.11 KFX92550.1 - 5.7e-64 215.3 0.0 8.4e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Glyco_transf_34 PF05637.7 KFX92550.1 - 1.7e-61 207.8 0.2 2.4e-61 207.2 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Methyltransf_18 PF12847.2 KFX92550.1 - 0.0028 18.1 0.0 0.0087 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX92550.1 - 0.0068 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HATPase_c PF02518.21 KFX92551.1 - 4.3e-29 100.4 0.0 2.1e-28 98.2 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX92551.1 - 3.6e-21 75.2 0.1 1.6e-20 73.1 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KFX92551.1 - 8.5e-20 70.5 0.2 3.2e-19 68.6 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KFX92551.1 - 3.5e-14 53.2 0.7 2e-13 50.7 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KFX92551.1 - 5.9e-09 36.5 0.0 1.7e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KFX92551.1 - 1.1e-08 34.6 0.0 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 KFX92551.1 - 2.6e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain NACHT PF05729.7 KFX92551.1 - 0.0045 16.6 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KFX92551.1 - 0.051 12.3 0.1 0.1 11.3 0.1 1.4 1 0 0 1 1 1 0 ArgK protein PTS_EIIB PF00367.15 KFX92551.1 - 0.12 11.5 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB TPR_8 PF13181.1 KFX92551.1 - 0.14 11.9 0.0 1.4 8.8 0.0 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPT PF03151.11 KFX92556.1 - 1.6e-25 89.5 8.9 1.6e-25 89.5 6.1 2.7 3 1 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 KFX92556.1 - 0.0077 16.4 1.8 0.0077 16.4 1.3 4.4 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KFX92556.1 - 0.14 12.2 25.9 0.37 10.8 4.5 4.0 3 1 0 4 4 4 0 EamA-like transporter family RskA PF10099.4 KFX92556.1 - 0.15 11.7 0.6 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA UAA PF08449.6 KFX92556.1 - 0.18 10.7 21.5 0.017 14.0 8.6 3.0 2 1 1 3 3 3 0 UAA transporter family NAD_binding_8 PF13450.1 KFX92557.1 - 1.4e-09 37.8 0.1 4.7e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX92557.1 - 3.8e-05 23.8 0.1 0.00026 21.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFX92557.1 - 5.1e-05 22.5 0.0 0.00026 20.2 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KFX92557.1 - 0.0091 15.8 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX92557.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KFX92557.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KFX92557.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 KFX92557.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding LysM PF01476.15 KFX92563.1 - 2.2e-15 56.2 7.1 2.7e-05 23.9 0.0 6.5 7 0 0 7 7 7 4 LysM domain Glyco_hydro_18 PF00704.23 KFX92564.1 - 1.1e-80 271.6 2.9 1.8e-80 270.9 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX92564.1 - 5.5e-09 35.8 12.5 5.5e-09 35.8 8.6 4.1 4 0 0 4 4 4 2 Chitin recognition protein Daxx PF03344.10 KFX92565.1 - 0.11 10.9 14.1 0.18 10.2 9.8 1.2 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 KFX92565.1 - 0.84 8.7 13.2 1.5 7.9 9.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) BUD22 PF09073.5 KFX92565.1 - 1.6 7.6 24.8 3.7 6.4 17.2 1.5 1 0 0 1 1 1 0 BUD22 DUF605 PF04652.11 KFX92565.1 - 2.3 7.5 20.3 4 6.7 14.1 1.2 1 0 0 1 1 1 0 Vta1 like TFIIF_alpha PF05793.7 KFX92565.1 - 3.6 5.8 21.0 5.8 5.1 14.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.27 KFX92566.1 - 4.9e-21 73.7 7.7 1.9e-06 27.4 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFX92566.1 - 0.0035 16.1 0.0 1.8 7.2 0.0 2.1 1 1 0 2 2 2 2 Nup133 N terminal like STE2 PF02116.10 KFX92570.1 - 3e-84 282.4 18.2 3.5e-84 282.1 12.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Vps23_core PF09454.5 KFX92572.1 - 2.6e-21 74.9 0.0 6.4e-21 73.7 0.0 1.6 2 0 0 2 2 2 1 Vps23 core domain Sugar_tr PF00083.19 KFX92574.1 - 6.8e-56 189.7 16.7 4.7e-55 186.9 11.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX92574.1 - 1.3e-08 33.6 15.4 3e-05 22.6 3.7 3.3 2 1 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 KFX92574.1 - 2.2e-05 23.3 36.6 7.2e-05 21.6 19.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4535 PF15054.1 KFX92574.1 - 0.27 10.6 1.0 0.54 9.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) CTNNBL PF08216.6 KFX92575.1 - 2.5e-36 123.5 1.3 9.7e-36 121.6 0.1 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KFX92575.1 - 0.0033 17.1 0.0 0.31 10.9 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat SpecificRecomb PF10136.4 KFX92575.1 - 0.0033 15.5 0.1 0.0055 14.8 0.0 1.3 1 0 0 1 1 1 1 Site-specific recombinase HEAT_2 PF13646.1 KFX92575.1 - 0.017 15.3 3.6 0.88 9.8 0.1 3.0 1 1 0 2 2 2 0 HEAT repeats TPR_11 PF13414.1 KFX92576.1 - 3.8e-11 42.4 0.0 1.1e-07 31.3 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFX92576.1 - 3e-07 29.8 0.0 0.078 12.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX92576.1 - 7.4e-06 25.8 0.0 0.031 14.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat LRR_4 PF12799.2 KFX92576.1 - 1.2e-05 24.8 10.3 0.067 12.8 0.4 5.9 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KFX92576.1 - 1.2e-05 24.8 0.1 2.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX92576.1 - 0.00018 21.0 0.0 0.00057 19.4 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 KFX92576.1 - 0.00065 19.1 0.0 0.77 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX92576.1 - 0.0028 18.1 0.0 9.4 7.1 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat LRR_7 PF13504.1 KFX92576.1 - 0.011 15.7 6.7 38 5.1 0.2 6.6 7 0 0 7 7 6 0 Leucine rich repeat TPR_8 PF13181.1 KFX92576.1 - 0.036 13.8 0.0 6.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.1 KFX92576.1 - 0.22 11.2 11.1 0.76 9.5 1.0 4.9 5 1 1 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KFX92576.1 - 0.29 11.3 6.0 68 4.0 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 KFX92576.1 - 3.8 7.9 8.6 1.1e+02 3.4 0.0 5.6 6 0 0 6 6 5 0 Leucine Rich Repeat DUF1996 PF09362.5 KFX92577.1 - 3.5e-91 305.0 1.0 5.2e-91 304.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MS_channel PF00924.13 KFX92580.1 - 1.7e-14 53.6 0.0 1.8e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel BLOC1_2 PF10046.4 KFX92580.1 - 0.086 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Membr_traf_MHD PF10540.4 KFX92581.1 - 4.5e-22 78.3 0.1 1.2e-21 76.8 0.1 1.8 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KFX92581.1 - 4.4e-16 58.4 2.8 1.2e-15 57.0 0.0 2.9 4 0 0 4 4 4 1 C2 domain DUF810 PF05664.6 KFX92581.1 - 3.4e-08 32.2 0.3 5.7e-08 31.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) Ins_P5_2-kin PF06090.7 KFX92584.1 - 1.2e-32 113.1 0.0 1.4e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase MFS_1 PF07690.11 KFX92591.1 - 3.9e-20 71.8 52.9 4.1e-17 61.9 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX92591.1 - 4.6e-05 22.0 36.0 0.0033 15.8 13.5 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein Fungal_trans PF04082.13 KFX92593.1 - 9.4e-39 132.8 0.3 1.6e-38 132.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92593.1 - 7.3e-05 22.5 13.6 0.00014 21.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 KFX92594.1 - 2.2e-42 144.5 1.6 1.7e-20 73.7 0.0 4.0 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 KFX92594.1 - 8.2e-19 68.6 5.3 9.2e-07 29.0 0.7 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KFX92594.1 - 2.3e-08 33.5 1.1 0.022 14.0 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX92594.1 - 3.1e-07 31.2 0.3 0.018 15.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain ABC_tran_2 PF12848.2 KFX92594.1 - 3.5e-07 29.9 2.3 3.5e-07 29.9 1.6 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KFX92594.1 - 7.9e-07 28.5 0.1 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFX92594.1 - 4.9e-06 26.4 0.0 0.057 13.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX92594.1 - 6.4e-06 26.3 0.8 0.72 9.9 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KFX92594.1 - 4.8e-05 23.6 0.4 0.26 11.6 0.5 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFX92594.1 - 5.2e-05 22.8 0.0 0.45 10.0 0.0 3.8 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 KFX92594.1 - 0.00019 21.1 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KFX92594.1 - 0.0003 20.7 2.9 0.66 9.9 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.1 KFX92594.1 - 0.0004 20.7 10.9 0.016 15.5 0.9 3.3 3 1 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX92594.1 - 0.00056 19.4 0.2 0.024 14.1 0.0 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.1 KFX92594.1 - 0.0015 17.6 0.0 0.045 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 KFX92594.1 - 0.002 18.1 7.0 0.96 9.4 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KFX92594.1 - 0.0028 17.1 0.1 2.1 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KFX92594.1 - 0.0041 16.3 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Thymidylate_kin PF02223.12 KFX92594.1 - 0.0057 16.0 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase cobW PF02492.14 KFX92594.1 - 0.008 15.6 0.3 1.5 8.2 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KFX92594.1 - 0.013 15.9 0.0 8.3 6.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein NTPase_1 PF03266.10 KFX92594.1 - 0.016 14.9 0.1 6.1 6.5 0.0 3.1 3 0 0 3 3 3 0 NTPase MobB PF03205.9 KFX92594.1 - 0.016 14.8 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 KFX92594.1 - 0.023 13.9 0.1 2 7.6 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_33 PF13671.1 KFX92594.1 - 0.026 14.3 1.4 6.2 6.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 KFX92594.1 - 0.033 14.0 8.3 0.11 12.2 0.0 3.3 4 0 0 4 4 3 0 Domain of unknown function DUF87 SRP54 PF00448.17 KFX92594.1 - 0.033 13.6 0.1 1.9 7.8 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain ArgK PF03308.11 KFX92594.1 - 0.049 12.4 1.0 0.57 8.9 0.0 2.6 3 0 0 3 3 3 0 ArgK protein AAA_25 PF13481.1 KFX92594.1 - 0.052 12.9 0.5 2 7.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 KFX92594.1 - 0.053 12.2 0.2 0.12 11.0 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.9 KFX92594.1 - 0.065 12.9 0.5 3.5 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KFX92594.1 - 0.073 12.8 1.6 14 5.4 0.1 3.2 3 1 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 KFX92594.1 - 0.12 12.5 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.1 KFX92594.1 - 0.23 9.8 4.0 4 5.7 0.0 3.1 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KFX92594.1 - 0.36 9.6 2.6 12 4.6 0.0 3.2 4 0 0 4 4 4 0 NB-ARC domain SNF2_N PF00176.18 KFX92595.1 - 1.5e-25 89.6 0.2 1.9e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KFX92595.1 - 3.8e-16 59.1 0.0 1.1e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KFX92595.1 - 0.0015 18.2 15.9 0.0021 17.7 4.9 2.6 2 0 0 2 2 2 2 zinc-RING finger domain Pyr_redox_2 PF07992.9 KFX92596.1 - 9.6e-17 61.5 0.0 1.7e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX92596.1 - 0.00014 20.5 0.0 0.015 13.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KFX92596.1 - 0.00038 20.5 0.2 0.26 11.3 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX92596.1 - 0.00082 18.3 0.8 0.78 8.5 0.0 2.2 1 1 1 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KFX92596.1 - 0.0054 16.5 0.3 0.86 9.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KFX92596.1 - 0.0055 15.6 0.5 0.42 9.4 0.1 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase DUF4132 PF13569.1 KFX92596.1 - 0.017 14.6 0.3 0.59 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4132) Rick_17kDa_Anti PF05433.10 KFX92598.1 - 0.0043 16.6 1.9 0.0071 15.9 1.3 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF1517 PF07466.6 KFX92598.1 - 0.021 13.8 1.5 0.037 13.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Podoplanin PF05808.6 KFX92598.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.1 KFX92598.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KFX92598.1 - 0.14 11.4 2.7 0.27 10.5 1.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF456 PF04306.8 KFX92598.1 - 1.1 9.3 6.0 1.6 8.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Recep_L_domain PF01030.19 KFX92599.1 - 0.00037 20.4 0.1 0.057 13.3 0.0 2.9 3 0 0 3 3 3 2 Receptor L domain SKG6 PF08693.5 KFX92599.1 - 0.035 13.4 1.5 0.072 12.4 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_12 PF13424.1 KFX92601.1 - 4.6e-49 164.2 12.6 7.2e-14 51.4 1.8 7.7 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFX92601.1 - 1.9e-36 122.9 27.1 3.6e-07 29.9 0.1 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat NB-ARC PF00931.17 KFX92601.1 - 1e-18 67.2 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 KFX92601.1 - 3.3e-18 64.5 19.0 0.018 15.6 0.3 9.9 7 2 4 11 11 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92601.1 - 4.5e-16 58.2 11.6 1.2e-07 31.2 1.3 6.4 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 KFX92601.1 - 1.2e-15 57.7 14.1 0.00045 20.8 0.9 6.4 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX92601.1 - 8e-14 51.7 9.3 0.0054 17.0 0.3 7.0 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFX92601.1 - 3.9e-11 41.9 27.3 0.0083 15.9 0.8 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat ADH_zinc_N PF00107.21 KFX92601.1 - 1e-10 41.2 0.1 3e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX92601.1 - 9e-10 38.2 0.0 3.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Apc3 PF12895.2 KFX92601.1 - 7.1e-08 32.4 6.4 0.00035 20.6 0.8 4.2 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFX92601.1 - 3.1e-07 29.6 14.6 1.8 8.5 0.2 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX92601.1 - 1.3e-06 27.7 13.7 0.07 12.7 0.5 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFX92601.1 - 6.3e-06 26.1 13.9 1 9.9 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat AAA_16 PF13191.1 KFX92601.1 - 3.2e-05 24.0 0.5 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_6 PF13174.1 KFX92601.1 - 4.5e-05 23.6 12.8 1.7 9.2 0.4 7.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX92601.1 - 6.3e-05 22.8 0.1 0.31 11.3 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX92601.1 - 0.001 18.7 14.5 0.22 11.3 0.1 6.9 8 0 0 8 8 6 1 Tetratricopeptide repeat NACHT PF05729.7 KFX92601.1 - 0.0013 18.3 0.1 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX92601.1 - 0.0018 18.4 0.0 0.0067 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_21 PF09976.4 KFX92601.1 - 0.0026 17.7 2.5 0.028 14.3 0.2 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFX92601.1 - 0.0027 17.7 7.7 0.45 10.6 0.6 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat Fungal_trans PF04082.13 KFX92602.1 - 5.7e-27 94.2 0.7 1e-26 93.4 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92602.1 - 8.9e-08 31.9 15.8 2.2e-07 30.6 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 KFX92602.1 - 1.2 9.2 7.4 29 4.8 0.0 2.7 2 0 0 2 2 2 0 Opy2 protein NAD_binding_8 PF13450.1 KFX92603.1 - 1.3e-15 57.1 0.0 4.7e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX92603.1 - 1.6e-06 27.2 0.0 4.5e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX92603.1 - 1.1e-05 24.5 0.2 0.00064 18.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX92603.1 - 0.0003 20.7 0.1 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFX92603.1 - 0.0004 19.5 0.0 0.82 8.6 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KFX92603.1 - 0.0014 18.4 0.1 0.021 14.6 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX92603.1 - 0.0014 18.9 0.2 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX92603.1 - 0.0026 16.3 0.1 0.51 8.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Mqo PF06039.10 KFX92603.1 - 0.02 13.1 0.0 0.031 12.4 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 KFX92603.1 - 0.053 13.5 0.1 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX92603.1 - 0.063 11.9 0.0 0.093 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KFX92603.1 - 0.17 10.7 0.2 0.27 10.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3742 PF12553.3 KFX92603.1 - 5.1 7.6 5.5 7.9 7.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) DLH PF01738.13 KFX92604.1 - 2.9e-29 101.8 0.0 3.4e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2497 PF10691.4 KFX92604.1 - 0.036 14.0 0.1 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) Abhydrolase_1 PF00561.15 KFX92604.1 - 0.11 12.0 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold FMO-like PF00743.14 KFX92605.1 - 2.3e-49 168.0 0.0 2.6e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX92605.1 - 7.4e-28 97.9 0.0 8.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX92605.1 - 4.4e-10 39.7 0.0 5.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX92605.1 - 1.6e-09 37.1 0.1 2.7e-09 36.3 0.0 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFX92605.1 - 1.9e-05 24.5 0.0 4.3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX92605.1 - 0.00061 18.9 0.3 0.14 11.3 0.2 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFX92605.1 - 0.0018 17.6 0.1 0.084 12.2 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Pyr_redox PF00070.22 KFX92605.1 - 0.003 17.9 3.3 0.36 11.2 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 KFX92605.1 - 0.0031 17.3 0.8 0.017 15.0 0.2 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 KFX92605.1 - 0.0049 17.0 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.19 KFX92605.1 - 0.0056 15.6 0.1 0.68 8.7 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFX92605.1 - 0.016 14.5 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 KFX92605.1 - 0.025 14.5 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 KFX92605.1 - 0.075 12.8 0.3 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 ThiF family LMWPc PF01451.16 KFX92610.1 - 1.9e-21 76.8 0.0 2.1e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Polysacc_deac_1 PF01522.16 KFX92610.1 - 0.0077 15.8 0.0 0.023 14.3 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF1470 PF07336.6 KFX92610.1 - 0.021 15.1 0.6 0.033 14.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) DUF1488 PF07369.6 KFX92610.1 - 0.062 13.1 0.3 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) CHAP PF05257.11 KFX92611.1 - 3.5e-22 78.3 7.2 7.1e-22 77.3 5.0 1.5 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.6 KFX92611.1 - 0.00026 21.1 1.4 0.00047 20.2 0.2 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Phage_lysozyme PF00959.14 KFX92612.1 - 8.2e-13 48.6 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.6 KFX92612.1 - 1.9e-05 24.7 0.3 0.00021 21.3 0.2 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain ABC1 PF03109.11 KFX92616.1 - 6e-30 103.6 0.0 9.7e-30 102.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Ank_2 PF12796.2 KFX92629.1 - 5.9e-94 308.5 10.1 1.1e-18 67.3 0.0 5.9 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92629.1 - 4.3e-65 212.4 13.7 5.7e-07 29.0 0.0 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.1 KFX92629.1 - 6.3e-57 183.8 3.1 7.1e-05 22.6 0.0 11.9 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 KFX92629.1 - 9.4e-56 185.2 12.2 1.3e-08 35.1 0.0 8.1 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX92629.1 - 3.4e-48 160.5 15.3 1.6e-09 37.6 0.1 10.2 1 1 9 10 10 10 9 Ankyrin repeats (many copies) F-box-like PF12937.2 KFX92629.1 - 0.00019 21.0 0.1 0.00078 19.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like RVP PF00077.15 KFX92629.1 - 0.0011 18.8 0.3 2.6 8.0 0.0 3.5 1 1 2 3 3 3 2 Retroviral aspartyl protease Shigella_OspC PF06128.6 KFX92629.1 - 0.01 15.3 0.0 16 4.8 0.0 3.7 3 1 1 4 4 4 0 Shigella flexneri OspC protein gag-asp_proteas PF13975.1 KFX92629.1 - 0.16 11.8 0.8 9.5 6.1 0.1 2.8 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease Ank_2 PF12796.2 KFX92630.1 - 5e-21 74.8 0.5 2.3e-17 63.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX92630.1 - 8.4e-20 70.3 0.3 5.5e-10 39.1 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KFX92630.1 - 1.8e-19 68.4 0.3 4.5e-05 23.0 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFX92630.1 - 3.7e-15 55.9 0.1 3.3e-06 27.4 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92630.1 - 1.1e-12 46.8 0.0 0.038 14.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Pyridox_oxidase PF01243.15 KFX92631.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF1604 PF07713.8 KFX92639.1 - 1.9e-37 126.8 3.8 2.9e-37 126.3 0.7 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KFX92639.1 - 1.9e-06 27.5 1.7 6.4e-06 25.8 1.1 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFX92639.1 - 0.17 11.7 4.8 0.065 13.0 0.5 2.5 2 1 1 3 3 3 0 DExH-box splicing factor binding site Pkinase PF00069.20 KFX92640.1 - 1.4e-77 260.4 0.0 2.6e-77 259.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92640.1 - 1.4e-38 132.4 0.1 1.2e-37 129.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFX92640.1 - 1e-17 63.3 0.1 1.7e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KFX92640.1 - 3.3e-05 23.0 0.0 6.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX92640.1 - 5.5e-05 22.2 0.0 0.00012 21.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like WaaY PF06176.6 KFX92640.1 - 0.0017 17.6 0.1 0.0031 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KFX92640.1 - 0.0075 16.0 0.0 0.043 13.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFX92640.1 - 0.0082 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Rcd1 PF04078.8 KFX92641.1 - 3.3e-131 435.9 3.9 3.9e-131 435.6 2.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.9 KFX92641.1 - 0.075 12.1 2.9 4.8 6.1 1.8 2.9 1 1 0 1 1 1 0 V-ATPase subunit H bZIP_1 PF00170.16 KFX92642.1 - 3.4e-05 23.7 0.7 9.1e-05 22.3 0.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KFX92642.1 - 0.085 12.4 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Peptidase_C50 PF03568.12 KFX92643.1 - 0.35 9.5 3.8 0.42 9.2 2.6 1.1 1 0 0 1 1 1 0 Peptidase family C50 Ycf54 PF10674.4 KFX92643.1 - 0.42 10.7 2.3 0.59 10.2 1.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2488) SPT6_acidic PF14632.1 KFX92643.1 - 1.2 9.3 6.2 1.4 9.1 3.8 1.5 1 1 0 1 1 1 0 Acidic N-terminal SPT6 PCI_Csn8 PF10075.4 KFX92646.1 - 1.5e-19 70.1 0.0 1.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KFX92646.1 - 2.3e-17 63.2 0.0 2.9e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cu_amine_oxid PF01179.15 KFX92647.1 - 1.5e-162 541.0 0.0 1.8e-162 540.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KFX92647.1 - 1.6e-12 47.3 0.0 3.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KFX92647.1 - 3.4e-06 27.0 0.0 7.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Amidohydro_1 PF01979.15 KFX92648.1 - 2.9e-20 73.2 0.1 2e-10 40.8 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KFX92648.1 - 1.4e-14 54.7 1.0 2.4e-14 54.0 0.7 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFX92648.1 - 1.1e-10 41.1 0.2 2.8e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFX92648.1 - 3.6e-06 26.4 0.9 0.0024 17.1 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Fungal_trans_2 PF11951.3 KFX92649.1 - 4.7e-06 25.4 1.4 4.7e-06 25.4 1.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Peptidase_C32 PF05411.7 KFX92650.1 - 0.044 13.5 0.1 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus putative proteinase DUF585 PF04522.7 KFX92650.1 - 0.12 11.7 0.1 1.7 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF585) PhyH PF05721.8 KFX92651.1 - 1.6e-26 93.6 0.0 3.1e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_16 PF00722.16 KFX92652.1 - 1.7e-09 37.1 0.0 3.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AA_permease_2 PF13520.1 KFX92653.1 - 2.3e-36 125.2 53.9 2.9e-36 124.9 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX92653.1 - 9e-18 63.8 45.5 1.2e-17 63.4 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease FAM220 PF15487.1 KFX92654.1 - 0.28 10.4 8.1 0.33 10.2 5.6 1.0 1 0 0 1 1 1 0 FAM220 family Pheromone PF08015.6 KFX92654.1 - 6 7.7 11.6 22 5.9 8.1 1.9 1 1 0 1 1 1 0 Fungal mating-type pheromone MFS_1 PF07690.11 KFX92655.1 - 8.7e-30 103.6 33.7 1.1e-29 103.3 22.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PARP PF00644.15 KFX92656.1 - 4.1e-60 202.7 1.2 4.5e-53 179.7 0.0 3.1 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KFX92656.1 - 1.2e-39 135.0 0.1 1.9e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KFX92656.1 - 2.6e-19 68.9 1.1 2.6e-19 68.9 0.8 2.5 2 1 0 2 2 2 1 WGR domain BRCT PF00533.21 KFX92656.1 - 4.3e-11 42.7 0.0 8.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFX92656.1 - 1.5e-07 31.1 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Suf PF05843.9 KFX92656.1 - 0.55 9.9 3.8 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Metallophos PF00149.23 KFX92657.1 - 5.6e-34 117.2 0.7 9.1e-34 116.6 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KFX92657.1 - 7.4e-16 57.9 0.1 2.8e-15 56.1 0.1 2.1 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KFX92657.1 - 7e-10 38.0 0.1 5.6e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 KFX92657.1 - 0.074 12.8 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Mucin PF01456.12 KFX92658.1 - 0.069 12.9 9.9 0.14 11.9 6.8 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.17 KFX92659.1 - 8.9e-29 100.3 0.0 1.7e-28 99.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S64 PF08192.6 KFX92660.1 - 9.9e-10 37.4 0.3 5.8e-09 34.8 0.2 1.9 1 1 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 KFX92660.1 - 9.7e-05 22.3 0.0 0.00051 20.0 0.0 2.2 2 1 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 KFX92660.1 - 0.032 13.1 0.5 0.067 12.1 0.1 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.21 KFX92660.1 - 0.45 10.0 1.5 14 5.1 0.3 2.6 1 1 1 3 3 3 0 Trypsin Fungal_trans_2 PF11951.3 KFX92661.1 - 1.5e-43 148.8 0.0 2.1e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92661.1 - 1.8e-08 34.1 11.2 3.4e-08 33.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KFX92661.1 - 0.13 11.9 6.1 0.61 9.9 4.2 2.2 1 0 0 1 1 1 0 AT hook motif Pyrophosphatase PF00719.14 KFX92666.1 - 3.9e-52 175.8 0.1 4.9e-52 175.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 KFX92667.1 - 5.7e-47 160.0 0.0 1.7e-46 158.5 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KFX92667.1 - 0.17 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Ldh_2 PF02615.9 KFX92668.1 - 2.6e-63 213.7 0.1 3.2e-63 213.4 0.1 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NAD_binding_2 PF03446.10 KFX92669.1 - 7e-34 117.0 0.0 9e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFX92669.1 - 1.7e-18 66.8 0.0 2.8e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFX92669.1 - 0.00021 21.6 0.0 0.00089 19.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KFX92669.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Lactamase_B PF00753.22 KFX92671.1 - 2.5e-07 30.5 1.2 2e-06 27.5 0.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX92671.1 - 3.1e-07 30.1 0.3 4.9e-07 29.4 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.15 KFX92672.1 - 4e-20 71.4 0.2 1.3e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 KFX92673.1 - 1.1e-26 93.4 32.1 1.5e-26 92.9 22.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4473 PF14747.1 KFX92673.1 - 0.0051 16.9 0.7 0.01 16.0 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) FAD_binding_2 PF00890.19 KFX92674.1 - 8.2e-41 140.2 0.0 5.3e-40 137.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFX92674.1 - 1.9e-10 40.3 0.5 8.9e-08 31.6 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 KFX92674.1 - 9e-10 37.9 0.6 1.9e-09 36.9 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX92674.1 - 5.2e-06 25.1 5.8 0.0015 17.1 0.1 3.1 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_2 PF07992.9 KFX92674.1 - 3.3e-05 23.8 1.9 0.0089 15.9 1.6 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX92674.1 - 0.00082 18.3 5.1 0.0086 14.9 0.3 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFX92674.1 - 0.0099 14.9 0.1 0.059 12.4 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFX92674.1 - 0.015 15.2 0.6 0.048 13.7 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KFX92674.1 - 0.02 14.0 0.3 0.15 11.1 0.2 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.1 KFX92674.1 - 0.03 14.3 0.9 0.89 9.5 0.7 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX92674.1 - 0.13 11.3 0.5 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Alginate_lyase2 PF08787.6 KFX92674.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Alginate lyase Aldedh PF00171.17 KFX92675.1 - 6.8e-152 506.0 0.1 7.6e-152 505.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX92675.1 - 0.008 14.9 0.2 0.019 13.7 0.2 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) FtsZ_C PF12327.3 KFX92675.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DUF1487 PF07368.6 KFX92675.1 - 0.14 11.3 0.0 0.46 9.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Fungal_trans PF04082.13 KFX92676.1 - 1.2e-23 83.3 0.1 2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92676.1 - 1.3e-07 31.4 13.2 2.5e-07 30.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KFX92677.1 - 3.9e-131 437.5 0.1 4.5e-131 437.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX92677.1 - 0.015 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cullin PF00888.17 KFX92678.1 - 1.4e-52 179.0 0.0 2.6e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KFX92678.1 - 6.8e-18 64.6 0.2 2.2e-17 63.0 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 KFX92678.1 - 0.094 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator Sugar_tr PF00083.19 KFX92679.1 - 3.6e-115 385.1 15.1 5.8e-115 384.4 10.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX92679.1 - 5.1e-25 87.9 45.3 1.2e-23 83.3 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX92679.1 - 0.00037 18.8 3.6 0.00037 18.8 2.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Nop14 PF04147.7 KFX92685.1 - 0.057 11.3 9.7 0.12 10.2 6.7 1.5 1 0 0 1 1 1 0 Nop14-like family Scytalone_dh PF02982.9 KFX92687.1 - 7.9e-55 184.8 0.2 1.2e-54 184.2 0.1 1.2 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KFX92687.1 - 0.042 13.7 0.0 0.064 13.1 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain zf-C2H2 PF00096.21 KFX92688.1 - 3.9e-08 33.1 13.8 0.00013 22.0 1.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX92688.1 - 5.6e-06 26.3 20.1 0.00024 21.1 1.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 KFX92688.1 - 6.2e-05 22.8 9.5 6.2e-05 22.8 6.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 KFX92688.1 - 0.0027 17.7 5.2 0.03 14.4 0.6 2.7 1 1 1 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX92688.1 - 0.056 13.6 5.0 3.9 7.8 0.5 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KFX92688.1 - 0.068 13.4 12.8 0.054 13.7 2.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFX92688.1 - 1.2 9.1 4.8 6.1 6.8 0.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short_C2 PF13561.1 KFX92689.1 - 2.8e-27 96.0 0.0 4.7e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX92689.1 - 1.4e-26 93.3 0.0 2.3e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX92689.1 - 4.9e-11 42.6 0.0 9.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX92689.1 - 0.069 12.5 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KFX92689.1 - 0.089 11.8 0.0 0.27 10.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 KFX92690.1 - 2.6e-50 171.2 0.0 6.2e-50 170.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Cu-oxidase_3 PF07732.10 KFX92691.1 - 2.2e-42 143.5 0.7 2.2e-42 143.5 0.5 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX92691.1 - 6.5e-31 106.6 11.2 9.4e-30 102.9 1.9 4.0 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KFX92691.1 - 1.5e-22 80.2 4.6 4.1e-22 78.7 0.0 3.5 4 1 1 5 5 5 1 Multicopper oxidase NPR3 PF03666.8 KFX92691.1 - 0.25 9.8 0.1 0.36 9.3 0.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 UEV PF05743.8 KFX92693.1 - 6.4e-38 129.1 0.0 8.8e-38 128.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain RNA_pol_Rpb2_6 PF00562.23 KFX92694.1 - 3.6e-123 411.1 0.1 1.7e-122 408.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFX92694.1 - 5e-62 208.4 0.0 9.4e-62 207.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFX92694.1 - 3.5e-49 166.8 0.0 7e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KFX92694.1 - 6.5e-25 86.7 0.3 1.9e-24 85.2 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 ADH_N PF08240.7 KFX92694.1 - 3.2e-24 84.7 4.5 1.1e-23 83.1 2.8 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_Rpb2_3 PF04565.11 KFX92694.1 - 6.7e-23 80.2 0.0 1.4e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KFX92694.1 - 9.3e-21 73.5 0.1 2.3e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N PF00107.21 KFX92694.1 - 2.5e-19 69.1 0.0 7.2e-19 67.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX92694.1 - 5e-09 37.1 0.0 1.3e-08 35.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNA_pol_Rpb2_7 PF04560.15 KFX92694.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 2-Hacid_dh_C PF02826.14 KFX92694.1 - 0.02 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 KFX92694.1 - 0.12 12.1 0.5 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) DUF3539 PF12058.3 KFX92695.1 - 0.11 12.3 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) V-ATPase_G PF03179.10 KFX92696.1 - 2.9e-33 114.2 15.4 3.3e-33 114.1 10.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KFX92696.1 - 0.0034 17.1 8.6 0.0034 17.1 6.0 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) Nop25 PF09805.4 KFX92696.1 - 0.071 13.1 14.9 0.088 12.8 10.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RE_AlwI PF09491.5 KFX92696.1 - 0.092 11.1 4.5 0.11 10.9 3.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3552 PF12072.3 KFX92696.1 - 0.15 11.2 19.7 0.03 13.5 8.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) AAA_13 PF13166.1 KFX92696.1 - 0.34 9.3 9.5 0.37 9.1 6.6 1.0 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.3 KFX92696.1 - 0.51 10.0 5.3 0.59 9.7 3.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region HrpE PF06188.7 KFX92696.1 - 0.83 9.3 8.7 1 9.1 2.0 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF1423 PF07227.6 KFX92696.1 - 0.99 7.9 9.5 1.1 7.8 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) RRF PF01765.14 KFX92696.1 - 1 8.8 14.3 1.5 8.2 9.3 1.7 1 1 1 2 2 2 0 Ribosome recycling factor Colicin-DNase PF12639.2 KFX92696.1 - 1.9 8.8 6.9 1.9 8.8 3.1 1.8 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Vfa1 PF08432.5 KFX92696.1 - 2.5 8.0 12.2 3 7.8 8.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 KFX92696.1 - 2.9 6.8 8.4 3.3 6.6 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 KFX92696.1 - 4 5.5 13.3 4.2 5.5 9.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein vATP-synt_E PF01991.13 KFX92696.1 - 4.6 6.4 19.4 0.49 9.6 6.1 2.1 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit SAPS PF04499.10 KFX92696.1 - 8 4.9 8.0 8.2 4.9 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF883 PF05957.8 KFX92696.1 - 8.6 6.8 10.5 15 6.0 4.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Arrestin_N PF00339.24 KFX92697.1 - 1.1e-12 48.0 0.0 7.9e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain PGAP1 PF07819.8 KFX92697.1 - 6e-06 26.0 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFX92697.1 - 2e-05 23.9 0.0 3.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KFX92697.1 - 5.5e-05 23.1 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KFX92697.1 - 0.00089 18.3 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KFX92697.1 - 0.034 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KFX92697.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 KFX92697.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) SHS2_Rpb7-N PF03876.12 KFX92699.1 - 2.8e-07 30.5 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AIF_C PF14721.1 KFX92699.1 - 3.2 8.0 6.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ras PF00071.17 KFX92705.1 - 9e-56 187.7 0.0 1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX92705.1 - 9.4e-16 58.3 0.0 1.5e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX92705.1 - 3.2e-07 29.7 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX92705.1 - 0.00071 19.0 0.0 0.0032 16.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFX92705.1 - 0.0015 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX92705.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFX92705.1 - 0.11 11.9 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribonuc_red_lgC PF02867.10 KFX92706.1 - 5e-217 721.7 0.0 8.3e-217 720.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KFX92706.1 - 1.3e-25 89.0 0.1 3.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KFX92706.1 - 3.8e-16 59.2 0.2 4.1e-15 55.9 0.1 2.6 2 0 0 2 2 2 1 ATP cone domain SET PF00856.23 KFX92707.1 - 3.8e-12 46.8 0.0 4.9e-10 39.9 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF3328 PF11807.3 KFX92714.1 - 1.2e-21 77.3 0.3 1.4e-12 47.7 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.1 KFX92715.1 - 8.3e-24 84.3 0.0 9.7e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX92715.1 - 7.5e-09 35.5 0.0 7.5e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFX92715.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX92715.1 - 0.0034 17.1 0.0 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein ELK PF03789.8 KFX92715.1 - 0.06 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 ELK domain Acetyltransf_7 PF13508.1 KFX92715.1 - 0.084 13.0 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Vps54 PF07928.7 KFX92717.1 - 4.2e-42 143.4 0.0 7.6e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 Vps54-like protein Phage_prot_Gp6 PF05133.9 KFX92717.1 - 0.0064 15.1 0.6 0.009 14.6 0.4 1.2 1 0 0 1 1 1 1 Phage portal protein, SPP1 Gp6-like Acetyltransf_7 PF13508.1 KFX92721.1 - 5e-08 32.9 0.0 7.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX92721.1 - 1.8e-07 31.3 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX92721.1 - 6.1e-06 26.1 0.0 8.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFX92721.1 - 0.00013 21.8 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX92721.1 - 0.0054 16.5 0.1 0.01 15.6 0.0 1.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KFX92721.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 KFX92721.1 - 0.028 14.2 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_B_palm PF14792.1 KFX92722.1 - 1.8e-33 114.9 0.0 3.1e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KFX92722.1 - 8e-23 79.9 0.0 7.3e-22 76.8 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KFX92722.1 - 3.7e-18 64.7 0.8 7.6e-18 63.8 0.6 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KFX92722.1 - 1.9e-15 56.7 1.8 3.7e-15 55.8 0.3 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain BRCT PF00533.21 KFX92722.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HHH_2 PF12826.2 KFX92722.1 - 0.064 13.1 0.2 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif PTCB-BRCT PF12738.2 KFX92722.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain Sugar_tr PF00083.19 KFX92723.1 - 4.4e-95 318.8 27.2 5.2e-95 318.6 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX92723.1 - 4.1e-39 134.3 43.2 1.3e-35 122.8 13.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX92723.1 - 5.3e-06 25.0 15.1 0.00025 19.6 2.3 3.6 2 2 0 3 3 3 2 MFS/sugar transport protein Asn_synthase PF00733.16 KFX92724.1 - 1.1e-47 162.6 0.0 2.9e-46 158.0 0.0 2.2 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFX92724.1 - 7.6e-08 32.1 0.0 2e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFX92724.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.13 KFX92725.1 - 6.4e-30 103.2 0.1 1.1e-29 102.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KFX92725.1 - 2.2e-10 39.7 0.0 4.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain TPR_9 PF13371.1 KFX92726.1 - 0.00093 19.0 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX92726.1 - 0.0014 18.1 0.0 0.0049 16.4 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92726.1 - 0.0027 17.3 0.1 0.031 13.8 0.0 2.6 3 0 0 3 3 3 1 TPR repeat SHNi-TPR PF10516.4 KFX92726.1 - 0.0035 16.5 0.0 0.01 15.0 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.12 KFX92726.1 - 0.0055 16.5 2.4 0.0071 16.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPP_enzyme_N PF02776.13 KFX92727.1 - 3.4e-56 189.4 0.1 1.8e-55 187.0 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFX92727.1 - 3.5e-49 166.3 0.1 2.5e-47 160.2 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX92727.1 - 3.4e-36 124.0 0.4 1.6e-35 121.8 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.20 KFX92728.1 - 7.9e-56 189.0 0.0 1.4e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92728.1 - 5e-31 107.7 0.0 7.6e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX92728.1 - 0.00092 19.0 0.1 0.0039 16.9 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFX92728.1 - 0.0033 16.4 0.0 0.011 14.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFX92728.1 - 0.0039 16.2 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_6 PF01341.12 KFX92729.1 - 1.8e-85 287.0 0.3 2.3e-85 286.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SAC3_GANP PF03399.11 KFX92730.1 - 3.8e-09 36.4 0.3 6.8e-09 35.5 0.2 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFX92730.1 - 4.2e-05 23.3 0.0 8.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HlyIII PF03006.15 KFX92731.1 - 7.6e-59 198.8 14.8 9e-59 198.5 10.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related adh_short PF00106.20 KFX92732.1 - 1.8e-34 119.0 3.0 2.6e-34 118.5 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX92732.1 - 1e-23 84.3 0.6 2.1e-23 83.3 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX92732.1 - 6.4e-18 65.0 1.4 8.4e-18 64.6 1.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFX92732.1 - 0.0028 17.3 1.4 0.0045 16.6 1.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KFX92732.1 - 0.0072 16.1 1.3 0.01 15.6 0.4 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Gly_rich_SFCGS PF14272.1 KFX92732.1 - 0.023 14.5 1.2 0.53 10.1 0.6 2.4 2 0 0 2 2 2 0 Glycine-rich SFCGS Saccharop_dh PF03435.13 KFX92732.1 - 0.043 12.7 0.3 0.063 12.2 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_25 PF13649.1 KFX92732.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_2 PF00535.21 KFX92733.1 - 1.6e-28 99.4 0.0 2.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFX92733.1 - 9.6e-11 41.9 0.0 1.5e-10 41.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFX92733.1 - 2.7e-09 36.5 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KFX92733.1 - 0.0025 18.0 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KFX92733.1 - 0.023 13.9 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 TFR_dimer PF04253.10 KFX92734.1 - 3.9e-23 81.3 0.0 7.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFX92734.1 - 2.8e-18 66.2 0.0 5.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFX92734.1 - 3.4e-07 29.9 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFX92734.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cyt-b5 PF00173.23 KFX92735.1 - 1.8e-12 46.8 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SufE PF02657.10 KFX92735.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain TMA7 PF09072.5 KFX92736.1 - 4.1e-21 75.1 17.9 4.6e-21 75.0 12.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 KFX92737.1 - 1.2e-52 178.6 0.1 1.8e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92737.1 - 4e-24 85.0 0.3 1.2e-23 83.5 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX92737.1 - 0.0077 15.0 0.1 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KFX92737.1 - 0.056 12.7 0.3 0.14 11.4 0.2 1.7 1 1 0 1 1 1 0 RIO1 family TPR_19 PF14559.1 KFX92738.1 - 1.2e-08 35.1 0.4 1.8e-08 34.5 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92738.1 - 3e-05 23.5 1.0 0.024 14.2 0.0 1.9 1 1 1 2 2 2 2 TPR repeat Coatomer_E PF04733.9 KFX92738.1 - 5.8e-05 22.4 0.1 6.6e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.1 KFX92738.1 - 0.0015 18.9 0.1 0.072 13.7 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX92738.1 - 0.0027 18.3 0.0 0.01 16.4 0.0 1.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX92738.1 - 0.0052 17.1 0.2 0.15 12.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX92738.1 - 0.0074 16.1 0.2 0.47 10.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX92738.1 - 0.025 14.4 0.2 0.054 13.4 0.1 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFX92738.1 - 0.14 12.0 0.9 0.8 9.7 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DASH_Ask1 PF08655.5 KFX92742.1 - 7.4e-34 115.3 0.0 1.1e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Ask1 Prok-JAB PF14464.1 KFX92742.1 - 0.11 12.1 0.6 0.16 11.5 0.4 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF3073 PF11273.3 KFX92742.1 - 0.75 10.3 4.5 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) O-FucT PF10250.4 KFX92743.1 - 8.3e-07 28.4 0.0 0.00034 19.8 0.0 2.6 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase 3HCDH_N PF02737.13 KFX92744.1 - 4.9e-42 143.6 0.0 7.1e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFX92744.1 - 1.7e-09 37.9 0.0 3.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 KFX92744.1 - 0.00019 20.6 0.0 0.00044 19.4 0.0 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFX92744.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX92744.1 - 0.072 13.5 0.1 0.46 10.9 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 KFX92744.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CBM_1 PF00734.13 KFX92745.1 - 2.2e-14 52.7 12.7 5.7e-14 51.4 8.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX92745.1 - 0.16 12.0 3.0 0.29 11.1 2.1 1.4 1 0 0 1 1 1 0 Toxin 7 DUF3074 PF11274.3 KFX92748.1 - 2.2e-29 102.4 0.0 2.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Formyl_trans_N PF00551.14 KFX92749.1 - 1.9e-37 128.5 0.0 2.3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 KFX92749.1 - 0.046 13.3 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase GDI PF00996.13 KFX92756.1 - 1.2e-176 587.3 0.0 1.5e-176 586.9 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor MRP-L47 PF06984.8 KFX92756.1 - 1.1e-20 73.3 0.3 2.1e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NAD_binding_8 PF13450.1 KFX92756.1 - 0.098 12.6 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-H2C2_2 PF13465.1 KFX92757.1 - 6.3e-06 26.2 1.2 6.3e-06 26.2 0.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX92757.1 - 4.2e-05 23.5 13.7 0.0034 17.6 3.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFX92757.1 - 0.0014 18.7 3.2 0.0026 17.8 2.2 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF3464 PF11947.3 KFX92757.1 - 0.1 12.0 5.1 0.93 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) zf-C2H2_jaz PF12171.3 KFX92757.1 - 0.35 11.0 3.3 9.6 6.4 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFX92757.1 - 0.44 10.3 6.4 0.63 9.8 0.4 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 KFX92757.1 - 8.2 6.9 24.2 0.18 12.1 4.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type FimP PF09766.4 KFX92757.1 - 9.3 5.2 13.8 15 4.4 9.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Pkinase PF00069.20 KFX92765.1 - 2.6e-10 39.8 0.0 3.3e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92765.1 - 0.014 14.4 0.0 0.036 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1768 PF08719.6 KFX92767.1 - 6.6e-49 165.6 0.0 7.9e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RepC PF06504.6 KFX92767.1 - 0.041 12.8 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Replication protein C (RepC) Glutaredoxin PF00462.19 KFX92775.1 - 9.2e-10 38.3 0.0 1.7e-09 37.5 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin CYSTM PF12734.2 KFX92776.1 - 5.9e-12 45.4 16.2 5.9e-12 45.4 11.2 5.0 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 KFX92776.1 - 5.7 6.9 36.3 6.8 6.7 25.2 1.1 1 0 0 1 1 1 0 Proline-rich A_deaminase PF00962.17 KFX92777.1 - 5.8e-111 370.5 0.1 7.4e-111 370.2 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 KFX92778.1 - 1.7e-92 309.6 6.2 2.1e-92 309.3 4.3 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KFX92778.1 - 8.8e-05 21.7 4.8 0.00027 20.1 3.3 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KFX92778.1 - 0.00038 20.6 14.6 0.01 16.0 2.0 3.2 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Pox_A14 PF05767.7 KFX92778.1 - 0.11 12.4 2.0 0.14 12.1 0.0 2.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 TPT PF03151.11 KFX92778.1 - 0.17 11.5 17.5 0.024 14.2 6.0 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family LSM PF01423.17 KFX92780.1 - 7.6e-16 57.4 1.0 1e-15 56.9 0.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFX92780.1 - 0.025 14.5 0.1 0.032 14.1 0.1 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 KFX92780.1 - 0.037 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Muskelin_N PF06588.6 KFX92780.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.3 1 1 0 1 1 1 0 Muskelin N-terminus DRMBL PF07522.9 KFX92781.1 - 2.6e-35 120.7 0.0 6.1e-35 119.5 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KFX92781.1 - 1.5e-11 44.2 0.0 2.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rad50_zn_hook PF04423.9 KFX92781.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Sugar_tr PF00083.19 KFX92783.1 - 4.7e-45 154.0 10.5 5.6e-45 153.7 7.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX92783.1 - 5.3e-16 58.2 14.9 6e-16 58.1 9.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX92783.1 - 2.3e-06 26.2 4.4 2.3e-06 26.2 3.0 2.3 3 0 0 3 3 3 1 MFS/sugar transport protein STE3 PF02076.10 KFX92788.1 - 4.9e-85 285.0 18.1 5.6e-85 284.8 12.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4131 PF13567.1 KFX92788.1 - 0.0075 15.6 0.7 0.0075 15.6 0.5 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4131) Mito_carr PF00153.22 KFX92795.1 - 1.4e-33 114.4 0.2 8.3e-21 73.5 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3611 PF12263.3 KFX92795.1 - 0.023 14.0 0.2 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Myb_DNA-binding PF00249.26 KFX92798.1 - 1.4e-12 47.4 1.5 4.9e-07 29.6 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX92798.1 - 3.6e-11 43.0 1.5 3e-06 27.2 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.16 KFX92802.1 - 7.9e-43 145.8 4.0 1.2e-42 145.3 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KFX92802.1 - 0.011 15.7 11.9 0.023 14.6 8.3 1.5 1 0 0 1 1 1 0 Chitin recognition protein WAP PF00095.16 KFX92802.1 - 0.028 14.3 4.2 0.055 13.4 2.9 1.4 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' zf-C2H2_3 PF13878.1 KFX92804.1 - 3.5e-08 32.8 0.1 6.1e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO ASF1_hist_chap PF04729.8 KFX92810.1 - 2.7e-62 208.9 0.0 4e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone zf-RING_3 PF14369.1 KFX92811.1 - 1.2 9.2 7.4 1.3 9.1 0.7 2.4 2 0 0 2 2 2 0 zinc-finger OrfB_Zn_ribbon PF07282.6 KFX92811.1 - 1.5 8.5 4.2 7.7 6.2 2.9 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain GTP_EFTU PF00009.22 KFX92812.1 - 3.2e-38 131.0 2.3 3.2e-38 131.0 1.6 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFX92812.1 - 1e-23 83.2 0.5 3.6e-23 81.5 0.2 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFX92812.1 - 1.7e-12 47.2 2.0 1.1e-05 25.4 0.0 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX92812.1 - 4.4e-07 29.8 0.1 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 KFX92812.1 - 1.4e-05 24.5 0.0 3.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 KFX92812.1 - 2.1e-05 25.0 0.0 5.9e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KFX92812.1 - 0.00069 19.1 0.3 0.0024 17.3 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KFX92812.1 - 0.001 18.3 0.5 0.002 17.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 KFX92812.1 - 0.0083 15.3 0.0 0.022 13.9 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFX92812.1 - 0.01 15.1 0.2 0.039 13.2 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B VHS PF00790.14 KFX92814.1 - 3.7e-45 153.0 0.0 1.4e-44 151.1 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFX92814.1 - 1.6e-24 85.7 0.5 4e-24 84.5 0.3 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KFX92814.1 - 5.6e-19 68.5 0.1 1.3e-18 67.4 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF2360 PF10152.4 KFX92814.1 - 4.4 7.5 9.1 13 6.1 4.7 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Glyco_hydro_76 PF03663.9 KFX92819.1 - 1.1e-79 268.5 3.7 1.3e-79 268.2 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 SKG6 PF08693.5 KFX92819.1 - 0.00026 20.2 1.7 0.00066 18.9 1.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 KFX92819.1 - 0.0011 18.3 0.1 0.0023 17.1 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Pex14_N PF04695.8 KFX92819.1 - 0.039 13.9 1.7 0.071 13.1 1.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1517 PF07466.6 KFX92819.1 - 0.081 11.9 1.1 0.13 11.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) PRCC PF10253.4 KFX92819.1 - 0.085 13.5 1.2 0.13 12.9 0.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4366 PF14283.1 KFX92819.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DAP10 PF07213.6 KFX92819.1 - 0.16 11.7 1.9 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 DAP10 membrane protein Pyr_redox_2 PF07992.9 KFX92820.1 - 7.6e-18 65.1 0.1 1e-17 64.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX92820.1 - 1.3e-06 28.2 1.1 0.059 13.1 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFX92820.1 - 3.2e-05 22.9 0.8 0.00067 18.6 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KFX92820.1 - 0.00012 21.0 1.5 0.00089 18.2 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX92820.1 - 0.00021 19.8 0.1 0.017 13.5 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFX92820.1 - 0.0015 18.6 0.3 0.15 12.1 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX92820.1 - 0.0016 17.5 1.0 0.0027 16.8 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFX92820.1 - 0.0028 17.6 0.1 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX92820.1 - 0.0065 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFX92820.1 - 0.0086 14.9 4.4 0.11 11.3 0.6 2.6 2 1 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KFX92820.1 - 0.018 13.9 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein vMSA PF00695.14 KFX92821.1 - 0.0033 16.6 1.8 0.0044 16.2 1.2 1.1 1 0 0 1 1 1 1 Major surface antigen from hepadnavirus SKG6 PF08693.5 KFX92821.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CTV_P6 PF06706.6 KFX92821.1 - 0.041 13.3 1.2 0.081 12.4 0.8 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein DUF912 PF06024.7 KFX92821.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rax2 PF12768.2 KFX92821.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF566 PF04484.7 KFX92821.1 - 5.6 6.3 11.2 7.5 5.9 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Herpes_BLLF1 PF05109.8 KFX92821.1 - 7.2 4.4 24.5 8.3 4.2 17.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Trypan_PARP PF05887.6 KFX92821.1 - 8.2 6.2 16.5 7 6.4 10.5 1.5 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Podoplanin PF05808.6 KFX92822.1 - 0.00021 20.9 3.7 0.00038 20.0 2.6 1.4 1 0 0 1 1 1 1 Podoplanin Adeno_E3_CR2 PF02439.10 KFX92822.1 - 0.0011 18.5 0.4 0.002 17.6 0.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1517 PF07466.6 KFX92822.1 - 0.0053 15.7 1.6 0.0075 15.2 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) SKG6 PF08693.5 KFX92822.1 - 0.02 14.1 0.4 0.053 12.8 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.6 KFX92822.1 - 0.78 7.5 11.0 0.94 7.2 7.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF515 PF04415.7 KFX92822.1 - 1.1 7.3 9.6 1.9 6.6 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.11 KFX92823.1 - 3.2e-22 78.7 41.5 3.2e-22 78.7 28.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily GtrA PF04138.9 KFX92823.1 - 4.2 7.3 20.7 1.4 8.8 6.1 4.2 2 2 1 3 3 3 0 GtrA-like protein Methyltransf_2 PF00891.13 KFX92824.1 - 1.2e-12 47.5 0.0 1.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFX92824.1 - 0.12 12.9 0.0 0.4 11.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Claudin_2 PF13903.1 KFX92826.1 - 0.011 15.4 0.1 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction FliE PF02049.13 KFX92826.1 - 0.064 13.2 0.6 0.18 11.8 0.4 1.8 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE DUF4231 PF14015.1 KFX92826.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Cellulase PF00150.13 KFX92827.1 - 2.9e-14 52.9 5.8 4.5e-14 52.3 4.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.4 KFX92828.1 - 1.1e-30 105.5 0.0 2.3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Piwi PF02171.12 KFX92829.1 - 3.5e-71 239.6 1.1 5.2e-71 239.0 0.8 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFX92829.1 - 7.4e-13 47.9 0.3 2.3e-12 46.3 0.2 1.7 1 1 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFX92829.1 - 9.7e-13 47.2 0.0 2.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 KFX92830.1 - 3.9e-84 282.6 0.4 3e-81 273.2 0.0 2.9 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KFX92830.1 - 0.00068 20.0 0.1 0.28 11.9 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX92830.1 - 0.0017 19.0 0.0 0.047 14.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 KFX92830.1 - 0.0073 16.0 0.1 0.42 10.4 0.1 2.5 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat PP28 PF10252.4 KFX92832.1 - 2.4e-29 101.1 14.1 2.4e-29 101.1 9.8 3.1 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Abhydrolase_5 PF12695.2 KFX92834.1 - 2e-15 56.7 0.2 2.8e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX92834.1 - 3.7e-15 56.4 0.5 6.6e-15 55.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX92834.1 - 2.4e-08 33.8 0.1 2.4e-07 30.5 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX92834.1 - 3e-08 33.1 0.0 5.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFX92834.1 - 1.6e-05 24.5 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 KFX92834.1 - 0.0033 17.1 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 KFX92834.1 - 0.0095 15.5 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.8 KFX92834.1 - 0.011 15.3 0.4 0.02 14.4 0.2 1.5 1 1 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.11 KFX92834.1 - 0.015 14.7 0.4 0.18 11.2 0.1 2.4 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KFX92834.1 - 0.041 13.4 0.2 0.066 12.7 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein DUF1072 PF06380.6 KFX92834.1 - 0.1 12.3 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Hydrolase_4 PF12146.3 KFX92834.1 - 0.11 12.3 0.2 0.4 10.5 0.1 2.0 1 1 0 1 1 1 0 Putative lysophospholipase NMT_C PF02799.10 KFX92835.1 - 3.7e-77 258.0 0.0 5.3e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFX92835.1 - 7.4e-76 253.2 0.0 1.2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KFX92835.1 - 0.011 15.5 0.1 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Molydop_binding PF01568.16 KFX92835.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RhoGAP PF00620.22 KFX92835.1 - 0.052 13.1 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain DUF427 PF04248.7 KFX92835.1 - 0.054 13.1 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) SOG2 PF10428.4 KFX92836.1 - 0.0047 15.6 4.5 0.0049 15.5 3.1 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein WSC PF01822.14 KFX92837.1 - 2.2e-18 65.9 7.9 3.6e-18 65.2 5.5 1.3 1 0 0 1 1 1 1 WSC domain DUF3439 PF11921.3 KFX92837.1 - 0.97 9.1 10.4 0.61 9.8 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ank_2 PF12796.2 KFX92839.1 - 4.4e-47 158.3 6.5 9.3e-18 64.3 0.1 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92839.1 - 1.3e-42 141.4 8.1 2.2e-07 30.3 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFX92839.1 - 1.2e-35 121.2 7.6 3.7e-10 40.0 0.1 6.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92839.1 - 2.3e-34 113.9 4.1 8.4e-05 22.4 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KFX92839.1 - 5.5e-28 96.3 11.2 6.6e-07 29.3 0.1 6.7 3 2 2 6 6 6 6 Ankyrin repeats (many copies) COesterase PF00135.23 KFX92840.1 - 3.4e-93 313.1 0.0 4.1e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX92840.1 - 4.4e-05 23.1 0.0 0.00017 21.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX92840.1 - 0.0056 15.9 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family dUTPase PF00692.14 KFX92841.1 - 1e-13 50.8 0.0 1.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 KFX92841.1 - 0.00059 18.3 0.0 0.0016 16.9 0.0 1.6 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Sulfatase PF00884.18 KFX92842.1 - 1.8e-63 214.6 0.4 2.4e-63 214.2 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFX92842.1 - 0.0011 18.3 0.2 0.085 12.1 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 KFX92843.1 - 3.7e-21 75.2 33.6 1.4e-18 66.8 9.0 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX92843.1 - 4e-05 22.3 1.1 9.1e-05 21.2 0.8 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 KFX92845.1 - 1.5e-30 106.8 0.0 1.8e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX92845.1 - 1.4e-21 77.1 0.1 1.3e-17 64.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX92845.1 - 1.5e-14 53.9 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KFX92845.1 - 5.1e-06 25.5 0.0 7e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.9 KFX92845.1 - 1.1e-05 24.1 0.0 2.3e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 KFX92845.1 - 2.1e-05 24.2 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KFX92845.1 - 0.00019 21.1 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KFX92845.1 - 0.0023 17.0 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KFX92845.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KFX92845.1 - 0.038 13.5 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KFX92845.1 - 0.059 12.7 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 KFX92845.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 KFX92845.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.15 KFX92845.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 KFX92845.1 - 0.16 11.2 0.1 4 6.6 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF202 PF02656.10 KFX92846.1 - 1.3 9.2 4.2 17 5.7 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF202) APH PF01636.18 KFX92847.1 - 1.2e-11 44.8 0.2 3e-11 43.5 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KFX92847.1 - 1.3e-07 31.0 0.0 0.00012 21.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Choline_kinase PF01633.15 KFX92847.1 - 4.4e-07 29.7 0.1 2.3e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFX92847.1 - 0.00016 20.7 0.0 0.00043 19.4 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX92847.1 - 0.00039 19.8 0.3 0.0017 17.7 0.0 2.0 2 1 0 2 2 2 1 RIO1 family DUF553 PF04473.7 KFX92847.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.4 1 1 0 1 1 1 0 Transglutaminase-like domain Pkinase_Tyr PF07714.12 KFX92847.1 - 0.024 13.7 0.0 0.057 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase SNARE PF05739.14 KFX92851.1 - 2.9e-17 62.1 2.3 4.6e-17 61.4 0.2 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFX92851.1 - 5e-15 55.5 1.0 5e-15 55.5 0.7 2.7 3 0 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KFX92851.1 - 0.0034 16.9 7.8 0.033 13.7 0.1 2.9 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 KFX92851.1 - 0.0066 15.8 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 Integral membrane protein Sed5p NPV_P10 PF05531.7 KFX92851.1 - 0.17 12.1 8.0 4.5 7.6 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 KFX92851.1 - 1.8 9.0 6.6 1.9 8.9 0.1 3.3 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.6 KFX92851.1 - 3.5 6.1 7.6 0.19 10.3 0.8 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein CBS PF00571.23 KFX92852.1 - 0.0015 18.3 0.0 0.43 10.4 0.0 2.5 2 1 1 3 3 3 2 CBS domain Glyco_hydro_43 PF04616.9 KFX92853.1 - 1.3e-31 109.8 3.0 1.6e-31 109.5 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PIH1 PF08190.7 KFX92856.1 - 0.55 9.6 8.0 0.59 9.5 5.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF566 PF04484.7 KFX92856.1 - 1.1 8.6 19.0 1.3 8.4 13.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Plasmodium_Vir PF05795.6 KFX92856.1 - 2.4 7.2 8.8 2.9 7.0 6.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GCOM2 PF15328.1 KFX92856.1 - 2.4 7.8 9.5 2.7 7.6 6.6 1.0 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF605 PF04652.11 KFX92856.1 - 2.9 7.1 18.1 3.4 6.9 12.5 1.0 1 0 0 1 1 1 0 Vta1 like Presenilin PF01080.12 KFX92856.1 - 3.7 6.2 11.2 4.3 6.0 7.8 1.2 1 0 0 1 1 1 0 Presenilin Mitofilin PF09731.4 KFX92856.1 - 4.4 5.8 12.1 4.7 5.7 8.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1675 PF07897.6 KFX92856.1 - 4.7 6.9 16.9 5.9 6.6 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Pneumo_att_G PF05539.6 KFX92856.1 - 6.5 6.0 26.9 7.3 5.8 18.6 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G NPR3 PF03666.8 KFX92856.1 - 6.6 5.1 8.1 7.2 5.0 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S64 PF08192.6 KFX92856.1 - 8.7 4.5 13.8 9.5 4.4 9.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 CDC27 PF09507.5 KFX92856.1 - 9 5.4 20.9 11 5.1 14.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF572 PF04502.8 KFX92856.1 - 9.2 5.3 15.1 11 5.1 10.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_TAF50 PF03326.8 KFX92856.1 - 9.7 5.0 17.6 12 4.6 12.2 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF3425 PF11905.3 KFX92857.1 - 4e-13 49.4 0.3 1.1e-12 47.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX92857.1 - 0.0001 22.2 14.1 0.00034 20.5 9.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX92857.1 - 0.97 9.3 16.8 45 3.9 11.6 2.2 1 1 0 1 1 1 0 Basic region leucine zipper p450 PF00067.17 KFX92858.1 - 5.9e-45 153.6 0.0 1.1e-44 152.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF4148 PF13663.1 KFX92858.1 - 0.12 12.2 0.1 0.4 10.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Zn_clus PF00172.13 KFX92860.1 - 8.1e-08 32.0 11.0 8.1e-08 32.0 7.6 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX92860.1 - 3.1e-07 29.3 8.4 5.7e-07 28.4 5.9 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tim17 PF02466.14 KFX92863.1 - 3.7e-07 30.2 1.9 8e-07 29.1 1.3 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Exo5 PF09810.4 KFX92867.1 - 3e-65 220.5 0.0 3.6e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KFX92867.1 - 0.0043 16.4 0.1 0.086 12.2 0.0 2.1 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily EamA PF00892.15 KFX92871.1 - 1.8e-06 27.9 11.1 1.8e-06 27.9 7.7 1.8 2 1 0 2 2 2 1 EamA-like transporter family DUF3392 PF11872.3 KFX92871.1 - 2.3 8.2 6.6 7.3 6.6 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3392) Sugar_tr PF00083.19 KFX92872.1 - 1.2e-73 248.2 30.8 1.4e-73 248.0 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX92872.1 - 9.5e-17 60.7 28.3 9.5e-17 60.7 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CMD PF02627.15 KFX92872.1 - 0.12 12.2 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family MFS_2 PF13347.1 KFX92872.1 - 1.1 7.5 32.2 0.49 8.7 7.3 3.0 2 2 1 3 3 3 0 MFS/sugar transport protein Peptidase_S9 PF00326.16 KFX92873.1 - 2e-15 56.5 0.0 2.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFX92873.1 - 1.8e-08 34.2 0.0 1.4e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX92873.1 - 2e-08 34.1 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX92873.1 - 3.3e-06 26.5 0.0 6e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KFX92873.1 - 0.00033 20.6 0.9 0.0055 16.6 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFX92873.1 - 0.0029 17.0 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2048 PF09752.4 KFX92873.1 - 0.0038 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Peptidase_S15 PF02129.13 KFX92873.1 - 0.062 12.7 0.0 0.46 9.8 0.0 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) GFO_IDH_MocA PF01408.17 KFX92875.1 - 2.5e-18 66.7 0.0 4.9e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX92875.1 - 6e-17 61.4 0.2 1.8e-16 59.9 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KFX92875.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ubiquitin PF00240.18 KFX92877.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family eIF-1a PF01176.14 KFX92877.1 - 0.073 12.5 0.4 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Rad60-SLD PF11976.3 KFX92877.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glyco_hydro_11 PF00457.12 KFX92878.1 - 7.7e-79 263.3 18.5 1e-78 262.8 12.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KFX92878.1 - 1.7e-09 37.1 16.7 6.8e-09 35.2 11.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX92878.1 - 0.46 10.5 9.5 1 9.4 6.6 1.6 1 1 0 1 1 1 0 Toxin 7 BTB PF00651.26 KFX92879.1 - 6.9e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Rhodanese PF00581.15 KFX92880.1 - 0.0014 18.9 0.1 0.004 17.5 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain cEGF PF12662.2 KFX92880.1 - 0.17 11.5 4.5 0.1 12.2 0.6 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like Peptidase_S24 PF00717.18 KFX92881.1 - 1.9e-08 33.8 0.0 2.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 KFX92882.1 - 4.3e-42 142.8 0.0 4.8e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX92882.1 - 8.2e-07 28.8 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFX92882.1 - 0.014 15.3 0.4 0.014 15.3 0.3 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KFX92882.1 - 0.074 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain TRAM_LAG1_CLN8 PF03798.11 KFX92883.1 - 3.2e-40 137.8 18.0 3.2e-40 137.8 12.5 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KFX92883.1 - 2.7e-18 65.1 0.1 2.7e-18 65.1 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein DUF4512 PF14975.1 KFX92883.1 - 0.086 13.6 0.0 0.68 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) TRAM_LAG1_CLN8 PF03798.11 KFX92884.1 - 9.3e-32 110.1 24.6 1.4e-31 109.6 17.0 1.3 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.20 KFX92884.1 - 1.3e-31 109.7 0.0 3e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain TRAM1 PF08390.6 KFX92884.1 - 2.3e-23 81.4 0.1 6.6e-23 79.9 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein Pkinase_Tyr PF07714.12 KFX92884.1 - 1.6e-06 27.4 0.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glycos_transf_1 PF00534.15 KFX92885.1 - 3.4e-17 62.3 0.0 7.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX92885.1 - 1.8e-07 31.3 0.0 2.4e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KFX92885.1 - 0.099 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-Tim10_DDP PF02953.10 KFX92892.1 - 4.2e-21 73.9 1.9 5.8e-21 73.5 1.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RhoGAP PF00620.22 KFX92893.1 - 7.9e-40 135.9 0.0 1.2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 KFX92893.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family DUF605 PF04652.11 KFX92894.1 - 0.014 14.8 17.2 0.014 14.8 11.9 1.2 1 0 0 1 1 1 0 Vta1 like PAP_assoc PF03828.14 KFX92896.1 - 4.2e-12 45.8 0.0 9.5e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFX92896.1 - 0.00017 21.8 0.0 0.00092 19.5 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain RGS-like PF09128.6 KFX92896.1 - 0.006 16.0 0.2 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain TFIIF_alpha PF05793.7 KFX92897.1 - 2e-13 49.6 46.8 3.3e-13 48.8 29.5 2.5 1 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med24_N PF11277.3 KFX92898.1 - 0.14 9.6 0.8 0.17 9.3 0.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Arrestin_C PF02752.17 KFX92901.1 - 2e-13 50.5 0.1 1.1e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pol_alpha_B_N PF08418.5 KFX92905.1 - 4.9e-60 203.1 0.3 6.8e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KFX92905.1 - 1.7e-36 125.4 0.0 2.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 KFX92906.1 - 2e-39 134.6 0.0 2.7e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX92906.1 - 1.6e-07 31.2 0.0 3.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFX92906.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TRAPP PF04051.11 KFX92907.1 - 7.7e-38 129.3 0.0 9.2e-38 129.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.6 KFX92908.1 - 2.8e-32 110.5 0.3 3.2e-32 110.3 0.2 1.0 1 0 0 1 1 1 1 Apc13p protein zf-RING_2 PF13639.1 KFX92909.1 - 1.2e-06 28.2 6.3 1.2e-06 28.2 2.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KFX92909.1 - 0.00076 19.5 0.7 0.0019 18.2 0.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX92909.1 - 0.0035 17.3 2.9 0.0035 17.3 2.0 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX92909.1 - 0.0083 15.7 2.2 0.028 14.0 1.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4279 PF14106.1 KFX92909.1 - 0.034 14.0 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) zf-RING_5 PF14634.1 KFX92909.1 - 0.067 12.9 3.3 0.33 10.7 2.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-Apc11 PF12861.2 KFX92909.1 - 0.16 11.7 1.4 1.9 8.4 1.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KFX92909.1 - 0.22 11.5 5.1 0.31 11.1 2.7 2.0 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 KFX92909.1 - 0.87 9.5 6.7 31 4.6 0.0 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KFX92909.1 - 1.1 9.2 7.9 3.2 7.7 3.3 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFX92909.1 - 6.5 6.5 13.9 0.99 9.1 4.8 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Kinesin PF00225.18 KFX92910.1 - 8.5e-112 373.1 0.0 8.5e-112 373.1 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain DUF87 PF01935.12 KFX92910.1 - 0.63 9.8 0.0 0.63 9.8 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF87 PUL PF08324.6 KFX92911.1 - 3.1e-37 127.8 0.1 5e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KFX92911.1 - 1e-32 113.0 0.0 1.6e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KFX92911.1 - 1.6e-13 50.1 0.0 3.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFX92911.1 - 0.00032 20.8 1.0 0.0039 17.3 0.7 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 KFX92911.1 - 0.00087 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.1 KFX92911.1 - 0.15 12.2 0.1 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like GDA1_CD39 PF01150.12 KFX92912.1 - 1.6e-92 310.3 0.0 2.1e-92 309.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family VHS PF00790.14 KFX92914.1 - 4.7e-38 129.9 0.8 6.9e-37 126.2 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KFX92914.1 - 6.7e-16 57.9 2.8 1.3e-15 56.9 1.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KFX92914.1 - 0.00011 21.4 10.4 0.029 13.9 0.6 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KFX92914.1 - 0.04 13.3 0.6 0.13 11.6 0.4 1.8 1 0 0 1 1 1 0 DHHC palmitoyltransferase NUDIX PF00293.23 KFX92915.1 - 9.3e-15 54.4 0.2 2.6e-14 53.0 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain Glyco_hydro_75 PF07335.6 KFX92917.1 - 1.4e-36 125.7 0.2 2e-36 125.2 0.1 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CarbpepA_inh PF02977.10 KFX92917.1 - 0.096 12.2 25.6 3 7.4 7.9 3.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Phage_tail_T PF06223.7 KFX92919.1 - 0.035 14.5 3.0 0.7 10.3 0.4 2.5 1 1 1 2 2 2 0 Minor tail protein T UPF0016 PF01169.14 KFX92919.1 - 2.8 8.1 14.8 3.6 7.7 4.3 2.8 1 1 0 2 2 2 0 Uncharacterized protein family UPF0016 BBP1_C PF15272.1 KFX92920.1 - 0.0067 16.0 0.1 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Acyl-CoA_dh_1 PF00441.19 KFX92921.1 - 2.6e-43 147.7 1.4 2.6e-43 147.7 1.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX92921.1 - 6.2e-31 107.2 0.1 1.7e-30 105.8 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFX92921.1 - 1.4e-20 72.4 0.2 3.1e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX92921.1 - 1e-15 58.1 0.2 2.4e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KFX92921.1 - 0.017 14.5 0.4 0.084 12.2 0.3 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 KFX92922.1 - 5.2e-142 473.6 0.1 6.8e-142 473.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Bot1p PF12298.3 KFX92923.1 - 1.1e-52 178.4 1.2 1.5e-52 177.9 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein E1-E2_ATPase PF00122.15 KFX92924.1 - 2.3e-64 216.5 2.5 2.3e-64 216.5 1.7 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX92924.1 - 1.9e-32 112.2 9.4 1.9e-32 112.2 6.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX92924.1 - 1.2e-29 104.2 0.1 3.5e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX92924.1 - 4.5e-17 61.7 0.0 1.8e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFX92924.1 - 3.5e-15 55.2 0.0 9.3e-15 53.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFX92924.1 - 9.7e-14 51.9 0.0 2.1e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX92924.1 - 0.00042 19.9 0.6 0.001 18.7 0.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ytp1 PF10355.4 KFX92925.1 - 1.9e-91 306.0 11.6 3.6e-91 305.1 8.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFX92925.1 - 3.7e-26 90.7 8.2 6.9e-25 86.6 1.5 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) Zn_clus PF00172.13 KFX92925.1 - 4.5e-08 32.8 15.3 8.1e-08 32.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RicinB_lectin_2 PF14200.1 KFX92926.1 - 0.079 13.3 0.0 3.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like LNS2 PF08235.8 KFX92934.1 - 5.3e-70 234.0 0.0 8.7e-70 233.3 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFX92934.1 - 1.1e-40 137.7 0.0 2.4e-40 136.6 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KFX92934.1 - 0.092 12.1 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 KFX92934.1 - 0.18 11.7 5.6 0.85 9.5 3.9 2.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Peptidase_M49 PF03571.10 KFX92935.1 - 6.6e-199 661.5 0.0 8.4e-199 661.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.15 KFX92935.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HATPase_c_2 PF13581.1 KFX92936.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain 4HBT_3 PF13622.1 KFX92938.1 - 2.7e-33 115.7 0.0 4.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 KFX92938.1 - 1.5e-31 109.4 29.0 1.5e-31 109.4 20.1 1.9 3 0 0 3 3 3 1 Major Facilitator Superfamily 4HBT PF03061.17 KFX92938.1 - 0.00085 19.3 0.0 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 Thioesterase superfamily Zn_clus PF00172.13 KFX92939.1 - 1.3e-06 28.1 8.5 2.6e-06 27.2 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.1 KFX92940.1 - 7.5e-50 169.3 0.4 9e-50 169.1 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFX92940.1 - 2.5e-21 75.5 0.2 3.4e-21 75.0 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Harakiri PF15196.1 KFX92940.1 - 0.092 13.0 0.3 0.34 11.1 0.1 2.0 2 0 0 2 2 2 0 Activator of apoptosis harakiri DUF3359 PF11839.3 KFX92942.1 - 4.6 7.6 10.0 6.5 7.1 5.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) RNA_pol_Rpb1_1 PF04997.7 KFX92943.1 - 1.2e-109 366.6 0.0 2.3e-109 365.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KFX92943.1 - 1.7e-105 352.2 0.1 2.5e-105 351.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFX92943.1 - 2.5e-71 238.9 0.0 5.3e-71 237.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KFX92943.1 - 7.2e-59 198.6 6.0 1.7e-58 197.4 4.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KFX92943.1 - 1.8e-48 164.2 0.0 4.8e-48 162.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KFX92943.1 - 8e-44 148.6 5.8 2.4e-43 147.0 4.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KFX92943.1 - 1.6e-37 127.5 0.1 3.7e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KFX92943.1 - 4.7e-06 26.2 176.4 0.11 12.6 4.4 13.2 14 0 0 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat Pirin PF02678.11 KFX92944.1 - 1.6e-22 79.3 1.1 4.7e-22 77.8 0.8 1.8 1 1 0 1 1 1 1 Pirin ADH_N PF08240.7 KFX92944.1 - 6.1e-11 42.0 0.2 5.1e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX92944.1 - 3.9e-07 30.9 0.0 1.1e-06 29.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 KFX92944.1 - 1.7e-05 24.2 4.0 6.7e-05 22.3 0.5 3.1 2 1 0 2 2 2 1 Cupin domain ADH_zinc_N PF00107.21 KFX92944.1 - 0.0028 17.2 0.1 0.0068 15.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hemerythrin PF01814.18 KFX92945.1 - 5.7e-11 42.6 0.1 8.9e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Lactonase PF10282.4 KFX92946.1 - 1.8e-06 27.2 0.0 0.00016 20.9 0.0 2.8 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller bZIP_1 PF00170.16 KFX92947.1 - 0.00024 20.9 6.3 0.00024 20.9 4.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor LURAP PF14854.1 KFX92947.1 - 0.085 12.5 1.2 0.12 12.1 0.2 1.7 2 0 0 2 2 2 0 Leucine rich adaptor protein Annexin PF00191.15 KFX92948.1 - 2.6e-19 68.8 3.4 0.00013 21.8 0.0 4.4 4 0 0 4 4 4 4 Annexin GPI2 PF06432.6 KFX92949.1 - 2.4e-120 401.1 0.3 2.8e-120 400.8 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3136 PF11334.3 KFX92949.1 - 0.024 14.0 0.3 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Pyr_redox_3 PF13738.1 KFX92950.1 - 5.4e-24 85.3 0.0 1.3e-23 84.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX92950.1 - 1e-16 60.2 0.3 8e-16 57.3 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFX92950.1 - 8e-12 44.7 0.5 1.9e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX92950.1 - 5.1e-07 29.7 0.0 0.00022 21.1 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX92950.1 - 1.1e-06 28.5 0.0 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KFX92950.1 - 8e-05 22.7 0.1 0.07 13.2 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KFX92950.1 - 0.00043 19.2 0.0 0.0072 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX92950.1 - 0.012 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KFX92950.1 - 0.052 12.6 1.1 0.086 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 KFX92950.1 - 0.093 12.4 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KFX92950.1 - 0.1 11.0 0.4 0.22 9.9 0.3 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KFX92950.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_4 PF01565.18 KFX92951.1 - 2.5e-19 69.1 2.4 3.2e-19 68.7 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain p450 PF00067.17 KFX92952.1 - 1.4e-19 70.0 0.0 7.5e-15 54.3 0.0 2.9 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_7 PF00840.15 KFX92953.1 - 3.8e-202 671.3 16.0 7.4e-202 670.4 11.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pec_lyase_C PF00544.14 KFX92953.1 - 1.7e-20 73.3 1.2 3e-20 72.5 0.8 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFX92953.1 - 7.6e-05 22.5 10.6 0.00049 19.8 6.9 2.6 1 1 1 2 2 2 2 Right handed beta helix region Cu-oxidase_3 PF07732.10 KFX92954.1 - 6.4e-12 45.2 0.0 9e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX92954.1 - 1.4e-06 27.8 0.0 0.072 12.6 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KFX92954.1 - 0.02 14.7 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 Cupredoxin-like domain Copper-bind PF00127.15 KFX92954.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family SGL PF08450.7 KFX92955.1 - 8.8e-06 25.2 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Abhydrolase_3 PF07859.8 KFX92956.1 - 2.8e-35 121.8 0.1 4.7e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX92956.1 - 1.5e-06 28.0 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX92956.1 - 4e-06 25.8 0.0 5.9e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFX92956.1 - 0.00077 18.7 0.1 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 KFX92956.1 - 0.002 16.6 0.0 0.0033 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 KFX92956.1 - 0.0021 17.4 0.1 0.051 12.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFX92956.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFX92956.1 - 0.017 15.0 2.4 0.042 13.7 1.7 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KFX92956.1 - 0.034 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BNR PF02012.15 KFX92957.1 - 3e-11 41.3 37.3 0.28 11.1 0.4 9.7 9 0 0 9 9 9 8 BNR/Asp-box repeat Glyco_hydro_2_N PF02837.13 KFX92958.1 - 1.7e-33 115.5 0.0 4.8e-33 114.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFX92958.1 - 6.8e-28 97.4 0.0 2.5e-27 95.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFX92958.1 - 3.4e-12 46.7 0.2 7.3e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFX92958.1 - 0.0034 17.6 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain fn3 PF00041.16 KFX92959.1 - 5.9e-08 32.7 0.0 1.9e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain DAO PF01266.19 KFX92966.1 - 2.6e-50 171.3 0.0 4.4e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase PPR_2 PF13041.1 KFX92966.1 - 6.8e-19 67.5 0.3 1.4e-08 34.5 0.0 6.0 4 2 2 6 6 6 3 PPR repeat family PPR PF01535.15 KFX92966.1 - 1.3e-10 40.5 0.0 0.0085 16.0 0.0 5.1 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 KFX92966.1 - 9.5e-10 37.9 0.2 0.00066 19.7 0.0 4.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain FAD_binding_2 PF00890.19 KFX92966.1 - 1.9e-08 33.5 0.2 5.2e-08 32.1 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain PPR_1 PF12854.2 KFX92966.1 - 8e-08 31.6 0.0 0.068 12.6 0.0 4.6 4 0 0 4 4 4 2 PPR repeat FAD_oxidored PF12831.2 KFX92966.1 - 1.6e-05 24.2 3.5 0.00013 21.2 2.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX92966.1 - 0.0002 21.2 0.1 0.00079 19.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX92966.1 - 0.0051 16.8 0.1 0.013 15.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX92966.1 - 0.018 15.4 0.4 0.056 13.8 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX92966.1 - 0.043 12.2 0.2 0.072 11.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFX92966.1 - 0.07 12.7 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KFX92966.1 - 0.2 10.7 0.2 0.51 9.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 KFX92966.1 - 0.23 10.2 0.5 0.67 8.7 0.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A cwf18 PF08315.7 KFX92967.1 - 1.6e-43 148.2 4.9 1.6e-43 148.2 3.4 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor DUF3585 PF12130.3 KFX92967.1 - 0.023 14.5 1.5 0.023 14.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) zf-CCHC_3 PF13917.1 KFX92968.1 - 1.7e-20 72.4 1.6 4.1e-20 71.2 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KFX92968.1 - 0.00081 18.8 0.3 0.0018 17.7 0.2 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 KFX92968.1 - 0.0046 16.8 1.3 0.0074 16.1 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KFX92968.1 - 0.13 11.7 0.6 0.34 10.4 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle SUZ PF12752.2 KFX92969.1 - 3.4e-17 62.6 1.3 3.4e-17 62.6 0.9 2.6 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 KFX92969.1 - 5.5e-09 35.5 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.14 KFX92970.1 - 1.1e-32 112.4 0.0 2.2e-32 111.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 DUF3552 PF12072.3 KFX92970.1 - 0.54 9.4 3.8 0.93 8.6 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) DUF1964 PF09244.5 KFX92971.1 - 0.17 12.2 0.3 47 4.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1964) DUF3253 PF11625.3 KFX92971.1 - 1.5 8.7 6.4 17 5.4 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3253) DUF1253 PF06862.7 KFX92972.1 - 1.5e-167 557.5 0.0 1.8e-167 557.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 KFX92972.1 - 6.8e-05 22.4 0.0 0.0026 17.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3347 PF11827.3 KFX92972.1 - 0.41 10.6 7.6 5.7 6.9 4.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) DUF2146 PF10220.4 KFX92972.1 - 6.4 4.6 10.7 10 3.9 7.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) JAB PF01398.16 KFX92973.1 - 6.8e-17 61.2 0.0 1.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFX92973.1 - 8.8e-15 54.7 0.1 1.4e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3113 PF11310.3 KFX92973.1 - 0.041 13.5 0.1 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) FoP_duplication PF13865.1 KFX92973.1 - 5 7.6 15.4 8.3 6.9 10.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosom_S12_S23 PF00164.20 KFX92975.1 - 9.3e-40 134.8 0.1 1.2e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2365 PF10157.4 KFX92976.1 - 0.062 13.1 0.1 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF1242 PF06842.7 KFX92977.1 - 9.2e-18 63.4 0.1 1.7e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.11 KFX92978.1 - 6e-18 64.4 0.0 1.7e-17 63.0 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit BTB PF00651.26 KFX92978.1 - 3.8e-08 33.2 0.0 1.3e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Bromo_TP PF07524.8 KFX92978.1 - 0.022 14.4 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated DUF3227 PF11537.3 KFX92978.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) 4HBT_2 PF13279.1 KFX92981.1 - 3.2e-07 30.8 0.0 3.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 KFX92991.1 - 4.8e-42 143.9 55.7 4.9e-42 143.9 36.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX92991.1 - 1.8e-15 56.1 20.2 3.2e-15 55.3 14.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 KFX92992.1 - 5.7e-56 184.5 12.5 1.2e-12 47.1 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 KFX92992.1 - 1.8e-13 49.7 0.4 1.9 8.2 0.0 7.4 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFX92992.1 - 3.2e-10 40.0 0.0 1.6e-05 24.6 0.0 3.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KFX92992.1 - 4.9e-08 32.1 3.3 4.6 6.6 0.0 7.7 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature Nup160 PF11715.3 KFX92992.1 - 0.00052 18.2 1.9 0.028 12.5 0.2 3.2 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFX92992.1 - 0.0006 19.0 2.4 2.4 7.1 0.0 5.2 2 2 5 7 7 7 1 Neuroblastoma-amplified sequence, N terminal Zn_clus PF00172.13 KFX92992.1 - 0.0032 17.3 15.1 0.0064 16.3 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPPIV_N PF00930.16 KFX92992.1 - 0.0071 14.9 0.0 0.76 8.2 0.0 3.2 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.6 KFX92992.1 - 0.018 14.7 1.0 92 2.7 0.0 5.5 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal Gmad1 PF10647.4 KFX92992.1 - 0.043 13.2 0.1 7 5.9 0.0 3.1 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 KFX92992.1 - 0.075 11.3 0.0 2.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Beta-lactamase PF00144.19 KFX92993.1 - 1.1e-43 149.5 0.0 1.6e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase NACHT PF05729.7 KFX92997.1 - 6e-09 35.7 0.6 2.8e-08 33.5 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFX92997.1 - 1e-05 25.7 0.1 6.2e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX92997.1 - 0.002 17.6 1.2 0.0097 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KFX92997.1 - 0.0024 18.1 0.6 0.019 15.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KFX92997.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Miro PF08477.8 KFX92997.1 - 0.032 14.7 0.0 2.6 8.5 0.0 3.7 4 0 0 4 4 4 0 Miro-like protein MMR_HSR1 PF01926.18 KFX92997.1 - 0.036 14.0 0.0 0.33 10.9 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KFX92997.1 - 0.045 13.2 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX92997.1 - 0.051 14.3 3.3 0.088 13.6 0.2 3.0 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.1 KFX92997.1 - 0.055 13.4 0.0 0.055 13.4 0.0 3.3 3 2 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 KFX92997.1 - 0.56 10.5 0.0 0.56 10.5 0.0 3.2 3 1 0 3 3 3 0 ABC transporter bZIP_1 PF00170.16 KFX93014.1 - 1.6e-09 37.5 2.1 1.6e-09 37.5 1.4 3.1 3 0 0 3 3 3 1 bZIP transcription factor SAM_2 PF07647.12 KFX93014.1 - 2.7e-09 36.7 0.0 6.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFX93014.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_2 PF07716.10 KFX93014.1 - 0.0046 16.7 6.0 0.0046 16.7 4.1 3.1 3 0 0 3 3 3 1 Basic region leucine zipper zf-C2H2_4 PF13894.1 KFX93014.1 - 1.6 9.2 12.8 6.9 7.2 1.3 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF846 PF05832.7 KFX93015.1 - 1.5e-51 173.8 13.4 1.7e-51 173.6 9.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Med14 PF08638.6 KFX93018.1 - 1.7e-67 226.4 0.0 2.8e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.3 KFX93019.1 - 6.4e-191 634.9 17.9 7.3e-191 634.7 12.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KFX93019.1 - 4.5e-05 22.3 18.1 4.5e-05 22.3 12.6 3.2 2 2 1 3 3 3 3 Major Facilitator Superfamily Pex24p PF06398.6 KFX93019.1 - 1.5 7.5 10.1 2.6 6.7 4.8 2.5 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Fungal_trans PF04082.13 KFX93036.1 - 2.5e-44 151.1 0.1 5.5e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93036.1 - 1.1e-08 34.8 8.1 2.2e-08 33.8 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 KFX93037.1 - 1.6e-28 99.7 0.7 2.3e-28 99.2 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) INCENP_N PF12178.3 KFX93037.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal Nipped-B_C PF12830.2 KFX93038.1 - 3.1e-45 154.1 7.4 3.2e-45 154.0 1.9 3.2 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KFX93038.1 - 1.2e-08 34.7 2.3 2.8e-08 33.5 0.3 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KFX93038.1 - 0.13 12.4 6.5 16 5.8 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat TFIIS_C PF01096.13 KFX93039.1 - 4e-14 51.9 1.9 4e-14 51.9 1.3 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFX93039.1 - 9e-05 22.0 2.5 9e-05 22.0 1.8 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 KFX93039.1 - 0.00065 19.0 9.7 1.9 8.0 0.0 4.1 4 0 0 4 4 4 2 zinc-ribbon domain IBR PF01485.16 KFX93039.1 - 0.042 13.7 9.0 0.19 11.6 0.4 2.4 2 1 0 2 2 2 0 IBR domain RecR PF02132.10 KFX93039.1 - 0.068 12.6 5.6 0.087 12.2 1.7 2.3 2 0 0 2 2 2 0 RecR protein Ogr_Delta PF04606.7 KFX93039.1 - 0.094 12.3 0.6 0.094 12.3 0.4 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DUF2072 PF09845.4 KFX93039.1 - 0.12 12.2 5.8 1.5 8.7 1.0 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-ribbon_3 PF13248.1 KFX93039.1 - 0.17 11.1 0.2 0.17 11.1 0.1 3.7 3 1 1 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KFX93039.1 - 0.18 11.4 13.4 0.97 9.1 1.5 2.9 2 2 0 2 2 2 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.4 KFX93039.1 - 0.21 10.6 2.7 1.4 7.9 0.6 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Lar_restr_allev PF14354.1 KFX93039.1 - 0.25 11.6 10.6 0.89 9.9 0.4 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar DUF164 PF02591.10 KFX93039.1 - 0.26 11.1 4.4 2 8.3 0.1 2.9 3 0 0 3 3 3 0 Putative zinc ribbon domain RRN7 PF11781.3 KFX93039.1 - 0.34 10.4 12.3 0.76 9.3 0.3 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KFX93039.1 - 0.43 10.4 14.0 3.3 7.5 6.1 2.9 1 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KFX93039.1 - 0.66 9.5 7.3 14 5.2 0.0 3.2 2 1 1 3 3 3 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.5 KFX93039.1 - 0.71 9.8 0.1 0.71 9.8 0.1 3.2 3 1 0 3 3 3 0 Zinc ribbon domain HypA PF01155.14 KFX93039.1 - 1.1 8.9 9.0 3.2 7.4 0.7 2.4 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 KFX93039.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-IS66 PF13005.2 KFX93039.1 - 2.2 8.3 11.2 15 5.6 0.3 3.9 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-ISL3 PF14690.1 KFX93039.1 - 4.4 7.4 6.1 8.6 6.4 0.0 3.2 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 KFX93039.1 - 4.5 6.6 18.4 1.3 8.3 0.2 3.7 2 2 1 3 3 3 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 KFX93039.1 - 7.6 6.8 13.3 12 6.2 0.1 3.3 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-RING_3 PF14369.1 KFX93039.1 - 9.5 6.3 7.5 1.4 8.9 0.1 2.6 2 1 0 2 2 2 0 zinc-finger HEAT_2 PF13646.1 KFX93040.1 - 2e-32 111.3 10.1 9.4e-17 61.0 0.1 3.5 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 KFX93040.1 - 5.3e-20 69.8 6.6 0.00075 19.7 0.1 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KFX93040.1 - 1.6e-07 31.6 10.5 0.00038 20.8 0.4 4.7 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.17 KFX93040.1 - 5.7e-06 25.9 6.6 0.086 12.9 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HrpB1_HrpK PF09613.5 KFX93040.1 - 0.02 14.3 3.6 0.03 13.8 0.8 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Cohesin_HEAT PF12765.2 KFX93040.1 - 0.047 13.6 0.8 0.75 9.8 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ABC_tran PF00005.22 KFX93041.1 - 1.7e-47 161.1 0.1 2.9e-23 82.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX93041.1 - 4.6e-18 65.2 0.0 5e-06 25.8 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX93041.1 - 1.1e-17 64.8 0.6 0.00064 19.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KFX93041.1 - 1.3e-09 37.4 0.1 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX93041.1 - 2.7e-08 34.6 0.0 0.0031 18.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX93041.1 - 3.1e-08 32.9 0.1 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX93041.1 - 5e-08 33.5 7.5 0.0011 19.3 0.9 3.3 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KFX93041.1 - 9.3e-08 32.2 0.1 0.00085 19.4 0.0 3.5 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.18 KFX93041.1 - 1.4e-07 31.4 0.0 0.0027 17.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 KFX93041.1 - 1.5e-07 30.8 0.6 0.23 10.4 0.0 4.0 3 1 1 4 4 4 3 AAA ATPase domain AAA_28 PF13521.1 KFX93041.1 - 5.3e-07 29.7 0.0 0.0087 16.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KFX93041.1 - 8.1e-07 29.0 0.1 0.00041 20.2 0.0 3.0 3 0 0 3 3 2 1 Dynamin family AAA_33 PF13671.1 KFX93041.1 - 2e-06 27.7 0.2 0.088 12.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KFX93041.1 - 6.3e-06 25.8 0.1 0.25 10.7 0.0 3.5 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 KFX93041.1 - 1.1e-05 25.8 0.0 0.062 13.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 KFX93041.1 - 1.4e-05 25.3 0.2 0.27 11.5 0.0 3.5 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KFX93041.1 - 2.2e-05 24.2 0.0 0.31 10.7 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KFX93041.1 - 3.1e-05 23.8 0.0 0.14 12.1 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 KFX93041.1 - 3.1e-05 22.8 0.1 0.2 10.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 KFX93041.1 - 5e-05 23.4 0.0 0.7 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 KFX93041.1 - 6.8e-05 23.0 0.0 0.38 10.9 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX93041.1 - 0.00017 21.5 0.3 1.1 9.2 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.7 KFX93041.1 - 0.00023 20.8 0.1 0.09 12.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KFX93041.1 - 0.00031 20.5 0.0 0.85 9.2 0.0 3.2 3 0 0 3 3 2 2 Archaeal ATPase AAA_14 PF13173.1 KFX93041.1 - 0.00042 20.2 0.0 1.1 9.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain PduV-EutP PF10662.4 KFX93041.1 - 0.00055 19.4 0.0 0.88 9.0 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFX93041.1 - 0.0017 17.8 0.5 1.3 8.4 0.0 3.3 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 KFX93041.1 - 0.0024 17.7 2.0 1 9.1 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KFX93041.1 - 0.0044 16.5 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KFX93041.1 - 0.0047 16.5 0.0 5.6 6.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.16 KFX93041.1 - 0.0049 16.3 0.0 0.73 9.1 0.0 2.5 2 0 0 2 2 2 1 MutS domain V AAA_25 PF13481.1 KFX93041.1 - 0.0078 15.6 0.0 6.1 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KFX93041.1 - 0.0099 14.3 12.5 0.87 7.9 0.0 4.6 4 1 0 5 5 5 1 AAA domain ATP_bind_1 PF03029.12 KFX93041.1 - 0.025 14.1 0.2 7.8 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KFX93041.1 - 0.026 13.9 0.1 3.1 7.2 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 KFX93041.1 - 0.028 13.4 0.2 2.9 6.8 0.0 2.7 3 0 0 3 3 2 0 Septin Mg_chelatase PF01078.16 KFX93041.1 - 0.03 13.4 0.0 2.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 KFX93041.1 - 0.033 13.7 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 KFX93041.1 - 0.038 12.6 0.0 3.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KFX93041.1 - 0.06 13.0 0.0 16 5.1 0.0 2.8 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 KFX93041.1 - 0.063 12.1 2.3 4.9 5.9 0.0 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein HEAT PF02985.17 KFX93041.1 - 0.083 13.0 0.6 14 6.0 0.0 3.8 4 0 0 4 4 2 0 HEAT repeat V-ATPase_H_C PF11698.3 KFX93041.1 - 0.09 12.7 1.7 0.26 11.2 1.2 1.8 1 0 0 1 1 1 0 V-ATPase subunit H NB-ARC PF00931.17 KFX93041.1 - 0.096 11.5 1.5 0.46 9.2 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain DAP3 PF10236.4 KFX93041.1 - 1.5 7.6 6.7 11 4.8 0.8 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 RTA1 PF04479.8 KFX93044.1 - 1.9e-16 60.2 3.8 2.9e-16 59.6 2.0 1.7 1 1 0 1 1 1 1 RTA1 like protein PAP2_C PF14360.1 KFX93044.1 - 0.062 13.5 2.5 0.27 11.5 1.7 2.2 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Arginase PF00491.16 KFX93045.1 - 8.6e-73 245.0 1.0 9.8e-73 244.8 0.7 1.0 1 0 0 1 1 1 1 Arginase family MORN PF02493.15 KFX93046.1 - 1.1 9.1 3.8 2.7 7.8 0.2 2.7 3 0 0 3 3 3 0 MORN repeat Gag_spuma PF03276.9 KFX93056.1 - 2.5 6.3 5.9 3.8 5.7 4.1 1.3 1 0 0 1 1 1 0 Spumavirus gag protein HCO3_cotransp PF00955.16 KFX93058.1 - 2.9e-53 181.2 15.3 8e-33 113.8 5.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF948 PF06103.6 KFX93059.1 - 0.059 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Sipho_Gp157 PF05565.6 KFX93059.1 - 0.1 12.2 1.2 0.24 10.9 0.8 1.6 1 0 0 1 1 1 0 Siphovirus Gp157 DUF948 PF06103.6 KFX93074.1 - 0.047 13.5 0.1 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PMEI PF04043.10 KFX93074.1 - 0.075 12.9 3.4 0.39 10.5 0.0 2.7 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Cep57_CLD_2 PF14197.1 KFX93074.1 - 1.3 9.0 7.1 3.2 7.7 0.8 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Metallophos PF00149.23 KFX93078.1 - 5e-11 42.3 0.0 8.1e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX93078.1 - 3.4e-07 30.2 0.1 6e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Isy1 PF06246.7 KFX93079.1 - 1.3e-69 234.4 0.9 1.8e-69 233.9 0.6 1.2 1 0 0 1 1 1 1 Isy1-like splicing family Methyltransf_2 PF00891.13 KFX93081.1 - 7.5e-35 120.2 0.0 1.1e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFX93081.1 - 0.00013 22.5 0.0 0.00044 20.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX93081.1 - 0.0055 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KFX93081.1 - 0.041 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Abhydrolase_6 PF12697.2 KFX93082.1 - 6.4e-31 107.9 3.0 2.5e-30 106.0 2.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.23 KFX93082.1 - 2.4e-17 62.8 0.1 6.5e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Abhydrolase_1 PF00561.15 KFX93082.1 - 2.8e-15 56.5 0.2 7.5e-15 55.1 0.2 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX93082.1 - 3.1e-12 46.4 0.0 2.9e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX93082.1 - 9.6e-10 38.1 0.0 2.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KFX93082.1 - 0.031 13.7 0.0 5 6.4 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Sugar_tr PF00083.19 KFX93083.1 - 7.4e-106 354.4 20.4 8.9e-106 354.1 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93083.1 - 7.5e-24 84.0 27.2 2.1e-15 56.3 4.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ACT_3 PF10000.4 KFX93084.1 - 6.9e-18 64.1 0.3 1.3e-16 60.0 0.2 2.3 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.1 KFX93084.1 - 1.5e-12 46.8 0.1 3.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain WW PF00397.21 KFX93085.1 - 0.077 12.8 2.6 0.19 11.6 1.8 1.6 1 0 0 1 1 1 0 WW domain Abhydrolase_1 PF00561.15 KFX93090.1 - 5e-16 58.9 0.1 7.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX93090.1 - 5.2e-08 33.0 0.0 9.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFX93090.1 - 7.1e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Exo70 PF03081.10 KFX93101.1 - 6.6e-66 222.5 0.0 1e-65 221.9 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Reticulon PF02453.12 KFX93102.1 - 1.5e-36 125.5 0.9 2.1e-36 125.0 0.6 1.2 1 0 0 1 1 1 1 Reticulon Aminotran_1_2 PF00155.16 KFX93103.1 - 4.9e-44 150.7 0.0 5.4e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KFX93103.1 - 0.027 13.1 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.15 KFX93103.1 - 0.11 10.7 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GATA PF00320.22 KFX93106.1 - 4.7e-17 61.0 2.8 1.8e-16 59.1 1.5 2.3 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 KFX93106.1 - 4e-14 51.8 4.6 7.9e-14 50.9 3.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SRF-TF PF00319.13 KFX93108.1 - 3e-23 80.8 0.3 4.2e-23 80.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 KFX93108.1 - 0.015 14.5 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.9 KFX93108.1 - 0.18 9.8 0.1 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.2 KFX93111.1 - 1.6e-10 40.5 0.3 4e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX93111.1 - 0.00019 20.9 0.4 0.0006 19.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KFX93111.1 - 0.1 12.2 4.3 0.67 9.6 0.3 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_3 PF00933.16 KFX93115.1 - 1.4e-87 293.4 0.0 2.1e-87 292.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX93115.1 - 2.9e-61 206.9 0.4 5.6e-61 205.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_88 PF07470.8 KFX93115.1 - 2.9e-28 98.8 0.0 5e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fn3-like PF14310.1 KFX93115.1 - 3.7e-27 94.0 0.1 6.9e-27 93.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Toxin_8 PF07365.7 KFX93115.1 - 0.75 9.8 6.2 1.6 8.7 1.0 2.7 2 0 0 2 2 2 0 Alpha conotoxin precursor SCO1-SenC PF02630.9 KFX93116.1 - 3.1e-60 202.7 0.0 5.7e-60 201.8 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KFX93116.1 - 3.3e-05 23.5 0.0 0.00025 20.6 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KFX93116.1 - 0.025 14.7 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like HemY_N PF07219.8 KFX93116.1 - 0.28 10.7 5.7 0.66 9.5 0.6 2.9 2 0 0 2 2 2 0 HemY protein N-terminus Plasmodium_Vir PF05795.6 KFX93116.1 - 0.36 9.9 0.1 11 5.0 0.0 2.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SIP1 PF04938.7 KFX93118.1 - 2.1e-05 23.9 0.0 0.00014 21.2 0.0 2.3 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Radical_SAM PF04055.16 KFX93119.1 - 2.7e-13 50.4 0.0 5.1e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily zf-RING_2 PF13639.1 KFX93127.1 - 9.6e-12 44.5 3.5 2e-11 43.5 2.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX93127.1 - 2.9e-11 43.2 0.5 5.6e-11 42.3 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFX93127.1 - 4.1e-06 26.5 0.5 7.8e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KFX93127.1 - 1.7e-05 24.3 1.6 3e-05 23.5 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX93127.1 - 1.9e-05 24.2 3.6 3.2e-05 23.5 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX93127.1 - 8e-05 22.2 4.2 0.00014 21.4 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX93127.1 - 0.00013 21.9 4.8 0.00028 20.8 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFX93127.1 - 0.0027 17.6 5.7 0.045 13.7 4.0 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KFX93127.1 - 0.0031 17.2 2.5 0.0066 16.1 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 KFX93127.1 - 0.056 12.9 1.4 0.14 11.6 0.9 1.6 1 0 0 1 1 1 0 P-11 zinc finger KAR9 PF08580.5 KFX93127.1 - 10 4.2 19.3 0.011 14.1 3.1 2.1 2 0 0 2 2 2 0 Yeast cortical protein KAR9 Inhibitor_I9 PF05922.11 KFX93130.1 - 0.00013 22.4 0.1 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 VHS PF00790.14 KFX93131.1 - 2.3e-05 24.0 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain CTD_bind PF04818.8 KFX93131.1 - 0.00047 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 KFX93131.1 - 0.016 15.3 1.5 0.056 13.5 1.0 1.9 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-RING_2 PF13639.1 KFX93131.1 - 0.12 12.2 0.9 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Ring finger domain zf-C2H2_4 PF13894.1 KFX93131.1 - 0.86 10.0 4.0 4.3 7.9 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFX93131.1 - 1.4 8.6 4.9 10 5.8 1.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3435 PF11917.3 KFX93134.1 - 6.2e-57 193.2 0.0 7.7e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Mito_carr PF00153.22 KFX93136.1 - 4.8e-57 189.6 9.0 7.1e-20 70.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.16 KFX93138.1 - 1.5e-58 198.1 0.7 1.9e-58 197.7 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KFX93138.1 - 1.4e-06 27.6 25.8 0.0059 15.6 14.5 2.4 1 1 0 2 2 2 2 ZIP Zinc transporter Spore_III_AE PF09546.5 KFX93138.1 - 0.14 11.0 2.0 0.16 10.9 0.6 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) Glyco_trans_1_4 PF13692.1 KFX93139.1 - 3.9e-23 82.0 0.0 6.9e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_12 PF13424.1 KFX93148.1 - 1.1e-61 204.7 47.4 1e-10 41.4 0.4 12.8 10 2 2 12 12 12 11 Tetratricopeptide repeat Ank_2 PF12796.2 KFX93148.1 - 4.2e-44 148.8 0.0 1.2e-14 54.4 0.0 6.7 4 2 1 6 6 5 5 Ankyrin repeats (3 copies) TPR_10 PF13374.1 KFX93148.1 - 4.1e-42 140.9 34.3 6.1e-06 25.9 0.0 17.5 20 0 0 20 20 19 10 Tetratricopeptide repeat Ank PF00023.25 KFX93148.1 - 6.6e-32 107.7 19.8 1.7e-05 24.3 0.1 11.6 10 1 1 11 11 11 6 Ankyrin repeat Ank_3 PF13606.1 KFX93148.1 - 2.6e-26 89.0 18.1 0.0012 18.8 0.0 12.6 13 0 0 13 13 12 5 Ankyrin repeat Pkinase PF00069.20 KFX93148.1 - 6e-22 78.0 0.0 1.4e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.1 KFX93148.1 - 1.2e-21 76.6 7.7 1.2e-07 32.0 0.0 8.8 5 3 3 9 9 9 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX93148.1 - 1.3e-19 69.7 2.8 8.2e-06 25.8 0.0 8.6 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KFX93148.1 - 7e-19 67.8 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_7 PF13176.1 KFX93148.1 - 6.8e-08 31.7 17.7 0.15 11.8 0.1 9.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93148.1 - 2.2e-07 31.3 21.9 0.009 16.6 0.5 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat Sel1 PF08238.7 KFX93148.1 - 0.00066 20.2 0.5 0.0043 17.6 0.0 2.7 2 0 0 2 2 2 1 Sel1 repeat TPR_2 PF07719.12 KFX93148.1 - 0.0042 16.9 34.2 1.9 8.6 0.1 10.1 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFX93148.1 - 0.0089 15.6 26.6 1.2 8.8 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93148.1 - 0.82 10.0 18.7 0.47 10.8 0.1 6.7 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX93148.1 - 2.2 8.2 13.7 17 5.4 0.5 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Glycogen_syn PF05693.8 KFX93150.1 - 0 1138.4 0.0 0 1138.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KFX93150.1 - 1.3e-06 27.9 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFX93150.1 - 8e-06 26.0 0.1 2.5e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 KFX93150.1 - 8.8e-06 25.3 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Sec5 PF15469.1 KFX93152.1 - 0.025 14.2 0.3 0.037 13.7 0.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 zf-C3HC4_2 PF13923.1 KFX93153.1 - 2.5e-07 30.5 9.7 4.2e-07 29.8 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX93153.1 - 3.8e-07 29.6 8.7 6.5e-07 28.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX93153.1 - 3.7e-06 26.4 6.0 6.3e-06 25.7 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX93153.1 - 5e-06 26.2 8.9 8.5e-06 25.5 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFX93153.1 - 1.3e-05 25.0 8.0 2.5e-05 24.0 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFX93153.1 - 6.2e-05 22.6 6.6 0.00012 21.7 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFX93153.1 - 0.11 12.2 6.1 0.23 11.2 4.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger CbiC PF02570.10 KFX93153.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase UCH PF00443.24 KFX93154.1 - 5.3e-49 166.7 0.0 1.2e-48 165.5 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX93154.1 - 7.6e-20 71.5 0.0 4.8e-19 68.9 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SET PF00856.23 KFX93155.1 - 1.7e-09 38.2 0.0 6.1e-06 26.6 0.0 2.9 3 0 0 3 3 3 2 SET domain Apc3 PF12895.2 KFX93155.1 - 0.00043 20.3 0.4 0.001 19.1 0.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFX93155.1 - 0.0016 18.7 0.3 0.0089 16.3 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX93155.1 - 0.0034 17.0 6.1 0.0088 15.6 0.2 3.0 2 1 2 4 4 4 1 TPR repeat DUF1955 PF09205.5 KFX93155.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) TPR_16 PF13432.1 KFX93155.1 - 0.14 12.8 5.5 1.4 9.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93155.1 - 3.7 7.6 5.9 30 4.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat GFA PF04828.9 KFX93156.1 - 7.8e-09 35.3 1.4 1.2e-05 25.1 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KFX93156.1 - 0.064 13.5 0.1 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar TFIID-18kDa PF02269.11 KFX93157.1 - 6.1e-31 106.0 0.9 2.5e-30 104.1 0.0 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit LCM PF04072.9 KFX93158.1 - 6.1e-26 91.1 0.0 8.1e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Med30 PF11315.3 KFX93164.1 - 0.032 14.3 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 30 Ofd1_CTDD PF10637.4 KFX93168.1 - 5e-37 127.4 3.6 6.5e-37 127.1 2.5 1.2 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term Limkain-b1 PF11608.3 KFX93168.1 - 0.059 13.1 0.4 0.13 12.0 0.3 1.6 1 0 0 1 1 1 0 Limkain b1 AA_permease PF00324.16 KFX93169.1 - 2.4e-119 398.8 40.7 2.9e-119 398.5 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX93169.1 - 7e-38 130.2 42.5 1.1e-37 129.6 29.4 1.2 1 0 0 1 1 1 1 Amino acid permease WTF PF03303.8 KFX93169.1 - 6.7 6.0 9.1 25 4.1 6.2 2.1 1 1 0 1 1 1 0 WTF protein Peptidase_M16_C PF05193.16 KFX93170.1 - 1.3e-13 51.0 0.0 6.2e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Ribosomal_S7 PF00177.16 KFX93173.1 - 3e-39 133.9 1.8 3.7e-39 133.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.10 KFX93174.1 - 2.6e-40 136.6 3.5 2.9e-40 136.5 2.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KFX93174.1 - 0.0084 15.7 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.7 KFX93174.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.1 KFX93174.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 KFX93174.1 - 0.034 14.2 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Cyt-b5 PF00173.23 KFX93175.1 - 5.8e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HAND PF09110.6 KFX93175.1 - 0.088 13.2 0.6 0.22 11.9 0.4 1.7 1 0 0 1 1 1 0 HAND DEAD PF00270.24 KFX93176.1 - 8e-33 113.3 0.9 2.8e-15 56.2 0.0 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX93176.1 - 7.6e-21 73.7 0.1 2.1e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX93176.1 - 3.5e-06 26.9 2.4 0.00029 20.7 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PIGA PF08288.7 KFX93177.1 - 1.8e-46 156.4 5.3 1.8e-46 156.4 1.3 2.5 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KFX93177.1 - 1.5e-28 99.4 0.0 2.3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX93177.1 - 8e-18 64.8 0.1 1.4e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFX93177.1 - 3.4e-16 59.4 0.6 6.2e-16 58.6 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KFX93177.1 - 4.4e-14 52.9 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KFX93177.1 - 1.9e-06 27.7 0.3 3.6e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KFX93177.1 - 0.00087 19.5 0.0 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_hydro_10 PF00331.15 KFX93178.1 - 1.4e-102 342.9 0.0 1.6e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 KFX93178.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF59 PF01883.14 KFX93178.1 - 0.11 12.4 0.2 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF59 NPR3 PF03666.8 KFX93179.1 - 1.5e-128 429.1 0.1 2.3e-128 428.5 0.1 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CHCH PF06747.8 KFX93180.1 - 4.4e-05 23.2 0.5 8.1e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KFX93180.1 - 0.045 13.7 2.5 0.48 10.4 2.0 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KFX93180.1 - 0.17 11.6 1.6 0.65 9.8 1.1 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KFX93180.1 - 0.27 11.2 2.2 2 8.5 0.2 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GFA PF04828.9 KFX93181.1 - 2.6e-11 43.3 0.5 4e-11 42.7 0.3 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Macoilin PF09726.4 KFX93182.1 - 3.2 5.9 15.7 3.4 5.8 10.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Pga1 PF10333.4 KFX93195.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.7 1 1 1 2 2 2 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.20 KFX93196.1 - 4.8e-70 235.7 0.0 6.6e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX93196.1 - 1.8e-48 163.7 0.1 3.3e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFX93196.1 - 0.0023 17.4 0.0 0.0051 16.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 KFX93197.1 - 7.5e-34 115.5 0.0 2.3e-14 52.9 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KFX93197.1 - 7.4e-10 38.8 0.0 0.00029 20.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair IncA PF04156.9 KFX93197.1 - 3.8e-09 36.4 24.5 1.3e-07 31.4 3.7 2.2 1 1 1 2 2 2 2 IncA protein EF-hand_1 PF00036.27 KFX93197.1 - 1.1e-06 27.4 0.0 0.12 11.7 0.0 4.9 5 0 0 5 5 5 1 EF hand UBA PF00627.26 KFX93197.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Macoilin PF09726.4 KFX93197.1 - 0.00031 19.1 17.8 0.00071 17.9 12.3 1.5 1 0 0 1 1 1 1 Transmembrane protein EF-hand_6 PF13405.1 KFX93197.1 - 0.00039 20.0 0.0 4.9 7.3 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain CCDC144C PF14915.1 KFX93197.1 - 0.0016 17.4 25.5 0.0028 16.6 17.7 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region MAD PF05557.8 KFX93197.1 - 0.018 13.1 22.5 0.028 12.5 15.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein EF-hand_8 PF13833.1 KFX93197.1 - 0.025 14.1 0.0 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair Reo_sigmaC PF04582.7 KFX93197.1 - 0.047 12.8 13.5 0.015 14.4 2.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein EzrA PF06160.7 KFX93197.1 - 0.057 11.5 18.4 0.098 10.8 12.8 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 KFX93197.1 - 0.12 12.2 32.5 0.14 11.9 13.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GOLGA2L5 PF15070.1 KFX93197.1 - 0.14 10.6 22.1 0.22 9.9 15.3 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 ATG16 PF08614.6 KFX93197.1 - 0.33 10.7 32.5 0.13 12.0 7.0 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.7 KFX93197.1 - 0.43 10.5 17.3 1.5 8.7 0.7 3.5 1 1 2 3 3 3 0 MbeD/MobD like TPR_MLP1_2 PF07926.7 KFX93197.1 - 0.52 10.0 33.5 1.4 8.6 13.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 KFX93197.1 - 0.69 7.1 32.9 0.96 6.6 22.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tnp_P_element PF12017.3 KFX93197.1 - 0.9 8.7 6.8 0.16 11.1 2.0 1.7 1 1 0 1 1 1 0 Transposase protein Spc7 PF08317.6 KFX93197.1 - 0.93 8.0 29.6 0.094 11.3 5.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 KFX93197.1 - 1 9.1 11.0 0.17 11.6 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GP41 PF00517.12 KFX93197.1 - 1.3 8.5 12.0 2.2 7.8 1.0 2.2 2 0 0 2 2 2 0 Retroviral envelope protein DUF2968 PF11180.3 KFX93197.1 - 1.8 7.9 27.3 2.3 7.5 9.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Fib_alpha PF08702.5 KFX93197.1 - 3.4 7.7 21.8 0.1 12.7 6.2 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 KFX93197.1 - 4.7 7.2 36.9 5.4 7.0 13.3 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2730 PF10805.3 KFX93197.1 - 6.5 6.5 11.0 2.7 7.7 2.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) eIF-3_zeta PF05091.7 KFX93212.1 - 2.6e-79 267.2 0.1 3e-79 267.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 KFX93212.1 - 0.0085 15.5 0.0 0.026 13.9 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF569) Arif-1 PF06770.6 KFX93213.1 - 0.013 14.8 0.5 0.013 14.8 0.3 1.7 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) HgmA PF04209.8 KFX93221.1 - 6.3e-125 416.9 0.0 7e-125 416.7 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.17 KFX93222.1 - 8.5e-66 222.3 0.0 9.8e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 KFX93223.1 - 1.9e-09 37.3 0.3 2.5e-08 33.6 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX93223.1 - 1.6e-07 31.4 0.1 2.7e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX93223.1 - 4e-07 29.5 0.0 6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFX93223.1 - 1.6e-06 27.0 0.1 2.8e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFX93223.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 KFX93223.1 - 0.005 15.7 0.9 0.015 14.2 0.1 1.8 1 1 1 2 2 2 1 Male sterility protein ApbA PF02558.11 KFX93223.1 - 0.0094 15.4 0.1 0.019 14.4 0.1 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KFX93223.1 - 0.014 15.7 0.1 0.04 14.3 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFX93223.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 KFX93223.1 - 0.046 14.1 0.2 0.092 13.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFX93223.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4046 PF13255.1 KFX93223.1 - 0.092 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) ADH_zinc_N PF00107.21 KFX93223.1 - 0.11 12.0 0.2 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PMT PF02366.13 KFX93235.1 - 3.4e-80 268.9 14.3 3.4e-80 268.9 9.9 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFX93235.1 - 7.9e-39 133.1 0.3 1.1e-38 132.7 0.2 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 KFX93236.1 - 1.1e-102 343.9 19.0 1.3e-102 343.7 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93236.1 - 1e-31 109.9 44.7 5.9e-29 100.8 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX93236.1 - 3.9e-06 25.5 20.6 0.00075 18.0 2.9 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KFX93236.1 - 0.002 16.8 1.1 0.0034 16.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KFX93236.1 - 0.0086 15.8 0.1 0.0086 15.8 0.1 2.3 3 0 0 3 3 3 1 MFS_1 like family MFS_3 PF05977.8 KFX93236.1 - 0.17 9.9 4.7 0.46 8.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 KFX93237.1 - 7.8e-101 336.9 5.9 9.2e-101 336.6 4.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF998 PF06197.8 KFX93237.1 - 0.0012 18.2 15.1 0.031 13.5 4.8 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF998) YvrJ PF12841.2 KFX93237.1 - 0.038 13.2 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 YvrJ protein family DUF202 PF02656.10 KFX93237.1 - 0.96 9.7 0.0 0.96 9.7 0.0 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF202) Ssl1 PF04056.9 KFX93238.1 - 4.9e-51 173.0 0.0 6.3e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KFX93238.1 - 8.2e-09 35.7 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFX93238.1 - 0.0046 16.6 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain MFS_1 PF07690.11 KFX93241.1 - 5.3e-34 117.4 57.0 3.2e-33 114.9 39.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX93241.1 - 3.4e-07 28.8 23.5 4.5e-07 28.4 16.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4006 PF13179.1 KFX93241.1 - 0.34 10.4 1.6 1.5 8.3 1.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Sterol-sensing PF12349.3 KFX93244.1 - 2.7e-42 143.8 6.2 5.5e-42 142.8 4.3 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFX93244.1 - 2.5e-14 52.1 1.5 3.6e-14 51.6 1.0 1.1 1 0 0 1 1 1 1 Patched family Nup160 PF11715.3 KFX93244.1 - 0.014 13.5 0.3 0.03 12.4 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 WD40 PF00400.27 KFX93244.1 - 0.019 14.8 0.1 0.06 13.2 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Sugar_tr PF00083.19 KFX93245.1 - 3.9e-84 282.8 22.0 4.4e-84 282.6 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93245.1 - 6.1e-29 100.8 31.1 2.6e-18 65.8 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SseB PF07179.7 KFX93246.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 SseB protein N-terminal domain Fungal_trans PF04082.13 KFX93248.1 - 4.7e-07 28.9 1.2 8.9e-07 28.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93248.1 - 3.4e-06 26.8 8.8 3.4e-06 26.8 6.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAM-associated PF14303.1 KFX93248.1 - 0.11 12.7 4.1 0.22 11.8 2.8 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MFS_1 PF07690.11 KFX93250.1 - 2.3e-27 95.6 48.1 7.2e-26 90.7 30.3 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX93250.1 - 5.7e-20 71.0 14.6 2.2e-19 69.0 10.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX93250.1 - 1.1e-13 50.5 0.6 1.1e-13 50.5 0.4 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 KFX93253.1 - 7.2e-22 78.3 1.3 8.3e-22 78.1 0.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX93253.1 - 2.3e-08 33.8 0.1 2.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LANC_like PF05147.8 KFX93254.1 - 4.9e-22 77.9 0.0 1.4e-21 76.4 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Glyco_transf_54 PF04666.8 KFX93255.1 - 4.7e-11 41.9 0.1 4.3e-10 38.8 0.1 2.1 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CAF-1_p150 PF11600.3 KFX93255.1 - 0.0015 17.9 10.2 0.0032 16.8 7.1 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glucos_trans_II PF14264.1 KFX93255.1 - 0.0094 14.9 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Glucosyl transferase GtrII DUF1705 PF08019.7 KFX93255.1 - 0.34 10.4 1.9 0.6 9.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) End_beta_barrel PF12195.3 KFX93256.1 - 0.044 13.5 0.1 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase Acetyltransf_1 PF00583.19 KFX93257.1 - 3.1e-08 33.5 0.0 5.1e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX93257.1 - 9.6e-07 28.8 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX93257.1 - 9.9e-07 28.8 0.0 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX93257.1 - 4.5e-05 23.1 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFX93257.1 - 0.00045 20.0 0.0 0.13 12.1 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX93257.1 - 0.0032 17.3 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Pyr_redox_2 PF07992.9 KFX93258.1 - 5.7e-28 98.1 0.0 9.7e-27 94.1 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX93258.1 - 1.2e-13 51.2 0.0 1.5e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX93258.1 - 8.2e-05 22.7 0.5 0.11 12.4 0.2 4.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF260 PF03195.9 KFX93258.1 - 0.16 12.2 0.1 8.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF260 HI0933_like PF03486.9 KFX93258.1 - 1.2 7.5 4.8 0.58 8.5 0.1 2.4 2 1 1 3 3 3 0 HI0933-like protein ABC_tran PF00005.22 KFX93259.1 - 4.8e-34 117.6 0.0 1.3e-33 116.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFX93259.1 - 2.3e-26 92.8 7.2 3.6e-26 92.1 5.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFX93259.1 - 2.3e-07 30.2 4.3 3.4e-06 26.4 3.0 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX93259.1 - 3.7e-05 23.8 0.2 0.029 14.3 0.2 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX93259.1 - 0.00059 19.8 0.2 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KFX93259.1 - 0.0013 18.6 0.2 0.013 15.3 0.2 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KFX93259.1 - 0.0032 16.9 0.1 0.0081 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX93259.1 - 0.0047 17.0 0.2 0.031 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX93259.1 - 0.0048 16.1 0.0 0.0099 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Pro_isomerase PF00160.16 KFX93265.1 - 4.4e-48 163.4 0.0 5.5e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFX93276.1 - 1.1e-13 50.5 0.2 2.8e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX93276.1 - 4e-11 42.7 0.2 1.2e-10 41.2 0.0 1.8 3 0 0 3 3 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX93276.1 - 0.00074 19.3 0.0 0.0019 17.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIMELESS_C PF05029.8 KFX93276.1 - 0.0098 14.8 2.0 0.011 14.7 1.4 1.1 1 0 0 1 1 1 1 Timeless protein C terminal region CENP-B_dimeris PF09026.5 KFX93276.1 - 0.013 15.7 3.5 0.02 15.0 2.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PRP21_like_P PF12230.3 KFX93276.1 - 0.014 14.8 1.8 0.019 14.4 1.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein PAN_3 PF08277.7 KFX93276.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 PAN-like domain YL1 PF05764.8 KFX93276.1 - 0.037 13.6 4.6 0.045 13.3 3.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein EB_dh PF09459.5 KFX93276.1 - 0.077 12.4 0.2 0.092 12.1 0.1 1.2 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase DUF1043 PF06295.7 KFX93276.1 - 0.12 12.0 4.6 0.24 11.0 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Nup35_RRM_2 PF14605.1 KFX93276.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PBP1_TM PF14812.1 KFX93276.1 - 0.23 11.8 3.8 0.4 11.0 2.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TSGP1 PF07771.6 KFX93276.1 - 1.4 8.8 4.9 0.52 10.2 0.8 2.0 2 0 0 2 2 2 0 Tick salivary peptide group 1 Nucleoplasmin PF03066.10 KFX93276.1 - 2.1 7.8 9.4 3.4 7.1 6.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin COQ7 PF03232.8 KFX93283.1 - 5.7e-50 169.1 0.1 6.3e-50 168.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PLDc PF00614.17 KFX93284.1 - 1.7e-17 62.5 1.1 2.6e-08 33.3 0.2 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFX93284.1 - 3.7e-12 46.0 0.1 1.5e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KFX93284.1 - 5.7e-07 29.3 0.1 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 PX domain DASH_Spc34 PF08657.5 KFX93291.1 - 1.9e-57 194.8 9.7 1.8e-56 191.6 6.7 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 SlyX PF04102.7 KFX93291.1 - 0.022 15.0 7.6 0.12 12.8 0.9 2.6 1 1 1 2 2 2 0 SlyX CENP-F_leu_zip PF10473.4 KFX93291.1 - 0.18 11.6 9.9 0.99 9.2 2.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Spc19 PF08287.6 KFX93291.1 - 0.64 9.6 5.6 1 8.9 3.8 1.4 1 1 0 1 1 1 0 Spc19 TFIID_20kDa PF03847.8 KFX93292.1 - 3.5e-22 78.4 0.0 5.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KFX93292.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX93292.1 - 0.0085 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Vasculin PF15337.1 KFX93292.1 - 0.059 13.8 0.2 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 ORC5_C PF14630.1 KFX93293.1 - 6.2e-41 140.6 0.0 1.7e-40 139.2 0.0 1.8 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KFX93293.1 - 8e-05 22.6 0.1 0.0004 20.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFX93293.1 - 0.066 12.8 0.0 0.32 10.6 0.0 2.2 3 0 0 3 3 3 0 NACHT domain TPT PF03151.11 KFX93294.1 - 1.1e-39 135.5 2.2 1.1e-39 135.5 1.6 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFX93294.1 - 1.6e-09 37.1 11.0 8.4e-09 34.7 7.6 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFX93294.1 - 0.0017 18.3 32.0 0.0091 16.0 5.3 3.5 3 2 0 3 3 3 2 EamA-like transporter family PSII PF00421.14 KFX93294.1 - 0.032 12.8 0.4 0.05 12.1 0.3 1.2 1 0 0 1 1 1 0 Photosystem II protein DUF382 PF04037.8 KFX93295.1 - 5.2e-61 204.1 0.5 5.2e-61 204.1 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KFX93295.1 - 1.7e-21 75.3 6.8 5.2e-21 73.7 4.7 1.9 1 0 0 1 1 1 1 PSP CN_hydrolase PF00795.17 KFX93296.1 - 6.5e-26 90.8 0.0 1.3e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KFX93296.1 - 8.2e-23 80.5 0.0 3.7e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 NAD synthase DUF544 PF04424.8 KFX93297.1 - 7e-12 45.2 0.0 2.5e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF544) DUF1388 PF07142.7 KFX93298.1 - 0.051 13.2 14.0 0.14 11.8 0.0 4.7 3 1 3 6 6 6 0 Repeat of unknown function (DUF1388) F-box-like PF12937.2 KFX93299.1 - 0.0024 17.5 1.1 0.0048 16.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like Ank PF00023.25 KFX93300.1 - 1.7e-68 223.2 29.7 1.3e-07 31.0 0.2 12.9 13 0 0 13 13 13 10 Ankyrin repeat Ank_2 PF12796.2 KFX93300.1 - 2.5e-68 226.4 19.0 8.4e-20 70.9 1.5 6.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX93300.1 - 5e-53 176.5 21.2 8.6e-11 42.0 0.2 8.8 5 1 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93300.1 - 3e-42 138.4 23.6 6.2e-05 22.8 0.3 11.6 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 KFX93300.1 - 2.8e-41 138.6 24.0 3.7e-08 33.3 1.1 10.0 5 3 6 11 11 11 7 Ankyrin repeats (many copies) DUF1843 PF08898.5 KFX93300.1 - 0.77 9.8 4.2 10 6.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Spc7 PF08317.6 KFX93302.1 - 0.4 9.2 34.4 0.023 13.3 12.2 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 KFX93302.1 - 3.4 5.9 35.8 4.6 5.5 23.6 1.8 1 1 1 2 2 2 0 AAA domain Na_H_Exchanger PF00999.16 KFX93303.1 - 9.3e-36 123.1 8.3 9.3e-36 123.1 5.8 4.0 3 2 1 4 4 4 2 Sodium/hydrogen exchanger family MFS_1 PF07690.11 KFX93303.1 - 4.9e-23 81.4 38.6 4.9e-23 81.4 26.8 3.9 3 1 1 4 4 4 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 KFX93304.1 - 7.7e-08 32.0 0.1 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX93304.1 - 5e-05 23.0 0.2 0.00033 20.3 0.1 2.2 2 1 0 2 2 2 1 Peptidase dimerisation domain Sugar_tr PF00083.19 KFX93305.1 - 1.5e-78 264.4 24.8 1.8e-78 264.1 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93305.1 - 5.4e-27 94.4 41.1 3.6e-23 81.8 16.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KFX93306.1 - 4.4e-36 124.3 44.0 4.4e-36 124.3 30.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX93306.1 - 5.6e-10 38.0 23.5 5.6e-10 38.0 16.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX93306.1 - 3.7e-07 29.0 38.2 4.6e-06 25.4 9.0 3.8 2 2 1 3 3 3 2 Sugar (and other) transporter GYF PF02213.11 KFX93307.1 - 4.2e-10 39.0 0.2 7.7e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 GYF domain Med2 PF11214.3 KFX93307.1 - 2.9 7.9 5.4 15 5.6 3.8 2.1 1 1 1 2 2 2 0 Mediator complex subunit 2 UFD1 PF03152.9 KFX93308.1 - 5.7e-72 240.5 0.0 7.4e-72 240.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 BolA PF01722.13 KFX93311.1 - 8.8e-17 60.8 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein tRNA-synt_1d PF00750.14 KFX93312.1 - 1.2e-83 280.9 9.3 3.6e-83 279.3 6.5 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KFX93312.1 - 1.4e-30 105.7 0.1 4e-30 104.2 0.1 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KFX93312.1 - 6.4e-07 29.8 0.0 1.7e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Hemerythrin PF01814.18 KFX93313.1 - 7.8e-07 29.3 0.0 9.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_61 PF03443.9 KFX93314.1 - 5.8e-51 173.3 0.0 7.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F5_F8_type_C PF00754.20 KFX93315.1 - 1.8e-10 40.7 0.0 5.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_42 PF02449.10 KFX93315.1 - 0.012 14.7 0.0 0.47 9.5 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase Sugar_tr PF00083.19 KFX93316.1 - 6.4e-79 265.6 25.1 7.4e-79 265.4 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93316.1 - 7.6e-39 133.4 53.3 2e-33 115.6 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX93316.1 - 0.037 12.2 10.7 0.0054 14.9 2.4 2.5 2 1 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) DUF202 PF02656.10 KFX93316.1 - 3.1 8.0 8.8 2.5 8.3 0.4 3.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Alpha-amylase PF00128.19 KFX93317.1 - 1.1e-96 323.9 0.2 1.1e-96 323.9 0.2 1.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFX93317.1 - 0.0011 17.9 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KFX93317.1 - 0.0077 16.3 0.3 0.069 13.3 0.2 2.6 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain DUF4202 PF13875.1 KFX93318.1 - 1e-77 260.0 0.6 1.1e-77 259.8 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF3505 PF12013.3 KFX93318.1 - 0.094 12.9 0.2 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Glyco_hydro_31 PF01055.21 KFX93319.1 - 1.2e-132 442.8 1.3 1.5e-132 442.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX93319.1 - 0.00033 20.4 1.1 0.0026 17.5 0.1 2.8 3 1 0 3 3 3 1 Galactose mutarotase-like Peptidase_M20 PF01546.23 KFX93320.1 - 5e-21 75.0 0.0 8e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX93320.1 - 1.6e-14 53.5 0.0 4.4e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.18 KFX93321.1 - 9e-17 61.6 0.2 1.3e-16 61.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX93321.1 - 0.00038 20.1 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFX93321.1 - 0.0097 14.9 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFX93321.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93321.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Mito_carr PF00153.22 KFX93328.1 - 3.1e-57 190.2 0.9 3e-20 71.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB PF00651.26 KFX93329.1 - 6.7e-07 29.2 0.0 3.1e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain PAF-AH_p_II PF03403.8 KFX93348.1 - 4.1e-09 35.2 0.1 3.5e-08 32.1 0.0 2.0 1 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFX93348.1 - 1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFX93348.1 - 0.00036 19.5 0.0 0.00057 18.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KFX93348.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX93348.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Ank_2 PF12796.2 KFX93349.1 - 4.5e-86 283.3 5.9 2e-18 66.5 0.0 5.4 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93349.1 - 4.6e-64 209.2 18.8 4.6e-05 23.0 0.0 13.2 11 2 2 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KFX93349.1 - 3.5e-56 186.6 3.3 7.6e-10 39.0 0.0 10.4 2 2 11 13 13 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93349.1 - 3e-54 175.5 2.4 0.00014 21.7 0.0 13.3 11 2 2 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 KFX93349.1 - 4.4e-43 144.3 12.1 6.7e-07 29.3 0.1 11.8 1 1 12 13 13 13 11 Ankyrin repeats (many copies) DUF4646 PF15496.1 KFX93349.1 - 5.7e-06 26.3 0.2 3.6e-05 23.7 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF1843 PF08898.5 KFX93349.1 - 0.013 15.4 0.1 31 4.7 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) DUF249 PF03158.8 KFX93349.1 - 0.048 13.1 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Multigene family 530 protein Shigella_OspC PF06128.6 KFX93349.1 - 0.082 12.4 4.5 33 3.8 0.0 5.5 7 1 1 8 8 8 0 Shigella flexneri OspC protein DUF2236 PF09995.4 KFX93351.1 - 6e-31 107.5 0.0 8e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2520 PF10728.4 KFX93351.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Glyco_hydro_30 PF02055.11 KFX93352.1 - 6.8e-35 120.2 0.8 1.5e-18 66.2 0.1 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 DUF3425 PF11905.3 KFX93352.1 - 9.6e-19 67.6 1.5 3.8e-18 65.6 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX93352.1 - 6.1e-05 22.8 7.6 0.0014 18.5 5.4 2.5 1 1 1 2 2 2 2 bZIP transcription factor Sugar_tr PF00083.19 KFX93353.1 - 6.9e-46 156.7 1.7 8.9e-46 156.3 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93353.1 - 3.2e-29 101.7 32.3 3.2e-29 101.7 22.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KFX93353.1 - 0.00017 20.2 15.8 0.0014 17.2 5.5 2.2 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KFX93353.1 - 0.0016 18.1 0.1 2.7 7.8 0.0 2.9 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.15 KFX93353.1 - 0.043 11.8 1.0 0.05 11.6 0.0 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.14 KFX93353.1 - 0.59 8.6 8.1 1.6 7.1 4.0 2.3 1 1 1 2 2 2 0 LacY proton/sugar symporter Phosphoesterase PF04185.9 KFX93354.1 - 2.3e-66 224.5 2.8 3.2e-66 224.0 1.9 1.2 1 0 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 KFX93355.1 - 2.3e-56 190.6 3.1 2.8e-56 190.3 2.2 1.0 1 0 0 1 1 1 1 VIT family Pyr_redox_3 PF13738.1 KFX93356.1 - 4.9e-25 88.7 0.0 2.1e-24 86.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX93356.1 - 7.9e-14 51.3 0.0 3.1e-10 39.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFX93356.1 - 1.4e-12 46.6 0.0 4.3e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX93356.1 - 5.1e-07 29.7 0.0 0.00018 21.4 0.0 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX93356.1 - 0.00028 19.9 0.0 0.0042 16.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX93356.1 - 0.00032 20.5 0.1 0.078 12.7 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX93356.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GDI PF00996.13 KFX93356.1 - 0.011 14.0 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Thi4 PF01946.12 KFX93356.1 - 0.039 13.0 0.0 0.09 11.8 0.0 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KFX93356.1 - 0.093 11.1 0.1 6.6 5.0 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein MFS_1 PF07690.11 KFX93357.1 - 3.7e-22 78.5 31.2 3.7e-22 78.5 21.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta_elim_lyase PF01212.16 KFX93358.1 - 7.3e-64 215.6 0.0 9.2e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFX93358.1 - 0.009 15.0 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 KFX93359.1 - 6.3e-07 28.8 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KFX93359.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX93359.1 - 0.0082 15.8 0.2 0.59 9.8 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFX93359.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MNHE PF01899.11 KFX93360.1 - 0.00072 19.2 0.4 0.0008 19.0 0.3 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit Peptidase_M20 PF01546.23 KFX93361.1 - 9.1e-27 93.7 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX93361.1 - 1.9e-10 40.4 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Abhydrolase_6 PF12697.2 KFX93363.1 - 7.9e-32 110.9 0.0 9e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX93363.1 - 1.4e-18 67.2 0.0 5.8e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX93363.1 - 3.2e-16 59.3 0.0 9.3e-16 57.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFX93363.1 - 1.4e-06 27.0 0.0 3.2e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family DUF1749 PF08538.5 KFX93363.1 - 4.5e-06 25.7 0.0 0.00025 20.0 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.8 KFX93363.1 - 0.00022 20.8 0.0 0.0012 18.4 0.0 2.0 1 1 1 2 2 2 1 Serine hydrolase BAAT_C PF08840.6 KFX93363.1 - 0.00042 20.0 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KFX93363.1 - 0.0021 17.5 0.0 8.9 5.6 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF1057 PF06342.7 KFX93363.1 - 0.004 16.0 0.0 0.005 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF2305 PF10230.4 KFX93363.1 - 0.0058 16.0 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Esterase_phd PF10503.4 KFX93363.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX93363.1 - 0.015 14.5 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFX93363.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KFX93363.1 - 0.036 13.4 0.0 0.046 13.1 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_8 PF06259.7 KFX93363.1 - 0.04 13.4 0.5 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase PGAP1 PF07819.8 KFX93363.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.8 KFX93363.1 - 0.15 10.3 0.1 2.3 6.4 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Alkyl_sulf_dimr PF14863.1 KFX93364.1 - 5.9e-58 195.1 0.1 1.1e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 KFX93364.1 - 3e-27 95.0 0.0 5.8e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 KFX93364.1 - 1.5e-25 90.0 0.0 2.6e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX93364.1 - 0.0048 16.4 0.0 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TPR_11 PF13414.1 KFX93364.1 - 0.0084 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 KFX93364.1 - 0.11 13.1 0.1 3.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1583 PF07622.6 KFX93364.1 - 0.14 10.6 0.0 0.23 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) p450 PF00067.17 KFX93365.1 - 1.6e-20 73.1 0.0 4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KFX93365.1 - 1.5e-09 38.0 0.0 3.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase FAD_binding_3 PF01494.14 KFX93365.1 - 7.5e-08 31.8 0.0 0.068 12.2 0.1 3.3 3 0 0 3 3 3 2 FAD binding domain KR PF08659.5 KFX93365.1 - 1.3e-06 28.2 0.0 2.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_8 PF13450.1 KFX93365.1 - 0.0006 19.7 0.1 0.0016 18.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KFX93365.1 - 0.0061 16.6 0.3 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KFX93365.1 - 0.026 13.5 0.1 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KFX93365.1 - 0.04 14.2 0.2 8.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KFX93365.1 - 0.053 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.1 KFX93365.1 - 0.06 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DAO PF01266.19 KFX93365.1 - 0.1 11.5 0.2 0.22 10.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aminotran_1_2 PF00155.16 KFX93366.1 - 2.7e-46 158.1 0.0 3.2e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFX93366.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.16 KFX93366.1 - 0.08 11.7 0.0 0.34 9.6 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-III BNR_2 PF13088.1 KFX93368.1 - 2.1e-06 27.2 0.0 0.00037 19.8 0.0 2.4 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KFX93368.1 - 0.0012 18.3 9.5 0.23 11.4 0.0 4.2 4 0 0 4 4 4 2 BNR/Asp-box repeat Sua5_yciO_yrdC PF01300.13 KFX93369.1 - 1.4e-54 184.0 0.0 1.9e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KFX93369.1 - 9.5e-26 90.3 0.0 2.6e-25 88.9 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.15 KFX93370.1 - 1.2e-14 54.2 0.2 1.3e-13 50.9 0.3 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain MCM PF00493.18 KFX93371.1 - 2.3e-140 467.0 0.0 3.3e-140 466.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFX93371.1 - 8.7e-25 87.5 0.1 3.5e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFX93371.1 - 2.6e-06 26.7 0.0 0.00015 20.9 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFX93371.1 - 2.9e-05 23.8 0.1 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFX93371.1 - 0.00042 19.9 0.0 0.0015 18.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.5 KFX93371.1 - 0.061 13.2 1.0 0.15 12.0 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Sigma54_activat PF00158.21 KFX93371.1 - 0.091 12.2 0.2 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Abhydrolase_6 PF12697.2 KFX93376.1 - 8.7e-21 74.8 0.3 1.1e-20 74.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX93376.1 - 3.4e-08 33.3 0.0 4.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3425 PF11905.3 KFX93377.1 - 5.1e-15 55.5 1.1 5.8e-14 52.1 0.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Ank_2 PF12796.2 KFX93378.1 - 7.8e-12 45.3 0.2 5.6e-09 36.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93378.1 - 1.4e-11 43.6 1.2 0.0031 17.2 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFX93378.1 - 2.4e-09 37.4 0.2 7.2e-08 32.7 0.0 3.3 3 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93378.1 - 1.6e-07 30.8 0.5 0.37 11.1 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KFX93378.1 - 1.7e-05 24.9 0.0 0.016 15.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) WSC PF01822.14 KFX93379.1 - 9.7e-31 105.5 18.9 1.1e-17 63.7 5.0 3.4 3 0 0 3 3 3 2 WSC domain CENP-B_N PF04218.8 KFX93385.1 - 1.4e-08 34.0 0.5 3e-08 32.9 0.3 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain zf-H2C2_5 PF13909.1 KFX93385.1 - 0.033 14.4 1.3 0.11 12.7 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF2481 PF10654.4 KFX93385.1 - 0.057 13.1 0.3 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) HTH_23 PF13384.1 KFX93385.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Exo_endo_phos PF03372.18 KFX93389.1 - 7.8e-15 55.4 0.1 1.5e-14 54.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1034 PF06280.7 KFX93389.1 - 0.0039 17.5 0.0 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Lantibiotic_a PF14867.1 KFX93389.1 - 0.021 14.0 0.6 0.042 13.0 0.2 1.7 2 0 0 2 2 2 0 Lantibiotic alpha DCP1 PF06058.8 KFX93390.1 - 1.3e-18 67.2 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Glyco_hydro_1 PF00232.13 KFX93391.1 - 7.1e-154 512.3 0.0 7.9e-154 512.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Histidinol_dh PF00815.15 KFX93398.1 - 1.9e-160 534.0 4.2 3.3e-160 533.2 2.9 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KFX93398.1 - 2.4e-24 84.7 0.1 5.2e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KFX93398.1 - 1.5e-10 41.2 0.3 6.3e-10 39.1 0.2 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_11 PF13414.1 KFX93398.1 - 9.6e-09 34.7 0.0 2.9e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KFX93398.1 - 4.8e-05 22.9 0.0 0.00017 21.2 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX93398.1 - 0.00023 20.6 0.0 0.00088 18.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93398.1 - 0.017 15.7 0.0 0.062 13.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MazG PF03819.12 KFX93398.1 - 0.17 11.8 2.6 0.2 11.6 0.7 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain TFIID-31kDa PF02291.10 KFX93399.1 - 8.7e-30 103.1 0.0 3.9e-29 101.0 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PUA PF01472.15 KFX93400.1 - 1.5e-13 50.2 0.3 5.2e-13 48.5 0.2 1.8 1 1 0 1 1 1 1 PUA domain Inhibitor_I78 PF11720.3 KFX93401.1 - 2.2e-09 36.9 0.0 2.7e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KFX93401.1 - 0.0088 16.1 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 Potato inhibitor I family FTP PF07504.8 KFX93401.1 - 0.085 12.3 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DUF1049 PF06305.6 KFX93402.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Sulfate_tra_GLY PF13792.1 KFX93402.1 - 0.43 10.2 2.7 6 6.6 0.1 2.5 3 0 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif DUF1992 PF09350.5 KFX93403.1 - 4.7e-21 74.3 0.0 1.5e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Pyocin_S PF06958.7 KFX93403.1 - 0.13 12.6 4.9 0.054 13.8 1.2 1.8 2 0 0 2 2 2 0 S-type Pyocin ENTH PF01417.15 KFX93409.1 - 4.5e-47 159.0 0.3 5.9e-47 158.6 0.2 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KFX93409.1 - 0.00078 18.2 0.0 0.001 17.8 0.0 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KFX93409.1 - 0.073 12.7 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain UPF0020 PF01170.13 KFX93409.1 - 0.087 12.3 0.3 0.15 11.6 0.2 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Pro_isomerase PF00160.16 KFX93410.1 - 1.7e-39 135.5 0.6 2.2e-39 135.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 KFX93414.1 - 4.8e-22 78.4 0.0 6.1e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 KFX93415.1 - 4.4e-43 147.1 0.5 7.6e-43 146.4 0.4 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Frag1 PF10277.4 KFX93416.1 - 4.9e-39 134.0 6.4 5.6e-39 133.8 4.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.12 KFX93416.1 - 0.00091 17.9 7.0 0.0011 17.7 4.9 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Bac_Ubq_Cox PF01654.12 KFX93416.1 - 0.02 13.3 2.5 0.022 13.1 0.4 1.8 1 1 1 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase Cation_ATPase_C PF00689.16 KFX93416.1 - 0.03 13.8 6.6 0.043 13.3 4.5 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF1422 PF07226.6 KFX93416.1 - 0.12 12.0 1.1 0.27 10.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1422) TPR_11 PF13414.1 KFX93417.1 - 2e-47 158.7 27.9 7.2e-16 57.5 5.9 6.6 3 2 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 KFX93417.1 - 7.6e-39 128.5 20.6 8.6e-08 31.5 0.2 8.8 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.23 KFX93417.1 - 1.3e-34 116.3 20.2 2.3e-06 26.9 0.2 9.2 9 1 1 10 10 10 6 Tetratricopeptide repeat DnaJ PF00226.26 KFX93417.1 - 7.5e-28 96.0 5.5 3.7e-27 93.8 3.8 2.3 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.1 KFX93417.1 - 5.8e-24 84.1 14.9 1.4e-06 28.8 0.8 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93417.1 - 3.2e-20 72.2 21.9 2.9e-05 24.3 0.1 6.5 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFX93417.1 - 6.6e-20 69.8 16.5 1.9e-05 24.8 0.2 8.3 3 3 5 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFX93417.1 - 9.2e-19 66.0 17.5 0.0016 18.4 0.0 8.3 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 KFX93417.1 - 1.3e-17 63.3 7.9 0.00014 21.6 0.1 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFX93417.1 - 8.3e-17 60.9 21.3 5.5e-07 29.4 0.8 6.3 4 3 2 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFX93417.1 - 3.9e-15 54.4 20.8 0.0027 17.3 0.0 8.7 9 1 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 KFX93417.1 - 6.6e-15 55.0 9.7 4.1e-07 30.0 0.8 4.3 2 2 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFX93417.1 - 1.9e-14 52.2 18.4 0.012 15.3 0.0 8.2 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFX93417.1 - 1.6e-10 40.7 18.0 0.0052 17.1 0.1 8.8 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFX93417.1 - 2e-08 33.8 0.3 0.062 13.7 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 KFX93417.1 - 1.1e-07 32.2 6.8 0.26 11.5 0.1 4.8 3 2 0 3 3 3 3 Bacterial transcriptional activator domain TPR_15 PF13429.1 KFX93417.1 - 2e-06 27.0 13.5 0.017 14.1 0.6 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat Coatomer_E PF04733.9 KFX93417.1 - 0.00018 20.8 4.0 0.12 11.5 0.2 3.2 2 1 0 3 3 3 2 Coatomer epsilon subunit Fis1_TPR_C PF14853.1 KFX93417.1 - 0.00075 19.3 10.6 4.7 7.1 0.0 6.1 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 KFX93417.1 - 0.0021 18.1 15.3 0.055 13.5 0.1 5.4 2 2 3 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.4 KFX93417.1 - 0.0061 16.5 16.9 0.13 12.2 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.5 KFX93417.1 - 0.0063 15.3 0.4 0.015 14.0 0.1 1.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KFX93417.1 - 0.0091 15.8 16.7 1 9.3 0.2 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF928 PF06051.7 KFX93417.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) PPR PF01535.15 KFX93417.1 - 0.028 14.4 0.1 15 5.7 0.0 4.1 5 0 0 5 5 2 0 PPR repeat DUF3366 PF11846.3 KFX93417.1 - 0.17 11.7 6.6 2.4 8.0 2.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3366) Peptidase_C50 PF03568.12 KFX93418.1 - 9.9e-117 389.8 0.0 1.4e-116 389.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KFX93418.1 - 1e-07 31.7 17.3 2.7e-05 24.0 0.2 6.9 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93418.1 - 0.013 15.3 11.1 6.8 6.8 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1654 PF07867.6 KFX93419.1 - 0.27 10.6 3.9 0.44 9.9 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) SIR2 PF02146.12 KFX93420.1 - 2.8e-30 105.3 0.0 4.4e-30 104.7 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 KFX93421.1 - 5.6e-54 183.1 1.0 7.5e-54 182.7 0.7 1.1 1 0 0 1 1 1 1 Cation efflux family LIM PF00412.17 KFX93422.1 - 7.4e-05 22.7 2.7 7.4e-05 22.7 1.9 2.3 2 0 0 2 2 2 1 LIM domain Iso_dh PF00180.15 KFX93423.1 - 1.3e-123 412.3 0.0 1.5e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 KFX93425.1 - 9.5e-08 31.6 12.5 1.5e-07 30.9 8.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 KFX93425.1 - 0.11 12.1 5.4 0.24 11.1 3.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger EGF_2 PF07974.8 KFX93426.1 - 8.5e-05 22.6 5.4 0.00021 21.4 3.8 1.7 1 1 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFX93426.1 - 0.0036 17.2 4.4 0.0094 15.9 3.0 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF Laminin_EGF PF00053.19 KFX93426.1 - 0.48 10.3 3.9 0.94 9.4 2.7 1.4 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) DUF4451 PF14616.1 KFX93429.1 - 3.9e-35 120.3 0.4 7.6e-35 119.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Med10 PF09748.4 KFX93430.1 - 4.2e-38 130.0 0.0 4.9e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Xpo1 PF08389.7 KFX93431.1 - 3.5e-38 130.8 0.1 3e-37 127.8 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KFX93431.1 - 0.0045 16.9 0.2 24 5.3 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat EF-hand_6 PF13405.1 KFX93433.1 - 2.6e-11 42.4 1.1 3e-05 23.5 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFX93433.1 - 1.8e-10 39.3 1.4 0.00029 19.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFX93433.1 - 4.2e-07 30.0 0.9 0.024 14.7 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFX93433.1 - 4.5e-06 25.7 5.3 0.0007 18.8 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFX93433.1 - 4.9e-06 26.0 0.4 0.032 13.8 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 KFX93433.1 - 0.0011 18.8 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain ORC6 PF05460.8 KFX93433.1 - 1.2 8.1 10.5 1.7 7.6 7.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Afi1 PF07792.7 KFX93434.1 - 5.9e-66 220.9 0.0 1.3e-65 219.8 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KFX93434.1 - 8.4e-39 131.7 0.0 1.7e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFX93434.1 - 7.3e-09 34.5 0.0 0.0075 14.7 0.0 4.0 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 KFX93434.1 - 0.007 15.6 0.0 0.066 12.4 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Esterase PF00756.15 KFX93435.1 - 9.2e-52 175.9 0.0 1.1e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KFX93435.1 - 6.6e-07 29.1 0.0 8.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFX93435.1 - 9.6e-06 24.9 0.0 0.00065 19.0 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX93435.1 - 5.4e-05 22.5 0.0 8.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KFX93435.1 - 0.0016 17.3 0.0 0.0036 16.2 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KFX93435.1 - 0.0021 17.9 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KFX93435.1 - 0.0055 15.5 0.0 0.12 11.1 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase AXE1 PF05448.7 KFX93435.1 - 0.013 13.9 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KFX93435.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KFX93435.1 - 0.03 13.5 0.3 0.15 11.2 0.1 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFX93435.1 - 0.078 12.4 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KFX93435.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.8 KFX93435.1 - 0.13 10.4 0.0 0.23 9.6 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 KFX93435.1 - 0.15 11.6 0.2 1.1 8.7 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold RNA_pol_Rpb6 PF01192.17 KFX93436.1 - 1.5e-24 85.4 0.3 2.2e-24 84.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 KFX93437.1 - 7.7e-06 25.9 4.9 0.00091 19.4 0.3 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX93437.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 3.7 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX93437.1 - 6.4e-05 23.0 12.6 0.003 17.7 0.2 3.3 2 1 1 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KFX93437.1 - 0.0011 19.0 0.4 0.56 10.4 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KFX93437.1 - 0.018 15.3 2.3 0.038 14.3 1.6 1.5 1 1 0 1 1 1 0 TRAF-type zinc finger DUF2782 PF11191.3 KFX93437.1 - 0.043 13.7 0.6 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2782) zf-C2H2_jaz PF12171.3 KFX93437.1 - 0.095 12.8 4.7 0.35 11.0 1.7 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFX93437.1 - 6 7.0 7.5 2.6 8.2 2.3 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MMR_HSR1 PF01926.18 KFX93454.1 - 4.3e-15 55.6 0.0 6.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX93454.1 - 1.2e-05 24.6 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX93454.1 - 0.0022 17.1 0.3 0.0039 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFX93454.1 - 0.0061 16.3 0.2 0.19 11.5 0.1 2.2 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 KFX93454.1 - 0.013 14.2 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 KFX93454.1 - 0.06 13.6 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFX93454.1 - 0.12 13.1 0.1 0.21 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.20 KFX93455.1 - 5.3e-70 235.6 0.0 9.2e-70 234.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX93455.1 - 3.3e-49 166.1 0.1 5.3e-49 165.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFX93455.1 - 1.9e-05 24.7 0.2 4.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFX93455.1 - 0.0043 16.5 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.22 KFX93456.1 - 1.1e-46 158.5 0.2 7.9e-22 78.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KFX93456.1 - 1.7e-19 69.4 5.7 1.7e-19 69.4 3.9 3.4 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 KFX93456.1 - 7.9e-16 58.8 5.1 0.0005 20.1 0.0 4.9 5 1 1 6 6 5 3 AAA domain SMC_N PF02463.14 KFX93456.1 - 3.1e-11 42.9 3.8 0.00075 18.7 0.0 4.7 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX93456.1 - 2.3e-09 38.1 0.1 0.0029 18.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KFX93456.1 - 4.8e-07 29.5 0.3 0.15 11.7 0.2 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KFX93456.1 - 8.5e-07 29.1 0.0 0.021 14.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFX93456.1 - 1.1e-06 29.1 0.4 0.0056 17.1 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 KFX93456.1 - 3.2e-06 26.5 0.2 0.087 12.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX93456.1 - 1.3e-05 25.2 1.6 0.024 14.6 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFX93456.1 - 1.4e-05 24.3 0.0 0.064 12.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KFX93456.1 - 1.7e-05 25.1 2.7 0.32 11.3 0.0 3.9 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 KFX93456.1 - 2.2e-05 24.3 0.0 0.18 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KFX93456.1 - 6e-05 22.6 0.5 0.93 8.8 0.1 3.8 3 1 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 KFX93456.1 - 6.2e-05 22.9 0.0 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_15 PF13175.1 KFX93456.1 - 6.5e-05 22.1 11.2 0.35 9.8 0.1 5.1 4 2 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFX93456.1 - 0.00015 21.9 3.3 0.93 9.7 0.1 4.3 5 1 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KFX93456.1 - 0.00019 21.8 16.5 0.03 14.6 0.0 4.6 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 KFX93456.1 - 0.00023 20.8 0.2 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 KFX93456.1 - 0.00046 19.6 0.0 1.1 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX93456.1 - 0.00061 19.6 0.6 2 8.3 0.0 3.3 5 0 0 5 5 2 2 AAA domain RNA_helicase PF00910.17 KFX93456.1 - 0.0019 18.3 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 KFX93456.1 - 0.0033 16.2 2.2 0.92 8.2 0.0 3.0 3 1 1 4 4 4 2 ArgK protein Zeta_toxin PF06414.7 KFX93456.1 - 0.0034 16.5 0.0 0.49 9.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.18 KFX93456.1 - 0.0035 17.1 5.0 2.3 8.0 0.0 4.0 4 0 0 4 4 4 1 Dynamin family SbcCD_C PF13558.1 KFX93456.1 - 0.004 17.0 0.2 2.3 8.1 0.1 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 KFX93456.1 - 0.0046 16.6 0.1 1.2 8.8 0.0 2.9 3 0 0 3 3 2 1 NTPase AAA_28 PF13521.1 KFX93456.1 - 0.0061 16.5 8.0 0.25 11.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.1 KFX93456.1 - 0.013 15.0 0.1 5 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KFX93456.1 - 0.021 14.3 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 KFX93456.1 - 0.023 14.4 0.1 3.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain NB-ARC PF00931.17 KFX93456.1 - 0.03 13.2 0.1 5.6 5.7 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.9 KFX93456.1 - 0.041 13.6 0.6 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.14 KFX93456.1 - 0.043 13.2 3.5 1.9 7.8 0.5 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KFX93456.1 - 0.072 12.5 0.1 14 5.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KFX93456.1 - 0.26 11.0 10.2 1.3 8.7 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function DUF87 GSDH PF07995.6 KFX93459.1 - 3.4e-05 23.0 0.1 7.5e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase F-box-like PF12937.2 KFX93460.1 - 0.00013 21.5 0.3 0.00029 20.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like Mating_C PF12737.2 KFX93460.1 - 0.014 14.3 13.9 0.021 13.7 9.6 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DDE_Tnp_4 PF13359.1 KFX93460.1 - 0.17 11.4 0.4 1.1 8.9 0.1 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease WD40 PF00400.27 KFX93461.1 - 5.9e-28 95.7 9.7 6.1e-13 48.1 0.2 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFX93461.1 - 0.054 13.2 6.5 0.028 14.1 0.8 2.2 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term SPRY PF00622.23 KFX93462.1 - 4.6e-21 75.1 0.0 6.9e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain BPD_transp_2 PF02653.11 KFX93462.1 - 0.023 13.6 1.0 0.034 13.1 0.7 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component zf-C3HC4 PF00097.20 KFX93470.1 - 0.15 11.7 7.2 0.32 10.6 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.9 KFX93479.1 - 7.9e-27 93.3 0.1 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KFX93479.1 - 4.5e-14 52.4 1.6 4.5e-14 52.4 1.1 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KFX93479.1 - 7.2e-05 22.1 0.1 0.00011 21.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 KFX93479.1 - 0.024 13.9 5.6 0.043 13.2 3.9 1.6 1 1 0 1 1 1 0 NnrU protein Cupin_2 PF07883.6 KFX93506.1 - 2.9e-15 55.5 0.6 5.1e-15 54.7 0.1 1.6 2 0 0 2 2 2 1 Cupin domain EutQ PF06249.7 KFX93506.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Zn_clus PF00172.13 KFX93507.1 - 5.7e-09 35.7 10.3 9.9e-09 34.9 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX93507.1 - 1.6e-05 23.8 0.0 3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 KFX93508.1 - 3.4e-29 101.7 0.2 4.6e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX93508.1 - 5e-19 69.0 0.1 7.4e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX93508.1 - 3.9e-08 33.0 0.1 2.3e-07 30.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KFX93508.1 - 4.5e-07 29.1 0.2 7.4e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KFX93508.1 - 8.1e-07 28.0 0.6 4e-06 25.7 0.1 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KFX93508.1 - 0.00067 19.5 0.3 0.0014 18.5 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KFX93508.1 - 0.0014 18.9 0.1 0.0038 17.5 0.1 1.8 2 0 0 2 2 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFX93508.1 - 0.0025 17.6 0.3 0.023 14.5 0.1 2.4 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.7 KFX93508.1 - 0.0037 16.2 0.0 0.0063 15.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KFX93508.1 - 0.013 14.4 0.1 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Formyl_trans_N PF00551.14 KFX93508.1 - 0.017 14.6 0.0 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 Formyl transferase DXP_reductoisom PF02670.11 KFX93508.1 - 0.033 14.7 0.7 0.11 13.0 0.1 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TrkA_N PF02254.13 KFX93508.1 - 0.041 13.8 1.9 0.054 13.4 0.3 2.0 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.12 KFX93508.1 - 0.045 14.1 2.6 0.18 12.2 0.4 2.5 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KFX93508.1 - 0.057 12.3 0.4 0.78 8.5 0.1 2.4 1 1 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 KFX93508.1 - 0.084 13.1 0.2 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX93508.1 - 0.1 11.7 0.1 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Transferase PF02458.10 KFX93509.1 - 0.0029 16.1 0.0 0.026 12.9 0.0 2.0 1 1 0 1 1 1 1 Transferase family Abhydrolase_3 PF07859.8 KFX93510.1 - 4.2e-12 46.1 0.1 1.3e-05 24.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX93510.1 - 3e-07 29.4 0.0 0.01 14.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) La PF05383.12 KFX93511.1 - 8.2e-18 63.9 0.3 1.8e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 La domain CwfJ_C_1 PF04677.10 KFX93518.1 - 6.7e-28 96.8 0.0 1.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KFX93518.1 - 5.2e-27 94.2 0.0 2.6e-26 91.9 0.0 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 SET_assoc PF11767.3 KFX93518.1 - 0.09 12.0 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated ATP_bind_1 PF03029.12 KFX93519.1 - 1.5e-76 257.1 0.0 1.9e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KFX93519.1 - 5.2e-06 26.0 0.0 0.00017 21.0 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KFX93519.1 - 7.9e-06 24.8 0.0 0.011 14.5 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KFX93519.1 - 0.00015 21.9 0.0 0.0005 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX93519.1 - 0.00019 20.9 0.1 0.00033 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 KFX93519.1 - 0.00028 21.3 0.0 0.43 11.0 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein SRP54 PF00448.17 KFX93519.1 - 0.00039 19.9 0.0 0.017 14.5 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KFX93519.1 - 0.00075 19.3 0.1 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX93519.1 - 0.00077 19.3 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KFX93519.1 - 0.001 19.8 0.1 0.0083 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFX93519.1 - 0.0012 18.4 0.0 0.0049 16.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PRK PF00485.13 KFX93519.1 - 0.0022 17.5 0.0 0.0077 15.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.13 KFX93519.1 - 0.0026 17.0 0.0 0.077 12.2 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.16 KFX93519.1 - 0.0038 16.4 0.0 0.83 8.8 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_16 PF13191.1 KFX93519.1 - 0.0044 17.0 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 KFX93519.1 - 0.0067 15.8 0.5 0.021 14.2 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 KFX93519.1 - 0.0084 14.8 0.2 0.55 8.8 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit NB-ARC PF00931.17 KFX93519.1 - 0.011 14.5 0.3 0.026 13.3 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KFX93519.1 - 0.014 14.8 0.0 0.67 9.3 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFX93519.1 - 0.015 15.0 0.1 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFX93519.1 - 0.016 14.7 0.0 0.2 11.1 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KFX93519.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFX93519.1 - 0.024 13.7 0.0 0.057 12.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Methyltransf_32 PF13679.1 KFX93519.1 - 0.094 12.4 0.0 0.53 9.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain AAA_18 PF13238.1 KFX93519.1 - 0.61 10.4 0.0 0.61 10.4 0.0 2.8 3 1 1 4 4 3 0 AAA domain HEAT_2 PF13646.1 KFX93533.1 - 2.6e-13 50.0 0.3 1.2e-06 28.6 0.0 1.8 1 1 1 2 2 2 2 HEAT repeats Fes1 PF08609.5 KFX93533.1 - 3.6e-11 43.3 3.0 3.6e-11 43.3 2.1 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.18 KFX93533.1 - 6e-08 32.2 0.0 0.017 14.9 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFX93533.1 - 4.2e-06 26.3 0.1 0.0078 16.2 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 KFX93533.1 - 2.4e-05 24.6 0.1 0.2 12.2 0.0 2.6 2 0 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.15 KFX93533.1 - 0.057 11.7 0.1 5.7 5.1 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Ribosomal_L5_C PF00673.16 KFX93534.1 - 2.9e-22 78.2 0.0 4.9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFX93534.1 - 1.2e-11 44.1 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 MIF4G_like PF09088.6 KFX93535.1 - 9.1e-84 279.6 0.0 1.4e-83 279.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KFX93535.1 - 9e-51 172.5 0.0 1.6e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KFX93535.1 - 0.0006 19.2 0.0 0.0028 17.0 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain 6PF2K PF01591.13 KFX93536.1 - 5.2e-57 192.4 0.0 7.2e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFX93536.1 - 1.6e-24 86.8 0.2 2.5e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KFX93536.1 - 9.2e-07 29.7 0.1 0.0002 22.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX93536.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFX93536.1 - 0.027 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KFX93536.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 KFX93536.1 - 0.085 12.5 0.0 0.69 9.5 0.0 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 KFX93536.1 - 0.091 11.9 0.0 0.27 10.4 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Porin_3 PF01459.17 KFX93537.1 - 1.2e-86 290.3 0.3 1.4e-86 290.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2181 PF10223.4 KFX93544.1 - 0.053 12.8 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) EMP24_GP25L PF01105.19 KFX93545.1 - 1.2e-41 142.4 0.0 1.3e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 KFX93545.1 - 0.016 13.4 0.9 0.021 13.0 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 KFX93545.1 - 0.18 12.1 0.8 0.53 10.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) PhyH PF05721.8 KFX93551.1 - 2.8e-12 47.1 0.0 4.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.19 KFX93566.1 - 4.4e-92 309.0 26.3 5.4e-92 308.7 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93566.1 - 6.1e-16 58.0 47.4 1.9e-11 43.2 23.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 KFX93566.1 - 0.051 13.5 0.5 0.051 13.5 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) ADK PF00406.17 KFX93574.1 - 6.2e-26 91.0 0.0 1.6e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KFX93574.1 - 2e-10 40.1 0.0 4.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid A_deamin PF02137.13 KFX93582.1 - 6.5e-65 219.6 0.0 7.8e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2203 PF09969.4 KFX93583.1 - 1.6 8.9 4.8 1.1 9.4 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Conotoxin PF02950.12 KFX93583.1 - 4.8 8.0 12.4 0.23 12.2 1.8 3.0 3 0 0 3 3 3 0 Conotoxin SF3b10 PF07189.6 KFX93584.1 - 8.6e-39 131.2 0.0 1.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 KFX93585.1 - 5.8e-42 143.2 0.0 8e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 MAGE family MFS_1 PF07690.11 KFX93586.1 - 2.8e-32 111.8 28.6 4.3e-32 111.1 19.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Rad21_Rec8_N PF04825.8 KFX93586.1 - 2.6e-29 101.4 0.0 4.7e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KFX93586.1 - 2.5e-05 23.3 0.0 5.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TRP PF06011.7 KFX93587.1 - 3.8e-101 338.8 22.1 6.6e-101 338.0 15.3 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFX93587.1 - 1.2e-09 38.3 0.0 3.5e-09 36.8 0.0 1.7 1 1 1 2 2 2 1 ML-like domain BTB PF00651.26 KFX93588.1 - 2.8e-30 104.5 0.1 8.4e-15 54.7 0.4 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.1 KFX93588.1 - 2.9e-07 30.4 0.0 6.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFX93588.1 - 4.9e-07 29.2 0.4 2.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KFX93588.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX93588.1 - 3.6e-05 24.1 0.1 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93588.1 - 0.0012 18.8 0.0 0.0046 17.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Imm41 PF15583.1 KFX93588.1 - 0.022 14.5 3.8 0.12 12.1 2.6 2.1 1 1 0 1 1 1 0 Immunity protein 41 DUF3342 PF11822.3 KFX93588.1 - 0.033 13.3 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase PF00069.20 KFX93589.1 - 3e-58 197.0 0.0 4.4e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93589.1 - 7.4e-36 123.5 0.0 1.5e-25 89.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX93589.1 - 0.00019 20.5 0.0 0.00038 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 KFX93589.1 - 0.0014 17.6 0.0 0.0055 15.6 0.0 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 APH PF01636.18 KFX93589.1 - 0.14 11.8 0.7 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family EURL PF06937.6 KFX93589.1 - 1.8 7.9 6.6 3.4 7.0 4.6 1.3 1 0 0 1 1 1 0 EURL protein 4HBT_3 PF13622.1 KFX93591.1 - 5.8e-51 173.6 0.3 8.2e-51 173.1 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFX93591.1 - 4.7e-26 90.9 0.0 1.9e-10 40.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase AfsA PF03756.8 KFX93591.1 - 0.14 11.8 0.6 0.35 10.6 0.4 1.6 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain MT0933_antitox PF14013.1 KFX93592.1 - 0.4 10.8 4.1 0.8 9.8 2.9 1.5 1 0 0 1 1 1 0 MT0933-like antitoxin protein Oxysterol_BP PF01237.13 KFX93593.1 - 1.4e-129 431.6 0.4 5e-129 429.8 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.6 KFX93593.1 - 1.5e-35 121.7 0.1 3.5e-35 120.6 0.1 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_2 PF12796.2 KFX93593.1 - 1.2e-17 63.9 0.1 1.7e-11 44.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93593.1 - 5.1e-17 60.7 0.4 2.1e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFX93593.1 - 2.5e-16 59.3 0.6 1.4e-08 34.6 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX93593.1 - 9.4e-16 57.8 0.1 7.5e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) GAT PF03127.9 KFX93593.1 - 3.8e-14 52.4 1.1 3.8e-13 49.2 0.2 2.6 2 0 0 2 2 2 1 GAT domain Ank_3 PF13606.1 KFX93593.1 - 5.1e-12 44.8 0.1 0.0044 17.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 KFX93593.1 - 2.2e-11 43.8 0.6 6e-11 42.4 0.4 1.8 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KFX93593.1 - 4e-07 30.0 1.2 1.3e-06 28.4 0.5 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1886 PF09171.5 KFX93593.1 - 0.015 14.2 0.1 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) Shigella_OspC PF06128.6 KFX93593.1 - 0.39 10.1 0.0 1.8 8.0 0.0 1.9 2 0 0 2 2 2 0 Shigella flexneri OspC protein UBA_4 PF14555.1 KFX93594.1 - 4.4e-11 42.1 0.3 9e-11 41.1 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KFX93594.1 - 1.5e-09 37.7 0.0 3.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain Phage_Mu_F PF04233.9 KFX93594.1 - 1.1 9.7 6.5 2.7 8.5 4.5 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein Macoilin PF09726.4 KFX93594.1 - 6.4 4.9 12.5 9.2 4.3 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KFX93595.1 - 0.00019 20.6 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MGC-24 PF05283.6 KFX93595.1 - 0.025 14.3 4.5 0.055 13.2 3.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) BCAS2 PF05700.6 KFX93596.1 - 0.01 15.3 2.2 0.012 15.1 1.5 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3824 PF12868.2 KFX93596.1 - 0.12 13.3 1.1 0.14 13.0 0.2 1.5 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) tRNA-synt_2 PF00152.15 KFX93601.1 - 1.6e-36 125.7 0.0 1.8e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ADH_zinc_N PF00107.21 KFX93603.1 - 1.3e-18 66.8 0.3 2.9e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX93603.1 - 8e-15 55.8 0.1 1.9e-14 54.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX93603.1 - 2.9e-11 43.0 0.0 7.6e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFX93603.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding CENP-S PF15630.1 KFX93604.1 - 1.3e-34 118.1 0.0 2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KFX93604.1 - 0.00031 20.4 0.0 0.00092 18.8 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated CENP-T PF15511.1 KFX93604.1 - 0.00042 19.6 0.0 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 KFX93604.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFX93604.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.11 KFX93604.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SAM_decarbox PF01536.11 KFX93610.1 - 6.7e-55 186.0 0.0 7.6e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Bud13 PF09736.4 KFX93617.1 - 6.9e-19 68.5 0.3 6.9e-19 68.5 0.2 2.6 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF904 PF06005.7 KFX93617.1 - 0.039 14.2 0.1 0.039 14.2 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Hom_end_hint PF05203.11 KFX93617.1 - 0.99 9.0 3.7 0.4 10.3 0.6 1.9 2 0 0 2 2 2 0 Hom_end-associated Hint HALZ PF02183.13 KFX93617.1 - 2.9 7.6 10.1 9.9 5.9 1.5 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper FtsL PF04999.8 KFX93617.1 - 9.1 6.0 11.7 1.8 8.3 0.1 3.3 3 1 1 4 4 4 0 Cell division protein FtsL AAA_17 PF13207.1 KFX93618.1 - 0.00055 20.7 0.0 0.00055 20.7 0.0 3.1 3 1 1 4 4 4 1 AAA domain T2SE PF00437.15 KFX93618.1 - 0.0016 17.3 0.1 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 KFX93618.1 - 0.011 15.9 6.7 0.028 14.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain PRK PF00485.13 KFX93618.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KFX93618.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RE_TaqI PF09573.5 KFX93618.1 - 0.073 12.1 0.2 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 TaqI restriction endonuclease MobB PF03205.9 KFX93618.1 - 0.13 12.0 0.2 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFX93618.1 - 0.15 12.3 0.1 0.9 9.8 0.1 2.1 2 0 0 2 2 2 0 ABC transporter Lipase_3 PF01764.20 KFX93619.1 - 0.0027 17.3 0.0 0.044 13.4 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) PUA_2 PF14306.1 KFX93635.1 - 1.2e-52 177.5 0.0 1.3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 PUA-like domain bPH_6 PF10756.4 KFX93635.1 - 0.022 14.6 0.1 0.19 11.6 0.1 2.1 1 1 1 2 2 2 0 Bacterial PH domain Complex1_LYR_1 PF13232.1 KFX93636.1 - 1e-19 70.5 5.1 1.3e-19 70.1 3.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX93636.1 - 1.3e-18 66.5 4.3 1.9e-18 66.0 3.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KFX93636.1 - 0.0072 16.7 2.1 0.0085 16.5 1.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like ADH_zinc_N PF00107.21 KFX93638.1 - 1.3e-31 108.8 0.2 2e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX93638.1 - 5.7e-15 56.3 0.7 9.2e-15 55.6 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX93638.1 - 0.00028 20.6 0.3 0.011 15.5 0.1 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 KFX93638.1 - 0.039 13.8 1.3 0.066 13.1 0.9 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAM-associated PF14303.1 KFX93658.1 - 0.017 15.4 4.0 0.021 15.1 2.8 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4591 PF15261.1 KFX93658.1 - 0.14 12.3 6.0 0.23 11.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) DUF342 PF03961.8 KFX93658.1 - 0.16 10.3 2.9 0.17 10.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2937 PF11157.3 KFX93658.1 - 0.37 10.0 2.1 0.5 9.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF4355 PF14265.1 KFX93658.1 - 0.39 10.6 9.1 0.64 9.9 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) bZIP_2 PF07716.10 KFX93658.1 - 4.1 7.2 16.6 0.06 13.1 5.0 2.1 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 KFX93658.1 - 4.8 6.7 12.2 3.1 7.3 2.0 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 KFX93660.1 - 0.028 14.2 3.4 0.028 14.2 2.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper HJURP_mid PF12346.3 KFX93660.1 - 0.075 13.1 0.9 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat FAM177 PF14774.1 KFX93660.1 - 0.11 12.4 3.5 0.088 12.7 1.2 1.7 1 1 1 2 2 2 0 FAM177 family Phlebovirus_NSM PF07246.6 KFX93660.1 - 0.15 11.1 5.7 0.19 10.8 4.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4051 PF13260.1 KFX93660.1 - 0.38 10.1 1.4 0.46 9.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4051) DUF342 PF03961.8 KFX93660.1 - 0.59 8.4 3.4 0.64 8.3 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 KFX93660.1 - 4.2 6.9 10.8 1.9 8.0 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator RVT_1 PF00078.22 KFX93667.1 - 3.4e-05 23.2 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ZZ PF00569.12 KFX93669.1 - 2.3e-12 46.2 7.0 3.7e-12 45.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KFX93669.1 - 2e-07 29.8 14.2 2.7e-05 23.1 0.4 3.9 5 0 0 5 5 5 2 EF hand EF-hand_7 PF13499.1 KFX93669.1 - 5.1e-07 29.7 2.9 0.0031 17.6 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KFX93669.1 - 1.7e-05 24.2 9.0 0.00022 20.8 0.6 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFX93669.1 - 0.001 18.6 7.0 0.031 13.9 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair C1_3 PF07649.7 KFX93669.1 - 0.023 14.7 5.2 0.038 14.0 3.6 1.4 1 0 0 1 1 1 0 C1-like domain zf-B_box PF00643.19 KFX93669.1 - 0.092 12.6 5.5 0.17 11.7 3.8 1.4 1 0 0 1 1 1 0 B-box zinc finger Diphthamide_syn PF01866.12 KFX93671.1 - 1.3e-52 178.9 0.0 1.4e-51 175.5 0.0 1.9 2 0 0 2 2 2 1 Putative diphthamide synthesis protein RTA1 PF04479.8 KFX93672.1 - 4.9e-52 176.6 6.3 7.2e-52 176.1 4.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Sec62 PF03839.11 KFX93672.1 - 5.2 6.4 5.3 0.45 9.8 0.1 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 Zn_clus PF00172.13 KFX93673.1 - 7.4e-08 32.1 10.7 1.5e-07 31.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX93673.1 - 0.031 12.8 0.2 0.047 12.2 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 KFX93674.1 - 1.2e-20 74.4 0.1 2e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX93674.1 - 8.9e-14 51.5 0.0 1.4e-12 47.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX93674.1 - 7.4e-09 35.5 0.0 2.1e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX93674.1 - 0.0018 17.5 0.0 0.3 10.2 0.0 2.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Glyco_hydro_32N PF00251.15 KFX93674.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain UPF0227 PF05728.7 KFX93674.1 - 0.078 12.6 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.5 KFX93674.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 KFX93674.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Not3 PF04065.10 KFX93675.1 - 0.072 12.3 0.3 0.075 12.2 0.2 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Copper-fist PF00649.13 KFX93675.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain JSRP PF15312.1 KFX93675.1 - 0.17 11.8 0.5 0.36 10.8 0.1 1.7 1 1 1 2 2 2 0 Junctional sarcoplasmic reticulum protein Kelch_5 PF13854.1 KFX93676.1 - 6e-08 32.4 0.3 1.5e-07 31.2 0.2 4.0 4 0 0 4 4 4 2 Kelch motif VSP PF03302.8 KFX93676.1 - 0.0027 16.3 0.2 0.0042 15.7 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_gE PF02480.11 KFX93676.1 - 0.0083 14.4 0.0 0.011 13.9 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 KFX93676.1 - 0.12 11.9 0.2 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain FAD_binding_4 PF01565.18 KFX93678.1 - 1.2e-23 83.0 0.0 1.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX93678.1 - 0.0046 16.8 0.0 0.021 14.7 0.0 2.2 1 0 0 1 1 1 1 Berberine and berberine like COesterase PF00135.23 KFX93679.1 - 2.7e-64 217.8 0.1 4.6e-64 217.0 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX93679.1 - 9.7e-08 31.8 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX93679.1 - 0.022 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KFX93679.1 - 0.08 11.5 0.1 0.46 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Fungal_trans_2 PF11951.3 KFX93680.1 - 4.1e-06 25.6 0.4 5.4e-06 25.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1175 PF06672.6 KFX93681.1 - 0.0042 16.4 0.1 0.0073 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1175) Glyco_hydro_43 PF04616.9 KFX93682.1 - 4.2e-68 229.5 0.9 5.3e-68 229.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF897 PF05982.7 KFX93690.1 - 6.6 5.4 23.4 19 3.9 16.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF897) Collagen PF01391.13 KFX93701.1 - 0.041 13.4 5.6 0.085 12.4 3.9 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF2890 PF11081.3 KFX93701.1 - 0.05 13.6 0.7 0.063 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) zf-C2H2_4 PF13894.1 KFX93712.1 - 0.025 14.8 0.1 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Lyase_1 PF00206.15 KFX93722.1 - 3.5e-59 200.5 0.0 4.1e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Lyase GHMP_kinases_N PF00288.21 KFX93723.1 - 0.025 14.6 0.2 0.082 12.9 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain Chitin_bind_3 PF03067.10 KFX93724.1 - 0.02 15.1 0.0 0.059 13.6 0.0 1.7 1 1 0 1 1 1 0 Chitin binding domain Cu-oxidase_2 PF07731.9 KFX93725.1 - 6.3e-25 87.2 1.0 9.6e-24 83.4 0.5 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFX93725.1 - 8.8e-24 83.5 0.5 3.1e-23 81.7 0.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KFX93725.1 - 0.0043 16.9 0.0 0.43 10.4 0.0 2.8 2 1 0 2 2 2 1 Multicopper oxidase Zn_clus PF00172.13 KFX93726.1 - 2.5e-05 24.0 9.3 4.2e-05 23.3 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40_alt PF14077.1 KFX93726.1 - 0.052 13.1 0.3 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif RTA1 PF04479.8 KFX93728.1 - 1.6e-34 119.3 8.4 2.1e-34 118.9 5.8 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3902 PF13042.1 KFX93728.1 - 1.7 7.8 9.2 0.14 11.4 2.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3902) DUF3671 PF12420.3 KFX93728.1 - 9.7 6.2 20.6 0.67 9.9 5.8 2.9 2 1 1 3 3 3 0 Protein of unknown function AMP-binding PF00501.23 KFX93729.1 - 0 1087.5 0.0 9.1e-85 284.5 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KFX93729.1 - 4.6e-173 574.0 0.0 1.7e-47 161.7 0.0 5.3 5 0 0 5 5 5 5 Condensation domain p450 PF00067.17 KFX93729.1 - 4.7e-54 183.6 0.0 8e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.20 KFX93729.1 - 5.4e-44 148.3 4.6 4.2e-11 42.9 0.0 5.7 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX93729.1 - 1.8e-18 67.2 0.0 0.0017 19.2 0.0 5.0 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain Chromo PF00385.19 KFX93729.1 - 7.7e-07 28.6 1.1 1.8e-06 27.5 0.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Defensin_beta_2 PF13841.1 KFX93729.1 - 6.2 7.2 0.1 14 6.0 0.0 1.6 1 0 0 1 1 1 0 Beta defensin AATase PF07247.7 KFX93730.1 - 1.6e-12 46.7 0.0 1.1e-08 34.1 0.0 3.0 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 KFX93730.1 - 0.02 13.7 0.2 0.17 10.6 0.0 2.6 2 1 0 2 2 2 0 Condensation domain DIOX_N PF14226.1 KFX93731.1 - 5.6e-23 81.6 0.0 9.9e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX93731.1 - 4.1e-07 30.2 0.0 8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorA PF01544.13 KFX93732.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Glucokinase PF02685.11 KFX93732.1 - 0.038 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucokinase Glyco_hydro_7 PF00840.15 KFX93735.1 - 3.8e-207 687.8 24.8 4.3e-207 687.6 17.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Alginate_lyase2 PF08787.6 KFX93736.1 - 1.1e-42 146.3 0.0 1.2e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Laminin_G_3 PF13385.1 KFX93736.1 - 0.03 14.5 1.2 0.053 13.7 0.8 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Alginate_lyase PF05426.7 KFX93738.1 - 1e-12 48.0 3.1 1.2e-11 44.4 2.2 2.1 1 1 0 1 1 1 1 Alginate lyase Cerato-platanin PF07249.7 KFX93739.1 - 3.1e-47 159.4 0.9 3.6e-47 159.2 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Pkinase PF00069.20 KFX93740.1 - 5.9e-72 241.9 0.0 9.4e-72 241.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93740.1 - 3.1e-34 118.2 0.1 5.6e-33 114.1 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX93740.1 - 1.5e-05 24.1 0.0 2.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX93740.1 - 0.00044 20.0 0.2 0.0021 17.8 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX93740.1 - 0.00094 18.2 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX93740.1 - 0.0014 18.0 0.1 0.0035 16.7 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFX93740.1 - 0.0038 16.8 0.1 0.0074 15.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase SMC_N PF02463.14 KFX93741.1 - 4.8e-27 94.6 0.0 9.3e-27 93.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX93741.1 - 5.1e-15 56.3 13.9 5.1e-15 56.3 9.6 4.4 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX93741.1 - 4.3e-08 33.4 0.0 6e-05 23.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX93741.1 - 0.00028 20.3 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KFX93741.1 - 0.035 14.3 0.8 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KFX93741.1 - 0.44 10.8 0.0 0.44 10.8 0.0 4.6 3 2 0 3 3 3 0 ABC transporter Cyto_heme_lyase PF01265.12 KFX93753.1 - 1.5e-82 277.0 0.0 1.7e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase tRNA-synt_1g PF09334.6 KFX93754.1 - 4.6e-137 456.8 0.0 8.2e-137 456.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFX93754.1 - 1.4e-05 23.2 0.6 0.1 10.5 0.0 3.8 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.2 KFX93754.1 - 1.3 8.8 5.6 3.4 7.5 3.0 1.8 1 1 1 2 2 2 0 Double zinc ribbon Yae1_N PF09811.4 KFX93755.1 - 1.5e-08 34.0 5.3 2.4e-08 33.3 3.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Glyco_hydro_7 PF00840.15 KFX93759.1 - 8.5e-134 446.1 9.8 3.7e-132 440.7 6.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_20 PF00686.14 KFX93760.1 - 9.4e-32 108.4 0.9 1.6e-31 107.7 0.6 1.4 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KFX93760.1 - 1.6e-09 38.2 1.1 9.9e-07 29.1 0.2 2.7 2 1 0 2 2 2 1 Chitin binding domain PAD PF03068.10 KFX93763.1 - 6.5e-47 159.7 0.0 4e-46 157.1 0.0 2.0 1 1 0 1 1 1 1 Protein-arginine deiminase (PAD) Fungal_trans_2 PF11951.3 KFX93765.1 - 3.6e-30 104.8 3.4 4.6e-30 104.4 2.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93765.1 - 5.3e-05 23.0 8.8 0.00011 22.0 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 KFX93766.1 - 1.7e-12 47.0 0.0 2.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX93766.1 - 6.2e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX93766.1 - 0.0071 16.2 0.1 0.018 14.9 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KFX93766.1 - 0.026 13.3 0.2 3.1 6.4 0.1 2.1 2 0 0 2 2 2 0 ArgK protein DUF258 PF03193.11 KFX93766.1 - 0.054 12.6 0.2 0.093 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFX93766.1 - 0.07 13.9 0.3 0.14 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 KFX93766.1 - 0.13 11.4 0.0 0.54 9.4 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.1 KFX93766.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AA_permease_2 PF13520.1 KFX93767.1 - 8.9e-78 261.7 27.1 1.2e-77 261.2 18.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX93767.1 - 2.3e-15 55.9 25.6 2.9e-15 55.5 17.7 1.1 1 0 0 1 1 1 1 Amino acid permease Lipase_GDSL PF00657.17 KFX93769.1 - 6.2e-05 22.9 6.6 9.8e-05 22.2 4.6 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF778 PF05608.7 KFX93769.1 - 0.046 13.6 0.1 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF778) LRR_adjacent PF08191.6 KFX93769.1 - 4 7.2 5.9 13 5.5 0.1 2.7 3 0 0 3 3 3 0 LRR adjacent AA_permease_2 PF13520.1 KFX93770.1 - 3.3e-52 177.4 55.3 4e-52 177.1 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX93770.1 - 1.2e-18 66.7 43.2 1.5e-18 66.4 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.15 KFX93771.1 - 1.5e-166 554.2 0.0 2e-166 553.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFX93771.1 - 1.8e-19 69.6 0.0 4.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFX93771.1 - 3.8e-14 52.5 0.1 8.7e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain FSH1 PF03959.8 KFX93772.1 - 6.5e-24 84.5 0.0 2.8e-23 82.4 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) IucA_IucC PF04183.7 KFX93773.1 - 1.2e-21 77.1 0.1 1.7e-17 63.5 0.1 2.3 2 0 0 2 2 2 2 IucA / IucC family FhuF PF06276.7 KFX93773.1 - 1.8e-18 67.0 0.0 3.2e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter TauD PF02668.11 KFX93774.1 - 4.4e-32 111.7 0.0 5.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFX93774.1 - 0.0086 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 CsiD Peptidase_S8 PF00082.17 KFX93775.1 - 3.4e-52 177.3 10.1 4.8e-52 176.8 7.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFX93775.1 - 1.8e-10 41.2 0.6 3.6e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SNF2_N PF00176.18 KFX93776.1 - 6.4e-63 212.3 0.0 1.1e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX93776.1 - 2.2e-10 40.2 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KFX93776.1 - 6.2e-06 25.7 6.8 1.2e-05 24.8 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX93776.1 - 8.1e-06 25.4 4.5 8.1e-06 25.4 3.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX93776.1 - 1.2e-05 24.9 6.3 2.4e-05 23.9 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX93776.1 - 2e-05 24.5 6.5 2e-05 24.5 4.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX93776.1 - 5.2e-05 23.0 7.5 0.00012 21.9 5.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFX93776.1 - 7e-05 22.5 6.8 0.00016 21.4 4.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KFX93776.1 - 0.00096 18.8 0.6 0.0021 17.8 0.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KFX93776.1 - 0.0088 15.5 6.0 0.041 13.4 4.2 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 KFX93776.1 - 0.024 14.3 1.4 0.071 12.8 0.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger adh_short PF00106.20 KFX93777.1 - 1.9e-14 53.9 0.0 5.6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX93777.1 - 6.4e-08 32.4 0.0 2.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFX93777.1 - 3.4e-06 26.6 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFX93777.1 - 1.1e-05 25.4 0.0 3e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFX93777.1 - 0.016 15.2 0.4 0.06 13.3 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding G-patch PF01585.18 KFX93778.1 - 7.9e-11 41.5 0.2 2e-10 40.2 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFX93778.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site PRK PF00485.13 KFX93779.1 - 3.5e-56 189.8 0.0 7.1e-56 188.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KFX93779.1 - 4.9e-40 136.9 0.0 9.4e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KFX93779.1 - 1.2e-06 29.3 0.0 1.2e-06 29.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain CPT PF07931.7 KFX93779.1 - 1.2e-05 24.9 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KFX93779.1 - 0.00014 22.1 0.0 0.00014 22.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX93779.1 - 0.003 17.4 0.0 0.033 14.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KFX93779.1 - 0.014 15.7 0.5 0.056 13.7 0.1 2.1 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 KFX93779.1 - 0.024 13.7 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 KFX93779.1 - 0.053 12.4 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 KFX93779.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KFX93779.1 - 0.057 13.3 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFX93779.1 - 0.084 12.8 0.4 0.23 11.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Kei1 PF08552.6 KFX93780.1 - 6.1e-57 192.3 4.7 7.6e-57 192.0 3.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Nop53 PF07767.6 KFX93781.1 - 7.9e-103 344.4 25.6 1.1e-102 344.0 17.8 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Spore_YhcN_YlaJ PF09580.5 KFX93781.1 - 0.0063 16.6 5.5 0.014 15.4 3.8 1.5 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ras PF00071.17 KFX93782.1 - 2.2e-59 199.4 0.3 2.9e-59 199.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX93782.1 - 1.3e-20 74.0 0.2 2.2e-20 73.3 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFX93782.1 - 6.9e-18 64.4 0.2 8.4e-18 64.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX93782.1 - 1.5e-07 31.0 0.0 7e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFX93782.1 - 5.5e-06 25.6 0.3 7e-06 25.3 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX93782.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX93782.1 - 3.8e-05 22.9 0.0 7.1e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFX93782.1 - 0.029 14.1 0.1 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 KFX93782.1 - 0.065 13.3 0.0 1.9 8.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 KFX93782.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX93782.1 - 0.12 12.2 0.0 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFX93782.1 - 0.13 11.9 0.2 4 7.1 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NIR_SIR PF01077.17 KFX93783.1 - 5e-53 178.6 0.2 7.5e-46 155.3 0.1 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KFX93783.1 - 4.2e-30 103.1 0.1 1.7e-14 53.2 0.0 3.1 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KFX93783.1 - 8.4e-25 87.4 0.0 1.7e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KFX93783.1 - 1.5e-07 31.1 0.1 3.9e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg F1F0-ATPsyn_F PF10791.4 KFX93785.1 - 3.6e-42 142.4 0.4 4.3e-42 142.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KFX93785.1 - 0.00019 21.4 0.2 0.00026 20.9 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 KFX93786.1 - 5.9e-37 125.5 1.0 5.9e-37 125.5 0.7 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region Aminotran_1_2 PF00155.16 KFX93787.1 - 1.8e-21 76.4 0.0 2.4e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFX93787.1 - 0.001 17.7 0.0 0.0071 14.9 0.0 2.2 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase MCM PF00493.18 KFX93788.1 - 2.2e-136 454.0 0.6 3.5e-136 453.3 0.4 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFX93788.1 - 5.8e-22 78.4 0.4 2.3e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFX93788.1 - 7e-08 31.8 0.0 8.4e-07 28.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFX93788.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KFX93788.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX93788.1 - 0.0067 16.1 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CDC27 PF09507.5 KFX93789.1 - 3e-81 273.8 15.2 3.6e-81 273.6 10.5 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 KFX93790.1 - 2.5e-177 589.7 0.0 2.9e-177 589.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) MOZ_SAS PF01853.13 KFX93791.1 - 1.2e-84 282.2 0.2 1.7e-84 281.7 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KFX93791.1 - 3.4e-18 65.0 0.0 1.4e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KFX93791.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_T PF00929.19 KFX93792.1 - 3e-27 95.9 0.0 4.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFX93792.1 - 2.4e-05 23.8 0.0 7.4e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease RNase_H2_suC PF08615.6 KFX93793.1 - 7.5e-22 77.6 0.0 1.4e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-C3HC4_3 PF13920.1 KFX93793.1 - 3.7e-07 29.7 13.8 2.6e-06 27.0 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX93793.1 - 5.1e-07 29.2 12.5 5.1e-07 29.2 8.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX93793.1 - 6.9e-07 28.8 14.7 1.3e-06 28.0 8.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX93793.1 - 9.8e-07 28.7 13.0 9.8e-07 28.7 9.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFX93793.1 - 2.9e-06 26.9 3.7 2.9e-06 26.9 2.5 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFX93793.1 - 5.1e-06 26.0 7.8 5.1e-06 26.0 5.4 2.8 3 0 0 3 3 3 1 RING-type zinc-finger U-box PF04564.10 KFX93793.1 - 8.4e-06 25.6 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 KFX93793.1 - 2.5e-05 24.0 15.8 5e-05 23.0 8.5 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFX93793.1 - 2.8e-05 23.8 16.2 5.5e-05 22.9 8.6 2.5 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.22 KFX93793.1 - 7.5e-05 22.1 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 SAP domain Stonin2_N PF12016.3 KFX93793.1 - 0.00058 19.1 0.1 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Stonin 2 zf-rbx1 PF12678.2 KFX93793.1 - 0.0036 17.3 7.2 0.0058 16.7 3.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 KFX93793.1 - 0.0045 16.5 8.3 0.0045 16.5 5.7 2.3 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF1455 PF07306.6 KFX93793.1 - 0.054 13.5 0.3 3.1 7.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) Mob_synth_C PF06463.8 KFX93793.1 - 0.29 10.8 3.1 0.7 9.5 2.1 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Snf7 PF03357.16 KFX93794.1 - 6.7e-19 67.8 12.9 1.4e-18 66.8 8.9 1.6 1 1 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 KFX93794.1 - 0.071 12.9 2.2 4.3 7.1 0.3 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.1 KFX93794.1 - 0.088 12.5 6.3 1 9.1 0.2 2.9 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF932 PF06067.6 KFX93794.1 - 0.19 11.0 6.0 2.9 7.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) MutS_III PF05192.13 KFX93794.1 - 0.82 9.4 5.4 0.88 9.3 2.3 2.0 1 1 1 2 2 2 0 MutS domain III TRAPPC-Trs85 PF12739.2 KFX93795.1 - 1e-116 390.0 0.0 1.4e-116 389.5 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.15 KFX93797.1 - 6.7e-25 87.7 0.1 1.3e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KFX93797.1 - 2.3e-05 23.8 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF2454 PF10521.4 KFX93798.1 - 5.9e-59 199.3 0.2 8.8e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT PF02985.17 KFX93798.1 - 0.044 13.8 0.0 0.19 11.9 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat DUF2435 PF10363.4 KFX93798.1 - 0.15 11.9 1.3 0.31 10.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Syja_N PF02383.13 KFX93799.1 - 4.2e-85 285.3 0.0 1.7e-83 280.0 0.0 2.5 1 1 0 1 1 1 1 SacI homology domain RRM_1 PF00076.17 KFX93800.1 - 1.9e-25 88.2 1.2 3.9e-13 48.8 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX93800.1 - 3e-17 62.3 0.2 4.5e-08 32.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX93800.1 - 5.8e-15 54.8 1.6 2.5e-10 40.0 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 KFX93800.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Calcipressin PF04847.7 KFX93800.1 - 0.11 12.0 0.2 0.11 12.0 0.1 2.0 2 1 0 2 2 2 0 Calcipressin DUF45 PF01863.12 KFX93800.1 - 0.18 11.5 1.3 0.25 11.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 ATP-synt_D PF01813.12 KFX93801.1 - 3.3e-65 219.3 2.2 4.2e-65 218.9 1.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 KFX93801.1 - 0.51 10.2 3.1 0.42 10.5 0.5 2.0 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Nup54 PF13874.1 KFX93801.1 - 0.72 9.5 3.5 3.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin PF02996.12 KFX93801.1 - 1.4 8.6 4.9 2.3 7.8 0.0 3.0 2 1 2 4 4 4 0 Prefoldin subunit Viral_P18 PF04521.8 KFX93801.1 - 1.6 8.1 5.9 10 5.5 0.5 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_14 PF13428.1 KFX93802.1 - 7.8e-12 44.7 6.0 0.95 10.2 0.0 9.7 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX93802.1 - 2.6e-11 43.2 0.1 2 8.4 0.0 7.2 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX93802.1 - 9.9e-08 31.5 0.8 0.62 9.7 0.0 6.8 8 0 0 8 8 7 1 TPR repeat TPR_15 PF13429.1 KFX93802.1 - 5e-07 29.0 1.8 0.00018 20.6 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93802.1 - 6.2e-06 26.4 0.1 0.043 14.1 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93802.1 - 7.5e-05 22.3 12.0 1.2 9.2 0.0 6.6 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93802.1 - 7.9e-05 23.2 8.0 0.004 17.7 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat Suf PF05843.9 KFX93802.1 - 8.7e-05 22.3 9.1 0.27 10.9 0.1 4.6 5 0 0 5 5 5 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.7 KFX93802.1 - 0.00014 21.6 10.4 0.67 9.7 0.1 6.3 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 KFX93802.1 - 0.00045 19.8 2.4 1.3 8.9 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 KFX93802.1 - 0.012 14.9 0.1 0.43 9.9 0.0 3.1 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_17 PF13431.1 KFX93802.1 - 0.013 15.6 1.7 0.67 10.2 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KFX93802.1 - 0.017 14.0 10.8 0.13 11.1 0.7 5.3 2 2 1 3 3 3 0 NRDE-2, necessary for RNA interference TPR_10 PF13374.1 KFX93802.1 - 0.019 14.8 2.9 22 5.1 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX93802.1 - 0.16 12.5 3.9 11 6.7 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat ABC_membrane PF00664.18 KFX93813.1 - 1.7e-80 270.3 20.8 7.7e-44 150.1 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX93813.1 - 6.6e-44 149.5 0.0 2.3e-28 99.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX93813.1 - 1e-13 51.0 0.7 2.8e-09 36.5 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX93813.1 - 7.4e-08 33.2 0.7 0.016 15.9 0.7 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX93813.1 - 9.2e-08 31.5 1.7 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KFX93813.1 - 3.4e-07 30.5 0.2 0.035 14.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFX93813.1 - 4.5e-07 30.0 3.7 0.022 14.8 0.2 3.8 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KFX93813.1 - 9.8e-07 28.3 0.2 0.042 13.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX93813.1 - 2.5e-06 26.7 0.1 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFX93813.1 - 3e-06 26.9 7.3 0.12 11.8 0.1 3.6 4 0 0 4 4 3 3 AAA-like domain AAA_16 PF13191.1 KFX93813.1 - 3.3e-06 27.1 0.9 0.042 13.8 0.1 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.1 KFX93813.1 - 1.5e-05 25.3 1.9 0.29 11.4 0.5 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KFX93813.1 - 0.00021 21.0 0.2 1.6 8.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KFX93813.1 - 0.0013 18.2 0.4 2.2 7.7 0.0 3.2 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_33 PF13671.1 KFX93813.1 - 0.0044 16.8 2.9 0.42 10.4 0.2 2.8 3 0 0 3 3 2 1 AAA domain ABC_ATPase PF09818.4 KFX93813.1 - 0.0051 15.4 0.5 0.024 13.2 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 KFX93813.1 - 0.0073 15.4 0.1 4.1 6.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KFX93813.1 - 0.0081 16.3 0.1 2.5 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 KFX93813.1 - 0.0087 15.7 5.1 0.41 10.4 0.4 3.4 3 0 0 3 3 3 1 Part of AAA domain DUF3987 PF13148.1 KFX93813.1 - 0.019 13.5 0.1 2.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) T2SE PF00437.15 KFX93813.1 - 0.022 13.6 0.4 4 6.2 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 KFX93813.1 - 0.027 14.1 1.2 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.1 KFX93813.1 - 0.029 14.4 0.0 3.4 7.7 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KFX93813.1 - 0.031 13.7 1.0 3.2 7.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 KFX93813.1 - 0.031 14.2 1.9 0.76 9.7 0.2 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 KFX93813.1 - 0.032 13.7 0.6 7.3 6.0 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 KFX93813.1 - 0.049 12.5 0.0 8.6 5.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.1 KFX93813.1 - 0.053 11.9 1.4 0.48 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFX93813.1 - 0.062 13.6 4.4 0.24 11.7 0.3 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFX93813.1 - 0.063 12.9 2.3 0.72 9.5 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 KFX93813.1 - 0.066 12.6 0.4 13 5.2 0.2 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.16 KFX93813.1 - 0.086 11.9 0.1 1.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFX93813.1 - 0.14 11.7 1.8 7.7 6.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 KFX93813.1 - 0.24 10.6 5.7 7.9 5.6 0.1 3.5 4 0 0 4 4 4 0 PhoH-like protein AAA_24 PF13479.1 KFX93813.1 - 0.32 10.5 2.6 1.4 8.4 0.4 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KFX93813.1 - 0.36 10.6 6.8 5.1 6.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Polysacc_synt_4 PF04669.8 KFX93815.1 - 1.1e-25 90.1 1.4 5.8e-25 87.7 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.4 KFX93815.1 - 0.015 14.3 0.6 0.017 14.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Peroxin-22 PF12827.2 KFX93815.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family Sugar_tr PF00083.19 KFX93820.1 - 1.6e-127 425.8 26.5 1.9e-127 425.5 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93820.1 - 2.4e-21 75.8 41.0 9.4e-18 64.0 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_capsid PF06112.6 KFX93820.1 - 1.5 8.8 4.7 3.8 7.5 3.3 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Metallophos PF00149.23 KFX93821.1 - 3.4e-15 55.9 0.1 6.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 KFX93822.1 - 6.4e-85 284.7 0.0 1e-84 284.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX93822.1 - 2.6e-72 243.0 0.0 2.1e-71 240.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX93822.1 - 3.1e-22 78.2 1.5 2.4e-21 75.4 0.2 2.9 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.7 KFX93822.1 - 7.5e-18 64.5 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain M60-like PF13402.1 KFX93822.1 - 0.011 14.6 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase M60-like family Cation_efflux PF01545.16 KFX93823.1 - 1.7e-75 253.7 7.0 1.7e-75 253.7 4.8 2.3 2 1 0 2 2 2 1 Cation efflux family DUF202 PF02656.10 KFX93823.1 - 2.3e-15 56.5 0.3 2.3e-15 56.5 0.2 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF202) Sugar_tr PF00083.19 KFX93824.1 - 3.5e-122 408.2 27.1 3.9e-122 408.0 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93824.1 - 6.8e-25 87.5 57.4 1.8e-23 82.8 18.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 KFX93824.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93824.1 - 0.16 12.6 0.1 0.31 11.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4131 PF13567.1 KFX93824.1 - 2.5 7.5 14.9 4.5 6.6 0.3 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) GIT_SHD PF08518.6 KFX93826.1 - 6.5e-23 79.7 5.5 4.4e-14 51.5 0.3 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT HCMV_UL139 PF12507.3 KFX93826.1 - 0.057 13.5 2.9 0.96 9.6 0.8 2.9 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein HALZ PF02183.13 KFX93826.1 - 0.18 11.5 13.0 0.51 10.0 1.0 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 KFX93826.1 - 1.6 9.0 11.5 0.48 10.7 0.2 4.6 2 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 KFX93826.1 - 2.7 7.8 45.8 2.1 8.1 13.2 4.3 2 1 2 4 4 4 0 Tropomyosin like Ssu72 PF04722.8 KFX93827.1 - 3.2e-85 284.3 0.0 3.7e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.23 KFX93828.1 - 4.6e-09 35.5 0.0 7.8e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX93828.1 - 1.2e-08 34.3 0.1 2.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX93828.1 - 8.3e-06 25.2 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NMU PF02070.10 KFX93828.1 - 0.04 13.4 0.8 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 Neuromedin U Peptidase_M22 PF00814.20 KFX93829.1 - 8.3e-75 251.7 0.0 9.4e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 KFX93829.1 - 0.11 12.0 0.0 0.62 9.5 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein AMPKBI PF04739.10 KFX93830.1 - 1.7e-29 101.6 0.7 1.7e-29 101.6 0.5 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Pribosyl_synth PF14572.1 KFX93830.1 - 0.18 11.5 0.8 0.38 10.4 0.5 1.5 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain MCPVI PF02993.9 KFX93830.1 - 9.2 6.3 14.7 6.6 6.8 0.3 2.6 2 0 0 2 2 2 0 Minor capsid protein VI EpsG PF14897.1 KFX93831.1 - 0.0049 15.8 0.1 0.0059 15.5 0.1 1.0 1 0 0 1 1 1 1 EpsG family Myc_target_1 PF15179.1 KFX93831.1 - 0.038 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 Pkinase PF00069.20 KFX93832.1 - 1.7e-60 204.3 0.0 2.2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93832.1 - 8.3e-26 90.6 0.0 1.4e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX93832.1 - 0.049 12.5 0.0 0.15 11.0 0.0 1.7 2 1 0 2 2 2 0 Kinase-like Peptidase_C78 PF07910.8 KFX93834.1 - 4.8e-67 225.2 0.0 7.5e-67 224.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.11 KFX93834.1 - 1.4e-51 174.5 0.0 2e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Ham1 family zf-Di19 PF05605.7 KFX93834.1 - 0.018 15.1 0.2 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AAA_18 PF13238.1 KFX93835.1 - 1.3e-27 96.6 0.6 2e-27 96.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX93835.1 - 3e-16 60.3 0.4 4.9e-16 59.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX93835.1 - 6.6e-06 26.3 0.1 0.00046 20.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFX93835.1 - 7.8e-05 22.5 0.1 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KFX93835.1 - 0.00013 21.8 0.8 0.0042 16.9 0.6 2.4 1 1 0 1 1 1 1 Adenylate kinase AAA_28 PF13521.1 KFX93835.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KFX93835.1 - 0.0003 20.5 0.0 0.00057 19.6 0.0 1.6 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 KFX93835.1 - 0.00069 19.0 0.5 0.49 9.7 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 KFX93835.1 - 0.00073 18.8 0.1 0.0023 17.1 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 KFX93835.1 - 0.0017 17.8 0.5 0.0031 16.9 0.1 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family SKI PF01202.17 KFX93835.1 - 0.002 18.0 1.2 0.014 15.2 0.8 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 KFX93835.1 - 0.0025 17.9 0.0 0.0055 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFX93835.1 - 0.0068 16.3 0.1 0.018 14.9 0.0 1.8 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFX93835.1 - 0.0076 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 KFX93835.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KFX93835.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFX93835.1 - 0.03 13.9 0.1 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFX93835.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX93835.1 - 0.045 13.4 0.2 0.082 12.6 0.2 1.4 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 KFX93835.1 - 0.047 13.3 0.1 0.086 12.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFX93835.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.17 KFX93835.1 - 0.065 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Dna2 PF08696.6 KFX93835.1 - 0.072 12.3 0.6 0.16 11.2 0.4 1.6 1 0 0 1 1 1 0 DNA replication factor Dna2 AAA_5 PF07728.9 KFX93835.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 KFX93835.1 - 0.096 12.2 0.8 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cytidylate_kin2 PF13189.1 KFX93835.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase-like family ArgK PF03308.11 KFX93835.1 - 0.1 11.3 0.8 0.14 10.9 0.1 1.6 2 0 0 2 2 2 0 ArgK protein Viral_helicase1 PF01443.13 KFX93835.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 KFX93835.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KFX93835.1 - 0.16 10.8 1.9 0.15 10.9 0.4 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Myosin_head PF00063.16 KFX93836.1 - 5e-243 808.1 0.0 5e-243 808.1 0.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KFX93836.1 - 1.5e-34 118.0 3.6 4.3e-34 116.5 2.5 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KFX93836.1 - 3.2e-14 51.1 28.3 0.00015 21.1 0.8 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KFX93836.1 - 0.0011 19.1 0.1 0.0055 16.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain Myosin_N PF02736.14 KFX93836.1 - 0.0096 15.5 0.2 0.025 14.2 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 KFX93836.1 - 0.013 15.4 0.0 0.065 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFX93836.1 - 0.018 14.7 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain zf-C4H2 PF10146.4 KFX93836.1 - 0.078 12.9 6.5 0.23 11.4 4.5 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein Reo_sigmaC PF04582.7 KFX93836.1 - 0.6 9.2 3.3 1.2 8.1 1.2 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KFX93836.1 - 2.7 7.9 8.8 0.19 11.6 0.3 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.22 KFX93836.1 - 4.6 7.5 8.9 2.8 8.2 0.0 4.2 4 1 0 4 4 3 0 ABC transporter ArgJ PF01960.13 KFX93837.1 - 7.6e-148 492.0 0.4 8.6e-148 491.8 0.3 1.0 1 0 0 1 1 1 1 ArgJ family A_deamin PF02137.13 KFX93837.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain ORC2 PF04084.9 KFX93838.1 - 4.8e-104 347.7 0.0 5.8e-104 347.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 KFX93838.1 - 0.11 12.2 19.2 0.62 9.9 2.6 3.2 2 0 0 2 2 2 0 AT hook motif zf-PARP PF00645.13 KFX93839.1 - 7.8e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF410 PF04190.8 KFX93840.1 - 1.6e-51 175.3 0.0 1.9e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Response_reg PF00072.19 KFX93846.1 - 2e-20 72.8 0.0 5.3e-14 52.1 0.0 2.8 2 1 1 3 3 3 2 Response regulator receiver domain PQ-loop PF04193.9 KFX93847.1 - 1.3e-19 69.4 7.4 5.6e-12 45.0 0.3 3.2 2 1 1 3 3 3 2 PQ loop repeat UL2 PF08196.6 KFX93847.1 - 0.076 12.7 0.8 0.2 11.4 0.5 1.7 1 0 0 1 1 1 0 UL2 protein Pep_deformylase PF01327.16 KFX93847.1 - 0.11 11.8 0.1 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase ABC2_membrane_5 PF13346.1 KFX93847.1 - 2.2 7.5 15.0 0.45 9.7 6.5 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein SNase PF00565.12 KFX93848.1 - 4.2e-67 223.2 0.9 2e-23 82.6 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KFX93848.1 - 1.7e-23 82.7 0.0 6.6e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 KFX93848.1 - 7.8e-05 21.9 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF1939 PF09154.5 KFX93850.1 - 0.042 13.7 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) PHD PF00628.24 KFX93851.1 - 1.8e-09 37.1 2.2 1.8e-09 37.1 1.5 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 KFX93851.1 - 0.002 17.4 2.0 0.0035 16.6 1.4 1.4 1 0 0 1 1 1 1 PHD-finger UIM PF02809.15 KFX93851.1 - 0.0055 16.1 0.2 0.019 14.4 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD PF00628.24 KFX93854.1 - 2.6e-07 30.2 8.8 4.9e-07 29.3 6.1 1.5 1 0 0 1 1 1 1 PHD-finger Glycos_transf_4 PF00953.16 KFX93855.1 - 6e-31 107.3 7.8 6e-31 107.3 5.4 1.8 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 KFX93856.1 - 2.1e-21 74.9 3.7 7.6e-06 25.6 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Metallophos PF00149.23 KFX93858.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 KFX93859.1 - 1.3e-16 59.7 11.1 5.7e-06 25.8 3.7 4.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX93859.1 - 7.9e-11 41.5 13.3 9.4e-08 31.6 4.1 4.5 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 KFX93859.1 - 7.4e-10 37.4 11.7 0.59 10.3 0.6 6.7 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KFX93859.1 - 3e-05 23.4 8.8 13 6.4 0.1 6.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KFX93859.1 - 0.0033 17.3 11.2 28 5.1 0.0 5.9 3 1 2 5 5 5 1 Leucine Rich repeat Rdx PF10262.4 KFX93860.1 - 6.9e-28 96.5 0.0 1.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 KFX93860.1 - 1.2e-23 82.6 0.0 1.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 GGL domain RPN7 PF10602.4 KFX93867.1 - 2e-44 151.1 0.8 3.6e-44 150.2 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFX93867.1 - 7.5e-14 51.9 1.0 2.8e-13 50.1 0.0 2.4 3 0 0 3 3 3 1 PCI domain DUF3227 PF11537.3 KFX93867.1 - 0.0087 16.1 0.0 0.06 13.4 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3227) TPR_2 PF07719.12 KFX93867.1 - 0.011 15.6 5.0 1.3 9.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX93867.1 - 0.15 11.7 7.9 3 7.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX93867.1 - 0.15 11.8 3.7 5.4 7.0 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3431 PF11913.3 KFX93868.1 - 3.5e-85 284.9 1.0 4.8e-85 284.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phasin PF05597.6 KFX93868.1 - 0.028 14.1 0.3 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Mhr1 PF12829.2 KFX93869.1 - 3.6e-28 97.2 0.1 6.7e-28 96.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF1205 PF06722.7 KFX93869.1 - 0.0065 16.6 0.2 0.027 14.7 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1205) AAA_2 PF07724.9 KFX93870.1 - 2.4e-47 160.9 0.0 3.6e-46 157.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFX93870.1 - 2.7e-26 92.3 0.1 2.6e-14 53.5 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KFX93870.1 - 7.4e-25 86.6 0.2 2.6e-24 84.9 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KFX93870.1 - 8.5e-16 58.4 12.5 1e-05 25.5 0.0 6.5 3 2 2 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 KFX93870.1 - 6.4e-15 55.0 0.0 2.3e-09 37.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX93870.1 - 5.7e-13 49.1 0.0 0.00012 22.2 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 KFX93870.1 - 2e-08 35.0 2.5 0.014 16.1 0.7 3.7 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KFX93870.1 - 8.5e-08 31.8 0.0 4.5e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KFX93870.1 - 4.1e-07 30.3 0.5 0.013 15.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KFX93870.1 - 5e-07 29.3 0.0 0.03 14.0 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 KFX93870.1 - 1.1e-06 28.2 0.0 0.029 13.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFX93870.1 - 4.3e-06 26.0 0.0 0.18 10.9 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Clp_N PF02861.15 KFX93870.1 - 2.7e-05 24.0 2.9 0.004 17.0 0.1 3.8 3 0 0 3 3 3 1 Clp amino terminal domain AAA_28 PF13521.1 KFX93870.1 - 3.9e-05 23.6 0.0 0.27 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX93870.1 - 5.1e-05 23.1 0.0 0.32 10.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFX93870.1 - 6.3e-05 23.1 0.0 0.44 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 KFX93870.1 - 0.00011 21.1 1.4 0.017 13.9 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 KFX93870.1 - 0.00015 21.3 0.0 0.76 9.3 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFX93870.1 - 0.00028 20.5 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX93870.1 - 0.00032 20.1 0.5 1.5 8.1 0.0 3.5 3 1 1 4 4 4 2 AAA domain ResIII PF04851.10 KFX93870.1 - 0.00041 20.2 0.0 0.36 10.6 0.0 3.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KFX93870.1 - 0.00057 19.6 14.3 0.01 15.5 0.2 5.7 3 3 0 4 4 3 1 Archaeal ATPase MobB PF03205.9 KFX93870.1 - 0.00068 19.3 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KFX93870.1 - 0.0011 18.1 0.0 0.53 9.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX93870.1 - 0.0015 18.0 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX93870.1 - 0.0028 17.9 3.0 0.85 9.9 0.0 3.7 4 0 0 4 4 3 1 ABC transporter NACHT PF05729.7 KFX93870.1 - 0.0058 16.2 0.0 0.62 9.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.6 KFX93870.1 - 0.01 15.7 0.0 0.082 12.7 0.0 2.4 3 0 0 3 3 3 0 Torsin AAA_10 PF12846.2 KFX93870.1 - 0.016 14.6 7.7 0.59 9.5 0.1 5.1 4 2 1 6 6 6 0 AAA-like domain AAA_21 PF13304.1 KFX93870.1 - 0.018 14.9 0.2 1.8 8.4 0.0 3.1 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.10 KFX93870.1 - 0.02 14.5 0.0 0.4 10.3 0.0 2.7 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 KFX93870.1 - 0.054 13.1 0.0 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KFX93870.1 - 0.087 12.3 0.0 6.7 6.1 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YycI PF09648.5 KFX93870.1 - 1.9 7.8 8.4 0.25 10.7 1.8 2.2 2 0 0 2 2 2 0 YycH protein Methyltransf_11 PF08241.7 KFX93871.1 - 1.3e-09 38.3 0.0 3.8e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX93871.1 - 3.6e-08 33.2 0.0 5.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX93871.1 - 6.9e-08 32.8 0.0 1.6e-07 31.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX93871.1 - 2.6e-07 30.9 0.0 1.5e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX93871.1 - 8.4e-06 25.4 0.0 1.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX93871.1 - 6.6e-05 22.1 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFX93871.1 - 0.00049 20.6 0.1 0.0013 19.2 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 KFX93871.1 - 0.17 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Biotin_lipoyl PF00364.17 KFX93872.1 - 8.4e-20 70.2 0.8 2.2e-19 68.8 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KFX93872.1 - 5.6e-05 22.7 0.7 0.00024 20.6 0.0 2.5 3 0 0 3 3 3 1 Biotin-lipoyl like E3_binding PF02817.12 KFX93872.1 - 0.008 15.7 0.0 0.03 13.9 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain HTH_Tnp_ISL3 PF13542.1 KFX93872.1 - 0.023 13.8 0.7 0.043 13.0 0.5 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 SNARE PF05739.14 KFX93874.1 - 2.7e-08 33.3 1.4 7.2e-08 32.0 1.0 1.7 1 0 0 1 1 1 1 SNARE domain BCIP PF13862.1 KFX93874.1 - 0.033 13.6 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein CNH PF00780.17 KFX93896.1 - 1.6e-82 277.0 0.0 2.5e-82 276.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KFX93896.1 - 1.1e-44 151.6 0.3 3.1e-44 150.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 KFX93896.1 - 2.3e-36 125.3 0.0 3.7e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KFX93896.1 - 1.4e-13 50.3 0.0 6.3e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mito_carr PF00153.22 KFX93898.1 - 3.8e-05 23.3 0.0 4.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Redoxin PF08534.5 KFX93906.1 - 1.5e-26 92.7 0.0 1.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFX93906.1 - 9.8e-07 28.4 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Rhodanese PF00581.15 KFX93908.1 - 6.4e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain SBF PF01758.11 KFX93909.1 - 1.3e-46 158.3 15.9 1.3e-46 158.3 11.0 2.4 2 1 1 3 3 3 2 Sodium Bile acid symporter family MFS_1 PF07690.11 KFX93910.1 - 3.1e-29 101.8 65.8 9.8e-27 93.5 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX93910.1 - 0.014 15.1 3.8 0.014 15.1 2.6 4.1 3 1 1 4 4 4 0 MFS_1 like family Sugar_tr PF00083.19 KFX93910.1 - 0.035 12.7 37.7 0.18 10.3 11.0 2.7 2 1 0 2 2 2 0 Sugar (and other) transporter FMN_dh PF01070.13 KFX93925.1 - 1.2e-115 386.1 0.0 1.5e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFX93925.1 - 1.9e-06 27.0 0.0 3.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KFX93925.1 - 2e-05 23.9 0.1 8.6e-05 21.8 0.0 1.8 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 KFX93925.1 - 8.7e-05 21.5 0.8 0.00084 18.3 0.2 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFX93925.1 - 0.00012 21.2 0.0 0.046 12.7 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KFX93925.1 - 0.032 13.1 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KFX93925.1 - 0.09 12.0 0.1 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein Dus PF01207.12 KFX93925.1 - 0.13 11.0 0.0 3.5 6.3 0.0 2.5 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) Methyltransf_16 PF10294.4 KFX93929.1 - 3.3e-40 137.3 0.0 4.9e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX93929.1 - 8.7e-07 29.5 0.0 2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX93929.1 - 1.3e-05 24.6 0.0 2.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFX93929.1 - 1.8e-05 24.0 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFX93929.1 - 0.00082 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX93929.1 - 0.0014 18.9 0.0 0.0068 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX93929.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFX93929.1 - 0.0032 16.5 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 KFX93929.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KFX93929.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FAA_hydrolase PF01557.13 KFX93930.1 - 1.5e-46 158.5 0.0 2.1e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KFX93930.1 - 9e-27 93.1 0.0 4.7e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal DUF3516 PF12029.3 KFX93930.1 - 0.22 10.3 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) p450 PF00067.17 KFX93931.1 - 3.5e-58 197.2 0.0 4.3e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KFX93932.1 - 2e-16 59.6 0.0 5.2e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93932.1 - 6.4e-09 35.5 10.6 1.2e-08 34.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3431 PF11913.3 KFX93932.1 - 0.044 13.2 0.6 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) Sugar_tr PF00083.19 KFX93934.1 - 5.4e-73 246.0 24.3 6.3e-73 245.8 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93934.1 - 5.5e-32 110.8 33.8 1.1e-26 93.4 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_6 PF02949.15 KFX93934.1 - 0.22 10.3 3.2 0.31 9.8 0.2 2.4 2 1 1 3 3 3 0 7tm Odorant receptor OppC_N PF12911.2 KFX93937.1 - 0.0016 17.8 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C TBPIP PF07106.8 KFX93937.1 - 0.0026 17.3 4.3 0.0089 15.5 0.2 2.2 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 KFX93937.1 - 0.0073 16.5 0.2 15 5.9 0.0 3.5 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Cation_ATPase_C PF00689.16 KFX93937.1 - 0.054 13.0 0.1 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Fmp27_WPPW PF10359.4 KFX93937.1 - 0.066 11.6 5.1 5.4 5.3 3.0 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Herpes_U30 PF04523.8 KFX93937.1 - 0.07 10.5 3.9 0.46 7.8 0.9 2.1 2 0 0 2 2 2 0 Herpes virus tegument protein U30 Rifin_STEVOR PF02009.11 KFX93937.1 - 0.1 12.2 1.4 0.18 11.4 0.9 1.4 1 0 0 1 1 1 0 Rifin/stevor family T2SF PF00482.18 KFX93937.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Baculo_PEP_C PF04513.7 KFX93937.1 - 0.11 12.2 0.7 2.8 7.7 0.0 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.1 KFX93937.1 - 0.16 12.3 4.7 0.97 9.8 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) GP41 PF00517.12 KFX93937.1 - 0.2 11.2 4.9 0.053 13.0 0.3 2.2 2 1 1 3 3 3 0 Retroviral envelope protein EMP24_GP25L PF01105.19 KFX93937.1 - 0.37 10.4 6.1 0.36 10.5 0.5 2.7 2 2 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Allexi_40kDa PF05549.6 KFX93937.1 - 0.38 10.0 5.7 1.1 8.4 0.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF948 PF06103.6 KFX93937.1 - 5 7.0 8.5 12 5.8 0.0 3.9 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) adh_short_C2 PF13561.1 KFX93938.1 - 3.1e-26 92.6 0.2 3.8e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX93938.1 - 1.9e-25 89.6 0.2 3.4e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX93938.1 - 1.2e-08 34.8 0.3 4.3e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX93938.1 - 0.0015 18.0 0.1 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RabGAP-TBC PF00566.13 KFX93939.1 - 2e-50 171.2 0.1 3.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PAP2 PF01569.16 KFX93941.1 - 1.4e-16 60.3 4.0 2.5e-16 59.5 2.3 1.7 1 1 0 1 1 1 1 PAP2 superfamily HLH PF00010.21 KFX93943.1 - 4.3e-09 35.9 0.0 9e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Vasculin PF15337.1 KFX93943.1 - 0.066 13.6 0.2 0.066 13.6 0.1 1.8 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 NST1 PF13945.1 KFX93943.1 - 0.97 9.4 6.2 1.7 8.6 4.3 1.5 1 1 0 1 1 1 0 Salt tolerance down-regulator AT_hook PF02178.14 KFX93949.1 - 0.00031 20.0 11.8 0.42 10.4 5.5 3.2 2 0 0 2 2 2 2 AT hook motif SET PF00856.23 KFX93952.1 - 4.8e-23 82.2 0.3 4.8e-23 82.2 0.2 2.9 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KFX93952.1 - 3.3e-20 71.8 9.0 9.5e-20 70.3 6.2 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 KFX93952.1 - 0.15 11.6 0.5 0.64 9.5 0.1 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain WW PF00397.21 KFX93952.1 - 2.6 7.9 5.7 13 5.7 4.0 2.1 1 1 0 1 1 1 0 WW domain CRAL_TRIO PF00650.15 KFX93955.1 - 6.5e-37 126.4 0.0 9.6e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX93955.1 - 6.6e-08 32.5 0.1 1.8e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFX93955.1 - 6.5e-06 26.1 0.0 2.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Prefoldin PF02996.12 KFX93956.1 - 2.7e-31 107.6 0.1 5.5e-31 106.6 0.0 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 KFX93956.1 - 0.007 16.1 0.5 0.099 12.4 0.0 2.4 2 1 1 3 3 3 1 Prefoldin subunit MAD PF05557.8 KFX93956.1 - 0.038 12.0 1.6 0.092 10.8 0.1 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein SlyX PF04102.7 KFX93956.1 - 0.072 13.4 1.0 10 6.5 0.1 2.7 3 0 0 3 3 3 0 SlyX DUF4201 PF13870.1 KFX93956.1 - 0.14 11.6 1.8 2 7.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3112 PF11309.3 KFX93957.1 - 1.2e-51 174.7 15.1 4.2e-49 166.4 2.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Zn_clus PF00172.13 KFX93958.1 - 9.5e-07 28.6 9.6 1.8e-06 27.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 KFX93968.1 - 3.2e-83 278.9 0.5 3.2e-83 278.9 0.3 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KFX93968.1 - 1e-18 67.0 0.2 3.6e-18 65.2 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KFX93968.1 - 3.2e-17 62.1 0.1 1.9e-16 59.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 KFX93968.1 - 2.5e-16 59.6 2.0 2.5e-16 59.6 1.4 3.1 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KFX93968.1 - 2e-14 53.1 12.4 2e-14 53.1 8.6 3.3 4 0 0 4 4 4 1 HSA QLQ PF08880.6 KFX93968.1 - 9.9e-12 44.0 0.1 2.6e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 QLQ SUR7 PF06687.7 KFX93968.1 - 5.2 6.5 6.3 9 5.7 4.4 1.3 1 0 0 1 1 1 0 SUR7/PalI family TPR_11 PF13414.1 KFX93969.1 - 7.6e-31 105.5 21.8 9.1e-10 38.0 2.7 9.6 8 2 2 10 10 10 5 TPR repeat TPR_2 PF07719.12 KFX93969.1 - 9e-31 103.2 18.5 9.4e-05 22.0 0.0 11.3 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.23 KFX93969.1 - 1.8e-29 100.0 21.3 3.5e-06 26.3 0.0 10.9 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFX93969.1 - 4.1e-21 73.1 19.1 8.8e-05 22.0 0.1 10.5 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93969.1 - 1.8e-20 73.0 22.2 9.8e-05 22.6 0.0 10.5 8 3 2 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 KFX93969.1 - 4.8e-18 64.8 26.0 1.8e-05 24.5 2.9 9.4 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX93969.1 - 6.5e-15 54.2 35.9 0.002 18.5 0.0 12.6 10 3 3 13 13 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX93969.1 - 7.3e-14 50.3 24.1 0.00025 20.5 0.1 12.1 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX93969.1 - 1.2e-11 43.7 6.7 5.3 7.4 0.0 11.0 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93969.1 - 1.4e-11 44.7 38.3 0.0011 19.5 2.2 11.3 10 2 2 12 12 11 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFX93969.1 - 7.4e-07 28.9 9.8 0.15 12.0 0.1 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFX93969.1 - 0.00032 20.9 27.4 3.1 8.4 0.0 10.8 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_3 PF07720.7 KFX93969.1 - 0.26 11.1 7.2 5.8 6.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.23 KFX93971.1 - 1.9e-06 28.3 0.0 8.3e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 SET domain F-box-like PF12937.2 KFX93972.1 - 2.8e-08 33.3 0.3 1.4e-07 31.1 0.2 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX93972.1 - 0.0014 18.2 0.6 0.0054 16.3 0.2 2.3 1 1 1 2 2 2 1 F-box domain COesterase PF00135.23 KFX93973.1 - 9.3e-89 298.5 0.0 1.2e-88 298.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX93973.1 - 8.4e-07 28.7 0.1 2.4e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX93973.1 - 0.034 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX93973.1 - 0.11 11.1 0.2 0.27 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Aconitase PF00330.15 KFX93974.1 - 8.1e-65 219.0 0.0 1.7e-40 138.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFX93974.1 - 4.8e-23 81.7 0.0 9e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain GST_C_4 PF14834.1 KFX93974.1 - 0.13 12.2 0.0 26 4.7 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Erf4 PF10256.4 KFX93976.1 - 2.1e-20 72.7 0.0 2.5e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family polyprenyl_synt PF00348.12 KFX93988.1 - 1.9e-45 154.7 0.0 3.5e-45 153.8 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase 2OG-FeII_Oxy PF03171.15 KFX93999.1 - 4.9e-16 58.8 0.0 7.6e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-met2 PF12907.2 KFX94000.1 - 1.8e-15 56.5 3.7 2.5e-15 56.1 2.5 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KFX94000.1 - 6.1e-05 23.6 9.8 9.5e-05 23.0 6.8 1.3 1 0 0 1 1 1 1 4F5 protein family LUC7 PF03194.10 KFX94000.1 - 0.068 12.6 0.6 0.075 12.5 0.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus SR-25 PF10500.4 KFX94000.1 - 0.087 12.2 2.0 0.098 12.1 1.4 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_primase_lrg PF04104.9 KFX94004.1 - 2e-08 33.8 0.0 3.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF2264 PF10022.4 KFX94005.1 - 1.6e-125 418.5 0.0 2e-125 418.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Sugar_tr PF00083.19 KFX94006.1 - 2.2e-113 379.2 21.1 2.6e-113 379.0 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94006.1 - 1.1e-21 77.0 27.5 1.1e-21 77.0 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.7 KFX94007.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.18 KFX94016.1 - 2.9e-10 40.2 0.0 1.6e-09 37.8 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KFX94016.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase zf-BED PF02892.10 KFX94017.1 - 0.038 13.7 0.9 0.18 11.6 0.2 2.1 2 0 0 2 2 2 0 BED zinc finger TFIIA_gamma_C PF02751.9 KFX94019.1 - 2.7e-08 33.5 0.9 4.4e-08 32.8 0.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KFX94019.1 - 6.5e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Pro_isomerase PF00160.16 KFX94020.1 - 2.7e-41 141.3 0.0 4.6e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD XAP5 PF04921.9 KFX94020.1 - 1.4 8.4 5.1 0.28 10.7 0.5 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF4291 PF14124.1 KFX94021.1 - 7.7e-63 211.3 0.5 1.1e-62 210.9 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) K_trans PF02705.11 KFX94022.1 - 4.6e-182 606.1 27.1 5.4e-182 605.8 18.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter zf-RING_2 PF13639.1 KFX94023.1 - 6.9e-16 57.8 5.5 1.1e-15 57.1 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFX94023.1 - 7.3e-10 38.4 4.8 1.2e-09 37.7 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFX94023.1 - 1.3e-08 34.8 2.2 2.4e-08 33.9 1.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFX94023.1 - 2.3e-08 33.5 2.9 3.5e-08 32.9 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX94023.1 - 2.3e-08 33.5 6.5 3.8e-08 32.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX94023.1 - 1.1e-07 31.6 6.7 1.9e-07 31.0 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX94023.1 - 0.00011 22.0 1.2 0.00021 21.0 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.4 KFX94023.1 - 0.0019 18.3 1.0 0.15 12.2 0.1 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.3 KFX94023.1 - 0.0059 16.5 6.1 0.14 12.1 4.2 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 KFX94023.1 - 0.0063 16.0 3.4 0.011 15.3 2.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KFX94023.1 - 0.0095 15.6 1.4 0.0095 15.6 1.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.1 KFX94023.1 - 0.013 15.2 4.0 0.19 11.4 2.7 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RINGv PF12906.2 KFX94023.1 - 0.03 14.3 5.6 0.068 13.2 3.9 1.7 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 KFX94023.1 - 0.031 13.7 4.2 0.058 12.8 2.9 1.5 1 0 0 1 1 1 0 P-11 zinc finger PHD PF00628.24 KFX94023.1 - 0.044 13.4 3.0 0.08 12.6 2.1 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.1 KFX94023.1 - 0.048 13.2 2.9 0.12 11.9 2.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KFX94023.1 - 0.052 13.4 4.4 0.13 12.1 3.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING GAGA PF09237.6 KFX94023.1 - 0.059 12.9 1.6 0.48 10.0 0.1 2.4 2 0 0 2 2 2 0 GAGA factor U-box PF04564.10 KFX94023.1 - 0.073 13.0 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 U-box domain zf-Nse PF11789.3 KFX94023.1 - 0.13 11.7 2.5 0.29 10.6 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_1 PF00130.17 KFX94023.1 - 0.16 11.7 3.1 0.64 9.7 0.5 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rad50_zn_hook PF04423.9 KFX94023.1 - 0.19 11.2 0.2 0.19 11.2 0.2 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 KFX94023.1 - 0.28 10.9 1.9 0.55 10.0 1.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein E1-E2_ATPase PF00122.15 KFX94024.1 - 2.6e-49 167.3 3.5 2.6e-49 167.3 2.4 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX94024.1 - 9.9e-40 136.0 4.5 9.9e-40 136.0 3.1 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX94024.1 - 1.3e-33 117.2 0.0 5.3e-32 111.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX94024.1 - 3.7e-21 74.8 0.0 8e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFX94024.1 - 9.7e-14 51.9 0.0 4.7e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX94024.1 - 8.5e-10 37.9 0.0 1.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFX94024.1 - 0.00053 19.6 0.3 0.0016 18.1 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 KFX94024.1 - 2.6 6.6 11.9 0.93 8.1 1.8 3.0 3 0 0 3 3 3 0 Predicted permease YjgP/YjgQ family DUF21 PF01595.15 KFX94025.1 - 3.1e-29 101.5 2.0 3.7e-29 101.3 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 KFX94025.1 - 2e-09 37.0 0.3 4.4e-08 32.7 0.1 2.8 3 0 0 3 3 3 1 CBS domain DS PF01916.12 KFX94026.1 - 1.2e-146 487.5 0.0 1.4e-146 487.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KFX94026.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-bind_6 PF13921.1 KFX94027.1 - 0.29 11.2 5.0 3.5 7.7 0.2 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain P21-Arc PF04062.9 KFX94028.1 - 5.3e-80 267.2 0.0 6e-80 267.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.8 KFX94029.1 - 1.9e-80 270.2 0.0 2.4e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family WD40 PF00400.27 KFX94045.1 - 2.6e-12 46.1 5.7 0.058 13.2 0.0 6.6 6 2 0 6 6 6 4 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KFX94046.1 - 2.8e-11 42.6 1.0 4e-10 38.8 0.7 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain GST_N_2 PF13409.1 KFX94047.1 - 1.5e-20 72.9 0.0 7.3e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX94047.1 - 2.5e-12 46.5 0.0 7.6e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX94047.1 - 3.1e-06 27.3 0.0 0.021 15.0 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX94047.1 - 0.0014 19.0 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pox_E2-like PF04497.7 KFX94047.1 - 0.13 10.2 0.1 0.23 9.4 0.1 1.3 1 0 0 1 1 1 0 Poxviridae protein MFS_1 PF07690.11 KFX94048.1 - 1.8e-26 92.6 28.7 1.8e-26 92.6 19.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX94048.1 - 0.25 11.1 10.2 1.1 9.1 0.2 2.9 2 0 0 2 2 2 0 MFS_1 like family ABC_tran PF00005.22 KFX94049.1 - 3.8e-28 98.4 0.0 9.9e-15 55.0 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFX94049.1 - 4.2e-14 53.2 0.7 3.6e-07 30.4 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFX94049.1 - 7.8e-07 29.6 2.5 0.056 13.7 1.8 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFX94049.1 - 6.5e-05 22.7 0.0 0.0045 16.8 0.0 2.7 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KFX94049.1 - 7.5e-05 22.1 0.0 0.045 13.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX94049.1 - 0.00011 22.9 0.0 0.28 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KFX94049.1 - 0.00067 18.8 0.0 0.16 10.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KFX94049.1 - 0.00086 19.2 0.0 0.99 9.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 KFX94049.1 - 0.0013 19.2 0.0 0.49 10.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 KFX94049.1 - 0.0015 18.5 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX94049.1 - 0.0057 16.1 0.0 0.45 9.9 0.0 2.5 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KFX94049.1 - 0.017 15.2 0.0 3 7.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFX94049.1 - 0.025 14.8 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KFX94049.1 - 0.027 13.7 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.1 KFX94049.1 - 0.046 13.7 0.2 8.7 6.2 0.1 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 KFX94049.1 - 0.052 13.4 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFX94049.1 - 0.054 13.1 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 KFX94049.1 - 0.055 13.1 0.0 8.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFX94049.1 - 0.075 12.5 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 KFX94049.1 - 0.08 11.6 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_25 PF13481.1 KFX94049.1 - 0.09 12.1 0.0 4.8 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 KFX94049.1 - 0.11 11.7 0.0 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KFX94049.1 - 0.12 11.8 0.1 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KFX94049.1 - 0.15 11.6 0.0 25 4.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 KFX94049.1 - 0.17 11.3 0.0 17 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KFX94049.1 - 0.17 11.8 0.1 29 4.6 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase Pantoate_ligase PF02569.10 KFX94053.1 - 3.1e-82 275.5 0.0 6.1e-82 274.5 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Methyltransf_2 PF00891.13 KFX94059.1 - 4.3e-23 81.7 0.0 6.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KFX94059.1 - 0.00025 20.8 0.3 0.00093 18.9 0.2 2.0 1 0 0 1 1 1 1 Dimerisation domain HTH_24 PF13412.1 KFX94059.1 - 0.0016 17.8 0.0 0.0045 16.3 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 KFX94059.1 - 0.0022 17.5 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.17 KFX94059.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 KFX94059.1 - 0.12 12.2 0.4 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3164 PF11363.3 KFX94059.1 - 0.19 11.1 0.1 1.6 8.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3164) HTH_IclR PF09339.5 KFX94059.1 - 0.22 11.1 1.1 0.76 9.4 0.0 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain APH PF01636.18 KFX94060.1 - 1.8e-05 24.6 0.1 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX94060.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase FA_desaturase PF00487.19 KFX94083.1 - 5.6e-27 94.8 22.3 1.7e-26 93.2 15.5 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KFX94083.1 - 3.5e-06 27.0 0.0 6.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) SMC_N PF02463.14 KFX94084.1 - 3.8e-67 225.7 0.0 4.3e-66 222.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX94084.1 - 4.7e-28 97.5 0.5 2.2e-27 95.3 0.0 2.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFX94084.1 - 2.8e-13 50.4 0.0 3.3e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFX94084.1 - 5.4e-13 49.7 25.2 5.4e-13 49.7 17.5 6.0 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 KFX94084.1 - 0.0009 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KFX94084.1 - 0.022 13.8 23.1 0.25 10.3 0.0 3.7 3 2 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.1 KFX94084.1 - 0.15 10.4 0.0 0.15 10.4 0.0 5.7 3 2 1 5 5 5 0 AAA domain ABC_tran PF00005.22 KFX94084.1 - 0.36 11.1 0.0 0.36 11.1 0.0 5.7 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 KFX94084.1 - 2.8 7.0 21.3 0.46 9.5 0.1 4.8 2 2 0 4 4 4 0 Reovirus sigma C capsid protein RIO1 PF01163.17 KFX94085.1 - 1.8e-67 226.3 1.1 1.9e-67 226.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFX94085.1 - 0.00019 20.5 0.2 0.0016 17.5 0.1 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX94085.1 - 0.00089 19.0 1.5 0.61 9.7 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Prismane PF03063.15 KFX94085.1 - 0.054 11.8 0.0 0.091 11.1 0.0 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family SNARE PF05739.14 KFX94086.1 - 4.4e-19 67.9 1.9 4.4e-19 67.9 1.3 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFX94086.1 - 2.7e-13 49.9 0.4 2.7e-13 49.9 0.3 2.5 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KFX94086.1 - 0.0024 17.4 6.6 0.0064 16.0 0.6 2.5 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.1 KFX94086.1 - 0.25 11.7 0.1 0.25 11.7 0.0 2.7 3 1 0 3 3 3 0 DNA repair REX1-B EF-hand_1 PF00036.27 KFX94087.1 - 2.1e-40 132.9 12.8 1.8e-09 36.1 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFX94087.1 - 3.2e-36 123.2 6.4 4.7e-20 71.5 0.8 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KFX94087.1 - 7.4e-34 115.1 12.7 1.1e-15 56.9 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFX94087.1 - 1.1e-29 99.5 8.4 2.1e-09 36.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFX94087.1 - 3.6e-25 86.1 9.7 2.3e-06 26.6 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFX94087.1 - 2e-15 56.4 0.2 4.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFX94087.1 - 7.6e-09 35.6 0.3 0.0028 17.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFX94087.1 - 3.9e-08 32.9 2.8 0.0034 17.1 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KFX94087.1 - 1.3e-07 31.1 0.1 0.038 13.6 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFX94087.1 - 3.7e-06 26.8 2.1 2e-05 24.4 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KFX94087.1 - 0.0003 20.5 0.4 0.54 9.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KFX94087.1 - 0.0011 18.5 0.1 0.12 11.9 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 KFX94087.1 - 0.0056 16.6 0.9 1.6 8.7 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 Tenui_NCP PF04876.7 KFX94087.1 - 0.0064 16.0 0.1 0.26 10.8 0.0 2.4 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 KFX94087.1 - 0.0082 16.4 2.6 0.69 10.2 0.1 2.5 1 1 1 2 2 2 1 Toprim-like DUF1104 PF06518.6 KFX94087.1 - 0.031 14.4 4.3 3.1 8.0 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3349 PF11829.3 KFX94087.1 - 0.086 13.2 0.4 28 5.2 0.0 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KFX94087.1 - 0.3 10.7 1.8 1.3 8.7 0.1 2.8 2 2 2 4 4 4 0 EF hand RloB PF13707.1 KFX94087.1 - 0.46 10.1 5.7 24 4.5 3.8 2.3 1 1 0 1 1 1 0 RloB-like protein Glyco_hydro_47 PF01532.15 KFX94088.1 - 1.3e-170 567.9 0.0 1.6e-170 567.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MSP1a PF11670.3 KFX94089.1 - 0.066 13.0 0.9 0.13 12.0 0.5 1.7 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) Sugar_tr PF00083.19 KFX94092.1 - 4.5e-88 295.8 28.9 5.1e-88 295.6 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94092.1 - 4.1e-27 94.8 43.6 1.4e-26 93.0 17.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX94092.1 - 1.7e-06 26.5 2.7 3.3e-06 25.6 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0060 PF02694.10 KFX94092.1 - 0.021 14.8 0.4 0.021 14.8 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF2530 PF10745.4 KFX94092.1 - 0.24 11.4 9.2 12 6.0 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Glyco_hydro_3 PF00933.16 KFX94093.1 - 1.1e-68 231.3 0.0 1.5e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX94093.1 - 1.7e-56 191.2 0.1 2.6e-56 190.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX94093.1 - 3.7e-22 78.0 5.4 4.1e-22 77.8 0.6 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KFX94093.1 - 0.016 14.1 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF11 PF01345.13 KFX94093.1 - 0.89 9.6 7.8 1.6 8.8 2.2 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF11 GMC_oxred_N PF00732.14 KFX94094.1 - 1.9e-48 165.1 0.0 3.6e-48 164.2 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX94094.1 - 1.8e-38 132.0 0.1 3.1e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX94094.1 - 6.5e-05 21.9 2.4 0.00089 18.2 1.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX94094.1 - 0.00012 21.0 0.5 0.0068 15.3 0.6 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX94094.1 - 0.00028 20.8 0.1 0.00084 19.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX94094.1 - 0.00088 19.2 0.6 0.0028 17.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX94094.1 - 0.001 18.1 1.3 0.0028 16.6 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KFX94094.1 - 0.002 17.2 0.4 0.0074 15.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KFX94094.1 - 0.011 15.8 0.4 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX94094.1 - 0.034 13.9 0.4 0.11 12.2 0.3 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KFX94094.1 - 0.072 11.5 0.2 0.18 10.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 KFX94094.1 - 0.13 12.3 0.2 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Ank_2 PF12796.2 KFX94095.1 - 3e-25 88.3 0.7 2.1e-08 34.3 0.8 5.2 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX94095.1 - 9.2e-21 73.4 7.1 1e-08 35.1 0.0 6.1 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX94095.1 - 1.3e-18 66.9 6.0 1.4e-05 25.4 0.2 7.9 5 2 3 8 8 7 4 Ankyrin repeats (many copies) Ank PF00023.25 KFX94095.1 - 3.6e-13 48.5 6.3 0.00017 21.2 0.1 7.4 8 0 0 8 8 8 2 Ankyrin repeat Ank_3 PF13606.1 KFX94095.1 - 1.4e-12 46.5 3.3 0.051 13.8 0.0 9.0 10 0 0 10 10 8 2 Ankyrin repeat AAA_16 PF13191.1 KFX94095.1 - 7e-06 26.1 0.0 1.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KFX94095.1 - 1e-05 24.7 0.2 0.00042 19.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 KFX94095.1 - 0.00071 19.7 0.0 0.0076 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 KFX94095.1 - 0.0013 18.6 0.0 0.02 14.7 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFX94095.1 - 0.0016 18.1 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 KFX94095.1 - 0.0024 17.5 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain LCAT PF02450.10 KFX94095.1 - 0.0027 16.7 0.0 0.052 12.5 0.0 2.1 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase FtsK_SpoIIIE PF01580.13 KFX94095.1 - 0.0049 16.3 0.0 0.29 10.5 0.0 2.9 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA PF00004.24 KFX94095.1 - 0.0099 16.0 0.7 0.33 11.1 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFX94095.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FANCI_S2 PF14676.1 KFX94095.1 - 0.049 13.5 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 1 0 FANCI solenoid 2 AAA_25 PF13481.1 KFX94095.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX94095.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain p450 PF00067.17 KFX94096.1 - 7.2e-61 206.1 0.0 8.6e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 KFX94097.1 - 6.5e-20 71.1 34.9 1.2e-19 70.2 24.2 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Oxidored_q1_C PF01010.14 KFX94097.1 - 0.028 13.9 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Glyco_hydro_28 PF00295.12 KFX94099.1 - 2.6e-45 154.8 11.0 3.2e-45 154.5 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.3 KFX94099.1 - 0.0089 15.4 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KFX94099.1 - 0.031 14.0 18.1 0.5 10.1 12.5 2.7 1 1 0 1 1 1 0 Right handed beta helix region Pectinesterase PF01095.14 KFX94100.1 - 8.7e-47 159.1 7.0 1.1e-46 158.7 4.8 1.1 1 0 0 1 1 1 1 Pectinesterase HSP70 PF00012.15 KFX94101.1 - 0.0072 14.2 0.0 0.013 13.3 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein YjeF_N PF03853.10 KFX94103.1 - 7e-36 123.3 0.0 9.5e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KFX94103.1 - 2e-08 34.7 0.0 3.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 FDF domain RAI1 PF08652.6 KFX94110.1 - 2.6e-26 91.1 0.0 4.9e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease FA_hydroxylase PF04116.8 KFX94111.1 - 4.2e-12 46.4 26.2 5.2e-12 46.1 12.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Lysozyme_like PF13702.1 KFX94111.1 - 0.027 13.9 0.3 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 Lysozyme-like NLE PF08154.7 KFX94112.1 - 6.1e-21 74.2 0.5 9.1e-21 73.6 0.4 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.27 KFX94112.1 - 0.0013 18.5 3.2 0.0035 17.1 0.1 2.8 2 1 2 4 4 4 1 WD domain, G-beta repeat Aa_trans PF01490.13 KFX94113.1 - 2.5e-82 276.5 33.0 3e-82 276.2 22.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 KFX94114.1 - 1.3e-56 191.9 36.0 1.7e-56 191.5 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF899 PF05988.7 KFX94115.1 - 5.7e-45 153.3 0.0 7.6e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) DNA_pol_E_B PF04042.11 KFX94116.1 - 2.5e-50 170.6 0.0 3.3e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3445 PF11927.3 KFX94118.1 - 7.3e-72 241.7 0.0 8.9e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Acetyltransf_3 PF13302.1 KFX94119.1 - 3.7e-21 75.7 0.0 7.5e-21 74.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFX94119.1 - 1.3e-05 25.0 0.1 0.023 14.6 0.1 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX94119.1 - 0.0028 17.3 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 KFX94119.1 - 0.0043 17.0 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Pec_lyase_C PF00544.14 KFX94120.1 - 3.5e-20 72.3 5.1 6.4e-20 71.4 3.5 1.4 1 0 0 1 1 1 1 Pectate lyase Fe-ADH PF00465.14 KFX94126.1 - 1.4e-61 208.1 0.0 2e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Zds_C PF08632.5 KFX94126.1 - 3.2e-30 103.2 0.8 6.2e-30 102.3 0.6 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Fe-ADH_2 PF13685.1 KFX94126.1 - 6.9e-12 45.2 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase adh_short PF00106.20 KFX94127.1 - 5.7e-19 68.6 0.0 9.9e-19 67.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX94127.1 - 4.9e-09 36.0 0.0 8.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX94127.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX94127.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dfp1_Him1_M PF08630.5 KFX94128.1 - 2.1e-45 153.5 0.0 3.8e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KFX94128.1 - 8e-24 83.0 0.5 8e-24 83.0 0.4 1.9 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.2 KFX94128.1 - 0.0091 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Peptidase_M24 PF00557.19 KFX94129.1 - 5.5e-49 166.5 0.0 7.6e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFX94129.1 - 2.1e-37 127.5 0.0 3.5e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.15 KFX94129.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Creatinase_N PF01321.13 KFX94129.1 - 0.028 14.9 0.0 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain APG12 PF04110.8 KFX94130.1 - 1.2e-29 102.3 0.0 1.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KFX94130.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Lipoprotein_21 PF14041.1 KFX94130.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.6 2 0 0 2 2 2 1 LppP/LprE lipoprotein Pantoate_transf PF02548.10 KFX94131.1 - 6.6e-105 349.9 0.2 7.8e-105 349.6 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KFX94131.1 - 5.5e-07 29.0 0.7 7.2e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NanE PF04131.9 KFX94131.1 - 0.2 10.6 2.3 8.5 5.2 0.0 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase UQ_con PF00179.21 KFX94132.1 - 9.8e-18 63.9 0.0 1.3e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HMG_CoA_synt_C PF08540.5 KFX94134.1 - 3.4e-100 335.1 0.0 4.7e-100 334.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFX94134.1 - 1.5e-92 307.8 0.2 2.4e-92 307.2 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal SAP PF02037.22 KFX94135.1 - 4.6e-14 51.5 0.0 7e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KFX94135.1 - 0.00092 18.7 0.4 0.0033 16.9 0.3 1.9 1 1 0 1 1 1 1 HeH/LEM domain Armet PF10208.4 KFX94135.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Dicty_CAR PF05462.6 KFX94136.1 - 6.5e-17 61.3 8.6 1.1e-16 60.6 6.0 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KFX94136.1 - 3.6e-08 32.8 0.0 5.8e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFX94136.1 - 2.5e-06 27.2 11.3 4.2e-06 26.4 7.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.12 KFX94136.1 - 0.091 11.5 13.7 9.8 4.8 9.5 2.3 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF2207 PF09972.4 KFX94136.1 - 1.6 7.1 6.5 16 3.9 2.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2217 PF10265.4 KFX94140.1 - 0.39 9.4 7.9 0.49 9.0 5.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TRAM_LAG1_CLN8 PF03798.11 KFX94141.1 - 8.5e-35 120.1 14.5 1.8e-34 119.0 10.1 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KFX94141.1 - 2.1e-19 68.7 0.0 4.4e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein GDC-P PF02347.11 KFX94146.1 - 1.8e-178 593.6 0.0 2.7e-167 556.8 0.0 2.8 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFX94146.1 - 1.1e-06 28.0 0.1 1.9e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFX94146.1 - 0.044 12.8 0.2 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ank_2 PF12796.2 KFX94147.1 - 2.3e-17 63.0 0.0 1.7e-07 31.4 0.0 3.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94147.1 - 8.6e-17 60.0 0.4 1.1e-05 24.9 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFX94147.1 - 4e-15 55.4 2.1 6.1e-09 35.8 0.2 4.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94147.1 - 1.4e-14 52.6 0.1 0.0017 18.3 0.0 6.3 4 2 2 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFX94147.1 - 3.5e-08 33.7 3.9 0.047 14.2 0.0 5.9 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 KFX94148.1 - 5.9e-08 32.6 0.0 8.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX94148.1 - 4.3e-05 23.5 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX94148.1 - 0.015 15.3 0.0 0.075 13.1 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX94148.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SH3_4 PF06347.8 KFX94149.1 - 0.069 12.7 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain ALAD PF00490.16 KFX94150.1 - 2.1e-99 332.4 0.0 2.3e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase MFS_1 PF07690.11 KFX94165.1 - 5.1e-11 41.8 9.7 5.1e-11 41.8 6.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Glycos_transf_1 PF00534.15 KFX94166.1 - 9.4e-34 116.2 0.0 2.1e-33 115.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFX94166.1 - 2.5e-08 33.8 0.0 1.5e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KFX94166.1 - 3e-08 33.9 0.2 3e-08 33.9 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KFX94166.1 - 1.8e-07 31.2 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX94166.1 - 6.2e-07 29.6 0.2 8e-05 22.8 0.1 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 zf-C2H2 PF00096.21 KFX94174.1 - 5.5e-07 29.5 19.3 7.8e-06 25.9 2.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX94174.1 - 1.4e-05 25.1 3.8 1.4e-05 25.1 2.7 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX94174.1 - 0.00028 21.0 0.9 0.00028 21.0 0.6 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX94174.1 - 0.00046 20.2 1.0 0.00046 20.2 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX94174.1 - 0.038 14.1 1.0 0.17 12.1 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KFX94174.1 - 5.2 7.4 6.5 0.74 10.1 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-TRAF PF02176.13 KFX94174.1 - 5.7 7.3 9.9 0.14 12.5 1.9 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger ARS2 PF04959.8 KFX94174.1 - 8.2 6.5 11.7 1.3e+02 2.6 8.0 2.6 1 1 0 1 1 1 0 Arsenite-resistance protein 2 Ank_2 PF12796.2 KFX94175.1 - 1.8e-41 140.3 1.1 5.7e-11 42.6 0.2 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94175.1 - 5.9e-35 117.3 8.8 9.7e-06 25.1 0.1 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 KFX94175.1 - 5e-29 97.4 1.2 0.0003 20.7 0.0 9.2 9 0 0 9 9 8 5 Ankyrin repeat Ank_4 PF13637.1 KFX94175.1 - 1.5e-27 95.4 1.1 6.7e-05 23.2 0.0 6.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX94175.1 - 6.5e-25 86.5 3.1 7e-10 38.8 0.6 5.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) AAA_16 PF13191.1 KFX94175.1 - 4e-07 30.2 0.0 1.2e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFX94175.1 - 2.6e-06 27.2 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 KFX94175.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_17 PF13207.1 KFX94175.1 - 0.001 19.8 0.0 0.0041 17.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX94175.1 - 0.0066 16.1 0.0 0.032 13.9 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KFX94175.1 - 0.0069 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX94175.1 - 0.0087 16.1 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KFX94175.1 - 0.017 14.7 0.0 0.048 13.3 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 KFX94175.1 - 0.018 14.4 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 KFX94175.1 - 0.019 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Arch_ATPase PF01637.13 KFX94175.1 - 0.02 14.6 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 KFX94175.1 - 0.022 14.4 0.0 0.17 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KFX94175.1 - 0.031 13.9 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KFX94175.1 - 0.034 12.9 0.0 0.063 12.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 KFX94175.1 - 0.038 13.4 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFX94175.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFX94175.1 - 0.059 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFX94175.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Lipase_GDSL_3 PF14606.1 KFX94175.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UFD1 PF03152.9 KFX94176.1 - 9.3e-27 93.2 0.0 4.2e-21 74.8 0.0 3.4 3 1 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 Methyltransf_22 PF13383.1 KFX94177.1 - 1.7e-14 53.9 0.1 5.4e-07 29.3 0.1 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.7 KFX94177.1 - 5.3e-05 23.2 0.0 7.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain GCIP PF13324.1 KFX94178.1 - 2e-06 27.2 0.9 3.5e-06 26.4 0.3 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting BUD22 PF09073.5 KFX94178.1 - 0.02 13.9 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 BUD22 WHG PF13305.1 KFX94178.1 - 0.067 13.7 0.3 1.5 9.4 0.0 3.0 3 1 0 3 3 3 0 WHG domain CENP-B_dimeris PF09026.5 KFX94178.1 - 4.3 7.6 9.0 9.4 6.5 6.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Actin PF00022.14 KFX94179.1 - 6.3e-100 334.3 0.0 7.8e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Actin BPL_N PF09825.4 KFX94180.1 - 4.5e-138 460.0 0.0 5.8e-138 459.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KFX94180.1 - 2e-21 76.2 0.1 3.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KFX94180.1 - 0.08 12.6 0.1 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF2250 PF10007.4 KFX94180.1 - 0.15 11.9 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) CHCH PF06747.8 KFX94181.1 - 3.4e-05 23.6 8.8 5.5e-05 22.9 6.1 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 KFX94181.1 - 0.036 14.0 2.0 0.054 13.5 1.4 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFX94181.1 - 0.12 12.1 8.6 2.4 7.9 6.0 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KFX94181.1 - 0.34 10.9 4.1 0.46 10.5 2.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Mgm101p PF06420.7 KFX94182.1 - 3.7e-92 306.2 0.0 5.1e-92 305.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Rtf2 PF04641.7 KFX94184.1 - 2.9e-57 193.8 1.8 3.3e-57 193.6 1.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KFX94184.1 - 8.7e-05 21.9 0.0 0.0029 17.0 0.0 2.5 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFX94184.1 - 0.012 15.3 1.2 0.04 13.6 0.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFX94184.1 - 0.03 13.9 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Relaxase PF03432.9 KFX94184.1 - 0.034 13.5 0.4 0.059 12.7 0.3 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain zf-RING_5 PF14634.1 KFX94184.1 - 0.12 12.0 0.1 0.35 10.6 0.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain FAT PF02259.18 KFX94185.1 - 3.4e-131 437.4 1.4 3.4e-131 437.4 1.0 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 KFX94185.1 - 4.6e-63 211.9 4.7 2.2e-59 199.9 0.9 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KFX94185.1 - 3e-60 203.6 0.4 5.4e-60 202.7 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KFX94185.1 - 9.3e-43 144.3 2.4 1.7e-42 143.5 0.1 2.7 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 KFX94185.1 - 2.4e-21 75.7 9.9 0.00034 20.8 0.1 9.0 5 2 4 10 10 10 7 HEAT repeats HEAT PF02985.17 KFX94185.1 - 2.2e-17 61.5 11.9 0.00039 20.2 0.0 11.1 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 KFX94185.1 - 6e-14 52.0 12.4 1e-05 25.8 0.0 10.5 9 3 3 12 12 10 2 HEAT-like repeat FATC PF02260.15 KFX94185.1 - 9.9e-13 47.2 0.1 2.5e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 FATC domain Adaptin_N PF01602.15 KFX94185.1 - 3.5e-07 28.9 9.7 0.029 12.7 5.4 4.8 3 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 KFX94185.1 - 9.3e-06 25.1 1.2 0.23 10.7 0.0 5.2 5 1 0 5 5 5 1 CLASP N terminal Apc3 PF12895.2 KFX94185.1 - 0.0047 17.0 2.2 4.9 7.3 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.2 KFX94185.1 - 0.099 12.0 4.8 5 6.5 0.0 4.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.1 KFX94185.1 - 0.1 12.4 4.2 5.8 6.9 0.2 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KFX94186.1 - 1.5e-61 207.7 0.0 1.9e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pex24p PF06398.6 KFX94188.1 - 8.4e-96 320.8 0.5 1e-95 320.6 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PAP_assoc PF03828.14 KFX94189.1 - 8.4e-11 41.6 0.0 2.3e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFX94189.1 - 5.9e-07 29.7 0.0 1.4e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Thioredoxin PF00085.15 KFX94197.1 - 9.6e-33 111.9 0.1 1.3e-26 92.2 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KFX94197.1 - 1.6e-10 41.0 1.5 3.3e-07 30.3 0.0 2.5 3 0 0 3 3 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFX94197.1 - 3.3e-07 30.4 4.2 0.00034 20.7 0.2 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFX94197.1 - 2.5e-06 27.4 0.1 0.00062 19.8 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KFX94197.1 - 0.018 15.0 0.0 0.06 13.3 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 KFX94197.1 - 0.018 14.7 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.1 KFX94197.1 - 0.03 14.1 0.0 0.77 9.6 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain X PF00739.14 KFX94197.1 - 0.12 12.2 0.1 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Trans-activation protein X DUF1510 PF07423.6 KFX94197.1 - 0.71 9.2 11.4 1.3 8.3 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4551 PF15087.1 KFX94197.1 - 1.8 6.8 5.6 3.1 6.0 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NARP1 PF12569.3 KFX94197.1 - 1.9 7.1 12.6 2.9 6.5 8.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF605 PF04652.11 KFX94198.1 - 6.1e-99 331.9 16.1 7e-99 331.7 11.1 1.0 1 0 0 1 1 1 1 Vta1 like N-Term_TEN PF11474.3 KFX94198.1 - 0.056 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Peptidase_M28 PF04389.12 KFX94199.1 - 5.5e-17 62.0 0.0 1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KFX94199.1 - 1.4e-16 60.2 0.0 2.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KFX94199.1 - 9e-05 22.1 0.2 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 KFX94199.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.11 KFX94200.1 - 3.2e-36 124.7 33.0 3.8e-28 98.2 3.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX94200.1 - 8.9e-08 31.1 10.6 8.9e-08 31.1 7.4 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFX94200.1 - 0.0083 14.3 0.7 0.0083 14.3 0.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aconitase_C PF00694.14 KFX94214.1 - 3.1e-27 95.2 0.0 1.2e-26 93.3 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain YCII PF03795.9 KFX94215.1 - 0.00044 20.3 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain Cut8_C PF08559.5 KFX94216.1 - 4.8e-49 165.8 0.0 7.1e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KFX94216.1 - 9.5e-17 60.5 1.9 1.1e-16 60.2 0.3 2.0 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 KFX94216.1 - 5.9e-09 35.7 1.7 5.9e-09 35.7 1.2 1.9 2 0 0 2 2 2 1 Cut8 proteasome-binding domain CK2S PF15011.1 KFX94216.1 - 0.065 13.0 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF2408 PF10303.4 KFX94217.1 - 9.9e-48 161.6 0.3 1.9e-25 89.5 0.1 4.8 4 1 0 4 4 4 4 Protein of unknown function (DUF2408) DUF1664 PF07889.7 KFX94217.1 - 0.001 18.8 0.6 0.025 14.3 0.1 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) PolyG_pol PF01518.11 KFX94217.1 - 0.001 17.6 0.1 0.0018 16.8 0.1 1.2 1 0 0 1 1 1 1 Sigma NS protein Phage_term_smal PF05944.7 KFX94217.1 - 0.0045 16.6 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 Phage small terminase subunit COG6 PF06419.6 KFX94217.1 - 0.016 13.4 1.0 0.034 12.2 0.2 1.9 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Laminin_II PF06009.7 KFX94217.1 - 0.021 14.5 1.6 0.069 12.8 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II HR1 PF02185.11 KFX94217.1 - 0.1 12.3 1.2 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat Nop14 PF04147.7 KFX94217.1 - 0.38 8.6 2.7 1.2 6.9 0.1 1.6 1 1 1 2 2 2 0 Nop14-like family Ribosomal_60s PF00428.14 KFX94218.1 - 3.5e-24 85.0 8.9 5e-24 84.5 6.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pex19 PF04614.7 KFX94220.1 - 9.9e-75 251.3 14.5 9.9e-75 251.3 10.0 1.9 1 1 1 2 2 2 1 Pex19 protein family DUF162 PF02589.10 KFX94220.1 - 0.00035 20.1 0.3 0.0007 19.1 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YkgG family COG1556 Vps4_C PF09336.5 KFX94220.1 - 0.024 14.5 0.2 0.097 12.5 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain FliE PF02049.13 KFX94220.1 - 0.029 14.3 2.6 0.029 14.3 1.8 3.4 3 1 1 4 4 4 0 Flagellar hook-basal body complex protein FliE FliG_N PF14842.1 KFX94220.1 - 0.24 11.5 3.8 0.19 11.8 0.4 2.6 3 0 0 3 3 3 0 FliG N-terminal domain DUF3782 PF12644.2 KFX94220.1 - 1.8 8.4 5.5 50 3.7 3.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) UQ_con PF00179.21 KFX94221.1 - 7.7e-49 164.7 0.0 8.6e-49 164.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX94221.1 - 0.0032 17.2 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFX94221.1 - 0.13 12.2 0.4 0.18 11.7 0.3 1.6 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.16 KFX94222.1 - 3.1e-69 233.2 0.0 4.3e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFX94222.1 - 1.5e-35 121.6 0.0 2.5e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFX94222.1 - 1.3e-29 102.8 0.0 2.8e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFX94222.1 - 1.3e-09 37.5 0.0 2.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KFX94222.1 - 0.0004 19.1 0.0 0.013 14.2 0.0 2.6 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KFX94222.1 - 0.0015 17.4 0.0 0.0048 15.8 0.0 1.8 1 1 0 1 1 1 1 NAD synthase BRX_N PF13713.1 KFX94222.1 - 0.085 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain IBR PF01485.16 KFX94223.1 - 0.00038 20.2 65.6 0.00044 20.0 9.1 6.5 5 3 0 5 5 5 2 IBR domain Fer2_3 PF13085.1 KFX94223.1 - 0.025 14.4 0.7 0.025 14.4 0.5 2.9 2 1 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain DUF1712 PF08217.6 KFX94224.1 - 1.1e-15 57.0 0.0 4e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 KFX94225.1 - 3.1e-22 78.9 0.0 4.7e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Mago-bind PF09282.5 KFX94225.1 - 0.095 12.2 0.2 0.23 11.0 0.2 1.7 1 0 0 1 1 1 0 Mago binding WD40 PF00400.27 KFX94226.1 - 2.4e-48 160.3 23.8 2.4e-11 43.0 0.0 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX94226.1 - 3.4e-07 28.8 7.6 0.047 11.8 0.1 4.9 3 1 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 KFX94226.1 - 0.00064 19.4 0.8 0.056 13.1 0.0 3.2 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KFX94226.1 - 0.0036 15.5 0.0 0.0062 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 KFX94226.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.1 KFX94226.1 - 0.051 13.0 0.1 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Hira PF07569.6 KFX94226.1 - 0.082 12.1 0.4 5.6 6.1 0.0 3.0 1 1 2 3 3 3 0 TUP1-like enhancer of split Spc7 PF08317.6 KFX94227.1 - 0.04 12.5 1.1 0.08 11.5 0.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 KFX94227.1 - 0.3 10.8 3.1 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.4 KFX94227.1 - 3.2 7.8 12.5 2.4 8.2 0.4 3.7 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 KFX94227.1 - 4.1 6.9 6.2 0.95 9.0 0.9 2.1 2 0 0 2 2 2 0 IncA protein Ly49 PF08391.5 KFX94227.1 - 8.4 6.5 6.7 0.79 9.8 0.9 2.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region UPF0542 PF15086.1 KFX94228.1 - 0.013 15.2 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 SUR7 PF06687.7 KFX94229.1 - 6.3e-30 104.3 12.3 7.8e-30 104.0 8.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KFX94229.1 - 0.0027 17.4 3.6 0.65 9.6 1.7 2.4 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 KFX94229.1 - 0.034 13.5 5.3 1.7 8.0 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UPF0233 PF06781.7 KFX94229.1 - 0.49 10.0 5.1 3.2 7.4 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) HILPDA PF15220.1 KFX94229.1 - 1.8 8.5 7.2 0.11 12.5 0.8 2.1 2 1 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated DUF4231 PF14015.1 KFX94229.1 - 3.1 7.8 5.6 5 7.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Helicase_C PF00271.26 KFX94230.1 - 9.6e-10 38.1 0.2 1.6e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GRP PF07172.6 KFX94230.1 - 0.76 10.2 23.0 0.44 11.0 14.9 1.4 1 1 0 1 1 1 0 Glycine rich protein family DUF3628 PF12300.3 KFX94230.1 - 2.8 7.9 6.0 3.3 7.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) FoP_duplication PF13865.1 KFX94230.1 - 3.1 8.2 5.2 1.7 9.1 1.9 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 F_actin_cap_B PF01115.12 KFX94232.1 - 1.5e-103 345.2 0.0 1.7e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit BNR_assoc_N PF14873.1 KFX94233.1 - 0.13 11.9 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of BNR-repeat neuraminidase Epimerase PF01370.16 KFX94234.1 - 2.8e-21 76.0 0.0 4.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX94234.1 - 1.5e-09 37.2 0.1 2.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFX94234.1 - 4.1e-08 33.4 0.1 1.4e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX94234.1 - 8e-07 29.1 0.0 2.2e-06 27.6 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KFX94234.1 - 1e-05 24.4 0.0 1.7e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFX94234.1 - 0.0028 17.3 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KFX94234.1 - 0.0087 15.0 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.18 KFX94234.1 - 0.016 14.9 0.0 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFX94234.1 - 0.053 12.5 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Topoisom_I_N PF02919.10 KFX94235.1 - 6.1e-96 319.8 1.1 6.1e-96 319.8 0.8 4.0 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFX94235.1 - 2.1e-85 285.5 4.2 2.1e-85 285.5 2.9 2.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFX94235.1 - 2.6e-31 107.0 0.2 9e-31 105.3 0.2 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KFX94235.1 - 0.032 13.3 0.1 0.073 12.2 0.1 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family Ribosomal_S15 PF00312.17 KFX94235.1 - 2.4 7.9 7.5 0.37 10.5 0.9 2.9 2 0 0 2 2 2 0 Ribosomal protein S15 ATP-synt PF00231.14 KFX94236.1 - 3.1e-69 233.5 9.8 3.6e-69 233.3 6.8 1.0 1 0 0 1 1 1 1 ATP synthase NT5C PF06941.7 KFX94236.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Beta-Casp PF10996.3 KFX94236.1 - 0.054 13.4 0.2 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 Beta-Casp domain DUF4325 PF14213.1 KFX94236.1 - 0.065 12.8 0.1 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4325) ChiC PF06483.6 KFX94236.1 - 0.071 12.8 1.2 0.15 11.8 0.1 2.0 2 1 0 2 2 2 0 Chitinase C E1-E2_ATPase PF00122.15 KFX94237.1 - 9.7e-62 208.0 3.9 2e-61 207.0 2.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX94237.1 - 1.9e-36 125.2 2.9 1.9e-36 125.2 2.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX94237.1 - 3.6e-29 102.7 0.0 7.1e-28 98.4 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX94237.1 - 1.4e-22 79.4 0.0 3.6e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFX94237.1 - 5.4e-12 44.9 0.0 1.7e-11 43.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFX94237.1 - 4.8e-11 43.1 0.1 1.6e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase BAH PF01426.13 KFX94237.1 - 1.7e-06 27.7 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain Hydrolase_3 PF08282.7 KFX94237.1 - 1.9e-05 24.3 0.4 0.0034 17.0 0.3 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-RING-like PF08746.6 KFX94237.1 - 0.2 11.6 3.8 0.56 10.2 2.7 1.8 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.11 KFX94255.1 - 7e-22 77.6 62.5 9.2e-21 73.9 24.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX94255.1 - 1e-05 24.1 21.7 0.0068 14.8 7.7 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1469 PF07332.6 KFX94255.1 - 6.4 6.5 7.5 10 5.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) PAP_central PF04928.12 KFX94256.1 - 3.5e-105 350.4 0.0 4.7e-105 349.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KFX94256.1 - 1.1e-46 158.1 0.1 2.9e-46 156.8 0.1 1.8 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KFX94256.1 - 2.6e-07 30.8 0.1 6.8e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TRAP_alpha PF03896.11 KFX94256.1 - 3.5 6.5 6.8 5.7 5.8 4.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sec63 PF02889.11 KFX94257.1 - 9.2e-45 153.2 0.0 4.3e-44 150.9 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KFX94257.1 - 9e-17 60.5 1.3 2e-16 59.4 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KFX94257.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Nol1_Nop2_Fmu PF01189.12 KFX94259.1 - 1.1e-14 54.5 0.1 4.4e-09 36.1 0.0 3.5 2 1 0 2 2 2 2 NOL1/NOP2/sun family Pkinase PF00069.20 KFX94261.1 - 8.4e-77 257.8 0.0 9.5e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94261.1 - 1.1e-35 122.9 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX94261.1 - 0.012 14.6 0.0 0.028 13.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 KFX94261.1 - 0.083 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SSrecog PF03531.9 KFX94262.1 - 1.6e-74 250.0 1.7 1.8e-73 246.5 1.2 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFX94262.1 - 1.3e-24 86.0 0.0 1.1e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 KFX94262.1 - 0.058 12.5 6.0 0.069 12.3 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain HSP90 PF00183.13 KFX94263.1 - 8.5e-252 836.2 31.5 1e-251 836.0 21.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KFX94263.1 - 7.1e-11 41.9 0.2 7.1e-11 41.9 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFX94263.1 - 8.7e-11 41.5 0.1 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KFX94263.1 - 0.05 13.9 0.4 0.05 13.9 0.3 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1676) Flavin_Reduct PF01613.13 KFX94264.1 - 9.4e-26 90.5 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.13 KFX94265.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.5 KFX94266.1 - 7.1e-85 284.0 2.5 1.2e-84 283.2 1.7 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KFX94266.1 - 1.1e-23 83.2 0.0 2.2e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 KFX94266.1 - 0.0079 15.1 0.5 0.013 14.4 0.4 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFX94266.1 - 0.023 14.2 3.4 0.036 13.5 2.4 1.3 1 0 0 1 1 1 0 BAR domain Med11 PF10280.4 KFX94267.1 - 3.5e-31 107.6 0.1 4.3e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 KFX94268.1 - 1.7e-55 183.0 27.7 4.2e-12 45.4 2.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFX94268.1 - 1e-41 142.3 0.7 1.6e-41 141.7 0.5 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nucleoporin_N PF08801.6 KFX94268.1 - 2.6e-06 26.4 0.3 0.3 9.7 0.0 3.7 2 2 2 4 4 4 2 Nup133 N terminal like LisH PF08513.6 KFX94268.1 - 7.1e-05 22.4 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 KFX94268.1 - 0.00032 18.9 6.9 0.015 13.4 0.4 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 EBP PF05241.7 KFX94269.1 - 0.00013 21.0 0.2 0.00013 21.0 0.2 1.8 2 1 0 2 2 2 1 Emopamil binding protein Scs3p PF10261.4 KFX94270.1 - 1.3e-63 214.2 1.2 1.7e-63 213.8 0.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Pex14_N PF04695.8 KFX94270.1 - 0.19 11.7 1.6 0.37 10.8 1.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.17 KFX94271.1 - 5.2e-57 191.7 0.0 6.2e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX94271.1 - 4.9e-19 68.9 0.0 6.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX94271.1 - 6.9e-14 51.4 0.0 8.8e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX94271.1 - 6.4e-07 28.7 0.0 7.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX94271.1 - 6.3e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX94271.1 - 0.00045 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFX94271.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain BetaGal_dom4_5 PF13364.1 KFX94271.1 - 0.04 14.1 0.1 0.31 11.3 0.0 2.3 2 1 0 2 2 2 0 Beta-galactosidase jelly roll domain AAA_22 PF13401.1 KFX94271.1 - 0.09 12.9 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.8 KFX94271.1 - 0.64 7.7 5.7 0.86 7.3 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Kri1_C PF12936.2 KFX94272.1 - 1.2e-29 102.0 1.0 1.2e-29 102.0 0.7 3.3 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 KFX94272.1 - 2.8e-23 82.1 16.3 2.8e-23 82.1 11.3 5.4 5 2 1 6 6 6 1 KRI1-like family Clr2 PF10383.4 KFX94280.1 - 1.8e-06 28.0 0.0 4.5e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 Sec61_beta PF03911.11 KFX94281.1 - 8.6e-20 70.2 2.3 8.6e-20 70.2 1.6 1.9 2 0 0 2 2 2 1 Sec61beta family NIF PF03031.13 KFX94282.1 - 4.4e-51 172.6 0.2 7.7e-51 171.9 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 KFX94283.1 - 2.8e-15 55.5 0.2 0.0079 16.0 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFX94283.1 - 0.00011 20.6 0.0 0.00018 19.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Sel1 PF08238.7 KFX94284.1 - 3.3e-41 138.7 33.5 2.6e-05 24.6 0.3 12.5 12 1 1 13 13 13 9 Sel1 repeat TPR_7 PF13176.1 KFX94284.1 - 0.00033 20.2 3.5 59 3.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 KFX94284.1 - 0.17 12.1 0.2 0.4 11.0 0.2 1.5 1 0 0 1 1 1 0 Snapin/Pallidin TPR_17 PF13431.1 KFX94284.1 - 0.55 10.5 6.9 7.5 7.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 KFX94285.1 - 1.2e-27 96.6 0.0 2e-27 95.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Rad1 PF02144.11 KFX94287.1 - 5.4e-83 277.9 0.9 7e-83 277.5 0.6 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.20 KFX94288.1 - 6e-26 90.1 0.5 1.2e-25 89.2 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFX94288.1 - 1.9e-09 37.5 0.1 4.8e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX94288.1 - 4.9e-09 36.0 0.2 1.1e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFX94288.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ABC_membrane_2 PF06472.10 KFX94289.1 - 1.9e-95 319.2 1.8 2.2e-93 312.4 0.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFX94289.1 - 3.3e-14 53.3 0.0 9.3e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KFX94289.1 - 0.08 12.4 0.0 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain CTDII PF01556.13 KFX94290.1 - 2.9e-20 71.9 4.3 1.4e-17 63.3 0.2 2.5 3 0 0 3 3 3 2 DnaJ C terminal domain Glyco_hydro_18 PF00704.23 KFX94292.1 - 5.7e-53 180.5 3.7 9.9e-53 179.7 2.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFX94292.1 - 4e-08 33.0 1.8 0.013 15.4 0.0 4.1 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.14 KFX94292.1 - 5.1e-06 26.3 4.7 5.1e-06 26.3 3.2 2.8 2 0 0 2 2 2 1 Chitin recognition protein Varsurf_PPLC PF03490.8 KFX94292.1 - 0.001 18.6 0.1 0.0033 17.0 0.0 1.9 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C DUF3142 PF11340.3 KFX94292.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) Methyltransf_10 PF05971.7 KFX94299.1 - 1.9e-35 122.4 0.0 2.5e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 KFX94299.1 - 0.00095 19.7 0.0 0.0023 18.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KFX94299.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MAP PF03642.8 KFX94299.1 - 0.026 14.7 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 MAP domain Met_10 PF02475.11 KFX94299.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.7 KFX94299.1 - 0.041 14.3 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KFX94299.1 - 0.057 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KFX94299.1 - 0.088 13.2 0.0 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KFX94299.1 - 0.093 12.3 0.0 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.1 KFX94299.1 - 0.14 13.0 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.2 KFX94300.1 - 8.4e-69 227.9 6.9 7.8e-21 74.2 0.0 6.7 5 1 1 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94300.1 - 6.6e-62 202.3 23.9 1e-07 31.3 0.0 12.4 12 1 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 KFX94300.1 - 2.1e-49 165.0 8.0 1.5e-09 38.0 0.0 9.6 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94300.1 - 8.8e-39 127.6 16.3 2.2e-06 27.3 0.0 12.2 12 1 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 KFX94300.1 - 1.1e-34 117.5 16.5 1.1e-07 31.7 0.3 8.5 7 2 2 9 9 9 8 Ankyrin repeats (many copies) F-box-like PF12937.2 KFX94300.1 - 0.006 16.2 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like GLTP PF08718.6 KFX94301.1 - 5.2e-46 156.3 0.0 6.4e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PLDc PF00614.17 KFX94302.1 - 5.2e-15 54.6 2.5 2.3e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFX94302.1 - 2.6e-12 46.5 0.0 2e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Sugar_tr PF00083.19 KFX94303.1 - 2.7e-33 115.2 25.3 7e-33 113.8 17.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94303.1 - 1.3e-27 96.4 29.8 3.3e-21 75.4 9.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Ldh_1_N PF00056.18 KFX94304.1 - 1.1e-44 151.6 0.1 3.6e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFX94304.1 - 7.6e-41 139.7 0.2 1.2e-40 139.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KFX94304.1 - 0.024 13.3 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2OG-FeII_Oxy PF03171.15 KFX94305.1 - 2.4e-06 27.7 0.0 4.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KFX94305.1 - 5.6e-06 26.8 0.0 9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFX94305.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_1_2 PF00155.16 KFX94321.1 - 3.4e-59 200.6 0.0 3.8e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_17 PF13207.1 KFX94322.1 - 3.6e-06 27.7 0.0 1.2e-05 26.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 KFX94322.1 - 3.3e-05 23.5 0.0 5.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KFX94322.1 - 0.00017 21.9 0.0 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KFX94322.1 - 0.028 13.9 0.0 0.059 12.9 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KFX94322.1 - 0.044 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFX94322.1 - 0.069 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CoaE PF01121.15 KFX94322.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_16 PF13191.1 KFX94322.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 KFX94322.1 - 0.16 10.5 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Gly_transf_sug PF04488.10 KFX94325.1 - 4e-13 49.6 0.0 8.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TPR_16 PF13432.1 KFX94327.1 - 0.2 12.3 1.9 0.31 11.7 0.8 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat C2 PF00168.25 KFX94336.1 - 7.7e-14 51.3 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain ICL PF00463.16 KFX94337.1 - 2.5e-280 930.1 1.2 2.9e-280 929.9 0.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFX94337.1 - 4.2e-12 45.8 0.1 2.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2753 PF10952.3 KFX94338.1 - 0.033 14.1 0.0 0.45 10.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2753) DUF972 PF06156.8 KFX94340.1 - 0.078 13.3 0.6 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KFX94340.1 - 2.7 7.5 5.3 5 6.6 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Mid2 PF04478.7 KFX94341.1 - 8.6e-06 25.2 1.4 8.6e-06 25.2 1.0 2.5 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.5 KFX94341.1 - 0.025 12.9 4.4 0.034 12.5 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SKG6 PF08693.5 KFX94341.1 - 0.097 12.0 0.2 0.097 12.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain FixQ PF05545.6 KFX94341.1 - 0.24 11.0 1.9 0.44 10.2 1.3 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF605 PF04652.11 KFX94341.1 - 0.26 10.6 28.5 0.41 9.9 19.7 1.3 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 KFX94341.1 - 0.72 8.0 10.0 0.99 7.5 6.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.12 KFX94341.1 - 4.5 5.9 5.9 6.1 5.5 4.1 1.4 1 0 0 1 1 1 0 Presenilin ketoacyl-synt PF00109.21 KFX94349.1 - 4.1e-32 111.6 0.1 9.4e-30 103.9 0.1 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF3470 PF11953.3 KFX94349.1 - 0.13 11.8 0.0 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3470) DUF1777 PF08648.7 KFX94350.1 - 0.13 11.9 28.9 0.54 9.9 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) APG6 PF04111.7 KFX94350.1 - 1.7 7.6 8.2 2.8 6.8 5.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2040 PF09745.4 KFX94351.1 - 8.6e-37 125.8 17.4 8.6e-37 125.8 12.0 3.1 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) LDB19 PF13002.2 KFX94352.1 - 2.1e-12 46.9 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KFX94352.1 - 0.013 15.2 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF2492 PF10678.4 KFX94363.1 - 0.091 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) DUF1220 PF06758.8 KFX94363.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) Suc_Fer-like PF06999.7 KFX94366.1 - 1e-38 133.6 0.0 1.2e-38 133.4 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Hydrolase PF00702.21 KFX94367.1 - 5.5e-17 62.9 0.0 5.1e-16 59.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFX94367.1 - 2.2e-14 53.0 0.0 1.1e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFX94367.1 - 4.8e-10 39.9 0.6 1.3e-09 38.5 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX94367.1 - 0.00022 21.1 0.0 0.00075 19.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX94367.1 - 0.00083 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.2 KFX94368.1 - 1.1e-95 320.7 0.0 1.5e-95 320.1 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFX94368.1 - 1.7e-32 111.8 0.0 3.6e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region NYD-SP28_assoc PF14775.1 KFX94368.1 - 0.58 9.9 0.2 28 4.5 0.0 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain FAD_binding_4 PF01565.18 KFX94369.1 - 7.2e-18 64.4 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-DNL PF05180.7 KFX94370.1 - 1.6e-05 24.5 0.1 3e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger SBP PF03110.9 KFX94370.1 - 1.2 9.3 4.3 1.2 9.3 1.0 2.3 2 1 0 2 2 2 0 SBP domain Pkinase PF00069.20 KFX94372.1 - 2.5e-69 233.3 0.0 4.6e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_2b PF00587.20 KFX94372.1 - 5.2e-65 218.2 0.0 8.4e-65 217.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase_Tyr PF07714.12 KFX94372.1 - 1.1e-51 175.4 0.2 2.7e-51 174.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KFX94372.1 - 5.6e-22 77.9 0.1 2e-21 76.1 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain HGTP_anticodon PF03129.15 KFX94372.1 - 1.1e-18 66.9 0.0 4.5e-18 64.9 0.0 2.2 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.1 KFX94372.1 - 6.3e-07 28.6 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 KFX94372.1 - 7.6e-05 22.9 0.0 0.0002 21.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 KFX94372.1 - 0.0032 17.2 2.3 0.0069 16.1 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFX94372.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Brix PF04427.13 KFX94373.1 - 8.8e-20 71.1 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Brix domain AMPKBI PF04739.10 KFX94373.1 - 0.27 11.1 1.8 8.7 6.2 1.2 2.6 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain SH3_1 PF00018.23 KFX94377.1 - 3.9e-05 22.9 0.0 3.9e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFX94377.1 - 0.0069 15.9 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GFA PF04828.9 KFX94378.1 - 1.7e-18 66.3 0.0 2.4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KFX94378.1 - 0.53 9.8 0.0 0.53 9.8 0.0 2.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Lar_restr_allev PF14354.1 KFX94378.1 - 0.89 9.9 3.9 21 5.5 0.8 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 KFX94378.1 - 1.9 7.8 10.5 0.64 9.3 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain ADH_N PF08240.7 KFX94379.1 - 1.5e-28 98.6 2.0 3.3e-28 97.6 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX94379.1 - 1.1e-20 73.5 0.1 2.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KFX94379.1 - 0.00093 18.8 0.8 0.0027 17.3 0.2 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KFX94379.1 - 0.0036 16.9 2.3 0.012 15.2 0.3 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFX94379.1 - 0.011 14.8 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 KFX94379.1 - 0.028 15.3 0.0 0.071 13.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PalH PF08733.5 KFX94383.1 - 4.5e-77 259.2 1.4 6.9e-77 258.6 1.0 1.3 1 0 0 1 1 1 1 PalH/RIM21 DUF418 PF04235.7 KFX94383.1 - 1.1 8.8 8.2 1 9.0 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF418) Sugar_tr PF00083.19 KFX94393.1 - 1.8e-62 211.4 30.0 2.2e-62 211.1 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94393.1 - 6.6e-13 48.1 38.9 2.3e-06 26.5 11.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_10 PF13374.1 KFX94394.1 - 1.3e-43 145.7 4.6 1.3e-12 47.1 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFX94394.1 - 1.6e-37 127.2 2.6 5e-16 58.4 0.0 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX94394.1 - 1.1e-12 46.7 5.3 0.017 14.8 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX94394.1 - 7.4e-09 35.1 3.9 0.3 11.3 0.1 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat NACHT PF05729.7 KFX94394.1 - 2.3e-08 33.8 0.0 5.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.1 KFX94394.1 - 2.9e-08 34.1 0.3 0.011 16.3 0.2 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KFX94394.1 - 9.7e-08 31.7 2.5 3.4 8.3 0.1 5.2 4 1 1 5 5 4 1 Tetratricopeptide repeat Dynamin_N PF00350.18 KFX94394.1 - 2.1e-06 27.6 0.0 5.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family TPR_1 PF00515.23 KFX94394.1 - 6.4e-06 25.5 5.8 1.2 8.8 0.0 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX94394.1 - 2.3e-05 23.9 5.2 2.6 8.1 0.0 5.5 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX94394.1 - 3.7e-05 23.2 0.5 0.017 14.7 0.0 3.7 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.1 KFX94394.1 - 4.4e-05 22.9 0.8 3.6 7.5 0.0 4.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX94394.1 - 0.00051 20.3 2.0 9 6.7 0.0 4.4 1 1 2 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 KFX94394.1 - 0.0012 18.8 0.4 0.02 14.8 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_14 PF13428.1 KFX94394.1 - 0.0029 18.0 2.4 20 6.1 0.5 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 KFX94394.1 - 0.017 15.3 0.5 38 4.9 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 KFX94394.1 - 0.028 14.8 1.6 3.8 8.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_helicase PF00910.17 KFX94394.1 - 0.056 13.6 0.0 0.56 10.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 KFX94394.1 - 0.095 12.4 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KFX94394.1 - 0.11 12.6 0.1 0.9 9.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 KFX94394.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KFX94397.1 - 1.8e-42 144.9 0.0 2.7e-21 76.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX94397.1 - 3.6e-41 141.3 23.5 1.9e-21 76.7 7.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region T2SE PF00437.15 KFX94397.1 - 9.3e-10 37.8 0.2 0.00031 19.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KFX94397.1 - 4.8e-09 35.6 0.3 0.0016 17.8 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KFX94397.1 - 1.4e-08 34.2 0.5 0.002 17.3 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFX94397.1 - 2e-07 31.1 0.1 0.019 15.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX94397.1 - 2.8e-07 30.2 0.1 0.003 17.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_21 PF13304.1 KFX94397.1 - 4.3e-07 30.1 0.3 0.84 9.5 0.0 4.0 3 1 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KFX94397.1 - 5.5e-07 29.7 0.7 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KFX94397.1 - 2.5e-06 27.9 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX94397.1 - 4.3e-06 26.6 0.0 0.081 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFX94397.1 - 4.4e-06 27.5 0.1 0.18 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX94397.1 - 6.8e-06 25.3 0.4 0.061 12.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KFX94397.1 - 7.9e-06 26.3 0.1 0.06 13.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Arch_ATPase PF01637.13 KFX94397.1 - 4.1e-05 23.3 0.5 0.37 10.4 0.0 3.7 4 0 0 4 4 4 1 Archaeal ATPase AAA_25 PF13481.1 KFX94397.1 - 4.8e-05 22.8 0.6 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX94397.1 - 5.1e-05 23.1 0.0 0.45 10.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KFX94397.1 - 9.4e-05 22.7 0.2 0.78 10.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KFX94397.1 - 0.0001 21.8 1.7 0.19 11.1 0.1 2.7 3 0 0 3 3 2 2 AAA-like domain cobW PF02492.14 KFX94397.1 - 0.00012 21.5 1.6 0.062 12.7 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KFX94397.1 - 0.00012 22.0 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KFX94397.1 - 0.00018 20.6 0.7 0.44 9.6 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin NTPase_1 PF03266.10 KFX94397.1 - 0.00028 20.6 0.2 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 NTPase MobB PF03205.9 KFX94397.1 - 0.00055 19.6 0.6 0.53 9.9 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KFX94397.1 - 0.001 18.9 0.5 0.52 10.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family ABC_ATPase PF09818.4 KFX94397.1 - 0.0011 17.6 0.5 0.57 8.6 0.0 3.6 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 KFX94397.1 - 0.0014 18.2 0.3 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain Adeno_IVa2 PF02456.10 KFX94397.1 - 0.0015 17.2 0.1 0.13 10.9 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein DAP3 PF10236.4 KFX94397.1 - 0.0019 17.1 2.9 0.89 8.4 0.1 3.2 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 KFX94397.1 - 0.0024 17.5 3.1 0.77 9.3 0.1 3.2 3 0 0 3 3 2 1 NACHT domain Viral_helicase1 PF01443.13 KFX94397.1 - 0.0059 16.1 0.1 3 7.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 KFX94397.1 - 0.007 15.0 0.3 1.3 7.5 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 KFX94397.1 - 0.0083 15.7 1.0 0.2 11.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 KFX94397.1 - 0.012 14.9 0.2 4.9 6.3 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.17 KFX94397.1 - 0.021 15.0 0.0 6 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.8 KFX94397.1 - 0.021 13.7 0.3 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KFX94397.1 - 0.021 13.9 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MutS_V PF00488.16 KFX94397.1 - 0.025 13.9 0.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 MutS domain V ATP_bind_1 PF03029.12 KFX94397.1 - 0.028 13.9 0.4 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 KFX94397.1 - 0.03 13.8 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KFX94397.1 - 0.037 13.7 1.2 19 4.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFX94397.1 - 0.044 13.3 0.1 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KFX94397.1 - 0.064 12.8 0.2 11 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFX94397.1 - 0.09 12.7 0.5 1 9.3 0.2 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KFX94397.1 - 0.09 12.9 0.2 3.1 8.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.4 KFX94397.1 - 0.097 11.1 0.2 0.82 8.0 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein PduV-EutP PF10662.4 KFX94397.1 - 0.14 11.6 2.5 12 5.3 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.15 KFX94397.1 - 0.14 11.7 0.8 3.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase GTP_EFTU PF00009.22 KFX94397.1 - 0.19 11.1 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 KFX94397.1 - 0.21 10.5 0.4 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Septin Guanylate_kin PF00625.16 KFX94397.1 - 0.3 10.5 0.5 4 6.8 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase Rad17 PF03215.10 KFX94397.1 - 0.32 9.6 1.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PRK PF00485.13 KFX94397.1 - 0.34 10.4 0.4 17 4.9 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 KFX94397.1 - 0.37 10.5 2.0 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2075 PF09848.4 KFX94397.1 - 0.38 9.6 0.0 6.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KFX94397.1 - 1 9.2 2.4 5.4 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain PHF5 PF03660.9 KFX94399.1 - 0.03 14.4 1.2 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 PHF5-like protein Transp_cyt_pur PF02133.10 KFX94402.1 - 5.6e-48 163.5 34.2 6.5e-48 163.3 23.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4149 PF13664.1 KFX94402.1 - 1.5 8.9 24.2 0.71 9.9 0.5 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4149) Na_sulph_symp PF00939.14 KFX94404.1 - 1.6e-19 70.1 33.3 8.4e-19 67.7 23.1 2.0 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFX94404.1 - 2.2e-07 29.7 34.1 3.3e-06 25.9 9.8 2.1 1 1 1 2 2 2 2 Citrate transporter SKG6 PF08693.5 KFX94404.1 - 6.9 6.0 11.3 0.2 11.0 2.0 3.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF488 PF04343.8 KFX94405.1 - 1.9e-18 66.9 0.0 4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF488 HLH PF00010.21 KFX94416.1 - 7.1e-16 57.6 0.0 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ISG65-75 PF11727.3 KFX94416.1 - 0.065 12.2 2.5 0.078 12.0 1.7 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Smac_DIABLO PF09057.5 KFX94416.1 - 0.092 11.8 3.4 0.13 11.3 2.4 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases DUF904 PF06005.7 KFX94416.1 - 0.33 11.2 1.9 1.3 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 KFX94421.1 - 0.091 12.9 0.2 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.8 KFX94426.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) PHD PF00628.24 KFX94426.1 - 0.055 13.1 11.5 0.17 11.6 8.0 1.8 1 1 0 1 1 1 0 PHD-finger DOCK-C2 PF14429.1 KFX94427.1 - 2.4e-28 98.9 0.0 4.4e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFX94427.1 - 6e-10 38.7 0.1 1.8e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KFX94427.1 - 0.0002 20.7 0.0 0.0004 19.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX94427.1 - 0.00088 18.8 0.0 0.0063 16.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain ADH_N PF08240.7 KFX94428.1 - 2.2e-09 37.0 0.0 6.2e-09 35.6 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX94428.1 - 1.3e-06 29.3 0.0 6.2e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX94428.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Biotin_lipoyl PF00364.17 KFX94428.1 - 0.027 14.0 1.9 0.63 9.7 0.0 2.6 3 0 0 3 3 3 0 Biotin-requiring enzyme Acyl_transf_3 PF01757.17 KFX94429.1 - 2.8e-31 108.6 38.0 1.1e-30 106.7 26.3 1.8 1 1 0 1 1 1 1 Acyltransferase family DUF4239 PF14023.1 KFX94429.1 - 0.38 10.0 2.1 7.7 5.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Isochorismatase PF00857.15 KFX94438.1 - 8.3e-20 71.4 0.0 1.3e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family DUF2427 PF10348.4 KFX94438.1 - 6.2e-07 28.9 3.2 1.7e-06 27.5 2.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF2306 PF10067.4 KFX94438.1 - 2.9 8.0 13.9 0.6 10.2 1.1 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Zn_clus PF00172.13 KFX94439.1 - 5.1e-10 39.0 12.1 1e-09 38.1 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX94439.1 - 1.1e-07 31.0 0.2 2.5e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prion PF00377.13 KFX94439.1 - 0.041 13.6 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain RGP PF03214.8 KFX94439.1 - 0.045 12.4 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide DUF4441 PF14536.1 KFX94439.1 - 0.12 12.3 1.4 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) Unstab_antitox PF09720.5 KFX94439.1 - 0.29 10.8 3.0 0.26 10.9 0.2 2.4 2 0 0 2 2 2 0 Putative addiction module component p450 PF00067.17 KFX94440.1 - 3.7e-45 154.3 0.0 6.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2263 PF10021.4 KFX94440.1 - 2.1e-23 82.9 0.0 4.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KFX94440.1 - 0.018 14.9 0.0 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 Macro domain Zip PF02535.17 KFX94441.1 - 9.3e-47 159.5 2.7 1.4e-46 158.9 1.9 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter p450 PF00067.17 KFX94442.1 - 4.3e-69 233.2 0.0 6e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3505 PF12013.3 KFX94442.1 - 1.7e-22 79.6 0.8 3.7e-22 78.6 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 KFX94442.1 - 4.4e-05 22.2 0.1 7.9e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 KFX94443.1 - 2.2e-12 46.9 0.0 3.5e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX94443.1 - 5e-09 36.3 0.0 6.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KFX94443.1 - 4.5e-05 22.1 0.0 0.00024 19.7 0.0 2.1 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KFX94443.1 - 4.8e-05 22.6 0.0 0.00023 20.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.6 KFX94443.1 - 9.6e-05 21.1 0.0 0.00016 20.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 KFX94443.1 - 0.00048 19.6 0.0 0.00084 18.8 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KFX94443.1 - 0.00085 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 KFX94443.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Carn_acyltransf PF00755.15 KFX94444.1 - 8e-94 314.8 0.0 9.9e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KFX94444.1 - 6.4e-47 160.4 0.0 1.1e-46 159.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 KFX94444.1 - 4.2e-07 30.1 0.0 6.5e-06 26.3 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Alpha-amylase PF00128.19 KFX94445.1 - 3.2e-66 223.8 0.0 4.2e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KFX94445.1 - 5.1e-18 64.9 0.4 1.9e-17 63.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_15 PF00723.16 KFX94446.1 - 5.6e-99 331.7 0.2 6.4e-99 331.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GMC_oxred_N PF00732.14 KFX94447.1 - 8.3e-25 87.5 0.0 8.7e-24 84.1 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX94447.1 - 8.4e-20 71.5 0.0 2e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX94447.1 - 5.8e-09 35.2 0.0 1.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX94447.1 - 1.1e-05 24.5 0.6 0.00016 20.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX94447.1 - 0.00049 20.2 0.2 0.077 13.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX94447.1 - 0.0018 18.2 0.3 0.0058 16.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX94447.1 - 0.0047 17.3 0.2 0.21 12.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX94447.1 - 0.0049 15.3 0.1 0.0078 14.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFX94447.1 - 0.0075 16.1 0.2 0.027 14.3 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX94447.1 - 0.093 11.7 0.8 0.15 11.0 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Chitin_bind_3 PF03067.10 KFX94448.1 - 5.5e-09 36.5 0.0 1.1e-05 25.7 0.0 2.3 1 1 0 2 2 2 2 Chitin binding domain Omega-toxin PF06357.6 KFX94448.1 - 2.6 7.7 7.9 1.1 8.8 2.9 2.2 2 0 0 2 2 2 0 Omega-atracotoxin adh_short PF00106.20 KFX94449.1 - 3.6e-15 56.2 0.0 5.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX94449.1 - 5.2e-08 32.7 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX94449.1 - 0.00038 19.9 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFX94449.1 - 0.042 13.6 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HeLo PF14479.1 KFX94450.1 - 3.6e-14 53.0 0.0 3.9e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Ank PF00023.25 KFX94451.1 - 1.7e-08 33.8 0.3 7.1e-08 31.8 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KFX94451.1 - 2.8e-07 30.7 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX94451.1 - 6.8e-07 29.3 0.1 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX94451.1 - 2.5e-06 27.8 0.2 0.00038 20.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94451.1 - 2.8e-05 23.9 0.0 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Cupin_2 PF07883.6 KFX94452.1 - 0.006 16.0 4.1 0.64 9.5 0.1 3.4 3 1 0 3 3 3 2 Cupin domain PMI_typeI PF01238.16 KFX94452.1 - 0.0081 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomannose isomerase type I JmjC PF02373.17 KFX94452.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Glyco_hydro_2 PF00703.16 KFX94453.1 - 4.4e-09 36.7 0.0 1.2e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFX94453.1 - 9.8e-07 28.4 0.1 2.8e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFX94453.1 - 0.0026 16.7 0.1 0.0053 15.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 KFX94454.1 - 2.5e-76 257.0 23.7 4.1e-76 256.3 16.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94454.1 - 1.7e-16 59.8 21.0 1.7e-16 59.8 14.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KFX94455.1 - 7.6e-08 32.1 12.2 1.4e-07 31.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX94455.1 - 3.5e-06 25.8 6.2 2.2e-05 23.2 4.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Apc3 PF12895.2 KFX94455.1 - 0.04 14.0 0.8 11 6.2 0.2 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Metallophos_2 PF12850.2 KFX94456.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KFX94456.1 - 0.00011 21.6 1.2 0.00034 20.0 0.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pyridox_oxidase PF01243.15 KFX94457.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.1 KFX94474.1 - 1.4e-52 175.4 1.6 4.7e-09 36.0 0.0 13.4 10 2 4 14 14 14 10 PPR repeat family PPR PF01535.15 KFX94474.1 - 8.7e-26 88.0 17.6 0.0002 21.0 0.0 13.5 15 0 0 15 15 15 5 PPR repeat PPR_1 PF12854.2 KFX94474.1 - 6.2e-25 86.3 0.1 5.8e-08 32.0 0.0 9.4 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.1 KFX94474.1 - 5.4e-24 82.4 20.4 0.018 15.3 0.0 14.8 14 1 1 15 15 15 7 Pentatricopeptide repeat domain RPM2 PF08579.6 KFX94474.1 - 8.8e-05 22.6 0.1 0.0036 17.4 0.0 3.6 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.1 KFX94474.1 - 0.0056 16.9 2.9 0.89 9.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX94474.1 - 0.007 16.9 9.0 1.2 9.9 0.0 7.2 10 0 0 10 10 10 1 Tetratricopeptide repeat DUF846 PF05832.7 KFX94478.1 - 0.063 12.9 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) zf-CCCH PF00642.19 KFX94480.1 - 0.00043 19.8 0.9 0.00043 19.8 0.6 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDP-OH_P_transf PF01066.16 KFX94481.1 - 2.8e-17 62.8 4.2 2.8e-17 62.8 2.9 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SRP19 PF01922.12 KFX94482.1 - 3.4e-28 98.0 0.0 5.9e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Het-C PF07217.6 KFX94483.1 - 4.5e-281 933.4 0.0 5.2e-281 933.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.23 KFX94484.1 - 1e-18 66.8 0.3 4.3e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.8 KFX94484.1 - 0.013 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Flu_M1 PF00598.14 KFX94484.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Zn_clus PF00172.13 KFX94495.1 - 8.8e-07 28.7 9.7 1.4e-06 28.0 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GBP_repeat PF02526.9 KFX94495.1 - 0.18 11.2 1.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Glycophorin-binding protein APG5 PF04106.7 KFX94496.1 - 2.9e-36 124.7 0.0 3.4e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 Sugar_tr PF00083.19 KFX94498.1 - 3.6e-73 246.6 13.2 4.1e-73 246.4 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94498.1 - 4.6e-30 104.5 12.6 7e-30 103.9 8.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX94498.1 - 1.3e-06 27.1 16.1 0.00092 17.7 0.2 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX94498.1 - 0.00075 17.8 0.3 0.00075 17.8 0.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.14 KFX94499.1 - 1.3e-14 54.0 0.0 1.3e-07 31.0 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX94499.1 - 0.0011 18.9 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX94499.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCHC PF00098.18 KFX94500.1 - 3.4e-10 39.3 4.7 3.7e-07 29.7 1.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 KFX94500.1 - 0.1 12.1 1.9 0.2 11.1 0.3 2.1 2 0 0 2 2 2 0 Zinc knuckle Rad51 PF08423.6 KFX94501.1 - 1e-116 388.3 0.0 1.4e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KFX94501.1 - 1.3e-10 40.8 0.0 1.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KFX94501.1 - 4.2e-09 36.0 0.0 6.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFX94501.1 - 1.5e-06 27.5 0.0 3.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 KFX94501.1 - 0.0035 17.4 3.1 0.0046 17.0 0.3 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix domain DUF2173 PF09941.4 KFX94501.1 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) RNA_pol_A_CTD PF03118.10 KFX94501.1 - 0.037 13.4 0.3 0.11 11.8 0.3 1.7 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Ald_Xan_dh_C PF01315.17 KFX94501.1 - 0.082 12.9 0.2 4.8 7.2 0.0 2.6 3 0 0 3 3 3 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DnaB_C PF03796.10 KFX94501.1 - 0.09 11.6 0.0 0.39 9.5 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RRP7 PF12923.2 KFX94502.1 - 6.3e-36 123.2 10.9 6.3e-36 123.2 7.5 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) CsbD PF05532.7 KFX94503.1 - 6.1e-15 54.6 28.6 7.7e-08 31.8 6.8 3.2 3 0 0 3 3 3 3 CsbD-like Aminotran_5 PF00266.14 KFX94504.1 - 1.4e-94 316.9 0.0 1.7e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFX94504.1 - 5.7e-08 32.2 0.0 9.3e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFX94504.1 - 0.00011 21.3 0.0 0.00032 19.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KFX94504.1 - 0.0024 16.3 0.0 0.0039 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain G6PD_C PF02781.11 KFX94519.1 - 8.4e-135 448.2 0.0 1.5e-134 447.4 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFX94519.1 - 5e-66 222.4 0.2 8.7e-66 221.6 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 KFX94519.1 - 0.0066 15.9 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.13 KFX94524.1 - 1e-42 143.7 0.7 1.2e-42 143.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KFX94524.1 - 0.0093 15.8 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain VMA21 PF09446.5 KFX94525.1 - 9.7e-15 54.2 10.4 1.5e-14 53.6 7.2 1.3 1 0 0 1 1 1 1 VMA21-like domain Ank_2 PF12796.2 KFX94529.1 - 1.2e-84 278.8 23.2 3.6e-21 75.3 2.0 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94529.1 - 2.8e-51 168.8 16.6 2.7e-08 33.2 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 KFX94529.1 - 7.2e-41 137.8 21.6 4e-10 39.9 0.1 7.2 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94529.1 - 1.2e-38 127.2 13.0 2.6e-06 27.1 0.1 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFX94529.1 - 3.2e-32 109.8 15.4 9.3e-09 35.2 0.0 6.7 4 3 3 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.7 KFX94529.1 - 2.4e-08 33.8 0.0 5.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX94529.1 - 2.7e-05 24.3 1.5 0.0003 20.9 0.0 3.2 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 KFX94529.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 KFX94529.1 - 0.047 14.5 0.1 0.43 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ribosomal_S6 PF01250.12 KFX94529.1 - 0.072 12.9 0.0 4.5 7.2 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein S6 Thiolase_N PF00108.18 KFX94534.1 - 1.5e-76 256.9 0.6 2.9e-76 255.9 0.4 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX94534.1 - 1.6e-41 140.5 1.1 3.7e-41 139.3 0.8 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Zn_clus PF00172.13 KFX94550.1 - 1.2e-07 31.5 13.6 1.7e-07 31.0 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF92 PF01940.11 KFX94550.1 - 0.11 11.5 0.2 3.1 6.8 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF92 MAGE_N PF12440.3 KFX94550.1 - 0.33 11.2 4.4 0.55 10.5 3.1 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal E1-E2_ATPase PF00122.15 KFX94551.1 - 1.8e-38 131.8 10.6 1.8e-38 131.8 7.4 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX94551.1 - 1.5e-28 100.7 0.0 2.7e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX94551.1 - 1.8e-16 60.9 0.0 3.9e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFX94551.1 - 8.8e-08 32.1 0.0 1.3e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KFX94551.1 - 3.6e-05 23.4 0.4 0.005 16.4 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.19 KFX94553.1 - 8.7e-27 94.1 15.0 1.3e-26 93.5 10.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KFX94553.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF2403 PF10290.4 KFX94569.1 - 3.1e-26 91.3 0.0 4.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) RhoGAP PF00620.22 KFX94572.1 - 4.2e-42 143.3 0.0 8.4e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Hid1 PF12722.2 KFX94572.1 - 0.22 9.1 2.9 0.35 8.4 2.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoporin_C PF03177.9 KFX94573.1 - 1e-119 400.7 1.3 1.3e-119 400.3 0.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFX94573.1 - 1.5e-94 317.1 0.3 3.5e-94 315.9 0.2 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Pkinase PF00069.20 KFX94573.1 - 5.4e-69 232.2 0.0 1.1e-68 231.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94573.1 - 8.3e-33 113.5 0.0 1.5e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFX94573.1 - 7.8e-07 29.5 0.2 2.4e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFX94573.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3802 PF12290.3 KFX94573.1 - 0.058 13.6 0.4 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Peptidase_M41 PF01434.13 KFX94591.1 - 5.7e-71 238.3 4.3 8.7e-70 234.5 2.5 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 KFX94591.1 - 4.6e-42 143.3 0.0 1.2e-41 141.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX94591.1 - 1.4e-05 25.1 0.7 0.00014 21.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KFX94591.1 - 2.3e-05 23.2 0.0 4.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KFX94591.1 - 3.9e-05 23.4 0.0 0.00014 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX94591.1 - 4e-05 23.7 0.1 0.029 14.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX94591.1 - 0.00012 22.9 0.0 0.00029 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX94591.1 - 0.00049 19.2 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFX94591.1 - 0.00073 19.4 0.0 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX94591.1 - 0.002 17.8 0.4 0.0054 16.4 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFX94591.1 - 0.0022 17.4 0.1 0.0066 15.8 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFX94591.1 - 0.0047 16.3 1.1 0.08 12.3 0.4 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX94591.1 - 0.0091 15.1 1.1 0.026 13.6 0.3 2.0 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KFX94591.1 - 0.02 14.0 0.2 0.042 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KFX94591.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KFX94591.1 - 0.034 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KFX94591.1 - 0.068 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFX94591.1 - 0.098 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KFX94591.1 - 0.12 12.0 0.3 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Beta_protein PF14350.1 KFX94591.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Beta protein AAA_18 PF13238.1 KFX94591.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 KFX94592.1 - 5.4e-19 67.4 26.7 8e-08 32.2 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFX94592.1 - 8.9e-19 66.6 29.1 7.8e-05 22.7 1.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX94592.1 - 1.3e-09 37.7 27.1 0.0007 19.7 1.3 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX94592.1 - 0.012 15.6 12.5 1.6 8.9 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFX94592.1 - 0.017 15.4 1.1 0.017 15.4 0.7 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger ZF-HD_dimer PF04770.7 KFX94592.1 - 4.3 7.4 10.3 15 5.6 0.0 3.4 2 2 1 3 3 3 0 ZF-HD protein dimerisation region CHORD PF04968.7 KFX94592.1 - 6.6 7.0 15.2 5 7.4 0.1 4.4 2 2 2 4 4 4 0 CHORD Hexokinase_1 PF00349.16 KFX94601.1 - 1.8e-66 223.3 0.1 2.9e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KFX94601.1 - 2.2e-66 223.5 0.3 3.1e-66 223.0 0.2 1.2 1 0 0 1 1 1 1 Hexokinase Peptidase_A22B PF04258.8 KFX94603.1 - 1.2e-53 182.4 0.1 4.3e-53 180.6 0.1 1.7 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KFX94603.1 - 0.0014 17.8 14.2 0.06 12.4 6.7 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 KFX94603.1 - 0.16 10.7 1.7 0.85 8.3 0.2 2.5 3 0 0 3 3 3 0 Presenilin DUF1810 PF08837.6 KFX94603.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) Pro_isomerase PF00160.16 KFX94604.1 - 1.9e-49 167.8 0.0 2.1e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Acetyltransf_1 PF00583.19 KFX94605.1 - 0.00031 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family XPC-binding PF09280.6 KFX94612.1 - 0.0047 16.3 3.3 0.0047 16.3 2.3 2.4 2 1 0 2 2 2 1 XPC-binding domain ABC_tran PF00005.22 KFX94613.1 - 5.2e-34 117.4 0.1 1.4e-33 116.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KFX94613.1 - 7.5e-19 68.1 1.7 1.8e-18 66.9 1.2 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFX94613.1 - 1.2e-06 27.8 0.0 0.00011 21.5 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX94613.1 - 8.2e-06 25.9 0.7 0.0014 18.6 0.0 2.7 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX94613.1 - 0.00059 19.8 0.1 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFX94613.1 - 0.002 17.3 0.0 0.0056 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX94613.1 - 0.0032 16.9 0.2 0.0095 15.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX94613.1 - 0.0032 18.2 0.1 0.014 16.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KFX94613.1 - 0.004 17.2 0.1 0.019 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX94613.1 - 0.0045 17.2 0.5 0.04 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFX94613.1 - 0.0054 15.8 0.0 0.021 13.9 0.0 2.0 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.24 KFX94613.1 - 0.019 14.4 0.0 0.05 13.0 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KFX94613.1 - 0.022 14.4 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KFX94613.1 - 0.024 14.9 1.2 0.037 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KFX94613.1 - 0.034 13.7 1.0 0.75 9.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFX94613.1 - 0.042 13.7 0.3 0.22 11.4 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KFX94613.1 - 0.067 12.6 0.3 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KFX94613.1 - 0.086 12.2 0.1 0.99 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain YchF-GTPase_C PF06071.8 KFX94615.1 - 1.9e-33 114.1 0.3 4.3e-33 112.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KFX94615.1 - 3.1e-12 46.4 0.0 8.1e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX94615.1 - 0.00051 19.3 0.0 0.0015 17.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 KFX94615.1 - 0.00072 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 TGS domain MobB PF03205.9 KFX94615.1 - 0.027 14.1 0.4 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PPAK PF02818.10 KFX94615.1 - 0.043 13.7 2.2 0.11 12.3 1.5 1.7 1 0 0 1 1 1 0 PPAK motif AAA_14 PF13173.1 KFX94615.1 - 0.062 13.1 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFX94615.1 - 0.094 13.5 0.1 0.83 10.4 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFX94615.1 - 0.16 12.2 4.5 1.2 9.3 3.1 2.5 1 1 0 1 1 1 0 AAA domain Alg14 PF08660.6 KFX94619.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Pkinase PF00069.20 KFX94622.1 - 3e-66 223.2 0.0 4.6e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94622.1 - 6.2e-52 176.2 0.0 1.1e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KFX94622.1 - 2.3e-29 101.3 0.0 5.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KFX94622.1 - 8.8e-16 57.8 0.1 1.8e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX94622.1 - 2.8e-13 49.5 0.1 5.5e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KFX94622.1 - 1.7e-09 37.9 0.1 3.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KFX94622.1 - 2.3e-08 33.3 0.0 3e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like SAM_PNT PF02198.11 KFX94622.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Kdo PF06293.9 KFX94622.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MBOAT PF03062.14 KFX94623.1 - 3e-43 148.1 5.9 3e-43 148.1 4.1 1.9 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 KFX94624.1 - 1.2e-152 509.4 0.3 1.4e-152 509.2 0.2 1.0 1 0 0 1 1 1 1 Sec1 family GARS_A PF01071.14 KFX94625.1 - 3.8e-85 284.3 0.2 5.6e-84 280.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KFX94625.1 - 5e-37 126.3 0.4 3.2e-36 123.7 0.0 2.6 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KFX94625.1 - 6.1e-33 113.9 0.0 3.1e-32 111.7 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KFX94625.1 - 3.4e-26 91.2 0.1 1.1e-25 89.6 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KFX94625.1 - 8.7e-17 61.1 2.8 3.5e-16 59.2 1.1 2.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KFX94625.1 - 4e-12 46.2 0.0 1.2e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX94625.1 - 2.6e-08 32.9 0.0 5.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFX94625.1 - 5.9e-06 25.7 0.0 1.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFX94625.1 - 1.6e-05 24.2 0.1 4.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 KFX94625.1 - 0.00093 19.0 0.0 0.0034 17.2 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFX94625.1 - 0.011 15.1 0.0 0.034 13.5 0.0 1.9 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.5 KFX94625.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 KFX94625.1 - 0.021 14.3 0.2 0.06 12.8 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain RRM_6 PF14259.1 KFX94625.1 - 0.075 13.0 0.2 1.6 8.7 0.0 3.1 3 1 1 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1282 PF06930.7 KFX94628.1 - 0.0024 17.5 0.2 0.0026 17.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) MARVEL PF01284.18 KFX94628.1 - 0.014 15.2 0.7 0.017 14.9 0.5 1.1 1 0 0 1 1 1 0 Membrane-associating domain Yip1 PF04893.12 KFX94628.1 - 0.024 14.1 1.9 0.027 13.9 1.3 1.1 1 0 0 1 1 1 0 Yip1 domain ABC_membrane PF00664.18 KFX94628.1 - 0.035 13.5 0.1 0.041 13.3 0.1 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region Tetraspannin PF00335.15 KFX94628.1 - 0.12 11.5 0.8 0.16 11.1 0.5 1.2 1 0 0 1 1 1 0 Tetraspanin family Cation_ATPase_C PF00689.16 KFX94628.1 - 0.18 11.3 1.0 1.3 8.5 0.5 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Sdh_cyt PF01127.17 KFX94628.1 - 3.2 7.6 6.5 6.2 6.6 4.5 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit O-FucT PF10250.4 KFX94629.1 - 1.2e-05 24.5 0.0 0.0055 15.8 0.0 2.9 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Tannase PF07519.6 KFX94631.1 - 2.9e-112 375.8 2.9 3.7e-112 375.4 2.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase MU117 PF15474.1 KFX94633.1 - 0.16 12.4 1.2 0.44 11.0 0.8 1.8 1 1 0 1 1 1 0 Meiotically up-regulated gene family RNase_H PF00075.19 KFX94635.1 - 2.7e-08 34.2 0.0 3.2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 RNase H BNR_2 PF13088.1 KFX94637.1 - 2.8e-29 102.2 0.8 4.7e-29 101.5 0.5 1.3 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFX94637.1 - 8.7e-11 39.9 24.7 0.046 13.5 0.4 5.9 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.1 KFX94637.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain Mis14 PF08641.7 KFX94649.1 - 4.6e-06 26.7 0.5 7.6e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like ORC6 PF05460.8 KFX94650.1 - 0.046 12.8 0.5 0.042 12.9 0.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SWI-SNF_Ssr4 PF08549.5 KFX94650.1 - 0.059 11.6 0.0 0.063 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AAA PF00004.24 KFX94651.1 - 1.6e-45 154.5 0.7 5.5e-45 152.7 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX94651.1 - 3.8e-09 36.3 0.6 1.2e-08 34.8 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX94651.1 - 4.2e-08 33.3 0.0 8.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFX94651.1 - 4.2e-07 30.1 0.0 1.4e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX94651.1 - 7.7e-07 29.3 0.6 0.001 19.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KFX94651.1 - 3e-06 26.3 0.0 5.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFX94651.1 - 0.00012 21.9 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFX94651.1 - 0.00029 19.9 0.0 0.00065 18.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFX94651.1 - 0.00033 21.4 0.0 0.0019 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFX94651.1 - 0.00043 20.2 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFX94651.1 - 0.00076 19.1 1.0 0.057 13.0 0.0 3.2 3 1 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 KFX94651.1 - 0.00092 18.8 0.1 0.04 13.5 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KFX94651.1 - 0.0011 18.0 0.0 0.0039 16.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFX94651.1 - 0.0013 18.4 0.2 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KFX94651.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 KFX94651.1 - 0.0031 17.2 0.0 0.0092 15.6 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_3 PF07726.6 KFX94651.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KFX94651.1 - 0.0049 15.6 0.0 0.0086 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 KFX94651.1 - 0.005 16.4 0.7 0.018 14.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.1 KFX94651.1 - 0.0055 17.0 0.7 0.9 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX94651.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFX94651.1 - 0.0058 16.0 0.7 0.054 12.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFX94651.1 - 0.0066 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFX94651.1 - 0.007 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KFX94651.1 - 0.0071 16.0 0.8 0.061 13.0 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 KFX94651.1 - 0.01 15.2 0.3 0.025 13.9 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFX94651.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KFX94651.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KFX94651.1 - 0.025 13.6 0.8 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 KFX94651.1 - 0.028 14.7 0.0 0.089 13.0 0.0 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 KFX94651.1 - 0.048 13.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFX94651.1 - 0.054 13.5 0.1 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 KFX94651.1 - 0.066 11.5 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 KFX94651.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KFX94651.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SHMT PF00464.14 KFX94652.1 - 4.6e-207 687.1 0.0 5.3e-207 686.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KFX94652.1 - 1.7e-05 23.7 0.0 2.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFX94652.1 - 7.1e-05 21.9 0.0 0.00016 20.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFX94652.1 - 0.0052 15.9 0.0 0.0084 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Baculo_DNA_bind PF04786.7 KFX94652.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein IL3 PF02059.10 KFX94652.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Interleukin-3 Nop PF01798.13 KFX94653.1 - 4.9e-60 201.1 0.1 9.1e-60 200.3 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFX94653.1 - 1.8e-25 88.5 0.1 4.8e-25 87.1 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFX94653.1 - 2.8e-21 75.4 0.0 2.8e-21 75.4 0.0 2.7 4 0 0 4 4 4 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 KFX94653.1 - 0.35 10.5 20.7 0.74 9.4 14.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA PF00004.24 KFX94654.1 - 4.1e-43 146.7 0.1 9.3e-43 145.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFX94654.1 - 8.6e-29 99.2 0.1 3e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KFX94654.1 - 3.3e-22 78.1 3.5 1e-21 76.5 2.4 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KFX94654.1 - 2.4e-06 28.3 0.2 2.4e-05 25.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KFX94654.1 - 4e-06 26.8 0.4 0.0024 17.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KFX94654.1 - 8.8e-06 25.8 0.0 0.0033 17.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFX94654.1 - 1.3e-05 24.9 0.0 4.5e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFX94654.1 - 2e-05 23.7 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KFX94654.1 - 2.8e-05 23.6 0.0 6.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFX94654.1 - 6.1e-05 22.4 0.3 0.21 10.9 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX94654.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFX94654.1 - 0.00015 20.6 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KFX94654.1 - 0.00023 21.0 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFX94654.1 - 0.0008 18.4 0.0 0.0029 16.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KFX94654.1 - 0.00086 19.3 0.0 0.01 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain USP8_dimer PF08969.6 KFX94654.1 - 0.00097 19.0 2.4 0.0021 17.9 1.6 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain RNA_helicase PF00910.17 KFX94654.1 - 0.0013 18.8 0.0 0.015 15.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 KFX94654.1 - 0.0074 15.4 0.0 0.018 14.2 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFX94654.1 - 0.0089 15.1 0.1 0.26 10.3 0.1 2.3 1 1 0 1 1 1 1 Zeta toxin Peptidase_M28 PF04389.12 KFX94654.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Arch_ATPase PF01637.13 KFX94654.1 - 0.035 13.7 0.2 1.6 8.3 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_24 PF13479.1 KFX94654.1 - 0.037 13.5 0.2 0.13 11.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 KFX94654.1 - 0.049 13.1 0.0 0.44 9.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KFX94654.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 KFX94654.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 KFX94654.1 - 0.092 13.0 0.2 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFX94654.1 - 0.093 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 KFX94654.1 - 0.11 11.9 0.3 0.88 8.9 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain KaiC PF06745.8 KFX94654.1 - 0.12 11.4 0.1 7.1 5.6 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_28 PF13521.1 KFX94654.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 KFX94658.1 - 1.6e-78 263.4 0.0 2.4e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX94658.1 - 1.5e-46 158.7 0.0 2.8e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFX94658.1 - 1e-32 112.5 0.3 3.5e-32 110.7 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 KFX94658.1 - 2.2e-15 56.5 0.0 4.4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KFX94658.1 - 2.4e-12 47.0 0.0 5.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 KFX94658.1 - 0.00059 20.2 0.2 0.0014 18.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFX94658.1 - 0.024 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KFX94658.1 - 0.03 14.2 0.2 0.08 12.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain PSRT PF07636.6 KFX94658.1 - 0.32 10.4 9.2 1.3 8.5 6.3 2.0 1 0 0 1 1 1 0 PSRT polyprenyl_synt PF00348.12 KFX94672.1 - 1.5e-71 240.2 0.0 1.8e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 KFX94673.1 - 4.9e-50 168.9 0.7 7.4e-49 165.1 0.1 2.1 2 0 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 DUF883 PF05957.8 KFX94675.1 - 0.0075 16.6 2.5 0.0075 16.6 1.7 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF4337 PF14235.1 KFX94675.1 - 0.012 15.5 0.6 0.02 14.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ETRAMP PF09716.5 KFX94675.1 - 0.013 15.4 1.0 0.024 14.5 0.7 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.1 KFX94675.1 - 0.057 12.8 10.4 0.024 14.0 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Secretogranin_V PF05281.6 KFX94675.1 - 0.058 12.7 0.3 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Cas_Csy4 PF09618.5 KFX94675.1 - 0.13 12.0 0.5 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) HSP70 PF00012.15 KFX94675.1 - 0.16 9.8 4.3 0.21 9.4 3.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Herpes_DNAp_acc PF04929.7 KFX94675.1 - 1.3 7.9 5.0 1.7 7.5 3.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor V-SNARE_C PF12352.3 KFX94676.1 - 1.2e-14 54.0 0.1 2.7e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFX94676.1 - 0.0001 21.8 0.4 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 1 Sec20 Baculo_PEP_C PF04513.7 KFX94676.1 - 0.075 12.8 1.9 0.2 11.4 1.0 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 KFX94676.1 - 0.51 10.0 4.6 0.61 9.8 2.2 1.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TPK_catalytic PF04263.11 KFX94677.1 - 3.2e-24 84.8 0.0 4.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KFX94677.1 - 8.7e-23 79.8 0.0 1.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Hydrolase PF00702.21 KFX94678.1 - 6.1e-23 82.3 0.0 3.2e-22 80.0 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX94678.1 - 3.6e-19 69.6 0.0 7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFX94678.1 - 1.8e-18 66.4 0.0 6.1e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFX94678.1 - 2e-06 27.6 0.1 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX94678.1 - 0.0042 16.6 0.5 0.033 13.7 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase FixQ PF05545.6 KFX94678.1 - 0.61 9.7 4.6 12 5.6 0.7 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4139 PF13598.1 KFX94679.1 - 4.9e-41 141.0 0.0 6.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) CHCH PF06747.8 KFX94681.1 - 9.1e-10 38.2 11.4 2.3e-08 33.7 1.4 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KFX94681.1 - 0.16 11.8 10.7 1.7 8.4 1.6 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KFX94681.1 - 0.81 9.7 7.1 1.4 9.0 3.2 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KFX94681.1 - 2.6 8.1 9.9 5.8 7.0 0.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb zf-H2C2 PF09337.5 KFX94687.1 - 4.8e-21 73.8 4.0 7.5e-21 73.2 2.8 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KFX94687.1 - 0.0003 20.7 0.0 0.00081 19.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KFX94687.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX94687.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX94687.1 - 0.034 13.8 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Imm47 PF15586.1 KFX94687.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 47 RINT1_TIP1 PF04437.8 KFX94688.1 - 1.2e-95 320.9 0.0 1.7e-95 320.4 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec34 PF04136.10 KFX94688.1 - 0.098 12.3 2.0 0.86 9.2 0.6 2.6 2 1 0 2 2 2 0 Sec34-like family DUF4164 PF13747.1 KFX94688.1 - 0.67 10.1 5.8 7.3 6.8 2.8 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DNA_ligase_A_M PF01068.16 KFX94689.1 - 9.5e-50 168.7 0.1 5.2e-47 159.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFX94689.1 - 5.7e-42 143.5 0.1 1.4e-41 142.2 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFX94689.1 - 1.9e-17 63.4 0.0 8.9e-17 61.2 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Sugar_tr PF00083.19 KFX94690.1 - 3.3e-41 141.3 30.5 3.8e-39 134.5 21.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94690.1 - 3.1e-27 95.2 32.1 1.2e-13 50.5 9.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.8 KFX94691.1 - 1e-25 91.0 0.0 1.3e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 KFX94691.1 - 0.00035 21.0 0.0 0.0008 19.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KFX94691.1 - 0.0012 19.0 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Glucosamine_iso PF01182.15 KFX94694.1 - 1.1e-25 90.5 0.0 1.8e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC2_membrane PF01061.19 KFX94695.1 - 1.8e-84 282.1 59.3 2.1e-46 157.7 13.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFX94695.1 - 2.6e-35 121.7 0.0 9.1e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFX94695.1 - 1.3e-27 95.4 6.3 6.8e-24 83.4 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KFX94695.1 - 6.7e-11 41.8 34.1 4.3e-07 29.2 10.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KFX94695.1 - 6.1e-07 29.4 0.1 1.9e-06 27.8 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KFX94695.1 - 1.8e-06 27.8 0.1 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX94695.1 - 2.9e-06 26.8 0.4 0.0054 16.1 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_17 PF13207.1 KFX94695.1 - 5.5e-06 27.1 0.0 0.0053 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFX94695.1 - 3.6e-05 23.8 0.1 0.11 12.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX94695.1 - 7.8e-05 22.1 0.5 0.007 15.8 0.2 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX94695.1 - 0.0003 20.9 0.0 0.14 12.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KFX94695.1 - 0.00048 19.6 0.8 0.013 14.9 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KFX94695.1 - 0.0005 20.0 0.2 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KFX94695.1 - 0.00076 18.6 0.0 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KFX94695.1 - 0.0022 17.7 0.5 0.84 9.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 KFX94695.1 - 0.0033 17.0 0.7 1.3 8.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFX94695.1 - 0.0035 17.6 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFX94695.1 - 0.0056 16.6 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX94695.1 - 0.0068 15.6 0.0 0.78 8.9 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 KFX94695.1 - 0.0071 15.8 0.1 2.6 7.5 0.1 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KFX94695.1 - 0.012 15.2 0.4 3.5 7.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KFX94695.1 - 0.031 13.9 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KFX94695.1 - 0.044 13.2 0.2 5.3 6.4 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KFX94695.1 - 0.1 12.7 0.3 18 5.5 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KFX94695.1 - 0.11 11.8 0.4 7.6 5.8 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Miro PF08477.8 KFX94695.1 - 0.24 11.9 0.0 8.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KFX94695.1 - 0.33 11.2 0.1 0.74 10.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KFX94695.1 - 0.79 8.6 0.0 4.2 6.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Glyco_hydro_3 PF00933.16 KFX94696.1 - 1.1e-53 182.2 0.0 2.3e-53 181.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_7 PF13508.1 KFX94696.1 - 0.0011 19.0 0.0 0.0034 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 KFX94696.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 KFX94696.1 - 0.0016 18.4 0.0 0.0055 16.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family NDT80_PhoG PF05224.7 KFX94697.1 - 2.1e-31 109.3 0.0 3.3e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Amidohydro_4 PF13147.1 KFX94698.1 - 8.2e-10 39.1 0.0 3.5e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX94698.1 - 2.8e-09 37.0 0.0 4.5e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX94698.1 - 6.8e-07 28.8 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFX94698.1 - 0.00013 21.7 0.0 0.00034 20.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase DUF3678 PF12435.3 KFX94698.1 - 2.5 7.7 8.6 5.4 6.6 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Abhydrolase_6 PF12697.2 KFX94699.1 - 1.5e-10 41.3 0.2 2.3e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MUG113 PF13455.1 KFX94700.1 - 6.6e-11 42.5 3.0 1.4e-10 41.4 1.5 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KFX94700.1 - 6.8e-11 42.4 0.5 1.4e-10 41.3 0.4 1.5 1 0 0 1 1 1 1 T5orf172 domain DUF2457 PF10446.4 KFX94700.1 - 0.02 13.6 16.6 0.033 12.9 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 KFX94700.1 - 0.07 11.6 7.3 0.093 11.2 5.1 1.3 1 0 0 1 1 1 0 Daxx Family DARPP-32 PF05395.7 KFX94700.1 - 0.34 11.0 8.1 0.61 10.2 3.7 2.4 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 SDA1 PF05285.7 KFX94700.1 - 2 7.5 15.0 3.6 6.7 10.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KFX94700.1 - 3.8 5.3 17.0 5 4.9 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KFX94700.1 - 7.6 4.4 9.1 10 4.0 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DAO PF01266.19 KFX94703.1 - 6.9e-50 169.9 0.3 1.4e-49 168.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_4 PF01565.18 KFX94703.1 - 5.8e-19 67.9 0.5 2.7e-18 65.7 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain Cellulase PF00150.13 KFX94703.1 - 3.2e-16 59.3 2.0 6.9e-16 58.2 1.4 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BBE PF08031.7 KFX94703.1 - 5.5e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_8 PF13450.1 KFX94703.1 - 1.3e-05 25.1 0.4 0.0024 17.8 0.1 3.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Cellulase-like PF12876.2 KFX94703.1 - 0.00033 21.0 0.0 0.00081 19.7 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KFX94703.1 - 0.0011 18.1 0.0 0.0034 16.5 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase Pyr_redox PF00070.22 KFX94703.1 - 0.0026 18.1 0.0 0.079 13.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX94703.1 - 0.013 14.3 1.1 0.034 12.9 0.7 1.7 1 1 0 1 1 1 0 FAD binding domain Mqo PF06039.10 KFX94703.1 - 0.028 12.5 0.1 0.77 7.8 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 KFX94703.1 - 0.028 14.2 1.7 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KFX94703.1 - 0.051 12.7 0.0 0.46 9.5 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 KFX94703.1 - 0.074 12.0 0.1 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_2_C PF02836.12 KFX94703.1 - 0.1 11.4 0.1 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain DUF1476 PF07345.6 KFX94706.1 - 0.047 13.9 5.6 0.23 11.7 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) tRNA-synt_2d PF01409.15 KFX94707.1 - 5.8e-47 159.9 0.9 3.3e-24 85.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GrpE PF01025.14 KFX94707.1 - 3e-44 150.4 4.7 5.7e-44 149.5 3.3 1.4 1 0 0 1 1 1 1 GrpE FDX-ACB PF03147.9 KFX94707.1 - 4.4e-26 90.8 0.0 1.2e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF2222 PF09984.4 KFX94707.1 - 0.08 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Mito_carr PF00153.22 KFX94708.1 - 9.5e-63 207.9 1.1 2.7e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.21 KFX94709.1 - 2.4e-32 111.3 0.0 4.3e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFX94709.1 - 2e-14 52.4 0.0 2.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.7 KFX94710.1 - 2.5e-48 164.1 0.3 3.1e-48 163.8 0.2 1.1 1 0 0 1 1 1 1 Calcipressin Mob1_phocein PF03637.12 KFX94711.1 - 1.8e-71 239.3 0.3 3.5e-71 238.4 0.0 1.5 2 0 0 2 2 2 1 Mob1/phocein family OSCP PF00213.13 KFX94711.1 - 4.3e-45 153.6 2.1 6.7e-45 153.0 1.4 1.3 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.12 KFX94711.1 - 0.043 13.6 0.5 0.089 12.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Rgp1 PF08737.5 KFX94712.1 - 5.3e-125 417.7 0.0 1.4e-124 416.3 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 KFX94712.1 - 0.034 13.9 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain CRM1_C PF08767.6 KFX94713.1 - 7.1e-132 439.1 1.5 3.3e-131 436.9 0.2 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 KFX94713.1 - 4.4e-38 130.4 3.7 4.4e-38 130.4 2.6 3.4 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 KFX94713.1 - 8.6e-12 44.8 0.2 4.4e-11 42.5 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 KFX94713.1 - 0.0059 16.8 0.2 7.5 6.8 0.2 3.7 3 0 0 3 3 3 1 Phosphohydrolase-associated domain DUF3385 PF11865.3 KFX94713.1 - 0.073 13.0 0.1 0.073 13.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) uDENN PF03456.13 KFX94713.1 - 0.1 12.5 0.6 3.4 7.7 0.1 3.0 3 0 0 3 3 3 0 uDENN domain Reprolysin_5 PF13688.1 KFX94714.1 - 1.9e-59 200.9 7.3 1.9e-59 200.9 5.0 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFX94714.1 - 1.3e-46 158.7 1.5 2.4e-46 157.8 1.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFX94714.1 - 7.8e-44 149.7 5.2 1.5e-43 148.8 2.7 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFX94714.1 - 1.3e-17 64.4 0.6 1.3e-17 64.4 0.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KFX94714.1 - 7.6e-17 61.3 29.1 7.6e-17 61.3 20.1 4.4 3 2 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 KFX94714.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide G_glu_transpept PF01019.16 KFX94715.1 - 4.9e-158 526.7 0.4 5.6e-158 526.5 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase IMS PF00817.15 KFX94716.1 - 6.8e-39 133.0 0.0 1e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFX94716.1 - 2.2e-10 40.5 0.1 3.9e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFX94716.1 - 0.01 15.8 0.0 0.035 14.1 0.0 2.0 1 0 0 1 1 1 0 IMS family HHH motif HHH_8 PF14716.1 KFX94716.1 - 0.033 14.3 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_5 PF14520.1 KFX94716.1 - 0.11 12.7 0.0 0.77 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Ribosomal_L3 PF00297.17 KFX94718.1 - 2.8e-119 397.3 7.4 3.4e-119 397.0 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PWI PF01480.12 KFX94720.1 - 1.7e-29 101.7 0.0 2.6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain GRP PF07172.6 KFX94720.1 - 0.074 13.5 1.5 0.13 12.7 1.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family DEAD PF00270.24 KFX94722.1 - 1.1e-20 73.7 0.1 3.2e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX94722.1 - 7e-18 64.2 0.0 5.4e-17 61.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 KFX94722.1 - 1.5e-14 53.6 1.6 2.1e-14 53.1 0.3 1.9 2 0 0 2 2 2 1 RQC domain HRDC PF00570.18 KFX94722.1 - 0.0034 17.0 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 HRDC domain Collar PF07484.7 KFX94723.1 - 0.094 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Collar Domain APH PF01636.18 KFX94724.1 - 0.00068 19.4 0.2 0.0017 18.1 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 KFX94725.1 - 4.2e-18 66.0 0.0 5.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94725.1 - 3.9e-07 29.9 0.0 9.7e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX94725.1 - 7.1e-06 25.7 0.0 2.4e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Trypan_PARP PF05887.6 KFX94727.1 - 0.043 13.6 1.1 0.056 13.2 0.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_tranf_2_3 PF13641.1 KFX94728.1 - 4.9e-15 55.9 0.0 6.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KFX94728.1 - 1.9e-07 30.9 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KFX94728.1 - 1.2e-06 27.9 0.0 2.4e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Abhydrolase_6 PF12697.2 KFX94729.1 - 1.3e-26 93.9 1.5 1.5e-26 93.7 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX94729.1 - 1.1e-16 61.0 0.0 2.2e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX94729.1 - 2.1e-09 37.2 0.0 4.1e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX94729.1 - 0.00047 19.5 0.1 0.049 12.8 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.15 KFX94729.1 - 0.005 16.2 0.0 0.008 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KFX94729.1 - 0.012 15.1 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 KFX94729.1 - 0.041 12.3 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.8 KFX94729.1 - 0.12 11.7 0.0 0.61 9.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 KFX94729.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 KFX94729.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 KFX94729.1 - 0.2 10.6 0.0 0.43 9.6 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Fungal_trans_2 PF11951.3 KFX94730.1 - 4.3e-17 61.7 0.4 6.6e-17 61.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Drf_FH1 PF06346.7 KFX94730.1 - 0.0036 16.8 3.5 0.0062 16.0 2.5 1.2 1 0 0 1 1 1 1 Formin Homology Region 1 Sugar_tr PF00083.19 KFX94731.1 - 3.1e-69 233.7 18.2 5.2e-42 143.9 1.6 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFX94731.1 - 1.3e-15 56.9 18.9 1.3e-15 56.9 13.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX94731.1 - 0.0032 15.9 0.5 0.0032 15.9 0.3 2.9 2 2 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 KFX94731.1 - 0.004 15.9 1.2 0.0047 15.6 0.2 1.5 2 0 0 2 2 2 1 PUCC protein Ank_2 PF12796.2 KFX94732.1 - 9e-29 99.6 9.9 2.7e-15 56.4 0.6 3.2 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94732.1 - 2e-26 90.4 11.2 5.1e-06 26.0 0.1 6.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFX94732.1 - 8.2e-20 70.3 9.6 1.3e-07 31.5 0.3 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94732.1 - 2.6e-19 67.3 3.8 0.00025 20.9 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFX94732.1 - 1.2e-18 67.1 11.7 1.1e-08 35.3 0.3 6.8 5 2 3 8 8 7 5 Ankyrin repeats (many copies) TPR_12 PF13424.1 KFX94732.1 - 8.1e-07 28.8 0.2 1.1e-05 25.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX94732.1 - 0.0014 18.2 0.0 0.04 13.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX94732.1 - 0.004 17.4 4.3 0.23 11.8 0.5 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX94732.1 - 0.008 15.7 0.7 0.027 14.1 0.5 1.9 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 KFX94732.1 - 0.051 14.2 0.7 0.25 12.0 0.0 2.5 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFX94732.1 - 0.055 13.4 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat tRNA_anti-codon PF01336.20 KFX94732.1 - 0.095 12.5 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain TPR_8 PF13181.1 KFX94732.1 - 1.3 8.9 9.5 0.085 12.6 0.4 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX94732.1 - 2 8.5 8.3 0.075 12.9 0.9 2.5 3 0 0 3 3 1 0 Tetratricopeptide repeat MFS_1 PF07690.11 KFX94733.1 - 6.9e-42 143.4 70.9 8.7e-39 133.2 41.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.19 KFX94735.1 - 4.4e-16 58.9 0.4 1.5e-15 57.2 0.3 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFX94735.1 - 2.2e-09 37.2 0.2 5.3e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX94735.1 - 1.7e-05 23.8 0.1 0.00076 18.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFX94735.1 - 0.0002 20.5 0.3 0.00069 18.8 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX94735.1 - 0.011 16.0 1.5 0.38 11.1 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX94735.1 - 0.055 11.9 0.6 0.11 10.9 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 KFX94735.1 - 0.11 11.0 0.2 0.16 10.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PUF PF00806.14 KFX94742.1 - 1.6e-31 105.9 8.1 1.6e-08 33.5 0.1 4.8 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Repressor_Mnt PF11423.3 KFX94742.1 - 0.05 12.9 0.4 0.11 11.7 0.3 1.5 1 0 0 1 1 1 0 Regulatory protein Mnt Catalase PF00199.14 KFX94744.1 - 1.7e-24 86.2 0.4 2.2e-24 85.8 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFX94744.1 - 2.3e-12 46.5 0.0 3.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Catalase-related immune-responsive 2H-phosphodiest PF08975.5 KFX94745.1 - 2.5e-12 46.5 0.0 3.2e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1868) LigT_PEase PF02834.11 KFX94745.1 - 0.0002 21.2 0.1 0.00052 19.9 0.0 1.7 2 0 0 2 2 2 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 KFX94745.1 - 0.0033 17.1 0.1 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily HVSL PF09749.4 KFX94745.1 - 0.036 13.0 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF3430 PF11912.3 KFX94746.1 - 0.072 12.9 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) DUF3659 PF12396.3 KFX94747.1 - 1.5e-118 386.5 60.4 8.4e-24 83.0 5.3 6.6 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) GCK PF07802.6 KFX94747.1 - 0.029 14.4 0.4 0.063 13.4 0.2 1.5 1 0 0 1 1 1 0 GCK domain DUF842 PF05811.8 KFX94747.1 - 0.091 12.2 0.6 0.22 10.9 0.4 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) CorA PF01544.13 KFX94747.1 - 0.21 10.5 0.0 0.73 8.8 0.2 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Lin-8 PF03353.10 KFX94750.1 - 2.8 7.1 10.3 3 7.0 7.2 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.7 KFX94750.1 - 3.1 6.2 6.6 3.5 6.1 4.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF605 PF04652.11 KFX94750.1 - 3.7 6.8 12.7 4.1 6.7 8.8 1.0 1 0 0 1 1 1 0 Vta1 like POP1 PF06978.6 KFX94752.1 - 1e-59 201.3 6.6 1e-59 201.3 4.6 1.6 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KFX94752.1 - 5.6e-29 99.8 0.3 1.5e-28 98.4 0.2 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain SLD3 PF08639.5 KFX94752.1 - 0.13 10.8 5.5 0.21 10.1 3.8 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Adeno_terminal PF02459.10 KFX94752.1 - 0.37 8.8 5.7 0.53 8.3 4.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Redoxin PF08534.5 KFX94753.1 - 1.3e-34 118.8 0.1 1.5e-34 118.6 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFX94753.1 - 5.6e-14 51.8 0.0 6.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 KFX94754.1 - 2.8e-57 192.5 3.6 3.4e-57 192.2 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 KFX94754.1 - 2.9e-08 34.0 1.3 4.1e-08 33.5 0.9 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFX94754.1 - 8.5e-06 25.9 0.1 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4398 PF14346.1 KFX94754.1 - 0.045 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Y_phosphatase3 PF13350.1 KFX94755.1 - 2.9e-43 147.9 0.0 4.7e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFX94755.1 - 8.6e-08 32.1 0.0 1.9e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KFX94755.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFX94755.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KFX94755.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Glyco_hydro_3 PF00933.16 KFX94756.1 - 2.2e-91 305.9 0.0 3.1e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX94756.1 - 2.6e-57 193.9 0.4 1.4e-56 191.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX94756.1 - 3.7e-21 74.8 0.0 8.3e-21 73.7 0.0 1.6 1 1 0 1 1 1 1 Fibronectin type III-like domain PIRT PF15099.1 KFX94756.1 - 0.21 10.8 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Dala_Dala_lig_C PF07478.8 KFX94757.1 - 5.2e-28 97.8 0.0 7.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 KFX94757.1 - 5.7e-09 35.9 0.0 9.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFX94757.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFX94757.1 - 0.00032 20.0 0.0 0.0012 18.1 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 KFX94757.1 - 0.00071 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 KFX94757.1 - 0.0043 15.8 0.0 0.11 11.2 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_N PF01820.16 KFX94757.1 - 0.009 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus Glyco_hydro_16 PF00722.16 KFX94758.1 - 3.1e-09 36.3 1.7 6e-09 35.4 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2235 PF09994.4 KFX94759.1 - 2.2e-76 256.8 0.1 3.3e-76 256.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KFX94759.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 KFX94759.1 - 0.038 13.7 0.0 0.085 12.5 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Mei5 PF10376.4 KFX94759.1 - 2.7 7.4 8.9 0.8 9.1 2.8 2.1 2 0 0 2 2 2 0 Double-strand recombination repair protein An_peroxidase PF03098.10 KFX94760.1 - 6.4e-77 259.1 0.0 1.2e-74 251.6 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KFX94760.1 - 4.9e-10 38.5 0.1 2.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cellulase PF00150.13 KFX94762.1 - 3.3e-56 190.5 0.1 4.2e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cytomega_UL20A PF05984.7 KFX94762.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein RGS PF00615.14 KFX94763.1 - 5.3e-09 36.1 0.0 4e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain MPC PF03650.8 KFX94764.1 - 1.6e-41 141.0 0.6 2.1e-41 140.6 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 KFX94765.1 - 5.4e-13 48.4 0.0 6.8e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ribosomal_60s PF00428.14 KFX94767.1 - 2.7 8.4 10.2 1.1 9.7 2.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABA_GPCR PF12430.3 KFX94768.1 - 1.6e-50 170.9 0.0 3.4e-50 169.9 0.0 1.5 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KFX94768.1 - 2.4e-19 69.1 0.1 6.2e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Usp PF00582.21 KFX94769.1 - 3.2e-15 56.5 0.0 7.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family SseC PF04888.7 KFX94769.1 - 0.011 15.0 0.5 0.023 14.0 0.4 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Flu_B_M2 PF04772.7 KFX94769.1 - 0.15 12.0 0.3 0.42 10.6 0.2 1.8 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Paf67 PF10255.4 KFX94770.1 - 2.2e-154 514.2 0.6 2.6e-154 513.9 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KFX94770.1 - 0.02 14.8 0.2 0.13 12.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ku PF02735.11 KFX94772.1 - 2.6e-24 85.7 0.0 5.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KFX94772.1 - 1.5e-21 76.8 0.0 2.4e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KFX94772.1 - 1.2e-11 44.5 0.0 2.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 KFX94772.1 - 1.5e-05 25.1 0.3 3.5e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX94772.1 - 0.012 15.3 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Curto_V2 PF07325.6 KFX94772.1 - 0.022 14.4 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Curtovirus V2 protein DUF4149 PF13664.1 KFX94773.1 - 7.6e-24 83.7 2.7 7.6e-24 83.7 1.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MatE PF01554.13 KFX94774.1 - 2.5e-50 170.2 25.1 4.8e-31 107.5 4.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KFX94774.1 - 9.7e-05 22.1 7.0 9.7e-05 22.1 4.9 4.2 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PSI_PSAK PF01241.13 KFX94774.1 - 0.026 14.5 1.2 0.3 11.1 0.1 2.6 1 1 1 2 2 2 0 Photosystem I psaG / psaK SnoaL PF07366.7 KFX94775.1 - 9.4e-25 86.6 0.0 1.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KFX94775.1 - 5.3e-12 46.0 0.0 8.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Stb3 PF10330.4 KFX94776.1 - 5.3e-38 128.6 0.0 8.5e-38 127.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein NUC129 PF08157.6 KFX94777.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 NUC129 domain Topoisom_bac PF01131.15 KFX94778.1 - 1.4e-89 300.7 0.0 1.7e-84 283.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 KFX94778.1 - 1.2e-17 63.6 0.0 2.9e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF2320 PF10082.4 KFX94778.1 - 0.1 11.2 0.1 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2320) API5 PF05918.6 KFX94778.1 - 0.53 8.7 3.7 0.78 8.1 2.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1295 PF06966.7 KFX94779.1 - 3.8e-34 118.0 7.4 4.8e-34 117.6 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DPM2 PF07297.7 KFX94782.1 - 2.6e-34 117.3 2.1 4.7e-34 116.5 1.5 1.4 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KFX94782.1 - 0.00038 20.0 2.0 0.00058 19.4 1.4 1.3 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KFX94782.1 - 0.0069 16.2 1.1 0.0069 16.2 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 KFX94782.1 - 0.016 14.9 0.2 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Cytochrom_C_asm PF01578.15 KFX94782.1 - 0.037 13.5 0.8 0.044 13.3 0.6 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein MA3 PF02847.12 KFX94783.1 - 5.6e-26 90.4 0.0 2.7e-25 88.2 0.0 2.1 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KFX94783.1 - 7.7e-26 90.7 0.8 1.8e-25 89.5 0.3 1.8 2 0 0 2 2 2 1 MIF4G domain FAM176 PF14851.1 KFX94783.1 - 0.56 9.8 4.5 1.5 8.5 3.1 1.7 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 KFX94783.1 - 4.5 7.5 13.9 0.32 11.2 4.1 2.7 2 1 0 2 2 2 0 Centromere protein B dimerisation domain Sec34 PF04136.10 KFX94785.1 - 0.035 13.8 1.7 3.3 7.4 0.5 2.5 2 1 0 2 2 2 0 Sec34-like family Spectrin PF00435.16 KFX94785.1 - 0.47 10.7 6.7 23 5.3 3.1 2.7 2 0 0 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 KFX94785.1 - 2 8.0 11.6 0.22 11.1 3.9 2.1 1 1 1 2 2 2 0 Mnd1 family Tropomyosin_1 PF12718.2 KFX94785.1 - 5.5 6.8 15.3 7.7 6.3 8.5 2.2 2 0 0 2 2 2 0 Tropomyosin like Glyco_hydro_72 PF03198.9 KFX94793.1 - 1.7e-111 372.2 0.1 2.1e-111 371.9 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KFX94793.1 - 0.00015 20.8 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KFX94793.1 - 0.072 12.2 0.3 3.1 6.9 0.2 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) ATP-grasp_2 PF08442.5 KFX94794.1 - 1e-06 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.14 KFX94795.1 - 2.1e-18 66.5 0.0 7.4e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 KFX94795.1 - 1.4e-17 63.5 0.0 3.5e-15 55.5 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 KFX94795.1 - 1.9e-13 50.2 0.1 3.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFX94795.1 - 0.00015 21.3 0.0 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L18e PF00828.14 KFX94797.1 - 1.1e-14 54.8 0.1 1.1e-14 54.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 KFX94798.1 - 5.3e-75 247.2 5.4 1.2e-25 89.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 KFX94799.1 - 6.4e-12 44.9 0.0 9e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX94799.1 - 6e-08 32.5 0.0 9.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX94799.1 - 1.2e-07 31.4 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX94799.1 - 0.0038 16.9 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CH PF00307.26 KFX94800.1 - 3.4e-63 210.4 0.0 2.2e-19 69.4 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFX94800.1 - 1.1e-06 28.7 0.2 0.00011 22.2 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFX94800.1 - 0.00022 20.2 2.0 0.16 11.3 0.3 3.5 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 KFX94800.1 - 0.0068 16.0 0.0 16 5.2 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.1 KFX94800.1 - 0.011 15.5 4.2 0.081 12.8 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.1 KFX94800.1 - 0.22 10.9 3.4 0.51 9.7 0.3 2.9 2 0 0 2 2 2 0 EF hand DWNN PF08783.6 KFX94801.1 - 1.4e-30 105.0 0.1 2.3e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KFX94801.1 - 0.00013 21.3 2.5 0.00039 19.8 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFX94801.1 - 0.00087 19.1 1.3 0.0017 18.1 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 KFX94801.1 - 0.0022 17.8 0.1 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KFX94801.1 - 0.035 13.6 5.0 0.079 12.4 3.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 KFX94801.1 - 0.066 12.6 1.3 0.21 11.1 0.9 1.8 1 1 0 1 1 1 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 KFX94801.1 - 0.15 11.9 1.3 0.26 11.0 0.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFX94801.1 - 0.15 11.7 5.5 0.3 10.6 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFX94801.1 - 0.37 10.7 9.7 1.2 9.0 6.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFX94801.1 - 0.54 9.9 9.2 1.1 8.9 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX94801.1 - 0.93 9.5 14.6 0.095 12.7 5.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX94801.1 - 1.6 8.4 11.6 0.16 11.7 4.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.16 KFX94802.1 - 8.1e-46 156.1 1.0 4.1e-45 153.8 0.7 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KFX94802.1 - 5.9e-28 97.6 0.0 9.8e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KFX94802.1 - 1.9e-11 43.9 0.0 4.1e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KFX94802.1 - 2.1e-08 33.8 0.0 3.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KFX94802.1 - 0.0023 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KFX94802.1 - 0.0061 16.0 0.2 0.21 11.0 0.0 2.3 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 KFX94802.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 dCMP_cyt_deam_1 PF00383.17 KFX94803.1 - 1e-27 95.7 1.1 1.8e-27 94.9 0.7 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KFX94803.1 - 1e-05 26.3 0.0 1.7e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX94803.1 - 0.00019 21.7 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KFX94803.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase DUF1338 PF07063.8 KFX94803.1 - 0.12 11.4 0.2 0.59 9.1 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1338) ThiF PF00899.16 KFX94804.1 - 2.8e-28 98.4 0.0 4.7e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFX94804.1 - 0.00081 19.5 0.0 0.007 16.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Toprim PF01751.17 KFX94804.1 - 0.0035 17.2 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 1 Toprim domain 2-Hacid_dh_C PF02826.14 KFX94804.1 - 0.16 11.1 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MIT PF04212.13 KFX94805.1 - 2.5e-10 40.1 0.4 5.6e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PXA PF02194.10 KFX94806.1 - 2.9e-30 105.1 0.2 1.4e-29 103.0 0.0 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFX94806.1 - 5e-21 74.9 0.2 1.6e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 KFX94806.1 - 1.5e-08 34.4 0.0 9.6e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 PX domain PC4 PF02229.11 KFX94807.1 - 2.5e-18 65.0 0.0 4.1e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DDHD PF02862.12 KFX94808.1 - 3.9e-74 249.2 1.3 1.6e-73 247.3 0.0 2.5 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.9 KFX94808.1 - 0.13 11.5 0.2 0.95 8.7 0.0 2.4 3 0 0 3 3 3 0 Putative serine esterase (DUF676) LCAT PF02450.10 KFX94808.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ku PF02735.11 KFX94811.1 - 1.6e-41 141.9 0.0 3.2e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KFX94811.1 - 1.2e-34 119.6 0.0 1.7e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KFX94811.1 - 1e-10 40.8 0.0 2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 KFX94811.1 - 5.3e-08 33.2 1.5 7.5e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 KFX94811.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain PAT1 PF09770.4 KFX94821.1 - 5.1 5.2 14.7 8.1 4.5 10.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HsbA PF12296.3 KFX94822.1 - 6.9e-26 90.5 9.3 1e-25 90.0 6.5 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.7 KFX94822.1 - 0.0023 17.7 4.9 0.064 13.0 1.2 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M75 PF09375.5 KFX94822.1 - 0.15 11.3 4.7 1.2 8.3 3.2 1.9 1 1 0 1 1 1 0 Imelysin NPV_P10 PF05531.7 KFX94822.1 - 1.3 9.3 4.5 4.7 7.5 0.1 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAT PF03417.11 KFX94823.1 - 1.3e-19 70.5 0.0 8.6e-18 64.6 0.0 2.8 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KFX94823.1 - 1.7e-05 25.0 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TRAPP PF04051.11 KFX94824.1 - 1.8e-37 128.1 0.1 2.1e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 KFX94825.1 - 1.5e-56 186.3 6.2 3.3e-10 39.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFX94825.1 - 0.00078 18.2 0.4 0.094 11.4 0.1 2.2 1 1 0 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.1 KFX94825.1 - 0.11 12.2 0.0 0.71 9.6 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ChW PF07538.6 KFX94829.1 - 0.13 11.7 0.3 0.8 9.2 0.0 2.0 2 0 0 2 2 2 0 Clostridial hydrophobic W Abhydrolase_3 PF07859.8 KFX94834.1 - 1.1e-34 119.8 0.0 6.6e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KFX94834.1 - 2.1e-07 30.0 0.0 4.2e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFX94834.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX94834.1 - 0.067 12.6 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RICTOR_M PF14666.1 KFX94834.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DUF2974 PF11187.3 KFX94834.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Mito_carr PF00153.22 KFX94836.1 - 6.8e-60 198.8 4.9 1.9e-20 72.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KFX94837.1 - 8e-18 63.5 0.1 5e-11 42.0 0.2 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4613 PF15390.1 KFX94837.1 - 0.0068 14.6 0.0 0.01 14.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) COX5B PF01215.14 KFX94843.1 - 1.5e-36 125.0 0.0 1.9e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.5 KFX94843.1 - 0.053 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc ribbon domain RRN7 PF11781.3 KFX94843.1 - 0.092 12.2 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 ADK_lid PF05191.9 KFX94843.1 - 0.17 11.5 2.2 0.31 10.7 1.6 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA PF00004.24 KFX94844.1 - 4e-97 321.4 0.0 2.1e-47 160.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFX94844.1 - 5.9e-20 71.0 0.3 1.8e-19 69.4 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.1 KFX94844.1 - 1.1e-13 51.3 0.0 2.6e-06 27.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 KFX94844.1 - 1.3e-13 51.2 0.0 2.3e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFX94844.1 - 5.6e-13 48.4 0.0 2.3e-05 23.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFX94844.1 - 6.8e-12 45.3 0.6 4.1e-06 26.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFX94844.1 - 1.4e-11 45.2 0.0 0.00039 21.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFX94844.1 - 2.3e-11 43.9 0.2 0.0022 18.1 0.0 4.4 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KFX94844.1 - 3.7e-10 40.1 0.6 0.0011 18.9 0.0 3.8 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 KFX94844.1 - 3.9e-09 35.7 0.0 0.0013 17.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KFX94844.1 - 1e-07 31.5 0.0 0.012 15.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KFX94844.1 - 1.2e-07 31.6 0.0 0.0061 16.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 KFX94844.1 - 2.5e-07 30.2 0.0 6.6e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 KFX94844.1 - 3.3e-07 29.5 0.0 0.0049 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KFX94844.1 - 4.6e-07 29.2 0.2 0.031 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFX94844.1 - 4.7e-07 29.4 1.9 0.014 15.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 KFX94844.1 - 5.5e-07 29.1 5.1 0.073 12.4 0.0 4.4 2 2 1 4 4 4 2 AAA domain RNA_helicase PF00910.17 KFX94844.1 - 2.5e-06 27.6 0.0 0.034 14.3 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 KFX94844.1 - 2.7e-06 26.6 0.7 0.52 9.3 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 KFX94844.1 - 4.5e-06 26.9 0.0 0.048 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KFX94844.1 - 1.3e-05 25.1 0.0 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KFX94844.1 - 1.5e-05 25.0 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 KFX94844.1 - 1.7e-05 23.8 0.0 0.012 14.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KFX94844.1 - 3e-05 23.7 0.0 0.13 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 KFX94844.1 - 3e-05 23.5 0.0 0.29 10.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFX94844.1 - 3.2e-05 23.9 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 KFX94844.1 - 3.7e-05 23.0 0.2 0.31 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 KFX94844.1 - 5.7e-05 23.4 0.0 0.28 11.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 KFX94844.1 - 7.1e-05 21.8 0.0 0.068 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KFX94844.1 - 8.7e-05 22.3 0.0 5.5 6.6 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase AAA_3 PF07726.6 KFX94844.1 - 0.00041 19.9 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KFX94844.1 - 0.00058 19.4 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 KFX94844.1 - 0.00066 19.3 0.0 1.9 8.0 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.1 KFX94844.1 - 0.00067 19.2 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 KFX94844.1 - 0.00072 19.3 0.1 0.003 17.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NACHT PF05729.7 KFX94844.1 - 0.0011 18.6 0.0 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 KFX94844.1 - 0.0012 17.8 0.0 0.5 9.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KFX94844.1 - 0.0022 17.7 0.8 1 9.0 0.0 4.2 4 0 0 4 4 4 1 NTPase NB-ARC PF00931.17 KFX94844.1 - 0.0031 16.4 0.1 0.57 8.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 KFX94844.1 - 0.01 15.4 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 KFX94844.1 - 0.013 14.6 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 KFX94844.1 - 0.018 14.0 0.0 1 8.2 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain AAA_10 PF12846.2 KFX94844.1 - 0.042 13.2 0.7 10 5.4 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 KFX94844.1 - 0.044 13.6 0.1 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KFX94844.1 - 0.062 12.4 0.2 19 4.3 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MobB PF03205.9 KFX94844.1 - 0.09 12.4 0.2 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KFX94844.1 - 0.13 11.8 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 KFX94844.1 - 0.19 11.1 0.3 31 3.9 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) zf-C2H2 PF00096.21 KFX94847.1 - 5.9e-09 35.7 11.9 2.6e-05 24.2 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KFX94847.1 - 4.6e-06 25.6 0.0 6.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_6 PF13912.1 KFX94847.1 - 7.2e-05 22.5 8.9 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFX94847.1 - 9.1e-05 22.5 10.9 0.034 14.4 3.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX94847.1 - 0.00012 22.2 3.6 0.00012 22.2 2.5 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFX94847.1 - 0.00057 19.9 1.1 0.23 11.6 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX94847.1 - 0.083 13.1 0.8 17 5.7 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.17 KFX94847.1 - 0.18 11.9 2.5 0.45 10.6 1.7 1.7 1 1 0 1 1 1 0 LIM domain zf-BED PF02892.10 KFX94847.1 - 0.53 10.0 7.1 0.59 9.9 4.0 1.8 2 0 0 2 2 2 0 BED zinc finger MFS_1 PF07690.11 KFX94848.1 - 4.1e-40 137.5 21.2 4.1e-40 137.5 14.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX94848.1 - 4.8e-10 38.5 29.0 3.2e-08 32.5 20.1 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFX94848.1 - 2.3e-08 32.7 6.3 1.9e-07 29.6 1.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFX94848.1 - 0.0012 17.3 5.7 0.0012 17.3 4.0 2.7 2 1 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 KFX94848.1 - 0.0025 16.5 2.3 0.064 11.9 0.5 2.4 2 0 0 2 2 2 2 PUCC protein MFS_1_like PF12832.2 KFX94848.1 - 0.0056 16.4 1.4 0.39 10.5 0.0 3.6 3 1 0 3 3 3 1 MFS_1 like family FAD_binding_3 PF01494.14 KFX94849.1 - 2.8e-20 72.7 0.1 2.8e-12 46.3 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX94849.1 - 2.9e-08 33.6 0.4 7e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX94849.1 - 0.00095 18.1 2.7 0.0023 16.8 1.7 1.6 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX94849.1 - 0.0011 18.9 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX94849.1 - 0.0025 17.9 0.2 0.0036 17.3 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX94849.1 - 0.0027 16.6 0.6 0.0027 16.6 0.4 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFX94849.1 - 0.0029 16.7 0.3 0.0047 16.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KFX94849.1 - 0.0044 17.4 0.2 0.02 15.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX94849.1 - 0.0063 16.3 0.2 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.9 KFX94849.1 - 0.0076 14.9 0.2 0.014 14.0 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 KFX94849.1 - 0.052 13.2 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KFX94849.1 - 0.067 12.5 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 KFX94849.1 - 0.08 11.7 2.2 0.064 12.1 0.6 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KFX94849.1 - 0.1 11.0 0.4 0.16 10.4 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 KFX94849.1 - 0.12 12.4 0.3 0.32 11.1 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFX94849.1 - 0.17 11.6 0.7 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 KFX94849.1 - 2.2 8.7 4.5 0.63 10.5 0.5 2.1 2 1 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3500 PF12006.3 KFX94850.1 - 1e-88 297.3 0.0 1.2e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) SSP160 PF06933.6 KFX94851.1 - 0.0062 14.5 5.8 0.0086 14.1 4.0 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1628 PF07790.6 KFX94851.1 - 0.012 16.3 0.7 0.025 15.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Shisa PF13908.1 KFX94851.1 - 0.027 14.6 0.9 0.039 14.1 0.4 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PAN_1 PF00024.21 KFX94851.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 PAN domain PilX_N PF14341.1 KFX94851.1 - 0.057 13.0 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 PilX N-terminal PAN_4 PF14295.1 KFX94851.1 - 0.059 13.0 0.6 0.31 10.7 0.4 2.1 1 1 0 1 1 1 0 PAN domain Med3 PF11593.3 KFX94851.1 - 5.2 6.1 6.8 6.4 5.9 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_C15 PF01470.12 KFX94852.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Pyroglutamyl peptidase Gp-FAR-1 PF05823.7 KFX94852.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FAA_hydrolase PF01557.13 KFX94853.1 - 2.8e-52 177.3 0.0 8.8e-52 175.6 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family Cyanate_lyase PF02560.9 KFX94854.1 - 1.2e-30 104.7 0.0 1.7e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 KFX94854.1 - 0.00062 19.1 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.17 KFX94854.1 - 0.0038 17.0 0.1 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix DUF3786 PF12654.2 KFX94854.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) HTH_31 PF13560.1 KFX94854.1 - 0.066 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Arm PF00514.18 KFX94855.1 - 8.2e-93 301.4 15.7 2.8e-13 49.1 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFX94855.1 - 3.8e-30 104.0 2.5 1.5e-09 37.9 0.0 6.2 2 1 7 9 9 9 7 HEAT repeats IBB PF01749.15 KFX94855.1 - 8.2e-23 80.3 2.1 1.6e-22 79.4 1.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFX94855.1 - 1.4e-20 73.1 12.0 6.9e-09 35.9 0.1 6.3 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KFX94855.1 - 7.1e-19 66.1 3.8 2.9e-05 23.7 0.0 7.1 8 0 0 8 8 7 4 HEAT repeat Arm_2 PF04826.8 KFX94855.1 - 5.9e-10 38.6 0.0 0.0032 16.6 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KFX94855.1 - 1.8e-05 23.2 0.0 0.0025 16.2 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KFX94855.1 - 0.00017 21.5 0.1 1.7 8.6 0.0 4.5 2 1 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFX94855.1 - 0.0021 16.4 0.1 0.3 9.3 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KFX94855.1 - 0.0056 17.0 3.1 1.6 9.4 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.6 KFX94855.1 - 0.11 11.5 0.0 1.1 8.1 0.0 2.4 2 1 0 2 2 2 0 Mo25-like POT1 PF02765.12 KFX94856.1 - 8.8e-07 28.9 0.0 4.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DUF3328 PF11807.3 KFX94862.1 - 2.6e-29 102.4 0.0 3.4e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Collagen PF01391.13 KFX94864.1 - 0.011 15.2 10.3 0.023 14.2 7.1 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Zn_clus PF00172.13 KFX94865.1 - 0.2 11.5 24.6 0.54 10.2 4.1 3.9 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.5 KFX94865.1 - 0.86 9.8 10.1 0.1 12.8 0.8 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sedlin_N PF04628.8 KFX94866.1 - 8.2e-19 67.7 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Nucleoporin_N PF08801.6 KFX94867.1 - 6.4e-75 252.4 0.0 8.8e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 KFX94867.1 - 4.3e-66 223.6 2.1 5.5e-66 223.3 1.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal OPA3 PF07047.7 KFX94867.1 - 0.42 10.3 4.6 0.18 11.6 1.2 1.8 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) BMF PF15185.1 KFX94878.1 - 0.0076 15.5 4.4 0.014 14.7 3.0 1.4 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis Ribosomal_60s PF00428.14 KFX94878.1 - 0.017 15.4 11.0 0.052 13.9 7.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.6 KFX94878.1 - 0.03 13.5 9.4 0.054 12.7 6.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 KFX94878.1 - 1.5 8.3 10.8 0.034 13.6 2.7 1.6 2 0 0 2 2 2 0 Nucleoplasmin AA_permease PF00324.16 KFX94881.1 - 4.8e-123 411.0 43.8 5.7e-123 410.7 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX94881.1 - 1.6e-28 99.3 49.1 2.2e-28 98.9 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease LSM PF01423.17 KFX94882.1 - 8.3e-15 54.0 0.3 1.1e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain NigD PF12667.2 KFX94884.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 NigD-like protein DUF1399 PF07173.7 KFX94885.1 - 3.7e-20 72.6 3.0 1.5e-17 64.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) NUDIX PF00293.23 KFX94885.1 - 1.1e-07 31.5 0.0 2.4e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain Peptidase_S32 PF05579.8 KFX94885.1 - 0.0068 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Sugar_tr PF00083.19 KFX94887.1 - 1.4e-33 116.2 34.6 1.8e-20 72.9 11.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFX94887.1 - 9e-19 67.3 42.1 2e-09 36.6 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KFX94887.1 - 0.021 13.3 20.5 0.19 10.1 1.6 2.5 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Cation_efflux PF01545.16 KFX94887.1 - 0.18 10.8 5.5 0.72 8.8 0.1 2.8 2 1 0 2 2 2 0 Cation efflux family DUF1228 PF06779.9 KFX94887.1 - 3 7.9 10.3 0.084 12.9 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) CTP_transf_2 PF01467.21 KFX94888.1 - 2e-26 92.9 0.0 2.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase ABC2_membrane PF01061.19 KFX94890.1 - 1.7e-92 308.3 55.0 3.2e-50 170.2 15.9 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KFX94890.1 - 4.1e-37 125.9 0.1 3.7e-29 100.3 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KFX94890.1 - 4.1e-36 124.2 0.0 2e-17 63.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KFX94890.1 - 2.2e-23 82.1 0.0 5.1e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFX94890.1 - 4.3e-07 29.5 0.2 7.3e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KFX94890.1 - 1.4e-05 24.3 0.1 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KFX94890.1 - 1.8e-05 23.9 9.5 1.8e-05 23.9 6.6 3.7 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.1 KFX94890.1 - 0.00011 22.1 5.1 0.00061 19.8 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KFX94890.1 - 0.00012 21.9 0.1 0.014 15.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFX94890.1 - 0.0002 20.7 0.8 0.032 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KFX94890.1 - 0.0012 18.8 0.2 1.7 8.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFX94890.1 - 0.0051 16.9 0.1 1.4 9.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX94890.1 - 0.0078 15.4 0.0 0.46 9.6 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KFX94890.1 - 0.011 15.1 2.0 0.14 11.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFX94890.1 - 0.012 15.3 1.3 1.9 8.3 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KFX94890.1 - 0.016 16.0 0.0 0.88 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFX94890.1 - 0.018 15.3 0.1 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Peptidase_M50 PF02163.17 KFX94890.1 - 0.045 12.7 4.7 3.2 6.6 1.8 3.3 4 1 0 4 4 4 0 Peptidase family M50 NACHT PF05729.7 KFX94890.1 - 0.069 12.8 1.9 2.2 7.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 KFX94890.1 - 0.14 12.0 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KFX94890.1 - 0.3 10.7 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DASH_Spc19 PF08287.6 KFX94892.1 - 9.8e-25 86.9 0.0 1.6e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 KFX94892.1 - 0.0025 17.9 0.0 0.0049 16.9 0.0 1.4 2 0 0 2 2 2 1 Mur ligase middle domain Viral_P18 PF04521.8 KFX94892.1 - 0.094 12.1 4.6 0.27 10.6 0.3 2.1 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2968 PF11180.3 KFX94896.1 - 0.018 14.4 22.8 0.007 15.7 6.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) SepZ PF06066.6 KFX94896.1 - 0.023 14.6 1.6 0.03 14.3 0.1 1.8 2 0 0 2 2 2 0 SepZ FdtA PF05523.6 KFX94896.1 - 0.37 10.2 0.0 0.71 9.3 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal V_ATPase_I PF01496.14 KFX94896.1 - 0.38 8.5 6.3 0.68 7.7 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2450 PF10475.4 KFX94896.1 - 0.65 8.8 2.4 1.2 7.9 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF2576 PF10845.3 KFX94896.1 - 0.93 8.7 1.0 2.8 7.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) KxDL PF10241.4 KFX94896.1 - 4 7.4 10.3 0.66 9.9 1.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein PGPGW PF09656.5 KFX94897.1 - 0.12 11.7 0.6 0.26 10.5 0.4 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Sugar_tr PF00083.19 KFX94900.1 - 1.3e-67 228.3 30.6 1.5e-67 228.1 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94900.1 - 5.3e-14 51.6 30.7 5.3e-14 51.6 21.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1961 PF09224.6 KFX94901.1 - 6.2e-83 277.1 0.0 7.7e-83 276.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) Ammonium_transp PF00909.16 KFX94902.1 - 1.5e-109 366.0 30.8 1.8e-109 365.8 21.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CRT10 PF08728.5 KFX94904.1 - 9.1e-07 27.2 0.0 1.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 CRT10 Nucleoplasmin PF03066.10 KFX94904.1 - 0.75 9.3 4.0 1.2 8.5 2.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin TGS PF02824.16 KFX94907.1 - 8.9e-22 76.6 0.1 2e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFX94907.1 - 3.3e-19 68.9 0.1 8.7e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX94907.1 - 7.5e-10 38.3 0.0 4.1e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFX94907.1 - 0.0002 20.8 2.2 1.4 8.3 0.0 4.2 3 2 1 4 4 4 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFX94907.1 - 0.00026 20.8 0.1 0.054 13.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KFX94907.1 - 0.0019 18.6 0.0 0.0068 16.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KFX94907.1 - 0.0072 15.1 0.1 0.017 13.9 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Arf PF00025.16 KFX94907.1 - 0.039 13.1 0.2 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Steroid_dh PF02544.11 KFX94908.1 - 1.4e-10 41.1 0.4 6.3e-10 39.0 0.0 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFX94908.1 - 0.01 15.1 0.4 0.018 14.3 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) 2OG-FeII_Oxy_2 PF13532.1 KFX94909.1 - 1.5e-13 51.0 0.0 2e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFX94909.1 - 2.5e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 KFX94910.1 - 4.4e-25 87.8 0.3 2e-18 66.5 0.1 2.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94910.1 - 4.3e-21 73.6 4.2 1.1e-07 31.3 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFX94910.1 - 1.9e-20 72.4 3.1 1.3e-07 31.6 0.2 5.4 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX94910.1 - 9.7e-18 64.1 0.1 4.4e-07 30.2 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94910.1 - 1e-14 53.1 0.6 0.00014 21.7 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat AMP-binding PF00501.23 KFX94920.1 - 1.9e-37 128.6 0.0 2.5e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX94920.1 - 1.8e-07 32.0 1.4 3.2e-07 31.2 0.0 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Sox_C_TAD PF12067.3 KFX94920.1 - 0.067 13.3 0.3 9.3 6.3 0.0 2.2 1 1 1 2 2 2 0 Sox C-terminal transactivation domain AMP-binding PF00501.23 KFX94921.1 - 8.8e-25 86.9 0.0 1.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme OTU PF02338.14 KFX94922.1 - 6.8e-18 65.4 0.0 6.8e-18 65.4 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFX94922.1 - 9e-05 21.9 0.3 0.051 12.9 0.0 3.0 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF4375 PF14300.1 KFX94922.1 - 0.097 12.6 3.7 0.44 10.5 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) DUF966 PF06136.8 KFX94922.1 - 2 7.7 11.0 2.6 7.3 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TPMT PF05724.6 KFX94923.1 - 1.7e-26 93.0 0.0 2.5e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KFX94923.1 - 3.5e-06 27.5 0.0 5.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX94923.1 - 6.5e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX94923.1 - 0.00013 21.6 0.0 0.00098 18.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX94923.1 - 0.0036 17.0 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX94923.1 - 0.0036 17.7 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KFX94923.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB SHMT PF00464.14 KFX94924.1 - 3.5e-200 664.4 0.0 4.4e-200 664.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase adh_short PF00106.20 KFX94924.1 - 2.5e-25 89.3 0.0 6.4e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX94924.1 - 2.2e-24 86.5 0.0 3.8e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX94924.1 - 1.9e-06 27.6 0.0 7.8e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 KR domain DUF3554 PF12074.3 KFX94926.1 - 8.1e-80 268.7 2.3 8.1e-80 268.7 1.6 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KFX94926.1 - 5.6e-59 198.1 6.8 5.6e-59 198.1 4.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.17 KFX94926.1 - 1.3e-30 102.7 26.8 0.024 14.7 0.0 20.4 22 0 0 22 22 22 6 HEAT repeat HEAT_2 PF13646.1 KFX94926.1 - 9e-30 102.8 48.4 6.9e-09 35.8 0.0 15.2 7 3 10 17 17 17 9 HEAT repeats HEAT_EZ PF13513.1 KFX94926.1 - 9.7e-29 99.1 47.1 1.5e-05 25.3 0.0 20.2 11 5 11 22 22 22 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFX94926.1 - 5.1e-14 52.4 0.0 1.7 9.0 0.0 10.1 8 3 2 10 10 10 3 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KFX94926.1 - 2.2e-10 40.7 3.2 0.0028 17.5 0.0 7.0 8 1 0 8 8 8 2 Parkin co-regulated protein CLASP_N PF12348.3 KFX94926.1 - 4.6e-10 39.2 0.0 0.054 12.8 0.0 5.7 5 2 1 6 6 6 3 CLASP N terminal Cnd1 PF12717.2 KFX94926.1 - 6.2e-07 29.4 0.9 1.8 8.4 0.0 7.1 7 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KFX94926.1 - 2.5 6.7 16.1 0.33 9.6 0.2 5.7 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal HA2 PF04408.18 KFX94927.1 - 8.2e-17 61.1 0.0 2.6e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX94927.1 - 1.8e-12 46.9 0.0 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX94927.1 - 6.8e-11 41.9 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX94927.1 - 1.4e-07 31.7 0.5 3.7e-07 30.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain OB_NTP_bind PF07717.11 KFX94927.1 - 1e-06 28.5 0.1 3.7e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 KFX94927.1 - 0.00059 19.3 0.0 0.0022 17.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX94927.1 - 0.0022 18.2 0.1 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.13 KFX94927.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 KFX94927.1 - 0.02 13.9 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 KFX94927.1 - 0.021 13.6 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 KFX94927.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 KFX94927.1 - 0.13 11.3 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX94927.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain ACPS PF01648.15 KFX94931.1 - 1e-05 25.3 0.1 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily RRM_5 PF13893.1 KFX94933.1 - 8.3e-05 22.3 0.1 0.0041 16.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX94933.1 - 0.028 14.3 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 KFX94934.1 - 2.5e-16 60.0 0.0 9.9e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX94934.1 - 5.9e-05 22.7 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFX94934.1 - 0.00022 21.3 0.3 0.0022 18.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KFX94934.1 - 0.0012 18.5 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFX94934.1 - 0.0027 18.4 2.5 0.0083 16.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX94934.1 - 0.028 14.4 0.3 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KFX94934.1 - 0.03 14.2 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SOBP PF15279.1 KFX94934.1 - 3.4 7.9 16.1 7.5 6.8 11.2 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_transf_36 PF06165.6 KFX94935.1 - 1.3e-21 76.4 0.0 3.5e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 36 GT36_AF PF06205.6 KFX94935.1 - 0.00088 18.9 0.0 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family Bac_rhamnosid PF05592.6 KFX94935.1 - 0.0021 16.3 0.2 0.0041 15.4 0.0 1.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase GDE_C PF06202.9 KFX94935.1 - 0.0047 15.6 0.0 0.011 14.4 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF608 PF04685.8 KFX94935.1 - 0.048 12.3 0.3 0.077 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 ABC2_membrane PF01061.19 KFX94936.1 - 3.9e-89 297.3 58.9 1.1e-46 158.6 13.0 3.3 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.22 KFX94936.1 - 2.4e-38 131.5 0.0 3.4e-19 69.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFX94936.1 - 2e-28 98.0 1.2 2.1e-24 85.1 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter AAA_25 PF13481.1 KFX94936.1 - 9.8e-07 28.3 0.1 0.061 12.7 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KFX94936.1 - 1.1e-06 28.5 0.0 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KFX94936.1 - 2.9e-06 27.4 1.6 0.039 13.9 0.0 4.0 3 1 0 4 4 4 1 AAA domain ABC_trans_N PF14510.1 KFX94936.1 - 9.2e-06 25.6 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal FtsK_SpoIIIE PF01580.13 KFX94936.1 - 1.5e-05 24.5 0.1 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KFX94936.1 - 1.8e-05 25.0 0.0 0.005 17.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KFX94936.1 - 2.6e-05 23.4 0.0 0.00072 18.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KFX94936.1 - 3.1e-05 23.5 0.2 0.001 18.5 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KFX94936.1 - 5.9e-05 23.2 0.0 0.097 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX94936.1 - 0.00014 21.8 0.5 0.0087 16.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KFX94936.1 - 0.00018 20.9 0.5 0.16 11.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFX94936.1 - 0.00061 19.7 0.2 0.27 11.2 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KFX94936.1 - 0.0012 18.8 1.4 0.0029 17.6 0.1 2.3 3 0 0 3 3 1 1 AAA domain UPF0079 PF02367.12 KFX94936.1 - 0.0014 18.2 4.9 0.077 12.6 0.3 3.3 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFX94936.1 - 0.0015 18.1 0.5 0.46 10.1 0.3 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 KFX94936.1 - 0.0034 16.9 0.1 0.28 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX94936.1 - 0.0036 16.5 0.2 0.031 13.5 0.0 2.5 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX94936.1 - 0.0037 18.0 0.0 0.068 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX94936.1 - 0.005 16.3 1.5 1.5 8.1 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain Miro PF08477.8 KFX94936.1 - 0.015 15.8 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KFX94936.1 - 0.018 15.2 0.3 10 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFX94936.1 - 0.021 13.7 0.1 3.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.13 KFX94936.1 - 0.039 12.9 0.4 0.33 9.9 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_19 PF13245.1 KFX94936.1 - 0.053 13.2 0.3 8.6 6.1 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KFX94936.1 - 0.055 13.6 0.0 9.2 6.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.17 KFX94936.1 - 0.091 11.6 1.1 3.9 6.2 0.4 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KFX94936.1 - 0.11 11.5 0.0 6 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KFX94936.1 - 0.16 11.4 0.5 0.47 9.9 0.2 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sugar_tr PF00083.19 KFX94937.1 - 4.9e-116 387.9 22.7 5.6e-116 387.7 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94937.1 - 4.4e-27 94.7 22.7 1.5e-20 73.2 1.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4094 PF13334.1 KFX94937.1 - 0.017 15.5 0.0 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) GMC_oxred_C PF05199.8 KFX94938.1 - 5.3e-29 101.3 0.0 8.6e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KFX94938.1 - 2e-26 92.8 0.0 3.1e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KFX94938.1 - 5.2e-05 23.1 0.3 0.00014 21.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX94938.1 - 0.00072 18.5 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX94938.1 - 0.0009 18.2 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX94938.1 - 0.0084 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 KFX94938.1 - 0.021 14.3 0.6 0.047 13.1 0.4 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KFX94938.1 - 0.035 13.9 0.1 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX94938.1 - 0.086 11.2 0.6 0.13 10.7 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans_2 PF11951.3 KFX94939.1 - 1.6e-44 152.0 6.1 1.9e-44 151.8 4.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94939.1 - 6.1e-10 38.8 6.5 1.2e-09 37.8 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 KFX94940.1 - 4e-13 49.7 0.3 6.1e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX94940.1 - 8.4e-07 29.2 0.1 0.0075 16.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX94940.1 - 8.9e-07 29.2 0.2 0.00012 22.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX94940.1 - 0.00094 18.9 1.1 3.6 7.3 0.0 4.0 5 0 0 5 5 5 1 FAD-NAD(P)-binding DAO PF01266.19 KFX94940.1 - 1.1 8.0 5.8 1.1 8.0 0.0 2.8 2 2 1 3 3 3 0 FAD dependent oxidoreductase Chitin_synth_1 PF01644.12 KFX94941.1 - 3.7e-86 286.9 0.2 9.3e-86 285.6 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase DUF1993 PF09351.5 KFX94941.1 - 3.1e-47 160.5 0.0 5.2e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Chitin_synth_1N PF08407.6 KFX94941.1 - 8.3e-33 111.9 0.1 1.7e-32 110.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFX94941.1 - 1.7e-24 86.1 4.1 3.1e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFX94941.1 - 3.5e-10 39.9 0.3 3.5e-10 39.9 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFX94941.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CD99L2 PF12301.3 KFX94942.1 - 0.0068 16.1 0.5 0.0068 16.1 0.4 2.6 3 0 0 3 3 3 1 CD99 antigen like protein 2 Amino_oxidase PF01593.19 KFX94944.1 - 1.4e-85 288.0 0.0 2.7e-85 287.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box PF00505.14 KFX94944.1 - 8.3e-09 35.5 0.2 1.9e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box SWIRM PF04433.12 KFX94944.1 - 2.2e-07 30.9 0.0 5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KFX94944.1 - 9.2e-07 28.8 0.2 2.3e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.5 KFX94944.1 - 2.8e-06 27.6 0.2 5.3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain DUF2057 PF09829.4 KFX94944.1 - 0.05 13.2 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DAO PF01266.19 KFX94944.1 - 0.059 12.2 0.2 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sec1 PF00995.18 KFX94945.1 - 1.3e-131 440.0 0.0 1.6e-131 439.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family UQ_con PF00179.21 KFX94947.1 - 8.4e-15 54.4 0.0 1.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFX94947.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 1 0 1 1 1 1 RWD domain DUF4551 PF15087.1 KFX94947.1 - 1 7.6 3.3 1.2 7.3 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Na_Ca_ex PF01699.19 KFX94964.1 - 1.3e-43 148.0 33.2 5.9e-22 77.7 8.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MFS_1 PF07690.11 KFX94971.1 - 1.3e-32 112.8 60.2 6e-30 104.1 27.4 3.4 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX94971.1 - 1.3e-09 37.1 12.3 1.3e-09 37.1 8.5 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter p450 PF00067.17 KFX94972.1 - 1.3e-67 228.3 0.0 1.7e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 KFX94974.1 - 9.3e-07 28.5 0.0 3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX94974.1 - 7.9e-06 25.4 0.1 1.7e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KFX94974.1 - 0.091 12.7 0.3 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding Cupin_3 PF05899.7 KFX94974.1 - 0.11 11.8 0.1 0.81 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AMP-binding PF00501.23 KFX94975.1 - 7.5e-177 587.8 0.0 4.1e-92 308.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFX94975.1 - 8.8e-54 182.3 0.0 1.6e-31 109.2 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFX94975.1 - 3.7e-17 62.3 2.3 1.5e-07 31.5 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX94975.1 - 2.1e-13 50.9 0.0 2.8e-07 31.3 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Med4 PF10018.4 KFX94976.1 - 0.085 12.2 0.4 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Roughex PF06020.6 KFX94981.1 - 2.5 6.6 16.2 0.72 8.4 9.5 1.3 1 1 0 1 1 1 0 Drosophila roughex protein DNA_pol_A_exo1 PF01612.15 KFX94982.1 - 1.1e-05 25.0 0.0 3.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease Acyl_transf_1 PF00698.16 KFX94988.1 - 1.2e-09 37.9 0.0 8.4e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Gram_pos_anchor PF00746.16 KFX94995.1 - 3.6 7.5 6.4 0.76 9.6 0.3 2.2 2 0 0 2 2 2 0 Gram positive anchor Rick_17kDa_Anti PF05433.10 KFX94995.1 - 9.4 6.0 12.9 6.1 6.6 3.5 2.4 1 1 1 2 2 2 0 Glycine zipper 2TM domain Pkinase PF00069.20 KFX94996.1 - 1e-48 165.7 0.0 1.5e-28 99.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94996.1 - 2.9e-21 75.7 0.0 1.6e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFX94996.1 - 0.0043 16.8 0.1 0.01 15.5 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFX94996.1 - 0.095 12.4 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Tricorn protease PDZ domain Pox_ser-thr_kin PF05445.6 KFX94996.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FKBP_C PF00254.23 KFX94997.1 - 1.2e-30 105.3 0.0 4e-30 103.6 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FA_desaturase PF00487.19 KFX94997.1 - 5.6 6.3 4.5 8.4 5.7 3.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase IMS PF00817.15 KFX94998.1 - 3.2e-41 140.6 0.0 5.7e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family CSTF2_hinge PF14327.1 KFX94998.1 - 1.1e-26 92.6 0.4 1.1e-26 92.6 0.3 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KFX94998.1 - 9e-22 76.5 0.0 2.3e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMS_C PF11799.3 KFX94998.1 - 1.4e-17 63.7 0.0 4.6e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain RRM_6 PF14259.1 KFX94998.1 - 4.5e-15 55.3 0.0 1.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4414 PF14377.1 KFX94998.1 - 2.7e-13 49.7 7.9 4.4e-06 26.5 0.1 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) BRCT PF00533.21 KFX94998.1 - 1.1e-08 35.0 0.0 6.8e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRM_5 PF13893.1 KFX94998.1 - 5.1e-07 29.4 0.0 9.7e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KFX94998.1 - 9e-07 28.0 4.5 9e-07 28.0 3.1 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal PTCB-BRCT PF12738.2 KFX94998.1 - 5.3e-05 22.9 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 KFX94998.1 - 0.00072 19.4 0.3 0.0058 16.6 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif DUF1805 PF08827.6 KFX94998.1 - 0.15 11.8 0.0 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Band_7 PF01145.20 KFX94999.1 - 5.4e-23 81.8 2.4 7.6e-23 81.3 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 KFX94999.1 - 0.14 11.3 2.7 0.21 10.8 1.9 1.3 1 1 0 1 1 1 0 MraW methylase family ubiquitin PF00240.18 KFX95000.1 - 8.3e-26 89.1 0.2 9.1e-26 89.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFX95000.1 - 1.5e-15 56.6 0.2 1.6e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFX95000.1 - 2.7e-05 24.3 0.0 7.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain SnoaL PF07366.7 KFX95001.1 - 0.0028 17.2 0.0 0.0058 16.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 KFX95001.1 - 0.17 11.1 0.0 4.5 6.5 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Elongin_A PF06881.6 KFX95002.1 - 2.3e-22 79.4 2.5 6.5e-22 77.9 1.2 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF385 PF04075.9 KFX95002.1 - 0.029 14.3 0.4 0.075 12.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF385) RE_MjaI PF09568.5 KFX95002.1 - 0.14 11.7 1.5 0.29 10.6 1.1 1.4 1 0 0 1 1 1 0 MjaI restriction endonuclease DUF4449 PF14613.1 KFX95002.1 - 0.16 11.8 0.2 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) DUF4219 PF13961.1 KFX95018.1 - 2.9e-15 55.2 0.1 3e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4219) UBN2 PF14223.1 KFX95018.1 - 0.0015 18.2 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 KFX95018.1 - 0.0047 16.4 0.0 0.56 9.7 0.0 2.7 3 0 0 3 3 3 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KFX95019.1 - 5.8e-09 35.1 3.7 9.7e-09 34.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Zn_clus PF00172.13 KFX95023.1 - 3.7e-11 42.7 9.8 5.1e-11 42.2 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hamartin PF04388.7 KFX95023.1 - 1.1 7.8 7.1 1.1 7.8 4.9 1.1 1 0 0 1 1 1 0 Hamartin protein SSP160 PF06933.6 KFX95023.1 - 3.6 5.4 11.6 4.2 5.2 8.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mito_fiss_reg PF05308.6 KFX95023.1 - 4 6.7 9.0 4.3 6.6 6.2 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFX95023.1 - 5.3 6.2 11.3 4.8 6.3 6.3 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF221 PF02714.10 KFX95047.1 - 4.2e-95 318.3 13.6 6.7e-95 317.6 9.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFX95047.1 - 3.2e-37 127.4 0.2 8.9e-37 126.0 0.1 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFX95047.1 - 5.1e-16 58.9 0.0 1.1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) WD40 PF00400.27 KFX95073.1 - 3.9e-27 93.1 10.4 1.6e-07 30.9 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 KFX95073.1 - 0.0015 16.7 0.4 0.0052 14.9 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cyclin_N PF00134.18 KFX95073.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain HA2 PF04408.18 KFX95074.1 - 9.6e-24 83.3 0.0 3.6e-23 81.5 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFX95074.1 - 4.9e-23 81.1 0.0 2.4e-22 78.9 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFX95074.1 - 8.4e-13 47.9 0.0 2.1e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX95074.1 - 2.2e-07 30.5 0.0 5.4e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX95074.1 - 0.001 19.2 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFX95074.1 - 0.0011 17.8 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KFX95074.1 - 0.002 17.1 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KFX95074.1 - 0.0022 17.8 0.0 0.83 9.4 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 KFX95074.1 - 0.023 14.1 0.1 0.054 12.9 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KFX95074.1 - 0.026 14.2 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.7 KFX95074.1 - 0.033 13.8 0.4 0.33 10.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain GAD PF02938.9 KFX95074.1 - 0.039 14.0 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 GAD domain NB-ARC PF00931.17 KFX95074.1 - 0.049 12.4 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 KFX95074.1 - 0.051 13.8 0.9 0.44 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KFX95074.1 - 0.053 13.4 0.1 0.31 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFX95074.1 - 0.063 13.5 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 1 0 ABC transporter DUF1570 PF07607.6 KFX95074.1 - 0.17 11.8 1.4 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) zf-CCCH_2 PF14608.1 KFX95076.1 - 8.7e-15 54.0 49.7 7.3e-08 32.1 6.8 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KFX95076.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) PAT1 PF09770.4 KFX95076.1 - 7.9 4.5 16.7 9 4.3 11.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAP_GLY PF01302.20 KFX95085.1 - 1.3e-21 76.0 2.7 2e-21 75.4 1.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KFX95085.1 - 4.2e-21 74.9 0.0 6.4e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KFX95085.1 - 8.8e-05 21.8 0.0 0.0002 20.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.26 KFX95086.1 - 3.5e-12 46.1 3.6 5.3e-09 35.9 0.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX95086.1 - 5.9e-07 29.4 3.8 0.00042 20.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.7 KFX95087.1 - 2.2e-08 34.4 0.0 3.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX95087.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX95087.1 - 4.4e-06 27.0 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX95087.1 - 0.00036 21.0 0.0 0.00063 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX95087.1 - 0.00054 19.5 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX95087.1 - 0.0025 18.1 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX95087.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 KFX95087.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UCH PF00443.24 KFX95088.1 - 4.5e-21 75.1 0.0 1.2e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX95088.1 - 1.9e-14 53.8 0.1 1.8e-13 50.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 KFX95088.1 - 0.033 13.6 1.9 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.1 KFX95088.1 - 0.084 12.8 0.2 1.6 8.6 0.1 2.8 2 1 0 2 2 2 0 CpXC protein Y_phosphatase PF00102.22 KFX95089.1 - 3.9e-59 199.8 0.0 3.9e-58 196.5 0.0 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KFX95089.1 - 9.2e-13 48.5 0.0 3.7e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KFX95089.1 - 0.048 13.9 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 KFX95089.1 - 0.097 12.2 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.24 KFX95090.1 - 5.4e-44 149.5 0.0 8.5e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX95090.1 - 3.2e-08 33.3 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX95090.1 - 1.2e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFX95090.1 - 2.9e-06 27.4 0.1 6.5e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX95090.1 - 5.4e-06 26.5 0.1 0.00025 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX95090.1 - 6.9e-05 23.6 0.0 0.00015 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX95090.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFX95090.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFX95090.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFX95090.1 - 0.00087 18.1 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KFX95090.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFX95090.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX95090.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KFX95090.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFX95090.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFX95090.1 - 0.0063 15.6 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 KFX95090.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFX95090.1 - 0.008 16.4 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KFX95090.1 - 0.017 14.5 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFX95090.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KFX95090.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KFX95090.1 - 0.021 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFX95090.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX95090.1 - 0.03 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFX95090.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFX95090.1 - 0.049 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFX95090.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 KFX95090.1 - 0.082 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NACHT PF05729.7 KFX95090.1 - 0.1 12.2 0.0 0.55 9.8 0.0 2.0 1 1 0 2 2 2 0 NACHT domain Na_Ca_ex PF01699.19 KFX95091.1 - 7.9e-29 100.0 25.9 3.8e-17 62.1 7.6 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KFX95091.1 - 1.2e-14 54.4 13.5 1.2e-14 54.4 9.4 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF307) OMPdecase PF00215.19 KFX95092.1 - 1.2e-86 289.8 0.1 1.6e-86 289.3 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MR_MLE_C PF13378.1 KFX95093.1 - 6.2e-19 68.0 0.0 3.2e-18 65.7 0.0 2.2 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFX95093.1 - 2.3e-12 47.2 0.0 6.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFX95093.1 - 0.0021 18.0 0.2 0.0064 16.4 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KFX95093.1 - 0.0023 16.8 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DHDPS PF00701.17 KFX95094.1 - 9.3e-40 136.0 0.0 1.2e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF218 PF02698.12 KFX95094.1 - 0.11 12.0 0.3 0.35 10.3 0.1 1.9 2 1 0 2 2 2 0 DUF218 domain RNA_polI_A34 PF08208.6 KFX95101.1 - 1.1e-13 51.2 10.0 1.3e-13 51.0 7.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Paf1 PF03985.8 KFX95101.1 - 0.26 9.9 7.3 0.3 9.7 5.1 1.0 1 0 0 1 1 1 0 Paf1 RNase_H2-Ydr279 PF09468.5 KFX95101.1 - 0.55 9.3 7.3 0.56 9.3 5.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Abhydrolase_6 PF12697.2 KFX95102.1 - 8.3e-09 35.6 2.5 1.5e-08 34.8 1.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX95102.1 - 0.011 14.4 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFX95102.1 - 0.097 12.4 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family CFEM PF05730.6 KFX95103.1 - 1.6e-13 50.2 9.9 2.7e-13 49.5 6.9 1.4 1 0 0 1 1 1 1 CFEM domain Microtub_assoc PF07989.6 KFX95113.1 - 0.12 12.1 10.0 0.17 11.6 6.2 1.8 1 1 0 1 1 1 0 Microtubule associated UPF0242 PF06785.6 KFX95113.1 - 2 6.9 8.8 3.2 6.3 6.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Collagen PF01391.13 KFX95114.1 - 0.036 13.6 1.7 0.046 13.2 1.1 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Snf7 PF03357.16 KFX95115.1 - 1.7e-43 147.9 11.3 1.9e-43 147.7 7.8 1.0 1 0 0 1 1 1 1 Snf7 Reo_sigmaC PF04582.7 KFX95115.1 - 0.0087 15.2 4.0 0.11 11.6 0.4 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF4201 PF13870.1 KFX95115.1 - 0.023 14.1 6.5 0.032 13.6 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 KFX95115.1 - 0.044 13.6 5.2 0.029 14.1 2.4 1.6 1 1 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.7 KFX95115.1 - 0.055 13.7 9.0 1.1 9.5 1.3 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1395 PF07160.7 KFX95115.1 - 0.06 12.8 4.2 0.12 11.8 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) DUF1409 PF07197.7 KFX95115.1 - 0.078 13.0 0.7 0.67 10.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) DUF342 PF03961.8 KFX95115.1 - 0.12 10.8 7.8 0.14 10.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KFX95115.1 - 1.5 8.9 7.8 5 7.3 2.5 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.9 KFX95115.1 - 2.3 8.1 13.0 1.7 8.5 5.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.6 KFX95115.1 - 2.6 8.0 5.9 11 5.9 0.0 3.1 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 KFX95115.1 - 6.9 6.5 7.5 28 4.5 2.8 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SAPS PF04499.10 KFX95117.1 - 3.8e-200 665.5 1.9 2.9e-199 662.6 0.0 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Cuticle_3 PF11018.3 KFX95117.1 - 1.4 9.0 11.2 2.3 8.3 7.8 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 Homeobox_KN PF05920.6 KFX95118.1 - 1.3e-19 69.6 0.1 2.3e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFX95118.1 - 3.9e-08 32.7 0.3 5.5e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 Homeobox domain GatB_N PF02934.10 KFX95119.1 - 5e-100 334.0 0.0 6.7e-100 333.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KFX95119.1 - 0.13 11.9 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 GatB domain FKBP_C PF00254.23 KFX95121.1 - 1.6e-26 92.1 0.0 1.9e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FMN_dh PF01070.13 KFX95125.1 - 8.9e-100 333.9 0.0 2.5e-99 332.4 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFX95125.1 - 3.7e-19 68.3 0.0 7.8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KFX95125.1 - 4.8e-07 28.9 0.1 0.00023 20.1 0.0 3.0 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFX95125.1 - 3.2e-06 26.3 0.0 5.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KFX95125.1 - 0.042 13.1 0.1 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 KFX95125.1 - 0.045 12.8 0.1 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 KFX95125.1 - 0.087 11.9 0.4 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.16 KFX95125.1 - 0.1 11.5 0.0 0.41 9.5 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Sugar_tr PF00083.19 KFX95126.1 - 4.8e-89 298.9 25.5 5.5e-89 298.8 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95126.1 - 3.9e-30 104.7 19.3 3.9e-30 104.7 13.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KFX95127.1 - 1.1e-36 126.3 28.1 4.1e-36 124.4 19.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KFX95128.1 - 9.4e-10 38.0 0.0 0.004 16.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFX95128.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX95128.1 - 0.053 13.9 0.0 0.37 11.2 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX95128.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Rsm22 PF09243.5 KFX95129.1 - 5.7e-34 117.4 0.0 7.8e-33 113.6 0.0 2.6 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_S14 PF00253.16 KFX95134.1 - 8.7e-18 63.4 0.3 2e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e adh_short PF00106.20 KFX95135.1 - 1e-14 54.8 0.9 9.8e-09 35.3 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase Acetyltransf_1 PF00583.19 KFX95135.1 - 2.3e-05 24.3 0.0 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family KR PF08659.5 KFX95135.1 - 0.00014 21.6 0.3 0.031 13.9 0.0 3.6 4 0 0 4 4 4 1 KR domain adh_short_C2 PF13561.1 KFX95135.1 - 0.00025 20.9 0.0 0.0011 18.8 0.0 2.0 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_10 PF13673.1 KFX95135.1 - 0.033 14.3 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rpp20 PF12328.3 KFX95136.1 - 2.1e-30 105.2 0.8 2.7e-30 104.9 0.6 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KFX95136.1 - 7.4e-16 57.5 0.1 1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.4 KFX95137.1 - 5e-53 179.9 0.0 7.2e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Thioredoxin PF00085.15 KFX95138.1 - 7.7e-27 93.0 0.0 1.1e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFX95138.1 - 2.3e-07 30.8 0.1 8.3e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFX95138.1 - 4e-07 30.2 0.1 1.7e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFX95138.1 - 9.8e-05 21.9 0.1 0.044 13.3 0.1 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 KFX95138.1 - 0.00023 20.8 0.1 0.08 12.6 0.0 2.1 1 1 1 2 2 2 2 AhpC/TSA family HyaE PF07449.6 KFX95138.1 - 0.0047 16.8 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF2763 PF10961.3 KFX95138.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) Thioredoxin_7 PF13899.1 KFX95138.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KFX95138.1 - 0.026 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 KFX95138.1 - 0.055 13.4 0.1 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 KFX95138.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Methyltrn_RNA_3 PF02598.12 KFX95139.1 - 2.2e-53 181.4 0.0 2.6e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Aconitase_B_N PF11791.3 KFX95139.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Aconitate B N-terminal domain HNH_2 PF13391.1 KFX95140.1 - 2e-13 49.8 0.0 3.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_2_N PF02837.13 KFX95141.1 - 6.3e-12 45.3 0.0 2.3e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX95141.1 - 7.1e-07 29.6 0.0 6.6e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFX95141.1 - 1.1e-05 24.5 0.0 3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Ribosomal_L7Ae PF01248.21 KFX95153.1 - 9.5e-22 76.3 1.1 3.1e-21 74.6 0.7 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Apt1 PF10351.4 KFX95154.1 - 6.7 5.4 13.2 0.31 9.8 3.1 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain SCP2 PF02036.12 KFX95158.1 - 6.4e-24 84.1 1.0 7.4e-24 83.9 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KFX95158.1 - 8.6e-08 32.2 0.2 1.2e-07 31.7 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal EamA PF00892.15 KFX95159.1 - 2e-08 34.2 27.1 0.00012 22.0 9.4 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFX95159.1 - 2e-05 24.7 2.4 2e-05 24.7 1.7 3.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF1469 PF07332.6 KFX95159.1 - 0.00047 19.8 7.8 0.017 14.8 0.7 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1469) TPT PF03151.11 KFX95159.1 - 0.12 12.0 11.6 0.24 11.0 4.4 2.7 2 0 0 2 2 2 0 Triose-phosphate Transporter family SH3_9 PF14604.1 KFX95166.1 - 1.6e-05 24.4 0.1 2.7e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFX95166.1 - 0.0026 17.1 0.1 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFX95166.1 - 0.12 11.8 0.8 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Variant SH3 domain Glyco_hydro_32N PF00251.15 KFX95168.1 - 7.7e-38 130.5 0.0 1.4e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KFX95168.1 - 2.6e-13 50.1 0.1 4.4e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 KFX95168.1 - 0.11 11.5 0.0 2.3 7.2 0.0 2.6 2 1 1 3 3 3 0 Glycosyl hydrolases family 43 Amidohydro_1 PF01979.15 KFX95171.1 - 1.7e-15 57.5 0.0 2.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX95171.1 - 6.4e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFX95171.1 - 2.6e-06 27.6 0.3 4.1e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Amidohydrolase AA_permease_2 PF13520.1 KFX95172.1 - 1.3e-54 185.3 53.5 1.7e-54 185.0 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX95172.1 - 4.6e-17 61.5 47.0 8e-17 60.7 32.6 1.3 1 1 0 1 1 1 1 Amino acid permease Med17 PF10156.4 KFX95178.1 - 1.9e-59 201.1 0.0 2.1e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 KFX95179.1 - 1.4e-159 529.5 2.4 4.9e-117 389.9 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.3 KFX95179.1 - 0.057 12.9 0.4 0.67 9.4 0.0 2.3 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Ank_2 PF12796.2 KFX95180.1 - 9.6e-89 291.8 24.1 2.9e-19 69.1 0.3 6.6 2 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95180.1 - 2.4e-62 203.8 35.3 3.9e-06 26.3 0.0 13.1 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 KFX95180.1 - 1.4e-52 175.2 21.5 6.2e-10 39.3 0.1 9.1 3 3 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95180.1 - 3.9e-47 153.5 18.9 0.00074 19.5 0.0 12.9 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.1 KFX95180.1 - 8.5e-35 118.0 20.2 0.00016 21.7 0.2 10.6 1 1 10 11 11 11 11 Ankyrin repeats (many copies) NACHT PF05729.7 KFX95180.1 - 1.9e-06 27.6 1.2 2.1e-05 24.2 0.1 2.4 1 1 1 2 2 2 1 NACHT domain Pkinase PF00069.20 KFX95183.1 - 1.8e-63 214.1 0.0 2.9e-39 134.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95183.1 - 3.6e-27 95.0 0.0 6e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KFX95183.1 - 1.8e-12 47.2 0.1 3.5e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KFX95183.1 - 6.5e-08 31.8 0.1 4.5e-06 25.8 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KFX95183.1 - 7.5e-08 32.3 0.3 0.0032 17.2 0.1 3.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KFX95183.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 KFX95183.1 - 0.069 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.6 KFX95183.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ubiquitin PF00240.18 KFX95203.1 - 3.1e-169 548.6 31.3 1.6e-33 113.9 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 KFX95203.1 - 3.6e-97 318.1 28.4 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFX95203.1 - 1.7e-29 101.9 15.8 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFX95203.1 - 7.5e-27 94.0 3.2 0.001 18.7 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFX95203.1 - 6.2e-17 61.4 4.9 0.17 11.7 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFX95203.1 - 1.1e-16 60.7 4.7 0.18 12.0 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KFX95203.1 - 2.4e-13 49.9 0.0 2 8.4 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 KFX95203.1 - 7.7e-08 31.7 1.4 2.8 7.0 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 KFX95203.1 - 1.9e-07 30.8 9.3 6.3 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 KFX95203.1 - 1.6e-05 24.5 8.5 19 5.1 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 KFX95203.1 - 0.00013 21.3 0.0 65 2.9 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 KFX95203.1 - 0.00032 19.1 18.9 3.1 5.9 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 KFX95203.1 - 0.00038 20.7 1.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 KFX95203.1 - 0.02 14.7 19.9 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 KFX95203.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 KFX95203.1 - 0.058 13.3 11.8 63 3.6 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 KFX95203.1 - 0.13 12.3 17.1 58 3.8 0.1 7.0 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 KFX95203.1 - 0.78 9.7 11.2 1.3e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Zn_clus PF00172.13 KFX95204.1 - 0.0062 16.4 7.7 0.0062 16.4 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 KFX95204.1 - 0.35 9.8 0.0 0.54 9.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein WaaY PF06176.6 KFX95205.1 - 0.0018 17.5 0.1 0.0032 16.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 KFX95205.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltrans PF00432.16 KFX95206.1 - 1.4e-33 114.1 23.9 1e-08 34.6 0.5 5.8 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFX95206.1 - 2e-23 82.9 0.0 6.3e-14 52.3 0.0 4.1 1 1 4 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFX95206.1 - 4.4e-06 26.6 0.0 4.9e-05 23.2 0.0 2.7 2 1 0 2 2 2 1 Prenyltransferase-like DND1_DSRM PF14709.1 KFX95207.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KFX95207.1 - 0.00054 20.4 0.0 0.00091 19.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif CGI-121 PF08617.5 KFX95212.1 - 5.1e-51 172.5 0.0 6.2e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 CP2 PF04516.10 KFX95213.1 - 4.5e-85 284.4 0.0 6.9e-85 283.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 KFX95213.1 - 0.015 13.8 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Tektin family Phage_G PF02306.10 KFX95213.1 - 0.042 13.4 0.1 0.042 13.4 0.1 1.9 2 0 0 2 2 2 0 Major spike protein (G protein) PseudoU_synth_2 PF00849.17 KFX95220.1 - 2e-25 89.5 0.0 3.3e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.1 KFX95220.1 - 0.0052 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Mut7-C ubiquitin S4 PF01479.20 KFX95220.1 - 0.15 11.4 1.1 0.31 10.5 0.7 1.5 1 0 0 1 1 1 0 S4 domain Microtub_assoc PF07989.6 KFX95226.1 - 1.6e-18 66.2 9.3 1.6e-18 66.2 6.5 7.7 9 1 2 11 11 11 1 Microtubule associated Reo_sigmaC PF04582.7 KFX95226.1 - 1.7e-05 24.1 22.4 0.00015 21.0 1.3 5.8 2 1 4 6 6 6 4 Reovirus sigma C capsid protein WEMBL PF05701.6 KFX95226.1 - 0.00041 18.9 57.4 0.00041 18.9 39.8 4.3 2 2 1 3 3 3 1 Weak chloroplast movement under blue light Fib_alpha PF08702.5 KFX95226.1 - 0.084 12.9 51.4 0.67 10.0 3.7 7.2 4 1 4 8 8 8 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 KFX95226.1 - 1.1 9.1 32.1 0.61 9.9 1.4 5.9 5 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus CPSF73-100_C PF11718.3 KFX95229.1 - 0.17 11.2 1.2 0.36 10.1 0.8 1.6 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4129 PF13559.1 KFX95233.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) NnrU PF07298.6 KFX95233.1 - 0.059 12.7 1.4 0.11 11.8 0.9 1.4 1 0 0 1 1 1 0 NnrU protein Yip1 PF04893.12 KFX95233.1 - 0.11 12.0 4.4 0.16 11.4 3.0 1.3 1 0 0 1 1 1 0 Yip1 domain CENP-B_dimeris PF09026.5 KFX95233.1 - 1.1 9.4 6.8 2.3 8.4 4.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S10 PF00450.17 KFX95234.1 - 3.2e-86 290.0 0.3 6.8e-86 289.0 0.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase NAD_binding_10 PF13460.1 KFX95244.1 - 4.4e-13 49.6 0.0 5.3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX95244.1 - 3.8e-11 42.8 0.1 1.6e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX95244.1 - 1.4e-06 27.7 0.5 2.3e-06 27.0 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KFX95244.1 - 1.1e-05 25.3 0.4 2.2e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 KFX95244.1 - 0.0012 19.1 0.1 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KFX95244.1 - 0.0021 17.9 1.3 0.0037 17.1 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KFX95244.1 - 0.0022 16.7 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFX95244.1 - 0.0027 17.9 0.1 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KFX95244.1 - 0.0064 15.4 0.2 0.0083 15.0 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 KFX95244.1 - 0.007 16.2 0.3 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFX95244.1 - 0.011 14.6 0.1 0.026 13.4 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 KFX95244.1 - 0.052 13.1 0.4 0.086 12.3 0.3 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 KFX95244.1 - 0.089 11.6 0.2 1.5 7.6 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.11 KFX95244.1 - 0.1 13.1 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.5 KFX95244.1 - 0.17 11.5 1.3 0.55 9.8 0.9 1.6 1 1 0 1 1 1 0 KR domain Zn_clus PF00172.13 KFX95245.1 - 0.063 13.2 9.8 0.11 12.4 6.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NETI PF14044.1 KFX95245.1 - 0.091 12.2 0.1 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 NETI protein SnoaL_4 PF13577.1 KFX95246.1 - 2.7e-16 59.6 0.1 3e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain RPAP1_N PF08621.5 KFX95249.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 RPAP1-like, N-terminal Aldedh PF00171.17 KFX95252.1 - 1.2e-90 304.1 4.5 1.3e-90 303.9 3.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PUA PF01472.15 KFX95252.1 - 0.018 14.7 0.5 3.5 7.4 0.0 3.0 3 1 0 3 3 3 0 PUA domain AAA_2 PF07724.9 KFX95252.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Fungal_trans PF04082.13 KFX95254.1 - 2.2e-18 66.0 0.6 3.4e-18 65.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95254.1 - 1.3e-06 28.2 8.6 2.8e-06 27.1 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 KFX95257.1 - 2.8e-16 59.3 0.1 4.7e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KFX95257.1 - 4.5e-13 49.3 0.0 1.4e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KFX95257.1 - 6e-09 35.2 0.6 1.1e-08 34.4 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain FAD-oxidase_C PF02913.14 KFX95258.1 - 7.6e-62 208.8 0.0 1.1e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFX95258.1 - 3e-35 120.7 0.5 4.8e-35 120.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.21 KFX95259.1 - 1.2e-54 184.5 0.1 1.6e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX95259.1 - 2.5e-13 49.0 0.1 2.5e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 KFX95259.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.7 KFX95260.1 - 7.4e-15 54.8 16.4 1e-14 54.4 11.3 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 KFX95260.1 - 0.014 15.3 3.9 0.014 15.3 2.7 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 KFX95260.1 - 0.054 12.9 6.3 0.075 12.5 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Imm-NTF2 PF15655.1 KFX95260.1 - 0.13 12.7 0.4 0.2 12.0 0.3 1.5 1 1 0 1 1 1 0 NTF2 fold immunity protein zf-FPG_IleRS PF06827.9 KFX95260.1 - 0.2 11.3 3.9 3.7 7.2 2.9 2.4 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.2 KFX95260.1 - 0.27 11.0 9.0 8.3 6.3 0.0 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KFX95260.1 - 0.35 10.9 12.4 0.24 11.4 6.0 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain HypA PF01155.14 KFX95260.1 - 0.5 10.0 7.8 0.41 10.3 3.7 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C2H2 PF00096.21 KFX95260.1 - 0.58 10.6 9.0 1.5 9.2 0.7 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type LIM PF00412.17 KFX95260.1 - 0.64 10.1 11.9 2.1 8.4 6.9 2.3 1 1 1 2 2 2 0 LIM domain PhnA_Zn_Ribbon PF08274.7 KFX95260.1 - 1.4 8.8 6.6 4 7.3 0.0 3.2 2 1 0 2 2 2 0 PhnA Zinc-Ribbon DZR PF12773.2 KFX95260.1 - 1.4 8.8 9.5 11 5.9 6.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.1 KFX95260.1 - 1.4 9.3 5.1 63 4.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RING_3 PF14369.1 KFX95260.1 - 1.7 8.7 7.0 1.3 9.1 2.4 2.4 1 1 1 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 KFX95260.1 - 3.2 7.4 10.4 5.5 6.7 7.2 1.5 1 0 0 1 1 1 0 Cytochrome c7 zf-RING_4 PF14570.1 KFX95260.1 - 4.1 7.0 10.9 7.4 6.2 0.1 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Evr1_Alr PF04777.8 KFX95260.1 - 4.8 7.1 8.5 55 3.7 5.8 2.6 1 1 0 1 1 1 0 Erv1 / Alr family Helicase_C_3 PF13625.1 KFX95261.1 - 6.5e-28 97.0 0.0 1e-26 93.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX95261.1 - 1.8e-14 53.9 0.0 5.2e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFX95261.1 - 3.8e-12 45.9 0.0 9.1e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFX95261.1 - 6.7e-11 41.5 0.1 1e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KFX95261.1 - 2.1e-06 27.3 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase TrkH PF02386.11 KFX95262.1 - 2e-119 398.3 19.1 4.1e-117 390.7 7.0 2.1 2 0 0 2 2 2 2 Cation transport protein Thi4 PF01946.12 KFX95262.1 - 8.9e-105 348.8 0.0 1.5e-104 348.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KFX95262.1 - 6.7e-06 25.2 0.6 1.2e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX95262.1 - 0.00019 20.4 0.2 0.00033 19.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX95262.1 - 0.00027 20.9 0.2 0.00074 19.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX95262.1 - 0.0026 17.8 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX95262.1 - 0.0037 17.0 0.0 0.0083 15.9 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFX95262.1 - 0.0065 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX95262.1 - 0.043 12.6 0.7 0.072 11.9 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain DUF4266 PF14086.1 KFX95262.1 - 0.78 10.2 5.0 4.1 7.9 3.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Asparaginase PF00710.15 KFX95263.1 - 6.5e-98 327.4 0.0 8.6e-98 327.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KFX95263.1 - 3.7e-12 46.4 1.3 8e-12 45.3 0.9 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX95263.1 - 1.4e-09 38.1 0.3 9.4e-08 32.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX95263.1 - 2.9e-09 36.8 0.3 1.2e-08 34.8 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFX95263.1 - 1.4e-08 34.0 1.2 1.3e-07 31.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFX95263.1 - 8.8e-06 25.4 0.1 0.00015 21.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Nramp PF01566.13 KFX95266.1 - 1.4e-55 188.5 9.5 2.1e-55 188.0 6.6 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF2668 PF10873.3 KFX95266.1 - 1.4 9.0 9.8 3.4 7.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) Cellulase PF00150.13 KFX95267.1 - 4.4e-08 32.6 0.2 6.1e-07 28.9 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lum_binding PF00677.12 KFX95268.1 - 7.1e-40 134.7 0.5 6.7e-21 73.9 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain PGM_PMM_I PF02878.11 KFX95269.1 - 7.7e-19 67.5 0.1 5.1e-09 35.7 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFX95269.1 - 1.8e-15 57.0 0.1 7.4e-15 55.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFX95269.1 - 7.8e-14 51.4 0.9 2.3e-13 49.9 0.4 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KFX95269.1 - 0.0002 21.3 0.1 0.00064 19.7 0.1 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ERCC4 PF02732.10 KFX95270.1 - 6.5e-30 103.7 0.1 1.3e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KFX95270.1 - 0.00048 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HTH_45 PF14947.1 KFX95270.1 - 0.062 13.1 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix Ank_2 PF12796.2 KFX95275.1 - 2.8e-49 165.3 1.0 1.9e-17 63.3 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95275.1 - 1.7e-47 156.9 3.9 5.7e-07 29.0 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFX95275.1 - 1e-37 127.8 5.2 2.5e-09 37.4 0.1 5.1 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95275.1 - 7.9e-34 112.3 0.4 0.00071 19.5 0.0 7.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KFX95275.1 - 3.2e-31 106.6 3.9 2.5e-06 27.5 0.1 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) SIP PF04954.8 KFX95275.1 - 0.097 13.0 0.3 0.27 11.6 0.1 1.8 1 1 0 1 1 1 0 Siderophore-interacting protein MFS_1 PF07690.11 KFX95292.1 - 5.8e-25 87.7 38.5 9.8e-25 86.9 26.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Autotransporter PF03797.14 KFX95292.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Autotransporter beta-domain Peptidase_C48 PF02902.14 KFX95294.1 - 0.00024 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_3 PF13302.1 KFX95295.1 - 2e-13 50.7 0.0 2.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX95295.1 - 5.5e-08 32.7 0.0 7.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFX95295.1 - 6.4e-07 29.3 0.0 8.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX95295.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX95295.1 - 0.016 15.2 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 KFX95296.1 - 1.9e-86 290.8 0.7 2.8e-86 290.2 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sulfatase PF00884.18 KFX95297.1 - 3.4e-77 259.6 0.0 4.2e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KFX95297.1 - 0.0001 20.8 0.0 0.0012 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 KFX95297.1 - 0.00063 19.1 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KFX95297.1 - 0.17 12.2 1.7 1.8 8.8 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 KFX95298.1 - 8.4e-112 374.0 29.3 9.6e-112 373.8 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95298.1 - 1.9e-18 66.3 33.5 7.3e-18 64.3 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rib_5-P_isom_A PF06026.9 KFX95299.1 - 2.5e-39 134.3 0.0 6.8e-34 116.6 0.0 3.1 3 0 0 3 3 3 3 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KFX95299.1 - 0.13 11.8 0.0 17 5.0 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Zn_clus PF00172.13 KFX95300.1 - 5.4e-20 71.0 24.4 1.8e-10 40.5 6.5 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX95300.1 - 8.9e-09 34.5 0.2 1.6e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alginate_lyase2 PF08787.6 KFX95301.1 - 7.7e-52 176.2 0.0 8.7e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.1 KFX95301.1 - 0.00029 20.5 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase Abhydrolase_3 PF07859.8 KFX95302.1 - 3.2e-35 121.6 0.0 4.5e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX95302.1 - 5.6e-06 25.3 1.0 2e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 KFX95302.1 - 8.5e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFX95302.1 - 3.4e-05 23.6 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX95302.1 - 0.018 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFX95302.1 - 0.041 13.0 0.6 0.07 12.3 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 KFX95302.1 - 0.058 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.3 KFX95302.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CTP_transf_1 PF01148.15 KFX95302.1 - 0.12 11.9 0.3 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family Esterase_phd PF10503.4 KFX95302.1 - 0.31 10.2 1.1 3.5 6.7 0.1 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase RTA1 PF04479.8 KFX95303.1 - 1.2e-41 142.6 8.4 1.9e-41 142.0 5.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Thioesterase PF00975.15 KFX95304.1 - 1.2e-14 55.0 0.1 2.3e-14 54.1 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFX95304.1 - 5.1e-11 42.8 0.3 5.9e-11 42.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX95304.1 - 0.00048 19.7 0.0 0.00054 19.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX95304.1 - 0.0015 18.2 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KFX95304.1 - 0.15 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.11 KFX95305.1 - 8.6e-36 123.3 79.5 1e-28 100.1 36.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95305.1 - 0.0044 15.6 38.6 0.12 10.9 10.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KFX95305.1 - 0.18 11.6 8.2 0.033 13.9 1.3 2.9 3 1 1 4 4 4 0 MFS_1 like family Fungal_trans PF04082.13 KFX95306.1 - 1.1e-15 57.2 0.3 1.8e-15 56.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 KFX95308.1 - 7.7e-08 31.4 0.0 1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF3815 PF12821.2 KFX95308.1 - 0.018 14.9 0.2 0.026 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) GMC_oxred_N PF00732.14 KFX95309.1 - 1.3e-61 208.3 0.0 2e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase COesterase PF00135.23 KFX95309.1 - 1.7e-59 201.9 0.2 2.9e-59 201.2 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family GMC_oxred_C PF05199.8 KFX95309.1 - 2e-31 109.2 0.3 4.2e-31 108.1 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_3 PF07859.8 KFX95309.1 - 1.2e-13 51.1 0.3 5.4e-13 48.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold F-box-like PF12937.2 KFX95309.1 - 2.1e-09 36.9 0.1 4.3e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX95309.1 - 3.5e-09 36.0 0.0 8e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_S9 PF00326.16 KFX95309.1 - 0.00041 19.6 0.1 0.003 16.8 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family NAD_binding_8 PF13450.1 KFX95309.1 - 0.0064 16.4 0.0 0.025 14.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HSP20 PF00011.16 KFX95310.1 - 5.2e-17 61.5 0.0 2.6e-12 46.5 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family MFS_1 PF07690.11 KFX95311.1 - 5.7e-06 25.2 31.0 3.7e-05 22.6 19.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbH PF00737.15 KFX95311.1 - 0.037 13.5 0.6 0.12 11.9 0.4 1.9 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein SNF5 PF04855.7 KFX95322.1 - 1.3e-69 234.3 0.1 2.5e-69 233.4 0.1 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 KFX95323.1 - 1.2e-10 41.3 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 TIP41 PF04176.8 KFX95324.1 - 4.1e-73 244.5 0.1 5.4e-73 244.1 0.1 1.2 1 0 0 1 1 1 1 TIP41-like family PsiB PF06290.6 KFX95324.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Pkinase PF00069.20 KFX95325.1 - 7.2e-72 241.6 0.0 8.8e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95325.1 - 1.4e-42 145.5 0.0 1.8e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX95325.1 - 2.7e-06 26.5 0.0 2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFX95325.1 - 0.00097 18.2 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFX95325.1 - 0.0046 16.3 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFX95325.1 - 0.0076 15.6 0.0 0.077 12.3 0.0 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 KFX95325.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 KFX95326.1 - 1.6e-69 232.7 2.9 2.2e-69 232.3 2.0 1.2 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.1 KFX95326.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 zf-CW PF07496.10 KFX95326.1 - 0.026 14.2 0.7 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 CW-type Zinc Finger Peptidase_S10 PF00450.17 KFX95326.1 - 0.052 12.7 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DUF2268 PF10026.4 KFX95326.1 - 0.06 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.4 KFX95326.1 - 0.073 12.7 6.8 0.032 13.8 2.1 2.3 2 1 0 2 2 2 0 SprT-like family Dicty_spore_N PF04562.7 KFX95326.1 - 0.1 12.8 1.8 0.31 11.3 0.6 2.2 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus AA_kinase PF00696.23 KFX95327.1 - 5.7e-40 137.3 2.2 8.3e-40 136.8 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFX95327.1 - 2.8e-13 49.3 2.2 1.1e-07 31.4 0.2 2.9 3 0 0 3 3 3 2 PUA domain VIT1 PF01988.14 KFX95333.1 - 2.9e-24 85.7 1.0 4.1e-24 85.2 0.7 1.2 1 0 0 1 1 1 1 VIT family PGA_cap PF09587.5 KFX95335.1 - 0.097 12.0 7.3 0.023 14.0 2.1 1.9 2 1 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap IU_nuc_hydro PF01156.14 KFX95336.1 - 1.1e-57 195.6 0.0 8.2e-46 156.6 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 KFX95337.1 - 0.00039 19.9 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain Rhomboid PF01694.17 KFX95338.1 - 9.5e-17 61.3 6.3 1.9e-16 60.3 4.4 1.4 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.5 KFX95338.1 - 1.5e-07 30.3 0.0 2.8e-05 22.8 0.0 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase PYRIN PF02758.11 KFX95338.1 - 0.32 10.7 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain AAA PF00004.24 KFX95340.1 - 9.4e-43 145.5 0.0 1.7e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX95340.1 - 2.8e-08 33.0 0.0 4.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX95340.1 - 2.5e-05 24.3 0.0 0.00014 21.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KFX95340.1 - 2.5e-05 24.0 0.1 0.00025 20.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX95340.1 - 3.6e-05 23.6 0.0 0.00053 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KFX95340.1 - 4.8e-05 23.3 0.0 0.00015 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KFX95340.1 - 6.8e-05 22.3 0.3 0.22 10.8 0.0 2.8 1 1 2 3 3 3 2 AAA domain AAA_17 PF13207.1 KFX95340.1 - 0.0001 23.1 0.0 0.00031 21.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KFX95340.1 - 0.00019 21.1 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain KaiC PF06745.8 KFX95340.1 - 0.00028 20.0 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 KFX95340.1 - 0.00046 20.3 0.5 0.0097 16.0 0.0 2.8 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KFX95340.1 - 0.00069 19.0 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KFX95340.1 - 0.0011 18.7 0.0 0.0033 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFX95340.1 - 0.0016 18.5 0.0 0.0059 16.7 0.0 2.0 1 1 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KFX95340.1 - 0.0017 17.1 0.2 0.0037 16.0 0.1 1.6 1 1 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KFX95340.1 - 0.0017 18.6 0.1 0.0055 17.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain Cytidylate_kin2 PF13189.1 KFX95340.1 - 0.0025 17.7 0.0 0.0082 16.0 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.1 KFX95340.1 - 0.0025 17.7 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFX95340.1 - 0.0025 17.3 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX95340.1 - 0.004 16.2 0.0 0.017 14.2 0.0 2.0 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KFX95340.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFX95340.1 - 0.0084 15.7 0.0 0.04 13.5 0.0 2.2 1 1 1 2 2 2 1 NACHT domain Rad17 PF03215.10 KFX95340.1 - 0.03 13.0 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Disulph_isomer PF06491.6 KFX95340.1 - 0.045 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Disulphide isomerase Sigma54_activ_2 PF14532.1 KFX95340.1 - 0.05 13.6 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFX95340.1 - 0.057 13.1 0.4 0.94 9.1 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase SKI PF01202.17 KFX95340.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase KTI12 PF08433.5 KFX95340.1 - 0.094 11.9 0.1 9.1 5.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AFG1_ATPase PF03969.11 KFX95340.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase ORC6 PF05460.8 KFX95340.1 - 0.12 11.4 2.2 0.26 10.3 1.5 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Snf7 PF03357.16 KFX95341.1 - 6.6e-33 113.4 10.5 8.3e-33 113.1 7.3 1.2 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KFX95341.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Heme_oxygenase PF01126.15 KFX95341.1 - 0.025 14.1 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 Heme oxygenase XAP5 PF04921.9 KFX95341.1 - 0.073 12.6 4.1 0.098 12.2 2.9 1.4 1 1 0 1 1 1 0 XAP5, circadian clock regulator DELLA PF12041.3 KFX95341.1 - 1.4 8.6 5.5 13 5.5 0.2 3.1 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal DUF2203 PF09969.4 KFX95341.1 - 1.6 8.9 4.2 1 9.5 0.3 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.3 KFX95341.1 - 6.8 6.7 11.3 10 6.1 1.7 2.3 1 1 0 2 2 2 0 YlqD protein Cytochrom_C PF00034.16 KFX95342.1 - 7.7e-10 39.4 0.0 1.2e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KFX95342.1 - 4.8e-09 36.2 0.5 3.8e-08 33.3 0.3 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KFX95342.1 - 0.0002 20.8 0.2 0.0015 17.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Zn_clus PF00172.13 KFX95357.1 - 9.4e-07 28.6 8.5 1.9e-06 27.6 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 KFX95362.1 - 1.1e-07 30.9 0.0 1.3e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V PaaX_C PF08223.6 KFX95362.1 - 0.035 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain UDPGP PF01704.13 KFX95369.1 - 9.9e-52 175.8 0.0 1.5e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase adh_short PF00106.20 KFX95370.1 - 1.1e-08 35.1 0.0 1.2e-08 35.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX95370.1 - 7.3e-06 25.9 0.0 8.1e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX95370.1 - 0.029 14.0 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 KR domain Condensation PF00668.15 KFX95387.1 - 3.3e-37 127.9 0.0 5.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KFX95387.1 - 1.3e-12 47.7 0.0 2.3e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding PF00501.23 KFX95387.1 - 0.0041 15.5 0.0 0.0073 14.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme LIM PF00412.17 KFX95392.1 - 1.3e-14 54.0 19.4 2.5e-09 37.0 2.7 2.3 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 KFX95392.1 - 0.0075 16.1 17.7 0.13 12.2 1.0 4.2 4 0 0 4 4 4 2 Zinc ribbon domain DZR PF12773.2 KFX95392.1 - 0.019 14.7 18.2 25 4.7 0.1 4.3 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_CIII PF02085.11 KFX95392.1 - 0.9 9.6 13.4 19 5.3 6.5 2.5 1 1 1 2 2 2 0 Class III cytochrome C family TF_Zn_Ribbon PF08271.7 KFX95392.1 - 1.4 8.3 17.2 1.1 8.5 0.6 4.3 4 1 1 5 5 5 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 KFX95392.1 - 3.9 7.0 16.1 0.67 9.5 0.0 5.0 5 1 0 5 5 5 0 zinc-ribbon domain Cys_Met_Meta_PP PF01053.15 KFX95403.1 - 3e-148 493.2 0.0 3.4e-148 493.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFX95403.1 - 1.2e-11 44.1 0.1 2.2e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFX95403.1 - 2.9e-11 43.0 0.6 5.3e-11 42.1 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KFX95403.1 - 5.9e-07 28.5 0.1 1.4e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFX95403.1 - 0.00012 21.2 0.0 0.0003 20.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KFX95403.1 - 0.002 16.8 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein SelA PF03841.8 KFX95403.1 - 0.0089 14.8 0.1 0.028 13.1 0.1 1.7 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase Met_gamma_lyase PF06838.6 KFX95403.1 - 0.01 14.1 0.2 0.015 13.6 0.1 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase Thioredoxin_7 PF13899.1 KFX95406.1 - 7.6e-15 54.6 0.1 1.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KFX95406.1 - 6e-12 44.8 0.0 1.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KFX95406.1 - 1.4e-06 28.2 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 KFX95406.1 - 0.0037 16.9 0.1 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 KFX95406.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Ecm29 PF13001.2 KFX95407.1 - 8.5e-136 453.3 0.0 1.8e-135 452.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 KFX95407.1 - 1.2e-08 34.3 4.0 6.1 7.2 0.0 8.1 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 KFX95407.1 - 2.3e-07 31.1 7.4 0.25 11.8 0.1 8.9 9 1 1 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.1 KFX95407.1 - 3.7e-07 30.3 16.0 0.11 12.8 0.0 9.7 8 2 2 10 10 10 2 HEAT repeats Vac14_Fab1_bd PF12755.2 KFX95407.1 - 0.0014 19.0 0.1 0.32 11.3 0.0 4.6 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region MBOAT_2 PF13813.1 KFX95408.1 - 2.8e-14 52.9 3.7 2.8e-14 52.9 2.6 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family hDGE_amylase PF14701.1 KFX95409.1 - 2.2e-178 593.5 0.0 2.8e-178 593.1 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KFX95409.1 - 7.7e-114 380.2 0.0 1.1e-113 379.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KFX95409.1 - 5.2e-84 281.4 0.0 7.9e-84 280.8 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KFX95409.1 - 2.4e-25 88.1 0.0 7e-25 86.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KFX95409.1 - 7e-07 28.9 0.0 0.00047 19.6 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DAHP_synth_1 PF00793.15 KFX95411.1 - 6.4e-99 330.0 0.0 8.4e-99 329.6 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Autophagy_act_C PF03987.10 KFX95412.1 - 7.7e-13 48.4 0.3 1.3e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Cytochrom_C1 PF02167.10 KFX95413.1 - 2.9e-82 275.5 0.0 3.7e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KFX95413.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1515 PF07439.6 KFX95413.1 - 0.11 12.2 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HhH-GPD PF00730.20 KFX95414.1 - 0.00036 20.7 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PBD PF00786.23 KFX95414.1 - 0.048 14.0 0.6 0.26 11.7 0.1 2.6 2 0 0 2 2 2 0 P21-Rho-binding domain AIG2_2 PF13772.1 KFX95415.1 - 8.9e-06 25.7 0.2 5.5e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 AIG2-like family Hormone_3 PF00159.13 KFX95415.1 - 0.086 12.8 0.3 0.086 12.8 0.2 2.1 2 0 0 2 2 2 0 Pancreatic hormone peptide FCH PF00611.18 KFX95416.1 - 0.03 14.5 1.0 0.11 12.7 0.7 1.9 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain SLX9 PF15341.1 KFX95417.1 - 1.7e-36 125.3 3.5 2.3e-36 124.8 2.4 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 AP_endonuc_2 PF01261.19 KFX95418.1 - 1.9e-26 92.6 0.0 2.6e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short PF00106.20 KFX95420.1 - 3.7e-22 79.0 0.2 5.8e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX95420.1 - 1e-15 58.2 0.0 1.2e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFX95420.1 - 0.00026 20.2 0.0 0.04 13.0 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFX95420.1 - 0.012 15.5 0.2 0.042 13.8 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 KFX95420.1 - 0.054 12.9 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cation_efflux PF01545.16 KFX95421.1 - 2.4e-31 108.8 7.4 3.1e-31 108.5 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family Peptidase_C48 PF02902.14 KFX95422.1 - 4.4e-16 59.1 0.1 1.9e-15 57.0 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain KH_1 PF00013.24 KFX95423.1 - 0.00022 20.7 2.1 0.00022 20.7 1.5 1.7 2 0 0 2 2 2 1 KH domain MDM31_MDM32 PF08118.6 KFX95424.1 - 3.3e-192 639.4 1.1 3.9e-192 639.1 0.8 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 KFX95424.1 - 0.049 13.0 0.2 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 TraH_2 Pkinase PF00069.20 KFX95425.1 - 6e-75 251.7 0.0 9.8e-75 251.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95425.1 - 8.1e-37 126.6 0.0 1.3e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFX95425.1 - 3.8e-17 62.1 0.1 8.3e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFX95425.1 - 1.1e-08 34.4 0.0 4.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KFX95425.1 - 0.0047 15.7 0.2 0.01 14.6 0.1 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KFX95425.1 - 0.019 14.0 0.1 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX95425.1 - 0.02 14.5 0.1 0.077 12.7 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFX95425.1 - 0.12 11.6 0.1 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HCNGP PF07818.8 KFX95426.1 - 2.6e-34 117.1 0.6 4.2e-34 116.4 0.4 1.3 1 0 0 1 1 1 1 HCNGP-like protein GRP PF07172.6 KFX95433.1 - 0.017 15.6 7.6 0.017 15.6 5.3 3.9 3 1 0 3 3 3 0 Glycine rich protein family CYSTM PF12734.2 KFX95434.1 - 1.3 9.1 5.5 2.2 8.4 3.8 1.4 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance EMG1 PF03587.9 KFX95435.1 - 8.6e-78 260.2 0.0 1e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase APG9 PF04109.11 KFX95437.1 - 1.1e-168 560.9 1.2 1.5e-168 560.4 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 W2 PF02020.13 KFX95438.1 - 9.5e-18 63.9 1.8 3.1e-17 62.3 1.3 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KFX95438.1 - 2.1e-07 30.1 13.6 0.04 13.4 0.4 4.4 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KFX95438.1 - 2.9e-06 26.7 0.0 5.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 KFX95438.1 - 0.0066 15.9 9.7 0.34 10.5 0.3 3.4 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KFX95438.1 - 0.0071 16.4 0.0 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 KFX95438.1 - 0.33 9.4 3.5 1.4 7.4 0.3 2.1 1 1 1 2 2 2 0 L-fucokinase Mito_carr PF00153.22 KFX95439.1 - 4.8e-56 186.4 2.8 2.3e-22 78.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2783 PF10932.3 KFX95441.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) EI24 PF07264.6 KFX95442.1 - 0.00073 19.0 3.7 0.00073 19.0 2.6 2.4 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Yippee-Mis18 PF03226.9 KFX95445.1 - 1e-21 76.7 0.0 1.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KFX95445.1 - 0.055 13.3 0.1 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Aldedh PF00171.17 KFX95447.1 - 1.2e-76 257.9 0.0 1.4e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lyase_1 PF00206.15 KFX95448.1 - 1.4e-85 287.2 0.0 1.9e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KFX95448.1 - 1.9e-24 85.5 0.2 3.8e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FMN_red PF03358.10 KFX95449.1 - 3.9e-30 104.3 0.0 5e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFX95449.1 - 9.6e-11 41.5 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MRP-S28 PF10213.4 KFX95451.1 - 7.1e-44 148.9 0.1 1.4e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Rot1 PF10681.4 KFX95457.1 - 1e-27 96.8 1.6 1.2e-27 96.6 1.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal PALP PF00291.20 KFX95459.1 - 3.9e-57 193.8 0.1 4.6e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Chitin_bind_3 PF03067.10 KFX95460.1 - 3.4e-11 43.7 0.0 4.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain p450 PF00067.17 KFX95463.1 - 1e-59 202.3 0.0 1.3e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MadL PF03817.8 KFX95463.1 - 0.023 14.5 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Malonate transporter MadL subunit Rab5ip PF07019.7 KFX95463.1 - 0.033 14.3 0.6 0.091 12.8 0.4 1.7 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) PUF PF00806.14 KFX95464.1 - 9e-57 185.4 11.7 7.2e-08 31.4 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CCDC-167 PF15188.1 KFX95464.1 - 0.79 9.7 6.8 2 8.4 4.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 RNA_pol_Rpb2_6 PF00562.23 KFX95466.1 - 2e-115 385.6 0.1 3.7e-115 384.7 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFX95466.1 - 5.7e-53 178.8 0.1 8.7e-53 178.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFX95466.1 - 2e-29 102.3 0.0 7.5e-29 100.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KFX95466.1 - 8.9e-28 96.3 0.4 3e-27 94.6 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 KFX95466.1 - 1.5e-19 69.4 0.0 2.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KFX95466.1 - 1.6e-19 69.4 0.0 4.5e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KFX95466.1 - 6.1e-12 45.3 0.2 1.4e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 KFX95466.1 - 0.019 13.3 0.1 0.032 12.5 0.1 1.2 1 0 0 1 1 1 0 Baculovirus Y142 protein Sugar_tr PF00083.19 KFX95467.1 - 1e-87 294.6 28.4 1.3e-87 294.2 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95467.1 - 3e-14 52.5 47.9 2e-09 36.6 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KFX95468.1 - 5.8e-19 68.8 0.0 7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95468.1 - 2.7e-06 27.2 0.0 3.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sua5_yciO_yrdC PF01300.13 KFX95469.1 - 8e-16 57.7 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination LysM PF01476.15 KFX95471.1 - 1.5e-24 85.6 0.1 0.00049 19.9 0.0 6.1 6 0 0 6 6 6 5 LysM domain Glyco_hydro_18 PF00704.23 KFX95472.1 - 6.3e-76 256.0 0.1 7.5e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX95472.1 - 2.1e-07 30.7 9.7 2.1e-07 30.7 6.7 2.7 2 1 0 2 2 2 1 Chitin recognition protein DUF2622 PF11080.3 KFX95472.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) Lipase_GDSL_2 PF13472.1 KFX95473.1 - 1.8e-11 44.4 0.1 6.1e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX95473.1 - 4.8e-08 33.1 0.5 1.8e-06 27.9 0.1 2.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase MCR_alpha PF02249.12 KFX95473.1 - 0.019 14.9 0.5 2.8 7.9 0.1 2.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Aminotran_5 PF00266.14 KFX95475.1 - 0.00016 20.5 0.0 0.00018 20.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V FGGY_C PF02782.11 KFX95478.1 - 3e-69 232.6 2.7 5.3e-69 231.8 1.9 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFX95478.1 - 8.1e-66 221.8 0.0 1.1e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_hydro_7 PF00840.15 KFX95479.1 - 3.4e-117 391.4 11.1 4.3e-117 391.1 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3919 PF13057.1 KFX95479.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Melibiase PF02065.13 KFX95480.1 - 1.5e-25 89.7 2.1 2e-19 69.5 0.0 3.8 1 1 1 2 2 2 2 Melibiase Raffinose_syn PF05691.7 KFX95480.1 - 0.015 12.8 0.1 0.021 12.3 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_26 PF02156.10 KFX95481.1 - 3.7e-77 259.8 2.7 4.3e-77 259.6 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Ank_2 PF12796.2 KFX95482.1 - 8.5e-56 186.2 12.8 7.5e-18 64.6 0.1 4.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95482.1 - 1.6e-28 97.0 5.4 2.5e-05 23.8 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 KFX95482.1 - 5.2e-28 96.9 0.4 8.9e-09 35.6 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX95482.1 - 5.3e-28 96.4 5.0 5e-06 26.5 0.0 6.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95482.1 - 1.4e-26 89.9 1.9 0.00014 21.7 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat adh_short PF00106.20 KFX95483.1 - 1.9e-22 79.9 0.1 2.5e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX95483.1 - 1.3e-09 37.9 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KFX95483.1 - 2.8e-05 23.1 0.0 3.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KFX95483.1 - 3.3e-05 23.4 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFX95483.1 - 0.0002 21.1 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 KFX95483.1 - 0.0033 16.8 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Phytase PF02333.10 KFX95485.1 - 2.9e-59 200.6 2.6 4.3e-58 196.8 0.0 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.8 KFX95485.1 - 5.4e-06 26.4 32.7 0.0019 18.3 7.0 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 KFX95485.1 - 0.00067 19.5 21.4 0.0029 17.5 3.1 2.4 2 0 0 2 2 2 2 EGF-like domain Plasmod_Pvs28 PF06247.6 KFX95485.1 - 0.086 12.4 13.5 0.15 11.6 9.4 1.3 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 hEGF PF12661.2 KFX95485.1 - 0.48 10.6 13.2 0.86 9.8 2.2 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF Abhydrolase_3 PF07859.8 KFX95487.1 - 1.1e-30 106.8 0.0 2.9e-30 105.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioredoxin PF00085.15 KFX95487.1 - 2e-20 72.4 0.0 4.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Acetyltransf_4 PF13420.1 KFX95487.1 - 2.4e-09 37.3 0.1 0.055 13.4 0.0 3.8 5 0 0 5 5 3 3 Acetyltransferase (GNAT) domain DLH PF01738.13 KFX95487.1 - 1.7e-08 34.0 0.3 5.3e-07 29.1 0.1 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Thioredoxin_2 PF13098.1 KFX95487.1 - 2.7e-05 24.3 0.1 0.00026 21.1 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFX95487.1 - 0.0019 18.2 0.2 0.0061 16.6 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like Acetyltransf_1 PF00583.19 KFX95487.1 - 0.0021 18.0 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family BAAT_C PF08840.6 KFX95487.1 - 0.0041 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KFX95487.1 - 0.0075 15.5 0.1 0.096 11.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Redoxin PF08534.5 KFX95487.1 - 0.012 15.1 0.0 0.036 13.5 0.0 1.8 1 0 0 1 1 1 0 Redoxin Acetyltransf_7 PF13508.1 KFX95487.1 - 0.023 14.8 0.0 0.066 13.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX95487.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AhpC-TSA PF00578.16 KFX95487.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Acetyltransf_10 PF13673.1 KFX95487.1 - 0.078 13.0 0.0 0.27 11.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain COesterase PF00135.23 KFX95487.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family tRNA-synt_1 PF00133.17 KFX95488.1 - 9.6e-217 720.7 0.0 1.5e-216 720.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFX95488.1 - 1.5e-27 96.2 0.0 3.4e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFX95488.1 - 1.3e-19 70.1 0.1 5.4e-07 28.6 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) But2 PF09792.4 KFX95489.1 - 7e-56 187.9 2.1 1.3e-55 187.0 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Nop14 PF04147.7 KFX95490.1 - 0.0017 16.4 13.6 0.0017 16.3 9.4 1.0 1 0 0 1 1 1 1 Nop14-like family Paf1 PF03985.8 KFX95490.1 - 0.56 8.8 19.3 0.75 8.4 13.4 1.1 1 0 0 1 1 1 0 Paf1 Tom37_C PF11801.3 KFX95490.1 - 0.92 9.3 4.0 1.4 8.7 2.8 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 KFX95490.1 - 3.4 5.5 15.4 4.3 5.2 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein GFO_IDH_MocA PF01408.17 KFX95494.1 - 3.8e-23 82.2 0.1 1.1e-22 80.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX95494.1 - 3.4e-05 23.6 0.0 9.2e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KFX95494.1 - 0.00029 21.1 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 KFX95494.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain DUF641 PF04859.7 KFX95496.1 - 0.0068 16.1 1.0 0.0068 16.1 0.7 5.9 3 2 3 6 6 6 1 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 KFX95496.1 - 0.071 13.0 9.7 3.6 7.5 0.2 5.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 KFX95496.1 - 0.13 10.9 38.7 0.37 9.4 3.1 4.9 3 1 3 6 6 6 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KFX95496.1 - 0.83 9.7 23.5 0.2 11.8 1.5 5.3 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family Filament PF00038.16 KFX95496.1 - 4.7 6.5 50.2 0.016 14.7 15.6 4.6 3 2 2 5 5 5 0 Intermediate filament protein LMBR1 PF04791.11 KFX95499.1 - 1.1 7.7 3.7 1.4 7.4 2.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 KFX95499.1 - 2 6.9 6.7 2.6 6.5 4.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IncA PF04156.9 KFX95499.1 - 3.7 7.0 13.6 4.3 6.9 9.0 1.3 1 1 0 1 1 1 0 IncA protein Polyketide_cyc PF03364.15 KFX95500.1 - 1.1e-23 83.6 0.0 3.2e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KFX95500.1 - 0.0047 17.1 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.7 KFX95501.1 - 2.8e-15 56.6 0.0 7.3e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX95501.1 - 4.4e-12 46.3 0.0 8.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX95501.1 - 8.4e-12 45.0 0.0 1.3e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX95501.1 - 1.3e-11 44.7 0.0 2.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX95501.1 - 4e-09 36.2 0.0 7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX95501.1 - 3e-08 33.0 0.0 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFX95501.1 - 1.1e-07 32.4 0.0 2.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX95501.1 - 6e-05 23.0 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX95501.1 - 0.00057 19.2 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KFX95501.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF3419 PF11899.3 KFX95501.1 - 0.0038 16.0 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) PrmA PF06325.8 KFX95501.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.12 KFX95501.1 - 0.013 14.5 0.0 0.42 9.5 0.0 2.2 1 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 KFX95501.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.8 1 1 1 2 2 2 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 KFX95501.1 - 0.046 14.5 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KFX95501.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Nucleoplasmin PF03066.10 KFX95502.1 - 0.4 10.1 0.1 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF3812 PF12757.2 KFX95503.1 - 2.3e-28 98.7 8.8 2.3e-28 98.7 6.1 4.2 4 1 1 5 5 5 2 Protein of unknown function (DUF3812) DUF2743 PF10899.3 KFX95503.1 - 0.11 11.9 6.8 0.22 10.8 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) F-box PF00646.28 KFX95506.1 - 6e-05 22.5 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain HTH_26 PF13443.1 KFX95506.1 - 0.064 13.4 0.0 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain APH PF01636.18 KFX95507.1 - 5.5e-13 49.1 0.0 8.6e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX95507.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFX95507.1 - 0.023 13.8 0.0 0.75 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 KFX95507.1 - 0.035 12.7 0.0 0.2 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF4190 PF13828.1 KFX95508.1 - 0.018 14.5 0.9 0.029 13.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Serglycin PF04360.7 KFX95508.1 - 0.74 9.5 4.3 1.1 8.9 3.0 1.3 1 0 0 1 1 1 0 Serglycin SPRY PF00622.23 KFX95510.1 - 0.00023 21.2 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain DUF3645 PF12359.3 KFX95510.1 - 0.0046 16.0 19.3 0.8 8.8 0.7 4.4 4 0 0 4 4 4 3 Protein of unknown function (DUF3645) Ribosomal_L6 PF00347.18 KFX95511.1 - 1.6e-27 95.7 8.0 1.2e-14 54.4 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ferric_reduct PF01794.14 KFX95527.1 - 5.6e-14 52.2 2.3 5.6e-14 52.2 1.6 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component p450 PF00067.17 KFX95530.1 - 4.6e-14 51.7 0.0 3.8e-13 48.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFX95532.1 - 1.2e-42 145.9 39.2 1.2e-42 145.9 27.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95532.1 - 2.7e-08 32.8 25.6 8.6e-08 31.1 17.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KFX95532.1 - 0.19 9.8 9.9 0.24 9.4 5.4 2.2 1 1 0 1 1 1 0 Transmembrane secretion effector ATP-synt_8 PF00895.15 KFX95532.1 - 7.7 6.8 7.6 16 5.8 0.4 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 CAP_N PF01213.14 KFX95533.1 - 0.39 9.9 1.7 0.51 9.5 1.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FlxA PF14282.1 KFX95534.1 - 0.00077 19.3 0.6 0.0026 17.6 0.4 1.9 1 0 0 1 1 1 1 FlxA-like protein Enkurin PF13864.1 KFX95534.1 - 0.23 11.6 0.8 0.53 10.5 0.6 1.5 1 0 0 1 1 1 0 Calmodulin-binding Thr_synth_N PF14821.1 KFX95535.1 - 8e-29 99.4 0.0 1.9e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KFX95535.1 - 1.7e-21 76.7 0.0 2.1e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Colipase-like PF15083.1 KFX95536.1 - 0.012 15.5 2.3 0.012 15.5 1.6 3.8 1 1 3 4 4 4 0 Colipase-like DUF866 PF05907.8 KFX95538.1 - 2.8e-42 143.9 0.2 4.4e-42 143.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 KFX95538.1 - 1.1e-18 66.5 0.2 1.5e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain PRMT5 PF05185.11 KFX95539.1 - 6.8e-172 572.3 0.0 8.5e-172 572.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 KFX95540.1 - 5.4e-27 93.8 0.0 1.3e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX95540.1 - 3.8e-23 81.4 0.1 9.9e-23 80.1 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX95540.1 - 7.6e-12 44.9 0.0 2.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX95540.1 - 3e-07 30.0 0.5 1.4e-06 27.8 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX95540.1 - 1.7e-05 24.9 0.0 5.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KFX95540.1 - 0.00024 20.6 0.1 0.00066 19.1 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 KFX95540.1 - 0.0024 17.7 0.0 0.95 9.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KFX95540.1 - 0.0046 16.7 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 KFX95540.1 - 0.028 13.3 0.0 0.07 12.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 KFX95540.1 - 0.13 11.5 0.5 0.47 9.6 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein Aconitase PF00330.15 KFX95550.1 - 6e-158 526.1 0.0 1.5e-157 524.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Pkinase PF00069.20 KFX95553.1 - 4.6e-11 42.3 0.0 7.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KFX95553.1 - 2e-08 33.6 3.7 0.28 11.3 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Pkinase_Tyr PF07714.12 KFX95553.1 - 9.5e-08 31.4 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 KFX95553.1 - 4.2e-05 23.7 0.6 0.0069 16.6 0.1 3.4 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KFX95553.1 - 7.3e-05 23.1 0.2 0.92 10.0 0.1 3.3 2 0 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.15 KFX95553.1 - 0.0073 14.6 0.4 0.23 9.7 0.1 2.1 1 1 1 2 2 2 1 Adaptin N terminal region Kinase-like PF14531.1 KFX95553.1 - 0.046 12.6 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CIAPIN1 PF05093.8 KFX95554.1 - 6.5e-34 116.0 2.1 1e-33 115.4 1.5 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-CSL PF05207.8 KFX95554.1 - 0.51 9.8 2.8 1.6 8.2 1.9 1.8 1 1 0 1 1 1 0 CSL zinc finger APH PF01636.18 KFX95555.1 - 5.9e-14 52.3 0.0 1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KFX95556.1 - 1.7e-08 34.5 0.0 0.00013 21.7 0.0 2.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX95556.1 - 0.0036 16.9 0.1 0.0099 15.4 0.0 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase HEAT_2 PF13646.1 KFX95556.1 - 0.084 13.1 0.1 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats GMC_oxred_C PF05199.8 KFX95557.1 - 1.4e-30 106.5 0.0 2.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KFX95557.1 - 8.7e-26 90.7 0.0 7.6e-25 87.6 0.0 2.3 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KFX95557.1 - 0.00023 21.2 0.1 0.077 13.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX95557.1 - 0.0012 18.7 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX95557.1 - 0.0015 17.4 1.4 1.2 7.9 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX95557.1 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KFX95557.1 - 0.048 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX95557.1 - 0.095 11.5 1.2 0.36 9.6 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KFX95557.1 - 0.1 11.4 0.4 0.16 10.8 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CFEM PF05730.6 KFX95558.1 - 1.8e-14 53.2 9.2 3.4e-14 52.4 6.4 1.4 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.12 KFX95559.1 - 4.7e-11 41.9 3.1 5.4e-10 38.4 2.2 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 Pkinase PF00069.20 KFX95560.1 - 1.1e-27 96.8 0.0 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95560.1 - 6.5e-20 71.2 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HABP4_PAI-RBP1 PF04774.10 KFX95561.1 - 2 8.9 10.2 0.12 12.8 2.7 2.3 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family adh_short PF00106.20 KFX95562.1 - 1.7e-26 93.1 0.8 2.2e-26 92.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX95562.1 - 1.2e-22 80.8 0.1 1.4e-22 80.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX95562.1 - 2.3e-13 50.1 0.2 3.2e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX95562.1 - 0.0028 17.1 0.2 0.0095 15.3 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX95562.1 - 0.053 12.4 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFX95562.1 - 0.12 11.2 0.1 0.93 8.3 0.1 2.3 1 1 1 2 2 2 0 Male sterility protein F-box-like PF12937.2 KFX95563.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX95563.1 - 0.00061 19.3 0.3 0.0023 17.5 0.2 2.0 1 0 0 1 1 1 1 F-box domain Peptidase_S10 PF00450.17 KFX95564.1 - 8.3e-112 374.3 0.0 1e-111 374.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFX95564.1 - 0.0018 18.2 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNA_Me_trans PF04252.8 KFX95565.1 - 2.5e-47 160.8 0.0 3e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.12 KFX95566.1 - 1.7e-20 72.7 0.0 2.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.8 KFX95567.1 - 6.5e-123 410.1 0.0 7.4e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 KFX95568.1 - 2.4e-146 487.5 11.9 2.7e-146 487.3 8.3 1.0 1 0 0 1 1 1 1 ICE2 PB1 PF00564.19 KFX95570.1 - 9.2e-07 28.4 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 PB1 domain PX PF00787.19 KFX95572.1 - 6.9e-15 54.8 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.23 KFX95572.1 - 1.1e-11 43.9 0.0 2.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX95572.1 - 2.1e-07 30.3 0.1 9.5e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KFX95572.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain DUF4407 PF14362.1 KFX95572.1 - 0.54 9.1 10.6 0.73 8.7 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIH1 PF08190.7 KFX95572.1 - 0.92 8.8 7.4 1.4 8.3 5.1 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CPSF100_C PF13299.1 KFX95572.1 - 4.9 7.3 7.4 7.9 6.6 5.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4175 PF13779.1 KFX95572.1 - 7 4.2 25.8 8.9 3.8 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SNF2_N PF00176.18 KFX95588.1 - 9e-60 201.9 0.0 5e-59 199.5 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX95588.1 - 1.1e-11 44.4 0.3 1.2e-10 41.1 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFX95588.1 - 2.5e-09 36.3 0.1 8e-08 31.4 0.0 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFX95588.1 - 0.00051 19.9 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.24 KFX95588.1 - 0.0029 17.2 21.8 0.0041 16.7 6.4 3.3 1 1 1 2 2 2 1 PHD-finger CortBP2 PF09727.4 KFX95588.1 - 0.042 13.3 1.8 0.29 10.6 0.1 2.4 2 0 0 2 2 2 0 Cortactin-binding protein-2 zf-RING_2 PF13639.1 KFX95588.1 - 0.48 10.3 17.6 0.7 9.7 3.2 2.6 2 0 0 2 2 2 0 Ring finger domain Clr2 PF10383.4 KFX95589.1 - 2e-20 73.1 0.1 3.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ThiF PF00899.16 KFX95590.1 - 9.2e-11 41.7 0.0 2.3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 ThiF family Fungal_trans PF04082.13 KFX95591.1 - 1e-23 83.5 0.0 1.7e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95591.1 - 3.4e-06 26.8 15.4 6e-06 26.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_5 PF14634.1 KFX95592.1 - 7.3e-08 32.0 6.6 1.2e-07 31.3 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFX95592.1 - 9.3e-05 22.1 6.1 0.00016 21.4 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX95592.1 - 0.00011 22.0 7.0 0.00021 21.2 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX95592.1 - 0.00039 20.0 7.0 0.0007 19.2 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX95592.1 - 0.0011 18.5 7.2 0.0021 17.6 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.11 KFX95592.1 - 0.0042 15.7 0.2 0.0048 15.5 0.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein zf-rbx1 PF12678.2 KFX95592.1 - 0.018 15.1 2.1 0.034 14.2 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFX95592.1 - 0.022 14.4 1.2 0.072 12.8 0.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX95592.1 - 0.023 14.5 5.5 0.047 13.5 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CENP-K PF11802.3 KFX95592.1 - 0.041 13.1 3.6 0.061 12.5 2.5 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DNA_ligase_ZBD PF03119.11 KFX95592.1 - 0.052 13.2 2.8 0.38 10.5 0.1 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_6 PF14835.1 KFX95592.1 - 0.058 13.1 2.9 0.12 12.2 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFX95592.1 - 0.063 13.1 0.7 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M4 PF01447.13 KFX95592.1 - 0.065 13.3 1.4 0.11 12.5 1.0 1.4 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain zf-MIZ PF02891.15 KFX95592.1 - 0.083 12.4 4.5 0.15 11.5 3.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Fmp27_WPPW PF10359.4 KFX95592.1 - 0.28 9.5 7.9 0.37 9.1 5.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain zf-RING_4 PF14570.1 KFX95592.1 - 0.29 10.7 2.6 0.59 9.7 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RNA_POL_M_15KD PF02150.11 KFX95592.1 - 0.59 9.8 7.4 0.76 9.5 1.6 2.8 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit DUF1272 PF06906.6 KFX95592.1 - 1.1 9.1 7.2 2.7 7.9 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) DUF342 PF03961.8 KFX95592.1 - 1.4 7.2 5.0 1.9 6.7 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KFX95592.1 - 1.4 8.4 5.5 2.1 7.8 3.8 1.2 1 0 0 1 1 1 0 IncA protein C1_4 PF07975.7 KFX95592.1 - 2.3 8.2 5.3 9.5 6.3 1.9 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS91 PF14319.1 KFX95592.1 - 4.6 6.7 8.5 9.5 5.7 1.6 3.0 1 1 2 3 3 3 0 Transposase zinc-binding domain GDA1_CD39 PF01150.12 KFX95593.1 - 5.3e-108 361.3 0.0 7.4e-108 360.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.7 KFX95594.1 - 1.7e-50 171.3 0.0 2e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Nup_retrotrp_bd PF10599.4 KFX95594.1 - 1.1 9.8 5.4 0.72 10.5 2.0 1.8 1 1 1 2 2 2 0 Retro-transposon transporting motif NUDIX PF00293.23 KFX95595.1 - 0.00018 21.1 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 KFX95596.1 - 1.5e-33 115.9 0.0 2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 KFX95597.1 - 1.1e-90 304.0 0.0 1.7e-90 303.4 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 KFX95598.1 - 1.8e-13 50.0 0.0 5.5e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.16 KFX95599.1 - 1.7e-26 93.1 0.0 6.6e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Sec7 PF01369.15 KFX95600.1 - 3.4e-59 199.7 0.0 5.4e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFX95600.1 - 2.8e-19 69.1 0.3 2e-11 43.6 0.2 3.0 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Abhydrolase_6 PF12697.2 KFX95601.1 - 7.4e-12 45.6 0.4 9e-12 45.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95601.1 - 1.1e-06 28.4 0.1 1.3e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KFX95601.1 - 0.033 13.6 0.2 0.065 12.7 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase Fungal_trans PF04082.13 KFX95602.1 - 2.6e-27 95.3 0.0 3.1e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KFX95618.1 - 2.3e-14 52.8 17.8 1.7e-07 31.1 1.5 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFX95618.1 - 1.9e-11 43.5 22.9 0.0015 18.7 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX95618.1 - 2.5e-07 30.5 20.3 0.0099 16.1 3.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFX95618.1 - 0.0074 16.1 10.5 0.97 9.4 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX95618.1 - 0.0098 16.0 11.2 0.12 12.5 2.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KFX95618.1 - 0.049 13.7 11.6 0.2 11.8 4.8 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rpr2 PF04032.11 KFX95618.1 - 0.066 13.1 0.8 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CHCC PF10276.4 KFX95618.1 - 0.09 12.6 6.7 0.25 11.1 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.1 KFX95618.1 - 0.86 9.3 6.8 0.067 12.8 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 KFX95618.1 - 0.87 9.6 7.7 6 6.9 0.1 3.2 2 1 1 3 3 3 0 zinc-finger zf-CHY PF05495.7 KFX95618.1 - 1.4 9.1 8.4 2.8 8.1 5.8 1.5 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.2 KFX95618.1 - 1.4 8.7 6.0 16 5.4 4.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon GAGA PF09237.6 KFX95618.1 - 5.1 6.7 8.4 5.1 6.7 0.6 3.2 1 1 2 3 3 3 0 GAGA factor Zn-ribbon_8 PF09723.5 KFX95618.1 - 6.4 6.8 8.5 35 4.4 2.0 2.9 1 1 2 3 3 3 0 Zinc ribbon domain EF-hand_1 PF00036.27 KFX95620.1 - 8.4e-19 65.3 7.7 1.6e-08 33.2 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFX95620.1 - 4.1e-18 65.2 1.2 2.4e-10 40.4 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFX95620.1 - 5.7e-16 57.8 8.5 3.4e-08 32.9 0.3 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KFX95620.1 - 1.7e-15 55.4 6.9 3e-07 29.7 0.3 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KFX95620.1 - 4.1e-07 29.0 9.4 0.00014 21.0 0.1 3.2 3 1 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 KFX95620.1 - 0.0001 21.9 0.2 0.0008 19.1 0.0 2.3 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFX95620.1 - 0.0011 18.8 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Methyltransf_3 PF01596.12 KFX95620.1 - 0.068 12.2 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase Caleosin PF05042.8 KFX95620.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Caleosin related protein DUF3911 PF13050.1 KFX95620.1 - 0.16 12.0 0.2 24 5.1 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3911) GDI PF00996.13 KFX95625.1 - 6.4e-40 136.7 0.0 8.9e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Ferric_reduct PF01794.14 KFX95626.1 - 6.5e-17 61.7 6.1 6.5e-17 61.7 4.2 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX95626.1 - 8.9e-16 58.1 0.0 6.6e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX95626.1 - 2.9e-13 49.5 0.0 5.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFX95626.1 - 0.0013 19.2 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 KFX95626.1 - 0.64 10.1 8.6 0.46 10.6 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) PDR_CDR PF06422.7 KFX95627.1 - 0.00083 18.9 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 CDR ABC transporter DUF4562 PF15123.1 KFX95627.1 - 0.0036 17.1 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) VirB8 PF04335.8 KFX95627.1 - 0.0097 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 VirB8 protein Sec63 PF02889.11 KFX95629.1 - 1e-46 159.6 0.0 1.4e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KFX95629.1 - 8e-25 87.2 0.0 1.6e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX95629.1 - 1.5e-08 34.4 0.0 3.3e-07 30.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX95629.1 - 3.3e-07 30.3 0.0 7.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdd1 PF11731.3 KFX95629.1 - 0.0066 16.3 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Pathogenicity locus AAA_30 PF13604.1 KFX95629.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KFX95629.1 - 0.011 15.0 0.1 0.049 12.9 0.0 2.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KFX95629.1 - 0.082 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.1 KFX95629.1 - 0.14 12.3 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Nuc_sug_transp PF04142.10 KFX95630.1 - 9.9e-80 267.1 10.4 9.9e-80 267.1 7.2 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KFX95630.1 - 1.7e-09 37.0 14.6 2.3e-08 33.3 10.1 2.1 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFX95630.1 - 8.7e-08 31.9 22.3 0.00035 20.2 0.6 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KFX95630.1 - 1.6e-07 31.4 0.9 1.6e-07 31.4 0.6 2.4 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KFX95630.1 - 6.9e-05 22.8 24.4 9.9e-05 22.3 2.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF454 PF04304.8 KFX95630.1 - 0.28 11.2 8.5 1.1 9.3 2.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) FUSC_2 PF13515.1 KFX95630.1 - 0.98 9.3 10.6 0.12 12.2 3.4 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Cyclin_N PF00134.18 KFX95631.1 - 3.6e-13 49.1 0.0 7.8e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFX95631.1 - 1.2e-10 42.0 0.2 1.3e-09 38.6 0.1 2.3 1 1 0 1 1 1 1 Cyclin WD40 PF00400.27 KFX95632.1 - 4.2e-72 235.6 17.2 1.2e-11 44.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX95632.1 - 4.3e-11 41.6 0.6 8.6e-05 20.8 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX95632.1 - 0.012 14.3 0.2 2.4 6.7 0.0 2.9 1 1 1 2 2 2 0 Nup133 N terminal like DivIC PF04977.10 KFX95632.1 - 0.18 11.3 0.2 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Na_Ca_ex PF01699.19 KFX95633.1 - 1.5e-48 163.9 34.0 1e-25 89.9 8.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TFIIE_beta PF02186.10 KFX95634.1 - 1.3e-05 25.0 0.1 8.7e-05 22.4 0.1 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain LZ_Tnp_IS66 PF13007.2 KFX95634.1 - 1.6 9.4 9.5 8.4 7.1 1.2 2.6 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF3275 PF11679.3 KFX95634.1 - 2.3 7.7 4.8 4.5 6.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Ribosomal_60s PF00428.14 KFX95634.1 - 10 6.6 7.9 15 6.0 2.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.7 KFX95635.1 - 7.6e-29 100.1 20.9 7.6e-29 100.1 14.5 17.4 5 3 9 15 15 15 5 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KFX95635.1 - 0.0034 17.1 14.1 0.0034 17.1 9.8 22.8 13 6 9 23 23 23 3 TATA element modulatory factor 1 DNA binding Hexapep PF00132.19 KFX95636.1 - 2.4e-11 42.5 8.4 1e-07 31.0 0.3 4.1 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX95636.1 - 8.3e-05 22.0 12.6 0.49 9.9 3.1 4.0 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.12 KFX95637.1 - 2.5e-46 157.1 0.0 5.1e-46 156.1 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KFX95637.1 - 3.6e-18 64.4 0.9 3.6e-18 64.4 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KFX95637.1 - 9e-10 38.2 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Complex1_LYR_2 PF13233.1 KFX95638.1 - 4.1e-22 78.6 0.5 5.5e-22 78.2 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX95638.1 - 0.15 11.8 2.8 0.21 11.4 0.5 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX95638.1 - 0.92 9.7 5.5 0.74 10.0 1.7 2.3 2 1 0 2 2 2 0 Complex1_LYR-like MMR_HSR1 PF01926.18 KFX95639.1 - 5.2e-20 71.5 0.0 8e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX95639.1 - 6.6e-06 25.6 0.0 8e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFX95639.1 - 0.00038 20.3 0.1 0.04 13.7 0.3 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KFX95639.1 - 0.0016 17.7 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX95639.1 - 0.0042 16.2 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KFX95639.1 - 0.0081 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AIG1 PF04548.11 KFX95639.1 - 0.093 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.8 KFX95639.1 - 0.098 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 KFX95639.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MOZ_SAS PF01853.13 KFX95643.1 - 1.7e-78 262.1 0.0 2.6e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KFX95643.1 - 0.00037 20.1 8.0 0.00037 20.1 5.5 1.9 2 0 0 2 2 2 1 PHD-finger zf-MIZ PF02891.15 KFX95643.1 - 0.031 13.8 1.1 0.068 12.6 0.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Pro_CA PF00484.14 KFX95645.1 - 1.6e-46 158.0 0.1 2e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.21 KFX95646.1 - 1.7e-21 75.5 0.7 3e-21 74.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.15 KFX95647.1 - 7.9e-19 67.8 0.0 1.5e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 KFX95647.1 - 0.0051 16.2 1.1 0.0051 16.2 0.8 4.1 5 0 0 5 5 5 1 RecR protein tRNA_Me_trans PF03054.11 KFX95647.1 - 0.0089 14.6 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase DUF2392 PF10288.4 KFX95647.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) zf-UBR PF02207.15 KFX95647.1 - 6.3 6.5 7.8 1.1 9.0 0.5 2.4 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) OCD_Mu_crystall PF02423.10 KFX95648.1 - 6.5e-11 41.5 0.6 1.3e-06 27.4 0.2 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Glyco_hydro_42M PF08532.5 KFX95648.1 - 0.037 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Aldo_ket_red PF00248.16 KFX95649.1 - 3e-65 219.8 0.0 5.1e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 KFX95649.1 - 9e-61 205.5 0.0 1.3e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX95649.1 - 2.6e-33 115.3 0.0 5.5e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX95649.1 - 6.6e-06 25.2 0.1 0.0046 15.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX95649.1 - 0.00013 20.9 0.0 0.097 11.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX95649.1 - 0.00016 21.6 0.0 0.00062 19.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX95649.1 - 0.0013 17.8 0.5 0.0045 16.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KFX95649.1 - 0.0074 15.2 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX95649.1 - 0.054 13.3 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX95649.1 - 0.1 11.0 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.13 KFX95650.1 - 0.00013 21.7 10.8 0.00013 21.7 7.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KFX95651.1 - 2.8e-22 78.6 0.3 4.1e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX95651.1 - 2e-14 54.5 0.0 3.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX95651.1 - 1.2e-10 41.1 0.0 3.6e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Herpes_UL21 PF03252.8 KFX95651.1 - 0.027 12.9 0.0 0.037 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 DAO PF01266.19 KFX95652.1 - 9.6e-18 64.1 0.1 1.5e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase PTR2 PF00854.16 KFX95653.1 - 3.5e-28 98.4 1.7 5.2e-25 88.0 1.2 2.4 1 1 0 1 1 1 1 POT family NLPC_P60 PF00877.14 KFX95654.1 - 7.5e-22 77.1 0.1 1.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.6 KFX95654.1 - 0.00061 19.9 0.8 0.0024 18.0 0.1 2.4 3 0 0 3 3 3 1 Bacterial SH3 domain DUF830 PF05708.7 KFX95654.1 - 0.02 14.8 0.0 0.89 9.5 0.0 2.5 3 0 0 3 3 3 0 Orthopoxvirus protein of unknown function (DUF830) Abhydrolase_6 PF12697.2 KFX95655.1 - 1.1e-24 87.6 0.0 2.3e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX95655.1 - 4.8e-22 78.6 0.0 9.9e-21 74.3 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX95655.1 - 2.2e-12 46.9 0.0 8.6e-12 45.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KFX95655.1 - 0.0046 16.8 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein Zn_clus PF00172.13 KFX95655.1 - 0.0046 16.8 2.6 0.0076 16.1 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_4 PF12146.3 KFX95655.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KFX95655.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase BTV_NS2 PF04514.7 KFX95655.1 - 0.2 10.4 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 OrfB_Zn_ribbon PF07282.6 KFX95657.1 - 4.8 6.9 7.4 3.3 7.4 0.9 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Alph_Pro_TM PF09608.5 KFX95658.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Fumble PF03630.9 KFX95659.1 - 6e-133 442.9 0.0 1.2e-131 438.6 0.0 2.1 1 1 0 1 1 1 1 Fumble RhaA PF06134.6 KFX95659.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) Ctr PF04145.10 KFX95669.1 - 3.6e-08 33.5 0.1 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Diphthamide_syn PF01866.12 KFX95671.1 - 1.3e-50 172.3 0.0 1.5e-50 172.2 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pox_Ag35 PF03286.9 KFX95672.1 - 0.14 11.6 0.1 0.36 10.3 0.0 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein DUF3779 PF12621.3 KFX95673.1 - 1.7e-15 56.6 0.0 1.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Phosphate metabolism protein FUSC PF04632.7 KFX95682.1 - 0.024 13.0 2.4 0.031 12.7 1.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DSPc PF00782.15 KFX95688.1 - 7.3e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX95688.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFX95688.1 - 0.0049 17.1 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family APH PF01636.18 KFX95689.1 - 2.3e-07 30.8 0.0 6e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX95689.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase BTB PF00651.26 KFX95690.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.11 KFX95691.1 - 1.2e-29 103.1 15.2 1.2e-29 103.1 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95691.1 - 7.2e-08 31.4 9.9 7.2e-08 31.4 6.9 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX95691.1 - 7.1e-05 21.3 2.8 7.1e-05 21.3 1.9 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein DUF791 PF05631.9 KFX95691.1 - 0.00015 20.5 0.4 0.00029 19.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Actin PF00022.14 KFX95701.1 - 9.9e-38 129.5 0.0 1.2e-34 119.3 0.0 2.2 2 1 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 KFX95702.1 - 1.3e-28 98.6 5.0 1.4e-28 98.5 3.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KFX95702.1 - 0.0086 16.0 0.3 0.0098 15.8 0.2 1.1 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 KFX95702.1 - 0.029 14.0 3.2 0.036 13.7 2.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 YL1_C PF08265.6 KFX95703.1 - 1.5e-15 56.3 0.1 2.3e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 KFX95704.1 - 1.7e-17 63.6 13.8 2e-17 63.3 9.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3185 PF11381.3 KFX95704.1 - 7.7 6.3 10.2 13 5.5 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF3487 PF11990.3 KFX95704.1 - 8.3 5.8 9.6 0.3 10.4 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) Pyridoxal_deC PF00282.14 KFX95705.1 - 1.1e-120 402.5 0.0 1.3e-120 402.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF427 PF04248.7 KFX95706.1 - 3.8e-31 106.6 1.5 4.2e-31 106.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Zn_clus PF00172.13 KFX95707.1 - 5.1e-09 35.8 7.3 5.1e-09 35.8 5.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX95707.1 - 1.3e-05 24.2 0.0 2.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_CA PF00484.14 KFX95708.1 - 1.3e-31 109.6 0.1 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AhpC-TSA PF00578.16 KFX95713.1 - 3.9e-29 100.8 0.0 8.1e-29 99.8 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KFX95713.1 - 7.5e-20 70.9 0.0 1.9e-18 66.3 0.0 2.1 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KFX95713.1 - 0.0037 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 KFX95713.1 - 0.0056 16.1 0.0 0.0074 15.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Acetyltransf_3 PF13302.1 KFX95714.1 - 2.4e-19 69.8 0.0 3.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX95714.1 - 5.3e-06 26.3 0.0 8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FAT PF02259.18 KFX95715.1 - 7.2e-76 255.4 5.7 1.8e-75 254.1 4.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KFX95715.1 - 1.8e-27 96.3 0.2 7.2e-27 94.3 0.1 2.2 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFX95715.1 - 6.8e-08 31.8 0.2 1.8e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 FATC domain Menin PF05053.8 KFX95715.1 - 1.1 7.3 4.6 2.2 6.3 3.2 1.4 1 0 0 1 1 1 0 Menin DUF1962 PF09227.5 KFX95715.1 - 3.1 7.9 0.2 7.3 6.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) Fungal_trans PF04082.13 KFX95716.1 - 4.9e-29 100.9 0.0 2e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.1 KFX95716.1 - 7.5e-09 36.0 0.0 2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KFX95716.1 - 1.3e-06 28.2 13.6 2.2e-06 27.4 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_4 PF13661.1 KFX95716.1 - 9.7e-06 25.1 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Gal4_dimer PF03902.8 KFX95716.1 - 0.17 11.8 0.1 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain Metallophos PF00149.23 KFX95717.1 - 1.5e-16 60.3 0.9 2.5e-16 59.6 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX95717.1 - 0.00038 20.3 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PCMT PF01135.14 KFX95718.1 - 4.8e-48 163.4 0.0 4.8e-47 160.1 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 KFX95718.1 - 6.4e-22 77.9 0.0 2.2e-21 76.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Methyltransf_31 PF13847.1 KFX95718.1 - 8.1e-08 31.9 0.0 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.12 KFX95718.1 - 2.6e-07 29.9 0.0 1.3e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Methyltransf_18 PF12847.2 KFX95718.1 - 3.4e-07 30.8 0.0 7.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX95718.1 - 3.3e-05 23.8 0.0 7.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFX95718.1 - 0.00016 21.4 0.0 0.00059 19.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX95718.1 - 0.0022 17.7 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFX95718.1 - 0.0041 16.1 0.0 0.0089 15.0 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 KFX95718.1 - 0.0067 15.4 0.0 0.034 13.1 0.0 2.1 3 0 0 3 3 3 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 KFX95718.1 - 0.008 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFX95718.1 - 0.06 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFX95718.1 - 0.12 12.8 0.1 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KFX95719.1 - 7.3e-36 123.5 34.0 1.4e-34 119.3 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KFX95720.1 - 2.1e-48 164.8 16.0 2.1e-48 164.8 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95720.1 - 1.6e-11 43.4 7.3 1.6e-11 43.4 5.1 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KFX95720.1 - 2.9e-06 25.7 2.2 6.8e-06 24.4 1.5 1.6 1 0 0 1 1 1 1 Transmembrane secretion effector DUF791 PF05631.9 KFX95720.1 - 0.00049 18.9 3.3 0.0024 16.6 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KFX95720.1 - 0.085 12.6 10.9 0.16 11.8 0.1 3.3 3 1 1 4 4 4 0 MFS_1 like family ATG22 PF11700.3 KFX95720.1 - 0.25 9.7 0.0 0.25 9.7 0.0 3.5 3 1 1 4 4 4 0 Vacuole effluxer Atg22 like Isochorismatase PF00857.15 KFX95721.1 - 1.4e-32 112.9 0.0 1.6e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.13 KFX95722.1 - 8.1e-11 41.2 0.8 8.1e-11 41.2 0.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain WD40 PF00400.27 KFX95727.1 - 3.8e-12 45.5 3.9 0.00091 19.0 0.6 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat STT3 PF02516.9 KFX95728.1 - 3.3e-133 445.1 39.9 2.6e-128 429.0 26.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.7 KFX95728.1 - 2.9e-19 68.7 0.7 7.2e-19 67.5 0.1 2.0 2 0 0 2 2 2 1 ATP synthase E chain Chromo PF00385.19 KFX95729.1 - 0.0027 17.3 1.6 0.0067 16.0 1.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Proteasom_PSMB PF10508.4 KFX95729.1 - 0.041 12.1 0.1 5 5.2 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF3347 PF11827.3 KFX95730.1 - 0.061 13.3 0.1 0.074 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) YukC PF10140.4 KFX95730.1 - 0.063 11.8 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC SET PF00856.23 KFX95731.1 - 2.5e-08 34.3 0.2 6e-07 29.9 0.1 2.3 1 1 0 1 1 1 1 SET domain SPT2 PF08243.6 KFX95732.1 - 7.7e-08 32.6 10.9 2.4e-07 31.0 7.6 1.9 1 0 0 1 1 1 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 KFX95733.1 - 3.4e-27 94.6 10.1 3.9e-27 94.4 7.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 KFX95733.1 - 0.059 11.5 0.9 0.06 11.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S19 PF00203.16 KFX95734.1 - 1.7e-33 114.0 0.4 2.5e-33 113.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 KFX95734.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Prp19_bind PF06991.6 KFX95757.1 - 6.4e-47 160.1 34.7 6.4e-47 160.1 24.1 2.0 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain DUF3129 PF11327.3 KFX95768.1 - 8.8e-19 68.0 0.4 9.9e-19 67.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) AMP-binding PF00501.23 KFX95769.1 - 2.9e-90 302.6 0.0 3.5e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX95769.1 - 5.5e-09 36.8 0.0 1.5e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_3 PF13738.1 KFX95770.1 - 2.4e-16 60.4 0.0 8.7e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX95770.1 - 5.8e-14 51.7 0.0 9.8e-10 37.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFX95770.1 - 7.6e-10 37.6 0.0 3.8e-09 35.3 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like SnoaL_2 PF12680.2 KFX95770.1 - 0.00014 22.1 0.1 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_4 PF13577.1 KFX95770.1 - 0.00044 20.1 0.7 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain Pyr_redox_2 PF07992.9 KFX95770.1 - 0.00054 19.8 0.2 0.025 14.4 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX95770.1 - 0.00058 20.2 0.1 0.0061 16.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX95770.1 - 0.00094 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF4440 PF14534.1 KFX95770.1 - 0.01 16.0 0.1 0.036 14.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 KFX95770.1 - 0.015 15.3 0.1 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Thi4 PF01946.12 KFX95770.1 - 0.041 12.9 0.1 7.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.11 KFX95771.1 - 4e-31 108.0 37.4 4e-31 108.0 25.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFX95771.1 - 0.0013 18.2 4.2 0.0029 17.1 2.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 LRR_6 PF13516.1 KFX95772.1 - 0.0035 17.2 10.8 20 5.6 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 KFX95772.1 - 0.011 15.3 7.5 1 9.0 0.1 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX95772.1 - 0.27 11.4 7.6 64 4.1 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat tRNA-synt_1 PF00133.17 KFX95776.1 - 2.8e-162 540.8 0.0 5.1e-162 539.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Kinesin PF00225.18 KFX95776.1 - 2.9e-107 358.2 0.2 2.9e-107 358.2 0.2 1.8 2 0 0 2 2 2 1 Kinesin motor domain tRNA-synt_1g PF09334.6 KFX95776.1 - 6.1e-20 71.2 3.9 2.7e-09 36.1 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFX95776.1 - 5e-17 62.0 0.0 1.6e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Microtub_bind PF13931.1 KFX95776.1 - 2.3e-10 40.8 3.8 2.3e-10 40.8 2.6 4.4 3 1 0 4 4 4 1 Kinesin-associated microtubule-binding Fungal_trans_2 PF11951.3 KFX95776.1 - 0.00066 18.3 0.1 0.00066 18.3 0.1 3.6 4 0 0 4 4 4 2 Fungal specific transcription factor domain zf-FPG_IleRS PF06827.9 KFX95776.1 - 0.017 14.7 0.2 0.044 13.4 0.1 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS SMK-1 PF04802.10 KFX95786.1 - 1.6e-73 246.3 0.2 3.6e-73 245.2 0.2 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ank_2 PF12796.2 KFX95786.1 - 5.3e-60 199.7 0.0 1.2e-12 47.9 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95786.1 - 1.2e-48 160.5 0.0 2e-05 24.1 0.0 11.6 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KFX95786.1 - 4.4e-47 157.6 0.0 2.8e-10 40.4 0.0 7.1 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX95786.1 - 1.4e-42 142.6 0.8 1.3e-06 28.4 0.0 8.8 2 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95786.1 - 2.7e-37 123.0 0.0 0.004 17.2 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat AAA_22 PF13401.1 KFX95786.1 - 1.7e-05 24.9 0.0 5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFX95786.1 - 0.00045 19.9 0.4 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF605 PF04652.11 KFX95787.1 - 0.99 8.7 15.4 1.3 8.3 10.7 1.2 1 0 0 1 1 1 0 Vta1 like MOR2-PAG1_N PF14222.1 KFX95790.1 - 9.9e-218 724.2 0.0 2.2e-217 723.1 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KFX95790.1 - 1.1e-90 303.9 0.1 3.1e-90 302.4 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KFX95790.1 - 3.3e-33 114.4 7.1 7.4e-12 43.7 0.0 3.9 3 1 1 4 4 4 3 Cell morphogenesis central region HEAT_2 PF13646.1 KFX95790.1 - 0.0028 17.9 1.8 0.29 11.4 0.0 5.2 7 0 0 7 7 7 1 HEAT repeats HEAT PF02985.17 KFX95790.1 - 0.0057 16.6 0.5 3.3 8.0 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat AMMECR1 PF01871.12 KFX95792.1 - 6.6e-45 152.2 0.0 1e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Esterase_phd PF10503.4 KFX95792.1 - 1.9e-06 27.2 0.0 0.00034 19.9 0.0 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.15 KFX95792.1 - 7.6e-05 22.2 0.1 0.00027 20.4 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.2 KFX95792.1 - 0.00012 21.8 0.0 0.00051 19.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX95792.1 - 0.0011 18.1 0.2 0.019 14.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 KFX95792.1 - 0.23 9.8 0.0 2.8 6.3 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) 4HBT_3 PF13622.1 KFX95793.1 - 6.2e-30 104.7 0.5 7.9e-30 104.4 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Metallophos PF00149.23 KFX95794.1 - 3.8e-43 147.2 2.0 4.9e-43 146.8 0.9 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase OmpH PF03938.9 KFX95794.1 - 0.71 9.7 18.4 0.28 11.1 5.7 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AUX_IAA PF02309.11 KFX95794.1 - 5.8 6.5 8.6 13 5.4 5.9 1.5 1 0 0 1 1 1 0 AUX/IAA family Vps51 PF08700.6 KFX95795.1 - 7.2e-16 57.8 2.9 7.2e-16 57.8 2.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KFX95795.1 - 0.0085 15.9 3.8 0.0087 15.9 0.1 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2383 PF09537.5 KFX95795.1 - 0.35 11.1 4.5 6.6 7.0 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Sec5 PF15469.1 KFX95795.1 - 0.49 10.0 7.7 1.9 8.2 0.3 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 DUF2443 PF10398.4 KFX95795.1 - 0.52 10.1 4.6 2 8.2 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) IncA PF04156.9 KFX95795.1 - 3.1 7.3 8.8 0.1 12.1 0.2 2.5 2 1 0 2 2 2 0 IncA protein MAS20 PF02064.10 KFX95796.1 - 3.4e-21 75.3 0.6 2.5e-20 72.6 0.4 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor DUF533 PF04391.7 KFX95796.1 - 0.017 14.5 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF1079 PF06435.6 KFX95796.1 - 0.034 14.0 0.2 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) AAA_32 PF13654.1 KFX95796.1 - 0.26 9.8 3.1 0.34 9.5 2.2 1.1 1 0 0 1 1 1 0 AAA domain DHC_N1 PF08385.7 KFX95797.1 - 2.5e-188 627.1 6.8 2.5e-188 627.1 4.7 5.1 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KFX95797.1 - 2.9e-126 421.2 5.5 2.9e-126 421.2 3.8 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KFX95797.1 - 1.5e-101 340.5 0.0 5.5e-101 338.7 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KFX95797.1 - 1e-78 264.0 0.0 3.3e-78 262.4 0.0 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KFX95797.1 - 4.2e-43 146.8 0.2 3.5e-42 143.8 0.1 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KFX95797.1 - 6.8e-43 146.5 0.3 2.5e-41 141.4 0.2 2.8 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KFX95797.1 - 5.6e-37 127.2 6.4 2e-36 125.4 4.5 2.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KFX95797.1 - 2.3e-32 111.5 0.9 1.4e-11 44.2 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KFX95797.1 - 1.1e-20 73.8 0.0 6.5e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KFX95797.1 - 9.9e-16 58.0 0.0 0.0097 16.0 0.0 6.1 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 KFX95797.1 - 4.9e-14 52.6 0.0 0.0037 17.4 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFX95797.1 - 4.1e-10 39.7 2.8 0.14 12.0 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 KFX95797.1 - 4.2e-10 40.4 2.4 0.03 15.1 0.0 6.6 6 0 0 6 6 5 2 AAA domain T2SE PF00437.15 KFX95797.1 - 8.8e-09 34.6 0.0 0.044 12.6 0.0 3.9 4 0 0 4 4 4 3 Type II/IV secretion system protein AAA_18 PF13238.1 KFX95797.1 - 1.1e-08 35.4 1.5 0.015 15.6 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.1 KFX95797.1 - 1e-06 28.4 0.4 0.89 9.3 0.0 5.0 5 0 0 5 5 4 1 Part of AAA domain AAA_16 PF13191.1 KFX95797.1 - 4.1e-06 26.9 17.2 0.19 11.7 0.1 8.6 9 1 1 10 10 10 2 AAA ATPase domain Mg_chelatase PF01078.16 KFX95797.1 - 9.2e-06 24.9 0.8 0.5 9.4 0.0 4.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KFX95797.1 - 3.5e-05 23.2 0.1 2 7.9 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KFX95797.1 - 0.0003 19.9 0.0 0.95 8.5 0.0 3.7 3 0 0 3 3 3 2 Zeta toxin FtsK_SpoIIIE PF01580.13 KFX95797.1 - 0.00035 20.1 0.0 5.9 6.3 0.0 4.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KFX95797.1 - 0.0011 19.2 4.9 3.6 7.8 0.0 5.1 4 0 0 4 4 3 2 ABC transporter RNA_helicase PF00910.17 KFX95797.1 - 0.0074 16.4 0.1 44 4.3 0.0 4.8 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 KFX95797.1 - 0.017 14.8 0.6 11 5.6 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFX95797.1 - 0.017 14.5 0.7 7 6.1 0.1 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KFX95797.1 - 0.019 14.3 2.7 0.4 10.0 0.0 3.9 5 0 0 5 5 5 0 AAA domain Fungal_trans PF04082.13 KFX95800.1 - 3.9e-27 94.7 4.0 3.9e-27 94.7 2.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95800.1 - 6.7e-10 38.7 9.2 1.3e-09 37.7 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 KFX95801.1 - 1.8e-18 67.0 0.0 2.3e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 KFX95802.1 - 5.7e-75 252.6 23.5 5.7e-75 252.6 16.3 2.5 2 0 0 2 2 1 1 Sugar (and other) transporter DUF2422 PF10337.4 KFX95802.1 - 3.5e-57 194.2 7.7 5.1e-56 190.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) NmrA PF05368.8 KFX95802.1 - 2.1e-29 102.4 0.0 1e-28 100.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family MFS_1 PF07690.11 KFX95802.1 - 4.2e-11 42.1 46.1 1.1e-10 40.7 12.4 4.5 2 2 1 3 3 2 2 Major Facilitator Superfamily NAD_binding_10 PF13460.1 KFX95802.1 - 1.6e-10 41.2 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding FUSC_2 PF13515.1 KFX95802.1 - 8.9e-10 38.5 22.0 8.9e-10 38.5 15.3 5.0 4 1 0 4 4 4 1 Fusaric acid resistance protein-like KR PF08659.5 KFX95802.1 - 0.00099 18.8 0.3 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 KFX95802.1 - 0.0058 15.3 0.0 0.0099 14.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX95802.1 - 0.0097 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DUF2421 PF10334.4 KFX95802.1 - 0.019 14.5 0.0 2.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2421) Epimerase PF01370.16 KFX95802.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF605 PF04652.11 KFX95802.1 - 1.4 8.2 5.5 2.7 7.2 3.8 1.4 1 0 0 1 1 1 0 Vta1 like TraK PF06586.6 KFX95803.1 - 0.031 13.4 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 TraK protein Ndc1_Nup PF09531.5 KFX95805.1 - 3.8 5.8 5.6 4.5 5.5 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glu-tRNAGln PF02686.10 KFX95835.1 - 1e-06 28.4 0.7 6e-06 25.9 0.5 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF4226 PF10774.4 KFX95835.1 - 0.056 13.4 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) SNAP PF14938.1 KFX95836.1 - 2.4e-112 374.7 13.4 2.7e-112 374.5 9.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFX95836.1 - 3.7e-09 36.3 10.0 0.00013 21.8 2.8 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX95836.1 - 2.8e-06 26.6 6.8 0.025 14.3 0.3 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX95836.1 - 1.2e-05 24.8 11.6 0.028 14.0 0.3 3.4 1 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFX95836.1 - 0.0028 17.1 8.1 2.7 7.7 0.0 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX95836.1 - 0.0039 16.8 9.1 0.1 12.4 0.4 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX95836.1 - 0.0044 16.8 9.5 2.3 8.3 0.1 5.4 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX95836.1 - 0.0062 17.1 9.6 0.88 10.3 0.3 3.9 1 1 3 4 4 4 2 Tetratricopeptide repeat DUF2521 PF10730.4 KFX95836.1 - 0.034 13.9 1.5 0.075 12.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2521) TPR_6 PF13174.1 KFX95836.1 - 0.18 12.3 12.6 8.9 7.0 0.1 5.5 3 1 2 6 6 6 0 Tetratricopeptide repeat DUF4375 PF14300.1 KFX95836.1 - 0.26 11.2 4.1 3.6 7.6 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4375) DUF2225 PF09986.4 KFX95836.1 - 1.7 8.0 5.6 5.3 6.4 3.7 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) BING4CT PF08149.6 KFX95837.1 - 7e-40 134.4 0.0 9.2e-37 124.4 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 KFX95837.1 - 6.2e-08 32.2 0.0 5.4e-05 22.9 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KFX95837.1 - 0.042 12.6 0.0 0.11 11.3 0.0 1.6 1 1 0 1 1 1 0 Coatomer WD associated region DUF663 PF04950.7 KFX95838.1 - 9e-104 346.5 0.0 1.3e-103 346.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFX95838.1 - 5.6e-19 67.4 0.0 1.4e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain FA_desaturase PF00487.19 KFX95839.1 - 2.1e-31 109.2 11.5 3.2e-31 108.7 8.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KFX95839.1 - 2.9e-19 67.9 0.5 5.4e-19 67.1 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 KFX95840.1 - 5e-25 87.2 0.2 8.7e-25 86.4 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 KFX95840.1 - 0.046 13.1 0.5 0.17 11.2 0.1 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) CRISPR_Cse2 PF09485.5 KFX95840.1 - 0.23 11.5 1.2 0.52 10.3 0.4 1.8 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) UBX PF00789.15 KFX95841.1 - 2.6e-05 24.1 0.0 7.4e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 KFX95841.1 - 0.0039 16.9 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 KFX95841.1 - 0.016 15.2 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFX95841.1 - 0.059 13.7 0.3 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type UBA_2 PF08587.6 KFX95841.1 - 0.066 13.4 0.5 0.58 10.3 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) zf-C2H2_jaz PF12171.3 KFX95841.1 - 0.15 12.2 0.3 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 KFX95841.1 - 0.3 11.0 7.5 0.31 11.0 4.2 1.8 1 1 0 1 1 1 0 CpXC protein APG6 PF04111.7 KFX95841.1 - 0.84 8.6 20.0 1.7 7.6 13.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA PF00004.24 KFX95847.1 - 4.5e-39 133.6 0.0 1.4e-38 132.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KFX95847.1 - 6e-06 26.6 0.4 0.22 11.8 0.0 3.9 4 0 0 4 4 4 2 ABC transporter RuvB_N PF05496.7 KFX95847.1 - 1.6e-05 24.0 0.2 0.00016 20.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFX95847.1 - 3.7e-05 23.8 0.3 0.001 19.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KFX95847.1 - 4.3e-05 22.4 0.1 0.00031 19.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 KFX95847.1 - 0.00018 22.3 0.1 0.00083 20.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFX95847.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFX95847.1 - 0.00031 20.4 0.0 0.00097 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX95847.1 - 0.00036 20.5 0.2 0.0094 15.9 0.0 3.1 1 1 2 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KFX95847.1 - 0.00043 20.1 0.0 0.0017 18.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX95847.1 - 0.00044 20.5 0.1 0.003 17.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KFX95847.1 - 0.00069 19.0 0.1 0.0042 16.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KFX95847.1 - 0.0009 19.1 0.0 0.0074 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KFX95847.1 - 0.00097 19.0 0.0 0.0036 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFX95847.1 - 0.0019 17.3 0.0 0.0046 16.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFX95847.1 - 0.0031 17.6 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 KFX95847.1 - 0.0033 17.0 0.1 0.01 15.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFX95847.1 - 0.0066 16.0 0.1 0.95 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX95847.1 - 0.0077 15.9 0.1 0.036 13.8 0.1 2.2 1 0 0 1 1 1 1 Part of AAA domain Parvo_NS1 PF01057.12 KFX95847.1 - 0.0099 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 KFX95847.1 - 0.011 15.1 0.2 0.044 13.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KFX95847.1 - 0.012 15.3 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 KFX95847.1 - 0.015 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 KFX95847.1 - 0.018 14.4 0.2 7.2 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 KFX95847.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF4050 PF13259.1 KFX95848.1 - 4.9e-29 100.7 0.0 1.2e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF2514 PF10721.4 KFX95849.1 - 0.0019 17.8 4.1 0.0024 17.5 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Mnd1 PF03962.10 KFX95849.1 - 0.014 15.0 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Mnd1 family Ubiq-Cytc-red_N PF09165.5 KFX95849.1 - 0.11 12.7 1.1 2.7 8.3 0.0 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Mus7 PF09462.5 KFX95853.1 - 6.9e-57 193.6 0.0 9.8e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Cys_Met_Meta_PP PF01053.15 KFX95854.1 - 1.4e-57 194.8 0.0 2.8e-57 193.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFX95854.1 - 0.00015 20.8 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFX95854.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FMN_bind_2 PF04299.7 KFX95855.1 - 1e-55 187.8 0.0 1.3e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.3 KFX95856.1 - 5.6e-47 160.1 8.0 6.7e-47 159.8 5.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.23 KFX95865.1 - 5.8e-12 45.4 0.0 1.2e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Acylphosphatase PF00708.13 KFX95867.1 - 9.9e-22 76.8 0.8 1.1e-21 76.7 0.5 1.0 1 0 0 1 1 1 1 Acylphosphatase Ank_2 PF12796.2 KFX95868.1 - 6.7e-29 100.0 0.1 2.2e-16 59.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95868.1 - 1e-24 85.0 0.1 5.2e-06 26.0 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KFX95868.1 - 8.2e-22 77.1 0.3 8.7e-07 29.3 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX95868.1 - 2.5e-17 62.5 0.8 8.7e-08 32.1 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95868.1 - 1.1e-15 56.1 0.0 0.0061 16.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat DUF2232 PF09991.4 KFX95868.1 - 0.038 13.0 0.2 0.056 12.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FliD_N PF02465.13 KFX95868.1 - 0.84 10.0 4.4 1.4 9.3 0.3 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Glyco_hydro_12 PF01670.11 KFX95869.1 - 1.5e-37 128.8 1.4 1.5e-37 128.8 1.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 KFX95869.1 - 0.82 9.8 4.9 0.51 10.5 1.1 2.3 1 1 0 2 2 2 0 Phage holin FAA_hydrolase PF01557.13 KFX95870.1 - 1.5e-52 178.2 0.0 1.7e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hep_59 PF07052.6 KFX95883.1 - 8.1e-10 39.0 0.1 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Pkinase PF00069.20 KFX95892.1 - 1.2e-61 208.2 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95892.1 - 3e-30 105.1 0.0 3.8e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX95892.1 - 1.9e-05 23.8 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX95892.1 - 0.003 17.3 0.0 0.0072 16.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX95892.1 - 0.036 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFX95892.1 - 0.096 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_S8 PF00082.17 KFX95894.1 - 2.8e-53 180.8 9.6 3.2e-53 180.7 5.9 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFX95894.1 - 1.2e-19 70.6 0.2 1.2e-19 70.6 0.1 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 Beach PF02138.13 KFX95895.1 - 2.9e-107 358.1 0.1 7.4e-107 356.7 0.1 1.7 1 0 0 1 1 1 1 Beige/BEACH domain HLH PF00010.21 KFX95895.1 - 7e-16 57.6 0.1 3.2e-15 55.5 0.1 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PH_BEACH PF14844.1 KFX95895.1 - 4.3e-10 39.3 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KFX95895.1 - 5.6e-10 39.6 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KFX95895.1 - 4.9e-08 32.5 0.6 0.0002 21.0 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat FAD_binding_3 PF01494.14 KFX95896.1 - 2.1e-18 66.5 0.0 7e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFX95896.1 - 3.9e-08 32.8 0.0 0.0001 21.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFX95896.1 - 0.011 14.7 0.1 0.034 13.0 0.0 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX95896.1 - 0.031 14.3 0.1 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX95896.1 - 0.11 11.4 0.5 7.5 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX95896.1 - 0.34 11.3 3.0 11 6.5 0.1 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.8 KFX95898.1 - 1.1e-43 149.4 0.4 1.5e-43 148.8 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein TctB PF07331.6 KFX95898.1 - 1 9.0 10.1 0.083 12.5 0.7 2.6 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family MatE PF01554.13 KFX95898.1 - 9.1 5.8 12.8 0.14 11.7 2.5 2.6 3 1 0 3 3 3 0 MatE PhyH PF05721.8 KFX95899.1 - 6.8e-05 22.9 0.1 0.00018 21.6 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 KFX95900.1 - 3.2e-38 131.3 26.9 3.2e-38 131.3 18.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KFX95900.1 - 0.11 10.5 4.7 0.63 8.0 0.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF914 PF06027.7 KFX95901.1 - 9.1e-107 356.7 21.5 1.1e-106 356.4 14.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFX95901.1 - 0.00025 21.0 12.3 0.00025 21.0 8.5 2.4 2 1 0 2 2 2 1 EamA-like transporter family Tim17 PF02466.14 KFX95901.1 - 0.038 14.0 0.4 0.091 12.8 0.2 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family TPT PF03151.11 KFX95901.1 - 9.8 5.8 28.1 1.1 8.9 5.7 3.2 2 1 1 3 3 3 0 Triose-phosphate Transporter family Methyltransf_23 PF13489.1 KFX95903.1 - 7e-12 45.3 0.1 1.3e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX95903.1 - 1.3e-08 35.3 0.0 1.8e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX95903.1 - 3.5e-05 24.1 0.0 7.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX95903.1 - 3.8e-05 23.3 0.0 0.0004 19.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX95903.1 - 5.8e-05 23.5 0.0 0.00056 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX95903.1 - 0.00052 20.3 0.0 0.0027 18.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX95903.1 - 0.0022 17.0 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 KFX95903.1 - 0.038 13.1 0.1 0.082 12.0 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 KFX95903.1 - 0.047 13.7 0.0 0.16 12.0 0.0 1.9 2 1 0 2 2 1 0 Methyltransferase domain CheR PF01739.13 KFX95903.1 - 0.049 12.9 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.7 KFX95903.1 - 0.069 12.4 0.3 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.9 KFX95903.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HD PF01966.17 KFX95904.1 - 2.6e-08 33.8 0.3 3.3e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 HD domain Pkinase PF00069.20 KFX95906.1 - 2.9e-07 29.9 0.0 4.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX95906.1 - 0.00023 20.9 0.2 0.00035 20.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFX95906.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.22 KFX95915.1 - 2e-66 219.7 6.7 5.2e-23 80.5 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFX95915.1 - 2.8e-22 78.6 2.0 2.4e-10 40.4 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFX95915.1 - 9e-20 68.4 7.5 3.5e-06 25.9 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFX95915.1 - 2.9e-18 64.0 7.1 0.00019 21.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KFX95915.1 - 1.5e-15 56.5 4.5 1.9e-07 30.5 0.0 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFX95915.1 - 4.8e-14 50.9 9.0 5.8e-06 25.4 0.1 3.6 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.4 KFX95915.1 - 7.2e-06 25.9 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFX95915.1 - 0.014 15.3 0.4 2.2 8.2 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain Cyclin_N PF00134.18 KFX95916.1 - 6.3e-11 41.9 0.1 1.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA_assoc_C PF09821.4 KFX95916.1 - 0.094 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 C-terminal AAA-associated domain WD40 PF00400.27 KFX95919.1 - 9.9e-05 22.0 0.1 0.0012 18.6 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Cupin_8 PF13621.1 KFX95920.1 - 1.5e-35 122.9 0.0 2.8e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KFX95920.1 - 5.2e-24 84.8 0.0 7.7e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KFX95920.1 - 1.6e-15 56.5 15.3 9.7e-07 28.4 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KFX95920.1 - 6.1e-09 35.8 1.7 0.0037 17.3 0.0 4.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFX95920.1 - 1e-06 28.5 0.0 0.00062 19.6 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Cupin_4 PF08007.7 KFX95920.1 - 2.2e-05 23.8 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_6 PF13964.1 KFX95920.1 - 3.9e-05 23.6 7.2 0.0082 16.2 0.0 3.8 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 KFX95920.1 - 0.00097 18.6 1.3 0.78 9.3 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 KFX95920.1 - 0.022 14.5 6.8 0.069 12.9 0.2 3.8 4 0 0 4 4 4 0 Kelch motif PX PF00787.19 KFX95931.1 - 1.2e-13 50.8 0.0 1.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 PX domain GST_C PF00043.20 KFX95933.1 - 1.1e-08 34.9 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX95933.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX95933.1 - 0.00013 22.3 0.0 0.00016 22.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BP28CT PF08146.7 KFX95934.1 - 2.2e-36 124.9 0.2 2.2e-36 124.9 0.2 3.3 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KFX95934.1 - 2.3e-27 95.3 7.3 2.4e-26 92.0 0.0 4.9 3 1 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 EF-hand_4 PF12763.2 KFX95934.1 - 0.013 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HEAT PF02985.17 KFX95934.1 - 0.021 14.8 13.2 0.28 11.3 0.1 6.4 7 0 0 7 7 7 0 HEAT repeat HEAT_2 PF13646.1 KFX95934.1 - 0.24 11.7 24.9 0.61 10.3 0.1 7.3 7 1 0 7 7 7 0 HEAT repeats Flagellar_rod PF05149.7 KFX95935.1 - 0.086 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein Zip PF02535.17 KFX95941.1 - 7.3e-54 182.9 12.4 2.6e-53 181.0 8.6 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter YniB PF14002.1 KFX95941.1 - 0.066 12.6 0.1 0.066 12.6 0.1 1.7 2 0 0 2 2 2 0 YniB-like protein Pkinase PF00069.20 KFX95942.1 - 4.7e-47 160.3 0.0 6.8e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95942.1 - 6.4e-31 107.3 0.0 8.5e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX95942.1 - 0.0005 19.1 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFX95942.1 - 0.0049 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peroxidase_2 PF01328.12 KFX95943.1 - 4.5e-40 137.2 0.1 5.6e-40 136.9 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Zn_clus PF00172.13 KFX95944.1 - 2.3e-09 36.9 10.1 4e-09 36.2 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX95944.1 - 1e-06 27.6 0.1 1.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Endonuclease_NS PF01223.18 KFX95944.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.5 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease Glyco_hydro_28 PF00295.12 KFX95946.1 - 3.3e-34 118.3 9.6 4.8e-34 117.7 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 COesterase PF00135.23 KFX95947.1 - 3.2e-90 303.3 0.0 4.2e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX95947.1 - 1.2e-07 31.5 0.0 4.4e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX95947.1 - 0.022 14.0 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sulfakinin PF08257.6 KFX95947.1 - 0.16 11.8 0.9 0.51 10.3 0.6 1.9 1 0 0 1 1 1 0 Sulfakinin family FAD_binding_4 PF01565.18 KFX95948.1 - 4.8e-21 74.6 2.7 1.5e-20 73.1 1.9 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX95948.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.19 KFX95950.1 - 2.7e-76 256.9 23.0 3.1e-76 256.7 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95950.1 - 1.8e-37 128.8 51.2 7.4e-31 107.1 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX95950.1 - 0.00011 20.7 26.9 0.0022 16.4 7.1 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX95950.1 - 0.00096 17.4 0.6 0.002 16.3 0.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2463 PF09591.5 KFX95950.1 - 0.01 15.4 0.7 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Glyco_hydro_88 PF07470.8 KFX95951.1 - 1.3e-10 40.8 0.2 4.6e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.4 KFX95952.1 - 1.5e-127 425.1 0.1 1.9e-127 424.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.13 KFX95953.1 - 2.2e-17 62.7 0.1 7e-17 61.1 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95953.1 - 1.8e-06 27.7 10.9 2.9e-06 27.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1749 PF08538.5 KFX95955.1 - 9.8e-98 326.7 0.0 1.1e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KFX95955.1 - 1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95955.1 - 1.5e-06 27.9 0.0 2.8e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFX95955.1 - 0.00057 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 KFX95955.1 - 0.0083 15.7 0.3 0.051 13.1 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KFX95955.1 - 0.047 13.1 0.0 0.59 9.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) AMP-binding PF00501.23 KFX95956.1 - 1.3e-81 274.1 0.0 2e-76 257.0 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFX95956.1 - 2.4e-66 223.6 0.0 3.4e-38 131.1 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFX95956.1 - 4e-23 81.4 0.0 1.6e-11 44.3 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX95956.1 - 1.4e-06 29.1 0.0 0.092 13.7 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KFX95956.1 - 0.057 11.9 0.3 1.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Alcohol acetyltransferase MFS_1 PF07690.11 KFX95957.1 - 2.3e-23 82.4 56.1 2.2e-15 56.2 22.4 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX95957.1 - 7.6e-09 34.3 29.4 1e-08 33.9 19.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ECH PF00378.15 KFX95958.1 - 8.7e-49 165.8 0.0 1.1e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acetyltransf_8 PF13523.1 KFX95959.1 - 1.8e-35 122.0 0.1 2.7e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 KFX95960.1 - 1.2e-75 254.5 28.1 2.2e-42 145.3 4.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX95960.1 - 2.6e-62 209.1 0.0 5e-31 107.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX95960.1 - 1.9e-14 53.4 3.2 0.00066 18.9 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX95960.1 - 7.2e-10 39.3 0.3 0.052 13.5 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KFX95960.1 - 1.1e-09 38.5 0.9 0.00061 19.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFX95960.1 - 4.6e-09 35.6 0.4 0.0013 18.2 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KFX95960.1 - 3.3e-08 33.6 0.7 0.0001 22.2 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 KFX95960.1 - 3.1e-07 30.5 0.4 0.3 11.2 0.1 4.4 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KFX95960.1 - 4.2e-07 30.7 0.0 0.04 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFX95960.1 - 1.5e-06 27.8 2.7 0.33 10.5 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 KFX95960.1 - 6.1e-06 25.9 0.2 0.025 14.3 0.0 3.6 2 0 0 2 2 2 2 Part of AAA domain ABC_ATPase PF09818.4 KFX95960.1 - 1.3e-05 23.9 0.1 0.015 13.8 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KFX95960.1 - 2e-05 23.8 0.0 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX95960.1 - 3.7e-05 23.2 0.5 0.19 11.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 KFX95960.1 - 9.4e-05 21.9 0.4 0.11 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 KFX95960.1 - 0.00012 22.4 0.9 0.15 12.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX95960.1 - 0.00041 20.2 0.3 1.3 8.8 0.1 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFX95960.1 - 0.00061 19.6 0.2 1.2 9.0 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KFX95960.1 - 0.00063 20.0 0.1 1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFX95960.1 - 0.0015 18.7 1.1 8.9 6.5 0.2 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX95960.1 - 0.004 16.2 0.1 0.41 9.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 KFX95960.1 - 0.0044 16.5 0.0 0.058 12.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family PRK PF00485.13 KFX95960.1 - 0.0074 15.8 0.3 26 4.3 0.0 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KFX95960.1 - 0.013 15.4 0.1 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 KFX95960.1 - 0.014 15.0 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_5 PF07728.9 KFX95960.1 - 0.021 14.5 0.0 4.7 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 KFX95960.1 - 0.063 12.9 0.6 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 KFX95960.1 - 0.087 11.3 0.7 6.2 5.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) G-alpha PF00503.15 KFX95960.1 - 0.17 10.5 0.0 13 4.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit TIM PF00121.13 KFX95963.1 - 8.8e-89 296.7 0.6 9.9e-89 296.5 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DrsE PF02635.10 KFX95963.1 - 0.15 12.0 0.8 0.55 10.2 0.2 2.0 2 0 0 2 2 2 0 DsrE/DsrF-like family L51_S25_CI-B8 PF05047.11 KFX95964.1 - 9.6e-15 54.0 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 KFX95965.1 - 4e-31 107.1 2.1 4e-31 107.1 1.4 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KFX95965.1 - 2.8e-17 62.1 0.3 1.4e-16 59.8 0.2 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX95965.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX95965.1 - 9.3e-08 31.8 0.2 3.5e-07 29.9 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UreD PF01774.12 KFX95966.1 - 1.5e-56 191.2 0.0 1.8e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein B_lectin PF01453.19 KFX95966.1 - 0.005 16.7 0.5 0.011 15.6 0.4 1.5 1 0 0 1 1 1 1 D-mannose binding lectin DUF1155 PF06633.6 KFX95966.1 - 0.055 12.7 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) STAG PF08514.6 KFX95967.1 - 8.1e-25 86.8 0.2 2.5e-24 85.2 0.1 1.9 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KFX95967.1 - 1e-05 25.7 0.0 0.0012 19.0 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 KFX95967.1 - 0.013 15.5 0.1 20 5.6 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Methyltransf_23 PF13489.1 KFX95968.1 - 8e-15 54.9 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX95968.1 - 2.3e-06 28.1 0.1 2.6e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX95968.1 - 2.2e-05 24.8 0.0 4.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX95968.1 - 0.00016 21.3 0.0 0.0021 17.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX95968.1 - 0.00062 18.9 0.0 0.77 8.8 0.0 2.5 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 KFX95968.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 KFX95968.1 - 0.0017 18.8 0.0 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFX95968.1 - 0.0034 17.0 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.1 KFX95968.1 - 0.0061 16.8 0.0 0.019 15.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Peptidase_M17 PF00883.16 KFX95968.1 - 0.041 12.7 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain Methyltransf_26 PF13659.1 KFX95968.1 - 0.1 12.6 0.0 0.53 10.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Chromo PF00385.19 KFX95970.1 - 1.7e-16 59.6 4.4 8.6e-08 31.7 0.2 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_6 PF13921.1 KFX95970.1 - 1.5e-05 24.9 0.5 6.4e-05 22.9 0.4 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mtf2_C PF14061.1 KFX95970.1 - 0.14 12.0 0.8 6 6.8 0.0 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 OmpH PF03938.9 KFX95971.1 - 9.5 6.1 10.5 18 5.2 7.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PAH PF02671.16 KFX95973.1 - 1.1e-10 40.9 0.0 1.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat DUF3723 PF12520.3 KFX95974.1 - 4.4e-139 464.2 2.1 2e-125 419.2 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3723) CAF-1_p150 PF11600.3 KFX95974.1 - 0.054 12.8 25.6 0.1 11.9 17.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 KFX95974.1 - 2.7 7.8 8.5 4.2 7.1 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 KFX95974.1 - 6.9 6.4 13.4 14 5.4 9.3 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 KFX95975.1 - 3.7e-06 26.2 0.0 5.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95975.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_ligase_A_N PF04675.9 KFX95983.1 - 1.5e-10 41.2 0.0 2.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DUF4048 PF13257.1 KFX95984.1 - 1.1e-12 48.1 4.9 1.1e-12 48.1 3.4 4.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) Ribosomal_L29 PF00831.18 KFX95984.1 - 0.34 10.6 3.6 0.74 9.5 2.5 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein Tim17 PF02466.14 KFX95985.1 - 6.3e-48 162.0 7.4 6.3e-48 162.0 5.1 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family SKIP_SNW PF02731.10 KFX95986.1 - 7.9e-68 226.8 6.0 7.9e-68 226.8 4.2 2.4 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.19 KFX95986.1 - 7.5e-44 149.6 3.2 7.5e-44 149.6 2.3 1.7 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD DUF4603 PF15376.1 KFX95986.1 - 0.42 7.7 15.8 0.67 7.0 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FAM60A PF15396.1 KFX95986.1 - 5.5 6.6 9.2 14 5.3 6.4 1.7 1 0 0 1 1 1 0 Protein Family FAM60A USP7_ICP0_bdg PF12436.3 KFX95987.1 - 1.4e-77 260.3 0.5 2.2e-76 256.3 0.1 2.9 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KFX95987.1 - 2.1e-74 249.5 1.4 9.5e-71 237.5 0.4 3.2 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KFX95987.1 - 1.9e-54 184.5 2.6 3.1e-54 183.9 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX95987.1 - 2.5e-28 99.4 0.2 4.6e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFX95987.1 - 1.7e-12 47.6 0.9 3.6e-11 43.3 0.0 3.1 2 1 0 2 2 2 1 MATH domain YukD PF08817.5 KFX95987.1 - 0.016 15.7 0.0 0.076 13.5 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.4 KFX95988.1 - 2.6e-48 163.6 0.3 4.7e-48 162.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFX95988.1 - 3.4e-11 42.8 0.0 2e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFX95988.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KFX95988.1 - 0.076 12.8 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Septin PF00735.13 KFX95989.1 - 3e-115 384.0 0.1 3e-115 384.0 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFX95989.1 - 2.2e-07 30.8 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX95989.1 - 3.6e-06 26.5 0.1 7.9e-05 22.1 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFX95989.1 - 2e-05 23.8 0.0 5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KFX95989.1 - 0.0029 18.0 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KFX95989.1 - 0.0031 17.6 0.7 0.012 15.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KFX95989.1 - 0.0031 17.1 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 KFX95989.1 - 0.005 15.9 0.0 0.0084 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KFX95989.1 - 0.0066 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KFX95989.1 - 0.0081 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 KFX95989.1 - 0.013 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 KFX95989.1 - 0.025 13.9 0.4 0.072 12.4 0.2 1.8 1 1 0 1 1 1 0 Ras family T2SE PF00437.15 KFX95989.1 - 0.027 13.3 0.2 0.072 11.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 KFX95989.1 - 0.034 14.4 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KFX95989.1 - 0.043 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 KFX95989.1 - 0.053 13.3 5.1 0.88 9.3 0.0 2.8 2 1 1 3 3 3 0 Dynamin family Sigma54_activat PF00158.21 KFX95989.1 - 0.081 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFX95989.1 - 0.084 12.5 1.9 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase ArgK PF03308.11 KFX95989.1 - 0.089 11.5 1.8 0.81 8.4 0.0 2.6 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 KFX95989.1 - 0.089 12.2 0.6 2.9 7.3 0.2 2.6 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KFX95989.1 - 0.11 12.5 0.6 0.31 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 KFX95989.1 - 0.13 11.2 2.0 0.25 10.3 1.4 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KFX95989.1 - 0.15 11.5 0.6 9.3 5.7 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KFX95989.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.27 KFX95990.1 - 1.2e-53 177.1 30.4 1.1e-12 47.2 0.1 13.0 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 KFX95990.1 - 2.9e-28 97.9 0.0 4.5e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KFX95990.1 - 1.6e-07 31.2 3.5 0.053 13.2 0.1 6.1 6 2 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX95990.1 - 2.6e-05 22.5 2.7 0.32 9.0 0.1 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFX95990.1 - 0.014 14.5 0.1 1.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KFX95990.1 - 0.023 13.0 0.0 1.3 7.2 0.0 3.2 3 1 0 3 3 3 0 Cytochrome D1 heme domain TPR_11 PF13414.1 KFX95996.1 - 4.8e-35 119.0 5.7 6e-09 35.4 0.0 7.5 6 1 1 7 7 7 7 TPR repeat TPR_2 PF07719.12 KFX95996.1 - 1.8e-33 111.7 1.4 2.2e-05 23.9 0.0 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KFX95996.1 - 2.8e-31 107.4 5.9 7.3e-23 80.5 0.1 5.8 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFX95996.1 - 1.3e-28 97.3 0.0 9.5e-06 25.0 0.0 9.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFX95996.1 - 5.3e-25 87.1 5.2 5.9e-10 38.9 0.0 8.7 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX95996.1 - 6.4e-24 84.0 1.6 0.0033 17.7 0.0 8.7 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFX95996.1 - 7.4e-21 72.3 0.0 1.9e-05 24.0 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX95996.1 - 7.6e-20 71.0 0.5 1.7e-05 25.3 0.0 7.2 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX95996.1 - 3.9e-18 64.2 3.3 0.00022 21.5 0.0 9.7 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX95996.1 - 2.4e-17 61.2 2.0 2.2e-05 23.9 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFX95996.1 - 7.2e-15 54.3 0.9 1.1e-05 25.1 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX95996.1 - 2.4e-13 49.5 3.5 0.02 15.3 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFX95996.1 - 2.8e-09 36.5 0.3 0.0075 16.5 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX95996.1 - 1.4e-08 34.2 0.1 4.1 7.8 0.0 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX95996.1 - 1.7e-08 34.1 0.5 0.0083 15.9 0.0 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFX95996.1 - 0.00017 20.7 0.2 2.3 7.2 0.0 5.3 3 2 3 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 KFX95996.1 - 0.00047 19.9 4.9 0.071 13.1 0.1 4.4 4 0 0 4 4 4 1 PPR repeat DUF3856 PF12968.2 KFX95996.1 - 0.0017 18.2 0.7 0.11 12.3 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) RPN7 PF10602.4 KFX95996.1 - 0.0025 17.2 0.7 0.59 9.4 0.0 4.0 3 2 0 4 4 4 1 26S proteasome subunit RPN7 MIT PF04212.13 KFX95996.1 - 0.17 11.7 1.5 23 4.9 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 KFX95996.1 - 0.75 9.7 10.2 3.1 7.7 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_L27 PF01016.14 KFX95997.1 - 1.2e-29 101.8 0.1 2.5e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein tRNA-synt_1c PF00749.16 KFX95999.1 - 1.3e-101 339.3 0.1 1.7e-101 339.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFX95999.1 - 1e-39 136.0 0.1 1.8e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KFX95999.1 - 0.016 14.3 0.5 0.045 12.8 0.2 1.6 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 KFX96000.1 - 1.1e-31 109.8 0.0 1.6e-31 109.4 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Phage_tail_S PF05069.8 KFX96000.1 - 0.093 12.5 2.3 0.17 11.6 1.6 1.4 1 0 0 1 1 1 0 Phage virion morphogenesis family COG2 PF06148.6 KFX96001.1 - 2.6e-29 101.7 0.8 4.3e-29 101.0 0.6 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KFX96001.1 - 1.5e-05 24.7 0.4 0.00041 20.1 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.6 KFX96001.1 - 0.00086 18.0 0.4 0.0013 17.4 0.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.16 KFX96001.1 - 0.033 13.6 0.5 0.053 12.9 0.3 1.3 1 0 0 1 1 1 0 Intermediate filament protein COG5 PF10392.4 KFX96001.1 - 0.042 13.8 0.2 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 DUF3287 PF11690.3 KFX96001.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) AlkA_N PF06029.6 KFX96001.1 - 0.17 11.9 1.1 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 AlkA N-terminal domain IncA PF04156.9 KFX96001.1 - 0.19 11.3 5.9 13 5.2 4.2 2.3 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 KFX96001.1 - 0.23 11.4 1.8 3.9 7.5 0.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Hap4_Hap_bind PF10297.4 KFX96002.1 - 3e-06 26.8 9.8 3e-06 26.8 6.8 3.4 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 ERM PF00769.14 KFX96002.1 - 1.2e-05 25.0 7.2 1.9e-05 24.3 5.0 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Atg14 PF10186.4 KFX96002.1 - 4.5e-05 22.5 1.6 7e-05 21.9 1.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 KFX96002.1 - 9.9e-05 22.2 13.0 9.9e-05 22.2 9.0 2.6 2 1 0 3 3 3 1 bZIP transcription factor RRN3 PF05327.6 KFX96002.1 - 0.09 10.8 0.2 0.12 10.4 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_UL25 PF01499.11 KFX96002.1 - 7.1 4.8 7.9 11 4.1 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Acyl-CoA_dh_2 PF08028.6 KFX96002.1 - 7.9 6.7 8.2 14 5.8 5.7 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_11 PF13414.1 KFX96003.1 - 3.5e-09 36.1 0.0 1.5e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KFX96003.1 - 0.00015 21.4 0.0 0.17 11.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.26 KFX96003.1 - 0.00021 21.0 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.26 KFX96003.1 - 0.007 16.0 0.0 0.03 14.0 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 KFX96003.1 - 0.019 14.9 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX96003.1 - 0.12 12.0 0.0 2.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Adenylate_cycl PF01295.13 KFX96003.1 - 0.26 9.5 1.3 0.56 8.4 0.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase, class-I PhoD PF09423.5 KFX96004.1 - 3.3e-52 177.5 0.0 5e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase SGS PF05002.10 KFX96004.1 - 8.9e-31 105.4 0.7 2e-30 104.3 0.5 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KFX96004.1 - 1.7e-18 66.9 0.1 3.4e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KFX96004.1 - 5e-07 29.2 2.6 1e-06 28.2 1.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFX96004.1 - 0.0029 17.4 4.8 3.1 7.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX96004.1 - 0.011 15.3 3.7 1.8 8.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX96004.1 - 0.018 15.4 0.3 0.89 9.9 0.1 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat CtaG_Cox11 PF04442.9 KFX96004.1 - 0.036 13.8 0.2 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 TPR_16 PF13432.1 KFX96004.1 - 0.09 13.4 6.0 0.44 11.2 2.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KFX96005.1 - 2.9e-70 236.3 0.0 4.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96005.1 - 2.4e-46 157.9 0.0 5.6e-46 156.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96005.1 - 1.4e-05 24.2 0.0 6.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like hNIFK_binding PF12196.3 KFX96005.1 - 0.16 11.3 1.3 0.43 10.0 0.9 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK YABBY PF04690.8 KFX96005.1 - 0.37 11.0 2.8 0.21 11.8 0.3 1.7 2 0 0 2 2 2 0 YABBY protein Transglut_core PF01841.14 KFX96006.1 - 2.2e-12 47.1 0.1 7.1e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KFX96006.1 - 3.6e-09 35.9 0.2 1.7e-08 33.7 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFX96006.1 - 3e-06 26.4 0.0 1.3e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX96006.1 - 7.1e-05 22.3 0.0 0.0002 20.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core2 PF13369.1 KFX96006.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily UQ_con PF00179.21 KFX96007.1 - 4.9e-51 171.8 0.0 5.5e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NMT1 PF09084.6 KFX96008.1 - 1.8e-06 27.7 0.0 3.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 KFX96008.1 - 0.0029 16.8 0.0 0.22 10.7 0.0 2.6 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.1 KFX96008.1 - 0.033 13.8 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein LysR_substrate PF03466.15 KFX96008.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain ATP-synt_ab PF00006.20 KFX96009.1 - 2.6e-113 376.8 0.0 4e-113 376.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFX96009.1 - 2.2e-19 69.9 0.3 4.4e-19 69.0 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFX96009.1 - 2.7e-15 56.3 4.5 8.7e-15 54.6 3.3 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain WD40 PF00400.27 KFX96010.1 - 6.9e-33 111.3 13.4 3.8e-08 32.9 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX96010.1 - 7.4e-05 22.5 0.2 0.15 11.7 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 KFX96010.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 KFX96010.1 - 0.0038 16.8 0.0 16 5.2 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat PfkB PF00294.19 KFX96011.1 - 3e-48 164.5 1.0 3.7e-48 164.1 0.7 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Dynamin_M PF01031.15 KFX96012.1 - 1.3e-105 352.3 1.5 4.3e-105 350.7 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFX96012.1 - 1.4e-55 187.6 0.0 2.6e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFX96012.1 - 8.4e-30 102.5 6.1 1.8e-29 101.4 4.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX96012.1 - 0.00096 19.0 1.4 0.01 15.7 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFX96012.1 - 0.0034 17.8 0.0 0.034 14.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein CoA_transf_3 PF02515.12 KFX96013.1 - 7.9e-52 175.2 0.0 1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Exo_endo_phos PF03372.18 KFX96014.1 - 2e-24 86.9 0.3 3.4e-24 86.1 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 KFX96014.1 - 0.025 14.3 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1572 PF07609.6 KFX96014.1 - 0.095 12.2 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) APC_CDC26 PF10471.4 KFX96015.1 - 0.044 14.5 0.8 0.066 13.9 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 CTD_bind PF04818.8 KFX96016.1 - 1.2e-08 35.0 0.2 3.2e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF605 PF04652.11 KFX96016.1 - 0.00034 20.1 17.2 0.00058 19.3 11.9 1.3 1 0 0 1 1 1 1 Vta1 like DUF1777 PF08648.7 KFX96016.1 - 0.0049 16.6 27.0 0.0085 15.8 18.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Transformer PF06495.6 KFX96016.1 - 0.72 9.7 33.9 0.19 11.5 21.2 1.7 2 0 0 2 2 2 0 Fruit fly transformer protein PRP38_assoc PF12871.2 KFX96016.1 - 3.7 8.1 33.5 11 6.6 23.2 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF2956 PF11169.3 KFX96020.1 - 8.9 6.3 7.7 3.5 7.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Spc97_Spc98 PF04130.8 KFX96021.1 - 3.8e-59 200.4 0.2 5.8e-59 199.8 0.2 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KFX96021.1 - 0.0002 19.6 0.0 0.00051 18.3 0.0 1.7 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 KFX96022.1 - 3.8e-133 443.5 8.1 5.5e-133 442.9 5.6 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Aminotran_1_2 PF00155.16 KFX96022.1 - 4.3e-13 48.9 0.0 1.7e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.6 KFX96022.1 - 0.0043 15.8 0.0 0.008 14.9 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase MTHFR PF02219.12 KFX96023.1 - 6.1e-103 343.8 0.0 8.7e-103 343.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Cdc6_C PF09079.6 KFX96028.1 - 0.042 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal VHS PF00790.14 KFX96037.1 - 5.8e-33 113.4 1.6 1.1e-32 112.5 1.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 KFX96037.1 - 4.4e-16 58.0 0.0 8.9e-16 57.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX96037.1 - 9.3e-16 57.1 0.1 1.7e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX96037.1 - 2.1e-14 52.7 0.0 3.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KFX96037.1 - 0.025 14.1 0.7 0.067 12.7 0.5 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Cyt-b5 PF00173.23 KFX96038.1 - 2.4e-24 84.9 0.1 3e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.12 KFX96039.1 - 2.1e-93 312.2 0.0 2.4e-93 312.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Phage_connect_1 PF05135.8 KFX96039.1 - 0.077 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein MBA1 PF07961.6 KFX96049.1 - 3.3e-18 65.3 0.0 4.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 KFX96049.1 - 6.6e-07 29.4 0.3 1.5e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 Tim44-like domain SSF PF00474.12 KFX96050.1 - 1.3e-05 24.0 31.3 0.00011 21.0 21.7 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 KFX96051.1 - 2.1e-25 88.1 0.8 7.8e-12 44.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX96051.1 - 3.7e-15 55.6 0.5 2.5e-08 33.7 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX96051.1 - 5.9e-14 51.6 0.6 2.5e-06 27.2 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX96051.1 - 0.0017 18.0 0.1 0.29 10.9 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif TRAP_alpha PF03896.11 KFX96051.1 - 0.095 11.6 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRM_3 PF08777.6 KFX96051.1 - 0.099 12.5 0.1 2.6 7.9 0.0 2.9 3 1 0 3 3 3 0 RNA binding motif CIA30 PF08547.7 KFX96052.1 - 1.6e-41 141.7 0.0 2.7e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Apc5 PF12862.2 KFX96052.1 - 2.3e-34 117.0 2.2 6.6e-34 115.6 1.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 PMAIP1 PF15150.1 KFX96052.1 - 0.03 14.0 0.2 0.083 12.6 0.1 1.8 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced TPR_2 PF07719.12 KFX96052.1 - 2.1 8.4 4.4 14 5.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat COX6A PF02046.10 KFX96053.1 - 6.1e-45 151.8 2.3 6.4e-45 151.8 1.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PSK_trans_fac PF07704.6 KFX96053.1 - 0.13 12.9 2.5 0.21 12.2 1.7 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor Exo_endo_phos PF03372.18 KFX96054.1 - 1.2e-18 68.0 0.0 1.8e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFX96054.1 - 6.5e-15 54.7 0.0 3e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KFX96054.1 - 0.00027 20.7 1.4 0.00078 19.3 1.0 1.8 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 KFX96055.1 - 7.3e-21 74.2 0.4 1.2e-20 73.5 0.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX96055.1 - 0.042 14.2 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Peripla_BP_1 PF00532.16 KFX96056.1 - 0.057 12.6 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family ANTH PF07651.11 KFX96057.1 - 5.9e-79 264.6 0.0 5.9e-79 264.6 0.0 2.4 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KFX96057.1 - 4.8e-64 214.9 6.2 4.8e-64 214.9 4.3 5.7 5 1 0 6 6 6 2 I/LWEQ domain Med15 PF09606.5 KFX96057.1 - 5 5.2 37.9 12 3.9 26.3 1.6 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_pol_B PF00136.16 KFX96058.1 - 7.5e-89 298.6 0.0 1.4e-88 297.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DUF2404 PF10296.4 KFX96058.1 - 4.3e-29 100.4 0.0 1e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DNA_pol_B_exo1 PF03104.14 KFX96058.1 - 5.1e-23 81.4 0.1 1.7e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFX96058.1 - 8.1e-18 64.1 5.9 2e-17 62.9 4.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 KFX96058.1 - 7.9 6.3 4.8 7.1 6.5 0.8 1.7 1 1 1 2 2 2 0 Double zinc ribbon Slu7 PF11708.3 KFX96059.1 - 1.2e-76 257.6 16.4 1.2e-76 257.6 11.4 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KFX96059.1 - 0.0092 15.6 1.1 0.016 14.8 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_S4 PF00163.14 KFX96060.1 - 6.9e-30 103.2 1.2 1.4e-29 102.3 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KFX96060.1 - 2.6e-12 45.9 1.3 2.6e-12 45.9 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 KFX96061.1 - 2.2e-40 136.4 6.6 1.3e-38 130.7 3.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L21e Sec2p PF06428.6 KFX96062.1 - 6e-22 77.3 16.2 6e-22 77.3 11.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 KFX96062.1 - 0.12 10.2 8.3 0.18 9.6 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Methyltransf_21 PF05050.7 KFX96062.1 - 0.12 12.2 0.4 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase FkbM domain DUF310 PF03750.8 KFX96062.1 - 0.86 9.8 6.2 2.4 8.3 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF4407 PF14362.1 KFX96062.1 - 1.8 7.4 9.2 3.8 6.3 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alg6_Alg8 PF03155.10 KFX96064.1 - 2.4e-122 409.1 19.9 2.8e-122 408.9 13.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 KFX96065.1 - 7.8e-21 74.2 0.0 1.3e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family IncA PF04156.9 KFX96065.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 IncA protein DUF2937 PF11157.3 KFX96065.1 - 0.11 11.7 2.6 0.21 10.9 1.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) HalX PF08663.5 KFX96065.1 - 0.13 12.2 0.3 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 HalX domain DUF812 PF05667.6 KFX96065.1 - 0.17 10.3 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 KFX96065.1 - 0.19 9.0 0.1 0.25 8.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RVT_2 PF07727.9 KFX96087.1 - 1.1e-76 257.0 0.0 1.5e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Brevenin PF03032.10 KFX96087.1 - 3 7.7 4.3 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family rve PF00665.21 KFX96088.1 - 4.3e-14 52.6 0.4 9.1e-14 51.6 0.3 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 KFX96088.1 - 9.6e-12 44.7 0.2 2.3e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KFX96088.1 - 1.5e-08 34.1 0.0 3.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 KFX96088.1 - 2.9e-08 33.2 0.1 6.7e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Kdo PF06293.9 KFX96100.1 - 2.5e-10 39.7 0.0 5.3e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX96100.1 - 1.1e-09 38.4 0.3 0.00014 21.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFX96100.1 - 4.1e-09 35.9 0.0 4.5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96100.1 - 6.6e-05 22.1 0.0 9.3e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFX96100.1 - 0.00038 19.8 0.0 0.0009 18.6 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFX96100.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 KFX96101.1 - 7.4e-10 38.1 0.0 9.8e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 KFX96102.1 - 1.2e-52 177.4 1.3 1.4e-52 177.1 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 KFX96103.1 - 1.2e-56 191.3 0.0 1.7e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Cwf_Cwc_15 PF04889.7 KFX96103.1 - 0.44 10.2 9.7 0.59 9.8 6.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.21 KFX96104.1 - 4.8e-26 90.0 0.1 5.7e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFX96104.1 - 0.00027 20.8 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KFX96104.1 - 0.06 13.1 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain ATP-synt_C PF00137.16 KFX96105.1 - 8.2e-32 108.9 29.0 7.9e-19 67.3 8.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 KFX96105.1 - 0.23 10.5 1.0 2.7 7.1 0.1 2.0 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2970 PF11174.3 KFX96105.1 - 6 6.5 10.1 0.64 9.6 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CMD PF02627.15 KFX96106.1 - 3.6e-10 39.5 0.2 3.2e-08 33.3 0.0 2.5 3 0 0 3 3 3 2 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.16 KFX96108.1 - 2.9e-08 33.5 8.1 5.3e-08 32.7 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX96108.1 - 0.0054 16.5 7.8 0.0054 16.5 5.4 1.6 2 0 0 2 2 2 1 Basic region leucine zipper V_ATPase_I PF01496.14 KFX96108.1 - 0.015 13.2 1.0 0.016 13.0 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.12 KFX96108.1 - 0.11 12.8 9.1 0.23 11.8 6.3 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor eIF-3c_N PF05470.7 KFX96108.1 - 0.14 10.2 3.6 0.17 9.9 2.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ATG16 PF08614.6 KFX96108.1 - 0.25 11.1 7.3 0.2 11.4 3.9 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 KFX96108.1 - 0.31 10.0 5.0 0.44 9.5 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 KFX96108.1 - 0.31 10.1 6.6 0.56 9.3 4.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KFX96108.1 - 0.33 10.5 6.8 0.52 9.8 4.7 1.2 1 0 0 1 1 1 0 IncA protein Tom37_C PF11801.3 KFX96108.1 - 0.7 9.7 8.9 0.33 10.8 4.3 1.6 1 1 1 2 2 2 0 Tom37 C-terminal domain DUF972 PF06156.8 KFX96108.1 - 0.82 10.0 3.8 1.3 9.4 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) M PF02370.11 KFX96108.1 - 2.9 8.5 6.7 2.9 8.5 0.3 2.9 2 1 0 2 2 2 0 M protein repeat Med9 PF07544.8 KFX96109.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.6 KFX96110.1 - 0.035 14.0 0.3 0.035 14.0 0.2 7.1 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KFX96110.1 - 0.062 12.4 14.7 0.12 11.5 3.6 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KFX96110.1 - 0.069 13.4 9.5 6.8 7.0 0.3 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.13 KFX96110.1 - 0.23 11.1 0.1 0.23 11.1 0.1 5.7 8 0 0 8 8 8 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 KFX96110.1 - 3.8 7.6 32.9 0.028 14.5 4.5 4.1 3 1 0 4 4 4 0 Fibrinogen alpha/beta chain family Filament PF00038.16 KFX96110.1 - 5.7 6.3 56.6 0.017 14.6 19.6 4.8 2 1 2 4 4 4 0 Intermediate filament protein zf-C2H2_4 PF13894.1 KFX96111.1 - 6e-06 26.2 12.7 0.27 11.6 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX96111.1 - 0.00016 21.7 13.9 0.3 11.5 2.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type APG6 PF04111.7 KFX96111.1 - 0.012 14.6 10.6 0.017 14.1 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-H2C2_2 PF13465.1 KFX96111.1 - 0.013 15.8 18.5 0.86 10.0 0.4 3.8 3 0 0 3 3 3 0 Zinc-finger double domain FlxA PF14282.1 KFX96111.1 - 0.34 10.8 14.5 0.6 10.0 10.0 1.3 1 0 0 1 1 1 0 FlxA-like protein DivIVA PF05103.8 KFX96111.1 - 0.69 9.9 10.9 1.5 8.9 7.6 1.5 1 0 0 1 1 1 0 DivIVA protein Atg14 PF10186.4 KFX96111.1 - 0.9 8.4 6.3 1.3 7.9 4.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFX96111.1 - 1.4 6.6 6.2 1.6 6.5 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.7 KFX96111.1 - 1.4 9.1 8.3 3.3 7.9 5.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ADIP PF11559.3 KFX96111.1 - 1.6 8.6 13.9 3.2 7.6 9.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS6_N PF14661.1 KFX96111.1 - 8.9 5.5 10.9 15 4.8 7.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc24 PF08286.6 KFX96111.1 - 8.9 6.0 8.4 20 4.9 5.8 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2968 PF11180.3 KFX96111.1 - 9.3 5.5 17.3 0.33 10.3 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF3115 PF11312.3 KFX96112.1 - 9.9e-84 280.8 0.0 1.2e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Syja_N PF02383.13 KFX96113.1 - 4.1e-94 314.9 0.0 5.8e-94 314.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KFX96113.1 - 1.1e-29 102.1 0.0 1.9e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HATPase_c PF02518.21 KFX96114.1 - 2.6e-26 91.5 0.0 7.9e-26 89.9 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX96114.1 - 4.6e-26 91.0 0.2 8.3e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFX96114.1 - 2.2e-13 49.9 0.0 5.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KFX96114.1 - 0.047 13.8 6.0 0.1 12.7 0.0 2.9 3 0 0 3 3 3 0 HAMP domain DUF1349 PF07081.6 KFX96116.1 - 2.8e-24 85.5 0.0 3.6e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Glyco_hydro_72 PF03198.9 KFX96117.1 - 2.6e-129 430.7 0.2 3.2e-129 430.4 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFX96117.1 - 0.00026 20.3 0.0 0.002 17.3 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SH3_9 PF14604.1 KFX96118.1 - 5.7e-25 86.6 1.1 6.3e-15 54.4 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFX96118.1 - 1.5e-18 65.8 0.4 3.3e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KFX96118.1 - 3.8e-09 35.8 0.1 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KFX96118.1 - 4e-07 30.1 1.5 4.7e-05 23.4 0.4 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain GST_N_2 PF13409.1 KFX96128.1 - 2.2e-10 40.3 0.0 4.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KFX96128.1 - 3.1e-10 40.1 0.0 6.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX96128.1 - 3.7e-08 33.4 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX96128.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX96128.1 - 0.00089 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_47 PF01532.15 KFX96129.1 - 3.5e-132 441.2 0.0 4.2e-132 441.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KFX96129.1 - 0.013 15.2 0.0 0.063 12.9 0.0 2.0 2 0 0 2 2 2 0 PA domain Zip PF02535.17 KFX96130.1 - 7.5e-47 159.8 5.1 1.3e-46 159.0 3.5 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter ER_lumen_recept PF00810.13 KFX96131.1 - 1.6e-32 113.0 10.2 1.6e-32 113.0 7.1 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KFX96131.1 - 0.098 12.2 7.1 0.23 11.0 0.0 2.8 3 0 0 3 3 3 0 PQ loop repeat 7TMR-DISM_7TM PF07695.6 KFX96131.1 - 0.15 11.6 12.3 0.049 13.2 6.5 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling HlyIII PF03006.15 KFX96131.1 - 0.49 9.7 11.2 1.4 8.2 1.8 2.3 1 1 1 2 2 2 0 Haemolysin-III related CN_hydrolase PF00795.17 KFX96134.1 - 1.4e-15 57.1 0.0 2.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF824 PF05688.6 KFX96141.1 - 0.097 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Fungal_trans PF04082.13 KFX96142.1 - 3e-15 55.8 0.0 1.3e-14 53.7 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain NAD_binding_6 PF08030.7 KFX96144.1 - 1.5e-20 73.7 0.0 1e-12 48.2 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX96144.1 - 3.9e-16 58.8 0.0 8.7e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ctr PF04145.10 KFX96145.1 - 4.3e-23 81.9 0.0 5e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Papilloma_E5A PF05776.7 KFX96145.1 - 0.048 13.8 1.6 0.6 10.2 0.1 2.1 2 0 0 2 2 2 0 Papillomavirus E5A protein Abhydrolase_3 PF07859.8 KFX96146.1 - 1.9e-07 30.8 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold TUG-UBL1 PF11470.3 KFX96179.1 - 2.1e-18 66.0 0.0 6.2e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 KFX96179.1 - 1.7e-07 31.1 0.3 0.04 13.9 0.0 3.3 3 1 1 4 4 4 2 UBX domain FERM_N PF09379.5 KFX96179.1 - 0.03 14.3 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain PAS_7 PF12860.2 KFX96179.1 - 0.075 13.0 0.2 6 6.9 0.0 2.4 2 0 0 2 2 2 0 PAS fold Ribosomal_L36e PF01158.13 KFX96180.1 - 3.5e-38 129.5 5.3 5e-38 129.0 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 KFX96180.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 LemA family DAGAT PF03982.8 KFX96180.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol acyltransferase IF-2B PF01008.12 KFX96181.1 - 8.6e-73 244.7 0.0 1.4e-72 244.0 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family eIF-3c_N PF05470.7 KFX96181.1 - 0.024 12.7 0.1 0.034 12.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA PF00004.24 KFX96182.1 - 7.8e-10 39.0 0.0 1.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX96182.1 - 5.2e-09 36.3 0.0 7e-08 32.6 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFX96182.1 - 5.6e-09 36.2 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KFX96182.1 - 4.1e-05 23.2 0.1 0.00018 21.1 0.0 2.0 1 1 0 1 1 1 1 CDC6, C terminal NACHT PF05729.7 KFX96182.1 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KFX96182.1 - 0.0038 16.9 2.2 0.0066 16.1 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KFX96182.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFX96182.1 - 0.063 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KFX96182.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KFX96182.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KFX96182.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WW PF00397.21 KFX96183.1 - 3.6e-09 36.3 0.1 9.7e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KFX96183.1 - 0.0066 15.0 0.7 0.017 13.6 0.4 1.6 2 0 0 2 2 2 1 PhoD-like phosphatase PMM PF03332.8 KFX96184.1 - 4.7e-104 346.7 0.2 5.2e-104 346.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMPIT PF07851.8 KFX96184.1 - 0.022 13.8 0.1 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein adh_short PF00106.20 KFX96191.1 - 7.3e-13 48.7 0.1 1.2e-12 48.0 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX96191.1 - 3.1e-06 26.9 0.0 5.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KFX96191.1 - 0.00012 22.0 0.7 0.0011 18.9 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain NmrA PF05368.8 KFX96191.1 - 0.00082 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 KFX96191.1 - 0.0035 17.1 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 KFX96191.1 - 0.01 14.7 0.0 0.96 8.3 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.1 KFX96191.1 - 0.014 15.4 0.0 0.094 12.7 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 KFX96191.1 - 0.018 14.4 0.1 0.026 13.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX96191.1 - 0.097 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans_2 PF11951.3 KFX96192.1 - 3.1e-37 128.0 3.8 8.1e-37 126.7 2.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96192.1 - 5e-07 29.5 8.5 8.5e-07 28.7 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_protease_2 PF13650.1 KFX96193.1 - 0.017 15.5 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Spore_YabQ PF09578.5 KFX96194.1 - 0.054 13.4 0.5 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) DUF4407 PF14362.1 KFX96194.1 - 0.19 10.6 4.0 0.82 8.5 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3159 PF11361.3 KFX96194.1 - 0.31 10.5 4.8 0.44 9.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) EamA PF00892.15 KFX96194.1 - 0.96 9.4 9.0 0.14 12.2 2.8 2.1 3 0 0 3 3 3 0 EamA-like transporter family Peptidase_S28 PF05577.7 KFX96204.1 - 3.5e-48 164.2 0.0 2e-47 161.7 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 KFX96204.1 - 0.00014 20.4 0.3 0.22 9.9 0.0 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 DUF4490 PF14892.1 KFX96204.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) Activin_recp PF01064.18 KFX96205.1 - 0.027 15.1 9.0 0.029 15.0 3.5 2.6 2 1 1 3 3 3 0 Activin types I and II receptor domain Lamp PF01299.12 KFX96205.1 - 0.11 11.5 0.8 0.21 10.6 0.0 1.7 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) TPR_12 PF13424.1 KFX96208.1 - 1.2e-54 182.1 25.1 1.2e-10 41.1 0.1 7.0 2 1 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 KFX96208.1 - 3.1e-48 160.4 5.9 7.1e-07 28.9 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat NB-ARC PF00931.17 KFX96208.1 - 6.4e-09 35.0 0.0 1.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 KFX96208.1 - 1.1e-06 29.1 12.0 0.087 13.5 0.0 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX96208.1 - 8.7e-06 25.1 11.7 0.91 9.4 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX96208.1 - 0.0001 21.8 8.2 4.9 6.8 0.0 5.4 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 KFX96208.1 - 0.00018 21.1 9.5 3.2 7.8 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX96208.1 - 0.00052 20.0 0.0 4.6 7.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 KFX96208.1 - 0.00088 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KFX96208.1 - 0.0021 18.2 0.0 0.0082 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX96208.1 - 0.0026 17.7 0.0 0.008 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TPR_4 PF07721.9 KFX96208.1 - 0.012 15.9 1.6 5.7 7.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX96208.1 - 0.03 13.9 11.3 19 5.0 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.13 KFX96209.1 - 1.7e-36 125.3 0.0 4.8e-36 123.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFX96209.1 - 7.3e-17 61.3 0.0 2.2e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX96209.1 - 9.3e-14 51.3 0.0 1.4e-12 47.5 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Gly_transf_sug PF04488.10 KFX96210.1 - 1.6e-06 28.4 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFX96210.1 - 0.027 12.9 0.0 0.093 11.2 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Antimicrobial10 PF08105.6 KFX96210.1 - 0.052 13.1 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Metchnikowin family DUF3016 PF11454.3 KFX96212.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DUF899 PF05988.7 KFX96215.1 - 6e-78 261.1 0.0 7e-78 260.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 KFX96215.1 - 0.003 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF500 PF04366.7 KFX96216.1 - 2.4e-45 153.0 0.2 5.4e-45 151.8 0.2 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_2 PF07653.12 KFX96216.1 - 9.3e-15 53.8 0.1 3.7e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFX96216.1 - 1.3e-14 53.2 0.2 4.8e-14 51.4 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFX96216.1 - 1.7e-13 49.9 0.1 3.3e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3262 PF11660.3 KFX96217.1 - 0.038 14.0 1.3 0.071 13.2 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Synaptobrevin PF00957.16 KFX96217.1 - 0.055 13.0 0.3 2.3 7.8 0.0 2.0 1 1 1 2 2 2 0 Synaptobrevin SNARE PF05739.14 KFX96217.1 - 0.06 13.0 0.0 0.091 12.4 0.0 1.3 1 1 0 1 1 1 0 SNARE domain Zn_clus PF00172.13 KFX96221.1 - 3.8e-07 29.8 9.7 6.6e-07 29.1 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX96221.1 - 1.1e-06 27.5 0.2 1.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 KFX96226.1 - 0.00044 20.1 0.1 0.00049 20.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PigN PF04987.9 KFX96228.1 - 2.9e-161 537.0 24.3 4.5e-161 536.4 16.8 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.3 KFX96228.1 - 4.5e-27 94.3 0.1 1.1e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.17 KFX96228.1 - 1.6e-10 40.9 5.7 4.6e-10 39.3 0.7 3.0 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX96228.1 - 1.7e-07 30.7 0.0 3.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Lebercilin PF15619.1 KFX96228.1 - 0.0018 17.7 29.4 0.0018 17.7 20.3 2.3 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Mitofilin PF09731.4 KFX96228.1 - 0.057 12.0 45.3 0.093 11.3 31.4 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Reo_sigmaC PF04582.7 KFX96228.1 - 0.53 9.4 7.9 1.1 8.3 5.5 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFX96228.1 - 3.5 5.9 25.5 7.3 4.9 17.7 1.5 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFX96228.1 - 4.5 6.8 38.2 3.1 7.3 21.6 3.0 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 KFX96228.1 - 6.2 7.1 11.4 4.2 7.6 1.7 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein QCR10 PF09796.4 KFX96232.1 - 7.7e-29 99.1 0.7 9.9e-29 98.7 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) U-box PF04564.10 KFX96233.1 - 1.7e-20 72.7 0.0 3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KFX96233.1 - 1.1e-18 66.6 4.7 1.1e-16 60.2 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFX96233.1 - 7.2e-07 28.5 4.7 0.0036 16.8 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX96233.1 - 2.7e-05 23.7 5.9 0.0046 16.7 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX96233.1 - 9.6e-05 22.9 3.8 0.00045 20.8 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX96233.1 - 0.0041 17.1 0.3 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX96233.1 - 0.045 13.6 4.8 3.6 7.6 0.7 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFX96233.1 - 0.085 12.7 2.3 0.12 12.1 0.2 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Rabaptin PF03528.10 KFX96233.1 - 0.089 12.7 4.3 0.18 11.6 3.0 1.5 1 0 0 1 1 1 0 Rabaptin zf-Nse PF11789.3 KFX96233.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit TPR_14 PF13428.1 KFX96233.1 - 0.1 13.2 0.5 0.1 13.2 0.3 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat Pinin_SDK_memA PF04696.8 KFX96233.1 - 0.17 11.4 3.8 0.23 11.0 1.6 1.9 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region TPR_19 PF14559.1 KFX96233.1 - 1.5 9.2 5.2 2.1 8.7 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat LUC7 PF03194.10 KFX96233.1 - 3.6 7.0 6.6 14 5.0 0.1 2.1 1 1 1 2 2 2 0 LUC7 N_terminus ADH_zinc_N PF00107.21 KFX96235.1 - 1.3e-23 82.9 0.3 2.5e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX96235.1 - 1.7e-12 48.3 0.1 3.8e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX96235.1 - 6.4e-08 32.3 0.0 1.6e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_7 PF00840.15 KFX96236.1 - 2.3e-151 504.0 3.4 2.8e-151 503.7 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Peptidase_S58 PF03576.9 KFX96237.1 - 1.8e-99 333.0 2.0 2.2e-99 332.7 1.4 1.0 1 0 0 1 1 1 1 Peptidase family S58 Transferase PF02458.10 KFX96238.1 - 9.9e-43 146.1 0.0 6e-24 84.2 0.0 3.1 3 0 0 3 3 3 3 Transferase family Flavin_Reduct PF01613.13 KFX96239.1 - 1.8e-12 47.4 0.0 2.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KFX96239.1 - 0.0001 21.9 0.3 0.00054 19.5 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 KFX96239.1 - 0.072 13.1 0.1 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ADH_N PF08240.7 KFX96240.1 - 2.8e-10 39.9 0.0 6.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX96240.1 - 1.1e-09 37.9 0.0 1.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KFX96240.1 - 0.026 13.9 0.1 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 KFX96241.1 - 1.2e-06 28.2 9.8 1.2e-06 28.2 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2 PF00703.16 KFX96242.1 - 1.8e-11 44.4 2.2 2.1e-10 40.9 0.1 3.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFX96242.1 - 6.6e-09 35.5 0.1 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain CARDB PF07705.6 KFX96242.1 - 0.47 10.5 6.9 0.48 10.4 0.9 3.2 4 0 0 4 4 4 0 CARDB AA_permease_2 PF13520.1 KFX96243.1 - 1.8e-47 161.8 57.8 2.1e-47 161.6 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX96243.1 - 2.3e-22 79.0 47.3 3e-22 78.6 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease Gly_transf_sug PF04488.10 KFX96244.1 - 7.6e-10 39.1 0.1 1.7e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif L_HGMIC_fpl PF10242.4 KFX96244.1 - 0.0026 17.8 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Hexokinase_2 PF03727.11 KFX96245.1 - 3.8e-57 193.2 0.0 9.5e-45 152.6 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 KFX96245.1 - 1e-56 191.5 0.0 1.4e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Zn_clus PF00172.13 KFX96246.1 - 6e-06 26.0 8.5 1.1e-05 25.2 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHBC_N PF12551.3 KFX96246.1 - 0.059 12.9 1.8 0.13 11.8 0.2 2.3 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal Cutinase PF01083.17 KFX96247.1 - 1.2e-52 178.2 2.1 1.4e-52 178.0 1.4 1.0 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 KFX96247.1 - 0.00017 21.8 0.1 0.00024 21.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 KFX96247.1 - 0.00027 20.5 0.1 0.00039 20.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFX96247.1 - 0.00059 19.4 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 KFX96247.1 - 0.0012 18.3 0.1 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 KFX96247.1 - 0.0026 17.1 0.1 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KFX96247.1 - 0.0059 16.3 0.6 0.0076 16.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 KFX96247.1 - 0.034 13.9 0.0 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 KFX96247.1 - 0.1 12.4 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFX96247.1 - 0.11 12.0 0.3 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.2 KFX96248.1 - 2.5e-05 23.9 0.2 0.00013 21.6 0.2 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX96248.1 - 0.0068 16.0 2.8 0.013 15.1 0.6 2.6 3 0 0 3 3 3 1 F-box domain Uteroglobin PF01099.12 KFX96248.1 - 0.035 13.9 0.3 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Uteroglobin family DASH_Duo1 PF08651.5 KFX96248.1 - 0.053 13.1 0.1 2.4 7.8 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF2666 PF10869.3 KFX96248.1 - 0.11 12.5 0.5 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2666) MFS_1 PF07690.11 KFX96249.1 - 2.4e-34 118.5 34.3 3.7e-34 117.9 23.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.23 KFX96250.1 - 5.8e-81 272.8 0.3 8.3e-81 272.2 0.2 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX96250.1 - 4.2e-08 33.0 0.2 3.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX96250.1 - 0.0018 17.0 0.0 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 KFX96251.1 - 3.7e-09 35.8 0.3 5.8e-09 35.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 KFX96252.1 - 6.9e-36 123.6 0.8 8.6e-36 123.3 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX96252.1 - 4.7e-13 49.5 0.2 5.8e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX96252.1 - 4.9e-05 22.8 0.3 0.0028 17.1 0.2 2.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX96252.1 - 0.0016 17.2 2.3 0.0058 15.3 0.5 2.4 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KFX96252.1 - 0.022 14.6 0.3 0.042 13.7 0.2 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KFX96252.1 - 0.025 14.2 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.12 KFX96252.1 - 0.039 14.3 0.3 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KFX96252.1 - 0.1 12.9 0.3 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.13 KFX96254.1 - 0.0099 15.7 13.1 0.0099 15.7 9.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.19 KFX96255.1 - 8.5e-25 87.2 0.0 1.3e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ADP_ribosyl_GH PF03747.9 KFX96256.1 - 2.1e-61 208.2 0.0 2.6e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_Omp PF13488.1 KFX96256.1 - 0.0016 18.0 3.2 0.36 10.5 0.6 2.6 2 0 0 2 2 2 2 Glycine zipper Gly-zipper_YMGG PF13441.1 KFX96256.1 - 0.0047 16.4 4.8 0.24 10.9 0.8 2.5 2 0 0 2 2 2 2 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 KFX96256.1 - 0.026 14.1 9.9 0.72 9.5 0.5 2.4 2 0 0 2 2 2 0 Glycine zipper 2TM domain Transgly_assoc PF04226.8 KFX96256.1 - 0.081 13.0 0.6 4 7.5 0.1 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein Gly-zipper_OmpA PF13436.1 KFX96256.1 - 0.29 10.8 2.0 3.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KFX96256.1 - 0.5 10.5 3.1 14 5.9 0.3 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Glyco_hydro_43 PF04616.9 KFX96257.1 - 1.5e-30 106.3 7.0 1.5e-30 106.3 4.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Ribosomal_L7Ae PF01248.21 KFX96258.1 - 1e-23 82.6 0.0 1.1e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynamin_N PF00350.18 KFX96259.1 - 3.2e-29 101.8 1.3 5.2e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFX96259.1 - 2.4e-21 75.7 0.2 3.7e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 KFX96259.1 - 0.0013 18.6 0.5 0.0036 17.1 0.3 1.8 1 1 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX96259.1 - 0.0015 18.4 0.0 0.0055 16.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX96259.1 - 0.011 16.1 0.1 0.037 14.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein NOA36 PF06524.7 KFX96259.1 - 0.052 12.7 6.2 0.085 12.1 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_29 PF13555.1 KFX96259.1 - 0.066 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain APH PF01636.18 KFX96260.1 - 1.1e-05 25.3 0.0 4.7e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFX96260.1 - 0.00015 20.5 0.0 0.0015 17.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Fungal_trans PF04082.13 KFX96262.1 - 8.1e-36 123.2 0.0 3.2e-35 121.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96262.1 - 8.5e-08 31.9 8.4 1.4e-07 31.2 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAV_VP3 PF04771.7 KFX96262.1 - 0.036 14.0 6.0 0.096 12.6 4.2 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Anoctamin PF04547.7 KFX96262.1 - 0.12 11.0 2.2 0.18 10.4 1.5 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Kinetochor_Ybp2 PF08568.5 KFX96263.1 - 2.1e-125 419.4 0.0 2.7e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin ILVD_EDD PF00920.16 KFX96264.1 - 3.4e-198 659.3 3.4 3.9e-198 659.0 2.4 1.0 1 0 0 1 1 1 1 Dehydratase family Bgal_small_N PF02929.12 KFX96265.1 - 6.1e-34 117.3 0.1 7.6e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Beta galactosidase small chain ADH_zinc_N PF00107.21 KFX96270.1 - 8.4e-14 51.2 0.1 1.7e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX96270.1 - 0.032 13.9 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MORN PF02493.15 KFX96270.1 - 3.7 7.4 6.1 8.9 6.2 0.1 3.0 3 0 0 3 3 3 0 MORN repeat CBFD_NFYB_HMF PF00808.18 KFX96271.1 - 4.1e-17 61.9 0.6 7.2e-17 61.2 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX96271.1 - 1.3e-05 25.2 0.1 8.9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF1284 PF06935.6 KFX96272.1 - 0.054 13.6 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) zf-MYND PF01753.13 KFX96272.1 - 0.36 10.7 3.7 0.53 10.2 2.6 1.2 1 0 0 1 1 1 0 MYND finger adh_short PF00106.20 KFX96273.1 - 7.1e-26 91.1 1.7 1e-25 90.6 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX96273.1 - 7.5e-17 61.9 0.0 1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX96273.1 - 4.1e-10 39.6 1.3 6.6e-10 38.9 0.9 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX96273.1 - 2.2e-06 27.8 0.4 4.6e-06 26.7 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX96273.1 - 0.0014 17.5 0.2 0.0029 16.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein PP2C_2 PF13672.1 KFX96273.1 - 0.002 17.5 0.2 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Epimerase PF01370.16 KFX96273.1 - 0.0058 16.0 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KFX96273.1 - 0.0099 15.8 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain DUF1776 PF08643.5 KFX96273.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KFX96273.1 - 0.068 12.4 0.1 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KFX96273.1 - 0.1 12.3 0.3 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 KFX96273.1 - 0.13 11.2 0.1 3.5 6.4 0.0 2.3 2 1 1 3 3 3 0 Male sterility protein dCMP_cyt_deam_1 PF00383.17 KFX96275.1 - 1.3e-22 79.3 0.0 2e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KFX96275.1 - 9.9e-06 25.4 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase NADH_u_ox_C PF12853.2 KFX96276.1 - 5.7e-35 118.9 0.2 8.5e-35 118.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 KFX96276.1 - 1.3e-33 115.0 0.3 2e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Nup54 PF13874.1 KFX96277.1 - 4.2e-43 146.3 0.0 4.2e-43 146.3 0.0 2.8 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KFX96277.1 - 1.9e-18 66.7 78.0 2e-10 40.9 28.2 2.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region Med26 PF08711.6 KFX96278.1 - 1.8e-11 43.3 0.0 3.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Phosphodiest PF01663.17 KFX96279.1 - 4.2e-86 289.5 0.1 5.5e-86 289.1 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX96279.1 - 0.0021 17.3 0.2 0.089 11.9 0.1 2.5 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 KFX96279.1 - 0.027 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 PglZ domain Dsh_C PF12316.3 KFX96279.1 - 2.7 8.0 10.7 0.19 11.8 3.3 2.0 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal PAM2 PF07145.10 KFX96280.1 - 5.7 6.6 25.9 0.27 10.8 0.7 5.5 6 0 0 6 6 6 0 Ataxin-2 C-terminal region Glyco_hydro_17 PF00332.13 KFX96281.1 - 3.3e-28 98.6 1.2 4.9e-26 91.4 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PQ-loop PF04193.9 KFX96282.1 - 1.7e-37 126.7 14.1 4.1e-21 74.2 0.0 3.3 3 1 1 4 4 4 2 PQ loop repeat GRIP PF01465.15 KFX96298.1 - 6.2e-06 25.6 0.0 6.5e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 GRIP domain HEAT_EZ PF13513.1 KFX96298.1 - 0.029 14.8 0.0 0.032 14.7 0.0 1.0 1 0 0 1 1 1 0 HEAT-like repeat MFS_2 PF13347.1 KFX96301.1 - 4.7e-12 45.0 13.6 1.4e-11 43.4 9.4 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 KFX96301.1 - 0.068 12.9 6.8 0.31 10.8 0.0 3.5 3 1 0 3 3 3 0 MFS_1 like family BioY PF02632.9 KFX96304.1 - 0.32 10.6 11.8 0.085 12.4 5.5 2.0 1 1 1 2 2 2 0 BioY family Na_H_Exchanger PF00999.16 KFX96304.1 - 1.9 6.9 14.0 0.14 10.6 2.4 2.9 1 1 2 3 3 3 0 Sodium/hydrogen exchanger family Peptidase_M1 PF01433.15 KFX96305.1 - 7.7e-138 459.8 0.3 1.1e-137 459.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFX96305.1 - 1.1e-92 310.7 0.1 2.6e-92 309.5 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFX96305.1 - 3e-19 69.3 0.1 6.1e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily WD40 PF00400.27 KFX96306.1 - 5.8e-09 35.5 0.5 4.5e-07 29.4 0.2 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat BicD PF09730.4 KFX96306.1 - 0.14 10.4 15.0 0.21 9.8 10.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D TBPIP PF07106.8 KFX96306.1 - 0.98 8.9 17.9 1.8 8.1 12.4 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUSC PF04632.7 KFX96306.1 - 1.4 7.2 3.8 2.1 6.6 2.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_p24 PF05073.7 KFX96306.1 - 3.6 7.1 8.6 7.1 6.1 5.9 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Hid1 PF12722.2 KFX96306.1 - 7.3 4.1 10.2 9.9 3.6 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Fip1 PF05182.8 KFX96308.1 - 3e-20 71.1 1.0 3e-20 71.1 0.7 1.7 2 0 0 2 2 2 1 Fip1 motif Myc_N PF01056.13 KFX96308.1 - 0.014 14.5 6.4 0.026 13.6 4.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.1 KFX96308.1 - 4.8 6.8 5.2 9.3 5.9 3.6 1.5 1 0 0 1 1 1 0 FAM176 family Nucleoporin_FG PF13634.1 KFX96309.1 - 1.5e-18 67.0 93.3 5.9e-12 45.8 29.5 2.7 1 1 1 2 2 2 2 Nucleoporin FG repeat region WD40 PF00400.27 KFX96310.1 - 3.3e-05 23.6 15.1 0.016 15.0 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat PQ-loop PF04193.9 KFX96311.1 - 1.1e-21 76.1 19.4 1.3e-11 43.9 1.3 3.5 3 1 1 4 4 4 2 PQ loop repeat Adipogenin PF15202.1 KFX96311.1 - 0.2 11.5 3.5 5.4 6.9 0.2 2.7 2 0 0 2 2 2 0 Adipogenin GST_N_3 PF13417.1 KFX96313.1 - 2.8e-14 53.0 0.0 4.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX96313.1 - 3.2e-13 49.6 0.1 8.2e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX96313.1 - 2e-11 43.7 0.0 3.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX96313.1 - 5.3e-11 42.3 0.0 8.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX96313.1 - 6.5e-07 29.1 0.1 9.2e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX96313.1 - 6.1e-06 26.6 0.3 8.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KFX96313.1 - 0.0058 17.0 0.0 0.0096 16.3 0.0 1.3 1 0 0 1 1 1 1 MetRS-N binding domain GMC_oxred_N PF00732.14 KFX96314.1 - 1.9e-56 191.3 0.0 2.7e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX96314.1 - 2.8e-35 121.7 0.1 6.2e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX96314.1 - 1.3e-09 37.4 0.5 4.6e-08 32.3 0.4 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX96314.1 - 2.1e-06 26.8 0.1 2.1e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX96314.1 - 0.00015 21.9 0.1 0.054 13.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX96314.1 - 0.00028 20.8 0.0 0.00075 19.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX96314.1 - 0.00079 19.4 0.2 0.0028 17.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX96314.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX96314.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FTA2 PF13095.1 KFX96315.1 - 0.098 12.2 0.1 2.3 7.7 0.0 2.4 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 KFX96315.1 - 0.14 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain Peptidase_M3 PF01432.15 KFX96316.1 - 2e-121 406.2 0.0 7.4e-121 404.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M3 adh_short PF00106.20 KFX96316.1 - 8.5e-24 84.3 0.1 1.7e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX96316.1 - 1.9e-20 73.6 0.0 3.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX96316.1 - 2.9e-06 27.0 0.0 8.6e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 KFX96316.1 - 7.5e-05 22.0 0.0 0.17 10.9 0.0 2.7 3 0 0 3 3 3 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFX96316.1 - 0.00023 21.2 0.2 0.00045 20.2 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KFX96316.1 - 0.00058 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KFX96316.1 - 0.0091 15.2 0.2 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KFX96316.1 - 0.058 13.3 0.2 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KFX96316.1 - 0.064 12.4 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFX96316.1 - 0.096 12.3 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M91 PF14891.1 KFX96316.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Effector protein Fungal_trans PF04082.13 KFX96317.1 - 1.9e-06 26.9 1.8 2.2e-05 23.4 1.2 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96317.1 - 9.3e-05 22.2 7.2 0.00015 21.5 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX96318.1 - 2.6e-102 342.7 19.6 3.2e-102 342.4 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96318.1 - 2.9e-23 82.1 34.9 8.4e-22 77.3 16.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX96318.1 - 7.4e-07 27.9 17.7 0.00068 18.1 1.4 3.4 3 0 0 3 3 3 3 MFS/sugar transport protein TauD PF02668.11 KFX96319.1 - 2.6e-48 164.9 0.1 3.1e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_N PF08240.7 KFX96320.1 - 1.4e-26 92.4 6.7 3.1e-26 91.2 4.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX96320.1 - 8.9e-19 67.3 1.4 1.3e-18 66.7 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX96320.1 - 0.0003 21.6 0.2 0.00048 21.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldedh PF00171.17 KFX96321.1 - 1.8e-134 448.6 0.1 2.1e-134 448.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX96321.1 - 0.0012 17.6 0.0 0.0034 16.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aa_trans PF01490.13 KFX96322.1 - 9.6e-81 271.3 24.7 1.1e-80 271.0 17.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 KFX96323.1 - 6.6e-13 48.0 17.9 6.6e-13 48.0 12.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3754 PF12576.3 KFX96323.1 - 0.14 11.7 0.4 0.4 10.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) DDE_Tnp_IS1 PF03400.8 KFX96324.1 - 0.031 14.3 0.1 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 IS1 transposase DUF3834 PF12916.2 KFX96324.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Sugar_tr PF00083.19 KFX96325.1 - 1.2e-66 225.1 22.7 1.5e-66 224.8 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96325.1 - 2.3e-16 59.4 28.2 1.6e-13 50.0 18.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF1680 PF07944.7 KFX96326.1 - 4.8e-120 401.2 0.0 5.8e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) DUF3455 PF11937.3 KFX96327.1 - 7.6e-45 153.0 0.1 9.2e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Cation_efflux PF01545.16 KFX96329.1 - 3.8e-31 108.2 5.2 4.7e-31 107.9 3.6 1.1 1 0 0 1 1 1 1 Cation efflux family DctQ PF04290.7 KFX96329.1 - 0.2 11.4 3.0 0.33 10.6 0.1 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-rbx1 PF12678.2 KFX96330.1 - 4e-11 42.8 0.2 8.1e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFX96330.1 - 1.4e-10 40.8 5.5 4.1e-10 39.3 1.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX96330.1 - 1.7e-07 30.7 3.8 3.7e-06 26.5 0.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX96330.1 - 6.9e-06 25.6 0.6 2.4e-05 23.9 0.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX96330.1 - 1e-05 25.1 1.4 5.8e-05 22.7 0.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX96330.1 - 4e-05 23.5 1.8 4e-05 23.5 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX96330.1 - 0.0097 15.6 1.6 0.0097 15.6 1.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 KFX96330.1 - 0.01 15.6 1.7 0.052 13.3 0.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFX96330.1 - 0.057 13.3 1.2 0.13 12.1 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFX96330.1 - 0.55 9.8 3.7 0.19 11.3 0.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.15 KFX96331.1 - 9.2e-34 116.8 0.1 1.4e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KFX96331.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative VCBS PF13517.1 KFX96332.1 - 4.5e-35 119.8 59.9 2.9e-09 37.1 2.0 8.8 5 2 5 10 10 10 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFX96332.1 - 9.9e-14 50.5 39.9 0.0001 21.8 0.7 7.3 6 0 0 6 6 6 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 KFX96332.1 - 1.5e-09 37.5 9.1 0.15 11.4 0.0 6.0 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.17 KFX96332.1 - 1.9e-09 37.7 0.1 3.9e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX96332.1 - 6.9e-08 32.8 0.1 1.5e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DNA_processg_A PF02481.10 KFX96360.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A HMG_box PF00505.14 KFX96361.1 - 1.4e-11 44.4 0.1 1.4e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX96361.1 - 0.001 19.3 0.1 0.001 19.3 0.1 2.0 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 KFX96361.1 - 0.062 12.6 0.0 0.062 12.6 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 Sld5 PF05916.6 KFX96362.1 - 1.1e-12 48.1 0.1 2e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 KFX96362.1 - 0.019 14.5 0.0 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) DUF2365 PF10157.4 KFX96362.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Sulfate_transp PF00916.15 KFX96363.1 - 2.4e-41 141.5 0.8 6.1e-41 140.2 0.5 1.7 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KFX96363.1 - 2.8e-17 62.3 0.0 6.6e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KFX96363.1 - 2.3e-09 36.6 0.0 4.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain Glyco_hydro_10 PF00331.15 KFX96364.1 - 4.2e-91 305.3 5.6 5.2e-91 304.9 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 adh_short PF00106.20 KFX96365.1 - 4.8e-23 81.8 0.1 6.5e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX96365.1 - 6.5e-11 42.2 0.1 1.3e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 KR domain Ras PF00071.17 KFX96366.1 - 2.3e-40 137.6 0.0 3.5e-40 137.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFX96366.1 - 1.3e-14 54.7 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX96366.1 - 2.3e-10 40.0 0.0 3.2e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX96366.1 - 0.00024 20.3 0.0 0.00032 19.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX96366.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX96366.1 - 0.014 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFX96366.1 - 0.014 14.8 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KFX96366.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KFX96366.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KFX96366.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFX96366.1 - 0.021 14.3 0.1 0.088 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX96366.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX96366.1 - 0.024 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX96366.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.5 2 0 0 2 2 1 0 NACHT domain DUF258 PF03193.11 KFX96366.1 - 0.035 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KFX96366.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFX96366.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFX96366.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 KFX96366.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Sugar_tr PF00083.19 KFX96367.1 - 7.5e-99 331.3 16.4 8.7e-99 331.1 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96367.1 - 5.5e-22 77.9 28.5 3.8e-21 75.2 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX96367.1 - 1.1e-05 23.9 22.0 0.013 13.8 4.0 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 KFX96367.1 - 4.1e-05 21.9 9.2 0.0059 14.8 1.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KFX96367.1 - 1.5 8.9 7.8 0.11 12.5 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Sulfatase PF00884.18 KFX96368.1 - 2.1e-72 243.9 0.0 2.5e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFX96368.1 - 0.1 11.8 0.1 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Zn_clus PF00172.13 KFX96369.1 - 2.9e-07 30.2 6.1 5.9e-07 29.3 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX96369.1 - 2.5e-05 23.2 0.0 6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSF_DNA-bind PF00447.12 KFX96369.1 - 0.015 15.4 0.4 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding Peptidase_A4 PF01828.12 KFX96370.1 - 4.2e-47 159.8 9.3 5.2e-47 159.5 6.5 1.1 1 0 0 1 1 1 1 Peptidase A4 family Ecm33 PF12454.3 KFX96370.1 - 0.0014 18.4 1.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 2 GPI-anchored cell wall organization protein Poly_export PF02563.11 KFX96370.1 - 0.0019 17.9 0.1 0.46 10.2 0.1 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis/export protein Dynamin_N PF00350.18 KFX96372.1 - 2.3e-28 99.0 0.0 6.8e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFX96372.1 - 1.1e-12 47.3 0.1 4.3e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 KFX96372.1 - 0.0002 21.1 0.0 0.00066 19.5 0.0 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX96372.1 - 0.002 18.0 0.0 0.047 13.6 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFX96372.1 - 0.0048 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein EHN PF06441.7 KFX96373.1 - 4.1e-19 68.5 0.2 5.3e-17 61.7 0.1 2.3 1 1 1 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFX96373.1 - 4.3e-13 49.6 0.1 1.7e-12 47.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX96373.1 - 3.9e-11 42.9 0.0 8.6e-11 41.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.2 KFX96374.1 - 0.0013 18.3 0.2 0.0036 17.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like RskA PF10099.4 KFX96382.1 - 0.31 10.7 7.8 0.31 10.7 5.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1793 PF08760.6 KFX96384.1 - 1.5e-72 243.0 0.1 3.1e-72 241.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Cellulase PF00150.13 KFX96386.1 - 2.4e-08 33.5 0.1 2.4e-08 33.5 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Carb_bind PF10645.4 KFX96386.1 - 0.051 13.3 1.0 1.2 8.9 0.4 2.7 3 0 0 3 3 3 0 Carbohydrate binding DUF1510 PF07423.6 KFX96386.1 - 0.071 12.4 0.0 0.071 12.4 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) DUF515 PF04415.7 KFX96386.1 - 0.19 9.9 0.3 0.32 9.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) OAD_gamma PF04277.8 KFX96386.1 - 1.3 9.4 3.3 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Transket_pyr PF02779.19 KFX96387.1 - 2.8e-42 144.2 0.0 4.2e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFX96387.1 - 6.5e-32 110.0 0.0 1.4e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Oxidored_FMN PF00724.15 KFX96388.1 - 2.3e-56 191.2 0.0 2.8e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 KFX96388.1 - 0.0016 17.3 1.3 0.13 11.0 0.3 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Dus PF01207.12 KFX96388.1 - 0.15 10.8 0.4 1.8 7.3 0.0 2.4 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) GRAM PF02893.15 KFX96396.1 - 6.3e-18 64.0 0.0 1.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Peptidase_S8 PF00082.17 KFX96413.1 - 1.5e-55 188.3 3.7 2e-55 187.9 2.5 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KFX96413.1 - 2.6e-25 88.0 0.4 5.6e-25 86.9 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain eIF3_subunit PF08597.5 KFX96415.1 - 5.4e-45 153.8 5.0 6e-45 153.7 3.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit APC_CDC26 PF10471.4 KFX96419.1 - 1e-11 45.4 2.9 1.3e-11 45.0 2.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Urm1 PF09138.6 KFX96436.1 - 5.8e-22 77.6 0.1 3.1e-16 59.2 0.0 2.0 1 1 1 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KFX96436.1 - 0.0094 16.3 0.0 0.011 16.1 0.0 1.3 1 1 0 1 1 1 1 ThiS family zf-C2H2 PF00096.21 KFX96437.1 - 1.5e-13 50.2 17.4 5.8e-05 23.1 1.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX96437.1 - 2e-10 40.4 20.8 3.4e-09 36.5 0.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX96437.1 - 5.7e-09 35.6 15.4 0.0039 17.4 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger GAGA PF09237.6 KFX96437.1 - 0.038 13.5 1.2 4.8 6.8 0.1 2.6 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.2 KFX96437.1 - 0.062 13.5 0.5 6.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KFX96437.1 - 0.075 12.7 3.6 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Fer2 PF00111.22 KFX96437.1 - 0.094 12.4 0.3 0.27 10.9 0.2 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Zn-ribbon_8 PF09723.5 KFX96437.1 - 3.8 7.5 7.5 7.5 6.6 1.7 3.0 2 1 0 2 2 2 0 Zinc ribbon domain GTP_EFTU PF00009.22 KFX96453.1 - 9e-56 188.2 0.2 1.4e-55 187.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFX96453.1 - 3.9e-33 113.1 0.0 7.9e-33 112.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KFX96453.1 - 1.1e-31 108.8 0.1 2.3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFX96453.1 - 2.6e-24 84.8 0.0 4.8e-23 80.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX96453.1 - 4.9e-13 48.9 0.0 1.1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 KFX96453.1 - 0.12 12.2 0.1 17 5.3 0.0 3.4 4 0 0 4 4 4 0 Putative phosphatase (DUF442) DUF4235 PF14019.1 KFX96454.1 - 0.15 11.9 1.2 0.86 9.4 0.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) Abhydrolase_6 PF12697.2 KFX96455.1 - 4.7e-10 39.7 3.1 9e-10 38.8 1.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX96455.1 - 3.7e-05 23.5 0.0 7.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX96455.1 - 0.00037 20.1 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFX96455.1 - 0.015 14.9 0.2 0.028 13.9 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1282 PF06930.7 KFX96455.1 - 0.052 13.2 2.1 0.063 12.9 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Abhydrolase_8 PF06259.7 KFX96455.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Aldo_ket_red PF00248.16 KFX96456.1 - 7.4e-57 192.3 0.0 1.5e-56 191.3 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family Fructosamin_kin PF03881.9 KFX96456.1 - 2.5e-42 144.8 0.1 3.6e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Fructosamine kinase WD40 PF00400.27 KFX96457.1 - 7e-06 25.7 0.0 7.8 6.5 0.0 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 KFX96457.1 - 7.8e-06 24.4 0.0 0.077 11.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) NACHT PF05729.7 KFX96457.1 - 5.7e-05 22.8 0.1 0.00024 20.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Abhydrolase_6 PF12697.2 KFX96457.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX96457.1 - 0.00028 20.2 0.0 0.00076 18.8 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PQQ_2 PF13360.1 KFX96457.1 - 0.0029 17.1 0.0 0.29 10.5 0.0 2.9 1 1 0 1 1 1 1 PQQ-like domain Abhydrolase_5 PF12695.2 KFX96457.1 - 0.0087 15.8 0.0 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFX96457.1 - 0.014 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein VID27 PF08553.5 KFX96457.1 - 0.055 11.7 0.5 1.6 6.8 0.0 2.4 3 0 0 3 3 3 0 VID27 cytoplasmic protein AAA_22 PF13401.1 KFX96457.1 - 0.11 12.6 0.2 1.1 9.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain DAO PF01266.19 KFX96458.1 - 4.1e-35 121.3 1.2 5.4e-35 120.9 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX96458.1 - 0.0089 16.0 0.3 0.026 14.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX96458.1 - 0.011 15.5 0.1 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_transf_54 PF04666.8 KFX96459.1 - 1.9e-09 36.6 0.0 0.0015 17.2 0.1 3.0 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region EF-hand_1 PF00036.27 KFX96459.1 - 1.2e-05 24.2 1.4 1.6e-05 23.8 0.2 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KFX96459.1 - 1.5e-05 24.4 0.5 4.2e-05 23.0 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KFX96459.1 - 0.00067 19.7 0.2 0.0042 17.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KFX96459.1 - 0.00074 18.7 0.6 0.0014 17.8 0.4 1.5 1 0 0 1 1 1 1 EF hand Glyco_transf_25 PF01755.12 KFX96459.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) ADH_zinc_N_2 PF13602.1 KFX96460.1 - 1.1e-26 94.1 0.5 2.5e-26 93.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX96460.1 - 8.6e-18 64.1 0.2 2.5e-17 62.6 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX96460.1 - 2.9e-06 26.9 0.0 8.8e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_2 PF07992.9 KFX96461.1 - 1.5e-21 77.2 3.7 1.4e-10 41.3 0.0 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX96461.1 - 2.7e-20 72.5 0.5 2.7e-20 72.5 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFX96461.1 - 8.4e-20 70.8 0.0 1.8e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 KFX96461.1 - 4.5e-08 33.3 0.4 0.00015 21.9 0.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX96461.1 - 7.4e-08 31.6 13.2 8.6e-05 21.5 0.1 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase GIDA PF01134.17 KFX96461.1 - 7.4e-08 31.6 11.8 0.0015 17.4 0.5 3.8 2 1 2 4 4 4 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KFX96461.1 - 5.6e-07 28.8 7.2 0.041 12.7 0.1 3.2 3 0 0 3 3 3 3 Lycopene cyclase protein HI0933_like PF03486.9 KFX96461.1 - 1.5e-05 23.6 11.5 0.0042 15.6 0.4 3.2 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.13 KFX96461.1 - 0.0001 21.9 4.9 0.0069 16.0 0.2 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX96461.1 - 0.00041 19.3 7.0 0.013 14.3 0.5 2.7 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 KFX96461.1 - 0.00074 19.7 0.8 0.0052 17.0 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX96461.1 - 0.0028 16.8 0.0 0.019 14.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KFX96461.1 - 0.022 13.8 2.5 0.38 9.8 0.0 2.6 3 0 0 3 3 3 0 Thi4 family NAD_binding_8 PF13450.1 KFX96461.1 - 0.025 14.6 5.3 2.5 8.1 0.3 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KFX96461.1 - 0.034 13.2 0.1 0.066 12.2 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFX96461.1 - 0.065 12.6 3.1 0.59 9.4 0.2 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KFX96461.1 - 0.24 11.2 2.2 0.42 10.4 0.1 2.3 2 0 0 2 2 2 0 ThiF family zf-C2H2_4 PF13894.1 KFX96462.1 - 6.5e-12 44.8 27.2 0.0012 19.0 1.5 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX96462.1 - 1.3e-10 40.9 28.4 0.0061 16.8 2.5 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX96462.1 - 0.00054 20.1 30.5 0.064 13.5 0.8 4.9 5 0 0 5 5 5 3 Zinc-finger double domain DUF629 PF04780.7 KFX96462.1 - 3.7 5.9 12.5 0.36 9.2 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) DUF2527 PF10736.4 KFX96462.1 - 4.5 6.9 8.4 13 5.4 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) SKG6 PF08693.5 KFX96463.1 - 0.00028 20.1 0.0 0.0005 19.3 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CAP59_mtransfer PF11735.3 KFX96466.1 - 6.6e-65 218.7 0.0 8.9e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ATP-synt_ab PF00006.20 KFX96467.1 - 1.1e-61 208.0 0.0 1.7e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFX96467.1 - 3.7e-25 88.6 0.6 6.5e-25 87.8 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFX96467.1 - 7.7e-24 83.6 0.4 2e-23 82.3 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KFX96467.1 - 0.0009 18.6 0.1 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFX96467.1 - 0.009 15.7 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 KFX96467.1 - 0.0098 16.0 0.1 0.54 10.4 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFX96467.1 - 0.014 14.5 0.1 0.023 13.8 0.1 1.4 1 0 0 1 1 1 0 KaiC MobB PF03205.9 KFX96467.1 - 0.015 15.0 0.2 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KFX96467.1 - 0.015 14.4 0.2 0.028 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KFX96467.1 - 0.031 13.9 0.2 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KFX96467.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KFX96467.1 - 0.077 12.9 0.2 0.39 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain EKR PF10371.4 KFX96467.1 - 0.092 12.3 0.0 0.33 10.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function NB-ARC PF00931.17 KFX96467.1 - 0.26 10.0 0.8 0.76 8.5 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 KFX96468.1 - 2e-24 85.5 0.1 5.6e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 KFX96468.1 - 1.3e-19 69.9 0.1 3.9e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 KFX96468.1 - 2.3e-18 66.6 0.2 1.9e-14 53.8 0.1 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Rho_Binding PF08912.6 KFX96468.1 - 0.043 14.1 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Rho Binding AAA_2 PF07724.9 KFX96469.1 - 2.8e-37 128.2 0.0 8.4e-37 126.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFX96469.1 - 4.4e-12 46.3 0.0 7.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KFX96469.1 - 4e-08 33.0 0.0 9.6e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KFX96469.1 - 5.4e-06 26.1 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFX96469.1 - 1.6e-05 25.6 0.1 4.9e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KFX96469.1 - 0.00011 22.3 0.1 0.0016 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFX96469.1 - 0.0015 17.9 0.8 0.0024 17.3 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KFX96469.1 - 0.0029 17.6 0.0 0.0089 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KFX96469.1 - 0.0036 16.7 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFX96469.1 - 0.0037 17.1 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 KFX96469.1 - 0.015 14.1 0.2 0.015 14.1 0.1 2.1 2 1 0 2 2 2 0 MCM2/3/5 family AAA_18 PF13238.1 KFX96469.1 - 0.02 15.2 0.2 0.085 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFX96469.1 - 0.027 13.9 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFX96469.1 - 0.043 13.4 1.3 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KFX96469.1 - 0.045 12.9 0.1 4.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.2 KFX96469.1 - 0.053 13.0 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_24 PF13479.1 KFX96469.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFX96469.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KFX96469.1 - 0.077 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFX96469.1 - 0.082 11.9 0.2 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 KFX96469.1 - 0.086 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 KFX96469.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFX96469.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase COX4 PF02936.9 KFX96470.1 - 1.9e-49 167.0 0.0 2.8e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 KFX96470.1 - 0.18 11.9 0.1 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Gp_dh_C PF02800.15 KFX96471.1 - 9.4e-73 242.8 0.9 1.5e-72 242.1 0.6 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFX96471.1 - 4.5e-59 198.7 0.7 7.4e-59 198.0 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX96471.1 - 0.067 13.1 0.4 0.53 10.2 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KFX96471.1 - 0.078 12.1 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Molybdopterin PF00384.17 KFX96472.1 - 1.5e-74 251.3 0.0 9e-73 245.4 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KFX96472.1 - 2.9e-19 68.0 0.1 7.5e-19 66.6 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KFX96472.1 - 1.6e-18 66.2 0.1 4.8e-18 64.7 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 KFX96472.1 - 8.3e-15 54.6 0.0 2e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KFX96472.1 - 1.2e-07 31.3 0.4 1.2e-07 31.3 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KFX96472.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PAT1 PF09770.4 KFX96474.1 - 0.018 13.3 5.7 0.024 12.9 4.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PSRP-3_Ycf65 PF04839.8 KFX96474.1 - 1.2 9.2 3.2 1.9 8.5 2.2 1.2 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) MHYT PF03707.11 KFX96490.1 - 2.3e-14 53.2 22.3 4e-07 30.0 1.0 5.1 5 0 0 5 5 5 3 Bacterial signalling protein N terminal repeat DUF3377 PF11857.3 KFX96490.1 - 0.73 9.4 3.0 0.54 9.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF1772 PF08592.6 KFX96490.1 - 0.75 9.5 17.8 0.16 11.6 5.4 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Peptidase_A24 PF01478.13 KFX96490.1 - 3.6 7.8 9.0 14 5.8 2.0 2.7 2 0 0 2 2 2 0 Type IV leader peptidase family DUF4131 PF13567.1 KFX96490.1 - 4.5 6.6 15.0 0.66 9.3 4.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4407 PF14362.1 KFX96490.1 - 8.6 5.2 7.6 16 4.3 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1684 PF07920.6 KFX96491.1 - 0.011 15.6 0.1 5.3 6.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1684) Sugar_tr PF00083.19 KFX96492.1 - 1.7e-98 330.1 17.3 1.9e-98 329.9 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96492.1 - 4.9e-42 143.9 25.6 1.2e-34 119.5 10.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KFX96493.1 - 1e-10 41.3 6.0 1.8e-10 40.5 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_C PF02836.12 KFX96494.1 - 9.7e-104 346.4 0.0 1.3e-103 345.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KFX96494.1 - 9.3e-55 185.5 0.0 1.7e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KFX96494.1 - 5.4e-52 175.7 0.2 1e-51 174.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX96494.1 - 2.1e-18 66.7 0.2 6.2e-18 65.2 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFX96494.1 - 0.018 15.3 1.0 0.061 13.5 0.1 2.3 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain NmrA PF05368.8 KFX96495.1 - 9.7e-26 90.4 0.0 1.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX96495.1 - 1.6e-06 28.2 0.4 3e-06 27.3 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX96495.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GED PF02212.13 KFX96497.1 - 1.1e-32 111.7 2.5 1.6e-32 111.2 1.7 1.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain Epimerase PF01370.16 KFX96498.1 - 0.00077 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Desmo_N PF06771.6 KFX96498.1 - 0.12 12.2 0.0 2.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus FAD_binding_3 PF01494.14 KFX96500.1 - 9.9e-10 37.9 1.0 3.6e-09 36.1 0.7 1.9 1 1 0 1 1 1 1 FAD binding domain DUF2721 PF11026.3 KFX96501.1 - 0.03 13.9 0.4 0.06 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Macoilin PF09726.4 KFX96501.1 - 1.5 7.0 7.5 1.6 6.8 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S8e PF01201.17 KFX96502.1 - 2.7e-37 127.8 3.8 8.2e-36 123.0 2.7 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 KFX96502.1 - 3.5 6.8 7.7 1.1 8.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) LCD1 PF09798.4 KFX96502.1 - 8.6 4.2 9.0 11 3.8 6.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Y_phosphatase3 PF13350.1 KFX96503.1 - 2.5e-28 99.4 0.2 4.3e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFX96503.1 - 2.2e-07 30.8 0.3 4.6e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KFX96503.1 - 6.8e-06 25.5 0.0 2.2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 KFX96503.1 - 0.00092 18.7 0.1 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX96503.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 KFX96503.1 - 0.035 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain zf-H2C2_2 PF13465.1 KFX96506.1 - 6.6e-06 26.1 4.0 6.6e-06 26.1 2.8 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFX96506.1 - 1.7e-05 24.8 11.1 0.0074 16.5 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX96506.1 - 2.5e-05 24.2 12.8 0.0034 17.5 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger DUF713 PF05218.9 KFX96508.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Flavi_capsid PF01003.14 KFX96509.1 - 0.074 12.5 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus capsid protein C DUF3505 PF12013.3 KFX96510.1 - 0.0014 18.8 0.1 0.0045 17.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DSPc PF00782.15 KFX96526.1 - 4.9e-22 77.9 0.1 5e-20 71.4 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX96526.1 - 0.0017 17.7 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Choline_kinase PF01633.15 KFX96533.1 - 0.016 14.7 0.0 0.096 12.2 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Host_attach PF10116.4 KFX96533.1 - 0.03 14.5 3.6 2.2 8.5 0.7 2.3 2 0 0 2 2 2 0 Protein required for attachment to host cells CAML PF14963.1 KFX96533.1 - 0.044 13.1 3.0 0.087 12.1 2.1 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand APH PF01636.18 KFX96533.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cupin_1 PF00190.17 KFX96534.1 - 2.2e-12 46.5 0.4 3.4e-12 46.0 0.3 1.2 1 0 0 1 1 1 1 Cupin tify PF06200.9 KFX96534.1 - 0.0094 15.1 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 tify domain TauD PF02668.11 KFX96535.1 - 7e-43 147.1 0.0 8.7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fn3-like PF14310.1 KFX96535.1 - 0.12 12.3 0.3 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Fibronectin type III-like domain MFS_1 PF07690.11 KFX96536.1 - 2.8e-23 82.2 20.7 4e-23 81.7 14.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KFX96536.1 - 2e-15 56.3 0.0 5.3e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96536.1 - 3e-06 27.0 9.0 5.1e-06 26.2 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3712 PF12505.3 KFX96537.1 - 5.5e-40 136.2 2.9 1e-38 132.1 0.6 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) Cyt-b5 PF00173.23 KFX96537.1 - 0.00034 20.3 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2236 PF09995.4 KFX96538.1 - 2.5e-57 193.9 2.4 3.1e-57 193.6 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Fungal_trans PF04082.13 KFX96540.1 - 1.5e-05 23.9 1.5 2.5e-05 23.3 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 KFX96541.1 - 1.7e-75 254.0 0.0 2.2e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX96541.1 - 3.6e-15 56.6 0.2 8.1e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.19 KFX96542.1 - 2.7e-32 111.9 0.3 4.4e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX96542.1 - 3.4e-21 74.4 1.2 6.3e-21 73.6 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX96542.1 - 4.6e-16 59.4 0.0 1.4e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFX96542.1 - 2.4e-06 27.8 0.2 4e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FMO-like PF00743.14 KFX96543.1 - 4.4e-28 97.7 0.0 3e-11 42.2 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX96543.1 - 1.1e-20 74.5 0.1 2.6e-19 70.0 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX96543.1 - 4.6e-07 29.9 0.0 7.5e-05 22.6 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX96543.1 - 8e-07 28.9 0.3 0.0014 18.4 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFX96543.1 - 3e-06 26.3 1.4 0.0018 17.2 0.0 3.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX96543.1 - 5e-05 23.2 0.2 0.00023 21.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX96543.1 - 0.02 14.0 1.6 0.36 9.9 0.1 2.3 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KFX96543.1 - 0.039 14.0 0.5 0.41 10.7 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFX96543.1 - 0.063 13.7 0.9 9.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX96543.1 - 0.13 11.2 1.0 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KFX96543.1 - 0.15 10.4 1.9 0.14 10.5 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 KFX96544.1 - 1.1e-32 113.1 24.4 1.8e-32 112.4 16.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Inhibitor_I68 PF10468.4 KFX96545.1 - 0.2 11.8 0.5 0.2 11.8 0.3 1.8 2 1 0 2 2 2 0 Carboxypeptidase inhibitor I68 BATS PF06968.8 KFX96546.1 - 2.8e-26 91.1 0.0 8.2e-26 89.6 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KFX96546.1 - 2.1e-14 54.0 0.0 3.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily APH PF01636.18 KFX96547.1 - 1.5e-11 44.4 0.0 1.7e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX96547.1 - 1.6e-08 34.3 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFX96547.1 - 0.032 13.3 0.0 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 KFX96547.1 - 0.073 11.7 0.1 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WWamide PF08258.6 KFX96547.1 - 1.1 9.6 4.7 3.5 8.0 3.2 2.0 1 0 0 1 1 1 0 WWamide peptide HET PF06985.6 KFX96548.1 - 1.2e-26 93.5 0.1 2e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 KFX96549.1 - 3.9e-11 43.1 0.6 1.6e-09 37.8 0.4 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX96549.1 - 1.3e-05 24.8 0.0 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase MFS_1 PF07690.11 KFX96550.1 - 1.1e-44 152.6 40.7 1.8e-44 151.8 28.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX96550.1 - 1.2e-10 40.2 11.4 1.2e-10 40.2 7.9 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KFX96551.1 - 5.2e-19 68.1 0.0 1.4e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96551.1 - 6.6e-10 38.7 10.8 1.4e-09 37.7 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KFX96552.1 - 1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX96552.1 - 1.5e-08 35.0 0.0 3.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX96552.1 - 8.1e-07 28.7 0.0 5.5e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX96552.1 - 1.7e-06 28.4 0.0 1e-05 25.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX96552.1 - 1.9e-06 28.3 0.0 1.8e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX96552.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX96552.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX96552.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFX96552.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KFX96552.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFX96552.1 - 0.076 12.0 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 KFX96552.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 KFX96553.1 - 7.4e-58 196.1 0.0 1e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 KFX96554.1 - 3.7e-31 108.2 0.0 5.4e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III PPO1_DWL PF12142.3 KFX96554.1 - 0.097 12.2 0.1 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Polyphenol oxidase middle domain CLP_protease PF00574.18 KFX96556.1 - 4.8e-70 234.9 0.0 7.8e-70 234.2 0.0 1.3 1 1 0 1 1 1 1 Clp protease AbbA_antirepres PF14156.1 KFX96557.1 - 0.054 13.1 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Antirepressor AbbA TPR_11 PF13414.1 KFX96558.1 - 9.2e-06 25.2 1.1 1.7 8.3 0.0 4.6 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.1 KFX96558.1 - 8.4e-05 22.4 0.5 2.5 8.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX96558.1 - 0.00017 21.4 1.2 0.96 9.4 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96558.1 - 0.024 15.2 16.7 0.43 11.3 0.0 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat Nro1 PF12753.2 KFX96558.1 - 0.052 12.4 0.2 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 TPR_7 PF13176.1 KFX96558.1 - 0.094 12.5 2.8 79 3.4 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX96558.1 - 0.81 9.7 6.6 41 4.4 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFX96558.1 - 0.88 10.1 0.1 0.88 10.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.23 KFX96559.1 - 1.1e-16 60.6 0.0 1.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.20 KFX96560.1 - 6e-12 45.2 0.0 2.1e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX96560.1 - 3.2e-08 33.5 0.0 2.6e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFX96560.1 - 3.9e-07 29.3 0.0 8.1e-07 28.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFX96560.1 - 8.4e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFX96560.1 - 2.7e-06 26.6 0.0 3.6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFX96560.1 - 0.00075 18.4 0.0 0.00091 18.1 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KFX96560.1 - 0.001 18.0 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KFX96560.1 - 0.0015 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KFX96560.1 - 0.061 12.6 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_28 PF00295.12 KFX96561.1 - 4.8e-53 180.2 9.2 7.9e-53 179.5 6.4 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4066 PF13278.1 KFX96562.1 - 1.6e-30 105.5 0.0 2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX96562.1 - 2.6e-08 33.4 0.0 3.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_11 PF00457.12 KFX96563.1 - 2.5e-77 258.3 24.7 3e-77 258.1 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Cytochrom_B561 PF03188.11 KFX96564.1 - 0.00015 21.5 5.3 0.00032 20.5 3.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF998 PF06197.8 KFX96564.1 - 0.12 11.7 15.3 0.0094 15.2 3.8 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF998) Plant_vir_prot PF01307.12 KFX96564.1 - 0.12 12.1 2.0 0.2 11.4 0.4 2.1 2 0 0 2 2 2 0 Plant viral movement protein DUF4079 PF13301.1 KFX96564.1 - 0.42 10.5 8.5 0.16 11.9 1.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Ferric_reduct PF01794.14 KFX96564.1 - 0.51 10.4 9.0 0.13 12.4 0.7 2.6 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF2427 PF10348.4 KFX96564.1 - 0.69 9.5 3.5 2.2 7.9 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) NACHT PF05729.7 KFX96574.1 - 1.7e-10 40.8 0.2 6.4e-10 38.9 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFX96574.1 - 1.8e-09 37.8 0.2 5.4e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFX96574.1 - 1.4e-08 34.6 0.0 3.6e-07 30.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain Ank_2 PF12796.2 KFX96574.1 - 2.3e-05 24.6 0.0 0.0002 21.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX96574.1 - 0.00016 21.2 0.0 0.012 15.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat NB-ARC PF00931.17 KFX96574.1 - 0.00029 19.7 0.0 0.00067 18.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KFX96574.1 - 0.00056 20.0 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.1 KFX96574.1 - 0.0039 17.4 0.1 0.089 13.0 0.0 3.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Arch_ATPase PF01637.13 KFX96574.1 - 0.0062 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase DAP3 PF10236.4 KFX96574.1 - 0.01 14.7 0.1 0.025 13.5 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ank_3 PF13606.1 KFX96574.1 - 0.024 14.8 0.0 1.8 9.0 0.0 3.6 2 0 0 2 2 2 0 Ankyrin repeat AAA_25 PF13481.1 KFX96574.1 - 0.043 13.2 0.1 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ank_4 PF13637.1 KFX96574.1 - 0.058 13.9 0.0 1.3 9.6 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_29 PF13555.1 KFX96574.1 - 0.062 12.8 0.8 0.16 11.5 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KFX96574.1 - 0.12 11.5 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KFX96574.1 - 0.12 11.8 0.1 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX96574.1 - 0.14 12.9 0.0 0.69 10.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain Cupin_2 PF07883.6 KFX96576.1 - 0.00095 18.6 0.0 0.0034 16.8 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Rep_fac-A_3 PF08661.6 KFX96577.1 - 1.6e-23 82.6 0.0 1.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 FAM194 PF14977.1 KFX96577.1 - 0.039 12.9 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 FAM194 protein DUF2470 PF10615.4 KFX96577.1 - 0.15 12.3 0.3 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) tRNA-synt_2 PF00152.15 KFX96578.1 - 1.1e-89 300.6 0.5 1.7e-89 299.9 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFX96578.1 - 1.4e-09 37.7 0.0 3.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFX96578.1 - 9.5e-07 28.2 0.2 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.3 KFX96578.1 - 2.3 6.8 10.4 3.5 6.2 7.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CALCOCO1 PF07888.6 KFX96584.1 - 0.0017 16.7 15.0 0.0029 15.9 10.4 1.4 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FlxA PF14282.1 KFX96584.1 - 1 9.3 4.4 0.59 10.1 0.9 2.2 2 0 0 2 2 2 0 FlxA-like protein DivIVA PF05103.8 KFX96584.1 - 7 6.7 19.9 2.2 8.3 5.7 3.2 2 1 0 3 3 3 0 DivIVA protein DUF972 PF06156.8 KFX96584.1 - 8.4 6.7 16.3 26 5.2 1.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Pyr_redox_2 PF07992.9 KFX96585.1 - 4e-29 101.9 0.0 9.2e-29 100.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX96585.1 - 4.9e-16 58.8 1.7 2.3e-14 53.5 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KFX96585.1 - 2.1e-12 46.4 0.1 7.7e-12 44.6 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KFX96585.1 - 1.9e-11 44.4 0.1 0.00017 21.6 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KFX96585.1 - 1.9e-05 24.8 0.0 5.1e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 KFX96585.1 - 0.00011 21.3 0.1 0.25 10.2 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.1 KFX96585.1 - 0.0012 18.5 0.0 0.0074 16.0 0.0 2.3 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.1 KFX96585.1 - 0.0021 17.8 0.4 2.6 7.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KFX96585.1 - 0.0023 16.8 6.4 0.15 10.9 0.0 3.9 4 1 0 5 5 5 1 FAD dependent oxidoreductase DUF1188 PF06690.6 KFX96585.1 - 0.0048 16.0 0.1 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) HI0933_like PF03486.9 KFX96585.1 - 0.0062 15.0 1.4 0.18 10.2 0.0 3.0 3 1 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 KFX96585.1 - 0.022 13.3 0.1 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DUF3237 PF11578.3 KFX96589.1 - 8.8e-28 96.4 0.0 9.8e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.12 KFX96590.1 - 4.6e-38 130.6 0.8 4.8e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 KFX96591.1 - 1.4e-27 96.4 0.1 1.4e-27 96.4 0.1 2.0 2 0 0 2 2 2 1 Leo1-like protein U3_snoRNA_assoc PF08297.6 KFX96591.1 - 2.7 8.2 7.9 9.3 6.5 0.4 2.9 3 0 0 3 3 3 0 U3 snoRNA associated DUF1840 PF08895.6 KFX96591.1 - 6.2 6.8 10.0 0.19 11.7 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) CHORD PF04968.7 KFX96592.1 - 3.4e-50 168.1 18.0 7.6e-26 90.1 4.9 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KFX96592.1 - 2.5e-15 56.7 0.0 3.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 CS domain HeLo PF14479.1 KFX96593.1 - 1e-37 130.0 0.5 9.6e-37 126.7 0.1 2.1 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KFX96593.1 - 0.13 11.3 0.0 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase SURF4 PF02077.10 KFX96594.1 - 6.2e-97 324.1 5.4 7.6e-97 323.8 3.7 1.1 1 0 0 1 1 1 1 SURF4 family WH2 PF02205.15 KFX96594.1 - 3.3e-10 39.2 1.5 1.2e-09 37.4 1.1 2.0 1 0 0 1 1 1 1 WH2 motif NIR_SIR PF01077.17 KFX96595.1 - 0.0072 15.6 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain BOP1NT PF08145.7 KFX96596.1 - 9.4e-105 350.0 8.7 1.3e-104 349.5 6.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KFX96596.1 - 7.9e-29 98.4 5.8 2.9e-11 42.7 0.1 6.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Tannase PF07519.6 KFX96597.1 - 8.8e-80 268.6 0.2 9.9e-79 265.2 0.1 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KFX96597.1 - 5.1e-06 26.5 0.0 3.4e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX96597.1 - 7.3e-05 22.0 0.2 0.2 10.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFX96597.1 - 0.00067 19.2 0.1 0.0017 17.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFX96597.1 - 0.077 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Serglycin PF04360.7 KFX96598.1 - 0.081 12.6 2.1 0.22 11.2 1.0 1.9 2 1 0 2 2 2 0 Serglycin DUF3336 PF11815.3 KFX96599.1 - 7.3e-37 126.0 0.1 2e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFX96599.1 - 2e-15 57.3 0.8 4.8e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase HpcH_HpaI PF03328.9 KFX96600.1 - 1.2e-34 119.1 0.0 1.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Radical_SAM PF04055.16 KFX96600.1 - 0.06 13.5 0.0 0.53 10.4 0.0 2.2 2 1 0 2 2 2 0 Radical SAM superfamily Cellulase PF00150.13 KFX96602.1 - 6.1e-08 32.2 0.0 8.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CPL PF08144.6 KFX96604.1 - 1e-19 70.8 0.2 1.5e-18 67.0 0.0 3.1 3 1 1 4 4 4 1 CPL (NUC119) domain DUF3206 PF11472.3 KFX96604.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) TFIIF_alpha PF05793.7 KFX96604.1 - 0.13 10.6 36.4 0.013 13.8 17.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RWD PF05773.17 KFX96605.1 - 4e-23 81.4 0.7 1.1e-22 80.0 0.0 2.0 2 1 0 2 2 2 1 RWD domain Tfb2 PF03849.9 KFX96605.1 - 0.11 11.1 1.2 0.14 10.7 0.9 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 DUF3818 PF12825.2 KFX96605.1 - 0.22 10.1 3.6 0.29 9.7 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF488 PF04343.8 KFX96605.1 - 0.27 11.6 3.0 0.51 10.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF488 DUF2175 PF09943.4 KFX96605.1 - 7.5 6.6 8.2 6.4 6.9 0.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_12 PF13424.1 KFX96606.1 - 1.5e-12 47.2 0.0 7.1e-07 29.0 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX96606.1 - 7.4e-12 44.2 0.7 4.9e-05 22.9 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX96606.1 - 9e-12 44.4 0.0 2.8e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 KFX96606.1 - 1e-11 45.1 2.4 0.00014 22.4 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96606.1 - 2.2e-10 40.2 5.7 0.059 14.0 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFX96606.1 - 3.6e-10 40.0 5.6 0.0011 19.2 0.1 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX96606.1 - 8.9e-10 37.6 4.8 0.00025 20.6 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX96606.1 - 2.4e-09 36.3 0.0 3.2e-05 23.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX96606.1 - 5.6e-08 32.0 0.2 0.00026 20.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX96606.1 - 0.00013 22.1 2.0 1.4 9.5 0.0 4.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX96606.1 - 0.00061 19.7 0.0 22 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFX96606.1 - 0.00094 19.1 0.8 1 9.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 KFX96606.1 - 0.0023 17.7 0.5 0.022 14.6 0.2 2.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 KFX96606.1 - 0.0026 17.8 0.2 1.8 8.6 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFX96606.1 - 0.011 16.1 10.1 1.9 9.1 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFX96606.1 - 0.018 14.9 12.3 0.038 13.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Rad51 PF08423.6 KFX96608.1 - 8.6e-139 460.6 0.0 1.1e-138 460.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFX96608.1 - 4.8e-14 52.2 0.0 7.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KFX96608.1 - 5.4e-07 29.6 0.6 1.1e-06 28.7 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KFX96608.1 - 1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFX96608.1 - 1.6e-06 27.4 0.0 3.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 KFX96608.1 - 0.064 12.0 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 KFX96608.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Nup160 PF11715.3 KFX96609.1 - 1.2e-133 446.1 0.0 1.7e-133 445.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ribosomal_L29 PF00831.18 KFX96610.1 - 1.4e-17 63.1 0.4 1.4e-17 63.1 0.3 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein SPATA24 PF15175.1 KFX96610.1 - 0.023 14.3 6.0 0.27 10.9 0.3 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Spc42p PF11544.3 KFX96610.1 - 0.22 11.5 2.9 0.25 11.2 1.3 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p V-SNARE_C PF12352.3 KFX96611.1 - 1.1e-14 54.2 0.3 1.1e-14 54.2 0.2 3.2 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus GLTSCR1 PF15249.1 KFX96611.1 - 0.093 12.8 0.5 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region PA28_beta PF02252.13 KFX96611.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit MbeD_MobD PF04899.7 KFX96611.1 - 0.21 11.5 3.6 3.7 7.5 0.0 3.2 2 1 1 3 3 3 0 MbeD/MobD like APG6 PF04111.7 KFX96611.1 - 0.55 9.2 5.7 0.7 8.8 4.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFX96611.1 - 0.59 9.7 11.0 0.54 9.8 6.6 1.6 2 0 0 2 2 2 0 IncA protein Snf7 PF03357.16 KFX96611.1 - 1.2 8.5 5.5 4.6 6.6 1.9 2.3 1 1 1 2 2 2 0 Snf7 DivIC PF04977.10 KFX96611.1 - 1.6 8.2 7.6 23 4.5 0.0 3.3 3 1 1 4 4 4 0 Septum formation initiator FliT PF05400.8 KFX96611.1 - 2.1 8.8 13.0 0.3 11.5 4.9 2.5 2 1 1 3 3 3 0 Flagellar protein FliT V-SNARE PF05008.10 KFX96611.1 - 4.6 7.4 7.4 0.91 9.7 0.4 3.2 3 1 2 5 5 4 0 Vesicle transport v-SNARE protein N-terminus Snapin_Pallidin PF14712.1 KFX96611.1 - 7.9 6.8 8.8 6.3 7.1 4.5 2.0 2 1 0 2 2 2 0 Snapin/Pallidin ATP-synt_10 PF05176.9 KFX96612.1 - 4.8e-65 219.3 0.0 5.4e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Peptidase_C14 PF00656.17 KFX96621.1 - 1.5e-72 244.3 0.0 1.8e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KFX96621.1 - 0.087 12.6 0.5 1.4 8.7 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Microtub_assoc PF07989.6 KFX96622.1 - 2e-27 94.8 10.2 2.7e-27 94.3 2.4 11.3 7 4 4 13 13 13 2 Microtubule associated PACT_coil_coil PF10495.4 KFX96622.1 - 2.7e-19 68.8 0.0 9.6e-19 67.0 0.0 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 KFX96622.1 - 0.00047 20.0 16.8 0.00047 20.0 11.7 11.2 2 2 6 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SGT1 PF07093.6 KFX96623.1 - 1.9e-137 459.1 37.9 7.9e-136 453.8 26.2 2.0 1 1 0 1 1 1 1 SGT1 protein THUMP PF02926.12 KFX96625.1 - 1.1e-07 31.8 0.1 2.6e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.13 KFX96626.1 - 5.5e-34 117.1 0.0 8.1e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX96626.1 - 3.1e-24 85.2 0.0 6.8e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFX96626.1 - 7.8e-14 51.5 0.0 2.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KFX96626.1 - 0.026 13.2 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component OCC1 PF15506.1 KFX96626.1 - 0.15 11.9 1.8 14 5.6 0.0 3.3 3 0 0 3 3 3 0 OCC1 family Pkinase PF00069.20 KFX96627.1 - 1.7e-62 210.9 0.0 6.9e-62 208.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96627.1 - 1.4e-45 155.4 0.0 2.6e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96627.1 - 3.3e-10 39.4 0.0 3.2e-07 29.6 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KFX96627.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribophorin_II PF05817.9 KFX96628.1 - 3.9e-12 45.1 0.1 4.6e-12 44.9 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Iso_dh PF00180.15 KFX96629.1 - 3e-97 325.6 0.0 4.3e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.6 KFX96629.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) MFS_1 PF07690.11 KFX96631.1 - 6.5e-17 61.2 34.7 9.3e-17 60.7 24.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_30 PF02055.11 KFX96632.1 - 2.8e-13 48.9 0.9 6.5e-09 34.5 0.1 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KFX96632.1 - 1.9e-11 43.5 2.0 2.2e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 CBM_1 PF00734.13 KFX96632.1 - 0.19 11.4 14.9 0.56 9.9 10.3 1.9 1 0 0 1 1 1 0 Fungal cellulose binding domain DUF2981 PF11200.3 KFX96632.1 - 0.33 9.9 3.3 0.18 10.8 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) DUF3274 PF11678.3 KFX96633.1 - 0.0075 15.5 0.8 0.016 14.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) O-FucT PF10250.4 KFX96634.1 - 0.0021 17.2 0.0 0.063 12.3 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1030 PF06270.6 KFX96634.1 - 0.12 11.8 0.6 0.33 10.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) Ank_2 PF12796.2 KFX96636.1 - 2.5e-99 325.8 0.7 5.1e-17 61.9 0.2 8.8 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFX96636.1 - 6.3e-79 256.1 0.3 0.0002 20.9 0.0 15.9 16 0 0 16 16 16 14 Ankyrin repeat Ank_3 PF13606.1 KFX96636.1 - 6.2e-70 224.1 0.1 0.00056 19.8 0.0 15.7 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.1 KFX96636.1 - 2.1e-64 212.8 5.5 1.1e-08 35.3 0.0 10.0 2 2 6 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX96636.1 - 7e-62 204.0 9.5 2.6e-08 33.8 0.1 12.3 2 2 12 14 14 14 13 Ankyrin repeats (many copies) NACHT PF05729.7 KFX96636.1 - 3.9e-05 23.3 0.0 8.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX96636.1 - 0.00088 19.4 0.0 0.0037 17.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Met_10 PF02475.11 KFX96637.1 - 0.0016 18.0 0.0 0.0048 16.5 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein hNIFK_binding PF12196.3 KFX96638.1 - 0.00011 21.4 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK Sporozoite_P67 PF05642.6 KFX96638.1 - 0.32 8.8 4.3 0.36 8.6 3.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myb_DNA-bind_6 PF13921.1 KFX96640.1 - 6.6e-07 29.3 0.1 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX96640.1 - 0.02 14.9 3.0 0.048 13.7 1.4 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain HTH_28 PF13518.1 KFX96640.1 - 0.54 10.3 4.1 0.25 11.3 0.7 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain APH PF01636.18 KFX96641.1 - 2.4e-18 66.7 0.1 3.2e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX96641.1 - 0.00023 20.8 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KFX96641.1 - 0.0066 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KFX96641.1 - 0.038 13.3 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family NAD_kinase PF01513.16 KFX96642.1 - 2.2e-68 230.0 0.0 3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 KFX96643.1 - 4.4e-14 52.9 0.2 6.8e-14 52.3 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PTPA PF03095.10 KFX96644.1 - 6.8e-113 376.7 0.0 8.3e-113 376.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FAA_hydrolase PF01557.13 KFX96645.1 - 6.6e-61 205.5 0.0 8.7e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 KFX96646.1 - 1e-16 60.4 1.9 1.3e-16 60.1 1.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX96646.1 - 1.2e-13 51.0 2.5 1.3e-13 50.8 1.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like HSF_DNA-bind PF00447.12 KFX96650.1 - 1e-28 99.5 0.3 2.1e-28 98.5 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Gar1 PF04410.9 KFX96650.1 - 3.2 7.1 5.7 0.2 11.0 0.4 1.6 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region Amidase PF01425.16 KFX96651.1 - 4e-72 243.4 0.1 1.5e-71 241.5 0.0 1.7 1 1 0 1 1 1 1 Amidase Histone PF00125.19 KFX96652.1 - 4.5e-22 77.9 0.0 5.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFX96652.1 - 4.9e-05 23.2 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Neugrin PF06413.6 KFX96654.1 - 1.2e-10 41.5 0.9 1.2e-10 41.5 0.6 2.0 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KFX96654.1 - 0.0001 22.3 4.4 0.0001 22.3 3.0 2.3 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 HLH PF00010.21 KFX96658.1 - 5.4e-09 35.6 0.3 5.4e-09 35.6 0.2 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Med21 PF11221.3 KFX96658.1 - 1 9.2 7.2 0.71 9.8 0.3 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AKAP7_NLS PF10469.4 KFX96660.1 - 1.8e-08 34.3 0.0 1.4e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain T2SM PF04612.7 KFX96666.1 - 1.8 8.3 4.2 0.31 10.8 0.4 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M zf-DHHC PF01529.15 KFX96667.1 - 4.8e-37 127.0 1.0 7.9e-37 126.3 0.3 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase Sugar_tr PF00083.19 KFX96671.1 - 2.5e-68 230.7 7.7 2.8e-68 230.5 5.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96671.1 - 1.8e-24 86.1 2.5 2.6e-24 85.5 1.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX96671.1 - 4.4e-06 25.3 2.0 1e-05 24.1 1.4 1.6 1 0 0 1 1 1 1 MFS/sugar transport protein Tmemb_170 PF10190.4 KFX96671.1 - 0.00067 19.6 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Putative transmembrane protein 170 OATP PF03137.15 KFX96671.1 - 0.0038 15.3 2.0 0.0052 14.8 0.6 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family EpsG PF14897.1 KFX96671.1 - 0.081 11.8 4.7 0.031 13.2 0.4 2.0 2 0 0 2 2 2 0 EpsG family AAA_10 PF12846.2 KFX96672.1 - 6.8e-09 35.5 0.0 4.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 KFX96672.1 - 0.00033 20.1 0.3 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KFX96672.1 - 0.00071 19.7 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX96672.1 - 0.01 15.2 0.0 0.032 13.7 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KFX96672.1 - 0.041 12.9 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_34 PF13872.1 KFX96672.1 - 0.042 12.6 0.0 0.076 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF3437 PF11919.3 KFX96672.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF87 PF01935.12 KFX96672.1 - 0.17 11.6 0.0 2.6 7.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 TauD PF02668.11 KFX96674.1 - 3.3e-53 180.9 0.4 4.3e-53 180.6 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aldolase_II PF00596.16 KFX96675.1 - 3.7e-45 153.8 0.3 3.7e-45 153.8 0.2 1.6 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.11 KFX96675.1 - 4.5e-13 48.6 26.7 7.4e-13 47.9 18.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Dynamin_M PF01031.15 KFX96679.1 - 3e-114 380.7 0.0 7.4e-114 379.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFX96679.1 - 4.2e-56 189.3 0.8 7.1e-56 188.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KFX96679.1 - 0.00031 20.6 0.2 0.0028 17.5 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX96679.1 - 0.0093 16.4 0.0 0.032 14.7 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein zf-CCHC_4 PF14392.1 KFX96679.1 - 0.085 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle SH3_9 PF14604.1 KFX96680.1 - 5.5e-31 105.9 2.9 8e-16 57.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFX96680.1 - 2.1e-26 91.0 5.4 5.7e-14 51.2 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KFX96680.1 - 6.9e-16 57.4 0.2 3.8e-07 29.4 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KFX96680.1 - 8.1e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.2 KFX96681.1 - 0.0036 17.0 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX96681.1 - 0.036 13.7 0.1 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain Tyrosinase PF00264.15 KFX96682.1 - 2.9e-47 161.6 2.6 3.9e-47 161.2 1.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3405 PF11885.3 KFX96694.1 - 1.4e-109 366.5 0.2 1.8e-109 366.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Nefa_Nip30_N PF10187.4 KFX96695.1 - 5.2e-29 100.4 5.2 5.2e-29 100.4 3.6 2.6 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Ribosomal_L30_N PF08079.7 KFX96695.1 - 0.028 14.4 1.7 0.028 14.4 1.1 3.0 2 1 1 3 3 3 0 Ribosomal L30 N-terminal domain DUF572 PF04502.8 KFX96695.1 - 0.074 12.2 16.2 0.087 12.0 11.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2613 PF11021.3 KFX96695.1 - 0.13 12.0 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4614 PF15391.1 KFX96695.1 - 0.22 11.2 4.8 0.065 12.9 0.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4614) UVR PF02151.14 KFX96695.1 - 1.4 8.5 8.5 0.13 11.8 2.0 2.3 2 0 0 2 2 2 0 UvrB/uvrC motif Aldo_ket_red PF00248.16 KFX96696.1 - 5.3e-51 173.0 0.0 6.8e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PI-PLC-X PF00388.14 KFX96697.1 - 1.2e-14 53.9 0.0 2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 KFX96698.1 - 0.001 18.9 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L10 Sterol_MT_C PF08498.5 KFX96698.1 - 0.094 12.6 0.5 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal Glycos_transf_3 PF00591.16 KFX96699.1 - 1.6e-63 214.5 0.0 2.4e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KFX96699.1 - 3.2e-16 58.6 0.2 7.5e-16 57.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 KFX96700.1 - 6.2e-18 63.9 4.9 7.8e-18 63.6 3.4 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFX96700.1 - 0.0027 17.4 0.3 0.0036 17.0 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon A2L_zn_ribbon PF08792.5 KFX96700.1 - 0.004 16.5 0.6 0.3 10.6 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain DUF2197 PF09963.4 KFX96700.1 - 0.0083 16.0 1.8 0.51 10.3 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) TFIIS_C PF01096.13 KFX96700.1 - 0.012 15.2 0.7 3 7.5 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HypA PF01155.14 KFX96700.1 - 0.023 14.3 0.3 0.028 14.0 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GFA PF04828.9 KFX96700.1 - 0.027 14.4 0.2 2.5 8.1 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 KFX96700.1 - 0.036 14.0 1.5 0.059 13.3 1.1 1.4 1 1 0 1 1 1 0 Zinc ribbon domain DUF951 PF06107.6 KFX96700.1 - 0.11 12.0 0.2 2 7.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Zn_ribbon_recom PF13408.1 KFX96700.1 - 0.16 12.2 2.1 2.2 8.6 0.3 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain RRN7 PF11781.3 KFX96700.1 - 0.21 11.0 2.4 0.45 10.0 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 HEM4 PF02602.10 KFX96703.1 - 0.001 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.8 KFX96704.1 - 2.2e-05 24.2 0.3 8e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family TLD PF07534.11 KFX96705.1 - 1e-26 93.5 0.0 1e-14 54.7 0.0 2.2 2 0 0 2 2 2 2 TLD Xpo1 PF08389.7 KFX96706.1 - 2.2e-07 30.8 0.7 2.5e-05 24.2 0.1 2.9 2 0 0 2 2 2 2 Exportin 1-like protein DUF1767 PF08585.7 KFX96707.1 - 2.1e-07 31.1 0.0 3.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 KFX96708.1 - 4.3e-28 96.9 1.1 6.8e-28 96.3 0.1 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 KFX96708.1 - 4.5e-08 31.9 1.9 6.6e-08 31.3 1.3 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 KFX96708.1 - 0.0047 16.8 0.1 0.014 15.3 0.0 1.7 1 1 1 2 2 2 1 Golgi transport complex subunit 5 Sec5 PF15469.1 KFX96708.1 - 0.014 15.1 0.1 0.045 13.4 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex component Sec5 BBP1_C PF15272.1 KFX96708.1 - 0.015 14.8 0.3 0.028 13.9 0.1 1.5 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal SSFA2_C PF14723.1 KFX96708.1 - 0.016 14.9 0.6 0.039 13.6 0.4 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus UBN_AB PF14075.1 KFX96708.1 - 0.02 14.5 1.4 0.031 13.9 1.0 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF365 PF04033.7 KFX96708.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Stimulus_sens_1 PF13756.1 KFX96708.1 - 0.041 14.2 0.6 0.18 12.1 0.1 2.1 1 1 1 2 2 2 0 Stimulus-sensing domain NYD-SP28_assoc PF14775.1 KFX96708.1 - 0.051 13.2 0.5 0.13 11.9 0.3 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain ATP-synt_ab PF00006.20 KFX96708.1 - 0.06 12.8 0.1 0.088 12.2 0.1 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Toxin_39 PF15500.1 KFX96708.1 - 2.2 8.4 6.0 8.2 6.6 0.0 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin FUSC PF04632.7 KFX96708.1 - 5.1 5.3 7.8 9.4 4.5 5.3 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family NIF3 PF01784.13 KFX96709.1 - 4.2e-57 193.4 0.0 5.4e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 KFX96710.1 - 4.1e-21 74.7 0.0 5.7e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Pro_CA PF00484.14 KFX96711.1 - 1.1e-28 100.1 0.0 1.4e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Adaptin_N PF01602.15 KFX96713.1 - 2e-149 498.3 4.1 2.8e-149 497.8 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFX96713.1 - 1.5e-25 90.0 0.3 5.3e-24 85.0 0.1 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFX96713.1 - 4.3e-18 65.3 0.9 3.7e-06 27.1 0.0 5.3 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.17 KFX96713.1 - 8.3e-12 44.1 4.3 0.016 15.2 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KFX96713.1 - 0.00075 19.9 0.7 0.89 10.1 0.0 5.1 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KFX96713.1 - 0.0012 18.2 0.3 2.1 7.6 0.0 3.5 3 1 1 4 4 4 2 CLASP N terminal UNC45-central PF11701.3 KFX96713.1 - 0.0037 16.9 0.7 2.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.18 KFX96713.1 - 0.027 14.2 0.3 8.3 6.4 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KFX96713.1 - 0.033 13.9 0.0 0.55 9.9 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Rep_fac_C PF08542.6 KFX96713.1 - 0.11 12.4 0.1 21 5.1 0.0 3.1 1 1 1 2 2 2 0 Replication factor C C-terminal domain TPR_11 PF13414.1 KFX96714.1 - 1.4e-45 152.7 30.0 3.2e-06 26.6 0.0 12.3 9 4 3 12 12 12 10 TPR repeat TPR_16 PF13432.1 KFX96714.1 - 3.1e-37 126.4 36.9 3.6e-06 27.4 2.1 13.3 13 2 2 15 15 12 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFX96714.1 - 6.4e-29 97.5 40.9 0.0077 16.0 0.0 16.2 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96714.1 - 4.3e-28 95.2 33.4 0.007 16.8 0.0 15.4 11 5 5 16 16 15 8 Tetratricopeptide repeat TPR_17 PF13431.1 KFX96714.1 - 5.2e-27 91.7 16.4 0.067 13.4 0.0 16.0 16 1 0 16 16 16 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX96714.1 - 5.7e-26 90.6 20.8 0.0011 19.2 0.0 11.4 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.1 KFX96714.1 - 5.1e-23 80.8 23.0 1.6e-05 24.7 0.0 11.6 7 6 7 14 14 14 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFX96714.1 - 8.2e-23 79.0 23.0 0.0035 16.9 0.0 13.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFX96714.1 - 7.9e-17 59.7 10.9 0.051 13.3 0.0 11.5 11 1 1 12 12 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFX96714.1 - 4.4e-12 45.6 22.3 0.02 15.3 0.0 13.0 15 0 0 15 15 12 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX96714.1 - 4.4e-11 41.7 20.6 0.1 12.4 0.0 11.9 13 1 0 13 13 11 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFX96714.1 - 2e-08 33.9 13.4 0.00073 19.3 0.1 6.8 6 1 1 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX96714.1 - 1.2e-05 25.3 18.4 0.014 15.4 0.1 7.5 6 4 2 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KFX96714.1 - 1.5e-05 25.0 9.4 2.9 8.0 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat ChAPs PF09295.5 KFX96714.1 - 0.0047 15.7 0.3 6.4 5.4 0.0 4.2 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) Tcf25 PF04910.9 KFX96714.1 - 0.0057 15.6 0.1 0.48 9.3 0.0 3.1 3 0 0 3 3 3 1 Transcriptional repressor TCF25 DUF2225 PF09986.4 KFX96714.1 - 0.0058 16.1 0.6 2.8 7.3 0.0 2.9 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_WDAD PF04053.9 KFX96714.1 - 0.0083 14.9 0.0 0.022 13.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer WD associated region TOM20_plant PF06552.7 KFX96714.1 - 2.6 7.5 8.1 7.4 6.1 0.0 4.6 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Cellulase PF00150.13 KFX96715.1 - 9.8e-15 54.4 1.8 3.7e-09 36.2 0.3 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KFX96715.1 - 0.055 12.8 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Dynamin_N PF00350.18 KFX96716.1 - 2.5e-30 105.5 0.0 5.2e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFX96716.1 - 3.5e-17 62.1 1.0 2e-16 59.6 0.7 2.0 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KFX96716.1 - 0.00066 19.6 0.0 0.0029 17.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 KFX96716.1 - 0.021 14.7 0.0 0.062 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFX96716.1 - 0.025 15.0 0.1 0.092 13.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Imm27 PF15573.1 KFX96716.1 - 0.096 11.8 0.8 0.17 11.0 0.2 1.7 2 0 0 2 2 2 0 Immunity protein 27 AAA_29 PF13555.1 KFX96716.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BTB PF00651.26 KFX96717.1 - 1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DNA_primase_S PF01896.14 KFX96718.1 - 2.9e-55 186.0 0.1 4.7e-55 185.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF2410 PF10307.4 KFX96719.1 - 5.7e-79 264.1 0.0 7.6e-79 263.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) CPSF100_C PF13299.1 KFX96721.1 - 1.8e-41 142.0 0.3 3.9e-41 140.9 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KFX96721.1 - 9.1e-26 90.2 0.0 3.1e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 KFX96721.1 - 2.2e-05 24.1 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KFX96721.1 - 0.032 13.8 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Sec23_trunk PF04811.10 KFX96722.1 - 1.6e-54 184.8 0.0 1.2e-53 181.9 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFX96722.1 - 2e-26 91.3 0.0 3.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFX96722.1 - 8.7e-18 64.6 0.0 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFX96722.1 - 1.5e-16 59.6 5.2 4.1e-16 58.2 3.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFX96722.1 - 1.9e-08 33.8 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat CmcH_NodU PF02543.10 KFX96735.1 - 1.1e-85 287.9 0.0 4e-84 282.8 0.0 2.5 2 1 0 2 2 2 1 Carbamoyltransferase Peptidase_M22 PF00814.20 KFX96735.1 - 0.0031 17.0 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Glycoprotease family AMP-binding PF00501.23 KFX96736.1 - 3.9e-79 265.9 0.0 4.6e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX96736.1 - 1.1e-06 29.4 0.1 4e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 KFX96737.1 - 1.2e-63 215.2 0.0 1.6e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.1 KFX96738.1 - 2.7e-10 40.5 0.0 1.7e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX96738.1 - 0.00023 21.6 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX96738.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SUR7 PF06687.7 KFX96741.1 - 2.4e-30 105.6 6.4 3.4e-30 105.1 4.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KFX96741.1 - 0.1 12.2 17.1 0.22 11.2 11.8 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Herpes_pp38 PF04846.8 KFX96741.1 - 0.18 11.1 0.1 0.18 11.1 0.0 2.4 3 1 0 3 3 3 0 Herpesvirus pp38 phosphoprotein DUF805 PF05656.9 KFX96741.1 - 0.19 11.5 9.4 0.11 12.3 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) WBP-1 PF11669.3 KFX96741.1 - 4.6 7.3 6.3 1.2 9.2 0.5 2.4 2 1 0 2 2 2 0 WW domain-binding protein 1 DUF2650 PF10853.3 KFX96741.1 - 7.3 6.1 6.8 0.54 9.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) AhpC-TSA_2 PF13911.1 KFX96744.1 - 1.1e-09 38.1 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFX96744.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family HpaP PF09483.5 KFX96744.1 - 0.84 9.5 9.4 1.1 9.2 6.5 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Peptidase_C97 PF05903.9 KFX96745.1 - 2.1e-06 27.5 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.7 KFX96745.1 - 0.095 12.6 0.5 0.24 11.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF778) LRAT PF04970.8 KFX96745.1 - 0.13 12.1 3.4 0.2 11.6 0.8 2.3 2 1 0 2 2 2 0 Lecithin retinol acyltransferase COPIIcoated_ERV PF07970.7 KFX96746.1 - 9.6e-37 126.7 0.3 1.5e-36 126.1 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFX96746.1 - 3.3e-19 68.6 0.0 6.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SNARE PF05739.14 KFX96747.1 - 2.1e-15 56.1 0.7 2.1e-15 56.1 0.5 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFX96747.1 - 1.8e-07 31.2 4.7 3.1e-07 30.5 1.2 2.2 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 KFX96747.1 - 0.00038 20.4 2.3 0.00038 20.4 1.6 2.3 2 0 0 2 2 2 1 Syntaxin-like protein BLOC1_2 PF10046.4 KFX96747.1 - 0.0086 16.1 4.1 0.21 11.7 0.0 3.1 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.6 KFX96747.1 - 0.031 13.6 2.7 0.047 13.0 0.9 2.0 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Bac_export_3 PF01313.14 KFX96747.1 - 0.037 13.7 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 Tad PF13400.1 KFX96747.1 - 0.062 13.3 0.4 0.062 13.3 0.3 3.4 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like ETRAMP PF09716.5 KFX96747.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TMCO5 PF14992.1 KFX96747.1 - 0.14 11.3 5.9 1.3 8.1 0.4 2.1 2 0 0 2 2 2 0 TMCO5 family GP41 PF00517.12 KFX96747.1 - 0.43 10.0 3.3 6.9 6.1 0.3 2.4 2 1 0 2 2 2 0 Retroviral envelope protein HlyD_2 PF12700.2 KFX96747.1 - 1.8 7.6 6.6 2.1 7.4 4.1 1.5 1 1 0 1 1 1 0 HlyD family secretion protein V-SNARE PF05008.10 KFX96747.1 - 2.5 8.3 9.5 0.51 10.5 0.3 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.5 KFX96747.1 - 3.4 7.7 7.6 20 5.3 0.1 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Brix PF04427.13 KFX96748.1 - 8e-47 159.3 0.8 1.1e-46 158.9 0.6 1.2 1 0 0 1 1 1 1 Brix domain ABC_tran PF00005.22 KFX96759.1 - 1.6e-49 167.7 0.0 5.3e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX96759.1 - 1.7e-28 99.7 18.8 3.1e-14 53.0 3.0 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KFX96759.1 - 1.3e-10 40.8 0.0 0.0016 17.7 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX96759.1 - 6.5e-06 26.3 2.5 0.72 9.7 0.0 4.5 3 2 1 4 4 3 1 AAA domain T2SE PF00437.15 KFX96759.1 - 1.3e-05 24.2 0.0 0.014 14.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 KFX96759.1 - 2.4e-05 23.8 0.1 0.05 12.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KFX96759.1 - 5.5e-05 23.5 0.1 0.0041 17.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KFX96759.1 - 0.00014 21.2 0.2 0.62 9.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX96759.1 - 0.00053 20.0 5.0 0.16 11.9 0.1 3.4 4 0 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 KFX96759.1 - 0.0014 19.0 0.3 3.7 8.0 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KFX96759.1 - 0.0033 16.6 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX96759.1 - 0.0043 17.1 0.1 4.7 7.3 0.0 3.5 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KFX96759.1 - 0.007 16.2 1.7 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KFX96759.1 - 0.0083 15.2 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 KFX96759.1 - 0.0091 15.9 0.1 0.54 10.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KFX96759.1 - 0.022 14.2 0.1 5.6 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain DUF2075 PF09848.4 KFX96759.1 - 0.061 12.2 0.1 0.59 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 KFX96759.1 - 0.6 9.5 2.9 1.5 8.2 0.5 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KFX96759.1 - 1.1 8.8 3.8 1.4 8.5 0.1 2.8 3 0 0 3 3 3 0 NACHT domain Raffinose_syn PF05691.7 KFX96760.1 - 3.5e-49 167.0 1.5 8.2e-47 159.2 1.2 2.3 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KFX96760.1 - 4.2e-06 25.7 0.5 7.2e-06 24.9 0.3 1.3 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.20 KFX96761.1 - 6e-76 255.3 0.0 8e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LigD_N PF13298.1 KFX96762.1 - 3.9e-20 71.8 0.0 1.1e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) AA_permease PF00324.16 KFX96766.1 - 3e-140 467.7 36.1 3.6e-140 467.4 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX96766.1 - 6.7e-39 133.6 38.6 9.1e-39 133.1 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 KFX96767.1 - 7e-69 231.8 0.0 1.2e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96767.1 - 1.2e-42 145.8 0.0 1.6e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96767.1 - 9.5e-12 44.4 0.0 2.4e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFX96767.1 - 0.0043 16.8 9.5 1.5 8.4 0.1 3.9 2 2 2 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.9 KFX96767.1 - 0.015 14.3 0.0 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.1 KFX96768.1 - 7.4e-06 25.5 7.8 7.4e-06 25.5 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX96768.1 - 8.9e-06 25.6 12.0 8.9e-06 25.6 8.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX96768.1 - 1.4e-05 24.6 10.5 1.4e-05 24.6 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX96768.1 - 3e-05 23.6 9.0 3e-05 23.6 6.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFX96768.1 - 3e-05 23.7 12.1 3e-05 23.7 8.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFX96768.1 - 4.6e-05 23.2 12.2 4.6e-05 23.2 8.4 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX96768.1 - 0.00084 19.0 4.6 0.00084 19.0 3.2 1.8 2 0 0 2 2 1 1 RING-type zinc-finger UPF0547 PF10571.4 KFX96768.1 - 0.047 13.3 0.7 0.047 13.3 0.5 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Rhabdo_ncap PF00945.13 KFX96768.1 - 0.092 11.3 0.5 7.8 4.9 0.0 2.4 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein PhnA_Zn_Ribbon PF08274.7 KFX96768.1 - 0.18 11.6 5.1 0.46 10.3 0.1 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.2 KFX96768.1 - 0.93 9.3 15.0 0.32 10.8 0.8 2.8 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 KFX96768.1 - 3 7.4 7.8 5.6 6.6 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFX96768.1 - 4.1 7.1 7.6 9.6 5.9 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain NatB_MDM20 PF09797.4 KFX96769.1 - 1.1e-55 188.8 0.0 2.5e-55 187.6 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 KFX96769.1 - 0.00082 19.6 6.1 0.43 10.9 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96769.1 - 0.15 12.8 0.8 35 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX96769.1 - 3.1 8.5 7.9 1.6 9.5 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ilm1 PF10311.4 KFX96770.1 - 9.3e-44 148.8 0.2 1.1e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 M20_dimer PF07687.9 KFX96771.1 - 2.3e-21 75.6 0.0 4.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 KFX96771.1 - 1.3e-17 63.9 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HAD PF12710.2 KFX96771.1 - 3.3e-09 37.2 0.0 6.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.12 KFX96771.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Prenyltrans PF00432.16 KFX96772.1 - 5.2e-35 118.6 4.8 2.8e-08 33.1 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFX96772.1 - 1.2e-24 86.8 0.0 3.4e-13 49.9 0.0 4.3 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFX96772.1 - 1.9e-08 34.2 0.0 0.00075 19.4 0.0 4.2 2 1 1 3 3 3 2 Prenyltransferase-like ThiF PF00899.16 KFX96773.1 - 2.8e-42 143.7 0.0 5.1e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KFX96773.1 - 2.8e-22 78.0 0.9 4.9e-21 74.1 0.6 2.4 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KFX96773.1 - 8.5e-13 48.6 0.0 1.6e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KFX96773.1 - 0.00014 21.9 0.1 0.0022 18.1 0.1 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFX96773.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 KFX96773.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX96773.1 - 0.18 10.6 1.2 0.29 9.9 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pam17 PF08566.5 KFX96774.1 - 3e-66 222.3 0.0 4.2e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 EVI2A PF05399.6 KFX96774.1 - 0.66 9.1 6.2 1 8.5 4.3 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Ribonuclease_3 PF00636.21 KFX96775.1 - 2.7e-41 140.5 0.0 3.9e-21 75.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFX96775.1 - 1.9e-26 92.5 0.0 1.4e-11 44.4 0.0 3.9 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KFX96775.1 - 1.2e-23 82.6 0.0 3e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 KFX96775.1 - 7.8e-18 64.5 0.0 1.4e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX96775.1 - 1.5e-13 50.4 0.0 3.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX96775.1 - 2.3e-12 47.1 0.0 6.1e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFX96775.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Glyco_trans_2_3 PF13632.1 KFX96778.1 - 3.9e-16 59.3 0.5 3.9e-16 59.3 0.4 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 VWA_3 PF13768.1 KFX96781.1 - 3.2e-24 85.3 0.0 6.7e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KFX96781.1 - 2.4e-17 62.6 0.5 7e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFX96781.1 - 8.8e-09 35.3 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFX96781.1 - 1.3e-08 35.1 0.0 4.6e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 KFX96781.1 - 0.00011 21.5 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 KFX96781.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KFX96781.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Frag1 PF10277.4 KFX96785.1 - 2.6e-43 147.9 9.6 5.9e-43 146.8 6.7 1.6 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 KFX96786.1 - 2.1e-13 49.8 0.1 2.8e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Pex14_N PF04695.8 KFX96786.1 - 0.027 14.5 0.2 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSA-2c PF12238.3 KFX96786.1 - 0.076 12.6 0.2 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Kinesin PF00225.18 KFX96801.1 - 5.2e-31 107.5 0.0 8.4e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain ADIP PF11559.3 KFX96801.1 - 0.037 13.9 0.7 0.18 11.7 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 KFX96801.1 - 3.1 7.8 7.4 4.4 7.3 3.0 2.2 2 0 0 2 2 2 0 DivIVA protein ketoacyl-synt PF00109.21 KFX96803.1 - 2.4e-73 246.7 0.1 4.9e-72 242.4 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX96803.1 - 4e-63 213.6 0.6 7.1e-63 212.8 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFX96803.1 - 1.4e-50 171.5 0.0 3.9e-50 170.0 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KFX96803.1 - 4.4e-46 157.3 0.0 6.6e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFX96803.1 - 8.3e-40 136.4 2.1 1.1e-39 135.9 0.0 2.4 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFX96803.1 - 1.4e-35 121.7 0.0 6e-35 119.6 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFX96803.1 - 1.6e-19 70.2 0.0 4.9e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFX96803.1 - 6e-17 61.4 0.0 2.2e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFX96803.1 - 7.2e-12 45.3 0.0 2.9e-11 43.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX96803.1 - 2.2e-10 40.3 0.0 8.3e-10 38.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX96803.1 - 7.1e-09 36.2 0.1 6.9e-08 33.0 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX96803.1 - 1e-07 32.3 0.0 3.3e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFX96803.1 - 8e-06 26.0 1.0 2.4e-05 24.4 0.2 2.4 2 0 0 2 2 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 KFX96803.1 - 2.5e-05 23.5 0.0 6.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KFX96803.1 - 0.00019 20.5 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 KFX96803.1 - 0.0035 17.0 0.1 0.0089 15.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.10 KFX96803.1 - 0.025 13.4 0.0 0.054 12.3 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.4 KFX96803.1 - 0.041 13.3 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 1 0 Putative methyltransferase Shikimate_DH PF01488.15 KFX96803.1 - 0.043 13.9 0.0 0.22 11.6 0.0 2.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ACP_syn_III PF08545.5 KFX96803.1 - 0.12 12.0 1.5 0.34 10.5 0.1 2.5 3 0 0 3 3 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Transferase PF02458.10 KFX96804.1 - 1.9e-30 105.6 0.0 3.2e-30 104.9 0.0 1.3 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 KFX96804.1 - 0.034 12.9 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Condensation domain CHZ PF09649.5 KFX96804.1 - 0.13 11.5 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ DUF2264 PF10022.4 KFX96806.1 - 1.1e-122 409.1 0.0 1.4e-122 408.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Fungal_trans PF04082.13 KFX96807.1 - 2.8e-17 62.4 0.2 5.5e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96807.1 - 8e-07 28.8 10.4 1.7e-06 27.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KFX96807.1 - 0.37 9.5 3.4 0.8 8.4 2.4 1.5 1 0 0 1 1 1 0 Clusterin Glyco_hydro_88 PF07470.8 KFX96808.1 - 1.9e-13 50.1 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 KFX96809.1 - 4.7e-27 94.6 18.6 6.8e-26 90.8 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF423 PF04241.10 KFX96809.1 - 4.5 7.2 6.6 28 4.7 1.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF2823 PF11034.3 KFX96810.1 - 5.5e-34 116.1 11.7 6.1e-34 115.9 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) CSF-1 PF05337.6 KFX96810.1 - 0.023 14.0 0.7 0.023 14.0 0.5 1.1 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) HATPase_c PF02518.21 KFX96811.1 - 8.3e-19 67.3 0.1 1.7e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX96811.1 - 5.2e-16 58.6 0.0 5.2e-12 45.7 0.0 3.6 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 KFX96811.1 - 9.4e-14 51.1 0.0 3.7e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KFX96811.1 - 0.0002 21.4 0.4 0.0022 18.0 0.1 2.9 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.1 KFX96811.1 - 0.0069 16.8 0.0 0.022 15.2 0.0 2.0 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.1 KFX96811.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain F-box-like PF12937.2 KFX96812.1 - 1.3e-05 24.7 0.2 4.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like FAD_binding_4 PF01565.18 KFX96813.1 - 2.1e-17 62.8 2.1 5e-17 61.6 1.5 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX96813.1 - 3.5e-07 30.0 0.0 6.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3237 PF11578.3 KFX96814.1 - 4.4e-06 26.0 0.1 6.2e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) OPT PF03169.10 KFX96815.1 - 5.9e-128 428.0 44.3 7e-128 427.7 30.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.4 KFX96815.1 - 0.0091 14.6 1.1 0.022 13.3 0.7 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4181 PF13789.1 KFX96815.1 - 0.11 12.3 5.5 1.8 8.5 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF3093 PF11292.3 KFX96815.1 - 0.15 11.8 3.1 1.3 8.7 1.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) Pectate_lyase PF03211.8 KFX96816.1 - 2.3e-61 206.9 6.2 2.8e-61 206.6 4.3 1.1 1 0 0 1 1 1 1 Pectate lyase Herpes_LMP1 PF05297.6 KFX96817.1 - 0.5 9.2 2.5 0.53 9.1 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) bZIP_2 PF07716.10 KFX96819.1 - 0.83 9.5 6.6 2.2 8.1 0.8 3.3 2 0 0 2 2 2 0 Basic region leucine zipper Cep57_CLD_2 PF14197.1 KFX96819.1 - 5 7.1 11.2 97 3.0 7.8 2.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Glyco_hydro_16 PF00722.16 KFX96820.1 - 2.4e-20 72.6 0.2 4.7e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nucleoporin_FG PF13634.1 KFX96825.1 - 6.4e-17 61.8 125.7 2.3e-06 27.8 25.0 4.3 1 1 4 5 5 5 5 Nucleoporin FG repeat region F-box-like PF12937.2 KFX96828.1 - 0.00058 19.5 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like RPN7 PF10602.4 KFX96828.1 - 0.00097 18.5 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KFX96828.1 - 0.0054 17.0 0.7 0.26 11.6 0.5 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat Pkinase PF00069.20 KFX96829.1 - 6.1e-45 153.4 0.0 8.9e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96829.1 - 6.6e-18 64.7 0.0 9.9e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96829.1 - 0.041 12.8 0.0 0.15 10.9 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Cir_N PF10197.4 KFX96830.1 - 0.0045 16.9 0.9 0.0045 16.9 0.6 3.6 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 KFX96831.1 - 1e-52 177.8 0.0 2.1e-38 131.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFX96831.1 - 1.4e-11 44.1 0.0 3.4e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KFX96831.1 - 1.5e-10 40.5 0.4 4.1e-09 35.9 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KFX96831.1 - 2e-10 40.8 0.3 0.0012 18.9 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX96831.1 - 4.9e-09 36.1 0.0 0.00043 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX96831.1 - 6.1e-09 36.1 0.1 0.0042 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KFX96831.1 - 2e-08 35.0 0.0 0.0087 16.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KFX96831.1 - 1.6e-07 31.1 0.0 0.0019 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFX96831.1 - 1.9e-07 30.7 0.1 0.034 13.8 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain TIP49 PF06068.8 KFX96831.1 - 1.9e-07 30.1 0.0 0.005 15.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 KFX96831.1 - 1.9e-07 31.1 0.0 0.019 15.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 KFX96831.1 - 3.1e-07 29.6 0.0 0.0088 15.1 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KFX96831.1 - 3.8e-07 30.4 0.0 0.013 15.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.9 KFX96831.1 - 5.5e-07 29.6 0.1 0.00052 19.9 0.1 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFX96831.1 - 2.3e-06 27.5 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFX96831.1 - 2.5e-06 27.0 0.4 0.04 13.3 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein NACHT PF05729.7 KFX96831.1 - 6.9e-06 25.8 0.7 0.0086 15.7 0.1 3.4 2 2 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 KFX96831.1 - 9.3e-06 25.2 0.0 0.065 12.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFX96831.1 - 9.4e-06 24.9 0.1 0.015 14.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KFX96831.1 - 4.5e-05 22.6 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KFX96831.1 - 9.2e-05 21.9 0.1 0.54 9.6 0.0 3.2 2 1 1 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KFX96831.1 - 9.4e-05 22.2 1.1 1.2 8.7 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 KFX96831.1 - 0.00012 21.0 0.0 0.34 9.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 KFX96831.1 - 0.00012 22.3 0.1 0.3 11.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.1 KFX96831.1 - 0.0002 20.9 0.2 0.2 11.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KFX96831.1 - 0.00031 19.9 0.4 0.026 13.6 0.2 2.4 2 0 0 2 2 2 1 KaiC PhoH PF02562.11 KFX96831.1 - 0.0004 19.6 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UPF0079 PF02367.12 KFX96831.1 - 0.0014 18.2 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KFX96831.1 - 0.0022 17.9 0.0 0.74 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KFX96831.1 - 0.0036 16.3 0.0 0.35 9.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KFX96831.1 - 0.009 15.8 0.2 3.7 7.3 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFX96831.1 - 0.013 15.0 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KFX96831.1 - 0.015 15.3 0.0 8.3 6.4 0.0 2.8 4 0 0 4 4 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFX96831.1 - 0.015 14.1 0.0 0.31 9.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 KFX96831.1 - 0.02 14.3 0.1 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.1 KFX96831.1 - 0.024 14.2 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KFX96831.1 - 0.031 13.7 0.1 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 KFX96831.1 - 0.04 13.5 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFX96831.1 - 0.042 12.7 0.0 7.9 5.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.24 KFX96831.1 - 0.05 13.0 0.6 8.7 5.7 0.0 3.6 2 2 1 3 3 3 0 DEAD/DEAH box helicase AAA_10 PF12846.2 KFX96831.1 - 0.082 12.3 0.1 1.6 8.0 0.1 2.4 2 1 0 2 2 2 0 AAA-like domain CPT PF07931.7 KFX96831.1 - 0.083 12.5 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.8 KFX96831.1 - 0.086 11.7 0.0 4.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.5 KFX96831.1 - 0.1 11.8 0.0 0.65 9.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IPT PF01745.11 KFX96831.1 - 0.15 11.2 0.1 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase RasGEF PF00617.14 KFX96832.1 - 4.4e-40 137.4 0.2 6.6e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFX96832.1 - 4.2e-08 33.2 0.1 1.2e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Nucleoplasmin PF03066.10 KFX96838.1 - 0.028 13.9 0.5 0.032 13.7 0.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KFX96838.1 - 0.11 12.7 4.2 0.16 12.2 2.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 KFX96838.1 - 0.19 10.9 3.6 0.22 10.7 2.5 1.1 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.7 KFX96838.1 - 0.43 8.8 8.6 0.51 8.6 5.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KFX96838.1 - 1.7 6.4 4.6 2.1 6.1 3.2 1.0 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.8 KFX96838.1 - 2.1 6.1 4.9 2.7 5.7 3.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HAD PF12710.2 KFX96847.1 - 2.2e-12 47.5 0.0 3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFX96847.1 - 6.2e-06 26.5 0.0 2.1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFX96847.1 - 0.00019 20.6 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 KFX96847.1 - 0.027 14.8 0.0 0.08 13.3 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFX96847.1 - 0.028 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.6 KFX96848.1 - 2.2e-86 288.7 2.1 3.1e-86 288.2 1.5 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 KFX96848.1 - 0.019 14.5 0.9 0.033 13.7 0.6 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein DUF605 PF04652.11 KFX96848.1 - 0.86 8.9 12.3 1.4 8.2 8.5 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KFX96850.1 - 9.1e-64 215.0 0.0 1.6e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96850.1 - 7.3e-37 126.8 0.0 1.3e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KFX96850.1 - 2.2e-27 94.5 19.0 9.1e-15 54.1 2.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KFX96850.1 - 2.6e-19 68.6 29.0 2.9e-11 42.9 6.6 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFX96850.1 - 1e-13 51.5 3.8 2.9e-13 50.0 2.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFX96850.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FYVE_2 PF02318.11 KFX96850.1 - 0.53 10.1 18.2 3.4 7.6 2.9 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger Acyl-CoA_dh_1 PF00441.19 KFX96851.1 - 2e-41 141.5 3.5 3.5e-41 140.7 2.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX96851.1 - 5.7e-28 97.7 0.3 1.3e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFX96851.1 - 3.9e-17 61.5 0.1 7.2e-17 60.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX96851.1 - 4.7e-17 62.4 0.7 1e-16 61.3 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosom_S12_S23 PF00164.20 KFX96852.1 - 6.6e-40 135.3 2.3 8.2e-40 135.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 KFX96853.1 - 7.5e-141 468.8 9.9 9e-141 468.5 6.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase HNH_3 PF13392.1 KFX96853.1 - 0.058 12.8 1.6 0.084 12.2 0.1 2.1 2 0 0 2 2 2 0 HNH endonuclease PAT1 PF09770.4 KFX96854.1 - 1.6e-249 830.4 30.2 2e-249 830.1 20.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DAHP_synth_2 PF01474.11 KFX96861.1 - 6.4e-190 631.1 0.0 7.3e-190 630.9 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family HIG_1_N PF04588.8 KFX96863.1 - 1.3e-23 82.4 0.0 1.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1491 PF07372.7 KFX96863.1 - 0.014 15.2 1.9 0.029 14.2 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) CaMBD PF02888.11 KFX96863.1 - 0.14 11.9 4.5 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Calmodulin binding domain TUSC2 PF15000.1 KFX96863.1 - 0.25 11.4 7.9 0.49 10.4 0.1 3.1 1 1 2 3 3 3 0 Tumour suppressor candidate 2 DUF2514 PF10721.4 KFX96863.1 - 8.5 6.0 13.8 6.8 6.3 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) PALP PF00291.20 KFX96864.1 - 8.1e-75 251.8 0.7 1e-74 251.5 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KFX96864.1 - 6.8e-43 144.1 0.0 4.5e-22 77.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Peptidase_C12 PF01088.16 KFX96865.1 - 8.2e-54 182.0 0.0 1e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ZZ PF00569.12 KFX96866.1 - 1.3 8.5 6.4 2.7 7.6 4.4 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type AA_permease PF00324.16 KFX96868.1 - 1.6e-135 452.1 49.7 2e-135 451.8 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX96868.1 - 3.5e-34 118.0 54.9 4.6e-34 117.6 38.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF106 PF01956.11 KFX96882.1 - 4.3e-30 104.4 0.4 5.1e-30 104.2 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 PS_pyruv_trans PF04230.8 KFX96882.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase SPC25 PF06703.6 KFX96883.1 - 1.3e-32 112.6 0.0 1.5e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RRM_6 PF14259.1 KFX96888.1 - 1.2e-10 41.2 0.1 2.1e-09 37.1 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX96888.1 - 3.3e-09 36.2 0.6 0.0025 17.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX96888.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ino80_Iec3 PF14612.1 KFX96889.1 - 9.1e-53 179.6 0.3 1.3e-52 179.2 0.2 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.15 KFX96890.1 - 4.3e-72 242.9 0.0 5.3e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 KFX96890.1 - 0.077 13.0 0.5 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) GFA PF04828.9 KFX96893.1 - 5.6e-09 35.8 0.2 8.9e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Prim_Zn_Ribbon PF08273.7 KFX96893.1 - 2.1 8.4 4.7 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Patatin PF01734.17 KFX96894.1 - 8.4e-24 84.6 0.0 1.7e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 KFX96894.1 - 2e-15 56.4 0.0 4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 KFX96894.1 - 8.8e-11 41.3 0.1 4e-10 39.2 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX96894.1 - 5.2e-08 32.7 0.1 1.7e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_16 PF13191.1 KFX96894.1 - 1e-05 25.6 0.0 7.2e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFX96894.1 - 0.00045 20.3 0.0 0.0031 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.1 KFX96894.1 - 0.031 14.0 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DEP PF00610.16 KFX96894.1 - 0.04 13.6 0.3 0.26 11.0 0.0 2.5 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TPR_1 PF00515.23 KFX96894.1 - 0.043 13.4 0.3 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFX96894.1 - 0.093 12.3 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 KFX96894.1 - 0.096 13.3 0.0 0.55 10.9 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP30_Sin3_bdg PF13867.1 KFX96894.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 TPR_2 PF07719.12 KFX96894.1 - 0.18 11.8 2.1 0.43 10.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 KFX96897.1 - 1.3e-59 201.9 0.0 1.6e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.18 KFX96899.1 - 4.7e-27 94.5 14.4 5.6e-27 94.3 10.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain FtsX PF02687.16 KFX96899.1 - 0.23 11.2 0.1 0.23 11.2 0.0 2.8 2 1 0 2 2 2 0 FtsX-like permease family MpPF26 PF07666.6 KFX96899.1 - 0.27 11.1 7.5 0.46 10.3 3.4 2.4 2 1 0 2 2 2 0 M penetrans paralogue family 26 Defensin_big PF14862.1 KFX96899.1 - 0.78 9.8 2.7 8.8 6.4 1.9 2.2 1 1 0 1 1 1 0 Big defensin PNGaseA PF12222.3 KFX96901.1 - 6.2e-141 470.1 0.2 7.8e-141 469.8 0.1 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A ADH_N PF08240.7 KFX96902.1 - 6.2e-22 77.4 0.1 1.3e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX96902.1 - 9.4e-17 60.7 0.0 1.7e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX96902.1 - 0.0031 16.6 0.1 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX96902.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cwf_Cwc_15 PF04889.7 KFX96904.1 - 2.7e-47 161.5 11.2 2.9e-47 161.4 7.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 KFX96904.1 - 0.0077 16.3 6.3 0.0086 16.1 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) OmpH PF03938.9 KFX96904.1 - 1.5 8.7 5.4 1.8 8.4 3.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_polI_A34 PF08208.6 KFX96904.1 - 1.5 8.4 7.3 1.7 8.2 5.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3043 PF11241.3 KFX96904.1 - 2.5 7.6 6.6 3.3 7.2 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Cupin_2 PF07883.6 KFX96905.1 - 8.8e-07 28.3 0.1 1.2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KFX96905.1 - 0.073 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_3 PF01494.14 KFX96906.1 - 1.5e-28 99.9 0.2 2.1e-27 96.1 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX96906.1 - 1.1e-08 34.4 0.6 0.00064 18.7 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFX96906.1 - 2.2e-06 27.0 0.9 0.022 13.8 0.1 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KFX96906.1 - 2.3e-05 24.5 0.0 6.2e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX96906.1 - 4.1e-05 23.5 1.1 0.00012 21.9 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX96906.1 - 0.00011 21.3 0.6 0.04 12.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 KFX96906.1 - 0.00039 18.9 0.3 0.029 12.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFX96906.1 - 0.00041 19.5 0.3 0.0012 18.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KFX96906.1 - 0.001 19.4 1.7 0.017 15.4 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX96906.1 - 0.0059 16.4 0.4 0.015 15.1 0.1 1.7 2 0 0 2 2 2 1 ThiF family Pyr_redox_2 PF07992.9 KFX96906.1 - 0.007 16.2 0.6 0.016 15.0 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFX96906.1 - 0.0091 15.5 0.2 0.023 14.2 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KFX96906.1 - 0.012 15.4 1.2 5.7 6.6 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFX96906.1 - 0.017 13.9 1.0 0.028 13.2 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 KFX96906.1 - 0.018 15.0 0.0 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 KFX96906.1 - 0.019 13.5 0.1 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 KFX96906.1 - 0.098 12.0 0.3 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KFX96906.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 KFX96906.1 - 0.13 11.3 0.2 0.4 9.7 0.1 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KFX96907.1 - 2.2e-10 39.8 0.1 3.8e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96907.1 - 1.3e-09 37.7 8.5 2.7e-09 36.7 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 KFX96908.1 - 1.7e-16 61.2 0.0 4.3e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX96908.1 - 1e-12 47.6 0.0 2.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX96908.1 - 5.8e-07 29.2 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFX96908.1 - 1.8e-05 24.8 1.3 2.1e-05 24.6 0.3 1.6 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX96908.1 - 2e-05 24.8 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX96908.1 - 4.3e-05 23.4 0.3 9.5e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KFX96908.1 - 0.0048 15.8 0.0 0.0091 14.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KFX96908.1 - 0.026 14.4 0.3 0.66 9.8 0.1 2.4 3 0 0 3 3 3 0 short chain dehydrogenase NmrA PF05368.8 KFX96908.1 - 0.031 13.5 0.1 0.067 12.4 0.1 1.6 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 KFX96908.1 - 0.041 12.9 0.5 0.16 11.0 0.3 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldedh PF00171.17 KFX96909.1 - 2.8e-81 273.1 0.0 3.4e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.3 KFX96910.1 - 4.7e-05 22.1 2.1 0.00028 19.6 1.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KFX96911.1 - 1.6e-15 57.4 0.1 2.8e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX96911.1 - 5.3e-09 35.9 1.4 6e-09 35.8 0.1 1.6 2 0 0 2 2 2 1 KR domain MFS_1 PF07690.11 KFX96912.1 - 1.9e-09 36.7 40.1 1.1e-05 24.2 2.9 4.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX96912.1 - 0.0013 17.0 8.1 0.0013 17.0 5.6 2.7 3 1 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 KFX96912.1 - 0.53 10.1 3.2 1.4 8.7 0.1 2.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Methyltransf_2 PF00891.13 KFX96913.1 - 3.9e-29 101.5 0.0 1.1e-28 100.1 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase FeoC PF09012.5 KFX96913.1 - 0.0039 16.8 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator MarR_2 PF12802.2 KFX96913.1 - 0.0099 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 KFX96913.1 - 0.037 14.3 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 KFX96913.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rotamase_3 PF13616.1 KFX96914.1 - 8.3e-15 55.0 0.1 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KFX96914.1 - 1.4e-14 54.6 0.0 2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KFX96914.1 - 0.0014 19.2 1.6 0.0036 17.9 0.0 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain WW PF00397.21 KFX96921.1 - 1.8e-07 30.8 0.3 3.9e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 WW domain Ank_5 PF13857.1 KFX96922.1 - 4.8e-20 71.1 0.1 2.8e-11 43.2 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) VPS9 PF02204.13 KFX96922.1 - 9.8e-15 54.4 0.0 2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KFX96922.1 - 2.1e-14 53.6 0.0 8.5e-06 26.0 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFX96922.1 - 2.5e-11 42.6 0.2 0.32 11.3 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KFX96922.1 - 2.7e-11 43.6 0.2 0.0011 19.4 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KFX96922.1 - 1.4e-08 34.0 0.7 0.0036 17.0 0.0 5.5 5 1 0 5 5 5 1 Ankyrin repeat PX PF00787.19 KFX96922.1 - 0.004 16.9 0.2 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 PX domain PGM_PMM_I PF02878.11 KFX96923.1 - 1.9e-31 108.3 0.3 3.9e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RNase_T PF00929.19 KFX96923.1 - 2.8e-26 92.7 0.1 6.6e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 Exonuclease PGM_PMM_III PF02880.11 KFX96923.1 - 1.2e-23 83.3 0.0 2.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KFX96923.1 - 1.4e-16 60.6 1.0 2.5e-16 59.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFX96923.1 - 4e-11 42.7 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Atg31 PF09795.4 KFX96923.1 - 0.032 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 31 GFO_IDH_MocA PF01408.17 KFX96924.1 - 7.5e-10 39.3 0.0 1.7e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX96924.1 - 3.3e-05 23.6 0.0 7.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Dus PF01207.12 KFX96925.1 - 1.6e-39 135.6 0.0 7.9e-29 100.4 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Kelch_4 PF13418.1 KFX96926.1 - 1e-40 137.2 19.7 3e-10 39.6 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KFX96926.1 - 1.9e-40 136.1 15.3 2.1e-07 30.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFX96926.1 - 3.5e-40 135.2 22.9 5.6e-09 35.9 0.0 7.5 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFX96926.1 - 2.7e-38 129.3 14.1 8.8e-07 28.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFX96926.1 - 6e-32 108.4 17.3 8.7e-07 28.8 0.1 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFX96926.1 - 3.9e-31 105.6 13.3 2.3e-06 27.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif HIG_1_N PF04588.8 KFX96927.1 - 3.7e-07 29.7 1.1 3.7e-07 29.7 0.8 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region zf-C2H2_4 PF13894.1 KFX96928.1 - 5.9e-06 26.2 13.4 0.045 14.0 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX96928.1 - 1.5e-05 25.0 5.8 0.0016 18.5 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFX96928.1 - 0.0011 19.0 3.4 0.031 14.4 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX96928.1 - 0.016 15.0 0.5 0.016 15.0 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX96928.1 - 0.02 15.2 19.2 0.076 13.3 1.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Plasmodium_Vir PF05795.6 KFX96928.1 - 0.022 13.9 0.1 0.049 12.8 0.1 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Tetraspannin PF00335.15 KFX96928.1 - 0.19 10.9 0.3 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF3138 PF11336.3 KFX96931.1 - 0.016 13.4 0.7 0.044 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) FlxA PF14282.1 KFX96931.1 - 0.025 14.5 0.1 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 FlxA-like protein ADIP PF11559.3 KFX96931.1 - 0.082 12.8 3.2 0.14 12.0 2.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Glutaredoxin PF00462.19 KFX96933.1 - 1.8e-12 47.0 0.0 4.8e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin DUF2427 PF10348.4 KFX96940.1 - 2.1e-06 27.2 2.3 4.3e-06 26.2 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DOMON PF03351.12 KFX96940.1 - 7.4e-06 25.9 0.1 1.3e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 KFX96940.1 - 7.2e-05 22.6 9.6 7.2e-05 22.6 6.7 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 ABC2_membrane_5 PF13346.1 KFX96940.1 - 1.4 8.1 4.2 0.29 10.3 0.4 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Pkinase PF00069.20 KFX96941.1 - 5e-65 219.2 0.0 6.3e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96941.1 - 5.5e-30 104.3 0.0 7.4e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96941.1 - 2.8e-05 23.2 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CRF1 PF10380.4 KFX96943.1 - 0.0019 18.5 0.5 0.0057 16.9 0.0 2.2 2 0 0 2 2 2 1 Transcription factor CRF1 Myb_DNA-bind_6 PF13921.1 KFX96945.1 - 6.1e-15 55.0 1.4 1.6e-14 53.7 1.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX96945.1 - 0.0013 18.7 0.7 0.0026 17.7 0.5 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dabb PF07876.7 KFX96954.1 - 1.1e-21 77.0 0.1 1.3e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Laminin_EGF PF00053.19 KFX96955.1 - 0.086 12.7 6.2 0.18 11.7 4.3 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) CFEM PF05730.6 KFX96955.1 - 0.39 10.5 10.9 0.63 9.8 7.5 1.3 1 0 0 1 1 1 0 CFEM domain RAP1 PF07218.6 KFX96955.1 - 5 5.0 15.3 5.1 5.0 10.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HATPase_c_3 PF13589.1 KFX96956.1 - 1.6e-15 56.9 0.0 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KFX96956.1 - 3.7e-05 23.3 0.0 0.00044 19.8 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KFX96956.1 - 0.00098 18.8 0.0 0.0031 17.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FNIP_N PF14636.1 KFX96974.1 - 0.0089 16.4 0.0 0.0089 16.4 0.0 3.3 4 0 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KFX96974.1 - 0.035 13.6 0.1 0.29 10.6 0.0 2.3 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Complex1_LYR_2 PF13233.1 KFX96979.1 - 0.00056 20.3 0.3 0.00076 19.9 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX96979.1 - 0.0048 16.6 0.1 0.012 15.4 0.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.3 KFX96979.1 - 0.0088 15.4 1.2 0.13 11.6 0.1 2.0 1 1 1 2 2 2 1 R.HinP1I restriction endonuclease Complex1_LYR_1 PF13232.1 KFX96979.1 - 0.022 14.9 0.4 0.034 14.3 0.3 1.5 1 0 0 1 1 1 0 Complex1_LYR-like RNA_pol_L_2 PF13656.1 KFX96980.1 - 1.3e-31 107.7 0.0 2e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFX96980.1 - 3.3e-11 42.1 0.0 4.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain G10 PF01125.12 KFX96989.1 - 8.7e-12 44.8 0.0 1.2e-11 44.3 0.0 1.3 1 1 0 1 1 1 1 G10 protein MARVEL PF01284.18 KFX96991.1 - 1e-15 57.7 13.2 1.2e-15 57.5 9.1 1.0 1 0 0 1 1 1 1 Membrane-associating domain Mpv17_PMP22 PF04117.7 KFX96993.1 - 1.7e-15 56.4 0.2 1.7e-15 56.4 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family NQR2_RnfD_RnfE PF03116.10 KFX96993.1 - 0.024 13.8 0.3 0.032 13.4 0.2 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Glyco_transf_22 PF03901.12 KFX96994.1 - 3.2e-46 158.1 3.4 3.7e-46 157.9 2.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_17 PF00332.13 KFX96996.1 - 3.3e-05 23.0 0.2 5.9e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Abhydrolase_6 PF12697.2 KFX96997.1 - 3.5e-17 63.0 0.1 1.8e-16 60.7 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX96997.1 - 1.9e-05 24.4 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX96997.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase PF00069.20 KFX96998.1 - 1.2e-59 201.6 0.0 1.4e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96998.1 - 2.7e-36 124.9 0.0 4.3e-36 124.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96998.1 - 2.7e-08 33.1 0.0 3.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFX96998.1 - 0.094 11.5 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DEAD PF00270.24 KFX96999.1 - 3.3e-40 137.3 0.0 3.7e-39 133.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX96999.1 - 6.2e-27 93.2 0.2 8.1e-26 89.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFX96999.1 - 1.8e-05 23.6 0.0 3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFX96999.1 - 0.052 13.3 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2759 PF10958.3 KFX97000.1 - 0.3 10.6 1.4 23 4.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) SRF-TF PF00319.13 KFX97004.1 - 3.5e-05 22.9 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AAA PF00004.24 KFX97005.1 - 1.9e-16 60.4 0.0 3.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFX97005.1 - 3e-05 23.7 0.0 5.8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFX97005.1 - 8.4e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX97005.1 - 9.8e-05 22.5 0.3 0.0032 17.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX97005.1 - 0.00027 21.0 0.0 0.00075 19.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFX97005.1 - 0.00068 20.4 0.0 0.002 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX97005.1 - 0.0025 18.1 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX97005.1 - 0.003 16.6 0.0 0.0072 15.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFX97005.1 - 0.0034 17.2 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFX97005.1 - 0.013 14.7 0.4 0.026 13.7 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 KFX97005.1 - 0.015 14.9 1.0 0.48 10.0 0.1 2.6 1 1 1 2 2 2 0 Bacterial dnaA protein Zot PF05707.7 KFX97005.1 - 0.022 14.2 0.1 0.43 10.0 0.0 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 KFX97005.1 - 0.025 14.7 0.0 0.069 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KFX97005.1 - 0.025 14.2 0.1 0.37 10.4 0.0 2.4 1 1 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 KFX97005.1 - 0.032 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX97005.1 - 0.066 12.6 0.1 0.24 10.7 0.1 1.7 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFX97005.1 - 0.095 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KFX97005.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KFX97008.1 - 7.5e-12 44.9 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97008.1 - 9e-09 34.7 0.0 1.5e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase AAA PF00004.24 KFX97009.1 - 4.6e-18 65.7 0.0 1.1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX97009.1 - 2.3e-05 24.5 0.1 0.00053 20.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KFX97009.1 - 0.00018 21.2 0.0 0.00051 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX97009.1 - 0.00036 20.5 0.1 0.0022 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 KFX97009.1 - 0.00036 20.1 0.0 0.0048 16.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFX97009.1 - 0.00078 20.2 0.2 0.0044 17.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFX97009.1 - 0.002 18.0 0.1 0.82 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFX97009.1 - 0.0046 16.0 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KFX97009.1 - 0.005 17.1 0.5 0.023 14.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFX97009.1 - 0.014 15.2 0.0 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KFX97009.1 - 0.04 13.0 0.1 0.079 12.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFX97009.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KFX97009.1 - 0.059 12.7 0.2 0.37 10.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KFX97009.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KFX97009.1 - 0.13 11.6 0.1 2.1 7.7 0.0 2.5 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) CENP-B_N PF04218.8 KFX97012.1 - 7.3e-07 28.5 0.1 2.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KFX97012.1 - 0.00099 18.6 0.2 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.11 KFX97012.1 - 0.0035 17.1 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.11 KFX97012.1 - 0.004 16.4 0.0 0.0092 15.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.1 KFX97012.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 KFX97012.1 - 0.0071 16.0 0.0 0.063 12.9 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.1 KFX97012.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 KFX97012.1 - 0.058 13.0 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.1 KFX97012.1 - 0.069 12.8 0.2 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain SusD-like PF12741.2 KFX97012.1 - 0.11 11.0 0.3 0.33 9.4 0.1 1.7 2 0 0 2 2 2 0 Susd and RagB outer membrane lipoprotein Acetyltransf_1 PF00583.19 KFX97014.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX97014.1 - 5.7e-07 29.6 0.0 9.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX97014.1 - 2.5e-06 27.5 0.0 7.2e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX97014.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX97014.1 - 0.052 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 KFX97014.1 - 0.059 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Myb_DNA-bind_6 PF13921.1 KFX97016.1 - 0.005 16.9 0.4 0.067 13.3 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Abhydrolase_3 PF07859.8 KFX97017.1 - 3.5e-50 170.5 0.0 5.1e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX97017.1 - 1.1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFX97017.1 - 4.7e-05 23.1 0.0 9.6e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX97017.1 - 0.00013 20.7 0.0 0.00021 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Epimerase PF01370.16 KFX97017.1 - 0.0005 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX97017.1 - 0.0082 15.0 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KFX97017.1 - 0.021 14.8 0.0 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Lipase_3 PF01764.20 KFX97017.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.11 KFX97020.1 - 3.1e-31 108.3 37.5 3.1e-31 108.3 26.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SBP_bac_11 PF13531.1 KFX97020.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF4066 PF13278.1 KFX97021.1 - 3.6e-23 81.6 0.0 4.9e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX97021.1 - 6.8e-11 41.8 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family EHN PF06441.7 KFX97022.1 - 3e-26 91.5 0.2 4.5e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFX97022.1 - 7.2e-09 35.8 0.0 1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX97022.1 - 8.4e-07 28.7 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.13 KFX97023.1 - 0.011 15.6 9.9 0.019 14.8 6.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 KFX97024.1 - 4.7e-82 275.1 0.1 8.5e-82 274.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFX97024.1 - 5e-44 148.8 3.0 1.5e-43 147.2 2.1 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KFX97024.1 - 8.2e-36 122.8 0.5 8.2e-36 122.8 0.3 4.8 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 KFX97024.1 - 6.4e-15 54.7 0.0 2.3e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX97024.1 - 1.4e-09 38.0 0.2 1.9e-08 34.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX97024.1 - 6.9e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 KFX97024.1 - 0.0035 17.3 0.0 0.067 13.2 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 KFX97024.1 - 0.027 13.8 0.1 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KFX97024.1 - 0.044 13.6 0.1 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFX97024.1 - 0.11 12.6 1.3 0.92 9.6 0.1 3.2 2 1 0 2 2 2 0 AAA domain DUF4588 PF15251.1 KFX97025.1 - 0.017 15.0 6.4 0.046 13.6 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) ECR1_N PF14382.1 KFX97026.1 - 8.6e-11 40.9 0.0 2.4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 KFX97026.1 - 0.0085 16.1 0.4 0.16 12.0 0.0 3.1 4 0 0 4 4 4 1 S1 RNA binding domain EXOSC1 PF10447.4 KFX97026.1 - 0.079 12.9 0.4 1.3 9.0 0.0 2.8 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 DUF4536 PF15055.1 KFX97027.1 - 0.027 14.5 1.1 0.069 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.16 KFX97028.1 - 3e-57 193.7 0.0 4.9e-57 193.0 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFX97028.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Uds1 PF15456.1 KFX97029.1 - 1.4e-34 118.6 4.9 1.4e-34 118.6 3.4 1.8 2 0 0 2 2 2 1 Up-regulated During Septation Wbp11 PF09429.5 KFX97029.1 - 0.02 14.8 0.1 0.061 13.3 0.1 1.7 1 0 0 1 1 1 0 WW domain binding protein 11 Peptidase_M1 PF01433.15 KFX97031.1 - 5.6e-69 233.0 0.0 7.2e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFX97031.1 - 3.3e-42 143.4 0.0 5.7e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFX97031.1 - 1.2e-17 64.1 0.4 2e-17 63.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KFX97031.1 - 0.11 12.5 2.3 0.52 10.3 1.6 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M20 PF01546.23 KFX97032.1 - 4.4e-32 111.1 0.0 7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX97032.1 - 2.3e-15 56.2 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF761 PF05553.6 KFX97032.1 - 0.093 12.0 0.2 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Cotton fibre expressed protein PPR_2 PF13041.1 KFX97033.1 - 1e-10 41.4 0.0 0.00045 20.1 0.0 3.8 3 1 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KFX97033.1 - 7.9e-06 25.7 0.3 0.72 10.2 0.0 4.7 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 KFX97033.1 - 0.0026 17.6 0.8 10 6.3 0.0 3.9 4 0 0 4 4 4 2 PPR repeat RNA_pol_Rpb1_5 PF04998.12 KFX97034.1 - 3.2e-89 298.8 0.1 5.2e-89 298.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KFX97034.1 - 1.2e-87 294.3 0.0 1.7e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KFX97034.1 - 1.6e-65 220.1 0.0 3.5e-65 219.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFX97034.1 - 2.9e-39 134.3 0.0 6.7e-39 133.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KFX97034.1 - 3.4e-29 100.7 0.2 1.2e-28 99.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Phlebovirus_NSM PF07246.6 KFX97035.1 - 0.039 13.1 0.5 0.043 12.9 0.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4232 PF14016.1 KFX97035.1 - 0.1 12.2 1.3 0.14 11.8 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) IncA PF04156.9 KFX97036.1 - 0.47 10.0 2.4 1.1 8.8 1.6 1.5 1 1 0 1 1 1 0 IncA protein AA_permease_2 PF13520.1 KFX97037.1 - 9e-40 136.4 50.7 1.2e-39 136.0 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX97037.1 - 2.4e-14 52.5 42.4 3.3e-14 52.1 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_9 PF13527.1 KFX97038.1 - 4e-05 23.4 0.0 0.26 11.1 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX97038.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX97038.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX97038.1 - 0.0059 16.7 0.0 0.021 14.9 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 KFX97040.1 - 5.6e-58 196.4 45.9 7.1e-58 196.1 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX97040.1 - 2.6e-32 111.8 36.3 3.3e-32 111.4 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KFX97041.1 - 1.8e-09 36.8 24.1 1.8e-09 36.8 16.7 3.7 2 2 1 3 3 3 1 Major Facilitator Superfamily SPW PF03779.9 KFX97041.1 - 0.041 13.2 3.7 0.043 13.2 0.3 2.8 3 0 0 3 3 3 0 SPW repeat PP_M1 PF03012.9 KFX97041.1 - 0.32 10.3 0.1 0.48 9.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein FAD_binding_3 PF01494.14 KFX97043.1 - 3.3e-15 56.0 0.5 2.1e-14 53.3 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX97043.1 - 1.2e-07 31.0 0.4 3e-05 23.1 0.1 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX97043.1 - 6.7e-07 29.6 0.2 0.00011 22.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX97043.1 - 0.0051 16.7 0.2 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX97043.1 - 0.024 14.4 0.1 0.066 13.0 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX97043.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 KFX97044.1 - 5.7e-18 64.7 0.1 9.1e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97044.1 - 1e-08 34.9 10.5 1.9e-08 34.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 KFX97045.1 - 4.6e-62 209.6 0.7 8e-62 208.8 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 KFX97046.1 - 1.3e-127 426.1 37.3 1.5e-127 425.9 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97046.1 - 6.8e-19 67.7 44.3 8.8e-16 57.5 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Erg28 PF03694.8 KFX97053.1 - 7.9e-19 67.7 0.0 9.3e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Erg28 like protein WSC PF01822.14 KFX97054.1 - 6.4e-09 35.6 5.3 6.4e-09 35.6 3.6 2.4 2 1 0 2 2 2 1 WSC domain NYN PF01936.13 KFX97055.1 - 0.00086 19.6 0.0 0.0056 16.9 0.0 2.3 1 1 0 1 1 1 1 NYN domain Rpn3_C PF08375.6 KFX97056.1 - 3.8e-24 84.8 1.5 9.7e-24 83.5 1.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KFX97056.1 - 1.7e-19 70.0 0.4 4.3e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KFX97056.1 - 0.0027 17.4 0.2 0.013 15.3 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat MOZ_SAS PF01853.13 KFX97057.1 - 2.8e-61 206.0 0.0 4.1e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family adh_short PF00106.20 KFX97059.1 - 1.9e-18 66.9 0.2 3e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX97059.1 - 3.3e-05 23.6 0.3 5.2e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFX97059.1 - 0.043 13.9 0.2 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KFX97059.1 - 0.082 12.7 2.4 0.11 12.2 0.7 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_16 PF13191.1 KFX97060.1 - 3.6e-06 27.0 0.1 0.00016 21.7 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KFX97060.1 - 3.1e-05 23.7 0.1 5.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KFX97060.1 - 0.0024 18.0 0.1 0.0094 16.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFX97060.1 - 0.0055 16.1 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KFX97060.1 - 0.0065 15.9 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 KFX97060.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KFX97060.1 - 0.16 12.4 0.2 1.3 9.5 0.2 2.4 1 1 0 1 1 1 0 Miro-like protein Myb_DNA-bind_6 PF13921.1 KFX97061.1 - 9.3e-19 67.2 6.8 2.9e-13 49.6 0.6 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX97061.1 - 6.7e-17 61.2 6.2 3.2e-09 36.6 0.7 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KFX97061.1 - 0.0048 17.0 8.6 0.48 10.6 0.2 3.7 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 KFX97061.1 - 0.014 15.4 7.5 0.06 13.4 0.6 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Fer4 PF00037.22 KFX97062.1 - 1.4e-13 49.7 16.5 5.4e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KFX97062.1 - 3.4e-12 46.5 10.5 5.8e-12 45.8 7.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFX97062.1 - 1.7e-09 37.3 22.0 5.5e-08 32.4 8.4 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFX97062.1 - 2.8e-09 37.1 11.0 5.2e-09 36.2 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFX97062.1 - 3.1e-09 37.4 8.2 0.00019 22.1 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 KFX97062.1 - 9.9e-09 34.9 31.9 1.4e-05 24.8 8.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFX97062.1 - 5.2e-08 32.7 19.7 1.5e-05 24.9 7.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFX97062.1 - 1.3e-07 31.1 14.7 0.00044 19.9 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KFX97062.1 - 2.5e-07 30.2 17.1 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KFX97062.1 - 4.9e-06 26.4 12.7 0.00059 19.9 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KFX97062.1 - 6.2e-06 26.4 10.1 0.0006 20.1 7.5 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFX97062.1 - 3.5e-05 24.1 9.4 0.013 15.8 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KFX97062.1 - 0.0098 16.2 15.6 0.3 11.4 3.2 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KFX97062.1 - 0.018 15.5 13.5 0.29 11.7 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KFX97062.1 - 0.067 13.7 16.9 0.16 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KFX97062.1 - 0.12 12.5 4.8 0.14 12.3 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 KFX97063.1 - 1.3e-11 44.6 0.1 1.6e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KFX97063.1 - 2e-07 30.9 0.1 2.7e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 KFX97063.1 - 0.021 14.9 0.1 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) GPP34 PF05719.6 KFX97064.1 - 3.1e-64 216.8 0.1 4e-64 216.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GRAM PF02893.15 KFX97067.1 - 2.7e-27 94.0 0.6 1.1e-15 56.8 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KFX97067.1 - 1.5e-24 86.3 0.0 2.9e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KFX97067.1 - 1.3e-12 47.8 0.0 7.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 PH domain WD40 PF00400.27 KFX97067.1 - 1.8e-10 40.2 8.4 0.0029 17.4 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PH_8 PF15409.1 KFX97067.1 - 0.00075 19.5 0.1 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KFX97067.1 - 0.00081 19.6 3.9 0.0042 17.3 0.3 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 KFX97067.1 - 0.0032 17.4 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 KFX97067.1 - 0.029 12.9 0.0 0.049 12.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PPR_2 PF13041.1 KFX97068.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family SNF2_N PF00176.18 KFX97069.1 - 3.1e-66 223.2 0.0 4.2e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KFX97069.1 - 1.1e-61 208.0 0.2 2e-61 207.2 0.1 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 KFX97069.1 - 6.5e-13 48.3 0.0 4.2e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX97069.1 - 9.3e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFX97069.1 - 0.00016 20.6 0.0 0.00045 19.1 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KFX97069.1 - 0.074 13.1 0.2 0.96 9.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KFX97070.1 - 9.6e-49 163.0 6.5 3.1e-19 68.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Thg1C PF14413.1 KFX97074.1 - 1.4e-50 169.9 0.2 1.9e-50 169.6 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KFX97074.1 - 3.5e-45 152.9 0.0 5e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase E1-E2_ATPase PF00122.15 KFX97074.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase AlaDh_PNT_N PF05222.10 KFX97075.1 - 5.3e-28 97.7 0.0 8.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFX97075.1 - 1.5e-18 66.9 0.1 2.1e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KFX97080.1 - 6.5e-26 91.6 0.0 1.8e-25 90.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX97080.1 - 1.3e-11 44.0 0.0 4.9e-09 35.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX97080.1 - 5.3e-10 39.5 0.0 5.9e-09 36.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX97080.1 - 5.8e-09 34.6 0.0 1.3e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KFX97080.1 - 4.7e-05 23.1 0.1 0.12 12.1 0.0 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KFX97080.1 - 0.00024 20.1 0.0 0.34 9.7 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KFX97080.1 - 0.0013 17.9 0.1 0.0055 15.8 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KFX97080.1 - 0.0022 17.9 0.0 0.0088 16.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX97080.1 - 0.044 12.2 0.1 1.7 7.0 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 KFX97080.1 - 0.13 11.0 0.1 2.7 6.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KFX97080.1 - 0.19 10.6 0.1 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Methyltransf_25 PF13649.1 KFX97081.1 - 2.3e-13 50.3 0.0 5.6e-13 49.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97081.1 - 1.1e-12 48.4 0.0 2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97081.1 - 5.2e-12 46.0 0.0 8.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97081.1 - 2.1e-11 43.6 0.0 2.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97081.1 - 1.6e-10 40.9 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97081.1 - 5e-09 36.2 0.0 8.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97081.1 - 3.5e-08 33.8 0.0 7.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX97081.1 - 4.2e-06 26.2 0.0 6.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KFX97081.1 - 3.5e-05 23.0 0.0 5.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 KFX97081.1 - 9.2e-05 21.6 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Spermine_synth PF01564.12 KFX97081.1 - 0.0005 19.0 0.0 0.0012 17.8 0.0 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_16 PF10294.4 KFX97081.1 - 0.005 16.3 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_20 PF12147.3 KFX97081.1 - 0.014 14.2 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 KFX97081.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ApbA PF02558.11 KFX97081.1 - 0.023 14.1 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_15 PF09445.5 KFX97081.1 - 0.027 14.0 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NodS PF05401.6 KFX97081.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) 3HCDH_N PF02737.13 KFX97081.1 - 0.055 13.1 0.1 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPMT PF05724.6 KFX97081.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) UDPG_MGDP_dh_N PF03721.9 KFX97081.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cellulase PF00150.13 KFX97082.1 - 4.4e-52 177.0 1.7 5.5e-52 176.7 1.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFX97082.1 - 5e-12 45.2 15.4 5e-12 45.2 10.7 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Acetyltransf_1 PF00583.19 KFX97083.1 - 1.2e-07 31.5 0.2 3.9e-07 30.0 0.0 1.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX97083.1 - 0.0003 20.8 0.1 0.0008 19.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX97083.1 - 0.00089 19.3 0.1 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX97083.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFX97083.1 - 0.014 15.3 0.0 0.026 14.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_kinase PF01513.16 KFX97084.1 - 3e-47 160.7 0.0 4.7e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF4138 PF13595.1 KFX97084.1 - 0.22 10.4 0.1 0.63 8.9 0.0 1.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4138) Acyltransferase PF01553.16 KFX97085.1 - 6.9e-24 83.7 0.0 1.2e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Cyclin_N PF00134.18 KFX97085.1 - 7.9e-10 38.3 0.1 1.5e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KFX97085.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat CFEM PF05730.6 KFX97086.1 - 8.2e-10 38.3 10.1 1.6e-09 37.4 7.0 1.5 1 0 0 1 1 1 1 CFEM domain ABC_tran PF00005.22 KFX97087.1 - 5e-49 166.1 0.0 2.4e-28 99.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX97087.1 - 2.7e-32 112.2 29.0 1.2e-20 74.1 8.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX97087.1 - 9.8e-14 51.9 5.0 0.0022 18.0 0.0 4.9 4 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KFX97087.1 - 7.1e-10 38.4 5.0 0.066 12.4 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFX97087.1 - 4.9e-09 36.4 0.3 0.0023 17.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFX97087.1 - 1.2e-08 34.3 0.5 0.00071 19.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KFX97087.1 - 1.3e-06 27.9 0.2 0.0011 18.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX97087.1 - 2.2e-06 27.6 0.1 0.13 12.2 0.1 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFX97087.1 - 1.5e-05 25.4 1.1 0.13 12.7 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KFX97087.1 - 2e-05 23.8 1.0 0.073 12.2 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX97087.1 - 6.2e-05 23.1 2.2 0.067 13.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX97087.1 - 0.00014 21.3 1.3 0.13 11.7 0.0 2.6 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KFX97087.1 - 0.00022 20.7 3.4 0.066 12.6 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 KFX97087.1 - 0.0003 21.2 0.4 0.11 12.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX97087.1 - 0.00033 19.6 0.5 0.016 14.1 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 KFX97087.1 - 0.00035 20.3 3.0 0.096 12.3 0.6 2.4 2 0 0 2 2 2 2 NTPase MobB PF03205.9 KFX97087.1 - 0.00074 19.2 1.1 0.28 10.8 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KFX97087.1 - 0.0017 18.2 1.9 0.036 13.8 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 cobW PF02492.14 KFX97087.1 - 0.0025 17.2 1.9 0.12 11.8 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KFX97087.1 - 0.0038 16.0 0.9 0.97 8.1 0.1 2.2 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 KFX97087.1 - 0.0038 17.5 2.4 0.31 11.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KFX97087.1 - 0.0059 16.1 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KFX97087.1 - 0.0091 15.8 1.0 0.61 9.9 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFX97087.1 - 0.011 15.9 0.0 0.52 10.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KFX97087.1 - 0.011 15.6 4.0 0.041 13.7 0.1 2.4 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 KFX97087.1 - 0.012 14.7 0.7 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 KFX97087.1 - 0.016 14.9 0.0 2.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase DUF815 PF05673.8 KFX97087.1 - 0.017 14.0 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 KFX97087.1 - 0.022 13.7 1.0 3 6.7 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_17 PF13207.1 KFX97087.1 - 0.024 15.4 7.9 0.42 11.4 0.4 3.0 2 1 0 3 3 2 0 AAA domain AAA_14 PF13173.1 KFX97087.1 - 0.026 14.4 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFX97087.1 - 0.028 14.5 0.4 11 6.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.12 KFX97087.1 - 0.032 13.7 0.8 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 KFX97087.1 - 0.034 12.7 1.1 3.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 KFX97087.1 - 0.036 12.9 1.1 4.2 6.1 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 KFX97087.1 - 0.042 13.4 1.1 5.2 6.6 0.2 2.6 2 0 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.9 KFX97087.1 - 0.068 12.1 0.0 4.3 6.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.9 KFX97087.1 - 0.15 11.7 0.3 4.9 6.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFX97087.1 - 0.16 11.4 0.3 6.5 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFX97087.1 - 0.17 11.6 0.9 0.51 10.1 0.2 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_15 PF13175.1 KFX97087.1 - 0.27 10.2 0.3 12 4.7 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain RNA12 PF10443.4 KFX97087.1 - 0.28 9.6 0.3 0.52 8.7 0.0 1.4 2 0 0 2 2 1 0 RNA12 protein Viral_helicase1 PF01443.13 KFX97087.1 - 0.41 10.1 1.4 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 KFX97087.1 - 0.51 9.8 1.1 53 3.3 0.1 3.2 4 0 0 4 4 3 0 AAA domain PRK PF00485.13 KFX97087.1 - 0.7 9.4 3.6 0.49 9.9 0.2 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SNF2_N PF00176.18 KFX97088.1 - 7.6e-71 238.3 1.2 1.5e-70 237.3 0.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KFX97088.1 - 9.8e-53 177.9 22.0 9.8e-53 177.9 15.3 3.6 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 KFX97088.1 - 7.6e-16 57.7 0.0 2.6e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhyH PF05721.8 KFX97088.1 - 1.8e-06 28.1 0.5 9.2e-06 25.8 0.0 2.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) ABC_tran PF00005.22 KFX97089.1 - 1.2e-44 151.9 0.1 1.5e-21 77.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KFX97089.1 - 1.8e-21 75.7 7.6 2.1e-20 72.3 2.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KFX97089.1 - 2.7e-20 73.5 0.2 0.00068 19.6 0.1 4.2 3 1 1 4 4 4 4 AAA domain AAA_23 PF13476.1 KFX97089.1 - 1.4e-09 38.6 2.8 0.00084 19.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KFX97089.1 - 8.7e-09 34.9 0.1 0.0093 15.2 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX97089.1 - 1.7e-08 33.8 0.5 0.00051 19.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFX97089.1 - 1.3e-06 27.7 0.1 0.00092 18.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFX97089.1 - 5.4e-06 27.2 0.1 0.089 13.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KFX97089.1 - 1.5e-05 25.2 0.0 0.087 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFX97089.1 - 3.6e-05 24.2 0.0 0.1 13.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein RNA_helicase PF00910.17 KFX97089.1 - 0.0001 22.4 1.5 0.86 9.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.7 KFX97089.1 - 0.00018 21.2 0.3 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 KFX97089.1 - 0.0003 20.9 0.0 0.38 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX97089.1 - 0.00031 20.6 0.0 0.23 11.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KFX97089.1 - 0.00041 20.3 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KFX97089.1 - 0.00054 19.1 0.0 0.42 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KFX97089.1 - 0.00079 18.8 0.0 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX97089.1 - 0.00084 19.3 0.1 0.48 10.3 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFX97089.1 - 0.0014 18.5 0.0 0.39 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX97089.1 - 0.002 17.6 1.4 0.11 11.8 0.3 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_5 PF07728.9 KFX97089.1 - 0.002 17.8 0.1 0.59 9.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KFX97089.1 - 0.0022 18.1 0.0 0.96 9.6 0.0 3.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KFX97089.1 - 0.0058 16.5 0.6 0.61 10.0 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.6 KFX97089.1 - 0.01 15.3 0.1 4.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E Dynamin_N PF00350.18 KFX97089.1 - 0.015 15.1 0.3 6.4 6.5 0.0 3.2 3 0 0 3 3 3 0 Dynamin family MobB PF03205.9 KFX97089.1 - 0.016 14.8 0.3 0.17 11.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 KFX97089.1 - 0.017 14.0 0.3 3.6 6.4 0.0 2.9 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 KFX97089.1 - 0.019 13.8 0.0 1.8 7.3 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Arch_ATPase PF01637.13 KFX97089.1 - 0.02 14.6 0.0 8.4 6.0 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_14 PF13173.1 KFX97089.1 - 0.02 14.8 0.0 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Pepsin-I3 PF06394.8 KFX97089.1 - 0.023 14.3 0.3 0.29 10.8 0.0 2.6 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain DUF2813 PF11398.3 KFX97089.1 - 0.025 13.6 0.4 5.1 6.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) ArgK PF03308.11 KFX97089.1 - 0.051 12.3 0.1 5.3 5.7 0.0 2.7 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 KFX97089.1 - 0.081 12.4 3.6 0.87 9.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 KFX97089.1 - 0.09 11.4 0.5 15 4.1 0.0 2.9 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 KFX97089.1 - 0.17 11.4 1.0 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KFX97089.1 - 0.3 10.6 4.3 6.1 6.3 0.1 3.4 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 KFX97089.1 - 0.99 9.0 2.9 3.6 7.2 0.1 2.7 3 0 0 3 3 2 0 NTPase Zn_clus PF00172.13 KFX97090.1 - 2.3e-05 24.2 9.4 3.9e-05 23.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX97091.1 - 4.8e-42 143.9 42.5 4.8e-42 143.9 29.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97091.1 - 1.8e-11 43.3 15.9 1.8e-11 43.3 11.0 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2530 PF10745.4 KFX97091.1 - 2.9 7.9 14.2 1.5 8.8 0.8 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) DUF1129 PF06570.6 KFX97091.1 - 3.1 7.0 10.7 1.4 8.2 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Fungal_trans PF04082.13 KFX97092.1 - 2.4e-08 33.1 0.0 3.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97092.1 - 8.1e-06 25.6 2.6 1.8e-05 24.5 1.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX97093.1 - 9.7e-24 84.1 0.2 1.8e-23 83.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX97093.1 - 2.2e-10 40.6 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX97093.1 - 1.1e-09 38.2 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX97093.1 - 4.1e-06 26.3 0.0 1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97093.1 - 1.2e-05 25.4 0.0 4.9e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KFX97093.1 - 0.00028 20.1 0.0 0.00032 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KFX97093.1 - 0.0097 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 KFX97093.1 - 0.021 14.1 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family ETF_alpha PF00766.14 KFX97093.1 - 0.035 13.7 0.2 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Polysacc_synt_2 PF02719.10 KFX97093.1 - 0.066 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MUG113 PF13455.1 KFX97094.1 - 1.3e-32 112.0 1.3 2.2e-32 111.3 0.1 2.0 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KFX97094.1 - 2.3e-23 82.4 0.0 8.1e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 T5orf172 domain Radical_SAM PF04055.16 KFX97095.1 - 3.2e-15 56.6 0.0 8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KFX97095.1 - 5.7e-12 45.4 0.0 1.5e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Adap_comp_sub PF00928.16 KFX97096.1 - 3.6e-85 285.2 0.0 4.9e-85 284.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family CoA_binding PF02629.14 KFX97096.1 - 1.6e-25 89.4 1.1 1.6e-25 89.4 0.8 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFX97096.1 - 7.6e-23 80.8 0.1 1.4e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFX97096.1 - 8.2e-09 35.1 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KFX97096.1 - 0.0006 19.9 0.3 0.0021 18.1 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Clat_adaptor_s PF01217.15 KFX97096.1 - 0.0029 17.3 0.1 0.0066 16.1 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 KFX97096.1 - 0.075 12.9 0.2 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) GFO_IDH_MocA PF01408.17 KFX97097.1 - 4.1e-18 66.0 0.2 7.3e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX97097.1 - 0.00036 20.2 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KFX97097.1 - 0.011 16.0 0.1 0.028 14.7 0.1 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Gly_transf_sug PF04488.10 KFX97114.1 - 1e-20 74.0 0.1 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DNA_pol_A_exo1 PF01612.15 KFX97114.1 - 5e-09 35.8 0.0 8.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease TcdA_TcdB PF12919.2 KFX97114.1 - 0.081 11.4 3.0 0.19 10.1 0.6 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Reoviridae_Vp9 PF08978.5 KFX97114.1 - 0.11 11.3 0.2 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Reoviridae VP9 THF_DHG_CYH PF00763.18 KFX97117.1 - 1.4e-17 63.8 0.0 2.5e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KFX97117.1 - 8.5e-15 54.1 0.0 3.5e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ERCC4 PF02732.10 KFX97118.1 - 3.7e-19 68.9 0.0 7.3e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain eIF3_subunit PF08597.5 KFX97118.1 - 4.9 6.6 12.1 2.2 7.8 4.4 2.3 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit DUF106 PF01956.11 KFX97119.1 - 3.9e-11 42.7 0.2 5.6e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 ADH_zinc_N PF00107.21 KFX97125.1 - 1.1e-33 115.5 2.8 3e-33 114.1 1.7 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ubiquitin PF00240.18 KFX97125.1 - 3.1e-18 64.9 0.1 5.5e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family ADH_zinc_N_2 PF13602.1 KFX97125.1 - 1.3e-10 42.2 0.1 5.6e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase UBA PF00627.26 KFX97125.1 - 1.5e-07 31.0 0.1 4e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KFX97125.1 - 4.8e-05 22.9 0.0 8.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KFX97125.1 - 0.0001 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFX97125.1 - 0.00091 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ldh_2 PF02615.9 KFX97131.1 - 1.8e-78 263.6 0.1 2e-78 263.4 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase HAD_2 PF13419.1 KFX97133.1 - 3.1e-28 99.1 0.0 3.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX97133.1 - 0.001 19.5 0.0 0.0016 18.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KFX97133.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase bZIP_1 PF00170.16 KFX97134.1 - 4.9e-06 26.3 3.2 8.3e-06 25.6 2.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX97134.1 - 1.3e-05 24.8 3.8 2.3e-05 24.1 2.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFX97134.1 - 0.00034 20.8 5.1 0.0008 19.6 3.5 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2730 PF10805.3 KFX97134.1 - 0.027 14.2 0.8 0.047 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) CAF-1_p150 PF11600.3 KFX97134.1 - 0.18 11.1 3.6 0.29 10.4 2.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1635 PF07795.6 KFX97134.1 - 6.5 6.0 8.5 0.3 10.4 0.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) TPR_12 PF13424.1 KFX97135.1 - 3.2e-45 151.9 16.5 1.1e-11 44.5 0.3 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFX97135.1 - 1.3e-43 145.7 16.1 6.7e-06 25.8 0.1 8.9 9 0 0 9 9 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 KFX97135.1 - 3.7e-23 81.6 10.1 1.5e-07 31.8 0.4 6.0 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 KFX97135.1 - 1.1e-22 78.0 22.0 0.008 16.0 0.1 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 KFX97135.1 - 2.8e-21 74.9 13.5 3.1e-05 23.5 0.4 5.3 1 1 4 6 6 6 6 TPR repeat TPR_6 PF13174.1 KFX97135.1 - 1.3e-20 72.3 15.8 0.017 15.5 0.1 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97135.1 - 1.3e-19 68.9 18.0 0.0062 17.0 0.1 9.1 5 1 4 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFX97135.1 - 7.5e-19 66.0 16.7 0.0087 15.7 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX97135.1 - 8.3e-17 61.2 26.9 0.00073 19.8 2.2 7.5 4 1 3 8 8 7 6 Tetratricopeptide repeat Apc3 PF12895.2 KFX97135.1 - 9.1e-17 60.9 19.0 1.7e-07 31.2 0.2 6.9 3 1 7 10 10 8 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KFX97135.1 - 2.2e-15 55.1 11.6 0.035 13.8 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFX97135.1 - 3.9e-14 51.5 18.3 0.089 12.4 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFX97135.1 - 4.4e-13 49.1 24.0 0.026 14.6 0.2 8.8 2 1 5 9 9 9 4 Tetratricopeptide repeat PPR PF01535.15 KFX97135.1 - 1.3e-11 43.6 2.8 3.1 7.9 0.0 8.8 9 0 0 9 9 8 1 PPR repeat PGAP1 PF07819.8 KFX97135.1 - 1e-06 28.5 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein TPR_17 PF13431.1 KFX97135.1 - 1.4e-06 28.0 13.2 0.33 11.2 0.1 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KFX97135.1 - 4e-06 26.8 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family NB-ARC PF00931.17 KFX97135.1 - 1.9e-05 23.6 0.0 4.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KFX97135.1 - 8.5e-05 22.7 0.1 0.00063 19.8 0.0 2.6 2 0 0 2 2 1 1 AAA domain Vps39_1 PF10366.4 KFX97135.1 - 0.00013 21.9 11.5 0.36 10.8 0.4 6.1 2 2 4 6 6 6 1 Vacuolar sorting protein 39 domain 1 Abhydrolase_5 PF12695.2 KFX97135.1 - 0.00016 21.4 0.0 0.00066 19.4 0.0 2.0 3 0 0 3 3 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KFX97135.1 - 0.00026 20.0 0.0 0.00043 19.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF4248 PF14053.1 KFX97135.1 - 0.00029 20.3 3.4 8.7 6.0 0.0 6.5 8 0 0 8 8 6 0 Domain of unknown function (DUF4248) AAA_16 PF13191.1 KFX97135.1 - 0.00039 20.4 7.3 0.00042 20.3 0.0 3.8 2 2 0 2 2 1 1 AAA ATPase domain Abhydrolase_9 PF10081.4 KFX97135.1 - 0.0007 18.3 0.0 0.033 12.8 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta-hydrolase family UPF0052 PF01933.13 KFX97135.1 - 0.0017 17.7 4.5 3.3 6.9 0.0 5.5 2 1 4 6 6 6 1 Uncharacterised protein family UPF0052 DUF726 PF05277.7 KFX97135.1 - 0.0041 16.0 0.1 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF726) CbiA PF01656.18 KFX97135.1 - 0.0051 16.2 0.0 0.012 14.9 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF676 PF05057.9 KFX97135.1 - 0.0063 15.8 0.0 0.016 14.4 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) TPR_4 PF07721.9 KFX97135.1 - 0.012 15.9 11.8 0.33 11.4 0.3 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 KFX97135.1 - 0.018 15.0 1.8 39 4.3 0.0 5.4 7 0 0 7 7 4 0 PPR repeat family PPR_3 PF13812.1 KFX97135.1 - 0.024 14.8 5.8 72 4.0 0.0 6.3 7 0 0 7 7 5 0 Pentatricopeptide repeat domain DUF627 PF04781.7 KFX97135.1 - 0.025 14.1 2.9 35 4.0 0.0 5.3 6 0 0 6 6 5 0 Protein of unknown function (DUF627) TPR_21 PF09976.4 KFX97135.1 - 0.033 14.1 17.5 1 9.3 1.9 4.4 1 1 6 7 7 7 0 Tetratricopeptide repeat DUF2305 PF10230.4 KFX97135.1 - 0.044 13.1 0.4 0.22 10.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) SRP54 PF00448.17 KFX97135.1 - 0.078 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KFX97135.1 - 0.09 12.3 2.3 0.14 11.6 0.0 2.6 4 0 0 4 4 1 0 AAA domain FerA PF08165.6 KFX97135.1 - 0.13 11.9 10.9 3.4 7.3 0.0 6.1 7 0 0 7 7 6 0 FerA (NUC095) domain Lipase_3 PF01764.20 KFX97135.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 KFX97135.1 - 0.22 11.2 0.0 0.47 10.1 0.0 1.5 1 0 0 1 1 1 0 Cutinase MRP-S27 PF10037.4 KFX97135.1 - 1 8.2 10.7 6.7 5.5 0.1 4.3 5 0 0 5 5 5 0 Mitochondrial 28S ribosomal protein S27 Shikimate_DH PF01488.15 KFX97135.1 - 6 6.9 12.8 31 4.6 0.2 5.1 2 1 3 6 6 5 0 Shikimate / quinate 5-dehydrogenase Gly_transf_sug PF04488.10 KFX97136.1 - 6.8e-09 36.0 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFX97136.1 - 0.006 15.1 0.1 0.0091 14.5 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF4126 PF13548.1 KFX97137.1 - 0.34 10.3 3.9 0.35 10.2 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Fungal_trans PF04082.13 KFX97138.1 - 9.8e-15 54.1 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97138.1 - 1.8e-06 27.7 9.7 3.3e-06 26.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A2M_comp PF07678.9 KFX97140.1 - 0.04 13.1 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 A-macroglobulin complement component Pkinase PF00069.20 KFX97141.1 - 7.2e-58 195.7 0.0 1.3e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97141.1 - 1.3e-31 109.6 0.0 2.1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX97141.1 - 2.4e-14 52.9 0.0 6.2e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Lant_dehyd_C PF04738.8 KFX97141.1 - 0.28 9.3 2.5 1.5 6.9 1.9 1.8 2 0 0 2 2 2 0 Lantibiotic dehydratase, C terminus Pmp3 PF01679.12 KFX97155.1 - 5.3e-20 70.8 5.8 6.5e-20 70.5 4.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sin_N PF04801.8 KFX97156.1 - 5.9e-30 104.4 0.0 9.1e-17 61.0 0.0 2.0 2 0 0 2 2 2 2 Sin-like protein conserved region Clp1 PF06807.9 KFX97157.1 - 2.2e-26 92.8 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KFX97157.1 - 9.7e-14 51.2 0.0 1.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFX97157.1 - 2.6e-08 33.7 0.0 2.9e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFX97157.1 - 3.4e-06 26.9 0.1 1.9e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFX97157.1 - 0.00014 21.9 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 KFX97157.1 - 0.00088 18.7 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KFX97157.1 - 0.0016 18.2 0.3 1.3 8.8 0.0 2.7 2 1 1 3 3 3 2 Dynamin family SRPRB PF09439.5 KFX97157.1 - 0.003 16.7 0.0 0.0076 15.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KFX97157.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_21 PF13304.1 KFX97157.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFX97157.1 - 0.011 15.1 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KFX97157.1 - 0.055 13.7 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.1 KFX97157.1 - 0.077 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 KFX97157.1 - 0.099 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KFX97157.1 - 0.14 11.8 0.0 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 KFX97157.1 - 0.15 11.4 0.0 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain BUD22 PF09073.5 KFX97158.1 - 0.0034 16.5 9.5 0.0052 15.9 6.6 1.2 1 0 0 1 1 1 1 BUD22 Arm PF00514.18 KFX97158.1 - 0.0053 16.5 2.0 0.14 12.0 0.1 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFX97158.1 - 0.022 15.0 0.5 1.5 9.1 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 KFX97158.1 - 0.17 12.4 4.4 5.7 7.5 0.1 4.0 4 0 0 4 4 4 0 HEAT-like repeat Daxx PF03344.10 KFX97158.1 - 0.25 9.7 9.8 0.34 9.3 6.8 1.1 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 KFX97158.1 - 3.5 5.6 7.4 5.6 4.9 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RPA_C PF08784.6 KFX97159.1 - 5.9e-15 55.5 0.1 1.5e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KFX97159.1 - 6e-11 42.0 0.1 1.8e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain FluMu_gp41 PF10109.4 KFX97159.1 - 0.13 12.2 0.1 1.8 8.5 0.0 2.4 1 1 1 2 2 2 0 Mu-like prophage FluMu protein gp41 DnaJ PF00226.26 KFX97160.1 - 3.5e-14 52.2 0.7 3.5e-14 52.2 0.5 2.5 3 0 0 3 3 3 1 DnaJ domain Lon_C PF05362.8 KFX97161.1 - 4.8e-66 221.9 0.4 9.6e-66 220.9 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KFX97161.1 - 2.7e-26 92.5 0.0 6.3e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KFX97161.1 - 1.4e-23 83.5 0.0 5.6e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KFX97161.1 - 2.5e-09 36.6 0.0 5.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KFX97161.1 - 6.9e-09 35.5 0.0 1.9e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFX97161.1 - 3.7e-07 29.7 0.0 7.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KFX97161.1 - 1.6e-05 25.6 0.0 5.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX97161.1 - 1.7e-05 24.9 1.8 4.4e-05 23.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 KFX97161.1 - 2.6e-05 23.8 0.0 8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX97161.1 - 2.8e-05 23.3 0.3 0.00011 21.4 0.1 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KFX97161.1 - 2.9e-05 24.0 0.0 0.0001 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KFX97161.1 - 0.00055 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX97161.1 - 0.00055 20.0 0.0 0.0053 16.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFX97161.1 - 0.0011 17.7 0.5 0.0023 16.7 0.1 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 KFX97161.1 - 0.0011 18.6 0.0 0.0041 16.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KFX97161.1 - 0.0024 17.7 0.0 0.0068 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFX97161.1 - 0.005 16.2 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFX97161.1 - 0.0053 16.9 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase Zeta_toxin PF06414.7 KFX97161.1 - 0.0084 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KFX97161.1 - 0.0088 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 KFX97161.1 - 0.012 15.9 0.1 0.03 14.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFX97161.1 - 0.015 15.6 0.0 0.015 15.6 0.0 2.6 1 1 1 2 2 1 0 AAA domain G-alpha PF00503.15 KFX97161.1 - 0.015 13.9 0.1 0.026 13.2 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.1 KFX97161.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFX97161.1 - 0.019 14.6 0.0 0.45 10.1 0.0 2.7 1 1 1 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KFX97161.1 - 0.02 14.5 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KFX97161.1 - 0.021 13.9 0.1 0.073 12.2 0.1 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KFX97161.1 - 0.028 13.6 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFX97161.1 - 0.045 13.4 0.6 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.6 KFX97161.1 - 0.052 12.2 0.1 0.48 9.0 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain MobB PF03205.9 KFX97161.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KFX97161.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KFX97161.1 - 0.066 13.5 0.0 0.26 11.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.10 KFX97161.1 - 0.097 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Pribosyltran PF00156.22 KFX97171.1 - 8.2e-18 64.3 0.0 1.1e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFX97171.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase_Tyr PF07714.12 KFX97192.1 - 2.5e-18 66.0 0.0 4.6e-17 61.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFX97192.1 - 5.5e-18 65.0 0.0 7.3e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX97192.1 - 0.0049 16.6 2.0 0.0086 15.8 0.7 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX97192.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KFX97192.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Cellulase PF00150.13 KFX97200.1 - 2.2e-30 105.8 0.4 4.2e-30 104.9 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_20 PF00728.17 KFX97201.1 - 7e-38 130.6 0.1 2.6e-37 128.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KFX97201.1 - 1.1e-09 38.8 0.0 2.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 HeLo PF14479.1 KFX97204.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation Kdo PF06293.9 KFX97204.1 - 0.06 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KFX97204.1 - 0.19 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase zf-RanBP PF00641.13 KFX97206.1 - 5.2e-12 44.6 1.1 7.5e-12 44.1 0.8 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KFX97206.1 - 1e-08 34.6 0.0 1.4e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97206.1 - 2.5e-06 27.3 0.0 4.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KFX97206.1 - 0.1 12.4 1.7 0.13 12.0 0.7 1.5 2 0 0 2 2 2 0 Double zinc ribbon Coatomer_E PF04733.9 KFX97209.1 - 1.9e-57 194.6 10.0 2.1e-57 194.5 6.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KFX97209.1 - 1.5e-12 47.6 23.3 8.6e-05 22.8 0.6 4.7 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97209.1 - 1.2e-09 37.9 19.1 2.6e-06 27.5 0.1 5.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX97209.1 - 2e-09 37.8 19.5 0.00011 22.7 0.0 4.9 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX97209.1 - 1.2e-08 34.4 7.9 2.8e-07 30.0 0.0 3.9 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.1 KFX97209.1 - 7.2e-06 26.1 7.9 0.0065 16.8 0.0 5.6 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFX97209.1 - 7.1e-05 22.8 11.2 0.36 11.3 0.2 5.4 4 1 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX97209.1 - 8.5e-05 22.6 6.7 0.0065 16.5 0.2 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFX97209.1 - 0.00034 20.3 17.4 0.00089 18.9 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX97209.1 - 0.00035 20.5 2.5 0.055 13.6 0.0 4.6 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX97209.1 - 0.0016 18.0 3.4 1.7 8.6 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX97209.1 - 0.0029 17.4 12.5 0.13 12.2 0.0 4.6 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFX97209.1 - 0.0071 15.9 0.0 0.0071 15.9 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_5 PF12688.2 KFX97209.1 - 0.014 15.3 7.6 1.7 8.7 3.2 2.8 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_15 PF13429.1 KFX97209.1 - 0.047 12.7 9.8 0.41 9.6 2.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat PrgU PF09627.5 KFX97209.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PrgU-like protein TPR_21 PF09976.4 KFX97209.1 - 0.1 12.5 22.3 0.093 12.6 0.5 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF1488 PF07369.6 KFX97209.1 - 0.82 9.5 3.2 5.3 6.9 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) TPR_7 PF13176.1 KFX97209.1 - 1.7 8.6 8.5 21 5.2 0.0 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFX97209.1 - 1.8 8.4 8.6 3.7 7.4 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Apc5 PF12862.2 KFX97209.1 - 3.8 7.4 12.3 0.23 11.3 0.2 4.0 3 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 HAD PF12710.2 KFX97211.1 - 3.6e-12 46.8 0.0 5.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFX97211.1 - 0.003 16.7 0.0 0.19 10.8 0.0 2.4 3 0 0 3 3 3 1 Putative Phosphatase Herpes_US12 PF05363.7 KFX97211.1 - 0.028 14.9 0.0 11 6.5 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus US12 family Hydrolase PF00702.21 KFX97211.1 - 0.039 14.3 0.1 0.35 11.2 0.1 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFX97211.1 - 0.092 12.0 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Lipase_GDSL_2 PF13472.1 KFX97212.1 - 4e-09 36.8 0.0 1.1e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Rhomboid PF01694.17 KFX97212.1 - 0.73 9.8 3.8 0.94 9.4 0.4 2.2 2 0 0 2 2 2 0 Rhomboid family Chitin_synth_2 PF03142.10 KFX97217.1 - 1e-253 842.5 0.3 2.3e-253 841.3 0.4 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 KFX97217.1 - 4.6e-147 490.9 0.0 6e-147 490.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KFX97217.1 - 9.4e-16 57.3 0.1 2.4e-14 52.8 0.0 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 KFX97217.1 - 1.2e-15 57.7 3.1 1.2e-15 57.7 2.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFX97217.1 - 1.6e-15 57.5 0.1 8.6e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KFX97217.1 - 4.5e-13 48.8 0.0 2.3e-10 40.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KFX97217.1 - 0.00012 21.7 0.0 0.046 13.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KFX97217.1 - 0.04 13.2 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 BDV_P40 PF06407.6 KFX97219.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P40 protein Cellulase PF00150.13 KFX97220.1 - 3.6e-51 174.0 0.1 5e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFX97220.1 - 3.5e-12 45.7 14.0 3.5e-12 45.7 9.7 3.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX97220.1 - 0.52 10.3 3.8 1.3 9.1 2.6 1.7 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_10 PF00331.15 KFX97221.1 - 4.6e-103 344.6 0.2 5.3e-103 344.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KFX97221.1 - 3.2e-08 33.0 7.8 3.2e-08 33.0 5.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.8 KFX97222.1 - 2.9e-147 488.9 11.5 3.5e-147 488.7 8.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 KFX97222.1 - 4.6e-12 45.3 15.9 1.4e-11 43.8 11.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.13 KFX97223.1 - 1.7e-07 30.7 10.4 1.7e-07 30.7 7.2 3.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KFX97223.1 - 2.3e-05 24.1 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFX97223.1 - 0.0023 17.2 0.5 0.01 15.1 0.2 2.1 1 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX97223.1 - 0.0063 15.7 0.0 0.027 13.6 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 KFX97223.1 - 0.0081 15.6 1.6 0.037 13.4 1.1 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KFX97223.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFX97223.1 - 0.041 13.7 0.0 0.055 13.3 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family MLTD_N PF06474.7 KFX97223.1 - 0.08 13.1 0.4 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 MltD lipid attachment motif MSP1_C PF07462.6 KFX97223.1 - 0.18 10.1 0.2 0.23 9.8 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Abhydrolase_6 PF12697.2 KFX97224.1 - 3.2e-19 69.7 0.0 4.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX97224.1 - 3e-10 40.0 0.0 3.8e-10 39.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX97224.1 - 4.5e-05 23.1 0.0 0.0061 16.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Zeta_toxin PF06414.7 KFX97224.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RhoGEF PF00621.15 KFX97226.1 - 7.7e-26 91.0 0.0 1.6e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 KFX97226.1 - 0.021 14.2 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) EzrA PF06160.7 KFX97226.1 - 0.054 11.6 0.0 0.054 11.6 0.0 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Glyco_trans_1_3 PF13528.1 KFX97226.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Seryl_tRNA_N PF02403.17 KFX97226.1 - 1.8 8.5 11.8 0.84 9.6 4.5 3.0 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Carn_acyltransf PF00755.15 KFX97227.1 - 7.5e-163 542.7 0.0 2e-148 495.1 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase TPR_12 PF13424.1 KFX97228.1 - 2.2e-32 110.7 3.9 6.7e-13 48.3 0.0 4.3 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFX97228.1 - 6.3e-31 105.3 7.9 1.7e-06 27.7 0.0 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFX97228.1 - 2.3e-11 42.5 3.4 0.0033 17.1 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFX97228.1 - 7.4e-11 41.1 4.5 0.011 15.5 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFX97228.1 - 7.6e-09 34.8 0.6 0.005 16.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97228.1 - 2.1e-08 34.0 3.3 1.6 9.5 0.0 5.8 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX97228.1 - 5.9e-08 32.2 2.9 0.25 11.0 0.0 4.4 3 1 3 6 6 6 4 TPR repeat TPR_16 PF13432.1 KFX97228.1 - 1.6e-06 28.5 0.8 2 9.1 0.0 4.2 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX97228.1 - 2.5e-05 23.7 0.1 3.9 7.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX97228.1 - 0.00033 20.6 0.3 1.5 9.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX97228.1 - 0.0072 16.6 4.2 1.1 9.6 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX97228.1 - 0.022 15.2 1.1 5.6 7.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 KFX97228.1 - 0.026 13.9 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 KFX97228.1 - 0.16 12.4 2.0 17 6.1 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat MFS_1 PF07690.11 KFX97229.1 - 4.4e-30 104.6 68.2 9.7e-25 87.0 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX97229.1 - 4.2e-07 28.7 23.2 0.00028 19.4 5.4 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 KFX97229.1 - 0.038 12.4 17.8 0.023 13.2 9.9 2.3 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like TPR_12 PF13424.1 KFX97230.1 - 2.8e-35 120.1 12.8 1.5e-09 37.6 0.0 6.1 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFX97230.1 - 1.1e-15 56.9 1.2 0.055 13.4 0.0 8.2 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFX97230.1 - 1.1e-07 31.1 5.4 0.32 10.9 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97230.1 - 2.9e-05 24.3 4.2 0.066 13.8 0.1 4.8 5 0 0 5 5 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 KFX97230.1 - 5.3e-05 23.3 0.0 0.00023 21.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 KFX97230.1 - 5.8e-05 23.6 0.1 0.031 14.9 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX97230.1 - 0.00014 22.1 2.9 0.85 10.0 0.0 4.4 3 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX97230.1 - 0.00031 20.4 6.1 3.7 7.7 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX97230.1 - 0.00037 19.9 0.4 11 5.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFX97230.1 - 0.00044 19.8 6.1 0.86 9.2 0.1 5.0 4 1 2 6 6 6 1 TPR repeat Apc3 PF12895.2 KFX97230.1 - 0.0018 18.3 0.2 0.36 11.0 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KFX97230.1 - 0.0019 18.0 3.7 11 6.1 0.1 4.7 5 0 0 5 5 5 0 PPR repeat TPR_8 PF13181.1 KFX97230.1 - 0.0029 17.2 4.5 26 4.9 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_16 PF13191.1 KFX97230.1 - 0.0033 17.4 0.1 0.035 14.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain TPR_4 PF07721.9 KFX97230.1 - 0.0034 17.6 0.1 0.99 10.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc5 PF12862.2 KFX97230.1 - 0.058 13.2 0.0 4.9 7.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 p450 PF00067.17 KFX97231.1 - 2.7e-59 200.8 0.0 3.8e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 KFX97232.1 - 1.7e-05 23.5 0.3 2.7e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTAD PF03704.12 KFX97232.1 - 0.017 15.3 0.7 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Glyco_transf_28 PF03033.15 KFX97233.1 - 5.2e-18 65.1 0.1 1.2e-14 54.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX97233.1 - 0.00017 20.2 0.0 0.0003 19.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 KFX97233.1 - 0.0052 16.2 0.2 1.6 8.4 0.0 3.5 3 0 0 3 3 3 1 Ubiquitin interaction motif Glyco_tran_28_C PF04101.11 KFX97233.1 - 0.0069 16.0 0.1 0.098 12.3 0.0 2.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain zf-AN1 PF01428.11 KFX97234.1 - 0.2 11.5 3.2 0.41 10.5 2.2 1.6 1 1 0 1 1 1 0 AN1-like Zinc finger DUF2306 PF10067.4 KFX97236.1 - 4.4e-11 42.8 9.9 4.4e-11 42.8 6.9 2.2 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) SCAMP PF04144.8 KFX97236.1 - 1.9 8.3 12.6 0.85 9.4 4.8 2.3 2 0 0 2 2 2 0 SCAMP family Zn_clus PF00172.13 KFX97237.1 - 1.5e-07 31.2 7.7 2.4e-07 30.5 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX97237.1 - 0.001 17.7 0.0 0.0026 16.4 0.0 1.6 1 1 0 2 2 2 1 Fungal specific transcription factor domain LysM PF01476.15 KFX97238.1 - 2.6e-24 84.8 5.0 8.4e-08 31.9 0.2 4.5 4 0 0 4 4 4 4 LysM domain HTH_Tnp_1 PF01527.15 KFX97238.1 - 4.1e-05 23.4 0.0 0.085 12.8 0.0 3.2 4 0 0 4 4 4 2 Transposase HTH_23 PF13384.1 KFX97238.1 - 0.0026 17.3 0.2 5.3 6.8 0.0 3.4 3 0 0 3 3 3 2 Homeodomain-like domain Fer2_4 PF13510.1 KFX97238.1 - 0.019 14.7 1.0 2.8 7.7 0.1 2.7 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Cul7 PF11515.3 KFX97238.1 - 0.03 14.2 0.0 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 Mouse development and cellular proliferation protein Cullin-7 HTH_28 PF13518.1 KFX97238.1 - 0.098 12.6 0.3 41 4.3 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain ABC_tran PF00005.22 KFX97240.1 - 4.7e-43 146.7 0.1 9.7e-23 80.9 0.3 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX97240.1 - 5.1e-35 121.2 30.7 5.6e-26 91.5 6.3 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX97240.1 - 3.6e-09 37.0 2.5 0.0039 17.2 0.7 3.6 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 KFX97240.1 - 7.4e-08 32.6 0.1 0.00071 19.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFX97240.1 - 8.7e-08 31.6 1.1 9.9e-05 21.6 0.2 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX97240.1 - 1.4e-06 27.7 1.4 0.051 13.1 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFX97240.1 - 2.2e-06 27.3 0.5 0.008 15.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 KFX97240.1 - 5.2e-06 26.9 2.7 0.00082 19.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX97240.1 - 2.3e-05 24.4 0.3 0.007 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KFX97240.1 - 3.1e-05 23.2 1.3 0.028 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFX97240.1 - 0.00012 21.6 1.2 0.065 12.6 0.3 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 KFX97240.1 - 0.00021 20.7 0.2 0.13 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX97240.1 - 0.00031 19.7 3.0 0.19 10.5 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 KFX97240.1 - 0.00045 19.9 0.1 0.015 14.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 KFX97240.1 - 0.0014 19.1 0.9 0.35 11.3 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 KFX97240.1 - 0.0014 18.3 0.2 0.064 12.9 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 KFX97240.1 - 0.0018 18.1 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX97240.1 - 0.0028 17.5 1.0 1.1 9.2 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KFX97240.1 - 0.004 16.2 0.3 1.1 8.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 KFX97240.1 - 0.0077 16.3 0.2 0.7 10.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 KFX97240.1 - 0.0078 17.0 0.4 5.8 7.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KFX97240.1 - 0.0084 15.2 0.1 0.0084 15.2 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.17 KFX97240.1 - 0.013 14.3 0.7 0.041 12.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 KFX97240.1 - 0.014 15.2 0.1 0.24 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFX97240.1 - 0.015 15.0 1.4 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KFX97240.1 - 0.015 14.4 0.4 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI LysM PF01476.15 KFX97240.1 - 0.016 15.1 0.0 7 6.6 0.0 2.7 2 0 0 2 2 2 0 LysM domain Adeno_IVa2 PF02456.10 KFX97240.1 - 0.09 11.4 0.8 0.52 8.8 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 KFX97240.1 - 0.092 12.5 1.1 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 KFX97240.1 - 0.11 12.3 5.0 0.3 10.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 KFX97240.1 - 0.17 12.0 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 KFX97240.1 - 0.18 11.2 0.7 0.67 9.3 0.1 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA_5 PF07728.9 KFX97240.1 - 0.19 11.4 0.1 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KFX97240.1 - 0.26 11.5 1.1 13 6.1 0.2 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KFX97240.1 - 0.27 10.6 2.4 2.7 7.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 KFX97240.1 - 0.3 10.3 0.9 22 4.2 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein RNA12 PF10443.4 KFX97240.1 - 0.41 9.0 0.2 1.3 7.4 0.0 1.7 2 0 0 2 2 2 0 RNA12 protein KH_2 PF07650.12 KFX97240.1 - 0.49 9.9 0.4 21 4.7 0.0 2.4 2 0 0 2 2 2 0 KH domain AAA PF00004.24 KFX97248.1 - 3.9e-47 159.7 0.0 5.1e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX97248.1 - 1.2e-06 28.6 0.1 1.9e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFX97248.1 - 2.6e-06 26.6 0.0 5.4e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFX97248.1 - 4.5e-06 26.8 0.0 0.00058 20.0 0.0 2.5 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 KFX97248.1 - 7.5e-05 21.9 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 KFX97248.1 - 9.3e-05 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFX97248.1 - 0.00015 21.4 0.1 0.0013 18.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX97248.1 - 0.0002 21.2 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX97248.1 - 0.0004 20.2 0.0 0.00096 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX97248.1 - 0.00074 19.2 0.6 0.0057 16.3 0.1 2.6 2 1 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KFX97248.1 - 0.00085 18.7 0.4 0.97 8.7 0.2 2.3 1 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KFX97248.1 - 0.0011 18.6 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_17 PF13207.1 KFX97248.1 - 0.0022 18.8 0.0 0.0039 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFX97248.1 - 0.0022 17.1 0.1 0.0098 15.0 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KFX97248.1 - 0.0033 16.3 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KFX97248.1 - 0.0034 16.8 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFX97248.1 - 0.0039 15.9 0.0 0.0056 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 KFX97248.1 - 0.0085 16.1 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.21 KFX97248.1 - 0.01 15.2 0.0 0.036 13.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KFX97248.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KFX97248.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 KFX97248.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFX97248.1 - 0.014 15.1 0.0 0.28 10.8 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 KFX97248.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 KFX97248.1 - 0.027 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 KFX97248.1 - 0.036 14.3 0.0 0.064 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KFX97248.1 - 0.036 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KFX97248.1 - 0.038 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin2 PF13189.1 KFX97248.1 - 0.062 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Bac_DnaA PF00308.13 KFX97248.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein SKI PF01202.17 KFX97248.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.1 KFX97248.1 - 0.16 11.4 0.1 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KFX97248.1 - 0.19 10.3 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2293 PF10056.4 KFX97249.1 - 1.3e-25 89.2 0.1 2.9e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Mito_carr PF00153.22 KFX97250.1 - 2.2e-43 145.8 11.0 1.8e-17 62.8 0.6 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.20 KFX97251.1 - 1.3e-36 124.3 0.3 6.3e-22 77.2 0.1 2.5 2 0 0 2 2 2 2 Bromodomain RNase_PH PF01138.16 KFX97252.1 - 2.7e-16 60.1 0.0 9.1e-16 58.3 0.0 1.9 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KFX97252.1 - 0.017 15.0 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ATE_C PF04377.10 KFX97253.1 - 4.4e-41 139.9 0.2 9.8e-41 138.8 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KFX97253.1 - 3.4e-19 68.4 2.9 6.2e-19 67.5 1.4 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KFX97253.1 - 0.0019 18.1 0.2 0.006 16.5 0.2 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Kinesin PF00225.18 KFX97256.1 - 8.1e-114 379.8 0.3 1.6e-113 378.7 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain RolB_RolC PF02027.12 KFX97256.1 - 0.065 12.3 5.0 0.078 12.1 0.3 2.4 2 0 0 2 2 2 0 RolB/RolC glucosidase family DUF3166 PF11365.3 KFX97256.1 - 0.86 10.0 16.6 0.24 11.8 2.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) UQ_con PF00179.21 KFX97257.1 - 1.1e-51 173.9 0.0 1.2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX97257.1 - 4.2e-06 26.5 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFX97257.1 - 0.021 14.7 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KFX97257.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain Thiolase_N PF00108.18 KFX97258.1 - 1.8e-92 309.0 0.8 2.8e-92 308.4 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX97258.1 - 1.6e-36 124.4 1.3 4e-36 123.1 0.9 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFX97258.1 - 0.0027 17.2 0.9 0.0098 15.3 0.6 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DJ-1_PfpI PF01965.19 KFX97259.1 - 5.6e-11 42.0 0.0 8.8e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DUF1524 PF07510.6 KFX97264.1 - 1.9e-14 53.7 0.0 2.1e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KFX97264.1 - 0.018 14.6 0.4 0.059 13.0 0.3 1.8 1 1 0 1 1 1 0 HNH endonuclease Acyl-CoA_dh_1 PF00441.19 KFX97265.1 - 2.5e-25 89.3 0.4 4.9e-25 88.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX97265.1 - 5.1e-17 61.1 0.0 1.3e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1 PF01926.18 KFX97265.1 - 6e-17 61.6 0.2 3.1e-15 56.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Acyl-CoA_dh_2 PF08028.6 KFX97265.1 - 4.7e-14 52.7 0.5 1.4e-13 51.2 0.4 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX97265.1 - 1.2e-10 41.9 0.0 4.5e-10 40.1 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FeoB_N PF02421.13 KFX97265.1 - 3.4e-07 29.6 0.2 2e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX97265.1 - 0.00011 21.4 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFX97265.1 - 0.0091 15.8 6.1 0.094 12.5 0.1 3.1 4 0 0 4 4 4 2 Dynamin family AIG1 PF04548.11 KFX97265.1 - 0.01 14.9 0.1 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 KFX97265.1 - 0.072 13.5 1.6 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Astro_capsid PF03115.9 KFX97265.1 - 0.099 10.8 1.1 0.16 10.2 0.8 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor LTV PF04180.9 KFX97266.1 - 1.1e-94 318.3 15.6 1.3e-94 318.1 10.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein GST_N_3 PF13417.1 KFX97267.1 - 5.9e-06 26.4 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX97267.1 - 7.6e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX97267.1 - 7.9e-05 23.0 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX97267.1 - 8e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX97267.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Spo12 PF05032.7 KFX97268.1 - 7.7e-15 54.2 2.2 2.2e-14 52.7 1.2 2.0 2 0 0 2 2 2 1 Spo12 family AMP-binding PF00501.23 KFX97278.1 - 9.9e-168 557.8 2.3 5.5e-74 249.0 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFX97278.1 - 8.7e-111 369.5 0.0 8.4e-38 129.9 0.0 5.0 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.20 KFX97278.1 - 4.5e-19 68.4 0.2 1.5e-09 37.9 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KFX97278.1 - 0.0088 16.3 0.9 0.26 11.6 0.0 3.1 3 0 0 3 3 3 1 HxxPF-repeated domain Amidase PF01425.16 KFX97279.1 - 4e-92 309.3 0.0 4.9e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 KFX97280.1 - 9.4e-30 103.5 67.5 1.5e-15 56.7 23.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX97280.1 - 0.0064 14.9 36.4 0.034 12.5 13.1 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein CRCB PF02537.10 KFX97281.1 - 2e-29 101.8 23.4 2.9e-19 69.0 6.2 3.6 3 1 0 3 3 3 3 CrcB-like protein Sel1 PF08238.7 KFX97282.1 - 8.5e-34 115.2 26.2 8.8e-06 26.1 0.2 7.8 7 0 0 7 7 7 6 Sel1 repeat Hce2 PF14856.1 KFX97282.1 - 1e-13 50.9 0.0 2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor TPR_6 PF13174.1 KFX97282.1 - 1.8 9.1 11.1 1.3 9.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CBP4 PF07960.6 KFX97283.1 - 2.1e-36 124.3 0.7 2.5e-36 124.0 0.5 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 KFX97283.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Seryl_tRNA_N PF02403.17 KFX97283.1 - 0.033 14.2 5.3 0.049 13.6 3.7 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2852 PF11014.3 KFX97283.1 - 1.3 8.9 5.2 0.93 9.4 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Ribosomal_L24e PF01246.15 KFX97284.1 - 7.3e-30 102.6 0.7 7.3e-30 102.6 0.5 1.8 2 1 0 2 2 2 1 Ribosomal protein L24e WTX PF09422.5 KFX97284.1 - 0.064 12.2 5.3 0.072 12.0 3.7 1.0 1 0 0 1 1 1 0 WTX protein Tom37_C PF11801.3 KFX97284.1 - 3.4 7.4 4.8 3.7 7.3 2.9 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain AdoMet_MTase PF07757.8 KFX97285.1 - 7.5e-40 135.5 0.0 1.2e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KFX97285.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFX97285.1 - 0.014 15.0 0.0 0.062 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97285.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NAC PF01849.13 KFX97286.1 - 3.8e-20 71.1 0.2 6.6e-20 70.3 0.2 1.4 1 0 0 1 1 1 1 NAC domain Nup35_RRM PF05172.8 KFX97287.1 - 0.0019 17.9 0.0 0.0044 16.7 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAM53 PF15242.1 KFX97287.1 - 0.0042 16.6 1.4 0.0042 16.6 1.0 1.7 2 0 0 2 2 2 1 Family of FAM53 DUF1687 PF07955.6 KFX97288.1 - 7.1e-18 64.8 0.1 4.9e-17 62.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Metallophos PF00149.23 KFX97289.1 - 7.4e-08 32.0 1.5 1.4e-07 31.1 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_5 PF13893.1 KFX97289.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX97289.1 - 0.0039 16.7 0.0 0.0099 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97289.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 5_nucleotid_C PF02872.13 KFX97289.1 - 0.009 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain DUF619 PF04768.8 KFX97290.1 - 1.4e-50 171.0 0.5 2.6e-50 170.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KFX97290.1 - 9.6e-30 103.3 0.0 2.5e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KFX97290.1 - 1.4e-25 90.2 0.0 2.5e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KFX97290.1 - 0.034 14.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus YjbR PF04237.8 KFX97290.1 - 0.037 14.3 0.2 3.5 8.0 0.0 3.2 3 0 0 3 3 3 0 YjbR Synaptobrevin PF00957.16 KFX97291.1 - 2.3e-27 94.4 1.1 2.8e-27 94.1 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 KFX97291.1 - 0.00018 21.1 0.3 0.00027 20.5 0.2 1.3 1 0 0 1 1 1 1 Retroviral envelope protein EMP24_GP25L PF01105.19 KFX97291.1 - 0.029 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sigma_reg_N PF13800.1 KFX97291.1 - 0.079 13.0 1.8 0.54 10.3 1.8 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Tenui_PVC2 PF06656.6 KFX97291.1 - 0.15 9.8 0.0 0.17 9.6 0.0 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein DUF2937 PF11157.3 KFX97291.1 - 0.28 10.5 1.2 0.29 10.4 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Fzo_mitofusin PF04799.8 KFX97291.1 - 0.68 9.2 2.7 0.31 10.4 0.3 1.5 1 1 1 2 2 2 0 fzo-like conserved region Glyco_hydro_76 PF03663.9 KFX97292.1 - 1.8e-154 514.5 15.8 2.4e-154 514.2 11.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MFS_1 PF07690.11 KFX97294.1 - 3.8e-36 124.5 53.9 1.6e-30 106.0 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97294.1 - 2.4e-10 39.6 2.7 2.4e-10 39.6 1.9 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX97294.1 - 9.1e-05 21.0 2.6 9.1e-05 21.0 1.8 3.2 2 2 2 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 KFX97294.1 - 0.012 13.8 1.1 0.017 13.3 0.2 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KFX97294.1 - 0.016 15.0 1.1 1.1 9.0 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family Cupin_1 PF00190.17 KFX97295.1 - 5.3e-12 45.3 0.1 7.6e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KFX97295.1 - 0.00039 19.8 0.1 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MARVEL PF01284.18 KFX97296.1 - 0.001 18.8 14.8 0.039 13.7 9.3 2.1 1 1 1 2 2 2 2 Membrane-associating domain DUF4418 PF14387.1 KFX97296.1 - 0.052 13.2 0.5 0.052 13.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Glyoxalase_2 PF12681.2 KFX97297.1 - 1.2e-07 32.2 0.1 1.5e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFX97297.1 - 0.00042 20.2 0.3 0.0011 18.8 0.2 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_2 PF02230.11 KFX97308.1 - 2.7e-56 190.4 0.0 4.2e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LigB PF02900.13 KFX97308.1 - 1e-46 159.1 0.0 3.1e-46 157.5 0.0 1.7 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_5 PF12695.2 KFX97308.1 - 2.8e-09 36.8 0.0 6.9e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX97308.1 - 4.6e-05 22.7 0.4 0.0085 15.3 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFX97308.1 - 5.2e-05 23.2 0.3 0.0031 17.4 0.1 2.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KFX97308.1 - 7e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 KFX97308.1 - 0.00019 20.9 0.0 0.00041 19.8 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFX97308.1 - 0.031 13.8 0.0 3.7 7.0 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFX97308.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) MIT PF04212.13 KFX97309.1 - 1e-17 63.7 4.9 2.7e-17 62.4 3.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FAD-oxidase_C PF02913.14 KFX97309.1 - 1.3e-16 60.7 0.0 2.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFX97309.1 - 1.6e-15 56.8 0.0 4.7e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 KFX97310.1 - 1.5e-18 67.2 0.1 1.7e-17 63.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX97310.1 - 1.8e-09 37.7 0.1 6.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX97310.1 - 3.3e-08 33.4 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX97310.1 - 0.00011 22.2 0.3 0.00047 20.2 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX97310.1 - 0.00023 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CDC48_N PF02359.13 KFX97310.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain 3Beta_HSD PF01073.14 KFX97310.1 - 0.12 11.0 0.1 0.22 10.2 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.13 KFX97311.1 - 3.2e-18 65.5 0.3 6.5e-18 64.5 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97311.1 - 4.2e-06 26.5 12.3 7.7e-06 25.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX97312.1 - 7.3e-26 91.0 1.3 1e-25 90.6 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX97312.1 - 2.2e-15 56.7 0.5 3.2e-15 56.2 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX97312.1 - 4.1e-10 39.8 0.0 5.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX97312.1 - 3.8e-07 29.8 0.1 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX97312.1 - 7.6e-06 25.0 0.1 9.2e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX97312.1 - 0.016 14.0 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KFX97312.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 KFX97313.1 - 9.7e-07 28.6 11.7 9.7e-07 28.6 8.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFX97313.1 - 0.0036 17.5 1.2 0.018 15.3 0.9 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFX97313.1 - 0.088 12.9 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AA_permease_2 PF13520.1 KFX97318.1 - 2e-57 194.6 51.5 2.4e-57 194.3 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX97318.1 - 1.4e-17 63.2 42.0 1.9e-17 62.7 29.1 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ca_ex PF01699.19 KFX97319.1 - 2.7e-28 98.3 23.3 5.5e-16 58.4 3.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IncA PF04156.9 KFX97319.1 - 0.0023 17.5 0.3 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 IncA protein CVNH PF08881.5 KFX97320.1 - 1.7e-09 37.7 0.2 1.5e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 CVNH domain NPP1 PF05630.6 KFX97321.1 - 2.4e-59 200.5 1.4 3.8e-59 199.9 0.7 1.4 2 0 0 2 2 2 1 Necrosis inducing protein (NPP1) Mito_fiss_reg PF05308.6 KFX97321.1 - 9.2 5.5 13.2 2.2 7.5 6.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Sedlin_N PF04628.8 KFX97323.1 - 4e-36 123.7 0.0 6e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF77 PF01910.12 KFX97323.1 - 5.7e-27 93.2 0.2 9.5e-27 92.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF77 L31 PF09784.4 KFX97324.1 - 1.9e-43 146.7 3.4 2.1e-43 146.5 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 YpzI PF14140.1 KFX97324.1 - 0.079 12.4 2.2 0.59 9.6 0.1 2.2 2 0 0 2 2 2 0 YpzI-like protein RRM_1 PF00076.17 KFX97325.1 - 9.6e-15 53.9 0.0 1.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97325.1 - 1.1e-10 41.3 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX97325.1 - 1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP72 PF08492.7 KFX97326.1 - 1.7e-12 47.5 6.2 1.7e-12 47.5 4.3 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain Nup88 PF10168.4 KFX97326.1 - 2.2e-05 22.5 1.5 0.012 13.4 0.0 2.4 2 0 0 2 2 2 2 Nuclear pore component THOC7 PF05615.8 KFX97326.1 - 0.0055 16.9 2.1 0.019 15.2 1.4 1.9 1 0 0 1 1 1 1 Tho complex subunit 7 Apc3 PF12895.2 KFX97326.1 - 0.0061 16.6 1.4 0.47 10.6 0.1 3.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KFX97326.1 - 0.012 15.5 1.7 17 5.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX97326.1 - 0.014 15.7 8.8 9.6 6.6 0.9 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat CNP1 PF08750.6 KFX97326.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 CNP1-like family Hormone_1 PF00103.15 KFX97326.1 - 0.12 11.6 2.8 0.93 8.7 0.3 2.5 1 1 1 2 2 2 0 Somatotropin hormone family TPR_16 PF13432.1 KFX97326.1 - 9.3 7.0 10.3 4.3 8.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97326.1 - 9.6 7.1 12.1 1.5e+02 3.4 0.8 6.0 4 3 3 7 7 7 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.7 KFX97327.1 - 2e-39 134.6 0.3 3.2e-39 133.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Epimerase PF01370.16 KFX97329.1 - 6.7e-18 64.9 0.0 9.6e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX97329.1 - 1.1e-09 37.5 0.0 1.1e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFX97329.1 - 1.6e-08 33.5 0.0 5e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX97329.1 - 1.5e-05 25.0 0.0 5.5e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX97329.1 - 5.8e-05 23.0 0.0 0.00013 21.9 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX97329.1 - 0.0056 16.3 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 KR domain DEAD PF00270.24 KFX97330.1 - 2.6e-41 140.9 1.7 4.2e-41 140.2 1.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX97330.1 - 1.8e-22 78.9 0.0 2.9e-11 43.0 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFX97330.1 - 4e-05 23.5 0.2 0.00013 21.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_M19 PF01244.16 KFX97330.1 - 0.049 12.5 0.1 0.099 11.5 0.1 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) RdRP PF05183.7 KFX97331.1 - 1.5e-116 390.4 0.0 2.2e-116 389.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF4062 PF13271.1 KFX97331.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) peroxidase PF00141.18 KFX97332.1 - 1.1e-48 165.6 0.0 1.6e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Lipase_3 PF01764.20 KFX97333.1 - 2.6e-16 59.4 0.0 4.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Integrin_alpha PF00357.15 KFX97333.1 - 2.1 8.3 4.6 26 4.9 0.2 2.8 2 0 0 2 2 2 0 Integrin alpha cytoplasmic region CENP-B_dimeris PF09026.5 KFX97335.1 - 0.00046 20.3 4.2 0.00087 19.4 2.9 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KFX97335.1 - 0.0024 17.3 0.3 0.0037 16.7 0.2 1.3 1 0 0 1 1 1 1 Nucleoplasmin Gly-zipper_OmpA PF13436.1 KFX97335.1 - 0.0099 15.5 2.0 0.02 14.5 1.4 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Sigma70_ner PF04546.8 KFX97335.1 - 0.013 15.1 2.5 0.022 14.3 1.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2254 PF10011.4 KFX97335.1 - 0.042 12.3 0.0 0.062 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Mito_carr PF00153.22 KFX97336.1 - 3.7e-70 231.6 3.5 7.9e-25 86.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dna2 PF08696.6 KFX97337.1 - 2.4e-70 236.0 0.4 4.5e-70 235.2 0.3 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KFX97337.1 - 6e-51 172.6 0.0 1.1e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFX97337.1 - 5.2e-39 134.2 0.6 1.2e-19 70.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KFX97337.1 - 3e-12 46.5 0.0 8.1e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX97337.1 - 1.4e-11 43.9 0.2 4.2e-11 42.4 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 KFX97337.1 - 3.3e-09 36.8 0.2 4.5e-08 33.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 KFX97337.1 - 3.7e-08 33.0 0.1 7.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KFX97337.1 - 2.7e-06 27.0 1.3 0.31 10.5 0.0 4.0 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase DUF911 PF06023.7 KFX97337.1 - 8.2e-05 21.9 0.1 0.00027 20.2 0.1 1.7 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) PIF1 PF05970.9 KFX97337.1 - 0.00027 19.9 0.0 0.00063 18.7 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase Helicase_RecD PF05127.9 KFX97337.1 - 0.00028 20.5 0.0 0.00078 19.1 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KFX97337.1 - 0.00032 20.1 0.1 0.00078 18.8 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 KFX97337.1 - 0.00055 19.4 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KFX97337.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 KFX97337.1 - 0.002 17.8 0.1 0.0046 16.6 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KFX97337.1 - 0.0033 16.8 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KFX97337.1 - 0.0046 16.3 0.0 0.037 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 KFX97337.1 - 0.0074 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KFX97337.1 - 0.022 15.0 0.1 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 KFX97337.1 - 0.025 14.7 0.0 0.09 12.9 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 KFX97337.1 - 0.035 13.0 0.1 0.064 12.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 KFX97337.1 - 0.057 12.1 0.0 0.13 10.9 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 KFX97337.1 - 0.073 13.2 0.0 0.26 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFX97337.1 - 0.096 12.3 0.2 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 NTPase DUF87 PF01935.12 KFX97337.1 - 0.11 12.3 4.0 0.11 12.3 0.2 2.8 4 0 0 4 4 3 0 Domain of unknown function DUF87 Aldo_ket_red PF00248.16 KFX97338.1 - 5.2e-59 199.3 0.0 5.9e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2380 PF09533.5 KFX97338.1 - 0.06 12.7 0.1 5 6.4 0.0 2.2 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) GTP_EFTU PF00009.22 KFX97339.1 - 2.6e-21 75.9 0.0 4.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFX97339.1 - 6.4e-14 51.9 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFX97339.1 - 9.8e-09 35.2 1.0 3.6e-08 33.4 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KFX97339.1 - 0.0035 16.8 0.3 0.49 9.8 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KFX97339.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX97339.1 - 0.013 15.9 0.0 0.054 13.9 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein LSM PF01423.17 KFX97340.1 - 1.3e-17 63.1 0.2 1.6e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.12 KFX97341.1 - 2.4e-24 86.2 0.0 4.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Abhydro_lipase PF04083.11 KFX97361.1 - 9e-22 76.2 0.1 1.9e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFX97361.1 - 1.2e-15 57.7 0.2 4.3e-15 55.8 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX97361.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX97361.1 - 3.7e-05 23.5 0.0 0.0003 20.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFX97361.1 - 0.00031 20.2 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) RRM_1 PF00076.17 KFX97362.1 - 2.4e-15 55.8 0.0 8.5e-15 54.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97362.1 - 1.5e-11 44.1 0.0 3.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX97362.1 - 3.6e-06 26.7 0.0 7.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4646 PF15496.1 KFX97362.1 - 7.4e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Nup35_RRM_2 PF14605.1 KFX97362.1 - 0.00063 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif OspD PF03207.8 KFX97362.1 - 0.0098 15.0 0.6 0.015 14.4 0.4 1.2 1 0 0 1 1 1 1 Borrelia outer surface protein D (OspD) DUF148 PF02520.12 KFX97362.1 - 0.13 12.0 0.7 0.31 10.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 Methyltransf_3 PF01596.12 KFX97363.1 - 2.4e-38 131.2 0.0 3.8e-38 130.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KFX97363.1 - 2.7e-13 49.7 0.0 3.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX97363.1 - 1.6e-11 44.1 0.0 2.1e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KFX97363.1 - 2.8e-11 44.1 0.0 1.2e-10 42.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97363.1 - 7.9e-10 39.3 0.0 1.6e-09 38.3 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97363.1 - 7.9e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97363.1 - 2.8e-06 27.5 0.0 5.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KFX97363.1 - 4.5e-05 23.0 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 KFX97363.1 - 0.00019 20.6 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFX97363.1 - 0.00054 19.3 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KFX97363.1 - 0.0006 20.2 0.0 0.0027 18.1 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFX97363.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 KFX97363.1 - 0.0025 18.2 0.1 0.0065 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.12 KFX97363.1 - 0.018 13.9 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.12 KFX97363.1 - 0.054 12.5 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_30 PF05430.6 KFX97363.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase ISN1 PF06437.6 KFX97364.1 - 6.9e-185 614.5 0.0 7.8e-185 614.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pex16 PF08610.5 KFX97365.1 - 4.5e-100 334.9 0.0 4.5e-100 334.9 0.0 1.3 2 0 0 2 2 2 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.15 KFX97365.1 - 0.0017 18.6 0.6 0.92 9.8 0.0 2.3 2 0 0 2 2 2 2 Na+ dependent nucleoside transporter N-terminus DUF3895 PF13034.1 KFX97365.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Ery_res_leader1 PF08051.6 KFX97365.1 - 0.12 12.0 0.5 0.27 10.9 0.4 1.6 1 0 0 1 1 1 0 Erythromycin resistance leader peptide MFS_1 PF07690.11 KFX97366.1 - 4.8e-40 137.3 38.4 2e-38 132.0 15.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97366.1 - 1e-05 24.3 8.8 1e-05 24.3 6.1 2.6 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX97366.1 - 1.6e-05 23.5 3.1 1.6e-05 23.5 2.1 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KFX97366.1 - 0.00036 19.3 1.5 0.00071 18.3 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) F-box PF00646.28 KFX97367.1 - 7.3e-08 31.8 0.9 1.4e-07 30.9 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX97367.1 - 2.5e-05 23.8 1.0 4.5e-05 23.0 0.7 1.5 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.18 KFX97368.1 - 1e-64 218.2 0.2 1.8e-64 217.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain BAR PF03114.13 KFX97368.1 - 5.4e-14 52.2 0.1 1.2e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFX97368.1 - 1.6e-13 49.9 0.2 4.1e-13 48.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFX97368.1 - 4.4e-12 45.2 0.1 8.7e-12 44.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFX97368.1 - 7.5e-10 38.1 0.1 1.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Helicase_C PF00271.26 KFX97368.1 - 7.6e-10 38.5 0.0 1.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KFX97368.1 - 2.2e-07 30.4 3.2 3.8e-07 29.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX97368.1 - 6.4e-07 29.2 5.7 1.2e-06 28.3 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX97368.1 - 1e-06 28.2 5.5 2.3e-06 27.1 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX97368.1 - 2.6e-06 27.1 4.8 4.5e-06 26.3 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFX97368.1 - 0.00016 21.3 4.3 0.00029 20.4 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 KFX97368.1 - 0.0013 18.2 0.0 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 KFX97368.1 - 0.0018 17.9 2.5 0.0041 16.8 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX97368.1 - 0.0024 17.6 7.2 0.0062 16.3 5.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Fer2 PF00111.22 KFX97368.1 - 0.049 13.3 0.5 0.14 11.9 0.3 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_4 PF14570.1 KFX97368.1 - 0.16 11.5 4.0 0.38 10.3 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 KFX97368.1 - 0.99 8.9 2.8 2 7.9 1.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4449 PF14613.1 KFX97369.1 - 8.7e-09 35.5 1.0 3.5e-08 33.5 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 KFX97369.1 - 0.00051 19.8 0.0 0.0022 17.8 0.0 2.1 1 0 0 1 1 1 1 Tricorn protease C1 domain DUF1828 PF08861.5 KFX97369.1 - 0.0027 17.3 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF1828 CPSase_L_D2 PF02786.12 KFX97370.1 - 1.8e-73 246.2 0.0 2.9e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFX97370.1 - 1.3e-34 118.3 0.0 2.8e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFX97370.1 - 2.8e-33 114.2 0.0 6.7e-33 113.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX97370.1 - 2e-17 63.5 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFX97370.1 - 3.2e-14 52.3 0.7 1.1e-13 50.6 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFX97370.1 - 2.1e-10 39.8 0.0 4.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX97370.1 - 9.5e-09 34.9 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.14 KFX97370.1 - 0.00072 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.1 KFX97370.1 - 0.0026 17.4 0.0 2.6 7.7 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KFX97370.1 - 0.0041 17.0 0.0 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFX97370.1 - 0.047 13.1 0.0 0.13 11.6 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Ank_5 PF13857.1 KFX97370.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Mito_carr PF00153.22 KFX97372.1 - 4.3e-47 157.7 6.9 1.5e-18 66.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HA2 PF04408.18 KFX97376.1 - 2.2e-15 56.5 0.1 5.2e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFX97376.1 - 1.3e-14 53.9 0.0 3.8e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFX97376.1 - 2.9e-11 43.0 0.0 7.2e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX97376.1 - 1.5e-06 27.7 0.0 1.5e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX97376.1 - 0.0018 18.3 0.0 0.0053 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFX97376.1 - 0.0024 17.3 0.0 0.0068 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KFX97376.1 - 0.027 13.5 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KFX97376.1 - 0.061 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KFX97376.1 - 0.18 10.6 0.1 0.43 9.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PEPCK_ATP PF01293.15 KFX97378.1 - 4.9e-42 144.0 0.0 5.7e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF1996 PF09362.5 KFX97382.1 - 1.5e-38 132.8 0.0 1.9e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AICARFT_IMPCHas PF01808.13 KFX97386.1 - 5.1e-68 229.4 0.0 6.3e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Glyco_hydro_18 PF00704.23 KFX97388.1 - 4.8e-52 177.5 0.4 8.4e-52 176.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFX97388.1 - 2.4e-06 27.3 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 KFX97388.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) LysM PF01476.15 KFX97389.1 - 2.6e-12 46.4 0.1 0.0003 20.6 0.0 3.9 4 0 0 4 4 4 3 LysM domain PAN_4 PF14295.1 KFX97389.1 - 2.7e-07 30.1 4.5 0.00017 21.1 0.2 3.4 4 0 0 4 4 4 2 PAN domain PAN_2 PF08276.6 KFX97389.1 - 0.00031 20.5 2.8 0.25 11.2 0.2 2.9 2 0 0 2 2 2 2 PAN-like domain PAN_3 PF08277.7 KFX97389.1 - 0.012 15.2 11.3 0.27 10.8 0.1 3.3 3 0 0 3 3 3 0 PAN-like domain Atg31 PF09795.4 KFX97390.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 31 Aldo_ket_red PF00248.16 KFX97394.1 - 2.4e-57 193.9 0.0 2.8e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CCER1 PF15482.1 KFX97395.1 - 0.0079 15.8 2.6 0.21 11.2 0.1 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing glutamate-rich protein family 1 DUF3824 PF12868.2 KFX97395.1 - 0.0087 16.9 0.2 0.022 15.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) Glycophorin_A PF01102.13 KFX97395.1 - 0.0089 15.7 0.1 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A RGS PF00615.14 KFX97399.1 - 3.2e-33 114.3 0.0 7e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KFX97399.1 - 1.1e-20 73.0 0.1 2.7e-16 59.0 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF913 PF06025.7 KFX97402.1 - 0.18 10.5 0.0 0.44 9.2 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PIG-X PF08320.7 KFX97403.1 - 5.5e-55 185.8 0.0 1.1e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 DUF221 PF02714.10 KFX97411.1 - 4.8e-104 347.7 24.1 4.8e-104 347.7 16.7 2.5 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFX97411.1 - 1.5e-41 141.6 0.0 1.5e-41 141.6 0.0 3.6 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFX97411.1 - 1.1e-16 60.4 0.0 2.5e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFX97411.1 - 4.7e-09 36.6 6.7 0.0015 19.0 2.9 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) Ycf1 PF05758.7 KFX97414.1 - 0.063 10.9 0.5 0.061 11.0 0.3 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 KFX97414.1 - 0.44 10.3 11.3 0.87 9.3 7.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PcfJ PF14284.1 KFX97414.1 - 3.5 7.1 8.3 6.4 6.2 5.8 1.4 1 0 0 1 1 1 0 PcfJ-like protein SKN1 PF03935.10 KFX97415.1 - 1.8e-224 745.5 0.3 2.1e-224 745.3 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CHD5 PF04420.9 KFX97417.1 - 1.8e-13 50.4 0.2 2.7e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.17 KFX97418.1 - 1.9e-07 30.1 19.6 0.0014 17.9 0.7 5.0 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat Asp PF00026.18 KFX97420.1 - 1.3e-67 228.3 4.2 1.6e-67 228.0 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX97420.1 - 1.2e-07 31.8 0.6 3.1e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX97420.1 - 6.9e-06 26.4 0.1 0.082 13.4 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFX97420.1 - 0.0029 17.1 0.0 0.11 12.0 0.0 2.3 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KFX97420.1 - 0.0084 15.9 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 KFX97420.1 - 0.029 14.2 0.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease RRM_1 PF00076.17 KFX97421.1 - 1e-13 50.6 0.0 3.5e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97421.1 - 1.7e-08 34.3 0.0 3.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX97421.1 - 4e-06 26.5 0.1 1.7e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX97421.1 - 0.037 13.8 0.1 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SMN PF06003.7 KFX97422.1 - 3.8e-07 29.4 5.8 9.9e-05 21.5 0.5 2.2 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) Copper-bind PF00127.15 KFX97423.1 - 0.0053 16.9 0.5 0.015 15.5 0.3 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 KFX97423.1 - 0.034 13.9 0.8 0.19 11.5 0.5 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Syndecan PF01034.15 KFX97424.1 - 0.019 14.5 0.3 0.049 13.2 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain Ecl1 PF12855.2 KFX97431.1 - 1.7e-11 43.2 2.7 3e-11 42.3 1.9 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KFX97431.1 - 0.05 13.1 2.1 0.1 12.2 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-FCS PF06467.9 KFX97431.1 - 0.051 13.2 0.8 0.1 12.2 0.6 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF581 PF04570.9 KFX97431.1 - 0.14 11.4 4.8 0.77 9.0 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF581) DNA_pol_lambd_f PF10391.4 KFX97432.1 - 1.6e-21 75.5 0.5 2.8e-21 74.7 0.3 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 KFX97432.1 - 7e-19 67.9 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KFX97432.1 - 8.6e-18 63.7 0.0 1.8e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFX97432.1 - 5.8e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Saccharop_dh PF03435.13 KFX97433.1 - 6.2e-17 61.6 0.0 8.2e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFX97433.1 - 0.0075 16.3 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.14 KFX97434.1 - 1e-39 134.2 8.8 1.1e-39 134.1 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KFX97434.1 - 0.00043 20.0 2.7 0.00066 19.4 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFX97434.1 - 0.0063 15.9 3.4 0.025 14.0 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain Sgf11 PF08209.6 KFX97434.1 - 0.044 13.1 0.3 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Thymidylat_synt PF00303.14 KFX97434.1 - 0.048 12.6 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase zf-BED PF02892.10 KFX97434.1 - 0.067 12.9 4.7 1.5 8.6 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.6 KFX97434.1 - 0.12 12.0 1.2 0.17 11.5 0.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1451 PF07295.6 KFX97434.1 - 0.16 11.7 0.6 0.22 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) CarbpepA_inh PF02977.10 KFX97434.1 - 0.21 11.1 0.3 0.21 11.1 0.2 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Zn-ribbon_8 PF09723.5 KFX97434.1 - 0.4 10.6 4.0 0.6 10.1 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 KFX97434.1 - 0.48 10.8 4.6 0.74 10.2 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX97434.1 - 1.6 9.1 7.5 0.68 10.3 0.5 2.3 1 1 1 2 2 2 0 Zinc-finger double domain PHD PF00628.24 KFX97435.1 - 1.8e-09 37.1 8.2 1.8e-09 37.1 5.7 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KFX97435.1 - 3.4e-09 36.3 2.6 3.4e-09 36.3 1.8 4.0 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFX97435.1 - 1.5e-06 28.1 5.7 1.5e-06 28.1 3.9 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFX97435.1 - 2e-06 27.3 1.4 2e-06 27.3 1.0 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX97435.1 - 5.5e-06 26.0 3.3 5.5e-06 26.0 2.3 3.7 4 1 0 4 4 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX97435.1 - 1e-05 25.4 1.0 1e-05 25.4 0.7 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX97435.1 - 3e-05 23.7 2.0 3e-05 23.7 1.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KFX97435.1 - 0.00023 20.7 4.1 0.00023 20.7 2.8 3.6 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KFX97435.1 - 0.00039 19.7 2.3 0.00041 19.6 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger PHD_2 PF13831.1 KFX97435.1 - 0.0031 16.7 3.6 0.0031 16.7 2.5 2.1 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.1 KFX97435.1 - 0.0089 15.5 3.1 0.012 15.1 0.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 KFX97435.1 - 0.015 14.9 6.6 0.015 14.9 4.6 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 KFX97435.1 - 0.058 13.1 0.3 0.058 13.1 0.2 4.0 4 0 0 4 4 4 0 RING-type zinc-finger FANCL_C PF11793.3 KFX97435.1 - 0.36 10.8 9.9 0.12 12.3 1.4 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-PHD-like PF15446.1 KFX97435.1 - 1.5 8.1 9.6 0.38 10.0 0.2 3.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Prim_Zn_Ribbon PF08273.7 KFX97435.1 - 3.3 7.8 12.5 1 9.4 1.1 2.9 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase CFC PF09443.5 KFX97435.1 - 4.3 7.0 8.2 12 5.5 1.0 2.4 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) DZR PF12773.2 KFX97435.1 - 4.7 7.1 10.4 4.2e+02 0.8 7.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon MRP-L46 PF11788.3 KFX97436.1 - 1.4e-29 102.9 0.1 2.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KFX97436.1 - 0.0036 16.9 0.1 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF737 PF05300.6 KFX97436.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Arf PF00025.16 KFX97437.1 - 1.1e-14 54.0 0.0 5.4e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFX97437.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PRCC PF10253.4 KFX97438.1 - 1.2e-34 120.5 2.9 1.2e-34 120.5 2.0 1.9 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SIN1 PF05422.7 KFX97439.1 - 1.8e-38 132.3 0.0 3.4e-19 68.7 0.0 3.0 2 2 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KFX97439.1 - 0.00062 19.6 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 KFX97439.1 - 0.066 12.9 0.1 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Raf-like Ras-binding domain Glyco_hydro_28 PF00295.12 KFX97455.1 - 6.7e-49 166.5 0.8 9.2e-49 166.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ET PF01684.11 KFX97455.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 ET module ORC6 PF05460.8 KFX97457.1 - 1.5e-46 159.1 1.4 1e-45 156.4 1.0 1.9 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.1 KFX97458.1 - 6.4e-07 28.7 2.5 0.035 13.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFX97458.1 - 1.7e-05 23.7 0.6 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFX97458.1 - 2.3e-05 24.4 4.2 0.004 17.2 0.7 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KFX97458.1 - 2.8e-05 23.2 0.8 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KFX97458.1 - 5.2e-05 22.7 0.9 0.00011 21.7 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain pair Metallophos PF00149.23 KFX97459.1 - 4.3e-37 127.4 0.0 4.9e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Nop14 PF04147.7 KFX97463.1 - 0.00011 20.2 10.5 0.00014 19.9 7.3 1.1 1 0 0 1 1 1 1 Nop14-like family JmjC PF02373.17 KFX97465.1 - 1.6e-39 134.6 0.3 4.3e-39 133.2 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KFX97465.1 - 5e-19 68.3 3.5 9e-19 67.5 2.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFX97465.1 - 5.5e-16 58.4 2.2 1.1e-15 57.4 1.5 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 KFX97465.1 - 9.9e-15 53.7 0.3 2.3e-14 52.6 0.2 1.7 1 0 0 1 1 1 1 jmjN domain Sigma70_ner PF04546.8 KFX97466.1 - 0.76 9.3 5.5 0.84 9.2 1.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region WD40 PF00400.27 KFX97467.1 - 7.7e-22 76.3 13.8 0.00014 21.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KFX97467.1 - 0.01 14.0 1.3 1.2 7.1 0.0 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KFX97467.1 - 0.098 12.9 0.8 2.9 8.2 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.27 KFX97468.1 - 3.8e-23 80.4 6.8 8.6e-08 31.7 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3639 PF12341.3 KFX97468.1 - 2e-10 40.4 1.7 2e-10 40.4 1.2 3.4 5 0 0 5 5 5 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KFX97468.1 - 2e-06 26.8 0.0 4.5e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KFX97468.1 - 5.7e-05 22.9 0.1 0.0067 16.1 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFX97468.1 - 0.0036 15.1 0.0 0.0099 13.7 0.0 1.6 1 1 0 1 1 1 1 IKI3 family DNA_pol_alpha_N PF12254.3 KFX97468.1 - 0.061 13.1 3.1 0.16 11.8 2.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Apc4_WD40 PF12894.2 KFX97468.1 - 0.064 12.7 0.0 52 3.4 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.17 KFX97469.1 - 1.3e-65 219.7 0.5 1.5e-65 219.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX97469.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX97469.1 - 2.4e-16 59.4 0.1 2.9e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX97469.1 - 2e-05 23.8 0.1 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX97469.1 - 2.8e-05 23.6 0.2 6e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX97469.1 - 5.9e-05 23.0 0.1 9.3e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX97469.1 - 0.00038 19.7 0.0 0.00055 19.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 KFX97469.1 - 0.00049 20.3 0.1 0.094 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX97469.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 KFX97469.1 - 0.003 16.8 0.0 0.02 14.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX97469.1 - 0.0088 15.2 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX97469.1 - 0.016 15.2 0.1 0.065 13.2 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KFX97469.1 - 0.021 14.7 0.2 0.067 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX97469.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KFX97469.1 - 0.054 13.2 0.1 0.096 12.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KFX97469.1 - 0.063 13.5 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 KFX97469.1 - 0.084 11.8 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KFX97469.1 - 0.089 12.2 0.0 0.93 8.9 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation XRN_N PF03159.13 KFX97475.1 - 1.4e-106 355.2 0.1 3.7e-106 353.8 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.14 KFX97475.1 - 6.1e-46 156.5 0.1 1.1e-45 155.6 0.1 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KFX97475.1 - 2.8e-08 33.8 0.1 7.8e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-CCHC PF00098.18 KFX97475.1 - 0.31 11.0 2.8 0.71 9.9 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.9 KFX97476.1 - 4.2e-109 364.0 0.0 7.1e-109 363.3 0.0 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KFX97476.1 - 1.7e-05 24.7 31.3 1.7e-05 24.7 21.7 3.3 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.9 KFX97476.1 - 0.23 10.8 13.5 0.22 10.9 0.1 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain tRNA-synt_1 PF00133.17 KFX97477.1 - 1e-219 730.5 0.0 1.4e-219 730.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFX97477.1 - 3.3e-23 82.1 0.0 1.2e-22 80.2 0.0 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFX97477.1 - 6.3e-19 67.8 0.2 5.8e-08 31.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KFX97477.1 - 0.018 14.1 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Rav1p_C PF12234.3 KFX97478.1 - 1.4e-265 882.3 0.1 1.9e-265 881.9 0.1 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Sfi1 PF08457.5 KFX97478.1 - 1.2e-112 377.2 67.7 1.2e-112 377.2 46.9 2.0 1 1 1 2 2 2 1 Sfi1 spindle body protein WD40 PF00400.27 KFX97478.1 - 1.2e-05 25.0 0.6 0.049 13.5 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat OPT PF03169.10 KFX97479.1 - 2.6e-154 515.0 26.8 3e-154 514.8 18.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gly-zipper_Omp PF13488.1 KFX97479.1 - 0.11 12.1 5.5 0.34 10.5 0.1 3.4 3 0 0 3 3 3 0 Glycine zipper Methyltransf_31 PF13847.1 KFX97480.1 - 1.9e-12 47.0 0.0 3.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX97480.1 - 7.7e-12 44.9 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KFX97480.1 - 3.6e-11 43.6 0.1 1.1e-10 42.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97480.1 - 3.8e-10 40.1 0.0 1.2e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97480.1 - 1.9e-09 37.5 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX97480.1 - 4.5e-07 29.4 0.1 7.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFX97480.1 - 6.6e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97480.1 - 6.4e-06 26.4 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX97480.1 - 3.4e-05 23.0 0.1 0.00037 19.6 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 KFX97480.1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 KFX97480.1 - 0.00034 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 KFX97480.1 - 0.00069 18.4 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 KFX97480.1 - 0.0013 17.7 0.0 0.0032 16.4 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 KFX97480.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX97480.1 - 0.0018 18.3 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KFX97480.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KFX97480.1 - 0.004 16.2 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 KFX97480.1 - 0.0057 16.2 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 WD40_alt PF14077.1 KFX97480.1 - 0.021 14.4 0.4 0.042 13.4 0.3 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif TehB PF03848.9 KFX97480.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 KFX97480.1 - 0.06 14.1 0.0 0.31 11.8 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KFX97480.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Packaging_FI PF14000.1 KFX97480.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.7 2 0 0 2 2 1 0 DNA packaging protein FI Mo25 PF08569.6 KFX97481.1 - 2.4e-123 411.4 0.0 4.5e-123 410.5 0.0 1.5 1 0 0 1 1 1 1 Mo25-like SWIB PF02201.13 KFX97481.1 - 8.6e-12 44.5 0.0 1.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Nucleoplasmin PF03066.10 KFX97481.1 - 0.00053 19.5 1.4 0.001 18.5 1.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 KFX97481.1 - 0.11 12.7 6.0 0.26 11.5 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 KFX97481.1 - 0.9 8.7 5.2 1.4 8.0 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 KFX97481.1 - 2.7 8.3 11.2 0.096 12.9 3.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 KFX97484.1 - 5e-67 225.7 0.0 6.6e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97484.1 - 7.4e-34 116.9 0.0 1.2e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX97484.1 - 9.7e-05 21.4 0.0 0.0006 18.8 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFX97484.1 - 0.00057 19.0 0.0 0.00096 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX97484.1 - 0.0039 16.9 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFX97484.1 - 0.11 11.2 0.4 3.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Rif1_N PF12231.3 KFX97486.1 - 5.7e-116 387.5 0.0 8.1e-116 387.0 0.0 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal RPN7 PF10602.4 KFX97500.1 - 2.6e-58 196.3 0.4 4e-58 195.7 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFX97500.1 - 1.6e-13 50.8 0.0 3.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 KFX97500.1 - 0.093 13.4 0.2 1.3 9.9 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2201_N PF13203.1 KFX97500.1 - 0.36 9.9 2.7 0.54 9.3 1.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Lactamase_B_2 PF12706.2 KFX97502.1 - 7.1e-32 110.5 0.0 8.5e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFX97502.1 - 0.0065 16.1 0.1 0.012 15.2 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFX97502.1 - 0.035 13.7 2.6 0.12 12.0 1.8 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Prok-JAB PF14464.1 KFX97502.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Fungal_trans PF04082.13 KFX97510.1 - 1.1e-15 57.2 0.1 1.9e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain rRNA_processing PF08524.6 KFX97510.1 - 0.065 13.0 0.9 0.11 12.3 0.6 1.2 1 0 0 1 1 1 0 rRNA processing ABC2_membrane PF01061.19 KFX97511.1 - 5.4e-88 293.6 56.1 1.3e-47 161.7 15.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFX97511.1 - 1.3e-40 138.8 0.0 3.4e-19 69.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFX97511.1 - 1.5e-24 85.5 6.7 7.7e-24 83.3 0.0 3.0 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KFX97511.1 - 1.6e-11 43.8 32.3 7.8e-07 28.4 10.3 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_22 PF13401.1 KFX97511.1 - 4.7e-06 26.7 0.2 0.087 12.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KFX97511.1 - 5.6e-06 25.9 0.1 0.011 15.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX97511.1 - 0.0002 21.4 0.4 0.14 12.1 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain cobW PF02492.14 KFX97511.1 - 0.0003 20.2 0.5 0.32 10.4 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KFX97511.1 - 0.00036 21.3 0.0 1.2 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KFX97511.1 - 0.00041 20.3 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFX97511.1 - 0.00065 18.9 0.0 0.0051 16.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFX97511.1 - 0.00065 19.5 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KFX97511.1 - 0.0012 18.8 0.1 0.003 17.6 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 KFX97511.1 - 0.0014 18.0 0.6 0.081 12.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KFX97511.1 - 0.0029 17.2 0.5 2.5 7.7 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KFX97511.1 - 0.003 17.8 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX97511.1 - 0.004 16.8 0.5 1.4 8.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KFX97511.1 - 0.006 16.3 0.0 2.1 7.9 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase PduV-EutP PF10662.4 KFX97511.1 - 0.0092 15.4 0.8 1.6 8.2 0.2 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KFX97511.1 - 0.011 15.7 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KFX97511.1 - 0.031 14.4 0.0 7.5 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 KFX97511.1 - 0.085 13.3 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 KFX97511.1 - 0.1 12.2 0.7 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KFX97511.1 - 0.14 10.9 0.0 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Sec8_exocyst PF04048.9 KFX97512.1 - 5.7e-49 165.3 2.6 1.1e-48 164.4 1.8 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KFX97512.1 - 5.8e-12 45.1 3.6 1.1e-11 44.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 KFX97512.1 - 0.0068 16.2 2.7 0.0072 16.1 0.3 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.1 KFX97512.1 - 0.012 15.4 0.2 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 Vps51 PF08700.6 KFX97512.1 - 0.072 12.9 0.6 0.3 10.9 0.4 2.1 1 0 0 1 1 1 0 Vps51/Vps67 DUF3829 PF12889.2 KFX97512.1 - 0.12 11.5 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) SMI1_KNR4 PF09346.5 KFX97513.1 - 1e-33 116.0 0.0 1.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.6 KFX97514.1 - 2.1e-63 212.5 2.7 2.3e-63 212.3 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RF-1 PF00472.15 KFX97515.1 - 1e-24 86.5 0.4 1.4e-24 86.1 0.2 1.1 1 0 0 1 1 1 1 RF-1 domain Cwf_Cwc_15 PF04889.7 KFX97515.1 - 0.025 14.3 0.4 0.029 14.0 0.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3317 PF11779.3 KFX97516.1 - 4.4e-08 32.4 8.6 2.4e-05 23.6 6.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) CENP-I PF07778.6 KFX97517.1 - 1.6e-89 300.4 0.0 1.2e-55 188.7 0.0 2.1 2 0 0 2 2 2 2 Mis6 EF-hand_2 PF09068.6 KFX97517.1 - 0.073 13.1 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 EF hand TIR PF01582.15 KFX97518.1 - 0.051 13.0 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 TIR domain Saccharop_dh PF03435.13 KFX97519.1 - 3.7e-131 437.6 0.0 4.1e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFX97519.1 - 3.5e-08 33.6 0.2 5.4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KFX97519.1 - 0.00013 22.0 1.5 0.00021 21.3 1.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 KFX97519.1 - 0.00039 19.8 2.5 0.0012 18.1 0.7 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 KFX97519.1 - 0.0032 17.9 0.5 0.0063 17.0 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KFX97519.1 - 0.0084 16.4 1.1 0.015 15.6 0.8 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFX97519.1 - 0.023 14.9 0.3 0.045 14.0 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 KFX97519.1 - 0.095 11.9 0.6 0.17 11.0 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family USP7_C2 PF14533.1 KFX97519.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal TRAPPC9-Trs120 PF08626.6 KFX97521.1 - 1.1e-150 503.3 0.0 7.2e-150 500.6 0.0 2.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 KFX97521.1 - 0.29 11.2 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 CARDB DUF2404 PF10296.4 KFX97522.1 - 6e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RtcB PF01139.12 KFX97522.1 - 0.1 11.5 0.2 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB CDP-OH_P_transf PF01066.16 KFX97523.1 - 9.3e-17 61.2 6.2 1.7e-16 60.3 4.3 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase RICTOR_V PF14668.1 KFX97523.1 - 0.11 12.4 0.3 4.8 7.1 0.0 3.0 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Tyr-DNA_phospho PF06087.7 KFX97524.1 - 2.6e-74 250.4 0.0 3.6e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFX97524.1 - 9.3e-05 22.1 0.0 0.02 14.6 0.0 2.7 3 0 0 3 3 3 2 PLD-like domain UIM PF02809.15 KFX97524.1 - 0.0085 15.5 1.9 0.0085 15.5 1.3 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif IPPT PF01715.12 KFX97525.1 - 9.4e-54 182.0 0.3 5.6e-53 179.5 0.2 2.1 1 1 0 1 1 1 1 IPP transferase IPT PF01745.11 KFX97525.1 - 0.00011 21.4 0.1 0.00026 20.2 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.2 KFX97525.1 - 0.00017 21.6 0.2 0.00032 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_33 PF13671.1 KFX97525.1 - 0.0015 18.4 0.1 0.073 12.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX97525.1 - 0.0024 18.6 0.2 0.0055 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFX97525.1 - 0.0099 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX97525.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KFX97525.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter zf-C2H2_jaz PF12171.3 KFX97525.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.1 KFX97525.1 - 0.034 14.4 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 KFX97525.1 - 0.035 13.3 0.0 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 KFX97525.1 - 0.081 13.0 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pex2_Pex12 PF04757.9 KFX97525.1 - 0.099 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region SecY PF00344.15 KFX97526.1 - 2.3e-96 322.7 12.3 2.9e-96 322.4 8.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFX97526.1 - 1e-18 66.5 0.3 7.8e-18 63.6 0.2 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p ABC_tran PF00005.22 KFX97527.1 - 1.3e-50 171.2 0.0 1.2e-28 100.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX97527.1 - 6.9e-46 156.8 25.7 7.4e-26 91.1 5.2 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KFX97527.1 - 3.7e-09 36.9 2.2 0.1 12.5 0.0 4.7 5 0 0 5 5 5 2 AAA domain SMC_N PF02463.14 KFX97527.1 - 9.8e-09 34.7 0.3 0.0015 17.7 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX97527.1 - 6e-06 26.7 4.1 0.00054 20.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KFX97527.1 - 4.4e-05 22.9 0.0 0.038 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX97527.1 - 5.2e-05 22.4 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX97527.1 - 6.3e-05 22.4 0.2 0.24 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFX97527.1 - 7.6e-05 22.6 0.3 0.19 11.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KFX97527.1 - 0.00011 23.0 0.3 0.36 11.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFX97527.1 - 0.00028 21.0 0.0 4.8 7.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFX97527.1 - 0.00033 19.8 2.0 0.077 12.0 0.1 2.9 3 0 0 3 3 3 1 Zeta toxin DUF87 PF01935.12 KFX97527.1 - 0.00036 20.4 1.3 0.029 14.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KFX97527.1 - 0.00045 20.7 0.2 1.3 9.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 KFX97527.1 - 0.00083 18.3 0.1 0.025 13.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 KFX97527.1 - 0.00089 19.2 0.4 1.5 8.7 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFX97527.1 - 0.001 19.3 0.9 0.6 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KFX97527.1 - 0.0019 17.6 0.1 1.5 8.1 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain HemX PF04375.9 KFX97527.1 - 0.0023 16.6 0.4 0.004 15.8 0.3 1.3 1 0 0 1 1 1 1 HemX MobB PF03205.9 KFX97527.1 - 0.0046 16.6 0.2 1.9 8.1 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KFX97527.1 - 0.011 15.2 0.1 3.4 7.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KFX97527.1 - 0.015 15.5 0.0 1.8 8.7 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFX97527.1 - 0.017 14.5 0.1 6.2 6.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 KFX97527.1 - 0.071 12.9 0.0 4 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Wzy_C PF04932.10 KFX97527.1 - 0.12 12.1 11.0 0.028 14.2 1.6 3.5 3 1 1 4 4 4 0 O-Antigen ligase ResIII PF04851.10 KFX97527.1 - 0.16 11.8 0.2 8.3 6.1 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit cobW PF02492.14 KFX97527.1 - 0.63 9.4 2.5 2 7.8 0.2 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain CaATP_NAI PF12515.3 KFX97528.1 - 0.17 11.4 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain NDUFA12 PF05071.11 KFX97529.1 - 9.7e-27 93.4 2.3 1.2e-26 93.1 1.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 KFX97530.1 - 0.0095 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 PLD-like domain Glyco_hydro_76 PF03663.9 KFX97545.1 - 6.8e-132 440.3 13.7 1.2e-131 439.5 9.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ORC4_C PF14629.1 KFX97545.1 - 3.3e-53 180.1 0.0 5.5e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KFX97545.1 - 2.7e-18 66.6 0.5 2.7e-18 66.6 0.4 2.3 2 1 0 2 2 1 1 AAA ATPase domain PHD_2 PF13831.1 KFX97545.1 - 2.3e-11 42.8 2.2 4.5e-11 41.8 1.5 1.5 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 KFX97545.1 - 2.9e-10 40.3 0.0 6.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PHD PF00628.24 KFX97545.1 - 7.8e-10 38.2 6.9 1.4e-09 37.5 4.8 1.4 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.7 KFX97545.1 - 7.9e-08 32.1 0.1 2.4e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 KFX97545.1 - 6.4e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KFX97545.1 - 0.00036 19.6 0.0 0.00055 19.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 KFX97545.1 - 0.00041 20.1 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KFX97545.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFX97545.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MobB PF03205.9 KFX97545.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KFX97545.1 - 0.0017 17.8 0.2 0.75 9.1 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KFX97545.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.17 KFX97545.1 - 0.002 17.0 0.1 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 KFX97545.1 - 0.0024 17.5 0.0 0.0068 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX97545.1 - 0.0032 18.2 0.0 0.029 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFX97545.1 - 0.0035 16.8 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KFX97545.1 - 0.0047 16.5 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein C1_1 PF00130.17 KFX97545.1 - 0.0052 16.4 0.9 0.0052 16.4 0.6 1.6 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_33 PF13671.1 KFX97545.1 - 0.007 16.2 0.1 0.024 14.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KFX97545.1 - 0.0096 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KFX97545.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Miro PF08477.8 KFX97545.1 - 0.021 15.3 0.0 0.052 14.0 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein cobW PF02492.14 KFX97545.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KFX97545.1 - 0.048 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFX97545.1 - 0.052 13.2 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 NTPase PIF1 PF05970.9 KFX97545.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.1 KFX97545.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FYVE_2 PF02318.11 KFX97545.1 - 0.11 12.4 1.1 0.22 11.4 0.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger AAA_5 PF07728.9 KFX97545.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KFX97545.1 - 0.12 11.7 0.0 0.83 9.0 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KFX97545.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 KFX97545.1 - 0.2 11.1 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CUE PF02845.11 KFX97547.1 - 1.1e-12 47.1 0.0 1.7e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Kinesin PF00225.18 KFX97550.1 - 1.2e-93 313.5 0.0 1.9e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain IncA PF04156.9 KFX97550.1 - 0.34 10.4 3.9 1.2 8.6 2.8 1.8 2 0 0 2 2 2 0 IncA protein BBP1_C PF15272.1 KFX97550.1 - 0.4 10.1 5.4 1.2 8.6 2.3 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal NARP1 PF12569.3 KFX97551.1 - 0.035 12.8 2.6 0.046 12.4 1.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3824 PF12868.2 KFX97551.1 - 0.39 11.6 5.7 0.81 10.6 3.9 1.5 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) PAT1 PF09770.4 KFX97551.1 - 1.7 6.7 22.0 2.1 6.5 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sod_Cu PF00080.15 KFX97552.1 - 8.6e-20 71.3 2.1 1.3e-19 70.7 1.5 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) LSM PF01423.17 KFX97553.1 - 4.8e-20 70.8 0.0 5.4e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFX97553.1 - 0.039 13.8 0.0 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain NHL PF01436.16 KFX97554.1 - 1.5e-05 24.7 0.0 0.11 12.4 0.0 4.0 4 0 0 4 4 4 2 NHL repeat Gmad1 PF10647.4 KFX97554.1 - 0.01 15.2 0.1 0.027 13.8 0.1 1.6 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Lactonase PF10282.4 KFX97554.1 - 0.028 13.4 0.0 1.3 8.0 0.0 2.5 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller RhoGAP PF00620.22 KFX97555.1 - 6.9e-35 119.9 0.0 1.3e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KFX97555.1 - 6.9e-33 112.5 39.9 3e-12 46.3 5.0 5.0 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.7 KFX97555.1 - 6.1 6.3 6.5 0.34 10.3 0.1 2.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain UQ_con PF00179.21 KFX97556.1 - 4.2e-41 139.6 0.0 3.1e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 KFX97556.1 - 0.002 17.9 0.0 0.14 12.0 0.0 2.5 1 1 1 2 2 2 1 RWD domain UEV PF05743.8 KFX97556.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain FAM60A PF15396.1 KFX97557.1 - 2.9 7.5 5.4 4.4 7.0 3.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BTAD PF03704.12 KFX97577.1 - 0.038 14.2 0.1 0.049 13.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial transcriptional activator domain ABC2_membrane PF01061.19 KFX97587.1 - 3.9e-28 98.0 32.5 5.9e-28 97.4 22.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFX97587.1 - 2.2e-25 89.5 0.0 2.2e-25 89.5 0.0 2.1 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 KFX97587.1 - 2.9e-06 27.4 0.0 0.018 15.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX97587.1 - 7.2e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFX97587.1 - 7.9e-05 21.8 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX97587.1 - 0.00012 21.5 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFX97587.1 - 0.00015 21.9 0.0 0.00058 20.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX97587.1 - 0.00066 19.8 0.0 0.003 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain DDE_1 PF03184.14 KFX97587.1 - 0.0033 16.5 0.0 0.0068 15.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_19 PF13245.1 KFX97587.1 - 0.007 16.0 0.1 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KFX97587.1 - 0.0081 16.1 0.0 0.034 14.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.14 KFX97587.1 - 0.0088 15.2 0.0 0.028 13.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFX97587.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KFX97587.1 - 0.03 15.1 0.0 0.081 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KFX97587.1 - 0.035 13.6 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 KFX97587.1 - 0.037 13.4 0.2 0.1 12.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 KFX97587.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 KFX97587.1 - 0.055 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KFX97587.1 - 0.055 13.3 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 KFX97587.1 - 0.065 13.5 0.2 0.29 11.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KFX97587.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KFX97587.1 - 0.069 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KFX97587.1 - 0.095 12.3 0.7 0.21 11.2 0.0 1.9 2 0 0 2 2 1 0 Archaeal ATPase AAA_33 PF13671.1 KFX97587.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF3886 PF13025.1 KFX97587.1 - 4.8 7.2 12.5 3.2 7.7 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) 2OG-FeII_Oxy PF03171.15 KFX97609.1 - 4.5e-14 52.5 0.0 6.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFX97609.1 - 3.5e-06 27.5 0.0 6.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans_2 PF11951.3 KFX97610.1 - 8.5e-09 34.4 0.1 9.5e-07 27.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 KFX97611.1 - 3.9e-11 42.6 0.0 1.1e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX97611.1 - 3e-10 41.0 0.0 7e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX97611.1 - 1.8e-05 24.4 1.8 0.00094 18.9 0.9 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFX97611.1 - 0.0094 15.9 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFX97611.1 - 0.011 15.5 0.2 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 KFX97612.1 - 1.7e-31 109.8 0.0 2.9e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX97612.1 - 1.7e-18 67.0 0.0 3.6e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3632 PF12311.3 KFX97612.1 - 1.2e-13 51.2 0.0 1.9e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Abhydrolase_5 PF12695.2 KFX97612.1 - 1.4e-09 37.8 0.0 5.3e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX97612.1 - 0.00061 19.5 0.0 0.004 16.9 0.0 2.4 1 1 1 2 2 2 1 Putative lysophospholipase DUF1057 PF06342.7 KFX97612.1 - 0.0011 17.7 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Phage_Cox PF10743.4 KFX97612.1 - 0.31 11.0 1.4 35 4.4 0.0 3.0 3 0 0 3 3 3 0 Regulatory phage protein cox E1-E2_ATPase PF00122.15 KFX97613.1 - 2.7e-46 157.4 4.6 5.2e-46 156.5 3.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX97613.1 - 6.6e-43 146.3 5.1 6.6e-43 146.3 3.6 3.6 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX97613.1 - 1.5e-30 107.2 0.0 5e-30 105.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX97613.1 - 1.9e-18 66.1 0.0 4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFX97613.1 - 1.1e-14 55.1 0.0 2.7e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX97613.1 - 9.9e-10 37.7 0.0 2.6e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFX97613.1 - 0.00066 19.3 0.2 0.0016 18.0 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 KFX97614.1 - 2.8e-80 261.5 14.9 3.1e-09 36.3 0.0 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KFX97614.1 - 1.7e-46 157.3 0.1 2.7e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KFX97614.1 - 2.5e-09 35.8 9.8 0.039 12.1 0.0 5.8 2 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX97614.1 - 1e-06 27.8 2.9 0.41 9.3 0.0 5.6 5 1 1 6 6 6 2 Nup133 N terminal like DUF4260 PF14079.1 KFX97615.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) KAR9 PF08580.5 KFX97615.1 - 0.88 7.7 3.5 1.2 7.3 2.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1237 PF06824.6 KFX97616.1 - 1.8e-180 600.1 0.0 2.2e-180 599.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) MFS_1 PF07690.11 KFX97616.1 - 8.1e-29 100.4 48.9 3.2e-26 91.8 22.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_47 PF01532.15 KFX97617.1 - 4e-137 457.5 0.0 4.7e-137 457.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FMO-like PF00743.14 KFX97618.1 - 7.1e-42 143.2 0.0 3.5e-27 94.7 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX97618.1 - 2.5e-17 63.6 0.2 2.3e-16 60.4 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX97618.1 - 6.6e-13 48.7 0.1 2.3e-10 40.4 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFX97618.1 - 2.2e-12 47.2 0.7 3.9e-10 39.9 0.4 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX97618.1 - 4.8e-11 42.1 1.9 2.3e-08 33.3 0.1 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX97618.1 - 4.7e-09 36.1 0.3 4.4e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX97618.1 - 1.1e-08 34.5 0.1 2.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFX97618.1 - 5.5e-07 28.8 1.0 0.0033 16.3 0.1 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX97618.1 - 5.2e-06 26.7 0.2 0.031 14.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX97618.1 - 0.001 17.6 3.7 0.0033 15.9 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.15 KFX97618.1 - 0.0031 17.6 0.2 0.85 9.7 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 KFX97618.1 - 0.012 14.7 0.0 0.05 12.6 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KFX97618.1 - 0.016 14.2 0.3 0.32 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KFX97618.1 - 0.016 14.1 0.6 1.3 7.8 0.1 2.6 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 KFX97618.1 - 0.024 13.7 0.0 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX97618.1 - 0.026 14.2 0.0 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 KFX97618.1 - 0.039 13.0 1.0 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX97618.1 - 0.082 11.7 1.6 0.38 9.5 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KFX97618.1 - 0.099 11.4 1.5 2.2 7.0 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Malic_M PF03949.10 KFX97618.1 - 0.11 12.0 0.1 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_7 PF13241.1 KFX97618.1 - 0.12 12.6 0.0 30 4.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KFX97618.1 - 0.14 11.7 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyridox_ox_2 PF12900.2 KFX97619.1 - 3.8e-37 127.2 0.0 4.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH PF00443.24 KFX97621.1 - 1.6e-26 92.9 0.0 2.4e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFX97621.1 - 2.4e-11 43.5 0.3 4.4e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFX97621.1 - 0.0028 17.1 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KFX97622.1 - 3.3e-32 109.1 7.7 1e-08 34.7 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFX97622.1 - 0.041 12.6 0.1 0.38 9.4 0.0 2.3 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 KFX97622.1 - 0.045 11.8 0.1 1.1 7.2 0.0 2.5 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nha1_C PF08619.5 KFX97622.1 - 0.13 11.5 10.7 0.2 10.8 7.4 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Proteasome PF00227.21 KFX97623.1 - 2.8e-30 105.0 0.0 3.1e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Viral_DNA_bp PF00747.12 KFX97623.1 - 0.085 10.0 0.0 0.11 9.7 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein Glyco_hydro_3 PF00933.16 KFX97625.1 - 2.9e-89 298.9 0.0 4.4e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX97625.1 - 1.2e-56 191.7 0.1 3.6e-56 190.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX97625.1 - 1.9e-20 72.5 0.0 3.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PAN_2 PF08276.6 KFX97626.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.21 KFX97626.1 - 0.029 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 PAN domain ThiF PF00899.16 KFX97627.1 - 2.9e-37 127.5 0.1 4.9e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 KFX97627.1 - 8.3e-05 22.7 0.1 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 KFX97627.1 - 0.00014 20.9 0.6 0.00042 19.4 0.4 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 KFX97627.1 - 0.011 15.2 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KFX97627.1 - 0.018 15.0 0.2 0.055 13.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.19 KFX97627.1 - 0.023 13.6 0.1 0.038 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFX97627.1 - 0.027 13.8 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KFX97627.1 - 0.046 13.3 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 KFX97627.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 KR domain NAD_Gly3P_dh_N PF01210.18 KFX97627.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KFX97627.1 - 0.15 12.1 0.1 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KFX97629.1 - 1e-10 41.5 0.2 2e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX97629.1 - 8.1e-08 31.5 1.0 1.5e-07 30.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX97629.1 - 2.9e-07 29.7 1.7 1.2e-06 27.7 0.8 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX97629.1 - 4.8e-07 30.1 0.2 1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX97629.1 - 5.2e-07 29.9 0.6 6.7e-05 23.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX97629.1 - 1.8e-06 27.3 3.0 3.8e-06 26.2 2.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX97629.1 - 3.4e-06 27.0 0.1 0.0009 19.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX97629.1 - 1.5e-05 23.6 0.6 2.7e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFX97629.1 - 0.00016 20.8 0.7 0.00028 20.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KFX97629.1 - 0.0012 18.0 0.2 0.0021 17.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 KFX97629.1 - 0.0031 16.4 0.3 2 7.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFX97629.1 - 0.0031 16.4 0.1 0.0046 15.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 KFX97629.1 - 0.0076 15.3 0.0 0.015 14.4 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFX97629.1 - 0.0093 14.9 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein IlvN PF07991.7 KFX97629.1 - 0.055 12.8 0.1 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain B12-binding PF02310.14 KFX97629.1 - 0.086 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain Shikimate_DH PF01488.15 KFX97629.1 - 0.17 11.9 0.1 3.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KFX97629.1 - 0.56 9.6 2.7 1.7 8.0 0.3 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AAA_12 PF13087.1 KFX97630.1 - 1.2e-35 122.7 0.0 3.6e-35 121.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFX97630.1 - 2.4e-25 89.5 0.8 1.3e-24 87.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX97630.1 - 4e-10 39.2 0.0 1.4e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFX97630.1 - 5.4e-10 39.1 0.0 9.7e-08 31.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KFX97630.1 - 1.1e-06 28.3 0.0 0.013 15.0 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KFX97630.1 - 0.0003 20.6 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFX97630.1 - 0.0052 15.8 0.3 0.24 10.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KFX97630.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.24 KFX97630.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase WD40 PF00400.27 KFX97631.1 - 5.5e-17 60.9 7.2 0.00056 19.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 KFX97631.1 - 0.1 12.2 1.3 11 5.7 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KFX97631.1 - 0.11 10.6 0.2 4.1 5.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SelR PF01641.13 KFX97635.1 - 2.3e-49 166.1 0.1 3.2e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KFX97635.1 - 0.003 17.3 2.1 0.31 10.8 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon GFA PF04828.9 KFX97635.1 - 0.0081 16.0 0.2 1.1 9.2 0.0 2.4 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KFX97635.1 - 0.051 13.3 0.5 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 KFX97635.1 - 0.063 12.6 0.8 2.2 7.6 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.9 KFX97635.1 - 0.18 11.8 0.5 0.69 9.9 0.3 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Fungal_trans_2 PF11951.3 KFX97636.1 - 1.5e-29 102.7 1.0 1.8e-29 102.5 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KFX97637.1 - 1.5e-38 132.6 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX97637.1 - 1.1e-05 25.3 0.1 7.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX97637.1 - 6e-05 23.1 0.0 0.0012 18.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX97637.1 - 6.2e-05 22.9 0.0 0.0033 17.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX97637.1 - 0.0012 18.6 0.0 0.043 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX97637.1 - 0.0019 18.5 0.0 0.068 13.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX97637.1 - 0.0056 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 KFX97637.1 - 0.012 14.4 0.3 0.02 13.7 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KFX97637.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX97637.1 - 0.03 14.0 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KFX97637.1 - 0.059 12.2 0.0 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 KFX97637.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KFX97637.1 - 0.074 11.5 0.0 1.9 6.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_6 PF12697.2 KFX97638.1 - 5.1e-27 95.2 0.1 6.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX97638.1 - 9.1e-21 74.4 0.0 1.2e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX97638.1 - 1.2e-12 47.8 0.0 5.3e-12 45.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX97638.1 - 2.6e-05 23.9 0.0 5.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KFX97638.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein HSP70 PF00012.15 KFX97639.1 - 1.1e-265 882.3 13.2 1.2e-265 882.1 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFX97639.1 - 1.6e-16 59.7 1.8 4e-15 55.2 0.1 2.1 1 1 1 2 2 2 2 MreB/Mbl protein Radial_spoke_3 PF06098.6 KFX97639.1 - 0.0029 16.6 1.2 0.0029 16.6 0.8 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 Hydantoinase_A PF01968.13 KFX97639.1 - 0.028 13.5 4.9 0.032 13.3 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KFX97639.1 - 0.051 13.4 4.7 0.33 10.7 0.1 3.4 2 2 0 2 2 2 0 Cell division protein FtsA GTP_EFTU PF00009.22 KFX97640.1 - 7.8e-51 172.1 0.0 1.2e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KFX97640.1 - 1.6e-21 76.1 3.3 3.3e-21 75.1 2.3 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 KFX97640.1 - 1.2e-08 34.8 0.1 3.4e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX97640.1 - 3.1e-08 33.5 0.1 2.4e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KFX97640.1 - 7.6e-08 32.4 0.0 2.5e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 KFX97640.1 - 8.4e-05 23.0 0.1 0.0015 19.0 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KFX97640.1 - 0.027 13.6 0.0 1.9 7.6 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KFX97640.1 - 0.051 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 KFX97640.1 - 0.18 11.0 0.2 1.9 7.7 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Arrestin_C PF02752.17 KFX97641.1 - 1.2e-16 61.0 0.0 7.9e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KFX97641.1 - 9.1e-12 45.0 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KFX97641.1 - 0.0004 19.9 0.0 0.047 13.1 0.0 2.5 2 0 0 2 2 2 2 Arrestin_N terminal like WD40 PF00400.27 KFX97642.1 - 5.6e-20 70.4 11.7 3e-06 26.8 0.4 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.7 KFX97642.1 - 3.8e-05 21.7 0.0 0.00045 18.2 0.0 1.9 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.6 KFX97642.1 - 8.9e-05 22.2 0.0 0.0022 17.7 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KFX97642.1 - 0.023 12.9 0.0 0.071 11.3 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Miro PF08477.8 KFX97643.1 - 1.9e-36 125.1 0.0 4.3e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KFX97643.1 - 5.3e-33 112.6 0.0 9.9e-33 111.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KFX97643.1 - 4e-31 106.1 0.1 7.1e-31 105.3 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KFX97643.1 - 9.2e-26 90.1 0.0 1.1e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KFX97643.1 - 3.7e-09 36.5 0.0 0.00016 21.5 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 KFX97643.1 - 1.4e-08 34.7 0.3 0.00029 20.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFX97643.1 - 2.1e-08 32.8 1.8 0.0061 15.7 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFX97643.1 - 5.8e-07 28.8 2.1 0.032 14.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain Dynamin_N PF00350.18 KFX97643.1 - 9.2e-07 28.8 0.9 0.1 12.3 0.0 3.8 3 1 1 4 4 4 2 Dynamin family AAA_16 PF13191.1 KFX97643.1 - 1.4e-06 28.4 0.0 0.078 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.1 KFX97643.1 - 2.3e-05 23.5 3.6 0.032 13.5 1.2 2.7 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 KFX97643.1 - 2.7e-05 24.3 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFX97643.1 - 0.00013 21.3 0.0 0.099 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_8 PF13833.1 KFX97643.1 - 0.00023 20.7 1.5 0.72 9.5 0.8 2.6 2 0 0 2 2 2 2 EF-hand domain pair AAA_28 PF13521.1 KFX97643.1 - 0.0006 19.8 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFX97643.1 - 0.0013 18.3 0.0 0.075 12.7 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFX97643.1 - 0.0037 17.4 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.22 KFX97643.1 - 0.0041 16.5 0.0 6.4 6.1 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KFX97643.1 - 0.0072 15.7 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFX97643.1 - 0.026 14.2 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KFX97643.1 - 0.026 14.1 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 KFX97643.1 - 0.036 13.7 0.2 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.1 KFX97643.1 - 0.043 13.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFX97643.1 - 0.076 12.4 0.0 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 KFX97643.1 - 0.093 11.6 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFX97643.1 - 0.1 12.8 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF2433 PF10360.4 KFX97644.1 - 1.9e-55 186.7 0.0 3.2e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KFX97644.1 - 0.0078 16.0 0.0 0.019 14.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 KFX97644.1 - 0.16 12.2 12.9 15 5.8 9.0 2.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TFIIA PF03153.8 KFX97644.1 - 2.5 7.9 12.2 3.7 7.3 8.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 KFX97644.1 - 4.2 6.6 19.4 7.4 5.8 13.4 1.3 1 0 0 1 1 1 0 Vta1 like Ubie_methyltran PF01209.13 KFX97645.1 - 1.7e-83 279.2 0.0 2.3e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFX97645.1 - 2.2e-17 63.2 0.0 4.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97645.1 - 1.3e-16 60.5 0.0 1.7e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97645.1 - 1.1e-12 48.1 0.0 2.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97645.1 - 2.1e-11 44.1 0.0 4.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97645.1 - 6.2e-11 42.2 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97645.1 - 1.3e-08 35.3 0.0 2.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97645.1 - 2.2e-05 24.4 0.0 5.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFX97645.1 - 0.00077 19.1 0.0 0.0017 17.9 0.0 1.6 2 0 0 2 2 2 1 Hypothetical methyltransferase Glyco_transf_90 PF05686.7 KFX97645.1 - 0.045 12.4 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 E1_dh PF00676.15 KFX97646.1 - 2.2e-83 279.4 0.0 2.7e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFX97646.1 - 0.00014 21.4 0.1 0.0011 18.5 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFX97646.1 - 0.0027 16.5 0.0 0.0054 15.5 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain XFP_N PF09364.5 KFX97646.1 - 0.15 10.5 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain Smr PF01713.16 KFX97647.1 - 7e-11 42.1 0.3 1.8e-10 40.8 0.2 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KFX97647.1 - 2.6e-06 27.3 5.1 5.8e-06 26.2 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 KFX97647.1 - 0.00014 21.2 0.0 0.00033 20.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 KFX97647.1 - 0.042 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif HECT PF00632.20 KFX97648.1 - 6.9e-81 271.8 0.0 1.1e-80 271.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 KFX97648.1 - 0.04 13.7 3.2 19 5.2 0.1 5.3 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat Ribophorin_I PF04597.9 KFX97654.1 - 7.6e-151 502.4 1.1 8.7e-151 502.2 0.7 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.11 KFX97655.1 - 1.9e-87 292.5 0.0 2.5e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KFX97655.1 - 7.5e-75 250.7 0.0 1.2e-73 246.8 0.0 2.0 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 KFX97655.1 - 0.044 13.0 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Asp-Al_Ex PF06826.7 KFX97655.1 - 0.076 12.5 0.7 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Predicted Permease Membrane Region PhnJ PF06007.6 KFX97655.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Ank_2 PF12796.2 KFX97656.1 - 0.0024 18.1 0.1 0.034 14.4 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Rhodanese PF00581.15 KFX97660.1 - 2e-12 47.4 0.0 5e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF2823 PF11034.3 KFX97661.1 - 2.5e-30 104.3 6.4 2.8e-30 104.2 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Tombus_movement PF05318.7 KFX97661.1 - 8.5 7.0 7.4 47 4.7 5.2 2.0 1 1 0 1 1 1 0 Tombusvirus movement protein N-SET PF11764.3 KFX97681.1 - 8.9e-39 133.0 0.5 8.9e-39 133.0 0.4 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KFX97681.1 - 3.2e-22 79.5 0.1 3.2e-22 79.5 0.1 3.6 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 KFX97681.1 - 1.4e-17 62.7 0.0 2.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.1 KFX97681.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif INSIG PF07281.7 KFX97682.1 - 2e-47 161.0 1.9 2.5e-47 160.7 1.3 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) GST_C_2 PF13410.1 KFX97694.1 - 6.3e-09 35.6 0.7 1.2e-08 34.6 0.2 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX97694.1 - 0.0003 21.2 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX97694.1 - 0.00069 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Antitoxin-MazE PF04014.13 KFX97694.1 - 0.51 10.1 2.9 0.53 10.0 0.0 2.4 3 0 0 3 3 3 0 Antidote-toxin recognition MazE Ribosomal_L9_N PF01281.14 KFX97695.1 - 3.7e-10 38.8 0.0 8.4e-10 37.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 KFX97695.1 - 0.00016 21.6 1.0 0.72 9.9 0.0 3.5 4 0 0 4 4 4 2 Ribosomal protein L9, C-terminal domain Big_3 PF07523.7 KFX97695.1 - 0.093 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) F_bP_aldolase PF01116.15 KFX97696.1 - 6.1e-96 320.8 0.0 6.9e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.1 KFX97696.1 - 0.11 12.4 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like COP-gamma_platf PF08752.5 KFX97696.1 - 0.15 11.9 0.1 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Coatomer gamma subunit appendage platform subdomain Oxysterol_BP PF01237.13 KFX97697.1 - 1e-89 300.4 0.0 1.2e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PIG-F PF06699.6 KFX97697.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F zf-C2H2 PF00096.21 KFX97709.1 - 4e-05 23.6 7.0 0.005 17.1 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX97709.1 - 0.00026 21.0 9.3 0.0036 17.5 0.5 3.1 2 1 1 3 3 3 2 C2H2-type zinc finger DUF4106 PF13388.1 KFX97709.1 - 0.0053 15.7 1.4 0.0079 15.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) zf-H2C2_2 PF13465.1 KFX97709.1 - 0.024 14.9 3.0 0.024 14.9 2.1 3.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.2 KFX97709.1 - 0.33 11.2 3.8 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AMP-binding PF00501.23 KFX97717.1 - 6.8e-93 311.3 0.6 8.3e-93 311.0 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX97717.1 - 1.8e-21 76.8 0.3 1.1e-19 71.1 0.1 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 KFX97731.1 - 1.7e-66 224.6 0.0 1.9e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_18 PF12847.2 KFX97732.1 - 2.1e-10 41.1 0.3 4.6e-10 40.0 0.2 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97732.1 - 9.6e-10 38.2 0.0 1.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97732.1 - 3.7e-08 33.2 0.0 6.8e-08 32.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX97732.1 - 3.8e-08 32.7 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KFX97732.1 - 2.1e-07 31.2 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX97732.1 - 1.1e-05 24.8 0.0 3.2e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KFX97732.1 - 5.6e-05 23.5 0.0 9.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97732.1 - 0.00027 21.3 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97732.1 - 0.00045 20.2 0.2 0.00091 19.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX97732.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KFX97732.1 - 0.0089 15.4 0.0 0.019 14.3 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KFX97732.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFX97732.1 - 0.037 13.1 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.8 KFX97732.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_2 PF00891.13 KFX97732.1 - 0.08 12.1 0.0 8.3 5.5 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase DOT1 PF08123.8 KFX97732.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 GMC_oxred_N PF00732.14 KFX97735.1 - 3.9e-50 170.6 0.1 5e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX97735.1 - 4.5e-39 134.0 0.1 7.7e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX97735.1 - 1.6e-07 30.6 0.2 0.0033 16.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX97735.1 - 1.6e-05 24.0 0.0 0.00033 19.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFX97735.1 - 9.6e-05 22.5 0.1 0.27 11.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX97735.1 - 0.00012 21.9 0.2 0.11 12.2 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX97735.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFX97735.1 - 0.0045 15.9 0.3 0.59 8.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFX97735.1 - 0.012 14.5 0.2 0.021 13.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KFX97735.1 - 0.031 14.1 0.2 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX97735.1 - 0.047 12.3 0.1 0.071 11.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Amidohydro_2 PF04909.9 KFX97737.1 - 1.7e-46 159.0 0.2 2.1e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase UBN2 PF14223.1 KFX97737.1 - 0.11 12.2 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KFX97737.1 - 0.18 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type COesterase PF00135.23 KFX97738.1 - 1.7e-85 287.8 0.1 2.3e-85 287.3 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX97738.1 - 0.012 15.1 0.0 0.043 13.3 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold TPR_10 PF13374.1 KFX97739.1 - 8.2e-94 305.2 18.4 1.1e-10 41.0 0.0 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.1 KFX97739.1 - 9.9e-90 294.5 9.1 9.1e-20 70.3 0.1 6.4 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 KFX97739.1 - 3.4e-38 126.4 14.5 0.00013 21.4 0.0 10.3 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 KFX97739.1 - 9e-34 113.7 26.6 7.2e-05 22.2 0.3 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KFX97739.1 - 8.9e-32 108.5 3.6 2.1e-08 33.6 0.4 6.1 4 1 3 7 7 6 6 TPR repeat TPR_2 PF07719.12 KFX97739.1 - 3.2e-26 89.1 23.1 0.0088 15.8 0.4 9.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFX97739.1 - 1.1e-25 89.6 10.4 6.6e-07 29.8 0.1 6.7 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97739.1 - 1.7e-19 68.5 16.3 0.36 11.5 0.0 10.5 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFX97739.1 - 4.7e-16 57.5 1.3 3.5 8.0 0.0 10.3 9 1 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX97739.1 - 2.3e-13 50.0 0.0 0.0029 17.6 0.1 6.4 2 1 6 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFX97739.1 - 4.8e-13 48.1 0.0 2.6 8.7 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX97739.1 - 1.1e-12 46.7 18.0 1.9 8.4 0.1 9.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX97739.1 - 3.8e-11 43.1 15.3 0.21 11.9 1.3 7.3 6 2 3 9 9 8 5 Tetratricopeptide repeat Atu4866 PF11512.3 KFX97739.1 - 2.9e-09 36.5 17.8 0.24 11.1 0.1 7.7 3 3 4 7 7 7 4 Agrobacterium tumefaciens protein Atu4866 NB-ARC PF00931.17 KFX97739.1 - 4.2e-08 32.3 0.0 0.00038 19.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Rab5-bind PF09311.6 KFX97739.1 - 8e-07 29.1 6.8 0.0025 17.7 0.5 4.6 2 1 1 4 4 4 2 Rabaptin-like protein AAA_22 PF13401.1 KFX97739.1 - 0.00047 20.3 0.0 0.0021 18.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF1925 PF09094.6 KFX97739.1 - 0.00075 19.4 5.4 30 4.6 0.0 6.1 5 2 0 6 6 6 0 Domain of unknown function (DUF1925) Tcf25 PF04910.9 KFX97739.1 - 0.0039 16.1 0.3 30 3.4 0.0 4.8 4 1 1 5 5 5 0 Transcriptional repressor TCF25 FTCD PF02971.9 KFX97739.1 - 0.056 13.0 0.8 62 3.1 0.0 4.9 3 2 3 6 6 6 0 Formiminotransferase domain BTAD PF03704.12 KFX97739.1 - 0.42 10.8 10.4 2.1 8.6 0.2 4.4 3 1 1 4 4 4 0 Bacterial transcriptional activator domain OSR1_C PF12202.3 KFX97739.1 - 2.3 7.9 4.0 46 3.7 0.1 4.3 4 0 0 4 4 4 0 Oxidative-stress-responsive kinase 1 C terminal Sugar_tr PF00083.19 KFX97740.1 - 3.9e-82 276.2 17.7 4.6e-82 276.0 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97740.1 - 1e-15 57.3 45.1 1.4e-14 53.5 15.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX97740.1 - 1.4e-06 27.0 22.8 0.0029 16.0 0.2 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein DUF3671 PF12420.3 KFX97740.1 - 1.4 8.9 6.9 5.3 7.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function Alpha-amylase PF00128.19 KFX97741.1 - 5.7e-96 321.6 2.8 7.8e-96 321.1 1.9 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFX97741.1 - 0.021 13.7 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF3459 PF11941.3 KFX97741.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Amidase PF01425.16 KFX97742.1 - 1.2e-83 281.4 0.0 4.4e-83 279.5 0.0 1.8 2 0 0 2 2 2 1 Amidase MFS_1 PF07690.11 KFX97742.1 - 6e-28 97.5 47.8 9.9e-28 96.8 33.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX97742.1 - 0.00014 20.3 18.2 0.00014 20.3 12.6 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 KFX97743.1 - 2.1e-15 56.3 29.9 3.6e-09 35.7 8.4 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFX97744.1 - 9.6e-06 24.4 0.5 0.00026 19.7 0.3 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 KFX97745.1 - 2.3e-20 73.2 0.4 5e-19 68.8 0.1 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) PC_rep PF01851.17 KFX97746.1 - 0.0001 22.3 0.0 6.4 7.2 0.1 5.5 6 0 0 6 6 6 2 Proteasome/cyclosome repeat Bac_luciferase PF00296.15 KFX97747.1 - 3.4e-58 197.2 0.8 5.1e-58 196.6 0.6 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase UNC-93 PF05978.11 KFX97748.1 - 1.2e-07 31.3 3.4 1.2e-07 31.3 2.4 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 KFX97748.1 - 7.7e-06 24.8 34.5 7.7e-06 24.8 23.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KFX97749.1 - 6e-26 91.7 0.0 4.1e-25 89.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX97749.1 - 3e-16 58.7 0.0 3.5e-15 55.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX97749.1 - 2.9e-09 37.0 0.0 2.8e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX97749.1 - 6.4e-09 35.7 0.0 4.1e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFX97749.1 - 1.3e-08 34.1 0.6 6.3e-08 31.9 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFX97749.1 - 0.00023 20.3 0.1 0.00096 18.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFX97749.1 - 0.00034 19.6 0.9 0.05 12.5 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX97749.1 - 0.00081 19.1 0.8 0.39 10.4 0.1 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 KFX97749.1 - 0.052 13.1 0.1 0.47 10.0 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KFX97749.1 - 0.14 11.1 0.5 0.23 10.4 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain F-box PF00646.28 KFX97750.1 - 0.00054 19.5 0.6 0.0014 18.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX97750.1 - 0.049 13.3 0.1 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like VID27 PF08553.5 KFX97751.1 - 0 1131.9 0.1 0 1131.8 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Glyco_transf_20 PF00982.16 KFX97752.1 - 1.2e-195 650.5 0.0 1.4e-195 650.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Drc1-Sld2 PF11719.3 KFX97753.1 - 1.7e-40 139.4 5.5 2.1e-40 139.1 3.8 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein GOLGA2L5 PF15070.1 KFX97759.1 - 0.027 12.9 1.3 0.046 12.2 0.9 1.3 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.10 KFX97759.1 - 0.19 11.2 1.4 0.37 10.3 0.9 1.4 1 0 0 1 1 1 0 Septum formation initiator TMF_DNA_bd PF12329.3 KFX97759.1 - 0.25 11.1 3.9 0.12 12.2 1.1 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 KFX97759.1 - 0.38 10.7 4.9 0.13 12.2 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-CHY PF05495.7 KFX97761.1 - 6e-17 61.5 15.2 6e-17 61.5 10.5 3.7 4 0 0 4 4 4 2 CHY zinc finger Mu-like_Com PF10122.4 KFX97761.1 - 0.012 14.6 3.4 0.078 12.0 0.5 3.1 2 0 0 2 2 2 0 Mu-like prophage protein Com Cpn60_TCP1 PF00118.19 KFX97762.1 - 1.5e-147 492.1 2.7 1.7e-147 491.9 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RepB PF07506.6 KFX97763.1 - 0.18 11.6 1.6 1.1 9.0 0.1 2.4 1 1 1 2 2 2 0 RepB plasmid partitioning protein DUF1777 PF08648.7 KFX97764.1 - 0.29 10.8 8.6 0.39 10.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) adh_short_C2 PF13561.1 KFX97769.1 - 4.6e-28 98.5 0.0 5.5e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX97769.1 - 4.8e-10 39.5 0.7 1e-09 38.5 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX97769.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 KR domain Methyltransf_23 PF13489.1 KFX97770.1 - 8.8e-13 48.2 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97770.1 - 1.9e-12 47.5 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97770.1 - 9.6e-10 38.7 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97770.1 - 2.4e-08 33.6 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97770.1 - 2.8e-08 34.3 0.0 5.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97770.1 - 2.3e-06 28.0 0.0 4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97770.1 - 8.7e-06 25.7 0.1 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX97770.1 - 3.4e-05 23.0 0.0 4.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KFX97770.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain adh_short PF00106.20 KFX97771.1 - 1.5e-15 57.5 2.9 4.8e-15 55.8 0.3 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Acetyltransf_1 PF00583.19 KFX97771.1 - 4.2e-11 42.7 0.0 1.2e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family KR PF08659.5 KFX97771.1 - 6.7e-08 32.3 0.2 3.2e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 KR domain Acetyltransf_7 PF13508.1 KFX97771.1 - 7.7e-08 32.3 0.0 2.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX97771.1 - 6.7e-06 25.7 0.0 3.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KFX97771.1 - 1.1e-05 25.5 0.0 4.2e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.1 KFX97771.1 - 9.1e-05 22.3 0.1 0.00013 21.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_9 PF13527.1 KFX97771.1 - 0.00017 21.4 0.0 0.0091 15.8 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Epimerase PF01370.16 KFX97771.1 - 0.00045 19.7 0.1 0.00085 18.8 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97771.1 - 0.0065 16.5 1.4 0.017 15.1 0.6 2.1 1 1 1 2 2 2 1 NADH(P)-binding Acetyltransf_CG PF14542.1 KFX97771.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase 3Beta_HSD PF01073.14 KFX97771.1 - 0.036 12.7 0.1 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 KFX97771.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyoxalase_2 PF12681.2 KFX97772.1 - 7.3e-07 29.7 0.0 9.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFX97772.1 - 6.3e-06 26.1 0.0 1.4e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank PF00023.25 KFX97774.1 - 3.2e-14 51.9 0.1 3e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 KFX97774.1 - 4.3e-12 45.8 2.1 5.7e-12 45.4 0.2 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 KFX97774.1 - 8.4e-11 42.0 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFX97774.1 - 9.6e-09 34.6 0.1 0.00074 19.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFX97774.1 - 2e-08 34.5 0.0 1.2e-07 32.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX97774.1 - 2.1e-08 34.1 0.1 0.00024 21.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Cauli_VI PF01693.11 KFX97775.1 - 1.5e-33 114.4 3.2 2.7e-17 62.4 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KFX97775.1 - 2.8e-26 92.4 0.0 4.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNase H dCMP_cyt_deam_1 PF00383.17 KFX97776.1 - 2.8e-08 33.3 0.1 8e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Arm PF00514.18 KFX97777.1 - 1.6e-13 49.9 16.8 9.2e-06 25.2 0.1 9.6 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFX97777.1 - 3.7e-06 26.5 14.0 1.6 9.0 0.1 7.5 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 KFX97777.1 - 0.00012 22.2 10.3 3.2 8.0 0.0 6.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KFX97777.1 - 0.0023 18.3 13.3 0.75 10.3 0.1 6.5 7 0 0 7 7 7 2 HEAT-like repeat V-ATPase_H_C PF11698.3 KFX97777.1 - 0.083 12.8 0.3 4.7 7.1 0.1 3.0 2 1 1 3 3 3 0 V-ATPase subunit H 6PF2K PF01591.13 KFX97778.1 - 1.8e-62 210.3 0.0 2.2e-43 147.9 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFX97778.1 - 2.1e-24 86.3 0.0 7.1e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFX97778.1 - 0.00012 21.9 0.0 0.0015 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFX97778.1 - 0.023 13.9 0.0 0.076 12.2 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFX97778.1 - 0.04 14.7 0.0 0.2 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFX97778.1 - 0.048 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CARD PF00619.16 KFX97778.1 - 0.056 13.2 0.3 0.21 11.4 0.2 2.0 1 1 0 1 1 1 0 Caspase recruitment domain CHZ PF09649.5 KFX97779.1 - 1.2e-19 69.2 2.2 1.2e-19 69.2 1.5 2.3 3 0 0 3 3 3 1 Histone chaperone domain CHZ HNF-1_N PF04814.8 KFX97779.1 - 7.4 6.6 7.0 1.7 8.7 2.5 1.6 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus BUD22 PF09073.5 KFX97779.1 - 8.7 5.2 17.8 10 5.0 12.4 1.0 1 0 0 1 1 1 0 BUD22 SNARE PF05739.14 KFX97780.1 - 2e-09 36.9 1.6 2.8e-09 36.5 1.1 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KFX97780.1 - 0.014 14.8 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Apc15p PF05841.6 KFX97781.1 - 7.4e-20 71.9 0.6 7.4e-20 71.9 0.4 2.0 2 0 0 2 2 2 1 Apc15p protein DUF3306 PF11748.3 KFX97781.1 - 5.7 7.6 8.3 22 5.7 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) Glu_synthase PF01645.12 KFX97782.1 - 6e-160 532.1 0.0 1.1e-159 531.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KFX97782.1 - 2.6e-139 463.9 0.0 3.4e-139 463.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KFX97782.1 - 5.7e-117 390.0 0.0 9.5e-117 389.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KFX97782.1 - 7.2e-68 227.5 5.2 1.5e-67 226.5 3.6 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KFX97782.1 - 5.7e-23 80.6 0.1 1.4e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KFX97782.1 - 1.2e-14 54.7 0.0 5.6e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX97782.1 - 1.6e-10 41.4 0.1 0.0005 20.1 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX97782.1 - 2.6e-08 33.7 0.0 9.4e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX97782.1 - 3.5e-07 30.5 0.0 0.00079 19.7 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX97782.1 - 1.7e-05 23.5 0.0 4.9e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 KFX97782.1 - 4.7e-05 22.6 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KFX97782.1 - 9.7e-05 21.4 0.1 0.00032 19.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX97782.1 - 0.001 18.0 0.1 0.0038 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KFX97782.1 - 0.0013 17.8 0.1 0.0061 15.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 KFX97782.1 - 0.0014 18.8 1.8 1.5 9.1 0.0 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 KFX97782.1 - 0.0067 16.2 0.4 4.7 7.0 0.0 2.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.14 KFX97782.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.14 KFX97782.1 - 0.016 13.4 0.1 5 5.2 0.0 2.7 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 KFX97782.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KFX97782.1 - 0.05 13.1 0.2 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KFX97782.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMN_dh PF01070.13 KFX97782.1 - 0.12 11.1 0.8 0.41 9.4 0.5 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DJ-1_PfpI PF01965.19 KFX97782.1 - 0.14 11.6 0.4 3.3 7.1 0.1 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family VTC PF09359.5 KFX97783.1 - 4.6e-97 324.4 0.5 7.5e-97 323.7 0.3 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KFX97783.1 - 6.9e-17 62.1 15.0 7e-13 48.9 7.2 3.6 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KFX97783.1 - 2e-10 40.7 3.3 5.2e-10 39.3 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Seryl_tRNA_N PF02403.17 KFX97783.1 - 0.17 11.8 4.4 0.27 11.2 0.9 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nic96 PF04097.9 KFX97785.1 - 2.9e-183 610.3 0.0 3.7e-183 609.9 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 UPF0029 PF01205.14 KFX97785.1 - 1.2e-26 92.5 0.0 2.6e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Nucleoporin_FG PF13634.1 KFX97785.1 - 0.00071 19.7 36.1 0.00071 19.7 25.0 2.9 3 0 0 3 3 3 1 Nucleoporin FG repeat region Seipin PF06775.9 KFX97786.1 - 4.4e-59 199.3 0.0 5.5e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) QCR10 PF09796.4 KFX97786.1 - 0.064 12.9 0.2 0.064 12.9 0.1 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) CorA PF01544.13 KFX97787.1 - 2.7e-08 33.1 0.6 4.3e-08 32.5 0.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spermine_synth PF01564.12 KFX97789.1 - 2.3e-10 39.8 0.0 3.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KFX97789.1 - 1e-07 32.0 0.2 2.6e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97789.1 - 2.3e-05 24.9 0.0 6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97789.1 - 0.0031 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97789.1 - 0.0046 17.3 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97789.1 - 0.016 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 KFX97789.1 - 0.056 13.1 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 KFX97789.1 - 0.08 13.4 0.0 0.34 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 KFX97790.1 - 2e-24 85.9 0.3 3.3e-24 85.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LSM PF01423.17 KFX97806.1 - 5.6e-13 48.2 0.0 8.6e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain PAT1 PF09770.4 KFX97806.1 - 5.9 4.9 12.8 7 4.7 8.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorismate_bind PF00425.13 KFX97807.1 - 6.9e-89 297.5 0.0 8.1e-87 290.7 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 KFX97807.1 - 5.3e-29 101.0 0.1 5.1e-25 88.1 0.0 3.4 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Sugar_tr PF00083.19 KFX97816.1 - 4.4e-81 272.7 21.8 5.4e-81 272.4 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97816.1 - 1.8e-30 105.8 24.7 2.3e-27 95.6 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX97816.1 - 0.00038 18.7 4.1 0.0013 17.0 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2781 PF10914.3 KFX97816.1 - 0.051 13.3 0.1 0.051 13.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2781) HTH_37 PF13744.1 KFX97816.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Fungal_trans_2 PF11951.3 KFX97817.1 - 7.1e-23 80.8 0.0 1.3e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KFX97817.1 - 5.3e-17 61.5 0.3 1.2e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX97817.1 - 2.4e-06 27.3 1.4 5.5e-06 26.1 1.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.6 KFX97818.1 - 3.9e-10 39.0 0.0 7.7e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KFX97818.1 - 3.4e-06 26.5 0.0 4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.7 KFX97818.1 - 2.3e-05 23.8 0.0 2.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.7 KFX97818.1 - 9.7e-05 21.6 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_4 PF08007.7 KFX97818.1 - 0.0064 15.7 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein ARD PF03079.9 KFX97818.1 - 0.0081 16.1 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family FdtA PF05523.6 KFX97818.1 - 0.039 13.4 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal HgmA PF04209.8 KFX97818.1 - 0.075 11.4 0.0 0.084 11.2 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Cupin_6 PF12852.2 KFX97818.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Cupin AA_permease PF00324.16 KFX97819.1 - 4.3e-138 460.6 36.3 5e-138 460.4 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX97819.1 - 6.7e-38 130.3 38.5 9.1e-38 129.8 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KFX97820.1 - 2.8e-38 131.5 24.2 2.8e-38 131.5 16.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 KFX97820.1 - 1.9 8.6 12.4 3 7.9 2.3 3.9 3 0 0 3 3 3 0 2TM domain Fungal_trans PF04082.13 KFX97821.1 - 1.3e-25 89.7 0.2 1.3e-25 89.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97821.1 - 3.8e-08 33.1 11.9 7.6e-08 32.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex24p PF06398.6 KFX97825.1 - 1.6e-35 122.5 14.9 2e-35 122.2 10.3 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PARP PF00644.15 KFX97827.1 - 1.7e-12 47.1 0.0 1.7e-09 37.4 0.0 2.5 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.11 KFX97827.1 - 0.1 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family cobW PF02492.14 KFX97829.1 - 1.5e-37 128.7 0.0 2.2e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFX97829.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KFX97829.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFX97829.1 - 0.019 14.4 0.3 0.28 10.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KFX97829.1 - 0.03 14.0 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain BESS PF02944.15 KFX97829.1 - 0.046 13.2 0.3 0.087 12.3 0.2 1.4 1 0 0 1 1 1 0 BESS motif Viral_helicase1 PF01443.13 KFX97829.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KFX97829.1 - 0.099 12.7 0.0 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX97829.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ETC_C1_NDUFA5 PF04716.9 KFX97829.1 - 0.2 11.1 0.4 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region Stm1_N PF09598.5 KFX97831.1 - 0.42 11.3 8.6 0.6 10.8 5.9 1.2 1 0 0 1 1 1 0 Stm1 YL1 PF05764.8 KFX97831.1 - 0.85 9.1 5.7 1.1 8.8 4.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF1752 PF08550.5 KFX97843.1 - 7.1e-07 28.6 3.7 1.3e-06 27.8 2.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF849 PF05853.7 KFX97843.1 - 0.014 14.2 0.2 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) SPATA24 PF15175.1 KFX97856.1 - 0.45 10.1 4.5 0.95 9.1 3.2 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 FMN_dh PF01070.13 KFX97870.1 - 2.1e-103 345.9 0.0 2.6e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFX97870.1 - 2.5e-22 78.4 0.0 5.9e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KFX97870.1 - 1.8e-07 30.4 0.2 3.1e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFX97870.1 - 1.4e-05 24.1 0.5 0.00024 20.1 0.2 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KFX97870.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.10 KFX97870.1 - 0.021 13.9 0.2 0.044 12.9 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase BPL_C PF02237.12 KFX97870.1 - 0.022 14.4 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DHO_dh PF01180.16 KFX97870.1 - 0.032 13.1 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KFX97870.1 - 0.038 13.0 0.0 5.8 5.9 0.0 2.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.14 KFX97870.1 - 0.088 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ATP11 PF06644.6 KFX97870.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein adh_short_C2 PF13561.1 KFX97871.1 - 8.9e-20 71.4 0.1 1.3e-19 70.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX97871.1 - 1.1e-18 67.7 2.8 1.5e-18 67.2 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX97871.1 - 3e-06 27.0 2.9 1.2e-05 25.0 2.0 1.7 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFX97871.1 - 0.062 13.3 0.1 0.22 11.6 0.2 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1772 PF08592.6 KFX97872.1 - 0.00017 21.3 1.6 0.0075 16.0 1.9 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) DUF1932 PF09130.6 KFX97873.1 - 6.7e-18 64.1 0.0 1.6e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 KFX97873.1 - 1.4e-06 28.6 0.0 3.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFX97873.1 - 6.1e-06 26.1 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFX97873.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KFX97873.1 - 0.079 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.13 KFX97873.1 - 0.12 11.9 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RanBP PF00641.13 KFX97874.1 - 0.24 10.5 3.2 0.5 9.5 2.2 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-B_box PF00643.19 KFX97874.1 - 0.39 10.6 4.2 0.92 9.4 2.9 1.5 1 0 0 1 1 1 0 B-box zinc finger RRM_1 PF00076.17 KFX97875.1 - 8.2e-17 60.6 0.0 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97875.1 - 6.6e-12 45.2 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFX97875.1 - 1.6e-07 31.6 8.6 1.6e-07 31.6 6.0 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KFX97875.1 - 8.8e-07 28.6 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FCP1_C PF09309.5 KFX97875.1 - 7.3 5.8 14.2 4.5 6.4 1.8 2.3 2 0 0 2 2 2 0 FCP1, C-terminal Rad10 PF03834.9 KFX97876.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) p450 PF00067.17 KFX97877.1 - 2.1e-73 247.4 0.0 8.7e-73 245.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 SBF PF01758.11 KFX97882.1 - 3.5e-45 153.7 15.0 3.5e-45 153.7 10.4 2.0 2 1 0 2 2 2 1 Sodium Bile acid symporter family LMWPc PF01451.16 KFX97883.1 - 4.2e-29 101.6 0.0 4.9e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1470 PF07336.6 KFX97883.1 - 0.038 14.3 0.7 0.067 13.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) DUF1488 PF07369.6 KFX97883.1 - 0.099 12.4 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Pyr_redox_2 PF07992.9 KFX97884.1 - 2.7e-27 95.9 0.3 3.4e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX97884.1 - 1.5e-17 63.7 1.6 2.6e-15 56.5 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX97884.1 - 2.1e-09 37.7 0.0 7.6e-06 26.1 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFX97884.1 - 4.3e-06 26.9 0.1 0.0011 19.2 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KFX97884.1 - 1.6e-05 24.8 0.2 0.018 15.0 0.0 3.2 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX97884.1 - 4e-05 22.8 0.1 0.00024 20.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFX97884.1 - 0.00013 20.9 0.2 1.5 7.6 0.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX97884.1 - 0.013 14.3 5.1 0.13 11.1 0.2 3.0 2 1 0 3 3 3 0 FAD binding domain GIDA PF01134.17 KFX97884.1 - 0.022 13.6 4.9 1.4 7.6 0.2 3.4 3 1 1 4 4 4 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFX97884.1 - 0.024 13.2 0.1 0.24 9.9 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.14 KFX97884.1 - 0.024 13.6 0.2 2 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 KFX97884.1 - 0.028 13.3 0.0 0.18 10.6 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KFX97884.1 - 0.07 13.2 0.2 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KFX97884.1 - 0.094 11.1 0.4 1.1 7.6 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Bul1_C PF04426.7 KFX97885.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Arrestin_N PF00339.24 KFX97886.1 - 4.9e-07 29.6 0.0 3.2e-06 27.0 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HLH PF00010.21 KFX97886.1 - 8.9e-07 28.5 0.9 2.4e-06 27.1 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_72 PF03198.9 KFX97887.1 - 4e-127 423.5 0.1 5.1e-127 423.1 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFX97887.1 - 2.9e-05 23.4 0.1 0.00023 20.4 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chromate_transp PF02417.10 KFX97889.1 - 9.2e-52 175.0 33.5 3.6e-27 95.0 8.9 2.4 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.9 KFX97889.1 - 0.049 12.6 0.1 0.3 10.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Meth_synt_2 PF01717.13 KFX97892.1 - 4.4e-146 485.9 0.0 1.3e-139 464.6 0.0 3.3 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFX97892.1 - 6e-124 413.3 0.5 1.1e-111 373.1 0.1 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KFX97892.1 - 0.0035 16.3 0.1 1 8.1 0.0 3.0 4 0 0 4 4 4 2 Uroporphyrinogen decarboxylase (URO-D) TSSC4 PF15264.1 KFX97892.1 - 0.057 13.8 0.3 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 Alpha_L_fucos PF01120.12 KFX97892.1 - 0.062 12.1 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-fucosidase SHOCT PF09851.4 KFX97892.1 - 0.078 12.4 0.2 0.078 12.4 0.2 2.9 3 0 0 3 3 3 0 Short C-terminal domain Glyco_hyd_65N_2 PF14498.1 KFX97894.1 - 0.0071 16.0 0.1 0.023 14.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 KFX97895.1 - 3.2e-89 299.5 27.1 3.8e-89 299.3 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97895.1 - 2e-25 89.2 64.6 1.6e-21 76.3 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX97895.1 - 0.00049 18.4 3.9 0.00049 18.4 2.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFX97895.1 - 0.0012 16.9 6.8 0.0053 14.8 1.1 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Amidohydro_1 PF01979.15 KFX97896.1 - 4.9e-33 115.1 0.0 7.4e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family A_deaminase PF00962.17 KFX97896.1 - 0.0015 17.5 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 KFX97896.1 - 0.0017 17.6 2.8 0.026 13.7 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFX97896.1 - 0.0049 16.9 0.8 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KFX97896.1 - 0.0063 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_61 PF03443.9 KFX97897.1 - 9.1e-80 267.5 0.3 1.4e-79 266.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Dyp_perox PF04261.7 KFX97898.1 - 4.7e-92 308.0 0.0 5.3e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family cobW PF02492.14 KFX97900.1 - 1.5e-34 118.9 0.0 1.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KFX97900.1 - 6e-06 25.2 0.1 0.012 14.4 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 KFX97900.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KFX97900.1 - 0.0068 16.3 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KFX97900.1 - 0.016 16.0 0.1 0.027 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX97900.1 - 0.049 13.0 0.5 0.12 11.7 0.4 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KFX97900.1 - 0.073 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 KFX97900.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 KFX97900.1 - 0.081 12.3 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 KFX97900.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TMEM51 PF15345.1 KFX97900.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Glyco_hyd_65N_2 PF14498.1 KFX97906.1 - 1.9e-48 165.1 0.0 3.2e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HET PF06985.6 KFX97907.1 - 4.9e-21 75.3 0.0 9.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_transf_34 PF05637.7 KFX97908.1 - 2e-72 243.5 0.0 3.2e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pyridoxal_deC PF00282.14 KFX97908.1 - 7.2e-16 57.5 0.0 1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFX97908.1 - 0.014 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF273 PF03314.9 KFX97908.1 - 0.015 14.6 0.0 0.7 9.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF273 Resolvase PF00239.16 KFX97908.1 - 0.2 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain PMI_typeI PF01238.16 KFX97909.1 - 2.5e-65 220.8 0.0 2e-64 217.9 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KFX97909.1 - 0.0013 18.2 0.2 0.96 8.9 0.2 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KFX97909.1 - 0.086 12.5 0.1 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain AMP-binding PF00501.23 KFX97912.1 - 3.6e-86 289.1 0.0 4.5e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX97912.1 - 8e-15 55.5 0.0 2.2e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KFX97912.1 - 0.0025 16.4 0.0 0.0098 14.4 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Glyco_hydro_61 PF03443.9 KFX97913.1 - 3.6e-54 183.8 0.0 5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPAM_1 PF08139.7 KFX97913.1 - 0.73 10.1 3.4 4.4 7.6 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site NAD_binding_2 PF03446.10 KFX97914.1 - 2.6e-26 92.4 0.0 4.5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFX97914.1 - 1.8e-09 37.7 0.1 3.5e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFX97914.1 - 3.3e-08 33.8 0.1 8.9e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KFX97914.1 - 2.3e-06 27.7 0.0 4.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 KFX97914.1 - 0.054 12.2 0.3 0.08 11.6 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.19 KFX97915.1 - 5.6e-71 239.4 12.6 1.6e-69 234.6 4.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFX97915.1 - 2.5e-18 65.9 20.4 3.4e-18 65.4 14.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX97915.1 - 0.00034 19.1 12.2 0.03 12.7 0.3 3.3 3 0 0 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 KFX97915.1 - 0.0078 14.4 0.8 0.012 13.8 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 KFX97916.1 - 7.4e-09 35.3 8.4 1.3e-08 34.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX97916.1 - 0.0017 17.3 0.2 0.0031 16.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 KFX97917.1 - 6.4e-85 284.7 0.0 9.8e-85 284.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX97917.1 - 5.2e-70 235.5 0.0 2.1e-69 233.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX97917.1 - 1.4e-20 72.9 1.3 3.1e-20 71.8 0.6 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KFX97917.1 - 5e-14 52.1 0.2 9.9e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.1 KFX97917.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CARDB PF07705.6 KFX97917.1 - 0.071 13.1 0.4 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 CARDB Acetyltransf_7 PF13508.1 KFX97926.1 - 2.2e-06 27.7 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX97926.1 - 1.4e-05 24.9 0.1 3.7e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX97926.1 - 0.019 14.9 0.3 0.05 13.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Ank_2 PF12796.2 KFX97927.1 - 2.1e-44 149.7 0.2 9.1e-18 64.3 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX97927.1 - 1.6e-36 123.4 3.0 7.4e-09 35.5 0.0 6.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KFX97927.1 - 8.1e-36 120.0 4.9 5.7e-06 25.8 0.0 8.1 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFX97927.1 - 2.9e-32 110.4 1.1 9.8e-10 38.6 0.1 6.1 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX97927.1 - 1.3e-23 80.6 0.3 0.00098 19.1 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat DBD_Tnp_Hermes PF10683.4 KFX97927.1 - 0.031 13.7 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF2387 PF09526.5 KFX97927.1 - 0.041 13.8 0.6 0.099 12.5 0.4 1.6 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) FAD_binding_3 PF01494.14 KFX97928.1 - 2.8e-16 59.5 0.1 1.7e-15 56.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KFX97928.1 - 0.024 13.2 0.1 0.065 11.8 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase CFEM PF05730.6 KFX97931.1 - 2.3e-10 40.1 10.5 3.5e-10 39.5 7.2 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_61 PF03443.9 KFX97932.1 - 3.9e-79 265.4 0.0 4.5e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFX97932.1 - 0.0071 16.3 0.1 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Big_3_4 PF13754.1 KFX97932.1 - 0.017 15.4 0.1 0.074 13.3 0.1 2.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) GPI-anchored PF10342.4 KFX97932.1 - 0.1 13.0 0.2 7.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.27 KFX97945.1 - 2.2e-26 90.7 14.1 3.5e-09 36.1 0.0 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat DEAD PF00270.24 KFX97946.1 - 5.3e-41 139.9 0.0 9.9e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA_pol_Rpb5_C PF01191.14 KFX97946.1 - 1.4e-32 111.1 0.3 3.7e-32 109.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KFX97946.1 - 5.7e-28 97.1 0.0 1.2e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Helicase_C PF00271.26 KFX97946.1 - 5.8e-22 77.3 0.4 2.2e-21 75.4 0.3 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFX97946.1 - 0.005 15.6 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFX97946.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KFX97946.1 - 0.037 13.3 0.2 0.32 10.2 0.0 2.2 3 0 0 3 3 3 0 SecA DEAD-like domain Mrr_cat PF04471.7 KFX97946.1 - 0.046 13.5 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease CENP-F_leu_zip PF10473.4 KFX97947.1 - 0.00089 19.1 13.4 0.00089 19.1 9.3 3.9 3 2 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Propeptide_C1 PF08127.8 KFX97947.1 - 0.017 14.6 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C1 propeptide GTP1_OBG PF01018.17 KFX97949.1 - 5.6e-36 123.5 5.3 4.4e-27 94.6 2.8 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KFX97949.1 - 2.1e-21 76.0 0.0 3.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX97949.1 - 2.2e-07 30.2 0.1 5e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KFX97949.1 - 0.063 12.0 0.0 0.38 9.4 0.0 2.0 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KFX97949.1 - 0.099 12.0 0.0 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFX97949.1 - 0.15 12.3 1.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Fungal_trans PF04082.13 KFX97951.1 - 3.8e-11 42.3 0.3 1e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97951.1 - 4.8e-09 35.9 10.3 8.6e-09 35.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 KFX97952.1 - 8.1e-84 281.9 3.2 1.1e-83 281.5 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.19 KFX97953.1 - 6.3e-83 278.8 25.6 7.1e-83 278.6 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97953.1 - 3.2e-15 55.7 30.1 3.2e-15 55.7 20.9 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX97953.1 - 0.00055 18.4 27.1 0.0018 16.7 4.8 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein NmrA PF05368.8 KFX97954.1 - 2.8e-36 124.9 0.0 3.7e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX97954.1 - 3.3e-14 53.2 0.0 4.2e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX97954.1 - 0.00047 18.9 0.0 0.00094 17.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFX97954.1 - 0.0024 17.5 0.0 0.0051 16.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFX97954.1 - 0.0033 16.8 0.0 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX97954.1 - 0.0036 16.2 0.0 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KFX97954.1 - 0.0079 16.1 0.0 0.017 15.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase DXP_reductoisom PF02670.11 KFX97954.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 KFX97954.1 - 0.11 12.3 0.1 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CDH PF02611.10 KFX97955.1 - 0.0052 16.0 0.1 0.0081 15.4 0.0 1.2 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase NACHT PF05729.7 KFX97956.1 - 1.1e-09 38.2 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 KFX97956.1 - 0.00011 22.1 0.7 0.00061 19.7 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX97956.1 - 0.00025 20.3 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFX97956.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX97956.1 - 0.0044 16.7 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.16 KFX97957.1 - 1e-18 67.6 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97957.1 - 6e-10 39.4 0.0 1.3e-09 38.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX97957.1 - 9.1e-05 21.4 0.0 0.00041 19.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFX97957.1 - 0.00025 20.9 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KFX97957.1 - 0.013 14.1 0.0 0.026 13.2 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KFX97957.1 - 0.026 13.7 0.0 6.3 5.9 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Ank_2 PF12796.2 KFX97958.1 - 2.7e-54 181.4 18.1 2.1e-17 63.2 0.5 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX97958.1 - 8.9e-37 123.0 25.4 5.1e-06 26.0 0.2 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KFX97958.1 - 1.4e-23 82.3 15.8 7.3e-05 22.8 0.1 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX97958.1 - 3.5e-23 81.5 5.9 2.2e-06 28.0 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX97958.1 - 3.3e-21 73.2 11.4 0.004 17.2 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat FLgD_tudor PF13861.1 KFX97958.1 - 0.034 14.1 0.0 0.79 9.7 0.0 3.0 2 1 0 2 2 2 0 FlgD Tudor-like domain CholecysA-Rec_N PF09193.5 KFX97958.1 - 0.04 13.8 0.7 11 5.9 0.0 3.7 5 0 0 5 5 5 0 Cholecystokinin A receptor, N-terminal DUF1843 PF08898.5 KFX97958.1 - 0.26 11.3 9.5 8.9 6.4 0.1 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF1843) Semialdhyde_dhC PF02774.13 KFX97958.1 - 9.2 6.0 10.0 68 3.2 0.0 4.5 2 2 2 4 4 4 0 Semialdehyde dehydrogenase, dimerisation domain p450 PF00067.17 KFX97960.1 - 8.2e-52 176.2 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asparaginase_II PF06089.7 KFX97960.1 - 0.045 12.4 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 L-asparaginase II Peptidase_C48 PF02902.14 KFX97961.1 - 0.0003 20.4 0.0 0.00072 19.2 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AT_hook PF02178.14 KFX97961.1 - 0.047 13.3 3.9 0.28 10.9 2.7 2.4 1 0 0 1 1 1 0 AT hook motif PHD PF00628.24 KFX97961.1 - 0.066 12.9 8.5 0.13 11.9 5.9 1.5 1 0 0 1 1 1 0 PHD-finger Atg14 PF10186.4 KFX97961.1 - 0.42 9.5 6.3 3.7 6.3 4.2 2.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1978 PF09321.5 KFX97961.1 - 1.2 8.5 4.8 8.1 5.8 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) CENP-Q PF13094.1 KFX97961.1 - 1.4 8.9 8.0 0.09 12.7 1.2 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 KFX97961.1 - 5.5 6.8 8.4 0.66 9.8 1.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Serinc PF03348.10 KFX97964.1 - 1.7e-174 580.5 4.8 2.1e-174 580.2 3.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Adipogenin PF15202.1 KFX97964.1 - 0.29 11.0 2.7 18 5.2 0.1 3.0 2 0 0 2 2 2 0 Adipogenin DUF2254 PF10011.4 KFX97964.1 - 0.73 8.2 5.7 0.21 10.0 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) adh_short PF00106.20 KFX97965.1 - 6.8e-24 84.6 0.6 6.8e-24 84.6 0.4 2.2 2 1 0 2 2 2 1 short chain dehydrogenase MFS_1 PF07690.11 KFX97965.1 - 1.9e-17 62.9 27.0 1.9e-17 62.9 18.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KFX97965.1 - 4.4e-11 42.5 2.6 1e-10 41.3 1.8 1.6 1 0 0 1 1 1 1 Nodulin-like KR PF08659.5 KFX97965.1 - 1.8e-08 34.2 0.5 0.00032 20.4 0.0 2.6 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KFX97965.1 - 2.3e-06 27.5 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX97965.1 - 5.9e-05 22.6 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97965.1 - 0.0029 17.6 0.0 0.0063 16.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KFX97965.1 - 0.0031 16.4 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain PGAP1 PF07819.8 KFX97966.1 - 5.8e-88 294.2 0.0 7.8e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX97966.1 - 1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX97966.1 - 0.00065 19.6 0.3 0.0023 17.8 0.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX97966.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 KFX97966.1 - 0.028 13.6 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 KFX97966.1 - 0.057 12.1 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family p450 PF00067.17 KFX97968.1 - 2.6e-33 115.2 0.0 3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4 PF00097.20 KFX97971.1 - 0.00074 19.1 2.1 0.0015 18.1 1.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX97971.1 - 0.0015 18.1 0.3 0.003 17.2 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KFX97971.1 - 0.01 15.6 5.6 0.017 14.9 3.9 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KFX97971.1 - 0.011 15.7 3.9 0.021 14.8 2.7 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX97971.1 - 0.049 13.3 5.8 0.078 12.7 4.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain APH PF01636.18 KFX97972.1 - 1e-08 35.2 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX97972.1 - 0.032 13.7 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 KFX97972.1 - 0.061 12.4 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.16 KFX97973.1 - 9.7e-73 244.4 0.0 1.1e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_binding_2 PF13380.1 KFX97973.1 - 0.12 12.5 0.0 6.3 6.9 0.0 2.7 2 1 0 2 2 2 0 CoA binding domain Abhydrolase_5 PF12695.2 KFX97974.1 - 6.6e-12 45.3 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX97974.1 - 1.1e-11 45.0 0.1 2.7e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX97974.1 - 4.3e-05 22.8 0.0 0.043 13.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 KFX97974.1 - 0.00028 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KFX97974.1 - 0.0077 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX97974.1 - 0.013 14.6 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.8 KFX97974.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein CRISPR_Cse2 PF09485.5 KFX97974.1 - 0.048 13.7 0.0 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Thioesterase PF00975.15 KFX97974.1 - 0.084 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3715 PF12509.3 KFX97974.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Pyr_redox_3 PF13738.1 KFX97975.1 - 6.8e-29 101.3 0.0 1.8e-27 96.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX97975.1 - 1.2e-14 53.4 0.0 1.2e-12 46.7 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX97975.1 - 4.6e-11 42.5 0.0 4e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX97975.1 - 1.2e-07 31.0 0.2 0.00021 20.4 0.0 2.6 3 0 0 3 3 3 2 Thi4 family K_oxygenase PF13434.1 KFX97975.1 - 2.4e-07 29.9 0.0 0.00021 20.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX97975.1 - 4.4e-07 29.9 0.0 0.073 12.9 0.0 3.3 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX97975.1 - 9.4e-07 28.0 0.6 0.0041 16.0 0.1 3.7 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX97975.1 - 5.8e-05 22.9 0.3 1.8 8.3 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX97975.1 - 0.0002 21.7 0.1 0.081 13.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX97975.1 - 0.0011 19.0 0.0 0.17 11.9 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KFX97975.1 - 0.0016 17.4 0.0 0.47 9.3 0.0 3.5 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX97975.1 - 0.0018 17.2 0.1 0.23 10.2 0.2 2.8 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 KFX97975.1 - 0.0034 16.4 0.0 9.1 5.2 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KFX97975.1 - 0.021 13.7 1.3 2.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 KFX97977.1 - 3.2e-22 79.2 1.9 5.5e-22 78.4 1.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFX97977.1 - 2.4e-05 24.4 0.3 0.00022 21.2 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFX97977.1 - 3.4e-05 23.5 3.2 0.00036 20.2 2.2 2.0 1 1 0 1 1 1 1 KR domain DFP PF04127.10 KFX97977.1 - 0.0013 18.3 0.8 0.0043 16.6 0.1 1.8 1 1 1 2 2 2 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 KFX97977.1 - 0.0019 17.6 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX97977.1 - 0.0026 16.7 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KFX97977.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UPF0146 PF03686.8 KFX97977.1 - 0.089 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FA_hydroxylase PF04116.8 KFX97978.1 - 8.3e-15 55.1 10.4 8.3e-15 55.1 7.2 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3712 PF12505.3 KFX97979.1 - 7.7e-35 119.6 2.3 4.5e-34 117.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KFX97979.1 - 0.053 13.9 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein CRAL_TRIO PF00650.15 KFX97980.1 - 1.5e-42 144.7 0.0 3.3e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX97980.1 - 1.7e-09 37.6 0.9 3.7e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFX97980.1 - 4.2e-08 33.2 0.0 8.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_trans_1_3 PF13528.1 KFX97981.1 - 0.035 13.3 0.0 0.085 12.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 KFX97981.1 - 0.055 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Thioredoxin_4 PF13462.1 KFX97982.1 - 0.019 14.9 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin adh_short PF00106.20 KFX97983.1 - 1.6e-11 44.3 0.3 2.9e-11 43.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX97983.1 - 9.3e-08 32.1 0.2 1.4e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX97983.1 - 0.00032 20.4 0.3 0.00095 18.8 0.2 1.7 2 0 0 2 2 2 1 KR domain ApbA PF02558.11 KFX97983.1 - 0.00073 19.0 0.2 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX97983.1 - 0.0019 17.8 0.9 0.0037 16.9 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFX97983.1 - 0.071 12.1 0.2 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pec_lyase_C PF00544.14 KFX97984.1 - 6.7e-18 64.8 5.9 2.4e-17 63.0 4.1 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFX97984.1 - 0.00082 19.1 14.8 0.0028 17.4 5.9 2.5 1 1 1 2 2 2 2 Right handed beta helix region COesterase PF00135.23 KFX97985.1 - 2.7e-87 293.7 0.0 3.6e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Pectinesterase PF01095.14 KFX97985.1 - 1e-41 142.5 1.1 1.1e-40 139.1 0.7 2.2 2 0 0 2 2 2 1 Pectinesterase Abhydrolase_3 PF07859.8 KFX97985.1 - 4.7e-07 29.5 0.2 3e-06 26.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 KFX97985.1 - 0.058 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Pox_MCEL PF03291.11 KFX97999.1 - 1.3e-34 119.5 0.0 3.3e-17 62.3 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme zf-Nse PF11789.3 KFX98000.1 - 1.3e-15 56.6 0.0 2.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFX98000.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger IncA PF04156.9 KFX98000.1 - 0.19 11.3 4.0 0.33 10.5 2.8 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFX98000.1 - 9.6 5.1 9.7 18 4.2 6.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 MFS_1 PF07690.11 KFX98003.1 - 5.5e-43 147.0 29.6 5.5e-43 147.0 20.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX98003.1 - 3.1e-08 32.3 3.4 4.7e-08 31.6 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX98003.1 - 1.4e-07 30.4 25.9 1.9e-06 26.7 17.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MAPEG PF01124.13 KFX98004.1 - 2.1e-15 56.4 3.2 3e-15 55.9 2.2 1.2 1 0 0 1 1 1 1 MAPEG family DUF3433 PF11915.3 KFX98012.1 - 4.3e-18 65.2 14.3 1.6e-11 44.1 2.4 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Mo-co_dimer PF03404.11 KFX98013.1 - 2.8e-57 191.9 0.0 5.8e-57 190.9 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KFX98013.1 - 4.7e-48 162.8 0.0 1.1e-47 161.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KFX98013.1 - 2.3e-29 101.3 0.0 3.8e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFX98013.1 - 3.9e-25 88.5 0.0 1.1e-24 87.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KFX98013.1 - 1.4e-21 76.1 0.0 2.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFX98013.1 - 0.0023 17.8 0.1 0.17 11.7 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 KFX98014.1 - 2.1e-31 108.4 0.0 4.3e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KFX98014.1 - 2e-29 102.9 0.1 4e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KFX98014.1 - 5.2e-26 91.2 14.9 8e-26 90.5 10.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Rieske_2 PF13806.1 KFX98014.1 - 1e-15 57.2 0.0 2.1e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 KFX98014.1 - 1.4e-15 57.4 0.8 1.5e-13 50.9 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 KFX98014.1 - 3.3e-12 46.2 4.1 2e-11 43.7 2.8 2.2 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 KFX98014.1 - 1.1e-09 37.7 0.2 3.1e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KFX98014.1 - 4.3e-09 35.8 0.0 2.7e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 KFX98014.1 - 4.8e-05 23.5 0.0 0.0019 18.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX98014.1 - 0.0084 15.0 1.1 7.4 5.3 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX98014.1 - 0.011 15.5 2.0 3.3 7.4 0.0 3.2 3 1 0 4 4 4 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFX98014.1 - 0.07 12.0 0.0 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 KFX98014.1 - 0.43 9.3 2.7 6.8 5.4 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.17 KFX98014.1 - 0.51 9.1 3.1 29 3.3 1.4 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A GST_N_3 PF13417.1 KFX98015.1 - 6.5e-14 51.9 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX98015.1 - 3.5e-13 49.3 0.0 9e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX98015.1 - 7.2e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX98015.1 - 4e-09 36.3 0.1 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX98015.1 - 9.2e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX98015.1 - 3.6e-05 24.1 0.1 5.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KFX98015.1 - 0.095 13.0 0.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 MetRS-N binding domain Lipase_GDSL PF00657.17 KFX98016.1 - 1.7e-09 37.8 1.4 2.4e-09 37.4 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX98016.1 - 2e-09 37.8 1.5 3e-09 37.2 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family VWA_2 PF13519.1 KFX98017.1 - 5.7e-06 26.5 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX98017.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MFS_1 PF07690.11 KFX98018.1 - 2.2e-36 125.2 60.5 1.6e-34 119.1 41.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KFX98019.1 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX98019.1 - 7.9e-07 29.1 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX98019.1 - 3.7e-06 27.0 0.3 7.2e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX98019.1 - 0.0093 15.8 0.2 1.7 8.4 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KFX98019.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FSH1 PF03959.8 KFX98021.1 - 1.8e-17 63.5 0.0 2.1e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) RPE65 PF03055.10 KFX98022.1 - 2.9e-95 319.6 0.0 4.1e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PCI PF01399.22 KFX98022.1 - 8.7e-20 71.0 0.2 2.9e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain Synaptobrevin PF00957.16 KFX98022.1 - 0.49 10.0 3.1 1.6 8.4 0.6 2.5 2 0 0 2 2 2 0 Synaptobrevin CAP_N PF01213.14 KFX98034.1 - 3.2e-87 292.7 23.3 5e-67 226.4 5.0 2.3 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KFX98034.1 - 7.1e-59 197.6 1.0 9.9e-59 197.2 0.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribonuclease_3 PF00636.21 KFX98036.1 - 3.7e-09 37.0 0.0 9.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFX98036.1 - 2e-08 34.2 0.0 0.00031 20.7 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KFX98036.1 - 0.00016 22.2 0.1 0.00049 20.6 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif La PF05383.12 KFX98037.1 - 1.2e-12 47.3 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFX98037.1 - 9.9e-09 34.7 0.2 2.2e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX98037.1 - 4.7e-08 32.8 0.0 8.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2946 PF11162.3 KFX98038.1 - 0.067 13.3 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) S4 PF01479.20 KFX98039.1 - 4.1e-17 61.3 0.0 7e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KFX98039.1 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain FancD2 PF14631.1 KFX98039.1 - 0.012 12.7 2.4 0.015 12.4 1.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.7 KFX98039.1 - 0.3 10.9 4.6 0.53 10.1 3.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.15 KFX98039.1 - 1.2 6.9 8.4 1.7 6.4 5.8 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF3323 PF11796.3 KFX98039.1 - 1.3 8.3 13.7 0.081 12.2 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) INCENP_ARK-bind PF03941.10 KFX98040.1 - 7.3e-16 57.7 0.0 3.1e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region HC2 PF07382.6 KFX98040.1 - 0.0016 18.3 25.5 0.0016 18.3 17.7 3.2 3 0 0 3 3 3 1 Histone H1-like nucleoprotein HC2 Phosphoesterase PF04185.9 KFX98041.1 - 5.1e-66 223.3 1.1 9.8e-66 222.4 0.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.11 KFX98042.1 - 1.7e-29 102.6 58.8 1e-28 100.1 40.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98042.1 - 2.2e-07 29.8 17.6 2.2e-07 29.8 12.2 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3435 PF11917.3 KFX98048.1 - 0.0014 17.4 0.1 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) HTH_23 PF13384.1 KFX98060.1 - 0.00019 20.9 0.2 0.00035 20.1 0.2 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KFX98060.1 - 0.00071 20.3 5.6 0.25 12.1 0.4 2.6 1 1 1 2 2 2 2 Homeodomain-like domain DUF1421 PF07223.6 KFX98060.1 - 0.012 15.4 15.2 0.013 15.3 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) HTH_38 PF13936.1 KFX98060.1 - 0.041 13.4 1.3 0.12 11.9 0.9 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain DEAD PF00270.24 KFX98061.1 - 7.5e-26 90.6 0.2 6.2e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX98061.1 - 1.4e-21 76.1 0.2 3.2e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX98061.1 - 0.00019 21.3 0.7 0.00035 20.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFX98061.1 - 0.00049 18.9 0.4 0.00083 18.2 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ParA PF10609.4 KFX98061.1 - 0.15 11.9 0.2 0.43 10.4 0.2 1.7 1 0 0 1 1 1 0 ParA/MinD ATPase like DDHD PF02862.12 KFX98061.1 - 9.5 5.9 7.4 46 3.6 0.0 2.5 2 0 0 2 2 2 0 DDHD domain ADH_N PF08240.7 KFX98062.1 - 7.5e-28 96.4 2.5 1.5e-27 95.5 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ATP-synt_G PF04718.10 KFX98062.1 - 3.1e-27 95.2 0.4 1.2e-26 93.3 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_zinc_N PF00107.21 KFX98062.1 - 2.6e-15 56.1 0.1 8.1e-15 54.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX98063.1 - 2.6e-47 160.2 0.0 1e-46 158.3 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX98063.1 - 1.7e-06 27.5 0.0 3.1e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 KFX98063.1 - 0.052 12.9 0.1 0.15 11.4 0.1 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KFX98063.1 - 0.099 12.3 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KFX98063.1 - 0.16 11.6 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KFX98063.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Glyco_hydro_2_N PF02837.13 KFX98064.1 - 2.2e-09 37.0 0.8 7.6e-09 35.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX98064.1 - 3.1e-08 34.0 0.3 1.1e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFX98064.1 - 4.1e-05 22.6 0.0 8.3e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF402 PF04167.8 KFX98064.1 - 0.011 15.5 1.0 0.13 12.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF402) DUF3292 PF11696.3 KFX98077.1 - 2.6e-230 765.7 0.0 3.6e-230 765.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) p450 PF00067.17 KFX98077.1 - 8.3e-27 93.8 0.0 4.5e-26 91.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.4 KFX98078.1 - 9.2e-14 51.2 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase AMP-binding PF00501.23 KFX98079.1 - 1.3e-82 277.4 0.0 2.1e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX98079.1 - 0.019 15.9 0.1 0.045 14.6 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KFX98080.1 - 3.3e-61 206.0 6.6 4.2e-30 104.8 0.4 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KFX98080.1 - 2.8e-31 107.4 0.0 5.8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KFX98080.1 - 9.8e-30 103.5 2.7 4.9e-14 52.4 0.1 2.6 3 0 0 3 3 3 2 KR domain MaoC_dehydrat_N PF13452.1 KFX98080.1 - 1.2e-10 41.2 0.0 6.2e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KFX98080.1 - 4.7e-05 22.5 0.2 0.00058 18.9 0.0 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 KFX98080.1 - 0.015 15.6 0.2 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DUF2099 PF09872.4 KFX98080.1 - 0.11 11.4 0.3 0.55 9.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) Eno-Rase_NADH_b PF12242.3 KFX98080.1 - 0.54 10.0 3.9 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_17 PF13207.1 KFX98082.1 - 0.0011 19.8 0.3 0.0047 17.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFX98082.1 - 0.0029 16.6 0.0 0.0054 15.7 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain ArgK PF03308.11 KFX98082.1 - 0.003 16.3 0.0 0.0048 15.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 KFX98082.1 - 0.0053 17.0 0.0 0.015 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX98082.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 KFX98082.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 KFX98082.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KFX98082.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KFX98082.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.1 KFX98091.1 - 9.3e-25 87.8 0.0 6.5e-24 85.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX98091.1 - 7.8e-17 61.2 0.2 1.1e-12 47.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFX98091.1 - 1.4e-15 56.5 0.0 3.9e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX98091.1 - 2.3e-12 47.2 0.0 4.5e-09 36.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX98091.1 - 1.8e-10 41.0 0.2 1.2e-05 25.4 0.0 3.2 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFX98091.1 - 1.3e-09 38.3 0.1 0.00097 19.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KFX98091.1 - 3.8e-08 33.6 0.6 0.031 14.7 0.1 3.4 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KFX98091.1 - 4.2e-07 29.1 0.8 0.0047 15.8 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX98091.1 - 5.6e-07 29.5 0.1 1.7e-05 24.7 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KFX98091.1 - 1.1e-06 27.8 0.0 0.0039 16.3 0.0 2.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KFX98091.1 - 1.4e-06 27.4 0.9 0.014 14.3 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX98091.1 - 1.9e-06 27.7 1.5 0.04 13.7 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFX98091.1 - 5.8e-06 25.6 0.3 1.6e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 KFX98091.1 - 1.9e-05 24.6 0.1 0.25 11.3 0.0 3.0 3 0 0 3 3 3 2 TrkA-N domain ThiF PF00899.16 KFX98091.1 - 0.00016 21.5 1.1 0.4 10.5 0.2 3.0 3 0 0 3 3 3 2 ThiF family HI0933_like PF03486.9 KFX98091.1 - 0.00023 19.7 0.7 0.0065 14.9 0.1 3.0 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.1 KFX98091.1 - 0.00032 20.9 0.0 0.13 12.5 0.0 2.7 3 0 0 3 3 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KFX98091.1 - 0.0014 18.3 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KFX98091.1 - 0.0037 16.8 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFX98091.1 - 0.0063 15.4 0.3 0.0063 15.4 0.2 2.8 3 1 0 4 4 4 1 FAD binding domain GIDA PF01134.17 KFX98091.1 - 0.016 14.1 1.6 2.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A CPSase_L_chain PF00289.17 KFX98091.1 - 0.017 15.2 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Malic_M PF03949.10 KFX98091.1 - 0.02 14.4 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Thi4 PF01946.12 KFX98091.1 - 0.023 13.7 1.4 1.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Thi4 family IlvN PF07991.7 KFX98091.1 - 0.024 13.9 0.0 6.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 KFX98091.1 - 0.063 13.5 0.0 0.73 10.1 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.18 KFX98091.1 - 0.11 12.2 0.5 4.2 7.0 0.0 2.9 4 0 0 4 4 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Zn_clus PF00172.13 KFX98092.1 - 7.3e-09 35.3 5.8 1.3e-08 34.5 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX98092.1 - 1.6e-05 23.7 2.8 4.1e-05 22.3 1.9 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain WXG100 PF06013.7 KFX98092.1 - 0.12 12.3 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG TPR_1 PF00515.23 KFX98098.1 - 2.4e-21 74.3 2.8 2.8e-05 23.5 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFX98098.1 - 1e-18 66.6 7.3 7.6e-08 31.9 0.5 4.7 3 1 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 KFX98098.1 - 3.1e-16 57.8 11.9 0.0036 17.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98098.1 - 2.2e-15 55.1 1.0 8.4e-05 22.0 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX98098.1 - 8.7e-13 48.0 11.1 0.0041 17.0 1.1 4.8 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98098.1 - 4.2e-10 39.3 12.0 0.0074 16.8 0.0 5.7 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 KFX98098.1 - 2.3e-09 36.9 12.0 0.00043 20.0 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98098.1 - 3.1e-09 37.2 15.2 5.1e-06 27.0 0.6 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX98098.1 - 3.8e-09 35.6 14.4 0.0082 15.8 0.0 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 KFX98098.1 - 2.9e-06 27.3 0.7 0.014 15.4 0.3 2.6 2 1 1 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 KFX98098.1 - 7.1e-05 22.6 5.7 0.00087 19.1 0.1 3.3 2 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 KFX98098.1 - 0.00016 21.9 3.6 5.6 7.3 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFX98098.1 - 0.00034 20.8 14.1 6.1 7.5 0.2 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98098.1 - 0.0015 18.5 0.3 0.85 9.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFX98098.1 - 0.002 17.2 7.4 0.0024 17.0 2.1 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFX98098.1 - 0.019 14.8 15.7 0.11 12.5 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF2424 PF10340.4 KFX98098.1 - 0.034 12.7 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MIT PF04212.13 KFX98098.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.5 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain AAA_16 PF13191.1 KFX98111.1 - 1.6e-05 24.9 0.5 0.00013 22.0 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 KFX98111.1 - 5.4e-05 22.5 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 KFX98111.1 - 8.9e-05 22.6 0.0 0.00041 20.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 KFX98111.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein FHA PF00498.21 KFX98113.1 - 7.2e-12 45.2 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 KFX98113.1 - 0.0053 15.2 24.1 0.006 15.1 16.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 GRP PF07172.6 KFX98113.1 - 0.53 10.7 17.1 0.11 12.9 9.2 1.9 2 0 0 2 2 2 0 Glycine rich protein family MFS_1 PF07690.11 KFX98114.1 - 1.1e-27 96.7 29.8 1.1e-27 96.7 20.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 KFX98114.1 - 0.00017 20.4 1.7 0.0086 14.8 0.0 2.6 1 1 1 2 2 2 2 BT1 family PGPGW PF09656.5 KFX98114.1 - 0.093 12.0 0.3 0.093 12.0 0.2 2.9 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) DUF3633 PF12315.3 KFX98114.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) UL73_N PF12522.3 KFX98114.1 - 8.7 5.9 14.0 18 4.9 9.7 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Sugar_tr PF00083.19 KFX98116.1 - 1.1e-69 235.2 26.9 1.4e-69 234.8 18.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98116.1 - 2.7e-15 55.9 26.9 2.7e-15 55.9 18.6 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 KFX98117.1 - 3.2e-51 174.5 0.0 7.2e-51 173.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KFX98117.1 - 2.1e-11 44.0 0.0 4.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KFX98117.1 - 0.0031 16.8 0.0 0.0071 15.6 0.0 1.5 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFX98117.1 - 0.066 13.0 1.7 0.67 10.0 0.2 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Fungal_trans PF04082.13 KFX98118.1 - 2.3e-07 29.9 0.7 2.3e-07 29.9 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3656 PF12392.3 KFX98118.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Collagenase DUF2961 PF11175.3 KFX98119.1 - 9.1e-86 287.0 4.3 1.2e-85 286.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Adenylsucc_synt PF00709.16 KFX98125.1 - 2.6e-159 530.4 0.1 2.9e-159 530.2 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Histone PF00125.19 KFX98126.1 - 2.2e-08 34.0 0.1 3.4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFX98126.1 - 6e-05 23.1 0.4 0.00023 21.2 0.3 1.8 1 1 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KFX98126.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 KFX98126.1 - 0.0096 15.8 0.1 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) ATP_bind_4 PF01902.12 KFX98126.1 - 0.043 13.1 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 ATP-binding region CBFD_NFYB_HMF PF00808.18 KFX98126.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 KFX98126.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Svf1 PF08622.5 KFX98127.1 - 2.4e-123 411.3 0.3 3.1e-123 410.9 0.2 1.1 1 0 0 1 1 1 1 Svf1-like Ribosomal_L11_N PF03946.9 KFX98128.1 - 1e-26 92.1 0.1 3e-26 90.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KFX98128.1 - 1.1e-23 83.1 0.2 1.8e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain GTP_EFTU PF00009.22 KFX98133.1 - 1.6e-56 190.7 0.0 2.4e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFX98133.1 - 2.3e-37 127.1 0.0 6.3e-37 125.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFX98133.1 - 1.4e-15 57.1 3.4 1.4e-15 57.1 2.4 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX98133.1 - 0.00064 19.6 0.2 0.0023 17.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KFX98133.1 - 0.002 17.7 1.5 0.002 17.7 1.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GLE1 PF07817.8 KFX98144.1 - 9.8e-25 86.9 0.0 1.5e-23 83.0 0.0 2.3 1 1 0 1 1 1 1 GLE1-like protein CAF-1_p150 PF11600.3 KFX98144.1 - 0.023 14.0 0.6 0.023 14.0 0.4 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3375 PF11855.3 KFX98144.1 - 0.68 8.6 9.3 1.5 7.5 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) PAT1 PF09770.4 KFX98144.1 - 7.5 4.6 26.0 10 4.2 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNB PF00773.14 KFX98145.1 - 7.9e-85 284.9 0.0 1.7e-84 283.9 0.0 1.6 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 KFX98145.1 - 0.33 10.2 0.1 0.71 9.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Solute_trans_a PF03619.11 KFX98150.1 - 7.8e-82 274.6 22.8 8.9e-82 274.4 15.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PBP PF01161.15 KFX98153.1 - 0.12 12.2 2.4 0.11 12.3 1.3 1.3 1 1 0 1 1 1 0 Phosphatidylethanolamine-binding protein Pap_E4 PF02711.9 KFX98153.1 - 6.4 7.6 9.8 0.51 11.1 3.7 1.5 2 0 0 2 2 2 0 E4 protein SbcCD_C PF13558.1 KFX98164.1 - 9e-12 44.7 0.0 2.6e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KFX98164.1 - 4e-11 43.6 117.7 1.1 9.5 66.6 7.1 1 1 1 2 2 1 1 AAA domain AAA_13 PF13166.1 KFX98164.1 - 4.5e-11 41.9 115.5 0.00044 18.8 0.0 6.6 3 1 2 6 6 6 4 AAA domain SMC_N PF02463.14 KFX98164.1 - 1.2e-09 37.7 29.0 1.8e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFX98164.1 - 3.6e-06 26.2 0.0 4.3e-05 22.7 0.0 5.7 3 1 1 5 5 2 2 AAA ATPase domain AAA_21 PF13304.1 KFX98164.1 - 6.1e-06 26.3 13.3 0.032 14.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFX98164.1 - 0.00086 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.9 KFX98164.1 - 0.0041 16.5 0.7 0.0041 16.5 0.5 5.2 5 0 0 5 5 5 1 Rad50 zinc hook motif MobB PF03205.9 KFX98164.1 - 0.013 15.2 0.1 0.07 12.8 0.1 2.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFX98164.1 - 0.088 13.1 0.1 0.088 13.1 0.0 7.1 2 1 2 5 5 3 0 ABC transporter DUF948 PF06103.6 KFX98164.1 - 0.15 11.9 0.1 0.15 11.9 0.0 6.4 7 1 1 8 8 8 0 Bacterial protein of unknown function (DUF948) GATA PF00320.22 KFX98165.1 - 4e-15 54.8 4.3 7.7e-15 53.9 3.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 KFX98165.1 - 2.1e-14 53.3 0.0 4.8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KFX98165.1 - 1e-12 47.8 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KFX98165.1 - 1.8e-10 41.1 0.0 4.6e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 KFX98165.1 - 5.4e-08 32.7 0.0 9.4e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 KFX98165.1 - 2e-06 27.7 0.0 3.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PHY PF00360.15 KFX98165.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region DUF3742 PF12553.3 KFX98165.1 - 0.15 12.5 0.7 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) PPP4R2 PF09184.6 KFX98167.1 - 8.3e-07 28.8 3.2 1.3e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 PPP4R2 tRNA-synt_2 PF00152.15 KFX98168.1 - 2e-78 263.5 0.0 2.5e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFX98168.1 - 2.2e-09 37.0 0.2 3.9e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFX98168.1 - 4.7e-06 25.9 0.0 0.0038 16.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KFX98168.1 - 0.054 13.0 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 KFX98169.1 - 2e-22 78.2 0.8 2.4e-22 77.9 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 KFX98169.1 - 0.0053 16.3 1.4 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase PG_binding_1 PF01471.13 KFX98170.1 - 9.6e-05 22.2 0.3 0.24 11.3 0.0 3.5 3 1 0 3 3 3 2 Putative peptidoglycan binding domain Spc7 PF08317.6 KFX98170.1 - 0.19 10.3 6.5 0.37 9.3 4.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KFX98170.1 - 0.4 10.5 1.2 0.76 9.5 0.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 KFX98170.1 - 0.82 9.8 8.2 5.2 7.2 4.1 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 KFX98170.1 - 0.86 7.9 6.0 1.2 7.4 4.2 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 KFX98170.1 - 0.89 9.0 7.1 1.7 8.0 4.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IncA PF04156.9 KFX98170.1 - 1.5 8.3 7.5 3.6 7.1 5.2 1.6 1 0 0 1 1 1 0 IncA protein CLTH PF10607.4 KFX98171.1 - 1.6e-22 79.7 0.1 3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain ECH PF00378.15 KFX98173.1 - 3.8e-40 137.5 0.0 4.7e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Sugar_tr PF00083.19 KFX98174.1 - 3.8e-54 183.9 8.1 4.5e-54 183.7 5.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98174.1 - 2.5e-20 72.5 11.8 3e-20 72.2 8.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX98174.1 - 0.00033 19.1 2.2 0.00033 19.1 1.5 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 KFX98174.1 - 0.0098 14.1 4.4 0.014 13.6 3.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFX98174.1 - 0.035 12.1 3.2 0.045 11.8 0.0 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 KFX98174.1 - 0.1 12.6 1.4 0.32 11.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Rick_17kDa_Anti PF05433.10 KFX98174.1 - 0.43 10.2 3.9 1.1 8.9 2.7 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain ADH_N PF08240.7 KFX98175.1 - 3.2e-30 104.0 2.0 6.3e-30 103.1 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX98175.1 - 1.2e-23 83.1 0.3 1.8e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX98175.1 - 7e-05 23.7 0.0 0.00015 22.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFX98175.1 - 0.0069 15.7 0.2 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 KFX98175.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KFX98175.1 - 0.04 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 KFX98175.1 - 0.096 11.8 2.8 0.24 10.5 1.9 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region FGGY_C PF02782.11 KFX98176.1 - 1.2e-47 162.1 0.1 1.7e-47 161.6 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFX98176.1 - 1.3e-24 86.8 0.3 5.1e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFX98176.1 - 0.0018 17.6 0.1 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 KFX98176.1 - 0.0019 17.5 0.0 0.0097 15.2 0.0 1.9 2 0 0 2 2 2 1 Hexokinase TPR_10 PF13374.1 KFX98191.1 - 1.9e-60 199.1 38.0 1.4e-06 28.0 0.1 10.7 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_12 PF13424.1 KFX98191.1 - 3.9e-57 190.1 40.4 2.1e-12 46.8 0.5 6.6 1 1 3 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98191.1 - 3e-33 111.0 0.1 0.1 12.4 0.0 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98191.1 - 3.5e-28 95.2 5.8 0.35 10.9 0.0 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98191.1 - 2e-23 80.7 21.8 0.019 15.5 0.2 11.1 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98191.1 - 1.1e-22 80.1 23.9 6.7e-05 23.4 0.4 7.7 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.1 KFX98191.1 - 1.3e-22 79.8 28.5 0.00016 21.9 0.1 10.0 2 1 8 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFX98191.1 - 1.8e-22 78.7 19.3 8.5e-05 22.1 0.1 6.5 4 1 3 7 7 7 7 TPR repeat TPR_7 PF13176.1 KFX98191.1 - 3.4e-20 70.1 15.2 0.15 11.9 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.23 KFX98191.1 - 9.3e-20 69.3 3.6 2.5 7.8 0.0 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFX98191.1 - 7e-19 66.9 0.7 6.1 7.5 0.0 10.7 10 0 0 10 10 10 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX98191.1 - 8.5e-19 67.4 25.1 0.002 18.2 1.4 9.0 1 1 7 8 8 8 7 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KFX98191.1 - 1e-18 67.2 47.1 0.035 14.2 0.5 11.0 3 1 9 12 12 11 8 Tetratricopeptide repeat PPR PF01535.15 KFX98191.1 - 8.6e-15 53.6 0.1 8.4 6.6 0.0 9.7 11 0 0 11 11 9 0 PPR repeat TPR_17 PF13431.1 KFX98191.1 - 1.2e-13 50.0 22.1 2.3 8.6 0.1 9.9 10 0 0 10 10 9 3 Tetratricopeptide repeat PPR_1 PF12854.2 KFX98191.1 - 2e-10 39.9 4.6 17 4.9 0.0 9.3 10 0 0 10 10 9 0 PPR repeat NB-ARC PF00931.17 KFX98191.1 - 7.1e-07 28.3 0.0 1.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PPR_3 PF13812.1 KFX98191.1 - 2.5e-06 27.3 2.7 9.1 6.8 0.0 7.6 7 0 0 7 7 7 0 Pentatricopeptide repeat domain ATP13 PF12921.2 KFX98191.1 - 3.5e-06 26.3 3.9 15 4.9 0.0 7.8 2 2 5 8 8 8 0 Mitochondrial ATPase expression Aida_N PF08910.5 KFX98191.1 - 3.7e-06 27.1 5.9 1.8 8.8 0.0 7.5 1 1 8 9 9 9 1 Aida N-terminus Abhydrolase_6 PF12697.2 KFX98191.1 - 3e-05 24.0 1.0 0.00018 21.4 0.0 2.6 3 0 0 3 3 2 1 Alpha/beta hydrolase family Fer2_2 PF01799.15 KFX98191.1 - 5.6e-05 22.9 0.6 6.3 6.7 0.0 6.3 3 2 5 8 8 8 0 [2Fe-2S] binding domain AAA_22 PF13401.1 KFX98191.1 - 0.00015 21.9 0.2 0.0014 18.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain Abhydrolase_9 PF10081.4 KFX98191.1 - 0.00051 18.8 0.2 0.015 14.0 0.0 3.1 3 1 1 4 4 4 1 Alpha/beta-hydrolase family WbqC PF08889.6 KFX98191.1 - 0.0027 17.2 6.9 23 4.3 0.1 5.0 2 2 2 5 5 5 0 WbqC-like protein family LCAT PF02450.10 KFX98191.1 - 0.0046 15.9 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 KFX98191.1 - 0.015 14.8 0.0 0.047 13.2 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX98191.1 - 0.028 14.1 0.0 0.12 12.1 0.0 2.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_3 PF07720.7 KFX98191.1 - 0.029 14.1 4.9 4 7.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFX98191.1 - 0.06 13.8 23.5 8.5 7.1 0.1 8.4 8 0 0 8 8 7 0 Tetratricopeptide repeat AAA PF00004.24 KFX98191.1 - 0.11 12.6 0.0 0.58 10.3 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MurB_C PF02873.11 KFX98191.1 - 0.27 11.0 22.0 1.4 8.6 0.3 6.2 1 1 4 5 5 5 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain EF1_GNE PF00736.14 KFX98192.1 - 1.3e-30 104.8 2.0 2.6e-30 103.9 1.4 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFX98192.1 - 1.4e-14 53.8 6.6 4.1e-14 52.4 4.6 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KFX98192.1 - 0.0041 17.5 0.0 0.01 16.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX98192.1 - 0.014 15.4 0.2 0.049 13.6 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_transf_92 PF01697.22 KFX98205.1 - 2.9e-07 30.0 1.1 1.8e-06 27.4 0.7 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 KFX98205.1 - 3e-07 30.6 1.2 6e-07 29.7 0.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.21 KFX98205.1 - 0.0079 15.9 0.0 0.13 11.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 EI24 PF07264.6 KFX98206.1 - 3.9e-07 29.7 7.8 7.7e-07 28.7 5.4 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Picorna_P3A PF06363.6 KFX98206.1 - 0.14 12.1 0.8 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Picornaviridae P3A protein FMN_dh PF01070.13 KFX98207.1 - 1.8e-115 385.6 0.0 2.5e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Methyltransf_23 PF13489.1 KFX98207.1 - 5.3e-09 35.9 0.0 9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX98207.1 - 8.7e-08 32.7 0.0 1.7e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX98207.1 - 3e-05 24.4 0.0 7.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NMO PF03060.10 KFX98207.1 - 4e-05 22.9 3.6 6.5e-05 22.2 2.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Methyltransf_11 PF08241.7 KFX98207.1 - 4.5e-05 23.8 0.0 9.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX98207.1 - 0.00013 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Glu_synthase PF01645.12 KFX98207.1 - 0.00057 18.9 0.3 0.001 18.0 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFX98207.1 - 0.00061 18.7 1.6 0.0011 17.8 0.7 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFX98207.1 - 0.00092 18.3 0.3 0.18 10.8 0.1 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Methyltransf_25 PF13649.1 KFX98207.1 - 0.00095 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain His_biosynth PF00977.16 KFX98207.1 - 0.0015 17.8 0.2 0.074 12.3 0.0 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein MTS PF05175.9 KFX98207.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain IGPS PF00218.16 KFX98207.1 - 0.048 12.6 0.4 0.26 10.3 0.1 2.2 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Ubie_methyltran PF01209.13 KFX98207.1 - 0.082 11.9 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF3632 PF12311.3 KFX98208.1 - 1.1e-21 77.4 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MFS_1 PF07690.11 KFX98209.1 - 7.5e-49 166.3 39.4 4.1e-47 160.6 27.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX98209.1 - 2.4e-12 45.8 20.2 3.3e-12 45.4 14.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PgaD PF13994.1 KFX98209.1 - 2.2 7.7 10.2 0.14 11.6 0.4 2.7 2 0 0 2 2 2 0 PgaD-like protein DFP PF04127.10 KFX98210.1 - 2.5e-13 50.0 0.0 1.9e-05 24.3 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Rick_17kDa_Anti PF05433.10 KFX98212.1 - 0.00025 20.6 17.0 0.00025 20.6 11.8 2.0 1 1 2 3 3 3 3 Glycine zipper 2TM domain SR-25 PF10500.4 KFX98212.1 - 0.064 12.7 8.3 0.079 12.4 5.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KFX98212.1 - 0.39 10.7 11.0 0.48 10.4 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Gly-zipper_OmpA PF13436.1 KFX98212.1 - 0.72 9.5 9.0 1.1 8.9 6.2 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain BLVR PF06375.6 KFX98212.1 - 1.5 8.6 9.9 1.8 8.4 6.9 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) HlyIII PF03006.15 KFX98213.1 - 1e-59 201.6 18.9 1.2e-59 201.4 13.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 KFX98213.1 - 0.66 9.9 3.3 0.99 9.4 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) NADH-u_ox-rdase PF10785.4 KFX98213.1 - 3.4 7.9 10.1 2.9 8.1 1.3 3.2 4 1 1 5 5 5 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit zf-C2HC5 PF06221.8 KFX98214.1 - 2.6e-21 75.1 4.0 4e-21 74.5 2.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Aminotran_5 PF00266.14 KFX98215.1 - 6e-21 74.6 0.0 7.4e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFX98215.1 - 0.00045 19.2 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SIR2 PF02146.12 KFX98216.1 - 2.1e-27 96.0 0.0 3.1e-09 36.8 0.0 3.2 3 0 0 3 3 3 3 Sir2 family TPP_enzyme_M PF00205.17 KFX98216.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Beta-lactamase PF00144.19 KFX98218.1 - 1.2e-28 100.1 0.5 3.3e-28 98.6 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase PHP PF02811.14 KFX98219.1 - 6.4e-05 22.8 0.0 9.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 PHP domain MFS_1 PF07690.11 KFX98220.1 - 3.9e-53 180.4 16.9 3.9e-53 180.4 11.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98220.1 - 5.7e-09 35.0 8.7 5.7e-09 35.0 6.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFX98220.1 - 0.00038 18.7 5.1 0.00077 17.7 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KFX98220.1 - 0.0011 17.7 1.2 0.0011 17.7 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF791) OATP PF03137.15 KFX98220.1 - 0.026 12.6 5.3 0.065 11.2 1.6 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPR_11 PF13414.1 KFX98221.1 - 5.8e-11 41.8 6.0 3.5e-06 26.5 0.0 5.2 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 KFX98221.1 - 3.8e-06 27.4 2.0 2.6e-05 24.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98221.1 - 1.5e-05 24.5 8.9 0.012 15.4 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98221.1 - 9.1e-05 22.7 2.1 3.9 8.3 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX98221.1 - 0.00033 20.5 3.4 0.0028 17.5 0.1 3.9 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98221.1 - 0.00036 20.5 0.5 0.9 9.8 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX98221.1 - 0.00086 18.8 0.2 2.4 7.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98221.1 - 0.00089 18.8 1.0 3.3 7.7 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX98221.1 - 0.036 13.8 0.2 1 9.3 0.0 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 KFX98223.1 - 8.2e-85 284.9 0.0 1.6e-84 283.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.4 KFX98223.1 - 1.8e-17 62.9 1.1 1.9e-16 59.6 0.0 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.4 KFX98223.1 - 0.09 12.9 4.8 0.41 10.8 2.8 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CAP_N PF01213.14 KFX98224.1 - 2.6 7.2 7.6 4 6.6 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TRI12 PF06609.8 KFX98232.1 - 9.1e-99 331.2 25.5 1.2e-98 330.9 17.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX98232.1 - 1.2e-18 66.9 50.8 1.2e-18 66.9 35.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98232.1 - 4e-07 28.9 17.0 4e-07 28.9 11.8 3.5 2 2 1 3 3 3 1 Sugar (and other) transporter DUF3040 PF11239.3 KFX98232.1 - 0.09 12.8 0.1 0.09 12.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF4097 PF13349.1 KFX98232.1 - 2.3 7.7 6.0 0.15 11.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Pyr_redox_3 PF13738.1 KFX98233.1 - 1e-22 81.1 0.1 1.1e-20 74.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX98233.1 - 7.9e-08 30.9 0.0 3.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 KFX98233.1 - 8.2e-08 32.4 0.0 0.0003 20.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 KFX98233.1 - 5.4e-07 28.8 0.0 0.02 13.8 0.0 3.5 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX98233.1 - 1.2e-06 28.4 0.1 6.6e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX98233.1 - 3e-05 23.8 0.3 0.11 12.2 0.1 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 KFX98233.1 - 0.00025 20.0 1.7 0.46 9.3 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX98233.1 - 0.002 17.0 0.0 0.022 13.6 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 KFX98233.1 - 0.016 15.4 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KFX98233.1 - 0.047 12.5 0.0 0.094 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 KFX98233.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 KFX98233.1 - 0.23 11.2 1.9 0.66 9.7 0.3 2.3 2 0 0 2 2 2 0 ThiF family ADH_N PF08240.7 KFX98234.1 - 1.2e-20 73.2 3.7 2.9e-18 65.6 1.3 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX98234.1 - 1.4e-17 63.4 0.7 2.6e-17 62.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX98234.1 - 1.9e-12 48.1 0.3 4.7e-12 46.9 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KFX98234.1 - 0.0062 16.3 0.3 0.015 15.1 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Qn_am_d_aII PF14930.1 KFX98234.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II 2-Hacid_dh_C PF02826.14 KFX98234.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GST_C_3 PF14497.1 KFX98237.1 - 1.5e-10 41.4 0.0 2.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX98237.1 - 2.3e-05 24.1 0.2 6.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX98237.1 - 0.0031 17.7 0.1 0.082 13.1 0.1 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 KFX98238.1 - 0.0064 16.1 0.0 0.025 14.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KFX98238.1 - 0.56 9.9 4.4 36 4.1 0.1 3.7 3 0 0 3 3 3 0 F-box domain Acetyltransf_7 PF13508.1 KFX98239.1 - 2.7e-06 27.4 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX98239.1 - 3.6e-06 27.0 0.0 7.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX98239.1 - 1.6e-05 24.7 0.3 0.0025 17.6 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX98239.1 - 4.2e-05 23.4 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 KFX98239.1 - 0.032 14.1 0.0 0.077 12.8 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 KFX98239.1 - 0.075 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 KFX98239.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Myb_DNA-binding PF00249.26 KFX98240.1 - 5.9e-05 23.0 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HeLo PF14479.1 KFX98240.1 - 0.48 10.1 6.2 0.46 10.2 0.8 2.8 2 1 0 2 2 2 0 Prion-inhibition and propagation TRAM_LAG1_CLN8 PF03798.11 KFX98241.1 - 1.1e-33 116.5 12.2 1.1e-33 116.5 8.4 1.5 2 0 0 2 2 2 1 TLC domain USP7_ICP0_bdg PF12436.3 KFX98242.1 - 9.9e-43 146.1 0.1 1.6e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 KFX98242.1 - 9.9e-40 136.3 0.0 1.6e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX98242.1 - 1e-19 71.1 0.0 1.5e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFX98242.1 - 1.6e-11 44.4 0.0 5.2e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 MATH domain UN_NPL4 PF11543.3 KFX98242.1 - 0.13 12.5 0.0 3.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 RPE65 PF03055.10 KFX98243.1 - 3e-97 326.1 0.1 3.6e-97 325.9 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans_2 PF11951.3 KFX98244.1 - 4.6e-06 25.4 0.5 6.7e-06 24.9 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98244.1 - 0.0057 16.5 2.2 0.0057 16.5 1.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase PF00394.17 KFX98245.1 - 8.7e-32 110.2 0.0 2.3e-31 108.8 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX98245.1 - 9e-23 80.3 9.4 4.1e-22 78.1 0.6 3.0 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFX98245.1 - 1.2e-17 63.7 2.4 2.1e-17 62.9 0.3 2.3 3 0 0 3 3 3 1 Multicopper oxidase Acetyltransf_1 PF00583.19 KFX98246.1 - 5e-07 29.6 0.0 7.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX98246.1 - 4e-06 26.8 0.0 5.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX98246.1 - 2.3e-05 24.2 0.0 0.0003 20.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX98246.1 - 5.3e-05 23.3 0.1 0.00028 20.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX98246.1 - 0.066 13.1 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Pyr_redox_2 PF07992.9 KFX98247.1 - 3.9e-28 98.7 0.2 5.6e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX98247.1 - 8.2e-17 61.3 1.5 1.2e-14 54.4 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX98247.1 - 9.9e-12 45.3 0.1 2.5e-06 27.7 0.0 3.5 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFX98247.1 - 1.5e-05 25.1 0.1 0.0031 17.7 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KFX98247.1 - 3.4e-05 23.7 0.2 0.038 14.0 0.0 3.4 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX98247.1 - 8.6e-05 21.7 0.1 0.00059 19.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFX98247.1 - 0.00037 19.5 1.7 1.5 7.6 0.1 3.5 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFX98247.1 - 0.0046 15.9 0.1 0.18 10.6 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFX98247.1 - 0.011 14.6 3.4 1.2 7.9 0.1 3.3 3 1 1 4 4 4 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KFX98247.1 - 0.025 14.6 0.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KFX98247.1 - 0.04 12.3 0.5 0.64 8.4 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 KFX98247.1 - 0.052 12.5 0.3 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KFX98247.1 - 0.054 12.1 0.1 0.5 8.9 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KFX98247.1 - 0.14 10.9 4.3 0.14 10.9 0.2 2.7 2 1 0 3 3 3 0 FAD binding domain MCPVI PF02993.9 KFX98248.1 - 0.37 10.9 6.2 0.54 10.3 4.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Neisseria_TspB PF05616.8 KFX98248.1 - 2.7 6.2 7.5 3.2 6.0 5.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein WD40 PF00400.27 KFX98249.1 - 2.7e-17 61.9 9.3 5.6e-06 26.0 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat TAF1_subA PF14929.1 KFX98250.1 - 6.5 5.0 6.4 13 4.1 4.4 1.4 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A Kinesin PF00225.18 KFX98251.1 - 8.2e-57 192.3 0.0 1.2e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.11 KFX98251.1 - 0.077 12.7 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain AAA_22 PF13401.1 KFX98251.1 - 0.12 12.5 0.2 0.88 9.7 0.1 2.4 3 1 0 3 3 3 0 AAA domain OPT PF03169.10 KFX98252.1 - 1.7e-129 433.0 49.5 1.9e-129 432.9 34.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KFX98252.1 - 0.27 11.0 4.6 1.1 9.1 3.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DUF4191 PF13829.1 KFX98252.1 - 0.29 10.2 0.9 0.73 8.9 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) COesterase PF00135.23 KFX98253.1 - 4.2e-93 312.8 0.0 2.2e-88 297.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX98253.1 - 1.6e-10 40.9 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX98253.1 - 0.0013 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFX98253.1 - 0.0063 15.7 0.1 0.015 14.5 0.1 1.7 1 0 0 1 1 1 1 Esterase PHB depolymerase Metallophos PF00149.23 KFX98254.1 - 1.2e-19 70.4 1.3 2.5e-19 69.4 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KFX98254.1 - 3.7e-17 62.1 0.9 3.7e-17 62.1 0.6 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KFX98254.1 - 5.8e-07 28.4 0.0 9.5e-07 27.7 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 KFX98254.1 - 0.063 13.4 0.9 0.22 11.6 0.4 2.0 2 0 0 2 2 2 0 Fibronectin type III domain Peroxidase_2 PF01328.12 KFX98255.1 - 7.5e-19 67.5 0.1 1.1e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 HET PF06985.6 KFX98256.1 - 8.8e-27 93.9 0.1 1.6e-26 93.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.28 KFX98257.1 - 0.00012 21.6 0.2 0.00049 19.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFX98257.1 - 0.0022 17.6 0.5 0.0022 17.6 0.3 2.0 2 0 0 2 2 2 1 F-box-like HeLo PF14479.1 KFX98258.1 - 5.4e-10 39.3 0.2 1e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 KFX98258.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98258.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ras PF00071.17 KFX98265.1 - 0.0037 16.6 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MFS_1 PF07690.11 KFX98275.1 - 1.9e-34 118.9 54.7 7.6e-27 93.9 26.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Epiglycanin_C PF14654.1 KFX98275.1 - 0.039 13.9 0.2 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF373 PF04123.8 KFX98275.1 - 0.056 12.4 4.4 1.4 7.8 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF373) GCV_T_C PF08669.6 KFX98276.1 - 2.7e-23 81.8 0.6 4.2e-23 81.1 0.4 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.16 KFX98276.1 - 1.8e-16 60.1 0.1 3.4e-16 59.2 0.0 1.5 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain CybS PF05328.7 KFX98278.1 - 5.8e-49 165.1 0.0 7.9e-49 164.6 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KFX98278.1 - 0.038 13.8 0.9 3.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TPPK_C PF12555.3 KFX98278.1 - 4.2 7.1 6.0 7.1 6.4 0.1 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphokinase C terminal zf-AN1 PF01428.11 KFX98282.1 - 2e-11 43.5 13.9 2.9e-11 43.0 9.6 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger CAF1A PF12253.3 KFX98293.1 - 2.4e-23 82.0 3.5 2.4e-23 82.0 2.4 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KFX98293.1 - 1.3e-13 50.8 45.1 1.3e-13 50.8 31.2 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 KFX98293.1 - 0.0027 16.2 36.3 0.0042 15.6 25.2 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 KFX98293.1 - 0.14 10.7 7.9 0.18 10.3 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 KFX98293.1 - 0.14 10.7 7.6 0.18 10.3 5.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 KFX98293.1 - 5.8 5.0 38.4 9.3 4.3 26.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 KFX98293.1 - 7.2 4.1 15.0 10 3.6 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_transf_17 PF04724.8 KFX98294.1 - 0.00027 20.0 0.1 0.00032 19.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 SLT_2 PF13406.1 KFX98294.1 - 0.052 12.4 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase SLT domain Sds3 PF08598.6 KFX98297.1 - 0.0085 15.6 0.2 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Sds3-like Tmemb_cc2 PF10267.4 KFX98297.1 - 0.04 12.5 0.4 0.051 12.1 0.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Phage_Mu_Gam PF07352.7 KFX98297.1 - 0.11 12.0 1.2 0.19 11.2 0.8 1.4 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Siah-Interact_N PF09032.6 KFX98297.1 - 0.32 11.0 2.6 0.61 10.1 1.8 1.4 1 0 0 1 1 1 0 Siah interacting protein, N terminal Peptidase_S8 PF00082.17 KFX98298.1 - 6.3e-51 173.1 14.3 9.1e-51 172.6 9.9 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFX98298.1 - 2.2e-08 34.5 0.8 4.4e-08 33.5 0.5 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 CBM_2 PF00553.14 KFX98298.1 - 0.02 14.9 0.1 0.065 13.2 0.1 1.9 1 0 0 1 1 1 0 Cellulose binding domain Arginase PF00491.16 KFX98299.1 - 4e-31 108.3 0.0 4.9e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family HNH_2 PF13391.1 KFX98326.1 - 1.7e-08 34.1 0.2 3.6e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 HNH endonuclease Dak1 PF02733.12 KFX98333.1 - 1.2e-112 375.7 5.5 1.8e-112 375.1 3.8 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KFX98333.1 - 5.4e-43 146.6 4.1 9.8e-43 145.8 2.8 1.4 1 0 0 1 1 1 1 DAK2 domain DUF4194 PF13835.1 KFX98333.1 - 0.095 12.1 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) LSM PF01423.17 KFX98334.1 - 2.9e-18 65.1 0.1 3.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain ECH_C PF13766.1 KFX98335.1 - 9.7e-37 125.7 0.0 2.4e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KFX98335.1 - 5.3e-24 84.6 0.0 1e-23 83.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family APC_CDC26 PF10471.4 KFX98352.1 - 2.3 9.0 10.6 0.22 12.2 3.5 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 EAP30 PF04157.11 KFX98353.1 - 9.2e-63 211.3 0.0 1e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.14 KFX98354.1 - 1.5e-39 135.0 0.2 1.7e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HisKA_3 PF07730.8 KFX98355.1 - 0.0095 16.2 0.8 1.2 9.4 0.2 2.2 1 1 1 2 2 2 2 Histidine kinase AATF-Che1 PF13339.1 KFX98355.1 - 0.03 14.4 0.8 0.044 13.9 0.6 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TMP_2 PF06791.8 KFX98355.1 - 0.06 12.9 0.1 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Prophage tail length tape measure protein GAT PF03127.9 KFX98355.1 - 0.095 12.6 0.3 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 GAT domain Sec2p PF06428.6 KFX98355.1 - 0.25 11.1 3.6 0.63 9.9 2.5 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p IncA PF04156.9 KFX98355.1 - 0.31 10.5 4.3 0.39 10.3 3.0 1.1 1 0 0 1 1 1 0 IncA protein AAR2 PF05282.6 KFX98356.1 - 9.7e-59 199.1 0.0 1.3e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 KFX98357.1 - 2.5e-40 137.0 0.5 3e-40 136.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 eIF-3c_N PF05470.7 KFX98358.1 - 4.9e-178 592.9 25.6 1.1e-144 482.8 3.3 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KFX98358.1 - 2.5e-14 53.4 0.8 1e-13 51.4 0.1 2.5 2 0 0 2 2 2 1 PCI domain PDH PF02153.12 KFX98358.1 - 3.3e-12 45.8 0.0 6.8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KFX98358.1 - 3.2e-06 27.1 0.0 1.3e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX98358.1 - 4.8e-05 23.7 1.8 0.00015 22.1 0.0 2.8 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFX98358.1 - 0.0006 19.5 0.6 0.0032 17.1 0.0 2.5 2 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX98358.1 - 0.0038 16.3 0.0 0.009 15.1 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KFX98358.1 - 0.0044 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 KFX98358.1 - 0.02 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 KFX98358.1 - 0.08 12.9 0.0 0.58 10.1 0.0 2.6 1 0 0 1 1 1 0 TrkA-N domain RICTOR_N PF14664.1 KFX98359.1 - 6.9e-140 465.8 5.3 3.3e-139 463.6 1.4 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KFX98359.1 - 9.5e-87 289.7 0.8 1.1e-85 286.2 0.1 2.8 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KFX98359.1 - 2.5e-42 143.4 0.0 1e-40 138.2 0.0 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KFX98359.1 - 1.2e-29 102.0 2.0 8.5e-28 96.1 0.0 4.3 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KFX98359.1 - 4e-12 45.6 9.7 1.4e-11 43.9 6.7 2.0 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 KFX98359.1 - 0.00012 22.2 2.5 3.7 7.8 0.0 5.5 5 0 0 5 5 5 1 HEAT repeats IncA PF04156.9 KFX98359.1 - 0.032 13.8 4.2 0.065 12.8 2.9 1.4 1 0 0 1 1 1 0 IncA protein DUF2443 PF10398.4 KFX98359.1 - 0.053 13.3 0.7 0.17 11.7 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Noelin-1 PF12308.3 KFX98359.1 - 0.061 13.1 1.2 0.16 11.8 0.8 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein HOOK PF05622.7 KFX98359.1 - 0.11 10.2 7.9 0.2 9.4 4.3 1.9 2 0 0 2 2 2 0 HOOK protein Uricase PF01014.13 KFX98360.1 - 5e-85 282.5 1.8 1.8e-45 154.3 0.7 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KFX98360.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 KFX98361.1 - 1.1e-39 135.4 0.0 1.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Bromodomain PF00439.20 KFX98361.1 - 0.063 13.1 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Bromodomain NinG PF05766.7 KFX98361.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.4 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein TPR_1 PF00515.23 KFX98362.1 - 2.8e-12 45.6 3.5 3.6e-05 23.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX98362.1 - 3.4e-12 45.8 0.6 4.8e-08 32.5 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KFX98362.1 - 1.6e-10 40.0 2.9 0.00069 19.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 KFX98362.1 - 1.2e-06 28.0 0.5 2.4e-06 27.1 0.4 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 KFX98362.1 - 7.8e-06 25.7 0.0 0.0016 18.3 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98362.1 - 4.1e-05 23.0 1.2 0.074 12.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX98362.1 - 7e-05 22.3 0.0 0.00066 19.2 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Dam PF05869.6 KFX98362.1 - 0.0033 16.8 3.7 14 5.0 0.1 4.3 4 0 0 4 4 4 0 DNA N-6-adenine-methyltransferase (Dam) TPR_6 PF13174.1 KFX98362.1 - 0.0043 17.4 0.1 41 4.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98362.1 - 0.02 15.5 0.8 0.13 13.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98362.1 - 0.031 14.4 0.1 0.26 11.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fibrillarin PF01269.12 KFX98363.1 - 3e-107 356.7 0.0 3.6e-107 356.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KFX98363.1 - 1.4e-05 24.7 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KFX98363.1 - 0.01 15.3 0.1 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KFX98363.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L11_N PF03946.9 KFX98364.1 - 7.8e-18 63.6 0.0 1.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KFX98364.1 - 1.8e-11 43.9 0.3 3e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 KFX98364.1 - 0.0046 16.5 0.2 0.19 11.4 0.0 2.6 1 1 1 2 2 2 2 Translation initiation factor IF-2, N-terminal region Glyco_transf_41 PF13844.1 KFX98365.1 - 1.8e-95 319.6 0.0 8.8e-52 175.6 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KFX98365.1 - 8.7e-23 79.7 11.1 3.8e-09 36.0 0.1 4.7 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KFX98365.1 - 1.2e-17 62.6 8.4 0.0001 21.7 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98365.1 - 5.2e-15 54.0 11.8 0.0053 16.5 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFX98365.1 - 4.7e-13 48.8 12.7 9e-07 28.7 0.9 4.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98365.1 - 4.6e-11 42.0 6.0 0.094 12.9 0.3 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX98365.1 - 6.3e-11 41.2 3.5 0.0012 18.4 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98365.1 - 8.4e-11 41.5 4.3 0.014 15.9 0.0 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98365.1 - 9e-11 40.7 3.7 0.01 15.5 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98365.1 - 4.9e-10 39.8 8.1 0.0014 19.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFX98365.1 - 3.7e-09 36.2 8.9 0.034 14.0 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFX98365.1 - 8.4e-09 35.6 3.2 0.0023 18.2 0.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX98365.1 - 0.00021 21.3 1.1 0.17 11.9 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFX98365.1 - 0.0018 17.3 0.1 0.058 12.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.2 KFX98365.1 - 0.011 15.7 1.7 0.037 14.0 0.2 2.5 3 0 0 3 3 3 0 Tetratrico peptide repeat BTAD PF03704.12 KFX98365.1 - 0.037 14.3 1.0 3.6 7.8 0.0 2.9 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 KFX98365.1 - 0.043 14.2 4.9 16 6.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFX98365.1 - 0.13 12.0 4.7 0.59 10.0 0.2 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat YagB_YeeU_YfjZ PF06154.6 KFX98381.1 - 0.0064 16.7 0.1 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 YagB/YeeU/YfjZ family MFS_1 PF07690.11 KFX98382.1 - 3.7e-44 150.8 56.7 1.1e-43 149.3 38.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98382.1 - 7.8e-13 47.7 11.1 7.8e-13 47.7 7.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Sod_Cu PF00080.15 KFX98383.1 - 5.9e-15 55.6 0.0 9.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KFX98383.1 - 1.8e-12 47.1 0.0 4.5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Apc4_WD40 PF12894.2 KFX98384.1 - 0.0067 15.9 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.1 KFX98384.1 - 0.3 10.9 7.7 0.035 13.9 1.9 2.0 2 0 0 2 2 2 0 Ring finger domain DUF2361 PF10153.4 KFX98385.1 - 2.5e-39 133.9 8.6 2.5e-39 133.9 6.0 2.4 2 1 1 3 3 3 1 Uncharacterised conserved protein (DUF2361) Asp-B-Hydro_N PF05279.6 KFX98385.1 - 2 8.2 10.7 1.6 8.5 6.3 1.6 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region dsrm PF00035.20 KFX98386.1 - 2.9e-06 27.7 0.0 1.1e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif NRDE PF05742.7 KFX98387.1 - 9.7e-48 162.8 0.0 1.8e-47 161.9 0.0 1.4 1 1 0 1 1 1 1 NRDE protein MUG2_C PF08593.5 KFX98388.1 - 0.069 13.3 2.1 0.13 12.5 0.4 2.3 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal Tfb2 PF03849.9 KFX98389.1 - 2.4e-134 447.6 0.0 3.8e-134 446.9 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KFX98389.1 - 5.6e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.17 KFX98390.1 - 8.3e-14 51.4 0.2 1.3e-13 50.8 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KFX98390.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Homeobox PF00046.24 KFX98392.1 - 4.6e-17 61.3 3.2 9.2e-17 60.4 2.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFX98392.1 - 0.026 14.2 0.1 0.11 12.2 0.1 2.1 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_ner PF04546.8 KFX98392.1 - 0.11 12.1 5.0 0.21 11.1 3.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region 3HCDH_N PF02737.13 KFX98393.1 - 1.3e-51 174.7 0.3 1.7e-51 174.4 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFX98393.1 - 3.9e-34 116.9 0.0 8e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFX98393.1 - 0.00091 19.1 0.1 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 KFX98393.1 - 0.0054 15.6 0.7 0.0093 14.9 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 KFX98393.1 - 0.0092 15.7 0.2 0.017 14.8 0.2 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KFX98393.1 - 0.018 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KFX98393.1 - 0.088 13.2 0.4 0.25 11.7 0.3 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KFX98393.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase TIMELESS PF04821.9 KFX98394.1 - 2.2e-90 302.5 0.0 2.2e-90 302.5 0.0 1.7 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KFX98394.1 - 2.5e-30 105.9 10.0 2.5e-30 105.9 6.9 3.2 2 1 0 2 2 2 1 Timeless protein C terminal region Cut8_N PF14482.1 KFX98394.1 - 4.3 7.4 11.7 5.4 7.0 1.6 3.9 3 0 0 3 3 3 0 Cut8 proteasome-binding domain KAP PF05804.7 KFX98395.1 - 0.00011 20.2 0.0 0.015 13.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KFX98395.1 - 0.017 14.2 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 V-ATPase subunit H CDRN PF05174.7 KFX98395.1 - 0.46 9.9 4.1 19 4.8 0.0 3.8 4 0 0 4 4 4 0 Cysteine-rich D. radiodurans N terminus DPM3 PF08285.6 KFX98396.1 - 3.6e-33 113.2 0.1 4.8e-33 112.8 0.1 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Spc7_N PF15402.1 KFX98396.1 - 4.1 5.2 7.5 4.9 5.0 5.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CENP-P PF13096.1 KFX98397.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.0 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Helicase_C PF00271.26 KFX98401.1 - 5.3e-12 45.4 0.0 1.3e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Oxysterol_BP PF01237.13 KFX98404.1 - 1.2e-09 37.1 0.0 1.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein K_channel_TID PF07941.6 KFX98414.1 - 2.9 8.1 7.0 0.33 11.1 1.4 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1748 PF08520.5 KFX98430.1 - 1.6e-33 114.1 0.2 1.9e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) SE PF08491.5 KFX98436.1 - 7.8e-21 74.1 0.0 1.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.2 KFX98436.1 - 7.5e-09 35.1 0.0 1.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFX98436.1 - 2.4e-08 33.2 0.0 7.1e-07 28.4 0.1 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFX98436.1 - 3.4e-07 29.6 0.0 5.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KFX98436.1 - 2.7e-06 26.5 0.1 0.00062 18.7 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFX98436.1 - 1.1e-05 24.5 0.8 2.7e-05 23.1 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain PPR_3 PF13812.1 KFX98436.1 - 0.0002 21.3 0.1 3.2 8.2 0.0 5.9 6 0 0 6 6 5 1 Pentatricopeptide repeat domain NAD_binding_8 PF13450.1 KFX98436.1 - 0.00038 20.4 0.2 0.0018 18.2 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX98436.1 - 0.00039 20.3 0.1 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX98436.1 - 0.00041 19.5 0.0 0.001 18.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family PPR_2 PF13041.1 KFX98436.1 - 0.00097 19.0 0.1 0.0049 16.8 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family 3HCDH_N PF02737.13 KFX98436.1 - 0.0052 16.4 0.1 0.014 15.0 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFX98436.1 - 0.0072 14.8 0.2 0.012 14.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KFX98436.1 - 0.0073 16.6 0.4 0.033 14.5 0.1 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX98436.1 - 0.016 13.8 0.1 0.78 8.3 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 KFX98436.1 - 0.2 11.4 0.3 0.5 10.1 0.2 1.7 1 0 0 1 1 1 0 ThiF family Fic PF02661.13 KFX98437.1 - 9.1e-16 58.3 0.0 2.1e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Ribonuc_L-PSP PF01042.16 KFX98438.1 - 1.2e-25 89.6 0.0 1.4e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.7 KFX98438.1 - 0.02 14.6 0.1 0.047 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) Mito_carr PF00153.22 KFX98439.1 - 1.9e-64 213.4 4.2 6.8e-22 76.9 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein EIF_2_alpha PF07541.7 KFX98440.1 - 3.3e-38 129.9 0.0 6.7e-38 128.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KFX98440.1 - 1.6e-12 47.3 1.0 3.3e-12 46.3 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S24 PF00717.18 KFX98440.1 - 0.00058 19.4 1.2 0.004 16.7 0.0 3.0 2 2 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFX98440.1 - 0.0015 18.0 0.1 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Bacteriocin_IIi PF11758.3 KFX98440.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin cNMP_binding PF00027.24 KFX98441.1 - 6.2e-40 134.9 0.1 6.1e-20 70.8 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KFX98441.1 - 5.8e-18 65.5 7.2 4.2e-17 62.7 3.6 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase DUF3568 PF12092.3 KFX98441.1 - 0.23 11.1 0.6 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Sugar_tr PF00083.19 KFX98443.1 - 7.6e-72 242.3 18.3 9.1e-71 238.7 12.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98443.1 - 4.4e-16 58.5 27.0 1.1e-14 53.8 15.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily UPF0233 PF06781.7 KFX98443.1 - 0.31 10.6 0.0 0.31 10.6 0.0 3.3 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0233) MFS_1 PF07690.11 KFX98446.1 - 1.1e-23 83.5 39.7 1.7e-22 79.6 27.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Lon_C PF05362.8 KFX98446.1 - 0.057 12.7 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain Phage_holin_3 PF05106.7 KFX98447.1 - 0.025 14.5 1.3 0.08 12.9 0.9 1.8 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) CPSF_A PF03178.10 KFX98448.1 - 7e-84 281.6 0.0 2.1e-83 280.0 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KFX98448.1 - 4.7e-05 21.7 0.0 0.00057 18.1 0.0 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PBP1_TM PF14812.1 KFX98448.1 - 8.7 6.7 8.6 0.59 10.4 1.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LMBR1 PF04791.11 KFX98449.1 - 5e-16 58.3 14.0 4.3e-15 55.2 5.9 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein Fungal_trans PF04082.13 KFX98450.1 - 2e-16 59.6 0.2 3.1e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98450.1 - 1.5e-05 24.7 12.5 2.6e-05 24.0 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_6 PF01341.12 KFX98451.1 - 6.4e-93 311.4 1.3 7.7e-93 311.1 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_114 PF03537.8 KFX98452.1 - 2.6e-25 87.9 0.4 6.3e-25 86.7 0.3 1.7 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Abhydrolase_6 PF12697.2 KFX98452.1 - 1.8e-23 83.6 0.1 2.9e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX98452.1 - 8.6e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KFX98452.1 - 1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX98452.1 - 0.00019 21.0 0.1 0.23 10.9 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KFX98452.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF2726 PF10881.3 KFX98452.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) ApbA_C PF08546.6 KFX98453.1 - 7e-25 87.4 0.0 1.4e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFX98453.1 - 6.9e-24 84.0 0.0 1.3e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.13 KFX98453.1 - 0.0025 17.6 12.1 0.0042 16.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S21e PF01249.13 KFX98454.1 - 1.2e-36 124.4 0.1 1.4e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.5 KFX98455.1 - 4.5e-21 74.3 0.0 1.1e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Clathrin_H_link PF13838.1 KFX98455.1 - 0.15 12.0 0.6 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Clathrin-H-link Aldo_ket_red PF00248.16 KFX98456.1 - 1.2e-48 165.3 0.0 1.5e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bax1-I PF01027.15 KFX98457.1 - 6.5e-32 110.8 13.8 6.5e-32 110.8 9.6 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF4557 PF15101.1 KFX98459.1 - 0.13 12.0 0.9 0.17 11.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SnoaL_4 PF13577.1 KFX98460.1 - 2.9e-22 78.9 0.0 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KFX98460.1 - 0.0012 19.3 0.1 0.0028 18.1 0.1 1.6 1 1 0 1 1 1 1 Putative lumazine-binding SnoaL_3 PF13474.1 KFX98460.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFX98460.1 - 0.035 14.2 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Scytalone_dh PF02982.9 KFX98460.1 - 0.045 13.3 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Scytalone dehydratase SnoaL_2 PF12680.2 KFX98460.1 - 0.064 13.6 0.1 0.097 13.0 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain NOGCT PF08155.6 KFX98462.1 - 1.5e-29 101.4 2.8 5.9e-29 99.5 1.9 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 KFX98462.1 - 6.7e-27 93.1 0.7 1.6e-26 91.9 0.5 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KFX98462.1 - 1.2e-14 54.2 0.0 2.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX98462.1 - 4.1e-08 32.6 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFX98462.1 - 0.00024 21.5 0.0 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KFX98462.1 - 0.027 14.4 0.2 1.5 8.7 0.1 3.2 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KFX98462.1 - 0.03 14.1 0.0 8.7 6.1 0.0 2.6 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.1 KFX98462.1 - 0.11 12.6 0.1 3 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Asp_protease PF09668.5 KFX98463.1 - 8.8e-63 209.4 0.2 1.3e-62 208.8 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KFX98463.1 - 5.5e-12 46.0 0.0 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 KFX98463.1 - 3.4e-08 33.0 0.0 7.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 KFX98463.1 - 2.2e-07 30.8 0.0 3.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFX98463.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KFX98463.1 - 0.00019 21.3 0.0 0.00069 19.4 0.0 2.0 2 1 0 2 2 2 1 Retroviral aspartyl protease RuvA_C PF07499.8 KFX98463.1 - 0.026 14.6 0.0 0.078 13.1 0.0 1.8 1 0 0 1 1 1 0 RuvA, C-terminal domain UBA_4 PF14555.1 KFX98463.1 - 0.043 13.3 1.3 0.079 12.4 0.2 2.0 2 0 0 2 2 2 0 UBA-like domain Methyltransf_8 PF05148.10 KFX98464.1 - 4.6e-55 186.6 0.0 4.7e-53 180.0 0.0 2.9 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KFX98464.1 - 1.4e-07 31.9 0.1 6.3e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX98464.1 - 0.0034 16.9 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.1 KFX98464.1 - 0.0039 16.8 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Macoilin PF09726.4 KFX98464.1 - 2.4 6.3 19.4 3.8 5.6 13.4 1.2 1 0 0 1 1 1 0 Transmembrane protein TATR PF03430.8 KFX98464.1 - 7.5 5.0 16.0 14 4.1 11.1 1.4 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Fungal_trans_2 PF11951.3 KFX98465.1 - 1.1e-19 70.2 0.7 1.2e-12 47.1 0.6 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98465.1 - 1.4e-07 31.2 10.7 2.4e-07 30.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 KFX98466.1 - 8.9e-57 191.4 0.0 1.1e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX98466.1 - 1.2e-13 50.1 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KFX98466.1 - 0.0043 16.7 0.2 0.13 11.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 KFX98467.1 - 3.3e-131 438.2 0.2 3.3e-131 438.2 0.2 1.7 2 0 0 2 2 2 1 Spc97 / Spc98 family Sel1 PF08238.7 KFX98469.1 - 4.6e-20 71.5 8.8 1.9e-06 28.3 0.2 3.4 3 0 0 3 3 3 3 Sel1 repeat TraC PF07820.7 KFX98469.1 - 0.024 14.8 0.3 0.043 14.0 0.2 1.4 1 0 0 1 1 1 0 TraC-like protein TPR_14 PF13428.1 KFX98469.1 - 0.23 12.2 3.7 18 6.3 1.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.17 KFX98471.1 - 2.9e-09 36.2 0.4 0.2 11.8 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat CLASP_N PF12348.3 KFX98471.1 - 7.1e-05 22.2 0.0 0.0066 15.8 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 KFX98471.1 - 0.0014 19.0 6.3 8.2 7.0 0.2 5.3 5 1 1 6 6 6 2 HEAT-like repeat HsbA PF12296.3 KFX98471.1 - 0.019 14.8 0.5 0.97 9.2 0.1 2.7 2 1 1 3 3 3 0 Hydrophobic surface binding protein A TAN PF11640.3 KFX98471.1 - 0.06 13.0 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF3306 PF11748.3 KFX98471.1 - 0.16 12.6 5.7 0.078 13.6 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) GCFC PF07842.7 KFX98472.1 - 4e-78 262.5 3.8 4e-78 262.5 2.6 1.6 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KFX98472.1 - 2.7e-15 55.8 4.5 9.6e-15 54.1 3.1 2.0 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 KFX98472.1 - 5.5e-13 48.9 9.2 5.5e-13 48.9 6.3 2.7 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KFX98472.1 - 1.1e-07 31.5 2.5 1.1e-07 31.5 1.8 2.6 3 1 0 3 3 3 1 DExH-box splicing factor binding site PH_10 PF15411.1 KFX98473.1 - 1.3e-41 141.3 0.3 2.4e-41 140.5 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KFX98473.1 - 2.9e-31 108.7 0.0 5.6e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 KFX98473.1 - 7.4e-31 106.0 0.1 1.4e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 KFX98473.1 - 3.7e-08 32.9 0.0 1.1e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 KFX98474.1 - 5.2e-42 140.2 1.5 3.1e-08 33.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KFX98474.1 - 2.2e-05 24.0 0.2 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX98474.1 - 0.00021 20.8 0.1 0.00053 19.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFX98474.1 - 0.00045 18.4 0.2 0.049 11.7 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 DUF605 PF04652.11 KFX98474.1 - 0.0038 16.6 10.8 0.0038 16.6 7.5 2.1 2 0 0 2 2 2 1 Vta1 like RRF PF01765.14 KFX98480.1 - 8.4e-11 41.6 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Mitofilin PF09731.4 KFX98482.1 - 3.4e-70 237.3 1.1 3.7e-70 237.2 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Mur_ligase_C PF02875.16 KFX98483.1 - 0.00066 19.6 0.0 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 KFX98483.1 - 0.003 17.6 0.5 0.12 12.3 0.4 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_M PF08245.7 KFX98484.1 - 1.1e-05 25.5 0.4 0.00011 22.2 0.3 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Fungal_trans_2 PF11951.3 KFX98487.1 - 1.5e-09 36.9 5.0 2.2e-09 36.4 3.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98487.1 - 7.1e-09 35.4 6.9 1.2e-08 34.7 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain INO80_Ies4 PF08193.6 KFX98487.1 - 0.046 13.6 1.6 0.071 13.0 1.1 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 RTA1 PF04479.8 KFX98488.1 - 1e-39 136.3 2.9 1e-39 136.3 2.0 1.4 1 1 1 2 2 2 1 RTA1 like protein FTA4 PF13093.1 KFX98489.1 - 1.5e-50 171.5 0.1 1.8e-50 171.3 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 COG2 PF06148.6 KFX98489.1 - 0.028 14.3 1.0 0.044 13.6 0.2 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CR6_interact PF10147.4 KFX98489.1 - 0.044 13.0 1.7 0.076 12.3 1.2 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GAS PF13851.1 KFX98489.1 - 0.057 12.6 1.3 0.1 11.8 0.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Acyl-CoA_dh_1 PF00441.19 KFX98490.1 - 2.3e-30 105.7 2.6 3.6e-30 105.0 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KFX98490.1 - 9.8e-22 76.5 0.2 3e-21 75.0 0.2 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KFX98490.1 - 3.7e-17 61.5 0.6 8.2e-17 60.4 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX98490.1 - 1.3e-09 38.6 0.3 1.3e-08 35.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFX98490.1 - 4.1e-07 30.3 0.3 9.1e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF572 PF04502.8 KFX98492.1 - 2.7e-72 243.7 7.8 3.2e-72 243.4 5.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 KFX98492.1 - 0.091 12.6 0.6 0.42 10.4 0.4 1.9 1 1 0 1 1 1 0 Benyvirus 14KDa protein zf-dskA_traR PF01258.12 KFX98492.1 - 0.25 11.1 0.2 0.25 11.1 0.1 2.3 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-FCS PF06467.9 KFX98492.1 - 0.59 9.8 2.3 5.4 6.7 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif CrtC PF07143.6 KFX98520.1 - 3e-18 66.1 0.0 6.9e-18 64.9 0.0 1.5 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) AMP-binding PF00501.23 KFX98521.1 - 2.1e-73 247.1 0.0 2.7e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX98521.1 - 7.7e-14 52.4 0.1 1.5e-13 51.4 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2236 PF09995.4 KFX98522.1 - 1.7e-35 122.4 0.4 2.5e-35 121.9 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3712 PF12505.3 KFX98522.1 - 3.8e-29 101.2 0.8 7.3e-29 100.3 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) ESSS PF10183.4 KFX98522.1 - 0.059 13.7 0.1 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF805 PF05656.9 KFX98522.1 - 0.061 13.1 0.2 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Peptidase_M50 PF02163.17 KFX98523.1 - 0.034 13.1 0.4 0.043 12.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase family M50 DUF2880 PF11082.3 KFX98523.1 - 0.058 13.2 0.1 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2880) Serine_rich PF08824.5 KFX98523.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF3425 PF11905.3 KFX98524.1 - 3.6e-20 72.2 2.3 8.4e-20 71.0 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX98524.1 - 0.0001 22.1 13.0 0.00083 19.2 7.8 2.4 1 1 1 2 2 2 2 bZIP transcription factor SPO22 PF08631.5 KFX98524.1 - 0.059 12.4 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF1444 PF07285.6 KFX98524.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) bZIP_2 PF07716.10 KFX98524.1 - 0.2 11.5 12.0 5.1 7.0 5.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF837 PF05769.6 KFX98524.1 - 0.3 10.5 4.8 0.53 9.8 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) ADH_zinc_N PF00107.21 KFX98525.1 - 3.5e-25 88.0 0.0 5.8e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.11 KFX98525.1 - 0.079 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AMP-binding PF00501.23 KFX98526.1 - 7.2e-82 275.0 0.0 1.1e-81 274.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFX98526.1 - 1.6e-60 204.1 0.0 7.7e-60 201.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KFX98526.1 - 1.1e-36 126.2 4.5 7.2e-34 117.1 1.4 2.8 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KFX98526.1 - 2.3e-20 73.0 3.2 9.5e-18 64.5 1.0 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KFX98526.1 - 5.9e-19 68.7 0.1 1.2e-18 67.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX98526.1 - 3.4e-18 65.9 0.3 2.4e-10 40.2 0.0 3.9 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX98526.1 - 1e-11 44.0 0.1 2e-07 29.9 0.0 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 KFX98526.1 - 2.7e-11 43.5 0.0 7.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX98526.1 - 1.4e-06 29.1 0.2 1e-05 26.4 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 KFX98526.1 - 1.9e-06 27.0 0.9 0.00042 19.3 0.0 3.0 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFX98526.1 - 3.2e-06 27.2 4.0 0.0051 16.8 0.8 4.2 4 1 0 4 4 4 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX98526.1 - 5.2e-05 22.2 2.4 0.0084 15.0 0.2 3.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KFX98526.1 - 0.0011 18.6 0.5 0.003 17.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFX98526.1 - 0.009 15.0 0.2 0.022 13.8 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 KFX98526.1 - 0.036 13.6 0.4 0.087 12.4 0.3 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 KFX98526.1 - 0.054 12.7 2.0 1.2 8.3 1.2 3.0 3 0 0 3 3 3 0 NmrA-like family 3HCDH_N PF02737.13 KFX98526.1 - 0.43 10.2 3.8 0.34 10.5 0.5 2.4 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.15 KFX98527.1 - 3.6e-27 95.3 0.0 8e-22 77.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX98527.1 - 6e-19 68.8 0.0 1e-18 68.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX98527.1 - 4.1e-10 39.5 0.0 2.2e-09 37.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX98527.1 - 0.0012 18.3 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.7 KFX98527.1 - 0.0027 16.3 0.0 0.0042 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ndr PF03096.9 KFX98527.1 - 0.011 14.1 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family LIP PF03583.9 KFX98527.1 - 0.046 12.9 0.0 0.094 11.9 0.0 1.4 1 1 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.16 KFX98527.1 - 0.078 12.1 0.0 0.99 8.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFX98527.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase MFS_1 PF07690.11 KFX98528.1 - 6.1e-36 123.8 34.5 1.3e-35 122.8 23.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 KFX98528.1 - 4 6.9 0.0 4 6.9 0.0 5.4 6 1 1 7 7 7 0 Protein of unknown function (DUF1049) VKOR PF07884.9 KFX98529.1 - 1 9.1 18.7 0.11 12.4 0.8 3.1 1 1 2 3 3 3 0 Vitamin K epoxide reductase family NAD_binding_8 PF13450.1 KFX98530.1 - 0.00045 20.2 0.2 0.00088 19.2 0.2 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX98530.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KFX98530.1 - 0.043 13.8 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 KFX98530.1 - 0.05 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX98530.1 - 0.075 12.0 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 KFX98530.1 - 0.11 11.4 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX98530.1 - 0.13 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4231 PF14015.1 KFX98540.1 - 0.013 15.4 0.9 0.013 15.4 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) p450 PF00067.17 KFX98541.1 - 1.5e-51 175.3 0.0 2.1e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.17 KFX98542.1 - 7.1e-12 44.9 0.8 1.1e-11 44.3 0.5 1.3 1 0 0 1 1 1 1 Cupin tify PF06200.9 KFX98542.1 - 0.0049 16.1 0.2 0.012 14.8 0.1 1.6 1 0 0 1 1 1 1 tify domain MFS_1 PF07690.11 KFX98546.1 - 1.1e-38 132.8 27.0 1.1e-38 132.8 18.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Tweety PF04906.8 KFX98546.1 - 0.1 10.9 1.5 0.19 10.0 1.0 1.3 1 0 0 1 1 1 0 Tweety Fungal_trans PF04082.13 KFX98547.1 - 3.2e-08 32.7 0.8 6.5e-08 31.7 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98547.1 - 6.6e-07 29.1 10.4 9.9e-07 28.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_11 PF14833.1 KFX98548.1 - 2.2e-69 231.1 2.8 4.2e-34 117.2 0.0 2.6 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KFX98548.1 - 1.1e-68 230.2 7.4 8.4e-36 123.2 3.2 2.7 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1537 PF07005.6 KFX98548.1 - 1.7e-22 80.1 6.9 8.4e-22 77.9 1.8 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 F420_oxidored PF03807.12 KFX98548.1 - 1.4e-12 47.8 2.4 6.4e-06 26.5 0.9 3.2 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Cellulase PF00150.13 KFX98548.1 - 4.9e-10 39.0 0.0 4.9e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) 3HCDH_N PF02737.13 KFX98548.1 - 7.6e-09 35.4 3.3 0.0014 18.2 0.9 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFX98548.1 - 1.4e-05 24.5 6.3 2.3 7.5 1.5 4.4 2 2 1 3 3 3 3 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX98548.1 - 5e-05 22.5 0.1 0.0061 15.7 0.0 2.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KFX98548.1 - 0.0026 17.2 1.4 0.38 10.1 0.0 2.6 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF4246 PF14033.1 KFX98549.1 - 1.1e-150 502.6 0.0 1.3e-150 502.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Pectate_lyase_3 PF12708.2 KFX98550.1 - 5.3e-67 226.2 13.6 2.4e-51 175.0 4.6 2.7 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KFX98550.1 - 1.2e-05 24.7 0.4 0.15 11.5 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ank_2 PF12796.2 KFX98553.1 - 6.5e-28 96.9 0.1 3.1e-12 46.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX98553.1 - 5.1e-21 74.2 0.0 7.9e-10 38.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 KFX98553.1 - 4.3e-17 62.2 0.5 5.5e-07 29.4 0.0 3.6 3 0 0 3 3 3 3 NACHT domain Ank PF00023.25 KFX98553.1 - 1e-16 59.7 2.1 1.1e-06 28.1 0.0 6.1 6 0 0 6 6 5 3 Ankyrin repeat Ank_4 PF13637.1 KFX98553.1 - 1.3e-15 57.3 0.0 2e-05 24.9 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX98553.1 - 1.9e-12 46.1 3.3 0.0019 18.2 0.0 5.9 7 0 0 7 7 4 3 Ankyrin repeat AAA_22 PF13401.1 KFX98553.1 - 5.3e-11 42.7 0.2 0.0004 20.5 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KFX98553.1 - 8.3e-08 32.4 2.9 0.017 15.1 0.0 4.3 3 2 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 KFX98553.1 - 3.8e-07 30.2 0.0 0.0073 16.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Abhydrolase_6 PF12697.2 KFX98553.1 - 3.3e-05 23.8 0.0 6.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX98553.1 - 3.7e-05 23.5 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX98553.1 - 0.00015 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ABC_tran PF00005.22 KFX98553.1 - 0.00054 20.2 0.0 0.089 13.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.1 KFX98553.1 - 0.00066 19.5 0.0 0.0044 16.8 0.0 2.3 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KFX98553.1 - 0.00096 18.0 0.0 0.38 9.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KFX98553.1 - 0.0011 19.2 0.0 0.48 10.6 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KFX98553.1 - 0.002 17.8 0.0 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_19 PF13245.1 KFX98553.1 - 0.0052 16.5 0.0 0.33 10.7 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain DUF2075 PF09848.4 KFX98553.1 - 0.0054 15.7 0.0 0.4 9.6 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KFX98553.1 - 0.0089 16.8 0.0 0.058 14.2 0.0 2.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KFX98553.1 - 0.011 15.3 0.0 0.5 10.0 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFX98553.1 - 0.011 16.0 0.0 0.059 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.8 KFX98553.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein Sigma54_activ_2 PF14532.1 KFX98553.1 - 0.021 14.8 0.0 0.077 13.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 KFX98553.1 - 0.022 13.7 1.4 0.025 13.5 0.0 1.7 2 0 0 2 2 1 0 KAP family P-loop domain NTPase_1 PF03266.10 KFX98553.1 - 0.047 13.4 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 KFX98553.1 - 0.092 11.8 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 KFX98553.1 - 0.13 11.4 0.0 0.36 10.0 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.7 KFX98553.1 - 0.13 11.2 0.0 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus FAD_binding_3 PF01494.14 KFX98554.1 - 1.2e-24 87.0 0.0 3.8e-24 85.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX98554.1 - 8.3e-14 51.2 3.3 9.6e-07 28.0 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX98554.1 - 2.2e-08 34.2 0.0 5.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX98554.1 - 1.3e-07 31.9 0.4 0.014 15.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX98554.1 - 1.4e-07 30.7 0.7 1.6e-06 27.2 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFX98554.1 - 1.5e-06 27.6 0.2 2.7e-06 26.7 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX98554.1 - 9.9e-06 24.2 1.0 7.4e-05 21.3 0.7 2.1 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KFX98554.1 - 0.00013 21.9 0.2 0.0003 20.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KFX98554.1 - 0.00075 18.2 1.6 0.0098 14.5 0.1 2.4 2 1 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.17 KFX98554.1 - 0.0014 17.5 0.5 0.0021 16.9 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KFX98554.1 - 0.005 15.9 0.1 0.0085 15.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KFX98554.1 - 0.017 13.9 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.1 KFX98554.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX98554.1 - 0.079 11.8 0.1 0.42 9.4 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KFX98554.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyoxalase PF00903.20 KFX98555.1 - 1.8e-14 53.8 0.1 2.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX98555.1 - 5.1e-09 36.6 0.1 1e-08 35.7 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFX98555.1 - 6.2e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TOM_sub5 PF15178.1 KFX98555.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog TAP42 PF04177.7 KFX98556.1 - 1.2e-96 323.6 0.0 1.3e-96 323.5 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family HAT PF02184.11 KFX98556.1 - 0.15 11.8 0.4 0.31 10.8 0.3 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Ribonuclease_3 PF00636.21 KFX98557.1 - 3.9e-40 136.8 0.0 9.4e-19 67.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 KFX98557.1 - 8.8e-23 79.8 0.1 6.9e-21 73.8 0.0 3.1 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 KFX98557.1 - 2.6e-22 79.1 0.0 7.6e-10 38.8 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 KFX98557.1 - 2.1e-15 56.3 0.1 5.6e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX98557.1 - 1.5e-11 44.4 0.0 4.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX98557.1 - 5.9e-11 42.1 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 KFX98557.1 - 0.0021 18.6 0.0 1.5 9.4 0.0 3.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif SNF2_N PF00176.18 KFX98557.1 - 0.038 12.7 0.5 0.13 10.9 0.1 2.0 2 1 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.4 KFX98557.1 - 0.072 12.0 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CPSase_L_D2 PF02786.12 KFX98558.1 - 1.2e-112 374.3 0.2 1.9e-84 282.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KFX98558.1 - 3.6e-44 150.5 0.0 7.9e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KFX98558.1 - 5e-44 148.9 0.0 1.1e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 KFX98558.1 - 2.4e-42 143.6 0.1 6.2e-42 142.2 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 KFX98558.1 - 1.1e-41 141.7 0.0 2.3e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATP-grasp_4 PF13535.1 KFX98558.1 - 3e-34 118.3 0.4 3.3e-20 72.6 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 KFX98558.1 - 1.2e-33 116.1 0.0 3.1e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_chain PF00289.17 KFX98558.1 - 5.3e-33 113.4 0.0 1.3e-16 60.6 0.0 3.1 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain MGS PF02142.17 KFX98558.1 - 8.7e-22 76.8 0.0 1e-20 73.4 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 KFX98558.1 - 2.7e-19 69.1 0.1 2.5e-09 36.3 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX98558.1 - 5.4e-15 55.3 0.4 9.7e-07 28.3 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFX98558.1 - 9.1e-15 54.4 0.1 1.8e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KFX98558.1 - 2.4e-06 27.1 0.5 7.9e-05 22.1 0.4 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KFX98558.1 - 1.8e-05 24.6 0.4 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KFX98558.1 - 0.0019 17.7 0.3 1.7 8.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 KFX98558.1 - 0.0055 16.1 0.0 0.016 14.6 0.0 1.8 1 0 0 1 1 1 1 DJ-1/PfpI family Kdo PF06293.9 KFX98559.1 - 0.013 14.6 0.0 0.17 10.9 0.0 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFX98559.1 - 0.033 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Hamartin PF04388.7 KFX98562.1 - 5.9e-45 154.1 10.7 5.9e-45 154.1 7.4 2.3 1 1 1 2 2 2 1 Hamartin protein Pex2_Pex12 PF04757.9 KFX98563.1 - 1.4e-55 188.1 3.5 1.8e-55 187.8 2.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KFX98563.1 - 8.9e-06 25.6 2.6 1.6e-05 24.8 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX98563.1 - 6.3e-05 22.7 2.7 0.00011 21.9 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFX98563.1 - 0.0019 17.9 1.7 0.003 17.3 1.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX98563.1 - 0.012 15.2 2.9 0.02 14.5 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX98563.1 - 0.026 14.2 0.7 0.041 13.5 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX98563.1 - 0.055 13.1 0.3 0.055 13.1 0.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_L23 PF00276.15 KFX98564.1 - 6.4e-14 51.6 0.2 1.3e-13 50.6 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.9 KFX98565.1 - 2e-26 92.6 0.0 2.3e-18 66.3 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Mito_carr PF00153.22 KFX98566.1 - 3.2e-65 215.8 0.2 1.1e-22 79.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Ferritin_2 PF13668.1 KFX98567.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Hist_deacetyl PF00850.14 KFX98568.1 - 2.1e-75 253.9 0.0 3e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain CDC45 PF02724.9 KFX98568.1 - 1.3 7.0 3.5 1.8 6.4 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Npa1 PF11707.3 KFX98569.1 - 1.3e-82 277.4 0.0 2.3e-82 276.6 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Longin PF13774.1 KFX98569.1 - 1.9e-22 78.6 0.0 4.4e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFX98569.1 - 5e-15 54.8 0.1 1.2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin Arm PF00514.18 KFX98569.1 - 0.00014 21.5 0.5 0.0015 18.2 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Creb_binding PF09030.5 KFX98569.1 - 0.0082 16.3 0.1 0.3 11.2 0.0 2.9 2 0 0 2 2 2 1 Creb binding S1 PF00575.18 KFX98569.1 - 0.096 12.7 0.1 11 6.1 0.1 2.5 2 0 0 2 2 2 0 S1 RNA binding domain SUV3_C PF12513.3 KFX98570.1 - 1.8e-17 62.4 0.9 3.8e-17 61.4 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KFX98570.1 - 1.4e-08 34.5 0.0 3.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KFX98571.1 - 0.00012 21.6 0.3 0.00033 20.2 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CRAL_TRIO PF00650.15 KFX98572.1 - 1.7e-26 92.5 0.0 2.5e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX98572.1 - 3.1e-12 46.4 0.5 9e-12 44.9 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AIF_C PF14721.1 KFX98572.1 - 0.013 15.7 0.1 0.041 14.1 0.0 1.9 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rad4 PF03835.10 KFX98573.1 - 6.3e-32 109.9 0.3 2.3e-31 108.1 0.2 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KFX98573.1 - 4.7e-28 96.7 0.1 9.4e-28 95.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KFX98573.1 - 6.2e-18 64.0 0.2 2.3e-17 62.2 0.1 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFX98573.1 - 3.1e-15 56.2 0.2 3.1e-15 56.2 0.1 2.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 CorA PF01544.13 KFX98573.1 - 6.1e-14 51.7 4.9 2.2e-11 43.3 0.6 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Transglut_core PF01841.14 KFX98573.1 - 0.019 15.1 0.0 0.067 13.4 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily Kelch_1 PF01344.20 KFX98573.1 - 0.18 11.3 0.2 0.49 9.9 0.2 1.7 1 0 0 1 1 1 0 Kelch motif UPF0104 PF03706.8 KFX98573.1 - 0.27 10.4 0.6 0.43 9.7 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) zf-AN1 PF01428.11 KFX98574.1 - 7.9e-24 83.2 18.8 2.2e-12 46.6 4.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KFX98574.1 - 8.6e-05 22.3 14.7 0.00049 19.9 2.0 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 KFX98574.1 - 0.18 12.0 12.6 0.73 10.0 0.9 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HIT PF01230.18 KFX98575.1 - 3.2e-13 50.0 0.0 9.3e-13 48.5 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFX98575.1 - 0.0038 17.4 0.1 0.026 14.7 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFX98575.1 - 0.011 15.4 1.1 0.035 13.7 0.0 2.1 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 ATP_transf PF09830.4 KFX98575.1 - 0.15 11.8 0.2 18 5.1 0.0 3.0 2 1 1 3 3 3 0 ATP adenylyltransferase DUF2611 PF11022.3 KFX98576.1 - 1.7e-24 85.6 0.0 2.5e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Amino_oxidase PF01593.19 KFX98577.1 - 0.0093 15.0 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase tRNA-synt_1c PF00749.16 KFX98579.1 - 4.2e-96 321.2 0.1 6e-96 320.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFX98579.1 - 4.9e-38 130.5 0.4 1.1e-37 129.4 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KFX98579.1 - 0.0083 15.2 0.6 0.025 13.6 0.4 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DSS1_SEM1 PF05160.8 KFX98579.1 - 0.035 13.8 2.8 0.11 12.2 1.9 1.8 1 0 0 1 1 1 0 DSS1/SEM1 family F-box PF00646.28 KFX98580.1 - 0.0021 17.6 0.3 0.0048 16.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX98580.1 - 0.016 14.8 0.3 0.043 13.5 0.2 1.7 1 0 0 1 1 1 0 F-box-like Trypan_PARP PF05887.6 KFX98582.1 - 0.15 11.8 5.1 0.3 10.9 3.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Paramecium_SA PF01508.11 KFX98582.1 - 2.8 8.2 13.7 0.13 12.5 1.4 2.8 2 1 0 2 2 2 0 Paramecium surface antigen domain Fungal_trans_2 PF11951.3 KFX98583.1 - 6.4e-29 100.7 9.9 1.2e-28 99.8 6.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 KFX98583.1 - 2.2e-23 82.7 0.1 6e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Zn_clus PF00172.13 KFX98583.1 - 0.00017 21.4 3.4 0.00039 20.2 2.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.22 KFX98583.1 - 0.0017 18.6 1.7 0.0042 17.4 1.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX98583.1 - 0.0059 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX98583.1 - 0.02 14.9 0.2 0.055 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX98583.1 - 0.029 14.2 0.4 0.076 12.8 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX98583.1 - 0.26 10.3 0.4 0.43 9.5 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KFX98583.1 - 0.42 9.9 0.5 0.71 9.2 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_4 PF01063.14 KFX98584.1 - 3.7e-37 127.9 0.0 4.5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF2254 PF10011.4 KFX98584.1 - 0.045 12.2 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Aldo_ket_red PF00248.16 KFX98585.1 - 1.7e-65 220.6 0.0 2.1e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 KFX98586.1 - 3.8e-18 65.2 0.0 5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 KFX98587.1 - 8.5e-39 132.8 0.0 1e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 KFX98588.1 - 3.2e-36 124.7 47.0 1.2e-35 122.8 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Laminin_G_2 PF02210.19 KFX98589.1 - 0.00034 20.6 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFX98589.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Glyco_hydro_43 PF04616.9 KFX98590.1 - 7.7e-46 156.4 7.0 8.8e-46 156.2 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Lipase_GDSL_2 PF13472.1 KFX98591.1 - 2.2e-16 60.4 0.6 2.2e-16 60.4 0.4 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX98591.1 - 4.8e-15 56.0 0.7 1.3e-14 54.5 0.5 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Chal_sti_synt_C PF02797.10 KFX98592.1 - 2.2e-23 82.8 0.0 5.8e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 KFX98592.1 - 8.2e-22 77.5 0.2 1.3e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.5 KFX98592.1 - 5.8e-06 26.2 0.0 3.6e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAE1_CUT1_RppA PF08392.7 KFX98592.1 - 1.1e-05 24.7 0.1 1.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 KFX98592.1 - 0.018 14.7 0.3 0.056 13.1 0.2 1.8 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4345 PF14248.1 KFX98593.1 - 0.03 13.7 1.9 0.043 13.2 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) BUD22 PF09073.5 KFX98594.1 - 6.8e-82 275.8 26.5 8.3e-82 275.5 18.4 1.1 1 0 0 1 1 1 1 BUD22 DUF2945 PF11160.3 KFX98595.1 - 8e-14 51.2 0.0 2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Sugar_tr PF00083.19 KFX98596.1 - 2.6e-123 411.9 26.8 3e-123 411.7 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98596.1 - 2.8e-26 92.0 54.9 2.7e-24 85.5 20.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX98596.1 - 2.3e-05 22.9 6.1 2.3e-05 22.9 4.3 3.3 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX98596.1 - 0.024 12.8 9.1 0.016 13.4 2.3 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KFX98596.1 - 0.13 12.0 0.1 0.13 12.0 0.1 4.0 5 0 0 5 5 5 0 MFS_1 like family Phage_holin_2 PF04550.7 KFX98596.1 - 0.14 12.3 3.9 0.48 10.5 2.7 1.9 1 0 0 1 1 1 0 Phage holin family 2 PI3_PI4_kinase PF00454.22 KFX98607.1 - 3e-42 144.7 0.0 2.4e-40 138.5 0.0 2.8 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFX98607.1 - 4e-23 81.5 0.1 3.6e-22 78.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.21 KFX98608.1 - 9.6e-29 100.0 0.2 1.8e-28 99.1 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit C2 PF00168.25 KFX98609.1 - 1.8e-08 34.1 0.0 4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain 4HBT_3 PF13622.1 KFX98611.1 - 5.6e-47 160.6 0.0 6.7e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KFX98611.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily HMA PF00403.21 KFX98620.1 - 2.7e-06 27.4 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain CN_hydrolase PF00795.17 KFX98623.1 - 7.1e-31 106.9 0.0 9.4e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CENP-C_C PF11699.3 KFX98627.1 - 9.3e-31 105.6 0.0 1.4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KFX98627.1 - 7.1e-28 97.8 1.2 7.1e-28 97.8 0.8 3.4 3 0 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KFX98627.1 - 2e-10 39.9 0.0 3.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KFX98627.1 - 0.0005 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KFX98627.1 - 0.017 14.5 0.0 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KFX98627.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Cupin Fructosamin_kin PF03881.9 KFX98628.1 - 4.5e-72 242.4 0.0 5.4e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFX98628.1 - 1.8e-05 24.5 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFX98628.1 - 0.0087 14.7 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) TAF4 PF05236.9 KFX98629.1 - 9.3e-16 57.8 0.0 1.4e-12 47.4 0.0 3.2 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 KFX98630.1 - 3.4e-75 252.0 0.0 1.5e-72 243.4 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KFX98630.1 - 5.4e-33 113.6 0.0 2.5e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KFX98630.1 - 6.6e-15 55.2 0.4 6.6e-15 55.2 0.3 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX98630.1 - 5e-11 42.5 0.4 1.1e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KFX98630.1 - 1.2e-07 31.4 0.3 2.3e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KFX98630.1 - 7.2e-05 22.5 0.1 0.00019 21.1 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CN_hydrolase PF00795.17 KFX98631.1 - 1.9e-23 82.8 0.0 4.5e-23 81.5 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Mito_carr PF00153.22 KFX98632.1 - 5.2e-56 186.3 2.0 9e-20 70.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.15 KFX98634.1 - 9.3e-20 70.3 3.7 1.2e-19 70.0 2.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Atg14 PF10186.4 KFX98634.1 - 0.038 12.9 4.3 1.8 7.4 0.0 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KFX98634.1 - 0.039 13.8 4.9 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding USP8_interact PF08941.5 KFX98634.1 - 0.045 13.0 0.6 0.045 13.0 0.4 1.6 2 0 0 2 2 2 0 USP8 interacting GM_CSF PF01109.12 KFX98634.1 - 0.096 12.6 1.0 0.23 11.3 0.2 1.7 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Fib_alpha PF08702.5 KFX98634.1 - 0.13 12.3 6.8 2.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 KFX98634.1 - 0.14 12.3 6.3 3.3 7.9 4.4 2.0 1 1 0 1 1 1 0 Syntaxin Tropomyosin_1 PF12718.2 KFX98634.1 - 0.16 11.7 4.0 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Striatin PF08232.7 KFX98634.1 - 0.21 11.9 2.4 7.5 6.8 0.1 2.0 2 0 0 2 2 2 0 Striatin family DUF1640 PF07798.6 KFX98634.1 - 0.29 11.1 5.3 1.4 8.9 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.17 KFX98634.1 - 0.33 10.9 5.4 6.8 6.7 1.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KFX98634.1 - 0.35 9.4 6.0 4.3 5.8 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2681 PF10883.3 KFX98634.1 - 0.41 10.8 5.1 7.9 6.7 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TBPIP PF07106.8 KFX98634.1 - 0.62 9.5 7.7 3.1 7.3 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 KFX98634.1 - 0.73 10.0 4.2 13 6.0 0.1 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Tektin PF03148.9 KFX98634.1 - 0.73 8.3 5.8 3 6.2 0.1 2.0 2 0 0 2 2 2 0 Tektin family Uds1 PF15456.1 KFX98634.1 - 0.75 9.7 4.3 4.9 7.1 3.0 1.9 1 1 0 1 1 1 0 Up-regulated During Septation FlxA PF14282.1 KFX98634.1 - 0.87 9.5 13.7 19 5.2 0.0 2.5 2 1 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.6 KFX98634.1 - 0.87 9.0 7.4 2.2 7.6 0.3 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 OEP PF02321.13 KFX98634.1 - 0.92 9.0 6.3 17 4.9 2.7 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein FliD_C PF07195.7 KFX98634.1 - 1.1 8.5 6.4 27 3.9 4.5 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.4 KFX98634.1 - 1.3 9.2 5.7 1.3 9.2 0.1 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 KFX98634.1 - 1.5 8.6 7.1 6.3 6.5 3.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 KFX98634.1 - 1.6 8.0 7.6 3.9 6.7 2.3 2.0 2 0 0 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.3 KFX98634.1 - 2.5 7.9 7.7 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KFX98634.1 - 2.8 8.3 6.8 1.4e+02 2.8 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 KFX98635.1 - 8.5e-40 135.2 10.5 8.5e-40 135.2 7.3 5.9 3 2 3 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KFX98635.1 - 2.3e-18 65.7 13.5 2.3e-18 65.7 9.3 7.7 5 3 2 7 7 7 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KFX98635.1 - 0.00095 18.4 21.2 0.02 14.1 1.8 3.6 3 1 0 3 3 3 3 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KFX98635.1 - 0.0016 18.3 17.0 0.0016 18.3 11.8 5.2 3 1 2 5 5 5 1 Tropomyosin like Filament PF00038.16 KFX98635.1 - 0.0048 16.4 76.1 0.015 14.7 19.3 4.2 2 1 2 4 4 4 3 Intermediate filament protein Sterile PF03015.14 KFX98635.1 - 0.016 15.4 0.1 0.057 13.6 0.1 1.9 1 0 0 1 1 1 0 Male sterility protein Ank_2 PF12796.2 KFX98636.1 - 2e-48 162.6 0.7 2.2e-19 69.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX98636.1 - 1.1e-38 129.0 0.3 6.8e-08 31.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFX98636.1 - 2.4e-38 129.2 1.6 7.9e-09 35.4 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX98636.1 - 8e-38 128.1 6.8 1.5e-08 34.9 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX98636.1 - 3e-31 104.3 0.1 0.00025 21.0 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.27 KFX98637.1 - 1.1e-52 174.0 10.8 6e-10 38.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX98637.1 - 0.00014 20.1 4.0 5 5.1 0.0 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX98637.1 - 0.14 10.8 0.0 13 4.4 0.0 2.7 1 1 1 2 2 2 0 Nup133 N terminal like AAA PF00004.24 KFX98638.1 - 1.8e-14 54.0 0.0 5e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX98638.1 - 1.8e-10 41.0 0.0 1.1e-09 38.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 KFX98638.1 - 1.8e-09 37.3 0.0 1.7e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.1 KFX98638.1 - 2.3e-09 37.4 0.0 2.5e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFX98638.1 - 9.2e-05 23.2 0.2 0.0015 19.3 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KFX98638.1 - 0.0018 17.9 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KFX98638.1 - 0.0034 16.4 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KFX98638.1 - 0.0043 16.6 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFX98638.1 - 0.0091 15.7 0.0 0.075 12.7 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase TAFII28 PF04719.9 KFX98638.1 - 0.0096 15.7 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 hTAFII28-like protein conserved region AAA_18 PF13238.1 KFX98638.1 - 0.011 16.0 0.0 0.04 14.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KFX98638.1 - 0.017 14.7 0.0 0.054 13.1 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_32 PF13654.1 KFX98638.1 - 0.019 13.6 0.0 0.036 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX98638.1 - 0.026 14.7 0.1 0.41 10.8 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 KFX98638.1 - 0.029 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KFX98638.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Prefoldin PF02996.12 KFX98640.1 - 6.4e-26 90.3 0.1 8.8e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KFX98640.1 - 0.0035 17.0 2.0 0.41 10.4 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit Sec2p PF06428.6 KFX98640.1 - 0.013 15.3 2.5 0.17 11.7 0.3 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CCDC155 PF14662.1 KFX98640.1 - 0.017 14.7 0.5 0.017 14.7 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Cep57_MT_bd PF06657.8 KFX98640.1 - 0.027 14.4 0.5 0.058 13.3 0.3 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Baculo_PEP_C PF04513.7 KFX98640.1 - 0.044 13.5 0.8 0.27 11.0 0.1 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KFX98640.1 - 0.097 12.4 0.8 9.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KFX98640.1 - 0.14 12.2 0.5 13 5.8 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family tRNA-synt_2b PF00587.20 KFX98641.1 - 4.3e-34 117.5 0.0 5.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX98641.1 - 5.1e-11 42.3 0.0 9.1e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 KFX98642.1 - 1e-47 161.6 0.1 3.4e-47 159.9 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family 4HBT PF03061.17 KFX98643.1 - 5.3e-11 42.4 0.0 9.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily CASP_C PF08172.7 KFX98650.1 - 4.3e-86 287.9 0.9 4.3e-86 287.9 0.6 3.7 2 1 0 2 2 2 1 CASP C terminal DUF904 PF06005.7 KFX98650.1 - 0.05 13.9 0.3 0.05 13.9 0.2 6.6 3 2 0 3 3 3 0 Protein of unknown function (DUF904) UPF0184 PF03670.8 KFX98650.1 - 0.054 13.6 9.1 0.78 9.9 0.3 3.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Mit_KHE1 PF10173.4 KFX98650.1 - 0.37 10.6 3.9 0.88 9.3 2.7 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Cortex-I_coil PF09304.5 KFX98650.1 - 0.81 9.7 44.3 0.75 9.8 2.8 5.4 4 1 1 5 5 5 0 Cortexillin I, coiled coil Laminin_I PF06008.9 KFX98650.1 - 1.1 8.4 39.8 0.0098 15.2 8.6 3.7 3 2 0 3 3 3 0 Laminin Domain I Tri3 PF07428.6 KFX98651.1 - 1.2e-10 40.6 0.0 4.9e-10 38.6 0.0 1.8 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.7 KFX98651.1 - 0.0052 15.3 0.0 0.023 13.2 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KFX98651.1 - 0.02 13.7 0.2 0.28 9.9 0.0 2.5 2 1 1 3 3 3 0 Condensation domain AMP-binding PF00501.23 KFX98652.1 - 6.7e-242 802.1 0.0 2.4e-86 289.7 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFX98652.1 - 2e-141 470.1 0.0 4.9e-40 137.2 0.6 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KFX98652.1 - 9.3e-32 109.1 0.2 6.7e-11 42.3 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site PS_Dcarbxylase PF02666.10 KFX98653.1 - 1.5e-20 73.3 0.0 1.7e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MFS_1 PF07690.11 KFX98654.1 - 2.4e-06 26.5 19.5 2.6e-06 26.4 6.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 KFX98655.1 - 2.1e-25 89.4 0.0 3.8e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cas_CXXC_CXXC PF09706.5 KFX98655.1 - 0.04 14.1 1.7 4.9 7.4 0.1 2.7 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) ArabFuran-catal PF09206.6 KFX98656.1 - 1.4e-141 471.1 23.5 2e-141 470.6 16.3 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KFX98656.1 - 5.2e-56 188.3 1.2 8.7e-56 187.5 0.8 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) NDK PF00334.14 KFX98690.1 - 1.8e-53 179.9 0.0 2.2e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 KFX98691.1 - 4.4e-155 516.8 3.3 6.2e-155 516.3 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX98691.1 - 9.6e-24 83.0 2.3 1e-23 82.9 0.3 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Ank_2 PF12796.2 KFX98692.1 - 6.3e-44 148.2 7.5 1.1e-16 60.9 0.2 8.2 6 2 3 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX98692.1 - 8.7e-33 110.4 14.1 2.3e-06 27.1 0.0 11.5 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 KFX98692.1 - 1.1e-28 98.5 4.9 0.0021 18.2 0.0 9.0 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX98692.1 - 1.3e-28 96.1 0.3 0.00049 20.0 0.0 11.9 13 0 0 13 13 13 5 Ankyrin repeat Ank_4 PF13637.1 KFX98692.1 - 9e-25 86.5 5.5 5.2e-05 23.6 0.2 9.6 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Sema PF01403.14 KFX98692.1 - 0.14 10.6 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Sema domain P19Arf_N PF07392.7 KFX98692.1 - 0.25 11.5 0.0 0.64 10.2 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Phage_GPO PF05929.6 KFX98695.1 - 0.018 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1631 PF07793.6 KFX98695.1 - 0.031 12.4 0.2 0.04 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Baculo_PEP_C PF04513.7 KFX98695.1 - 0.28 11.0 1.3 3.1 7.6 0.9 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.1 KFX98695.1 - 0.53 10.4 2.4 3.2 7.9 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HMA PF00403.21 KFX98696.1 - 4.3e-14 52.3 0.5 6e-14 51.9 0.1 1.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Tcf25 PF04910.9 KFX98697.1 - 4.1e-77 259.5 0.1 4.1e-77 259.5 0.0 2.1 2 0 0 2 2 2 1 Transcriptional repressor TCF25 PP2C PF00481.16 KFX98698.1 - 1.2e-37 129.7 0.0 2.1e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFX98698.1 - 0.0025 17.2 0.0 0.0062 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFX98698.1 - 0.0067 16.1 0.0 1.8 8.1 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) DUF3954 PF13128.1 KFX98698.1 - 0.079 12.3 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) adh_short PF00106.20 KFX98700.1 - 7.8e-21 74.6 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX98700.1 - 3.9e-10 39.9 0.0 5.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX98700.1 - 0.00024 20.7 0.0 0.00057 19.5 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX98700.1 - 0.0036 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX98700.1 - 0.042 12.7 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3886 PF13025.1 KFX98701.1 - 0.063 13.2 6.3 0.11 12.4 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) ketoacyl-synt PF00109.21 KFX98702.1 - 1.5e-72 244.1 0.2 3.2e-72 243.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX98702.1 - 1.6e-30 106.5 0.1 1.5e-29 103.3 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFX98702.1 - 3.4e-29 101.0 0.1 9e-29 99.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFX98702.1 - 4.7e-28 97.7 0.0 1e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KFX98702.1 - 3.6e-14 53.0 0.0 1.4e-13 51.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX98702.1 - 4.1e-11 42.7 0.0 8.6e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFX98702.1 - 2.8e-09 37.0 0.9 7.7e-09 35.6 0.7 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KFX98702.1 - 4.2e-09 36.7 0.0 1.3e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX98702.1 - 4.7e-09 36.1 0.0 2.1e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX98702.1 - 3.7e-07 30.6 0.0 1.4e-06 28.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KFX98702.1 - 4.5e-07 29.5 0.0 8.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 KFX98702.1 - 5.3e-06 25.6 0.0 1.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KFX98702.1 - 8.1e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KFX98702.1 - 0.00012 21.3 0.0 0.00033 19.8 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KFX98702.1 - 0.00028 20.3 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 KFX98702.1 - 0.0003 20.8 0.0 0.00095 19.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KFX98702.1 - 0.00045 20.1 0.0 0.00098 19.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX98702.1 - 0.00049 19.8 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 KFX98702.1 - 0.0006 20.1 0.0 0.0032 17.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KFX98702.1 - 0.0015 17.4 0.0 0.0084 15.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RrnaAD PF00398.15 KFX98702.1 - 0.0016 17.5 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RmlD_sub_bind PF04321.12 KFX98702.1 - 0.0052 15.7 0.0 0.57 9.0 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain Methyltransf_28 PF02636.12 KFX98702.1 - 0.0089 15.4 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 KFX98702.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dh PF01118.19 KFX98702.1 - 0.14 12.5 0.1 3.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain FSH1 PF03959.8 KFX98703.1 - 9.7e-28 97.0 0.0 1.3e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFX98703.1 - 0.0003 20.5 0.1 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX98703.1 - 0.0013 18.2 0.3 0.02 14.3 0.1 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFX98703.1 - 0.0028 17.5 3.5 0.0064 16.3 2.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transferase PF02458.10 KFX98704.1 - 1.8e-28 99.2 0.0 6.4e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 Transferase family FAD_binding_3 PF01494.14 KFX98705.1 - 7.6e-19 67.9 6.9 1.2e-12 47.6 1.6 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX98705.1 - 4.4e-07 29.1 0.9 2.6e-06 26.6 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX98705.1 - 0.00031 20.7 0.8 0.0008 19.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX98705.1 - 0.0048 15.7 1.4 0.029 13.2 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX98705.1 - 0.0072 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX98705.1 - 0.014 15.7 0.6 0.032 14.6 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX98705.1 - 0.06 12.2 0.5 2.3 7.0 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFX98705.1 - 0.13 12.3 0.3 0.54 10.2 0.2 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFX98705.1 - 0.2 11.0 0.5 0.41 10.0 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 KFX98706.1 - 1.5e-11 44.1 0.6 3.4e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFX98706.1 - 3.2e-08 33.0 0.4 5.4e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX98706.1 - 1.8e-05 23.8 1.2 2.7e-05 23.2 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFX98706.1 - 1.9e-05 24.9 0.1 4.2e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX98706.1 - 3.4e-05 22.5 0.7 5.2e-05 21.8 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KFX98706.1 - 5e-05 22.3 1.3 0.00013 21.0 0.9 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX98706.1 - 0.00016 21.6 0.3 0.00028 20.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX98706.1 - 0.00027 21.0 0.1 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFX98706.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.17 KFX98706.1 - 0.005 15.7 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFX98706.1 - 0.0057 15.7 0.1 0.0091 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 KFX98706.1 - 0.019 14.4 0.9 0.04 13.3 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KFX98706.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family ADH_zinc_N PF00107.21 KFX98707.1 - 1.8e-09 37.1 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX98707.1 - 5.6e-09 35.7 0.1 1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KFX98708.1 - 3.2e-52 177.6 0.0 4.2e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 KFX98709.1 - 7e-17 62.1 0.7 8.5e-17 61.8 0.5 1.1 1 0 0 1 1 1 1 EthD domain DUF1284 PF06935.6 KFX98710.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) Zn_clus PF00172.13 KFX98711.1 - 2.4e-07 30.5 9.4 2.4e-07 30.5 6.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 KFX98712.1 - 3e-71 239.8 0.2 1.1e-70 238.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFX98712.1 - 1.5e-57 194.2 2.6 2.3e-57 193.6 0.1 2.6 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KFX98712.1 - 4.1e-55 187.3 0.0 7.8e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFX98712.1 - 1.8e-49 168.5 0.0 1.2e-48 165.8 0.0 2.1 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFX98712.1 - 6.7e-45 152.9 0.8 4.8e-43 146.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFX98712.1 - 8.3e-38 128.8 0.5 3.8e-37 126.7 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KFX98712.1 - 7e-06 26.2 0.0 2.3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 KFX98712.1 - 0.00029 20.3 0.1 0.0011 18.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KFX98712.1 - 0.021 14.7 1.1 8 6.4 0.1 2.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ACP_syn_III PF08545.5 KFX98712.1 - 0.027 14.1 0.8 0.33 10.6 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KFX98712.1 - 0.048 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain YflT PF11181.3 KFX98712.1 - 0.086 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT DUF915 PF06028.6 KFX98712.1 - 0.21 10.6 0.0 0.5 9.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Epimerase PF01370.16 KFX98713.1 - 1.9e-15 56.9 0.0 2.6e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX98713.1 - 4.7e-14 51.7 0.0 8.9e-14 50.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX98713.1 - 7.3e-13 48.9 0.1 1.1e-12 48.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX98713.1 - 7.1e-10 38.2 0.4 2.6e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KFX98713.1 - 5.5e-07 29.0 0.1 8e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KFX98713.1 - 0.0002 20.4 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX98713.1 - 0.0072 15.2 0.6 0.14 11.0 0.4 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KFX98713.1 - 0.02 14.8 1.3 0.11 12.3 0.6 2.3 1 1 1 2 2 2 0 short chain dehydrogenase KR PF08659.5 KFX98713.1 - 0.31 10.6 2.7 14 5.3 0.1 2.6 2 1 0 2 2 2 0 KR domain F420_oxidored PF03807.12 KFX98714.1 - 7.2e-09 35.9 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 KFX98714.1 - 0.0036 17.0 0.1 0.025 14.2 0.0 2.1 1 1 0 1 1 1 1 Rossmann-like domain B12-binding PF02310.14 KFX98714.1 - 0.029 14.2 0.0 0.13 12.0 0.0 2.2 2 1 1 3 3 3 0 B12 binding domain ADH_zinc_N PF00107.21 KFX98717.1 - 8.3e-17 60.9 0.0 1.6e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX98717.1 - 1.1e-06 28.3 1.7 3.4e-06 26.7 0.0 2.6 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain CAP59_mtransfer PF11735.3 KFX98718.1 - 3.8e-63 212.9 0.0 5.3e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Amidohydro_1 PF01979.15 KFX98719.1 - 1.2e-34 120.4 0.1 1.2e-34 120.4 0.0 1.6 2 0 0 2 2 2 1 Amidohydrolase family PPR_2 PF13041.1 KFX98719.1 - 1.8e-20 72.6 8.5 3e-06 27.1 0.1 8.2 6 2 5 11 11 11 4 PPR repeat family PPR_3 PF13812.1 KFX98719.1 - 1e-19 69.0 5.4 0.0046 17.1 0.0 10.6 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 KFX98719.1 - 6.5e-12 44.5 9.6 0.24 11.4 0.0 9.4 10 0 0 10 10 10 4 PPR repeat Amidohydro_3 PF07969.6 KFX98719.1 - 1.1e-10 41.3 0.0 2.9e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.13 KFX98719.1 - 1.6e-07 31.1 9.3 2.7e-07 30.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_4 PF13147.1 KFX98719.1 - 2.5e-06 27.7 0.5 8.7e-05 22.6 0.4 2.8 1 1 0 1 1 1 1 Amidohydrolase PPR_1 PF12854.2 KFX98719.1 - 1e-05 24.9 0.1 0.37 10.2 0.0 4.6 4 0 0 4 4 4 1 PPR repeat Amidohydro_5 PF13594.1 KFX98719.1 - 0.00017 21.2 0.1 0.00051 19.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase ECSIT PF06239.6 KFX98719.1 - 0.027 13.3 0.1 0.24 10.2 0.0 2.3 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Fungal_trans PF04082.13 KFX98719.1 - 0.059 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_1 PF00515.23 KFX98719.1 - 2.2 8.0 6.1 32 4.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98719.1 - 5.3 7.0 6.2 47 4.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PMEI PF04043.10 KFX98720.1 - 0.0035 17.2 1.3 0.012 15.4 0.9 1.9 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor DIE2_ALG10 PF04922.7 KFX98721.1 - 8.3e-42 143.5 0.0 1.2e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family GalP_UDP_transf PF01087.17 KFX98722.1 - 7.1e-71 238.0 0.1 8.4e-69 231.2 0.1 2.1 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KFX98722.1 - 3.1e-56 189.5 0.0 6.2e-56 188.5 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KFX98722.1 - 0.0016 18.9 0.0 0.05 14.1 0.0 2.3 2 0 0 2 2 2 1 HIT domain Sld5 PF05916.6 KFX98724.1 - 9.3e-09 35.5 0.1 1.8e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein Glyco_transf_90 PF05686.7 KFX98724.1 - 1.2e-06 27.5 0.0 4.4e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 S-methyl_trans PF02574.11 KFX98725.1 - 7.4e-27 94.4 0.0 9.5e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peripla_BP_4 PF13407.1 KFX98725.1 - 0.0025 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.1 KFX98725.1 - 0.041 13.2 0.1 0.059 12.7 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein MR_MLE_C PF13378.1 KFX98725.1 - 0.048 13.6 0.1 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like PGM_PMM_I PF02878.11 KFX98725.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Peptidase_M24 PF00557.19 KFX98726.1 - 5.9e-35 120.7 0.3 8.5e-35 120.2 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PP_kinase_N PF13089.1 KFX98726.1 - 0.12 12.4 0.1 0.51 10.4 0.0 2.0 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain GST_C PF00043.20 KFX98727.1 - 4.5e-09 36.1 0.0 9.2e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX98727.1 - 0.00092 19.6 0.0 0.0019 18.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX98727.1 - 0.011 15.5 0.1 0.019 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX98727.1 - 0.024 14.8 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 KFX98728.1 - 1e-49 169.1 35.3 1e-49 169.1 24.5 3.2 4 0 0 4 4 4 1 Major Facilitator Superfamily Ferric_reduct PF01794.14 KFX98728.1 - 7.9e-16 58.2 12.0 7.9e-16 58.2 8.3 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Sugar_tr PF00083.19 KFX98728.1 - 2.6e-14 52.6 18.5 2.6e-14 52.6 12.8 2.8 2 0 0 2 2 2 1 Sugar (and other) transporter FAD_binding_8 PF08022.7 KFX98728.1 - 5.5e-12 45.4 0.0 3.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 KFX98728.1 - 0.00067 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Octopine_DH PF02317.12 KFX98729.1 - 1.8e-39 134.8 0.0 2.6e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 KFX98729.1 - 1e-11 44.8 0.0 1.7e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KFX98729.1 - 1.4e-05 25.4 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.9 KFX98729.1 - 0.00069 19.5 0.0 0.00075 19.4 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX98729.1 - 0.0024 16.8 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KFX98729.1 - 0.0043 17.1 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX98729.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX98729.1 - 0.0058 15.1 0.0 0.012 14.1 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFX98729.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 KFX98729.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KFX98729.1 - 0.038 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX98729.1 - 0.048 12.4 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Rossmann-like PF10727.4 KFX98729.1 - 0.09 12.5 0.1 0.37 10.5 0.1 2.0 1 1 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.10 KFX98729.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFX98729.1 - 0.13 11.4 0.0 0.94 8.6 0.0 2.2 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFX98729.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 KFX98730.1 - 4.6e-24 84.7 0.0 6.5e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX98730.1 - 1.3e-23 83.3 0.0 2.4e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX98730.1 - 2.5e-16 59.5 0.0 1e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KFX98730.1 - 5.9e-16 58.6 0.0 8.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX98730.1 - 1.4e-15 57.7 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX98730.1 - 2.2e-14 53.6 0.0 3.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX98730.1 - 3.1e-14 53.2 0.0 5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX98730.1 - 8.5e-10 38.2 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX98730.1 - 1.5e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX98730.1 - 7.9e-08 32.0 0.0 1.9e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFX98730.1 - 2.5e-06 26.7 0.0 3.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 KFX98730.1 - 5.7e-06 27.1 0.0 1.1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX98730.1 - 6.9e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Fibrillarin PF01269.12 KFX98730.1 - 0.00044 19.2 0.0 0.00065 18.6 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_4 PF02390.12 KFX98730.1 - 0.0018 17.3 0.0 0.014 14.4 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 KFX98730.1 - 0.0034 15.8 0.0 0.0044 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.14 KFX98730.1 - 0.0054 16.7 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.5 KFX98730.1 - 0.0072 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 KFX98730.1 - 0.01 14.9 0.2 0.019 14.0 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Nol1_Nop2_Fmu PF01189.12 KFX98730.1 - 0.016 14.6 0.0 0.041 13.2 0.0 1.6 1 1 0 1 1 1 0 NOL1/NOP2/sun family ADH_zinc_N PF00107.21 KFX98730.1 - 0.023 14.2 0.1 0.16 11.5 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.15 KFX98730.1 - 0.028 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 KFX98730.1 - 0.028 13.1 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TrkA_N PF02254.13 KFX98730.1 - 0.038 13.9 0.1 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_32 PF13679.1 KFX98730.1 - 0.039 13.6 0.0 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.8 KFX98730.1 - 0.052 12.8 0.0 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 KFX98730.1 - 0.065 12.8 0.1 0.26 10.8 0.1 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase p450 PF00067.17 KFX98731.1 - 2.7e-77 260.2 0.0 3.5e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane_3 PF13748.1 KFX98731.1 - 0.037 13.0 0.0 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region G6PD_N PF00479.17 KFX98731.1 - 0.18 12.0 0.4 0.41 10.8 0.1 1.6 2 0 0 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Cupin_1 PF00190.17 KFX98733.1 - 5e-29 100.5 0.0 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KFX98733.1 - 3.3e-23 80.9 1.1 1.3e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFX98733.1 - 1.9e-08 33.5 0.0 0.0036 16.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KFX98733.1 - 7.6e-07 28.9 0.1 0.014 14.9 0.0 2.6 2 1 1 3 3 3 2 Cupin AraC_binding PF02311.14 KFX98733.1 - 1.5e-05 24.7 0.3 0.041 13.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain 2OG-FeII_Oxy_5 PF13759.1 KFX98733.1 - 0.038 14.2 0.2 79 3.6 0.0 3.7 2 2 2 4 4 4 0 Putative 2OG-Fe(II) oxygenase SBP56 PF05694.6 KFX98734.1 - 1.9e-06 26.6 0.0 0.00023 19.7 0.0 3.1 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFX98734.1 - 0.012 14.6 0.1 2.2 7.3 0.1 2.7 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KFX98734.1 - 0.031 13.6 0.1 1.8 7.8 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Nup160 PF11715.3 KFX98734.1 - 0.046 11.8 0.0 0.066 11.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NHL PF01436.16 KFX98734.1 - 0.063 13.2 0.3 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 NHL repeat MR_MLE_C PF13378.1 KFX98735.1 - 1.8e-34 118.0 0.1 4.6e-34 116.7 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KFX98735.1 - 6.4e-20 71.3 0.0 1.3e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KFX98735.1 - 1.1e-08 35.4 0.0 3.4e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Esterase_phd PF10503.4 KFX98736.1 - 1e-20 73.9 0.9 1.3e-20 73.6 0.6 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX98736.1 - 9.1e-13 47.9 0.5 1.7e-12 47.0 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX98736.1 - 1.9e-08 34.1 0.2 2.6e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX98736.1 - 4.2e-06 26.8 0.5 2.9e-05 24.0 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX98736.1 - 6.8e-05 22.4 1.1 0.00071 19.0 0.8 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 KFX98736.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFX98736.1 - 0.0014 18.2 0.2 0.0017 17.9 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFX98736.1 - 0.0026 17.3 0.2 0.0043 16.6 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFX98736.1 - 0.0027 17.1 0.6 0.0079 15.6 0.4 1.8 1 1 0 1 1 1 1 Putative esterase DUF2235 PF09994.4 KFX98736.1 - 0.092 12.1 0.2 0.29 10.4 0.0 1.7 1 1 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) AXE1 PF05448.7 KFX98736.1 - 0.14 10.5 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RNase_H PF00075.19 KFX98737.1 - 1.5e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KFX98737.1 - 0.00014 21.6 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like Glyco_transf_8 PF01501.15 KFX98738.1 - 1.5e-11 44.1 0.1 3.7e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Ricin_B_lectin PF00652.17 KFX98739.1 - 7.2e-20 71.2 0.6 1.3e-19 70.4 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.13 KFX98739.1 - 5.1e-18 64.9 0.0 7.1e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 Melibiase RicinB_lectin_2 PF14200.1 KFX98739.1 - 0.015 15.7 0.1 0.2 12.0 0.0 2.7 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 KFX98739.1 - 0.017 14.5 1.9 2.8 7.2 0.1 2.8 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family Aldo_ket_red PF00248.16 KFX98746.1 - 1.8e-49 168.0 0.0 2.1e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 KFX98747.1 - 1.4e-42 142.6 38.6 2.5e-10 39.7 1.2 6.7 4 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX98747.1 - 6.9e-27 92.9 58.1 7e-08 32.1 1.8 5.0 1 1 6 7 7 7 6 Leucine rich repeat LRR_9 PF14580.1 KFX98747.1 - 3.4e-13 49.5 8.5 9.6e-05 22.0 1.2 3.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 KFX98747.1 - 1.6e-12 46.1 22.1 0.04 13.9 0.4 10.3 7 4 3 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.28 KFX98747.1 - 1.4e-11 42.7 24.0 0.44 10.7 0.1 10.9 11 1 0 11 11 11 5 Leucine Rich Repeat LRR_7 PF13504.1 KFX98747.1 - 6.2e-08 31.5 15.0 1.1 9.7 0.1 9.8 9 1 0 9 9 9 1 Leucine rich repeat BTB PF00651.26 KFX98748.1 - 3.7e-08 33.3 0.0 1.3e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 KFX98748.1 - 0.12 12.4 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain PCI PF01399.22 KFX98749.1 - 1.2e-09 38.3 0.0 4.4e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain OTCace_N PF02729.16 KFX98749.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ribosomal_L18ae PF01775.12 KFX98750.1 - 5.1e-60 200.8 0.7 6.5e-60 200.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain SAD_SRA PF02182.12 KFX98751.1 - 3.1e-22 78.5 0.1 5.4e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain AMP-binding PF00501.23 KFX98753.1 - 9.1e-80 268.0 0.0 2e-79 266.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KFX98753.1 - 2.5e-74 249.9 0.0 5e-74 248.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFX98753.1 - 3.9e-53 179.8 0.4 9.4e-52 175.2 0.1 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KFX98753.1 - 9.7e-52 176.2 0.0 1.8e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFX98753.1 - 1.2e-51 175.7 0.0 1.9e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 KFX98753.1 - 8.6e-48 162.7 0.0 2.2e-47 161.3 0.0 1.8 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KFX98753.1 - 2.4e-46 157.7 0.1 1.5e-42 145.3 0.0 3.0 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 KFX98753.1 - 1.3e-42 145.4 0.0 3.5e-42 144.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein MFS_1 PF07690.11 KFX98753.1 - 2.2e-41 141.7 48.3 2.2e-41 141.7 33.5 1.8 2 0 0 2 2 1 1 Major Facilitator Superfamily Ketoacyl-synt_C PF02801.17 KFX98753.1 - 4.2e-30 104.0 0.0 1.3e-29 102.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 KFX98753.1 - 1.8e-24 86.5 0.0 3.3e-17 62.7 0.0 3.6 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 KFX98753.1 - 4.4e-20 72.0 0.0 1.6e-19 70.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFX98753.1 - 6.6e-17 61.5 1.9 1.3e-10 41.3 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KFX98753.1 - 2.4e-15 56.4 0.1 9.5e-15 54.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX98753.1 - 3.6e-15 56.0 0.0 8.7e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX98753.1 - 3.6e-15 56.2 0.0 9.2e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KFX98753.1 - 7.9e-14 51.0 0.0 8.9e-10 37.7 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 KFX98753.1 - 1.8e-12 46.5 12.1 1.8e-12 46.5 8.4 2.3 2 0 0 2 2 1 1 Sugar (and other) transporter Methyltransf_18 PF12847.2 KFX98753.1 - 7.7e-11 42.5 0.0 7.7e-10 39.3 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX98753.1 - 6.6e-10 38.5 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HxxPF_rpt PF13745.1 KFX98753.1 - 9.1e-10 38.7 0.0 2.7e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_25 PF13649.1 KFX98753.1 - 3.2e-08 33.8 0.0 1.2e-07 31.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KFX98753.1 - 3.6e-05 22.8 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KFX98753.1 - 5e-05 22.8 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NAD_binding_10 PF13460.1 KFX98753.1 - 0.0002 21.4 0.0 0.012 15.6 0.0 2.8 2 0 0 2 2 2 1 NADH(P)-binding MFS_3 PF05977.8 KFX98753.1 - 0.0029 15.8 9.9 0.0046 15.1 6.9 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Methyltransf_26 PF13659.1 KFX98753.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFX98753.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.15 KFX98753.1 - 0.052 12.5 0.0 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Semialdhyde_dh PF01118.19 KFX98753.1 - 0.092 13.0 0.2 0.94 9.7 0.0 2.8 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain NodS PF05401.6 KFX98753.1 - 0.24 10.7 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 KFX98753.1 - 0.62 8.9 0.0 5 6.0 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Zn_clus PF00172.13 KFX98754.1 - 3.3e-05 23.6 9.1 6.2e-05 22.8 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KFX98755.1 - 2e-62 211.2 0.0 2.6e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.14 KFX98756.1 - 2.3e-41 141.6 0.0 3.8e-21 74.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX98756.1 - 2.8e-15 56.9 1.2 6.3e-14 52.5 0.5 2.8 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX98756.1 - 3.6e-09 36.7 0.0 0.0012 18.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX98756.1 - 4.2e-09 36.3 0.3 1.4e-06 28.2 0.9 3.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KFX98756.1 - 1.1e-08 34.3 2.8 0.024 13.5 1.5 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFX98756.1 - 2e-08 33.7 0.3 5.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KFX98756.1 - 2.7e-08 34.1 0.7 0.00041 20.6 0.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX98756.1 - 4.2e-07 29.8 0.0 2.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFX98756.1 - 1.2e-05 24.3 1.5 4.8e-05 22.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFX98756.1 - 7.6e-05 21.9 0.7 0.00015 20.9 0.5 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KFX98756.1 - 0.0031 16.0 1.0 0.006 15.1 0.7 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFX98756.1 - 0.013 14.5 1.6 0.022 13.8 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 KFX98756.1 - 0.031 13.3 0.1 0.12 11.4 0.0 1.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KFX98756.1 - 0.063 12.4 0.0 7.1 5.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFX98756.1 - 0.074 12.8 0.1 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Metallophos_2 PF12850.2 KFX98756.1 - 0.084 12.7 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Shikimate_DH PF01488.15 KFX98756.1 - 0.16 12.0 0.3 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KFX98756.1 - 0.17 11.2 0.3 0.32 10.3 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_2 PF00890.19 KFX98756.1 - 0.17 10.6 1.1 0.35 9.6 0.8 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 KFX98756.1 - 0.18 11.2 1.9 13 5.1 0.5 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX98756.1 - 0.22 11.1 1.6 0.24 11.0 0.3 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KFX98756.1 - 0.29 10.6 1.9 19 4.7 0.3 3.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.8 KFX98757.1 - 1.1e-48 165.5 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX98757.1 - 7.5e-05 21.6 0.1 0.00016 20.5 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KFX98757.1 - 0.0062 16.4 1.3 0.0094 15.8 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PsbU PF06514.6 KFX98757.1 - 0.11 12.2 0.1 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) MFS_1 PF07690.11 KFX98758.1 - 4.9e-33 114.2 42.1 3.8e-29 101.5 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KFX98758.1 - 0.034 14.1 5.0 3.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF3792 PF12670.2 KFX98758.1 - 6.7 6.6 12.3 0.78 9.6 1.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) ADH_zinc_N PF00107.21 KFX98760.1 - 7.5e-12 44.9 0.1 2e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX98760.1 - 6.5e-05 22.6 0.0 0.0032 17.2 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DUF1100 PF06500.6 KFX98761.1 - 3.5e-10 39.0 0.0 1.1e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KFX98761.1 - 1.2e-09 38.0 0.0 5.5e-09 35.9 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX98761.1 - 1.5e-08 34.7 0.2 7.6e-08 32.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX98761.1 - 2e-06 27.1 0.0 6.6e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KFX98761.1 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PAF-AH_p_II PF03403.8 KFX98761.1 - 0.065 11.5 0.0 0.22 9.7 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II ChW PF07538.6 KFX98761.1 - 0.35 10.4 1.9 0.81 9.2 1.3 1.6 1 0 0 1 1 1 0 Clostridial hydrophobic W Zn_clus PF00172.13 KFX98762.1 - 1.1e-06 28.4 5.5 2e-06 27.6 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX98763.1 - 8.8e-16 58.2 1.8 1.8e-14 53.9 1.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX98763.1 - 1.4e-05 24.8 0.4 9.3e-05 22.1 0.4 2.0 2 0 0 2 2 2 1 KR domain DUF1656 PF07869.7 KFX98764.1 - 0.23 11.2 1.3 0.48 10.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) 2OG-FeII_Oxy PF03171.15 KFX98765.1 - 0.016 15.5 0.0 0.048 13.9 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 KFX98766.1 - 2.2e-56 190.3 0.1 3.1e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KFX98766.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Fascin domain DUF3395 PF11875.3 KFX98767.1 - 9.4e-26 90.2 0.1 1.9e-25 89.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KFX98767.1 - 2e-14 53.0 0.6 5.6e-14 51.6 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KFX98768.1 - 1.3e-12 47.1 0.0 2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98768.1 - 1.2e-09 37.8 11.1 2.1e-09 37.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KFX98768.1 - 5.9 7.1 13.1 25 5.1 9.1 2.0 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region NAD_binding_1 PF00175.16 KFX98769.1 - 2e-28 99.0 0.0 3.8e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFX98769.1 - 4.6e-21 74.7 0.0 9e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFX98769.1 - 1.3e-09 38.1 0.0 6e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFX98769.1 - 0.00012 22.0 0.0 0.00035 20.5 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DUF4366 PF14283.1 KFX98769.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TEA PF01285.13 KFX98770.1 - 1.1e-13 51.1 1.2 1.1e-13 51.1 0.8 2.9 2 1 1 3 3 3 1 TEA/ATTS domain family RRM_1 PF00076.17 KFX98771.1 - 1.3e-75 248.9 1.0 5.6e-18 64.3 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX98771.1 - 1.2e-63 210.9 0.4 3.1e-13 49.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX98771.1 - 1.1e-36 124.3 0.0 4.7e-09 35.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFX98771.1 - 1.7e-06 27.7 1.0 0.18 11.5 0.0 4.9 5 1 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 KFX98771.1 - 3.5e-06 26.6 0.0 0.78 9.5 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFX98771.1 - 0.00016 21.4 1.6 3.4 7.5 0.0 4.1 4 0 0 4 4 4 2 RNA binding motif DUF1330 PF07045.6 KFX98771.1 - 0.2 11.5 2.9 1.3 8.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1330) Dynein_light PF01221.13 KFX98772.1 - 1.6e-41 140.1 1.7 2e-41 139.8 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 KFX98772.1 - 0.036 13.6 0.1 0.059 12.9 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 28 MYEOV2 PF15004.1 KFX98777.1 - 0.21 12.1 3.8 0.44 11.1 0.2 2.3 2 0 0 2 2 2 0 Myeloma-overexpressed-like AT_hook PF02178.14 KFX98777.1 - 0.42 10.4 3.9 0.88 9.4 2.7 1.6 1 0 0 1 1 1 0 AT hook motif Stm1_N PF09598.5 KFX98799.1 - 1.6e-12 47.9 5.8 1.6e-12 47.9 4.0 3.9 3 2 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.10 KFX98799.1 - 0.00099 19.5 4.0 0.00099 19.5 2.7 2.7 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family DOR PF14839.1 KFX98799.1 - 1.3 8.7 5.2 2 8.0 3.6 1.3 1 0 0 1 1 1 0 DOR family bZIP_1 PF00170.16 KFX98800.1 - 4.7e-06 26.4 6.1 4.7e-06 26.4 4.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor GvpL_GvpF PF06386.6 KFX98800.1 - 0.026 14.0 2.9 0.05 13.1 2.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 KFX98800.1 - 0.27 11.1 9.3 0.089 12.6 3.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 KFX98800.1 - 1.5 7.6 6.2 1.6 7.6 1.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.16 KFX98806.1 - 8.8e-52 175.6 0.0 1.1e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MR_MLE_C PF13378.1 KFX98807.1 - 8.8e-19 67.5 0.0 1.6e-17 63.4 0.0 2.4 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFX98807.1 - 8.4e-13 48.6 0.2 6.5e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 KFX98807.1 - 5.7e-05 22.1 0.0 9.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.11 KFX98807.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 KFX98808.1 - 1.5e-33 115.8 1.8 1.5e-33 115.8 1.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98808.1 - 1.8e-06 27.7 6.4 3.7e-06 26.7 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX98809.1 - 9.6e-110 367.2 28.3 1.2e-109 366.9 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98809.1 - 8.2e-23 80.6 39.4 2.2e-19 69.4 6.0 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX98809.1 - 0.00048 18.4 0.9 0.00048 18.4 0.6 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTS_2-RNA PF01885.11 KFX98824.1 - 1.7e-37 128.5 0.0 1.9e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KFX98824.1 - 0.068 12.9 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 La domain PDCD2_C PF04194.8 KFX98827.1 - 7.4e-13 48.4 0.5 1.2e-12 47.6 0.3 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain F-box PF00646.28 KFX98829.1 - 0.019 14.6 0.4 0.056 13.1 0.3 1.8 1 0 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.14 KFX98830.1 - 1.3e-10 40.9 0.2 0.0025 16.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Bul1_N PF04425.7 KFX98830.1 - 7.9e-07 27.9 1.4 0.00081 18.0 1.0 2.3 1 1 0 1 1 1 1 Bul1 N terminus DAO PF01266.19 KFX98830.1 - 0.00081 18.3 0.1 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX98830.1 - 0.00086 19.2 0.1 0.0025 17.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Bul1_C PF04426.7 KFX98830.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Pyr_redox_2 PF07992.9 KFX98830.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX98830.1 - 0.14 12.6 0.1 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy_3 PF13640.1 KFX98831.1 - 1.6e-08 34.9 0.0 3.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFX98831.1 - 8.3e-05 22.1 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 KFX98835.1 - 5.5e-22 77.8 0.3 8.9e-22 77.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98835.1 - 0.00021 21.1 8.6 0.00044 20.0 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IER PF05760.7 KFX98837.1 - 0.0037 17.2 17.7 0.0053 16.7 12.3 1.2 1 0 0 1 1 1 1 Immediate early response protein (IER) KilA-N PF04383.8 KFX98837.1 - 0.0039 16.7 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain APH PF01636.18 KFX98840.1 - 3e-15 56.5 0.0 5.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX98840.1 - 0.0022 17.6 0.1 0.006 16.1 0.0 1.7 2 1 0 2 2 2 1 Choline/ethanolamine kinase FAD_binding_4 PF01565.18 KFX98841.1 - 5.4e-17 61.5 2.5 1.2e-16 60.3 1.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX98841.1 - 1.5e-06 27.9 0.0 4.7e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like AIG2 PF06094.7 KFX98843.1 - 8.9e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Kp4 PF09044.5 KFX98844.1 - 3.4e-45 152.9 16.1 4.6e-23 81.4 1.6 2.0 2 0 0 2 2 2 2 Kp4 MU117 PF15474.1 KFX98844.1 - 0.028 14.8 11.4 0.18 12.2 2.0 2.6 2 1 0 2 2 2 0 Meiotically up-regulated gene family FYVE PF01363.16 KFX98844.1 - 0.051 13.4 0.2 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger Beta-TrCP_D PF12125.3 KFX98844.1 - 0.093 12.3 0.1 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP MLANA PF14991.1 KFX98844.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A zf-ribbon_3 PF13248.1 KFX98844.1 - 0.84 8.9 4.6 5.5 6.3 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M28 PF04389.12 KFX98845.1 - 1.5e-33 115.9 0.0 2.8e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFX98845.1 - 5.4e-16 58.1 0.0 1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 PA domain TFIIE_alpha PF02002.12 KFX98852.1 - 6e-17 61.0 0.2 1.1e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit SURF2 PF05477.6 KFX98852.1 - 0.25 10.4 2.6 0.41 9.7 1.8 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PseudoU_synth_1 PF01416.15 KFX98853.1 - 1.6e-21 76.6 0.0 4.1e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase ESCRT-II PF05871.7 KFX98853.1 - 0.1 12.5 1.3 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 ESCRT-II complex subunit Pkinase PF00069.20 KFX98854.1 - 8.8e-58 195.4 0.0 3.6e-43 147.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98854.1 - 2.2e-28 99.0 0.0 5.1e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX98854.1 - 6.3e-07 28.6 0.0 1.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KFX98854.1 - 0.11 12.2 0.0 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family SUA5 PF03481.8 KFX98854.1 - 0.23 11.5 1.8 0.66 10.0 1.1 1.8 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding Med22 PF06179.7 KFX98855.1 - 4.6e-17 62.0 0.1 6.6e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Cofilin_ADF PF00241.15 KFX98856.1 - 6e-24 84.3 0.0 4.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 KFX98857.1 - 5.2e-68 224.8 4.2 8.8e-22 76.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHFR_1 PF00186.14 KFX98858.1 - 6.6e-32 110.3 0.0 6.2e-25 87.6 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase RibD_C PF01872.12 KFX98858.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 RibD C-terminal domain Rotamase PF00639.16 KFX98859.1 - 3e-21 75.9 0.0 4.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KFX98859.1 - 1.4e-15 57.5 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KFX98859.1 - 2.2e-08 33.8 0.3 2.2e-08 33.8 0.2 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KFX98859.1 - 0.00017 22.2 0.0 0.00026 21.6 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain MbtH PF03621.8 KFX98859.1 - 0.1 11.9 0.4 7.8 5.9 0.0 2.6 3 0 0 3 3 3 0 MbtH-like protein RNA_POL_M_15KD PF02150.11 KFX98860.1 - 5.6e-14 51.5 3.0 5.6e-14 51.5 2.1 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KFX98860.1 - 4.6e-12 45.3 1.1 4.6e-12 45.3 0.7 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 KFX98860.1 - 0.0012 18.6 6.3 0.041 13.7 1.9 2.3 2 0 0 2 2 2 1 Double zinc ribbon GFA PF04828.9 KFX98860.1 - 0.021 14.7 6.0 0.35 10.8 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.2 KFX98860.1 - 0.036 13.8 3.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2981 PF11200.3 KFX98860.1 - 0.047 12.7 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Lar_restr_allev PF14354.1 KFX98860.1 - 0.091 13.0 2.6 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF3716 PF12511.3 KFX98860.1 - 0.43 10.2 7.5 2 8.0 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) zf-ribbon_3 PF13248.1 KFX98860.1 - 0.95 8.7 5.6 6.1 6.1 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KFX98860.1 - 1.6 8.5 6.9 2.4 7.9 2.5 2.6 2 1 0 2 2 2 0 Nudix N-terminal Zn_Tnp_IS91 PF14319.1 KFX98860.1 - 2.1 7.8 10.8 5 6.6 0.2 2.6 2 1 0 2 2 2 0 Transposase zinc-binding domain DUF2387 PF09526.5 KFX98860.1 - 2.1 8.3 6.1 1.9 8.4 0.1 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) VP_N-CPKC PF11475.3 KFX98860.1 - 2.5 7.7 5.7 23 4.6 1.0 2.6 2 0 0 2 2 2 0 Virion protein N terminal domain DUF2296 PF10058.4 KFX98860.1 - 2.7 7.8 7.2 0.62 9.8 0.7 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-B_box PF00643.19 KFX98860.1 - 3.6 7.5 9.2 24 4.8 0.1 3.1 2 1 1 3 3 3 0 B-box zinc finger HypA PF01155.14 KFX98860.1 - 4.8 6.9 6.9 36 4.1 4.8 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 KFX98860.1 - 5.2 7.3 7.4 1.4e+02 2.7 5.2 2.4 1 1 0 1 1 1 0 CHY zinc finger C1_4 PF07975.7 KFX98860.1 - 5.9 6.9 9.6 1.3 9.0 1.8 2.5 2 1 1 3 3 3 0 TFIIH C1-like domain Opy2 PF09463.5 KFX98860.1 - 7 6.8 7.8 2.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Opy2 protein zf-IS66 PF13005.2 KFX98860.1 - 7.5 6.6 6.9 5.5 7.0 0.2 2.8 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Ribosomal_L14 PF00238.14 KFX98861.1 - 3.7e-45 152.6 0.8 4.2e-45 152.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 KFX98862.1 - 2.4e-09 37.7 0.6 4e-08 33.7 0.1 2.9 2 1 0 2 2 2 1 SET domain BTB PF00651.26 KFX98863.1 - 8.8e-05 22.4 0.0 0.00036 20.4 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain Anillin PF08174.6 KFX98864.1 - 5.6e-32 110.6 0.5 1.8e-31 109.0 0.3 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFX98864.1 - 3.3e-09 36.8 0.0 1.3e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 PH domain RNase_P_pop3 PF08228.6 KFX98865.1 - 2.4e-06 27.4 0.0 4.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 GATase PF00117.23 KFX98866.1 - 2.5e-38 131.4 0.0 6.9e-38 130.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KFX98866.1 - 1.1e-34 118.0 0.0 1.9e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KFX98866.1 - 3.6e-12 45.7 0.0 2.5e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KFX98866.1 - 1.3e-07 31.3 0.0 3.3e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 KFX98866.1 - 0.0016 17.9 0.1 0.0041 16.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 KFX98866.1 - 0.0063 15.1 0.1 0.017 13.6 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 KFX98866.1 - 0.0076 15.7 0.2 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.8 KFX98866.1 - 0.022 14.0 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 KFX98866.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 KFX98866.1 - 0.14 11.6 0.1 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PP-loop family UCH PF00443.24 KFX98867.1 - 1.3e-43 149.0 0.7 2.7e-43 148.0 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KFX98867.1 - 3.7e-43 147.3 0.0 6e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 KFX98867.1 - 3.7e-15 56.1 0.4 8.6e-15 54.9 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Clathrin PF00637.15 KFX98868.1 - 0.016 14.8 0.1 0.07 12.7 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS UPF0220 PF05255.6 KFX98869.1 - 0.073 12.3 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) COX7a PF02238.10 KFX98869.1 - 0.19 11.4 2.2 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Clathrin_lg_ch PF01086.12 KFX98870.1 - 3.1e-68 230.0 8.1 3.7e-68 229.8 5.6 1.0 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.8 KFX98871.1 - 2.8e-21 75.5 0.3 5.3e-21 74.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 KFX98871.1 - 0.001 18.5 0.1 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) CTK3 PF12243.3 KFX98871.1 - 0.013 15.1 0.2 0.032 13.8 0.2 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 LepA_C PF06421.7 KFX98871.1 - 0.028 14.3 0.5 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus CDC37_N PF03234.9 KFX98872.1 - 7.4e-55 185.9 7.0 7.4e-55 185.9 4.8 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KFX98872.1 - 8.8e-44 149.0 0.4 2.5e-43 147.5 0.0 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KFX98872.1 - 2.2e-25 88.3 1.7 2.2e-25 88.3 1.2 2.6 2 1 1 3 3 3 1 Cdc37 C terminal domain HTH_22 PF13309.1 KFX98872.1 - 0.12 12.1 0.5 3.2 7.5 0.0 3.2 3 1 0 3 3 3 0 HTH domain Seryl_tRNA_N PF02403.17 KFX98872.1 - 2.1 8.3 9.1 0.26 11.3 0.5 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ABC_membrane PF00664.18 KFX98873.1 - 2.2e-45 155.2 11.5 3.1e-45 154.7 8.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFX98873.1 - 1.4e-32 112.8 0.0 3.4e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Glyco_hydro_16 PF00722.16 KFX98873.1 - 6.2e-10 38.6 0.2 2.1e-09 36.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 AAA_21 PF13304.1 KFX98873.1 - 0.0008 19.4 0.4 1.4 8.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFX98873.1 - 0.0014 17.9 0.0 0.0065 15.7 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX98873.1 - 0.0098 15.4 0.2 0.023 14.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX98873.1 - 0.015 15.3 1.8 0.033 14.1 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KFX98873.1 - 0.054 13.8 0.1 1.3 9.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX98873.1 - 0.055 14.2 0.0 0.18 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KFX98873.1 - 0.087 12.7 0.6 0.55 10.1 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KFX98873.1 - 0.096 12.8 0.5 0.68 10.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain Nitroreductase PF00881.19 KFX98874.1 - 6.5e-16 58.5 0.0 7.7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Cmyb_C PF09316.5 KFX98874.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 C-myb, C-terminal DUF3510 PF12022.3 KFX98874.1 - 0.074 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) PsbY PF06298.6 KFX98874.1 - 0.41 10.1 1.9 0.92 9.0 1.3 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) UBA_4 PF14555.1 KFX98876.1 - 1.5e-13 49.9 1.8 2.1e-13 49.5 1.2 1.2 1 0 0 1 1 1 1 UBA-like domain TOM13 PF08219.6 KFX98877.1 - 1.6e-28 98.2 0.0 2.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF3449 PF11931.3 KFX98878.1 - 2.7e-68 229.3 0.0 3.1e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) DUF951 PF06107.6 KFX98878.1 - 0.016 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Kinesin PF00225.18 KFX98882.1 - 2.5e-13 49.4 0.0 3.3e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Ish1 PF10281.4 KFX98883.1 - 6.1e-80 262.8 33.3 1.3e-14 53.9 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KFX98883.1 - 1.7e-13 49.8 0.6 0.0018 17.7 0.0 6.5 7 0 0 7 7 7 4 HeH/LEM domain SAP PF02037.22 KFX98883.1 - 1.4e-10 40.4 0.0 0.96 9.0 0.0 7.4 7 1 0 7 7 7 3 SAP domain Slx4 PF09494.5 KFX98883.1 - 2.8e-06 26.9 1.8 3.1 7.5 0.0 6.2 6 0 0 6 6 6 2 Slx4 endonuclease APC2 PF08672.6 KFX98883.1 - 0.00077 19.6 1.6 20 5.5 0.0 5.7 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 SAP30_Sin3_bdg PF13867.1 KFX98883.1 - 0.0019 18.0 1.8 1.8 8.4 0.0 3.9 4 0 0 4 4 4 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Thioredoxin_6 PF13848.1 KFX98883.1 - 0.0086 15.8 0.2 0.32 10.7 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like domain SAM_2 PF07647.12 KFX98883.1 - 0.011 15.5 2.4 6.9 6.5 0.0 3.8 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Peptidase_C39_2 PF13529.1 KFX98883.1 - 6.6 7.0 10.6 2.2 8.6 1.2 3.7 3 0 0 3 3 3 0 Peptidase_C39 like family CoA_transf_3 PF02515.12 KFX98884.1 - 6.6e-57 191.8 0.2 1.5e-56 190.6 0.2 1.6 1 0 0 1 1 1 1 CoA-transferase family III p450 PF00067.17 KFX98884.1 - 1.9e-51 175.0 0.0 3.1e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFX98893.1 - 4.6e-58 196.8 0.0 6.3e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRASP55_65 PF04495.9 KFX98893.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain zf-C2H2 PF00096.21 KFX98905.1 - 1.7e-12 46.9 9.4 1.8e-06 27.9 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX98905.1 - 3.8e-09 36.2 8.9 0.00031 20.8 1.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX98905.1 - 1.3e-08 34.7 2.2 1.3e-08 34.7 1.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFX98905.1 - 5e-05 23.0 0.1 5e-05 23.0 0.1 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX98905.1 - 0.0029 17.7 0.3 0.49 10.6 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX98905.1 - 0.017 15.3 0.9 0.46 10.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFX98905.1 - 0.037 14.1 2.1 0.084 13.0 1.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Tmemb_cc2 PF10267.4 KFX98905.1 - 1.9 6.9 8.2 9.2 4.7 2.7 2.1 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Choline_kinase PF01633.15 KFX98927.1 - 3.5e-60 203.1 0.0 1.3e-59 201.2 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KFX98927.1 - 4.8e-22 77.1 0.0 1.1e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KFX98927.1 - 1.4e-08 34.7 1.0 1.9e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mem_trans PF03547.13 KFX98928.1 - 2.3e-51 174.2 0.0 3.9e-51 173.5 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.20 KFX98929.1 - 3e-48 164.2 0.0 6.2e-45 153.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98929.1 - 1.5e-31 109.4 0.0 2.9e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX98929.1 - 0.00026 20.0 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFX98929.1 - 0.0038 16.1 0.1 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KFX98929.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DNA_methylase PF00145.12 KFX98930.1 - 1.1e-16 60.8 0.1 2.7e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 KFX98930.1 - 0.0013 18.7 0.1 0.0062 16.5 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 KFX98930.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Hpt PF01627.18 KFX98931.1 - 3.5e-14 52.5 0.1 4.5e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Hpt domain Carb_anhydrase PF00194.16 KFX98931.1 - 0.072 12.0 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase WXG100 PF06013.7 KFX98931.1 - 0.095 12.7 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Sigma70_ner PF04546.8 KFX98931.1 - 0.48 10.0 3.9 3.3 7.2 2.7 1.9 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF2838 PF10998.3 KFX98933.1 - 1.8e-47 159.7 8.4 1.8e-47 159.7 5.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1640 PF07798.6 KFX98933.1 - 0.5 10.3 1.9 0.34 10.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Not3 PF04065.10 KFX98933.1 - 1.9 7.7 5.5 0.32 10.2 1.3 1.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Val_tRNA-synt_C PF10458.4 KFX98933.1 - 4.4 7.4 6.8 25 5.0 2.8 2.5 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SMC_N PF02463.14 KFX98934.1 - 1.5e-58 197.5 6.2 6.5e-57 192.2 4.3 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX98934.1 - 4.4e-26 91.2 0.0 2.7e-25 88.6 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KFX98934.1 - 6.7e-10 39.6 22.3 6.7e-10 39.6 15.5 6.0 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX98934.1 - 1.4e-09 38.3 0.7 1.8e-05 24.8 0.0 3.9 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KFX98934.1 - 3.1e-08 33.0 0.0 6.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFX98934.1 - 6.1e-06 25.6 28.6 0.013 14.7 3.6 4.5 3 1 1 4 4 4 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 KFX98934.1 - 0.0035 17.2 0.0 0.02 14.8 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 KFX98934.1 - 0.054 13.1 110.3 0.007 15.9 6.4 7.3 3 2 3 7 7 7 0 IncA protein DUF3584 PF12128.3 KFX98934.1 - 1.1 6.5 98.2 0.13 9.6 2.7 4.5 3 1 0 4 4 4 0 Protein of unknown function (DUF3584) WD40 PF00400.27 KFX98935.1 - 3.5e-34 115.4 6.3 6e-07 29.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX98935.1 - 1.8e-07 31.0 0.0 0.0092 15.7 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF3425 PF11905.3 KFX98935.1 - 0.052 13.4 0.2 0.28 11.0 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) Arf PF00025.16 KFX98936.1 - 4.9e-64 214.7 0.0 8.4e-64 213.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3336 PF11815.3 KFX98936.1 - 4.3e-51 172.2 4.9 7.3e-51 171.5 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFX98936.1 - 3.1e-19 69.7 0.2 7.5e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase G-alpha PF00503.15 KFX98936.1 - 5.1e-10 38.6 0.0 3.3e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFX98936.1 - 8e-08 31.7 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFX98936.1 - 5.4e-07 30.1 0.0 1.4e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX98936.1 - 3.3e-06 27.0 0.0 7.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KFX98936.1 - 6e-06 25.7 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFX98936.1 - 6.1e-05 22.2 0.0 9.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX98936.1 - 0.099 12.0 0.0 1.3 8.4 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF876 PF05936.7 KFX98936.1 - 0.12 10.8 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) DUF2347 PF09804.4 KFX98937.1 - 3.1e-100 335.0 0.0 3.9e-100 334.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KFX98937.1 - 3.7e-43 147.6 0.0 7.1e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KFX98937.1 - 5.4e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFX98937.1 - 0.0013 17.3 0.0 0.027 12.9 0.0 2.3 2 1 0 3 3 3 1 Transport protein Avl9 Fork_head PF00250.13 KFX98944.1 - 2.8e-23 81.7 0.5 1.9e-22 79.1 0.1 2.4 3 0 0 3 3 3 1 Fork head domain FHA PF00498.21 KFX98944.1 - 1.3e-09 38.0 0.1 4.8e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 FHA domain CENP-H PF05837.7 KFX98959.1 - 1.9e-27 95.5 5.2 1.7e-24 85.9 0.8 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) Adhes-Ig_like PF09085.5 KFX98959.1 - 0.031 14.1 0.6 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like TSC22 PF01166.13 KFX98959.1 - 0.038 13.9 0.8 4 7.4 0.3 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4482 PF14818.1 KFX98959.1 - 0.082 13.5 4.2 2.6 8.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) DUF972 PF06156.8 KFX98959.1 - 0.58 10.5 5.5 12 6.2 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) SET PF00856.23 KFX98960.1 - 1.8e-21 77.1 0.1 1.1e-20 74.5 0.0 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 KFX98960.1 - 1.6e-17 63.6 5.7 1.6e-17 63.6 4.0 2.1 2 0 0 2 2 2 1 Pre-SET motif Nop52 PF05997.7 KFX98961.1 - 8.6e-56 188.7 0.0 9.9e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 KFX98961.1 - 0.036 13.8 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DAGK_cat PF00781.19 KFX98962.1 - 1.7e-23 82.4 0.0 2.8e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 KFX98963.1 - 1.3e-96 324.0 9.2 2.3e-96 323.1 6.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KFX98963.1 - 3.1e-63 211.6 1.8 6.4e-63 210.6 1.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KFX98963.1 - 8.4e-63 209.8 0.0 2.7e-62 208.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KFX98963.1 - 2.6e-11 43.6 7.9 1.3e-06 28.5 0.1 4.2 1 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KFX98963.1 - 0.00029 20.7 10.4 0.0089 15.8 0.0 3.9 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFX98963.1 - 0.00065 19.5 1.9 0.45 10.7 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 KFX98963.1 - 0.022 15.2 5.3 0.25 11.8 0.0 4.4 5 1 1 6 6 6 0 HEAT-like repeat Mago_nashi PF02792.9 KFX98964.1 - 2.6e-74 247.6 0.2 3e-74 247.4 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Ion_trans PF00520.26 KFX98965.1 - 1.1e-93 312.0 90.7 8.3e-31 106.7 7.8 6.2 6 1 0 6 6 6 4 Ion transport protein EF-hand_1 PF00036.27 KFX98965.1 - 4e-05 22.6 0.0 0.00012 21.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX98965.1 - 0.0008 19.0 0.0 0.0032 17.2 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KFX98965.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair PKD_channel PF08016.7 KFX98965.1 - 8.1 4.7 61.4 0.0052 15.2 5.8 6.6 6 1 1 7 7 7 0 Polycystin cation channel ADH_zinc_N_2 PF13602.1 KFX98966.1 - 6.3e-21 75.5 0.0 1.2e-20 74.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX98966.1 - 4.9e-12 45.5 0.0 8.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2173 PF09941.4 KFX98966.1 - 0.036 13.9 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Cupin_2 PF07883.6 KFX98967.1 - 5.7e-10 38.5 0.0 9.4e-10 37.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 KFX98967.1 - 0.00085 18.5 0.0 0.0017 17.5 0.0 1.5 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF4089 PF13318.1 KFX98967.1 - 0.05 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) DUF1637 PF07847.7 KFX98967.1 - 0.066 12.5 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) AAA_33 PF13671.1 KFX98968.1 - 5.2e-15 55.5 0.0 3.5e-13 49.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain RNA_ligase PF09414.5 KFX98968.1 - 1e-08 35.2 0.1 1.8e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 RNA ligase Y_phosphatase PF00102.22 KFX98968.1 - 3e-05 23.4 0.0 0.00012 21.4 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFX98968.1 - 3.3e-05 24.1 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_22 PF13401.1 KFX98968.1 - 0.0016 18.5 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Y_phosphatase2 PF03162.8 KFX98968.1 - 0.0063 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_17 PF13207.1 KFX98968.1 - 0.047 14.5 0.0 0.19 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFX98968.1 - 0.048 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DSPc PF00782.15 KFX98968.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain AAA PF00004.24 KFX98968.1 - 0.096 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TauD PF02668.11 KFX98969.1 - 1.4e-51 175.6 0.6 1.6e-51 175.4 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Acetyltransf_1 PF00583.19 KFX98970.1 - 3.9e-05 23.5 0.0 7.5e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX98970.1 - 5.9e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX98970.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Fungal_trans PF04082.13 KFX98971.1 - 4.1e-13 48.7 0.0 5.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98971.1 - 1e-09 38.0 6.9 2.1e-09 37.1 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX98972.1 - 1.5e-30 106.3 3.2 2.1e-30 105.8 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX98972.1 - 3.1e-17 62.8 0.3 3.7e-17 62.5 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX98972.1 - 2.1e-15 57.1 0.2 2.8e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX98972.1 - 1.1e-07 31.5 0.6 1.9e-07 30.7 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX98972.1 - 3.4e-05 22.8 0.0 5.9e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFX98972.1 - 0.00017 21.7 0.3 0.00027 21.0 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PA PF02225.17 KFX98972.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 PA domain Eno-Rase_NADH_b PF12242.3 KFX98972.1 - 0.083 12.6 0.6 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MinC_C PF03775.11 KFX98972.1 - 0.085 12.4 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain HEAT_2 PF13646.1 KFX98973.1 - 0.0014 18.8 4.2 5.7 7.2 0.0 5.1 5 0 0 5 5 5 3 HEAT repeats NAD_binding_10 PF13460.1 KFX98976.1 - 2.2e-06 27.8 0.1 2.9e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KFX98976.1 - 0.0069 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KFX98976.1 - 0.039 12.6 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX98976.1 - 0.061 12.2 0.0 2.5 6.9 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein Glyco_hydro_35 PF01301.14 KFX98977.1 - 9e-94 314.3 0.1 1.1e-93 314.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KFX98977.1 - 2.5e-11 43.3 0.2 9.4e-11 41.4 0.1 1.8 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 KFX98977.1 - 1.9e-07 31.3 0.0 0.00072 19.8 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain MIP PF00230.15 KFX98979.1 - 7.8e-25 87.6 11.5 1.6e-24 86.6 7.9 1.5 1 1 0 1 1 1 1 Major intrinsic protein Ephrin_lbd PF01404.14 KFX98979.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain Lactonase PF10282.4 KFX98980.1 - 9.7e-85 284.6 0.0 1.2e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_76 PF03663.9 KFX98982.1 - 8.7e-37 127.3 17.7 1.1e-36 126.9 12.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFX98982.1 - 0.00056 19.0 0.2 0.72 8.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 KFX98983.1 - 8.4e-12 44.5 0.0 1.3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98983.1 - 8.2e-08 32.0 9.4 1.3e-07 31.3 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KFX98984.1 - 1.1e-10 41.1 0.4 1.3e-10 40.9 0.0 1.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KFX98984.1 - 2.6e-06 26.6 3.6 8.5e-06 24.9 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX98984.1 - 5.9e-06 26.6 0.0 3.7e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX98984.1 - 0.00019 21.3 0.0 0.00047 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX98984.1 - 0.0013 18.6 0.2 0.0045 16.8 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX98984.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KFX98984.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Bac_rhamnosid PF05592.6 KFX98985.1 - 1.8e-22 79.2 0.1 2.5e-17 62.3 0.0 2.5 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFX98985.1 - 5.1e-08 32.0 1.8 8.9e-08 31.2 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 KFX98985.1 - 0.00036 19.3 0.0 0.00052 18.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase ChAPs PF09295.5 KFX98986.1 - 8.3e-157 521.9 0.0 1e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 KFX98986.1 - 4.4e-07 29.9 0.5 0.63 10.8 0.0 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX98986.1 - 0.00013 21.5 0.1 0.95 9.1 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 KFX98986.1 - 0.00027 21.1 0.0 0.15 12.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98986.1 - 0.00056 19.6 0.6 4.5 7.4 0.7 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX98986.1 - 0.0098 15.6 0.8 0.25 11.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX98986.1 - 0.042 13.6 2.2 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98986.1 - 0.085 12.6 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_gE PF02480.11 KFX98987.1 - 0.00077 17.8 0.4 0.0014 16.9 0.3 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 KFX98987.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family CcmD PF04995.9 KFX98987.1 - 0.15 11.8 0.9 0.31 10.7 0.6 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ORC6 PF05460.8 KFX98987.1 - 1 8.4 7.6 1.4 7.9 5.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_3 PF07859.8 KFX98988.1 - 2.3e-39 135.1 0.0 2.5e-38 131.7 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX98988.1 - 0.0023 16.6 0.1 0.018 13.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Transferase PF02458.10 KFX98989.1 - 1.3e-26 93.0 0.0 3.3e-25 88.4 0.0 2.0 2 0 0 2 2 2 2 Transferase family Dsh_C PF12316.3 KFX98989.1 - 0.071 13.2 0.4 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RHH_1 PF01402.16 KFX98989.1 - 0.16 11.9 0.3 5.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Cellulase PF00150.13 KFX98991.1 - 4.1e-41 141.0 6.8 4.2e-40 137.7 3.1 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 KFX98991.1 - 4e-24 84.2 5.2 4.1e-21 74.5 2.4 4.0 4 0 0 4 4 4 2 Carbohydrate binding domain X2 TPR_11 PF13414.1 KFX98992.1 - 5.3e-12 45.1 4.6 0.0022 17.6 0.0 5.2 5 0 0 5 5 5 4 TPR repeat TPR_17 PF13431.1 KFX98992.1 - 1.1e-05 25.2 0.2 0.027 14.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98992.1 - 0.0048 17.5 7.9 3.4 8.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98992.1 - 0.013 16.0 13.2 15 6.5 0.9 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX98992.1 - 0.015 15.6 5.7 4.7 7.6 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX98992.1 - 1.4 8.6 11.3 6.1 6.6 0.5 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat BTB PF00651.26 KFX99007.1 - 8.1e-11 41.8 0.0 2.6e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_92 PF07971.7 KFX99007.1 - 0.0073 15.0 0.0 0.0093 14.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Phage_tail_L PF05100.7 KFX99007.1 - 0.044 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Phage minor tail protein L T2SK PF03934.8 KFX99007.1 - 0.097 11.8 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K Vps51 PF08700.6 KFX99008.1 - 1.9e-10 40.4 0.0 9.5e-10 38.1 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 G-alpha PF00503.15 KFX99016.1 - 1.9e-119 398.8 0.5 2.4e-119 398.5 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFX99016.1 - 5.8e-14 51.7 1.0 3.2e-09 36.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX99016.1 - 0.00029 20.0 2.3 0.021 13.9 0.1 2.8 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KFX99016.1 - 0.0091 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KFX99016.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PALP PF00291.20 KFX99019.1 - 2.8e-22 79.3 0.2 3.3e-22 79.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rep_fac-A_C PF08646.5 KFX99020.1 - 3.8e-58 195.3 4.6 8e-55 184.5 0.5 3.2 2 1 1 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KFX99020.1 - 3.9e-22 77.9 0.0 8.5e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KFX99020.1 - 8.9e-21 73.5 0.5 3.5e-08 33.1 0.0 5.3 4 2 2 6 6 6 3 OB-fold nucleic acid binding domain DUF223 PF02721.9 KFX99020.1 - 0.0047 16.9 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF223 Gloverin PF10793.4 KFX99020.1 - 0.035 13.7 0.4 7.8 6.1 0.0 2.4 1 1 1 2 2 2 0 Gloverin-like protein VD10_N PF08476.5 KFX99020.1 - 0.075 12.5 0.0 21 4.6 0.0 2.7 2 0 0 2 2 2 0 Viral D10 N-terminal PCI PF01399.22 KFX99021.1 - 0.0003 21.0 0.0 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.1 KFX99021.1 - 0.0022 17.6 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX99021.1 - 0.024 15.2 0.5 1.2 9.9 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX99021.1 - 0.07 13.2 0.3 6.3 7.0 0.2 2.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Aldedh PF00171.17 KFX99022.1 - 1.8e-08 33.1 8.3 5.4e-06 25.0 3.9 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF3535 PF12054.3 KFX99024.1 - 8.1e-144 479.5 4.7 3.9e-143 477.2 2.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KFX99024.1 - 2e-72 243.5 0.0 3e-72 242.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KFX99024.1 - 3.4e-18 64.0 10.6 0.051 13.6 0.0 10.3 9 0 0 9 9 9 6 HEAT repeat Helicase_C PF00271.26 KFX99024.1 - 4.3e-15 55.3 0.0 9.1e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KFX99024.1 - 1.2e-07 31.9 0.2 0.23 11.8 0.0 4.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KFX99024.1 - 5.5e-05 22.6 0.0 0.069 12.4 0.0 3.5 2 1 2 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 KFX99024.1 - 0.0026 18.2 16.2 30 5.2 0.0 9.2 9 0 0 9 9 9 0 HEAT-like repeat Nop10p PF04135.7 KFX99031.1 - 4.1e-19 68.0 0.1 6.5e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family zf-RAG1 PF10426.4 KFX99031.1 - 0.66 9.9 2.3 3.7 7.5 0.3 2.3 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Mito_carr PF00153.22 KFX99032.1 - 4.3e-15 55.1 0.8 0.015 14.9 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.22 KFX99033.1 - 5.1e-13 48.5 1.1 7.6e-13 48.0 0.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.7 KFX99034.1 - 6.6e-36 123.2 11.8 6.6e-36 123.2 8.2 1.9 2 0 0 2 2 2 1 Rrp15p FliL PF03748.9 KFX99034.1 - 0.41 10.6 5.6 2.6 8.0 0.3 2.6 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL Daxx PF03344.10 KFX99034.1 - 2.6 6.4 20.6 3.3 6.0 14.3 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_S64 PF08192.6 KFX99034.1 - 6 5.0 13.0 7.3 4.7 9.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 SRP54 PF00448.17 KFX99035.1 - 2e-76 255.8 1.9 2.6e-76 255.4 0.9 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KFX99035.1 - 7.1e-25 87.2 4.4 7.1e-25 87.2 3.0 4.3 4 2 2 6 6 4 1 Signal peptide binding domain SRP54_N PF02881.14 KFX99035.1 - 2.1e-16 59.7 1.3 4.8e-16 58.6 0.9 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KFX99035.1 - 1.2e-08 34.6 0.1 3.7e-08 33.0 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFX99035.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX99035.1 - 1.4e-05 25.9 0.0 3.7e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KFX99035.1 - 1.5e-05 24.7 0.1 5.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFX99035.1 - 4.2e-05 22.7 0.0 4.2e-05 22.7 0.0 1.9 2 0 0 2 2 1 1 Zeta toxin AAA_31 PF13614.1 KFX99035.1 - 0.00018 21.4 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KFX99035.1 - 0.00089 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KFX99035.1 - 0.0014 18.6 0.0 0.0035 17.3 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.18 KFX99035.1 - 0.0016 17.9 0.2 0.0061 15.9 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 KFX99035.1 - 0.0017 18.4 0.0 0.0054 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFX99035.1 - 0.0038 16.6 0.0 0.014 14.7 0.0 2.0 1 0 0 1 1 1 1 Thymidylate kinase SRPRB PF09439.5 KFX99035.1 - 0.0041 16.3 1.4 2.2 7.4 1.2 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KFX99035.1 - 0.0052 16.3 0.6 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KFX99035.1 - 0.0065 16.7 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX99035.1 - 0.023 14.9 0.2 0.062 13.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 KFX99035.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 KFX99035.1 - 0.03 14.2 0.2 0.065 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 KFX99035.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin TrwB_AAD_bind PF10412.4 KFX99035.1 - 0.035 12.7 0.0 0.074 11.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Glyco_hydro_45 PF02015.11 KFX99036.1 - 1.3e-55 188.5 7.3 1.6e-55 188.3 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Noc2 PF03715.8 KFX99038.1 - 4.1e-72 242.5 0.2 1.5e-71 240.7 0.0 2.0 2 0 0 2 2 2 1 Noc2p family DUF4477 PF14780.1 KFX99038.1 - 0.052 12.9 0.4 0.11 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Hid1 PF12722.2 KFX99038.1 - 0.85 7.2 5.8 1.1 6.8 4.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 KFX99038.1 - 1.3 7.4 20.7 1.9 6.8 14.4 1.2 1 0 0 1 1 1 0 Daxx Family VPS28 PF03997.7 KFX99039.1 - 8.4e-56 188.5 0.1 9.9e-56 188.3 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 KFX99039.1 - 0.013 15.3 2.5 2.5 7.9 0.2 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Zip PF02535.17 KFX99065.1 - 7.3e-47 159.9 2.6 9.8e-47 159.4 1.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Iron_permease PF04120.7 KFX99066.1 - 4.8e-40 136.2 15.2 6e-20 71.1 0.0 4.2 4 0 0 4 4 4 4 Low affinity iron permease Ank_2 PF12796.2 KFX99067.1 - 6.4e-74 244.3 14.5 2.6e-21 75.7 0.6 6.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX99067.1 - 7.1e-71 230.6 22.2 4.1e-09 35.7 0.0 12.5 12 1 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 KFX99067.1 - 1.4e-55 184.0 23.6 2.3e-13 49.8 0.3 9.5 1 1 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99067.1 - 4.7e-52 168.7 13.9 2.8e-05 23.9 0.0 12.4 13 1 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 KFX99067.1 - 5.9e-52 173.1 14.3 2.8e-13 49.9 0.0 9.3 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Cation_efflux PF01545.16 KFX99070.1 - 2.2e-71 240.2 6.8 2.8e-71 239.9 4.7 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 KFX99070.1 - 0.013 14.4 0.7 0.013 14.4 0.5 2.2 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component Cation_efflux PF01545.16 KFX99071.1 - 2.5e-71 240.0 0.5 2.5e-71 240.0 0.3 2.4 2 1 0 2 2 2 1 Cation efflux family Nramp PF01566.13 KFX99071.1 - 6.9e-59 199.4 7.9 3.4e-41 141.2 1.9 3.2 3 1 1 4 4 4 2 Natural resistance-associated macrophage protein GAGE PF05831.6 KFX99071.1 - 0.092 12.8 0.1 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 GAGE protein Usp PF00582.21 KFX99072.1 - 4.7e-07 30.0 0.0 7.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family E1-E2_ATPase PF00122.15 KFX99073.1 - 1.8e-42 144.9 7.4 1.8e-42 144.9 5.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX99073.1 - 4.6e-23 82.7 0.0 9.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX99073.1 - 7e-12 45.9 0.0 1.6e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX99073.1 - 6.5e-05 22.6 0.3 0.0088 15.6 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFX99073.1 - 0.00032 20.7 0.0 0.0008 19.5 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain His_biosynth PF00977.16 KFX99077.1 - 4e-31 108.0 0.0 4.8e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Chordopox_A13L PF05961.6 KFX99077.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein TPR_2 PF07719.12 KFX99078.1 - 3.2e-06 26.6 9.4 2.8 8.0 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX99078.1 - 8.6e-06 25.5 0.2 6.8 7.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX99078.1 - 4.9e-05 22.8 0.6 0.16 11.7 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX99078.1 - 0.0003 21.0 6.4 35 4.8 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFX99078.1 - 0.00046 19.7 3.7 2 8.1 0.2 4.9 5 0 0 5 5 5 1 TPR repeat TPR_1 PF00515.23 KFX99078.1 - 0.0012 18.3 0.9 52 3.6 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX99078.1 - 0.0017 18.8 19.5 19 6.2 0.3 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX99078.1 - 0.0081 16.8 18.4 0.23 12.1 0.1 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX99078.1 - 0.033 14.1 8.3 7.3 6.6 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat RIX1 PF08167.7 KFX99079.1 - 5.2e-48 162.8 0.1 1.1e-47 161.7 0.1 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MgtE_N PF03448.12 KFX99080.1 - 0.053 13.8 14.6 2.8e+03 -1.4 10.1 3.3 1 1 0 1 1 1 0 MgtE intracellular N domain CH PF00307.26 KFX99081.1 - 2.9e-38 130.2 0.1 7.4e-19 67.7 0.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFX99081.1 - 1.9e-25 88.5 0.1 6.3e-25 86.9 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFX99081.1 - 5.4e-13 48.4 0.0 5.2e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.1 KFX99081.1 - 0.00035 20.2 0.1 0.0036 17.0 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 KFX99081.1 - 0.00047 20.4 3.4 0.17 12.1 0.0 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.27 KFX99081.1 - 0.011 14.9 0.1 0.096 12.0 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 KFX99081.1 - 0.012 15.2 0.4 0.091 12.3 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain pair Rabaptin PF03528.10 KFX99081.1 - 0.025 14.5 0.1 0.46 10.4 0.0 2.9 2 1 0 2 2 2 0 Rabaptin EIAV_Rev PF11129.3 KFX99081.1 - 0.15 12.0 1.5 0.34 10.8 1.0 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus Polysacc_deac_1 PF01522.16 KFX99082.1 - 4.8e-33 113.4 0.0 7.2e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KFX99082.1 - 0.00026 20.9 14.1 0.00068 19.5 9.8 1.7 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 KFX99082.1 - 0.00069 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Gly-zipper_Omp PF13488.1 KFX99084.1 - 2.2 7.9 10.7 0.25 11.0 3.7 2.1 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 KFX99084.1 - 7.6 6.2 12.3 0.67 9.6 5.0 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain COX6B PF02297.12 KFX99085.1 - 1.3e-25 89.2 5.1 1.6e-25 88.9 3.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KFX99085.1 - 0.07 13.1 1.4 0.13 12.2 0.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.4 KFX99086.1 - 3.3e-50 169.8 12.2 3.8e-50 169.6 8.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network MutS_V PF00488.16 KFX99088.1 - 1.3e-96 322.5 0.1 2.1e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX99088.1 - 2.1e-35 122.3 1.2 4.9e-35 121.1 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KFX99088.1 - 2e-20 73.2 0.0 5.9e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 KFX99088.1 - 1.8e-18 66.5 0.5 7.3e-18 64.6 0.0 2.3 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.13 KFX99088.1 - 2e-16 59.9 2.1 7.2e-16 58.1 1.4 2.1 1 0 0 1 1 1 1 MutS family domain IV Peptidase_M16 PF00675.15 KFX99088.1 - 0.018 14.8 0.1 0.087 12.5 0.0 2.1 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) SCAN PF02023.12 KFX99088.1 - 0.047 13.1 2.0 0.067 12.6 0.5 1.9 2 0 0 2 2 2 0 SCAN domain AAA PF00004.24 KFX99089.1 - 2.8e-52 176.3 0.0 2.2e-43 147.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KFX99089.1 - 1e-27 95.9 0.2 2.6e-27 94.6 0.1 1.8 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KFX99089.1 - 9.1e-10 38.8 4.3 5.6e-05 23.2 0.2 3.8 2 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 KFX99089.1 - 2.7e-07 30.4 0.5 0.0024 17.5 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Zeta_toxin PF06414.7 KFX99089.1 - 2e-05 23.8 0.6 0.23 10.5 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin RuvB_N PF05496.7 KFX99089.1 - 2.1e-05 23.6 0.0 0.0081 15.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 KFX99089.1 - 2.3e-05 24.4 0.0 0.0048 16.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KFX99089.1 - 2.4e-05 25.1 0.0 0.14 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFX99089.1 - 3.4e-05 23.9 0.5 0.85 9.7 0.1 4.0 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFX99089.1 - 4.9e-05 22.8 0.4 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 KFX99089.1 - 5.5e-05 22.9 0.2 0.46 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX99089.1 - 0.00019 21.3 0.0 0.68 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFX99089.1 - 0.00027 21.2 0.1 0.19 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFX99089.1 - 0.00059 19.2 2.6 0.7 9.2 0.1 3.9 2 2 1 4 4 4 1 AAA domain AAA_19 PF13245.1 KFX99089.1 - 0.00062 19.4 0.1 1.2 8.9 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 KFX99089.1 - 0.0012 18.7 0.0 0.25 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFX99089.1 - 0.0023 18.0 0.0 3.4 7.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 KFX99089.1 - 0.0032 17.3 0.0 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KFX99089.1 - 0.0054 16.7 1.9 3.3 7.6 0.0 3.3 4 0 0 4 4 2 1 AAA domain ABC_tran PF00005.22 KFX99089.1 - 0.0058 16.9 0.1 3 8.1 0.1 2.9 2 0 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 KFX99089.1 - 0.0059 16.2 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KFX99089.1 - 0.0072 15.2 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KFX99089.1 - 0.0077 15.4 0.3 0.13 11.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SKI PF01202.17 KFX99089.1 - 0.0086 15.9 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Sigma54_activat PF00158.21 KFX99089.1 - 0.014 14.8 0.0 0.92 8.9 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain TIP49 PF06068.8 KFX99089.1 - 0.021 13.5 0.0 0.64 8.6 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus APS_kinase PF01583.15 KFX99089.1 - 0.087 12.4 0.2 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase Viral_helicase1 PF01443.13 KFX99089.1 - 0.099 12.1 0.0 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 KFX99089.1 - 0.13 11.2 0.4 2.3 7.1 0.0 2.5 2 1 1 3 3 2 0 KAP family P-loop domain Torsin PF06309.6 KFX99089.1 - 0.16 11.8 0.0 8.2 6.3 0.0 3.2 4 0 0 4 4 3 0 Torsin NB-ARC PF00931.17 KFX99089.1 - 0.23 10.2 0.2 5.2 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.18 KFX99090.1 - 5.3e-134 446.1 0.1 1.1e-133 445.2 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFX99090.1 - 1.2e-28 100.0 0.8 3.9e-28 98.3 0.5 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFX99090.1 - 9.4e-08 31.4 0.0 8.7e-06 25.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFX99090.1 - 4.6e-06 26.4 0.0 1.3e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RecX PF02631.11 KFX99090.1 - 0.027 14.6 1.7 0.11 12.6 0.1 2.3 2 0 0 2 2 2 0 RecX family Mg_chelatase_2 PF13335.1 KFX99090.1 - 0.065 13.6 1.1 0.22 11.9 0.3 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Cbl_N PF02262.11 KFX99090.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Glyco_tranf_2_4 PF13704.1 KFX99090.1 - 0.19 12.0 3.8 0.94 9.8 0.0 3.0 3 1 0 3 3 3 0 Glycosyl transferase family 2 RRS1 PF04939.7 KFX99091.1 - 1.7e-56 190.1 2.3 2e-56 189.9 1.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PH PF00169.24 KFX99092.1 - 6.3e-08 32.7 0.2 1.1e-07 31.9 0.2 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 KFX99092.1 - 0.02 15.1 1.6 0.19 11.9 1.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 KFX99092.1 - 0.032 14.4 0.4 0.058 13.5 0.3 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.27 KFX99095.1 - 2.9e-08 33.3 0.4 0.037 13.9 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat IGF2_C PF08365.6 KFX99095.1 - 0.072 12.8 0.3 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Bim_N PF06773.6 KFX99095.1 - 0.12 12.1 7.8 0.14 11.9 1.2 3.2 3 0 0 3 3 3 0 Bim protein N-terminus HRXXH PF13933.1 KFX99104.1 - 2.1e-95 318.8 0.0 2.7e-95 318.4 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.17 KFX99105.1 - 1.4e-36 126.1 12.7 1.4e-36 126.1 8.8 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter Arf PF00025.16 KFX99118.1 - 3e-76 254.5 0.1 4e-76 254.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFX99118.1 - 1.4e-13 50.5 0.0 2.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFX99118.1 - 1.2e-12 47.5 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFX99118.1 - 2.1e-11 43.1 1.0 2.5e-09 36.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFX99118.1 - 1.3e-10 40.8 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFX99118.1 - 5.3e-08 33.3 0.0 8.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX99118.1 - 8.9e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nucleoporin_N PF08801.6 KFX99118.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like 6PF2K PF01591.13 KFX99118.1 - 0.028 13.5 0.1 0.06 12.4 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 KFX99118.1 - 0.14 12.0 0.1 0.36 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 KFX99119.1 - 5.4e-35 120.7 0.0 6.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1627 PF07789.7 KFX99119.1 - 0.047 13.2 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) DUF4131 PF13567.1 KFX99120.1 - 0.052 12.9 1.9 0.056 12.8 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 KFX99120.1 - 4.9 7.4 6.4 3.8e+02 1.3 4.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Fe_hyd_lg_C PF02906.9 KFX99121.1 - 3.2e-67 226.7 0.0 5.5e-67 226.0 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.2 KFX99122.1 - 2.4e-05 24.7 4.0 2.4e-05 24.7 2.8 3.5 2 2 0 2 2 2 1 SUZ domain API5 PF05918.6 KFX99122.1 - 0.086 11.3 3.2 0.1 11.0 2.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2744 PF10910.3 KFX99122.1 - 1.4 8.7 4.3 12 5.7 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2744) 2-Hacid_dh_C PF02826.14 KFX99124.1 - 4.8e-54 182.2 0.0 1.9e-53 180.2 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX99124.1 - 8.8e-17 60.8 0.0 1.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain zf-H2C2_2 PF13465.1 KFX99124.1 - 1.4e-05 25.0 0.5 1.4e-05 25.0 0.3 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFX99124.1 - 0.00033 20.8 0.2 0.00033 20.8 0.1 3.4 3 1 0 3 3 3 1 Zinc finger, C2H2 type NAD_binding_2 PF03446.10 KFX99124.1 - 0.00095 19.0 0.3 0.0018 18.1 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2_4 PF13894.1 KFX99124.1 - 0.018 15.3 9.0 0.028 14.7 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Aldo_ket_red PF00248.16 KFX99125.1 - 8.7e-52 175.6 0.0 9.9e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 KFX99126.1 - 2.1e-32 109.7 7.0 1.4e-09 37.5 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KFX99126.1 - 3.7e-05 22.0 0.3 0.00077 17.7 0.0 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFX99126.1 - 0.0032 16.9 0.2 0.015 14.7 0.0 1.9 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 KFX99126.1 - 0.0061 14.8 0.0 0.82 7.9 0.0 2.1 1 1 0 2 2 2 2 Cytochrome D1 heme domain JmjC PF02373.17 KFX99134.1 - 1.3e-09 38.2 0.2 4.3e-09 36.6 0.2 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KFX99134.1 - 0.00033 20.7 8.8 0.00033 20.7 6.1 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KFX99134.1 - 0.014 14.9 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 KFX99135.1 - 3.5e-32 111.6 23.7 4.8e-32 111.1 16.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family UPF0061 PF02696.9 KFX99137.1 - 2.8e-123 411.7 0.0 5.6e-123 410.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Ank_2 PF12796.2 KFX99137.1 - 1.7e-22 79.5 0.3 1.1e-13 51.2 0.3 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX99137.1 - 1.3e-16 59.5 2.5 0.0011 18.6 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KFX99137.1 - 1.3e-16 60.2 0.7 3.8e-07 30.1 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX99137.1 - 3.5e-16 59.2 0.4 1.1e-06 28.9 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99137.1 - 9.7e-11 40.8 0.3 0.17 12.1 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat AAA_22 PF13401.1 KFX99137.1 - 0.00096 19.3 0.1 0.0093 16.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KFX99137.1 - 0.063 12.9 0.0 0.69 9.5 0.0 2.6 2 1 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 KFX99137.1 - 0.076 13.8 0.0 0.46 11.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX99137.1 - 0.081 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldo_ket_red PF00248.16 KFX99138.1 - 9.4e-52 175.5 0.0 1.1e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.14 KFX99138.1 - 0.045 13.6 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain Striatin PF08232.7 KFX99142.1 - 1.6e-34 119.0 0.3 1.6e-34 119.0 0.2 2.8 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 KFX99142.1 - 1.1e-33 113.9 16.6 7.8e-10 38.2 0.1 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat ABC2_membrane PF01061.19 KFX99143.1 - 1.2e-92 308.7 60.0 5.7e-49 166.1 12.7 3.9 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KFX99143.1 - 4.3e-40 135.5 0.3 2.4e-32 110.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KFX99143.1 - 1.4e-39 135.4 0.0 7.1e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KFX99143.1 - 1.6e-20 72.9 0.0 2.5e-19 69.1 0.0 2.6 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFX99143.1 - 3.4e-08 33.1 0.0 0.00024 20.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KFX99143.1 - 9.3e-06 24.9 0.2 0.0023 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 KFX99143.1 - 1e-05 25.4 0.2 0.0084 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX99143.1 - 2.8e-05 24.1 1.6 0.0034 17.3 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.14 KFX99143.1 - 0.00015 21.3 2.7 0.0076 15.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KFX99143.1 - 0.0016 19.2 0.0 0.82 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX99143.1 - 0.0027 16.9 0.0 0.11 11.6 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX99143.1 - 0.0027 17.1 2.2 0.054 13.0 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KFX99143.1 - 0.0028 16.7 21.5 0.0028 16.7 14.9 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.1 KFX99143.1 - 0.0085 16.4 0.2 1.1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFX99143.1 - 0.0088 16.0 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFX99143.1 - 0.011 16.2 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KFX99143.1 - 0.037 13.6 1.8 5.2 6.6 0.1 2.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 KFX99143.1 - 0.041 13.8 0.0 4.9 7.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX99143.1 - 0.075 13.1 1.3 3.7 7.7 0.2 2.9 2 1 0 2 2 2 0 AAA domain PDR_assoc PF08370.6 KFX99143.1 - 0.16 11.5 7.1 0.32 10.5 0.2 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_19 PF13245.1 KFX99143.1 - 0.74 9.6 5.5 5.7 6.7 0.1 3.2 3 0 0 3 3 2 0 Part of AAA domain AAA_10 PF12846.2 KFX99143.1 - 2.5 7.4 4.4 13 5.1 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain WSC PF01822.14 KFX99144.1 - 1.3e-39 133.9 23.3 1.2e-20 73.1 6.7 2.8 3 0 0 3 3 3 2 WSC domain Amidase PF01425.16 KFX99144.1 - 6.5 5.4 9.0 11 4.7 6.3 1.3 1 0 0 1 1 1 0 Amidase PIG-P PF08510.7 KFX99145.1 - 5.5e-42 142.3 0.1 1.8e-41 140.6 0.1 2.0 1 0 0 1 1 1 1 PIG-P MFS_1 PF07690.11 KFX99145.1 - 9.4e-37 126.5 55.4 9.4e-37 126.5 38.4 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF605 PF04652.11 KFX99145.1 - 0.094 12.0 4.1 0.15 11.4 2.9 1.2 1 0 0 1 1 1 0 Vta1 like Acetyltransf_1 PF00583.19 KFX99146.1 - 0.019 14.9 0.0 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX99146.1 - 0.023 14.7 0.2 1 9.5 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF664 PF04978.7 KFX99146.1 - 0.031 14.5 0.1 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Acetyltransf_7 PF13508.1 KFX99146.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3328 PF11807.3 KFX99147.1 - 1.2e-26 93.7 0.0 1.7e-26 93.2 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) GMC_oxred_N PF00732.14 KFX99148.1 - 5e-63 213.0 0.0 6.2e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX99148.1 - 1.1e-37 129.4 0.0 1.9e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX99148.1 - 3.2e-05 23.0 0.0 0.00096 18.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX99148.1 - 0.00036 19.5 0.1 0.0018 17.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KFX99148.1 - 0.00039 19.4 0.1 0.00094 18.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX99148.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 3.0 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX99148.1 - 0.0066 16.3 0.1 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX99148.1 - 0.015 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KFX99148.1 - 0.025 13.0 0.2 0.29 9.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 KFX99148.1 - 0.039 14.0 0.1 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX99148.1 - 0.099 12.4 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3328 PF11807.3 KFX99150.1 - 5e-53 179.9 0.0 6.3e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.20 KFX99151.1 - 6.1e-09 36.0 0.0 8.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99151.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFX99151.1 - 0.084 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Hist_deacetyl PF00850.14 KFX99152.1 - 1.7e-91 306.7 0.0 2.7e-91 306.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KFX99152.1 - 1.2e-36 125.8 0.2 1.7e-36 125.3 0.2 1.2 1 0 0 1 1 1 1 Arb2 domain Glyco_hydro_61 PF03443.9 KFX99153.1 - 1.9e-57 194.5 0.3 2.6e-57 194.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KFX99153.1 - 6.7e-05 22.4 8.3 6.7e-05 22.4 5.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.9 KFX99154.1 - 3.5e-69 232.9 0.1 4.5e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 KFX99154.1 - 0.062 12.9 0.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 Wzt C-terminal domain Phage_Coat_B PF05356.6 KFX99154.1 - 1.9 8.2 4.5 1.8 8.2 1.1 2.2 2 0 0 2 2 2 0 Phage Coat protein B Ank_2 PF12796.2 KFX99155.1 - 2.6e-21 75.7 0.1 1.3e-07 31.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX99155.1 - 1.5e-18 66.3 0.3 1.7e-10 40.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX99155.1 - 1.5e-16 60.3 0.7 1.9e-07 31.3 0.0 4.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KFX99155.1 - 1.5e-14 52.9 0.1 2.7e-07 30.0 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFX99155.1 - 5.9e-13 47.6 0.1 0.00028 20.8 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat TPR_12 PF13424.1 KFX99155.1 - 1.9e-07 30.8 0.4 0.025 14.4 0.0 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat NACHT PF05729.7 KFX99155.1 - 9.9e-07 28.5 0.0 2.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX99155.1 - 1.3e-05 25.3 0.0 0.00012 22.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX99155.1 - 9.9e-05 22.3 0.0 0.00039 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KFX99155.1 - 0.026 14.7 0.0 0.12 12.5 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1325 PF07039.6 KFX99156.1 - 2.7e-27 94.9 0.0 3.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF3232 PF11554.3 KFX99156.1 - 0.0036 17.2 0.1 0.0054 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3232) DUF4537 PF15057.1 KFX99156.1 - 0.07 12.9 0.2 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) PIF1 PF05970.9 KFX99163.1 - 2.5e-58 197.7 0.3 3.4e-45 154.5 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KFX99163.1 - 1.2e-17 64.1 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX99163.1 - 3e-06 27.3 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX99163.1 - 1.4e-05 24.7 0.2 3.5e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 KFX99163.1 - 5.2e-05 21.2 0.1 0.00046 18.0 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 KFX99163.1 - 0.00012 22.2 0.1 0.00066 19.7 0.1 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 KFX99163.1 - 0.00026 20.2 0.0 0.00063 19.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 KFX99163.1 - 0.0023 16.9 0.2 0.004 16.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KFX99163.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX99163.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 KFX99163.1 - 0.013 14.4 0.1 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 KFX99163.1 - 0.014 14.9 0.0 0.041 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KFX99163.1 - 0.015 14.8 0.1 3 7.3 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KFX99163.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 KFX99163.1 - 0.05 12.2 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activ_2 PF14532.1 KFX99163.1 - 0.073 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFX99163.1 - 0.076 12.1 0.1 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KFX99163.1 - 0.078 12.6 0.1 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KFX99163.1 - 0.092 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KFX99163.1 - 0.12 11.1 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KFX99163.1 - 0.13 12.1 0.0 0.62 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX99163.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.2 KFX99163.1 - 0.14 11.2 0.1 0.33 9.9 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region D3 IstB_IS21 PF01695.12 KFX99163.1 - 0.14 11.5 0.0 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein zf-CCHC PF00098.18 KFX99163.1 - 1.9 8.5 5.7 3.3 7.8 4.0 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.17 KFX99164.1 - 2.9e-58 193.4 0.0 6.7e-20 70.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX99164.1 - 2.2e-44 149.3 0.0 7.5e-15 54.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX99164.1 - 5.9e-31 106.1 0.0 5.7e-11 42.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX99164.1 - 7.5e-07 28.8 0.1 0.0083 15.8 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KFX99164.1 - 0.03 14.0 0.0 53 3.6 0.0 3.3 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Med2 PF11214.3 KFX99165.1 - 0.0035 17.3 0.3 0.037 14.0 0.1 2.5 2 1 0 2 2 2 1 Mediator complex subunit 2 Synapsin_N PF10581.4 KFX99180.1 - 0.12 12.2 0.3 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Synapsin N-terminal Palm_thioest PF02089.10 KFX99181.1 - 6.1e-22 77.8 0.1 7.3e-22 77.6 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Cyclin_N PF00134.18 KFX99182.1 - 5.9e-08 32.3 0.0 8.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain tRNA-synt_2b PF00587.20 KFX99183.1 - 8.7e-22 77.5 0.0 1.2e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFX99183.1 - 6.6e-10 38.9 0.9 1.6e-09 37.7 0.6 1.7 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain HIGH_NTase1 PF05636.6 KFX99183.1 - 0.11 11.5 0.2 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase DIL PF01843.14 KFX99184.1 - 6.6e-21 74.1 0.9 1.2e-12 47.6 0.2 2.5 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 KFX99184.1 - 1.5e-15 57.2 0.0 3.5e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX99184.1 - 1.2e-14 53.3 0.0 2.1e-05 24.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFX99184.1 - 3.7e-11 42.9 0.0 8e-07 29.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX99184.1 - 9.6e-11 41.9 0.0 1.1e-05 25.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99184.1 - 8e-07 28.7 0.0 0.3 11.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat P_C PF06640.6 KFX99184.1 - 0.0031 17.5 0.7 0.0031 17.5 0.5 1.7 2 0 0 2 2 2 1 P protein C-terminus Oxidored_FMN PF00724.15 KFX99185.1 - 5.9e-90 301.6 0.0 6.8e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KFX99185.1 - 0.062 12.5 0.0 1.6 7.9 0.0 2.7 1 1 1 3 3 3 0 Xylose isomerase-like TIM barrel DUF2968 PF11180.3 KFX99186.1 - 0.0014 18.0 19.8 0.17 11.2 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2968) Packaging_FI PF14000.1 KFX99186.1 - 0.021 14.9 0.1 0.021 14.9 0.1 2.3 2 0 0 2 2 2 0 DNA packaging protein FI Vps5 PF09325.5 KFX99186.1 - 0.066 12.4 10.8 0.16 11.1 4.3 2.3 2 0 0 2 2 2 0 Vps5 C terminal like COX6C PF02937.10 KFX99186.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF2730 PF10805.3 KFX99186.1 - 0.16 11.7 4.1 0.5 10.1 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) IFP_35_N PF07334.8 KFX99186.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Apolipoprotein PF01442.13 KFX99186.1 - 0.3 10.5 16.9 1.4 8.3 11.2 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain ADIP PF11559.3 KFX99186.1 - 2.3 8.1 16.9 0.28 11.0 0.3 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 KFX99186.1 - 3 8.2 10.6 21 5.5 0.1 3.8 3 1 0 3 3 3 0 SlyX FlxA PF14282.1 KFX99186.1 - 4.8 7.1 22.9 9.6 6.2 6.8 3.8 4 0 0 4 4 4 0 FlxA-like protein CP12 PF02672.10 KFX99186.1 - 6.8 7.2 21.6 6.1 7.3 0.2 3.5 3 0 0 3 3 3 0 CP12 domain DUF4446 PF14584.1 KFX99186.1 - 8.3 6.2 7.7 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Cytochrom_B561 PF03188.11 KFX99187.1 - 5e-16 58.7 6.2 1.1e-15 57.6 4.3 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3425 PF11905.3 KFX99187.1 - 2.6e-07 30.6 2.1 4.7e-07 29.7 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX99187.1 - 0.0015 18.4 5.1 0.0026 17.6 3.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor PepSY_TM_2 PF13703.1 KFX99187.1 - 0.028 14.5 8.6 1.4 9.1 0.0 3.7 2 1 0 2 2 2 0 PepSY-associated TM helix DUF418 PF04235.7 KFX99187.1 - 0.25 11.0 11.1 0.035 13.7 3.3 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF418) Ni_hydr_CYTB PF01292.15 KFX99187.1 - 0.67 9.3 11.1 10 5.4 7.8 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4267 PF14087.1 KFX99188.1 - 4.4e-06 26.2 1.0 7.4e-06 25.5 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) FYVE PF01363.16 KFX99189.1 - 4.7 7.1 10.4 62 3.5 7.2 2.5 1 1 0 1 1 1 0 FYVE zinc finger SET PF00856.23 KFX99195.1 - 6.6e-05 23.2 0.0 0.016 15.5 0.0 2.5 2 1 0 2 2 2 2 SET domain zf-MYND PF01753.13 KFX99195.1 - 0.00081 19.2 7.3 0.00081 19.2 5.1 2.3 2 0 0 2 2 2 1 MYND finger Glucosamine_iso PF01182.15 KFX99196.1 - 5.1e-61 205.8 0.0 5.9e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PP2C PF00481.16 KFX99205.1 - 2.1e-83 279.6 0.1 3.4e-83 278.9 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFX99205.1 - 1.5e-05 24.5 0.0 4.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C ALS_ss_C PF10369.4 KFX99229.1 - 4.6e-18 64.7 0.0 6.9e-17 60.9 0.0 2.5 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KFX99229.1 - 1.1e-12 47.1 0.1 2.6e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KFX99229.1 - 1e-09 38.0 0.0 1.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF1949 PF09186.6 KFX99229.1 - 0.14 11.7 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DUF3712 PF12505.3 KFX99230.1 - 3.7e-07 30.1 4.1 1.5e-05 24.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KFX99230.1 - 0.00073 19.8 3.7 7.9 6.9 0.0 4.8 5 0 0 5 5 5 2 Late embryogenesis abundant protein OTCace_N PF02729.16 KFX99231.1 - 3.6e-44 149.8 0.2 7.6e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KFX99231.1 - 5.4e-39 133.5 0.0 8.6e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Mpp10 PF04006.7 KFX99232.1 - 8.7e-92 308.4 94.2 7e-90 302.1 63.4 2.5 1 1 0 1 1 1 1 Mpp10 protein Oxidored_q6 PF01058.17 KFX99233.1 - 3.8e-22 78.2 0.0 5.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Zn_clus PF00172.13 KFX99234.1 - 3.6e-06 26.7 6.2 7.4e-06 25.7 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX99234.1 - 8.9e-05 21.4 0.0 0.00019 20.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SART-1 PF03343.8 KFX99236.1 - 2.2e-166 554.8 67.0 2.5e-166 554.6 46.4 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.16 KFX99237.1 - 5.9e-100 334.9 0.0 7e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KFX99237.1 - 1.7e-31 107.6 0.6 5.5e-31 106.0 0.4 1.9 1 0 0 1 1 1 1 Starch binding domain CBM_25 PF03423.8 KFX99237.1 - 0.058 13.4 1.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) PRCC PF10253.4 KFX99238.1 - 0.77 10.4 6.8 1 9.9 2.1 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting zinc_ribbon_6 PF14599.1 KFX99239.1 - 6.8e-26 89.8 0.6 9.7e-26 89.3 0.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon DUF3984 PF13136.1 KFX99240.1 - 2.1e-66 224.3 21.1 5.4e-66 223.0 14.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) Corona_nucleoca PF00937.13 KFX99240.1 - 0.00062 18.8 0.6 0.00062 18.8 0.4 2.2 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein DENN PF02141.16 KFX99242.1 - 2.5e-56 190.3 0.0 4.7e-56 189.4 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFX99242.1 - 5.5e-17 61.4 0.0 1.7e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFX99242.1 - 6.5e-16 58.1 0.7 6.5e-16 58.1 0.5 2.0 2 0 0 2 2 2 1 dDENN domain C1_1 PF00130.17 KFX99242.1 - 0.0076 15.9 4.1 0.013 15.1 2.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 KFX99242.1 - 0.011 15.7 3.9 0.02 14.9 2.7 1.4 1 0 0 1 1 1 0 C1 domain PHD PF00628.24 KFX99242.1 - 0.032 13.9 2.4 0.063 12.9 1.7 1.5 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 KFX99242.1 - 0.044 13.8 3.6 0.077 13.0 2.5 1.4 1 0 0 1 1 1 0 C1-like domain SPA PF08616.5 KFX99242.1 - 0.23 11.1 0.2 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Stabilization of polarity axis Chitin_bind_3 PF03067.10 KFX99248.1 - 9.8e-09 35.7 1.2 1.1e-08 35.5 0.8 1.1 1 0 0 1 1 1 1 Chitin binding domain Fungal_trans_2 PF11951.3 KFX99249.1 - 9.2e-07 27.7 0.6 1.1e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99249.1 - 3e-06 27.0 9.8 5.9e-06 26.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF899 PF05988.7 KFX99249.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) RTA1 PF04479.8 KFX99250.1 - 1.9e-17 63.5 4.6 3.9e-17 62.4 3.2 1.5 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 KFX99250.1 - 4.1 6.7 7.1 69 2.7 0.2 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase p450 PF00067.17 KFX99251.1 - 3.9e-53 180.6 0.0 4.9e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MepB PF08877.5 KFX99251.1 - 0.057 12.9 0.1 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 MepB protein TRI12 PF06609.8 KFX99253.1 - 4.5e-26 91.1 26.0 5.4e-26 90.9 18.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX99253.1 - 1.7e-21 76.3 48.2 1.7e-21 76.3 33.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4141 PF13605.1 KFX99253.1 - 0.04 13.1 0.6 0.15 11.2 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) DUF2301 PF10063.4 KFX99253.1 - 1.1 9.5 10.9 0.84 9.8 0.9 3.5 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) Zn_clus PF00172.13 KFX99255.1 - 1.3e-08 34.6 10.9 2.4e-08 33.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX99255.1 - 3e-08 32.6 0.6 4.2e-08 32.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 KFX99256.1 - 0.28 10.9 0.0 0.56 9.9 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RWD PF05773.17 KFX99261.1 - 7.8e-19 67.6 0.0 1.6e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KFX99261.1 - 4.9e-18 64.7 29.3 4.5e-11 42.4 1.1 3.8 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KFX99261.1 - 4e-05 23.3 6.3 4e-05 23.3 4.4 3.8 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 KFX99261.1 - 0.00064 19.3 4.1 0.00064 19.3 2.9 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KFX99261.1 - 0.0011 19.0 7.5 0.0011 19.0 5.2 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX99261.1 - 0.0017 18.0 6.0 0.0017 18.0 4.2 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX99261.1 - 0.004 16.7 4.9 0.004 16.7 3.4 4.4 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX99261.1 - 0.045 13.6 0.8 0.045 13.6 0.6 4.5 5 1 0 5 5 4 0 zinc finger of C3HC4-type, RING DUF1244 PF06844.6 KFX99261.1 - 0.082 12.7 2.5 0.98 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) FYVE PF01363.16 KFX99261.1 - 1.5 8.7 26.8 3.2 7.7 5.3 3.5 2 1 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.1 KFX99261.1 - 4.3 6.9 15.4 0.71 9.4 1.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 NDT80_PhoG PF05224.7 KFX99262.1 - 1.5e-30 106.5 0.0 4.6e-30 104.9 0.0 1.9 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.5 KFX99263.1 - 3.8e-21 75.3 19.2 1.5e-20 73.4 13.3 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) CAF-1_p150 PF11600.3 KFX99263.1 - 0.05 12.9 15.8 0.083 12.2 11.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal tRNA-synt_1 PF00133.17 KFX99264.1 - 8.7e-59 199.0 0.0 1.8e-35 122.0 0.0 6.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KFX99264.1 - 1.3e-41 141.9 0.0 2.2e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KFX99264.1 - 3.6e-28 98.3 0.0 1.7e-20 73.0 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFX99264.1 - 7.7e-12 45.2 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 KFX99264.1 - 0.0098 14.7 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 KFX99264.1 - 0.011 14.8 0.0 0.29 10.2 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain AA_permease_2 PF13520.1 KFX99265.1 - 6e-64 216.1 36.0 7.8e-64 215.7 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX99265.1 - 3.5e-29 101.4 27.2 3.5e-29 101.4 18.9 2.0 2 0 0 2 2 2 2 Amino acid permease Glyco_hydro_43 PF04616.9 KFX99267.1 - 2.2e-12 46.6 0.5 4.7e-12 45.6 0.1 1.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 43 zf-C3HC4 PF00097.20 KFX99268.1 - 6e-09 35.4 3.9 6e-09 35.4 2.7 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX99268.1 - 1.8e-07 30.9 4.8 1.8e-07 30.9 3.3 3.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX99268.1 - 1.1e-06 28.5 1.5 1.1e-06 28.5 1.0 4.4 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX99268.1 - 9.9e-06 25.1 3.6 9.9e-06 25.1 2.5 4.7 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFX99268.1 - 2.3e-05 24.1 0.7 2.3e-05 24.1 0.5 3.3 3 2 0 3 3 3 1 zf-RING of BARD1-type protein GAGA PF09237.6 KFX99268.1 - 0.00035 20.1 1.6 0.0054 16.2 0.4 2.8 2 0 0 2 2 2 1 GAGA factor zf-RING_UBOX PF13445.1 KFX99268.1 - 0.0011 18.6 1.5 0.0029 17.2 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX99268.1 - 0.0035 17.1 5.5 0.0035 17.1 3.8 4.2 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING FAD_binding_3 PF01494.14 KFX99270.1 - 1.6e-28 99.8 0.0 3e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KFX99270.1 - 5.6e-05 22.1 0.0 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.7 KFX99270.1 - 0.00076 18.4 0.0 2.4 6.9 0.0 3.8 3 1 1 4 4 4 2 Lycopene cyclase protein DAO PF01266.19 KFX99270.1 - 0.0065 15.4 0.1 2.6 6.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX99270.1 - 0.0072 16.3 0.1 0.024 14.6 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX99270.1 - 0.0075 16.6 0.1 2.4 8.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.14 KFX99270.1 - 0.19 11.4 0.7 19 5.0 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain NAD_binding_10 PF13460.1 KFX99271.1 - 1.4e-27 96.9 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX99271.1 - 4.4e-08 32.8 0.0 8.2e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX99271.1 - 6.8e-07 28.7 0.1 9.5e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KFX99271.1 - 0.032 14.2 0.1 0.17 11.9 0.0 2.3 2 1 1 3 3 3 0 TrkA-N domain NAD_binding_4 PF07993.7 KFX99271.1 - 0.11 11.4 0.0 3.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Fungal_trans PF04082.13 KFX99272.1 - 3.6e-12 45.6 0.1 6.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99272.1 - 4.5e-06 26.4 11.0 9.2e-06 25.4 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSase_L_D2 PF02786.12 KFX99274.1 - 1.6e-58 197.4 0.0 2.3e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFX99274.1 - 1.3e-30 105.5 0.0 2.4e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFX99274.1 - 1e-24 86.7 0.0 2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX99274.1 - 9.4e-16 58.0 0.1 1.9e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX99274.1 - 8.6e-14 51.0 0.0 2.1e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KFX99274.1 - 8.2e-11 41.3 2.6 2.9e-10 39.6 1.9 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KFX99274.1 - 2.6e-07 30.2 0.0 5.5e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFX99274.1 - 3.2e-05 23.3 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFX99274.1 - 0.00016 21.5 0.0 0.00039 20.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KFX99274.1 - 0.011 15.1 0.0 0.067 12.6 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 KFX99274.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF2118 PF09891.4 KFX99274.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Carboxyl_trans PF01039.17 KFX99275.1 - 3.2e-73 246.7 0.0 4.1e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain OATP PF03137.15 KFX99275.1 - 0.13 10.2 0.3 0.2 9.6 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KFX99276.1 - 2e-34 118.8 28.2 3.1e-34 118.2 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KFX99277.1 - 9.6e-29 100.0 0.3 1.4e-28 99.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 KFX99278.1 - 7.6e-53 179.3 0.0 1.1e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX99278.1 - 2.4e-06 28.3 0.0 5.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YbbR PF07949.7 KFX99279.1 - 0.075 13.1 1.0 0.097 12.8 0.7 1.3 1 0 0 1 1 1 0 YbbR-like protein bZIP_2 PF07716.10 KFX99281.1 - 5e-05 23.0 25.1 0.00022 20.9 16.5 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFX99281.1 - 0.0012 18.7 19.6 0.0047 16.8 13.7 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KFX99281.1 - 0.045 14.0 14.8 0.08 13.2 10.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 KFX99281.1 - 0.73 8.8 5.3 0.96 8.4 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1761 PF08570.5 KFX99283.1 - 4.6e-25 88.0 3.0 5.2e-25 87.8 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) QCR10 PF09796.4 KFX99283.1 - 1.8 8.3 6.3 3 7.5 0.4 3.1 1 1 2 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_hydro_15 PF00723.16 KFX99286.1 - 1.7e-21 76.3 0.0 2.6e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 6PGD PF00393.14 KFX99300.1 - 2.6e-133 443.7 0.0 3.1e-133 443.4 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFX99300.1 - 8.3e-35 120.0 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFX99300.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MFS_1 PF07690.11 KFX99301.1 - 1.7e-33 115.7 21.5 1.7e-33 115.7 14.9 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily NACHT PF05729.7 KFX99301.1 - 3.8e-06 26.6 0.1 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 KFX99301.1 - 0.00016 21.3 0.0 0.00053 19.6 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.1 KFX99301.1 - 0.00041 20.3 0.0 0.00094 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.9 KFX99301.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KFX99301.1 - 0.0021 17.9 0.0 0.014 15.3 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KFX99301.1 - 0.15 12.2 0.0 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fructosamin_kin PF03881.9 KFX99302.1 - 3.2e-33 114.9 0.0 4.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFX99302.1 - 0.00045 20.0 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.17 KFX99303.1 - 1.8e-50 171.7 0.0 2.7e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KFX99303.1 - 1.4e-46 158.8 0.0 5.4e-25 88.0 0.0 3.4 2 2 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99303.1 - 3.6e-10 39.3 0.0 0.0032 16.5 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase DUF4025 PF13217.1 KFX99304.1 - 0.037 13.8 0.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4025) GlcNAc_2-epim PF07221.6 KFX99305.1 - 0.062 12.2 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Atx10homo_assoc PF09759.4 KFX99306.1 - 1e-14 54.1 0.0 3e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.24 KFX99306.1 - 2e-12 46.5 1.0 9.4e-09 34.8 0.1 3.5 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 KFX99306.1 - 8.3e-11 41.2 1.2 9.3e-10 37.9 0.4 2.5 2 0 0 2 2 2 1 KH domain DUF2408 PF10303.4 KFX99306.1 - 0.031 14.3 0.6 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF2521 PF10730.4 KFX99306.1 - 0.033 13.9 0.3 7 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2521) BMC PF00936.14 KFX99306.1 - 0.036 13.7 0.2 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 BMC domain Glyoxalase PF00903.20 KFX99307.1 - 5e-35 120.2 0.0 2e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX99307.1 - 8e-30 103.6 0.0 2e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFX99307.1 - 1.3e-14 54.1 0.0 5.7e-06 26.2 0.0 3.4 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFX99307.1 - 4.4e-06 26.7 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain GFA PF04828.9 KFX99309.1 - 5.7e-25 87.0 0.1 8e-25 86.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acetyltransf_2 PF00797.12 KFX99310.1 - 5.4e-42 144.0 0.0 7.6e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase DUF2434 PF10361.4 KFX99312.1 - 9e-113 376.2 0.5 1.2e-112 375.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF805 PF05656.9 KFX99312.1 - 0.016 15.0 3.6 0.52 10.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF1876 PF08962.6 KFX99320.1 - 0.047 13.4 0.6 0.071 12.8 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1876) PNPOx_C PF10590.4 KFX99326.1 - 0.11 11.9 1.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pectate_lyase_3 PF12708.2 KFX99327.1 - 3.3e-79 266.1 22.6 5.9e-61 206.4 6.8 3.5 2 1 1 3 3 3 2 Pectate lyase superfamily protein PAN_3 PF08277.7 KFX99327.1 - 8.2e-07 28.5 31.5 0.026 14.1 0.6 5.0 5 0 0 5 5 5 4 PAN-like domain End_N_terminal PF12218.3 KFX99327.1 - 2.6e-06 26.8 3.6 0.03 13.7 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PAN_4 PF14295.1 KFX99327.1 - 1.6 8.4 37.2 0.67 9.7 1.5 5.4 5 0 0 5 5 5 0 PAN domain Amidase PF01425.16 KFX99340.1 - 2.4e-41 142.0 0.1 3.4e-41 141.5 0.1 1.2 1 0 0 1 1 1 1 Amidase ADH_N PF08240.7 KFX99341.1 - 5.7e-18 64.6 0.3 1e-17 63.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX99341.1 - 1.4e-06 27.8 0.0 0.00066 19.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFX99341.1 - 0.00069 19.2 1.2 0.0016 18.0 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Peptidase_S28 PF05577.7 KFX99342.1 - 2.3e-52 178.0 1.0 7.2e-39 133.5 0.1 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 adh_short PF00106.20 KFX99343.1 - 1.5e-15 57.5 0.1 1.2e-14 54.6 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99343.1 - 4.2e-08 33.2 0.0 2.4e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX99343.1 - 4.3e-05 23.2 0.0 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX99343.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX99343.1 - 0.11 12.4 0.0 0.45 10.4 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding Aldo_ket_red PF00248.16 KFX99344.1 - 1.3e-62 211.2 0.0 1.8e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 KFX99361.1 - 4.8e-10 38.9 1.5 2.5e-05 23.9 0.0 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat DNA_pol_A_exo1 PF01612.15 KFX99362.1 - 1.1e-13 51.0 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.17 KFX99363.1 - 4.5e-18 64.5 0.1 8.3e-18 63.7 0.1 1.4 1 0 0 1 1 1 1 LSM domain RNA_pol_L_2 PF13656.1 KFX99364.1 - 1.4e-22 78.9 0.0 1.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFX99364.1 - 1.2e-10 40.3 0.0 1.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Amidase PF01425.16 KFX99369.1 - 6.8e-25 87.8 0.0 8.9e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Amidase DnaJ PF00226.26 KFX99370.1 - 1.9e-19 69.1 1.2 1.9e-19 69.1 0.8 2.4 2 1 0 2 2 2 1 DnaJ domain DUF4551 PF15087.1 KFX99370.1 - 0.13 10.6 9.8 0.22 9.8 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PspB PF06667.7 KFX99370.1 - 0.16 11.9 1.3 0.48 10.3 0.9 1.8 1 0 0 1 1 1 0 Phage shock protein B Complex1_LYR PF05347.10 KFX99371.1 - 1.2e-06 28.2 0.3 1.9e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX99371.1 - 6.4e-05 23.0 0.1 7.5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like ORC6 PF05460.8 KFX99378.1 - 1.3 8.0 8.2 1.5 7.8 5.7 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Lipase_GDSL PF00657.17 KFX99379.1 - 4.6e-07 29.9 1.0 7.1e-07 29.2 0.7 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX99379.1 - 1.3e-05 25.3 0.3 3.5e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Myb_DNA-bind_4 PF13837.1 KFX99380.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3115 PF11312.3 KFX99381.1 - 2.2e-37 128.6 0.0 2.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) adh_short PF00106.20 KFX99382.1 - 2e-18 66.8 0.0 2.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99382.1 - 1.2e-05 25.0 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX99382.1 - 0.00059 19.3 0.0 0.001 18.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX99382.1 - 0.0066 16.4 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KFX99382.1 - 0.14 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Crystall_3 PF08964.5 KFX99383.1 - 3.2e-08 33.1 0.1 4.4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Alpha_L_fucos PF01120.12 KFX99384.1 - 1.6e-26 93.0 0.0 9.9e-26 90.4 0.0 2.1 1 1 0 1 1 1 1 Alpha-L-fucosidase Nop16 PF09420.5 KFX99385.1 - 2e-53 180.8 9.8 2.4e-53 180.6 6.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 EHN PF06441.7 KFX99385.1 - 0.79 9.6 4.1 0.43 10.5 1.0 1.8 2 1 0 2 2 2 0 Epoxide hydrolase N terminus Activator-TraM PF11657.3 KFX99385.1 - 2.1 7.7 6.2 8.7 5.8 0.7 2.2 2 0 0 2 2 2 0 Transcriptional activator TraM NDUF_B4 PF07225.7 KFX99386.1 - 0.054 13.2 0.1 0.061 13.1 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) adh_short PF00106.20 KFX99393.1 - 4.5e-15 55.9 0.6 9e-15 54.9 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99393.1 - 1.9e-07 30.9 0.5 3.6e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KFX99394.1 - 0.00054 18.9 0.1 0.00088 18.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KFX99397.1 - 2.4e-25 89.4 0.1 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99397.1 - 6.1e-25 88.3 0.1 8.2e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX99397.1 - 3.4e-08 33.3 0.1 5.1e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX99397.1 - 3e-05 23.5 0.0 0.00017 21.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX99397.1 - 9.7e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KFX99397.1 - 0.0002 20.5 0.0 0.033 13.3 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.8 KFX99397.1 - 0.0018 17.5 0.1 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KFX99397.1 - 0.014 14.2 0.1 0.028 13.3 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain PAE PF03283.8 KFX99397.1 - 0.019 13.6 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DFP PF04127.10 KFX99397.1 - 0.087 12.4 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 KFX99397.1 - 0.098 12.4 0.1 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 KFX99397.1 - 0.11 13.1 0.0 0.21 12.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KFX99398.1 - 2.3e-24 85.7 23.9 2.3e-24 85.7 16.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX99398.1 - 2.4e-09 36.3 31.4 5.6e-09 35.0 21.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter zf-C2H2_4 PF13894.1 KFX99399.1 - 1.2e-06 28.4 25.7 0.11 12.8 0.7 6.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 KFX99399.1 - 1.1 9.6 9.4 1.3 9.3 0.1 4.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Transglut_i_TM PF14400.1 KFX99400.1 - 0.016 14.7 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices Glyco_hydro_65m PF03632.10 KFX99408.1 - 5e-76 255.7 2.7 5.4e-75 252.3 1.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KFX99408.1 - 3.2e-33 115.1 0.3 7.9e-33 113.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 KFX99408.1 - 0.064 13.0 0.0 0.064 13.0 0.0 3.7 5 1 1 6 6 6 0 F5/8 type C domain SpoU_methylase PF00588.14 KFX99409.1 - 5e-26 91.2 0.0 9.7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 KFX99409.1 - 2.6e-08 33.8 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 KFX99410.1 - 4.2e-70 234.5 7.1 9.9e-70 233.3 5.0 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KFX99410.1 - 8.1e-58 195.5 0.0 1.1e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KFX99410.1 - 7.9e-15 54.4 0.6 1.7e-14 53.3 0.4 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KFX99410.1 - 1.9e-12 46.8 0.0 5.9e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KFX99410.1 - 4.7e-08 32.5 0.4 0.00046 19.7 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KFX99410.1 - 2.6e-05 23.7 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 KFX99410.1 - 3.7e-05 23.3 2.8 3.7e-05 23.3 2.0 3.4 2 1 1 3 3 3 2 PHD-finger ResIII PF04851.10 KFX99410.1 - 7.2e-05 22.6 0.0 0.00031 20.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1087 PF06465.8 KFX99410.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) PHD_2 PF13831.1 KFX99410.1 - 0.1 11.9 11.6 0.0098 15.1 3.4 2.8 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 KFX99410.1 - 0.92 9.2 8.0 0.59 9.9 1.0 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ PF00226.26 KFX99416.1 - 6.6e-11 41.7 2.2 1.3e-10 40.7 1.6 1.6 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 KFX99418.1 - 1.3e-40 138.2 1.1 1.6e-40 137.9 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein 2TM PF13239.1 KFX99418.1 - 5.6 7.0 8.6 8.6 6.5 0.3 2.3 2 0 0 2 2 2 0 2TM domain SOBP PF15279.1 KFX99419.1 - 0.038 14.3 13.7 0.045 14.1 9.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein LCD1 PF09798.4 KFX99419.1 - 0.62 7.9 1.7 0.78 7.6 1.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4603 PF15376.1 KFX99419.1 - 1.1 6.3 11.6 1.3 6.0 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) adh_short PF00106.20 KFX99437.1 - 3.7e-18 65.9 0.3 6.2e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99437.1 - 1.1e-07 31.6 0.2 2.9e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX99437.1 - 0.0083 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KFX99437.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase But2 PF09792.4 KFX99438.1 - 1.1e-06 28.4 0.4 1.5e-06 27.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_1 PF00583.19 KFX99439.1 - 0.00086 19.2 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family adh_short PF00106.20 KFX99440.1 - 1.3e-20 74.0 0.0 2.2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99440.1 - 2.4e-14 53.6 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFX99440.1 - 4.8e-06 25.9 0.0 4.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFX99440.1 - 0.00023 21.2 0.1 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX99440.1 - 0.0063 15.8 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family PRAI PF00697.17 KFX99440.1 - 0.0078 15.7 0.1 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase NAD_binding_2 PF03446.10 KFX99440.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 KFX99441.1 - 2e-05 24.3 3.1 4.9e-05 23.1 2.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tn7_TnsC_Int PF11426.3 KFX99441.1 - 0.0031 17.1 0.6 0.063 13.0 0.1 2.5 2 0 0 2 2 2 1 Tn7 transposition regulator TnsC Abhydrolase_6 PF12697.2 KFX99442.1 - 2.1e-24 86.6 0.5 2.7e-24 86.3 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX99442.1 - 1.1e-10 41.5 0.4 1.5e-10 41.0 0.3 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX99442.1 - 8e-09 35.4 0.4 2.5e-08 33.8 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX99442.1 - 3.7e-07 29.8 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 KFX99442.1 - 0.056 12.2 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Tannase PF07519.6 KFX99443.1 - 1.9e-102 343.4 0.1 2.3e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KFX99443.1 - 4.8e-05 23.3 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX99443.1 - 0.00075 18.7 0.0 0.01 15.0 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFX99443.1 - 0.008 15.7 0.2 0.025 14.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Tubulin PF00091.20 KFX99445.1 - 2.9e-64 216.8 0.0 3.9e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX99445.1 - 1.9e-32 111.9 0.0 2.9e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 KFX99445.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF3591 PF12157.3 KFX99448.1 - 8e-195 647.5 1.6 1.1e-194 647.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KFX99448.1 - 0.013 15.1 2.4 0.031 13.9 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 KFX99448.1 - 0.025 14.4 1.1 0.043 13.7 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Meiotic_rec114 PF03525.9 KFX99448.1 - 0.093 11.2 2.0 0.36 9.2 0.5 2.1 2 0 0 2 2 2 0 Meiotic recombination protein rec114 WSC PF01822.14 KFX99452.1 - 1.9e-09 37.3 5.3 1.9e-09 37.3 3.7 1.6 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 KFX99452.1 - 2.9e-06 26.4 0.6 6e-06 25.4 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KFX99452.1 - 0.0031 17.0 0.2 0.0048 16.4 0.1 1.2 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.8 KFX99452.1 - 0.014 15.6 3.4 0.024 14.9 2.3 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4448 PF14610.1 KFX99452.1 - 0.023 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2263 PF10021.4 KFX99465.1 - 3.5e-24 85.4 0.0 5.1e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.13 KFX99466.1 - 2.7e-11 42.8 0.8 5.7e-11 41.7 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX99467.1 - 6.6e-27 94.1 58.8 1.6e-21 76.4 18.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX99467.1 - 0.0018 18.0 7.3 0.037 13.8 0.1 4.3 5 1 0 5 5 5 2 MFS_1 like family DUF3704 PF12488.3 KFX99467.1 - 0.074 12.6 2.6 0.21 11.1 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) RAP1 PF07218.6 KFX99468.1 - 0.014 13.5 11.3 0.017 13.2 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.6 KFX99468.1 - 0.37 9.0 18.3 0.45 8.7 12.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Sugar_tr PF00083.19 KFX99469.1 - 1.7e-56 191.7 27.6 2.1e-56 191.4 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99469.1 - 4.3e-22 78.3 26.9 6e-22 77.8 18.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 KFX99470.1 - 1.3e-63 214.8 0.0 1.8e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.13 KFX99471.1 - 1.9e-146 487.8 0.4 3.3e-146 487.0 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cupin_1 PF00190.17 KFX99471.1 - 2.1e-09 36.9 0.1 4.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KFX99471.1 - 0.00027 20.3 0.1 0.0006 19.2 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 KFX99471.1 - 0.034 13.5 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Sulfatase PF00884.18 KFX99472.1 - 2.1e-15 56.7 0.3 4.7e-15 55.5 0.1 1.7 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KFX99472.1 - 3.3e-06 26.6 0.6 6.6e-06 25.6 0.1 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Zn_clus PF00172.13 KFX99472.1 - 0.0044 16.8 18.9 0.0073 16.1 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX99473.1 - 3e-17 62.3 0.0 6e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99473.1 - 5.2e-06 26.2 12.4 1.1e-05 25.1 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX99474.1 - 4.4e-16 58.5 30.9 8.7e-14 50.9 7.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.19 KFX99475.1 - 4.8e-18 65.6 0.0 1.5e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX99475.1 - 2.3e-05 23.8 0.0 0.16 11.5 0.0 3.1 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, middle domain AMP-binding PF00501.23 KFX99476.1 - 2.3e-48 164.6 0.0 3.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Mito_carr PF00153.22 KFX99477.1 - 3.6e-62 206.1 0.5 4.8e-20 71.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.2 KFX99477.1 - 0.24 11.2 2.5 0.5 10.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Acyl-CoA_dh_1 PF00441.19 KFX99478.1 - 2.6e-24 86.0 0.1 4.1e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX99478.1 - 3.3e-24 85.6 0.1 6.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFX99478.1 - 8.7e-17 60.3 0.0 1.8e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX99478.1 - 4e-08 33.5 0.1 6.5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MARVEL PF01284.18 KFX99479.1 - 1.6e-14 53.9 15.5 2.5e-14 53.2 10.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF454 PF04304.8 KFX99479.1 - 0.012 15.6 1.2 0.012 15.6 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF454) ABC2_membrane_5 PF13346.1 KFX99479.1 - 0.066 12.4 11.8 0.23 10.7 8.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein YMF19 PF02326.10 KFX99479.1 - 0.27 11.8 0.0 0.27 11.8 0.0 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF3487 PF11990.3 KFX99479.1 - 0.33 10.3 3.8 0.26 10.7 1.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) PI3Ka PF00613.15 KFX99495.1 - 3.2e-58 195.9 0.3 5.1e-58 195.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFX99495.1 - 9e-42 143.1 0.0 4.1e-41 141.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KFX99495.1 - 1.9e-30 105.5 0.0 3.2e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4380 PF14315.1 KFX99502.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4380) PAM2 PF07145.10 KFX99503.1 - 0.07 12.6 0.8 0.25 10.9 0.1 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Baculo_PEP_C PF04513.7 KFX99504.1 - 0.00083 19.1 10.4 1.4 8.7 0.1 4.3 2 2 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3708 PF12501.3 KFX99504.1 - 0.021 14.7 1.4 0.23 11.3 0.1 2.9 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter DUF2523 PF10734.4 KFX99504.1 - 0.91 9.7 0.0 0.91 9.7 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2523) DUF1741 PF08427.5 KFX99505.1 - 2e-44 151.8 0.0 2.4e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fungal_trans PF04082.13 KFX99508.1 - 5.8e-24 84.3 0.0 1.2e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99508.1 - 0.0066 16.3 4.6 0.011 15.6 3.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps5 PF09325.5 KFX99508.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Vps5 C terminal like DUF2360 PF10152.4 KFX99508.1 - 0.21 11.8 1.0 0.37 11.0 0.7 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) VWA_2 PF13519.1 KFX99525.1 - 1e-05 25.7 0.1 2.4e-05 24.5 0.1 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX99525.1 - 0.0054 16.4 0.0 0.058 13.1 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain AAA PF00004.24 KFX99539.1 - 5.1e-17 62.3 0.0 1.1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFX99539.1 - 4.1e-13 49.3 0.0 2.4e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KFX99539.1 - 3.6e-11 42.4 0.0 1.3e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KFX99539.1 - 1.8e-10 40.6 0.1 5e-10 39.2 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 KFX99539.1 - 3.3e-07 29.5 0.3 3.2e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFX99539.1 - 6e-07 29.6 0.1 5.5e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFX99539.1 - 6.4e-07 29.1 0.2 1.6e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX99539.1 - 8.2e-07 29.1 0.1 0.00013 22.0 0.0 3.0 1 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KFX99539.1 - 1.7e-06 27.6 0.0 4.6e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFX99539.1 - 1e-05 25.2 0.5 3.9e-05 23.3 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFX99539.1 - 1.5e-05 23.9 0.0 0.07 11.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Sigma54_activat PF00158.21 KFX99539.1 - 1.7e-05 24.3 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 KFX99539.1 - 3e-05 23.7 0.1 0.00089 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KFX99539.1 - 3.1e-05 23.0 0.0 5.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 KFX99539.1 - 4.3e-05 23.0 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KFX99539.1 - 5.5e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFX99539.1 - 0.00028 20.4 0.1 0.0015 18.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KFX99539.1 - 0.0003 20.0 0.2 0.44 9.7 0.0 2.4 1 1 1 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KFX99539.1 - 0.00043 19.9 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KFX99539.1 - 0.00095 18.3 0.1 0.0078 15.4 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KFX99539.1 - 0.0029 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KFX99539.1 - 0.0036 16.7 0.2 0.44 9.9 0.1 2.7 1 1 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 KFX99539.1 - 0.0038 16.6 0.1 0.015 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFX99539.1 - 0.0039 16.6 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein DEAD PF00270.24 KFX99539.1 - 0.0041 16.6 0.0 0.08 12.4 0.0 2.4 2 1 1 3 3 2 1 DEAD/DEAH box helicase AAA_17 PF13207.1 KFX99539.1 - 0.011 16.4 0.0 0.024 15.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX99539.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX99539.1 - 0.027 14.6 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SNF2_N PF00176.18 KFX99539.1 - 0.035 12.9 0.0 2.6 6.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 KFX99539.1 - 0.039 13.4 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KFX99539.1 - 0.04 14.2 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFX99539.1 - 0.064 12.9 0.0 0.24 11.0 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase TAFII28 PF04719.9 KFX99539.1 - 0.11 12.3 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 1 0 hTAFII28-like protein conserved region Flavi_DEAD PF07652.9 KFX99539.1 - 0.12 12.1 1.0 43 3.8 0.0 3.1 2 1 1 3 3 3 0 Flavivirus DEAD domain XRCC1_N PF01834.11 KFX99540.1 - 0.0088 15.5 1.5 0.064 12.7 0.2 2.3 2 0 0 2 2 2 1 XRCC1 N terminal domain Metallopep PF12044.3 KFX99562.1 - 8.5e-167 554.8 0.0 1.1e-166 554.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KFX99562.1 - 0.00069 19.5 0.2 0.0073 16.1 0.0 2.7 3 1 0 3 3 3 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 KFX99562.1 - 0.03 14.2 0.5 0.055 13.3 0.3 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFX99562.1 - 0.25 11.3 3.8 0.24 11.4 0.9 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Glyco_trans_2_3 PF13632.1 KFX99565.1 - 4.7e-48 163.4 1.3 4.7e-48 163.4 0.9 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KFX99565.1 - 0.028 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sec7 PF01369.15 KFX99566.1 - 9.1e-42 142.8 0.0 3.5e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 KFX99566.1 - 1.9e-20 73.1 0.0 3.9e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Herpes_LMP1 PF05297.6 KFX99566.1 - 1.4 7.7 4.3 3.2 6.5 3.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WH1 PF00568.18 KFX99573.1 - 7e-24 83.6 0.1 1.1e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain CorA PF01544.13 KFX99574.1 - 8.2e-07 28.3 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ERCC4 PF02732.10 KFX99577.1 - 1.7e-24 86.2 0.0 3.6e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Dabb PF07876.7 KFX99578.1 - 5e-11 42.8 0.1 5.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Matrix PF00661.16 KFX99578.1 - 0.11 10.7 0.1 4.3 5.5 0.0 2.0 2 0 0 2 2 2 0 Viral matrix protein Abhydrolase_5 PF12695.2 KFX99580.1 - 4.6e-07 29.6 0.0 6.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX99580.1 - 1.6e-06 28.1 0.1 2.4e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ArsA_ATPase PF02374.10 KFX99581.1 - 6.7e-115 383.3 0.0 7.6e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KFX99581.1 - 1.4e-16 60.5 0.2 2.4e-16 59.7 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFX99581.1 - 1.5e-08 34.7 0.0 6.6e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KFX99581.1 - 4.9e-06 25.9 0.0 8.6e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KFX99581.1 - 6.1e-05 22.5 0.1 0.0023 17.3 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KFX99581.1 - 0.00068 19.0 0.0 0.0024 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX99581.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFX99581.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 KFX99581.1 - 0.028 13.7 0.0 0.065 12.5 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 KFX99581.1 - 0.029 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 KFX99581.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KFX99581.1 - 0.16 12.2 0.1 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Transthyretin PF00576.16 KFX99582.1 - 2.3e-23 82.2 0.2 1.4e-21 76.5 0.1 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family SIR2 PF02146.12 KFX99587.1 - 2.4e-28 99.0 0.0 7.7e-28 97.4 0.0 1.8 1 1 0 1 1 1 1 Sir2 family SOG2 PF10428.4 KFX99587.1 - 6.7 5.2 13.9 1.5 7.4 6.8 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein Med16 PF11635.3 KFX99588.1 - 2.3e-112 376.3 0.0 2.9e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Anoctamin PF04547.7 KFX99589.1 - 0.078 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3268 PF11672.3 KFX99595.1 - 0.017 15.1 0.8 27 4.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3268) MHC_I_C PF06623.6 KFX99595.1 - 0.061 12.8 0.0 7.2 6.1 0.0 2.6 2 0 0 2 2 2 0 MHC_I C-terminus DUF1254 PF06863.7 KFX99595.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1254) Lipoprotein_1 PF00820.14 KFX99595.1 - 0.15 11.1 0.0 13 4.7 0.0 2.0 2 0 0 2 2 2 0 Borrelia lipoprotein zf-RAG1 PF10426.4 KFX99595.1 - 1.2 9.1 11.2 13 5.8 0.3 3.4 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain GFO_IDH_MocA PF01408.17 KFX99596.1 - 1.1e-25 90.4 0.1 2.1e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX99596.1 - 2.2e-11 43.5 0.0 3.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KFX99596.1 - 1.3e-05 25.4 0.1 3.5e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KFX99596.1 - 0.0011 19.3 0.0 0.0038 17.6 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain TB2_DP1_HVA22 PF03134.14 KFX99617.1 - 4.7e-24 83.9 9.3 5.1e-24 83.8 6.5 1.0 1 0 0 1 1 1 1 TB2/DP1, HVA22 family EAF PF09816.4 KFX99626.1 - 8.1e-09 35.4 0.0 9.8e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor FAD_binding_7 PF03441.9 KFX99627.1 - 8.9e-49 166.1 0.1 1.2e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFX99627.1 - 4.3e-20 72.1 0.0 6.8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase PP-binding PF00550.20 KFX99638.1 - 1.2e-25 89.4 4.2 3.9e-12 46.2 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 KFX99638.1 - 5.7e-15 54.9 0.0 1.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_23 PF13489.1 KFX99638.1 - 1.5e-07 31.2 0.0 6.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX99638.1 - 5e-07 30.1 0.0 3.6e-06 27.3 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain adh_short PF00106.20 KFX99638.1 - 9.8e-07 28.8 0.2 4e-06 26.8 0.1 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.1 KFX99638.1 - 1.1e-06 28.2 0.0 2.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX99638.1 - 3.5e-05 24.2 0.2 0.00074 19.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain KR PF08659.5 KFX99638.1 - 4.1e-05 23.3 0.2 0.00015 21.4 0.2 2.0 1 0 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 KFX99638.1 - 5.3e-05 23.7 0.0 0.00036 21.0 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain RrnaAD PF00398.15 KFX99638.1 - 0.0006 18.9 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KFX99638.1 - 0.0015 18.8 0.0 0.0055 17.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFX99638.1 - 0.002 17.7 0.2 0.0071 16.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain YjeF_N PF03853.10 KFX99638.1 - 0.0033 17.0 0.7 3.5 7.1 0.0 3.4 3 0 0 3 3 3 2 YjeF-related protein N-terminus Epimerase PF01370.16 KFX99638.1 - 0.008 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_26 PF13659.1 KFX99638.1 - 0.059 13.4 1.4 0.19 11.7 0.1 2.5 2 0 0 2 2 1 0 Methyltransferase domain DREV PF05219.7 KFX99638.1 - 0.27 10.0 0.0 0.46 9.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AAA PF00004.24 KFX99639.1 - 1.8e-09 37.9 0.9 6.2e-08 32.9 0.6 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KFX99639.1 - 3e-05 22.8 1.1 0.001 17.8 0.0 2.8 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KFX99639.1 - 0.00016 22.4 0.0 0.00048 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX99639.1 - 0.00071 19.7 0.1 0.0033 17.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX99639.1 - 0.0019 18.2 0.1 0.0067 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KFX99639.1 - 0.0096 15.6 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 KFX99639.1 - 0.014 15.3 0.0 0.082 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 KFX99639.1 - 0.038 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX99639.1 - 0.063 13.1 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KFX99639.1 - 0.075 11.7 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KFX99639.1 - 0.087 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KFX99639.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RuvB_N PF05496.7 KFX99639.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Utp8 PF10395.4 KFX99640.1 - 2.5e-05 22.8 2.9 0.02 13.2 1.1 2.5 2 1 0 2 2 2 2 Utp8 family DNA_binding_1 PF01035.15 KFX99642.1 - 3.2e-23 81.2 0.0 3.9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.11 KFX99643.1 - 3.5e-30 103.3 3.2 5.6e-30 102.7 2.2 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KFX99643.1 - 3.3e-07 29.9 0.0 8.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KFX99643.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-synt_F PF01990.12 KFX99660.1 - 3.9e-32 110.4 0.1 4.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 KFX99661.1 - 3.1e-25 88.9 0.2 3.6e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KFX99661.1 - 0.0028 17.7 0.1 0.0064 16.5 0.1 1.6 1 1 0 1 1 1 1 ML-like domain NPCBM_assoc PF10633.4 KFX99661.1 - 0.053 13.5 0.2 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Alph_Pro_TM PF09608.5 KFX99661.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Arf PF00025.16 KFX99666.1 - 2.6e-44 150.5 0.0 3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFX99666.1 - 1.1e-18 67.0 0.0 1.3e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX99666.1 - 3.2e-10 40.5 0.0 5.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFX99666.1 - 3.3e-08 32.9 0.0 3.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX99666.1 - 9.2e-06 24.9 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX99666.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFX99666.1 - 8.8e-05 21.3 0.2 0.00019 20.2 0.1 1.5 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFX99666.1 - 0.0001 21.8 0.0 0.0026 17.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFX99666.1 - 0.01 15.6 0.0 0.075 12.8 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 KFX99666.1 - 0.013 14.7 0.1 0.071 12.3 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KFX99666.1 - 0.037 13.5 0.1 0.32 10.4 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KFX99666.1 - 0.11 12.1 0.4 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RCR PF12273.3 KFX99667.1 - 2.3e-24 86.4 6.4 3.4e-24 85.8 4.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.13 KFX99667.1 - 0.0086 14.3 0.3 0.011 13.9 0.2 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Shisa PF13908.1 KFX99667.1 - 0.08 13.1 1.9 0.35 11.0 1.3 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator WBP-1 PF11669.3 KFX99667.1 - 0.67 10.0 3.3 0.4 10.7 0.4 2.0 1 1 1 2 2 2 0 WW domain-binding protein 1 Corona_S2 PF01601.11 KFX99668.1 - 0.0015 16.7 12.9 0.0019 16.4 8.9 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Prominin PF05478.6 KFX99668.1 - 1.1 6.7 12.6 1.5 6.2 8.8 1.1 1 0 0 1 1 1 0 Prominin VSP PF03302.8 KFX99669.1 - 0.055 12.1 0.4 0.084 11.4 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Mid2 PF04478.7 KFX99669.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 KFX99669.1 - 0.17 10.1 0.1 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Glyco_hydro_43 PF04616.9 KFX99677.1 - 5.2e-10 38.8 2.1 8.9e-10 38.1 1.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RTC4 PF14474.1 KFX99678.1 - 8.8e-27 93.5 0.0 1.4e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain ADIP PF11559.3 KFX99681.1 - 5.1e-31 107.6 0.4 5.6e-31 107.4 0.2 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HAP1_N PF04849.8 KFX99681.1 - 0.0065 15.4 0.5 0.008 15.1 0.3 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.3 KFX99681.1 - 0.029 14.1 1.4 0.029 14.1 1.0 1.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FAD_binding_8 PF08022.7 KFX99683.1 - 1.7e-17 63.2 0.0 4.2e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFX99683.1 - 5.2e-14 52.4 12.8 5.2e-14 52.4 8.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX99683.1 - 1.5e-06 28.2 3.5 4.4e-06 26.6 2.4 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KFX99683.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain IGPD PF00475.13 KFX99692.1 - 1e-59 200.5 0.2 1.6e-59 199.8 0.1 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.6 KFX99694.1 - 2.1e-20 72.5 0.1 4.9e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFX99694.1 - 5.1e-12 45.7 0.0 4.4e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFX99694.1 - 3.6e-11 43.3 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFX99694.1 - 6.9e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX99694.1 - 1.1e-05 25.5 0.1 0.0028 17.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX99694.1 - 1.5e-05 25.1 0.1 0.00038 20.5 0.0 2.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KFX99694.1 - 4.3e-05 23.0 0.0 0.0086 15.5 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain Viral_helicase1 PF01443.13 KFX99694.1 - 8e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 KFX99694.1 - 9.3e-05 21.5 0.0 0.00022 20.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KFX99694.1 - 0.00014 20.6 0.0 0.0087 14.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 KFX99694.1 - 0.00033 20.2 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX99694.1 - 0.0022 17.6 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KFX99694.1 - 0.0023 17.1 0.1 0.032 13.3 0.0 2.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KFX99694.1 - 0.0026 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DEAD PF00270.24 KFX99694.1 - 0.0026 17.2 0.1 0.11 11.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 KFX99694.1 - 0.0059 16.3 0.1 0.051 13.2 0.0 2.3 1 1 0 2 2 2 1 NTPase ArgK PF03308.11 KFX99694.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_31 PF13614.1 KFX99694.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KFX99694.1 - 0.013 15.0 0.1 0.029 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX99694.1 - 0.018 14.4 0.1 0.078 12.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain DNA_pol3_delta PF06144.8 KFX99694.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit KTI12 PF08433.5 KFX99694.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 KFX99694.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KFX99694.1 - 0.088 12.9 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KFX99694.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Asp PF00026.18 KFX99695.1 - 2.8e-73 246.9 2.4 3.4e-73 246.6 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX99695.1 - 1e-10 41.7 0.0 4.5e-10 39.7 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFX99695.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFX99695.1 - 0.00087 19.7 0.3 4.3 7.9 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease AAA PF00004.24 KFX99696.1 - 5e-19 68.8 0.0 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX99696.1 - 0.00073 19.6 0.3 0.026 14.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFX99696.1 - 0.0023 17.8 0.1 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFX99696.1 - 0.0055 17.5 0.4 0.079 13.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX99696.1 - 0.0063 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KFX99696.1 - 0.02 14.6 0.1 0.059 13.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFX99696.1 - 0.025 14.3 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KFX99696.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DAO PF01266.19 KFX99697.1 - 2.1e-36 125.5 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX99697.1 - 4.5e-05 23.3 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX99697.1 - 0.00026 20.9 0.1 0.0076 16.1 0.0 2.8 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX99697.1 - 0.0028 17.4 0.0 0.0085 15.9 0.0 1.8 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFX99697.1 - 0.0039 17.2 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KFX99697.1 - 0.0071 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFX99697.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX99697.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KFX99697.1 - 0.033 13.0 0.1 2.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFX99697.1 - 0.13 11.0 0.1 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 KFX99697.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KFX99698.1 - 1.3e-60 205.2 24.7 1.9e-60 204.7 17.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 KFX99698.1 - 1.1e-29 103.0 0.8 1.6e-29 102.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX99698.1 - 1.5e-20 73.2 37.3 1e-18 67.1 13.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KFX99698.1 - 1.5e-09 37.5 7.5 3.1e-09 36.5 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 KFX99698.1 - 0.28 10.8 0.4 1.2 8.8 0.3 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension LysM PF01476.15 KFX99699.1 - 9.3e-12 44.6 0.2 0.00024 20.9 0.1 2.8 3 0 0 3 3 3 2 LysM domain DUF1020 PF06255.8 KFX99699.1 - 0.19 10.9 0.3 18 4.3 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1020) Atrophin-1 PF03154.10 KFX99699.1 - 2.2 6.3 5.5 3.4 5.6 3.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family Ifi-6-16 PF06140.8 KFX99702.1 - 0.0029 17.3 16.4 0.0029 17.3 11.4 2.7 2 1 0 2 2 2 2 Interferon-induced 6-16 family Cut12 PF11500.3 KFX99703.1 - 9.5e-38 129.2 11.4 9.5e-38 129.2 7.9 3.8 2 2 0 2 2 2 1 Spindle pole body formation-associated protein UQ_con PF00179.21 KFX99703.1 - 1.4e-37 128.2 0.0 2.9e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IncA PF04156.9 KFX99703.1 - 4.3 6.8 34.5 7.3 6.1 15.8 2.9 1 1 2 3 3 3 0 IncA protein Mad3_BUB1_II PF08171.6 KFX99704.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Histone PF00125.19 KFX99705.1 - 1e-28 99.2 0.3 1.7e-28 98.5 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFX99705.1 - 9.7e-06 25.6 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX99705.1 - 0.006 16.6 0.1 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KFX99705.1 - 0.0062 15.8 0.4 0.0084 15.3 0.3 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T DER1 PF04511.10 KFX99706.1 - 1.8e-53 180.9 5.0 2.3e-53 180.6 3.5 1.0 1 0 0 1 1 1 1 Der1-like family PNRC PF15365.1 KFX99707.1 - 1.6e-06 28.0 3.4 1.6e-06 28.0 2.4 4.4 6 0 0 6 6 6 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 KFX99708.1 - 1.3e-35 121.2 13.7 1.6e-35 121.0 9.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFX99708.1 - 3.7e-17 61.9 10.0 5e-17 61.5 6.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFX99708.1 - 2.2e-07 30.6 12.1 1.3e-06 28.0 8.4 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX99708.1 - 0.0015 18.1 11.8 0.024 14.3 8.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX99708.1 - 0.0026 17.4 9.5 0.26 10.9 6.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX99708.1 - 0.04 13.9 12.7 0.043 13.8 5.6 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFX99708.1 - 0.55 10.2 9.3 2.7 8.0 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 KFX99708.1 - 0.77 9.5 11.7 6.8 6.5 8.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFX99708.1 - 1.1 8.9 7.1 23 4.7 4.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 KFX99708.1 - 2.5 8.2 10.7 1.2e+02 2.8 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain SPC12 PF06645.8 KFX99709.1 - 1.1e-27 95.6 0.1 1.3e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 KFX99709.1 - 0.0081 16.5 0.2 0.0086 16.4 0.1 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein FAD_binding_4 PF01565.18 KFX99709.1 - 0.046 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3040 PF11239.3 KFX99709.1 - 0.16 12.0 2.6 0.23 11.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MS_channel PF00924.13 KFX99709.1 - 0.54 9.5 4.5 0.93 8.7 3.1 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel CorA PF01544.13 KFX99710.1 - 1.3e-44 152.4 0.2 1.8e-44 151.9 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 KFX99711.1 - 9.9e-24 82.4 2.0 1.3e-23 82.0 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.8 KFX99712.1 - 9.5e-22 76.7 7.8 2.2e-21 75.6 5.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KFX99712.1 - 2.4e-16 59.4 1.5 5.1e-16 58.3 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 P2 PF07194.6 KFX99712.1 - 0.09 12.6 0.6 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain DUF3321 PF11968.3 KFX99713.1 - 6.7e-89 297.2 0.0 8.2e-89 296.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KFX99713.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Aa_trans PF01490.13 KFX99714.1 - 1.3e-60 205.0 26.0 1.6e-60 204.7 18.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.10 KFX99715.1 - 2.3e-46 157.3 0.4 5.7e-46 156.1 0.1 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 KFX99715.1 - 1e-39 135.2 0.9 2.1e-39 134.2 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KFX99715.1 - 3.2e-28 97.9 0.0 6.7e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KFX99715.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PDT PF00800.13 KFX99716.1 - 2.9e-66 222.5 0.0 7.5e-66 221.1 0.0 1.7 2 0 0 2 2 2 1 Prephenate dehydratase MaoC_dehydratas PF01575.14 KFX99716.1 - 7.8e-06 25.2 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Pterin_bind PF00809.17 KFX99716.1 - 0.096 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Pterin binding enzyme HAUS6_N PF14661.1 KFX99726.1 - 0.0025 17.2 13.4 0.003 16.9 9.3 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Peptidase_C50 PF03568.12 KFX99726.1 - 0.23 10.0 9.5 0.28 9.8 6.6 1.1 1 0 0 1 1 1 0 Peptidase family C50 CAF-1_p150 PF11600.3 KFX99726.1 - 0.47 9.8 31.0 0.5 9.6 21.5 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 KFX99726.1 - 0.47 8.4 11.5 0.53 8.3 8.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FLO_LFY PF01698.11 KFX99726.1 - 0.47 9.2 12.6 0.53 9.0 8.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TEX19 PF15553.1 KFX99726.1 - 0.64 9.8 4.0 0.75 9.6 2.8 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF342 PF03961.8 KFX99726.1 - 0.9 7.8 14.0 1.1 7.6 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1510 PF07423.6 KFX99726.1 - 1.3 8.3 15.7 1.4 8.2 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AAA_11 PF13086.1 KFX99726.1 - 1.4 8.3 12.2 1.7 8.1 8.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.1 KFX99726.1 - 1.5 8.5 19.9 2.5 7.8 13.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1943 PF09172.6 KFX99726.1 - 1.6 7.5 8.1 1.9 7.3 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Folate_carrier PF01770.13 KFX99726.1 - 1.9 6.9 5.7 1.9 6.9 3.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier APG6 PF04111.7 KFX99726.1 - 2 7.3 16.1 2.3 7.1 11.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF853 PF05872.7 KFX99726.1 - 2.1 6.6 6.4 2.3 6.4 4.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_23 PF13476.1 KFX99726.1 - 2.3 8.5 14.4 2.8 8.2 10.0 1.1 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.5 KFX99726.1 - 2.4 8.1 20.5 2.7 7.9 14.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2151 PF10221.4 KFX99726.1 - 2.6 6.0 13.4 3 5.8 9.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator GAGA_bind PF06217.7 KFX99726.1 - 3 7.7 14.4 3.5 7.5 10.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3807 PF12720.2 KFX99726.1 - 3.2 7.8 15.7 3.8 7.6 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SPATIAL PF15256.1 KFX99726.1 - 3.3 7.7 9.2 3.8 7.5 6.4 1.0 1 0 0 1 1 1 0 SPATIAL Vma12 PF11712.3 KFX99726.1 - 3.3 7.4 7.2 4.4 7.0 5.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Paramyxo_ncap PF00973.14 KFX99726.1 - 3.9 6.0 7.4 4.1 5.9 5.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Borrelia_P83 PF05262.6 KFX99726.1 - 4.7 5.3 20.0 5.3 5.2 13.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec62 PF03839.11 KFX99726.1 - 4.9 6.5 16.6 5.5 6.3 11.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3987 PF13148.1 KFX99726.1 - 5.2 5.5 16.8 6.3 5.2 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CT47 PF15623.1 KFX99726.1 - 6.3 6.4 15.3 6.9 6.3 10.6 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Peptidase_U57 PF05582.7 KFX99726.1 - 7.2 5.4 9.7 8.3 5.2 6.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Mitofilin PF09731.4 KFX99726.1 - 7.8 5.0 18.0 11 4.5 12.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein OmpH PF03938.9 KFX99726.1 - 8.4 6.3 25.9 5.8 6.8 16.9 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DDHD PF02862.12 KFX99726.1 - 9.1 6.0 10.2 10 5.8 7.1 1.1 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 KFX99726.1 - 9.3 5.3 17.6 11 5.1 12.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF106 PF01956.11 KFX99726.1 - 9.3 5.7 15.0 12 5.3 10.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 ARD PF03079.9 KFX99726.1 - 9.6 6.1 11.2 13 5.6 7.7 1.3 1 0 0 1 1 1 0 ARD/ARD' family CAF-1_p150 PF11600.3 KFX99727.1 - 0.01 15.1 5.2 0.014 14.7 3.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CCDC-167 PF15188.1 KFX99727.1 - 0.14 12.1 2.8 0.17 11.8 1.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Afaf PF15339.1 KFX99727.1 - 0.45 10.0 2.3 5.9 6.4 0.2 2.1 2 0 0 2 2 2 0 Acrosome formation-associated factor DUF2839 PF10999.3 KFX99727.1 - 1.3 9.0 5.4 0.71 9.9 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2839) CALCOCO1 PF07888.6 KFX99728.1 - 0.018 13.3 1.1 0.019 13.2 0.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Self-incomp_S1 PF05938.6 KFX99728.1 - 0.029 14.4 2.3 0.043 13.9 1.6 1.3 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 Myc_target_1 PF15179.1 KFX99731.1 - 0.83 9.2 3.8 0.62 9.6 0.2 2.0 2 0 0 2 2 2 0 Myc target protein 1 CDC45 PF02724.9 KFX99731.1 - 5.2 4.9 10.9 6.2 4.7 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Cation_efflux PF01545.16 KFX99733.1 - 0.00017 20.7 11.6 0.0024 17.0 8.0 2.0 1 1 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.16 KFX99734.1 - 1e-33 116.6 7.1 1.2e-33 116.4 4.9 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3483 PF11982.3 KFX99734.1 - 0.0034 16.6 1.5 0.0044 16.3 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) DUF2776 PF10951.3 KFX99734.1 - 0.0081 15.2 0.2 0.0081 15.2 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2776) DUF3185 PF11381.3 KFX99734.1 - 0.14 11.9 2.8 0.61 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2407_C PF13373.1 KFX99734.1 - 0.67 9.8 3.1 7.2 6.5 0.1 2.7 2 1 1 3 3 3 0 DUF2407 C-terminal domain Antimicrobial10 PF08105.6 KFX99739.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Metchnikowin family RINGv PF12906.2 KFX99744.1 - 3.4e-09 36.5 3.6 6.7e-09 35.6 0.5 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KFX99744.1 - 0.023 14.5 1.5 0.023 14.5 1.1 2.1 2 0 0 2 2 2 0 Ring finger domain Xan_ur_permease PF00860.15 KFX99744.1 - 0.081 11.3 0.3 0.29 9.5 0.0 1.8 2 0 0 2 2 2 0 Permease family Proteasome PF00227.21 KFX99745.1 - 5.9e-57 192.0 0.0 6.1e-33 113.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFX99745.1 - 1.7e-11 43.2 0.4 3.5e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MSC PF09402.5 KFX99746.1 - 0.12 11.0 0.0 0.24 10.0 0.0 1.5 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain 3HCDH_N PF02737.13 KFX99749.1 - 6.4e-32 110.6 0.0 8.8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFX99749.1 - 1.9e-17 63.4 0.0 3.2e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KFX99749.1 - 0.00041 20.1 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KFX99749.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KFX99749.1 - 0.015 14.7 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_1 PF00175.16 KFX99750.1 - 4.7e-30 104.3 0.0 8.8e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFX99750.1 - 5.5e-28 96.9 0.0 1e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KFX99750.1 - 6.1e-23 80.4 0.0 1.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFX99750.1 - 0.0017 18.3 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFX99750.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain p450 PF00067.17 KFX99751.1 - 1.3e-58 198.6 0.0 1.6e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KFX99752.1 - 1.9e-29 101.9 0.7 3.3e-29 101.1 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX99752.1 - 8.1e-11 41.6 0.0 1.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HK PF02110.10 KFX99753.1 - 4.4e-76 255.2 0.3 6.4e-76 254.7 0.2 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KFX99753.1 - 6e-56 188.3 1.2 1e-55 187.6 0.8 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KFX99753.1 - 7.3e-07 28.7 0.3 3.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KFX99753.1 - 0.0033 16.6 1.1 0.041 13.0 0.0 2.6 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase Peripla_BP_6 PF13458.1 KFX99753.1 - 0.0049 16.2 0.3 0.67 9.2 0.0 3.3 3 1 1 4 4 4 1 Periplasmic binding protein chaperone_DMP PF10448.4 KFX99753.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 20S proteasome chaperone LPP20 PF02169.11 KFX99760.1 - 0.042 13.9 0.6 0.053 13.6 0.4 1.1 1 0 0 1 1 1 0 LPP20 lipoprotein Sad1_UNC PF07738.8 KFX99762.1 - 9.5e-10 38.3 0.0 9e-08 31.9 0.0 2.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Scaffolding_pro PF11418.3 KFX99762.1 - 0.015 15.5 0.3 0.028 14.7 0.2 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein MreB_Mbl PF06723.8 KFX99776.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein ETF PF01012.16 KFX99777.1 - 2.9e-36 124.6 0.1 3.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Lipoprotein_3 PF00938.12 KFX99777.1 - 0.019 14.7 0.2 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein Cyclin_N PF00134.18 KFX99778.1 - 1.7e-05 24.3 0.1 0.0057 16.2 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 KFX99778.1 - 0.00017 21.3 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Reprolysin_5 PF13688.1 KFX99779.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 FSH1 PF03959.8 KFX99780.1 - 1.6e-31 109.4 0.0 4.3e-31 108.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFX99780.1 - 2.8e-05 24.1 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhrC_PhrF PF11131.3 KFX99781.1 - 0.043 13.3 0.5 0.078 12.5 0.3 1.4 1 0 0 1 1 1 0 Rap-phr extracellular signalling CaKB PF03185.10 KFX99781.1 - 0.043 13.1 0.6 0.045 13.1 0.4 1.1 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Sec63 PF02889.11 KFX99782.1 - 2.5e-143 476.9 0.0 8.6e-90 301.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KFX99782.1 - 2e-52 177.0 0.2 4.2e-28 97.9 0.3 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX99782.1 - 3.5e-16 58.8 0.0 9.8e-07 28.5 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFX99782.1 - 1e-13 51.5 0.0 6e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFX99782.1 - 2e-07 31.2 0.5 0.049 13.7 0.0 3.9 4 2 0 4 4 3 2 AAA domain AAA_19 PF13245.1 KFX99782.1 - 7.4e-07 28.8 0.2 0.012 15.3 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KFX99782.1 - 0.0002 21.5 0.0 1.6 8.8 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KFX99782.1 - 0.0004 19.2 0.0 0.043 12.6 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain IstB_IS21 PF01695.12 KFX99782.1 - 0.0024 17.3 0.3 5.5 6.3 0.0 3.4 4 0 0 4 4 4 2 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KFX99782.1 - 0.0055 16.2 0.1 0.53 9.7 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFX99782.1 - 0.011 15.1 0.0 4.2 6.7 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain PhoH PF02562.11 KFX99782.1 - 0.018 14.2 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein GAD-like PF08887.6 KFX99782.1 - 0.047 13.7 0.0 0.65 10.0 0.0 2.5 2 0 0 2 2 2 0 GAD-like domain Synaptobrevin PF00957.16 KFX99783.1 - 1.3e-13 50.3 0.5 2.6e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KFX99783.1 - 3.1e-12 45.8 0.0 6.3e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain YueH PF14166.1 KFX99783.1 - 0.058 13.1 0.2 0.68 9.7 0.0 2.4 2 0 0 2 2 2 0 YueH-like protein DUF3755 PF12579.3 KFX99783.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) FMN_dh PF01070.13 KFX99784.1 - 4.1e-121 404.1 0.1 5e-121 403.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFX99784.1 - 1.7e-22 79.0 0.0 3.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KFX99784.1 - 5.3e-09 35.4 0.1 9e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFX99784.1 - 0.00078 18.4 0.2 0.0018 17.2 0.1 1.7 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KFX99784.1 - 0.033 13.4 0.5 1.5 8.0 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 KFX99784.1 - 0.037 13.1 1.2 0.65 9.0 0.1 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG HMGL-like PF00682.14 KFX99785.1 - 2.3e-70 236.9 0.1 4.3e-70 236.0 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Glyco_hydro_61 PF03443.9 KFX99786.1 - 2.4e-50 171.3 0.0 2.6e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cadherin_pro PF08758.6 KFX99786.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Cadherin prodomain like DUF1751 PF08551.5 KFX99788.1 - 2.1e-22 79.3 4.1 3.1e-22 78.7 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KFX99788.1 - 0.39 10.7 5.5 0.079 12.9 1.6 1.4 2 0 0 2 2 2 0 Rhomboid family WD40 PF00400.27 KFX99789.1 - 3.1e-18 64.8 6.2 7.4e-06 25.6 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat LisH PF08513.6 KFX99789.1 - 2.5e-08 33.4 0.1 4.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 LisH PD40 PF07676.7 KFX99789.1 - 0.02 14.5 0.6 16 5.2 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KFX99789.1 - 0.1 10.3 0.0 0.67 7.6 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Peptidase_M24 PF00557.19 KFX99790.1 - 2.6e-43 148.0 0.0 3.4e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.7 KFX99790.1 - 0.21 11.3 1.6 0.43 10.3 1.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Stc1 PF12898.2 KFX99801.1 - 6.1e-16 58.2 11.2 1.1e-15 57.4 7.8 1.4 1 0 0 1 1 1 1 Stc1 domain NYD-SP28_assoc PF14775.1 KFX99807.1 - 0.021 14.5 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_1 PF00170.16 KFX99807.1 - 3.7 7.5 9.3 0.89 9.5 3.5 2.0 1 1 1 2 2 2 0 bZIP transcription factor DUF2417 PF10329.4 KFX99808.1 - 4.3e-38 131.0 0.2 7.3e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KFX99808.1 - 3.1e-07 30.5 0.4 7.3e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pkinase PF00069.20 KFX99808.1 - 0.1 11.7 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain HMG_box PF00505.14 KFX99809.1 - 2.3e-11 43.7 0.2 7.4e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.25 KFX99809.1 - 5.5e-11 42.4 0.0 9.4e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 KFX99809.1 - 1.1e-10 41.6 0.0 3.3e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.12 KFX99809.1 - 7.7e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Choline_kinase PF01633.15 KFX99820.1 - 0.22 11.0 0.1 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tetraspannin PF00335.15 KFX99821.1 - 4.6e-06 26.0 0.5 1.2e-05 24.6 0.4 1.7 1 1 0 1 1 1 1 Tetraspanin family ARL6IP6 PF15062.1 KFX99821.1 - 0.081 12.8 0.0 9.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Xan_ur_permease PF00860.15 KFX99822.1 - 1e-21 76.9 32.3 5.1e-21 74.6 22.4 2.2 1 1 0 1 1 1 1 Permease family QRPTase_C PF01729.14 KFX99823.1 - 2.4e-56 189.8 0.1 3.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KFX99823.1 - 7.2e-20 70.5 0.0 2.5e-19 68.8 0.0 1.9 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 KFX99823.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF1341 PF07071.6 KFX99823.1 - 0.13 11.7 0.1 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1341) ADH_N PF08240.7 KFX99824.1 - 4e-11 42.6 0.0 8.5e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX99824.1 - 3.3e-07 29.9 1.3 7.2e-07 28.8 0.9 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KFX99824.1 - 1.5 8.6 5.2 0.29 10.9 0.6 2.2 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3237 PF11578.3 KFX99825.1 - 3e-22 78.5 0.0 4.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF4470 PF14737.1 KFX99826.1 - 5.8e-25 86.9 0.1 1.3e-24 85.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Ank_2 PF12796.2 KFX99832.1 - 4.9e-41 138.9 8.8 7e-13 48.7 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX99832.1 - 4.3e-28 95.7 7.2 9e-05 22.0 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFX99832.1 - 1.8e-25 88.8 0.8 1.4e-07 31.8 0.0 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX99832.1 - 1.3e-23 82.4 2.8 4.8e-07 29.8 0.1 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99832.1 - 3e-22 76.4 3.5 0.024 14.8 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat NACHT PF05729.7 KFX99832.1 - 1.2e-07 31.5 0.0 9.9e-07 28.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFX99832.1 - 7.8e-07 29.2 0.0 3.6e-06 27.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX99832.1 - 0.04 14.0 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain APC8 PF04049.8 KFX99834.1 - 1.6e-32 112.2 0.1 5.5e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 KFX99834.1 - 8.9e-25 86.1 14.3 6.1e-09 35.4 1.0 5.7 3 1 3 6 6 6 4 TPR repeat TPR_1 PF00515.23 KFX99834.1 - 8.6e-23 78.9 6.9 7.6e-05 22.1 0.1 6.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFX99834.1 - 2.8e-18 64.3 12.6 0.0049 16.6 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX99834.1 - 1.5e-13 50.0 18.1 0.032 14.8 0.1 9.7 8 2 3 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFX99834.1 - 4.9e-11 41.5 5.2 0.0011 18.6 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX99834.1 - 3.1e-10 39.4 4.3 0.27 11.5 0.0 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX99834.1 - 4.6e-10 39.8 7.6 0.0071 17.0 0.1 6.1 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX99834.1 - 6.1e-10 38.8 16.1 1.6e-05 24.7 1.5 6.7 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 KFX99834.1 - 3.4e-09 36.4 6.2 0.003 17.3 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX99834.1 - 4e-09 35.5 13.5 0.074 12.8 0.1 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 KFX99834.1 - 9e-09 35.3 7.4 0.041 14.0 0.0 6.1 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFX99834.1 - 2.5e-06 27.7 13.4 0.0084 16.4 0.0 6.1 4 2 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX99834.1 - 0.00074 19.8 9.3 0.96 10.0 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 KFX99834.1 - 0.0089 15.8 0.6 0.1 12.3 0.1 2.7 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) DUF4075 PF13294.1 KFX99834.1 - 0.23 11.5 0.8 0.74 9.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) Pkinase PF00069.20 KFX99836.1 - 2.3e-43 148.2 0.0 2.4e-42 144.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99836.1 - 2.5e-25 89.0 0.0 7.5e-25 87.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase WH2 PF02205.15 KFX99843.1 - 7e-06 25.4 0.6 1.7e-05 24.2 0.4 1.7 1 0 0 1 1 1 1 WH2 motif eIF-1a PF01176.14 KFX99844.1 - 4.4e-28 96.4 0.0 6.2e-28 96.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 KFX99846.1 - 3.2e-11 42.9 0.0 6.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFX99846.1 - 4.1e-08 33.2 0.0 8.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KFX99846.1 - 0.00076 19.5 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KFX99846.1 - 0.0034 17.1 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) adh_short PF00106.20 KFX99847.1 - 3.9e-06 26.8 0.0 7.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99847.1 - 0.00032 20.4 0.0 0.00062 19.4 0.0 1.5 2 0 0 2 2 2 1 KR domain CBM_6 PF03422.10 KFX99847.1 - 0.05 13.7 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SEN1_N PF12726.2 KFX99848.1 - 1.1e-182 608.8 1.4 1.4e-182 608.5 1.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KFX99848.1 - 1.6e-66 224.2 0.3 1.6e-66 224.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KFX99848.1 - 5.7e-59 198.8 0.0 1.1e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX99848.1 - 2.2e-10 40.1 0.1 7.1e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFX99848.1 - 1e-06 28.4 0.0 0.00065 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 KFX99848.1 - 1.2e-06 28.0 0.0 0.00028 20.3 0.0 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KFX99848.1 - 2.3e-06 27.3 1.1 0.077 12.5 0.0 4.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KFX99848.1 - 0.0076 15.7 0.1 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Hydrolase PF00702.21 KFX99849.1 - 1.3e-13 51.9 3.5 6.5e-12 46.3 2.4 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX99849.1 - 2.5e-12 47.3 0.0 6.6e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX99849.1 - 7.4e-12 45.0 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KFX99849.1 - 1.1e-11 44.2 0.0 1.1e-11 44.2 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KFX99849.1 - 0.018 14.5 0.4 0.056 13.0 0.3 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAM178 PF14816.1 KFX99850.1 - 0.00022 20.0 0.2 0.00042 19.1 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function, FAM178 vATP-synt_E PF01991.13 KFX99851.1 - 1.6e-59 200.5 10.1 1.9e-59 200.3 7.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NMD3 PF04981.8 KFX99851.1 - 0.43 9.6 7.5 1.1 8.2 2.9 2.1 2 0 0 2 2 2 0 NMD3 family NusB PF01029.13 KFX99851.1 - 0.44 10.5 4.5 0.21 11.5 0.5 2.2 2 1 0 2 2 2 0 NusB family FCH PF00611.18 KFX99853.1 - 4.1e-13 49.3 0.1 1.2e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RGCC PF15151.1 KFX99853.1 - 0.022 15.1 0.5 0.063 13.7 0.1 1.8 1 1 0 1 1 1 0 Response gene to complement 32 protein family Ras PF00071.17 KFX99855.1 - 9.9e-54 181.0 0.0 1.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX99855.1 - 7.8e-18 65.0 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX99855.1 - 7.2e-07 28.6 0.0 9.5e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Mur_ligase_C PF02875.16 KFX99855.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RRM_1 PF00076.17 KFX99856.1 - 2.3e-10 39.9 0.0 5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX99856.1 - 3.4e-10 39.7 0.0 6.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX99856.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 KFX99857.1 - 2.7e-94 314.9 4.6 3.1e-94 314.7 3.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 KFX99857.1 - 0.00033 20.1 0.0 0.00047 19.6 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3408 PF11888.3 KFX99857.1 - 1.7 8.5 5.6 4 7.3 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) CENP-T PF15511.1 KFX99858.1 - 2.9e-100 336.4 32.0 2.2e-99 333.5 12.8 2.1 2 0 0 2 2 2 2 Centromere kinetochore component CENP-T CENP-S PF15630.1 KFX99858.1 - 7.7e-09 35.6 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX99858.1 - 4.2e-06 26.7 0.0 9.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX99858.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SURF1 PF02104.10 KFX99859.1 - 9.6e-65 218.3 0.0 1.2e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 KFX99860.1 - 2.1e-12 46.8 0.0 4.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain HNF-1_N PF04814.8 KFX99860.1 - 0.021 14.9 2.3 0.045 13.8 1.6 1.6 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CAF-1_p150 PF11600.3 KFX99860.1 - 0.11 11.8 24.0 0.19 11.0 16.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 KFX99860.1 - 0.28 11.5 2.0 0.41 10.9 1.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.5 KFX99860.1 - 0.44 9.7 17.7 0.68 9.0 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1510 PF07423.6 KFX99860.1 - 0.9 8.8 10.4 1.5 8.1 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2076 PF09849.4 KFX99861.1 - 1.9e-08 34.6 9.2 2.2e-08 34.4 6.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KFX99861.1 - 0.00013 21.7 6.5 0.00018 21.3 4.5 1.2 1 0 0 1 1 1 1 CHCH domain Sas10_Utp3 PF04000.10 KFX99862.1 - 4e-17 62.1 0.1 4e-17 62.1 0.1 2.2 2 1 0 2 2 2 1 Sas10/Utp3/C1D family RR_TM4-6 PF06459.7 KFX99862.1 - 0.23 11.2 17.5 0.29 11.0 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 KFX99862.1 - 4.8 4.7 14.5 5.6 4.5 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3275 PF11679.3 KFX99862.1 - 6.8 6.2 7.7 11 5.6 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) dsDNA_bind PF01984.15 KFX99863.1 - 1.4e-33 115.0 5.8 3.1e-33 113.9 4.0 1.6 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ApbA_C PF08546.6 KFX99863.1 - 1.1e-20 73.8 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFX99863.1 - 2.4e-16 59.5 0.0 4.9e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CD99L2 PF12301.3 KFX99863.1 - 0.021 14.5 0.6 0.021 14.5 0.4 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 Coq4 PF05019.8 KFX99864.1 - 2.1e-97 324.4 0.0 2.4e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 KFX99865.1 - 1.3e-14 54.8 0.0 2.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF21 PF01595.15 KFX99866.1 - 8.2e-23 80.6 4.5 1.3e-22 79.9 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 RRM_6 PF14259.1 KFX99866.1 - 7.3e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX99866.1 - 0.00096 18.7 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX99866.1 - 0.0027 17.5 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.15 KFX99867.1 - 1e-12 47.4 0.0 1.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 KFX99868.1 - 3.5e-23 80.5 12.2 1e-08 34.7 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Myb_DNA-binding PF00249.26 KFX99869.1 - 7e-18 64.4 0.7 2.2e-09 37.2 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX99869.1 - 3.7e-14 52.5 0.1 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Semialdhyde_dhC PF02774.13 KFX99870.1 - 1.7e-38 132.2 0.1 2.3e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KFX99870.1 - 4.2e-29 101.3 0.0 2.6e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX99870.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KFX99870.1 - 0.029 13.3 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 KFX99870.1 - 0.038 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SAICAR_synt PF01259.13 KFX99871.1 - 2.3e-85 285.6 0.0 2.8e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Ribosomal_S4e PF00900.15 KFX99872.1 - 5.6e-32 109.2 0.2 1.1e-31 108.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KFX99872.1 - 1.2e-18 66.6 4.9 2.3e-18 65.7 3.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KFX99872.1 - 6e-07 28.8 0.0 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KFX99872.1 - 0.0018 17.8 3.9 0.0028 17.3 0.4 3.0 3 0 0 3 3 3 1 KOW motif FAD-oxidase_C PF02913.14 KFX99873.1 - 6.2e-61 205.8 0.1 8.9e-61 205.3 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFX99873.1 - 2.1e-33 114.7 0.0 4e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KFX99873.1 - 0.0026 16.2 0.0 0.0049 15.3 0.0 1.4 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RdRP PF05183.7 KFX99874.1 - 5.9e-183 609.6 0.1 8.1e-183 609.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3942 PF13078.1 KFX99874.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) RRM_1 PF00076.17 KFX99874.1 - 0.082 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.14 KFX99891.1 - 4.7e-25 88.4 1.0 8.5e-25 87.5 0.7 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFX99891.1 - 4.7e-15 55.5 0.0 1.1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif GET2 PF08690.5 KFX99892.1 - 3.6e-08 33.0 0.5 8.5e-08 31.7 0.3 1.7 1 1 0 1 1 1 1 GET complex subunit GET2 FXR1P_C PF12235.3 KFX99892.1 - 0.2 11.7 2.0 11 6.1 0.5 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal Abhydrolase_3 PF07859.8 KFX99893.1 - 1.8e-36 125.6 0.0 3.2e-25 88.9 0.0 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX99893.1 - 0.0094 14.6 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) LIM_bind PF01803.11 KFX99894.1 - 1.7e-79 266.3 0.4 1.7e-79 266.3 0.3 5.2 2 1 2 5 5 5 1 LIM-domain binding protein Vps39_1 PF10366.4 KFX99895.1 - 6.1e-35 119.4 0.0 5.4e-34 116.4 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFX99895.1 - 2.1e-30 105.1 0.0 6.7e-30 103.4 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KFX99895.1 - 9.4e-17 61.3 0.0 5.8e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KFX99895.1 - 0.00054 19.5 0.5 0.0022 17.6 0.1 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.23 KFX99895.1 - 0.0014 18.1 2.6 1.9 8.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX99895.1 - 0.0016 19.0 1.2 0.15 12.7 0.3 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX99895.1 - 0.009 16.3 1.9 3.8 7.9 0.6 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX99895.1 - 0.01 15.4 4.7 10 5.8 0.1 4.7 3 2 1 4 4 4 0 TPR repeat Apc3 PF12895.2 KFX99895.1 - 0.017 15.2 0.3 0.71 10.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFX99895.1 - 0.025 14.4 1.9 17 5.4 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.5 KFX99896.1 - 4.2e-15 55.5 6.5 1.4e-13 50.6 4.5 2.0 1 1 0 1 1 1 1 Gon7 family HbrB PF08539.6 KFX99897.1 - 3.7e-50 169.8 0.0 5.6e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 HbrB-like AIP3 PF03915.8 KFX99898.1 - 5.3e-161 536.2 2.0 5.3e-161 536.2 1.4 1.8 2 0 0 2 2 2 1 Actin interacting protein 3 PPI_Ypi1 PF07491.6 KFX99898.1 - 4e-23 80.7 0.6 1.1e-22 79.4 0.4 1.8 1 0 0 1 1 1 1 Protein phosphatase inhibitor Lectin_N PF03954.9 KFX99898.1 - 0.021 14.2 2.7 0.035 13.5 0.1 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FliL PF03748.9 KFX99898.1 - 0.029 14.3 0.4 0.093 12.7 0.3 1.8 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL DUF1664 PF07889.7 KFX99898.1 - 1.3 8.8 4.9 4.6 7.0 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) LsmAD PF06741.8 KFX99900.1 - 6.9e-24 83.7 4.4 6.9e-24 83.7 3.1 2.4 2 0 0 2 2 2 1 LsmAD domain Nipped-B_C PF12830.2 KFX99911.1 - 6.2e-31 107.4 3.1 1.1e-28 100.1 0.1 3.7 4 0 0 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KFX99911.1 - 1.7e-07 31.0 0.4 1.7e-07 31.0 0.3 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 KFX99911.1 - 0.0012 19.1 9.1 0.0046 17.2 0.8 5.2 4 2 3 7 7 7 1 HEAT repeats HEAT PF02985.17 KFX99911.1 - 0.0026 17.7 7.4 28 5.1 0.1 6.7 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.2 KFX99911.1 - 0.0033 17.3 0.9 0.039 13.8 0.1 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KFX99911.1 - 0.33 11.5 5.9 51 4.5 0.1 5.6 6 1 1 7 7 7 0 HEAT-like repeat DNA_pol3_delta PF06144.8 KFX99912.1 - 0.054 13.0 0.2 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SEEEED PF14797.1 KFX99913.1 - 3 7.9 9.5 4.8 7.3 6.6 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Fork_head PF00250.13 KFX99914.1 - 3.3e-34 116.7 0.2 9.3e-34 115.3 0.1 1.7 2 0 0 2 2 2 1 Fork head domain DDE_1 PF03184.14 KFX99915.1 - 3.6e-28 98.1 0.0 8.5e-28 96.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFX99915.1 - 0.021 14.6 0.4 0.36 10.6 0.1 3.1 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 KFX99915.1 - 0.033 13.7 0.2 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Yae1_N PF09811.4 KFX99915.1 - 0.17 11.4 1.4 0.5 9.9 1.0 1.8 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF3295 PF11702.3 KFX99917.1 - 4e-66 224.0 28.3 7.4e-66 223.1 19.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KFX99917.1 - 1.5e-08 34.0 2.1 3.7e-08 32.8 1.4 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SNARE PF05739.14 KFX99918.1 - 6.2e-11 41.8 4.9 6.2e-11 41.8 3.4 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFX99918.1 - 6.9e-07 29.3 2.8 6.9e-07 29.3 2.0 2.4 1 1 0 2 2 2 1 Syntaxin DUF3357 PF11837.3 KFX99918.1 - 0.017 14.9 0.4 0.054 13.3 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF4448 PF14610.1 KFX99918.1 - 0.049 13.1 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Allexi_40kDa PF05549.6 KFX99918.1 - 0.055 12.7 0.1 0.055 12.7 0.1 2.5 1 1 0 2 2 2 0 Allexivirus 40kDa protein MCPsignal PF00015.16 KFX99918.1 - 0.13 11.8 7.8 0.078 12.5 2.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Not3 PF04065.10 KFX99918.1 - 0.3 10.3 6.8 1.1 8.4 4.7 1.8 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Neur_chan_memb PF02932.11 KFX99918.1 - 0.3 10.9 1.9 3.1 7.6 0.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Syntaxin_2 PF14523.1 KFX99918.1 - 4 7.5 9.7 0.38 10.8 2.5 2.3 2 1 1 3 3 3 0 Syntaxin-like protein DUF2203 PF09969.4 KFX99918.1 - 6.1 7.0 7.8 1.5 9.0 1.2 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) F-box-like PF12937.2 KFX99919.1 - 1.6e-07 30.9 0.0 5.7e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX99919.1 - 2e-05 24.0 0.0 7.1e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KFX99919.1 - 6.1 6.5 7.1 53 3.5 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) 5_3_exonuc PF01367.15 KFX99920.1 - 0.55 10.4 2.1 0.43 10.8 0.2 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold APH PF01636.18 KFX99921.1 - 7e-14 52.1 0.2 1e-12 48.3 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX99921.1 - 0.021 14.4 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Methyltransf_23 PF13489.1 KFX99923.1 - 1.7e-15 57.1 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99923.1 - 2.8e-08 33.5 0.0 1.5e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX99923.1 - 1.9e-06 28.4 0.1 2.5e-05 24.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX99923.1 - 3.1e-05 24.3 0.0 0.00012 22.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFX99923.1 - 0.0015 17.9 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KFX99923.1 - 0.0031 17.9 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX99923.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 KFX99923.1 - 0.031 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF1156 PF06634.7 KFX99923.1 - 0.044 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) FtsJ PF01728.14 KFX99923.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFX99923.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFX99923.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KFX99923.1 - 0.12 12.7 0.0 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain SUR7 PF06687.7 KFX99924.1 - 5.4e-11 42.4 17.0 7.1e-11 42.0 11.2 1.6 2 0 0 2 2 2 1 SUR7/PalI family Fig1 PF12351.3 KFX99924.1 - 0.26 11.1 9.1 0.49 10.2 4.8 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 60KD_IMP PF02096.15 KFX99924.1 - 0.51 9.9 4.6 2.3 7.8 3.2 1.8 1 1 0 1 1 1 0 60Kd inner membrane protein Amastin PF07344.6 KFX99924.1 - 0.56 9.8 14.8 0.16 11.5 7.1 2.3 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF2892 PF11127.3 KFX99924.1 - 2.9 7.8 10.0 6.3 6.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF3955 PF13127.1 KFX99924.1 - 5.9 6.5 11.6 0.93 9.0 3.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3955) Chromo PF00385.19 KFX99925.1 - 4.2e-11 42.3 0.2 8.9e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BAH PF01426.13 KFX99928.1 - 1.4e-07 31.2 0.0 3.8e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 BAH domain PHD PF00628.24 KFX99928.1 - 0.0019 17.8 4.1 0.0026 17.3 1.0 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.6 KFX99928.1 - 0.0044 16.9 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 RING-like domain DUF3261 PF11659.3 KFX99928.1 - 0.029 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) DUF4101 PF13355.1 KFX99928.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) Trypsin_2 PF13365.1 KFX99929.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain zf-MIZ PF02891.15 KFX99930.1 - 1e-11 44.1 0.2 2e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.1 KFX99930.1 - 0.0013 18.7 0.1 0.0036 17.3 0.0 1.8 2 0 0 2 2 2 1 PINIT domain zf-Nse PF11789.3 KFX99930.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3295 PF11702.3 KFX99932.1 - 6e-56 190.4 43.1 1.9e-35 122.8 23.0 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KFX99932.1 - 3.9e-05 23.1 2.0 7.9e-05 22.1 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Myb_DNA-binding PF00249.26 KFX99934.1 - 1.8e-11 43.9 4.8 4.4e-09 36.2 0.2 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX99934.1 - 1.1e-07 31.8 1.6 0.00021 21.3 0.1 2.7 1 1 2 3 3 3 2 Myb-like DNA-binding domain DUF1412 PF07203.6 KFX99935.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) OTU PF02338.14 KFX99936.1 - 0.039 14.5 0.0 0.055 14.0 0.0 1.3 1 1 0 1 1 1 0 OTU-like cysteine protease Pertussis_S1 PF02917.9 KFX99936.1 - 0.082 12.4 0.5 0.086 12.3 0.3 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 p450 PF00067.17 KFX99946.1 - 2.8e-12 45.9 0.0 3.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DASH_Hsk3 PF08227.6 KFX99947.1 - 1.7e-21 76.1 0.7 2.2e-21 75.7 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF262 PF03235.9 KFX99949.1 - 1.8e-17 64.1 0.0 8.5e-17 61.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF262 Ipi1_N PF12333.3 KFX99950.1 - 1.8e-23 82.4 0.0 6.2e-23 80.7 0.0 1.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.12 KFX99951.1 - 3.4e-07 29.7 0.0 2.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain BTB PF00651.26 KFX99975.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.1 KFX99976.1 - 0.00037 20.6 3.7 0.0049 17.1 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX99976.1 - 0.00047 20.3 0.4 0.00082 19.5 0.3 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 KFX99976.1 - 0.087 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFX99976.1 - 0.72 10.3 5.5 6.5 7.3 3.8 2.2 1 1 0 1 1 1 0 Zinc finger, C2H2 type GTP_EFTU PF00009.22 KFX99979.1 - 4.1e-58 195.9 0.1 8e-58 194.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KFX99979.1 - 5e-19 68.1 1.7 2e-18 66.2 1.2 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 KFX99979.1 - 3.7e-18 65.5 0.0 1.8e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain DUF3435 PF11917.3 KFX99979.1 - 1.2e-12 47.3 0.0 3.1e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MMR_HSR1 PF01926.18 KFX99979.1 - 2e-05 24.5 0.0 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFX99979.1 - 0.00093 19.6 0.0 0.0025 18.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KFX99979.1 - 0.016 14.8 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF4598 PF15370.1 KFX99980.1 - 2.7e-14 53.3 7.8 2.7e-14 53.3 5.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Treacle PF03546.9 KFX99980.1 - 3.3 6.3 9.9 0.39 9.4 0.6 2.1 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle IF4E PF01652.13 KFX99981.1 - 6e-38 129.9 0.1 7.5e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Las1 PF04031.8 KFX99982.1 - 2e-53 180.1 0.0 3e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Las1-like EF-hand_8 PF13833.1 KFX99982.1 - 0.083 12.5 0.0 25 4.5 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair Alb1 PF09135.6 KFX99983.1 - 6.1e-18 65.4 16.3 9.4e-18 64.8 11.3 1.3 1 0 0 1 1 1 1 Alb1 UCH PF00443.24 KFX99984.1 - 4.1e-42 144.1 0.1 8e-42 143.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX99984.1 - 3.7e-10 39.7 0.0 7.3e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COMPASS-Shg1 PF05205.7 KFX99985.1 - 2e-24 85.8 0.6 4.7e-24 84.7 0.4 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 PRCH PF03967.8 KFX99985.1 - 0.094 12.2 0.2 0.27 10.7 0.1 1.8 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region IF-2B PF01008.12 KFX99987.1 - 3.2e-78 262.5 0.0 4.3e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Lactamase_B PF00753.22 KFX99987.1 - 1.6e-25 89.9 2.4 3.4e-25 88.8 1.7 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX99987.1 - 0.0014 18.1 0.1 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NAD_kinase PF01513.16 KFX99988.1 - 2.8e-66 223.1 0.0 7.8e-66 221.7 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase Cupin_3 PF05899.7 KFX99988.1 - 0.026 13.8 0.0 2.7 7.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF861) PBP PF01161.15 KFX99995.1 - 2.7e-11 43.5 0.0 4.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.17 KFX99996.1 - 1.2e-45 155.2 0.0 1.5e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family RhoGAP PF00620.22 KFX99997.1 - 5.9e-12 45.4 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CBS PF00571.23 KFX99998.1 - 3.3e-29 100.4 10.0 2.2e-13 49.7 0.1 4.3 4 0 0 4 4 4 4 CBS domain Arm PF00514.18 KFX99999.1 - 7.1e-68 222.3 33.6 5.9e-13 48.1 0.1 11.2 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFX99999.1 - 1.7e-22 79.5 15.9 1.2e-06 28.7 0.3 7.5 1 1 7 8 8 8 7 HEAT repeats HEAT PF02985.17 KFX99999.1 - 1.6e-19 68.1 15.8 0.022 14.8 0.1 9.4 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KFX99999.1 - 1.9e-15 56.8 15.5 0.0014 19.0 0.1 8.0 5 3 4 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 KFX99999.1 - 1.2e-12 46.9 9.1 2.8e-08 32.5 0.3 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KFX99999.1 - 1.2e-10 40.9 8.5 0.0067 15.5 0.0 3.6 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 KFX99999.1 - 2.9e-10 39.7 3.2 0.0003 20.0 0.4 3.8 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 KFX99999.1 - 1.5e-09 36.4 0.6 3.2e-09 35.3 0.2 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_PBS PF03130.11 KFX99999.1 - 0.00069 19.8 6.7 2.3 8.9 0.4 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 KFX99999.1 - 0.00072 19.4 3.0 2.9 7.8 0.1 4.5 1 1 5 6 6 6 1 V-ATPase subunit H DUF2454 PF10521.4 KFX99999.1 - 0.0028 16.7 0.1 0.0068 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 KFX99999.1 - 0.021 15.2 0.2 1 9.7 0.1 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KFX99999.1 - 0.024 14.2 0.6 0.47 10.1 0.2 2.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Vpu PF00558.14 KFX99999.1 - 0.051 13.1 2.0 0.078 12.5 0.3 2.1 2 0 0 2 2 2 0 Vpu protein Atx10homo_assoc PF09759.4 KFX99999.1 - 3.7 7.3 6.4 8 6.2 0.0 3.7 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Peptidase_S24 PF00717.18 KFY00001.1 - 3.7e-11 42.5 0.5 6.4e-11 41.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFY00001.1 - 8.3e-05 22.1 0.0 0.0024 17.4 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 DUF4454 PF14628.1 KFY00002.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) KH_1 PF00013.24 KFY00003.1 - 7.1e-41 137.6 16.8 3.7e-15 55.3 0.7 3.7 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KFY00003.1 - 5.4e-29 99.3 20.4 2.4e-10 39.7 0.9 4.4 5 0 0 5 5 5 3 KH domain KH_2 PF07650.12 KFY00003.1 - 1e-12 47.4 4.3 0.0018 17.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFY00003.1 - 2e-08 33.7 5.5 0.1 12.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFY00003.1 - 3.5e-06 26.7 1.1 0.76 9.6 0.0 3.7 3 0 0 3 3 3 3 NusA-like KH domain TIP49 PF06068.8 KFY00004.1 - 2.7e-186 619.0 0.4 3.2e-186 618.8 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KFY00004.1 - 8e-11 42.2 0.3 1.4e-06 28.5 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFY00004.1 - 9.4e-09 34.6 1.7 5.3e-06 25.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFY00004.1 - 2.3e-06 27.7 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KFY00004.1 - 4.1e-05 23.3 0.2 0.03 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFY00004.1 - 4.3e-05 23.6 0.6 0.14 12.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_28 PF13521.1 KFY00004.1 - 8.6e-05 22.5 0.1 0.00019 21.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY00004.1 - 9.4e-05 22.0 0.1 0.00028 20.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KFY00004.1 - 0.00033 20.1 0.0 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFY00004.1 - 0.00059 19.3 0.0 0.82 9.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KFY00004.1 - 0.0014 17.7 0.1 0.0046 16.0 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KFY00004.1 - 0.0035 16.7 0.1 0.0074 15.7 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFY00004.1 - 0.0072 15.5 0.1 0.42 9.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFY00004.1 - 0.0073 16.2 0.0 0.57 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KFY00004.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KFY00004.1 - 0.016 15.4 0.2 0.056 13.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFY00004.1 - 0.023 13.8 0.3 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC MinE PF03776.9 KFY00004.1 - 0.051 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Sigma54_activ_2 PF14532.1 KFY00004.1 - 0.057 13.4 0.0 1 9.4 0.0 2.5 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.1 KFY00004.1 - 0.072 13.9 0.1 0.16 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KFY00004.1 - 0.082 12.1 0.9 0.38 9.9 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein DnaB_C PF03796.10 KFY00004.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HMG_box PF00505.14 KFY00005.1 - 4.9e-21 74.7 1.1 9.4e-21 73.8 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY00005.1 - 1.2e-06 28.7 0.2 2.1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain GAF PF01590.21 KFY00005.1 - 0.015 15.3 1.2 0.03 14.4 0.1 2.0 2 0 0 2 2 2 0 GAF domain Glyco_hydro_63 PF03200.11 KFY00006.1 - 1.1e-08 33.4 4.2 7.4e-07 27.4 0.0 3.4 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase Rep_fac_C PF08542.6 KFY00007.1 - 1.3e-22 79.5 0.1 3.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFY00007.1 - 1.6e-11 44.1 0.0 2.8e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFY00007.1 - 1.5e-06 28.4 0.1 3.3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFY00007.1 - 2.6e-05 24.3 0.5 0.00021 21.4 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY00007.1 - 0.00098 19.1 2.0 0.031 14.2 0.7 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFY00007.1 - 0.0018 18.1 0.1 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KFY00007.1 - 0.0089 16.0 0.2 0.26 11.3 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 KFY00007.1 - 0.011 15.9 0.1 0.02 15.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KFY00007.1 - 0.038 13.6 0.1 0.1 12.2 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2861 PF11060.3 KFY00007.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 KFY00007.1 - 0.043 12.3 0.0 0.15 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.10 KFY00007.1 - 0.057 12.0 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SNF2_N PF00176.18 KFY00007.1 - 0.088 11.5 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_29 PF13555.1 KFY00007.1 - 0.089 12.3 0.0 0.91 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KFY00007.1 - 0.12 11.8 0.1 2.1 7.7 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain Shugoshin_N PF07558.6 KFY00008.1 - 2.8e-14 52.5 3.2 5.6e-14 51.5 2.2 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KFY00008.1 - 1.7e-11 43.3 5.4 1.7e-11 43.3 3.8 3.2 3 0 0 3 3 3 1 Shugoshin C terminus DASH_Dad2 PF08654.5 KFY00009.1 - 2.5e-34 117.3 0.4 3.5e-34 116.8 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 COesterase PF00135.23 KFY00011.1 - 2.6e-94 316.8 0.0 3.3e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY00011.1 - 3.2e-05 23.6 0.1 6.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFY00011.1 - 0.00048 19.4 0.0 0.0021 17.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family BEN PF10523.4 KFY00012.1 - 0.036 14.1 0.2 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 BEN domain Ribosomal_L3 PF00297.17 KFY00013.1 - 1.6e-34 119.5 4.2 1.8e-33 116.0 2.9 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 KFY00014.1 - 3.4e-38 129.7 0.0 4.3e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Phage_GP20 PF06810.6 KFY00017.1 - 2.1e-05 24.0 11.1 2.1e-05 24.0 7.7 10.2 3 2 5 9 9 9 2 Phage minor structural protein GP20 IncA PF04156.9 KFY00017.1 - 5e-05 22.9 134.2 0.0053 16.3 16.5 7.9 3 3 3 8 8 8 5 IncA protein Reo_sigmaC PF04582.7 KFY00017.1 - 5.3e-05 22.5 36.9 0.043 13.0 4.4 6.1 3 2 5 8 8 8 4 Reovirus sigma C capsid protein DUF3584 PF12128.3 KFY00017.1 - 7.7e-05 20.2 41.5 7.7e-05 20.2 28.8 4.5 1 1 2 4 4 4 2 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 KFY00017.1 - 0.00081 19.5 8.8 0.00081 19.5 6.1 7.8 5 3 2 8 8 8 1 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 KFY00017.1 - 0.00095 19.0 149.8 0.009 15.8 12.4 8.6 4 2 3 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 KFY00017.1 - 0.0012 18.9 5.2 0.0012 18.9 3.6 11.1 5 2 6 12 12 11 1 Domain of unknown function (DUF4164) TSC22 PF01166.13 KFY00017.1 - 0.003 17.4 0.2 0.003 17.4 0.2 10.1 7 3 2 10 10 10 2 TSC-22/dip/bun family NPV_P10 PF05531.7 KFY00017.1 - 0.027 14.7 42.4 2.6 8.3 0.6 9.3 5 4 4 9 9 9 0 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.14 KFY00017.1 - 0.33 8.6 149.2 0.014 13.1 38.5 4.8 1 1 4 5 5 5 0 Myosin tail Surfac_D-trimer PF09006.6 KFY00017.1 - 0.41 10.3 5.0 7.6 6.3 0.0 5.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation GAS PF13851.1 KFY00017.1 - 0.52 9.4 122.2 0.11 11.7 13.3 8.4 3 3 3 7 7 7 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 KFY00017.1 - 2 8.2 61.3 0.055 13.2 0.8 8.3 3 2 7 10 10 10 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 KFY00017.1 - 3.5 5.9 92.8 0.74 8.2 23.0 4.9 1 1 3 5 5 5 0 AAA domain DUF2296 PF10058.4 KFY00018.1 - 3e-19 68.4 0.1 5.3e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2721 PF11026.3 KFY00018.1 - 0.25 10.9 1.5 0.5 10.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PAT1 PF09770.4 KFY00018.1 - 6.9 4.7 18.4 10 4.1 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YlaH PF14036.1 KFY00019.1 - 8 6.6 8.8 0.13 12.3 0.5 2.1 3 0 0 3 3 3 0 YlaH-like protein Kelch_1 PF01344.20 KFY00020.1 - 2.8e-39 132.4 8.9 8.6e-09 34.8 0.0 7.4 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 KFY00020.1 - 3.6e-33 112.3 17.5 2.6e-08 33.6 0.1 7.1 2 2 5 7 7 7 6 Kelch motif Kelch_3 PF13415.1 KFY00020.1 - 1.2e-22 79.4 16.6 3e-06 27.2 0.0 6.8 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFY00020.1 - 3.8e-22 77.7 17.1 7.8e-07 28.7 0.0 7.7 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFY00020.1 - 1.3e-16 59.6 4.1 0.001 18.7 0.0 6.3 7 1 0 7 7 7 5 Kelch motif Kelch_5 PF13854.1 KFY00020.1 - 2.3e-16 59.3 8.2 0.0034 17.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif DUF1668 PF07893.8 KFY00020.1 - 8.4e-05 21.8 0.1 0.33 10.0 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1668) SH3_9 PF14604.1 KFY00023.1 - 5.6e-08 32.2 0.0 8.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFY00023.1 - 1.4e-07 30.7 0.0 2.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFY00023.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Syndecan PF01034.15 KFY00023.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.1 KFY00023.1 - 0.22 11.9 1.0 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Carb_kinase PF01256.12 KFY00025.1 - 0.0042 16.4 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase PARP PF00644.15 KFY00026.1 - 6.3e-11 42.0 0.4 3.8e-10 39.5 0.3 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KFY00026.1 - 2.6e-08 33.3 0.0 5.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY00026.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 RWD domain Sds3 PF08598.6 KFY00027.1 - 1e-35 123.1 0.0 1.8e-35 122.3 0.0 1.6 1 1 0 1 1 1 1 Sds3-like Nop PF01798.13 KFY00028.1 - 7.2e-55 184.3 1.6 2.8e-54 182.4 1.1 2.1 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFY00028.1 - 4.8e-24 83.9 0.2 9.1e-24 83.0 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFY00028.1 - 4.4e-21 74.8 2.1 4.4e-21 74.8 1.5 2.9 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF760 PF05542.6 KFY00028.1 - 0.027 14.6 0.1 0.28 11.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF760) vATP-synt_AC39 PF01992.11 KFY00029.1 - 1.3e-116 389.4 0.0 1.4e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 KFY00030.1 - 2.9e-18 65.3 0.3 6.7e-18 64.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 KFY00031.1 - 1e-43 149.0 0.2 5.6e-23 81.2 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 KxDL PF10241.4 KFY00032.1 - 3.8e-23 81.2 1.8 5.1e-23 80.7 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF883 PF05957.8 KFY00032.1 - 0.049 14.0 5.8 0.32 11.4 1.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Peripla_BP_2 PF01497.13 KFY00032.1 - 0.066 12.3 0.1 0.082 12.0 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Lebercilin PF15619.1 KFY00032.1 - 0.15 11.5 6.3 0.22 10.9 4.3 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Mating_C PF12737.2 KFY00032.1 - 3.8 6.2 15.3 1.7 7.4 1.2 2.7 2 1 1 3 3 3 0 C-terminal domain of homeodomain 1 CTP_transf_1 PF01148.15 KFY00033.1 - 2.2e-15 57.0 7.7 2.3e-14 53.6 2.3 2.2 1 1 1 2 2 2 2 Cytidylyltransferase family DEAD PF00270.24 KFY00034.1 - 3.3e-35 121.0 0.0 7.5e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFY00034.1 - 1.7e-18 65.8 0.0 3.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFY00034.1 - 1.1e-17 63.5 0.0 2.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY00034.1 - 0.0033 17.2 0.5 0.026 14.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ubiquitin PF00240.18 KFY00035.1 - 5.1e-05 22.5 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1777 PF08648.7 KFY00035.1 - 0.017 14.8 28.6 0.021 14.5 19.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) YukD PF08817.5 KFY00035.1 - 0.074 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD THRAP3_BCLAF1 PF15440.1 KFY00035.1 - 0.17 10.4 26.2 0.21 10.2 18.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family PseudoU_synth_1 PF01416.15 KFY00036.1 - 2.9e-29 101.5 0.0 5.1e-23 81.5 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 KFY00037.1 - 4.4e-16 58.6 0.0 6.3e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY00037.1 - 1.5e-06 28.6 0.0 2.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein NACHT PF05729.7 KFY00037.1 - 0.0025 17.4 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.16 KFY00037.1 - 0.014 14.5 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family RNA_helicase PF00910.17 KFY00037.1 - 0.022 14.9 0.0 0.047 13.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KFY00037.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 KFY00037.1 - 0.097 11.3 0.0 0.18 10.4 0.0 1.4 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KFY00037.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFY00037.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KFY00037.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_Rpb4 PF03874.11 KFY00038.1 - 1e-18 67.4 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pribosyl_synth PF14572.1 KFY00039.1 - 4.6e-42 143.8 0.9 3e-36 124.8 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFY00039.1 - 3.9e-30 103.9 0.0 1.1e-29 102.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFY00039.1 - 9.7e-11 41.4 0.3 2.4e-10 40.1 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PP2C_2 PF13672.1 KFY00043.1 - 1.3e-10 41.0 0.4 2.1e-10 40.3 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFY00043.1 - 1.5e-09 37.8 0.4 7.6e-09 35.5 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KFY00043.1 - 3.5e-07 29.8 0.1 0.027 13.8 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C DPPIV_N PF00930.16 KFY00044.1 - 2.1e-111 371.9 0.7 2.7e-111 371.5 0.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFY00044.1 - 2.1e-55 187.2 2.5 4e-55 186.3 1.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFY00044.1 - 8.3e-10 38.5 0.2 1.7e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFY00044.1 - 2.1e-07 30.6 1.2 1.3e-05 24.7 0.2 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KFY00044.1 - 9.7e-06 25.6 0.6 0.00018 21.4 0.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFY00044.1 - 0.043 13.0 0.1 0.28 10.4 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 KFY00044.1 - 0.057 11.8 0.0 0.86 8.0 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydro_lipase PF04083.11 KFY00044.1 - 0.084 12.2 1.0 0.36 10.2 0.0 2.6 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.8 KFY00044.1 - 0.093 11.0 0.0 0.55 8.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II TauD PF02668.11 KFY00045.1 - 3.1e-45 154.8 0.0 3.9e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.27 KFY00046.1 - 4.8e-38 127.6 1.6 5.9e-08 32.3 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 KFY00046.1 - 6.4e-30 103.0 17.5 1.1e-29 102.2 12.1 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 KFY00046.1 - 9.8e-05 22.1 0.3 3.8 7.3 0.0 4.6 2 2 4 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 KFY00046.1 - 0.0018 16.6 0.7 0.014 13.7 0.1 2.6 2 1 1 4 4 4 1 Cytochrome D1 heme domain PCI PF01399.22 KFY00047.1 - 7.2e-20 71.2 0.4 2.1e-19 69.8 0.0 2.0 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 KFY00047.1 - 0.0036 16.7 0.2 0.0078 15.6 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.1 KFY00047.1 - 0.0048 16.6 1.0 1 9.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Med2 PF11214.3 KFY00047.1 - 0.02 14.9 0.1 0.11 12.5 0.0 2.2 1 1 0 1 1 1 0 Mediator complex subunit 2 Prefoldin_2 PF01920.15 KFY00047.1 - 0.072 12.8 1.1 0.32 10.7 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit TPR_14 PF13428.1 KFY00047.1 - 1.4 9.7 9.0 31 5.5 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 KFY00053.1 - 1.1e-51 175.5 0.0 1.5e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00053.1 - 2.4e-27 95.6 0.1 7.4e-27 94.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY00053.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.5 KFY00059.1 - 0.51 9.6 2.3 0.86 8.9 1.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2029 PF09594.5 KFY00059.1 - 0.63 9.4 3.7 0.84 9.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) YesK PF14150.1 KFY00059.1 - 0.92 9.6 5.4 0.38 10.8 0.7 2.0 2 0 0 2 2 2 0 YesK-like protein ATG13 PF10033.4 KFY00068.1 - 2.2e-66 223.6 0.0 1.7e-65 220.7 0.0 2.2 3 0 0 3 3 3 1 Autophagy-related protein 13 MFS_1 PF07690.11 KFY00069.1 - 1.7e-27 96.0 29.9 9.2e-26 90.3 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY00069.1 - 0.0047 15.1 1.5 0.0047 15.1 1.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFY00071.1 - 4.9e-38 130.7 32.7 4.9e-38 130.7 22.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY00071.1 - 1.1e-05 24.2 15.3 1.1e-05 24.2 10.6 2.9 2 2 0 2 2 2 1 Sugar (and other) transporter Copper-fist PF00649.13 KFY00072.1 - 1.2e-19 69.1 1.2 1.2e-19 69.1 0.8 3.7 3 2 2 5 5 5 2 Copper fist DNA binding domain Kinetocho_Slk19 PF12709.2 KFY00077.1 - 3.8e-21 74.9 17.5 1.1e-20 73.4 0.9 4.2 4 0 0 4 4 4 2 Central kinetochore-associated HCaRG PF07258.9 KFY00077.1 - 0.013 15.0 0.1 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 HCaRG protein Shugoshin_N PF07558.6 KFY00077.1 - 0.022 14.4 0.0 0.094 12.4 0.0 2.1 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region FlaC_arch PF05377.6 KFY00077.1 - 0.04 13.8 6.3 1.2 9.0 0.1 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Nnf1 PF03980.9 KFY00077.1 - 0.044 13.7 0.3 0.044 13.7 0.2 3.4 4 1 0 4 4 4 0 Nnf1 Tropomyosin PF00261.15 KFY00077.1 - 0.049 12.7 31.6 1.2 8.1 21.0 3.0 2 1 0 2 2 2 0 Tropomyosin bZIP_1 PF00170.16 KFY00077.1 - 0.15 12.0 14.2 0.55 10.2 0.2 4.4 4 1 0 4 4 4 0 bZIP transcription factor IncA PF04156.9 KFY00077.1 - 0.38 10.3 17.6 0.056 13.0 2.2 3.0 2 1 0 2 2 2 0 IncA protein Spc7 PF08317.6 KFY00077.1 - 1.7 7.2 12.5 0.53 8.8 3.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Macoilin PF09726.4 KFY00077.1 - 2.5 6.2 18.2 0.76 7.9 9.7 1.9 1 1 1 2 2 2 0 Transmembrane protein GAS PF13851.1 KFY00077.1 - 3.2 6.8 21.1 1.6 7.8 3.5 3.9 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KFY00077.1 - 3.8 7.3 33.6 2.8 7.8 0.2 4.5 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KFY00077.1 - 7.1 7.0 17.3 18 5.7 0.4 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF972) HALZ PF02183.13 KFY00077.1 - 8.3 6.2 9.1 34 4.2 0.4 4.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Nuf2 PF03800.9 KFY00091.1 - 1.8e-45 154.4 0.6 7e-45 152.6 0.0 2.2 2 0 0 2 2 2 1 Nuf2 family DUF869 PF05911.6 KFY00091.1 - 0.00086 17.6 26.7 0.0011 17.2 18.5 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 KFY00091.1 - 0.0061 15.7 9.3 0.015 14.5 2.0 2.3 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Ndc1_Nup PF09531.5 KFY00091.1 - 0.26 9.6 3.1 0.13 10.7 0.1 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup GAS PF13851.1 KFY00091.1 - 5.8 6.0 40.8 6.5 5.8 10.2 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1515 PF07439.6 KFY00092.1 - 0.22 11.3 2.2 0.53 10.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Thioredoxin PF00085.15 KFY00093.1 - 5e-28 96.8 0.1 6.4e-28 96.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFY00093.1 - 8.3e-08 32.4 0.2 1.5e-06 28.3 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFY00093.1 - 2.2e-05 24.4 0.0 0.00012 22.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KFY00093.1 - 0.0002 20.9 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KFY00093.1 - 0.00068 19.3 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KFY00093.1 - 0.01 15.8 0.2 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 KFY00093.1 - 0.023 14.6 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 KFY00093.1 - 0.027 14.0 0.1 0.077 12.5 0.1 1.7 1 1 1 2 2 2 0 Redoxin Glutaredoxin PF00462.19 KFY00093.1 - 0.047 13.6 0.2 0.42 10.6 0.0 2.1 1 1 1 2 2 2 0 Glutaredoxin Thioredoxin_5 PF13743.1 KFY00093.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Phosducin PF02114.11 KFY00093.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin OTU PF02338.14 KFY00094.1 - 3.6e-14 53.3 0.0 8.3e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 KFY00094.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 KFY00094.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Peptidase_C65 PF10275.4 KFY00094.1 - 0.16 11.3 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain CAF-1_p150 PF11600.3 KFY00094.1 - 9.2 5.5 10.9 7.9 5.7 3.0 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DAO PF01266.19 KFY00095.1 - 9.7e-32 110.2 2.1 2.8e-31 108.7 1.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY00095.1 - 0.0001 22.2 0.1 0.00032 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY00095.1 - 0.0014 17.5 0.0 0.005 15.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KFY00095.1 - 0.0041 16.2 0.1 0.0041 16.2 0.1 2.1 2 1 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 KFY00095.1 - 0.03 14.6 0.1 0.067 13.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY00095.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFY00095.1 - 0.043 12.8 0.1 0.079 11.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KFY00095.1 - 0.067 11.8 0.1 0.43 9.1 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_10 PF13460.1 KFY00096.1 - 3.2e-07 30.5 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY00096.1 - 0.0035 16.8 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY00096.1 - 0.0049 15.8 0.0 0.013 14.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFY00096.1 - 0.013 14.4 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 KFY00098.1 - 5.9e-18 64.6 33.3 9.4e-12 44.3 7.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY00098.1 - 3.9e-11 42.1 12.9 4.9e-10 38.5 2.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFY00098.1 - 0.00064 18.2 12.1 0.0079 14.6 1.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein 2TM PF13239.1 KFY00098.1 - 0.32 11.0 1.9 1.2 9.2 1.3 2.0 1 0 0 1 1 1 0 2TM domain HAD_2 PF13419.1 KFY00099.1 - 9.6e-07 29.1 0.0 1.4e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY00099.1 - 2.1e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFY00099.1 - 0.0018 18.7 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Maf PF02545.9 KFY00099.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Maf-like protein Fructosamin_kin PF03881.9 KFY00100.1 - 8e-34 116.9 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFY00100.1 - 5.7e-08 32.7 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.27 KFY00101.1 - 4e-08 32.8 0.6 0.13 12.1 0.1 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF676 PF05057.9 KFY00101.1 - 1.4e-06 27.7 0.0 3.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.7 KFY00101.1 - 6.5e-06 25.9 0.0 1.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 KFY00101.1 - 1.8e-05 24.4 0.0 4.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFY00101.1 - 0.00029 20.7 0.0 0.00081 19.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KFY00101.1 - 0.001 19.0 0.0 0.0085 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Abhydrolase_5 PF12695.2 KFY00101.1 - 0.0084 15.8 0.0 0.03 14.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family 6PF2K PF01591.13 KFY00101.1 - 0.013 14.6 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Arch_ATPase PF01637.13 KFY00101.1 - 0.027 14.1 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 KFY00101.1 - 0.028 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KFY00101.1 - 0.051 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFY00101.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KFY00101.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KFY00101.1 - 0.12 12.5 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain COPI_assoc PF08507.5 KFY00102.1 - 2.5e-43 147.0 6.3 2.7e-43 146.9 4.4 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KFY00102.1 - 0.074 13.0 3.2 0.1 12.5 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Ycf66_N PF07444.6 KFY00102.1 - 0.17 11.5 2.1 0.34 10.6 1.3 1.7 1 1 0 1 1 1 0 Ycf66 protein N-terminus PGPGW PF09656.5 KFY00102.1 - 0.67 9.2 0.0 0.67 9.2 0.0 2.8 4 0 0 4 4 4 0 Putative transmembrane protein (PGPGW) DUF2583 PF10762.4 KFY00102.1 - 0.96 9.6 3.9 29 4.8 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF3784 PF12650.2 KFY00102.1 - 6.6 6.7 9.8 0.65 9.9 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) GATA PF00320.22 KFY00103.1 - 1.3e-31 107.6 16.8 3.3e-16 58.3 2.6 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFY00103.1 - 3.5e-05 23.0 4.5 0.039 13.2 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KFY00103.1 - 0.00024 20.1 5.8 0.21 10.8 0.2 2.8 2 0 0 2 2 2 2 zinc-ribbon domain ArfGap PF01412.13 KFY00103.1 - 0.0044 16.7 7.9 0.16 11.7 0.1 2.9 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 KFY00103.1 - 0.0047 16.8 2.7 0.99 9.4 0.2 2.6 2 0 0 2 2 2 2 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 KFY00103.1 - 0.0085 15.6 7.4 0.019 14.5 0.2 3.1 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger RRN7 PF11781.3 KFY00103.1 - 0.018 14.5 7.1 0.64 9.5 0.4 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 HypA PF01155.14 KFY00103.1 - 0.021 14.5 1.6 5 6.8 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 KFY00103.1 - 0.034 13.9 5.5 0.16 11.7 0.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 KFY00103.1 - 0.12 12.2 12.1 1.5 8.6 0.1 3.2 2 1 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 KFY00103.1 - 0.22 11.1 5.5 2 8.0 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.7 KFY00103.1 - 0.24 11.1 3.5 8.5 6.2 0.2 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nucleo_P87 PF07267.6 KFY00103.1 - 7.7 5.0 10.8 0.26 9.9 3.4 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Methyltransf_33 PF10017.4 KFY00105.1 - 1.3e-32 112.4 0.0 2.2e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KFY00105.1 - 3.2e-19 69.3 0.5 2.2e-18 66.5 0.4 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KFY00105.1 - 2.9e-07 30.8 0.1 7.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 KFY00105.1 - 0.021 15.1 0.0 0.28 11.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFY00105.1 - 0.096 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PI31_Prot_N PF11566.3 KFY00108.1 - 5.3e-37 126.7 0.0 6.3e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal adh_short PF00106.20 KFY00109.1 - 2.2e-33 115.5 0.0 3.6e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00109.1 - 1.3e-13 51.3 0.1 1.8e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00109.1 - 1.9e-12 47.2 0.0 3.1e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFY00109.1 - 0.0027 17.4 0.1 0.0059 16.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Bacteriocin_IIc PF10439.4 KFY00120.1 - 5.3 7.2 11.5 8.3 6.6 8.0 1.3 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide F-box PF00646.28 KFY00121.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KFY00121.1 - 0.078 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.20 KFY00124.1 - 2.8e-14 52.9 0.4 3.2e-14 52.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00124.1 - 6.4e-09 35.2 0.4 7.5e-09 35.0 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SH2_2 PF14633.1 KFY00125.1 - 7e-85 283.5 0.3 1.8e-84 282.2 0.2 1.8 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KFY00125.1 - 1.3e-36 125.1 6.2 1.3e-36 125.1 4.3 3.4 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 KFY00125.1 - 2.5e-29 101.4 0.0 9.6e-29 99.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.1 KFY00125.1 - 1.4e-27 96.1 0.0 5.5e-27 94.1 0.0 2.1 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KFY00125.1 - 4.2e-22 78.1 20.4 4.2e-22 78.1 14.1 5.7 6 1 0 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KFY00125.1 - 3e-18 65.9 3.4 1.3e-17 63.9 0.6 3.0 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KFY00125.1 - 0.00019 21.1 0.0 0.00058 19.6 0.0 1.9 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 KFY00125.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 S1 RNA binding domain Fungal_trans PF04082.13 KFY00138.1 - 4.7e-28 97.7 0.0 7.4e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00138.1 - 8.6e-11 41.5 11.7 1.5e-10 40.8 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pput2613-deam PF14427.1 KFY00138.1 - 0.1 12.2 0.6 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Pput_2613-like deaminase Chitin_bind_1 PF00187.14 KFY00140.1 - 0.00035 20.4 21.1 0.00035 20.4 14.6 2.2 2 0 0 2 2 2 1 Chitin recognition protein YuzL PF14115.1 KFY00141.1 - 0.014 15.6 1.8 0.024 14.8 1.2 1.4 1 0 0 1 1 1 0 YuzL-like protein DUF912 PF06024.7 KFY00142.1 - 0.041 13.9 0.0 0.096 12.7 0.0 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Plasmodium_Vir PF05795.6 KFY00142.1 - 0.052 12.7 0.8 0.11 11.7 0.5 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein TrbC PF04956.8 KFY00142.1 - 0.062 13.3 0.9 0.12 12.3 0.6 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family CytoC_RC PF02276.13 KFY00158.1 - 0.0051 15.9 0.0 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Photosynthetic reaction centre cytochrome C subunit DUF1765 PF08578.5 KFY00160.1 - 0.00025 21.1 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Kelch_4 PF13418.1 KFY00185.1 - 6.1e-25 86.7 8.7 1.2e-08 34.5 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KFY00185.1 - 3.9e-23 80.9 1.1 4.8e-07 29.6 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KFY00185.1 - 2.8e-20 71.5 2.7 2.4e-05 24.3 0.0 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KFY00185.1 - 4.2e-18 64.6 0.3 7.7e-05 22.1 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 KFY00185.1 - 4.6e-17 61.6 16.1 3.4e-07 30.2 0.0 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KFY00185.1 - 6.8e-15 54.1 2.3 0.0009 18.9 0.0 5.4 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 KFY00185.1 - 4.8e-11 42.6 0.0 9.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Bap31 PF05529.7 KFY00186.1 - 1e-64 217.5 4.9 1.2e-64 217.3 3.4 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Filament PF00038.16 KFY00186.1 - 0.0035 16.8 2.6 0.0054 16.2 1.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.3 KFY00186.1 - 0.011 15.4 5.3 0.014 15.1 3.1 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding She9_MDM33 PF05546.6 KFY00186.1 - 0.012 15.2 0.6 0.022 14.2 0.4 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family Phage_GP20 PF06810.6 KFY00186.1 - 0.016 14.6 5.5 0.028 13.8 3.8 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 KFY00186.1 - 0.017 14.5 4.6 0.024 14.1 0.3 2.7 3 0 0 3 3 3 0 Septum formation initiator Lge1 PF11488.3 KFY00186.1 - 0.041 14.0 0.2 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 KFY00186.1 - 0.059 12.9 0.2 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 KFY00186.1 - 0.31 11.4 1.6 0.46 10.8 0.2 2.0 2 0 0 2 2 2 0 SlyX DUF4446 PF14584.1 KFY00186.1 - 0.59 9.9 3.4 0.88 9.3 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Fungal_trans PF04082.13 KFY00188.1 - 4.7e-27 94.4 0.0 1.2e-26 93.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00188.1 - 1.9e-10 40.4 5.3 3.1e-10 39.7 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2CSK_N PF08521.5 KFY00188.1 - 0.093 12.2 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Two-component sensor kinase N-terminal NOA36 PF06524.7 KFY00189.1 - 0.33 10.1 9.9 0.33 10.1 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 KFY00189.1 - 0.38 9.1 21.7 0.36 9.2 15.1 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 KFY00189.1 - 0.48 10.3 16.9 0.49 10.3 11.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.6 KFY00189.1 - 0.78 9.5 9.9 1.6 8.5 6.9 1.5 1 1 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_Rpc4 PF05132.9 KFY00189.1 - 1.8 8.5 4.6 1.8 8.5 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Trypan_PARP PF05887.6 KFY00189.1 - 2.2 8.1 19.4 2.2 8.0 13.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 KFY00189.1 - 2.4 6.1 14.2 2.5 6.0 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KFY00189.1 - 4.9 6.7 15.7 5.1 6.6 10.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 KFY00189.1 - 5.1 6.4 15.5 5.3 6.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prothymosin PF03247.9 KFY00189.1 - 7 6.8 34.3 12 6.1 23.8 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Radial_spoke PF04712.7 KFY00189.1 - 8 5.0 18.2 7.9 5.1 12.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein PITH PF06201.8 KFY00199.1 - 3.9e-40 137.1 0.0 5.8e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KFY00199.1 - 1.5e-27 95.2 0.1 2.9e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFY00199.1 - 6.5e-09 35.8 0.1 1.6e-06 28.1 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFY00199.1 - 2.5e-06 27.6 0.2 1.1e-05 25.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFY00199.1 - 0.0009 18.8 0.2 0.0024 17.4 0.1 1.8 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KFY00199.1 - 0.0018 17.9 0.1 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 KFY00199.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KFY00199.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 KFY00199.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like TPR_14 PF13428.1 KFY00200.1 - 2.4e-05 24.5 2.4 1.2 10.0 0.1 5.1 5 2 1 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 KFY00200.1 - 3.9e-05 23.5 3.8 0.075 12.7 0.0 2.9 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 KFY00200.1 - 0.00019 22.0 2.1 0.01 16.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00200.1 - 0.014 15.7 0.0 4.2 7.7 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF998 PF06197.8 KFY00201.1 - 0.029 13.7 0.9 0.029 13.7 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF998) UPF0093 PF03653.8 KFY00201.1 - 0.049 13.5 0.2 0.057 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) DUF3756 PF12581.3 KFY00201.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) DUF202 PF02656.10 KFY00201.1 - 0.15 12.3 7.4 0.14 12.3 3.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Zn_clus PF00172.13 KFY00202.1 - 7.4e-08 32.1 6.5 1.1e-07 31.5 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 KFY00202.1 - 0.073 12.6 4.1 0.12 11.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF2763 PF10961.3 KFY00203.1 - 0.2 12.0 4.3 0.086 13.2 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Nsp1_C PF05064.8 KFY00205.1 - 4.1e-38 129.6 0.7 4.1e-38 129.6 0.5 1.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region MscS_porin PF12795.2 KFY00205.1 - 0.0053 16.1 5.1 0.33 10.2 0.1 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 KFY00205.1 - 0.013 13.9 1.2 0.017 13.5 0.8 1.1 1 0 0 1 1 1 0 AAA domain CRIC_ras_sig PF10534.4 KFY00205.1 - 0.018 15.0 0.1 0.073 13.1 0.1 1.9 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras MSP1_C PF07462.6 KFY00205.1 - 0.032 12.6 0.9 0.05 11.9 0.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Tropomyosin_1 PF12718.2 KFY00205.1 - 0.04 13.7 1.9 0.064 13.1 0.6 1.8 1 1 1 2 2 2 0 Tropomyosin like GAS PF13851.1 KFY00205.1 - 0.044 12.9 2.9 1.1 8.3 0.3 2.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 KFY00205.1 - 0.047 13.5 2.7 0.83 9.5 1.4 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Myosin_tail_1 PF01576.14 KFY00205.1 - 0.049 11.3 5.1 0.092 10.4 3.5 1.4 1 1 0 1 1 1 0 Myosin tail APG17 PF04108.7 KFY00205.1 - 0.057 12.2 1.0 1.3 7.6 0.7 2.4 1 1 0 1 1 1 0 Autophagy protein Apg17 Baculo_PEP_C PF04513.7 KFY00205.1 - 0.066 13.0 0.6 0.78 9.5 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KFY00205.1 - 0.072 11.7 4.8 0.56 8.8 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 KFY00205.1 - 0.11 12.2 4.3 5.6 6.7 0.5 3.0 1 1 2 3 3 3 0 Laminin Domain II DUF1664 PF07889.7 KFY00205.1 - 0.12 12.1 1.6 4.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 KFY00205.1 - 0.13 11.7 1.0 0.99 8.9 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator APG6 PF04111.7 KFY00205.1 - 0.24 10.4 6.1 0.12 11.3 2.0 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Muted PF14942.1 KFY00205.1 - 0.24 11.2 2.4 1.7 8.4 0.1 2.5 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein HSBP1 PF06825.7 KFY00205.1 - 0.28 10.7 1.5 0.57 9.7 0.2 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Fib_alpha PF08702.5 KFY00205.1 - 0.32 11.0 1.2 6.6 6.8 0.1 2.6 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family ParB PF08775.5 KFY00205.1 - 0.33 11.2 2.0 0.5 10.6 0.1 2.0 2 1 0 2 2 2 0 ParB family ERM PF00769.14 KFY00205.1 - 2 7.8 6.4 1 8.8 2.3 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 KFY00205.1 - 8.9 6.0 11.4 1.5 8.6 1.6 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein IATP PF04568.7 KFY00206.1 - 1.9e-19 69.5 0.9 2.2e-19 69.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Pam16 PF03656.8 KFY00206.1 - 0.019 14.7 0.2 0.02 14.6 0.1 1.0 1 0 0 1 1 1 0 Pam16 NinG PF05766.7 KFY00206.1 - 0.022 14.4 0.6 0.027 14.1 0.4 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein IncA PF04156.9 KFY00206.1 - 0.039 13.5 0.3 0.039 13.5 0.2 1.1 1 0 0 1 1 1 0 IncA protein RRF PF01765.14 KFY00206.1 - 0.043 13.2 2.9 0.058 12.8 2.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Glutaredoxin2_C PF04399.8 KFY00206.1 - 0.19 11.2 0.8 0.27 10.7 0.5 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain 14-3-3 PF00244.15 KFY00207.1 - 4.2e-117 389.3 7.2 4.9e-117 389.1 5.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 KFY00207.1 - 0.019 14.7 0.3 0.38 10.5 0.0 2.8 1 1 2 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain TPR_19 PF14559.1 KFY00207.1 - 0.32 11.3 3.0 2.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3461 PF11944.3 KFY00207.1 - 3 7.7 7.1 1.7 8.4 0.2 3.0 2 1 1 4 4 4 0 Protein of unknown function (DUF3461) DSPn PF14671.1 KFY00208.1 - 7e-44 149.2 0.0 6e-41 139.7 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFY00208.1 - 5.7e-15 55.0 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFY00208.1 - 2.8e-06 26.8 0.3 5.9e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF3698 PF12479.3 KFY00208.1 - 0.086 12.9 0.1 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Y_phosphatase3 PF13350.1 KFY00208.1 - 0.37 11.0 2.3 0.42 10.8 0.1 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Pcc1 PF09341.5 KFY00209.1 - 1.9e-24 85.4 0.5 2.3e-24 85.2 0.4 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Thioredoxin PF00085.15 KFY00210.1 - 1.9e-62 207.4 8.1 1.4e-30 105.0 0.0 4.1 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 KFY00210.1 - 9.2e-50 169.0 1.9 2e-35 122.2 0.4 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFY00210.1 - 8.4e-11 42.0 3.0 0.00035 20.7 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFY00210.1 - 1.5e-10 41.0 0.1 0.00048 20.1 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KFY00210.1 - 4.3e-10 39.4 0.2 0.0029 17.6 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 KFY00210.1 - 7.9e-09 34.7 1.9 1.7e-08 33.6 0.9 1.7 1 1 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 KFY00210.1 - 1e-06 28.4 1.0 0.0065 16.1 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFY00210.1 - 3.3e-05 23.4 2.7 0.1 12.1 0.0 3.2 3 0 0 3 3 3 2 Redoxin MT0933_antitox PF14013.1 KFY00210.1 - 0.092 12.8 3.4 0.24 11.5 2.3 1.7 1 0 0 1 1 1 0 MT0933-like antitoxin protein Thioredoxin_4 PF13462.1 KFY00210.1 - 0.31 11.0 8.3 1.7 8.6 0.2 4.1 4 0 0 4 4 4 0 Thioredoxin YtxH PF12732.2 KFY00210.1 - 0.96 9.8 9.1 0.33 11.3 2.9 2.8 2 0 0 2 2 2 0 YtxH-like protein DUF883 PF05957.8 KFY00210.1 - 2 8.8 11.5 0.044 14.1 2.9 2.0 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Rad4 PF03835.10 KFY00221.1 - 6.8e-15 54.7 2.2 1.4e-14 53.6 1.5 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KFY00221.1 - 1.8e-12 47.4 3.8 3.7e-12 46.4 2.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Totivirus_coat PF05518.6 KFY00221.1 - 0.25 9.1 1.1 0.38 8.5 0.7 1.2 1 0 0 1 1 1 0 Totivirus coat protein Memo PF01875.12 KFY00222.1 - 1.7e-69 233.7 0.0 2.5e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.27 KFY00222.1 - 1e-11 44.2 7.4 0.36 10.7 0.0 7.7 9 0 0 9 9 9 4 WD domain, G-beta repeat DUF325 PF03804.8 KFY00222.1 - 0.27 10.9 0.8 0.52 10.0 0.1 1.8 2 0 0 2 2 2 0 Viral domain of unknown function C1_4 PF07975.7 KFY00223.1 - 0.018 15.0 5.1 1.3 9.1 1.2 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain FYVE_2 PF02318.11 KFY00223.1 - 0.034 14.0 4.6 0.034 14.0 3.2 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.16 KFY00223.1 - 0.038 13.8 6.1 0.091 12.6 4.3 1.7 1 1 0 1 1 1 0 IBR domain zf-RING_5 PF14634.1 KFY00223.1 - 0.16 11.6 6.6 0.16 11.6 2.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFY00223.1 - 0.49 10.1 8.0 0.17 11.5 2.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C6_DPF PF10170.4 KFY00223.1 - 1.9 8.6 7.8 0.28 11.2 2.4 1.8 2 0 0 2 2 2 0 Cysteine-rich domain zf-B_box PF00643.19 KFY00223.1 - 2.2 8.2 12.7 0.35 10.7 2.2 2.6 2 0 0 2 2 2 0 B-box zinc finger Siva PF05458.7 KFY00223.1 - 5.7 6.4 9.7 2.8 7.4 3.7 2.3 3 0 0 3 3 3 0 Cd27 binding protein (Siva) SNARE PF05739.14 KFY00224.1 - 4.4e-11 42.2 5.4 4.4e-11 42.2 3.8 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFY00224.1 - 4.3e-09 36.4 2.1 4.3e-09 36.4 1.4 2.4 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.4 KFY00224.1 - 1.3e-06 28.0 8.8 1.9e-06 27.5 6.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Vac_Fusion PF02346.11 KFY00224.1 - 0.00092 18.5 1.3 0.04 13.3 0.0 2.8 3 0 0 3 3 3 1 Chordopoxvirus fusion protein Rifin_STEVOR PF02009.11 KFY00224.1 - 0.0019 17.8 4.3 0.0019 17.8 3.0 2.1 1 1 1 2 2 2 1 Rifin/stevor family ODV-E18 PF10717.4 KFY00224.1 - 0.0024 17.2 0.2 0.0024 17.2 0.1 1.8 2 0 0 2 2 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF1510 PF07423.6 KFY00224.1 - 0.017 14.4 1.2 0.017 14.4 0.8 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1510) SecG PF03840.9 KFY00224.1 - 0.021 14.5 0.2 0.054 13.2 0.2 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit T2SF PF00482.18 KFY00224.1 - 0.058 13.3 3.5 0.27 11.1 1.6 2.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F L6_membrane PF05805.7 KFY00224.1 - 0.077 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 L6 membrane protein MCPsignal PF00015.16 KFY00224.1 - 0.11 12.0 13.0 0.086 12.3 5.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HHH_2 PF12826.2 KFY00224.1 - 0.11 12.3 0.4 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3753 PF12575.3 KFY00224.1 - 0.14 11.9 3.0 0.33 10.7 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Chordopox_A13L PF05961.6 KFY00224.1 - 0.16 11.9 2.0 0.46 10.4 1.4 1.7 1 0 0 1 1 1 0 Chordopoxvirus A13L protein P12 PF12669.2 KFY00224.1 - 0.2 11.8 1.0 0.37 11.0 0.7 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family FUSC PF04632.7 KFY00224.1 - 0.25 9.7 5.5 0.51 8.7 3.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family PBP1_TM PF14812.1 KFY00224.1 - 0.49 10.7 0.0 0.49 10.7 0.0 2.5 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MitMem_reg PF13012.1 KFY00224.1 - 0.5 10.4 7.7 0.16 12.0 1.4 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Spectrin PF00435.16 KFY00224.1 - 0.5 10.6 11.4 1.4 9.2 0.3 3.2 2 1 1 3 3 3 0 Spectrin repeat Syntaxin_2 PF14523.1 KFY00224.1 - 0.74 9.8 12.7 0.1 12.6 1.6 3.0 1 1 2 3 3 3 0 Syntaxin-like protein DUF2116 PF09889.4 KFY00224.1 - 0.87 9.4 3.1 3.2 7.6 2.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Allexi_40kDa PF05549.6 KFY00224.1 - 1.3 8.3 8.9 0.18 11.0 0.3 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF4094 PF13334.1 KFY00224.1 - 1.8 8.9 10.2 0.16 12.3 1.1 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) Homeobox PF00046.24 KFY00225.1 - 7.8e-06 25.4 0.6 1.4e-05 24.5 0.4 1.5 1 0 0 1 1 1 1 Homeobox domain Phosducin PF02114.11 KFY00226.1 - 3.9e-13 48.7 0.0 4.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Phosducin NUFIP1 PF10453.4 KFY00226.1 - 0.018 14.5 1.0 0.03 13.8 0.7 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Exo_endo_phos PF03372.18 KFY00227.1 - 1.8e-08 34.6 0.0 2.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PTPLA PF04387.9 KFY00229.1 - 1.8e-51 173.8 10.0 3.1e-51 173.0 7.0 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Pardaxin PF07425.6 KFY00229.1 - 0.13 11.7 1.3 0.55 9.6 0.0 2.5 3 0 0 3 3 3 0 Pardaxin Adaptin_binding PF10199.4 KFY00230.1 - 1.3e-12 48.2 3.1 7.6e-07 29.4 0.1 2.8 3 0 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 DUF2120 PF09893.4 KFY00230.1 - 0.059 13.3 0.7 0.14 12.1 0.5 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) FAD_binding_7 PF03441.9 KFY00231.1 - 3.4e-92 308.5 0.8 4.9e-92 308.0 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFY00231.1 - 1.9e-40 138.2 0.0 3.1e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Peptidase_S8 PF00082.17 KFY00242.1 - 5.7e-48 163.4 14.5 8.1e-48 162.9 10.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFY00242.1 - 1.6e-10 41.4 0.1 2.9e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 adh_short PF00106.20 KFY00243.1 - 1.5e-19 70.5 0.0 4e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFY00243.1 - 3.7e-06 27.0 0.1 6.9e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFY00243.1 - 0.0038 16.9 0.1 0.01 15.5 0.1 1.8 1 1 0 1 1 1 1 KR domain 4HBT PF03061.17 KFY00243.1 - 0.025 14.7 0.2 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily NAD_binding_2 PF03446.10 KFY00243.1 - 0.025 14.4 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HHH_5 PF14520.1 KFY00243.1 - 0.092 12.9 0.2 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Imm_superinfect PF14373.1 KFY00270.1 - 0.0098 15.5 1.1 0.033 13.8 0.8 1.9 2 0 0 2 2 2 1 Superinfection immunity protein TMF_DNA_bd PF12329.3 KFY00270.1 - 0.0098 15.6 0.2 0.018 14.8 0.2 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding adh_short PF00106.20 KFY00270.1 - 0.01 15.7 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Acetyltransf_8 PF13523.1 KFY00271.1 - 2.3e-45 154.1 0.1 3.8e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFY00271.1 - 8.6e-05 22.7 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3279 PF11682.3 KFY00271.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) NAD_binding_10 PF13460.1 KFY00273.1 - 8.2e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFY00273.1 - 5.9e-05 21.9 0.0 8.2e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KFY00273.1 - 0.00039 20.3 0.0 0.00088 19.1 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KFY00273.1 - 0.0023 18.2 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KFY00273.1 - 0.0044 16.4 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 KFY00273.1 - 0.023 15.2 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 KFY00273.1 - 0.035 13.0 0.0 0.12 11.2 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein PsbX PF06596.6 KFY00278.1 - 0.052 13.2 1.0 0.13 11.9 0.7 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF4191 PF13829.1 KFY00278.1 - 0.27 10.3 1.0 0.29 10.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1049 PF06305.6 KFY00278.1 - 0.31 10.5 4.2 0.5 9.8 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Ctr PF04145.10 KFY00280.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family MFS_1 PF07690.11 KFY00283.1 - 5.3e-34 117.4 26.6 5.3e-34 117.4 18.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA_25 PF13481.1 KFY00283.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1049 PF06305.6 KFY00283.1 - 2.1 7.8 5.8 18 4.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Glyco_hydro_88 PF07470.8 KFY00284.1 - 9.5e-87 291.1 2.6 1.1e-86 290.9 1.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFY00284.1 - 0.059 11.6 0.3 0.25 9.5 0.2 1.8 1 1 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 KFY00284.1 - 0.48 9.7 7.7 0.41 9.9 0.6 2.5 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 CBM-like PF14683.1 KFY00285.1 - 2.8e-41 140.9 0.0 4.8e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFY00285.1 - 1.7e-23 82.5 0.5 6.8e-23 80.6 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KFY00285.1 - 3e-08 33.6 0.1 2.6e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KFY00285.1 - 0.066 13.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) CBM-like PF14683.1 KFY00286.1 - 2.6e-13 49.9 0.1 4.6e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFY00286.1 - 4.1e-10 39.6 0.3 1.4e-09 37.9 0.2 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II UCH_1 PF13423.1 KFY00291.1 - 1.7e-25 90.0 0.4 2.7e-25 89.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GTP_EFTU PF00009.22 KFY00292.1 - 9e-44 149.1 0.0 2e-43 148.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFY00292.1 - 1.3e-20 73.4 0.1 4.2e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFY00292.1 - 2.4e-05 24.3 0.4 5.9e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFY00292.1 - 3e-05 23.9 0.0 7.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFY00292.1 - 0.01 14.5 2.5 0.022 13.4 1.7 1.5 1 1 0 1 1 1 0 G-protein alpha subunit Ran-binding PF05508.6 KFY00293.1 - 1.8e-103 345.6 0.0 2.3e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein TRAUB PF08164.7 KFY00294.1 - 1.5e-30 105.1 0.3 1.1e-29 102.3 0.0 2.6 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KFY00294.1 - 9.6e-26 90.4 6.8 9.6e-26 90.4 4.7 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor ParA PF10609.4 KFY00295.1 - 5.7e-34 115.8 0.2 1.3e-33 114.7 0.1 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFY00295.1 - 1.6e-14 53.7 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFY00295.1 - 1.2e-08 35.0 0.1 9.7e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KFY00295.1 - 2.4e-05 23.5 0.0 3.5e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KFY00295.1 - 0.00058 19.0 0.8 0.013 14.5 0.3 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KFY00295.1 - 0.0026 17.2 0.1 0.0074 15.7 0.1 1.9 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KFY00295.1 - 0.017 14.3 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KFY00295.1 - 0.017 14.7 0.1 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFY00295.1 - 0.13 12.0 1.0 7.5 6.3 0.0 2.9 4 0 0 4 4 4 0 Part of AAA domain PH_10 PF15411.1 KFY00310.1 - 1.6e-23 83.0 0.0 2e-22 79.5 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 KFY00310.1 - 9.4e-08 31.7 5.9 1.7e-07 30.9 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFY00310.1 - 0.00022 20.7 2.1 0.0004 19.9 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 KFY00310.1 - 0.00033 20.8 0.0 0.00076 19.6 0.0 1.6 1 0 0 1 1 1 1 PH domain zf-RING_5 PF14634.1 KFY00310.1 - 0.00041 20.0 5.4 0.00071 19.2 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFY00310.1 - 0.00084 19.3 4.8 0.0015 18.4 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFY00310.1 - 0.00084 19.3 1.5 0.0017 18.4 1.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFY00310.1 - 0.012 15.2 4.6 0.023 14.3 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KFY00310.1 - 0.22 11.5 4.8 0.44 10.5 3.3 1.5 1 0 0 1 1 1 0 RING-like domain O-FucT PF10250.4 KFY00316.1 - 0.0015 17.6 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ATP-synt_C PF00137.16 KFY00334.1 - 6.4e-17 61.2 17.3 6.4e-17 61.2 12.0 1.8 2 0 0 2 2 2 1 ATP synthase subunit C DUF3353 PF11833.3 KFY00334.1 - 0.27 10.6 4.9 4 6.8 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Gly-zipper_OmpA PF13436.1 KFY00334.1 - 2 8.0 7.0 3 7.5 4.9 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Fungal_trans PF04082.13 KFY00335.1 - 1.2e-13 50.6 5.2 1.7e-13 50.0 3.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KFY00336.1 - 1.2e-83 281.2 24.1 1.4e-83 281.0 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00336.1 - 3.2e-17 62.2 56.8 3.2e-16 58.9 21.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY00336.1 - 0.0001 20.8 4.4 0.0001 20.8 3.0 3.8 2 2 2 4 4 4 2 MFS/sugar transport protein Alpha-amylase PF00128.19 KFY00337.1 - 4.6e-98 328.4 0.0 8.4e-98 327.6 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KFY00337.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_hydro_49 PF03718.8 KFY00338.1 - 1.9e-194 646.9 14.7 2.4e-194 646.6 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 Glyco_hydro_28 PF00295.12 KFY00338.1 - 0.0022 17.0 0.0 0.0046 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_35 PF01301.14 KFY00339.1 - 1.1e-75 254.8 2.0 2.4e-75 253.8 1.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KFY00339.1 - 1.3e-61 207.1 0.0 2.1e-61 206.4 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KFY00339.1 - 1.7e-47 160.2 9.1 2.4e-25 88.9 2.1 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KFY00339.1 - 1.4e-23 82.0 0.1 3e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 FAM183 PF14886.1 KFY00339.1 - 0.091 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 FAM183A and FAM183B related Glyco_hydro_31 PF01055.21 KFY00340.1 - 4.4e-170 566.2 0.2 5.4e-170 565.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFY00340.1 - 1.6e-11 43.9 1.6 3e-10 39.7 0.5 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like CUE PF02845.11 KFY00351.1 - 2.3e-11 42.9 0.0 4.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 KFY00351.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF3697 PF12478.3 KFY00351.1 - 0.0021 17.6 0.1 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 UBA_4 PF14555.1 KFY00351.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Ras PF00071.17 KFY00362.1 - 1.6e-54 183.6 0.0 1.9e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY00362.1 - 2.1e-15 57.2 0.0 2.9e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY00362.1 - 3.8e-09 36.0 0.0 7.5e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFY00362.1 - 3.2e-06 26.4 0.0 3.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFY00362.1 - 0.0031 16.2 0.0 0.0047 15.6 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.5 KFY00362.1 - 0.0096 15.1 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFY00362.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFY00362.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 KFY00362.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain CWC25 PF12542.3 KFY00363.1 - 4.3e-26 91.1 2.3 4.3e-26 91.1 1.6 3.5 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KFY00363.1 - 1.6e-11 43.9 13.4 1.6e-11 43.9 9.3 3.9 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2937 PF11157.3 KFY00363.1 - 0.58 9.4 4.5 1.1 8.6 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PCI PF01399.22 KFY00364.1 - 6.5e-19 68.1 0.1 6.5e-19 68.1 0.1 2.5 3 1 0 3 3 2 1 PCI domain PCI_Csn8 PF10075.4 KFY00364.1 - 1.8e-06 27.7 0.2 4.9e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KFY00364.1 - 0.00013 21.4 0.6 0.16 11.8 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFY00364.1 - 0.00049 19.9 0.0 0.39 10.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFY00364.1 - 0.006 16.4 1.9 0.83 9.6 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFY00364.1 - 0.0064 16.3 2.6 0.061 13.2 0.1 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.13 KFY00364.1 - 0.014 15.2 0.7 0.065 13.1 0.3 2.3 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 KFY00364.1 - 0.019 14.5 1.8 0.091 12.4 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFY00364.1 - 0.032 13.8 0.4 0.28 10.8 0.0 2.7 3 0 0 3 3 3 0 TPR repeat AAA_10 PF12846.2 KFY00364.1 - 0.042 13.2 1.1 0.52 9.6 0.1 2.3 2 1 0 2 2 2 0 AAA-like domain TPR_8 PF13181.1 KFY00364.1 - 0.088 12.6 0.1 0.088 12.6 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFY00364.1 - 0.15 12.6 0.8 2.5 8.7 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.1 KFY00366.1 - 4.1e-08 33.6 0.0 7.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFY00366.1 - 4.9e-07 29.2 0.0 9.4e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ISK_Channel PF02060.10 KFY00367.1 - 0.005 16.4 0.0 47 3.5 0.0 4.5 5 0 0 5 5 5 2 Slow voltage-gated potassium channel Ank_2 PF12796.2 KFY00368.1 - 1.2e-85 281.9 0.0 1.1e-18 67.3 0.0 7.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFY00368.1 - 1.2e-81 264.6 10.6 1.1e-06 28.1 0.1 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_3 PF13606.1 KFY00368.1 - 2.8e-57 184.9 0.4 5e-05 23.1 0.0 14.0 14 0 0 14 14 13 11 Ankyrin repeat Ank_4 PF13637.1 KFY00368.1 - 6e-57 189.0 0.1 1.3e-08 35.1 0.0 9.8 4 4 6 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY00368.1 - 5.7e-49 163.0 10.7 5.2e-06 26.5 0.0 12.9 2 2 12 14 14 14 13 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 KFY00368.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFY00368.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFY00368.1 - 0.0022 17.6 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFY00368.1 - 0.0052 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFY00368.1 - 0.0058 16.2 0.0 0.24 10.9 0.0 3.0 3 0 0 3 3 3 1 Serine hydrolase DUF2305 PF10230.4 KFY00368.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) FHA PF00498.21 KFY00369.1 - 9e-17 60.9 0.1 3.2e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 FHA domain TUDOR PF00567.19 KFY00369.1 - 0.16 11.7 0.2 5 6.9 0.0 2.8 3 0 0 3 3 3 0 Tudor domain DUF607 PF04678.8 KFY00369.1 - 7 6.5 6.9 4.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF607 EMP24_GP25L PF01105.19 KFY00369.1 - 7.3 6.2 7.6 2 8.0 0.2 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SIR2 PF02146.12 KFY00370.1 - 8.3e-56 188.5 0.0 1.2e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Complex1_LYR PF05347.10 KFY00374.1 - 2.5e-08 33.5 0.0 3.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFY00374.1 - 4.5e-08 33.1 0.0 6.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like UQ_con PF00179.21 KFY00375.1 - 1.5e-18 66.5 0.0 1.7e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY00375.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 KFY00376.1 - 3.8e-39 133.7 3.8 4.3e-39 133.6 0.2 3.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFY00376.1 - 0.0002 20.8 0.1 0.0074 15.7 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Band_7 PF01145.20 KFY00377.1 - 9.4e-32 110.3 0.4 9.4e-32 110.3 0.3 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFY00377.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family zf-U1 PF06220.7 KFY00378.1 - 0.00026 20.4 0.5 0.00052 19.5 0.3 1.5 1 0 0 1 1 1 1 U1 zinc finger MARVEL PF01284.18 KFY00379.1 - 1.3e-07 31.5 15.7 1.2e-05 25.1 10.9 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF4234 PF14018.1 KFY00379.1 - 0.0089 15.7 0.6 0.0089 15.7 0.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4234) VIT1 PF01988.14 KFY00379.1 - 0.018 14.5 0.9 0.018 14.5 0.6 1.4 1 1 1 2 2 2 0 VIT family CorA PF01544.13 KFY00379.1 - 0.11 11.4 0.8 0.18 10.8 0.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 KFY00379.1 - 0.27 9.7 4.4 0.25 9.8 2.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 KFY00379.1 - 0.84 9.0 5.8 1.8 7.9 3.8 1.7 1 1 0 1 1 1 0 Fatty acid desaturase O-antigen_lig PF13425.1 KFY00379.1 - 1.5 8.8 8.7 0.52 10.2 2.7 2.4 1 1 2 3 3 3 0 O-antigen ligase like membrane protein DUF3816 PF12822.2 KFY00379.1 - 5.7 6.7 11.4 8.3 6.2 7.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Amidoligase_2 PF12224.3 KFY00380.1 - 1.3e-29 103.5 0.0 2e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Gtr1_RagA PF04670.7 KFY00380.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1126 PF06565.7 KFY00382.1 - 0.13 11.7 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF1126) Spo7 PF03907.8 KFY00382.1 - 1.4 8.4 4.8 13 5.2 0.1 2.6 3 0 0 3 3 3 0 Spo7-like protein DUF3328 PF11807.3 KFY00383.1 - 7e-34 117.4 0.4 8.9e-34 117.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Gly_transf_sug PF04488.10 KFY00391.1 - 3.8e-12 46.4 0.1 7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GN3L_Grn1 PF08701.6 KFY00392.1 - 1.7e-23 82.3 12.7 1.7e-23 82.3 8.8 1.7 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KFY00392.1 - 2.7e-05 24.1 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFY00392.1 - 0.00018 21.3 2.9 0.00034 20.4 2.0 1.6 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 KFY00392.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KFY00392.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Retinal PF15449.1 KFY00392.1 - 3.2 5.2 8.4 4.2 4.9 5.8 1.1 1 0 0 1 1 1 0 Retinal protein APG6 PF04111.7 KFY00392.1 - 4.4 6.2 6.9 7.9 5.4 4.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 HAD_2 PF13419.1 KFY00393.1 - 1.7e-15 57.6 0.0 2.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY00393.1 - 6.3e-11 41.8 0.1 1.2e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFY00393.1 - 8.8e-09 36.0 0.0 4.4e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY00393.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 KFY00393.1 - 0.25 10.8 1.8 0.58 9.7 0.6 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase adh_short PF00106.20 KFY00394.1 - 1e-17 64.5 1.3 1.4e-17 64.1 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00394.1 - 7e-13 48.9 0.3 8.7e-13 48.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00394.1 - 9.5e-08 31.9 0.3 1.2e-07 31.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY00394.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pec_lyase_C PF00544.14 KFY00395.1 - 9.8e-07 28.4 0.7 6.4e-05 22.5 0.2 2.1 1 1 1 2 2 2 2 Pectate lyase Aldedh PF00171.17 KFY00396.1 - 5.2e-107 358.0 0.1 6.1e-107 357.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeobox PF00046.24 KFY00397.1 - 2.3e-13 49.5 1.4 4.9e-13 48.4 0.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFY00397.1 - 0.034 13.8 0.1 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain SUR7 PF06687.7 KFY00401.1 - 1.4e-17 64.0 9.0 8.2e-17 61.4 4.4 2.0 1 1 1 2 2 2 2 SUR7/PalI family Claudin_2 PF13903.1 KFY00401.1 - 7.9e-05 22.4 4.3 7.9e-05 22.4 3.0 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.9 KFY00401.1 - 0.00072 19.3 0.5 0.00072 19.3 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF805) DUF161 PF02588.10 KFY00401.1 - 0.027 14.7 2.0 0.091 13.0 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 RCR PF12273.3 KFY00401.1 - 0.04 14.4 0.1 0.04 14.4 0.1 2.3 4 0 0 4 4 3 0 Chitin synthesis regulation, resistance to Congo red COX2_TM PF02790.10 KFY00401.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2663 PF10864.3 KFY00401.1 - 0.34 11.1 0.1 0.34 11.1 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) 7tm_1 PF00001.16 KFY00401.1 - 0.51 9.4 4.2 0.087 11.9 0.1 1.7 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) EI24 PF07264.6 KFY00401.1 - 1.8 7.9 10.2 0.28 10.5 3.5 1.9 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Phage_holin_4 PF05105.7 KFY00401.1 - 2.1 8.0 7.9 0.69 9.5 1.6 2.2 2 0 0 2 2 2 0 Holin family DctM PF06808.7 KFY00401.1 - 3.1 6.2 11.2 0.37 9.3 1.6 2.0 2 0 0 2 2 2 0 DctM-like transporters FtsX PF02687.16 KFY00401.1 - 3.2 7.5 11.4 0.19 11.4 2.3 2.2 2 0 0 2 2 2 0 FtsX-like permease family MRAP PF15183.1 KFY00401.1 - 5.3 6.7 8.6 0.62 9.6 0.1 2.8 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family SIT PF15330.1 KFY00401.1 - 5.7 7.1 0.0 5.7 7.1 0.0 2.8 4 0 0 4 4 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1282 PF06930.7 KFY00401.1 - 9.9 5.7 9.1 0.35 10.4 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) TPR_10 PF13374.1 KFY00402.1 - 3.5e-102 331.8 12.9 7.7e-09 35.1 0.0 11.3 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.1 KFY00402.1 - 2e-89 293.5 29.3 2.8e-15 56.0 0.2 9.7 2 1 9 11 11 11 10 Tetratricopeptide repeat TPR_4 PF07721.9 KFY00402.1 - 1.5e-17 62.1 0.0 3.1 8.5 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFY00402.1 - 4.5e-16 58.2 6.0 0.001 18.6 0.0 7.0 3 2 6 9 9 9 7 TPR repeat TPR_17 PF13431.1 KFY00402.1 - 8e-14 50.6 4.0 0.26 11.5 0.0 10.9 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFY00402.1 - 8.7e-14 51.7 0.0 0.086 13.5 0.0 7.7 2 1 8 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFY00402.1 - 1.4e-13 49.8 2.0 3.9 7.2 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY00402.1 - 6e-13 47.6 1.1 1.9 8.5 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00402.1 - 1.1e-08 35.2 5.5 0.00035 20.8 0.0 5.6 3 3 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY00402.1 - 8.3e-06 25.2 12.2 1.3 8.9 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat Herpes_UL33 PF03581.8 KFY00402.1 - 7.5e-05 22.5 4.8 7.6 6.5 0.0 6.3 4 1 2 6 6 6 0 Herpesvirus UL33-like protein TPR_8 PF13181.1 KFY00402.1 - 0.00096 18.7 9.1 45 4.1 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF956 PF06115.6 KFY00402.1 - 0.0059 16.1 0.0 47 3.6 0.0 4.3 4 2 1 5 5 4 0 Domain of unknown function (DUF956) Enolase_C PF00113.17 KFY00402.1 - 0.0085 15.0 1.7 16 4.3 0.0 4.8 2 1 4 6 6 6 0 Enolase, C-terminal TIM barrel domain Terminase_2 PF03592.11 KFY00402.1 - 0.035 14.3 12.0 2.9 8.1 0.1 5.3 4 1 0 4 4 4 0 Terminase small subunit DUF2526 PF10735.4 KFY00402.1 - 0.061 13.3 15.7 2.4 8.1 0.1 6.6 4 3 4 8 8 7 0 Protein of unknown function (DUF2526) MGDG_synth PF06925.6 KFY00402.1 - 0.077 12.8 0.1 4.5 7.1 0.0 2.9 1 1 1 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase TPR_20 PF14561.1 KFY00402.1 - 0.22 11.6 12.0 8.2 6.6 0.0 5.9 2 2 6 8 8 8 0 Tetratricopeptide repeat L27 PF02828.11 KFY00402.1 - 1.3 8.7 16.5 70 3.2 0.0 7.0 8 0 0 8 8 8 0 L27 domain TPR_14 PF13428.1 KFY00402.1 - 1.9 9.3 12.3 1.1e+02 3.8 0.0 7.4 7 2 3 10 10 9 0 Tetratricopeptide repeat F-box-like PF12937.2 KFY00403.1 - 0.00039 20.0 1.9 0.0031 17.2 0.0 3.2 4 0 0 4 4 4 1 F-box-like F-box PF00646.28 KFY00403.1 - 0.026 14.1 0.1 6.1 6.6 0.0 2.8 2 0 0 2 2 2 0 F-box domain DUF2089 PF09862.4 KFY00403.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) zf-CCCH PF00642.19 KFY00423.1 - 8.4e-21 73.1 25.6 1.4e-07 30.9 0.3 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UPF0254 PF06787.6 KFY00425.1 - 0.11 11.9 0.7 0.15 11.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Gly-zipper_OmpA PF13436.1 KFY00425.1 - 0.54 9.9 3.2 0.71 9.5 2.2 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Sporozoite_P67 PF05642.6 KFY00425.1 - 6.1 4.5 8.1 6.4 4.5 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YbjQ_1 PF01906.12 KFY00427.1 - 4.1e-32 110.7 0.4 4.8e-32 110.5 0.3 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Mt_ATP-synt_B PF05405.9 KFY00428.1 - 7e-50 168.6 4.9 8.7e-50 168.3 3.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) tRNA_anti-codon PF01336.20 KFY00428.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_trans PF02486.14 KFY00428.1 - 0.098 12.1 1.1 0.17 11.3 0.8 1.4 1 1 0 1 1 1 0 Replication initiation factor CBF PF03914.12 KFY00429.1 - 3e-46 156.8 0.8 9.2e-46 155.2 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family Cytadhesin_P30 PF07271.6 KFY00436.1 - 2.2 7.4 11.8 3.7 6.7 2.5 2.3 2 0 0 2 2 2 0 Cytadhesin P30/P32 RNase_T PF00929.19 KFY00437.1 - 1.8e-25 90.1 0.0 3.2e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease FRG2 PF15315.1 KFY00437.1 - 1.6 8.6 7.0 4 7.3 4.9 1.6 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Yippee-Mis18 PF03226.9 KFY00438.1 - 3e-05 23.9 0.3 6.7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Syntaxin PF00804.20 KFY00438.1 - 0.99 9.5 6.0 37 4.5 0.3 3.6 2 1 1 3 3 3 0 Syntaxin Ofd1_CTDD PF10637.4 KFY00440.1 - 4.3e-43 147.3 0.0 4.2e-38 131.0 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KFY00440.1 - 1.7e-14 54.1 0.0 3.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GFA PF04828.9 KFY00441.1 - 2.7e-12 46.4 9.4 7.4e-08 32.2 0.2 3.1 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KFY00441.1 - 0.00041 19.8 2.9 0.19 11.2 0.1 2.8 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.8 KFY00441.1 - 0.0051 16.2 7.4 1 8.9 0.1 3.6 3 0 0 3 3 3 2 CSL zinc finger zf-ribbon_3 PF13248.1 KFY00441.1 - 0.022 13.9 5.8 0.69 9.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KFY00441.1 - 0.23 11.1 0.1 0.23 11.1 0.1 4.0 4 0 0 4 4 4 0 Nudix N-terminal DZR PF12773.2 KFY00441.1 - 0.75 9.6 8.9 0.97 9.3 0.0 3.2 4 0 0 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFY00441.1 - 2.6 7.6 9.0 2.3 7.8 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Cytochrome_C554 PF13435.1 KFY00441.1 - 7.2 6.6 8.2 0.85 9.6 1.5 2.1 2 0 0 2 2 2 0 Cytochrome c554 and c-prime Pkinase PF00069.20 KFY00444.1 - 6.9e-64 215.4 0.0 9.7e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00444.1 - 1.9e-29 102.5 0.0 3.5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFY00444.1 - 1.8e-10 40.7 0.1 3.3e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 KFY00444.1 - 0.0035 16.4 0.0 0.0095 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFY00444.1 - 0.0094 14.9 0.0 0.023 13.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like p450 PF00067.17 KFY00445.1 - 8.6e-50 169.5 0.0 1.4e-49 168.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Diphthamide_syn PF01866.12 KFY00445.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein ResB PF05140.9 KFY00445.1 - 0.12 10.9 1.7 0.17 10.3 1.1 1.1 1 0 0 1 1 1 0 ResB-like family Patatin PF01734.17 KFY00449.1 - 1.6e-20 73.9 0.1 6.1e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase DUF4047 PF13256.1 KFY00449.1 - 0.022 14.7 1.4 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) CENP-F_leu_zip PF10473.4 KFY00449.1 - 0.15 11.9 4.4 0.36 10.6 3.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_2 PF13923.1 KFY00449.1 - 1.6 8.8 7.0 5.6 7.0 4.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 KFY00450.1 - 0.1 12.1 1.8 0.2 11.2 1.1 1.6 1 1 1 2 2 2 0 IncA protein K-box PF01486.12 KFY00450.1 - 0.14 11.9 2.1 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 K-box region TACC PF05010.9 KFY00450.1 - 0.23 11.2 4.4 0.43 10.2 3.1 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF1041 PF06292.12 KFY00450.1 - 0.89 9.7 5.3 0.81 9.8 1.4 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) Toxin_39 PF15500.1 KFY00451.1 - 0.056 13.5 0.1 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Putative RNase-like toxin Skp1 PF01466.14 KFY00452.1 - 1.8e-06 27.8 0.0 6.9e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFY00452.1 - 3.9e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ank_2 PF12796.2 KFY00453.1 - 2.5e-13 50.1 0.0 4.3e-10 39.7 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY00453.1 - 4.8e-11 41.8 0.1 0.0028 17.3 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFY00453.1 - 8e-07 29.4 0.0 0.027 14.9 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY00453.1 - 8e-06 25.6 0.0 0.047 13.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 KFY00453.1 - 3.9e-05 23.7 0.0 0.17 12.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) TPR_11 PF13414.1 KFY00454.1 - 1.1e-08 34.5 8.6 2e-08 33.7 3.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFY00454.1 - 3.4e-08 32.7 3.7 0.03 13.9 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY00454.1 - 4.5e-06 26.1 8.5 0.22 11.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFY00454.1 - 7.8e-05 23.2 8.0 0.0034 17.9 2.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFY00454.1 - 0.0056 16.3 1.3 4.1 7.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat CZB PF13682.1 KFY00454.1 - 0.078 13.1 0.2 4.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Chemoreceptor zinc-binding domain TPR_14 PF13428.1 KFY00454.1 - 0.81 10.4 5.0 13 6.7 0.8 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat MatE PF01554.13 KFY00456.1 - 1.3e-06 28.0 1.2 1.6e-06 27.8 0.8 1.0 1 0 0 1 1 1 1 MatE SIR2 PF02146.12 KFY00457.1 - 4.6e-23 81.8 0.0 1.4e-22 80.3 0.0 1.8 1 1 0 1 1 1 1 Sir2 family SET PF00856.23 KFY00457.1 - 2.6e-08 34.3 0.0 1.3e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 SET domain DUF2296 PF10058.4 KFY00457.1 - 0.047 13.4 0.4 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) F-box PF00646.28 KFY00458.1 - 0.0036 16.9 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 F-box domain Orn_Arg_deC_N PF02784.11 KFY00459.1 - 1.4e-61 207.8 0.0 1.8e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFY00459.1 - 9.6e-15 54.3 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cu_amine_oxid PF01179.15 KFY00460.1 - 3.7e-166 552.9 0.0 4.7e-166 552.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFY00460.1 - 7.7e-20 70.8 0.0 1.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFY00460.1 - 2.1e-14 53.3 0.0 4.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain BCA_ABC_TP_C PF12399.3 KFY00460.1 - 0.067 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter DUF2450 PF10475.4 KFY00466.1 - 1.1e-05 24.4 2.3 2.1e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KFY00466.1 - 0.037 13.6 1.2 0.26 10.9 0.2 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain MCM PF00493.18 KFY00467.1 - 8.5e-144 478.3 0.2 1.1e-143 477.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFY00467.1 - 1.2e-20 74.1 0.1 3.7e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFY00467.1 - 9.6e-08 31.4 0.1 5.8e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFY00467.1 - 9.2e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFY00467.1 - 0.00056 19.5 0.1 0.0021 17.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFY00467.1 - 0.0035 16.8 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 KFY00467.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KFY00467.1 - 0.046 14.1 0.3 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1048 PF06304.6 KFY00468.1 - 0.042 14.1 0.0 0.048 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) MafB19-deam PF14437.1 KFY00468.1 - 0.047 13.3 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase MFS_1 PF07690.11 KFY00474.1 - 3e-13 49.2 21.2 4.3e-13 48.7 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.14 KFY00475.1 - 1.6e-45 154.5 0.0 3.2e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TauD PF02668.11 KFY00475.1 - 6.5e-44 150.5 0.1 9.6e-44 149.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mo-co_dimer PF03404.11 KFY00475.1 - 1.7e-23 82.7 4.4 5.5e-23 81.0 3.0 1.9 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 KFY00475.1 - 0.16 11.9 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 SLBB domain WD40 PF00400.27 KFY00476.1 - 2.9e-41 137.8 20.0 7.4e-09 35.1 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 KFY00476.1 - 1.4e-10 40.7 0.0 2.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KFY00476.1 - 8.9e-07 27.4 0.5 0.018 13.1 0.0 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 KFY00476.1 - 3.9e-05 23.1 0.0 8.6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain DASH_Dam1 PF08653.5 KFY00476.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF605 PF04652.11 KFY00477.1 - 1.3 8.3 12.5 1.5 8.1 8.7 1.1 1 0 0 1 1 1 0 Vta1 like GPI-anchored PF10342.4 KFY00489.1 - 2.5e-07 31.0 0.0 3.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Antimicrobial10 PF08105.6 KFY00489.1 - 0.3 10.7 2.4 0.48 10.0 1.6 1.7 1 1 0 1 1 1 0 Metchnikowin family adh_short PF00106.20 KFY00495.1 - 1.3e-17 64.2 0.6 1.3e-17 64.2 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFY00495.1 - 4.8e-11 42.6 0.1 8.2e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 KFY00496.1 - 1.7e-12 47.0 0.0 3.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY00496.1 - 6.9e-08 32.2 0.2 2.1e-07 30.6 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFY00496.1 - 0.051 14.4 0.0 0.099 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HhH-GPD PF00730.20 KFY00497.1 - 1.4e-15 57.4 0.0 2.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2668 PF10873.3 KFY00497.1 - 0.52 10.4 3.0 7 6.7 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) TFIIF_alpha PF05793.7 KFY00497.1 - 5 5.3 6.5 7.2 4.8 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Anp1 PF03452.9 KFY00498.1 - 3.2e-103 344.5 0.0 3.9e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 Cu-oxidase_2 PF07731.9 KFY00499.1 - 0.051 13.0 0.1 0.15 11.5 0.1 1.8 2 0 0 2 2 2 0 Multicopper oxidase MFS_1 PF07690.11 KFY00500.1 - 2.2e-31 108.8 67.3 7.1e-29 100.6 37.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY00500.1 - 1.9e-12 46.5 10.7 1.9e-12 46.5 7.4 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter Oxidored_FMN PF00724.15 KFY00502.1 - 1.1e-82 277.7 0.0 1.4e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans_2 PF11951.3 KFY00503.1 - 0.00029 19.5 0.3 0.00095 17.8 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TMEM107 PF14995.1 KFY00503.1 - 0.72 9.9 4.5 3.6 7.7 0.7 2.2 2 0 0 2 2 2 0 Transmembrane protein MFS_1 PF07690.11 KFY00504.1 - 1.6e-14 53.4 22.1 2e-14 53.0 15.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY00506.1 - 0.0041 15.7 0.9 0.0043 15.6 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_3 PF07859.8 KFY00509.1 - 1.8e-21 76.7 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFY00509.1 - 6e-09 36.1 0.4 2.4e-08 34.1 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY00509.1 - 0.0079 15.9 0.0 0.0088 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 KFY00509.1 - 0.032 12.9 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF3336 PF11815.3 KFY00511.1 - 9.9e-39 132.1 0.3 2e-38 131.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFY00511.1 - 3.2e-26 92.5 0.0 1.3e-25 90.5 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase adh_short PF00106.20 KFY00534.1 - 3.2e-30 105.2 2.2 4.8e-30 104.6 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00534.1 - 4.3e-30 105.2 0.5 5.7e-30 104.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00534.1 - 9.3e-14 51.4 0.3 1.5e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY00534.1 - 8.1e-06 25.4 0.4 1.7e-05 24.3 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 KFY00534.1 - 0.00077 19.1 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 PA domain DFP PF04127.10 KFY00534.1 - 0.0098 15.5 0.8 0.067 12.7 0.4 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein HEM4 PF02602.10 KFY00534.1 - 0.015 14.5 0.2 0.25 10.5 0.0 2.5 1 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Polysacc_synt_2 PF02719.10 KFY00534.1 - 0.065 12.1 0.1 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lipase_GDSL_2 PF13472.1 KFY00538.1 - 2.6e-26 92.8 0.0 3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KFY00538.1 - 2.9e-07 30.3 0.0 1.2e-05 25.1 0.0 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY00538.1 - 0.00066 19.5 0.0 0.0027 17.5 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase 2-Hacid_dh_C PF02826.14 KFY00539.1 - 4.2e-36 123.7 0.0 1.4e-23 82.9 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFY00539.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KFY00539.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KFY00539.1 - 0.083 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 KFY00539.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ERG4_ERG24 PF01222.12 KFY00542.1 - 6.5e-146 486.2 20.3 8.3e-146 485.8 14.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Glyco_hydro_1 PF00232.13 KFY00543.1 - 5e-78 262.3 0.9 3.5e-76 256.2 0.6 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans_2 PF11951.3 KFY00543.1 - 1.1e-34 119.6 0.2 3.6e-34 118.0 0.2 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00543.1 - 4.1e-09 36.1 5.1 4.1e-09 36.1 3.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 KFY00544.1 - 1e-46 159.5 0.0 1.5e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFY00544.1 - 0.14 11.4 0.0 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Nitrate_red_del PF02613.10 KFY00544.1 - 0.15 11.8 0.1 3.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Nitrate reductase delta subunit GMC_oxred_N PF00732.14 KFY00545.1 - 6.1e-63 212.7 0.0 7.9e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY00545.1 - 2.6e-34 118.6 0.0 4.3e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFY00545.1 - 9.6e-06 24.6 1.3 0.019 13.8 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KFY00545.1 - 5.2e-05 22.4 0.3 0.023 13.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 KFY00545.1 - 0.0021 18.0 0.6 0.0062 16.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY00545.1 - 0.0023 16.8 2.0 0.079 11.8 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY00545.1 - 0.0029 16.5 0.5 0.0058 15.5 0.3 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFY00545.1 - 0.1 12.4 0.3 0.29 10.9 0.1 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF202 PF02656.10 KFY00546.1 - 0.53 10.5 5.7 4.2 7.6 4.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4231 PF14015.1 KFY00546.1 - 6.2 6.8 5.7 10 6.1 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MIF PF01187.13 KFY00547.1 - 0.00029 20.8 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Atg14 PF10186.4 KFY00547.1 - 0.15 10.9 3.2 0.23 10.3 2.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4110 PF13422.1 KFY00547.1 - 0.19 11.6 5.5 0.16 11.8 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF3211 PF11485.3 KFY00547.1 - 1.6 8.7 5.8 0.41 10.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3211) ELO PF01151.13 KFY00548.1 - 1.3e-80 270.3 9.0 1.5e-80 270.0 6.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_39 PF01229.12 KFY00548.1 - 0.059 11.7 0.0 0.095 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Gtr1_RagA PF04670.7 KFY00552.1 - 3.9e-69 232.3 0.1 4.6e-69 232.1 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFY00552.1 - 0.00045 20.7 0.0 0.00075 19.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY00552.1 - 0.0016 17.7 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFY00552.1 - 0.072 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.18 KFY00553.1 - 2.2e-75 253.0 2.4 3.2e-75 252.5 1.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFY00553.1 - 1.3e-41 140.8 0.4 1.3e-41 140.8 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFY00553.1 - 3.6e-06 26.6 1.3 1e-05 25.1 0.9 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFY00553.1 - 0.014 15.0 1.6 0.23 11.1 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L50 PF10501.4 KFY00554.1 - 2e-21 76.0 0.1 3.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S PetM PF08041.6 KFY00555.1 - 0.2 11.1 0.8 0.4 10.2 0.6 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 DAHP_synth_1 PF00793.15 KFY00556.1 - 8.4e-93 309.9 0.1 1.8e-92 308.8 0.1 1.5 1 1 0 1 1 1 1 DAHP synthetase I family PBP-Tp47_a PF14889.1 KFY00556.1 - 0.074 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a SelR PF01641.13 KFY00558.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 SelR domain Pex14_N PF04695.8 KFY00558.1 - 3.1 7.8 6.2 2 8.4 3.0 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 KFY00559.1 - 4.3e-62 209.6 0.0 6.7e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00559.1 - 6.8e-28 97.4 0.0 9.8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY00559.1 - 0.00014 20.9 0.0 0.00029 19.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3621 PF12285.3 KFY00559.1 - 0.094 12.8 0.3 0.094 12.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) APH PF01636.18 KFY00559.1 - 0.21 11.2 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family eIF3_subunit PF08597.5 KFY00559.1 - 2.2 7.7 15.9 3.4 7.1 11.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3987 PF13148.1 KFY00559.1 - 7.7 4.9 15.1 11 4.4 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rtf2 PF04641.7 KFY00559.1 - 8.9 5.4 10.8 16 4.6 7.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Methyltransf_28 PF02636.12 KFY00560.1 - 1.3e-80 270.4 0.0 1.8e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase EHN PF06441.7 KFY00561.1 - 6.2e-37 125.9 1.8 2.1e-36 124.2 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFY00561.1 - 1.5e-13 51.1 0.5 3.2e-13 50.0 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY00561.1 - 5.2e-10 39.2 0.0 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold RRM_1 PF00076.17 KFY00562.1 - 0.00042 19.8 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY00562.1 - 0.00087 19.2 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2457 PF10446.4 KFY00563.1 - 0.99 8.0 10.0 1.9 7.1 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MoaC PF01967.16 KFY00564.1 - 3.8e-50 169.0 0.3 6.5e-50 168.3 0.2 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KFY00564.1 - 2.9e-34 117.4 0.0 6.5e-34 116.3 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KFY00564.1 - 5.2e-21 75.5 0.0 1.1e-20 74.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KFY00564.1 - 0.00098 19.2 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KFY00564.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain IKI3 PF04762.7 KFY00565.1 - 6.9e-07 27.5 0.0 3.8e-06 25.0 0.0 1.8 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.6 KFY00565.1 - 0.00087 19.0 0.2 5.8 6.5 0.0 4.0 4 1 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KFY00565.1 - 0.0024 17.7 10.2 3.7 7.5 0.3 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.7 KFY00565.1 - 0.17 11.5 2.0 0.52 10.0 0.0 2.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat EBP PF05241.7 KFY00566.1 - 1.2e-65 220.2 8.5 1.4e-65 219.9 5.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein TRIC PF05197.8 KFY00566.1 - 0.097 12.0 4.4 0.81 9.0 0.7 2.3 2 0 0 2 2 2 0 TRIC channel Bac_surface_Ag PF01103.18 KFY00567.1 - 6.4e-43 147.4 1.0 8.2e-43 147.0 0.7 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 KFY00568.1 - 9.3e-26 89.9 0.2 1.3e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY00568.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 RWD domain zf-C2H2_4 PF13894.1 KFY00570.1 - 1.2e-07 31.5 12.9 0.083 13.2 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFY00570.1 - 0.0022 18.2 2.3 1.2 9.5 0.3 3.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-TRAF PF02176.13 KFY00570.1 - 0.016 15.6 0.6 0.068 13.5 0.4 2.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2 PF00096.21 KFY00570.1 - 0.018 15.3 20.9 0.2 12.0 0.6 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type NmrA PF05368.8 KFY00571.1 - 4e-30 104.7 0.0 8.6e-30 103.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY00571.1 - 1.6e-05 24.9 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KFY00571.1 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 KFY00571.1 - 0.15 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 KFY00572.1 - 9.9e-19 67.6 0.0 1.8e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00572.1 - 3.2e-07 30.9 0.0 3.7e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY00572.1 - 3.5e-07 29.9 0.0 3.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY00572.1 - 0.00035 20.9 0.0 0.0013 19.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY00572.1 - 0.00036 20.9 0.0 0.00079 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY00572.1 - 0.0015 18.8 0.0 0.0037 17.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFY00572.1 - 0.01 14.8 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KFY00572.1 - 0.014 15.3 0.0 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFY00572.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KFY00572.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain HET PF06985.6 KFY00573.1 - 2.9e-34 118.1 0.1 1.2e-33 116.2 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 KFY00573.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Phg_2220_C PF09524.5 KFY00573.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) ketoacyl-synt PF00109.21 KFY00590.1 - 1.2e-82 277.2 0.5 3.8e-82 275.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFY00590.1 - 3.4e-38 130.1 0.1 1.2e-37 128.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KFY00590.1 - 1.4e-35 123.1 2.4 2.2e-35 122.5 1.7 1.3 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 KFY00590.1 - 3.9e-05 22.7 0.1 7.7e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PolyG_pol PF01518.11 KFY00590.1 - 0.27 9.6 0.0 0.42 9.0 0.0 1.2 1 0 0 1 1 1 0 Sigma NS protein DEAD PF00270.24 KFY00592.1 - 3.8e-45 153.4 0.0 7.4e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFY00592.1 - 6.6e-27 92.8 0.1 1.5e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFY00592.1 - 1.6e-21 75.9 0.0 4.9e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFY00592.1 - 0.054 12.2 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DEAD PF00270.24 KFY00593.1 - 1.1e-45 155.2 0.0 2e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 KFY00593.1 - 2.9e-24 84.6 3.7 7.9e-24 83.2 2.6 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 KFY00593.1 - 6.8e-21 73.9 0.0 7.6e-20 70.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain FAD_binding_4 PF01565.18 KFY00595.1 - 3.4e-16 58.9 0.9 6.4e-16 58.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY00595.1 - 7.5e-08 32.1 0.0 2.9e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like DUF3429 PF11911.3 KFY00641.1 - 3.4e-39 134.0 7.0 4.5e-39 133.6 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1510 PF07423.6 KFY00641.1 - 0.00041 19.7 3.1 0.00073 18.9 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2413 PF10310.4 KFY00659.1 - 1.2e-112 376.9 0.0 1.5e-112 376.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KFY00659.1 - 0.0076 16.2 0.2 0.032 14.2 0.1 2.0 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain Pkinase PF00069.20 KFY00660.1 - 2.7e-69 233.2 0.0 4.1e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00660.1 - 1.9e-31 109.0 0.0 5.1e-30 104.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY00660.1 - 0.0033 16.4 0.8 1.2 8.0 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KFY00660.1 - 0.0048 16.6 0.0 0.11 12.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KFY00660.1 - 0.037 13.3 0.2 0.084 12.2 0.1 1.6 1 1 0 1 1 1 0 RIO1 family Fungal_trans PF04082.13 KFY00661.1 - 0.0074 15.1 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFY00662.1 - 1.2e-19 70.2 24.1 4.3e-13 48.7 0.5 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily SYF2 PF08231.7 KFY00663.1 - 1.8e-52 177.4 13.5 1.8e-52 177.4 9.4 2.1 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 KFY00663.1 - 0.01 15.8 1.0 0.01 15.8 0.7 3.0 2 1 1 3 3 3 1 ARD/ARD' family NAD_binding_10 PF13460.1 KFY00664.1 - 1.9e-13 50.8 0.0 3e-12 46.9 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY00664.1 - 1e-07 31.6 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFY00664.1 - 7.7e-05 21.5 0.0 0.00015 20.5 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFY00664.1 - 0.0025 16.8 0.0 0.083 11.8 0.0 2.5 3 1 0 3 3 3 1 Male sterility protein adh_short PF00106.20 KFY00664.1 - 0.0046 16.8 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KFY00664.1 - 0.072 11.9 0.0 0.71 8.6 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain YEATS PF03366.11 KFY00665.1 - 6.3e-30 102.7 0.1 1.1e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 YEATS family DUF4407 PF14362.1 KFY00666.1 - 8.9 5.1 14.6 7.6 5.3 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DEAD PF00270.24 KFY00667.1 - 5.1e-34 117.1 0.0 8e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY00667.1 - 4.2e-18 64.9 0.0 1.5e-16 59.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY00667.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 KFY00668.1 - 1.2e-28 99.5 0.0 1.8e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY00668.1 - 8.5e-27 93.4 0.0 1.4e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY00668.1 - 5.5e-22 78.2 0.0 9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY00668.1 - 1.9e-18 66.7 0.0 3.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY00668.1 - 3.7e-18 65.4 0.0 7.8e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFY00668.1 - 3.8e-15 56.4 0.1 9.5e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY00668.1 - 5.3e-15 55.6 0.0 9.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY00668.1 - 6.1e-09 35.9 0.4 1.4e-08 34.7 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFY00668.1 - 1.2e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KFY00668.1 - 3.7e-08 32.9 0.0 5.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFY00668.1 - 8.4e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KFY00668.1 - 0.00029 20.0 0.0 0.00041 19.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFY00668.1 - 0.0003 19.9 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 KFY00668.1 - 0.00031 19.2 0.0 0.00039 18.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 KFY00668.1 - 0.0031 16.2 0.0 0.0044 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KFY00668.1 - 0.0059 15.7 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KFY00668.1 - 0.0084 16.1 0.2 0.016 15.2 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase DREV PF05219.7 KFY00668.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.6 KFY00668.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) FmrO PF07091.6 KFY00668.1 - 0.018 14.0 0.1 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 KFY00668.1 - 0.045 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KFY00668.1 - 0.053 12.6 0.2 0.074 12.2 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 KFY00668.1 - 0.06 12.3 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GCD14 PF08704.5 KFY00668.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit p450 PF00067.17 KFY00669.1 - 3.4e-58 197.3 0.0 4.1e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3851 PF12962.2 KFY00669.1 - 0.042 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) CBFD_NFYB_HMF PF00808.18 KFY00670.1 - 4.1e-13 49.1 1.4 6.8e-13 48.4 1.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFY00670.1 - 3.1e-07 30.4 0.7 6e-07 29.4 0.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.8 KFY00670.1 - 1.9 8.3 16.5 3.1 7.5 11.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cir_N PF10197.4 KFY00671.1 - 0.34 10.9 2.3 0.74 9.8 1.6 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF892 PF05974.7 KFY00672.1 - 0.00028 20.7 0.5 0.00028 20.7 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF892) DUF948 PF06103.6 KFY00672.1 - 0.0045 16.8 1.5 0.49 10.2 0.1 2.8 3 0 0 3 3 2 1 Bacterial protein of unknown function (DUF948) HALZ PF02183.13 KFY00672.1 - 0.0046 16.6 0.4 0.012 15.2 0.3 1.8 1 0 0 1 1 1 1 Homeobox associated leucine zipper WXG100 PF06013.7 KFY00672.1 - 0.012 15.6 0.4 1.6 8.7 0.0 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG PilJ PF13675.1 KFY00672.1 - 0.013 15.8 1.2 3.6 7.9 0.1 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MscS_porin PF12795.2 KFY00672.1 - 0.026 13.8 2.8 1.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain THOC7 PF05615.8 KFY00672.1 - 0.032 14.5 7.0 0.45 10.7 1.4 2.6 2 1 0 2 2 2 0 Tho complex subunit 7 LXG PF04740.7 KFY00672.1 - 0.033 13.9 3.3 0.091 12.5 0.2 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF148 PF02520.12 KFY00672.1 - 0.047 13.4 4.7 0.28 10.9 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF2433 PF10360.4 KFY00672.1 - 0.15 12.4 0.8 7.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2433) BCDHK_Adom3 PF10436.4 KFY00672.1 - 0.15 11.5 1.0 0.42 10.1 0.1 2.1 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Syntaxin-6_N PF09177.6 KFY00672.1 - 0.21 12.0 4.4 8.9 6.7 0.1 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal UPF0449 PF15136.1 KFY00672.1 - 0.29 11.3 6.8 6.3 7.0 1.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 APG6 PF04111.7 KFY00672.1 - 0.34 9.8 12.2 0.067 12.2 5.6 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1319 PF07028.6 KFY00672.1 - 0.35 11.0 4.4 4.7 7.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Fib_alpha PF08702.5 KFY00672.1 - 0.42 10.7 3.2 14 5.7 0.1 2.7 3 0 0 3 3 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.19 KFY00672.1 - 0.44 10.2 6.2 0.064 12.9 0.3 2.2 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc24 PF08286.6 KFY00672.1 - 0.47 10.1 6.6 1.8 8.3 0.1 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Orthopox_A5L PF06193.6 KFY00672.1 - 0.51 10.2 3.5 9.2 6.1 0.3 2.3 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Viral_P18 PF04521.8 KFY00672.1 - 0.51 9.7 4.4 3.1 7.2 0.2 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Hemerythrin PF01814.18 KFY00672.1 - 0.54 10.4 9.6 7 6.8 3.4 2.9 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Prefoldin PF02996.12 KFY00672.1 - 0.73 9.4 10.7 0.78 9.4 0.6 3.2 3 1 1 4 4 3 0 Prefoldin subunit bZIP_1 PF00170.16 KFY00672.1 - 0.89 9.5 11.0 2.5 8.1 1.3 2.8 2 1 0 2 2 2 0 bZIP transcription factor Kinetocho_Slk19 PF12709.2 KFY00672.1 - 0.93 9.6 8.5 5.2 7.2 0.5 2.9 2 1 0 2 2 2 0 Central kinetochore-associated AATF-Che1 PF13339.1 KFY00672.1 - 1.4 9.1 6.8 12 6.0 0.2 3.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Bacillus_HBL PF05791.6 KFY00672.1 - 2.1 7.6 5.1 7.6 5.8 0.2 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ApoC-I PF04691.7 KFY00672.1 - 2.3 7.9 7.2 5.7 6.7 1.5 3.2 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) IncA PF04156.9 KFY00672.1 - 4 6.9 18.0 5.5 6.5 6.7 2.7 1 1 1 2 2 2 0 IncA protein DUF972 PF06156.8 KFY00672.1 - 4.7 7.6 8.7 7.2 7.0 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-K PF11802.3 KFY00672.1 - 4.9 6.3 10.2 10 5.2 2.3 2.4 1 1 1 2 2 2 0 Centromere-associated protein K SPX PF03105.14 KFY00672.1 - 5.7 6.6 6.3 11 5.6 4.4 1.7 1 1 0 1 1 1 0 SPX domain Prefoldin_2 PF01920.15 KFY00672.1 - 6.2 6.6 15.2 2.1 8.1 0.8 2.9 2 1 0 2 2 2 0 Prefoldin subunit GrpE PF01025.14 KFY00672.1 - 6.4 6.2 16.7 22 4.5 2.0 4.1 2 1 1 3 3 3 0 GrpE V_ATPase_I PF01496.14 KFY00672.1 - 6.5 4.4 10.9 23 2.6 7.6 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 KFY00672.1 - 7.8 6.3 8.1 18 5.1 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CTP_synth_N PF06418.9 KFY00673.1 - 5.9e-120 399.5 0.3 8.1e-120 399.0 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFY00673.1 - 3e-54 183.3 0.0 5.5e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFY00673.1 - 3.9e-08 33.0 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KFY00673.1 - 0.0052 16.1 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Lyase_1 PF00206.15 KFY00674.1 - 2e-20 73.1 0.1 3.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KFY00674.1 - 2.1e-11 43.6 0.0 7.7e-11 41.8 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF3328 PF11807.3 KFY00675.1 - 9e-32 110.5 0.6 1.2e-31 110.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TauD PF02668.11 KFY00691.1 - 1.3e-07 31.5 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_17 PF13207.1 KFY00692.1 - 0.00018 22.2 0.1 0.00038 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFY00692.1 - 0.00034 20.4 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFY00692.1 - 0.00037 19.6 0.0 0.00089 18.3 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KFY00692.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFY00692.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFY00692.1 - 0.046 13.4 0.0 0.2 11.4 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KFY00692.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KFY00692.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 KFY00692.1 - 0.23 10.6 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Aminotran_1_2 PF00155.16 KFY00693.1 - 1.5e-12 47.1 0.0 1.6e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RE_NgoFVII PF09565.5 KFY00693.1 - 0.05 12.5 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Hexapep PF00132.19 KFY00696.1 - 1e-13 50.0 6.7 1.2e-09 37.1 1.6 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFY00696.1 - 5.5e-13 48.2 8.3 1.1e-10 40.8 1.1 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KFY00696.1 - 2.2e-12 46.7 0.0 3.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Ycf1 PF05758.7 KFY00709.1 - 0.076 10.7 5.9 0.079 10.6 4.1 1.0 1 0 0 1 1 1 0 Ycf1 Rubella_E2 PF05749.6 KFY00709.1 - 0.11 11.7 0.2 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 NCKAP5 PF15246.1 KFY00709.1 - 0.2 10.9 16.1 0.29 10.4 11.1 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Spore_coat_CotO PF14153.1 KFY00709.1 - 0.37 10.2 10.8 0.45 9.9 7.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Auts2 PF15336.1 KFY00709.1 - 0.38 10.7 7.7 0.87 9.5 5.3 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein CAF-1_p150 PF11600.3 KFY00709.1 - 0.51 9.6 27.3 0.74 9.1 18.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HlyD_2 PF12700.2 KFY00709.1 - 0.67 9.0 5.5 0.72 8.9 3.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Bud13 PF09736.4 KFY00709.1 - 1.3 9.2 13.8 1.8 8.8 9.6 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Asp-B-Hydro_N PF05279.6 KFY00709.1 - 2.2 8.0 14.1 2.9 7.6 9.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.6 KFY00709.1 - 5.1 5.2 22.1 6.4 4.9 15.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2146 PF10220.4 KFY00709.1 - 5.3 4.8 9.9 6.5 4.5 6.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF1510 PF07423.6 KFY00709.1 - 6.5 6.0 14.9 9.5 5.5 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 KFY00709.1 - 9 3.8 7.1 9.9 3.6 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tyrosinase PF00264.15 KFY00717.1 - 7.8e-52 176.6 0.1 1.1e-51 176.1 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Phage_tail_T PF06223.7 KFY00717.1 - 0.15 12.5 0.2 0.93 9.9 0.0 2.3 3 0 0 3 3 3 0 Minor tail protein T XFP_N PF09364.5 KFY00718.1 - 5.2e-178 591.3 0.0 6.9e-178 590.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KFY00718.1 - 1.6e-87 292.2 0.0 2.3e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KFY00718.1 - 5.3e-80 267.1 0.0 1.1e-79 266.1 0.0 1.6 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase E1_dh PF00676.15 KFY00718.1 - 0.15 10.7 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Dehydrogenase E1 component Fructosamin_kin PF03881.9 KFY00719.1 - 2.9e-30 105.2 0.0 3.6e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFY00719.1 - 0.049 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 KFY00720.1 - 5.9e-112 374.5 27.3 8.8e-112 373.9 18.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00720.1 - 1.4e-15 56.8 38.1 3.9e-11 42.2 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_16 PF13191.1 KFY00720.1 - 1.1e-05 25.5 0.0 3.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFY00720.1 - 1.3e-05 24.9 0.1 3.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain DUF676 PF05057.9 KFY00720.1 - 6.3e-05 22.3 0.9 0.00059 19.1 0.2 2.7 2 1 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFY00720.1 - 0.00021 20.9 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KFY00720.1 - 0.00073 19.4 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family GFA PF04828.9 KFY00720.1 - 0.0014 18.5 0.2 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_5 PF12695.2 KFY00720.1 - 0.0019 17.9 0.1 0.019 14.7 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 KFY00720.1 - 0.015 14.6 0.0 0.042 13.1 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) AAA_22 PF13401.1 KFY00720.1 - 0.022 14.9 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFY00720.1 - 0.064 12.3 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 KaiC Glyco_hydro_92 PF07971.7 KFY00721.1 - 5.2e-166 553.1 0.1 6.7e-166 552.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 AA_permease_2 PF13520.1 KFY00722.1 - 7.7e-83 278.3 45.9 8.5e-83 278.2 31.5 1.2 1 1 0 1 1 1 1 Amino acid permease UCR_Fe-S_N PF10399.4 KFY00722.1 - 0.13 11.4 1.3 0.42 9.8 0.9 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_1 PF07690.11 KFY00723.1 - 2.7e-20 72.4 47.9 4.2e-18 65.1 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY00723.1 - 4.9e-12 45.1 18.3 1.2e-11 43.9 12.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFY00732.1 - 1.9e-09 37.1 1.9 6.2e-09 35.5 0.0 2.7 3 0 0 3 3 3 1 MFS_1 like family Rieske PF00355.21 KFY00739.1 - 4.6e-09 35.7 0.0 6.8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KFY00739.1 - 5.3e-07 29.3 0.0 8.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ribosomal_S6 PF01250.12 KFY00740.1 - 0.38 10.6 4.3 0.25 11.2 0.2 2.8 3 0 0 3 3 3 0 Ribosomal protein S6 DUF2972 PF11186.3 KFY00740.1 - 2.1 8.1 9.3 0.62 9.9 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2972) UvdE PF03851.9 KFY00741.1 - 7.8e-109 362.9 0.0 9.8e-109 362.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE F-box-like PF12937.2 KFY00742.1 - 0.00046 19.8 0.3 0.0011 18.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFY00742.1 - 0.055 13.1 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box domain MtrC PF04211.8 KFY00763.1 - 0.016 14.2 5.5 0.03 13.3 3.8 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Methyltransf_2 PF00891.13 KFY00764.1 - 1.3e-26 93.2 0.0 2.1e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KFY00764.1 - 6.3e-05 22.7 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.1 KFY00765.1 - 2.6e-19 69.4 0.0 4.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY00765.1 - 2.3e-07 30.5 0.0 1.6e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY00765.1 - 2.9e-07 30.8 0.0 9.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00765.1 - 1.3e-06 28.9 0.0 7.6e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY00765.1 - 2.9e-05 24.4 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY00765.1 - 0.0021 18.4 0.0 0.0053 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFY00765.1 - 0.0045 16.9 0.0 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFY00765.1 - 0.012 15.6 0.0 0.043 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFY00765.1 - 0.025 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFY00765.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KFY00765.1 - 0.037 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.2 KFY00766.1 - 1.3e-73 243.3 1.7 1.2e-13 51.1 0.2 8.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFY00766.1 - 7.4e-54 176.9 2.2 7.2e-05 22.3 0.0 13.7 13 0 0 13 13 13 11 Ankyrin repeat Ank_3 PF13606.1 KFY00766.1 - 1.1e-49 161.4 5.0 0.0037 17.3 0.0 13.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KFY00766.1 - 9e-42 140.7 5.9 3.1e-06 27.5 0.1 10.5 8 2 2 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY00766.1 - 5.4e-38 128.1 3.9 1.3e-05 25.2 0.0 12.3 6 3 7 13 13 13 9 Ankyrin repeats (many copies) CorA PF01544.13 KFY00766.1 - 1.4e-07 30.8 0.1 3.9e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Fasciclin PF02469.17 KFY00767.1 - 5.5e-39 133.0 0.0 1.1e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Pyridoxal_deC PF00282.14 KFY00768.1 - 2.2e-58 197.4 0.0 3.1e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFY00768.1 - 1.9e-05 23.6 0.0 3.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_45 PF02015.11 KFY00770.1 - 1.4e-62 211.3 16.6 1.7e-62 211.0 11.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Flavoprotein PF02441.14 KFY00771.1 - 9.4e-38 128.8 0.2 1.3e-37 128.3 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein Zn_clus PF00172.13 KFY00772.1 - 1.6e-08 34.3 5.1 1.6e-08 34.3 3.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY00772.1 - 0.036 12.6 1.1 0.056 12.0 0.8 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain RTA1 PF04479.8 KFY00773.1 - 3.4e-12 46.3 10.7 1.3e-11 44.4 7.4 1.8 1 1 0 1 1 1 1 RTA1 like protein CBM_1 PF00734.13 KFY00774.1 - 3.7e-09 36.0 11.0 7.9e-09 35.0 7.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF605 PF04652.11 KFY00774.1 - 5.9 6.1 20.2 8.3 5.6 14.0 1.1 1 0 0 1 1 1 0 Vta1 like PBP_like_2 PF12849.2 KFY00775.1 - 3.5e-09 36.5 0.3 4.4e-09 36.1 0.2 1.1 1 0 0 1 1 1 1 PBP superfamily domain adh_short PF00106.20 KFY00776.1 - 2.1e-28 99.3 0.0 2.6e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00776.1 - 8.8e-26 91.1 0.0 1.1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00776.1 - 1.1e-10 41.4 0.0 1.6e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFY00776.1 - 3.8e-05 23.3 0.1 0.00015 21.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFY00776.1 - 0.00063 19.2 0.0 0.00087 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFY00776.1 - 0.0048 16.0 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KFY00776.1 - 0.03 13.3 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 KFY00776.1 - 0.041 12.7 0.2 0.049 12.5 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 KFY00776.1 - 0.048 12.8 0.2 2 7.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFY00776.1 - 0.082 13.1 1.1 0.21 11.8 0.8 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF2974 PF11187.3 KFY00776.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HET PF06985.6 KFY00777.1 - 2.5e-11 43.9 0.0 1.6e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFA PF04828.9 KFY00777.1 - 7.2e-11 41.8 0.2 2e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_24 PF13578.1 KFY00778.1 - 1.9e-13 51.1 0.0 3.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFY00778.1 - 1.6e-07 30.6 0.1 8e-07 28.3 0.1 1.9 1 1 0 1 1 1 1 O-methyltransferase WD40 PF00400.27 KFY00779.1 - 3.9e-11 42.3 17.5 3e-05 23.7 0.2 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-RING_2 PF13639.1 KFY00779.1 - 0.02 14.7 8.7 0.045 13.5 6.0 1.6 1 0 0 1 1 1 0 Ring finger domain DUF1275 PF06912.6 KFY00785.1 - 3.6e-44 150.4 9.8 4.7e-44 150.0 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3522 PF12036.3 KFY00785.1 - 0.056 13.2 0.8 0.091 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Bax1-I PF01027.15 KFY00785.1 - 2.2 7.8 12.1 0.14 11.7 2.9 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 KFY00785.1 - 2.4 7.5 9.8 0.1 12.0 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ABC_tran PF00005.22 KFY00786.1 - 9.2e-48 162.0 0.1 1.9e-25 89.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFY00786.1 - 1.2e-15 58.2 3.3 0.0079 16.1 0.1 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KFY00786.1 - 3.7e-12 45.9 0.5 0.0031 16.7 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFY00786.1 - 1.1e-08 35.7 0.1 0.00072 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFY00786.1 - 2e-08 33.6 1.1 0.005 16.3 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFY00786.1 - 3.4e-07 29.6 0.0 0.32 9.9 0.0 3.2 3 0 0 3 3 3 3 AAA ATPase domain DUF258 PF03193.11 KFY00786.1 - 2.3e-06 26.9 0.1 0.0078 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFY00786.1 - 2.8e-06 27.2 0.4 0.15 12.0 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 KFY00786.1 - 2.5e-05 24.0 0.0 0.39 10.6 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KFY00786.1 - 2.7e-05 24.9 0.0 0.33 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFY00786.1 - 6e-05 23.5 0.0 0.028 14.9 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Chromo PF00385.19 KFY00786.1 - 0.0001 21.9 0.2 0.00023 20.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.1 KFY00786.1 - 0.00038 20.4 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFY00786.1 - 0.00095 19.3 0.7 1.4 9.0 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KFY00786.1 - 0.0015 18.0 2.3 1.2 8.4 0.1 3.5 4 0 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 KFY00786.1 - 0.0021 17.9 0.7 0.42 10.3 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_13 PF13166.1 KFY00786.1 - 0.0031 16.0 0.1 1 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFY00786.1 - 0.0091 16.3 0.1 2.1 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KFY00786.1 - 0.0091 15.8 0.0 0.6 9.9 0.0 3.0 3 0 0 3 3 3 1 Dynamin family HEAT_2 PF13646.1 KFY00786.1 - 0.01 16.0 5.6 0.94 9.8 0.1 3.6 1 1 2 3 3 3 0 HEAT repeats PduV-EutP PF10662.4 KFY00786.1 - 0.017 14.6 0.1 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KFY00786.1 - 0.023 14.5 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFY00786.1 - 0.038 14.1 0.0 10 6.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase DUF3584 PF12128.3 KFY00786.1 - 0.039 11.3 2.6 1.7 5.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ArgK PF03308.11 KFY00786.1 - 0.043 12.5 0.7 4 6.1 0.0 2.4 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 KFY00786.1 - 0.043 13.4 0.5 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 KFY00786.1 - 0.066 12.1 0.1 7.8 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KFY00786.1 - 0.098 11.7 0.3 11 5.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFY00786.1 - 0.1 12.2 0.3 17 5.1 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KFY00786.1 - 0.14 11.5 1.5 4.3 6.7 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 KFY00786.1 - 0.27 9.7 3.6 22 3.4 0.0 3.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ALF PF03752.8 KFY00786.1 - 0.66 9.8 3.7 1.7 8.5 1.5 2.3 2 0 0 2 2 2 0 Short repeats of unknown function HEAT PF02985.17 KFY00786.1 - 0.9 9.7 7.4 62 4.0 0.0 5.0 5 0 0 5 5 4 0 HEAT repeat HET PF06985.6 KFY00787.1 - 4.3e-21 75.5 0.0 7.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Scm3 PF10384.4 KFY00787.1 - 0.0087 15.5 0.2 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 adh_short PF00106.20 KFY00788.1 - 1.7e-27 96.3 2.8 2.3e-27 95.9 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00788.1 - 2.4e-17 63.5 0.0 3.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00788.1 - 2e-09 37.3 1.7 3e-09 36.7 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFY00788.1 - 0.00015 21.4 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 KFY00788.1 - 0.00058 20.2 0.0 0.0013 19.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00788.1 - 0.0012 19.4 0.0 0.01 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KFY00788.1 - 0.0034 16.8 0.1 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFY00788.1 - 0.0046 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.1 KFY00788.1 - 0.064 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KFY00788.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPMT PF05724.6 KFY00788.1 - 0.097 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MoaC PF01967.16 KFY00788.1 - 0.1 12.2 0.3 0.59 9.7 0.0 2.1 1 1 1 2 2 2 0 MoaC family Eno-Rase_NADH_b PF12242.3 KFY00788.1 - 0.2 11.4 1.5 0.93 9.3 0.1 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gln-synt_C PF00120.19 KFY00789.1 - 7e-63 212.1 0.0 9.4e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SKG6 PF08693.5 KFY00791.1 - 1.1e-09 37.4 0.2 2.2e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glyco_tranf_2_4 PF13704.1 KFY00794.1 - 1.7e-10 41.0 1.5 3.1e-10 40.2 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 KFY00794.1 - 1.2e-07 31.3 0.7 3.5e-07 29.8 0.5 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 Citrate_synt PF00285.16 KFY00795.1 - 5.9e-100 334.4 0.0 7e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 KFY00796.1 - 1.5e-198 660.3 0.1 1.7e-198 660.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFY00796.1 - 2.9e-11 43.0 0.1 1.8e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KFY00796.1 - 0.036 13.5 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF2458 PF10454.4 KFY00796.1 - 0.14 12.0 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Glyco_hydro_61 PF03443.9 KFY00797.1 - 3.9e-70 236.0 0.6 4.6e-70 235.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fibrinogen_C PF00147.13 KFY00797.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Hydrophobin PF01185.13 KFY00798.1 - 1.6e-07 31.6 13.2 1.6e-07 31.6 9.2 1.8 2 1 0 2 2 2 1 Fungal hydrophobin Pkinase PF00069.20 KFY00805.1 - 1.8e-31 109.2 0.0 4.4e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00805.1 - 5.8e-12 45.2 0.0 0.00021 20.4 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KFY00805.1 - 0.0055 16.4 0.0 0.044 13.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family HAD PF12710.2 KFY00806.1 - 5.2e-13 49.5 0.0 1.2e-12 48.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFY00806.1 - 1.3e-12 47.2 0.8 3e-11 42.8 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFY00806.1 - 1.3e-12 47.4 0.0 5.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFY00806.1 - 8.7e-12 45.9 1.7 3.4e-10 40.7 1.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY00806.1 - 0.0087 15.6 0.3 0.026 14.1 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PX PF00787.19 KFY00807.1 - 6.4e-21 74.2 1.2 7.6e-21 74.0 0.1 1.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFY00807.1 - 7.3e-10 38.4 9.5 7.4e-05 22.1 0.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KFY00807.1 - 0.01 15.3 4.5 0.034 13.6 3.1 1.8 1 1 0 1 1 1 0 BAR domain DUF3140 PF11338.3 KFY00807.1 - 0.061 13.4 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Occludin_ELL PF07303.8 KFY00807.1 - 0.09 13.5 0.6 9.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Occludin homology domain FlaC_arch PF05377.6 KFY00807.1 - 0.9 9.4 3.9 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) hGDE_N PF14699.1 KFY00808.1 - 0.05 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme SKG6 PF08693.5 KFY00809.1 - 0.0017 17.6 0.6 0.0017 17.6 0.4 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EVI2A PF05399.6 KFY00809.1 - 0.05 12.8 4.6 0.086 12.0 3.2 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF347 PF03988.7 KFY00809.1 - 0.11 12.3 0.1 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Pex16 PF08610.5 KFY00809.1 - 0.11 11.4 1.5 0.16 10.9 1.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TFIIA PF03153.8 KFY00809.1 - 0.22 11.3 5.8 0.28 11.0 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LETM1 PF07766.8 KFY00810.1 - 8.2e-106 352.9 0.2 1.3e-105 352.2 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KFY00810.1 - 7.2e-06 25.3 0.0 0.0015 17.9 0.0 3.0 3 0 0 3 3 3 2 SAP domain V_ATPase_I PF01496.14 KFY00810.1 - 1 7.1 3.1 16 3.1 3.3 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YchF-GTPase_C PF06071.8 KFY00812.1 - 8.2e-37 124.8 0.2 2.3e-36 123.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KFY00812.1 - 0.017 15.0 0.1 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Transposase_mut PF00872.13 KFY00812.1 - 0.13 10.7 0.0 2.3 6.7 0.0 2.0 1 1 1 2 2 2 0 Transposase, Mutator family MMR_HSR1 PF01926.18 KFY00813.1 - 7.5e-11 42.0 0.0 9.6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFY00813.1 - 7.1e-08 31.8 0.0 8.3e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_10 PF12846.2 KFY00813.1 - 0.096 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain OPT PF03169.10 KFY00814.1 - 2.5e-90 303.7 44.5 2.9e-90 303.5 30.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_tr PF00083.19 KFY00815.1 - 1.8e-92 310.2 27.8 2.3e-92 309.9 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00815.1 - 1.6e-34 119.1 42.4 4.9e-30 104.4 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.1 KFY00815.1 - 1.3e-06 28.5 0.1 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFY00815.1 - 0.007 16.2 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFY00815.1 - 0.0071 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFY00815.1 - 0.016 15.2 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBM_1 PF00734.13 KFY00816.1 - 4.4e-14 51.8 6.9 9.4e-14 50.7 4.8 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 KFY00816.1 - 9.5e-14 51.9 2.8 2.2e-13 50.7 1.9 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY00816.1 - 4.8e-08 33.1 0.6 7.4e-08 32.5 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFY00816.1 - 0.053 13.2 0.1 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family PTR2 PF00854.16 KFY00818.1 - 6.3e-40 137.1 11.1 1.6e-39 135.7 7.7 1.7 1 1 0 1 1 1 1 POT family FAD_binding_4 PF01565.18 KFY00819.1 - 5.8e-21 74.4 0.3 1.3e-20 73.2 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY00819.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydro_2_N PF02837.13 KFY00820.1 - 7.7e-35 119.9 0.0 1.2e-33 116.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFY00820.1 - 4e-30 104.7 0.0 1.3e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFY00820.1 - 3.4e-16 59.6 0.3 7.1e-16 58.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFY00820.1 - 0.00019 21.6 0.1 0.011 16.0 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain adh_short PF00106.20 KFY00821.1 - 1.9e-21 76.6 0.0 2.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00821.1 - 6.4e-12 45.7 0.0 7.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFY00821.1 - 0.00058 19.9 0.0 0.0025 17.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KFY00821.1 - 0.0011 18.6 0.2 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 KFY00821.1 - 0.0037 16.9 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KFY00821.1 - 0.066 13.6 0.1 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KFY00821.1 - 0.16 10.8 0.0 0.16 10.8 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DSBA PF01323.15 KFY00822.1 - 2.1e-16 60.0 0.0 2.4e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Lactococcin PF04369.8 KFY00822.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family NAD_binding_8 PF13450.1 KFY00825.1 - 2.5e-14 53.0 0.0 6.4e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY00825.1 - 5.7e-05 22.1 0.2 0.00086 18.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFY00825.1 - 0.00013 21.1 0.0 0.00029 20.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KFY00825.1 - 0.0002 21.1 0.3 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFY00825.1 - 0.0033 17.3 0.0 0.017 14.9 0.0 2.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFY00825.1 - 0.0048 15.7 0.1 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KFY00825.1 - 0.0082 14.8 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 KFY00825.1 - 0.032 14.6 0.3 0.39 11.1 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY00825.1 - 0.035 12.5 0.1 0.3 9.4 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.12 KFY00825.1 - 0.081 12.0 0.1 0.19 10.8 0.0 1.7 1 1 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KFY00825.1 - 0.1 11.4 1.5 0.55 9.0 0.0 2.3 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) ADH_zinc_N_2 PF13602.1 KFY00826.1 - 1.8e-21 77.3 1.1 3.5e-21 76.4 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFY00826.1 - 1.7e-14 53.4 0.0 4.3e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KFY00826.1 - 0.0031 17.5 0.1 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Sugar_tr PF00083.19 KFY00827.1 - 3.6e-75 253.2 23.2 4.4e-75 252.9 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00827.1 - 5.3e-29 101.0 28.4 9.2e-20 70.6 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PNP_UDP_1 PF01048.15 KFY00835.1 - 1.4e-05 24.2 0.0 3.6e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily zf-C3HC4_3 PF13920.1 KFY00836.1 - 2.3e-07 30.3 3.8 4.7e-07 29.3 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY00836.1 - 1.8e-06 27.8 8.4 4.3e-06 26.6 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 KFY00836.1 - 2.8e-06 26.8 2.3 2.8e-06 26.8 1.6 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 KFY00836.1 - 4.4e-06 26.3 7.2 9.1e-06 25.3 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFY00836.1 - 8.9e-06 25.2 6.5 1.9e-05 24.2 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY00836.1 - 1.1e-05 25.1 6.4 3.1e-05 23.6 4.4 1.9 1 0 0 1 1 1 1 Ring finger domain CorA PF01544.13 KFY00836.1 - 5.8e-05 22.2 3.4 0.00012 21.2 2.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-RING_UBOX PF13445.1 KFY00836.1 - 0.00022 20.8 2.0 0.00062 19.4 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFY00836.1 - 0.0077 16.0 6.5 0.018 14.8 4.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2207 PF09972.4 KFY00836.1 - 0.17 10.4 0.2 0.31 9.5 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PrgI PF12666.2 KFY00836.1 - 0.51 10.5 2.2 0.84 9.8 0.8 1.8 2 0 0 2 2 2 0 PrgI family protein zf-PARP PF00645.13 KFY00851.1 - 7.8e-19 67.7 0.1 1.9e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Amidase PF01425.16 KFY00852.1 - 6.7e-74 249.3 0.4 3.2e-72 243.8 0.3 2.1 1 1 0 1 1 1 1 Amidase HypD PF01924.11 KFY00873.1 - 0.0022 16.7 1.4 2.3 6.8 0.0 3.2 2 1 1 3 3 3 2 Hydrogenase formation hypA family zf-ZPR1 PF03367.8 KFY00873.1 - 0.033 13.3 10.0 14 4.8 0.1 5.0 5 0 0 5 5 5 0 ZPR1 zinc-finger domain Plasmid_stab_B PF10784.4 KFY00873.1 - 6 6.5 12.5 24 4.6 0.1 4.5 4 0 0 4 4 4 0 Plasmid stability protein MAPEG PF01124.13 KFY00883.1 - 3.4e-22 78.4 1.4 4e-22 78.1 1.0 1.1 1 0 0 1 1 1 1 MAPEG family DUF2428 PF10350.4 KFY00884.1 - 2.7e-62 210.1 0.2 9.2e-62 208.3 0.0 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KFY00884.1 - 0.0026 17.6 1.3 7.8 6.8 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat TEX15 PF15326.1 KFY00884.1 - 0.0036 16.9 1.4 0.01 15.5 0.7 1.9 2 0 0 2 2 2 1 Testis expressed sequence 15 Tim17 PF02466.14 KFY00885.1 - 1.4e-26 93.0 4.0 1.8e-26 92.6 2.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2276 PF10040.4 KFY00885.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2276) UCH PF00443.24 KFY00886.1 - 6.1e-75 251.7 0.0 2.6e-74 249.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFY00886.1 - 1.8e-13 50.6 0.0 7.5e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFY00886.1 - 2.2e-07 31.2 0.0 5.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 DUSP domain DDOST_48kD PF03345.9 KFY00903.1 - 4.8e-163 542.5 0.0 5.4e-163 542.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta SRR1 PF07985.7 KFY00905.1 - 9.4e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 KFY00905.1 - 0.067 13.2 2.4 0.12 12.4 1.6 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) adh_short PF00106.20 KFY00906.1 - 4.2e-23 82.0 2.1 6.5e-23 81.4 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00906.1 - 7.4e-14 52.1 0.2 9.9e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00906.1 - 3.8e-06 26.6 0.7 6.3e-06 25.9 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY00906.1 - 5e-06 26.6 0.5 9e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KFY00906.1 - 0.0038 16.7 0.3 0.0083 15.6 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KFY00906.1 - 0.0048 16.3 0.5 0.014 14.8 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exo_endo_phos PF03372.18 KFY00907.1 - 5.4e-20 72.3 0.1 6.9e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-DHHC PF01529.15 KFY00912.1 - 6.5e-33 113.5 1.5 6.5e-33 113.5 1.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Jacalin PF01419.12 KFY00913.1 - 0.1 12.4 0.1 0.25 11.2 0.0 1.9 1 1 0 1 1 1 0 Jacalin-like lectin domain Acetyltransf_1 PF00583.19 KFY00914.1 - 1.9e-11 43.8 1.6 7.9e-11 41.8 1.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFY00914.1 - 3.6e-11 43.1 0.4 8.4e-08 32.3 0.1 2.2 1 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFY00914.1 - 6.9e-09 35.7 0.1 2.5e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFY00914.1 - 0.00011 22.0 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY00914.1 - 0.00021 21.0 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KFY00914.1 - 0.0047 16.8 0.0 0.032 14.0 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DHquinase_I PF01487.10 KFY00915.1 - 5.8e-33 114.4 0.0 8.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KFY00915.1 - 2.5e-17 63.1 0.0 5.2e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 KFY00915.1 - 3.1e-13 49.5 0.1 6.6e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFY00915.1 - 1e-12 48.3 0.0 2.8e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KFY00915.1 - 0.059 13.1 0.3 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 KFY00916.1 - 4.5e-21 74.9 0.3 7.8e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00916.1 - 3.1e-08 33.3 11.4 5.2e-08 32.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFY00925.1 - 4.8e-121 404.4 24.6 5.5e-121 404.2 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00925.1 - 2.1e-20 72.7 28.6 2.1e-20 72.7 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3154 PF11351.3 KFY00925.1 - 0.6 9.8 5.2 1 9.1 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) DUF261 PF03196.8 KFY00925.1 - 0.67 9.9 3.2 0.44 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF261 HR1 PF02185.11 KFY00926.1 - 0.00088 18.9 0.6 0.0016 18.1 0.4 1.4 1 0 0 1 1 1 1 Hr1 repeat Tropomyosin PF00261.15 KFY00926.1 - 0.0042 16.2 2.7 0.007 15.4 1.9 1.3 1 0 0 1 1 1 1 Tropomyosin DUF4482 PF14818.1 KFY00926.1 - 0.019 15.5 2.2 4.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) DUF2096 PF09869.4 KFY00926.1 - 0.08 12.8 0.4 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) SlyX PF04102.7 KFY00926.1 - 0.2 12.0 5.0 12 6.3 0.1 3.1 2 1 1 3 3 3 0 SlyX Abhydrolase_9 PF10081.4 KFY00926.1 - 0.22 10.2 0.9 0.36 9.4 0.6 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Nse4_C PF08743.5 KFY00932.1 - 2.1e-34 117.4 0.0 3.3e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Nse4 C-terminal GRA6 PF05084.8 KFY00937.1 - 0.28 10.6 2.5 0.29 10.6 1.8 1.1 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DNA_pol_A PF00476.15 KFY00938.1 - 5.2e-102 341.3 0.0 8.4e-102 340.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Ribosomal_L16 PF00252.13 KFY00939.1 - 1.5e-30 105.6 0.6 2e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C3HC4_3 PF13920.1 KFY00940.1 - 2.1e-11 43.2 5.6 3.2e-11 42.7 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY00940.1 - 5.7e-10 38.8 8.1 9.3e-10 38.1 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFY00940.1 - 1.3e-08 34.3 6.5 2e-08 33.7 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY00940.1 - 1.5e-08 34.5 7.7 2.3e-08 33.9 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY00940.1 - 1.3e-07 31.1 7.5 2.1e-07 30.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFY00940.1 - 0.00014 21.3 4.3 0.00024 20.5 3.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFY00940.1 - 0.0018 18.0 0.9 0.0032 17.2 0.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFY00940.1 - 0.0021 17.8 3.1 0.0036 17.1 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFY00940.1 - 0.0038 17.0 6.8 0.0075 16.1 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFY00940.1 - 0.004 16.8 5.7 0.0056 16.3 2.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 KFY00940.1 - 0.05 13.3 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 KFY00940.1 - 0.23 11.5 5.5 0.59 10.2 3.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-UDP PF14569.1 KFY00940.1 - 0.51 10.1 2.7 1.5 8.6 1.9 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger UPF0547 PF10571.4 KFY00940.1 - 0.62 9.7 4.4 8.6 6.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_4 PF14447.1 KFY00940.1 - 8.8 5.9 8.5 27 4.4 5.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 UPF0052 PF01933.13 KFY00941.1 - 1.2e-51 175.8 0.0 1.5e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PI3_PI4_kinase PF00454.22 KFY00942.1 - 1.6e-48 165.1 0.0 3.4e-48 164.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KFY00942.1 - 1e-32 113.0 2.5 2e-32 112.0 0.1 2.8 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KFY00942.1 - 1.1e-11 43.9 0.1 3.9e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 FATC domain DUF3414 PF11894.3 KFY00943.1 - 0 1349.7 17.1 0 1349.4 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 KFY00944.1 - 1.7e-124 416.5 2.6 2.4e-124 416.0 1.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFY00944.1 - 6.9e-26 89.8 0.7 2e-25 88.3 0.5 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_34 PF13601.1 KFY00944.1 - 0.046 13.7 0.4 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Glyco_hydro_28 PF00295.12 KFY00945.1 - 5.2e-86 288.5 18.6 7.2e-86 288.0 12.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Catalase PF00199.14 KFY00946.1 - 6e-162 538.6 0.6 7.6e-162 538.3 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFY00946.1 - 1.6e-17 63.1 0.0 4.1e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KFY00946.1 - 2e-10 40.2 0.1 4.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFY00946.1 - 1.3e-06 27.8 0.0 2.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase LUC7 PF03194.10 KFY00947.1 - 6.7e-69 232.2 0.2 6.7e-69 232.2 0.1 2.8 3 0 0 3 3 3 1 LUC7 N_terminus Abi_2 PF07751.6 KFY00947.1 - 0.033 14.3 0.3 0.033 14.3 0.2 2.5 2 0 0 2 2 2 0 Abi-like protein Gpi16 PF04113.9 KFY00948.1 - 6e-233 773.9 0.0 7.7e-233 773.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF4066 PF13278.1 KFY00949.1 - 3.2e-21 75.3 0.0 4.7e-18 65.0 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KFY00949.1 - 1.1e-07 31.3 0.0 2.8e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4123 PF13503.1 KFY00949.1 - 0.15 12.0 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) zf-HC5HC2H_2 PF13832.1 KFY00965.1 - 6.9e-33 112.9 8.6 6.9e-33 112.9 6.0 2.7 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFY00965.1 - 2e-26 91.9 8.5 2e-26 91.9 5.9 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 KFY00965.1 - 5.4e-22 78.7 0.0 3.3e-21 76.1 0.0 2.4 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 KFY00965.1 - 9.4e-15 53.6 2.1 2.6e-14 52.2 1.4 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.24 KFY00965.1 - 1e-08 34.7 24.1 8e-08 31.8 6.7 2.8 2 0 0 2 2 2 2 PHD-finger DUF1620 PF07774.8 KFY00972.1 - 3.9e-25 88.3 0.0 1.1e-24 86.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ PF01011.16 KFY00972.1 - 5.4e-06 25.6 2.7 0.29 10.7 0.0 5.0 5 0 0 5 5 5 3 PQQ enzyme repeat PQQ_3 PF13570.1 KFY00972.1 - 0.00028 21.0 2.7 0.016 15.4 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain CNH PF00780.17 KFY00973.1 - 6.6e-73 245.4 0.0 9.8e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KFY00973.1 - 1.9e-27 96.3 0.7 3.6e-27 95.3 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KFY00973.1 - 6e-14 52.1 0.1 4.1e-13 49.4 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFY00973.1 - 5.2e-05 23.3 0.0 0.0002 21.4 0.0 2.1 2 0 0 2 2 2 1 PH domain CBFD_NFYB_HMF PF00808.18 KFY00988.1 - 5e-10 39.2 0.0 9.3e-10 38.4 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFY00988.1 - 2.5e-07 30.6 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFY00988.1 - 0.0083 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated PPE PF00823.14 KFY00988.1 - 0.013 15.3 0.2 0.018 14.8 0.2 1.2 1 0 0 1 1 1 0 PPE family CENP-S PF15630.1 KFY00988.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S SLD3 PF08639.5 KFY00989.1 - 4.2e-94 315.9 7.2 4.2e-94 315.9 5.0 1.7 2 1 0 2 2 2 1 DNA replication regulator SLD3 zf-H2C2_2 PF13465.1 KFY00992.1 - 1.1e-13 50.7 10.0 8.8e-08 32.0 0.3 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFY00992.1 - 1.9e-11 43.5 12.6 7.8e-06 25.9 1.6 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY00992.1 - 1.1e-10 41.0 12.8 3.7e-05 23.7 1.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFY00992.1 - 5.7e-07 29.5 4.7 0.029 14.5 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFY00992.1 - 4.2e-05 23.5 2.3 0.013 15.6 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFY00992.1 - 0.03 14.4 2.2 0.085 13.0 1.5 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 KFY00992.1 - 5 7.2 7.8 15 5.7 2.7 2.9 2 1 1 3 3 3 0 LIM domain DNA_pol_E_B PF04042.11 KFY01008.1 - 5.5e-46 156.4 0.0 8.1e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PRELI PF04707.9 KFY01010.1 - 7.1e-24 84.1 0.0 5.6e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.20 KFY01011.1 - 1.2e-19 70.5 0.0 2.8e-19 69.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MRP-L20 PF12824.2 KFY01018.1 - 4.3e-58 195.9 3.2 4.9e-58 195.7 2.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Tyr_Deacylase PF02580.11 KFY01019.1 - 6.5e-45 152.6 0.3 7.3e-45 152.5 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Aminotran_4 PF01063.14 KFY01020.1 - 3.3e-27 95.4 0.0 5.3e-27 94.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class IV Claudin_2 PF13903.1 KFY01022.1 - 0.001 18.8 3.1 0.0016 18.1 2.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction HSP70 PF00012.15 KFY01039.1 - 7e-268 889.5 5.1 7.9e-268 889.3 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFY01039.1 - 4.7e-17 61.5 0.0 7.9e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFY01039.1 - 0.0026 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFY01039.1 - 0.0052 16.6 1.7 0.98 9.2 0.1 3.3 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 KFY01039.1 - 0.01 14.9 0.1 0.039 13.0 0.0 1.9 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.6 KFY01039.1 - 0.053 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 StbA protein E1-E2_ATPase PF00122.15 KFY01040.1 - 1.6e-48 164.7 2.1 2.1e-48 164.3 0.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase PP2C PF00481.16 KFY01040.1 - 2.4e-31 109.0 0.0 3.4e-26 92.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Cation_ATPase_C PF00689.16 KFY01040.1 - 1.4e-29 102.9 6.3 1.4e-29 102.9 4.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFY01040.1 - 6.4e-29 101.9 0.0 5.8e-28 98.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY01040.1 - 1.1e-15 57.3 0.0 2.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFY01040.1 - 2.6e-15 57.0 0.0 1.2e-14 54.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFY01040.1 - 3.5e-12 45.5 0.0 7.4e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFY01040.1 - 0.00098 18.7 0.1 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 KFY01040.1 - 0.025 14.8 2.2 0.068 13.5 0.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) PP2C_2 PF13672.1 KFY01040.1 - 0.044 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C DUF2207 PF09972.4 KFY01040.1 - 6.6 5.1 5.2 9.6 4.6 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF3844 PF12955.2 KFY01057.1 - 7.1e-31 106.3 2.3 7.1e-31 106.3 1.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) GNAT_acetyltr_2 PF13718.1 KFY01058.1 - 1.1e-78 263.1 0.0 2.1e-78 262.1 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KFY01058.1 - 1.6e-65 220.0 0.0 4.8e-65 218.4 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KFY01058.1 - 2e-40 136.3 0.0 4.8e-40 135.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KFY01058.1 - 2.8e-35 120.4 0.3 8.3e-35 118.9 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Histone PF00125.19 KFY01058.1 - 0.049 13.7 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Acetyltransf_7 PF13508.1 KFY01058.1 - 0.053 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 KFY01059.1 - 0.06 12.0 0.2 7.7 5.0 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 90 Lipase_3 PF01764.20 KFY01060.1 - 2.6e-32 111.3 0.0 3.8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KFY01060.1 - 0.0031 17.2 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFY01060.1 - 0.0053 17.0 0.1 0.0077 16.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFY01060.1 - 0.011 15.6 0.2 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family NmrA PF05368.8 KFY01061.1 - 4.2e-12 45.8 0.0 1e-05 24.9 0.0 2.4 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KFY01061.1 - 0.016 15.2 0.2 0.57 10.1 0.0 2.6 3 0 0 3 3 3 0 NADH(P)-binding Cellulase PF00150.13 KFY01062.1 - 2.1e-49 168.2 0.0 2.7e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) XLF PF09302.6 KFY01063.1 - 3.2e-25 88.8 0.2 3.2e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 XLF (XRCC4-like factor) DUF3807 PF12720.2 KFY01064.1 - 1.2e-28 100.4 6.4 1.7e-28 99.9 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Fork_head PF00250.13 KFY01065.1 - 5.2e-14 52.0 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 KFY01066.1 - 4.7e-65 218.4 8.5 7.5e-65 217.7 5.9 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KFY01066.1 - 1.6e-55 186.0 5.5 2.5e-55 185.3 3.8 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein TPR_20 PF14561.1 KFY01066.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1087 PF06465.8 KFY01066.1 - 0.029 14.2 3.8 0.7 9.8 0.4 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF1662 PF07878.6 KFY01066.1 - 0.13 11.9 0.3 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) YolD PF08863.5 KFY01066.1 - 0.2 11.5 3.2 0.2 11.5 0.1 2.3 2 1 0 2 2 2 0 YolD-like protein Atg14 PF10186.4 KFY01067.1 - 1.9e-19 69.7 0.2 4.4e-19 68.5 0.2 1.6 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFY01067.1 - 5.6e-10 38.7 0.0 1.5e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Autophagy protein Apg6 ALIX_LYPXL_bnd PF13949.1 KFY01067.1 - 0.0042 16.1 2.4 0.0042 16.1 1.7 1.4 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CM_2 PF01817.16 KFY01067.1 - 0.22 11.6 5.8 0.06 13.4 0.6 2.3 1 1 1 2 2 2 0 Chorismate mutase type II NTR2 PF15458.1 KFY01070.1 - 7.3e-64 215.4 21.4 1.2e-63 214.6 14.8 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Myotub-related PF06602.9 KFY01070.1 - 0.097 11.4 0.7 0.16 10.7 0.5 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain LSM PF01423.17 KFY01071.1 - 3e-19 68.3 0.7 3.5e-19 68.1 0.5 1.0 1 0 0 1 1 1 1 LSM domain Thiolase_N PF00108.18 KFY01072.1 - 9.1e-101 336.2 1.2 1.1e-100 335.9 0.5 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFY01072.1 - 1.5e-46 156.8 1.5 1.5e-46 156.8 1.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFY01072.1 - 1.6e-05 24.5 1.2 2.5e-05 23.8 0.4 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFY01072.1 - 0.3 10.7 2.3 1.1 8.9 0.0 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 KFY01073.1 - 7.1e-43 146.2 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFY01073.1 - 2.1e-24 85.3 0.0 6e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KFY01073.1 - 4e-17 61.8 0.0 1.1e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFY01073.1 - 1.6e-09 37.7 0.0 4.7e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFY01073.1 - 1.1e-06 28.3 0.0 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KFY01073.1 - 1.2e-05 25.2 0.1 2.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFY01073.1 - 0.0026 18.2 0.0 0.0076 16.7 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFY01073.1 - 0.05 12.8 0.1 0.16 11.1 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_N PF08240.7 KFY01074.1 - 4.1e-27 94.1 2.5 4.3e-27 94.0 0.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KFY01074.1 - 1.9e-07 30.5 0.9 4.1e-07 29.5 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KFY01074.1 - 2e-05 24.1 0.0 0.0065 16.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase CPSase_sm_chain PF00988.17 KFY01082.1 - 6.4e-26 90.3 0.0 1.2e-25 89.5 0.0 1.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Leader_CPA1 PF08252.6 KFY01082.1 - 1.4e-14 52.8 0.3 3e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide ADH_N PF08240.7 KFY01083.1 - 7.5e-27 93.2 1.8 1.1e-26 92.7 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY01083.1 - 1.7e-16 59.9 0.2 4e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KFY01083.1 - 0.0088 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFY01083.1 - 0.069 12.5 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1253 PF06862.7 KFY01083.1 - 0.2 10.0 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Methyltransf_31 PF13847.1 KFY01089.1 - 3.1e-13 49.5 0.0 4.7e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFY01089.1 - 6.7e-12 45.1 0.0 8.1e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KFY01089.1 - 5e-10 39.9 0.0 1.1e-09 38.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY01089.1 - 6.8e-10 39.0 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01089.1 - 1.5e-08 35.0 0.0 3e-08 34.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFY01089.1 - 3.4e-07 29.2 0.1 4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KFY01089.1 - 8.9e-07 28.4 0.1 1.2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFY01089.1 - 1.2e-06 28.3 0.0 2e-06 27.5 0.0 1.4 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 KFY01089.1 - 6.2e-06 25.4 0.1 7.2e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KFY01089.1 - 2.3e-05 24.6 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY01089.1 - 2.6e-05 24.6 0.0 4.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFY01089.1 - 5.9e-05 23.1 0.0 8.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFY01089.1 - 0.00029 20.3 0.1 0.00035 20.0 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 KFY01089.1 - 0.0013 18.3 0.1 0.0018 17.8 0.1 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PRMT5 PF05185.11 KFY01089.1 - 0.0018 17.3 0.0 0.0023 16.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.14 KFY01089.1 - 0.0031 17.0 0.1 0.0044 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KFY01089.1 - 0.007 15.7 0.1 0.0091 15.3 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Met_10 PF02475.11 KFY01089.1 - 0.0073 15.9 0.1 0.0095 15.5 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.1 KFY01089.1 - 0.0091 15.6 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFY01089.1 - 0.013 14.5 0.1 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 KFY01089.1 - 0.015 14.5 0.3 0.021 13.9 0.2 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 KFY01089.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 KFY01089.1 - 0.044 14.6 0.0 0.069 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KFY01089.1 - 0.071 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_2 PF00891.13 KFY01089.1 - 0.082 12.0 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Per1 PF04080.8 KFY01090.1 - 9.7e-106 353.0 6.8 1.2e-105 352.7 4.7 1.1 1 0 0 1 1 1 1 Per1-like DEAD PF00270.24 KFY01091.1 - 1.8e-44 151.2 0.0 2.6e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY01091.1 - 2.2e-26 91.5 0.0 4.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY01091.1 - 0.0019 18.0 0.0 0.0066 16.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.13 KFY01092.1 - 2.1e-57 193.8 0.0 2.9e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pox_Ag35 PF03286.9 KFY01092.1 - 1.1 8.6 12.0 2.4 7.6 8.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 KFY01099.1 - 4.6e-230 764.8 0.1 1.5e-229 763.2 0.1 2.3 1 1 0 1 1 1 1 CDC45-like protein MFS_1 PF07690.11 KFY01100.1 - 1.7e-19 69.7 29.9 4.2e-19 68.4 20.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily YlaH PF14036.1 KFY01100.1 - 0.48 10.5 4.1 1.2 9.2 1.7 2.3 2 0 0 2 2 2 0 YlaH-like protein adh_short PF00106.20 KFY01101.1 - 1.1e-21 77.4 0.1 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY01101.1 - 3.3e-07 30.1 0.0 5.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFY01101.1 - 0.0004 20.2 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-grasp_5 PF13549.1 KFY01101.1 - 0.064 12.4 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Reprolysin_5 PF13688.1 KFY01102.1 - 0.0047 16.8 0.2 0.0066 16.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFY01102.1 - 0.027 15.0 0.6 0.069 13.6 0.4 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MAD PF05557.8 KFY01120.1 - 2.4e-48 164.7 57.7 3.6e-47 160.9 40.0 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Intimin_C PF07979.6 KFY01120.1 - 0.14 12.4 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 Intimin C-type lectin domain YqjK PF13997.1 KFY01120.1 - 0.42 10.8 4.1 6 7.1 0.0 3.4 3 0 0 3 3 3 0 YqjK-like protein IL2 PF00715.12 KFY01120.1 - 0.67 9.6 4.1 0.39 10.4 0.2 2.6 3 0 0 3 3 3 0 Interleukin 2 DUF2316 PF10078.4 KFY01120.1 - 3.4 7.7 13.2 1.5 8.8 0.9 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) UQ_con PF00179.21 KFY01122.1 - 4.1e-09 35.9 0.0 7.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY01122.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF1014 PF06244.7 KFY01123.1 - 1.4e-19 70.5 10.2 3.7e-19 69.1 7.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) TEX19 PF15553.1 KFY01123.1 - 5.8 6.7 6.2 4.2 7.2 1.1 2.1 2 0 0 2 2 2 0 Testis-expressed protein 19 Tcp11 PF05794.8 KFY01132.1 - 5e-65 219.9 0.1 1.8e-64 218.1 0.0 1.8 2 0 0 2 2 2 1 T-complex protein 11 HAUS6_N PF14661.1 KFY01132.1 - 0.73 9.1 8.9 2.6 7.3 6.2 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-B_dimeris PF09026.5 KFY01133.1 - 0.16 12.2 3.9 0.23 11.6 2.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Polyketide_cyc2 PF10604.4 KFY01134.1 - 6.5e-07 29.5 1.2 9.9e-07 29.0 0.9 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KFY01134.1 - 0.014 15.3 0.1 0.022 14.7 0.1 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport POR_N PF01855.14 KFY01135.1 - 0.6 9.5 4.5 0.94 8.9 3.1 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Abhydrolase_5 PF12695.2 KFY01136.1 - 3.2e-17 62.6 0.1 5.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KFY01136.1 - 3.9e-12 45.1 0.0 5.4e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KFY01136.1 - 2e-09 37.6 0.5 3.4e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFY01136.1 - 2.3e-06 26.7 0.0 4.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 KFY01136.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KFY01136.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 KFY01136.1 - 0.027 14.3 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase DLH PF01738.13 KFY01136.1 - 0.039 13.2 0.0 0.068 12.4 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase PF07224.6 KFY01136.1 - 0.056 12.2 0.1 0.81 8.4 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.16 KFY01136.1 - 0.23 10.6 0.7 1.5 7.9 0.2 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.6 KFY01137.1 - 4.5e-22 78.6 5.1 6.6e-19 68.4 0.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_71 PF03659.9 KFY01138.1 - 2.6e-59 200.6 1.2 4.4e-59 199.8 0.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 MFS_1 PF07690.11 KFY01139.1 - 1.9e-27 95.8 52.6 4.4e-15 55.2 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY01139.1 - 4.9e-08 31.9 27.7 3.4e-05 22.6 9.3 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3040 PF11239.3 KFY01141.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SET PF00856.23 KFY01142.1 - 3.8e-12 46.8 0.0 6.8e-11 42.7 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 KFY01142.1 - 1.5e-06 27.7 1.4 0.00035 20.1 0.0 3.7 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 KFY01142.1 - 0.00046 19.8 2.4 0.094 12.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFY01142.1 - 0.0015 18.8 0.4 0.13 12.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFY01142.1 - 0.019 15.5 2.8 4.2 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_12 PF13087.1 KFY01143.1 - 2.7e-19 69.3 0.0 5.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFY01143.1 - 8.9e-13 48.3 0.0 2e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFY01143.1 - 8.6e-06 25.4 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFY01143.1 - 0.0028 17.3 0.0 0.01 15.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KFY01143.1 - 0.0051 16.3 0.2 10 5.5 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KFY01143.1 - 0.033 13.5 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFY01143.1 - 0.082 13.0 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFY01143.1 - 0.095 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain HBS1_N PF08938.5 KFY01143.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 HBS1 N-terminus Zn_clus PF00172.13 KFY01144.1 - 3e-08 33.4 6.4 7.1e-08 32.2 4.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY01144.1 - 0.0089 14.6 0.1 0.014 14.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RGS PF00615.14 KFY01154.1 - 9.2e-12 45.1 0.0 1e-08 35.2 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.14 KFY01155.1 - 1.6e-36 123.8 0.3 2.9e-36 123.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 KFY01156.1 - 3.3e-47 159.4 0.0 3.8e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFY01156.1 - 0.0001 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFY01156.1 - 0.00046 20.0 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFY01156.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 KFY01157.1 - 3.6e-59 200.0 0.0 5.3e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01157.1 - 2.9e-24 85.5 0.0 4.3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.2 KFY01157.1 - 2e-08 33.8 0.1 5.1e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like Kinase-like PF14531.1 KFY01157.1 - 2.1e-06 26.9 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like F-box PF00646.28 KFY01157.1 - 0.00025 20.5 1.0 0.00059 19.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain Kdo PF06293.9 KFY01157.1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFY01157.1 - 0.079 12.6 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family SprT-like PF10263.4 KFY01158.1 - 5.5e-13 48.8 0.0 1.2e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 SprT-like family RRM_1 PF00076.17 KFY01159.1 - 1.2e-14 53.6 0.1 1.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY01159.1 - 1.8e-11 43.8 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY01159.1 - 3.5e-07 29.9 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Saccharop_dh PF03435.13 KFY01160.1 - 1.3e-18 67.2 0.0 1.7e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFY01160.1 - 0.0039 17.2 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KFY01160.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peroxin-13_N PF04088.8 KFY01165.1 - 6.9e-47 159.3 0.3 1.1e-46 158.7 0.2 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Microvir_H PF04687.7 KFY01165.1 - 0.15 11.0 0.5 0.21 10.5 0.3 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) GST_N_3 PF13417.1 KFY01166.1 - 3.7e-09 36.6 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFY01166.1 - 1.6e-08 34.4 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFY01166.1 - 2.9e-08 33.5 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFY01166.1 - 3.8e-08 33.3 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KFY01166.1 - 0.00016 21.5 0.2 0.0024 17.7 0.0 2.6 3 0 0 3 3 3 1 Glutaredoxin GST_C_2 PF13410.1 KFY01166.1 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain COesterase PF00135.23 KFY01167.1 - 4.7e-90 302.8 0.0 6.2e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY01167.1 - 0.0037 16.8 0.0 0.0079 15.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_3 PF13302.1 KFY01168.1 - 2.4e-34 118.5 0.0 2.8e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFY01168.1 - 4.3e-06 26.6 0.5 1.7e-05 24.7 0.4 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY01168.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFY01168.1 - 0.0011 18.6 0.0 0.0037 16.9 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KFY01168.1 - 0.0078 16.1 0.0 0.017 15.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HMG-CoA_red PF00368.13 KFY01169.1 - 8e-156 518.3 4.0 1e-155 517.9 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KFY01169.1 - 4.8e-46 156.2 0.0 1.1e-45 155.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KFY01169.1 - 2.2e-13 49.9 5.3 4.2e-07 29.5 0.1 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFY01169.1 - 1.8e-07 29.5 1.2 3.2e-07 28.7 0.9 1.3 1 0 0 1 1 1 1 Patched family RNR_inhib PF08591.5 KFY01172.1 - 8.3e-24 84.3 1.3 4e-23 82.1 0.9 1.9 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Kelch_3 PF13415.1 KFY01173.1 - 4e-33 112.8 4.6 1.6e-06 28.1 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 KFY01173.1 - 9.8e-22 76.4 17.7 9.9e-13 47.6 0.1 7.8 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KFY01173.1 - 2.1e-14 52.9 2.4 0.0044 17.1 0.1 6.3 5 1 1 6 6 6 2 Kelch motif Kelch_5 PF13854.1 KFY01173.1 - 4.4e-11 42.4 0.2 0.11 12.4 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KFY01173.1 - 4.1e-08 32.6 0.9 0.12 11.9 0.0 7.0 8 2 0 8 8 8 2 Kelch motif Kelch_2 PF07646.10 KFY01173.1 - 8.4e-08 31.6 6.7 1.4 8.8 0.3 6.6 6 2 0 6 6 6 2 Kelch motif PQQ_3 PF13570.1 KFY01173.1 - 0.43 10.9 6.9 7.2 7.0 0.3 4.3 3 1 1 4 4 4 0 PQQ-like domain HSP70 PF00012.15 KFY01174.1 - 8.9e-82 274.9 3.8 1.1e-81 274.6 2.7 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFY01174.1 - 8e-11 41.0 1.3 8.2e-11 41.0 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein Cyt-b5 PF00173.23 KFY01181.1 - 8.7e-13 47.8 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1993 PF09351.5 KFY01182.1 - 9.4e-51 171.9 0.0 1.1e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) FliG_M PF14841.1 KFY01182.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 FliG middle domain RTA1 PF04479.8 KFY01183.1 - 4e-31 108.2 14.7 4.5e-29 101.5 6.4 2.7 1 1 1 2 2 2 1 RTA1 like protein MFS_1 PF07690.11 KFY01185.1 - 6.8e-49 166.4 52.0 6.8e-49 166.4 36.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY01185.1 - 2e-19 69.2 12.7 2e-19 69.2 8.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY01185.1 - 3.4e-17 62.1 6.5 3.4e-17 62.1 4.5 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KFY01185.1 - 1.6e-06 26.8 35.6 0.0015 17.0 8.3 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein ADH_zinc_N PF00107.21 KFY01186.1 - 6.2e-10 38.7 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY01186.1 - 0.0028 18.5 0.0 0.006 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 KFY01187.1 - 4.5e-07 29.6 5.6 7.9e-07 28.8 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.7 KFY01187.1 - 0.021 14.6 1.0 0.03 14.1 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMP-binding PF00501.23 KFY01188.1 - 3e-78 263.0 0.0 5e-78 262.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KFY01188.1 - 1.9e-74 250.3 0.0 3.9e-74 249.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KFY01188.1 - 1.8e-54 184.6 0.4 3.3e-54 183.7 0.3 1.4 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 KFY01188.1 - 8.8e-53 178.6 0.0 9.1e-51 172.0 0.0 3.7 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.16 KFY01188.1 - 4.8e-52 177.2 0.3 1.1e-51 176.1 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KFY01188.1 - 7.4e-45 152.8 0.2 9.4e-42 142.7 0.0 4.0 4 0 0 4 4 4 1 short chain dehydrogenase PS-DH PF14765.1 KFY01188.1 - 3.9e-43 147.7 0.0 7e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFY01188.1 - 4.4e-32 110.4 0.2 2.7e-31 107.8 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFY01188.1 - 2e-31 108.8 0.1 2.4e-29 102.0 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 KFY01188.1 - 2.9e-20 72.2 0.8 2.7e-11 43.5 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KFY01188.1 - 1.1e-18 67.5 0.0 4.9e-18 65.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KFY01188.1 - 2.6e-16 59.7 0.0 3e-11 43.2 0.0 2.9 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 KFY01188.1 - 5.2e-13 49.0 0.0 1.3e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01188.1 - 1.9e-12 47.4 0.0 7.6e-12 45.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01188.1 - 5.6e-09 35.7 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01188.1 - 6.1e-09 36.4 0.0 5.3e-07 30.1 0.0 3.4 3 0 0 3 3 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 KFY01188.1 - 1.4e-08 33.8 0.0 9.7e-05 21.2 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KFY01188.1 - 1.9e-07 30.4 0.0 8.4e-07 28.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family HxxPF_rpt PF13745.1 KFY01188.1 - 2.8e-07 30.7 0.1 1.4e-06 28.4 0.1 2.3 2 0 0 2 2 1 1 HxxPF-repeated domain Thiolase_N PF00108.18 KFY01188.1 - 1.6e-05 24.0 0.0 3.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KFY01188.1 - 0.026 13.9 0.0 0.098 12.1 0.0 2.0 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 KFY01188.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase CDP-OH_P_transf PF01066.16 KFY01191.1 - 7.6e-16 58.2 4.1 7.6e-16 58.2 2.8 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.15 KFY01192.1 - 4.3e-108 361.9 0.3 5.6e-108 361.5 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFY01192.1 - 5.3e-59 198.3 0.8 1e-58 197.4 0.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFY01192.1 - 3.6e-15 56.0 1.3 2.8e-05 24.2 0.1 6.1 3 2 4 7 7 7 3 HEAT repeats HEAT_PBS PF03130.11 KFY01192.1 - 0.0019 18.4 0.2 3.7 8.2 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat MRP-S35 PF10246.4 KFY01192.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 HEAT PF02985.17 KFY01192.1 - 0.04 14.0 9.4 1.4 9.1 0.2 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KFY01192.1 - 0.12 12.8 1.1 0.86 10.1 0.7 2.6 1 0 0 1 1 1 0 HEAT-like repeat Pkinase PF00069.20 KFY01193.1 - 2e-38 132.0 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01193.1 - 1.1e-13 50.8 0.0 1.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY01193.1 - 2.3e-05 24.2 0.0 0.002 17.8 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFY01193.1 - 0.064 12.0 0.1 0.096 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APS_kinase PF01583.15 KFY01194.1 - 4.5e-56 188.8 0.1 6.2e-56 188.4 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 KFY01194.1 - 5.2e-25 88.0 0.0 7.2e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase CPT PF07931.7 KFY01194.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 KFY01194.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ADH_zinc_N PF00107.21 KFY01195.1 - 1.9e-29 101.8 0.1 3.2e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY01195.1 - 2.2e-16 60.8 0.4 4.9e-16 59.7 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY01195.1 - 1.6e-05 24.6 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFY01195.1 - 0.0058 16.2 0.1 0.0086 15.6 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KFY01195.1 - 0.03 13.4 0.1 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_2 PF00152.15 KFY01196.1 - 1.9e-61 207.7 0.0 2.8e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFY01196.1 - 0.0012 18.6 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Borrelia_P83 PF05262.6 KFY01196.1 - 0.26 9.5 6.2 0.39 8.9 4.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 KFY01196.1 - 3.9 6.1 8.8 6 5.5 6.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Methyltransf_16 PF10294.4 KFY01201.1 - 6.6e-17 61.5 0.0 9e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFY01201.1 - 3.3e-05 24.4 0.1 7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY01201.1 - 7.4e-05 22.5 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01201.1 - 0.00013 22.3 0.0 0.00025 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFY01201.1 - 0.00015 21.0 0.0 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFY01201.1 - 0.0092 15.5 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 KFY01201.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.9 KFY01201.1 - 0.013 14.8 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 KFY01201.1 - 0.021 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.7 KFY01201.1 - 0.037 14.4 0.1 0.082 13.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KFY01201.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribonuc_L-PSP PF01042.16 KFY01202.1 - 3.4e-20 72.0 0.0 3.9e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAO PF01266.19 KFY01203.1 - 5.9e-13 48.4 0.1 7.7e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2427 PF10348.4 KFY01204.1 - 8.4e-06 25.3 4.5 0.011 15.3 0.5 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KFY01204.1 - 3.9e-05 23.5 8.7 7.9e-05 22.4 6.1 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CENP_C_N PF15622.1 KFY01204.1 - 0.052 12.7 0.1 0.069 12.3 0.1 1.1 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal DUF2306 PF10067.4 KFY01204.1 - 1 9.5 9.6 0.056 13.5 0.8 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF2231 PF09990.4 KFY01204.1 - 1.2 9.5 5.3 4.3 7.7 2.0 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Mito_carr PF00153.22 KFY01205.1 - 1.9e-25 88.3 7.4 2.2e-11 43.3 0.1 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein Copper-bind PF00127.15 KFY01205.1 - 0.01 16.0 0.1 0.066 13.4 0.1 2.2 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family E1-E2_ATPase PF00122.15 KFY01207.1 - 9.5e-63 211.3 6.5 2.6e-62 209.8 4.5 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY01207.1 - 2.2e-23 83.8 0.0 4.1e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY01207.1 - 3.9e-13 49.9 0.0 1.1e-12 48.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFY01207.1 - 2e-12 46.3 0.0 4.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFY01207.1 - 0.0014 18.2 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY01207.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Prothymosin PF03247.9 KFY01207.1 - 0.39 10.8 12.5 0.71 10.0 8.6 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nop14 PF04147.7 KFY01207.1 - 0.53 8.1 7.6 0.75 7.6 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KFY01207.1 - 9.4 4.5 10.0 13 4.1 6.9 1.1 1 0 0 1 1 1 0 Daxx Family Dicty_CAR PF05462.6 KFY01217.1 - 8e-07 28.2 3.6 8e-07 28.2 2.5 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KFY01217.1 - 0.013 15.0 5.4 0.022 14.3 3.0 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF4064 PF13273.1 KFY01217.1 - 0.15 12.1 2.8 11 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) ATP-synt_C PF00137.16 KFY01218.1 - 2.8e-51 171.2 65.4 3.6e-16 58.8 10.3 4.1 4 0 0 4 4 4 4 ATP synthase subunit C GerA PF03323.8 KFY01218.1 - 1 7.4 4.9 2.4 6.2 0.5 2.6 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein TspO_MBR PF03073.10 KFY01218.1 - 1.1 8.8 5.6 1.5 8.3 0.0 3.0 3 0 0 3 3 3 0 TspO/MBR family Fungal_trans_2 PF11951.3 KFY01219.1 - 2.7e-07 29.5 0.3 5.1e-07 28.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BRO1 PF03097.13 KFY01219.1 - 0.07 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain Glyoxalase_2 PF12681.2 KFY01220.1 - 1.3e-07 32.1 0.1 1.9e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFY01220.1 - 0.0013 18.6 0.1 0.0043 17.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Zn_clus PF00172.13 KFY01221.1 - 3.5e-05 23.6 12.9 5.4e-05 23.0 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFY01222.1 - 5.4e-23 81.2 25.1 5.4e-23 81.2 17.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 KFY01222.1 - 3.5 6.9 12.1 0.34 10.3 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PI3_PI4_kinase PF00454.22 KFY01226.1 - 6.1e-32 110.9 0.0 1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KFY01226.1 - 1.1e-18 66.7 0.0 2.4e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.1 KFY01226.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.15 KFY01226.1 - 0.27 10.3 0.4 0.52 9.4 0.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 KFY01227.1 - 1.1e-19 70.6 0.0 3.8e-19 68.8 0.0 1.7 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01227.1 - 1.3e-19 70.3 0.0 6.3e-18 64.7 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.2 KFY01227.1 - 2.3e-17 62.1 4.5 1.7e-05 24.2 0.0 5.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFY01227.1 - 3.1e-16 58.8 2.0 1.7e-09 37.3 0.2 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFY01227.1 - 2.2e-10 39.0 6.0 0.0017 18.1 0.3 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat Kdo PF06293.9 KFY01227.1 - 1.2e-06 27.7 0.0 2.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_7 PF13504.1 KFY01227.1 - 3.1e-05 23.4 7.9 1.6 9.2 0.1 5.9 5 0 0 5 5 5 1 Leucine rich repeat Kinase-like PF14531.1 KFY01227.1 - 0.00049 19.1 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFY01227.1 - 0.0019 17.9 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFY01227.1 - 0.023 14.0 0.1 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 RIO1 family LRR_6 PF13516.1 KFY01227.1 - 0.18 11.9 4.6 33 4.9 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat DUF1759 PF03564.10 KFY01231.1 - 0.47 10.2 4.8 0.35 10.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) CysG_dimeriser PF10414.4 KFY01231.1 - 0.58 9.6 3.2 15 5.1 0.1 2.8 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region TPR_11 PF13414.1 KFY01232.1 - 2.2e-36 123.3 25.1 2.3e-10 39.9 2.5 7.3 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFY01232.1 - 9.2e-31 104.1 22.3 4.1e-07 29.3 0.1 8.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFY01232.1 - 2.2e-29 98.9 31.1 1.9e-05 24.2 0.1 9.6 11 0 0 11 11 10 8 Tetratricopeptide repeat Apc3 PF12895.2 KFY01232.1 - 4.7e-27 93.9 19.7 4.3e-20 71.6 0.5 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFY01232.1 - 5.2e-23 80.7 23.1 1.6e-06 27.9 0.5 7.7 6 2 1 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFY01232.1 - 1.5e-21 74.4 9.0 0.00019 20.9 0.2 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFY01232.1 - 4.3e-18 65.3 10.4 0.00034 20.8 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFY01232.1 - 8.8e-18 64.4 26.0 4.6e-07 30.3 1.0 7.8 5 3 2 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFY01232.1 - 2.5e-15 55.2 12.8 0.74 10.1 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFY01232.1 - 2.1e-14 52.7 14.5 0.27 11.9 0.1 9.8 6 3 5 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFY01232.1 - 6e-14 50.6 9.8 0.0077 15.9 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFY01232.1 - 4.1e-09 36.3 14.4 2.1 9.0 0.5 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFY01232.1 - 0.003 17.6 4.0 12 6.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFY01232.1 - 0.0086 15.9 9.8 20 5.1 0.1 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF788 PF05620.6 KFY01233.1 - 1.5e-43 148.6 0.0 1.6e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Histone PF00125.19 KFY01234.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFY01234.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KFY01234.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFY01234.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFY01234.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFY01234.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CTK3 PF12243.3 KFY01235.1 - 3.5e-54 182.2 0.4 4.7e-54 181.7 0.2 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KFY01235.1 - 2e-19 69.3 4.7 4.7e-19 68.1 3.3 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KFY01235.1 - 0.042 13.6 0.3 0.073 12.8 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial glycoprotein Gasdermin PF04598.7 KFY01235.1 - 0.094 11.4 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Gasdermin family P5CR_dimer PF14748.1 KFY01236.1 - 1.5e-33 114.9 0.5 3.9e-33 113.6 0.3 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFY01236.1 - 5e-10 39.6 0.2 8.5e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CAP160 PF07918.6 KFY01236.1 - 0.016 14.8 0.4 0.038 13.6 0.3 1.6 1 0 0 1 1 1 0 CAP160 repeat Hat1_N PF10394.4 KFY01237.1 - 1.9e-41 141.8 0.0 4.7e-41 140.5 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Glyco_hydro_16 PF00722.16 KFY01260.1 - 4.7e-41 140.1 1.8 7.5e-41 139.4 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PP2C PF00481.16 KFY01261.1 - 1.3e-52 178.7 0.0 2.3e-52 177.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KFY01261.1 - 3.5e-39 131.7 45.5 3.5e-07 29.6 0.5 12.6 7 3 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFY01261.1 - 4.2e-39 132.0 43.0 1.8e-10 40.4 0.7 9.5 5 4 4 10 10 10 8 Leucine rich repeat Guanylate_cyc PF00211.15 KFY01261.1 - 4.3e-28 97.9 0.0 1e-27 96.7 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KFY01261.1 - 2.9e-22 75.2 47.8 0.13 12.3 0.0 18.9 20 0 0 20 20 20 8 Leucine Rich Repeat RA PF00788.18 KFY01261.1 - 9e-13 48.5 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 KFY01261.1 - 1.4e-12 45.6 49.4 0.48 10.8 0.1 15.9 18 0 0 18 18 16 4 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 KFY01261.1 - 2.5e-06 26.7 0.0 1.1e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.1 KFY01261.1 - 0.0028 17.2 9.4 0.061 12.8 0.1 4.2 2 1 1 4 4 4 1 Leucine-rich repeat LRR_5 PF13306.1 KFY01261.1 - 0.0059 16.2 0.0 2.7 7.7 0.0 3.3 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 KFY01261.1 - 1.2 9.3 47.6 4.8 7.5 0.2 14.1 18 1 1 19 19 17 0 Leucine Rich repeat Sugar_tr PF00083.19 KFY01274.1 - 3.9e-16 58.6 6.0 4.2e-16 58.5 4.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Claudin_3 PF06653.6 KFY01274.1 - 0.4 10.3 2.4 0.57 9.8 1.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF3328 PF11807.3 KFY01281.1 - 0.035 13.7 1.2 0.71 9.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) MFS_1 PF07690.11 KFY01282.1 - 1.6e-42 145.4 47.3 4.5e-42 144.0 30.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY01282.1 - 1.1e-15 57.1 7.3 1.1e-15 57.1 5.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KFY01282.1 - 4.5e-08 31.9 5.3 4.5e-08 31.9 3.7 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 KFY01282.1 - 9.6e-06 24.0 16.4 9.6e-06 24.0 11.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 KFY01283.1 - 1.4e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFY01283.1 - 0.0012 18.3 1.4 0.093 12.1 0.9 2.8 1 1 0 1 1 1 1 Peptidase C26 Senescence PF06911.7 KFY01284.1 - 1e-44 152.4 6.9 1.5e-44 151.7 4.8 1.3 1 0 0 1 1 1 1 Senescence-associated protein Rho_GDI PF02115.12 KFY01285.1 - 5.7e-59 198.8 0.3 6.3e-59 198.7 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 KFY01286.1 - 2.6e-43 147.7 0.6 3.2e-43 147.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 KFY01287.1 - 0.0004 20.1 1.7 0.00074 19.3 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Adaptin_N PF01602.15 KFY01288.1 - 6.4e-106 354.7 0.0 7.8e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KFY01288.1 - 2e-13 50.3 1.1 4.9e-05 23.5 0.0 5.1 3 2 2 5 5 5 5 HEAT repeats HEAT PF02985.17 KFY01288.1 - 2.2e-10 39.7 0.0 0.058 13.5 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFY01288.1 - 4.4e-05 23.8 2.2 0.0093 16.4 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KFY01288.1 - 0.0036 17.2 0.1 1.2 9.2 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion VHS PF00790.14 KFY01288.1 - 0.025 14.2 0.5 52 3.4 0.0 4.0 4 0 0 4 4 4 0 VHS domain Cnd1 PF12717.2 KFY01288.1 - 0.13 12.1 0.0 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TFIIA PF03153.8 KFY01288.1 - 6.6 6.5 19.6 12 5.6 13.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 KFY01288.1 - 8.4 5.2 6.9 15 4.4 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UCR_TM PF02921.9 KFY01290.1 - 1.6e-20 73.1 1.7 1.6e-20 73.1 1.2 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KFY01290.1 - 1e-18 66.6 0.0 1.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pectinesterase PF01095.14 KFY01291.1 - 1e-31 109.6 0.3 3.7e-24 84.8 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase Alpha-amylase PF00128.19 KFY01292.1 - 1.7e-96 323.3 0.9 2.5e-96 322.8 0.2 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFY01292.1 - 0.02 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 KFY01292.1 - 0.037 13.5 0.2 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.19 KFY01293.1 - 3.5e-86 289.5 25.3 4.1e-86 289.3 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01293.1 - 5.9e-17 61.4 27.2 5.9e-17 61.4 18.8 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY01293.1 - 0.00027 19.4 32.2 0.0013 17.1 4.6 3.5 2 2 2 4 4 4 3 MFS/sugar transport protein Fungal_trans PF04082.13 KFY01294.1 - 8.3e-15 54.3 2.4 1.3e-14 53.6 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01294.1 - 2.2e-06 27.4 11.7 5.1e-06 26.2 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_28 PF00295.12 KFY01295.1 - 5.9e-44 150.3 8.0 9.1e-44 149.7 5.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 KFY01296.1 - 2e-39 135.4 15.4 2.5e-39 135.1 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.3 KFY01296.1 - 0.00027 20.3 0.4 0.00068 19.0 0.0 1.9 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Pectinesterase PF01095.14 KFY01297.1 - 2.6e-49 167.4 9.3 3.2e-49 167.0 6.4 1.0 1 0 0 1 1 1 1 Pectinesterase Sugar_tr PF00083.19 KFY01298.1 - 7.2e-88 295.1 22.8 2.3e-82 276.9 10.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY01298.1 - 1.8e-28 99.2 32.7 1e-27 96.7 17.0 3.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY01298.1 - 0.00092 17.7 28.5 0.0015 17.0 3.7 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein PUCC PF03209.10 KFY01298.1 - 0.062 12.0 10.0 0.016 13.9 4.1 2.0 2 0 0 2 2 2 0 PUCC protein Cpn60_TCP1 PF00118.19 KFY01299.1 - 6e-143 476.9 15.9 6.9e-143 476.7 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 KFY01300.1 - 6.2e-21 74.7 0.1 6e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFY01300.1 - 7.1e-19 67.5 0.0 1.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 KFY01300.1 - 4.7e-14 52.0 1.7 1.3e-13 50.6 1.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF2048 PF09752.4 KFY01302.1 - 0.047 12.5 0.2 0.077 11.8 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Cep57_MT_bd PF06657.8 KFY01302.1 - 1 9.3 3.6 0.83 9.6 0.1 2.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ALG3 PF05208.8 KFY01303.1 - 6e-142 473.2 15.1 6.9e-142 473.0 10.4 1.0 1 0 0 1 1 1 1 ALG3 protein Adeno_E3_CR2 PF02439.10 KFY01303.1 - 0.054 13.0 2.4 0.14 11.7 0.2 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 eIF-1a PF01176.14 KFY01304.1 - 9.1e-16 57.0 0.0 2.1e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 BCIP PF13862.1 KFY01306.1 - 3.2e-69 232.3 0.4 3.9e-69 232.0 0.3 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 KFY01307.1 - 1.1e-09 38.2 0.1 1.6e-06 28.1 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II TauD PF02668.11 KFY01322.1 - 4.7e-59 200.1 0.2 6.3e-59 199.7 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KFY01322.1 - 0.021 15.2 0.2 0.054 14.0 0.2 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 KFY01322.1 - 0.025 13.4 0.0 0.098 11.5 0.0 1.9 2 0 0 2 2 2 0 CsiD Mito_carr PF00153.22 KFY01323.1 - 5.7e-66 218.2 4.3 2.1e-22 78.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIID_30kDa PF03540.8 KFY01324.1 - 2.2e-26 91.4 0.2 3.1e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KFY01324.1 - 0.28 11.6 0.3 0.28 11.6 0.2 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF962 PF06127.6 KFY01326.1 - 2.7e-24 84.8 0.0 4.2e-24 84.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3270 PF11674.3 KFY01326.1 - 0.3 11.1 1.4 0.8 9.7 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) SHS2_Rpb7-N PF03876.12 KFY01327.1 - 3.8e-16 58.9 0.0 6.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KFY01327.1 - 2.1e-08 34.1 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KFY01327.1 - 0.0011 19.2 0.1 0.0022 18.1 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 XPG_I PF00867.13 KFY01328.1 - 1.8e-22 79.1 0.0 3.1e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFY01328.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 KFY01329.1 - 5.5e-23 81.0 0.0 1.9e-21 75.9 0.0 2.6 2 1 0 2 2 2 2 Actin ATP-synt_ab PF00006.20 KFY01330.1 - 1e-70 237.6 0.0 1.6e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFY01330.1 - 2.8e-27 95.4 0.2 8e-27 93.9 0.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFY01330.1 - 1.1e-15 57.5 2.7 2.7e-15 56.3 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KFY01330.1 - 0.011 15.6 1.1 0.028 14.3 0.6 1.9 2 0 0 2 2 2 0 HAS barrel domain Arch_ATPase PF01637.13 KFY01330.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KFY01330.1 - 0.029 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain GAF PF01590.21 KFY01331.1 - 4e-06 27.0 0.0 1.3e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain Prok-E2_B PF14461.1 KFY01331.1 - 0.12 12.0 1.7 28 4.4 0.0 3.2 2 1 1 3 3 3 0 Prokaryotic E2 family B Ribosomal_L27e PF01777.13 KFY01332.1 - 1.4e-37 127.6 3.0 1.8e-37 127.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KFY01332.1 - 0.0014 18.2 1.5 0.0021 17.6 0.1 2.0 2 0 0 2 2 2 1 KOW motif ECM11 PF15463.1 KFY01332.1 - 0.18 12.1 1.7 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Extracellular mutant protein 11 Tup_N PF08581.5 KFY01333.1 - 0.24 11.6 23.5 1 9.5 0.1 6.9 5 1 1 6 6 6 0 Tup N-terminal Iron_permease PF04120.7 KFY01333.1 - 9.6 5.7 16.3 0.035 13.6 0.7 4.1 4 0 0 4 4 4 0 Low affinity iron permease Abhydrolase_6 PF12697.2 KFY01334.1 - 2.5e-29 102.7 0.1 3.4e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01334.1 - 1.7e-11 44.0 0.0 3.8e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY01334.1 - 1.1e-07 31.6 0.1 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFY01334.1 - 8.9e-05 22.2 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Allantoicase PF03561.10 KFY01335.1 - 6.9e-91 301.5 0.4 1.8e-45 154.1 0.1 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 KFY01335.1 - 0.0024 17.7 0.1 0.009 15.8 0.0 1.9 2 0 0 2 2 2 1 F5/8 type C domain Arginosuc_synth PF00764.14 KFY01337.1 - 4.8e-150 499.9 0.0 5.6e-150 499.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 KFY01337.1 - 0.0044 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KFY01337.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC F-box-like PF12937.2 KFY01338.1 - 0.0001 21.9 0.6 0.00017 21.2 0.1 1.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFY01338.1 - 0.00023 20.7 0.1 0.00023 20.7 0.0 2.3 3 0 0 3 3 3 1 F-box domain DUF4524 PF15025.1 KFY01338.1 - 0.0024 17.3 0.0 0.016 14.6 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4524) DZR PF12773.2 KFY01338.1 - 0.2 11.5 6.0 0.29 10.9 1.0 2.7 1 1 1 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 KFY01338.1 - 3 7.7 12.5 8.1 6.3 2.3 3.4 2 1 1 3 3 3 0 Transposase zinc-ribbon domain F-box PF00646.28 KFY01339.1 - 2.1e-05 24.0 0.0 2.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFY01339.1 - 0.034 13.8 0.1 0.034 13.8 0.1 1.6 2 0 0 2 2 2 0 F-box-like Aldedh PF00171.17 KFY01340.1 - 1.1e-152 508.6 0.9 1.5e-152 508.2 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box PF00646.28 KFY01340.1 - 7.7e-08 31.8 0.9 3.9e-07 29.5 0.0 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KFY01340.1 - 0.0031 17.1 0.2 0.01 15.5 0.1 1.9 2 0 0 2 2 2 1 F-box-like DUF1487 PF07368.6 KFY01340.1 - 0.039 13.1 0.0 0.15 11.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) OmdA PF13376.1 KFY01340.1 - 0.11 12.1 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF2435 PF10363.4 KFY01341.1 - 4.1e-16 58.6 0.0 2.1e-15 56.3 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KFY01341.1 - 5.4e-08 32.1 0.2 1.2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DASH_Dad3 PF08656.5 KFY01342.1 - 3.7e-26 90.6 0.3 4.6e-26 90.3 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.10 KFY01343.1 - 2.9e-17 61.6 0.0 5.9e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KFY01343.1 - 3.6e-11 42.6 0.1 7e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.6 KFY01344.1 - 4.8e-11 41.9 0.0 2.3e-09 36.4 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 KFY01344.1 - 9.5e-07 28.5 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KFY01344.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 KFY01344.1 - 8.9e-05 22.2 0.0 0.00038 20.1 0.0 2.0 2 0 0 2 2 2 1 TRAM domain PrmA PF06325.8 KFY01344.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFY01344.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFY01344.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 KFY01344.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UNC45-central PF11701.3 KFY01345.1 - 5.2e-41 139.8 0.0 9.9e-39 132.5 0.0 3.5 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KFY01345.1 - 1.3e-07 31.8 11.5 0.02 15.1 1.7 5.8 4 2 2 6 6 6 4 HEAT repeats Arm PF00514.18 KFY01345.1 - 0.00044 19.9 22.4 0.18 11.7 0.0 8.3 8 1 0 8 8 8 3 Armadillo/beta-catenin-like repeat Tfb4 PF03850.9 KFY01346.1 - 3.1e-106 354.6 0.0 3.5e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KFY01346.1 - 0.0074 16.4 0.2 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain ADH_N PF08240.7 KFY01347.1 - 6.7e-29 99.8 0.9 1.1e-28 99.1 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY01347.1 - 3e-25 88.2 0.9 3.9e-25 87.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFY01347.1 - 0.0095 15.1 0.2 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glucokinase PF02685.11 KFY01347.1 - 0.08 11.7 0.5 0.15 10.8 0.3 1.4 1 0 0 1 1 1 0 Glucokinase DUF16 PF01519.11 KFY01348.1 - 0.14 12.3 0.5 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Actin PF00022.14 KFY01349.1 - 3.4e-89 298.9 0.0 7.4e-89 297.8 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFY01349.1 - 0.018 13.6 0.0 2.9 6.3 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 KFY01350.1 - 8e-35 120.0 0.3 3.2e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Mtc PF03820.12 KFY01364.1 - 4.2e-55 186.5 1.2 1.3e-54 184.9 0.8 1.6 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 KFY01365.1 - 2.8e-58 197.1 0.0 4.3e-58 196.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01365.1 - 4.3e-21 75.1 0.0 3.4e-20 72.1 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase DUF221 PF02714.10 KFY01387.1 - 4e-25 88.3 2.7 6e-25 87.7 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KFY01387.1 - 2.1e-13 49.9 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Phosphate metabolism protein FtsX PF02687.16 KFY01387.1 - 0.14 11.9 6.8 0.029 14.1 2.0 1.7 2 0 0 2 2 2 0 FtsX-like permease family Mgr1 PF08602.5 KFY01387.1 - 0.46 9.4 1.5 0.53 9.2 1.1 1.3 1 1 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit EcoRI PF02963.11 KFY01388.1 - 0.0057 15.4 0.0 0.012 14.4 0.0 1.5 2 0 0 2 2 2 1 Restriction endonuclease EcoRI bZIP_2 PF07716.10 KFY01389.1 - 0.19 11.5 7.5 0.074 12.8 2.2 2.1 2 0 0 2 2 2 0 Basic region leucine zipper FMN_red PF03358.10 KFY01399.1 - 8.3e-25 87.0 0.0 1.3e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFY01399.1 - 3.8e-07 29.8 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Zn_clus PF00172.13 KFY01400.1 - 4.1e-07 29.8 11.5 1e-06 28.5 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY01400.1 - 7.6e-05 21.7 0.0 0.00017 20.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Avl9 PF09794.4 KFY01401.1 - 4.7e-146 486.1 0.0 6.6e-146 485.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 End3 PF12761.2 KFY01401.1 - 8.5e-75 250.6 0.4 1.5e-74 249.8 0.2 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KFY01401.1 - 2.2e-51 171.9 0.0 2.1e-49 165.5 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2347 PF09804.4 KFY01401.1 - 2.2e-07 30.4 0.1 2.6e-06 26.9 0.1 2.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) EF-hand_1 PF00036.27 KFY01401.1 - 2.4e-07 29.5 1.8 1.5e-06 27.0 0.2 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 KFY01401.1 - 2.6e-07 30.1 1.5 2e-06 27.2 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair SPA PF08616.5 KFY01401.1 - 1.7e-06 27.6 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis EF-hand_7 PF13499.1 KFY01401.1 - 2.9e-05 24.1 0.1 0.00031 20.8 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFY01401.1 - 0.00017 21.2 0.6 0.0036 17.0 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KFY01401.1 - 0.013 14.8 0.1 0.045 13.1 0.1 2.0 1 0 0 1 1 1 0 EF hand Spc24 PF08286.6 KFY01404.1 - 6.1e-35 119.4 4.5 1.4e-33 115.0 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 KFY01404.1 - 0.00013 21.6 3.2 0.18 11.5 0.1 2.3 2 0 0 2 2 2 2 Prefoldin subunit TPR_MLP1_2 PF07926.7 KFY01404.1 - 0.0025 17.5 8.2 0.0037 16.9 5.7 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 KFY01404.1 - 0.023 14.5 3.4 3.9 7.4 0.3 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 KFY01404.1 - 0.024 13.8 3.4 0.028 13.6 2.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF342 PF03961.8 KFY01404.1 - 0.034 12.5 3.1 0.043 12.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Streptin-Immun PF11083.3 KFY01404.1 - 0.049 13.6 2.1 0.079 12.9 0.4 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein APG6 PF04111.7 KFY01404.1 - 0.066 12.2 6.0 0.085 11.8 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 KFY01404.1 - 0.1 11.7 3.8 0.12 11.5 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Troponin PF00992.15 KFY01404.1 - 0.16 12.0 3.0 0.31 11.0 2.0 1.5 1 1 0 1 1 1 0 Troponin Laminin_II PF06009.7 KFY01404.1 - 0.17 11.6 5.6 0.24 11.1 3.5 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF948 PF06103.6 KFY01404.1 - 0.38 10.6 4.7 4.3 7.2 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Lipoprotein_16 PF03923.8 KFY01404.1 - 0.41 9.9 4.7 0.12 11.7 1.1 1.6 2 0 0 2 2 2 0 Uncharacterized lipoprotein Occludin_ELL PF07303.8 KFY01404.1 - 0.42 11.3 3.0 1.1 10.0 1.6 2.0 1 1 1 2 2 2 0 Occludin homology domain Noelin-1 PF12308.3 KFY01404.1 - 0.66 9.7 2.9 0.68 9.7 0.6 2.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein Syntaxin-6_N PF09177.6 KFY01404.1 - 0.77 10.1 8.3 1.4 9.3 1.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TBPIP PF07106.8 KFY01404.1 - 0.83 9.1 8.5 2.6 7.5 0.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 KFY01404.1 - 1.2 9.3 8.1 1.1 9.4 4.3 1.8 1 1 1 2 2 2 0 Syntaxin Viral_P18 PF04521.8 KFY01404.1 - 1.3 8.4 9.8 0.78 9.2 2.2 2.3 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FlxA PF14282.1 KFY01404.1 - 4.2 7.3 10.9 2 8.4 1.8 2.3 1 1 1 2 2 2 0 FlxA-like protein Cep57_MT_bd PF06657.8 KFY01404.1 - 4.8 7.1 9.1 1.3 9.0 1.1 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PCRF PF03462.13 KFY01404.1 - 5.5 6.7 5.8 5.1 6.8 0.6 2.3 1 1 1 2 2 2 0 PCRF domain GvpG PF05120.7 KFY01404.1 - 9.7 6.0 7.8 0.79 9.5 1.7 1.9 2 1 0 2 2 2 0 Gas vesicle protein G Fis1_TPR_C PF14853.1 KFY01405.1 - 2e-23 82.0 0.5 4.3e-23 80.9 0.4 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat zf-RING_2 PF13639.1 KFY01405.1 - 2.2e-15 56.2 13.7 3.1e-15 55.6 4.8 2.3 2 0 0 2 2 2 1 Ring finger domain Fis1_TPR_N PF14852.1 KFY01405.1 - 2.7e-15 55.3 0.0 5.4e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-C3HC4_3 PF13920.1 KFY01405.1 - 3.9e-11 42.4 8.5 9.1e-10 38.0 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY01405.1 - 4e-08 33.1 12.6 6.7e-08 32.4 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFY01405.1 - 1e-07 31.9 7.3 3.7e-07 30.1 2.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFY01405.1 - 3.8e-07 29.7 3.6 3.8e-07 29.7 2.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFY01405.1 - 4.9e-06 26.1 14.4 2e-05 24.1 3.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 KFY01405.1 - 0.00024 20.7 0.2 0.00024 20.7 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KFY01405.1 - 0.0015 18.5 3.3 0.0015 18.5 2.3 2.5 2 0 0 2 2 2 1 zinc-finger DUF1272 PF06906.6 KFY01405.1 - 0.0028 17.4 5.4 0.22 11.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 KFY01405.1 - 0.0049 16.6 1.6 0.0049 16.6 1.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 KFY01405.1 - 0.012 15.4 0.6 0.029 14.2 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Prok-RING_4 PF14447.1 KFY01405.1 - 0.047 13.2 2.7 0.12 11.9 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 KFY01405.1 - 0.61 9.8 12.8 3.2 7.5 0.5 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Baculo_RING PF05883.6 KFY01405.1 - 0.93 9.3 4.7 0.23 11.2 0.6 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 KFY01405.1 - 2 8.3 12.9 4.6 7.1 0.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KFY01405.1 - 5.4 7.1 14.3 0.75 9.8 5.1 2.4 2 0 0 2 2 2 0 RING-variant domain zinc-ribbons_6 PF07191.7 KFY01405.1 - 6 6.7 6.0 4.5 7.1 0.1 2.8 2 1 0 3 3 3 0 zinc-ribbons PHD PF00628.24 KFY01405.1 - 9.9 5.9 16.7 0.47 10.1 4.1 2.6 2 1 0 2 2 2 0 PHD-finger Fungal_trans PF04082.13 KFY01406.1 - 2.5e-24 85.5 4.1 2.6e-24 85.5 2.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01406.1 - 2.8e-08 33.5 8.8 5.1e-08 32.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KFY01407.1 - 6.3e-11 42.5 0.0 1.6e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFY01407.1 - 8.8e-05 21.6 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFY01407.1 - 0.00026 20.7 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFY01407.1 - 0.00033 20.3 0.0 0.00094 18.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFY01407.1 - 0.00038 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFY01407.1 - 0.0018 17.0 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFY01407.1 - 0.0028 17.5 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFY01407.1 - 0.0065 17.2 0.3 0.19 12.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFY01407.1 - 0.026 13.6 0.0 0.069 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KFY01407.1 - 0.027 14.3 0.2 0.069 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 KFY01407.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 KFY01407.1 - 0.075 13.0 0.1 0.28 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 KFY01407.1 - 0.077 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 NTPase Phosphorylase PF00343.15 KFY01409.1 - 0 1063.8 0.2 0 1063.5 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.15 KFY01410.1 - 5.1e-120 400.7 0.0 6.1e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFY01410.1 - 8.2e-15 54.4 0.6 6.6e-10 38.5 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFY01410.1 - 0.00043 19.4 0.2 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KFY01410.1 - 0.005 17.3 0.0 0.99 9.9 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein AAA_29 PF13555.1 KFY01410.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.2 KFY01411.1 - 1.5e-25 90.4 1.2 1.6e-25 90.3 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY01411.1 - 1.8e-15 57.1 0.0 1e-11 44.8 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY01411.1 - 2.4e-12 46.8 0.0 1.5e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KFY01411.1 - 1.4e-05 24.3 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 KFY01411.1 - 1.4e-05 24.6 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 KFY01411.1 - 0.00081 18.3 0.0 0.0018 17.2 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KFY01411.1 - 0.0078 15.8 0.0 0.13 11.8 0.0 2.6 3 1 0 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KFY01411.1 - 0.023 14.2 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 KFY01411.1 - 0.026 14.7 0.3 0.087 13.0 0.2 1.9 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.6 KFY01411.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2305 PF10230.4 KFY01411.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 KFY01411.1 - 0.14 11.6 0.0 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KFY01411.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Spo7 PF03907.8 KFY01412.1 - 3.5e-71 239.1 0.0 4.9e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein GST_N PF02798.15 KFY01413.1 - 3.9e-11 42.9 0.2 1.8e-10 40.8 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFY01413.1 - 6.2e-11 42.1 0.2 9.6e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFY01413.1 - 6.7e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFY01413.1 - 5.7e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFY01413.1 - 6.7e-08 32.4 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFY01413.1 - 3.3e-06 27.5 0.1 4.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NOPS PF08075.6 KFY01413.1 - 0.02 15.2 0.1 0.047 14.1 0.1 1.7 1 0 0 1 1 1 0 NOPS (NUC059) domain HET PF06985.6 KFY01424.1 - 2.7e-28 98.8 0.7 5e-28 98.0 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_33 PF13671.1 KFY01426.1 - 0.0099 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KFY01426.1 - 0.012 15.5 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.1 KFY01426.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain HPS3_N PF14761.1 KFY01426.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Zn_clus PF00172.13 KFY01428.1 - 1.8e-05 24.5 11.5 4.2e-05 23.3 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY01428.1 - 6.7e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSPI PF14098.1 KFY01430.1 - 0.047 13.6 0.1 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore protein I APH PF01636.18 KFY01432.1 - 0.0012 18.6 0.0 0.0054 16.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family muHD PF10291.4 KFY01442.1 - 1e-57 195.2 0.0 2.2e-57 194.2 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KFY01442.1 - 1.3e-09 38.0 0.0 4.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Fib_alpha PF08702.5 KFY01442.1 - 0.031 14.4 2.9 0.074 13.1 2.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Muted PF14942.1 KFY01442.1 - 0.053 13.3 2.5 0.12 12.2 1.7 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Fis1_TPR_C PF14853.1 KFY01442.1 - 0.068 13.0 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.20 KFY01443.1 - 1.4e-38 132.5 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01443.1 - 4.4e-18 65.2 0.0 6.9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY01443.1 - 0.00046 19.9 0.1 0.0033 17.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Orbi_NS3 PF01616.11 KFY01443.1 - 0.35 9.8 1.6 0.91 8.4 1.1 1.6 1 0 0 1 1 1 0 Orbivirus NS3 Mmp37 PF09139.6 KFY01444.1 - 2.8e-132 440.7 0.0 3.8e-132 440.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 PYC_OADA PF02436.13 KFY01444.1 - 0.028 13.8 0.2 0.058 12.8 0.2 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain DAO PF01266.19 KFY01445.1 - 8.6e-51 172.9 1.7 9.8e-51 172.7 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY01445.1 - 2e-05 24.5 1.7 4.3e-05 23.4 1.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFY01445.1 - 5.4e-05 22.4 0.7 0.27 10.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KFY01445.1 - 9.1e-05 22.6 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFY01445.1 - 0.00039 19.6 0.2 0.0011 18.2 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFY01445.1 - 0.00086 19.2 1.4 0.0044 16.9 0.7 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY01445.1 - 0.037 14.4 0.5 0.46 10.9 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFY01445.1 - 0.089 12.8 0.2 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.19 KFY01445.1 - 0.11 11.3 1.2 0.44 9.3 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KFY01445.1 - 0.15 11.8 0.6 0.33 10.7 0.3 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2046 PF09755.4 KFY01446.1 - 0.033 13.0 0.8 0.033 13.0 0.6 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) CYSTM PF12734.2 KFY01447.1 - 6e-12 45.4 16.0 6e-12 45.4 11.1 5.3 2 1 3 5 5 5 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.8 KFY01447.1 - 6.1 6.8 8.1 16 5.5 5.6 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M43 PF05572.8 KFY01448.1 - 2.4e-17 62.9 0.4 4.3e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KFY01448.1 - 2e-05 24.5 4.7 4e-05 23.6 3.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFY01448.1 - 8.2e-05 23.1 1.5 0.0002 21.8 1.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFY01448.1 - 0.0002 21.4 3.2 0.00034 20.7 2.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFY01448.1 - 0.0011 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFY01448.1 - 0.0017 17.2 0.2 0.0023 16.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M57 PF12388.3 KFY01448.1 - 0.0063 15.8 0.7 0.0063 15.8 0.5 1.7 1 1 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 KFY01448.1 - 0.0099 15.4 1.6 0.015 14.8 1.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFY01448.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 tRNA-synt_2c PF01411.14 KFY01449.1 - 1e-07 30.6 0.0 1.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFY01449.1 - 7.6e-05 22.5 0.5 0.00016 21.4 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HET PF06985.6 KFY01450.1 - 1.2e-22 80.6 2.6 1.5e-21 76.9 1.1 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 KFY01451.1 - 1.9e-51 174.5 0.0 2.2e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 KFY01468.1 - 3.8e-25 88.6 1.2 1.4e-24 86.8 0.9 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 KFY01469.1 - 1.4e-07 30.6 0.0 8.9e-07 28.0 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KFY01470.1 - 5.4e-05 23.2 8.4 0.07 13.4 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY01470.1 - 0.0075 16.5 12.1 0.033 14.5 0.5 2.7 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFY01470.1 - 0.027 14.7 0.8 0.027 14.7 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double domain HhH-GPD PF00730.20 KFY01472.1 - 9.8e-16 57.9 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFY01472.1 - 1.7e-08 33.6 0.2 6.9e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_8 PF14716.1 KFY01472.1 - 0.044 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain 2TM PF13239.1 KFY01474.1 - 0.022 14.8 3.0 0.059 13.4 0.3 2.4 2 0 0 2 2 2 0 2TM domain DUF1352 PF07086.7 KFY01474.1 - 0.38 10.3 3.4 1.1 8.8 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1352) ADH_N PF08240.7 KFY01475.1 - 2.8e-27 94.6 1.9 2.8e-27 94.6 1.3 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY01475.1 - 1.7e-19 69.6 0.3 3.7e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 KFY01475.1 - 3.5e-06 26.8 13.2 3.5e-06 26.8 9.2 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F420_oxidored PF03807.12 KFY01475.1 - 0.021 15.2 1.4 0.23 11.8 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KFY01475.1 - 0.051 13.8 0.1 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.16 KFY01475.1 - 0.088 12.6 1.2 0.62 9.8 0.4 2.4 2 0 0 2 2 2 0 ThiF family MobB PF03205.9 KFY01475.1 - 0.088 12.5 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B 2-Hacid_dh_C PF02826.14 KFY01475.1 - 0.14 11.2 0.8 0.76 8.8 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SGL PF08450.7 KFY01483.1 - 7.5e-65 218.7 0.1 1e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KFY01483.1 - 0.072 13.1 1.3 1.5 9.1 0.0 3.3 4 0 0 4 4 4 0 Two component regulator propeller CAP_GLY PF01302.20 KFY01510.1 - 4.3e-16 58.3 0.3 9.5e-16 57.2 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.4 KFY01510.1 - 0.003 16.9 2.0 0.003 16.9 1.4 3.7 4 0 0 4 4 4 2 Vitamin-D-receptor interacting Mediator subunit 4 DUF3552 PF12072.3 KFY01510.1 - 0.01 15.0 2.8 0.01 15.0 1.9 3.2 2 1 0 3 3 2 0 Domain of unknown function (DUF3552) NPV_P10 PF05531.7 KFY01510.1 - 0.021 15.0 4.0 4.8 7.5 0.3 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 KFY01510.1 - 0.037 13.3 6.2 4.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) tRNA-synt_1d PF00750.14 KFY01510.1 - 0.058 12.2 1.8 0.096 11.4 1.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) BLOC1_2 PF10046.4 KFY01510.1 - 0.089 12.9 13.1 12 6.1 2.0 3.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.4 KFY01510.1 - 0.28 10.9 2.0 6.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein TPR_MLP1_2 PF07926.7 KFY01510.1 - 1 9.1 32.8 0.15 11.8 6.9 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KFY01510.1 - 1.1 7.6 24.2 0.038 12.4 5.5 2.5 1 1 2 3 3 3 0 AAA domain Spc7 PF08317.6 KFY01510.1 - 1.7 7.1 33.0 0.023 13.3 4.7 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein Pkip-1 PF06878.6 KFY01510.1 - 1.9 8.3 8.4 2.3 8.0 0.8 2.3 1 1 1 2 2 2 0 Pkip-1 protein Phage_GP20 PF06810.6 KFY01510.1 - 2.2 7.6 27.4 0.52 9.7 3.0 4.3 3 1 0 4 4 4 0 Phage minor structural protein GP20 Adeno_PIX PF03955.9 KFY01510.1 - 2.4 8.7 8.6 3 8.4 0.1 3.7 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Tup_N PF08581.5 KFY01510.1 - 4.6 7.5 22.9 1.9 8.7 0.9 4.4 4 1 1 5 5 5 0 Tup N-terminal TMF_DNA_bd PF12329.3 KFY01510.1 - 6.9 6.5 43.7 1.5 8.7 2.0 5.5 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 KFY01510.1 - 9 6.0 17.5 1.9 8.2 0.9 3.3 2 1 2 4 4 4 0 Laminin Domain II Nop14 PF04147.7 KFY01512.1 - 7.9e-261 867.6 16.8 1e-260 867.3 11.6 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.1 KFY01513.1 - 4.4e-20 71.0 2.7 1.8e-19 69.0 1.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KFY01513.1 - 1.8e-10 40.4 1.4 3.5e-10 39.4 1.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFY01513.1 - 0.00087 19.0 1.4 0.00087 19.0 1.0 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site PPR_3 PF13812.1 KFY01514.1 - 4.7e-05 23.3 1.0 0.13 12.5 0.1 5.0 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFY01514.1 - 0.0085 16.0 0.0 6.5 6.8 0.0 4.4 4 0 0 4 4 4 1 PPR repeat family ORC3_N PF07034.6 KFY01515.1 - 7.1e-45 153.4 3.8 2e-44 151.9 2.7 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Propep_M14 PF02244.11 KFY01515.1 - 0.088 12.4 0.7 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Carboxypeptidase activation peptide SLAC1 PF03595.12 KFY01516.1 - 3.5e-58 196.8 40.4 4e-58 196.6 28.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4492 PF14899.1 KFY01516.1 - 0.11 12.0 3.7 0.33 10.4 2.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) NPL4 PF05021.10 KFY01517.1 - 1.3e-126 421.8 0.0 1.7e-126 421.5 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KFY01517.1 - 2.1e-70 235.0 0.1 3.3e-70 234.4 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KFY01517.1 - 0.00018 21.7 0.0 0.00053 20.2 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 KFY01518.1 - 1.8e-79 265.5 0.0 2.1e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Tox-REase-5 PF15648.1 KFY01519.1 - 0.0053 17.0 0.2 0.0063 16.7 0.1 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 5 tRNA-synt_2d PF01409.15 KFY01520.1 - 5.1e-80 268.2 0.0 7.7e-80 267.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KFY01520.1 - 2.4e-05 23.2 0.2 0.00024 19.9 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KFY01520.1 - 2.6e-05 23.8 0.0 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) CPSase_L_D2 PF02786.12 KFY01521.1 - 8.1e-110 365.0 0.2 1.6e-83 279.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KFY01521.1 - 6.2e-42 142.2 0.0 1.6e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KFY01521.1 - 7.9e-38 130.0 0.2 6e-21 75.0 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KFY01521.1 - 1.3e-34 118.6 0.0 7.5e-17 61.4 0.0 2.8 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KFY01521.1 - 9.9e-24 83.6 0.0 4.2e-10 38.8 0.0 3.5 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFY01521.1 - 2.7e-19 69.1 0.1 1.3e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFY01521.1 - 5.2e-17 61.9 0.8 1.6e-08 34.2 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KFY01521.1 - 8.2e-11 41.7 0.1 1.1e-07 31.5 0.0 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KFY01521.1 - 1.8e-05 24.6 0.3 0.15 11.9 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain GARS_A PF01071.14 KFY01521.1 - 3.4e-05 23.4 0.4 0.024 14.1 0.1 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KFY01521.1 - 0.0014 17.8 0.1 0.13 11.4 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 KFY01521.1 - 0.017 15.0 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain Epimerase PF01370.16 KFY01521.1 - 0.038 13.4 0.0 0.53 9.6 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family EAP30 PF04157.11 KFY01521.1 - 0.16 11.1 0.0 0.61 9.2 0.0 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family DUF4315 PF14193.1 KFY01522.1 - 0.014 15.2 0.4 0.014 15.2 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4315) Dict-STAT-coil PF09267.5 KFY01522.1 - 0.22 11.7 5.8 0.91 9.7 0.4 3.1 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil Sec63 PF02889.11 KFY01523.1 - 4.3e-194 643.7 0.1 2.4e-107 358.8 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KFY01523.1 - 2e-50 170.5 0.0 4.5e-30 104.3 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KFY01523.1 - 3.7e-15 56.2 0.0 2.8e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFY01523.1 - 2e-10 40.3 0.0 7.9e-10 38.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFY01523.1 - 1.1e-05 25.6 0.2 0.0058 16.7 0.1 3.4 2 1 0 2 2 2 2 AAA domain PWWP PF00855.12 KFY01524.1 - 4.8e-13 49.1 0.3 4.8e-13 49.1 0.2 3.5 2 2 0 2 2 2 1 PWWP domain Methyltransf_2 PF00891.13 KFY01525.1 - 8.8e-23 80.7 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase UDPGT PF00201.13 KFY01525.1 - 0.00021 19.9 0.1 0.00047 18.8 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_hydro_61 PF03443.9 KFY01526.1 - 1.6e-74 250.3 0.4 1.9e-74 250.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BNR_2 PF13088.1 KFY01527.1 - 8.3e-06 25.2 0.7 4.8e-05 22.7 0.4 2.1 1 1 0 1 1 1 1 BNR repeat-like domain Big_3 PF07523.7 KFY01528.1 - 1.1e-08 35.0 0.7 2.5e-08 33.8 0.5 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) RicinB_lectin_2 PF14200.1 KFY01529.1 - 9.4e-28 96.6 3.7 8.2e-15 55.0 0.1 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like F5_F8_type_C PF00754.20 KFY01529.1 - 5.2e-08 32.7 0.3 5.2e-08 32.7 0.2 2.1 2 0 0 2 2 2 1 F5/8 type C domain RTC_insert PF05189.8 KFY01530.1 - 5.3e-31 106.6 0.1 9.8e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 KFY01530.1 - 1.6e-30 105.5 0.2 2.3e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase MRP_L53 PF10780.4 KFY01531.1 - 1.4e-19 69.7 1.0 2.9e-19 68.7 0.7 1.6 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 KFY01532.1 - 8.1e-14 51.0 2.4 1.1e-13 50.6 0.0 2.4 3 1 0 3 3 3 1 Sec20 Exonuc_VII_L PF02601.10 KFY01532.1 - 3.7 6.6 8.9 3.7 6.6 4.6 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit Mnd1 PF03962.10 KFY01532.1 - 8.8 5.9 7.8 2.8 7.5 2.8 2.1 2 0 0 2 2 2 0 Mnd1 family Abhydrolase_6 PF12697.2 KFY01533.1 - 1.9e-21 77.0 0.1 3.8e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01533.1 - 1.7e-10 40.8 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY01533.1 - 0.00025 20.6 0.0 0.02 14.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0261 PF06792.6 KFY01533.1 - 0.0032 16.0 0.1 0.0051 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Hydrolase_4 PF12146.3 KFY01533.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 KFY01533.1 - 0.041 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KFY01533.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 KFY01533.1 - 0.085 12.0 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 KFY01533.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2417 PF10329.4 KFY01534.1 - 1.1e-85 286.7 1.1 1.5e-85 286.3 0.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KFY01534.1 - 7.5e-08 32.5 0.2 1.6e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TMEM51 PF15345.1 KFY01534.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Sdh_cyt PF01127.17 KFY01534.1 - 6.9 6.5 17.7 92 2.9 4.7 3.4 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ABC2_membrane_3 PF12698.2 KFY01534.1 - 9.6 5.1 13.6 15 4.4 9.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA PF00004.24 KFY01535.1 - 1.8e-13 50.8 0.0 1.1e-12 48.2 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KFY01535.1 - 2.8e-12 46.4 0.0 5.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KFY01535.1 - 8.9e-12 44.4 0.0 1.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 KFY01535.1 - 2.9e-11 43.3 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA_22 PF13401.1 KFY01535.1 - 3.2e-06 27.3 0.1 0.00096 19.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFY01535.1 - 9e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY01535.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KFY01535.1 - 0.00022 21.2 0.2 0.0072 16.3 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KFY01535.1 - 0.00024 20.2 0.0 0.00057 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KFY01535.1 - 0.0046 16.1 0.0 0.37 9.9 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFY01535.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFY01535.1 - 0.0097 15.5 0.6 0.031 13.8 0.4 1.9 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KFY01535.1 - 0.016 14.6 0.3 0.27 10.6 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family DNA_pol3_delta PF06144.8 KFY01535.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TMP_2 PF06791.8 KFY01535.1 - 0.049 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_5 PF07728.9 KFY01535.1 - 0.051 13.2 0.1 0.75 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KFY01535.1 - 0.052 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFY01535.1 - 0.064 14.0 0.0 0.22 12.3 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KFY01535.1 - 0.067 12.7 0.0 0.69 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFY01535.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2974 PF11187.3 KFY01537.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) F-box PF00646.28 KFY01538.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY01538.1 - 0.007 16.0 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Nop25 PF09805.4 KFY01538.1 - 0.07 13.2 2.4 0.1 12.6 1.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DZR PF12773.2 KFY01538.1 - 0.81 9.5 5.6 1.4 8.7 2.3 2.3 2 1 0 2 2 2 0 Double zinc ribbon DUF2387 PF09526.5 KFY01538.1 - 1.5 8.7 4.5 52 3.8 0.0 3.4 3 1 1 4 4 4 0 Probable metal-binding protein (DUF2387) C1_4 PF07975.7 KFY01538.1 - 4.4 7.3 6.0 1 9.4 0.2 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain DOR PF14839.1 KFY01539.1 - 1.1 8.9 4.2 1.7 8.3 2.9 1.2 1 0 0 1 1 1 0 DOR family Pkinase PF00069.20 KFY01542.1 - 1.5e-36 125.9 0.0 1.2e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01542.1 - 2.7e-14 52.8 0.0 4.4e-13 48.9 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY01542.1 - 0.00018 21.3 0.1 0.00046 19.9 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFY01542.1 - 0.13 11.2 0.0 0.59 9.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Ank_2 PF12796.2 KFY01543.1 - 5.5e-14 52.2 0.0 0.0016 18.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFY01543.1 - 9e-13 48.0 0.0 9.6e-05 22.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFY01543.1 - 3.3e-11 42.4 2.1 0.062 13.1 0.0 6.8 6 1 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFY01543.1 - 1.7e-07 31.5 0.1 0.28 11.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01543.1 - 1.4e-06 27.9 1.5 6.2 7.3 0.0 7.2 7 0 0 7 7 7 1 Ankyrin repeat DUF4160 PF13711.1 KFY01543.1 - 0.048 13.5 0.2 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) AA_permease PF00324.16 KFY01545.1 - 3e-136 454.5 39.3 3.7e-136 454.2 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFY01545.1 - 8.8e-35 120.0 41.0 1.2e-34 119.5 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_5 PF00266.14 KFY01551.1 - 1.7e-25 89.5 0.0 2.8e-25 88.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 KFY01551.1 - 1.2e-19 70.2 0.0 2.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Sod_Fe_C PF02777.13 KFY01552.1 - 8.4e-12 44.8 0.0 5.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sugar_tr PF00083.19 KFY01558.1 - 4.4e-88 295.8 20.3 5.5e-88 295.5 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01558.1 - 2.6e-12 46.1 40.3 1.8e-10 40.0 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LVIVD PF08309.6 KFY01560.1 - 1.7e-12 46.0 1.6 0.089 11.7 0.0 5.4 5 0 0 5 5 5 4 LVIVD repeat Beta_propel PF09826.4 KFY01560.1 - 0.044 12.1 0.2 3.7 5.7 0.1 2.5 1 1 0 2 2 2 0 Beta propeller domain Abhydrolase_6 PF12697.2 KFY01562.1 - 3.4e-12 46.7 1.3 6e-12 45.9 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01562.1 - 5.9e-11 42.3 0.1 1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFY01562.1 - 0.00024 20.7 0.1 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFY01562.1 - 0.0014 18.1 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFY01562.1 - 0.032 14.0 0.1 0.081 12.7 0.1 1.7 1 1 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KFY01563.1 - 2.7e-38 131.5 0.0 3.1e-26 92.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFY01563.1 - 3.9e-08 33.4 0.0 9e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01563.1 - 5.6e-08 32.6 0.0 9.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY01563.1 - 1.5e-06 27.6 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.8 KFY01563.1 - 2.3e-05 23.9 0.0 0.00023 20.6 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFY01563.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KFY01563.1 - 0.027 13.7 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 KFY01563.1 - 0.11 12.1 0.1 0.66 9.6 0.0 2.0 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal F-box-like PF12937.2 KFY01564.1 - 0.00057 19.5 0.0 0.0023 17.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY01564.1 - 0.015 14.9 0.9 0.12 12.0 0.0 2.5 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 KFY01564.1 - 6.5 6.4 13.9 1.8 8.2 0.2 4.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) gag-asp_proteas PF13975.1 KFY01565.1 - 4.4e-07 29.6 0.0 0.00051 19.8 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFY01565.1 - 9.3e-07 29.2 0.0 0.00087 19.7 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.5 KFY01565.1 - 1.2e-05 24.8 0.2 0.0067 15.9 0.0 3.2 2 1 1 3 3 3 2 Aspartyl protease RVP PF00077.15 KFY01565.1 - 0.0023 17.8 0.0 3.2 7.7 0.0 3.2 3 0 0 3 3 3 2 Retroviral aspartyl protease zf-C2H2 PF00096.21 KFY01565.1 - 0.014 15.6 13.8 0.052 13.9 1.2 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY01565.1 - 8.1 7.0 15.0 0.4 11.1 1.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Rad51 PF08423.6 KFY01572.1 - 1.9e-20 72.8 0.0 3.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFY01572.1 - 5.8e-10 38.8 0.1 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFY01572.1 - 1.3e-07 30.9 0.0 3.2e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.16 KFY01572.1 - 2.8e-07 29.9 0.1 1.3e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 KFY01572.1 - 0.00062 19.9 0.0 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFY01572.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Pept_tRNA_hydro PF01195.14 KFY01572.1 - 0.27 10.7 0.0 0.42 10.0 0.0 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PAXNEB PF05625.6 KFY01572.1 - 0.27 10.0 0.5 0.43 9.3 0.3 1.2 1 0 0 1 1 1 0 PAXNEB protein FAD_binding_4 PF01565.18 KFY01573.1 - 8.6e-22 77.1 4.4 1.9e-21 76.0 3.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY01573.1 - 0.00092 19.0 0.4 0.0018 18.1 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KFY01575.1 - 1.2e-39 136.0 10.9 1.2e-39 136.0 7.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KFY01575.1 - 0.027 14.4 5.0 2.2 8.3 0.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2970 PF11174.3 KFY01575.1 - 0.08 12.5 0.1 0.08 12.5 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) NicO PF03824.11 KFY01575.1 - 0.79 8.9 10.6 2 7.6 1.9 2.4 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF1275 PF06912.6 KFY01575.1 - 1.2 8.2 16.5 3 6.9 0.3 4.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1275) NUDIX PF00293.23 KFY01576.1 - 4.6e-07 29.5 0.0 4.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain Aldo_ket_red PF00248.16 KFY01577.1 - 3.2e-52 177.1 0.0 4.6e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 KFY01577.1 - 5.8e-20 71.2 1.1 1.4e-19 70.0 0.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01577.1 - 9.9e-07 28.5 5.7 9.9e-07 28.5 3.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFY01577.1 - 4.1e-06 26.8 8.6 0.011 16.0 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY01577.1 - 0.00032 20.8 8.4 0.12 12.7 0.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFY01577.1 - 0.0015 18.6 0.8 0.0015 18.6 0.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain MFS_1 PF07690.11 KFY01578.1 - 3.3e-32 111.5 31.2 4.4e-32 111.1 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KFY01578.1 - 3.7e-23 82.1 0.0 5.4e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFY01578.1 - 4.5e-09 35.6 0.0 0.0007 18.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY01578.1 - 1.2e-05 24.3 0.0 6.3e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFY01578.1 - 0.00029 20.8 0.1 0.0011 18.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFY01578.1 - 0.00036 20.6 0.0 0.00083 19.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY01578.1 - 0.0014 17.1 0.0 0.012 14.1 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KFY01578.1 - 0.0037 16.4 0.1 0.16 10.9 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KFY01578.1 - 0.0089 16.4 0.5 0.035 14.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFY01578.1 - 0.059 13.3 0.1 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Ski_Sno PF02437.12 KFY01578.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 SKI/SNO/DAC family Zn_clus PF00172.13 KFY01579.1 - 1.5e-06 27.9 9.0 3.5e-06 26.8 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C_2 PF13410.1 KFY01579.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Beta-lactamase PF00144.19 KFY01580.1 - 1.3e-20 73.7 0.0 3.9e-20 72.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.13 KFY01609.1 - 7.8e-11 41.3 0.1 1.3e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1529 PF07485.6 KFY01609.1 - 0.2 11.3 0.5 0.35 10.6 0.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) Isochorismatase PF00857.15 KFY01618.1 - 4.5e-17 62.5 0.1 6.3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Voltage_CLC PF00654.15 KFY01620.1 - 3.9e-92 309.0 20.0 3.9e-92 309.0 13.9 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel WLM PF08325.5 KFY01634.1 - 1.2e-40 139.3 0.0 2e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KFY01634.1 - 4.2e-09 35.3 11.4 5.1e-08 31.8 0.6 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others SprT-like PF10263.4 KFY01634.1 - 0.007 16.0 0.2 0.055 13.1 0.0 2.3 2 1 0 2 2 2 1 SprT-like family DUF45 PF01863.12 KFY01634.1 - 0.054 13.2 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 HutP PF09021.6 KFY01634.1 - 0.082 13.1 0.5 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 HutP Herpes_LMP2 PF07415.6 KFY01634.1 - 2.4 6.6 6.7 3.4 6.1 4.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DZR PF12773.2 KFY01634.1 - 9 6.2 12.5 1.4e+02 2.3 8.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon CorA PF01544.13 KFY01635.1 - 3.4e-10 39.4 0.0 5.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Na_Ca_ex PF01699.19 KFY01635.1 - 0.1 12.2 0.9 0.17 11.4 0.6 1.3 1 0 0 1 1 1 0 Sodium/calcium exchanger protein TPR_12 PF13424.1 KFY01636.1 - 6.7e-09 35.5 14.6 1.4e-06 28.1 1.3 4.8 3 1 3 6 6 6 2 Tetratricopeptide repeat DUF2225 PF09986.4 KFY01636.1 - 1.7e-05 24.4 1.9 4e-05 23.1 1.1 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 KFY01636.1 - 3.4e-05 23.4 13.2 0.15 12.0 0.2 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFY01636.1 - 0.00015 21.3 5.7 0.0071 15.9 2.1 2.9 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KFY01636.1 - 0.0059 16.1 5.8 0.8 9.4 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KFY01636.1 - 0.0082 16.2 0.0 0.052 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KFY01636.1 - 0.021 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KFY01636.1 - 0.03 14.3 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TPR_8 PF13181.1 KFY01636.1 - 0.038 13.7 3.7 10 6.1 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_19 PF13245.1 KFY01636.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TPR_16 PF13432.1 KFY01636.1 - 0.075 13.7 5.1 5.4 7.8 1.4 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFY01636.1 - 0.35 10.7 4.9 1.2 9.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Amidase PF01425.16 KFY01639.1 - 4.4e-29 101.6 1.0 9.4e-29 100.5 0.7 1.5 1 0 0 1 1 1 1 Amidase Actin PF00022.14 KFY01651.1 - 5.3e-137 456.4 0.0 6e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFY01651.1 - 0.028 13.0 0.0 4.9 5.6 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein MBOAT PF03062.14 KFY01652.1 - 5e-45 154.0 21.7 5e-45 154.0 15.0 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pam16 PF03656.8 KFY01659.1 - 1.9e-36 124.6 0.7 2.2e-36 124.4 0.5 1.0 1 0 0 1 1 1 1 Pam16 RCC1 PF00415.13 KFY01660.1 - 7.8e-58 192.5 11.2 3.9e-09 36.5 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFY01660.1 - 2.9e-34 115.9 32.5 8e-09 34.8 0.0 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MIP-T3 PF10243.4 KFY01660.1 - 0.0015 17.1 20.4 0.0018 16.8 14.1 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SOBP PF15279.1 KFY01660.1 - 2.2 8.5 12.4 3.5 7.9 8.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.12 KFY01660.1 - 6.3 5.5 4.5 9.5 4.9 3.1 1.2 1 0 0 1 1 1 0 Presenilin HEAT PF02985.17 KFY01661.1 - 6.7e-28 94.2 9.8 8.6e-06 25.4 0.0 9.8 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KFY01661.1 - 1.3e-27 95.4 14.1 1.2e-14 54.2 0.0 10.6 9 2 3 12 12 12 5 HEAT-like repeat HEAT_2 PF13646.1 KFY01661.1 - 2.2e-23 82.3 0.1 2.6e-08 34.0 0.0 7.2 4 3 2 6 6 6 5 HEAT repeats Cnd1 PF12717.2 KFY01661.1 - 1.8e-12 47.5 0.7 0.025 14.4 0.0 6.1 6 1 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KFY01661.1 - 2.5e-08 34.2 0.0 0.12 12.7 0.0 6.1 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KFY01661.1 - 2e-07 30.5 0.0 0.093 12.0 0.0 6.7 7 1 0 8 8 8 1 CLASP N terminal MMS19_C PF12460.3 KFY01661.1 - 1.3e-06 27.4 1.4 0.48 9.0 0.0 4.8 4 1 0 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.18 KFY01661.1 - 1.3e-05 24.8 4.2 0.42 10.5 0.0 6.6 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KFY01661.1 - 5.8e-05 22.9 1.2 0.0011 18.7 0.0 3.8 4 1 0 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KFY01661.1 - 0.00011 20.6 0.0 1.6 6.9 0.1 4.1 2 2 2 4 4 4 1 Adaptin N terminal region RIX1 PF08167.7 KFY01661.1 - 0.15 11.6 2.4 8.5 6.0 0.0 4.2 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 KFY01661.1 - 0.38 11.3 3.6 10 6.9 0.0 5.0 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat N2227 PF07942.7 KFY01663.1 - 2.6e-98 328.2 0.0 3.3e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KFY01663.1 - 2.1e-05 24.2 0.0 5.7e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KFY01664.1 - 6.2e-27 94.5 3.9 1.4e-26 93.3 2.7 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY01664.1 - 1.4e-21 77.3 0.2 4.4e-21 75.7 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY01664.1 - 1.7e-12 47.3 1.2 1.7e-12 47.3 0.8 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFY01665.1 - 4.4e-07 30.0 0.0 5.2e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFY01665.1 - 8.3e-05 21.6 0.1 0.01 14.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KFY01665.1 - 0.014 14.2 0.1 0.053 12.4 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KFY01665.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFY01665.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KFY01675.1 - 6.1e-06 26.2 0.3 8.7e-06 25.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Macoilin PF09726.4 KFY01679.1 - 0.5 8.5 17.0 0.66 8.1 11.8 1.1 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 KFY01679.1 - 3.4 6.1 8.7 4.6 5.7 6.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.1 KFY01679.1 - 5.1 6.7 11.8 8.2 6.1 8.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CAF-1_p150 PF11600.3 KFY01679.1 - 8.4 5.6 43.8 14 5.0 30.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop14 PF04147.7 KFY01692.1 - 3e-05 22.1 6.9 3.4e-05 22.0 4.8 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KFY01692.1 - 0.034 12.1 4.4 0.032 12.2 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 KFY01692.1 - 2.3 7.1 4.5 2.8 6.8 3.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YqfQ PF14181.1 KFY01692.1 - 9.1 6.2 7.0 14 5.6 4.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein Mitofilin PF09731.4 KFY01693.1 - 0.043 12.4 7.5 0.053 12.1 5.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAP1 PF08601.5 KFY01693.1 - 5.6 6.5 43.9 10 5.6 30.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4551 PF15087.1 KFY01693.1 - 6.2 5.0 24.2 8.3 4.6 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) KAR9 PF08580.5 KFY01693.1 - 8.2 4.5 44.7 12 4.0 31.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Gtr1_RagA PF04670.7 KFY01694.1 - 2e-91 305.2 0.0 3.2e-91 304.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 60KD_IMP PF02096.15 KFY01694.1 - 2.1e-30 105.9 0.7 3.6e-30 105.1 0.5 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1275 PF06912.6 KFY01694.1 - 2.8e-26 92.0 7.0 2.8e-26 92.0 4.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1275) Arf PF00025.16 KFY01694.1 - 3.8e-06 26.2 0.0 7.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFY01694.1 - 9.9e-06 25.0 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFY01694.1 - 7.7e-05 22.6 0.0 0.00027 20.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFY01694.1 - 9.7e-05 22.8 0.0 0.00027 21.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KFY01694.1 - 0.0045 16.4 0.4 0.023 14.1 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 KFY01694.1 - 0.023 13.6 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFY01694.1 - 0.038 14.2 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KFY01694.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PEP_mutase PF13714.1 KFY01695.1 - 4.6e-45 153.7 0.2 5.8e-45 153.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFY01695.1 - 1e-23 83.4 0.5 1.6e-23 82.7 0.3 1.3 1 0 0 1 1 1 1 Isocitrate lyase family DUF1297 PF06973.7 KFY01695.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) TGT PF01702.13 KFY01696.1 - 2.2e-37 128.6 0.0 3.1e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.14 KFY01697.1 - 2e-21 75.7 0.2 3.2e-21 75.1 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Dmrt1 PF12374.3 KFY01704.1 - 0.021 15.1 2.9 0.071 13.4 0.1 2.4 1 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Ank_2 PF12796.2 KFY01713.1 - 4.9e-47 158.2 0.1 1.6e-17 63.5 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFY01713.1 - 3.3e-30 101.1 0.0 1.3e-06 28.0 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.25 KFY01713.1 - 1.4e-28 97.2 0.2 4.2e-07 29.4 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFY01713.1 - 9.6e-27 92.8 0.0 1.4e-09 38.1 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY01713.1 - 2.9e-24 84.5 0.3 7.5e-10 38.7 0.0 7.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) HET PF06985.6 KFY01713.1 - 2.9e-19 69.6 0.0 7.8e-19 68.2 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Vasculin PF15337.1 KFY01714.1 - 0.1 13.0 0.5 0.61 10.6 0.0 2.2 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Metallophos PF00149.23 KFY01715.1 - 2e-10 40.3 0.8 4.1e-10 39.3 0.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFY01715.1 - 7.3e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Elicitin PF00964.12 KFY01715.1 - 0.014 15.3 2.1 0.82 9.6 0.0 2.5 2 0 0 2 2 2 0 Elicitin Zn_clus PF00172.13 KFY01716.1 - 0.00028 20.7 7.5 0.00053 19.8 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2 PF00703.16 KFY01717.1 - 3.6e-10 40.2 0.0 7.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFY01717.1 - 1.7e-06 27.7 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.19 KFY01718.1 - 5.5e-74 249.3 19.7 6.4e-74 249.1 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01718.1 - 7.7e-36 123.5 39.8 2.7e-28 98.6 15.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.1 KFY01718.1 - 0.051 13.5 3.0 0.37 10.7 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF377 PF04041.8 KFY01719.1 - 1.1e-51 175.4 0.0 1.4e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KFY01719.1 - 8.2e-09 34.9 0.9 1e-05 24.8 0.1 3.7 2 1 0 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFY01719.1 - 2.5e-08 33.6 0.7 8.3e-06 25.3 0.0 2.8 2 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain DUF377 PF04041.8 KFY01720.1 - 2.6e-55 187.3 0.0 3.5e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KFY01720.1 - 2.2e-10 40.1 2.0 0.00012 21.2 0.0 4.0 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFY01720.1 - 5.4e-10 39.1 3.6 1.7e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Zn_clus PF00172.13 KFY01721.1 - 4.4e-07 29.7 12.0 7.8e-07 28.9 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 KFY01722.1 - 5.9e-33 114.0 0.0 1.8e-32 112.4 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY01722.1 - 2.6e-08 34.1 0.1 3.8e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KFY01722.1 - 5e-05 23.2 0.0 8.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KFY01722.1 - 0.0014 17.4 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KFY01722.1 - 0.06 13.7 0.2 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KFY01722.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GFA PF04828.9 KFY01723.1 - 5.4e-21 74.3 0.0 7.6e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFY01723.1 - 0.048 12.8 0.4 0.048 12.8 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KFY01723.1 - 0.065 12.7 0.9 0.065 12.7 0.6 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 KFY01723.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.9 2 1 0 2 2 2 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 KFY01723.1 - 0.11 12.3 1.2 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.1 KFY01723.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.2 3 0 0 3 3 3 0 Nudix N-terminal DUF1936 PF09151.5 KFY01723.1 - 0.23 11.0 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Lar_restr_allev PF14354.1 KFY01723.1 - 1.4 9.2 5.5 11 6.3 0.2 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Isochorismatase PF00857.15 KFY01724.1 - 1.8e-43 148.4 0.0 2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.6 KFY01724.1 - 0.11 12.4 0.0 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) DUF3533 PF12051.3 KFY01725.1 - 2.5e-94 316.1 12.8 3e-94 315.8 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ECH PF00378.15 KFY01726.1 - 2.3e-27 95.7 0.0 3e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family LRRC37AB_C PF14914.1 KFY01726.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Glyco_hydro_20 PF00728.17 KFY01727.1 - 2.5e-75 253.8 0.0 4.2e-75 253.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFY01727.1 - 9.7e-12 45.6 0.0 2.9e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFY01727.1 - 0.00089 19.7 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Corona_NS2A PF05213.7 KFY01727.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein Aminotran_3 PF00202.16 KFY01739.1 - 1.5e-96 323.2 0.0 1.9e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_ab PF00006.20 KFY01740.1 - 1e-60 204.9 0.0 1.6e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HMGL-like PF00682.14 KFY01740.1 - 1.6e-39 136.0 0.0 3.5e-39 134.8 0.0 1.6 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab_C PF00306.22 KFY01740.1 - 2.7e-14 53.5 0.2 5.7e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFY01740.1 - 3.3e-11 43.2 1.0 3.3e-11 43.2 0.7 2.4 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain WPP PF13943.1 KFY01740.1 - 0.074 13.2 0.2 1.9 8.7 0.0 2.7 3 0 0 3 3 3 0 WPP domain HLH PF00010.21 KFY01748.1 - 7.5e-09 35.1 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 KFY01748.1 - 0.0057 15.8 0.5 0.0072 15.4 0.3 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family A_deaminase_N PF08451.6 KFY01748.1 - 0.082 12.9 0.7 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal ADH_zinc_N PF00107.21 KFY01749.1 - 8.9e-20 70.5 0.0 1.5e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY01749.1 - 1.9e-05 25.5 0.0 4.8e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase tRNA-synt_2b PF00587.20 KFY01750.1 - 1.6e-44 151.5 0.0 2.5e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFY01750.1 - 0.00053 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain adh_short PF00106.20 KFY01752.1 - 6.5e-27 94.4 3.8 8e-27 94.1 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY01752.1 - 3.9e-19 69.3 0.0 4.9e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY01752.1 - 4.7e-09 36.1 2.4 7e-09 35.6 1.7 1.1 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.1 KFY01753.1 - 8.4e-20 70.8 0.0 1.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFY01753.1 - 2.1e-11 44.1 0.0 4.5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFY01753.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 KFY01754.1 - 2.8e-26 91.9 0.1 5.1e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01754.1 - 8.4e-08 31.9 13.7 1.6e-07 31.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_TAF50 PF03326.8 KFY01754.1 - 0.0083 15.1 14.2 0.013 14.4 9.8 1.2 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) YrhK PF14145.1 KFY01774.1 - 0.11 12.2 1.9 0.46 10.1 1.3 1.9 1 1 0 1 1 1 0 YrhK-like protein Zn_clus PF00172.13 KFY01777.1 - 4e-06 26.6 8.5 7.8e-06 25.7 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.5 KFY01778.1 - 4.6e-61 206.3 2.7 4.6e-61 206.3 1.8 2.2 2 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 KFY01778.1 - 2.4e-08 34.1 0.6 0.0022 18.2 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY01778.1 - 1.9e-06 27.6 4.5 0.047 13.6 0.0 4.8 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY01778.1 - 0.01 15.4 5.3 0.28 10.8 0.1 4.4 3 1 1 4 4 4 0 TPR repeat TPR_2 PF07719.12 KFY01778.1 - 0.72 9.9 12.0 0.99 9.4 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFY01779.1 - 7.9e-36 122.2 0.1 7.5e-09 35.8 0.0 5.3 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01779.1 - 9.5e-34 113.5 10.3 3.6e-06 26.5 0.0 9.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 KFY01779.1 - 9.7e-33 111.9 1.6 1.3e-09 38.2 0.0 7.3 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY01779.1 - 1.5e-25 88.6 1.6 2.3e-07 30.8 0.2 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01779.1 - 1.1e-24 83.9 4.6 1.2e-05 25.0 0.0 8.1 8 1 0 8 8 8 5 Ankyrin repeat CtaG_Cox11 PF04442.9 KFY01780.1 - 7.5e-57 191.3 0.0 1.4e-56 190.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 C2 PF00168.25 KFY01780.1 - 4.8e-21 74.3 0.0 6.7e-16 57.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain Sec6 PF06046.8 KFY01781.1 - 8.9e-161 535.7 4.3 1.4e-160 535.1 3.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 DASH_Duo1 PF08651.5 KFY01781.1 - 0.056 13.0 2.7 0.12 12.0 0.3 2.9 3 1 0 3 3 3 0 DASH complex subunit Duo1 Vps53_N PF04100.7 KFY01781.1 - 0.059 12.1 11.0 0.17 10.6 1.8 2.8 1 1 1 3 3 3 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.15 KFY01782.1 - 7.4e-15 54.2 0.3 1.2e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e NUC173 PF08161.7 KFY01783.1 - 9.6e-77 256.8 0.6 1.7e-74 249.5 0.0 3.2 3 0 0 3 3 3 2 NUC173 domain DUF2508 PF10704.4 KFY01783.1 - 0.055 13.6 3.9 0.24 11.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Vac14_Fab1_bd PF12755.2 KFY01783.1 - 0.1 12.9 0.8 6.5 7.2 0.0 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RNA_pol_Rpb1_7 PF04990.7 KFY01783.1 - 2.8 7.6 8.2 1 9.0 0.8 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 7 TGF_beta_GS PF08515.7 KFY01821.1 - 0.058 12.7 0.5 0.22 10.8 0.0 2.1 1 1 0 1 1 1 0 Transforming growth factor beta type I GS-motif Aa_trans PF01490.13 KFY01822.1 - 5.8e-52 176.5 39.4 7.2e-52 176.2 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.5 KFY01822.1 - 0.18 11.0 1.0 0.31 10.2 0.7 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF3753 PF12575.3 KFY01822.1 - 6.1 6.7 10.4 2.1 8.2 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Dynactin PF12455.3 KFY01823.1 - 1.3e-90 303.0 7.7 1.3e-90 303.0 5.4 2.6 2 1 0 2 2 2 1 Dynein associated protein CAP_GLY PF01302.20 KFY01823.1 - 1.4e-21 75.9 0.3 2.4e-21 75.2 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain NPV_P10 PF05531.7 KFY01823.1 - 5.9 7.2 25.2 23 5.3 0.1 6.9 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein CLN3 PF02487.12 KFY01824.1 - 6.7e-105 351.1 12.2 6.1e-103 344.7 8.4 2.0 1 1 0 1 1 1 1 CLN3 protein Rxt3 PF08642.5 KFY01825.1 - 1.4e-27 96.2 0.0 5.2e-27 94.3 0.0 2.1 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KFY01825.1 - 6.7e-05 22.7 0.0 0.00092 19.1 0.0 2.2 2 0 0 2 2 2 1 LCCL domain CAF-1_p150 PF11600.3 KFY01825.1 - 0.76 9.1 28.9 3.4 6.9 20.0 2.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 KFY01825.1 - 5.7 4.5 4.6 9.4 3.7 3.2 1.2 1 0 0 1 1 1 0 Ycf1 HET PF06985.6 KFY01826.1 - 5.5e-21 75.1 8.3 1.2e-17 64.3 0.3 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Ribonuclease_T2 PF00445.13 KFY01827.1 - 8.1e-46 156.0 0.1 8.1e-46 156.0 0.1 1.4 2 0 0 2 2 2 1 Ribonuclease T2 family Pec_lyase_C PF00544.14 KFY01828.1 - 1.4e-41 142.1 9.8 2.3e-41 141.5 6.8 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFY01828.1 - 0.00023 20.9 11.7 0.00045 19.9 7.3 1.9 1 1 1 2 2 2 2 Right handed beta helix region FAD_binding_4 PF01565.18 KFY01829.1 - 1.8e-20 72.8 3.3 1.8e-20 72.8 2.3 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KFY01829.1 - 0.00047 20.0 0.1 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.21 KFY01830.1 - 9.9e-72 241.4 0.0 8.1e-71 238.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFY01830.1 - 1.2e-49 169.4 0.0 2.2e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFY01830.1 - 3.9e-32 110.5 0.9 9.5e-32 109.3 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KFY01830.1 - 5.3e-08 33.0 1.1 1.3e-07 31.7 0.8 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFY01830.1 - 5.8e-06 25.4 0.1 1.4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KFY01830.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lactamase_B PF00753.22 KFY01831.1 - 2.2e-22 79.6 0.3 2.8e-22 79.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFY01831.1 - 6.8e-06 25.7 0.0 9.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFY01831.1 - 0.0046 16.6 0.1 0.0073 16.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain tRNA-synt_2b PF00587.20 KFY01831.1 - 0.066 12.7 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) AflR PF08493.5 KFY01833.1 - 2.8e-14 52.8 7.5 4.9e-14 52.0 5.2 1.4 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KFY01833.1 - 4.5e-06 26.4 12.5 8.2e-06 25.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmpp129 PF10272.4 KFY01833.1 - 6.7 5.3 6.5 10 4.6 4.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF3425 PF11905.3 KFY01834.1 - 8e-26 90.5 0.0 3.2e-25 88.5 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.20 KFY01835.1 - 5.7e-18 65.3 0.1 8.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY01835.1 - 5.1e-09 36.0 0.1 8.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFY01835.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFY01835.1 - 0.00095 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY01835.1 - 0.0035 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TIR-like PF10137.4 KFY01835.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Ald_Xan_dh_C2 PF02738.13 KFY01836.1 - 7.6e-192 638.4 0.9 1.1e-191 637.9 0.6 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KFY01836.1 - 1.1e-47 161.6 0.0 2.5e-47 160.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KFY01836.1 - 6.8e-33 112.6 0.2 2.6e-32 110.8 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 KFY01836.1 - 1.7e-29 102.1 0.0 4.5e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KFY01836.1 - 7.2e-29 99.5 0.1 1.5e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KFY01836.1 - 3.7e-08 33.0 0.2 2e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fic PF02661.13 KFY01837.1 - 3.4e-14 53.3 0.0 1.7e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 Fic/DOC family DUF1034 PF06280.7 KFY01855.1 - 0.091 13.1 0.1 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) 6PF2K PF01591.13 KFY01856.1 - 5.8e-82 274.0 0.1 7.4e-82 273.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFY01856.1 - 1.3e-29 103.3 0.0 2.3e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFY01856.1 - 2.3e-07 30.7 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFY01856.1 - 1.5e-05 24.4 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFY01856.1 - 0.00043 21.0 0.3 0.053 14.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Atracotoxin PF05353.6 KFY01856.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Delta Atracotoxin WSC PF01822.14 KFY01857.1 - 4e-70 231.7 67.4 1.5e-19 69.6 7.2 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 KFY01857.1 - 7.3e-32 110.3 0.0 1.8e-30 105.8 0.0 2.7 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KFY01857.1 - 2.7e-24 85.0 0.6 3.4e-23 81.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KFY01857.1 - 0.0012 18.5 1.9 2.2 8.1 0.1 4.1 3 0 0 3 3 3 1 Galactose oxidase, central domain PS_Dcarbxylase PF02666.10 KFY01859.1 - 4e-50 169.9 0.0 4.7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PTPLA PF04387.9 KFY01860.1 - 1.5e-44 151.3 4.9 2.2e-44 150.7 3.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ank_2 PF12796.2 KFY01862.1 - 7.3e-68 224.9 8.8 5.6e-20 71.4 0.1 6.9 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) GMC_oxred_N PF00732.14 KFY01862.1 - 1.1e-50 172.5 0.2 1.6e-50 171.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Ank PF00023.25 KFY01862.1 - 6.1e-40 133.0 33.7 4.1e-08 32.6 0.1 14.3 13 1 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KFY01862.1 - 3e-39 132.7 14.8 8.8e-12 45.2 0.1 9.9 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY01862.1 - 3.2e-32 109.8 20.1 6.9e-11 42.0 0.2 11.6 6 2 6 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01862.1 - 3.3e-30 101.0 15.2 0.00053 19.9 0.0 13.5 12 1 1 13 13 13 5 Ankyrin repeat HATPase_c PF02518.21 KFY01862.1 - 2.4e-24 85.1 0.0 6e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KFY01862.1 - 3.8e-20 72.2 0.0 1.1e-13 51.4 0.0 2.8 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 KFY01862.1 - 5.1e-17 61.6 0.2 1.2e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KFY01862.1 - 5.9e-15 55.2 0.3 1.3e-14 54.1 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.19 KFY01862.1 - 4.3e-13 49.0 0.0 4.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KFY01862.1 - 3.9e-11 42.9 0.0 0.00059 19.8 0.0 3.1 3 0 0 3 3 3 2 PAS fold DAO PF01266.19 KFY01862.1 - 5.6e-08 32.0 1.7 0.0068 15.3 0.4 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY01862.1 - 2e-05 23.6 4.7 0.0003 19.7 0.4 3.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY01862.1 - 0.0005 20.0 0.1 0.005 16.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY01862.1 - 0.0015 18.5 0.8 0.0051 16.7 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFY01862.1 - 0.0018 17.4 0.1 0.0031 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KFY01862.1 - 0.054 12.5 0.3 0.14 11.2 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Shigella_OspC PF06128.6 KFY01862.1 - 0.31 10.4 0.2 1 8.7 0.0 1.9 2 0 0 2 2 2 0 Shigella flexneri OspC protein Defensin_big PF14862.1 KFY01863.1 - 0.009 16.0 0.1 0.026 14.5 0.1 1.8 1 1 0 1 1 1 1 Big defensin ET PF01684.11 KFY01863.1 - 0.43 10.6 2.3 1.3 9.1 1.8 1.7 1 1 1 2 2 2 0 ET module Fungal_trans PF04082.13 KFY01864.1 - 3.7e-17 62.0 1.1 5.9e-17 61.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 KFY01865.1 - 9.5e-56 188.6 0.0 1.4e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.11 KFY01866.1 - 9.3e-33 113.3 26.6 9.3e-33 113.3 18.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.16 KFY01867.1 - 2e-37 128.8 4.2 5.3e-37 127.4 1.6 2.4 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 KFY01867.1 - 1.4e-07 30.5 17.3 1.4e-07 30.5 12.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1469 PF07332.6 KFY01867.1 - 9.2 6.0 8.3 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Methyltransf_2 PF00891.13 KFY01868.1 - 2.8e-29 102.0 0.0 4.5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KFY01868.1 - 0.0052 16.5 1.2 0.015 15.0 0.1 2.3 2 0 0 2 2 2 1 Dimerisation domain HTH_IclR PF09339.5 KFY01868.1 - 0.039 13.5 0.1 0.088 12.4 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain GPI-anchored PF10342.4 KFY01869.1 - 8.6e-11 42.1 0.1 8.6e-11 42.1 0.1 1.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.5 KFY01869.1 - 0.00043 19.5 0.1 0.00043 19.5 0.1 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF3301 PF11743.3 KFY01869.1 - 0.12 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) MGC-24 PF05283.6 KFY01869.1 - 2 8.1 11.6 3.1 7.5 8.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Patatin PF01734.17 KFY01870.1 - 1.2e-25 90.6 0.0 2e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3337 PF11816.3 KFY01873.1 - 1.3e-83 281.1 0.0 7.3e-80 268.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) DDHD PF02862.12 KFY01873.1 - 1.5e-45 155.7 1.4 2.2e-27 96.3 0.0 3.4 2 1 1 3 3 3 2 DDHD domain WD40 PF00400.27 KFY01873.1 - 1.9e-28 97.2 9.7 2.6e-07 30.2 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat FAD_binding_3 PF01494.14 KFY01875.1 - 1.8e-73 247.6 0.0 2.3e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KFY01875.1 - 2e-41 141.4 0.0 3.2e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KFY01875.1 - 0.00056 20.2 0.0 0.018 15.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY01875.1 - 0.0059 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFY01875.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY01875.1 - 0.016 15.1 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY01875.1 - 0.026 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KFY01875.1 - 0.027 13.9 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 KFY01875.1 - 0.033 14.4 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain DAO PF01266.19 KFY01875.1 - 0.037 12.9 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFY01875.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_C48 PF02902.14 KFY01876.1 - 8e-26 90.9 0.0 1.7e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DSPc PF00782.15 KFY01877.1 - 1.2e-28 99.3 0.0 6.1e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFY01877.1 - 0.0002 20.8 0.0 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Endonuclease_NS PF01223.18 KFY01894.1 - 2.6e-52 177.4 0.0 3.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Ferric_reduct PF01794.14 KFY01900.1 - 0.00012 22.1 12.2 0.0018 18.3 1.6 1.9 1 1 1 2 2 2 2 Ferric reductase like transmembrane component TraH PF06122.6 KFY01901.1 - 4.6 5.9 14.2 4.9 5.8 7.6 2.1 2 0 0 2 2 2 0 Conjugative relaxosome accessory transposon protein Mfa2 PF08842.5 KFY01902.1 - 0.12 11.6 0.2 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 DUF3723 PF12520.3 KFY01904.1 - 6e-112 374.7 0.0 1e-101 340.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.20 KFY01905.1 - 1.7e-09 37.1 0.0 1.6e-08 34.0 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01905.1 - 4.1e-08 32.6 0.0 1.3e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase mRNA_cap_enzyme PF01331.14 KFY01926.1 - 1.2e-46 158.7 0.0 1.7e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KFY01926.1 - 8.8e-24 83.8 0.3 1.4e-23 83.1 0.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KFY01926.1 - 7.2e-05 22.2 0.0 0.0044 16.3 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain HEAT PF02985.17 KFY01928.1 - 8.7e-08 31.6 0.3 0.23 11.6 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KFY01928.1 - 1.6e-06 28.3 4.7 0.0054 16.9 1.3 5.1 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KFY01928.1 - 0.1 13.1 0.1 0.1 13.1 0.1 5.6 7 0 0 7 7 7 0 HEAT-like repeat Nop14 PF04147.7 KFY01928.1 - 2.2 6.1 14.0 4.3 5.1 9.7 1.4 1 0 0 1 1 1 0 Nop14-like family WAC_Acf1_DNA_bd PF10537.4 KFY01944.1 - 3.2e-38 129.9 0.3 1.2e-37 128.2 0.0 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KFY01944.1 - 2.9e-17 62.1 1.7 5.1e-17 61.3 1.1 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KFY01944.1 - 2.2e-11 43.2 0.5 4.8e-11 42.1 0.4 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KFY01944.1 - 4.1e-05 23.2 0.1 0.00012 21.7 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PMAIP1 PF15150.1 KFY01944.1 - 0.04 13.6 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced WHIM3 PF15614.1 KFY01944.1 - 0.064 13.0 0.0 0.3 10.8 0.0 2.2 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 Ribosomal_L30_N PF08079.7 KFY01949.1 - 2.4e-24 85.1 19.7 2.4e-24 85.1 13.7 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KFY01949.1 - 1.5e-18 66.1 1.4 1.5e-18 66.1 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PIR PF00399.14 KFY01964.1 - 0.45 9.9 10.3 0.3 10.5 1.6 2.6 2 0 0 2 2 2 0 Yeast PIR protein repeat Mito_carr PF00153.22 KFY01965.1 - 4.5e-54 180.1 1.9 1.4e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clr5 PF14420.1 KFY01966.1 - 1.1e-18 66.9 4.4 1.9e-18 66.1 3.0 1.4 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_3 PF00933.16 KFY01967.1 - 1.2e-60 205.0 0.0 1.8e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFY01967.1 - 2.9e-44 151.2 0.0 4.9e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFY01967.1 - 3.9e-08 33.1 0.0 9.5e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 KFY01969.1 - 4.1e-22 78.1 4.0 8.3e-22 77.1 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY01969.1 - 0.00013 21.7 0.1 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KFY01970.1 - 9e-30 103.5 19.6 9e-30 103.5 13.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.2 KFY01970.1 - 0.032 14.0 7.6 0.067 13.0 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) TauD PF02668.11 KFY01971.1 - 2.1e-51 175.1 0.1 2.5e-51 174.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.3 KFY01972.1 - 2.9e-54 184.1 0.1 5.2e-54 183.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01972.1 - 2.1e-07 30.7 21.4 4.7e-05 23.1 6.1 3.3 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFY01972.1 - 2.6e-07 30.5 12.0 0.003 17.7 0.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFY01972.1 - 0.00022 21.3 3.0 0.00022 21.3 2.1 4.6 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFY01972.1 - 0.0012 19.0 16.6 0.015 15.5 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KFY01972.1 - 0.035 14.3 3.2 6.9 7.0 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFY01972.1 - 0.93 9.7 5.1 16 5.8 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_3 PF00933.16 KFY01973.1 - 1.3e-64 218.0 0.0 1.8e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFY01973.1 - 1.4e-43 149.0 0.0 2e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain WSC PF01822.14 KFY01973.1 - 2.5e-16 59.3 9.7 5.4e-16 58.2 6.7 1.6 1 0 0 1 1 1 1 WSC domain Amidohydro_1 PF01979.15 KFY01974.1 - 4.7e-56 190.8 0.2 5.9e-56 190.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFY01974.1 - 1.3e-14 54.9 0.1 5.7e-10 39.6 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KFY01974.1 - 7.2e-13 48.5 0.0 8.1e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFY01974.1 - 2.9e-08 33.4 0.0 7.1e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KFY01974.1 - 0.00057 18.8 0.0 0.0018 17.2 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.15 KFY01975.1 - 1.3e-61 208.2 31.2 3e-59 200.4 21.6 3.0 1 1 0 1 1 1 1 Permease family ABC2_membrane PF01061.19 KFY01976.1 - 9.6e-30 103.3 29.4 1.3e-29 102.8 20.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFY01976.1 - 1.4e-25 90.2 0.0 2.2e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY01976.1 - 7.2e-07 29.4 0.0 0.0046 16.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFY01976.1 - 8.6e-06 25.2 0.1 0.0003 20.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFY01976.1 - 3.9e-05 22.8 0.1 6.4e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFY01976.1 - 9e-05 22.5 0.1 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY01976.1 - 0.0025 17.9 0.1 0.0094 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY01976.1 - 0.0063 16.2 0.4 0.015 15.0 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFY01976.1 - 0.0073 15.7 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein Rad17 PF03215.10 KFY01976.1 - 0.0089 14.7 0.0 0.012 14.2 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KFY01976.1 - 0.0094 16.1 0.1 0.041 14.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 KFY01976.1 - 0.015 14.5 0.0 0.073 12.2 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KFY01976.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFY01976.1 - 0.028 15.2 0.1 0.068 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KFY01976.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.1 KFY01976.1 - 0.032 13.2 0.0 0.36 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 KFY01976.1 - 0.038 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 KFY01976.1 - 0.042 12.7 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KFY01976.1 - 0.042 13.3 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KFY01976.1 - 0.055 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFY01976.1 - 0.057 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KFY01976.1 - 0.058 12.8 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 KFY01976.1 - 0.08 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KFY01976.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFY01976.1 - 0.1 12.1 0.4 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFY01976.1 - 0.1 12.8 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KFY01976.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 KFY01976.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KFY01976.1 - 0.14 12.0 0.4 0.28 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain Fungal_trans PF04082.13 KFY01977.1 - 4.8e-06 25.6 0.0 8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01977.1 - 0.0042 16.9 1.4 0.0075 16.1 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFY01978.1 - 2.3e-16 60.1 0.0 3.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 KFY01978.1 - 1.4e-06 27.6 0.2 1.7e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KFY01978.1 - 0.022 14.4 0.1 0.053 13.1 0.0 1.7 1 1 0 1 1 1 0 KR domain GST_N_3 PF13417.1 KFY01979.1 - 2.7e-10 40.2 0.0 5.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFY01979.1 - 2.7e-07 30.4 0.0 5.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFY01979.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFY01979.1 - 0.021 15.2 0.0 0.094 13.2 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.17 KFY01980.1 - 8.5e-79 265.2 0.0 9.8e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MyTH4 PF00784.12 KFY01980.1 - 0.032 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 MyTH4 domain MFS_1 PF07690.11 KFY01982.1 - 6.1e-18 64.6 67.1 5.1e-15 55.0 27.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 KFY01998.1 - 0.015 14.3 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter UPF0060 PF02694.10 KFY02003.1 - 0.00035 20.5 1.7 0.00057 19.8 1.2 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family TcpE PF12648.2 KFY02003.1 - 0.2 11.8 2.3 0.35 11.0 1.6 1.4 1 0 0 1 1 1 0 TcpE family Arteri_Gl PF00951.13 KFY02003.1 - 0.61 9.6 6.0 0.89 9.1 4.1 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Pkinase PF00069.20 KFY02005.1 - 0.00043 19.5 0.0 0.00084 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TSC22 PF01166.13 KFY02007.1 - 0.0045 16.9 0.2 11 6.0 0.0 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family Sporozoite_P67 PF05642.6 KFY02007.1 - 0.0048 14.8 0.0 0.0095 13.8 0.0 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen Filament PF00038.16 KFY02007.1 - 0.0076 15.7 12.0 0.009 15.5 0.8 3.0 2 1 0 3 3 3 1 Intermediate filament protein DUF4515 PF14988.1 KFY02007.1 - 0.0081 15.8 0.2 0.0081 15.8 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4515) TMF_TATA_bd PF12325.3 KFY02007.1 - 0.014 15.1 12.4 0.035 13.8 0.3 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 KFY02007.1 - 0.025 13.0 2.3 0.91 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF148 PF02520.12 KFY02007.1 - 0.076 12.8 0.1 2.4 7.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF904 PF06005.7 KFY02007.1 - 0.13 12.5 6.6 6.8 7.0 0.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF904) ApoO PF09769.4 KFY02007.1 - 0.15 11.7 0.6 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein O Seryl_tRNA_N PF02403.17 KFY02007.1 - 0.17 11.8 4.3 6.5 6.8 0.1 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FH2 PF02181.18 KFY02007.1 - 0.21 10.4 3.5 11 4.7 0.0 3.1 2 1 1 3 3 3 0 Formin Homology 2 Domain WEMBL PF05701.6 KFY02007.1 - 0.44 8.9 5.6 13 4.0 0.2 3.0 3 0 0 3 3 3 0 Weak chloroplast movement under blue light ADIP PF11559.3 KFY02007.1 - 0.66 9.8 10.5 2.1 8.2 1.0 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2383 PF09537.5 KFY02007.1 - 1.2 9.4 3.8 18 5.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF2383) PhoU PF01895.14 KFY02007.1 - 1.3 9.5 5.5 2.5 8.6 0.2 3.3 3 1 0 3 3 3 0 PhoU domain Lebercilin PF15619.1 KFY02007.1 - 1.5 8.2 9.7 0.1 12.0 0.6 3.0 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 KFY02007.1 - 4 6.9 12.2 11 5.5 1.3 3.3 2 2 2 4 4 4 0 IncA protein DUF3552 PF12072.3 KFY02007.1 - 7.4 5.7 12.8 0.12 11.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) WD40 PF00400.27 KFY02009.1 - 1.4e-140 452.7 38.1 5.3e-14 51.4 0.2 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat Nup160 PF11715.3 KFY02009.1 - 2.1e-24 85.6 42.3 0.016 13.3 0.1 10.2 1 1 9 10 10 10 10 Nucleoporin Nup120/160 NACHT PF05729.7 KFY02009.1 - 2.4e-09 37.0 0.0 5.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.1 KFY02009.1 - 8.6e-08 31.6 26.4 0.16 11.0 0.2 9.4 2 1 7 10 10 10 4 Neuroblastoma-amplified sequence, N terminal DUF1258 PF06869.7 KFY02009.1 - 9.1e-07 28.2 3.8 1.7 7.6 0.0 6.5 1 1 6 8 8 8 1 Protein of unknown function (DUF1258) AAA_16 PF13191.1 KFY02009.1 - 3e-05 24.0 0.0 0.00012 22.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain WXG100 PF06013.7 KFY02009.1 - 0.00069 19.5 13.4 86 3.2 0.0 9.1 9 2 0 9 9 9 0 Proteins of 100 residues with WXG DUF1797 PF08796.5 KFY02009.1 - 0.0053 16.5 0.0 51 3.8 0.0 4.8 4 1 1 5 5 4 0 Protein of unknown function (DUF1797) AAA_22 PF13401.1 KFY02009.1 - 0.0098 16.0 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFY02009.1 - 0.016 15.4 0.2 0.61 10.2 0.0 3.3 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFY02009.1 - 0.041 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase FlxA PF14282.1 KFY02009.1 - 0.08 12.8 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 FlxA-like protein AAA_19 PF13245.1 KFY02009.1 - 0.086 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 KFY02009.1 - 0.09 12.4 0.1 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_MLP1_2 PF07926.7 KFY02009.1 - 0.13 11.9 0.7 0.44 10.2 0.5 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CFEM PF05730.6 KFY02014.1 - 9.8e-15 54.1 14.0 1.6e-14 53.4 9.7 1.3 1 0 0 1 1 1 1 CFEM domain PC_rep PF01851.17 KFY02015.1 - 7.8e-46 151.8 13.3 1.7e-08 34.2 0.0 9.0 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFY02015.1 - 7.1e-19 67.8 0.2 2e-13 50.4 0.0 5.4 3 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KFY02015.1 - 1.1e-08 35.2 0.0 2.4e-05 24.6 0.0 4.8 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 KFY02015.1 - 7.7e-08 31.7 4.9 0.95 9.7 0.0 6.2 7 0 0 7 7 7 3 HEAT repeat DUF1546 PF07571.8 KFY02015.1 - 0.088 12.9 0.1 15 5.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) mRNA_triPase PF02940.10 KFY02016.1 - 4e-56 190.1 0.1 6.2e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_20 PF00728.17 KFY02017.1 - 7.6e-99 331.1 0.9 6.1e-98 328.2 0.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Pkinase PF00069.20 KFY02017.1 - 1.6e-43 148.7 0.0 6e-43 146.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02017.1 - 2.9e-31 108.4 0.0 4.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glycohydro_20b2 PF14845.1 KFY02017.1 - 6.6e-21 75.2 0.0 2e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFY02017.1 - 0.00013 22.4 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Kinase-like PF14531.1 KFY02017.1 - 0.017 14.1 0.0 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KFY02017.1 - 0.08 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFY02017.1 - 0.6 8.8 0.0 1 8.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Acyl_transf_3 PF01757.17 KFY02018.1 - 1e-29 103.5 23.8 1.8e-21 76.3 8.0 2.1 2 0 0 2 2 2 2 Acyltransferase family Cation_ATPase_C PF00689.16 KFY02018.1 - 1.6 8.2 8.0 7.6 6.0 0.5 3.1 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus SET PF00856.23 KFY02020.1 - 5.6e-10 39.7 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 SET domain Meleagrin PF08189.6 KFY02020.1 - 0.0032 16.8 0.4 0.0078 15.6 0.3 1.7 1 0 0 1 1 1 1 Meleagrin/Cygnin family TPR_11 PF13414.1 KFY02020.1 - 0.0046 16.5 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 TPR repeat Cep57_MT_bd PF06657.8 KFY02021.1 - 1.4e-27 95.3 0.1 1.4e-27 95.3 0.1 5.2 6 0 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KFY02021.1 - 1.9e-09 37.3 7.0 1.9e-09 37.3 4.8 3.4 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 NmrA PF05368.8 KFY02021.1 - 4.2e-09 35.9 0.0 1.7e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family HALZ PF02183.13 KFY02021.1 - 1.2 8.9 15.7 0.1 12.3 1.9 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper FtsL PF04999.8 KFY02021.1 - 6.5 6.5 12.3 1.1 9.0 1.0 3.0 3 0 0 3 3 3 0 Cell division protein FtsL SKG6 PF08693.5 KFY02022.1 - 1.9e-06 27.0 0.1 4.1e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KFY02022.1 - 0.017 13.3 0.1 0.017 13.3 0.1 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 KFY02022.1 - 0.017 14.9 2.1 0.023 14.5 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HET PF06985.6 KFY02025.1 - 2.2e-06 27.8 0.3 1.9e-05 24.8 0.2 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.7 KFY02026.1 - 2.4e-08 33.6 0.1 2.4e-07 30.4 0.0 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY02026.1 - 7.6e-07 28.7 0.3 2.7e-06 26.9 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase FrhB_FdhB_N PF04422.8 KFY02026.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Pyr_redox_2 PF07992.9 KFY02028.1 - 4.6e-25 88.6 4.5 7e-14 52.1 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFY02028.1 - 2.1e-21 75.9 0.0 7.5e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFY02028.1 - 6.5e-20 71.3 3.5 1.8e-16 60.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY02028.1 - 1.1e-08 35.3 0.3 4.6e-07 30.1 0.0 2.9 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY02028.1 - 4.3e-08 32.4 12.1 0.00054 18.9 2.5 3.8 3 1 0 3 3 3 3 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KFY02028.1 - 2.2e-06 27.3 0.6 0.0086 15.6 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KFY02028.1 - 1.4e-05 24.1 3.4 3.9 6.2 0.0 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFY02028.1 - 1.5e-05 24.3 10.0 0.0035 16.4 2.5 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KFY02028.1 - 0.00025 21.2 0.1 0.57 10.4 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding XdhC_C PF13478.1 KFY02028.1 - 0.0065 16.7 0.1 0.6 10.4 0.0 2.7 3 0 0 3 3 3 1 XdhC Rossmann domain NAD_binding_8 PF13450.1 KFY02028.1 - 0.025 14.6 5.3 6.8 6.7 0.2 3.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KFY02028.1 - 0.032 13.8 0.1 0.032 13.8 0.0 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KFY02028.1 - 0.11 11.5 0.8 1.2 8.1 0.3 2.4 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 KFY02028.1 - 0.14 10.9 15.5 0.41 9.4 3.5 4.2 3 1 2 5 5 5 0 FAD binding domain HI0933_like PF03486.9 KFY02028.1 - 0.56 8.6 6.8 3.4 6.0 2.0 3.1 3 1 1 4 4 4 0 HI0933-like protein Trp_halogenase PF04820.9 KFY02028.1 - 1.3 7.5 4.2 1.1 7.8 0.7 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Grp1_Fun34_YaaH PF01184.14 KFY02029.1 - 2e-30 105.6 20.7 2.7e-30 105.2 14.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3464 PF11947.3 KFY02029.1 - 0.24 10.8 0.6 0.53 9.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ada_Zn_binding PF02805.11 KFY02030.1 - 4.8e-25 86.9 8.3 8e-25 86.2 5.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KFY02030.1 - 1.9e-07 30.7 0.0 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KFY02030.1 - 4.4e-06 26.7 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFY02030.1 - 0.069 13.3 0.4 0.18 12.0 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Cu-oxidase_2 PF07731.9 KFY02039.1 - 1.9e-36 124.6 0.2 3.6e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cation_efflux PF01545.16 KFY02040.1 - 2.4e-71 240.1 0.0 3.3e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family MFS_1 PF07690.11 KFY02042.1 - 5e-29 101.1 34.1 5e-29 101.1 23.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily CbtB PF09489.5 KFY02043.1 - 2.5 8.0 4.8 3.8 7.4 3.3 1.5 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) UCR_Fe-S_N PF10399.4 KFY02043.1 - 3 7.1 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Acyl-CoA_dh_M PF02770.14 KFY02044.1 - 5e-06 25.9 0.0 1.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFY02044.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HTH_23 PF13384.1 KFY02045.1 - 0.00043 19.8 0.2 0.0011 18.4 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_psq PF05225.11 KFY02045.1 - 0.00053 19.4 0.1 0.0009 18.7 0.1 1.5 1 1 0 1 1 1 1 helix-turn-helix, Psq domain UPF0122 PF04297.9 KFY02045.1 - 0.0025 17.7 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_19 PF12844.2 KFY02045.1 - 0.0052 16.8 0.2 0.033 14.2 0.0 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.7 KFY02045.1 - 0.0068 15.9 0.1 0.074 12.6 0.0 2.1 1 1 1 2 2 2 1 HTH DNA binding domain HTH_40 PF14493.1 KFY02045.1 - 0.0074 16.4 0.1 0.011 15.8 0.1 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.5 KFY02045.1 - 0.0077 15.7 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.7 KFY02045.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Sigma-70, region 4 SpoIIID PF12116.3 KFY02045.1 - 0.0089 15.9 0.1 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 Stage III sporulation protein D Sigma70_r4 PF04545.11 KFY02045.1 - 0.016 14.4 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 KFY02045.1 - 0.021 14.3 3.7 0.055 13.0 0.2 2.5 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_28 PF13518.1 KFY02045.1 - 0.021 14.7 0.2 0.057 13.4 0.0 1.8 2 1 0 2 2 1 0 Helix-turn-helix domain TetR_N PF00440.18 KFY02045.1 - 0.026 14.1 0.2 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_7 PF02796.10 KFY02045.1 - 0.048 13.5 0.4 0.048 13.5 0.3 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.17 KFY02045.1 - 0.062 13.1 0.7 0.29 10.9 0.1 2.0 1 1 1 2 2 2 0 Helix-turn-helix Terminase_5 PF06056.7 KFY02045.1 - 0.072 12.6 0.4 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.2 KFY02045.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Phage_AlpA PF05930.7 KFY02045.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) CENP-B_N PF04218.8 KFY02045.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_20 PF12840.2 KFY02045.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.14 KFY02045.1 - 0.13 11.9 0.2 0.22 11.2 0.0 1.5 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB MerR PF00376.18 KFY02045.1 - 0.18 11.3 1.0 8.4 6.0 0.0 2.6 2 0 0 2 2 2 0 MerR family regulatory protein bZIP_1 PF00170.16 KFY02046.1 - 6.8e-06 25.9 2.5 1.1e-05 25.2 1.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFY02046.1 - 0.0016 18.2 6.2 0.003 17.3 4.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFY02046.1 - 1.4 9.2 6.4 0.82 10.0 2.9 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor F-box-like PF12937.2 KFY02047.1 - 2.2e-07 30.5 0.1 5.2e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY02047.1 - 0.00026 20.5 0.1 0.00079 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain DDE_3 PF13358.1 KFY02048.1 - 5.2e-17 61.9 0.0 8.8e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KFY02048.1 - 3.4e-07 30.2 0.8 1e-06 28.7 0.0 2.3 2 1 1 3 3 3 1 Transposase Sigma70_r4_2 PF08281.7 KFY02048.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.5 KFY02048.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_40 PF14493.1 KFY02048.1 - 0.007 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 KFY02048.1 - 0.015 14.9 0.2 0.069 12.8 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain TetR_N PF00440.18 KFY02048.1 - 0.039 13.6 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Sigma70_r4 PF04545.11 KFY02048.1 - 0.04 13.2 0.0 0.12 11.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 KFY02048.1 - 0.082 12.3 0.0 0.33 10.3 0.0 2.1 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.10 KFY02048.1 - 0.1 12.4 0.4 0.59 10.0 0.1 2.4 3 0 0 3 3 2 0 Helix-turn-helix domain of resolvase zf-C3HC4 PF00097.20 KFY02048.1 - 0.11 12.1 0.7 0.38 10.4 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HTH_10 PF04967.7 KFY02048.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain UPF0122 PF04297.9 KFY02048.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Zn_Tnp_IS1595 PF12760.2 KFY02048.1 - 0.22 11.3 2.5 0.35 10.7 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFY02048.1 - 0.26 10.8 2.2 7.6 6.1 0.0 2.7 2 0 0 2 2 2 0 A2L zinc ribbon domain MerR PF00376.18 KFY02048.1 - 9.8 5.8 7.2 3.1 7.4 0.0 2.9 3 0 0 3 3 3 0 MerR family regulatory protein Ras PF00071.17 KFY02049.1 - 2.3e-46 157.1 0.0 2.8e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY02049.1 - 3.8e-13 49.9 0.0 5.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY02049.1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gp-FAR-1 PF05823.7 KFY02049.1 - 0.021 14.8 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Pyr_redox_3 PF13738.1 KFY02050.1 - 3.2e-24 86.1 0.0 5.6e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFY02050.1 - 3.3e-12 45.9 0.0 1.2e-09 37.5 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFY02050.1 - 1.6e-09 36.5 0.0 1.9e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFY02050.1 - 2.8e-06 27.3 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY02050.1 - 0.00051 20.0 0.1 0.0017 18.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFY02050.1 - 0.0016 17.3 0.1 0.024 13.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KFY02050.1 - 0.0022 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 KFY02050.1 - 0.019 14.7 0.5 2 8.1 0.2 3.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFY02050.1 - 0.023 15.0 0.1 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY02050.1 - 0.058 11.8 0.7 2.6 6.3 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.19 KFY02050.1 - 0.066 12.0 0.1 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase AAA PF00004.24 KFY02063.1 - 9e-18 64.7 0.0 1.8e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFY02063.1 - 5.4e-05 23.3 0.1 0.00032 20.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFY02063.1 - 0.00024 20.8 0.0 0.00046 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFY02063.1 - 0.00049 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFY02063.1 - 0.00055 19.0 0.4 0.019 13.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFY02063.1 - 0.00091 20.0 0.0 0.0039 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KFY02063.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY02063.1 - 0.0064 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFY02063.1 - 0.017 15.0 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFY02063.1 - 0.033 13.3 0.7 0.06 12.4 0.1 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFY02063.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KFY02063.1 - 0.071 12.5 0.1 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 KFY02063.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 KFY02063.1 - 0.086 12.3 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFY02063.1 - 0.12 11.8 0.1 0.4 10.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 KFY02063.1 - 0.12 11.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 KFY02063.1 - 0.15 11.8 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Taq-exonuc PF09281.5 KFY02075.1 - 0.0069 16.5 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Taq polymerase, exonuclease PGA2 PF07543.7 KFY02075.1 - 0.0078 16.0 0.2 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF4337 PF14235.1 KFY02075.1 - 0.16 11.8 0.6 0.17 11.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF972 PF06156.8 KFY02077.1 - 0.064 13.6 0.1 0.083 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 KFY02077.1 - 0.38 10.6 8.3 0.22 11.3 1.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper PHO4 PF01384.15 KFY02079.1 - 4.5e-113 377.2 12.3 5.3e-113 376.9 8.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF2670 PF10875.3 KFY02080.1 - 0.062 13.3 0.5 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) Pyr_redox_3 PF13738.1 KFY02082.1 - 2e-21 76.9 0.1 4.5e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY02082.1 - 1.8e-17 62.7 0.4 4.9e-17 61.3 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY02082.1 - 2.6e-10 40.1 0.0 8.8e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY02082.1 - 2.2e-06 26.8 0.1 0.0036 16.2 0.0 2.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFY02082.1 - 1.1e-05 24.6 0.1 7.4e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFY02082.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY02082.1 - 0.0026 17.5 0.1 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KFY02082.1 - 0.038 13.0 0.6 0.074 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 KFY02082.1 - 0.17 9.9 0.3 2.5 6.1 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MFS_1 PF07690.11 KFY02083.1 - 4.9e-23 81.4 24.0 6.9e-23 80.9 16.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KFY02084.1 - 2.5e-31 108.6 26.6 2.5e-31 108.6 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.15 KFY02085.1 - 3.4e-62 210.3 0.0 4.6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NMO PF03060.10 KFY02085.1 - 0.023 13.8 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase ABC_membrane PF00664.18 KFY02086.1 - 1.3e-36 126.4 11.9 1.8e-36 125.9 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFY02086.1 - 5.2e-35 120.7 0.0 9.5e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY02086.1 - 2e-07 31.2 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFY02086.1 - 3.4e-06 26.4 0.0 0.0012 18.1 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFY02086.1 - 3.4e-05 23.8 0.0 0.00022 21.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFY02086.1 - 0.00014 22.6 0.0 0.00031 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFY02086.1 - 0.00025 20.2 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KFY02086.1 - 0.00044 20.1 0.0 0.0044 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFY02086.1 - 0.0011 19.1 0.0 0.0079 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFY02086.1 - 0.0027 17.1 0.0 0.0075 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KFY02086.1 - 0.0031 17.0 0.1 0.008 15.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KFY02086.1 - 0.0053 16.9 0.0 0.034 14.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KFY02086.1 - 0.0062 16.4 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KFY02086.1 - 0.018 15.3 0.0 0.061 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFY02086.1 - 0.019 14.3 0.0 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFY02086.1 - 0.033 14.1 0.1 0.12 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFY02086.1 - 0.043 12.9 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFY02086.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 KFY02086.1 - 0.061 12.0 0.0 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MBOAT_2 PF13813.1 KFY02086.1 - 0.062 13.3 0.2 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family AAA_33 PF13671.1 KFY02086.1 - 0.066 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KFY02086.1 - 0.07 13.0 0.3 0.5 10.3 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KFY02086.1 - 0.073 13.5 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 KFY02086.1 - 0.074 12.7 0.3 0.27 10.9 0.0 2.1 3 0 0 3 3 1 0 NACHT domain AAA_24 PF13479.1 KFY02086.1 - 0.083 12.4 0.3 0.23 11.0 0.0 2.1 2 1 0 2 2 1 0 AAA domain ABC_ATPase PF09818.4 KFY02086.1 - 0.1 11.1 0.0 7.5 5.0 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 KFY02086.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 KFY02086.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.23 KFY02087.1 - 3.2e-11 42.9 4.1 1.2e-10 41.1 2.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFY02087.1 - 3.7e-09 36.6 0.0 5.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2204 PF09970.4 KFY02088.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) AAA PF00004.24 KFY02090.1 - 7.3e-28 97.4 0.1 1.4e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFY02090.1 - 5.8e-06 25.9 0.1 1.4e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KFY02090.1 - 7e-06 25.2 0.0 1.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 KFY02090.1 - 1.2e-05 24.9 0.0 0.0033 17.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY02090.1 - 4.7e-05 23.4 0.2 0.0001 22.3 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY02090.1 - 8.5e-05 22.7 0.7 0.00043 20.4 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFY02090.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFY02090.1 - 0.00035 19.4 0.0 0.00055 18.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 KFY02090.1 - 0.0014 18.7 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.9 KFY02090.1 - 0.0025 17.7 0.0 0.024 14.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 KFY02090.1 - 0.0029 18.4 0.0 0.01 16.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KFY02090.1 - 0.0044 16.4 0.4 0.013 14.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFY02090.1 - 0.007 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFY02090.1 - 0.012 15.0 0.2 0.033 13.5 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 KFY02090.1 - 0.013 14.5 0.5 1.7 7.7 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.1 KFY02090.1 - 0.014 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 KFY02090.1 - 0.02 14.8 0.1 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFY02090.1 - 0.024 14.3 0.4 0.067 12.8 0.3 1.7 1 1 0 1 1 1 0 NACHT domain ArsA_ATPase PF02374.10 KFY02090.1 - 0.024 13.6 0.3 0.07 12.1 0.2 1.7 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_14 PF13173.1 KFY02090.1 - 0.025 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFY02090.1 - 0.025 14.2 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KFY02090.1 - 0.03 13.4 0.0 0.076 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KFY02090.1 - 0.04 13.8 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KFY02090.1 - 0.047 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KFY02090.1 - 0.051 12.5 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KFY02090.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFY02090.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CbiA PF01656.18 KFY02090.1 - 0.14 11.5 0.1 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytokin_check_N PF10407.4 KFY02091.1 - 2e-05 24.1 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Velvet PF11754.3 KFY02092.1 - 1.8e-69 233.3 0.0 2.9e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Fer2_3 PF13085.1 KFY02093.1 - 5e-30 103.5 0.0 8.3e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KFY02093.1 - 6.3e-10 39.2 6.5 6.3e-10 39.2 4.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFY02093.1 - 6.2e-09 35.7 4.8 6.2e-09 35.7 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFY02093.1 - 0.00017 21.9 10.2 0.00024 21.4 1.1 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFY02093.1 - 0.00017 21.7 3.7 0.043 14.0 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFY02093.1 - 0.00058 19.6 5.0 0.00058 19.6 3.4 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KFY02093.1 - 0.0073 16.0 0.4 0.0073 16.0 0.3 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KFY02093.1 - 0.0099 16.2 6.6 0.0099 16.2 4.6 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KFY02093.1 - 0.88 10.0 3.6 2.1 8.7 0.9 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KFY02093.1 - 3.8 8.1 7.8 1 9.9 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Evr1_Alr PF04777.8 KFY02094.1 - 1.1e-28 99.0 0.1 1.5e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Med27 PF11571.3 KFY02094.1 - 0.07 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 27 R3H PF01424.17 KFY02095.1 - 1.4e-13 50.2 0.0 2.7e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KFY02095.1 - 0.0031 17.4 14.3 0.0031 17.4 9.9 8.5 10 0 0 10 10 10 5 NF-X1 type zinc finger TPR_11 PF13414.1 KFY02096.1 - 4.6e-08 32.5 4.3 6.3e-08 32.1 0.2 2.7 2 1 1 3 3 3 2 TPR repeat Zn_clus PF00172.13 KFY02096.1 - 1.4e-06 28.0 10.2 2.8e-06 27.1 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.1 KFY02096.1 - 0.0027 18.3 3.3 1.5 9.5 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFY02096.1 - 0.0033 17.9 1.7 0.078 13.6 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFY02096.1 - 0.0078 16.0 0.7 0.72 9.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 KFY02096.1 - 0.011 14.3 0.1 0.021 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_1 PF00515.23 KFY02096.1 - 0.021 14.4 1.2 1.8 8.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02096.1 - 0.25 11.3 5.4 1.6 8.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 KFY02097.1 - 0.77 8.7 5.5 3.3 6.6 2.9 2.2 1 1 0 1 1 1 0 E1-E2 ATPase Lipase_GDSL PF00657.17 KFY02098.1 - 1.6e-21 77.2 0.0 1.9e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFY02098.1 - 4e-21 75.9 0.0 5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_61 PF03443.9 KFY02099.1 - 7e-68 228.6 1.0 1e-67 228.1 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aminotran_4 PF01063.14 KFY02099.1 - 2.2e-22 79.6 0.0 2.9e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Nif11 PF07862.6 KFY02099.1 - 0.23 11.4 0.0 0.56 10.1 0.0 1.7 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function TPR_12 PF13424.1 KFY02114.1 - 2.1e-21 75.6 4.3 1.3e-08 34.6 0.0 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 KFY02114.1 - 5.3e-11 41.9 0.0 1.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain CorA PF01544.13 KFY02114.1 - 7.3e-07 28.4 0.1 1.7e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.2 KFY02114.1 - 6.4e-05 22.9 0.0 0.00024 21.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_11 PF13414.1 KFY02114.1 - 0.00019 20.9 3.7 0.41 10.3 0.0 4.3 4 0 0 4 4 4 1 TPR repeat TPR_10 PF13374.1 KFY02114.1 - 0.00036 20.3 7.8 0.051 13.5 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PGAP1 PF07819.8 KFY02114.1 - 0.0015 18.1 0.1 0.0042 16.6 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein TPR_16 PF13432.1 KFY02114.1 - 0.0067 17.0 3.1 11 6.8 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF676 PF05057.9 KFY02114.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_22 PF13401.1 KFY02114.1 - 0.02 15.0 0.0 0.07 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 KFY02114.1 - 0.022 14.5 0.0 0.08 12.7 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family LTD PF00932.14 KFY02114.1 - 0.12 12.4 0.1 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Lamin Tail Domain TPR_2 PF07719.12 KFY02114.1 - 0.2 11.6 10.3 38 4.5 0.4 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFY02114.1 - 0.58 9.8 3.9 58 3.5 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat HAD_2 PF13419.1 KFY02115.1 - 1.6e-08 34.9 0.0 6e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY02115.1 - 3.3e-07 29.9 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFY02115.1 - 0.0008 19.8 0.0 0.0012 19.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CN_hydrolase PF00795.17 KFY02117.1 - 3.8e-12 45.9 0.0 6.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Vma12 PF11712.3 KFY02117.1 - 0.0039 16.9 0.0 0.0099 15.5 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_hydro_18 PF00704.23 KFY02118.1 - 7.2e-46 157.1 3.0 1.5e-45 156.1 1.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFY02118.1 - 5.9e-08 32.4 0.2 0.017 15.0 0.1 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KFY02118.1 - 0.0054 16.6 3.4 0.0054 16.6 2.4 3.5 4 0 0 4 4 4 1 Chitin recognition protein DUF3015 PF11220.3 KFY02119.1 - 1.9 8.1 4.9 0.7 9.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3015) WSC PF01822.14 KFY02120.1 - 4.5e-46 154.6 38.0 1.2e-16 60.4 5.0 3.8 3 0 0 3 3 3 3 WSC domain LysM PF01476.15 KFY02120.1 - 6.3e-05 22.7 0.6 0.0018 18.1 0.4 2.5 2 0 0 2 2 2 1 LysM domain Chromo PF00385.19 KFY02122.1 - 1.1e-19 69.8 4.3 7.3e-10 38.3 0.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_6 PF13921.1 KFY02122.1 - 3.7e-05 23.7 0.7 0.0001 22.3 0.5 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mtf2_C PF14061.1 KFY02122.1 - 0.5 10.3 1.8 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Telomerase_RBD PF12009.3 KFY02124.1 - 5.3e-43 146.1 0.2 1.5e-42 144.7 0.1 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KFY02124.1 - 5.2e-17 61.9 0.0 5.1e-16 58.6 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 KFY02125.1 - 2.6e-35 121.9 0.2 1.3e-34 119.6 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 KFY02125.1 - 2.2e-08 33.9 1.8 2.2e-08 33.9 1.3 2.0 2 0 0 2 2 2 1 BAR domain Abhydrolase_5 PF12695.2 KFY02126.1 - 2.9e-25 88.6 0.0 4.3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY02126.1 - 2.3e-17 63.6 0.0 6.3e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KFY02126.1 - 6.3e-09 34.7 0.1 0.0025 16.3 0.0 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KFY02126.1 - 1.4e-08 34.6 0.0 5.7e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFY02126.1 - 1.2e-06 27.8 0.0 5.1e-06 25.8 0.0 2.0 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFY02126.1 - 1.3e-06 28.0 0.4 0.03 13.7 0.1 2.6 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 KFY02126.1 - 7.1e-06 25.6 0.0 2.3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFY02126.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KFY02126.1 - 0.00013 21.7 0.0 0.0052 16.5 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF818 PF05677.7 KFY02126.1 - 0.00019 20.3 0.1 0.00026 19.8 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 KFY02126.1 - 0.00048 19.4 0.0 0.046 12.9 0.0 2.5 3 0 0 3 3 3 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KFY02126.1 - 0.0012 18.3 0.0 0.28 10.5 0.0 2.6 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KFY02126.1 - 0.0042 16.9 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KFY02126.1 - 0.0058 16.2 0.4 0.032 13.8 0.4 2.0 2 1 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 KFY02126.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KFY02126.1 - 0.054 12.9 0.0 0.76 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Peptidase_S28 PF05577.7 KFY02126.1 - 0.058 11.9 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 zf-LYAR PF08790.6 KFY02127.1 - 7.7e-15 54.2 1.2 7.7e-15 54.2 0.8 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 KFY02127.1 - 0.039 14.3 0.6 0.08 13.3 0.4 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger Pex2_Pex12 PF04757.9 KFY02128.1 - 4.1e-43 147.4 7.1 5.4e-43 147.0 4.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KFY02128.1 - 1.7e-11 43.7 8.6 3e-11 42.9 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFY02128.1 - 1.8e-11 43.8 7.8 3e-11 43.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY02128.1 - 7.7e-10 38.2 6.4 1.3e-09 37.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFY02128.1 - 2.6e-08 33.3 8.0 3.9e-08 32.8 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY02128.1 - 3.4e-08 33.0 5.3 5.4e-08 32.4 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFY02128.1 - 2.1e-06 27.4 7.7 3.7e-06 26.6 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFY02128.1 - 0.00023 21.2 8.1 0.00072 19.6 5.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KFY02128.1 - 0.0012 18.6 5.1 0.0024 17.5 3.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFY02128.1 - 0.0036 16.9 6.4 0.0092 15.6 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KFY02128.1 - 0.0075 15.7 1.3 0.016 14.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFY02128.1 - 0.071 12.7 7.4 0.13 11.8 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KFY02128.1 - 1.7 8.5 7.0 5.3 6.9 4.9 1.8 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 KFY02129.1 - 2.9e-96 322.5 7.6 3.3e-96 322.3 5.3 1.0 1 0 0 1 1 1 1 EXS family DUF2422 PF10337.4 KFY02130.1 - 9.8e-17 60.8 0.0 5.1e-16 58.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KFY02130.1 - 3.3e-10 39.9 0.4 7.7e-09 35.4 0.2 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KFY02130.1 - 5.1e-10 39.3 19.7 9.9e-10 38.4 13.6 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like EST1_DNA_bind PF10373.4 KFY02133.1 - 9.8e-10 38.1 1.1 3.2e-09 36.4 0.8 1.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Peptidase_C14 PF00656.17 KFY02134.1 - 1.1e-32 113.7 0.0 1.7e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.21 KFY02134.1 - 2.1e-07 30.8 2.5 0.007 16.6 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY02134.1 - 1.4e-06 28.1 3.9 0.0095 16.2 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Peptidase_C13 PF01650.13 KFY02134.1 - 0.085 12.1 0.1 0.21 10.8 0.0 1.7 1 1 1 2 2 2 0 Peptidase C13 family bZIP_1 PF00170.16 KFY02135.1 - 0.14 12.1 3.7 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 bZIP transcription factor PIP5K PF01504.13 KFY02137.1 - 0.021 13.9 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Pirin_C PF05726.8 KFY02137.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Pirin C-terminal cupin domain Glyco_hydro_18 PF00704.23 KFY02144.1 - 4.1e-47 161.2 4.8 7.1e-47 160.5 3.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFY02144.1 - 6e-08 32.4 0.2 0.017 14.9 0.1 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KFY02144.1 - 0.0056 16.6 3.4 0.0056 16.6 2.4 3.2 3 0 0 3 3 3 1 Chitin recognition protein WD40 PF00400.27 KFY02146.1 - 1.8e-72 236.8 18.6 3.2e-11 42.6 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat WSC PF01822.14 KFY02146.1 - 6.7e-45 150.9 39.8 4.4e-17 61.7 6.2 3.7 3 0 0 3 3 3 3 WSC domain Nup160 PF11715.3 KFY02146.1 - 1e-05 23.8 6.1 0.0039 15.3 0.6 4.1 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFY02146.1 - 0.0001 21.2 0.7 0.4 9.3 0.1 3.2 2 1 1 4 4 4 2 Nup133 N terminal like LysM PF01476.15 KFY02146.1 - 0.00051 19.8 0.6 0.023 14.5 0.3 2.6 2 0 0 2 2 2 1 LysM domain Meckelin PF09773.4 KFY02147.1 - 0.013 13.3 0.1 0.014 13.1 0.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Herpes_gE PF02480.11 KFY02147.1 - 0.054 11.7 0.4 0.054 11.7 0.3 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PspB PF06667.7 KFY02147.1 - 0.07 13.0 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Phage shock protein B PMP1_2 PF08114.6 KFY02147.1 - 0.09 12.2 3.4 0.16 11.5 2.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family SCIMP PF15050.1 KFY02147.1 - 0.22 11.4 2.7 0.32 10.9 1.8 1.2 1 0 0 1 1 1 0 SCIMP protein Fungal_trans PF04082.13 KFY02148.1 - 2.8e-11 42.7 1.0 4.6e-11 42.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFY02148.1 - 0.00018 21.6 1.7 0.00043 20.4 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY02148.1 - 0.00092 19.3 2.1 0.0037 17.4 1.4 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger K-box PF01486.12 KFY02148.1 - 0.037 13.8 0.2 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 K-box region Sugar_tr PF00083.19 KFY02149.1 - 2e-83 280.4 35.5 2.4e-83 280.2 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02149.1 - 2.6e-32 111.9 32.6 2.6e-32 111.9 22.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFY02149.1 - 1e-05 24.1 4.5 1e-05 24.1 3.1 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFY02149.1 - 7.6e-05 21.0 2.9 7.6e-05 21.0 2.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TM_GPCR_Srw PF10324.4 KFY02149.1 - 0.0076 15.4 1.4 0.0076 15.4 1.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3413 PF11893.3 KFY02149.1 - 0.018 13.9 0.2 0.018 13.9 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) PalH PF08733.5 KFY02149.1 - 3.7 6.3 8.1 6 5.5 5.6 1.2 1 0 0 1 1 1 0 PalH/RIM21 Glyco_hydro_2_N PF02837.13 KFY02150.1 - 3.1e-10 39.8 0.0 6.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFY02150.1 - 4.8e-07 30.1 0.0 1.4e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFY02150.1 - 5.9e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PKD PF00801.15 KFY02150.1 - 0.11 12.3 0.3 2.2 8.0 0.0 2.6 1 1 1 2 2 2 0 PKD domain Lipase_GDSL_2 PF13472.1 KFY02151.1 - 4.1e-14 53.1 4.1 5.3e-14 52.7 2.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY02151.1 - 7e-08 32.5 2.5 9.8e-08 32.1 1.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GMC_oxred_N PF00732.14 KFY02154.1 - 8.8e-65 218.7 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY02154.1 - 8.5e-31 107.1 0.0 1.5e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KFY02154.1 - 2.7e-05 23.2 0.1 6.2e-05 22.0 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFY02154.1 - 8.5e-05 21.5 0.6 0.12 11.1 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KFY02154.1 - 0.00016 21.6 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY02154.1 - 0.00036 19.5 0.8 0.084 11.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFY02154.1 - 0.039 12.5 0.1 0.057 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KFY02154.1 - 0.045 13.7 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY02154.1 - 0.1 11.6 0.2 0.28 10.2 0.1 1.7 1 0 0 1 1 1 0 Thi4 family Vint PF14623.1 KFY02155.1 - 4.2e-41 140.1 0.0 7e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KFY02155.1 - 2.6e-23 81.9 0.0 5.3e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.23 KFY02155.1 - 1.6e-20 73.5 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFY02155.1 - 1.7e-20 73.8 0.0 5.1e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFY02155.1 - 2.1e-13 50.2 0.0 6.1e-11 42.2 0.0 2.8 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFY02155.1 - 0.017 14.2 0.0 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KFY02155.1 - 0.13 12.0 0.0 1.1 8.9 0.0 2.1 1 1 0 1 1 1 0 vWA found in TerF C terminus FA_desaturase PF00487.19 KFY02156.1 - 1.4e-14 54.2 17.6 1.6e-14 53.9 11.7 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Pro_CA PF00484.14 KFY02159.1 - 1.3e-47 161.5 0.1 1.7e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.15 KFY02159.1 - 0.025 13.5 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily TauD PF02668.11 KFY02160.1 - 9.8e-49 166.3 0.4 1.3e-48 165.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF427 PF04248.7 KFY02161.1 - 5.8e-27 93.2 1.0 9.5e-24 82.8 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) HTH_17 PF12728.2 KFY02161.1 - 0.0043 17.2 0.0 0.021 15.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain TRP PF06011.7 KFY02162.1 - 2.4e-150 500.9 25.0 5.6e-150 499.7 17.3 1.6 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFY02162.1 - 5.1e-38 130.2 0.7 9.8e-38 129.3 0.5 1.5 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.11 KFY02162.1 - 2.4e-21 75.8 36.9 1.7e-19 69.7 18.7 4.8 3 2 1 4 4 4 2 Major Facilitator Superfamily gpUL132 PF11359.3 KFY02162.1 - 0.077 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 DUF843 PF05814.6 KFY02162.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) SMI1_KNR4 PF09346.5 KFY02163.1 - 0.00063 19.7 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) DUF4407 PF14362.1 KFY02164.1 - 1.3 7.8 5.7 0.068 12.1 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nucleoside_tran PF01733.13 KFY02165.1 - 5.5e-25 88.1 4.2 6.4e-25 87.9 2.9 1.0 1 0 0 1 1 1 1 Nucleoside transporter cobW PF02492.14 KFY02166.1 - 2.4e-45 154.1 2.6 1.2e-33 116.0 0.0 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain A_deaminase PF00962.17 KFY02166.1 - 8.3e-35 120.2 0.0 1.3e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase CobW_C PF07683.9 KFY02166.1 - 1.4e-20 72.8 0.1 5.1e-15 54.9 0.0 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 KFY02166.1 - 0.023 14.8 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFY02166.1 - 0.025 14.3 0.3 0.32 10.7 0.0 3.2 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 KFY02166.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.9 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KFY02166.1 - 0.2 11.2 0.2 0.41 10.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PA14_2 PF10528.4 KFY02167.1 - 3.7e-21 75.2 0.2 5.5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KFY02167.1 - 1.1e-08 34.8 0.1 1.6e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 PA14 domain Stig1 PF04885.8 KFY02167.1 - 0.0073 16.5 23.5 0.011 15.8 16.3 1.2 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 GMC_oxred_N PF00732.14 KFY02168.1 - 5.5e-29 101.2 0.0 1.6e-25 89.8 0.0 2.7 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY02168.1 - 6.4e-28 97.8 0.0 1.2e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KFY02168.1 - 9.9e-05 22.2 2.0 0.00029 20.8 1.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KFY02168.1 - 0.0027 17.1 0.1 0.0061 16.0 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KFY02168.1 - 0.0065 15.3 2.0 0.011 14.6 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY02168.1 - 0.0087 15.9 0.1 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY02168.1 - 0.017 14.0 1.6 0.12 11.2 1.3 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFY02168.1 - 0.035 12.5 0.4 0.052 12.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KFY02168.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PhoPQ_related PF10142.4 KFY02168.1 - 0.25 9.7 0.0 0.43 9.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein APH PF01636.18 KFY02169.1 - 6e-12 45.8 0.1 8.9e-11 41.9 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFY02169.1 - 0.0033 16.1 0.0 0.28 9.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 KFY02169.1 - 0.11 11.4 0.0 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Lectin_leg-like PF03388.8 KFY02171.1 - 2e-66 223.4 0.0 2.9e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KFY02171.1 - 0.0021 17.4 0.0 0.5 9.6 0.0 2.7 3 0 0 3 3 3 2 Legume lectin domain ATG27 PF09451.5 KFY02171.1 - 0.0048 16.1 0.1 0.0057 15.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 zf-Tim10_DDP PF02953.10 KFY02172.1 - 1.2e-23 82.1 2.6 1.4e-23 81.9 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_4 PF08386.5 KFY02172.1 - 0.07 13.0 0.0 0.81 9.6 0.0 2.1 1 1 0 1 1 1 0 TAP-like protein DDE_1 PF03184.14 KFY02175.1 - 3.5e-55 186.4 0.0 5.9e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KFY02175.1 - 1.3e-10 41.1 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFY02175.1 - 0.00027 20.6 0.0 0.00096 18.9 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 KFY02175.1 - 0.0011 18.4 0.2 0.0033 16.9 0.1 1.9 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_37 PF13744.1 KFY02175.1 - 0.031 14.0 0.4 0.085 12.6 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Catalase-rel PF06628.7 KFY02176.1 - 3.5e-13 49.2 0.0 6.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KFY02176.1 - 2.7e-08 33.3 0.0 4.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFY02176.1 - 0.00079 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DUF3435 PF11917.3 KFY02177.1 - 1.8e-15 56.6 0.0 3.5e-15 55.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Chromo PF00385.19 KFY02177.1 - 9.1e-11 41.2 4.2 2.2e-06 27.2 0.7 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Phage_integrase PF00589.17 KFY02177.1 - 0.0039 16.8 0.0 0.16 11.6 0.0 2.8 3 0 0 3 3 3 1 Phage integrase family DUF3435 PF11917.3 KFY02188.1 - 6.8e-28 97.5 1.2 9e-28 97.1 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-met PF12874.2 KFY02188.1 - 0.04 14.1 0.4 0.14 12.4 0.3 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFY02188.1 - 0.55 10.6 7.3 2.2 8.7 1.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY02188.1 - 7 7.2 6.1 28 5.3 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Filament PF00038.16 KFY02189.1 - 0.0055 16.2 13.7 0.0055 16.2 9.5 3.0 2 1 1 3 3 3 1 Intermediate filament protein MtrG PF04210.8 KFY02189.1 - 2.9 7.6 7.6 0.24 11.1 0.2 2.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G IncA PF04156.9 KFY02189.1 - 4.2 6.9 30.8 0.5 9.9 3.6 3.8 2 1 2 4 4 4 0 IncA protein APH PF01636.18 KFY02190.1 - 8.2e-11 42.0 0.0 4.9e-10 39.5 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Transpep_BrtH PF14399.1 KFY02191.1 - 0.11 11.7 0.5 0.23 10.7 0.2 1.6 1 1 0 1 1 1 0 NlpC/p60-like transpeptidase SAM_1 PF00536.25 KFY02192.1 - 7.5e-10 38.8 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFY02192.1 - 0.00027 20.7 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box PF00505.14 KFY02193.1 - 8.6e-11 41.9 0.1 1.5e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY02193.1 - 6.2e-10 39.3 0.2 1.2e-09 38.4 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KFY02193.1 - 6.2e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFY02193.1 - 2.5e-08 33.6 0.0 6.9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ub-Mut7C PF14451.1 KFY02199.1 - 0.039 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin DAO PF01266.19 KFY02200.1 - 0.033 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY02200.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFY02200.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Chromate_transp PF02417.10 KFY02201.1 - 8.9e-07 28.6 5.8 1.1e-06 28.2 4.0 1.1 1 0 0 1 1 1 1 Chromate transporter DUF4225 PF13988.1 KFY02201.1 - 0.022 14.2 0.0 0.12 11.7 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) His_Phos_1 PF00300.17 KFY02202.1 - 1.3e-18 67.5 0.0 1.6e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pyr_redox_3 PF13738.1 KFY02212.1 - 2e-19 70.4 0.0 3.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY02212.1 - 1e-08 33.8 0.1 2.4e-08 32.6 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY02212.1 - 2.5e-08 33.8 0.0 6e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFY02212.1 - 4.2e-08 32.4 0.0 4.8e-07 29.0 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) bZIP_1 PF00170.16 KFY02212.1 - 0.00029 20.7 8.8 0.0056 16.5 2.8 2.4 2 0 0 2 2 2 2 bZIP transcription factor NAD_binding_9 PF13454.1 KFY02212.1 - 0.00042 20.1 0.0 0.0057 16.4 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFY02212.1 - 0.0033 17.3 0.0 3.6 7.4 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY02212.1 - 0.0084 15.2 0.1 0.036 13.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFY02212.1 - 0.02 13.8 0.0 0.23 10.3 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY02212.1 - 0.033 13.0 0.0 0.067 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain bZIP_2 PF07716.10 KFY02212.1 - 1.2 8.9 9.9 7.4 6.4 0.9 2.6 2 0 0 2 2 2 0 Basic region leucine zipper FMN_red PF03358.10 KFY02223.1 - 5.3e-08 32.5 0.0 1e-07 31.6 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Taq-exonuc PF09281.5 KFY02223.1 - 0.022 14.8 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Taq polymerase, exonuclease Peptidase_M43 PF05572.8 KFY02283.1 - 1.1e-16 60.7 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.19 KFY02283.1 - 0.00089 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 KFY02283.1 - 0.0022 18.1 0.1 0.0052 16.8 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFY02283.1 - 0.0022 17.5 0.1 0.0043 16.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFY02283.1 - 0.016 15.1 2.0 0.025 14.4 0.7 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFY02283.1 - 0.41 11.1 1.7 1.7 9.2 0.0 2.8 3 1 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Sugar_tr PF00083.19 KFY02285.1 - 2.6e-81 273.5 23.9 2.9e-81 273.3 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02285.1 - 1.8e-20 72.9 30.2 1.8e-20 72.9 21.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY02285.1 - 6.4e-07 28.1 32.5 5.3e-05 21.7 2.0 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein Sulfatase PF00884.18 KFY02286.1 - 3.2e-67 226.9 0.1 4.2e-67 226.5 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFY02286.1 - 5.5e-10 39.0 5.2 3.7e-09 36.3 3.6 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFY02286.1 - 0.021 13.2 0.0 0.036 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RepL PF05732.6 KFY02286.1 - 0.073 12.2 0.3 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Romo1 PF10247.4 KFY02302.1 - 6.4e-27 93.5 13.0 8.4e-27 93.1 9.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 KFY02302.1 - 0.4 10.7 7.9 0.73 9.8 5.4 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 KFY02302.1 - 4 7.1 5.4 25 4.5 3.8 2.0 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 KFY02302.1 - 5.9 6.4 8.9 1.2 8.6 3.1 2.0 1 1 1 2 2 2 0 YMGG-like Gly-zipper DUF3435 PF11917.3 KFY02309.1 - 8.4e-06 24.7 0.7 3.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Med7 PF05983.6 KFY02309.1 - 0.081 12.6 1.1 0.62 9.8 0.2 2.1 2 0 0 2 2 2 0 MED7 protein NinE PF05322.6 KFY02309.1 - 0.88 9.3 4.9 7 6.4 0.1 3.5 3 0 0 3 3 3 0 NINE Protein TPR_10 PF13374.1 KFY02338.1 - 1.3e-124 403.0 13.5 7.3e-11 41.6 0.0 12.5 11 1 1 12 12 12 12 Tetratricopeptide repeat TPR_12 PF13424.1 KFY02338.1 - 1.4e-92 303.7 16.5 3.6e-15 55.6 0.0 9.9 2 2 6 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 KFY02338.1 - 1.3e-29 99.8 19.8 0.3 11.4 0.0 10.8 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_16 PF13432.1 KFY02338.1 - 1.2e-21 76.8 9.6 0.014 16.0 0.0 10.1 2 2 8 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 KFY02338.1 - 3.3e-20 70.2 30.3 0.22 11.4 0.0 11.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02338.1 - 1.8e-18 65.8 12.9 0.018 14.6 0.1 7.3 2 2 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 KFY02338.1 - 4.1e-17 60.9 23.7 0.016 14.7 0.1 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KFY02338.1 - 4.4e-16 58.9 23.4 0.2 12.0 0.0 10.7 3 2 7 10 10 10 5 Tetratricopeptide repeat TPR_4 PF07721.9 KFY02338.1 - 1.5e-15 55.9 10.8 0.4 11.2 0.0 10.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02338.1 - 5.7e-15 53.9 21.3 0.54 10.3 0.1 10.4 10 0 0 10 10 10 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KFY02338.1 - 5.6e-10 38.5 0.2 1.3e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_3 PF07720.7 KFY02338.1 - 2e-07 30.6 16.1 0.52 10.1 0.1 8.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFY02338.1 - 8.3e-06 25.2 19.7 0.31 10.9 0.1 10.0 11 0 0 11 11 11 2 Tetratricopeptide repeat NB-ARC PF00931.17 KFY02338.1 - 4.6e-05 22.4 0.2 0.00011 21.2 0.1 1.6 1 1 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KFY02338.1 - 4.7e-05 23.4 1.4 0.9 9.7 0.2 4.8 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 LRR_8 PF13855.1 KFY02338.1 - 1.2 8.9 9.2 2.8e+02 1.3 0.0 7.3 11 0 0 11 11 10 0 Leucine rich repeat TPR_14 PF13428.1 KFY02338.1 - 2.5 8.9 25.5 1.2e+02 3.7 0.2 9.3 5 3 5 10 10 10 0 Tetratricopeptide repeat FBA PF04300.8 KFY02338.1 - 2.7 7.9 5.2 24 4.8 0.2 3.3 2 1 1 3 3 3 0 F-box associated region CorA PF01544.13 KFY02339.1 - 2.2e-12 46.6 0.3 2.7e-12 46.3 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein V-SNARE_C PF12352.3 KFY02339.1 - 0.087 12.9 3.4 0.12 12.5 0.3 2.4 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Cation_efflux PF01545.16 KFY02342.1 - 1.7e-13 50.2 0.1 2.7e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Cation efflux family Fez1 PF06818.10 KFY02344.1 - 0.0013 18.7 0.2 65 3.4 0.0 4.1 4 0 0 4 4 4 0 Fez1 Chisel PF15355.1 KFY02344.1 - 0.012 15.6 11.4 1.4 8.9 0.9 3.3 1 1 2 3 3 3 0 Stretch-responsive small skeletal muscle X protein, Chisel Cornifin PF02389.10 KFY02344.1 - 0.02 14.6 8.2 0.073 12.8 5.7 1.9 1 1 0 1 1 1 0 Cornifin (SPRR) family DUF2862 PF11061.3 KFY02344.1 - 0.026 14.2 0.3 12 5.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2862) CheX PF13690.1 KFY02344.1 - 0.034 13.9 6.5 13 5.7 0.0 3.9 2 2 3 5 5 5 0 Chemotaxis phosphatase CheX DUF2277 PF10041.4 KFY02344.1 - 0.17 11.8 14.7 7.4 6.6 0.1 4.6 2 1 3 5 5 5 0 Uncharacterized conserved protein (DUF2277) BON PF04972.12 KFY02344.1 - 0.89 9.3 14.8 7.6 6.3 0.2 4.3 4 0 0 4 4 4 0 BON domain CLPTM1 PF05602.7 KFY02345.1 - 4.8e-160 533.0 0.0 5.8e-160 532.7 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.9 KFY02346.1 - 5.2e-31 107.2 0.0 7.3e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Vps55 PF04133.9 KFY02347.1 - 2.7e-46 156.2 5.1 3e-46 156.0 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 GtrA PF04138.9 KFY02347.1 - 0.079 12.9 2.7 0.13 12.2 1.9 1.3 1 1 0 1 1 1 0 GtrA-like protein Proteasome PF00227.21 KFY02348.1 - 7.8e-47 159.0 0.1 9.8e-47 158.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFY02348.1 - 4.4e-11 41.8 0.2 7.1e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chorismate_bind PF00425.13 KFY02349.1 - 8.9e-65 218.5 0.0 4.9e-36 124.3 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KFY02349.1 - 1.2e-21 77.1 0.0 8.6e-20 70.9 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KFY02349.1 - 2.5e-15 56.7 0.0 4.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KFY02349.1 - 0.0068 15.8 0.9 0.088 12.2 0.1 2.2 2 0 0 2 2 2 1 Peptidase C26 PagL PF09411.5 KFY02349.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) IP_trans PF02121.13 KFY02349.1 - 0.047 12.8 0.1 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein UAA PF08449.6 KFY02350.1 - 1.5e-12 47.0 19.5 1.9e-12 46.7 13.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFY02350.1 - 2.4e-08 33.7 8.3 2.4e-08 33.7 5.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFY02350.1 - 1.4e-05 25.0 27.7 0.00044 20.2 6.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Thioredoxin PF00085.15 KFY02351.1 - 2.1e-07 30.5 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KFY02351.1 - 1.2e-05 24.1 0.1 1.5e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin Mt_ATP-synt_B PF05405.9 KFY02351.1 - 0.061 12.7 0.2 0.098 12.1 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Thioredoxin_7 PF13899.1 KFY02351.1 - 0.13 12.2 0.4 0.94 9.5 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like ARD PF03079.9 KFY02352.1 - 1.3e-43 148.6 0.1 1.3e-43 148.6 0.1 1.8 2 0 0 2 2 2 1 ARD/ARD' family adh_short PF00106.20 KFY02352.1 - 7.9e-19 68.1 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY02352.1 - 1e-08 35.0 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.6 KFY02352.1 - 2.9e-08 33.1 0.0 6.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Epimerase PF01370.16 KFY02352.1 - 2.9e-06 26.9 0.0 9.5e-06 25.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AraC_binding PF02311.14 KFY02352.1 - 2e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short_C2 PF13561.1 KFY02352.1 - 0.00071 19.4 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cupin_1 PF00190.17 KFY02352.1 - 0.004 16.6 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Cupin NAD_binding_10 PF13460.1 KFY02352.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding GIDA PF01134.17 KFY02353.1 - 5.9e-160 532.4 0.0 8.6e-160 531.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KFY02353.1 - 9.2e-16 57.6 0.0 2.2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KFY02353.1 - 2.1e-08 34.2 0.1 4.5e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFY02353.1 - 2.1e-06 27.0 0.1 3.7e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFY02353.1 - 2.7e-05 23.2 0.3 0.068 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY02353.1 - 0.00047 19.1 1.2 0.00088 18.2 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KFY02353.1 - 0.0084 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KFY02353.1 - 0.014 13.8 1.7 0.081 11.3 0.3 2.4 2 0 0 2 2 2 0 HI0933-like protein Pet127 PF08634.5 KFY02354.1 - 9.5e-115 382.4 0.1 1.4e-114 381.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 STAT1_TAZ2bind PF12162.3 KFY02355.1 - 0.038 13.3 1.0 0.038 13.3 0.7 1.9 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Glyco_hydro_7 PF00840.15 KFY02356.1 - 2.2e-217 721.6 25.3 2.8e-217 721.2 17.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KFY02356.1 - 6.6e-13 48.0 12.5 6.6e-13 48.0 8.6 4.1 5 0 0 5 5 5 1 Fungal cellulose binding domain SLT PF01464.15 KFY02357.1 - 4.3e-07 29.4 0.0 1.2e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Transglycosylase SLT domain Bac_rhamnosid PF05592.6 KFY02358.1 - 2.1e-21 75.7 0.6 7e-12 44.3 0.1 3.0 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFY02358.1 - 0.00011 21.0 1.4 0.00018 20.3 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KFY02358.1 - 0.018 13.7 0.2 0.029 13.0 0.2 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KFY02358.1 - 0.041 12.5 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Trehalase LtrA PF06772.6 KFY02359.1 - 1.6e-18 66.7 20.2 2.3e-18 66.2 14.0 1.3 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Vpu PF00558.14 KFY02359.1 - 0.3 10.6 2.6 4.3 6.9 0.6 2.9 2 0 0 2 2 2 0 Vpu protein COX6C PF02937.10 KFY02360.1 - 0.16 11.8 0.2 0.36 10.7 0.2 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DKCLD PF08068.7 KFY02361.1 - 2.7e-29 100.8 0.1 1.6e-28 98.4 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KFY02361.1 - 3.1e-24 85.8 0.3 2.9e-21 76.1 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KFY02361.1 - 1.7e-21 75.7 1.2 3.3e-21 74.7 0.9 1.5 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 KFY02361.1 - 0.086 12.4 26.2 0.14 11.7 18.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 KFY02361.1 - 1.3 8.1 12.2 2.1 7.4 8.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 KFY02361.1 - 9.5 5.8 20.2 24 4.5 14.0 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NDT80_PhoG PF05224.7 KFY02365.1 - 2.5e-42 144.9 0.0 3.4e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Myb_DNA-binding PF00249.26 KFY02365.1 - 0.006 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TOH_N PF12549.3 KFY02376.1 - 0.46 10.1 3.4 12 5.5 0.1 2.5 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal Ub-Mut7C PF14451.1 KFY02381.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Mut7-C ubiquitin Pkinase PF00069.20 KFY02382.1 - 4e-14 52.4 0.0 8.4e-14 51.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02382.1 - 0.034 13.2 0.0 0.071 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF3723 PF12520.3 KFY02388.1 - 4.8e-92 309.0 6.0 8.4e-92 308.2 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3723) BTB PF00651.26 KFY02388.1 - 1.7e-13 50.5 0.0 3.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Na_H_Exchanger PF00999.16 KFY02390.1 - 9.7e-29 100.0 42.0 4.5e-23 81.3 17.7 3.3 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family PetM PF08041.6 KFY02390.1 - 0.1 12.1 4.1 0.32 10.5 0.1 3.0 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 BCHF PF07284.6 KFY02390.1 - 4.3 7.1 6.6 29 4.4 0.1 3.4 3 0 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) Rgp1 PF08737.5 KFY02392.1 - 0.0049 16.0 0.0 0.69 8.9 0.0 2.1 2 0 0 2 2 2 2 Rgp1 bZIP_1 PF00170.16 KFY02394.1 - 0.11 12.4 0.8 0.17 11.8 0.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Antimicrobial_9 PF08104.6 KFY02394.1 - 0.21 11.3 0.7 24 4.8 0.0 2.5 2 0 0 2 2 2 0 Ponericin L family Dynamin_M PF01031.15 KFY02395.1 - 2.7e-31 108.4 0.3 3e-29 101.7 0.2 2.2 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KFY02395.1 - 1.8e-25 89.7 0.0 5e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KFY02395.1 - 8.6e-05 22.4 0.0 0.0079 16.1 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFY02395.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KFY02395.1 - 0.0093 15.2 0.0 3.1 7.0 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B OTT_1508_deam PF14441.1 KFY02396.1 - 9.5e-07 28.7 0.0 1.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase TAFH PF07531.9 KFY02396.1 - 0.057 13.0 0.1 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 NHR1 homology to TAF Ribonucleas_3_3 PF14622.1 KFY02397.1 - 9.5e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFY02397.1 - 6.1e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Dynamin_N PF00350.18 KFY02398.1 - 9.4e-26 90.6 0.0 2.4e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFY02398.1 - 7.3e-16 57.8 3.2 5e-15 55.0 0.0 2.9 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 KFY02398.1 - 0.0015 18.4 0.1 0.009 15.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KFY02398.1 - 0.0071 16.2 0.1 0.062 13.2 0.0 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain Miro PF08477.8 KFY02398.1 - 0.021 15.3 0.0 0.065 13.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein TAF PF02969.12 KFY02398.1 - 0.078 12.9 0.8 5.5 7.0 0.1 2.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) UDPGT PF00201.13 KFY02398.1 - 0.12 10.8 1.9 0.18 10.3 1.3 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Tropomyosin PF00261.15 KFY02399.1 - 0.11 11.6 18.2 0.062 12.3 8.6 2.1 2 0 0 2 2 2 0 Tropomyosin HSP70 PF00012.15 KFY02400.1 - 2.5e-08 32.3 0.1 1.1e-05 23.5 0.1 2.6 2 1 0 2 2 2 2 Hsp70 protein B9-C2 PF07162.6 KFY02400.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein DUF2875 PF11394.3 KFY02400.1 - 0.12 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) MULE PF10551.4 KFY02402.1 - 0.0084 16.2 0.1 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF3779 PF12621.3 KFY02403.1 - 3.7e-13 49.1 0.0 5.2e-13 48.7 0.0 1.3 1 1 0 1 1 1 1 Phosphate metabolism protein Ank_2 PF12796.2 KFY02415.1 - 1.7e-100 329.5 29.1 3e-17 62.7 0.0 10.2 4 2 8 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02415.1 - 5.6e-79 256.2 56.0 8.6e-07 28.4 0.1 21.4 21 0 0 21 21 21 17 Ankyrin repeat Ank_4 PF13637.1 KFY02415.1 - 1.5e-62 206.9 23.9 3.1e-07 30.7 0.0 17.1 4 3 14 19 19 18 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02415.1 - 2.7e-51 166.3 30.6 0.00017 21.5 0.0 19.6 20 0 0 20 20 19 13 Ankyrin repeat Ank_5 PF13857.1 KFY02415.1 - 1.8e-39 132.8 34.4 5.1e-06 26.5 0.1 14.9 9 3 6 16 16 15 11 Ankyrin repeats (many copies) NACHT PF05729.7 KFY02415.1 - 9e-12 44.9 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFY02415.1 - 4.9e-05 23.4 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY02415.1 - 0.00044 20.2 0.0 0.0016 18.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KFY02415.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KFY02415.1 - 0.013 14.3 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Shigella_OspC PF06128.6 KFY02415.1 - 0.053 13.0 2.5 71 2.7 0.0 6.0 7 1 1 8 8 8 0 Shigella flexneri OspC protein Arch_ATPase PF01637.13 KFY02415.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 KFY02415.1 - 0.063 13.1 0.0 0.3 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KFY02415.1 - 0.21 10.5 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KFY02415.1 - 0.44 9.4 1.9 13 4.6 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain Sugar_tr PF00083.19 KFY02417.1 - 4.3e-75 253.0 25.3 5.1e-75 252.7 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02417.1 - 8.4e-23 80.6 44.9 4.9e-20 71.5 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YMF19 PF02326.10 KFY02417.1 - 0.019 15.5 1.3 0.91 10.1 0.0 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 Pam17 PF08566.5 KFY02417.1 - 0.06 13.0 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 PalH PF08733.5 KFY02417.1 - 0.74 8.5 14.9 0.11 11.2 6.4 2.0 1 1 1 2 2 2 0 PalH/RIM21 Glyco_hydro_1 PF00232.13 KFY02418.1 - 3.7e-152 506.6 0.7 4.6e-152 506.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans PF04082.13 KFY02419.1 - 5.5e-15 54.9 0.3 1.4e-14 53.6 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02419.1 - 2.8e-11 43.1 4.8 4.9e-11 42.3 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.13 KFY02420.1 - 5.3e-27 94.5 0.0 8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFY02420.1 - 0.00017 21.3 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 KFY02421.1 - 5.6e-08 31.9 0.0 7.5e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 KFY02422.1 - 1.8e-18 67.2 0.0 2.8e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY02422.1 - 4.9e-10 39.3 0.0 8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02422.1 - 2.5e-05 23.9 0.0 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFY02423.1 - 5.6e-24 85.2 1.1 6.7e-24 85.0 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY02423.1 - 8.5e-11 41.8 0.0 2e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02423.1 - 1.7e-09 37.5 0.3 2.7e-08 33.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFY02423.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase CAML PF14963.1 KFY02424.1 - 1.3 8.3 9.4 2.7 7.2 6.5 1.6 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ank_2 PF12796.2 KFY02425.1 - 4.1e-128 418.0 14.4 1.4e-20 73.3 0.2 10.6 4 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02425.1 - 9.6e-124 397.5 28.2 5.4e-09 35.4 0.0 20.5 20 1 0 20 20 20 18 Ankyrin repeat Ank_4 PF13637.1 KFY02425.1 - 2.9e-106 346.1 24.4 4.2e-13 49.4 0.1 15.5 6 4 9 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02425.1 - 2.2e-84 268.8 13.9 4.3e-05 23.3 0.0 20.0 20 0 0 20 20 20 17 Ankyrin repeat Ank_5 PF13857.1 KFY02425.1 - 6.3e-79 258.2 34.6 1.4e-12 47.4 0.3 12.4 6 3 6 13 13 13 13 Ankyrin repeats (many copies) AAA_16 PF13191.1 KFY02425.1 - 0.00084 19.3 0.7 0.0092 15.9 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KFY02425.1 - 0.0053 16.9 0.0 0.021 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Nbs1_C PF08599.5 KFY02427.1 - 0.093 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 YwhD PF08741.5 KFY02427.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 YwhD family Pkinase PF00069.20 KFY02428.1 - 1.5e-11 43.9 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02428.1 - 1.9e-06 27.1 0.0 2.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY02428.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFY02428.1 - 0.07 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Zip PF02535.17 KFY02452.1 - 1.1e-13 50.9 0.0 1.2e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FAM70 PF14967.1 KFY02459.1 - 6.2 5.9 6.0 9 5.3 4.1 1.2 1 0 0 1 1 1 0 FAM70 protein IncA PF04156.9 KFY02460.1 - 0.0022 17.6 4.1 0.0032 17.0 2.8 1.2 1 0 0 1 1 1 1 IncA protein FadA PF09403.5 KFY02460.1 - 0.039 13.9 2.4 0.083 12.9 1.7 1.6 1 0 0 1 1 1 0 Adhesion protein FadA DUF3552 PF12072.3 KFY02460.1 - 0.28 10.3 6.1 0.42 9.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SlyX PF04102.7 KFY02460.1 - 2.5 8.5 5.0 20 5.6 2.5 2.7 1 1 1 2 2 2 0 SlyX Pox_A_type_inc PF04508.7 KFY02460.1 - 6.5 6.8 11.0 10 6.1 0.7 4.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat F-box PF00646.28 KFY02461.1 - 0.11 12.1 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain Ada3 PF10198.4 KFY02466.1 - 0.14 11.9 7.7 0.89 9.3 1.3 3.2 2 1 1 3 3 3 0 Histone acetyltransferases subunit 3 PPO1_KFDV PF12143.3 KFY02466.1 - 0.23 11.3 5.5 1.1 9.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF_B2219) DUF1409 PF07197.7 KFY02466.1 - 0.44 10.6 7.9 3.3 7.8 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) Peptidase_C6 PF00851.13 KFY02466.1 - 0.52 8.8 7.5 0.69 8.4 5.2 1.1 1 0 0 1 1 1 0 Helper component proteinase DUF1307 PF06998.6 KFY02466.1 - 1.1 9.3 5.8 3 7.8 1.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1307) TMF_TATA_bd PF12325.3 KFY02466.1 - 1.4 8.6 12.6 0.49 10.1 6.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3723 PF12520.3 KFY02467.1 - 1.2e-90 304.4 0.3 3.7e-90 302.8 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) rve_2 PF13333.1 KFY02467.1 - 0.14 12.2 2.4 7.6 6.6 0.1 3.3 3 0 0 3 3 3 0 Integrase core domain DUF3723 PF12520.3 KFY02484.1 - 6.5e-61 206.3 1.0 4.5e-30 104.6 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3723) HHH_5 PF14520.1 KFY02484.1 - 0.014 15.5 0.1 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH PF00633.18 KFY02484.1 - 0.12 12.1 0.1 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ank_2 PF12796.2 KFY02487.1 - 7.7e-44 147.9 2.3 3.6e-16 59.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02487.1 - 1.2e-38 129.0 0.7 1.2e-06 27.9 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFY02487.1 - 8.1e-28 95.8 3.1 7.3e-06 26.0 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02487.1 - 1.1e-25 87.0 0.1 0.0047 17.0 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFY02487.1 - 5.1e-25 87.3 1.7 1.5e-09 38.0 0.0 4.0 2 1 1 4 4 4 3 Ankyrin repeats (many copies) zf-RING_2 PF13639.1 KFY02487.1 - 6.5e-06 25.8 6.5 1.1e-05 25.0 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFY02487.1 - 0.004 16.8 3.0 0.0063 16.1 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1101 PF06503.6 KFY02487.1 - 0.011 14.5 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) IncA PF04156.9 KFY02497.1 - 0.0036 16.9 0.0 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 IncA protein RE_Eco47II PF09553.5 KFY02497.1 - 0.039 13.0 0.2 0.046 12.8 0.1 1.1 1 0 0 1 1 1 0 Eco47II restriction endonuclease DUF2222 PF09984.4 KFY02497.1 - 0.094 12.1 0.4 0.15 11.4 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) MFS_1 PF07690.11 KFY02503.1 - 6e-19 67.9 43.8 1.7e-10 40.1 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Steroid_dh PF02544.11 KFY02503.1 - 0.0055 16.4 0.1 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Methyltransf_31 PF13847.1 KFY02504.1 - 6.4e-16 58.2 0.0 1.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY02504.1 - 3.6e-14 53.0 0.0 8.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY02504.1 - 1.6e-07 30.7 0.0 3.2e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFY02504.1 - 1e-06 29.0 0.1 4.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY02504.1 - 8.6e-06 26.1 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY02504.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02504.1 - 3.8e-05 24.2 0.0 0.0001 22.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFY02504.1 - 0.0006 19.5 0.0 0.00086 18.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KFY02504.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF904 PF06005.7 KFY02506.1 - 0.0085 16.3 0.7 0.016 15.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Laminin_I PF06008.9 KFY02506.1 - 0.012 14.9 2.1 0.019 14.3 1.5 1.2 1 0 0 1 1 1 0 Laminin Domain I SlyX PF04102.7 KFY02506.1 - 0.019 15.2 1.1 0.037 14.3 0.7 1.4 1 0 0 1 1 1 0 SlyX PspA_IM30 PF04012.7 KFY02506.1 - 0.021 14.1 2.8 0.032 13.5 2.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.6 KFY02506.1 - 0.024 13.3 1.3 0.033 12.8 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.1 KFY02506.1 - 0.024 15.0 4.7 0.043 14.2 3.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.7 KFY02506.1 - 0.026 14.2 2.4 0.04 13.6 1.7 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 KFY02506.1 - 0.05 13.5 7.9 0.088 12.7 5.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor HR1 PF02185.11 KFY02506.1 - 0.073 12.8 3.4 0.13 11.9 2.4 1.4 1 0 0 1 1 1 0 Hr1 repeat bZIP_2 PF07716.10 KFY02506.1 - 0.091 12.5 10.2 0.15 11.8 7.1 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Bap31 PF05529.7 KFY02506.1 - 0.18 11.2 1.5 0.28 10.6 1.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF812 PF05667.6 KFY02506.1 - 0.19 10.2 4.8 0.24 9.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 KFY02506.1 - 0.22 9.3 1.3 0.29 8.9 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 KFY02506.1 - 0.4 10.7 5.8 0.66 10.0 4.0 1.3 1 0 0 1 1 1 0 DivIVA protein IncA PF04156.9 KFY02506.1 - 0.56 9.7 4.1 0.84 9.2 2.9 1.2 1 0 0 1 1 1 0 IncA protein RRF PF01765.14 KFY02506.1 - 2.4 7.6 5.8 3.6 7.0 4.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor NAD_binding_6 PF08030.7 KFY02510.1 - 2.5e-17 63.2 0.0 4.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFY02510.1 - 3.9e-17 62.0 0.0 8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFY02510.1 - 1.3e-13 51.0 5.0 3e-13 49.9 3.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.1 KFY02510.1 - 0.00082 19.4 0.7 0.0022 18.0 0.5 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFY02510.1 - 0.0015 17.6 1.8 0.0035 16.5 1.2 1.6 1 0 0 1 1 1 1 EF hand FAD_binding_6 PF00970.19 KFY02510.1 - 0.015 15.4 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_5 PF13202.1 KFY02510.1 - 0.017 14.4 0.5 0.036 13.4 0.3 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KFY02510.1 - 0.056 13.3 0.8 0.2 11.6 0.5 1.9 1 0 0 1 1 1 0 EF-hand domain DZR PF12773.2 KFY02511.1 - 0.0031 17.2 4.2 0.005 16.6 2.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KFY02511.1 - 0.0061 15.7 11.1 0.01 15.0 7.6 1.5 1 1 0 1 1 1 1 zinc-ribbon domain Ribonuc_red_2_N PF08471.5 KFY02511.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 1 1 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase zinc_ribbon_2 PF13240.1 KFY02511.1 - 0.33 10.5 11.4 0.62 9.6 7.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain MARVEL PF01284.18 KFY02512.1 - 1e-09 38.3 14.4 1.6e-09 37.7 10.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain DZR PF12773.2 KFY02512.1 - 0.00061 19.5 1.8 0.001 18.8 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFY02512.1 - 0.00088 18.6 2.8 0.0025 17.2 1.9 1.8 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFY02512.1 - 0.0041 16.2 2.6 0.007 15.5 1.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain ABC2_membrane_5 PF13346.1 KFY02512.1 - 0.14 11.3 6.6 0.043 13.0 2.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4149 PF13664.1 KFY02512.1 - 0.33 11.0 6.5 1.2 9.2 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) zf-DHHC PF01529.15 KFY02512.1 - 0.56 9.5 2.5 5.5 6.3 0.1 2.5 1 1 0 2 2 2 0 DHHC palmitoyltransferase Glyco_hydro_31 PF01055.21 KFY02513.1 - 1.7e-111 373.2 0.0 2.1e-111 372.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFY02513.1 - 1.4e-17 63.3 0.2 3.1e-16 58.9 0.0 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like TRAP_alpha PF03896.11 KFY02514.1 - 1.5e-07 30.6 1.5 3e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit F-box PF00646.28 KFY02515.1 - 0.46 10.2 4.6 0.18 11.5 0.3 2.5 3 0 0 3 3 3 0 F-box domain Prominin PF05478.6 KFY02516.1 - 0.00024 18.8 0.4 0.00024 18.8 0.3 1.4 2 0 0 2 2 2 1 Prominin DUF2570 PF10828.3 KFY02516.1 - 0.0055 16.2 3.4 0.015 14.9 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) Prefoldin_2 PF01920.15 KFY02516.1 - 0.0083 15.8 0.8 0.018 14.8 0.6 1.5 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 KFY02516.1 - 0.019 14.6 1.6 0.06 13.0 1.1 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PilO PF04350.8 KFY02516.1 - 0.026 14.3 0.5 0.046 13.5 0.3 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO Transcrip_act PF04949.8 KFY02516.1 - 0.036 13.6 0.1 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator Lipoprotein_20 PF13942.1 KFY02516.1 - 0.052 13.0 0.5 0.088 12.3 0.4 1.3 1 0 0 1 1 1 0 YfhG lipoprotein DUF948 PF06103.6 KFY02516.1 - 1 9.2 5.5 0.64 9.9 1.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMEM171 PF15471.1 KFY02519.1 - 0.12 11.1 2.4 0.2 10.3 1.7 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 ELO PF01151.13 KFY02527.1 - 1e-08 34.7 0.5 1e-08 34.7 0.3 1.9 1 1 1 2 2 2 1 GNS1/SUR4 family Ubie_methyltran PF01209.13 KFY02528.1 - 3e-09 36.3 0.0 5.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFY02528.1 - 5.7e-09 36.3 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY02528.1 - 9.8e-07 28.6 0.0 2.1e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY02528.1 - 5.6e-06 26.6 0.0 9.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY02528.1 - 0.00034 20.6 0.1 0.00077 19.4 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY02528.1 - 0.00039 20.0 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02528.1 - 0.0014 19.1 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY02528.1 - 0.014 15.8 0.0 0.034 14.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UPF0182 PF03699.8 KFY02544.1 - 0.14 10.0 0.5 0.18 9.7 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Retrotrans_gag PF03732.12 KFY02545.1 - 0.016 15.2 2.6 0.021 14.8 0.1 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein bZIP_2 PF07716.10 KFY02545.1 - 0.037 13.8 2.0 0.037 13.8 1.4 3.1 3 1 0 3 3 3 0 Basic region leucine zipper HALZ PF02183.13 KFY02545.1 - 0.47 10.2 8.9 0.1 12.3 1.1 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1003 PF06210.6 KFY02545.1 - 5.5 6.9 9.5 0.17 11.7 1.0 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1003) Ank_2 PF12796.2 KFY02547.1 - 2.4e-16 59.8 0.0 4.7e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02547.1 - 2.8e-15 55.2 0.0 0.0001 21.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KFY02547.1 - 1.9e-12 46.0 0.0 0.00046 20.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFY02547.1 - 1.3e-07 31.9 0.0 0.0014 19.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY02547.1 - 5.8e-06 26.3 0.1 0.032 14.5 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) F-box PF00646.28 KFY02547.1 - 0.057 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 F-box domain HC2 PF07382.6 KFY02548.1 - 3.6e-06 26.9 25.0 3.6e-06 26.9 17.3 2.2 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 CENP-T PF15511.1 KFY02548.1 - 2.7 7.1 40.7 1.1 8.4 19.9 2.3 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Cu-oxidase_3 PF07732.10 KFY02549.1 - 1.2e-19 70.1 0.1 1.7e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 KFY02549.1 - 0.00066 19.6 0.0 0.0015 18.4 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFY02549.1 - 0.048 13.1 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Multicopper oxidase adh_short PF00106.20 KFY02579.1 - 1.3e-23 83.7 1.2 5.7e-23 81.6 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RTA1 PF04479.8 KFY02579.1 - 1.7e-22 79.9 1.1 1.1e-19 70.7 0.3 2.4 1 1 1 2 2 2 2 RTA1 like protein adh_short_C2 PF13561.1 KFY02579.1 - 8e-09 35.6 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 KFY02579.1 - 7.3e-08 31.4 4.3 3.9e-07 29.0 0.1 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain KR PF08659.5 KFY02579.1 - 4.7e-07 29.6 0.2 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFY02579.1 - 0.0005 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY02579.1 - 0.0044 17.0 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KFY02579.1 - 0.0093 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF3112 PF11309.3 KFY02580.1 - 5 6.9 10.0 1 9.1 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Cu-oxidase_2 PF07731.9 KFY02596.1 - 1.6e-40 137.7 0.7 2.5e-36 124.1 0.3 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFY02596.1 - 1.7e-19 69.7 0.6 1.1e-18 67.0 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KFY02596.1 - 7.8e-18 64.8 0.0 5.1e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase PEP_mutase PF13714.1 KFY02597.1 - 2.1e-45 154.8 0.2 3.2e-45 154.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFY02597.1 - 3.9e-23 81.4 0.3 5.8e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family HMA PF00403.21 KFY02598.1 - 3.4e-13 49.5 2.3 4e-13 49.3 1.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Flavi_glycoprot PF00869.15 KFY02598.1 - 0.061 12.2 0.2 0.062 12.2 0.1 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains E7 PF00527.13 KFY02598.1 - 0.12 12.5 0.1 0.2 11.8 0.0 1.5 1 1 1 2 2 2 0 E7 protein, Early protein RseC_MucC PF04246.7 KFY02598.1 - 0.12 11.8 0.1 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC E1-E2_ATPase PF00122.15 KFY02599.1 - 7.3e-44 149.5 0.1 5.6e-43 146.6 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFY02599.1 - 2.5e-41 142.4 0.1 4.6e-41 141.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFY02599.1 - 4.2e-31 106.8 0.5 2e-12 47.0 0.4 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KFY02599.1 - 3.9e-17 63.0 0.0 8.7e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY02599.1 - 6.2e-05 22.7 0.4 0.0019 17.8 0.2 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Bul1_C PF04426.7 KFY02610.1 - 0.012 14.8 0.1 0.028 13.6 0.1 1.6 1 0 0 1 1 1 0 Bul1 C terminus Sugar_tr PF00083.19 KFY02611.1 - 1.1e-41 142.8 24.7 1.6e-41 142.3 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02611.1 - 9.9e-20 70.5 51.9 9.2e-19 67.3 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY02611.1 - 0.00083 17.8 10.6 0.00083 17.8 7.3 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein HLH PF00010.21 KFY02612.1 - 2.4e-12 46.3 0.0 5.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YcbB PF08664.5 KFY02612.1 - 0.013 15.2 0.4 0.026 14.2 0.2 1.6 1 1 0 1 1 1 0 YcbB domain DTHCT PF08070.6 KFY02612.1 - 0.99 10.1 7.1 3.2 8.4 5.0 1.8 1 1 0 1 1 1 0 DTHCT (NUC029) region Tropomyosin_1 PF12718.2 KFY02621.1 - 0.0054 16.5 15.0 0.075 12.8 0.4 2.1 1 1 1 2 2 2 2 Tropomyosin like Phage_lysozyme PF00959.14 KFY02621.1 - 0.033 14.4 0.4 0.085 13.1 0.3 1.7 1 0 0 1 1 1 0 Phage lysozyme HR1 PF02185.11 KFY02621.1 - 4.9 6.9 11.7 4.4 7.1 1.0 3.2 4 0 0 4 4 4 0 Hr1 repeat Cyto_ox_2 PF02322.10 KFY02623.1 - 0.03 13.5 5.4 0.048 12.8 3.7 1.3 1 1 0 1 1 1 0 Cytochrome oxidase subunit II F-box PF00646.28 KFY02624.1 - 0.13 11.9 0.1 0.36 10.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain Glyco_hydro_18 PF00704.23 KFY02625.1 - 1.2e-82 278.1 1.4 1.5e-82 277.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3467 PF11950.3 KFY02626.1 - 0.022 14.7 0.0 0.083 12.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3467) HlyIII PF03006.15 KFY02654.1 - 5.9e-13 48.7 0.6 6.7e-13 48.5 0.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related HR1 PF02185.11 KFY02655.1 - 2.1 8.1 12.2 2.4 7.9 0.1 3.3 4 0 0 4 4 4 0 Hr1 repeat Nucleoplasmin PF03066.10 KFY02656.1 - 1.6 8.2 7.9 2.6 7.5 5.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Glyco_hydro_18 PF00704.23 KFY02659.1 - 2.2e-82 277.2 2.1 2.8e-82 276.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MscS_TM PF12794.2 KFY02663.1 - 3.3 6.2 4.6 4.1 5.9 3.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Macoilin PF09726.4 KFY02663.1 - 3.4 5.8 5.7 4.1 5.5 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Aminotran_3 PF00202.16 KFY02664.1 - 2.3e-63 214.1 0.0 2.5e-62 210.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III DUF3014 PF11219.3 KFY02664.1 - 0.022 14.6 0.1 0.085 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3014) AbiH PF14253.1 KFY02664.1 - 0.17 11.4 0.8 0.29 10.6 0.6 1.4 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Atg14 PF10186.4 KFY02664.1 - 3.9 6.3 10.5 6.8 5.5 7.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Methyltransf_23 PF13489.1 KFY02667.1 - 2.4e-16 59.8 0.1 4.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY02667.1 - 3e-08 33.3 0.0 1.6e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY02667.1 - 3.4e-08 33.8 0.0 1.2e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY02667.1 - 0.00072 19.9 0.0 0.0024 18.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02667.1 - 0.0012 19.3 0.2 0.022 15.3 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY02667.1 - 0.019 14.0 0.0 0.096 11.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 KFY02667.1 - 0.11 12.1 0.1 5.7 6.5 0.0 2.6 2 1 0 2 2 2 0 Hypothetical methyltransferase DUF1003 PF06210.6 KFY02667.1 - 0.32 10.9 1.7 0.67 9.9 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) DP PF08781.5 KFY02667.1 - 0.73 9.5 5.4 1.6 8.4 3.7 1.5 1 0 0 1 1 1 0 Transcription factor DP HSDR_N_2 PF13588.1 KFY02689.1 - 0.076 12.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Vfa1 PF08432.5 KFY02689.1 - 3.4 7.6 11.2 5.3 7.0 7.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2668 PF10873.3 KFY02691.1 - 0.28 11.3 3.0 0.63 10.1 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) InvH PF04741.7 KFY02691.1 - 0.35 10.7 3.3 0.34 10.7 0.8 2.0 1 1 1 2 2 2 0 InvH outer membrane lipoprotein Gly_transf_sug PF04488.10 KFY02714.1 - 9.2e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KFY02714.1 - 5e-07 29.1 0.0 7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KFY02714.1 - 0.026 13.0 0.1 0.18 10.2 0.0 2.0 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.10 KFY02715.1 - 1.4e-09 38.2 0.0 6.3e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KFY02715.1 - 7.4e-08 31.8 0.1 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KFY02715.1 - 0.011 14.3 0.0 0.26 9.7 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain ALO PF04030.9 KFY02716.1 - 3.2e-84 282.5 1.4 6.2e-84 281.6 1.0 1.5 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KFY02716.1 - 3.6e-27 94.5 0.0 6.3e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HC2 PF07382.6 KFY02716.1 - 6.3e-15 55.5 371.3 5.3e-06 26.4 62.6 6.2 2 1 5 7 7 7 6 Histone H1-like nucleoprotein HC2 DUF336 PF03928.9 KFY02717.1 - 1e-16 60.9 0.1 1.4e-16 60.5 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF336) DUF3625 PF12293.3 KFY02717.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3625) HEAT PF02985.17 KFY02718.1 - 1.2e-13 49.8 13.2 0.0005 19.9 0.1 9.5 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 KFY02718.1 - 2.7e-12 46.8 12.7 5.7e-05 23.3 0.1 7.1 2 1 5 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 KFY02718.1 - 2.2e-11 43.8 14.1 2.7e-06 27.7 0.0 8.5 6 3 4 10 10 10 3 HEAT-like repeat IBN_N PF03810.14 KFY02718.1 - 2.8e-08 33.5 1.2 1.5e-05 24.8 0.2 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 KFY02718.1 - 3.1e-08 33.2 2.3 0.01 15.2 0.0 5.8 5 2 2 7 7 7 3 CLASP N terminal Arm PF00514.18 KFY02718.1 - 0.00051 19.7 6.4 0.35 10.7 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KFY02718.1 - 0.0048 17.2 1.0 17 6.2 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HMGL-like PF00682.14 KFY02719.1 - 6.2e-63 212.6 0.0 9.3e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KFY02719.1 - 3e-24 85.3 0.0 5.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Zn_clus PF00172.13 KFY02720.1 - 0.0071 16.2 9.0 0.014 15.2 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cleaved_Adhesin PF07675.6 KFY02720.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Cleaved Adhesin Domain Rep_fac-A_C PF08646.5 KFY02720.1 - 0.93 9.1 3.4 1 9.0 1.1 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain LSM PF01423.17 KFY02721.1 - 1.9e-17 62.5 0.1 2.6e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KFY02721.1 - 0.0017 18.7 8.9 0.0031 17.9 6.2 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 TYW3 PF02676.9 KFY02722.1 - 5.4e-65 218.3 0.0 6.5e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 RRM_6 PF14259.1 KFY02723.1 - 0.00026 20.9 0.0 0.00054 19.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 KFY02724.1 - 1.5e-59 200.1 1.2 1.7e-59 200.0 0.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 KFY02725.1 - 7.4e-54 182.6 0.0 9.1e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFY02725.1 - 1.3e-16 60.8 0.0 4.5e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KFY02725.1 - 1.4e-10 40.3 1.1 2.7e-10 39.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family Coagulase PF08764.5 KFY02725.1 - 0.013 15.4 1.0 0.023 14.6 0.7 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Mto2_bdg PF12808.2 KFY02728.1 - 0.12 12.5 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2514 PF10721.4 KFY02731.1 - 0.025 14.3 4.3 0.04 13.6 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Atrophin-1 PF03154.10 KFY02731.1 - 0.64 8.0 4.6 0.88 7.6 3.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Helicase_C PF00271.26 KFY02744.1 - 4.1e-14 52.2 0.0 4.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_M13_N PF05649.8 KFY02759.1 - 0.093 11.7 0.2 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Peptidase family M13 Ferric_reduct PF01794.14 KFY02760.1 - 1.3e-10 41.4 8.0 5.6e-10 39.3 5.5 2.1 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFY02760.1 - 6.8e-08 32.3 0.0 1.8e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain DUF4112 PF13430.1 KFY02760.1 - 0.17 11.8 2.3 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Cation_ATPase_C PF00689.16 KFY02780.1 - 1.4e-12 47.5 0.3 1.9e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_efflux PF01545.16 KFY02782.1 - 1.4e-34 119.4 1.7 1.3e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Cation efflux family Abhydrolase_3 PF07859.8 KFY02796.1 - 8.2e-41 139.9 0.0 1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFY02796.1 - 1.9e-08 33.5 0.7 4.8e-08 32.1 0.5 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFY02796.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KFY02796.1 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KFY02796.1 - 0.02 14.1 0.1 1.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KFY02796.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFY02796.1 - 0.16 10.7 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase E1-E2_ATPase PF00122.15 KFY02797.1 - 7.6e-16 57.8 0.1 9.9e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY02797.1 - 3.4e-13 50.5 0.1 4.8e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY02797.1 - 0.0059 16.7 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sensor PF13796.1 KFY02797.1 - 0.074 12.6 5.5 0.1 12.1 3.8 1.2 1 0 0 1 1 1 0 Putative sensor Hydrolase PF00702.21 KFY02798.1 - 0.00016 22.1 0.0 0.00021 21.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY02798.1 - 0.00033 20.3 0.0 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2148 PF09918.4 KFY02798.1 - 0.027 14.2 0.1 0.053 13.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Fis1_TPR_N PF14852.1 KFY02798.1 - 0.034 13.4 0.1 0.065 12.5 0.1 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Cu-oxidase_3 PF07732.10 KFY02799.1 - 1.3e-09 37.8 5.2 3.6e-09 36.3 0.3 2.3 2 0 0 2 2 2 1 Multicopper oxidase Ctr PF04145.10 KFY02799.1 - 5e-05 23.3 0.8 8.7e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Cu-oxidase_2 PF07731.9 KFY02799.1 - 6.7e-05 22.4 4.0 0.0043 16.5 0.2 2.2 1 1 1 2 2 2 2 Multicopper oxidase Fra10Ac1 PF09725.4 KFY02799.1 - 0.09 12.8 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 FSH1 PF03959.8 KFY02809.1 - 2.3e-27 95.8 0.0 2.3e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFY02809.1 - 0.0032 17.3 0.0 0.0053 16.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BTB PF00651.26 KFY02810.1 - 0.00031 20.7 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1415 PF07209.7 KFY02810.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) APH PF01636.18 KFY02815.1 - 1.4e-13 51.1 0.1 3.1e-13 50.0 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY02815.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFY02815.1 - 0.0041 16.4 0.1 0.28 10.5 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KFY02815.1 - 0.12 11.4 0.0 11 5.0 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 KFY02815.1 - 0.21 10.1 0.0 0.67 8.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) PufQ PF05398.6 KFY02817.1 - 0.1 12.6 0.2 24 5.0 0.0 2.6 1 1 2 3 3 3 0 PufQ cytochrome subunit E1-E2_ATPase PF00122.15 KFY02820.1 - 3.7e-26 91.5 0.1 8.1e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KFY02820.1 - 4.6e-12 45.2 0.1 1.1e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Methyltransf_31 PF13847.1 KFY02829.1 - 1.4e-13 50.6 0.1 2e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY02829.1 - 3e-11 43.6 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY02829.1 - 5.3e-07 28.9 0.0 7.4e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFY02829.1 - 1.7e-05 25.1 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY02829.1 - 0.00016 21.4 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY02829.1 - 0.00037 20.8 0.0 0.00063 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02829.1 - 0.00047 20.6 0.0 0.00095 19.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFY02829.1 - 0.0023 17.6 0.0 0.0028 17.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KFY02829.1 - 0.0034 17.3 0.0 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.2 KFY02836.1 - 4.8e-12 46.0 0.0 1.1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Cupin_1 PF00190.17 KFY02836.1 - 2.3e-11 43.3 0.1 4.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Cupin Ank PF00023.25 KFY02836.1 - 2.5e-08 33.2 0.0 0.0088 15.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFY02836.1 - 3.3e-08 33.8 0.0 2.5e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY02836.1 - 5.1e-07 29.7 0.0 0.00017 21.7 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02836.1 - 1.4e-06 27.9 0.0 0.03 14.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Cupin_2 PF07883.6 KFY02836.1 - 0.00024 20.5 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Glucos_trans_II PF14264.1 KFY02837.1 - 0.69 8.8 10.1 0.65 8.9 5.8 1.8 1 1 0 1 1 1 0 Glucosyl transferase GtrII Terpene_synth_C PF03936.11 KFY02838.1 - 0.00019 20.7 0.1 0.0003 20.1 0.1 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain AMP-binding PF00501.23 KFY02868.1 - 7.2e-08 31.2 0.0 9.1e-08 30.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY02868.1 - 0.00033 21.5 0.0 0.00053 20.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LTXXQ PF07813.7 KFY02869.1 - 0.035 14.5 0.1 0.056 13.9 0.1 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein DUF3260 PF11658.3 KFY02869.1 - 0.052 11.6 0.1 0.059 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Adipogenin PF15202.1 KFY02871.1 - 0.017 15.0 0.3 0.041 13.7 0.0 1.8 2 0 0 2 2 2 0 Adipogenin PGP_phosphatase PF09419.5 KFY02872.1 - 4.7e-49 165.9 0.0 7.9e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KFY02872.1 - 0.0042 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like F-box-like PF12937.2 KFY02872.1 - 0.0056 16.3 0.9 0.024 14.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KFY02872.1 - 0.14 11.8 0.4 2 8.1 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain LSM PF01423.17 KFY02873.1 - 4.4e-14 51.7 0.4 5.7e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFY02873.1 - 0.035 14.0 0.1 0.061 13.2 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain E1-E2_ATPase PF00122.15 KFY02874.1 - 7.8e-19 67.6 0.2 2.3e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY02874.1 - 2.4e-17 64.0 0.1 4.3e-16 59.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY02874.1 - 1.5e-13 51.3 0.3 1.4e-12 48.2 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY02874.1 - 7.8e-11 41.7 0.0 2.9e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFY02874.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Myb_DNA-bind_6 PF13921.1 KFY02875.1 - 1.3e-12 47.6 0.0 4e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFY02875.1 - 7.7e-09 35.4 0.2 6.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PRP8_domainIV PF12134.3 KFY02877.1 - 1e-125 417.6 2.1 1e-125 417.6 1.4 1.7 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KFY02877.1 - 1.3e-64 216.3 0.1 2.9e-64 215.2 0.1 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PROCT PF08084.6 KFY02877.1 - 1.1e-46 157.6 0.2 5.3e-46 155.3 0.0 2.3 2 0 0 2 2 2 1 PROCT (NUC072) domain Hom_end_hint PF05203.11 KFY02877.1 - 1e-10 41.7 2.2 4.5e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Hom_end-associated Hint OCD_Mu_crystall PF02423.10 KFY02877.1 - 0.053 12.2 1.4 0.086 11.5 0.9 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 KFY02878.1 - 1.1e-37 128.1 3.9 1.4e-37 127.7 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 KFY02878.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 KFY02878.1 - 0.89 9.2 4.5 8.1 6.1 0.1 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Alk_phosphatase PF00245.15 KFY02879.1 - 4.7e-109 364.8 0.0 5.7e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase RskA PF10099.4 KFY02879.1 - 0.0011 18.6 0.1 0.0036 17.0 0.0 1.8 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Metalloenzyme PF01676.13 KFY02879.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF498 PF04430.9 KFY02880.1 - 2.8e-29 100.8 0.0 4.1e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pkinase PF00069.20 KFY02893.1 - 8.1e-06 25.1 0.3 1.4e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KFY02893.1 - 9.8e-06 25.4 0.0 0.0047 16.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFY02893.1 - 0.001 18.1 0.1 0.0018 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFY02893.1 - 0.046 13.0 0.1 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 KFY02906.1 - 7e-07 28.6 0.0 0.037 13.1 0.0 3.0 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02906.1 - 1.2e-05 24.5 0.0 0.0038 16.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase DUF4644 PF15486.1 KFY02909.1 - 0.044 13.7 0.5 0.071 13.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) COesterase PF00135.23 KFY02916.1 - 2.8e-91 306.8 0.0 7.9e-91 305.3 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Sec1 PF00995.18 KFY02916.1 - 2.3e-22 79.3 0.0 3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Abhydrolase_3 PF07859.8 KFY02916.1 - 4.1e-07 29.7 0.0 8.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFY02916.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family RTA1 PF04479.8 KFY02917.1 - 1.8e-18 66.8 0.5 2.1e-18 66.6 0.3 1.0 1 0 0 1 1 1 1 RTA1 like protein Amidohydro_4 PF13147.1 KFY02918.1 - 9.2e-19 68.5 0.1 2.2e-17 63.9 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFY02918.1 - 2.5e-14 53.6 0.1 3.3e-12 46.7 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFY02918.1 - 8.4e-11 41.7 1.4 6e-08 32.3 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFY02918.1 - 2.2e-08 33.8 0.3 6.9e-08 32.2 0.2 1.9 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans_2 PF11951.3 KFY02918.1 - 2.4e-05 23.1 0.5 0.0002 20.1 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02918.1 - 0.0028 17.5 0.9 0.0056 16.5 0.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 KFY02925.1 - 1.4e-47 161.6 2.5 3.7e-47 160.2 1.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFY02925.1 - 7.5e-18 65.7 0.0 1.7e-17 64.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFY02925.1 - 4.8e-17 61.1 0.1 1.1e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 KFY02925.1 - 1.7e-14 53.7 2.1 1.7e-14 53.7 1.4 2.7 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.2 KFY02925.1 - 2.3e-13 50.7 0.3 4.6e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY02925.1 - 2e-07 30.8 0.1 9.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_efflux PF01545.16 KFY02927.1 - 6e-69 232.2 4.1 6.7e-69 232.0 2.9 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 KFY02927.1 - 0.0094 14.9 0.3 0.0094 14.9 0.2 1.9 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component Na_H_Exchanger PF00999.16 KFY02927.1 - 0.17 10.3 9.2 0.0083 14.7 2.0 1.8 2 0 0 2 2 2 0 Sodium/hydrogen exchanger family Sugar_tr PF00083.19 KFY02930.1 - 5.1e-36 124.2 27.5 2.2e-35 122.1 19.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02930.1 - 6.5e-32 110.6 31.1 1.1e-26 93.4 7.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KFY02930.1 - 5.6e-05 22.0 5.1 0.0066 15.1 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF791) DDE_1 PF03184.14 KFY02931.1 - 1.4e-22 79.8 0.0 2.5e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KFY02931.1 - 3.9e-05 23.3 0.4 9e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Sugar_tr PF00083.19 KFY02932.1 - 1.3e-16 60.2 2.1 1.6e-16 59.9 1.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02932.1 - 0.0024 16.6 0.6 0.0027 16.4 0.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-LITAF-like PF10601.4 KFY02932.1 - 0.076 12.8 0.2 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Ycf66_N PF07444.6 KFY02932.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ycf66 protein N-terminus ICAT PF06384.6 KFY02937.1 - 0.058 13.1 0.3 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Ank_2 PF12796.2 KFY02998.1 - 1.7e-33 114.8 8.6 8.7e-19 67.6 0.7 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02998.1 - 1.1e-29 100.6 16.7 8.8e-07 28.4 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFY02998.1 - 4.1e-25 87.6 3.3 1.4e-08 35.0 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02998.1 - 1.8e-12 46.2 9.4 0.12 12.6 0.0 6.3 6 0 0 6 6 5 4 Ankyrin repeat Ank_5 PF13857.1 KFY02998.1 - 1.7e-08 34.4 8.1 0.0024 18.0 0.7 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 KFY02998.1 - 1.2e-06 28.2 0.2 2.3e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 NACHT domain HR1 PF02185.11 KFY02998.1 - 0.006 16.3 0.7 0.022 14.4 0.1 2.2 2 0 0 2 2 2 1 Hr1 repeat PMEI PF04043.10 KFY02998.1 - 0.044 13.6 0.3 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Syntaxin_2 PF14523.1 KFY02998.1 - 0.048 13.6 3.7 0.28 11.2 0.8 2.8 2 1 1 3 3 3 0 Syntaxin-like protein BAR PF03114.13 KFY02998.1 - 0.062 12.7 0.8 0.13 11.7 0.6 1.5 1 0 0 1 1 1 0 BAR domain AAA_13 PF13166.1 KFY02998.1 - 0.068 11.6 3.4 0.13 10.7 2.3 1.3 1 0 0 1 1 1 0 AAA domain FtsJ PF01728.14 KFY03000.1 - 5.9e-12 45.9 0.0 9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFY03000.1 - 0.029 14.9 0.0 0.07 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RRN7 PF11781.3 KFY03002.1 - 0.028 13.9 0.2 0.054 13.0 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Sulf_transp PF04143.9 KFY03003.1 - 2.3e-13 49.9 28.5 3.9e-09 36.3 4.7 4.9 4 1 1 5 5 5 3 Sulphur transport DUF4341 PF14241.1 KFY03003.1 - 0.00039 20.0 0.5 0.00039 20.0 0.3 4.3 4 2 0 4 4 4 1 Domain of unknown function (DUF4341) Lactamase_B PF00753.22 KFY03004.1 - 7.5e-18 64.8 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1275 PF06912.6 KFY03005.1 - 1.5e-47 161.5 12.2 1.7e-47 161.3 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Tim17 PF02466.14 KFY03005.1 - 0.055 13.5 0.3 0.055 13.5 0.2 2.5 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family SirB PF04247.7 KFY03005.1 - 0.54 9.9 2.8 2.9 7.6 0.4 2.9 1 1 2 3 3 3 0 Invasion gene expression up-regulator, SirB ABC2_membrane PF01061.19 KFY03006.1 - 2.3e-28 98.8 26.4 3.7e-28 98.1 18.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFY03006.1 - 4e-27 95.1 0.1 6.1e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY03006.1 - 3.2e-09 37.1 0.3 0.00013 21.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KFY03006.1 - 7.6e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KFY03006.1 - 2e-05 24.1 0.0 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KFY03006.1 - 4.8e-05 22.8 0.1 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KFY03006.1 - 7.2e-05 22.1 0.0 0.00041 19.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFY03006.1 - 0.00015 21.8 0.1 0.00044 20.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KFY03006.1 - 0.00022 20.4 0.0 0.31 10.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KFY03006.1 - 0.00047 20.9 0.0 0.00097 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFY03006.1 - 0.00061 19.7 0.1 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFY03006.1 - 0.00063 18.9 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFY03006.1 - 0.0011 18.4 0.3 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KFY03006.1 - 0.0012 18.2 0.2 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 KFY03006.1 - 0.0017 17.3 0.1 0.0028 16.6 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.9 KFY03006.1 - 0.002 17.8 0.1 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KFY03006.1 - 0.0024 18.1 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFY03006.1 - 0.0027 17.6 0.1 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFY03006.1 - 0.0037 16.9 0.1 0.0066 16.1 0.1 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KFY03006.1 - 0.0037 16.7 0.1 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFY03006.1 - 0.0039 16.9 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KFY03006.1 - 0.0065 15.9 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KFY03006.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KFY03006.1 - 0.02 14.5 0.2 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFY03006.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 KFY03006.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFY03006.1 - 0.032 13.9 0.1 0.18 11.5 0.1 2.1 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 KFY03006.1 - 0.032 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_35 PF14516.1 KFY03006.1 - 0.058 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 KFY03006.1 - 0.072 12.5 0.3 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KFY03006.1 - 0.076 13.3 0.1 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 KFY03006.1 - 0.077 12.2 0.2 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 KFY03006.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 KFY03006.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA PF00004.24 KFY03006.1 - 0.094 12.9 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KFY03006.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 KFY03006.1 - 0.37 9.1 0.2 4.7 5.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TMPIT PF07851.8 KFY03006.1 - 8 5.4 9.4 14 4.6 6.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Fungal_trans PF04082.13 KFY03007.1 - 1.5e-06 27.2 0.2 4.2e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFY03008.1 - 2.6e-10 39.6 0.1 4.3e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03008.1 - 1.1e-09 38.0 12.3 2e-09 37.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDO_I PF05995.7 KFY03009.1 - 1.8e-36 124.9 0.7 1.9e-36 124.8 0.5 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFY03009.1 - 0.0034 16.7 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) RFC1 PF08519.7 KFY03009.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain AOX PF01786.12 KFY03010.1 - 1e-81 273.2 0.1 1.7e-81 272.5 0.0 1.4 1 0 0 1 1 1 1 Alternative oxidase zf-MYND PF01753.13 KFY03025.1 - 3e-09 36.6 15.4 3e-09 36.6 10.7 2.8 3 0 0 3 3 3 1 MYND finger RdRP PF05183.7 KFY03027.1 - 2.9e-165 551.2 0.0 4.3e-165 550.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DEAD PF00270.24 KFY03028.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase NDT80_PhoG PF05224.7 KFY03030.1 - 2.5e-41 141.7 0.0 3.5e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Myb_DNA-binding PF00249.26 KFY03030.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA PF00004.24 KFY03031.1 - 1.6e-41 141.5 0.0 2.4e-12 47.2 0.0 5.6 5 1 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 KFY03031.1 - 1.5e-39 135.4 0.0 4.6e-39 133.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFY03031.1 - 7.4e-28 97.7 22.9 3.2e-25 89.0 0.0 6.7 5 1 0 6 6 5 1 AAA domain AAA_19 PF13245.1 KFY03031.1 - 3e-20 71.7 1.3 5.3e-07 29.2 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_5 PF07728.9 KFY03031.1 - 1.2e-12 47.7 0.2 0.0044 16.7 0.0 4.9 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFY03031.1 - 2.7e-12 46.9 9.1 0.0088 16.1 0.0 7.4 5 3 0 5 5 5 3 AAA domain AAA_17 PF13207.1 KFY03031.1 - 2.8e-11 44.2 15.3 0.028 15.2 0.0 6.2 6 0 0 6 6 4 4 AAA domain Mg_chelatase PF01078.16 KFY03031.1 - 2.3e-10 39.9 0.1 0.22 10.6 0.0 4.6 4 0 0 4 4 4 4 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFY03031.1 - 2.8e-09 36.8 18.2 0.0028 17.2 0.0 7.2 7 1 0 7 7 5 3 AAA domain Viral_helicase1 PF01443.13 KFY03031.1 - 4.1e-09 36.3 0.1 0.75 9.2 0.0 5.7 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KFY03031.1 - 1.9e-08 34.6 7.0 0.38 11.0 0.0 6.1 5 0 0 5 5 5 3 AAA domain IstB_IS21 PF01695.12 KFY03031.1 - 7.6e-08 31.9 0.1 2.2 7.6 0.0 4.8 4 0 0 4 4 4 2 IstB-like ATP binding protein RNA_helicase PF00910.17 KFY03031.1 - 2.3e-06 27.7 0.1 4.3 7.5 0.0 4.7 4 0 0 4 4 4 1 RNA helicase AAA_33 PF13671.1 KFY03031.1 - 3.7e-06 26.8 13.1 0.18 11.6 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.1 KFY03031.1 - 1.4e-05 24.7 5.6 1.1 8.7 0.0 4.4 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KFY03031.1 - 9.3e-05 22.4 25.3 0.44 10.5 0.0 6.6 6 0 0 6 6 5 3 AAA ATPase domain DUF2075 PF09848.4 KFY03031.1 - 0.00011 21.2 9.8 0.025 13.5 0.0 6.4 7 1 0 7 7 7 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KFY03031.1 - 0.00012 21.5 0.3 1.8 8.0 0.1 5.1 4 1 0 4 4 4 1 Sigma-54 interaction domain Torsin PF06309.6 KFY03031.1 - 0.00044 20.1 0.1 35 4.3 0.0 4.4 4 0 0 4 4 4 0 Torsin CAF-1_p150 PF11600.3 KFY03031.1 - 0.0026 17.1 25.0 0.0026 17.1 17.3 3.4 4 0 0 4 4 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal KaiC PF06745.8 KFY03031.1 - 0.0038 16.3 1.7 7.3 5.6 0.0 4.2 4 0 0 4 4 4 0 KaiC ResIII PF04851.10 KFY03031.1 - 0.0051 16.6 11.8 0.14 11.9 0.0 5.6 5 1 1 6 6 5 1 Type III restriction enzyme, res subunit NACHT PF05729.7 KFY03031.1 - 0.012 15.2 1.3 11 5.5 0.0 4.3 4 0 0 4 4 4 0 NACHT domain UvrD_C_2 PF13538.1 KFY03031.1 - 0.013 15.6 0.0 0.055 13.6 0.0 2.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NTPase_1 PF03266.10 KFY03031.1 - 0.082 12.6 3.1 9 5.9 0.0 4.1 4 0 0 4 4 4 0 NTPase AAA_3 PF07726.6 KFY03031.1 - 0.11 12.1 0.1 44 3.6 0.0 3.9 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Macoilin PF09726.4 KFY03031.1 - 0.78 7.9 31.1 0.88 7.7 9.9 2.4 2 0 0 2 2 2 0 Transmembrane protein Pet127 PF08634.5 KFY03032.1 - 0.0013 17.9 0.1 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial protein Pet127 GHL1-3 PF11308.3 KFY03032.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 Piwi PF02171.12 KFY03033.1 - 7.2e-67 225.4 0.0 1.2e-66 224.7 0.0 1.4 1 0 0 1 1 1 1 Piwi domain Ribonuclease_3 PF00636.21 KFY03033.1 - 8.6e-47 158.3 0.0 7.3e-22 77.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFY03033.1 - 1.1e-34 119.1 0.0 3.8e-16 59.2 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 KFY03033.1 - 2.5e-22 78.4 0.0 1.2e-21 76.2 0.0 2.3 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 KFY03033.1 - 6.4e-19 68.0 0.0 1.6e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cauli_VI PF01693.11 KFY03033.1 - 8.8e-14 51.2 4.1 1.9e-06 27.8 0.5 2.8 2 0 0 2 2 2 2 Caulimovirus viroplasmin Helicase_C PF00271.26 KFY03033.1 - 1.3e-11 44.1 0.0 3.8e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IBR PF01485.16 KFY03033.1 - 9.3e-11 41.4 37.1 2.1e-05 24.2 6.1 3.7 3 0 0 3 3 3 2 IBR domain DUF1785 PF08699.5 KFY03033.1 - 1.3e-10 40.4 0.4 3.2e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ResIII PF04851.10 KFY03033.1 - 5.7e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PAZ PF02170.17 KFY03033.1 - 1.7e-08 33.8 0.0 5.2e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 PAZ domain Flavi_DEAD PF07652.9 KFY03033.1 - 0.0027 17.4 0.1 0.0097 15.6 0.1 1.9 1 1 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 KFY03033.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RdRP PF05183.7 KFY03034.1 - 3.5e-126 422.2 0.0 5.6e-126 421.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.1 KFY03034.1 - 6.8e-51 172.4 0.1 1.1e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFY03034.1 - 4.5e-45 154.0 2.2 2.1e-43 148.6 1.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFY03034.1 - 1e-12 48.0 0.1 5.7e-12 45.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFY03034.1 - 1.2e-10 40.9 0.1 5.4e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 KFY03034.1 - 1.3e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFY03034.1 - 8.4e-06 25.4 2.5 0.076 12.5 0.2 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KFY03034.1 - 3.4e-05 23.5 0.0 6.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KFY03034.1 - 0.00017 21.0 0.2 0.055 12.7 0.0 2.8 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KFY03034.1 - 0.00019 20.7 0.0 0.00078 18.7 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.24 KFY03034.1 - 0.00068 19.8 0.0 0.0037 17.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFY03034.1 - 0.0013 18.9 0.1 0.0058 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KFY03034.1 - 0.0029 17.1 0.0 0.0083 15.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 KFY03034.1 - 0.0034 17.4 0.1 0.008 16.2 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KFY03034.1 - 0.004 17.1 0.4 0.011 15.7 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain DUF2075 PF09848.4 KFY03034.1 - 0.044 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KFY03034.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF968 PF06147.6 KFY03034.1 - 0.17 11.7 0.1 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF968) AAA_28 PF13521.1 KFY03035.1 - 2.1e-27 96.0 0.0 2.4e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY03035.1 - 0.00093 19.5 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY03035.1 - 0.0014 18.6 0.1 0.0031 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFY03035.1 - 0.0019 18.9 0.2 0.0077 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KFY03035.1 - 0.0064 16.2 0.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFY03035.1 - 0.0086 15.9 0.1 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFY03035.1 - 0.009 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase MMR_HSR1 PF01926.18 KFY03035.1 - 0.018 14.9 0.0 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 KFY03035.1 - 0.03 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KFY03035.1 - 0.05 14.0 0.1 0.068 13.6 0.1 1.5 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KFY03035.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Dynamin family AAA PF00004.24 KFY03035.1 - 0.076 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFY03035.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KFY03035.1 - 0.089 12.9 0.0 0.42 10.7 0.0 1.9 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 KFY03035.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KFY03035.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation muHD PF10291.4 KFY03037.1 - 0.086 12.0 0.1 0.099 11.8 0.1 1.1 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ADK PF00406.17 KFY03038.1 - 6.7e-17 61.7 0.1 5.7e-09 36.0 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_33 PF13671.1 KFY03038.1 - 1.4e-07 31.4 0.1 0.0036 17.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 KFY03038.1 - 2.5e-06 28.2 0.0 6.9e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY03038.1 - 0.00011 22.5 0.1 0.18 12.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 KFY03038.1 - 0.00013 21.4 0.5 0.0061 15.9 0.2 2.2 1 1 1 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 KFY03038.1 - 0.0056 15.7 0.2 0.45 9.5 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin AAA_22 PF13401.1 KFY03038.1 - 0.0088 16.1 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CYTH PF01928.16 KFY03039.1 - 8.8e-11 41.8 0.0 1.6e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 CYTH domain UPRTase PF14681.1 KFY03040.1 - 1.1e-40 139.0 0.1 2.2e-40 138.1 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 KFY03040.1 - 3.3e-08 33.9 0.0 1.7e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_33 PF13671.1 KFY03040.1 - 1.4e-06 28.2 0.0 2.4e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFY03040.1 - 8.5e-06 26.5 0.0 2.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY03040.1 - 5.4e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFY03040.1 - 0.00055 19.0 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 KFY03040.1 - 0.00059 19.8 0.3 0.004 17.1 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain PRTase_2 PF15609.1 KFY03040.1 - 0.00087 18.6 0.0 0.0043 16.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase Hydrolase PF00702.21 KFY03040.1 - 0.0024 18.3 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.22 KFY03040.1 - 0.0028 17.3 0.3 0.058 13.1 0.1 2.7 1 1 1 2 2 2 1 Phosphoribosyl transferase domain ArgK PF03308.11 KFY03040.1 - 0.0077 15.0 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 KFY03040.1 - 0.013 14.5 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 KFY03040.1 - 0.015 15.4 0.1 0.073 13.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KFY03040.1 - 0.021 13.7 0.0 0.047 12.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KFY03040.1 - 0.03 14.4 0.1 0.31 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KFY03040.1 - 0.056 12.8 0.1 1 8.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 KFY03040.1 - 0.058 13.2 0.0 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KFY03040.1 - 0.071 12.5 0.1 0.33 10.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Response_reg PF00072.19 KFY03040.1 - 0.09 12.7 0.1 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain DAP3 PF10236.4 KFY03040.1 - 0.099 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 KFY03040.1 - 0.11 12.4 0.1 1.1 9.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFY03040.1 - 0.14 11.8 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase MSA_2 PF00985.12 KFY03042.1 - 0.69 10.0 9.3 0.93 9.6 6.4 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family BTB PF00651.26 KFY03043.1 - 1e-06 28.7 0.1 1.9e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF2368 PF10166.4 KFY03043.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Glyco_hydro_76 PF03663.9 KFY03063.1 - 5.1e-91 305.8 5.7 6.1e-91 305.5 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 F-box-like PF12937.2 KFY03065.1 - 0.001 18.7 0.5 0.001 18.7 0.3 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KFY03065.1 - 2.1 8.0 8.7 0.11 12.2 0.3 2.9 3 0 0 3 3 3 0 F-box domain Aldedh PF00171.17 KFY03066.1 - 1.5e-130 435.6 0.2 1.8e-130 435.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.3 KFY03067.1 - 2.2e-22 79.2 0.2 6.4e-22 77.6 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03067.1 - 2.1e-07 30.7 13.4 4.7e-07 29.6 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 KFY03067.1 - 0.59 9.7 3.8 0.94 9.0 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) ADH_zinc_N PF00107.21 KFY03068.1 - 4.5e-26 90.9 0.5 7.4e-26 90.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY03068.1 - 2e-15 56.4 0.0 2.8e-12 46.3 0.0 2.6 2 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFY03068.1 - 9e-12 45.9 0.0 2.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 KFY03068.1 - 0.0062 16.1 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ICL PF00463.16 KFY03069.1 - 6.5e-197 654.8 0.2 7.5e-197 654.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFY03069.1 - 1.1e-10 41.1 0.0 8.7e-10 38.2 0.0 2.0 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KFY03069.1 - 0.041 13.3 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF2458 PF10454.4 KFY03069.1 - 0.079 12.8 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Gp_dh_C PF02800.15 KFY03069.1 - 0.16 11.4 2.2 4.6 6.6 0.1 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GFO_IDH_MocA_C PF02894.12 KFY03070.1 - 5e-17 61.7 0.1 1.2e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 KFY03070.1 - 7e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF4356 PF14266.1 KFY03070.1 - 0.06 11.7 0.0 0.081 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4356) Glyco_hyd_65N_2 PF14498.1 KFY03071.1 - 0.033 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 KFY03072.1 - 4.6e-66 223.2 16.8 5.3e-66 223.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03072.1 - 1.4e-19 70.0 24.9 4.6e-13 48.6 3.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 KFY03073.1 - 1.3e-67 227.8 3.0 1.8e-67 227.4 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Reg_prop PF07494.6 KFY03073.1 - 0.21 11.7 2.0 24 5.3 0.1 3.7 3 0 0 3 3 3 0 Two component regulator propeller WD40 PF00400.27 KFY03079.1 - 1.5e-153 493.8 47.6 5.7e-14 51.3 0.1 13.4 13 0 0 13 13 13 12 WD domain, G-beta repeat PD40 PF07676.7 KFY03079.1 - 8.8e-21 73.1 1.1 0.67 9.6 0.0 11.4 12 0 0 12 12 12 6 WD40-like Beta Propeller Repeat NACHT PF05729.7 KFY03079.1 - 4.4e-11 42.7 0.2 1.1e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Proteasome_A_N PF10584.4 KFY03079.1 - 4.1e-08 32.3 0.6 4.8 6.6 0.0 9.1 12 0 0 12 12 12 1 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 KFY03079.1 - 0.0022 16.2 0.0 0.75 7.9 0.0 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF3312) HTH_psq PF05225.11 KFY03079.1 - 0.059 12.9 0.7 0.29 10.7 0.2 2.2 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Patatin PF01734.17 KFY03083.1 - 9.4e-10 38.7 0.0 2.7e-09 37.2 0.0 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase DUF605 PF04652.11 KFY03098.1 - 0.037 13.4 27.2 0.046 13.1 18.8 1.3 1 0 0 1 1 1 0 Vta1 like DUF1388 PF07142.7 KFY03098.1 - 0.047 13.4 1.4 0.047 13.4 1.0 5.7 2 2 2 5 5 5 0 Repeat of unknown function (DUF1388) F-112 PF09645.5 KFY03099.1 - 0.088 12.6 0.2 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 F-112 protein Macoilin PF09726.4 KFY03101.1 - 2.6 6.2 6.5 3.4 5.8 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4232 PF14016.1 KFY03106.1 - 0.02 14.5 0.2 0.035 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) SEF14_adhesin PF06443.6 KFY03106.1 - 0.095 12.3 0.4 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 SEF14-like adhesin DUF929 PF06053.6 KFY03107.1 - 0.048 12.7 0.1 0.21 10.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF929) APH PF01636.18 KFY03108.1 - 1.8e-14 54.0 0.0 3.9e-14 52.9 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFY03108.1 - 4.6e-07 28.8 0.0 7.8e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 KFY03108.1 - 0.00019 20.6 0.0 0.00043 19.5 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFY03108.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ofd1_CTDD PF10637.4 KFY03108.1 - 0.032 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term RRM_1 PF00076.17 KFY03112.1 - 1.6e-07 30.8 0.0 3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03112.1 - 9.9e-07 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03112.1 - 0.00021 21.1 0.0 0.0006 19.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Transket_pyr PF02779.19 KFY03113.1 - 7.1e-47 159.1 0.0 1.1e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFY03113.1 - 2.5e-35 121.1 0.0 7.4e-35 119.5 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.5 KFY03113.1 - 4.4e-20 71.4 0.0 9e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KFY03113.1 - 7.8e-18 64.7 0.0 1.9e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY03113.1 - 2.8e-16 59.4 0.0 7.3e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFY03113.1 - 3.4e-12 46.0 0.1 5.3e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFY03113.1 - 4.9e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY03113.1 - 5.5e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY03113.1 - 1.9e-11 44.5 0.0 5.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY03113.1 - 1.2e-09 38.4 0.0 3.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY03113.1 - 8e-09 34.9 0.0 4.1e-08 32.6 0.0 2.1 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFY03113.1 - 3.6e-08 33.4 0.0 1.3e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY03113.1 - 6.4e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFY03113.1 - 0.00013 21.6 0.1 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KFY03113.1 - 0.00059 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 KFY03113.1 - 0.0006 19.4 0.1 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.13 KFY03113.1 - 0.015 14.4 2.4 0.023 13.9 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 KFY03113.1 - 0.019 15.7 0.0 0.076 13.8 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.15 KFY03113.1 - 0.028 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Aminotran_5 PF00266.14 KFY03113.1 - 0.094 11.4 0.0 0.35 9.5 0.0 1.9 3 0 0 3 3 3 0 Aminotransferase class-V MetW PF07021.7 KFY03113.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF972 PF06156.8 KFY03113.1 - 0.17 12.2 0.6 0.46 10.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) BMF PF15185.1 KFY03114.1 - 0.021 14.1 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis PQ-loop PF04193.9 KFY03117.1 - 1.4e-21 75.7 8.1 2.3e-13 49.4 1.9 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF2512 PF10710.4 KFY03117.1 - 2 7.8 6.2 2.4 7.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Med8 PF10232.4 KFY03118.1 - 5.3e-29 101.3 0.0 7.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF937 PF06078.6 KFY03118.1 - 0.051 13.7 1.3 0.16 12.1 0.1 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Acetyltransf_1 PF00583.19 KFY03119.1 - 5e-12 45.6 0.0 7.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY03119.1 - 1.1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY03119.1 - 2.2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFY03119.1 - 0.001 19.2 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFY03119.1 - 0.0021 18.0 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFY03119.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY03119.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Complex1_LYR PF05347.10 KFY03120.1 - 6.1e-15 54.7 0.1 1.1e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFY03120.1 - 9.9e-14 51.2 0.9 1.3e-13 50.9 0.1 1.6 1 1 1 2 2 2 1 Complex1_LYR-like RecO_N PF11967.3 KFY03120.1 - 0.034 13.9 0.6 0.39 10.5 0.1 2.2 1 1 1 2 2 2 0 Recombination protein O N terminal PIG-S PF10510.4 KFY03121.1 - 4.7e-106 355.5 0.0 6.3e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Ribosomal_L36 PF00444.13 KFY03121.1 - 4.1e-17 61.8 8.2 4.1e-17 61.8 5.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L36 Acetyltransf_7 PF13508.1 KFY03123.1 - 0.015 15.3 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY03123.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Methyltransf_23 PF13489.1 KFY03124.1 - 2e-18 66.5 0.0 5.9e-18 65.1 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY03124.1 - 5.2e-08 33.2 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY03124.1 - 1.5e-07 31.9 0.0 7.5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY03124.1 - 3.4e-07 30.6 0.0 1.5e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY03124.1 - 1.4e-05 24.6 0.0 0.00015 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY03124.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KFY03124.1 - 0.0012 18.0 0.0 0.0049 16.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KFY03124.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KFY03124.1 - 0.0014 18.9 0.0 0.0038 17.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY03124.1 - 0.0029 16.7 0.0 0.043 12.9 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KFY03124.1 - 0.019 14.0 0.0 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.7 KFY03124.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.10 KFY03124.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HET-s_218-289 PF11558.3 KFY03127.1 - 2.1e-05 24.4 0.4 4.9e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Het-s 218-289 Vac14_Fig4_bd PF11916.3 KFY03127.1 - 0.0055 15.8 0.1 0.0091 15.1 0.1 1.2 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Atg14 PF10186.4 KFY03128.1 - 4.8e-05 22.4 3.5 8.4e-05 21.6 2.4 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 WEMBL PF05701.6 KFY03128.1 - 0.00035 19.1 1.8 0.00071 18.1 1.2 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light PHD PF00628.24 KFY03128.1 - 0.0022 17.6 11.8 0.0054 16.3 8.2 1.7 1 0 0 1 1 1 1 PHD-finger Peptidase_C48 PF02902.14 KFY03128.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IFT57 PF10498.4 KFY03128.1 - 0.33 9.6 5.8 0.18 10.4 1.9 2.0 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Ank_2 PF12796.2 KFY03130.1 - 2e-16 60.0 13.0 0.67 10.3 0.1 10.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03130.1 - 1.6e-13 49.7 16.9 36 4.4 0.0 19.2 25 2 0 25 25 23 0 Ankyrin repeat AAA_16 PF13191.1 KFY03130.1 - 9.2e-07 29.0 0.0 8.7e-06 25.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KFY03130.1 - 2.9e-05 23.7 0.0 6.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain INTS5_C PF14838.1 KFY03130.1 - 6.8e-05 21.3 4.6 0.99 7.6 0.1 5.8 2 2 3 7 7 7 2 Integrator complex subunit 5 C-terminus Avirulence PF03377.8 KFY03130.1 - 8.6e-05 21.4 12.3 0.087 11.5 0.2 4.3 1 1 3 5 5 5 4 Xanthomonas avirulence protein, Avr/PthA Cutinase PF01083.17 KFY03130.1 - 0.00016 21.4 0.0 0.00043 20.0 0.0 1.7 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 KFY03130.1 - 0.00031 20.7 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KFY03130.1 - 0.00044 20.3 0.0 0.016 15.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain Abhydrolase_5 PF12695.2 KFY03130.1 - 0.0024 17.6 0.0 0.0097 15.6 0.0 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KFY03130.1 - 0.0024 17.0 0.0 0.0051 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Arabinose_Iso_C PF11762.3 KFY03130.1 - 0.0037 16.8 2.0 7.6 6.1 0.0 4.4 5 0 0 5 5 5 1 L-arabinose isomerase C-terminal domain PGAP1 PF07819.8 KFY03130.1 - 0.0089 15.6 0.0 0.047 13.2 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 KFY03130.1 - 0.019 14.5 0.0 0.085 12.4 0.0 2.2 1 0 0 1 1 1 0 Lipase (class 3) DUF2892 PF11127.3 KFY03130.1 - 0.021 14.6 7.1 2.9 7.7 0.0 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2892) DUF4350 PF14258.1 KFY03130.1 - 0.025 14.7 2.2 55 4.0 0.0 7.3 8 2 2 10 10 9 0 Domain of unknown function (DUF4350) RNA_helicase PF00910.17 KFY03130.1 - 0.045 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Thioesterase PF00975.15 KFY03130.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 KFY03130.1 - 0.095 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Spc7_N PF15402.1 KFY03131.1 - 7.9e-249 828.3 72.5 2e-248 827.0 50.3 2.4 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KFY03131.1 - 6.4e-107 356.9 5.8 1.2e-106 356.1 4.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KFY03131.1 - 2.5e-09 36.6 0.1 5e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17 PF00366.15 KFY03132.1 - 1.2e-29 102.1 0.5 1.7e-29 101.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 PfkB PF00294.19 KFY03133.1 - 4.7e-39 134.3 1.0 5.5e-39 134.0 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF498 PF04430.9 KFY03133.1 - 0.047 13.2 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Zn_clus PF00172.13 KFY03134.1 - 9.3e-09 35.0 11.1 1.8e-08 34.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY03134.1 - 2.8e-05 22.9 3.9 0.00034 19.3 0.0 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Sugar_tr PF00083.19 KFY03135.1 - 3.3e-106 355.5 33.1 5.8e-106 354.7 22.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03135.1 - 3.6e-21 75.2 61.9 9.6e-13 47.5 19.4 3.6 2 1 2 4 4 4 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFY03135.1 - 1.6e-12 46.7 0.5 3.3e-12 45.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_2 PF13347.1 KFY03135.1 - 2.7e-05 22.7 8.7 2.7e-05 22.7 6.1 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein Methyltransf_23 PF13489.1 KFY03136.1 - 4.7e-12 45.9 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY03136.1 - 7.2e-12 45.6 0.0 2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY03136.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fig1 PF12351.3 KFY03136.1 - 1.9e-10 40.9 5.3 1.9e-10 40.9 3.7 1.5 2 0 0 2 2 1 1 Ca2+ regulator and membrane fusion protein Fig1 Methyltransf_18 PF12847.2 KFY03136.1 - 6.9e-10 39.4 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY03136.1 - 5.2e-08 33.1 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY03136.1 - 1.1e-06 27.9 0.0 1.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFY03136.1 - 2.7e-06 27.7 0.0 9.9e-06 25.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain TPMT PF05724.6 KFY03136.1 - 0.0026 17.2 0.0 0.0067 15.8 0.0 1.6 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 KFY03136.1 - 0.033 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFY03136.1 - 0.038 13.6 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KFY03136.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Claudin_2 PF13903.1 KFY03136.1 - 0.34 10.6 6.6 0.6 9.7 4.6 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.20 KFY03138.1 - 0.00012 21.2 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 KFY03139.1 - 6.4e-13 48.8 19.4 0.0054 17.0 0.1 10.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03139.1 - 2.5e-09 36.4 22.3 20 5.2 0.0 17.9 21 2 0 21 21 21 0 Ankyrin repeat AAA_16 PF13191.1 KFY03139.1 - 3.7e-09 36.8 0.1 2e-08 34.4 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KFY03139.1 - 9.1e-08 31.9 0.0 2.9e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 NACHT domain HTH_Tnp_Tc5 PF03221.11 KFY03139.1 - 1.3e-07 31.3 0.1 7.6 6.4 0.0 9.7 9 2 2 11 11 11 1 Tc5 transposase DNA-binding domain Avirulence PF03377.8 KFY03139.1 - 6.4e-06 25.1 8.3 7.9e-06 24.8 0.3 3.1 2 1 0 3 3 3 1 Xanthomonas avirulence protein, Avr/PthA AAA_22 PF13401.1 KFY03139.1 - 0.00036 20.6 4.9 0.019 15.0 0.0 5.7 4 3 4 8 8 8 1 AAA domain DUF3140 PF11338.3 KFY03139.1 - 0.0098 15.9 0.2 9.6 6.3 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3140) RNA_helicase PF00910.17 KFY03139.1 - 0.024 14.8 0.0 0.12 12.6 0.0 2.3 1 0 0 1 1 1 0 RNA helicase BTB PF00651.26 KFY03140.1 - 0.00035 20.5 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-3CxxC PF13695.1 KFY03141.1 - 1.7e-23 82.7 0.8 3.3e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding domain PsbW PF07123.7 KFY03141.1 - 2.1 8.3 4.6 3.4 7.7 3.2 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Pneumo_att_G PF05539.6 KFY03141.1 - 8.3 5.6 10.3 11 5.2 7.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ank_2 PF12796.2 KFY03146.1 - 2.5e-06 27.7 0.0 3.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03146.1 - 1.3e-05 24.7 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KFY03146.1 - 0.00024 21.0 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFY03146.1 - 0.011 16.2 0.0 1.1 9.9 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY03146.1 - 0.019 15.1 0.0 0.047 13.9 0.0 1.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) E1-E2_ATPase PF00122.15 KFY03151.1 - 1.8e-30 105.7 6.2 1.8e-30 105.7 4.3 1.9 2 1 0 2 2 2 1 E1-E2 ATPase adh_short PF00106.20 KFY03162.1 - 1.2e-16 61.1 0.5 6e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFY03162.1 - 5.6e-05 22.8 0.0 0.00019 21.1 0.0 1.8 2 0 0 2 2 2 1 KR domain HsbA PF12296.3 KFY03162.1 - 0.046 13.5 0.1 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Shikimate_DH PF01488.15 KFY03162.1 - 0.095 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 KFY03163.1 - 1.5e-07 31.2 9.0 2.9e-07 30.2 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COG7 PF10191.4 KFY03163.1 - 0.016 13.1 0.4 0.023 12.6 0.2 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Zn_clus PF00172.13 KFY03164.1 - 5e-09 35.9 9.8 1.5e-08 34.4 6.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY03164.1 - 1.2e-07 30.6 0.1 1.9e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KFY03165.1 - 1.2e-19 70.8 0.1 7e-19 68.3 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY03165.1 - 2.5e-09 37.2 0.0 5.7e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY03165.1 - 5e-09 36.0 0.1 7.1e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY03165.1 - 0.0039 17.2 0.5 0.06 13.3 0.3 2.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY03165.1 - 0.0069 15.8 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY03165.1 - 0.1 11.4 0.0 0.35 9.7 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein DUF3176 PF11374.3 KFY03166.1 - 0.011 15.5 1.0 0.025 14.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) ADH_N PF08240.7 KFY03167.1 - 6.2e-22 77.4 5.4 1.1e-21 76.6 3.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY03167.1 - 2.3e-16 59.5 0.0 4.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFY03167.1 - 0.00015 20.9 0.1 0.00026 20.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFY03167.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFY03167.1 - 0.045 13.5 0.2 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 KFY03167.1 - 0.048 13.2 0.3 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KFY03167.1 - 0.064 13.0 1.5 0.13 12.0 1.0 1.5 1 0 0 1 1 1 0 ThiF family PhzC-PhzF PF02567.11 KFY03168.1 - 4.1e-41 141.0 0.4 9.4e-41 139.8 0.3 1.5 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Amidohydro_3 PF07969.6 KFY03169.1 - 9.9e-57 192.9 1.1 1.2e-56 192.7 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFY03169.1 - 3.2e-08 33.2 0.2 3.2e-08 33.2 0.1 2.5 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KFY03169.1 - 7.4e-05 22.5 0.4 0.29 10.7 0.0 3.4 2 1 0 2 2 2 2 Amidohydrolase family DUF4238 PF14022.1 KFY03170.1 - 1.6e-34 119.4 0.1 2.6e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Ank_2 PF12796.2 KFY03187.1 - 8.6e-68 224.7 0.0 2.6e-15 56.5 0.0 3.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFY03187.1 - 1.3e-35 120.5 0.1 3.8e-11 42.8 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KFY03187.1 - 6.2e-32 107.8 0.0 8.1e-05 22.2 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KFY03187.1 - 2.8e-25 85.8 0.0 0.0012 18.8 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KFY03187.1 - 5.6e-25 87.2 0.2 1.7e-06 28.3 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) F-box PF00646.28 KFY03187.1 - 0.046 13.3 0.2 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 F-box domain S4_2 PF13275.1 KFY03187.1 - 0.15 11.6 2.0 29 4.3 0.0 4.1 5 0 0 5 5 5 0 S4 domain Plug_translocon PF10559.4 KFY03187.1 - 0.19 11.2 1.1 6.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Plug domain of Sec61p Pkinase PF00069.20 KFY03198.1 - 0.0034 16.5 0.0 0.0046 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TPR_2 PF07719.12 KFY03199.1 - 0.0014 18.3 1.9 0.35 10.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFY03199.1 - 0.035 14.7 0.0 12 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFY03199.1 - 0.048 13.5 0.9 0.25 11.3 0.0 2.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03199.1 - 0.089 12.6 1.1 63 3.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Acetyltransf_7 PF13508.1 KFY03200.1 - 0.0097 16.0 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY03200.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ub-Mut7C PF14451.1 KFY03248.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Mut7-C ubiquitin SRF-TF PF00319.13 KFY03252.1 - 0.0022 17.1 0.1 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ferric_reduct PF01794.14 KFY03253.1 - 2.2e-05 24.5 0.0 2.2e-05 24.5 0.0 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component CKS PF01111.14 KFY03258.1 - 3.2e-36 122.9 0.7 4.1e-36 122.6 0.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 KFY03258.1 - 0.1 12.5 1.9 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 APC 15 residue motif Bromodomain PF00439.20 KFY03259.1 - 7e-31 105.9 0.9 1.2e-14 53.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain SpoVG PF04026.7 KFY03259.1 - 0.15 12.0 0.2 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 SpoVG HSP70 PF00012.15 KFY03260.1 - 2.7e-218 725.7 4.6 3.5e-218 725.4 3.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFY03260.1 - 8.7e-15 54.1 0.2 7.3e-11 41.2 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 KFY03260.1 - 0.00012 21.8 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFY03260.1 - 0.0069 16.2 2.5 1.3 8.9 0.1 3.9 3 1 0 3 3 3 1 Cell division protein FtsA NAD-GH PF10712.4 KFY03261.1 - 1.5e-06 26.7 0.0 1.8e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase Pkinase PF00069.20 KFY03263.1 - 6.6e-08 32.0 0.0 9.5e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03263.1 - 0.0045 16.0 0.0 0.0061 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Rad21_Rec8_N PF04825.8 KFY03263.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Toxin_15 PF07906.8 KFY03263.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region AAA PF00004.24 KFY03265.1 - 3.3e-06 27.3 0.0 4.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GRAM PF02893.15 KFY03265.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Vps36_ESCRT-II PF11605.3 KFY03265.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Pkinase PF00069.20 KFY03268.1 - 1.3e-22 80.1 0.0 4.3e-16 58.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03268.1 - 9.3e-05 21.6 0.0 0.0067 15.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3435 PF11917.3 KFY03270.1 - 3.5e-67 226.9 0.0 4.1e-65 220.1 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) FA_desaturase PF00487.19 KFY03272.1 - 5.8e-09 35.7 20.7 9.3e-09 35.1 13.8 1.7 1 1 0 1 1 1 1 Fatty acid desaturase SIR2 PF02146.12 KFY03273.1 - 7.6e-17 61.6 0.0 1.4e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Sir2 family Ferric_reduct PF01794.14 KFY03274.1 - 3.6e-12 46.4 6.5 3.6e-12 46.4 4.5 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFY03274.1 - 3.1e-10 39.8 0.0 7.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFY03274.1 - 0.00016 21.6 0.0 0.00053 19.9 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Cytochrom_B561 PF03188.11 KFY03274.1 - 0.078 12.8 6.5 0.18 11.6 4.5 1.6 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF3723 PF12520.3 KFY03276.1 - 2.4e-102 343.0 0.1 2.4e-102 343.0 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3723) Reo_sigmaC PF04582.7 KFY03276.1 - 3.5 6.6 20.3 0.022 13.9 1.1 3.9 2 2 1 3 3 3 0 Reovirus sigma C capsid protein DUF3435 PF11917.3 KFY03279.1 - 8.9e-43 146.5 0.1 1.1e-42 146.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3435 PF11917.3 KFY03298.1 - 9.5e-15 54.2 0.0 9.5e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) TPR_14 PF13428.1 KFY03300.1 - 0.024 15.2 0.1 4.7 8.1 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFY03300.1 - 0.078 12.9 0.8 14 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KFY03302.1 - 4e-10 39.2 0.0 6.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03302.1 - 6e-05 22.2 0.1 0.00012 21.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Nramp PF01566.13 KFY03307.1 - 3.6e-89 299.0 16.4 5.5e-89 298.4 11.3 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Copper-fist PF00649.13 KFY03308.1 - 4.5e-09 35.3 8.1 2e-08 33.2 5.6 2.0 1 1 0 1 1 1 1 Copper fist DNA binding domain Abhydrolase_3 PF07859.8 KFY03309.1 - 1.3e-40 139.1 0.0 1.8e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFY03309.1 - 3.7e-08 32.5 0.1 7.9e-08 31.4 0.1 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFY03309.1 - 0.0038 17.0 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KFY03309.1 - 0.0039 16.5 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KFY03309.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cu-oxidase_2 PF07731.9 KFY03310.1 - 3.1e-41 140.1 2.5 1.4e-34 118.5 0.2 3.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFY03310.1 - 2.7e-36 123.8 2.3 9.2e-36 122.1 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KFY03310.1 - 2e-16 60.2 0.1 2.8e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Multicopper oxidase Ctr PF04145.10 KFY03310.1 - 1.5e-05 25.1 1.9 3.5e-05 23.8 1.3 1.7 1 0 0 1 1 1 1 Ctr copper transporter family Cu-oxidase_3 PF07732.10 KFY03313.1 - 3.5e-19 68.6 0.4 6.3e-17 61.3 0.1 2.1 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KFY03313.1 - 0.0009 19.1 0.0 0.0018 18.2 0.0 1.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFY03313.1 - 0.029 13.8 0.1 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Multicopper oxidase Ferric_reduct PF01794.14 KFY03341.1 - 9.2e-19 67.7 9.7 9.2e-19 67.7 6.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFY03341.1 - 2.7e-15 56.1 0.0 6.5e-15 54.8 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFY03341.1 - 0.033 14.1 0.1 0.075 12.9 0.1 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain HMA PF00403.21 KFY03343.1 - 5.2e-28 96.9 0.0 3.7e-11 42.9 0.0 3.4 3 0 0 3 3 3 3 Heavy-metal-associated domain GFA PF04828.9 KFY03343.1 - 0.016 15.1 0.0 1.9 8.5 0.0 3.4 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Fer2 PF00111.22 KFY03343.1 - 0.1 12.3 0.3 15 5.3 0.0 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain E1-E2_ATPase PF00122.15 KFY03343.1 - 0.12 11.4 0.1 0.26 10.2 0.0 1.6 2 0 0 2 2 2 0 E1-E2 ATPase DUF4428 PF14471.1 KFY03343.1 - 0.23 11.2 1.1 31 4.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) E1-E2_ATPase PF00122.15 KFY03349.1 - 3e-54 183.5 0.0 5.5e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY03349.1 - 5.5e-40 138.0 0.1 8.6e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFY03349.1 - 8.6e-26 89.8 0.0 3.1e-10 40.0 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 KFY03349.1 - 3.9e-15 56.5 0.0 7.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY03349.1 - 0.00036 20.2 0.0 0.0082 15.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4006 PF13179.1 KFY03349.1 - 0.48 9.9 2.0 1.2 8.7 1.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) ADAM_spacer1 PF05986.9 KFY03359.1 - 3.9e-06 26.7 4.5 1 9.2 0.0 4.5 2 2 3 5 5 5 3 ADAM-TS Spacer 1 AsmA_2 PF13502.1 KFY03359.1 - 0.0049 16.2 6.7 1 8.6 0.3 3.1 1 1 1 2 2 2 2 AsmA-like C-terminal region Bactofilin PF04519.8 KFY03359.1 - 0.011 15.7 11.8 0.23 11.4 4.0 2.8 2 1 0 2 2 2 0 Polymer-forming cytoskeletal VCBS PF13517.1 KFY03360.1 - 9.6e-30 102.7 42.2 2e-14 53.7 1.8 8.1 3 2 7 10 10 10 9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFY03360.1 - 1.4e-16 59.6 32.4 0.0014 18.2 0.6 6.9 6 0 0 6 6 6 6 FG-GAP repeat Lipase_GDSL PF00657.17 KFY03360.1 - 1.8e-14 54.1 1.3 1.8e-14 54.1 0.9 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFY03360.1 - 3e-12 47.0 0.6 7.7e-12 45.6 0.4 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KFY03360.1 - 3.8e-05 23.4 0.2 0.00013 21.8 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 KFY03360.1 - 0.029 13.8 17.5 0.57 9.6 0.0 6.1 7 1 1 8 8 8 0 Insecticide toxin TcdB middle/N-terminal region BTB PF00651.26 KFY03361.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RE_SinI PF09570.5 KFY03361.1 - 0.003 16.5 0.2 0.0066 15.4 0.1 1.5 2 0 0 2 2 2 1 SinI restriction endonuclease ASFV_J13L PF05568.6 KFY03361.1 - 0.0033 16.9 7.1 5e+02 0.0 4.9 5.1 1 1 0 1 1 1 0 African swine fever virus J13L protein zf-RING_2 PF13639.1 KFY03363.1 - 2.8e-06 27.0 10.4 6e-06 25.9 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFY03363.1 - 5.7e-05 23.1 6.4 0.00012 22.0 4.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFY03363.1 - 0.00014 21.5 5.1 0.00042 20.1 3.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MatE PF01554.13 KFY03363.1 - 0.0074 15.9 1.5 0.0074 15.9 1.0 3.3 3 0 0 3 3 3 2 MatE FANCL_C PF11793.3 KFY03363.1 - 0.017 15.0 5.5 0.046 13.6 3.8 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KFY03363.1 - 0.02 14.9 8.8 0.043 13.8 6.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 KFY03363.1 - 1.3 8.7 7.1 2.9 7.6 4.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KFY03363.1 - 1.3 8.7 6.3 1.9 8.2 2.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KFY03363.1 - 1.6 8.5 6.6 0.69 9.6 2.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 KFY03363.1 - 4 7.5 10.5 7.5 6.6 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY03363.1 - 6 6.6 8.8 11 5.8 6.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 KFY03365.1 - 1e-11 44.4 0.0 7.7e-11 41.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03365.1 - 7.7e-11 41.5 0.0 7.6e-10 38.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY03365.1 - 0.022 14.4 0.1 0.055 13.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 KFY03375.1 - 4.3e-25 87.8 1.1 1.7e-11 44.2 0.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03375.1 - 2.4e-19 68.1 1.4 0.00066 19.3 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KFY03375.1 - 3.8e-16 58.7 2.3 6.2e-07 29.4 0.1 3.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFY03375.1 - 8.8e-14 51.5 1.9 0.0031 17.9 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY03375.1 - 1e-12 46.9 0.6 0.079 13.2 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Tropomyosin_1 PF12718.2 KFY03375.1 - 0.031 14.1 2.6 0.064 13.0 1.8 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF3447 PF11929.3 KFY03375.1 - 0.034 13.9 0.1 2.2 8.1 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) DUF1192 PF06698.6 KFY03375.1 - 0.054 13.2 0.1 6.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4094 PF13334.1 KFY03375.1 - 0.14 12.5 1.8 0.38 11.1 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) bZIP_2 PF07716.10 KFY03375.1 - 0.57 10.0 3.4 3.2 7.6 0.5 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Dev_Cell_Death PF10539.4 KFY03377.1 - 0.052 13.1 0.1 0.086 12.3 0.1 1.5 1 1 0 1 1 1 0 Development and cell death domain Josephin PF02099.12 KFY03377.1 - 0.069 12.7 0.1 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Josephin F-box-like PF12937.2 KFY03412.1 - 6.8e-06 25.7 0.6 1.4e-05 24.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY03412.1 - 6.5e-05 22.4 0.4 0.00014 21.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain BDHCT PF08072.6 KFY03412.1 - 0.25 11.4 1.0 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 BDHCT (NUC031) domain Glyco_hydro_cc PF11790.3 KFY03441.1 - 1.1e-12 47.8 0.5 1.1e-12 47.8 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Zip PF02535.17 KFY03442.1 - 4.7e-46 157.2 5.3 7.4e-46 156.6 3.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3650 PF12368.3 KFY03442.1 - 0.035 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) DUF1003 PF06210.6 KFY03446.1 - 0.0099 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) Sorb PF02208.11 KFY03447.1 - 1.1 8.6 3.4 94 2.4 0.1 3.6 1 1 2 3 3 3 0 Sorbin homologous domain Cu-oxidase_2 PF07731.9 KFY03448.1 - 5.6e-35 119.8 0.6 5.6e-35 119.8 0.4 1.4 2 0 0 2 2 2 1 Multicopper oxidase Aminotran_3 PF00202.16 KFY03462.1 - 4.5e-72 242.7 0.2 8.8e-72 241.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-III DUF2096 PF09869.4 KFY03464.1 - 0.038 13.8 0.1 0.044 13.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Nsp1_C PF05064.8 KFY03464.1 - 0.039 13.5 4.8 0.052 13.1 3.2 1.3 1 1 0 1 1 1 0 Nsp1-like C-terminal region MerR-DNA-bind PF09278.6 KFY03464.1 - 0.042 14.2 1.5 0.064 13.6 1.0 1.3 1 0 0 1 1 1 0 MerR, DNA binding Ank_2 PF12796.2 KFY03473.1 - 1.2e-297 961.3 0.0 1.9e-17 63.3 0.0 19.0 1 1 22 23 23 23 23 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFY03473.1 - 8.1e-223 715.4 20.9 2.6e-10 40.1 0.0 28.3 4 3 28 32 32 32 32 Ankyrin repeats (many copies) Ank PF00023.25 KFY03473.1 - 2.2e-214 683.6 0.0 2.8e-05 23.6 0.0 35.1 35 0 0 35 35 35 35 Ankyrin repeat Ank_4 PF13637.1 KFY03473.1 - 2.5e-194 626.7 48.1 1.3e-09 38.2 0.0 29.9 1 1 34 35 35 35 34 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY03473.1 - 8.5e-156 489.9 0.0 0.0053 16.8 0.0 35.0 35 0 0 35 35 35 34 Ankyrin repeat Shigella_OspC PF06128.6 KFY03473.1 - 6e-09 35.7 0.0 28 4.0 0.0 12.3 7 5 12 20 20 20 0 Shigella flexneri OspC protein DUF1832 PF08870.6 KFY03473.1 - 0.04 13.6 0.0 15 5.3 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1832) DUF1455 PF07306.6 KFY03473.1 - 0.37 10.8 7.3 2.5e+02 1.6 0.0 8.3 13 1 1 14 14 14 0 Protein of unknown function (DUF1455) WXG100 PF06013.7 KFY03475.1 - 0.096 12.6 1.8 0.23 11.5 1.2 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG COOH-NH2_lig PF14395.1 KFY03475.1 - 0.24 10.4 1.3 0.46 9.4 0.9 1.4 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 GldM_N PF12081.3 KFY03475.1 - 0.27 10.7 15.2 0.013 15.0 3.0 2.5 1 1 1 2 2 2 0 GldM N-terminal domain Syntaxin PF00804.20 KFY03475.1 - 0.31 11.2 5.9 0.51 10.5 3.5 1.8 1 1 0 1 1 1 0 Syntaxin DUF2514 PF10721.4 KFY03475.1 - 1.4 8.5 9.6 1.4 8.6 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF3573 PF12097.3 KFY03475.1 - 1.7 7.2 4.7 2.4 6.6 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SRF-TF PF00319.13 KFY03477.1 - 0.00015 20.9 0.7 0.0003 19.9 0.0 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Senescence_reg PF04520.8 KFY03477.1 - 0.13 12.7 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Senescence regulator Ferric_reduct PF01794.14 KFY03478.1 - 1.1e-10 41.6 10.1 1.1e-10 41.6 7.0 2.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFY03478.1 - 5.2e-06 26.2 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain DUF4112 PF13430.1 KFY03478.1 - 0.0048 16.8 1.8 0.67 9.8 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4112) DUF4455 PF14643.1 KFY03480.1 - 0.014 14.0 0.2 0.019 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) SF-assemblin PF06705.6 KFY03480.1 - 0.015 14.4 0.3 0.033 13.3 0.1 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin CENP-F_leu_zip PF10473.4 KFY03480.1 - 0.025 14.4 0.2 0.025 14.4 0.1 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF489 PF04356.7 KFY03480.1 - 0.1 12.1 0.4 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF489) IncA PF04156.9 KFY03480.1 - 0.12 11.9 0.1 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 IncA protein Peptidase_C48 PF02902.14 KFY03481.1 - 1.4e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AT_hook PF02178.14 KFY03481.1 - 0.91 9.4 7.2 2.5 8.0 5.0 1.8 1 0 0 1 1 1 0 AT hook motif DUF3723 PF12520.3 KFY03482.1 - 3.5e-70 236.9 1.6 1.1e-48 166.0 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) BTB PF00651.26 KFY03482.1 - 1.6e-14 53.8 0.1 3.5e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 KFY03483.1 - 2e-05 23.8 0.0 4.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03483.1 - 7.1e-05 22.0 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Chorismate_synt PF01264.16 KFY03501.1 - 9.3e-29 99.9 0.1 1.1e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Chorismate synthase COX7C PF02935.11 KFY03502.1 - 5.2e-16 58.1 1.2 9.2e-16 57.3 0.9 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 KFY03503.1 - 3.2e-101 338.0 0.0 3.2e-101 338.0 0.0 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 KFY03503.1 - 2.8e-62 209.1 0.7 5.6e-62 208.1 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KFY03503.1 - 8.7e-22 77.3 0.0 2.1e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY03503.1 - 1.5e-05 24.7 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prp19 PF08606.6 KFY03503.1 - 0.0035 17.0 0.6 0.34 10.6 0.1 2.6 2 0 0 2 2 2 1 Prp19/Pso4-like T2SE PF00437.15 KFY03503.1 - 0.0042 16.0 0.0 0.035 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein CRAL_TRIO PF00650.15 KFY03504.1 - 8.1e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFY03504.1 - 0.028 14.5 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Herpes_BLLF1 PF05109.8 KFY03504.1 - 1.7 6.4 8.4 2.2 6.1 5.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DNA_binding_1 PF01035.15 KFY03505.1 - 1.2e-26 92.2 0.1 9.2e-26 89.4 0.0 2.0 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Glycos_transf_1 PF00534.15 KFY03506.1 - 1.7e-21 76.4 0.0 2.6e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFY03506.1 - 8.2e-10 38.9 0.0 1.7e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFY03506.1 - 0.027 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Phage_P2_GpE PF06528.7 KFY03506.1 - 0.056 12.8 1.7 1.5 8.2 0.2 2.5 2 0 0 2 2 2 0 Phage P2 GpE Herpes_pp38 PF04846.8 KFY03506.1 - 0.1 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein 60KD_IMP PF02096.15 KFY03507.1 - 1.2e-21 77.2 0.0 1.5e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Pkinase PF00069.20 KFY03508.1 - 3.4e-54 183.7 0.1 4.3e-37 127.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03508.1 - 1.8e-22 79.6 0.0 6.9e-21 74.4 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY03508.1 - 2.3e-05 23.5 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFY03508.1 - 0.00032 20.4 0.1 0.0033 17.2 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family RhgB_N PF09284.5 KFY03509.1 - 2.2e-102 341.7 8.5 2.2e-102 341.7 5.9 1.6 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KFY03509.1 - 1.5e-60 203.6 0.5 2.7e-59 199.5 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFY03509.1 - 1.7e-16 60.0 1.1 1.7e-16 60.0 0.7 2.3 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KFY03509.1 - 0.00028 20.8 1.4 0.00028 20.8 0.9 3.7 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KFY03509.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) DUF4243 PF14027.1 KFY03510.1 - 8.8e-98 327.7 1.6 1.1e-97 327.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HSP33 PF01430.14 KFY03510.1 - 0.0031 16.6 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Hsp33 protein DUF1887 PF09002.6 KFY03510.1 - 0.067 11.5 0.0 0.09 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) DUF221 PF02714.10 KFY03511.1 - 1.6e-97 326.2 14.0 1.6e-97 326.2 9.7 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFY03511.1 - 8.5e-40 135.8 1.8 8.5e-40 135.8 1.3 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFY03511.1 - 7.8e-21 73.7 0.1 1.9e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFY03511.1 - 2.9e-08 34.1 0.0 0.00014 22.3 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) RRM_5 PF13893.1 KFY03511.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFY03511.1 - 0.075 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC50_N PF15295.1 KFY03511.1 - 0.18 11.7 0.5 0.31 10.9 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Dioxygenase_C PF00775.16 KFY03512.1 - 3.1e-50 169.9 0.0 4.4e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KFY03512.1 - 5.1e-13 48.8 0.0 7.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KFY03512.1 - 0.0018 18.2 0.0 0.015 15.3 0.0 2.4 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF1684 PF07920.6 KFY03512.1 - 0.043 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) Abhydrolase_5 PF12695.2 KFY03513.1 - 1.2e-07 31.5 0.2 2.1e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KFY03513.1 - 0.00022 20.1 0.1 0.00037 19.4 0.1 1.3 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KFY03513.1 - 0.0061 15.4 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme adh_short_C2 PF13561.1 KFY03514.1 - 3.1e-33 115.5 0.0 3.6e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFY03514.1 - 1.5e-29 103.0 0.4 1.9e-29 102.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY03514.1 - 2.4e-13 50.1 0.1 3.5e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KFY03514.1 - 0.00013 21.6 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus 3HCDH_N PF02737.13 KFY03514.1 - 0.034 13.7 0.1 0.048 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KFY03514.1 - 0.11 12.2 0.8 0.16 11.8 0.5 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Zn_clus PF00172.13 KFY03515.1 - 6.8e-05 22.7 7.9 0.00016 21.5 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phospholip_B PF04916.8 KFY03515.1 - 0.013 13.6 0.0 0.019 13.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B AMP-binding PF00501.23 KFY03516.1 - 1.7e-78 263.9 0.0 2.4e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KFY03516.1 - 1.3e-74 250.8 0.0 2.7e-74 249.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KFY03516.1 - 2.5e-56 191.0 0.0 4e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KFY03516.1 - 2.1e-52 178.4 0.0 4.2e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KFY03516.1 - 1.4e-49 168.1 0.4 3.5e-49 166.9 0.1 1.9 2 0 0 2 2 1 1 KR domain Condensation PF00668.15 KFY03516.1 - 6.2e-43 146.7 0.1 1e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KFY03516.1 - 3.3e-40 137.7 0.0 2.7e-39 134.7 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFY03516.1 - 3.2e-29 101.1 0.0 7.7e-29 99.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFY03516.1 - 1.4e-23 83.1 0.0 4e-22 78.3 0.0 3.0 2 1 0 2 2 2 1 Male sterility protein Methyltransf_12 PF08242.7 KFY03516.1 - 8.3e-21 74.3 0.0 3.4e-20 72.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFY03516.1 - 6.3e-16 58.3 1.1 1.8e-07 31.3 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KFY03516.1 - 6.6e-14 51.9 0.0 1.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KFY03516.1 - 8.2e-14 51.6 0.0 2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_31 PF13847.1 KFY03516.1 - 7.1e-13 48.4 0.0 1.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY03516.1 - 1.7e-12 47.6 0.0 5.2e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY03516.1 - 2.1e-09 37.9 0.0 1.8e-08 34.9 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY03516.1 - 8e-08 32.5 0.0 7.3e-07 29.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY03516.1 - 8e-07 28.4 0.0 1.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KFY03516.1 - 2.2e-05 24.0 0.0 4.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 KFY03516.1 - 0.00016 20.8 0.1 0.00044 19.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Thiolase_N PF00108.18 KFY03516.1 - 0.00027 19.9 0.0 0.0021 17.0 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 KFY03516.1 - 0.00045 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KFY03516.1 - 0.00047 19.1 0.0 0.00098 18.0 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase 3Beta_HSD PF01073.14 KFY03516.1 - 0.0098 14.6 0.0 1.2 7.7 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 KFY03516.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 KFY03516.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_zinc_N PF00107.21 KFY03517.1 - 4.9e-07 29.3 0.0 8.8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY03517.1 - 9.8e-05 22.0 1.1 0.00034 20.3 0.1 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KFY03518.1 - 1.7e-39 135.6 0.0 2.1e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.3 KFY03519.1 - 0.00054 19.8 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Myb_DNA-bind_6 PF13921.1 KFY03527.1 - 4.2e-06 26.7 0.8 7.5e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_32 PF13565.1 KFY03527.1 - 0.09 13.5 0.5 0.23 12.2 0.4 1.7 1 1 0 1 1 1 0 Homeodomain-like domain DUF3388 PF11868.3 KFY03527.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Pkinase PF00069.20 KFY03528.1 - 4.2e-14 52.3 0.0 6e-13 48.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03528.1 - 0.0003 19.9 0.0 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF4414 PF14377.1 KFY03530.1 - 0.11 12.3 0.6 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Helicase_C PF00271.26 KFY03551.1 - 1.4e-09 37.6 0.0 2.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MoCF_biosynth PF00994.19 KFY03551.1 - 0.00028 20.3 0.0 0.00086 18.7 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain PyrI_C PF02748.10 KFY03551.1 - 2.5 7.6 5.6 3.4 7.1 0.0 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain F-box-like PF12937.2 KFY03552.1 - 7.3e-05 22.4 0.1 0.00023 20.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY03552.1 - 0.0036 16.9 0.1 0.023 14.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain DUF3663 PF12404.3 KFY03552.1 - 0.081 12.7 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Peptidase DUF489 PF04356.7 KFY03555.1 - 0.042 13.4 0.3 0.088 12.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Pkinase PF00069.20 KFY03557.1 - 2.2e-35 122.0 0.0 3.4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03557.1 - 6.1e-21 74.6 0.0 8.5e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFY03557.1 - 4.8e-07 29.0 0.0 8.4e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFY03557.1 - 4.1e-05 22.6 0.0 5.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFY03557.1 - 0.053 13.2 0.1 0.38 10.4 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFY03557.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Chon_Sulph_att PF06566.6 KFY03559.1 - 0.44 10.1 4.2 0.49 9.9 2.9 1.0 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain zf-MYND PF01753.13 KFY03562.1 - 1.4e-09 37.6 9.8 2.2e-09 36.9 6.8 1.4 1 0 0 1 1 1 1 MYND finger Ald_Xan_dh_C PF01315.17 KFY03562.1 - 0.033 14.2 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain zf-HIT PF04438.11 KFY03562.1 - 0.24 11.0 7.7 0.44 10.2 5.4 1.5 1 0 0 1 1 1 0 HIT zinc finger Ecl1 PF12855.2 KFY03562.1 - 1.4 8.2 5.4 2.9 7.2 3.7 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Pheromone PF08015.6 KFY03568.1 - 0.049 14.4 0.3 0.072 13.9 0.2 1.4 1 1 0 1 1 1 0 Fungal mating-type pheromone DUF3070 PF11270.3 KFY03568.1 - 0.084 12.6 0.7 0.19 11.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) DUF3633 PF12315.3 KFY03569.1 - 0.048 12.9 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) E1-E2_ATPase PF00122.15 KFY03576.1 - 2.3e-41 141.3 8.5 2.3e-41 141.3 5.9 1.5 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 KFY03576.1 - 4.1e-05 23.6 0.0 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 Heavy-metal-associated domain DUF4519 PF15012.1 KFY03576.1 - 0.19 11.6 0.6 0.58 10.1 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Nramp PF01566.13 KFY03578.1 - 2.3e-88 296.3 17.0 2.3e-88 296.3 11.8 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein HMA PF00403.21 KFY03579.1 - 9.3e-22 76.9 0.5 2.8e-11 43.3 0.0 4.1 4 0 0 4 4 4 3 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 KFY03579.1 - 2.7e-21 75.6 0.1 1.4e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase UbiA PF01040.13 KFY03579.1 - 0.048 12.8 1.7 0.075 12.2 1.2 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family YopX PF09643.5 KFY03579.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 YopX protein DUF4472 PF14739.1 KFY03580.1 - 0.26 11.7 5.4 0.1 13.0 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Clusterin PF01093.12 KFY03584.1 - 0.057 12.2 0.3 0.069 11.9 0.2 1.0 1 0 0 1 1 1 0 Clusterin Pox_Rap94 PF03294.9 KFY03584.1 - 0.11 10.4 0.1 0.11 10.4 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 IncA PF04156.9 KFY03584.1 - 1.6 8.2 4.3 1.9 8.0 3.0 1.2 1 0 0 1 1 1 0 IncA protein APH PF01636.18 KFY03592.1 - 4.3e-12 46.2 0.0 6.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY03592.1 - 8.3e-08 32.0 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFY03592.1 - 0.084 12.0 0.1 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Vac14_Fig4_bd PF11916.3 KFY03593.1 - 0.018 14.1 0.1 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding DUF3435 PF11917.3 KFY03611.1 - 8.6e-47 159.7 0.1 1e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Peptidase_C48 PF02902.14 KFY03625.1 - 3e-12 46.6 0.1 2.8e-11 43.4 0.1 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.14 KFY03628.1 - 7.1e-09 35.5 0.0 7.3e-08 32.3 0.0 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pyr_redox_2 PF07992.9 KFY03634.1 - 1.9e-27 96.4 0.2 2.4e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY03634.1 - 3.6e-17 62.5 1.3 6.8e-15 55.2 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY03634.1 - 1.3e-08 35.1 0.1 2.5e-05 24.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY03634.1 - 1.7e-05 24.7 0.1 0.015 15.3 0.0 3.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KFY03634.1 - 2e-05 24.8 0.0 0.0042 17.3 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 KFY03634.1 - 0.00016 20.8 0.1 0.00095 18.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFY03634.1 - 0.00043 19.3 1.8 0.68 8.7 0.0 3.2 2 2 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 KFY03634.1 - 0.011 14.6 3.5 1 8.1 0.2 3.3 3 1 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFY03634.1 - 0.019 14.0 1.0 3.3 6.6 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 KFY03634.1 - 0.022 13.6 0.1 0.4 9.5 0.0 2.7 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KFY03634.1 - 0.037 12.6 0.0 0.37 9.3 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 KFY03634.1 - 0.042 12.3 0.2 0.48 8.8 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 KFY03634.1 - 0.047 12.5 4.7 0.11 11.3 0.2 2.9 2 1 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 KFY03634.1 - 0.099 12.7 0.2 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase APH PF01636.18 KFY03638.1 - 2e-09 37.5 0.0 4.7e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY03638.1 - 4.4e-05 23.1 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ank_2 PF12796.2 KFY03638.1 - 0.016 15.4 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY03638.1 - 0.028 14.9 0.0 0.1 13.1 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF2365 PF10157.4 KFY03638.1 - 0.04 13.7 0.0 0.62 9.9 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2365) HipA_N PF07805.7 KFY03638.1 - 0.095 12.9 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 HipA-like N-terminal domain Pkinase PF00069.20 KFY03638.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Amidase PF01425.16 KFY03639.1 - 6.8e-69 232.8 1.1 1.9e-67 228.0 0.8 2.0 1 1 0 1 1 1 1 Amidase DUF2669 PF10876.3 KFY03639.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2669) Ank_2 PF12796.2 KFY03640.1 - 3.2e-30 104.3 3.4 3e-17 62.7 0.5 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03640.1 - 2.9e-26 89.9 9.2 3.6e-06 26.4 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KFY03640.1 - 6.5e-18 64.7 1.6 1.2e-05 25.7 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY03640.1 - 1e-11 43.8 4.5 0.033 14.4 0.0 6.0 6 0 0 6 6 5 4 Ankyrin repeat Ank_5 PF13857.1 KFY03640.1 - 1.2e-09 38.1 3.6 0.00086 19.4 0.2 3.8 1 1 1 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.7 KFY03640.1 - 2.1e-09 37.2 0.1 3.3e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KFY03640.1 - 0.0016 18.3 0.0 0.042 13.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY03640.1 - 0.0022 18.0 0.1 0.0085 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFY03640.1 - 0.0037 17.4 0.0 0.0097 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFY03640.1 - 0.022 13.5 0.0 0.066 12.0 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain AAA PF00004.24 KFY03640.1 - 0.035 14.3 0.0 0.09 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KFY03640.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KFY03640.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NAD_binding_6 PF08030.7 KFY03642.1 - 4.7e-11 42.8 0.0 2.7e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFY03642.1 - 8.6e-07 28.7 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFY03642.1 - 3e-06 27.3 8.7 3e-06 27.3 6.0 2.9 2 1 1 3 3 3 1 Ferric reductase like transmembrane component F-box PF00646.28 KFY03642.1 - 0.00036 20.0 0.2 0.0011 18.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY03642.1 - 0.017 14.8 1.9 0.027 14.1 0.1 2.4 2 0 0 2 2 2 0 F-box-like HECT PF00632.20 KFY03671.1 - 2.4e-90 302.9 0.0 3.4e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFY03671.1 - 8.5e-32 108.6 16.2 1.2e-10 41.0 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KFY03671.1 - 1.3e-15 56.9 0.0 3.3e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain GGDEF PF00990.16 KFY03671.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 GGDEF domain Lipase_GDSL_2 PF13472.1 KFY03672.1 - 9.8e-14 51.8 0.1 1.9e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY03672.1 - 1.3e-09 38.1 0.0 2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFY03672.1 - 0.04 13.6 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Herpes_U47 PF05467.6 KFY03673.1 - 1.6 6.4 4.2 2.3 5.9 2.9 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 APS-reductase_C PF12139.3 KFY03678.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit Alpha-amylase PF00128.19 KFY03688.1 - 2.6e-21 76.3 0.6 2.3e-17 63.3 0.3 3.0 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KFY03688.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 KFY03688.1 - 3.7e-06 26.4 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFY03688.1 - 3.1e-05 24.1 0.0 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PA26 PF04636.8 KFY03688.1 - 0.91 8.1 0.1 1.5 7.4 0.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Polysacc_deac_1 PF01522.16 KFY03689.1 - 2.4e-23 82.1 0.0 4.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Epimerase PF01370.16 KFY03689.1 - 4.2e-06 26.3 0.1 0.0094 15.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFY03689.1 - 8.4e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KFY03689.1 - 0.00039 20.7 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFY03689.1 - 0.0015 17.2 0.5 0.3 9.7 0.1 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFY03689.1 - 0.006 15.5 0.0 0.029 13.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KFY03690.1 - 3e-88 296.0 0.0 3.8e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY03690.1 - 1.2e-10 42.1 1.8 4.9e-10 40.2 0.3 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GWT1 PF06423.7 KFY03691.1 - 0.055 13.5 0.1 0.09 12.8 0.1 1.3 1 0 0 1 1 1 0 GWT1 IER PF05760.7 KFY03706.1 - 0.1 12.5 1.3 0.1 12.5 0.9 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) HAND PF09110.6 KFY03706.1 - 0.27 11.6 5.6 0.32 11.4 3.9 1.3 1 1 0 1 1 1 0 HAND Cut8_N PF14482.1 KFY03706.1 - 0.28 11.1 3.0 5.2 7.1 2.1 2.2 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Med7 PF05983.6 KFY03716.1 - 0.0072 16.1 0.3 0.0088 15.8 0.2 1.1 1 0 0 1 1 1 1 MED7 protein Paramyxo_ncap PF00973.14 KFY03716.1 - 0.06 12.0 0.9 0.059 12.0 0.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3350 PF11830.3 KFY03716.1 - 1 9.4 3.6 4.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3350) DUF3692 PF12469.3 KFY03721.1 - 0.091 12.9 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 CRISPR-associated protein BOP1NT PF08145.7 KFY03721.1 - 0.15 11.7 4.0 0.24 11.1 2.8 1.4 1 1 0 1 1 1 0 BOP1NT (NUC169) domain Cation_efflux PF01545.16 KFY03734.1 - 8.8e-15 54.5 0.1 1.1e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 Cation efflux family Hydrolase PF00702.21 KFY03735.1 - 3.4e-16 60.2 0.0 4.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY03735.1 - 3.3e-09 37.1 0.0 4.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY03735.1 - 5.3e-05 22.9 0.2 0.0056 16.2 0.1 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CENP-B_N PF04218.8 KFY03735.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain E1-E2_ATPase PF00122.15 KFY03755.1 - 3.8e-24 85.0 0.2 7e-24 84.1 0.0 1.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KFY03755.1 - 1.1e-12 47.1 0.1 1.1e-12 47.1 0.1 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF3650 PF12368.3 KFY03755.1 - 0.036 13.5 0.7 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF4131 PF13567.1 KFY03755.1 - 0.23 10.8 2.8 0.63 9.4 1.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF572 PF04502.8 KFY03756.1 - 0.32 10.1 15.5 0.71 9.0 10.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) AUX_IAA PF02309.11 KFY03756.1 - 6.2 6.5 9.0 14 5.3 6.2 1.7 1 1 0 1 1 1 0 AUX/IAA family FeS PF04060.8 KFY03769.1 - 0.0022 17.5 36.0 63 3.2 0.0 11.7 13 0 0 13 13 13 10 Putative Fe-S cluster IFP_35_N PF07334.8 KFY03769.1 - 0.28 11.1 14.6 1.5e+02 2.4 0.0 6.5 1 1 10 11 11 11 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF221 PF02714.10 KFY03784.1 - 1.8e-15 56.6 6.3 1.8e-15 56.6 4.4 1.4 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KFY03784.1 - 4e-14 52.2 0.0 5.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Phosphate metabolism protein PrgI PF12666.2 KFY03784.1 - 2.5 8.3 8.3 0.35 11.0 1.0 2.1 2 0 0 2 2 2 0 PrgI family protein FAD_binding_8 PF08022.7 KFY03785.1 - 1.4e-10 40.9 0.1 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFY03785.1 - 6.3e-08 32.6 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain zf-CCHC_5 PF14787.1 KFY03786.1 - 0.046 13.2 0.1 0.21 11.1 0.1 2.2 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CorA PF01544.13 KFY03829.1 - 2.9e-05 23.2 0.1 5.9e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein VKOR PF07884.9 KFY03829.1 - 0.0066 16.3 1.3 0.017 14.9 0.9 1.6 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Ank_2 PF12796.2 KFY03830.1 - 2.4e-148 482.8 48.9 6.9e-19 67.9 0.1 9.0 4 2 9 13 13 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03830.1 - 1.1e-92 299.5 42.8 6.4e-07 28.8 0.0 19.9 21 0 0 21 21 20 17 Ankyrin repeat Ank_4 PF13637.1 KFY03830.1 - 6.9e-78 255.7 16.3 1.4e-09 38.2 0.0 17.0 1 1 15 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY03830.1 - 5.4e-59 190.2 19.0 0.00036 20.4 0.0 18.6 18 0 0 18 18 18 14 Ankyrin repeat Ank_5 PF13857.1 KFY03830.1 - 4.7e-48 160.1 26.8 2.1e-05 24.5 0.1 12.3 6 4 4 12 12 12 10 Ankyrin repeats (many copies) NACHT PF05729.7 KFY03830.1 - 1e-11 44.8 0.0 3.2e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFY03830.1 - 0.00064 19.7 0.0 0.015 15.2 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFY03830.1 - 0.0014 18.7 0.0 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFY03830.1 - 0.003 16.9 0.0 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFY03830.1 - 0.0043 17.1 0.0 0.2 11.8 0.0 3.0 3 0 0 3 3 3 1 RNA helicase Arch_ATPase PF01637.13 KFY03830.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 KFY03830.1 - 0.071 12.0 0.0 0.32 9.9 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.1 KFY03830.1 - 0.099 12.5 0.0 2.7 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arg_repressor PF01316.16 KFY03830.1 - 2.4 7.7 13.4 16 5.1 0.0 6.8 8 0 0 8 8 6 0 Arginine repressor, DNA binding domain DUF3710 PF12502.3 KFY03830.1 - 5 6.4 9.0 15 4.8 0.0 5.3 4 2 1 5 5 5 0 Protein of unknown function (DUF3710) NPV_P10 PF05531.7 KFY03831.1 - 0.0038 17.4 0.0 0.0064 16.7 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 KFY03831.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Laminin Domain II IncA PF04156.9 KFY03831.1 - 0.043 13.4 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein HsbA PF12296.3 KFY03831.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A ADIP PF11559.3 KFY03838.1 - 0.0063 16.4 0.7 0.0099 15.7 0.5 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Spc24 PF08286.6 KFY03838.1 - 0.089 12.4 0.7 0.16 11.6 0.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1515 PF07439.6 KFY03838.1 - 0.17 11.7 0.3 0.37 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) RNase_H PF00075.19 KFY03842.1 - 1.1e-07 32.2 0.2 2.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 RNase H DUF935 PF06074.7 KFY03842.1 - 0.09 11.4 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DDE_3 PF13358.1 KFY03844.1 - 1.4e-18 67.0 0.2 2.3e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KFY03844.1 - 1.2e-06 28.4 1.5 2.9e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 Transposase HTH_IclR PF09339.5 KFY03844.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.7 KFY03844.1 - 0.0013 18.1 0.2 0.0048 16.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 KFY03844.1 - 0.013 15.1 0.1 0.1 12.2 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.1 KFY03844.1 - 0.027 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 KFY03844.1 - 0.039 13.4 0.1 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 KFY03844.1 - 0.088 12.1 1.7 0.32 10.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 zf-C3HC4 PF00097.20 KFY03844.1 - 0.12 12.0 0.8 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TetR_N PF00440.18 KFY03844.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Zn_Tnp_IS1595 PF12760.2 KFY03844.1 - 0.21 11.4 2.5 0.32 10.8 0.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain MerR PF00376.18 KFY03844.1 - 4.3 6.9 8.5 1.8 8.1 0.0 3.9 5 0 0 5 5 5 0 MerR family regulatory protein 4HBT PF03061.17 KFY03866.1 - 5e-07 29.7 0.0 9.7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily SUR7 PF06687.7 KFY03867.1 - 1.3e-25 90.2 16.6 1.5e-25 90.0 11.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Pex14_N PF04695.8 KFY03868.1 - 0.15 12.1 0.2 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2236 PF09995.4 KFY03869.1 - 9.7e-41 139.6 0.0 1.2e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) VirE_N PF08800.5 KFY03869.1 - 0.13 12.0 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 VirE N-terminal domain DUF4509 PF14970.1 KFY03872.1 - 0.099 12.2 0.9 0.13 11.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Bacillus_HBL PF05791.6 KFY03872.1 - 0.14 11.5 2.2 0.2 11.0 1.6 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) MFS_1 PF07690.11 KFY03873.1 - 4.9e-42 143.8 58.5 3.9e-31 108.0 23.3 3.4 2 2 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY03873.1 - 9.4e-14 50.5 25.9 1.9e-13 49.5 18.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY03873.1 - 2.1e-11 43.1 10.5 2.1e-11 43.1 7.3 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 KFY03873.1 - 7.4 6.4 13.8 1.2 8.9 0.4 3.8 4 0 0 4 4 4 0 MFS_1 like family UPF0060 PF02694.10 KFY03893.1 - 0.00011 22.1 1.8 0.00018 21.5 1.3 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family TcpE PF12648.2 KFY03893.1 - 0.11 12.6 2.0 0.18 11.9 1.4 1.4 1 0 0 1 1 1 0 TcpE family Arteri_Gl PF00951.13 KFY03893.1 - 0.83 9.2 7.3 1.3 8.5 5.1 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Pkinase PF00069.20 KFY03895.1 - 0.00022 20.4 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain NPV_P10 PF05531.7 KFY03895.1 - 0.067 13.4 1.0 0.15 12.2 0.7 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Tektin PF03148.9 KFY03896.1 - 0.0003 19.4 0.9 0.0004 19.0 0.7 1.1 1 0 0 1 1 1 1 Tektin family DUF2051 PF09738.4 KFY03896.1 - 0.00033 20.0 0.1 0.00043 19.6 0.1 1.1 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) ERM PF00769.14 KFY03896.1 - 0.0035 16.9 0.1 0.0035 16.9 0.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF4515 PF14988.1 KFY03896.1 - 0.013 15.1 2.0 0.019 14.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) PhoU PF01895.14 KFY03896.1 - 0.013 15.8 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 PhoU domain DUF3584 PF12128.3 KFY03896.1 - 0.013 12.8 2.0 0.016 12.6 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 KFY03896.1 - 0.016 14.1 1.1 0.022 13.7 0.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2383 PF09537.5 KFY03896.1 - 0.017 15.3 0.8 0.038 14.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Filament PF00038.16 KFY03896.1 - 0.018 14.5 3.6 0.023 14.1 2.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFY03896.1 - 0.019 14.7 2.3 0.032 13.9 1.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 KFY03896.1 - 0.028 12.8 0.7 0.035 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 KFY03896.1 - 0.032 13.2 0.5 0.042 12.8 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 KFY03896.1 - 0.032 13.9 4.7 0.064 12.9 1.6 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 KFY03896.1 - 0.034 14.1 1.3 0.083 12.8 0.2 2.0 2 0 0 2 2 2 0 bZIP transcription factor TBPIP PF07106.8 KFY03896.1 - 0.037 13.5 1.0 0.067 12.7 0.7 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tup_N PF08581.5 KFY03896.1 - 0.047 13.8 1.4 0.095 12.9 0.2 2.0 1 1 1 2 2 2 0 Tup N-terminal Mnd1 PF03962.10 KFY03896.1 - 0.055 13.1 1.0 0.083 12.5 0.7 1.3 1 0 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 KFY03896.1 - 0.078 13.2 3.4 0.11 12.7 1.4 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF904) MbeD_MobD PF04899.7 KFY03896.1 - 0.079 12.8 0.1 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 MbeD/MobD like SlyX PF04102.7 KFY03896.1 - 0.082 13.2 2.9 7.8 6.9 0.7 3.1 2 1 1 3 3 3 0 SlyX Spectrin PF00435.16 KFY03896.1 - 0.089 13.0 1.9 4.1 7.7 0.0 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF641 PF04859.7 KFY03896.1 - 0.094 12.4 0.4 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 KFY03896.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 KFY03896.1 - 0.15 11.5 6.0 0.086 12.3 2.2 1.9 1 1 1 2 2 2 0 Septum formation initiator FlxA PF14282.1 KFY03896.1 - 0.17 11.8 1.5 0.36 10.7 1.1 1.5 1 0 0 1 1 1 0 FlxA-like protein Cep57_CLD PF14073.1 KFY03896.1 - 0.2 11.4 4.0 2.7 7.7 2.8 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 Spc7 PF08317.6 KFY03896.1 - 0.2 10.2 3.6 0.12 11.0 0.9 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Rab5-bind PF09311.6 KFY03896.1 - 0.23 11.3 6.3 0.4 10.5 3.6 1.9 2 1 0 2 2 2 0 Rabaptin-like protein IncA PF04156.9 KFY03896.1 - 0.35 10.4 6.3 1.1 8.8 4.5 1.5 1 1 0 1 1 1 0 IncA protein DUF4200 PF13863.1 KFY03896.1 - 0.41 10.6 4.6 3.4 7.6 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) YlqD PF11068.3 KFY03896.1 - 0.44 10.5 3.5 1.1 9.3 2.0 1.7 1 1 2 3 3 3 0 YlqD protein Prefoldin_2 PF01920.15 KFY03896.1 - 0.73 9.6 5.2 4.8 7.0 1.6 2.2 1 1 1 2 2 2 0 Prefoldin subunit ADIP PF11559.3 KFY03896.1 - 0.89 9.4 5.7 1.2 9.0 1.6 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 KFY03896.1 - 0.92 9.3 4.6 2.1 8.2 3.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper DUF2968 PF11180.3 KFY03896.1 - 1.4 8.2 6.4 1.2 8.5 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF904 PF06005.7 KFY03897.1 - 0.031 14.5 1.3 0.27 11.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) WXG100 PF06013.7 KFY03897.1 - 0.061 13.3 0.0 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG AAA_22 PF13401.1 KFY03898.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Patatin PF01734.17 KFY03899.1 - 7.7e-21 74.9 0.2 1.5e-20 74.0 0.2 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.1 KFY03899.1 - 0.0012 18.5 9.5 0.0028 17.3 6.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFY03899.1 - 0.056 13.4 11.3 0.15 12.1 7.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY03899.1 - 0.33 10.8 10.6 0.73 9.7 7.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KFY03899.1 - 0.89 9.2 9.2 2.3 7.9 6.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF221 PF02714.10 KFY03900.1 - 2.8e-97 325.4 28.1 2.8e-97 325.4 19.5 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFY03900.1 - 3.1e-41 140.5 1.2 3.1e-41 140.5 0.8 3.4 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFY03900.1 - 4e-12 45.8 0.0 1.7e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KFY03900.1 - 6.2e-09 36.2 5.2 0.00039 20.8 0.5 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) TPR_10 PF13374.1 KFY03913.1 - 1.1e-13 50.5 0.0 7.6e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY03913.1 - 1.1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03913.1 - 0.14 12.0 0.0 0.63 9.9 0.0 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFY03914.1 - 2.9e-85 280.7 20.0 2.2e-21 76.0 0.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03914.1 - 8.2e-58 189.4 15.9 2.5e-09 36.4 0.1 8.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFY03914.1 - 2.7e-44 148.7 13.4 1e-08 35.4 0.1 6.2 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY03914.1 - 1.1e-39 130.4 10.3 4.1e-07 29.6 0.1 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KFY03914.1 - 4.1e-36 122.1 15.2 6.3e-08 32.6 0.3 7.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFY03914.1 - 0.17 11.3 0.2 17 4.7 0.0 2.8 3 0 0 3 3 3 0 Shigella flexneri OspC protein gag-asp_proteas PF13975.1 KFY03914.1 - 0.22 11.3 1.1 7.1 6.5 0.0 3.3 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease DDHD PF02862.12 KFY03915.1 - 0.032 14.0 2.2 1.8 8.2 0.8 2.2 2 0 0 2 2 2 0 DDHD domain Transketolase_N PF00456.16 KFY03915.1 - 0.091 11.5 1.6 0.12 11.1 1.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF4355 PF14265.1 KFY03915.1 - 0.47 10.4 13.4 0.85 9.5 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF221 PF02714.10 KFY03916.1 - 2.3e-97 325.7 26.6 2.3e-97 325.7 18.4 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFY03916.1 - 3.9e-41 140.2 1.6 3.9e-41 140.2 1.1 3.6 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFY03916.1 - 5.2e-12 45.4 0.0 2.1e-11 43.5 0.0 2.1 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFY03916.1 - 9.6e-09 35.6 9.1 0.00051 20.5 0.2 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) DUF2180 PF09947.4 KFY03916.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) Helicase_C PF00271.26 KFY03918.1 - 0.00056 19.7 0.0 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFY03918.1 - 0.0049 16.3 0.2 0.0085 15.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Integrin_b_cyt PF08725.6 KFY03918.1 - 0.02 14.2 0.0 4 6.9 0.0 2.6 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain DUF2058 PF09831.4 KFY03918.1 - 0.4 10.5 1.9 2 8.2 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Vac14_Fig4_bd PF11916.3 KFY03923.1 - 0.024 13.8 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fig4_bd PF11916.3 KFY03928.1 - 0.012 14.7 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding F-box PF00646.28 KFY03931.1 - 2.7e-06 26.8 0.4 5.9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY03931.1 - 0.016 14.9 0.3 0.038 13.7 0.2 1.6 1 0 0 1 1 1 0 F-box-like APH PF01636.18 KFY03932.1 - 1e-06 28.7 0.1 0.00017 21.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFY03932.1 - 1.5e-06 27.4 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFY03932.1 - 0.00018 20.7 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KFY03932.1 - 0.00056 19.3 0.0 0.00094 18.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KFY03932.1 - 0.00065 19.3 0.0 0.26 10.8 0.0 2.3 1 1 1 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.6 KFY03932.1 - 0.0007 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_C48 PF02902.14 KFY03939.1 - 3.5e-06 26.7 0.0 4.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain BTB PF00651.26 KFY03940.1 - 3.2e-18 65.7 0.1 6.8e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3723 PF12520.3 KFY03941.1 - 7.6e-71 239.1 0.2 1.1e-70 238.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) HTH_psq PF05225.11 KFY03972.1 - 7.5e-07 28.6 0.3 1e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 KFY03972.1 - 0.04 13.9 0.2 0.087 12.8 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_31 PF13560.1 KFY03972.1 - 0.063 13.4 0.8 0.12 12.5 0.5 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_8 PF02954.14 KFY03972.1 - 0.09 12.3 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family LacI PF00356.16 KFY03972.1 - 0.097 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family PIG-L PF02585.12 KFY03973.1 - 8.2e-10 39.2 0.0 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.10 KFY03973.1 - 1.3e-09 38.4 0.0 3.5e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif rve PF00665.21 KFY03974.1 - 1.3e-19 70.4 0.0 2.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 KFY03974.1 - 0.052 12.9 0.1 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Trypan_PARP PF05887.6 KFY03974.1 - 0.13 12.1 8.0 2.4 7.9 1.4 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PAD_porph PF04371.10 KFY03975.1 - 2.9e-97 325.6 0.0 3.2e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Toxin_2 PF00451.14 KFY03976.1 - 0.092 12.8 1.2 6.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 OTT_1508_deam PF14441.1 KFY03977.1 - 5e-19 68.5 0.0 1.2e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase F-box-like PF12937.2 KFY03977.1 - 0.00017 21.2 0.6 0.00044 19.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY03977.1 - 0.00042 19.9 5.3 0.0028 17.2 0.1 2.9 3 0 0 3 3 3 2 F-box domain DUF3648 PF12364.3 KFY03977.1 - 0.58 10.1 3.0 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3648) APH PF01636.18 KFY03990.1 - 3.6e-07 30.1 0.2 0.0018 18.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFY03990.1 - 1.9e-06 27.1 0.1 9.2e-06 24.8 0.0 2.0 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFY03990.1 - 3.3e-06 26.5 0.0 5.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KFY03990.1 - 0.00045 19.4 0.0 0.00073 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KFY03990.1 - 0.0018 17.5 0.2 0.0026 16.9 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KFY03990.1 - 0.11 12.0 0.1 0.35 10.3 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Nuc_sug_transp PF04142.10 KFY04007.1 - 2e-69 233.3 10.9 2.8e-69 232.9 7.5 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KFY04007.1 - 1.3e-07 31.8 4.3 1.3e-07 31.8 3.0 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFY04007.1 - 3.4e-06 27.1 9.4 3.4e-06 27.1 6.5 3.2 2 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 KFY04007.1 - 3.8e-06 26.6 25.9 3.5e-05 23.4 3.8 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KFY04007.1 - 0.0018 17.2 4.0 0.0018 17.2 2.8 2.2 2 0 0 2 2 2 1 UAA transporter family APH PF01636.18 KFY04010.1 - 1.2e-10 41.5 0.3 5e-10 39.5 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY04010.1 - 2.4e-06 27.3 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KFY04010.1 - 0.03 13.4 0.0 3.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF772 PF05598.6 KFY04018.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Transposase domain (DUF772) Epimerase PF01370.16 KFY04028.1 - 7.8e-14 51.6 0.1 8.4e-13 48.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY04028.1 - 1.2e-09 38.4 0.3 1.2e-09 38.4 0.2 1.5 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KFY04028.1 - 3.6e-09 36.2 1.5 4.7e-09 35.8 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 KFY04028.1 - 2.8e-06 26.4 0.0 8.2e-06 24.9 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KFY04028.1 - 3.8e-05 22.5 0.1 0.0011 17.6 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFY04028.1 - 0.0025 18.0 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFY04028.1 - 0.0087 15.0 0.2 0.016 14.1 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase adh_short PF00106.20 KFY04028.1 - 0.03 14.2 0.6 0.075 12.9 0.0 1.8 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFY04028.1 - 0.051 12.4 0.1 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 KFY04028.1 - 0.11 12.3 0.2 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans_2 PF11951.3 KFY04029.1 - 2.5e-06 26.3 0.4 0.00014 20.6 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 KFY04030.1 - 5.5e-30 104.2 73.6 3.1e-26 91.9 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferritin_2 PF13668.1 KFY04032.1 - 4.8e-45 152.8 3.3 8.8e-45 152.0 2.3 1.4 1 0 0 1 1 1 1 Ferritin-like domain DUF1180 PF06679.7 KFY04033.1 - 0.12 12.2 4.3 0.14 12.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1517 PF07466.6 KFY04033.1 - 1.4 7.8 4.3 1.8 7.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TPR_10 PF13374.1 KFY04034.1 - 4.3e-42 140.8 0.9 1.9e-13 49.8 0.0 3.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFY04034.1 - 1.1e-33 114.9 0.6 5.9e-17 61.3 0.5 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY04034.1 - 3.1e-19 68.3 2.3 9.5e-09 34.7 0.2 2.7 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFY04034.1 - 2.5e-17 61.6 1.1 8.3e-05 22.0 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY04034.1 - 6.5e-16 56.8 0.9 1.6e-05 24.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY04034.1 - 5.5e-14 50.7 1.3 0.0004 19.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFY04034.1 - 1e-13 51.5 0.0 3.6e-09 37.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFY04034.1 - 1.3e-09 37.4 0.3 0.071 13.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFY04034.1 - 2.4e-09 36.2 2.0 0.0063 16.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 KFY04034.1 - 6.2e-09 35.4 1.1 0.016 14.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFY04034.1 - 3.2e-07 30.3 1.1 0.33 11.7 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFY04034.1 - 2.8e-06 27.3 0.1 0.00021 21.3 0.0 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFY04034.1 - 3.3e-06 27.2 0.7 1.2 9.7 0.0 4.5 5 1 0 5 5 3 2 Tetratricopeptide repeat MIT PF04212.13 KFY04034.1 - 4.8e-06 26.3 1.6 0.26 11.2 0.1 3.2 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 KFY04034.1 - 8.1e-06 26.0 4.1 0.0006 20.0 0.8 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat Rab5-bind PF09311.6 KFY04034.1 - 1e-05 25.4 1.8 0.007 16.2 0.1 2.1 1 1 1 2 2 2 2 Rabaptin-like protein TPR_4 PF07721.9 KFY04034.1 - 1.3e-05 25.1 0.0 2.8 8.6 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat 14-3-3 PF00244.15 KFY04034.1 - 0.0019 17.3 0.1 0.0054 15.8 0.0 1.6 1 1 1 2 2 2 1 14-3-3 protein PPR PF01535.15 KFY04034.1 - 0.0044 16.9 0.0 3.7 7.7 0.0 3.0 3 0 0 3 3 3 1 PPR repeat SHNi-TPR PF10516.4 KFY04034.1 - 0.01 15.0 2.7 3.7 6.8 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR 4HB_MCP_1 PF12729.2 KFY04034.1 - 0.011 15.0 1.2 1.9 7.8 0.1 2.9 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction DUF1925 PF09094.6 KFY04034.1 - 0.015 15.2 0.3 6.2 6.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1925) FTCD PF02971.9 KFY04034.1 - 0.017 14.7 0.0 3 7.4 0.0 2.3 1 1 1 2 2 2 0 Formiminotransferase domain DUF4398 PF14346.1 KFY04034.1 - 0.022 14.8 0.2 4.5 7.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) DUF4404 PF14357.1 KFY04034.1 - 0.058 13.8 2.0 1.2 9.5 0.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) DUF2664 PF10867.3 KFY04034.1 - 0.099 13.2 1.7 38 5.0 0.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2664) FliT PF05400.8 KFY04034.1 - 0.21 11.9 3.0 10 6.5 0.0 3.0 1 1 2 3 3 3 0 Flagellar protein FliT Dor1 PF04124.7 KFY04034.1 - 0.22 9.9 1.5 1.5 7.2 0.1 2.4 1 1 1 2 2 2 0 Dor1-like family Peptidase_C65 PF10275.4 KFY04040.1 - 4.2e-60 203.1 0.0 5.6e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain SPX PF03105.14 KFY04041.1 - 0.041 13.6 3.9 0.059 13.1 2.7 1.1 1 0 0 1 1 1 0 SPX domain DUF2796 PF10986.3 KFY04041.1 - 0.054 13.4 1.5 0.082 12.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Velvet PF11754.3 KFY04041.1 - 0.067 12.7 0.7 0.15 11.6 0.5 1.7 1 1 0 1 1 1 0 Velvet factor NAD_binding_6 PF08030.7 KFY04042.1 - 1.1e-15 57.8 0.0 2.5e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFY04042.1 - 1.3e-10 41.1 0.0 0.00023 20.9 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 KFY04042.1 - 6.2e-10 39.2 2.4 6.2e-10 39.2 1.7 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KFY04042.1 - 1.7e-05 25.3 0.2 0.057 13.9 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain KGG PF10685.4 KFY04042.1 - 0.21 11.5 0.5 0.52 10.3 0.3 1.6 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif FTR1 PF03239.9 KFY04043.1 - 3.1e-88 295.6 8.8 3.6e-88 295.4 6.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3169 PF11368.3 KFY04043.1 - 0.00029 20.1 0.7 0.00072 18.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) Cytochrom_B_N PF00033.14 KFY04043.1 - 0.0028 17.0 0.8 0.0028 17.0 0.5 2.0 1 1 1 2 2 2 1 Cytochrome b(N-terminal)/b6/petB XK-related PF09815.4 KFY04043.1 - 0.087 11.8 2.1 0.09 11.7 0.0 2.0 2 0 0 2 2 2 0 XK-related protein DUF331 PF03889.8 KFY04043.1 - 0.1 11.8 1.1 0.22 10.8 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF3632 PF12311.3 KFY04043.1 - 0.11 12.2 0.3 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Cu-oxidase_3 PF07732.10 KFY04044.1 - 1e-39 134.9 4.2 5.3e-37 126.1 1.9 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFY04044.1 - 2.1e-39 134.1 9.5 8e-38 129.0 0.5 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KFY04044.1 - 5.9e-35 120.5 0.7 2.8e-33 115.0 0.1 2.7 2 0 0 2 2 2 1 Multicopper oxidase Ank_2 PF12796.2 KFY04044.1 - 1.7e-26 92.3 0.0 1.2e-14 54.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04044.1 - 1.1e-22 78.6 0.0 8.7e-07 28.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KFY04044.1 - 1.2e-14 52.9 0.0 2e-05 24.3 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFY04044.1 - 2.8e-13 49.9 0.0 2.6e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04044.1 - 4.3e-10 39.4 0.0 3.8e-05 23.7 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Fungal_trans PF04082.13 KFY04044.1 - 5.5e-08 32.0 1.0 7.5e-08 31.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04044.1 - 8.4e-07 28.7 9.5 1.8e-06 27.7 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupredoxin_1 PF13473.1 KFY04044.1 - 0.026 14.3 0.0 20 5.1 0.0 3.5 3 0 0 3 3 3 0 Cupredoxin-like domain UBA PF00627.26 KFY04044.1 - 1.9 8.4 4.1 5.5 6.9 0.0 3.6 5 0 0 5 5 5 0 UBA/TS-N domain Fungal_trans PF04082.13 KFY04053.1 - 5.7e-29 100.7 0.3 7.3e-29 100.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain C1_2 PF03107.11 KFY04053.1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.6 2 1 0 2 2 2 0 C1 domain TF_Zn_Ribbon PF08271.7 KFY04053.1 - 0.99 8.7 4.1 1.3 8.4 0.9 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 KFY04053.1 - 1.1 8.8 4.0 9.3 5.8 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain adh_short_C2 PF13561.1 KFY04054.1 - 9.4e-20 71.4 0.2 6.7e-19 68.6 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFY04054.1 - 1.3e-17 64.2 4.5 3.9e-17 62.6 3.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY04054.1 - 2.4e-10 40.3 0.8 4.4e-10 39.5 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 KFY04054.1 - 0.00061 19.9 0.1 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding DUF1776 PF08643.5 KFY04054.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 KFY04054.1 - 0.0063 15.4 0.1 0.0085 15.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 KFY04054.1 - 0.0068 15.9 0.6 0.023 14.2 0.4 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.14 KFY04054.1 - 0.013 14.2 0.1 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HTHP PF11534.3 KFY04054.1 - 0.024 14.7 0.2 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) DUF1537 PF07005.6 KFY04054.1 - 0.066 12.8 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF1537 DUF1996 PF09362.5 KFY04057.1 - 4.4e-76 255.6 1.9 7.7e-76 254.8 1.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 KFY04057.1 - 1.3e-07 31.0 2.4 1.3e-07 31.0 1.7 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Lys PF00062.15 KFY04057.1 - 0.09 12.7 0.1 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Hemerythrin PF01814.18 KFY04058.1 - 6.8e-08 32.7 0.2 1.1e-07 32.1 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Peptidase_C65 PF10275.4 KFY04059.1 - 1.1e-60 205.0 0.0 1.5e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain SAM_1 PF00536.25 KFY04060.1 - 0.0066 16.5 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Response_reg PF00072.19 KFY04061.1 - 1e-24 86.6 0.5 4.3e-24 84.6 0.3 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 KFY04061.1 - 2.2e-24 85.3 0.1 5.9e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 KFY04061.1 - 2.2e-22 79.3 0.0 6.4e-16 58.6 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 KFY04061.1 - 5.8e-19 67.9 0.0 1.2e-09 37.9 0.0 2.8 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KFY04061.1 - 9e-16 57.6 0.2 2.4e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 KFY04061.1 - 2.4e-12 46.8 0.0 2.7e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold Methyltransf_11 PF08241.7 KFY04061.1 - 0.014 15.8 0.1 34 5.0 0.0 3.5 1 1 2 3 3 3 0 Methyltransferase domain Gemin7 PF11095.3 KFY04061.1 - 0.065 12.9 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7)