# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- YadA_head PF05658.9 EME76742.1 - 0.17 12.2 1.5 4.1 7.8 0.1 3.2 3 1 0 3 3 3 0 Head domain of trimeric autotransporter adhesin YL1 PF05764.8 EME76746.1 - 0.32 10.5 6.2 0.99 8.9 4.3 1.8 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.8 EME76746.1 - 1.2 8.7 7.5 3 7.3 5.2 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EME76746.1 - 2.2 8.6 14.4 0.031 14.5 3.5 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 EME76747.1 - 0.87 8.1 6.8 1.2 7.6 4.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 eIF3_subunit PF08597.5 EME76747.1 - 5.3 6.5 12.0 9.5 5.7 8.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pentapeptide PF00805.17 EME76748.1 - 3.2e-11 42.1 0.0 5.4e-08 31.9 0.1 2.7 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EME76748.1 - 2.2e-06 27.3 1.5 1.4e-05 24.7 1.3 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EME76748.1 - 0.00017 21.3 12.3 0.01 15.7 5.2 2.4 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) DUF950 PF06106.6 EME76748.1 - 0.65 10.1 4.2 5 7.2 0.3 2.4 1 1 1 2 2 2 0 Staphylococcus protein of unknown function (DUF950) DUF3796 PF12676.2 EME76757.1 - 6.7 6.9 8.3 11 6.3 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Rootletin PF15035.1 EME76758.1 - 0.19 11.6 18.4 0.69 9.8 8.2 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF2353 PF09789.4 EME76758.1 - 0.21 10.7 19.2 0.29 10.3 7.6 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) ATPase_gene1 PF09527.5 EME76758.1 - 1.4 8.7 2.5 2.2 8.1 1.7 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) GAS PF13851.1 EME76758.1 - 2.1 7.4 21.2 0.8 8.8 8.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Borrelia_P83 PF05262.6 EME76758.1 - 3.1 5.9 16.1 4.7 5.3 11.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Fib_alpha PF08702.5 EME76758.1 - 7.4 6.6 11.8 25 4.9 4.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CDC45 PF02724.9 EME76761.1 - 0.04 11.9 0.0 0.054 11.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein LRS4 PF10422.4 EME76764.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF3135 PF11333.3 EME76767.1 - 0.1 12.7 0.0 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) CDC45 PF02724.9 EME76771.1 - 2.5e-08 32.4 6.1 3.2e-08 32.0 4.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Spore_coat_CotO PF14153.1 EME76771.1 - 4.7e-06 26.1 7.4 4.7e-06 26.1 5.1 1.5 2 0 0 2 2 1 1 Spore coat protein CotO Ycf1 PF05758.7 EME76771.1 - 4.5e-05 21.4 1.5 5.3e-05 21.1 1.0 1.1 1 0 0 1 1 1 1 Ycf1 BUD22 PF09073.5 EME76771.1 - 0.0011 18.1 23.8 0.0011 18.1 16.5 1.6 2 0 0 2 2 2 1 BUD22 Cwf_Cwc_15 PF04889.7 EME76771.1 - 0.0079 15.9 20.1 0.0079 15.9 13.9 1.9 2 0 0 2 2 1 1 Cwf15/Cwc15 cell cycle control protein Mpp10 PF04006.7 EME76771.1 - 0.011 14.2 34.1 0.015 13.6 23.6 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EME76771.1 - 0.02 12.8 42.6 0.032 12.1 29.5 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 EME76771.1 - 0.033 12.8 9.2 0.056 12.0 6.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 EME76771.1 - 0.16 9.5 3.9 0.26 8.9 2.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoIIIAH PF12685.2 EME76771.1 - 0.19 11.2 14.3 0.39 10.1 9.9 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2146 PF10220.4 EME76771.1 - 0.31 8.9 5.3 0.54 8.1 3.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) YqfQ PF14181.1 EME76771.1 - 0.85 9.6 19.5 0.15 12.0 8.9 2.3 2 0 0 2 2 2 0 YqfQ-like protein Tim54 PF11711.3 EME76771.1 - 1.3 7.5 14.7 0.11 11.0 6.3 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 EME76771.1 - 2.6 6.9 12.0 0.12 11.3 4.0 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter CENP-T PF15511.1 EME76771.1 - 3.5 6.7 29.2 0.016 14.4 12.8 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 EME76771.1 - 5.1 6.4 36.3 0.045 13.1 19.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EME76771.1 - 5.4 6.2 41.9 9.3 5.4 29.0 1.3 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.1 EME76771.1 - 5.6 6.6 25.6 1.5e+04 -6.0 17.8 2.6 1 1 0 1 1 0 0 FAM176 family Astro_capsid PF03115.9 EME76771.1 - 6 4.9 14.7 8.7 4.4 10.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2722 PF10846.3 EME76771.1 - 7 5.5 20.8 0.62 9.0 6.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4248 PF14053.1 EME76772.1 - 0.0028 17.2 0.1 0.0072 15.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) 4HBT_3 PF13622.1 EME76772.1 - 2.7 7.6 11.9 8.1 6.1 7.0 2.2 1 1 0 1 1 1 0 Thioesterase-like superfamily Pkinase PF00069.20 EME76773.1 - 1.1e-22 80.4 0.0 1.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME76773.1 - 4.5e-06 25.9 0.0 6.2e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EME76773.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 FHA domain DUF1062 PF06353.7 EME76775.1 - 0.06 13.5 0.1 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) Med13_N PF11597.3 EME76775.1 - 0.11 11.1 2.1 0.14 10.8 1.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Na_sulph_symp PF00939.14 EME76777.1 - 0.025 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region DUF2681 PF10883.3 EME76792.1 - 0.078 13.1 0.3 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CENP-B_dimeris PF09026.5 EME76793.1 - 0.19 12.0 12.9 1.6 8.9 5.7 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RE_BstXI PF09552.5 EME76797.1 - 0.15 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 BstXI restriction endonuclease Sensor PF13796.1 EME76798.1 - 0.16 11.5 2.6 0.11 12.0 0.2 2.0 2 0 0 2 2 2 0 Putative sensor Adaptin_binding PF10199.4 EME76799.1 - 4 7.7 13.2 7.8 6.7 9.1 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 V_ATPase_I PF01496.14 EME76800.1 - 0.16 9.7 1.3 0.23 9.2 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Metallothio_Pro PF02069.11 EME76801.1 - 5 7.0 10.4 3.3 7.6 1.6 2.9 2 0 0 2 2 2 0 Prokaryotic metallothionein COQ9 PF08511.6 EME76807.1 - 0.0043 16.5 0.0 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 COQ9 MxiM PF11441.3 EME76816.1 - 0.11 12.5 0.3 0.18 11.9 0.1 1.4 1 1 0 1 1 1 0 Pilot protein MxiM Gly-rich_Ago1 PF12764.2 EME76816.1 - 0.21 12.2 3.1 0.17 12.5 1.3 1.6 1 1 1 2 2 2 0 Glycine-rich region of argonaut rve PF00665.21 EME76818.1 - 0.016 15.2 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain JmjC PF02373.17 EME76819.1 - 0.00029 21.0 0.4 0.0027 17.9 0.1 2.7 1 1 1 2 2 2 1 JmjC domain, hydroxylase Cnd1_N PF12922.2 EME76821.1 - 0.26 10.9 1.0 0.51 9.9 0.7 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term GRP PF07172.6 EME76821.1 - 1 9.8 24.7 0.67 10.4 15.6 1.8 1 1 1 2 2 2 0 Glycine rich protein family U79_P34 PF03064.11 EME76821.1 - 2.6 7.4 14.2 4.8 6.6 9.7 1.5 1 1 0 1 1 1 0 HSV U79 / HCMV P34 SAP PF02037.22 EME76822.1 - 0.045 13.2 0.1 0.091 12.2 0.1 1.6 1 0 0 1 1 1 0 SAP domain TMEM171 PF15471.1 EME76824.1 - 0.017 13.9 0.1 0.033 12.9 0.0 1.4 2 0 0 2 2 2 0 Transmembrane protein family 171 GBP_repeat PF02526.9 EME76828.1 - 0.029 13.7 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycophorin-binding protein NAP PF00956.13 EME76829.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) PI3K_p85B PF02192.11 EME76833.1 - 0.014 14.8 0.3 26 4.3 0.0 3.1 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain NDUF_B7 PF05676.8 EME76833.1 - 0.059 12.7 1.4 10 5.6 0.0 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) RVT_1 PF00078.22 EME76838.1 - 0.0035 16.7 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EME76839.1 - 0.00068 19.0 0.0 0.00075 18.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CFEM PF05730.6 EME76840.1 - 0.0067 16.2 6.6 0.038 13.8 4.5 2.2 1 1 0 1 1 1 1 CFEM domain SMC_Nse1 PF07574.8 EME76841.1 - 3.5e-32 111.6 0.0 4.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EME76841.1 - 1e-10 41.4 9.9 1.8e-10 40.6 6.8 1.5 1 0 0 1 1 1 1 RING-like domain zf-Apc11 PF12861.2 EME76841.1 - 6.4e-06 25.9 1.0 0.00021 21.0 1.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EME76841.1 - 0.0016 18.2 8.2 0.0031 17.3 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain HTH_IclR PF09339.5 EME76841.1 - 0.0038 16.7 0.0 0.008 15.7 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain zf-rbx1 PF12678.2 EME76841.1 - 0.029 14.4 2.4 0.26 11.4 2.4 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger FANCL_C PF11793.3 EME76841.1 - 0.088 12.7 3.3 0.29 11.1 2.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3825 PF12873.2 EME76841.1 - 0.092 11.8 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) C1_1 PF00130.17 EME76841.1 - 0.54 10.0 8.7 0.042 13.5 2.0 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 EME76841.1 - 2.1 8.0 7.3 4.6 6.9 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MAPEG PF01124.13 EME76842.1 - 4.2e-14 52.2 0.8 4.6e-14 52.1 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Ribosomal_S9 PF00380.14 EME76843.1 - 7.5e-40 135.9 0.3 8.5e-40 135.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RCC1 PF00415.13 EME76844.1 - 2.4e-29 101.2 17.3 8.1e-11 41.9 0.2 6.2 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME76844.1 - 8.7e-25 85.7 19.3 5.2e-07 29.1 0.3 5.9 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat DUF995 PF06191.7 EME76844.1 - 0.054 12.8 0.3 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF995) Laminin_G_3 PF13385.1 EME76844.1 - 0.14 12.4 5.8 5.7 7.1 0.1 3.4 2 1 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily Rad9 PF04139.8 EME76845.1 - 7.1e-53 179.3 0.6 3.8e-50 170.3 0.1 2.1 1 1 1 2 2 2 2 Rad9 ATP-grasp_4 PF13535.1 EME76845.1 - 0.062 13.0 0.9 0.087 12.5 0.1 1.6 2 0 0 2 2 2 0 ATP-grasp domain LRR_8 PF13855.1 EME76846.1 - 0.00084 19.0 11.9 6.6 6.5 0.0 6.7 7 1 1 8 8 8 3 Leucine rich repeat Phos_pyr_kin PF08543.7 EME76847.1 - 1.4e-79 266.7 4.8 2.1e-79 266.1 3.4 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EME76847.1 - 3.1e-51 174.0 1.4 4.9e-51 173.4 0.9 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EME76847.1 - 1.1e-07 31.2 0.9 2.2e-07 30.2 0.1 1.8 1 1 1 2 2 2 1 pfkB family carbohydrate kinase PcfK PF14058.1 EME76848.1 - 0.19 11.8 4.2 0.35 11.0 2.9 1.3 1 0 0 1 1 1 0 PcfK-like protein DUF1682 PF07946.9 EME76848.1 - 1.5 7.6 7.9 2 7.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Amidohydro_1 PF01979.15 EME76849.1 - 8.9e-42 143.9 0.0 1.2e-41 143.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EME76849.1 - 2.7e-09 36.7 0.2 3.4e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EME76849.1 - 2.4e-05 24.0 0.0 5.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EME76849.1 - 0.00013 22.0 0.0 0.079 12.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 EME76849.1 - 0.044 12.7 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Adenosine/AMP deaminase DCAF15_WD40 PF14939.1 EME76849.1 - 0.12 11.7 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat VPS9 PF02204.13 EME76852.1 - 1.4e-23 82.8 0.1 4.5e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 EME76853.1 - 2.6e-05 23.8 0.0 5.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EME76853.1 - 0.016 14.9 0.0 0.055 13.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EME76853.1 - 0.027 14.0 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein bZIP_2 PF07716.10 EME76857.1 - 0.0034 17.1 15.4 0.0085 15.8 10.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EME76857.1 - 0.012 15.5 11.7 0.029 14.3 8.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor TMEM247 PF15444.1 EME76857.1 - 0.069 12.9 0.6 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 DUF4355 PF14265.1 EME76857.1 - 0.58 10.1 7.9 1.4 8.9 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) bZIP_Maf PF03131.12 EME76857.1 - 3.1 8.1 13.9 0.23 11.7 5.6 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor RR_TM4-6 PF06459.7 EME76857.1 - 4.2 7.1 8.1 0.7 9.7 3.1 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Bac_rhamnosid PF05592.6 EME76858.1 - 1.8e-19 69.3 0.0 1.1e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EME76858.1 - 0.0011 17.7 0.1 0.0015 17.2 0.1 1.1 1 0 0 1 1 1 1 Trehalase DUF1737 PF08410.5 EME76858.1 - 0.027 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Ala_racemase_N PF01168.15 EME76859.1 - 3.2e-44 151.0 0.1 3.7e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain adh_short PF00106.20 EME76860.1 - 6.2e-30 104.3 0.1 7.9e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME76860.1 - 6e-22 78.5 0.1 7.5e-22 78.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME76860.1 - 7.3e-11 42.0 0.1 1e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME76860.1 - 1.6e-05 24.4 0.1 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME76860.1 - 0.011 15.5 0.3 0.028 14.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EME76860.1 - 0.013 14.4 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EME76860.1 - 0.014 15.4 0.5 0.033 14.1 0.1 1.7 2 1 0 2 2 2 0 NADH(P)-binding MFS_1 PF07690.11 EME76862.1 - 2.8e-44 151.2 40.9 2.8e-44 151.2 28.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME76862.1 - 2.4e-10 39.6 18.3 2.4e-10 39.6 12.7 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter ARPC4 PF05856.7 EME76863.1 - 0.042 13.2 0.0 0.068 12.5 0.0 1.3 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) hNIFK_binding PF12196.3 EME76863.1 - 0.28 10.5 1.9 1.3 8.4 0.0 2.4 2 1 0 2 2 2 0 FHA Ki67 binding domain of hNIFK UQ_con PF00179.21 EME76864.1 - 6.4e-25 87.2 0.0 9.5e-25 86.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF713 PF05218.9 EME76866.1 - 0.0054 16.4 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF713) PDH PF02153.12 EME76868.1 - 4.8e-15 55.1 0.1 7.2e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EME76868.1 - 4.9e-08 32.9 0.0 8.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME76868.1 - 1.2e-06 28.8 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EME76868.1 - 0.00012 21.8 0.1 0.00027 20.6 0.1 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EME76868.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EME76868.1 - 0.0023 17.3 0.0 0.005 16.2 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.4 EME76868.1 - 0.0071 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.7 EME76868.1 - 0.045 13.1 0.1 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Ribosomal_S11 PF00411.14 EME76869.1 - 5e-41 139.3 0.5 6.1e-41 139.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EME76869.1 - 0.047 12.5 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) ATP-grasp_4 PF13535.1 EME76870.1 - 1.7e-11 44.2 0.0 4.6e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME76870.1 - 2e-06 27.3 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EME76870.1 - 0.0044 15.8 0.0 0.063 12.0 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EME76870.1 - 0.0048 16.7 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 EME76870.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp UPF0370 PF13980.1 EME76871.1 - 0.088 12.6 0.4 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) FGGY_C PF02782.11 EME76872.1 - 8.7e-50 169.1 0.0 1.9e-49 168.0 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EME76872.1 - 2.7e-25 89.0 1.0 3.3e-22 78.9 0.0 3.1 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EME76872.1 - 0.00048 19.5 0.1 0.0017 17.7 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family adh_short PF00106.20 EME76873.1 - 7.6e-27 94.2 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME76873.1 - 3.2e-22 79.4 0.0 3.7e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME76873.1 - 2.5e-07 30.5 0.0 3.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME76873.1 - 4.1e-07 29.6 0.0 5.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EME76873.1 - 3.8e-05 22.9 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EME76873.1 - 0.0006 19.5 0.0 0.0061 16.2 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EME76873.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EME76873.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 EME76873.1 - 0.026 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EME76873.1 - 0.036 13.8 0.0 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EME76873.1 - 0.045 13.7 0.1 0.26 11.2 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding Profilin PF00235.14 EME76874.1 - 4.4e-43 146.2 0.4 4.9e-43 146.0 0.3 1.0 1 0 0 1 1 1 1 Profilin CHASE4 PF05228.8 EME76874.1 - 0.045 13.3 0.0 0.056 13.0 0.0 1.3 1 1 0 1 1 1 0 CHASE4 domain RRM_1 PF00076.17 EME76876.1 - 6e-13 48.2 0.0 6.5e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME76876.1 - 7.1e-12 45.1 0.0 8.2e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME76876.1 - 7.1e-08 32.1 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF328 PF03883.9 EME76876.1 - 0.036 13.3 0.1 0.036 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF328) AAA PF00004.24 EME76877.1 - 1.1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps36_ESCRT-II PF11605.3 EME76877.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF2296 PF10058.4 EME76881.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) TAF4 PF05236.9 EME76881.1 - 0.51 9.5 3.1 0.65 9.2 2.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BTB PF00651.26 EME76882.1 - 0.00048 20.0 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain FlaC_arch PF05377.6 EME76883.1 - 0.0025 17.6 10.5 1.2 9.1 0.0 5.6 5 1 0 5 5 5 2 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EME76883.1 - 0.014 15.2 7.4 0.014 15.2 5.1 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 EME76883.1 - 0.016 15.5 13.4 0.016 15.5 9.3 4.5 5 1 0 5 5 5 0 Snapin/Pallidin DUF2746 PF10874.3 EME76883.1 - 0.33 11.1 6.4 2.5 8.3 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) DASH_Dam1 PF08653.5 EME76883.1 - 0.43 10.3 4.0 7.2 6.4 0.1 4.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 Reo_sigmaC PF04582.7 EME76883.1 - 1.8 7.6 16.0 0.03 13.5 1.9 3.6 2 2 2 4 4 4 0 Reovirus sigma C capsid protein TNFR_c6 PF00020.13 EME76884.1 - 0.047 13.7 0.5 0.15 12.1 0.3 1.8 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region DUF2161 PF09929.4 EME76885.1 - 0.072 13.0 1.1 0.16 11.9 0.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) RRF_GI PF12614.3 EME76885.1 - 0.089 12.6 0.2 0.089 12.6 0.1 2.8 3 0 0 3 3 3 0 Ribosome recycling factor Reo_sigmaC PF04582.7 EME76885.1 - 0.16 11.0 5.1 0.3 10.2 2.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3166 PF11365.3 EME76885.1 - 0.29 11.6 6.9 0.46 10.9 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) WXG100 PF06013.7 EME76885.1 - 0.57 10.2 4.7 3 7.9 0.0 3.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 EME76885.1 - 0.76 9.6 31.6 0.29 10.9 5.9 3.5 3 2 0 3 3 2 0 Tropomyosin like V_ATPase_I PF01496.14 EME76885.1 - 1.1 6.9 16.1 2.3 5.9 9.3 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4570 PF15134.1 EME76885.1 - 1.3 8.8 11.5 0.12 12.2 2.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) ALMT PF11744.3 EME76885.1 - 1.9 7.0 7.2 2.9 6.4 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.11 EME76885.1 - 6.5 5.2 8.3 7.9 4.9 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.6 EME76885.1 - 7.1 6.6 15.6 11 5.9 2.1 4.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Matrilin_ccoil PF10393.4 EME76885.1 - 7.6 5.9 15.7 0.19 11.1 0.4 4.3 3 2 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin IBN_N PF03810.14 EME76886.1 - 1.1e-13 50.9 5.9 1.8e-11 43.7 0.0 5.1 6 0 0 6 6 6 1 Importin-beta N-terminal domain Cse1 PF08506.5 EME76886.1 - 7.6e-06 24.7 0.2 6e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.1 EME76886.1 - 3.8e-05 23.9 4.6 0.095 12.9 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Sigma70_ner PF04546.8 EME76886.1 - 0.0013 18.3 4.2 0.0033 17.0 2.9 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF2435 PF10363.4 EME76886.1 - 0.0015 18.3 0.4 0.0048 16.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 EME76886.1 - 0.0016 18.4 3.2 0.028 14.3 0.1 4.2 4 1 0 4 4 4 1 Exportin 1-like protein BUD22 PF09073.5 EME76886.1 - 0.14 11.2 7.8 0.23 10.5 5.4 1.3 1 0 0 1 1 1 0 BUD22 DSHCT PF08148.7 EME76887.1 - 2.4e-60 202.8 0.2 5e-60 201.8 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EME76887.1 - 2.3e-19 69.5 0.0 4.7e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME76887.1 - 2.7e-06 27.1 0.0 7.6e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EME76887.1 - 0.0016 17.6 0.1 0.0028 16.8 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 EME76887.1 - 0.016 15.0 0.0 0.36 10.6 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit GRP PF07172.6 EME76887.1 - 10 6.7 18.7 20 5.7 13.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family HMG_CoA_synt_C PF08540.5 EME76888.1 - 4.1e-104 348.0 1.8 5.2e-104 347.6 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EME76888.1 - 2.8e-96 320.0 0.1 4.5e-96 319.3 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Shisa PF13908.1 EME76889.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator dCMP_cyt_deam_1 PF00383.17 EME76890.1 - 1.4e-25 88.9 0.3 1.7e-25 88.5 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EME76890.1 - 0.0012 18.7 1.1 0.026 14.3 0.1 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 EME76890.1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase DUF1765 PF08578.5 EME76891.1 - 2.1e-39 134.4 1.4 4.7e-39 133.3 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Adaptin_N PF01602.15 EME76894.1 - 6.6e-125 417.4 6.0 8.1e-125 417.1 4.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EME76894.1 - 4.8e-42 142.4 0.0 1.5e-41 140.8 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EME76894.1 - 1.3e-20 73.8 0.0 2.4e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain FAD_binding_3 PF01494.14 EME76895.1 - 1.8e-05 24.0 0.0 3.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EME76895.1 - 0.005 15.6 0.0 0.0076 15.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EME76895.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase BetR PF08667.5 EME76897.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 BetR domain GFO_IDH_MocA PF01408.17 EME76900.1 - 1.4e-18 67.5 0.0 2.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME76900.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EME76900.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polyketide_cyc2 PF10604.4 EME76901.1 - 6.5e-11 42.5 0.0 7.2e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CFEM PF05730.6 EME76902.1 - 5e-08 32.6 16.0 9.6e-08 31.7 11.1 1.5 1 0 0 1 1 1 1 CFEM domain DUF4126 PF13548.1 EME76902.1 - 0.19 11.1 5.4 0.062 12.7 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4126) MAP65_ASE1 PF03999.7 EME76902.1 - 3.2 6.2 4.7 3.7 6.0 3.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GCIP PF13324.1 EME76903.1 - 4.7e-09 35.8 0.3 7.4e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Rxt3 PF08642.5 EME76903.1 - 0.11 12.7 0.1 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 HeLo PF14479.1 EME76903.1 - 0.21 11.3 3.1 16 5.1 0.1 3.1 2 1 0 3 3 3 0 Prion-inhibition and propagation MscS_porin PF12795.2 EME76903.1 - 0.55 9.5 3.1 3.1 7.0 0.1 2.4 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain TT_ORF2 PF02957.10 EME76903.1 - 0.6 10.8 3.3 1.2 9.8 2.3 1.4 1 0 0 1 1 1 0 TT viral ORF2 DUF1096 PF06493.6 EME76904.1 - 2.8 7.9 41.1 0.65 9.9 16.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Cupin_2 PF07883.6 EME76905.1 - 1e-08 34.5 0.1 0.0056 16.1 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 EME76905.1 - 0.001 18.7 0.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 EME76905.1 - 0.0036 16.9 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain EutQ PF06249.7 EME76905.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Pam16 PF03656.8 EME76906.1 - 1.3e-34 118.7 0.3 1.6e-34 118.4 0.2 1.1 1 0 0 1 1 1 1 Pam16 AKAP2_C PF15304.1 EME76906.1 - 0.015 14.9 0.2 0.019 14.6 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus UTP15_C PF09384.5 EME76906.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UTP15 C terminal Pkinase PF00069.20 EME76907.1 - 2.7e-05 23.4 0.0 0.00017 20.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME76907.1 - 0.15 11.1 0.0 9.5 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase PFK PF00365.15 EME76908.1 - 4.2e-165 547.6 0.3 5.6e-121 402.8 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF1136 PF06582.7 EME76908.1 - 0.17 11.6 0.4 0.49 10.1 0.2 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) HTH_38 PF13936.1 EME76909.1 - 1.2e-12 47.1 5.4 0.0054 16.2 0.1 6.2 6 0 0 6 6 6 4 Helix-turn-helix domain HTH_7 PF02796.10 EME76909.1 - 5.2e-08 32.6 0.1 0.11 12.4 0.0 5.1 5 1 0 5 5 5 2 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EME76909.1 - 2.2e-07 30.2 2.1 0.9 9.0 0.0 5.7 6 0 0 6 6 6 3 Sigma-70, region 4 HTH_23 PF13384.1 EME76909.1 - 1.8e-06 27.4 5.1 0.45 10.2 0.0 5.9 6 0 0 6 6 6 2 Homeodomain-like domain GerE PF00196.14 EME76909.1 - 5.5e-05 22.3 0.0 6.5 6.1 0.0 4.8 5 0 0 5 5 5 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.11 EME76909.1 - 0.00094 18.4 2.5 11 5.3 0.0 5.0 5 0 0 5 5 5 2 Sigma-70, region 4 HTH_28 PF13518.1 EME76909.1 - 0.014 15.4 3.1 29 4.7 0.0 5.2 5 0 0 5 5 5 0 Helix-turn-helix domain DUF2481 PF10654.4 EME76909.1 - 0.074 12.7 0.0 38 3.9 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2481) Myb_DNA-bind_3 PF12776.2 EME76910.1 - 0.014 16.0 0.1 0.024 15.2 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain AAA PF00004.24 EME76911.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME76911.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME76911.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EME76911.1 - 1.4e-06 28.3 0.1 3.4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME76911.1 - 4e-06 26.9 0.1 0.00025 21.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME76911.1 - 6.9e-05 23.6 0.0 0.00015 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME76911.1 - 7.5e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME76911.1 - 0.00013 21.6 0.1 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EME76911.1 - 0.0004 19.8 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EME76911.1 - 0.00098 17.9 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EME76911.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME76911.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME76911.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EME76911.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EME76911.1 - 0.0038 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EME76911.1 - 0.0043 16.1 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EME76911.1 - 0.0063 16.8 0.0 0.029 14.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EME76911.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EME76911.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EME76911.1 - 0.017 14.5 0.0 0.084 12.3 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EME76911.1 - 0.018 14.4 0.1 0.09 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EME76911.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EME76911.1 - 0.021 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EME76911.1 - 0.03 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EME76911.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EME76911.1 - 0.052 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.4 EME76911.1 - 0.077 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NB-ARC PF00931.17 EME76911.1 - 0.08 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EME76911.1 - 0.084 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EME76911.1 - 0.095 12.3 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF3176 PF11374.3 EME76912.1 - 3.2e-36 123.5 0.9 4.2e-36 123.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF2254 PF10011.4 EME76912.1 - 0.18 10.2 2.0 0.27 9.6 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) MARVEL PF01284.18 EME76912.1 - 0.32 10.7 4.1 1.3 8.7 2.8 1.8 1 1 0 1 1 1 0 Membrane-associating domain ATG11 PF10377.4 EME76914.1 - 2.9e-32 111.2 0.0 2.9e-32 111.2 0.0 3.5 3 1 0 3 3 3 1 Autophagy-related protein 11 IncA PF04156.9 EME76914.1 - 0.0061 16.1 22.7 0.0061 16.1 15.7 5.9 3 2 2 5 5 5 2 IncA protein CorA PF01544.13 EME76916.1 - 5.2e-07 28.9 0.2 7.6e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cyt_c_ox_IV PF12270.3 EME76916.1 - 0.089 12.5 1.2 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Methyltransf_31 PF13847.1 EME76917.1 - 1.6e-13 50.4 0.0 3.3e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME76917.1 - 1.9e-13 50.9 0.0 2.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME76917.1 - 3.2e-11 43.5 0.0 1.5e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME76917.1 - 4.4e-11 42.7 0.0 5.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME76917.1 - 1.4e-10 41.4 0.0 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME76917.1 - 1e-07 32.2 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME76917.1 - 0.00012 21.3 0.0 0.00043 19.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME76917.1 - 0.00014 21.9 0.0 0.00035 20.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME76917.1 - 0.00085 18.4 0.1 0.83 8.6 0.0 2.1 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Rsm22 PF09243.5 EME76917.1 - 0.0025 16.9 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.9 EME76917.1 - 0.0099 15.2 0.0 0.027 13.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain DUF460 PF04312.8 EME76917.1 - 0.049 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Mannitol_dh PF01232.18 EME76917.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain CorA PF01544.13 EME76919.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4079 PF13301.1 EME76919.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) GST_N_3 PF13417.1 EME76920.1 - 1.7e-10 40.9 0.0 2.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME76920.1 - 1.4e-09 37.9 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME76920.1 - 7.9e-06 25.7 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 EME76921.1 - 6.9e-87 291.8 23.5 8.7e-87 291.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME76921.1 - 3.5e-17 62.1 36.2 3e-16 59.1 17.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EME76921.1 - 2.6e-06 26.2 2.5 4.8e-06 25.3 1.8 1.4 1 0 0 1 1 1 1 Reduced folate carrier MFS_2 PF13347.1 EME76921.1 - 0.00022 19.7 6.0 0.00022 19.7 4.2 3.4 2 2 2 4 4 4 2 MFS/sugar transport protein Alpha-amylase PF00128.19 EME76922.1 - 1.6e-93 313.6 0.0 2.3e-93 313.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 EME76922.1 - 0.0029 17.7 0.0 0.008 16.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.13 EME76922.1 - 0.016 15.3 0.0 0.091 12.9 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 EME76922.1 - 0.027 13.4 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_1 PF00232.13 EME76923.1 - 7.4e-115 383.7 2.5 1e-114 383.2 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AMP-binding PF00501.23 EME76924.1 - 5.6e-72 242.4 0.0 7.9e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EME76924.1 - 2e-60 203.7 0.0 3.1e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EME76924.1 - 5.1e-10 39.4 0.0 9.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EME76924.1 - 3.5e-09 36.4 0.0 2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EME76924.1 - 8e-07 29.9 0.0 3.6e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EME76924.1 - 3e-05 22.8 0.0 8.4e-05 21.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family IBR PF01485.16 EME76925.1 - 2.6e-14 52.8 42.7 8.6e-08 31.9 8.0 3.4 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EME76925.1 - 0.0091 16.0 4.8 0.0091 16.0 3.3 4.7 3 3 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.18 EME76925.1 - 0.022 14.6 1.6 0.022 14.6 1.1 5.0 5 0 0 5 5 5 0 Zinc knuckle zf-C3HC4 PF00097.20 EME76925.1 - 0.029 14.0 5.9 0.029 14.0 4.1 5.1 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) dCMP_cyt_deam_1 PF00383.17 EME76928.1 - 2.5e-07 30.2 1.3 0.0011 18.5 0.0 3.6 4 0 0 4 4 4 2 Cytidine and deoxycytidylate deaminase zinc-binding region DUF3721 PF12518.3 EME76932.1 - 0.038 13.5 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function NUDIX PF00293.23 EME76934.1 - 1.6e-12 47.2 0.2 3.1e-12 46.2 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain Bud13 PF09736.4 EME76935.1 - 1.7e-44 151.5 17.8 1.7e-44 151.5 12.4 2.9 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex AAA_11 PF13086.1 EME76935.1 - 0.043 13.3 3.1 0.069 12.7 2.1 1.4 1 0 0 1 1 1 0 AAA domain DNA_binding_1 PF01035.15 EME76936.1 - 2.3e-20 72.1 0.4 4e-20 71.3 0.3 1.4 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CoA_transf_3 PF02515.12 EME76939.1 - 2.6e-58 196.3 0.2 5e-58 195.5 0.0 1.5 2 0 0 2 2 2 1 CoA-transferase family III Lum_binding PF00677.12 EME76940.1 - 3.7e-39 132.5 1.3 9.3e-21 73.5 0.1 2.2 2 0 0 2 2 2 2 Lumazine binding domain Gifsy-2 PF13856.1 EME76940.1 - 0.054 13.6 0.0 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage Ribosomal_L30_N PF08079.7 EME76941.1 - 3.4e-25 87.8 22.4 7.9e-25 86.6 15.5 1.7 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EME76941.1 - 7.2e-20 70.3 3.4 1e-19 69.8 1.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EAP30 PF04157.11 EME76942.1 - 1.5e-54 184.5 0.0 1.7e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family SUFU PF05076.8 EME76943.1 - 0.0034 16.9 0.0 0.008 15.7 0.0 1.6 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) UFD1 PF03152.9 EME76944.1 - 4.9e-26 90.9 0.0 1.8e-21 76.0 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zinc_ribbon_5 PF13719.1 EME76944.1 - 0.041 13.4 2.9 0.3 10.7 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EME76944.1 - 0.042 13.5 2.4 0.48 10.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain HTH_38 PF13936.1 EME76944.1 - 0.073 12.6 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF383 PF04063.9 EME76945.1 - 7.6e-69 231.1 0.0 3.6e-68 228.8 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EME76945.1 - 6.5e-21 73.6 0.4 1.8e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) TMF_DNA_bd PF12329.3 EME76946.1 - 0.0015 18.2 16.0 0.0015 18.2 11.1 18.5 12 6 8 20 20 20 6 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EME76946.1 - 0.0026 17.5 21.6 0.0026 17.5 15.0 10.6 5 2 6 11 11 11 5 Autophagy protein 16 (ATG16) WD40_alt PF14077.1 EME76946.1 - 0.43 10.2 12.7 0.38 10.4 0.1 5.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif Ank_2 PF12796.2 EME76949.1 - 8.2e-27 93.3 4.3 5.8e-09 36.1 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EME76949.1 - 6.8e-23 80.1 2.4 0.00045 20.3 0.0 6.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME76949.1 - 3.3e-21 73.2 0.0 0.0014 18.6 0.0 6.9 7 0 0 7 7 5 4 Ankyrin repeat Ank PF00023.25 EME76949.1 - 5.5e-21 73.2 1.5 4.3e-05 23.1 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EME76949.1 - 2.5e-18 66.0 0.8 1.2e-07 32.0 0.0 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.7 EME76949.1 - 1.2e-09 38.0 0.2 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME76949.1 - 3.9e-06 26.9 0.2 1.6e-05 24.9 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME76949.1 - 0.00018 21.6 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME76949.1 - 0.00039 19.5 0.0 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 EME76949.1 - 0.065 13.1 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EME76949.1 - 0.073 13.8 0.0 0.94 10.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EME76949.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EME76949.1 - 0.26 11.4 0.0 0.58 10.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1338 PF07063.8 EME76950.1 - 5.2e-78 262.1 0.0 6.4e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) PIG-Y PF15159.1 EME76951.1 - 0.6 10.3 4.5 1.4 9.1 3.1 1.7 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Cation_efflux PF01545.16 EME76952.1 - 2.5e-28 98.9 6.3 3.1e-28 98.6 4.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1290 PF06947.7 EME76952.1 - 0.017 15.0 0.3 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) DUF2104 PF09877.4 EME76952.1 - 0.067 13.1 0.3 0.26 11.2 0.2 2.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) Aa_trans PF01490.13 EME76953.1 - 2.2e-32 112.0 40.0 2.5e-32 111.8 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNase_H PF00075.19 EME76954.1 - 3.6e-17 62.9 0.0 5.4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EME76954.1 - 0.00014 21.5 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like PRKCSH-like PF12999.2 EME76956.1 - 3e-42 144.1 9.6 5e-42 143.4 3.3 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EME76956.1 - 3.7e-32 110.9 1.9 2.2e-31 108.3 0.5 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EME76956.1 - 9.6e-11 42.3 1.4 2.6e-10 40.9 1.0 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG16 PF08614.6 EME76956.1 - 0.0099 15.7 8.1 1.7 8.4 1.2 3.1 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) DUF745 PF05335.8 EME76956.1 - 0.017 14.6 8.6 0.11 11.9 3.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Sec2p PF06428.6 EME76956.1 - 0.021 14.6 10.5 1.9 8.3 0.3 3.4 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Sec8_exocyst PF04048.9 EME76956.1 - 0.052 13.1 8.2 0.73 9.4 0.6 2.7 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain MscS_porin PF12795.2 EME76956.1 - 0.069 12.4 13.2 2.8 7.2 6.8 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Prominin PF05478.6 EME76956.1 - 0.089 10.3 4.3 0.2 9.1 0.8 2.1 1 1 1 2 2 2 0 Prominin Atg14 PF10186.4 EME76956.1 - 0.11 11.4 11.1 0.076 11.9 5.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 KxDL PF10241.4 EME76956.1 - 0.7 9.8 7.1 16 5.5 0.0 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein CENP-F_leu_zip PF10473.4 EME76956.1 - 0.87 9.4 14.6 0.7 9.7 7.1 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0449 PF15136.1 EME76956.1 - 1.5 9.0 5.6 1.6 9.0 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised protein family UPF0449 Gal4_dimer PF03902.8 EME76956.1 - 2.2 8.2 10.9 0.076 12.9 1.1 2.8 4 0 0 4 4 3 0 Gal4-like dimerisation domain IncA PF04156.9 EME76956.1 - 2.5 7.6 13.6 6.3 6.3 6.7 2.4 2 1 0 2 2 2 0 IncA protein TBPIP PF07106.8 EME76956.1 - 2.7 7.5 10.5 4.9 6.6 0.8 3.0 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FTA4 PF13093.1 EME76956.1 - 2.9 7.2 7.5 1.7 8.0 3.5 1.8 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin_2 PF01920.15 EME76956.1 - 4 7.2 14.3 18 5.1 0.3 3.5 3 0 0 3 3 3 0 Prefoldin subunit CDC45 PF02724.9 EME76957.1 - 2.8 5.8 10.2 3.2 5.6 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TIMELESS_C PF05029.8 EME76957.1 - 9.6 5.0 15.5 13 4.5 10.8 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region DPM3 PF08285.6 EME76958.1 - 1e-32 111.8 0.0 1.1e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RNA_pol_N PF01194.12 EME76959.1 - 3.7e-28 97.3 0.7 4.5e-28 97.0 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 EME76960.1 - 4.5e-10 39.0 2.6 0.0025 17.6 0.0 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat PV-1 PF06637.6 EME76961.1 - 3.6 6.0 4.2 5.6 5.4 2.9 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Abhydrolase_3 PF07859.8 EME76962.1 - 4.4e-40 137.5 0.1 6e-31 107.6 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EME76962.1 - 1.8e-14 53.1 0.0 3.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EME76962.1 - 0.00016 20.5 0.0 0.16 10.6 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.2 EME76962.1 - 0.00047 20.1 0.3 0.0011 18.9 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME76962.1 - 0.0027 17.4 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME76962.1 - 0.073 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family WGG PF10273.4 EME76963.1 - 2.4e-24 85.1 0.1 2.4e-24 85.1 0.1 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 DUF3752 PF12572.3 EME76963.1 - 0.082 13.0 1.9 0.12 12.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Recombinase PF07508.8 EME76963.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Recombinase FMN_dh PF01070.13 EME76964.1 - 1.4e-119 399.0 0.1 1.8e-119 398.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EME76964.1 - 2.1e-21 75.4 0.0 4.5e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EME76964.1 - 2.8e-07 29.7 0.0 5.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EME76964.1 - 0.0029 16.5 1.4 0.0062 15.4 0.1 2.2 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EME76964.1 - 0.0085 15.3 0.1 0.84 8.8 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EME76964.1 - 0.017 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DMA PF03474.9 EME76964.1 - 0.029 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif ThiG PF05690.9 EME76964.1 - 0.092 11.8 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LON PF02190.11 EME76965.1 - 1.4e-25 90.2 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 EME76965.1 - 1e-05 25.2 7.1 2e-05 24.3 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME76965.1 - 2e-05 24.1 4.6 3.5e-05 23.3 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME76965.1 - 2.9e-05 23.7 4.3 4.9e-05 22.9 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME76965.1 - 7.1e-05 22.7 4.7 0.00012 22.0 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME76965.1 - 0.00029 20.3 2.4 0.00066 19.2 1.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 EME76965.1 - 0.00045 19.8 4.8 0.00071 19.1 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME76965.1 - 0.0005 19.8 3.6 0.00094 19.0 2.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME76965.1 - 0.0048 16.5 2.3 0.0048 16.5 1.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-P11 PF03854.9 EME76965.1 - 0.019 14.4 3.5 0.034 13.6 2.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-rbx1 PF12678.2 EME76965.1 - 0.12 12.4 3.7 0.23 11.5 2.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_1 PF00515.23 EME76966.1 - 1.4e-16 59.2 7.0 1e-06 28.1 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME76966.1 - 1.3e-15 55.9 4.7 2.7e-05 23.7 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EME76966.1 - 2e-14 52.9 2.7 1.3e-09 37.5 0.1 3.6 1 1 2 3 3 3 3 TPR repeat PB1 PF00564.19 EME76966.1 - 3.7e-14 52.1 0.2 6.5e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.1 EME76966.1 - 2.1e-11 42.7 2.0 0.002 17.7 0.0 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME76966.1 - 2.7e-08 33.6 1.7 0.00013 21.8 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME76966.1 - 4.9e-08 32.1 3.4 7.5e-05 22.2 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME76966.1 - 8.3e-08 32.1 0.2 6.8 7.3 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME76966.1 - 3.1e-05 24.5 9.6 0.012 16.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME76966.1 - 0.00047 20.5 4.0 0.68 10.7 0.0 4.6 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME76966.1 - 0.00058 19.8 0.2 0.071 13.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME76966.1 - 0.0016 18.2 0.6 0.86 9.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EME76966.1 - 0.012 15.6 4.1 0.015 15.4 0.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Na_Ca_ex PF01699.19 EME76968.1 - 3.3e-31 107.7 27.4 1.6e-18 66.6 8.8 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EME76968.1 - 1e-11 45.0 10.1 1e-11 45.0 7.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Pkinase PF00069.20 EME76969.1 - 8.4e-54 182.4 0.0 1.8e-53 181.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME76969.1 - 7.5e-24 84.1 0.0 1.6e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME76969.1 - 0.0035 17.1 0.1 0.0035 17.1 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME76969.1 - 0.0072 15.6 0.2 0.039 13.2 0.1 2.1 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EME76969.1 - 0.029 14.4 0.1 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) A1_Propeptide PF07966.7 EME76971.1 - 0.83 9.5 6.5 6.8 6.6 0.1 2.9 3 0 0 3 3 3 0 A1 Propeptide F-112 PF09645.5 EME76976.1 - 0.26 11.1 3.6 0.63 9.9 2.5 1.6 1 0 0 1 1 1 0 F-112 protein Adeno_E4_ORF3 PF06931.6 EME76981.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein DUF3093 PF11292.3 EME76985.1 - 0.082 12.7 0.5 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) MAP2_projctn PF08377.5 EME76986.1 - 0.41 8.1 0.0 0.62 7.5 0.0 1.1 1 0 0 1 1 1 0 MAP2/Tau projection domain DUF4487 PF14868.1 EME76990.1 - 0.015 14.0 0.2 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) zf-LSD1 PF06943.7 EME76993.1 - 0.63 9.7 3.4 1.4 8.5 0.3 2.6 2 0 0 2 2 2 0 LSD1 zinc finger DUF2063 PF09836.4 EME76995.1 - 0.066 13.2 0.2 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) Ectatomin PF06457.6 EME76999.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ectatomin ubiquitin PF00240.18 EME77004.1 - 8.4e-09 34.7 0.6 8e-08 31.5 0.2 2.2 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EME77004.1 - 0.00078 19.0 0.2 0.0023 17.5 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME77004.1 - 0.89 9.7 3.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF2201_N PF13203.1 EME77004.1 - 3.5 6.7 13.9 7.5 5.6 9.6 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EME77004.1 - 5.2 4.9 20.8 7.8 4.3 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EME77011.1 - 0.00028 19.7 36.0 0.00034 19.4 25.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop53 PF07767.6 EME77011.1 - 0.0035 16.4 5.7 0.0041 16.1 3.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 EME77011.1 - 0.18 9.8 14.4 0.21 9.5 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EME77011.1 - 0.22 9.3 24.0 0.27 9.1 16.6 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EME77011.1 - 0.35 10.0 13.3 0.44 9.7 9.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T IFT57 PF10498.4 EME77011.1 - 1.8 7.2 9.7 2.3 6.8 6.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Utp14 PF04615.8 EME77011.1 - 2.9 5.9 15.7 3.3 5.7 10.9 1.0 1 0 0 1 1 1 0 Utp14 protein SGT1 PF07093.6 EME77011.1 - 3 6.1 17.6 4.7 5.4 12.2 1.3 1 0 0 1 1 1 0 SGT1 protein GCIP PF13324.1 EME77011.1 - 4.5 6.3 8.6 5.3 6.1 5.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Trypan_PARP PF05887.6 EME77011.1 - 4.7 7.0 6.8 5.8 6.7 4.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 EME77011.1 - 9.6 5.3 23.8 14 4.7 16.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pheromone PF08015.6 EME77013.1 - 1.6 9.5 4.7 1.5 9.7 1.1 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone DEAD PF00270.24 EME77021.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3340 PF11818.3 EME77027.1 - 0.25 11.3 4.9 0.37 10.7 3.4 1.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) CDC45 PF02724.9 EME77027.1 - 1.3 6.9 7.9 1.9 6.4 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3123 PF11321.3 EME77027.1 - 1.5 9.1 5.6 3.6 7.9 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Borrelia_P83 PF05262.6 EME77029.1 - 0.68 8.1 12.1 1.2 7.3 8.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Pox_Ag35 PF03286.9 EME77029.1 - 0.7 9.3 17.5 0.26 10.7 8.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNA_polI_A34 PF08208.6 EME77029.1 - 1.1 8.8 32.6 0.013 15.1 15.6 2.5 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 MIP-T3 PF10243.4 EME77029.1 - 1.3 7.4 32.1 0.0052 15.3 15.3 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EME77029.1 - 3.1 7.6 17.2 0.19 11.6 8.1 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ADH_N PF08240.7 EME77033.1 - 0.02 14.6 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain CASP_C PF08172.7 EME77036.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 CASP C terminal DUF605 PF04652.11 EME77036.1 - 1.2 8.4 23.6 2.7 7.3 16.3 1.6 1 0 0 1 1 1 0 Vta1 like GDC-P PF02347.11 EME77039.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein MCE PF02470.15 EME77042.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 mce related protein Peptidase_C48 PF02902.14 EME77045.1 - 1.4e-06 28.0 0.1 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Retro_M PF02813.9 EME77047.1 - 0.073 13.2 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Retroviral M domain DUF3291 PF11695.3 EME77052.1 - 0.031 13.6 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3291) Serglycin PF04360.7 EME77054.1 - 0.043 13.5 0.2 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 Serglycin GAS PF13851.1 EME77055.1 - 0.0024 17.0 58.8 0.0056 15.8 11.0 3.4 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EME77055.1 - 0.036 13.8 26.5 0.051 13.3 2.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EME77055.1 - 0.067 13.0 60.1 0.022 14.5 5.3 5.5 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EME77055.1 - 0.24 11.2 66.4 0.73 9.7 6.5 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 EME77055.1 - 0.38 10.2 52.3 0.05 13.1 5.2 4.1 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EME77055.1 - 1.2 8.7 69.2 0.74 9.3 16.4 3.6 1 1 2 3 3 3 0 IncA protein Filament PF00038.16 EME77055.1 - 1.6 8.1 58.3 1.4 8.2 30.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 EME77055.1 - 1.7 8.4 59.1 0.64 9.8 3.0 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med15 PF09606.5 EME77055.1 - 5.2 5.1 31.5 6.5 4.8 21.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tropomyosin_1 PF12718.2 EME77055.1 - 5.2 6.9 63.7 0.04 13.7 12.9 3.2 1 1 0 2 2 1 0 Tropomyosin like V_ATPase_I PF01496.14 EME77055.1 - 5.4 4.7 43.2 1.8 6.3 7.9 2.5 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EME77055.1 - 6.1 5.9 14.5 3.6 6.6 3.5 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EME77055.1 - 6.8 6.4 58.4 17 5.1 19.5 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMEM154 PF15102.1 EME77056.1 - 4.1e-06 26.5 2.4 9.4e-06 25.3 1.7 1.6 1 0 0 1 1 1 1 TMEM154 protein family Rifin_STEVOR PF02009.11 EME77056.1 - 1.6e-05 24.7 2.6 1.6e-05 24.7 1.8 1.4 2 0 0 2 2 1 1 Rifin/stevor family DUF912 PF06024.7 EME77056.1 - 0.0001 22.3 1.4 0.00015 21.7 0.1 1.9 2 0 0 2 2 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Endomucin PF07010.7 EME77056.1 - 0.0002 20.7 1.4 0.00026 20.4 1.0 1.2 1 0 0 1 1 1 1 Endomucin Synaptobrevin PF00957.16 EME77056.1 - 0.002 17.6 4.2 0.002 17.6 2.9 1.6 2 0 0 2 2 1 1 Synaptobrevin DUF4400 PF14348.1 EME77056.1 - 0.0069 15.7 0.2 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) Pex24p PF06398.6 EME77056.1 - 0.0074 15.1 0.1 0.011 14.5 0.1 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin OPT PF03169.10 EME77056.1 - 0.0075 14.7 0.1 0.01 14.3 0.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M56 PF05569.6 EME77056.1 - 0.015 14.3 1.3 0.022 13.7 0.9 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Baculo_11_kDa PF06143.6 EME77056.1 - 0.015 14.6 0.1 0.057 12.7 0.1 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family E1-E2_ATPase PF00122.15 EME77056.1 - 0.039 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Tetraspannin PF00335.15 EME77056.1 - 0.058 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family ODV-E18 PF10717.4 EME77056.1 - 0.058 12.8 1.9 0.16 11.4 1.3 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 LRR19-TM PF15176.1 EME77056.1 - 0.067 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF1510 PF07423.6 EME77056.1 - 0.07 12.4 0.1 0.07 12.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) DUF2207 PF09972.4 EME77056.1 - 0.12 10.9 0.1 0.16 10.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3619 PF12279.3 EME77056.1 - 0.16 12.0 0.2 0.45 10.6 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3619) Baculo_E56 PF04639.7 EME77056.1 - 0.35 9.4 3.2 0.77 8.3 2.2 1.5 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Glycophorin_A PF01102.13 EME77056.1 - 0.36 10.5 5.2 0.59 9.9 3.0 1.7 1 1 0 1 1 1 0 Glycophorin A Fusion_gly PF00523.13 EME77056.1 - 0.54 8.2 5.5 0.79 7.7 3.8 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 GP41 PF00517.12 EME77056.1 - 0.72 9.3 4.1 1.2 8.6 2.9 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF3753 PF12575.3 EME77056.1 - 1.1 9.0 8.4 3.2 7.6 5.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF818 PF05677.7 EME77056.1 - 1.5 7.4 6.6 2.2 6.9 4.5 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Tenui_PVC2 PF06656.6 EME77056.1 - 4.9 4.8 9.0 7.4 4.2 6.3 1.2 1 0 0 1 1 1 0 Tenuivirus PVC2 protein DUF3139 PF11337.3 EME77056.1 - 6 7.2 7.2 14 6.0 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SHP PF03579.8 EME77056.1 - 8.1 5.8 12.0 16 4.9 8.3 1.4 1 0 0 1 1 1 0 Small hydrophobic protein Mononeg_RNA_pol PF00946.14 EME77063.1 - 1.3e-82 277.7 0.0 1.6e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Mononegavirales RNA dependent RNA polymerase CATSPERB PF15149.1 EME77066.1 - 0.14 10.2 0.5 0.16 10.1 0.3 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family TFIIA PF03153.8 EME77066.1 - 0.21 11.4 2.7 0.24 11.2 1.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DCR PF14047.1 EME77066.1 - 0.71 10.2 5.2 4.3 7.6 0.2 2.4 2 1 0 2 2 2 0 Dppa2/4 conserved region PLRV_ORF5 PF01690.12 EME77069.1 - 1.1 8.3 17.4 1.4 7.9 12.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein YqzE PF14038.1 EME77078.1 - 0.082 12.6 4.7 0.18 11.5 3.2 1.5 1 0 0 1 1 1 0 YqzE-like protein zf-Paramyx-P PF13008.2 EME77080.1 - 0.068 12.3 0.7 2.5 7.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-binding domain of Paramyxoviridae V protein HCV_NS4a PF01006.15 EME77081.1 - 0.059 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Zn_clus PF00172.13 EME77086.1 - 4.9e-08 32.7 9.5 7.8e-08 32.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRO1 PF03097.13 EME77086.1 - 0.048 12.4 1.7 0.059 12.1 1.2 1.0 1 0 0 1 1 1 0 BRO1-like domain PIH1 PF08190.7 EME77086.1 - 0.095 12.1 0.8 0.11 11.9 0.6 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4414 PF14377.1 EME77089.1 - 0.012 15.4 1.5 0.019 14.8 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Peptidase_C9 PF01707.11 EME77089.1 - 0.083 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C9 DUF983 PF06170.7 EME77094.1 - 0.033 14.3 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Tmemb_55A PF09788.4 EME77094.1 - 0.057 12.5 0.1 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A DUF2116 PF09889.4 EME77094.1 - 0.13 12.0 0.8 0.31 10.8 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4044 PF13253.1 EME77094.1 - 0.57 9.3 6.5 1.1 8.5 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) IncA PF04156.9 EME77095.1 - 0.0023 17.5 7.3 0.18 11.3 2.2 2.7 1 1 1 2 2 2 2 IncA protein Spc7 PF08317.6 EME77095.1 - 0.0036 16.0 14.5 0.008 14.8 0.9 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein FliJ PF02050.11 EME77095.1 - 0.0044 17.0 8.5 0.024 14.6 0.1 3.4 3 1 1 4 4 3 1 Flagellar FliJ protein Flagellin_C PF00700.16 EME77095.1 - 0.0056 16.8 22.1 0.26 11.4 0.1 4.3 2 2 1 3 3 3 2 Bacterial flagellin C-terminal helical region AAA_13 PF13166.1 EME77095.1 - 0.0072 14.8 12.1 0.008 14.6 7.8 1.4 1 1 0 1 1 1 1 AAA domain Tropomyosin PF00261.15 EME77095.1 - 0.019 14.0 10.3 0.034 13.2 3.3 2.7 1 1 1 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.2 EME77095.1 - 0.021 14.6 10.5 0.19 11.5 0.8 3.1 1 1 2 3 3 3 0 Tropomyosin like RRF PF01765.14 EME77095.1 - 0.046 13.1 4.9 0.45 9.9 0.4 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF948 PF06103.6 EME77095.1 - 0.33 10.8 18.0 0.52 10.1 4.5 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2130 PF09903.4 EME77095.1 - 0.74 8.5 6.1 0.28 9.8 1.7 2.1 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF3552 PF12072.3 EME77095.1 - 0.85 8.7 9.0 0.2 10.8 1.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.3 EME77095.1 - 0.9 9.3 13.4 7 6.5 0.7 4.5 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 EME77095.1 - 2 8.2 14.5 1.7 8.4 0.7 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3708 PF12501.3 EME77095.1 - 2.6 7.8 9.9 0.45 10.3 3.1 2.2 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter XhlA PF10779.4 EME77095.1 - 2.7 7.9 14.2 4.5 7.2 1.6 4.1 2 2 3 5 5 5 0 Haemolysin XhlA Reo_sigmaC PF04582.7 EME77095.1 - 3.2 6.8 26.1 0.44 9.6 5.3 2.6 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 EME77095.1 - 4.1 6.7 12.8 1.8e+02 1.3 8.9 2.6 1 1 0 1 1 1 0 Intermediate filament protein DUF4200 PF13863.1 EME77095.1 - 4.1 7.3 6.0 27 4.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cytochrom_B562 PF07361.6 EME77095.1 - 4.8 7.6 8.5 5.8 7.3 0.5 3.3 1 1 1 2 2 2 0 Cytochrome b562 Bacillus_HBL PF05791.6 EME77095.1 - 6.7 6.0 12.9 20 4.4 4.5 3.1 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_TATA_bd PF12325.3 EME77096.1 - 0.016 14.9 1.2 0.016 14.9 0.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Caps_synth_GfcC PF06251.6 EME77096.1 - 0.12 11.5 2.1 0.21 10.7 1.4 1.3 1 0 0 1 1 1 0 Capsule biosynthesis GfcC IncA PF04156.9 EME77096.1 - 5.6 6.5 7.8 14 5.2 5.5 1.5 1 1 0 1 1 1 0 IncA protein DUF155 PF02582.9 EME77100.1 - 0.26 11.1 2.9 0.34 10.8 0.7 2.1 2 1 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Fib_alpha PF08702.5 EME77100.1 - 0.83 9.7 6.0 1.6 8.8 4.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NADH_B2 PF14813.1 EME77103.1 - 0.044 13.4 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Nop14 PF04147.7 EME77119.1 - 0.01 13.8 26.6 0.015 13.2 18.5 1.2 1 0 0 1 1 1 1 Nop14-like family Tom37_C PF11801.3 EME77119.1 - 1 9.1 3.9 2.5 7.9 2.7 1.7 1 0 0 1 1 1 0 Tom37 C-terminal domain RRN3 PF05327.6 EME77119.1 - 3 5.8 14.3 4.4 5.2 9.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.5 EME77122.1 - 0.18 10.8 19.3 0.46 9.5 13.4 1.6 1 0 0 1 1 1 0 BUD22 Pheromone PF08015.6 EME77127.1 - 0.55 11.0 5.1 3 8.7 0.6 2.8 3 0 0 3 3 3 0 Fungal mating-type pheromone DUF4131 PF13567.1 EME77128.1 - 1.6 8.0 5.5 3.4 7.0 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SecA_DEAD PF07517.9 EME77130.1 - 0.014 14.7 0.0 0.014 14.6 0.0 1.0 1 0 0 1 1 1 0 SecA DEAD-like domain DUF390 PF04094.9 EME77131.1 - 0.00041 18.5 8.1 0.00053 18.1 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF390) DUF3552 PF12072.3 EME77131.1 - 0.009 15.2 13.7 0.009 15.2 9.5 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) CVNH PF08881.5 EME77131.1 - 0.45 10.7 3.4 0.36 11.0 0.4 2.2 2 0 0 2 2 2 0 CVNH domain DUF4200 PF13863.1 EME77131.1 - 7.5 6.5 34.4 1.6 8.6 10.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) PRKCSH-like PF12999.2 EME77131.1 - 7.7 6.0 7.9 7.1 6.1 4.4 1.8 1 1 1 2 2 2 0 Glucosidase II beta subunit-like ATG16 PF08614.6 EME77136.1 - 2.1e-05 24.4 2.7 2.1e-05 24.4 1.9 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EME77136.1 - 0.43 9.9 19.1 7.3 5.9 13.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Atg14 PF10186.4 EME77136.1 - 0.47 9.3 16.2 0.72 8.7 11.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_BLRF2 PF05812.7 EME77136.1 - 0.86 9.4 13.3 0.14 12.0 1.9 2.6 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Cation_efflux PF01545.16 EME77137.1 - 0.011 14.8 6.6 0.02 14.0 4.6 1.4 1 1 0 1 1 1 0 Cation efflux family O-antigen_lig PF13425.1 EME77137.1 - 0.051 13.5 10.1 0.19 11.7 7.0 1.8 1 1 1 2 2 2 0 O-antigen ligase like membrane protein MFS_1 PF07690.11 EME77137.1 - 0.052 12.2 15.1 0.27 9.8 8.9 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily FA_hydroxylase PF04116.8 EME77137.1 - 0.76 10.2 4.9 79 3.6 3.4 2.2 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily CopD PF05425.8 EME77137.1 - 2.3 8.4 14.2 0.081 13.1 3.1 2.3 1 1 1 2 2 2 0 Copper resistance protein D DUF605 PF04652.11 EME77140.1 - 1.7 7.9 14.4 2.7 7.3 10.0 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EME77140.1 - 3.5 5.7 11.0 4.6 5.3 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EME77140.1 - 5.6 6.7 6.9 8 6.2 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyclin PF08613.6 EME77147.1 - 2.6e-05 24.6 0.4 6.2e-05 23.4 0.3 1.9 1 1 0 1 1 1 1 Cyclin DAG_kinase_N PF14513.1 EME77149.1 - 0.082 13.0 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Toxin_67 PF15545.1 EME77149.1 - 0.088 12.6 1.4 0.13 12.1 0.2 1.8 2 0 0 2 2 2 0 Putative toxin 67 Peptidase_C48 PF02902.14 EME77150.1 - 0.00026 20.6 0.1 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Paf1 PF03985.8 EME77150.1 - 0.83 8.3 10.3 1.4 7.5 7.2 1.3 1 0 0 1 1 1 0 Paf1 HC2 PF07382.6 EME77152.1 - 0.00023 21.1 8.9 0.00051 19.9 6.2 1.5 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF3037 PF11236.3 EME77152.1 - 0.047 13.7 1.1 7.6 6.6 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3037) Calpain_inhib PF00748.14 EME77158.1 - 0.12 12.6 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 Calpain inhibitor zf-RING_2 PF13639.1 EME77159.1 - 8.1e-06 25.5 7.7 3.1e-05 23.6 2.2 2.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.1 EME77159.1 - 0.0049 16.5 1.1 0.0049 16.5 0.7 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 PHD PF00628.24 EME77159.1 - 0.014 15.0 2.8 0.014 15.0 1.9 3.6 4 0 0 4 4 4 0 PHD-finger Dynactin_p62 PF05502.8 EME77159.1 - 0.014 14.1 1.2 2.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Dynactin p62 family FANCL_C PF11793.3 EME77159.1 - 0.73 9.8 9.9 1.9 8.5 0.8 3.4 3 0 0 3 3 3 0 FANCL C-terminal domain Lar_restr_allev PF14354.1 EME77159.1 - 1.1 9.5 14.1 2.6 8.4 0.1 3.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar ATG16 PF08614.6 EME77161.1 - 0.0018 18.1 29.7 0.012 15.4 4.3 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CAP_N PF01213.14 EME77161.1 - 0.0027 17.0 0.9 0.0027 17.0 0.6 1.7 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal Fib_alpha PF08702.5 EME77161.1 - 0.012 15.7 11.0 0.012 15.7 7.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phi_1 PF04674.7 EME77161.1 - 0.11 11.6 1.4 0.13 11.3 0.0 1.8 2 1 0 2 2 2 0 Phosphate-induced protein 1 conserved region TMCO5 PF14992.1 EME77161.1 - 0.27 10.3 27.3 0.95 8.5 4.7 2.2 1 1 1 2 2 2 0 TMCO5 family Reo_sigmaC PF04582.7 EME77161.1 - 0.3 10.2 3.6 0.61 9.1 1.2 1.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 EME77161.1 - 0.36 10.3 29.9 0.034 13.7 4.4 2.2 1 1 1 2 2 2 0 IncA protein DUF948 PF06103.6 EME77161.1 - 0.38 10.6 3.9 11 5.9 0.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EME77161.1 - 0.84 8.0 26.2 1 7.7 17.1 1.8 1 1 1 2 2 2 0 AAA domain TMPIT PF07851.8 EME77161.1 - 1 8.3 12.8 1.3 8.0 4.9 2.2 1 1 1 2 2 2 0 TMPIT-like protein CALCOCO1 PF07888.6 EME77161.1 - 3.5 5.7 24.3 1.8e+02 0.1 16.9 2.1 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FemAB PF02388.11 EME77161.1 - 5.2 5.6 14.0 5.7 5.5 0.2 2.2 2 0 0 2 2 2 0 FemAB family Prominin PF05478.6 EME77161.1 - 7.9 3.8 12.8 32 1.8 8.2 2.1 1 1 1 2 2 2 0 Prominin Serglycin PF04360.7 EME77164.1 - 0.039 13.6 2.3 0.045 13.4 0.7 1.7 2 0 0 2 2 2 0 Serglycin Rota_NSP4 PF01452.11 EME77173.1 - 0.042 13.1 3.1 1.7 7.9 0.9 2.4 2 0 0 2 2 2 0 Rotavirus non structural protein Ribosomal_60s PF00428.14 EME77179.1 - 0.91 9.9 4.8 2 8.8 3.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Herpes_Helicase PF02689.9 EME77180.1 - 0.005 14.6 0.0 0.005 14.6 0.0 1.0 1 0 0 1 1 1 1 Helicase GpcrRhopsn4 PF10192.4 EME77180.1 - 0.032 13.4 0.0 0.035 13.3 0.0 1.0 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain U-box PF04564.10 EME77187.1 - 0.036 14.0 0.9 0.071 13.0 0.6 1.5 1 1 0 1 1 1 0 U-box domain BSMAP PF12280.3 EME77187.1 - 0.044 13.6 2.0 0.05 13.4 1.4 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein DER1 PF04511.10 EME77194.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Der1-like family DEAD PF00270.24 EME77197.1 - 0.00022 20.7 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase YGGT PF02325.12 EME77203.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 YGGT family DUF3408 PF11888.3 EME77206.1 - 0.076 12.9 1.6 0.14 12.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Reo_sigmaC PF04582.7 EME77211.1 - 2.7 7.0 12.4 4.6 6.3 1.4 3.4 1 1 4 5 5 5 0 Reovirus sigma C capsid protein IncA PF04156.9 EME77211.1 - 4.6 6.7 49.3 5 6.6 7.8 3.9 1 1 2 3 3 3 0 IncA protein DUF3584 PF12128.3 EME77211.1 - 6.5 3.9 50.0 0.045 11.0 12.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Viral_DNA_bp PF00747.12 EME77212.1 - 0.15 9.2 1.2 0.22 8.7 0.8 1.1 1 0 0 1 1 1 0 ssDNA binding protein DUF342 PF03961.8 EME77212.1 - 0.22 9.8 3.6 0.36 9.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4071 PF13281.1 EME77212.1 - 1.6 7.4 8.5 0.36 9.6 3.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) adh_short PF00106.20 EME77216.1 - 4.5e-29 101.5 0.1 7.2e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME77216.1 - 2e-16 60.4 0.0 2.6e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME77216.1 - 4.8e-13 49.1 0.1 7e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME77216.1 - 0.00023 21.2 0.1 0.00041 20.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding PP2C_2 PF13672.1 EME77216.1 - 0.014 14.7 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Epimerase PF01370.16 EME77216.1 - 0.042 13.2 0.0 0.34 10.3 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBFD_NFYB_HMF PF00808.18 EME77217.1 - 1.6e-13 50.4 3.9 9.8e-13 47.9 2.7 2.0 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME77217.1 - 0.052 13.6 0.1 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EME77217.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Peptidase_S10 PF00450.17 EME77218.1 - 1.6e-80 271.3 0.0 2.1e-80 270.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EME77218.1 - 1.2e-05 25.3 0.0 0.00036 20.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME77218.1 - 0.059 12.5 0.4 0.18 11.0 0.0 1.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family GST_N_3 PF13417.1 EME77220.1 - 3.8e-14 52.6 0.1 6.7e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME77220.1 - 4.7e-12 45.7 0.1 7.6e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME77220.1 - 6.4e-12 45.2 0.1 1.6e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME77220.1 - 1.8e-10 40.8 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME77220.1 - 3.8e-08 33.1 0.4 1.3e-07 31.3 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME77220.1 - 0.0027 18.1 0.1 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NOPS PF08075.6 EME77220.1 - 0.081 13.3 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 NOPS (NUC059) domain Tfb2 PF03849.9 EME77221.1 - 6.1e-126 419.9 5.7 1.3e-124 415.5 1.9 2.7 2 1 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EME77221.1 - 7.1e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box PF00646.28 EME77223.1 - 1.7e-07 30.7 0.0 3.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME77223.1 - 0.00024 20.7 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like Pro_3_hydrox_C PF05373.6 EME77223.1 - 0.018 15.0 0.1 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal MFS_1 PF07690.11 EME77224.1 - 1.6e-20 73.1 80.2 4e-16 58.6 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-H2C2_2 PF13465.1 EME77227.1 - 2.2e-09 37.1 11.0 2.7e-06 27.3 1.0 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME77227.1 - 2.3e-09 36.9 2.9 0.00049 20.2 0.3 2.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME77227.1 - 1.7e-08 34.3 7.1 5e-05 23.4 0.6 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EME77227.1 - 0.44 10.7 2.1 7.2 6.8 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CCHC_5 PF14787.1 EME77227.1 - 1.3 8.6 7.3 0.14 11.6 1.7 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Zn-ribbon_8 PF09723.5 EME77227.1 - 1.4 8.9 4.3 6.4 6.8 0.3 2.2 1 1 0 2 2 2 0 Zinc ribbon domain HEAT_2 PF13646.1 EME77228.1 - 0.0032 17.7 1.9 0.38 11.0 0.1 2.9 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EME77228.1 - 0.14 12.3 0.9 5.5 7.3 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat Actin PF00022.14 EME77229.1 - 7.2e-87 291.3 0.0 8.5e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME77229.1 - 0.0021 16.7 0.0 0.28 9.7 0.0 2.6 3 0 0 3 3 3 2 MreB/Mbl protein Acyl_transf_1 PF00698.16 EME77230.1 - 1.8e-81 273.9 0.0 9.6e-81 271.5 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EME77230.1 - 1.9e-37 127.3 0.0 4.5e-37 126.1 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EME77230.1 - 4.1e-31 106.5 0.7 6.3e-30 102.7 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EME77230.1 - 2.8e-21 75.6 0.1 9.7e-21 73.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EME77230.1 - 0.00085 18.5 0.2 0.27 10.3 0.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase Phi-29_GP3 PF05435.6 EME77230.1 - 0.024 13.8 0.0 0.059 12.5 0.0 1.6 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 ketoacyl-synt PF00109.21 EME77231.1 - 7.8e-19 68.1 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EME77231.1 - 1.1e-18 67.9 0.0 1.9e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EME77231.1 - 2.6e-16 59.4 0.0 6.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EME77231.1 - 2.5e-10 40.2 0.0 5.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EME77231.1 - 3e-07 30.5 0.0 5.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME77231.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain IncA PF04156.9 EME77231.1 - 0.077 12.5 2.8 0.25 10.9 2.0 1.8 1 0 0 1 1 1 0 IncA protein Brr6_like_C_C PF10104.4 EME77232.1 - 1.3e-45 154.1 0.1 1.9e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Luteo_Vpg PF01659.11 EME77232.1 - 0.01 15.5 2.5 0.034 13.8 1.7 1.9 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein MFS_1 PF07690.11 EME77233.1 - 1.2e-24 86.6 78.0 2.3e-23 82.4 37.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TIMELESS PF04821.9 EME77235.1 - 1.4e-90 303.2 0.7 1.4e-90 303.2 0.5 2.4 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 EME77235.1 - 7.7e-29 101.0 10.0 7.7e-29 101.0 6.9 3.7 2 1 1 3 3 3 1 Timeless protein C terminal region APOBEC_N PF08210.6 EME77235.1 - 0.012 15.2 0.5 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 APOBEC-like N-terminal domain 3HCDH_N PF02737.13 EME77236.1 - 2.1e-56 190.4 0.8 2.9e-56 189.9 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EME77236.1 - 1.5e-32 111.8 0.0 3.5e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EME77236.1 - 0.001 18.9 0.4 0.002 17.9 0.3 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME77236.1 - 0.0014 18.3 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EME77236.1 - 0.0031 16.6 0.2 0.006 15.7 0.0 1.5 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EME77236.1 - 0.0039 17.5 0.1 0.0086 16.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME77236.1 - 0.0045 15.9 1.2 0.0083 15.0 0.8 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.12 EME77236.1 - 0.014 15.7 1.7 0.062 13.7 0.3 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.9 EME77236.1 - 0.048 13.5 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EME77236.1 - 0.084 12.2 0.3 0.31 10.4 0.1 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 EME77236.1 - 0.21 11.6 1.5 0.56 10.2 1.0 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME77239.1 - 4.8e-98 328.2 0.0 6.1e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME77239.1 - 1.2e-08 34.8 0.6 3.1e-08 33.5 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME77239.1 - 9.7e-07 29.0 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME77239.1 - 2e-05 24.5 0.0 0.0002 21.3 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME77239.1 - 0.11 11.4 0.9 0.24 10.2 0.6 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase ABC_membrane PF00664.18 EME77240.1 - 1.2e-65 221.6 29.4 1.6e-34 119.6 10.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME77240.1 - 2.1e-63 212.6 0.0 1.4e-32 112.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME77240.1 - 4.7e-13 49.7 0.0 0.0047 16.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EME77240.1 - 1.5e-10 40.7 0.1 0.006 15.8 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EME77240.1 - 1.3e-07 30.5 0.6 0.0087 14.6 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EME77240.1 - 2.3e-06 27.0 1.0 0.046 13.2 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EME77240.1 - 4.7e-05 22.6 0.0 0.14 11.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME77240.1 - 0.0001 22.1 2.1 0.58 10.1 0.1 3.9 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EME77240.1 - 0.00012 21.6 0.3 0.1 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 EME77240.1 - 0.00012 21.5 0.3 0.79 9.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EME77240.1 - 0.00028 21.0 0.2 1.8 8.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME77240.1 - 0.00067 20.4 0.0 1 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME77240.1 - 0.0067 16.4 3.9 3.5 7.5 0.8 4.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 EME77240.1 - 0.011 16.0 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EME77240.1 - 0.02 13.9 0.0 0.51 9.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EME77240.1 - 0.025 14.4 0.0 10 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EME77240.1 - 0.03 14.0 0.2 8.2 6.1 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EME77240.1 - 0.25 11.1 3.5 3.1 7.5 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AMP-binding PF00501.23 EME77241.1 - 3.5e-244 809.6 0.0 2.6e-91 306.0 0.0 3.7 4 0 0 4 4 4 3 AMP-binding enzyme Condensation PF00668.15 EME77241.1 - 1.8e-182 604.9 5.7 8.9e-32 110.1 0.5 7.4 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EME77241.1 - 6.4e-56 186.5 15.6 6.6e-10 39.1 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EME77241.1 - 7.2e-21 74.9 0.0 2.6e-06 28.2 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EME77241.1 - 1.1e-06 27.4 0.0 0.45 8.8 0.0 4.5 5 0 0 5 5 5 3 Transferase family Amidohydro_4 PF13147.1 EME77242.1 - 4.7e-10 39.9 0.1 1.5e-08 35.0 0.1 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EME77242.1 - 2.2e-09 37.4 0.0 4.2e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EME77242.1 - 1.1e-06 28.3 0.0 3.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME77242.1 - 6.5e-06 25.6 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Glyco_hydro_3 PF00933.16 EME77243.1 - 2.7e-56 190.7 0.0 3.8e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EME77243.1 - 1.4e-05 25.0 0.0 9.8e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 EME77243.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 EME77243.1 - 0.015 15.4 0.0 0.054 13.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EME77243.1 - 0.14 12.1 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA PF00004.24 EME77244.1 - 2.6e-17 63.2 0.0 3.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME77244.1 - 0.00015 21.9 0.0 0.0003 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME77244.1 - 0.024 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME77244.1 - 0.03 15.1 0.0 0.056 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME77244.1 - 0.031 13.3 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EME77244.1 - 0.037 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein HET PF06985.6 EME77245.1 - 1.7e-23 83.2 5.3 1.7e-20 73.5 0.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box PF00646.28 EME77247.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 F-box domain CFEM PF05730.6 EME77248.1 - 4.5e-05 23.1 0.6 4.5e-05 23.1 0.4 3.2 4 0 0 4 4 4 1 CFEM domain Pribosyltran PF00156.22 EME77250.1 - 6.3e-09 35.6 0.1 1.5e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.20 EME77254.1 - 5.8e-58 196.0 0.0 7e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77254.1 - 9.7e-32 110.0 0.0 1.1e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME77254.1 - 0.0043 16.0 0.0 0.0098 14.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME77254.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EME77254.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EME77254.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EME77256.1 - 1.3e-56 191.6 0.0 1.9e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77256.1 - 3e-25 88.7 0.1 7.2e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EME77256.1 - 6.6e-05 22.7 0.0 0.00045 20.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EME77256.1 - 0.004 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EME77256.1 - 0.009 15.3 1.0 0.18 11.1 0.7 2.2 1 1 0 1 1 1 1 RIO1 family Defensin_2 PF01097.13 EME77257.1 - 0.046 13.4 4.4 0.64 9.7 0.1 2.7 2 0 0 2 2 2 0 Arthropod defensin Alpha-amylase PF00128.19 EME77258.1 - 1.4e-31 110.1 2.9 2.9e-31 109.0 2.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EME77258.1 - 0.0061 14.4 1.1 0.43 8.2 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 Ldh_2 PF02615.9 EME77259.1 - 1.2e-101 339.8 0.1 1.3e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ILVD_EDD PF00920.16 EME77261.1 - 1.5e-154 515.3 0.0 1.7e-154 515.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Acyl-CoA_dh_1 PF00441.19 EME77262.1 - 3e-23 82.5 0.9 5.1e-23 81.8 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME77262.1 - 9.4e-14 51.9 0.0 2.4e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME77262.1 - 4.9e-07 30.0 0.1 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME77262.1 - 1.4e-05 24.5 0.0 3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Abhydrolase_3 PF07859.8 EME77263.1 - 5.5e-49 166.6 0.0 7.1e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME77263.1 - 6.1e-13 48.3 0.1 1.4e-12 47.0 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EME77263.1 - 0.00011 22.0 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME77263.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NAD_binding_10 PF13460.1 EME77264.1 - 0.029 14.3 0.0 0.27 11.2 0.0 2.4 2 1 0 2 2 2 0 NADH(P)-binding APH PF01636.18 EME77265.1 - 1.4e-36 126.4 0.0 2.2e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EME77265.1 - 3.8e-06 26.2 0.0 5.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EME77265.1 - 1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EME77265.1 - 0.00016 21.0 0.0 0.0027 17.0 0.0 2.3 2 1 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 EME77265.1 - 0.0063 15.2 0.0 0.01 14.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EME77265.1 - 0.041 12.8 0.0 0.57 9.0 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase Kdo PF06293.9 EME77265.1 - 0.077 12.0 0.1 0.34 9.9 0.0 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 EME77267.1 - 2.2e-70 237.4 0.0 3e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EME77268.1 - 6e-85 285.1 0.0 7.4e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME77268.1 - 6.6e-10 39.7 0.1 2.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EME77269.1 - 1.6e-27 96.4 1.5 2.1e-27 96.0 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME77269.1 - 2.2e-27 96.3 0.0 2.7e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME77269.1 - 2.1e-14 53.5 0.4 2.9e-14 53.1 0.3 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME77269.1 - 0.098 12.4 0.8 0.23 11.2 0.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Tup_N PF08581.5 EME77270.1 - 0.018 15.2 0.2 0.035 14.2 0.1 1.4 1 0 0 1 1 1 0 Tup N-terminal EthD PF07110.6 EME77271.1 - 0.023 15.6 0.1 2.1 9.3 0.0 2.3 2 0 0 2 2 2 0 EthD domain DUF4286 PF14114.1 EME77271.1 - 0.037 14.2 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) EthD PF07110.6 EME77272.1 - 2.3e-10 41.2 1.6 1.2e-09 38.9 1.1 1.9 1 1 0 1 1 1 1 EthD domain DUF1638 PF07796.6 EME77272.1 - 0.14 11.7 0.4 0.29 10.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1638) TRI12 PF06609.8 EME77273.1 - 6.4e-44 150.1 17.6 7.7e-44 149.8 12.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME77273.1 - 7.9e-20 70.8 34.6 7.9e-20 70.8 24.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME77273.1 - 2.2e-07 29.8 11.0 2.2e-07 29.8 7.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Aldedh PF00171.17 EME77274.1 - 8.2e-146 485.9 0.0 1.3e-145 485.3 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME77274.1 - 0.0012 18.1 0.0 0.013 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) adh_short PF00106.20 EME77275.1 - 5.1e-21 75.3 0.0 8.8e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME77275.1 - 3.2e-07 30.1 0.0 6.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME77275.1 - 0.0055 16.5 0.0 0.059 13.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME77275.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EME77275.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EME77276.1 - 9.1e-23 81.3 0.0 3.7e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME77276.1 - 1.4e-17 63.1 1.0 2.7e-15 55.5 0.1 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME77276.1 - 1.2e-10 41.2 0.0 3.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME77276.1 - 1.2e-08 34.3 0.0 4.3e-05 22.6 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME77276.1 - 1.9e-05 24.4 0.1 0.00015 21.5 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding mRNA_cap_C PF03919.10 EME77276.1 - 0.031 14.5 1.4 0.067 13.5 0.1 2.1 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain DUF3042 PF11240.3 EME77276.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DAO PF01266.19 EME77276.1 - 0.058 12.2 0.0 0.19 10.6 0.0 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EME77276.1 - 0.15 11.1 0.0 0.7 8.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.13 EME77278.1 - 1.2e-22 80.0 0.0 2.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME77278.1 - 0.00027 20.7 8.6 0.00051 19.8 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EME77279.1 - 3.7e-26 92.0 0.3 5.8e-26 91.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME77279.1 - 3.6e-19 69.4 0.6 7.9e-19 68.3 0.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME77279.1 - 9e-14 51.5 0.1 1.4e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EME77279.1 - 0.0008 19.2 0.1 0.0022 17.8 0.0 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EME77279.1 - 0.029 14.8 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME77279.1 - 0.079 12.3 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Epimerase PF01370.16 EME77279.1 - 0.086 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ThiF PF00899.16 EME77279.1 - 0.14 12.0 2.8 0.52 10.1 0.7 2.4 2 1 1 3 3 3 0 ThiF family Pyr_redox_3 PF13738.1 EME77280.1 - 4.3e-21 75.9 0.0 2e-20 73.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME77280.1 - 8.7e-12 44.0 0.3 5.1e-08 31.5 0.1 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME77280.1 - 6.9e-10 38.8 0.0 1.9e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME77280.1 - 6.4e-05 22.0 0.0 0.076 11.9 0.0 3.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME77280.1 - 0.00015 21.5 0.1 0.0012 18.6 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EME77280.1 - 0.004 16.2 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EME77280.1 - 0.055 11.9 0.0 0.087 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EME77280.1 - 0.097 11.5 0.0 0.2 10.5 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Herpes_capsid PF06112.6 EME77281.1 - 2.3 8.2 4.5 2.8 7.9 3.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Methyltransf_23 PF13489.1 EME77282.1 - 7e-17 61.6 0.0 1.2e-16 60.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME77282.1 - 0.00049 20.5 0.0 0.0043 17.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME77282.1 - 0.00062 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77282.1 - 0.0013 18.2 0.0 0.017 14.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME77282.1 - 0.0014 19.0 0.0 0.0075 16.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME77282.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Lipase_GDSL_3 PF14606.1 EME77282.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pox_MCEL PF03291.11 EME77282.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme zf-TAZ PF02135.11 EME77283.1 - 0.062 13.3 0.6 0.07 13.1 0.4 1.1 1 0 0 1 1 1 0 TAZ zinc finger DAO PF01266.19 EME77284.1 - 1e-48 166.1 0.1 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME77284.1 - 9.6e-07 28.6 0.1 0.041 13.6 0.0 2.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME77284.1 - 4e-06 26.7 0.0 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME77284.1 - 2.3e-05 24.3 0.3 0.026 14.4 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME77284.1 - 3.3e-05 22.9 0.3 0.00012 21.0 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME77284.1 - 7.3e-05 22.9 0.1 0.019 15.0 0.1 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME77284.1 - 9e-05 21.2 0.0 0.053 12.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EME77284.1 - 0.0024 18.2 0.2 0.24 11.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME77284.1 - 0.018 14.1 0.0 0.43 9.6 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EME77284.1 - 0.039 12.8 0.1 6.5 5.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Saccharop_dh PF03435.13 EME77284.1 - 0.052 12.5 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase p450 PF00067.17 EME77285.1 - 4.6e-77 259.4 0.0 6.1e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EME77285.1 - 8.4e-19 67.8 0.0 2.4e-15 56.5 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EME77285.1 - 1.5e-18 67.1 0.0 2.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EME77285.1 - 2.6e-15 56.9 0.0 7.1e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME77285.1 - 0.11 12.6 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Flavodoxin_5 PF12724.2 EME77285.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin domain RVT_2 PF07727.9 EME77287.1 - 1.6e-10 40.4 0.0 1.7e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dus PF01207.12 EME77290.1 - 5e-58 196.3 0.0 6.1e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) AAA_16 PF13191.1 EME77291.1 - 4.9e-10 39.6 0.2 4.9e-10 39.6 0.2 4.3 3 2 1 4 4 4 1 AAA ATPase domain NACHT PF05729.7 EME77291.1 - 1.2e-08 34.7 0.2 5.2e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EME77291.1 - 5.4e-06 26.5 0.0 5.4e-06 26.5 0.0 4.4 4 0 0 4 4 3 1 AAA domain TPR_12 PF13424.1 EME77291.1 - 6.6e-06 25.9 37.5 0.033 14.1 0.9 10.7 9 1 3 12 12 11 2 Tetratricopeptide repeat AAA_18 PF13238.1 EME77291.1 - 3.9e-05 23.9 0.1 0.0011 19.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EME77291.1 - 4.5e-05 23.6 0.0 0.0006 20.0 0.0 3.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME77291.1 - 9.4e-05 23.2 0.0 0.00061 20.5 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME77291.1 - 0.00081 19.2 0.2 0.0079 16.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME77291.1 - 0.0036 17.0 0.0 0.015 15.0 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EME77291.1 - 0.0044 16.7 0.1 0.03 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TPR_6 PF13174.1 EME77291.1 - 0.0075 16.6 9.0 16 6.2 0.1 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat SRP54 PF00448.17 EME77291.1 - 0.0084 15.5 0.1 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EME77291.1 - 0.012 15.0 1.7 0.056 12.8 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME77291.1 - 0.022 14.6 0.2 0.28 11.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME77291.1 - 0.026 14.6 0.0 0.12 12.5 0.0 2.2 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EME77291.1 - 0.31 11.3 5.0 0.59 10.4 0.0 3.6 2 1 1 3 3 3 0 ABC transporter TPR_16 PF13432.1 EME77291.1 - 0.74 10.5 14.7 0.62 10.7 0.6 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME77291.1 - 0.77 9.7 14.7 6 6.9 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME77291.1 - 1.2 9.4 15.8 8.3 6.8 0.0 7.3 9 1 0 9 9 7 0 Tetratricopeptide repeat MFS_1 PF07690.11 EME77292.1 - 1.1e-08 34.1 5.9 1.1e-08 34.1 4.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily B12-binding PF02310.14 EME77293.1 - 0.078 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain DUF3500 PF12006.3 EME77294.1 - 1.9e-94 316.1 0.0 2.3e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Methyltransf_23 PF13489.1 EME77295.1 - 3.7e-09 36.5 0.0 1e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77295.1 - 3.7e-06 26.6 0.0 1.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME77295.1 - 0.00056 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME77295.1 - 0.0027 18.1 0.0 0.0057 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HsbA PF12296.3 EME77296.1 - 3.1e-19 69.0 9.2 4.8e-19 68.4 6.3 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF3700 PF12481.3 EME77296.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein Methyltransf_2 PF00891.13 EME77297.1 - 1.9e-18 66.5 0.5 2.5e-14 53.0 0.0 2.9 3 0 0 3 3 3 2 O-methyltransferase Transp_cyt_pur PF02133.10 EME77298.1 - 2.6e-08 32.8 5.8 4.2e-08 32.1 4.0 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Borealin PF10512.4 EME77299.1 - 0.0069 16.2 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Chitin_bind_3 PF03067.10 EME77300.1 - 2e-08 34.7 1.8 5.6e-08 33.2 1.2 1.6 1 1 0 1 1 1 1 Chitin binding domain SET PF00856.23 EME77301.1 - 3e-14 53.6 0.1 4e-13 49.9 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EME77301.1 - 3.1e-09 36.5 10.4 3.1e-09 36.5 7.2 2.3 2 0 0 2 2 2 1 MYND finger POTRA_1 PF08478.5 EME77301.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, FtsQ-type Peptidase_S10 PF00450.17 EME77302.1 - 2.9e-90 303.4 2.6 4.4e-90 302.8 1.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase PAF-AH_p_II PF03403.8 EME77303.1 - 1e-38 132.6 0.0 1.7e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EME77303.1 - 3.1e-10 39.9 0.1 9.4e-10 38.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME77303.1 - 0.00013 21.9 0.2 0.0004 20.3 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME77303.1 - 0.00039 19.3 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EME77303.1 - 0.02 14.4 0.0 0.068 12.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EME77303.1 - 0.11 11.2 0.0 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase DUF1815 PF08844.5 EME77304.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1815) ECH PF00378.15 EME77305.1 - 3.9e-42 144.0 0.1 4.8e-42 143.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HAD_2 PF13419.1 EME77306.1 - 4.9e-14 52.9 0.0 7.2e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME77306.1 - 7.2e-07 28.8 0.0 2.1e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EME77306.1 - 0.0023 18.3 0.0 0.0098 16.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF837 PF05769.6 EME77307.1 - 0.082 12.4 0.2 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Apolipoprotein PF01442.13 EME77308.1 - 6.3e-05 22.5 12.9 0.048 13.1 4.1 3.7 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain XH PF03469.9 EME77308.1 - 0.014 15.0 10.2 0.22 11.1 1.5 3.8 2 1 2 4 4 4 0 XH domain AIF-MLS PF14962.1 EME77308.1 - 0.016 14.8 0.7 6 6.4 0.1 2.5 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Sec15 PF04091.7 EME77308.1 - 0.022 14.1 0.2 0.05 12.9 0.1 1.6 1 1 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF883 PF05957.8 EME77308.1 - 0.028 14.7 15.2 4.5 7.7 0.0 5.4 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF883) ApbA_C PF08546.6 EME77308.1 - 0.045 13.7 0.3 10 6.1 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal MCPsignal PF00015.16 EME77308.1 - 0.055 13.0 6.2 1.9 7.9 0.1 3.4 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Uteroglobin PF01099.12 EME77308.1 - 2 8.2 10.9 7.1 6.5 0.0 4.7 5 0 0 5 5 5 0 Uteroglobin family DUF2203 PF09969.4 EME77308.1 - 2.5 8.3 9.0 0.82 9.8 0.1 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) MxiH PF09392.5 EME77308.1 - 3.2 8.3 10.9 2e+02 2.6 4.1 4.1 2 1 0 2 2 2 0 Type III secretion needle MxiH like Elongin_A PF06881.6 EME77308.1 - 7 7.0 8.1 1.6 9.1 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Prominin PF05478.6 EME77308.1 - 7.3 3.9 6.3 59 0.9 3.1 2.9 2 1 0 2 2 2 0 Prominin FliT PF05400.8 EME77308.1 - 7.6 7.0 9.5 0.29 11.5 0.2 3.1 3 1 0 3 3 3 0 Flagellar protein FliT MRFAP1 PF15155.1 EME77309.1 - 0.025 14.9 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 MORF4 family-associated protein1 Ovate PF04844.8 EME77309.1 - 0.16 11.7 0.7 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 Transcriptional repressor, ovate FAD_binding_3 PF01494.14 EME77310.1 - 1.7e-17 63.5 1.2 3.2e-16 59.3 0.8 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME77310.1 - 2.2e-06 26.8 0.5 0.0047 15.8 0.1 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME77310.1 - 0.00012 22.0 0.1 0.00066 19.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME77310.1 - 0.004 16.0 0.2 0.0068 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EME77310.1 - 0.004 16.0 0.0 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 EME77310.1 - 0.0069 16.7 0.1 0.019 15.3 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME77310.1 - 0.0082 16.2 0.1 0.036 14.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME77310.1 - 0.056 13.2 0.2 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Hist_deacetyl PF00850.14 EME77310.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Histone deacetylase domain Fungal_trans PF04082.13 EME77312.1 - 3.6e-25 88.3 1.0 4.5e-25 88.0 0.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain cNMP_binding PF00027.24 EME77313.1 - 1.1e-34 118.0 0.0 4.7e-17 61.5 0.0 4.4 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EME77313.1 - 4e-16 59.5 6.1 1e-14 54.9 4.2 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase Paf1 PF03985.8 EME77314.1 - 1e-38 133.2 0.0 2.3e-37 128.7 0.0 2.1 1 1 0 1 1 1 1 Paf1 RecR PF02132.10 EME77316.1 - 0.3 10.5 3.5 1.6 8.1 0.3 2.6 2 0 0 2 2 2 0 RecR protein zf-Apc11 PF12861.2 EME77316.1 - 0.34 10.7 3.6 0.91 9.4 0.7 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DHquinase_II PF01220.14 EME77318.1 - 4.1e-61 204.3 0.0 4.7e-61 204.2 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Dioxygenase_C PF00775.16 EME77319.1 - 2.6e-51 173.4 0.0 3.4e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EME77319.1 - 2.2e-17 62.7 0.0 4.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EME77319.1 - 0.022 14.7 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain WIYLD PF10440.4 EME77319.1 - 0.044 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain F-box-like PF12937.2 EME77320.1 - 0.096 12.4 0.9 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 F-box-like adh_short PF00106.20 EME77321.1 - 2.7e-23 82.6 0.3 3.5e-23 82.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME77321.1 - 6.5e-20 71.9 0.0 7.7e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME77321.1 - 2.4e-10 40.3 0.2 3.2e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME77321.1 - 0.00021 20.7 0.1 0.0007 19.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME77321.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-RanBP PF00641.13 EME77322.1 - 0.57 9.3 2.8 3.8 6.7 0.6 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RCC1 PF00415.13 EME77327.1 - 1.9e-49 165.6 6.5 1.2e-09 38.1 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME77327.1 - 2.3e-37 125.8 20.3 8.2e-10 38.0 0.1 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF3445 PF11927.3 EME77328.1 - 3.5e-71 239.5 0.0 4.3e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) BTB PF00651.26 EME77330.1 - 0.0039 17.1 0.1 0.02 14.8 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 EME77331.1 - 1.5e-28 99.5 48.0 1.3e-26 93.1 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EME77331.1 - 0.033 14.1 0.8 0.033 14.1 0.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Cyclase PF04199.8 EME77332.1 - 2.8e-08 33.6 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Metallophos PF00149.23 EME77333.1 - 8.2e-08 31.8 1.2 2.1e-07 30.5 0.9 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME77333.1 - 4.8e-05 23.2 0.0 9.1e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RolB_RolC PF02027.12 EME77336.1 - 0.011 14.9 0.9 2 7.5 0.1 2.6 1 1 1 2 2 2 0 RolB/RolC glucosidase family RHH_3 PF12651.2 EME77336.1 - 1.6 8.5 7.0 64 3.3 0.0 4.0 4 0 0 4 4 4 0 Ribbon-helix-helix domain MFS_1 PF07690.11 EME77337.1 - 9.8e-20 70.5 36.8 9.8e-20 70.5 25.5 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME77337.1 - 1.5e-06 27.1 14.3 1.5e-06 27.1 9.9 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter B12D PF06522.6 EME77337.1 - 0.65 9.7 0.0 0.65 9.7 0.0 3.1 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribonucleas_3_3 PF14622.1 EME77338.1 - 3.4e-11 43.2 0.0 4.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EME77338.1 - 3.1e-09 37.2 0.0 1.1e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain eIF-3c_N PF05470.7 EME77340.1 - 4.7e-170 566.5 24.5 8.5e-140 466.6 3.6 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EME77340.1 - 2.2e-12 47.2 4.0 8.7e-12 45.2 0.0 3.7 4 0 0 4 4 4 1 PCI domain U1snRNP70_N PF12220.3 EME77340.1 - 0.032 14.5 0.7 0.032 14.5 0.5 3.2 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ferric_reduct PF01794.14 EME77341.1 - 3.2e-16 59.5 11.3 6.4e-16 58.5 7.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EME77341.1 - 5.3e-11 42.6 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EME77341.1 - 4.4e-10 39.3 0.1 8.1e-09 35.3 0.0 2.7 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_1 PF00175.16 EME77341.1 - 4.9e-05 23.8 0.0 7.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME77341.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain zf-H2C2_5 PF13909.1 EME77342.1 - 0.0003 20.8 33.5 0.16 12.2 0.5 7.1 6 0 0 6 6 6 3 C2H2-type zinc-finger domain Remorin_C PF03763.8 EME77342.1 - 0.5 9.9 2.8 6.2 6.3 0.0 3.3 4 0 0 4 4 4 0 Remorin, C-terminal region Glyco_transf_90 PF05686.7 EME77345.1 - 8.7e-20 70.7 0.1 1.3e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 FMO-like PF00743.14 EME77346.1 - 1.9e-28 99.0 0.0 1e-19 70.1 0.0 2.0 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME77346.1 - 4.8e-16 59.4 0.0 7.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME77346.1 - 2.3e-11 43.9 0.0 7.6e-11 42.2 0.0 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME77346.1 - 1.4e-10 41.0 0.0 3.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME77346.1 - 4.3e-09 35.8 0.6 5.2e-08 32.2 0.1 2.5 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EME77346.1 - 2.5e-07 29.9 0.0 3.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME77346.1 - 2.4e-06 26.6 0.2 3.8e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME77346.1 - 5e-06 26.8 0.1 2.4e-05 24.6 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME77346.1 - 1.2e-05 24.6 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME77346.1 - 2.3e-05 24.2 4.3 0.0004 20.1 2.3 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EME77346.1 - 2.3e-05 23.6 0.1 4.8e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME77346.1 - 6.1e-05 21.6 1.2 0.00015 20.4 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 EME77346.1 - 0.00016 20.8 0.0 0.00056 19.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EME77346.1 - 0.00022 20.2 0.0 0.00048 19.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EME77346.1 - 0.0015 17.5 0.0 0.0038 16.1 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EME77346.1 - 0.024 13.3 0.7 0.17 10.5 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Strep_67kDa_ant PF06100.6 EME77346.1 - 0.11 10.8 0.1 0.22 9.8 0.0 1.5 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family 3HCDH_N PF02737.13 EME77346.1 - 0.19 11.3 0.2 0.38 10.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PfkB PF00294.19 EME77347.1 - 5.4e-10 38.8 0.1 8.1e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NDT80_PhoG PF05224.7 EME77352.1 - 5.2e-33 114.6 0.0 8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family FAD_binding_3 PF01494.14 EME77353.1 - 7.3e-09 35.1 0.0 8.2e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Hexokinase_1 PF00349.16 EME77354.1 - 2e-36 125.2 0.0 3.1e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EME77354.1 - 3.7e-34 118.0 0.0 5.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase UNC-93 PF05978.11 EME77355.1 - 1.2e-14 54.1 7.8 1.2e-14 54.1 5.4 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EME77355.1 - 4.7e-09 35.4 33.8 4.7e-09 35.4 23.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glucosamine_iso PF01182.15 EME77356.1 - 9.4e-23 80.9 0.0 1.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ATG22 PF11700.3 EME77357.1 - 3.4e-121 405.0 29.9 4.1e-119 398.1 20.8 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EME77357.1 - 8.4e-08 31.3 36.5 8e-05 21.5 6.5 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Aa_trans PF01490.13 EME77359.1 - 6e-38 130.3 33.0 7.2e-38 130.1 22.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EME77359.1 - 4.1 5.9 28.8 0.41 9.2 14.5 2.8 2 1 0 2 2 2 0 Spore germination protein peroxidase PF00141.18 EME77360.1 - 1.6e-24 86.6 0.0 2.9e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ABC1 PF03109.11 EME77360.1 - 1.2e-22 80.1 0.0 1.3e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EME77360.1 - 0.026 14.2 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Intg_mem_TP0381 PF09529.5 EME77360.1 - 0.08 12.1 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Zn_Tnp_IS1595 PF12760.2 EME77362.1 - 0.011 15.5 1.3 0.024 14.4 0.9 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF3632 PF12311.3 EME77363.1 - 9e-11 41.9 0.8 1.4e-10 41.3 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Lenti_VIF_2 PF07401.7 EME77363.1 - 0.043 12.9 0.0 0.095 11.8 0.0 1.5 1 0 0 1 1 1 0 Bovine Lentivirus VIF protein MFS_1 PF07690.11 EME77364.1 - 3.2e-12 45.8 38.0 4.6e-12 45.3 26.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EME77364.1 - 4.6e-06 26.2 6.1 4.6e-06 26.2 4.3 2.5 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EME77365.1 - 1.4e-23 83.2 37.3 2.5e-13 49.5 8.1 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF950 PF06106.6 EME77365.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) Aldo_ket_red PF00248.16 EME77366.1 - 6.9e-54 182.5 0.0 8.1e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tox-GHH PF15636.1 EME77366.1 - 0.12 12.0 0.1 0.55 9.9 0.0 2.1 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Bestrophin PF01062.16 EME77367.1 - 2e-51 174.6 0.8 2.8e-50 170.9 0.5 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DnaJ PF00226.26 EME77369.1 - 2.1e-18 65.7 0.3 2.3e-18 65.6 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain LRR_4 PF12799.2 EME77372.1 - 1.1e-39 133.3 46.0 3.6e-08 32.8 0.1 11.0 5 3 5 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME77372.1 - 1.1e-34 117.9 50.1 1.5e-08 34.2 0.2 9.3 4 2 5 10 10 10 9 Leucine rich repeat LRR_1 PF00560.28 EME77372.1 - 6.4e-22 74.2 44.5 0.069 13.2 0.0 16.6 18 1 1 19 19 19 6 Leucine Rich Repeat LRR_7 PF13504.1 EME77372.1 - 6.9e-15 52.5 46.4 0.045 13.9 0.2 15.7 17 0 0 17 17 17 5 Leucine rich repeat LRR_6 PF13516.1 EME77372.1 - 3.7e-08 32.6 48.7 1.8 8.8 0.2 14.8 16 2 2 18 18 18 4 Leucine Rich repeat LRR_9 PF14580.1 EME77372.1 - 0.091 12.3 13.1 3.5 7.1 0.8 4.6 2 2 2 5 5 5 0 Leucine-rich repeat F-box PF00646.28 EME77373.1 - 7.8e-08 31.7 0.4 1.5e-07 30.8 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME77373.1 - 4.3e-05 23.1 0.3 8.4e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like YcbB PF08664.5 EME77374.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 YcbB domain DAO PF01266.19 EME77375.1 - 1.1e-38 133.1 0.0 1.6e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EME77375.1 - 1.2e-07 30.7 0.0 0.00063 18.4 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 EME77375.1 - 8.8e-07 28.8 0.0 0.0091 15.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME77375.1 - 2.6e-05 24.2 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME77375.1 - 0.00055 19.9 0.0 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME77375.1 - 0.0091 16.3 0.0 0.41 11.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME77375.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EME77375.1 - 0.017 14.0 0.0 0.19 10.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME77375.1 - 0.052 13.5 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME77375.1 - 0.084 11.7 0.0 0.8 8.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EME77375.1 - 0.095 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3886 PF13025.1 EME77376.1 - 0.011 15.7 1.3 0.015 15.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF1253 PF06862.7 EME77376.1 - 0.027 12.9 0.3 0.029 12.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CTNNB1_binding PF08347.6 EME77376.1 - 0.16 12.1 0.9 0.19 11.9 0.6 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding FAT PF02259.18 EME77378.1 - 2.6e-121 404.9 2.5 2.6e-121 404.9 1.7 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EME77378.1 - 9.8e-61 205.2 0.2 1.8e-60 204.3 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EME77378.1 - 1e-53 181.5 2.3 3.6e-50 170.0 0.0 6.0 6 1 1 7 7 7 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EME77378.1 - 3.8e-41 139.2 0.0 3.8e-41 139.2 0.0 3.7 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EME77378.1 - 3.8e-17 62.3 20.5 0.016 15.4 0.0 10.9 6 2 6 12 12 12 7 HEAT repeats FATC PF02260.15 EME77378.1 - 1.8e-15 56.0 0.2 4.4e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EME77378.1 - 6.5e-12 44.4 20.9 1.5 9.1 0.0 11.8 12 0 0 12 12 12 5 HEAT repeat HEAT_EZ PF13513.1 EME77378.1 - 3.7e-09 36.8 11.2 0.11 12.9 0.0 9.8 11 0 0 11 11 9 2 HEAT-like repeat Adaptin_N PF01602.15 EME77378.1 - 3.1e-05 22.5 7.0 0.11 10.7 1.0 6.1 4 2 1 5 5 5 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EME77378.1 - 7.8e-05 22.9 5.6 35 4.8 0.0 7.5 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region ParcG PF10274.4 EME77378.1 - 0.0013 18.6 4.0 0.38 10.6 0.1 4.4 4 0 0 4 4 4 1 Parkin co-regulated protein CLASP_N PF12348.3 EME77378.1 - 0.0093 15.3 6.0 0.8 9.0 0.0 4.9 5 0 0 5 5 5 1 CLASP N terminal TPR_19 PF14559.1 EME77378.1 - 0.011 15.9 0.5 2.5 8.4 0.1 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Fumble PF03630.9 EME77380.1 - 2.7e-130 434.2 0.3 2.7e-129 430.8 0.2 1.9 1 1 0 1 1 1 1 Fumble Rtf2 PF04641.7 EME77381.1 - 2.7e-56 190.6 3.6 3.2e-56 190.4 2.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EME77381.1 - 3.5e-06 26.4 0.0 8.5e-05 22.0 0.0 2.4 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EME77381.1 - 0.0081 15.8 0.4 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 EME77381.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 1 0 0 1 1 1 0 U-box domain zf-RING_5 PF14634.1 EME77381.1 - 0.13 11.9 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain GMC_oxred_N PF00732.14 EME77383.1 - 4.4e-54 183.6 0.0 6.1e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME77383.1 - 1.7e-39 135.3 0.0 2.8e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EME77383.1 - 4.7e-06 25.7 0.0 0.00042 19.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME77383.1 - 2.9e-05 23.1 0.0 0.086 11.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME77383.1 - 4.2e-05 23.4 0.0 0.00014 21.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME77383.1 - 4.3e-05 22.6 0.0 6.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EME77383.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EME77383.1 - 0.035 13.9 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME77383.1 - 0.042 12.9 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME77383.1 - 0.058 13.8 0.1 0.53 10.7 0.0 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME77383.1 - 0.071 11.5 0.0 0.21 10.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Aldedh PF00171.17 EME77384.1 - 5e-154 513.0 0.0 5.9e-154 512.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-piccolo PF05715.8 EME77385.1 - 0.1 12.6 0.4 0.2 11.6 0.3 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Ribosomal_L50 PF10501.4 EME77386.1 - 3.9e-09 36.4 0.5 9.2e-09 35.2 0.4 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S Ribosomal_L6e PF01159.14 EME77386.1 - 0.36 11.0 5.1 0.13 12.4 0.6 2.4 3 0 0 3 3 3 0 Ribosomal protein L6e RICTOR_N PF14664.1 EME77387.1 - 2.1e-121 405.0 1.4 1.8e-120 401.9 0.2 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EME77387.1 - 6.2e-79 264.1 0.6 8.1e-78 260.5 0.2 2.9 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EME77387.1 - 1.9e-42 143.8 0.1 3.8e-41 139.6 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EME77387.1 - 4.6e-28 96.9 0.2 1.7e-25 88.7 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EME77387.1 - 5.2e-09 35.7 10.5 1.4e-08 34.3 7.3 1.7 1 0 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.1 EME77387.1 - 0.022 15.2 0.2 14 6.3 0.2 4.1 3 0 0 3 3 3 0 HEAT-like repeat SspB PF04386.8 EME77387.1 - 0.55 9.8 3.4 1.3 8.5 2.3 1.6 1 0 0 1 1 1 0 Stringent starvation protein B Uricase PF01014.13 EME77388.1 - 9.7e-81 268.6 1.5 2.4e-40 137.8 0.8 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 EME77389.1 - 3.8e-43 146.5 0.1 4.6e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 ATP-synt_C PF00137.16 EME77390.1 - 4e-28 97.1 25.2 3.2e-17 62.1 6.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF3176 PF11374.3 EME77393.1 - 0.00023 20.9 4.5 0.00034 20.4 1.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) MFS_1 PF07690.11 EME77395.1 - 2.4e-22 79.1 28.4 2.6e-22 79.0 19.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S26e PF01283.14 EME77398.1 - 0.066 13.4 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S26e DNA_RNApol_7kD PF03604.8 EME77398.1 - 0.1 12.0 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit OB_NTP_bind PF07717.11 EME77399.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME77400.1 - 3.4e-19 68.7 0.2 6e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME77400.1 - 3.2e-13 49.3 0.1 6.5e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME77400.1 - 1.4e-08 34.3 0.0 2.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EME77400.1 - 0.03 13.2 0.0 0.064 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EME77400.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME77400.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EME77400.1 - 0.065 12.9 0.2 1.2 8.8 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain Pkinase PF00069.20 EME77402.1 - 1.7e-61 207.6 0.0 4.3e-61 206.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77402.1 - 9.3e-28 96.9 0.0 2.4e-27 95.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME77402.1 - 0.00026 20.0 0.0 0.0022 17.0 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME77402.1 - 0.00095 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME77402.1 - 0.21 11.2 6.8 0.98 9.0 4.7 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF4510 PF14971.1 EME77402.1 - 0.31 11.1 6.2 1.1 9.4 4.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) NARP1 PF12569.3 EME77402.1 - 0.46 9.1 6.4 0.62 8.7 4.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PGBA_C PF15437.1 EME77402.1 - 0.56 10.3 20.2 1.7 8.8 14.0 1.8 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal IncA PF04156.9 EME77402.1 - 2.1 7.9 5.9 0.57 9.7 0.1 2.1 2 0 0 2 2 2 0 IncA protein Oxysterol_BP PF01237.13 EME77402.1 - 2.3 6.6 8.5 3.1 6.1 5.9 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein U79_P34 PF03064.11 EME77402.1 - 2.3 7.6 8.0 3.7 6.9 5.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4554 PF15091.1 EME77402.1 - 4.6 5.8 5.2 7.3 5.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Methyltransf_28 PF02636.12 EME77403.1 - 4.2e-76 255.6 0.0 5.3e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Acetyltransf_1 PF00583.19 EME77404.1 - 5.5e-09 35.9 0.0 9.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME77404.1 - 1.6e-07 31.3 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME77404.1 - 7.3e-05 22.6 0.0 0.0002 21.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME77404.1 - 0.0002 21.4 0.1 0.00086 19.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME77404.1 - 0.00073 19.2 0.0 0.0026 17.4 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EME77404.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ILVD_EDD PF00920.16 EME77405.1 - 7.7e-152 506.3 0.0 9e-152 506.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_54 PF04666.8 EME77406.1 - 2.1e-13 49.7 0.0 1.4e-07 30.5 0.0 3.0 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region BCS1_N PF08740.6 EME77407.1 - 1.9e-44 151.5 0.4 2.9e-44 150.9 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EME77407.1 - 6.3e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME77407.1 - 5.5e-05 22.6 0.0 0.00013 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME77407.1 - 7.4e-05 22.4 0.0 0.00023 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME77407.1 - 0.00012 22.8 0.0 0.00049 20.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME77407.1 - 0.00021 21.3 0.1 0.0017 18.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EME77407.1 - 0.00092 18.3 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EME77407.1 - 0.0032 16.4 0.0 0.0067 15.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EME77407.1 - 0.0048 16.4 0.1 0.038 13.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME77407.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME77407.1 - 0.007 16.6 0.0 0.058 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EME77407.1 - 0.0076 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 EME77407.1 - 0.013 15.2 0.1 0.094 12.4 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain AAA_33 PF13671.1 EME77407.1 - 0.015 15.1 0.1 0.049 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME77407.1 - 0.028 14.5 0.0 0.088 12.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EME77407.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EME77407.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EME77407.1 - 0.067 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 EME77407.1 - 0.13 11.8 0.0 0.73 9.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EME77407.1 - 0.23 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ACP_syn_III PF08545.5 EME77408.1 - 0.1 12.2 0.4 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Brix PF04427.13 EME77409.1 - 4.3e-53 179.8 0.3 6e-53 179.3 0.2 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.5 EME77409.1 - 0.042 12.9 38.4 0.079 12.0 2.0 2.6 3 0 0 3 3 3 0 BUD22 HD_4 PF13328.1 EME77409.1 - 0.45 10.2 6.6 0.82 9.3 0.0 3.6 4 0 0 4 4 4 0 HD domain DEAD PF00270.24 EME77410.1 - 3.2e-46 156.9 0.0 5.9e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME77410.1 - 2.1e-25 88.3 0.0 5.5e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME77410.1 - 3.8e-05 23.6 0.0 0.0002 21.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME77410.1 - 0.0023 16.7 0.0 0.01 14.6 0.0 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain 4HBT PF03061.17 EME77411.1 - 3e-13 49.7 0.1 4.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME77411.1 - 0.12 12.0 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF1676 PF07898.8 EME77412.1 - 1.6 9.0 4.9 2.3 8.5 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) MIF4G PF02854.14 EME77413.1 - 5.2e-47 159.9 0.7 9e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EME77413.1 - 1.4e-14 53.7 0.3 4.9e-14 51.9 0.2 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Homeobox PF00046.24 EME77415.1 - 2.1e-17 62.4 3.9 4.3e-17 61.4 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EME77415.1 - 0.00029 20.4 0.1 0.00086 18.9 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain M-inducer_phosp PF06617.8 EME77415.1 - 0.006 15.6 0.3 0.01 14.8 0.2 1.3 1 0 0 1 1 1 1 M-phase inducer phosphatase efThoc1 PF11957.3 EME77417.1 - 1.6e-112 376.5 1.1 2e-99 333.3 0.2 2.0 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor Swi3 PF07962.7 EME77418.1 - 2.2e-29 100.8 0.2 3.7e-29 100.1 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 BTB PF00651.26 EME77419.1 - 2.8e-06 27.2 0.0 6.1e-06 26.1 0.0 1.6 1 1 1 2 2 2 1 BTB/POZ domain Peptidase_C31 PF05410.8 EME77419.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha BTB PF00651.26 EME77420.1 - 8.5e-05 22.5 0.0 9.5e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 BTB/POZ domain ECH PF00378.15 EME77422.1 - 1.2e-68 230.9 0.0 1.4e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EME77422.1 - 0.023 14.8 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 EME77423.1 - 7.7e-78 260.1 5.4 8.6e-78 259.9 3.8 1.0 1 0 0 1 1 1 1 Rer1 family DUF962 PF06127.6 EME77423.1 - 0.28 11.0 3.3 4.1 7.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF3419 PF11899.3 EME77424.1 - 1.8e-142 474.5 0.0 2.9e-142 473.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EME77424.1 - 2.1e-09 37.2 0.0 9.7e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME77424.1 - 7.5e-09 35.9 0.0 5.4e-08 33.2 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME77424.1 - 2.5e-07 31.0 0.0 8.5e-05 22.9 0.0 4.2 4 1 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77424.1 - 3e-06 26.9 0.0 9.7e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME77424.1 - 4e-06 27.3 0.0 3e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME77424.1 - 4.1e-06 26.8 0.0 0.00012 22.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME77424.1 - 0.00075 18.6 0.1 0.091 11.8 0.0 2.6 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EME77424.1 - 0.0091 15.5 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EME77424.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase HSF_DNA-bind PF00447.12 EME77425.1 - 7e-36 122.5 0.6 1.2e-35 121.7 0.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.17 EME77425.1 - 0.12 12.5 0.2 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Ets-domain Med13_C PF06333.7 EME77425.1 - 5.1 5.5 7.2 13 4.1 5.0 1.8 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal Peptidase_S8 PF00082.17 EME77426.1 - 9.2e-06 25.0 0.8 1.2e-05 24.6 0.5 1.1 1 0 0 1 1 1 1 Subtilase family Cyto_heme_lyase PF01265.12 EME77427.1 - 3.3e-76 256.3 1.2 3.8e-76 256.1 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase RRM_1 PF00076.17 EME77428.1 - 1.2e-09 37.6 0.0 2.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME77428.1 - 2.7e-09 36.8 0.0 4.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME77428.1 - 5.4e-06 26.0 0.0 8.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EME77428.1 - 0.021 14.6 0.0 0.062 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA binding motif F-box-like_2 PF13013.1 EME77429.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 F-box-like domain DnaJ PF00226.26 EME77430.1 - 7.3e-14 51.2 2.7 2e-13 49.8 0.0 2.7 3 0 0 3 3 3 1 DnaJ domain F-box PF00646.28 EME77431.1 - 0.033 13.8 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 F-box domain Rsbr_N PF08678.5 EME77431.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Rsbr N terminal CheB_methylest PF01339.12 EME77434.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 CheB methylesterase Glyco_hydro_65m PF03632.10 EME77435.1 - 9.9e-75 251.5 0.0 1.3e-73 247.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EME77435.1 - 7.4e-36 123.7 0.0 1.9e-35 122.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EME77435.1 - 3.4e-06 27.0 0.1 8.4e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.20 EME77435.1 - 0.00064 19.5 0.5 0.0028 17.5 0.1 2.3 2 0 0 2 2 2 1 F5/8 type C domain PTR2 PF00854.16 EME77436.1 - 3.4e-47 161.0 20.3 5.2e-47 160.4 11.5 2.7 1 1 1 2 2 2 2 POT family DUF3431 PF11913.3 EME77438.1 - 6.8e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) IGR PF09597.5 EME77438.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 IGR protein motif GDC-P PF02347.11 EME77440.1 - 2e-178 593.5 0.0 2.4e-164 547.0 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EME77440.1 - 6.2e-06 25.5 1.4 2.6e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EME77440.1 - 0.0087 15.0 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II F-box-like PF12937.2 EME77441.1 - 1.8e-06 27.5 0.2 2.6e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME77441.1 - 7.6e-06 25.4 0.1 1.6e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF3210 PF11489.3 EME77442.1 - 7.3e-139 464.6 89.2 6.1e-120 402.0 41.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3210) Actin PF00022.14 EME77443.1 - 4.5e-29 101.0 0.0 4.7e-17 61.4 0.0 2.3 2 1 0 2 2 2 2 Actin DUF2114 PF09887.4 EME77443.1 - 0.013 13.8 0.4 0.018 13.3 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) NTF2 PF02136.15 EME77444.1 - 7.2e-31 107.0 0.1 8.1e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EME77444.1 - 0.063 12.3 0.2 0.072 12.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Cg6151-P PF10233.4 EME77445.1 - 1.3e-41 141.0 16.4 1.6e-41 140.8 11.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2207 PF09972.4 EME77445.1 - 0.0073 14.9 6.1 0.0089 14.6 4.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PRA1 PF03208.14 EME77445.1 - 0.022 14.1 1.7 0.022 14.1 1.2 2.2 1 1 2 3 3 3 0 PRA1 family protein Cytochrom_B_N PF00033.14 EME77445.1 - 0.025 13.9 3.7 0.16 11.3 2.5 2.1 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PEMT PF04191.8 EME77445.1 - 0.051 13.6 2.1 0.051 13.6 1.4 2.3 2 1 0 2 2 2 0 Phospholipid methyltransferase Ni_hydr_CYTB PF01292.15 EME77445.1 - 0.36 10.1 4.4 0.17 11.2 1.1 1.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Cytochrom_B558a PF05038.8 EME77445.1 - 1.5 8.4 7.1 0.18 11.4 0.2 2.3 2 1 1 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit NfeD PF01957.13 EME77445.1 - 1.6 8.8 8.0 1.4 9.0 0.4 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding TraP PF07296.6 EME77445.1 - 2.5 7.0 5.1 0.33 9.8 0.5 1.7 2 0 0 2 2 2 0 TraP protein DUF2721 PF11026.3 EME77445.1 - 2.7 7.6 13.9 1.5 8.4 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) YwiC PF14256.1 EME77445.1 - 3.9 7.5 11.7 10 6.2 8.1 1.7 1 1 0 1 1 1 0 YwiC-like protein TMEM220 PF15071.1 EME77445.1 - 9 6.7 9.1 18 5.8 0.8 2.1 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF3125 PF11323.3 EME77446.1 - 0.01 15.5 0.3 0.024 14.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3125) Oxidored-like PF09791.4 EME77449.1 - 6.8e-24 83.0 1.7 1.5e-23 81.9 1.2 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal FAD_binding_4 PF01565.18 EME77450.1 - 5e-11 42.2 0.0 7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME77451.1 - 0.0011 18.8 1.9 0.0027 17.5 1.0 2.0 2 1 0 2 2 2 1 Berberine and berberine like TAFII28 PF04719.9 EME77454.1 - 0.011 15.5 0.3 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region MCR_gamma PF02240.11 EME77454.1 - 0.049 12.7 0.2 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit TPT PF03151.11 EME77455.1 - 3.5e-27 94.9 12.1 3.5e-27 94.9 8.4 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EME77455.1 - 1.7e-05 23.9 20.4 0.00052 19.0 14.1 2.3 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 EME77455.1 - 0.012 14.4 16.3 0.011 14.5 10.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) HAD_2 PF13419.1 EME77456.1 - 3.7e-19 69.6 0.0 4.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME77456.1 - 0.0018 17.9 0.1 0.053 13.2 0.0 2.7 3 0 0 3 3 3 1 HAD-hyrolase-like DUF1793 PF08760.6 EME77457.1 - 6e-27 94.5 0.4 1.2e-26 93.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) VirE3 PF06661.6 EME77458.1 - 0.059 12.4 1.2 3 6.8 0.1 2.1 1 1 1 2 2 2 0 VirE3 NOPS PF08075.6 EME77458.1 - 0.23 11.8 1.4 1.2e+02 3.2 0.0 3.2 1 1 2 3 3 3 0 NOPS (NUC059) domain Gag_p12 PF01141.13 EME77459.1 - 0.15 12.2 2.2 5.1 7.2 0.2 2.3 1 1 1 2 2 2 0 Gag polyprotein, inner coat protein p12 DUF3328 PF11807.3 EME77460.1 - 1.2e-35 123.1 1.0 1.5e-35 122.8 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EME77461.1 - 4.6e-31 108.1 0.1 5.4e-31 107.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) VQ PF05678.9 EME77461.1 - 0.078 12.0 1.1 0.17 10.9 0.1 2.0 2 0 0 2 2 2 0 VQ motif DUF3328 PF11807.3 EME77462.1 - 5e-29 101.5 0.2 5.5e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NADH-u_ox-rdase PF10785.4 EME77464.1 - 1.7e-32 111.4 0.4 3.3e-32 110.5 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EME77464.1 - 9e-32 108.6 0.1 1.4e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit AAA_12 PF13087.1 EME77465.1 - 2.9e-28 98.6 0.0 5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME77465.1 - 7.8e-24 84.5 0.0 1.5e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME77465.1 - 9e-10 38.1 0.2 3.2e-09 36.4 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EME77465.1 - 4.2e-06 26.4 0.0 0.00068 19.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EME77465.1 - 3.2e-05 23.8 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EME77465.1 - 0.00055 20.1 0.1 0.0047 17.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME77465.1 - 0.0006 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME77465.1 - 0.0028 17.6 0.3 0.0028 17.6 0.2 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EME77465.1 - 0.0032 17.5 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain DEAD PF00270.24 EME77465.1 - 0.0093 15.4 0.2 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EME77465.1 - 0.0097 16.0 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 EME77465.1 - 0.023 13.6 1.4 0.024 13.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EME77465.1 - 0.024 13.7 0.2 0.062 12.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 EME77465.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 EME77465.1 - 0.044 13.0 0.6 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_17 PF13207.1 EME77465.1 - 0.066 14.0 0.0 2.3 9.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 EME77465.1 - 0.068 12.3 0.1 0.39 9.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.13 EME77465.1 - 0.071 12.6 0.1 19 4.6 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EME77465.1 - 0.21 10.4 0.0 7.4 5.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.12 EME77465.1 - 0.22 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EME77465.1 - 0.3 11.2 0.0 0.69 10.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RNase_H PF00075.19 EME77467.1 - 3.1e-15 56.6 0.0 4.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EME77467.1 - 1.2e-05 24.9 0.2 0.0069 16.1 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase-like ATP-synt_A PF00119.15 EME77468.1 - 2.5e-11 43.4 27.8 2.7e-11 43.3 19.3 1.0 1 0 0 1 1 1 1 ATP synthase A chain Cytochrom_B_C PF00032.12 EME77469.1 - 2.3e-17 63.0 5.9 2.5e-17 62.9 4.1 1.0 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD ADH_zinc_N PF00107.21 EME77479.1 - 0.033 13.7 0.0 0.091 12.3 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF1633 PF07794.6 EME77482.1 - 0.015 13.2 5.3 0.022 12.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Pex14_N PF04695.8 EME77483.1 - 1.3 9.0 10.3 0.03 14.3 1.3 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M57 PF12388.3 EME77486.1 - 0.065 12.5 0.1 0.065 12.5 0.1 1.0 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase PNPOx_C PF10590.4 EME77487.1 - 0.048 13.1 0.3 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region OprF PF05736.6 EME77488.1 - 0.098 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 OprF membrane domain CENP-F_leu_zip PF10473.4 EME77497.1 - 0.56 10.0 29.8 15 5.4 10.0 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 EME77497.1 - 1.9 8.8 25.3 1.3 9.3 7.4 3.3 1 1 1 2 2 2 0 Striatin family DUF3584 PF12128.3 EME77497.1 - 2.2 5.4 24.8 3.1 5.0 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.1 EME77497.1 - 5.8 5.7 20.7 5.8 5.7 13.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.13 EME77497.1 - 6.1 5.7 8.9 1.1 8.1 3.0 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein RNA_pol_Rpb2_45 PF10385.4 EME77498.1 - 0.079 12.7 0.1 0.58 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain DUF848 PF05852.6 EME77499.1 - 0.05 13.4 0.9 0.1 12.4 0.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) YlaC PF10777.4 EME77501.1 - 0.12 11.9 0.1 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Inner membrane protein YlaC Lysis_S PF04971.7 EME77502.1 - 0.13 11.9 0.4 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Lysis protein S Cwf_Cwc_15 PF04889.7 EME77503.1 - 0.15 11.7 9.9 0.16 11.6 6.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LIN37 PF15306.1 EME77503.1 - 0.18 11.7 4.2 0.25 11.3 2.9 1.2 1 0 0 1 1 1 0 LIN37 FlxA PF14282.1 EME77503.1 - 5.9 6.8 18.0 11 6.0 12.5 1.6 1 1 0 1 1 1 0 FlxA-like protein RNA_pol PF00940.14 EME77504.1 - 2.7e-13 49.1 0.1 2.9e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Stb3 PF10330.4 EME77506.1 - 0.024 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative Sin3 binding protein NYAP_C PF15452.1 EME77507.1 - 0.06 12.3 2.1 0.1 11.6 1.4 1.5 1 1 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter MoCF_biosynth PF00994.19 EME77508.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain DUF605 PF04652.11 EME77508.1 - 5.6 6.2 16.5 0.34 10.2 8.0 1.4 2 0 0 2 2 2 0 Vta1 like DUF447 PF04289.7 EME77510.1 - 0.01 15.4 0.0 0.22 11.0 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF447) Chromo PF00385.19 EME77512.1 - 0.0016 18.0 0.5 0.0064 16.1 0.3 2.0 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RR_TM4-6 PF06459.7 EME77512.1 - 5.7 6.7 13.1 12 5.6 9.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Toxin_3 PF00537.13 EME77514.1 - 0.12 12.3 0.4 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain DNA_pack_C PF02499.10 EME77520.1 - 0.31 9.7 0.0 0.48 9.1 0.0 1.2 1 0 0 1 1 1 0 Probable DNA packing protein, C-terminus Gag_p6 PF08705.6 EME77521.1 - 0.043 13.8 7.2 0.48 10.4 0.1 3.9 4 0 0 4 4 4 0 Gag protein p6 DEAD PF00270.24 EME77523.1 - 0.2 11.1 5.4 5.7 6.4 1.1 3.0 1 1 0 2 2 2 0 DEAD/DEAH box helicase TRAP-gamma PF07074.7 EME77527.1 - 0.46 9.9 4.3 1.9 8.0 0.7 2.9 1 1 1 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DDE_Tnp_4 PF13359.1 EME77529.1 - 1.4e-08 34.5 0.0 1.5e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2838 PF10998.3 EME77529.1 - 0.033 14.0 1.3 0.035 13.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) DDE_Tnp_1 PF01609.16 EME77529.1 - 0.14 11.7 0.4 0.18 11.3 0.3 1.3 1 1 0 1 1 1 0 Transposase DDE domain DUF3328 PF11807.3 EME77531.1 - 5.5e-31 107.9 2.6 7.4e-31 107.5 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4543 PF15076.1 EME77532.1 - 0.016 15.2 10.7 2.8 8.0 0.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4543) DUF4215 PF13948.1 EME77532.1 - 0.09 13.0 13.4 5.5 7.2 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) Toxin_2 PF00451.14 EME77532.1 - 0.49 10.5 11.4 13 5.9 0.3 3.1 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 Toxin_3 PF00537.13 EME77532.1 - 3.1 7.7 13.5 13 5.7 0.3 3.1 2 1 1 3 3 3 0 Scorpion toxin-like domain p450 PF00067.17 EME77534.1 - 1.6e-55 188.4 0.0 2e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 EME77535.1 - 2.6e-28 98.5 0.1 4.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME77535.1 - 9e-20 70.6 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EME77535.1 - 0.052 13.5 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AMP-binding PF00501.23 EME77536.1 - 2.4e-163 543.3 0.0 7.9e-86 288.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EME77536.1 - 2.3e-81 272.9 0.1 3.1e-50 170.7 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EME77536.1 - 1.7e-24 85.8 0.2 8.9e-12 45.1 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EME77536.1 - 1.3e-18 67.0 0.0 4e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EME77536.1 - 2.5e-11 44.3 0.1 0.0025 18.7 0.0 4.6 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.7 EME77536.1 - 0.00053 20.4 0.0 0.0026 18.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME77536.1 - 0.00055 19.6 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77536.1 - 0.00057 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME77536.1 - 0.00078 19.7 0.0 0.0037 17.5 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME77536.1 - 0.0024 17.9 0.0 0.026 14.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME77536.1 - 0.009 16.5 0.0 0.034 14.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EME77537.1 - 3.7e-17 62.7 0.1 6.5e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME77537.1 - 4.2e-06 26.5 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME77537.1 - 1.3e-05 25.1 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME77537.1 - 0.00077 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME77537.1 - 0.035 14.1 0.0 0.072 13.0 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding ketoacyl-synt PF00109.21 EME77538.1 - 2.3e-68 230.4 0.0 4.7e-68 229.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EME77538.1 - 1.6e-54 185.3 0.2 3.8e-54 184.1 0.1 1.6 1 1 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EME77538.1 - 2.5e-54 183.7 3.5 3e-54 183.4 1.6 1.8 2 0 0 2 2 1 1 KR domain PS-DH PF14765.1 EME77538.1 - 1.7e-50 171.9 1.3 2.9e-50 171.0 0.9 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EME77538.1 - 4.8e-45 153.4 2.1 1.2e-44 152.1 1.4 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EME77538.1 - 1.9e-34 118.0 0.1 6.1e-34 116.4 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EME77538.1 - 2.7e-19 69.4 0.0 3.2e-18 66.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77538.1 - 5.6e-12 45.5 0.0 1.4e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME77538.1 - 9.8e-12 45.2 0.0 8.2e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME77538.1 - 3.7e-08 33.2 0.0 5.5e-07 29.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME77538.1 - 5.9e-08 33.2 0.1 1.1e-06 29.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME77538.1 - 1.2e-07 31.1 0.0 2.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EME77538.1 - 2.1e-06 27.8 0.0 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EME77538.1 - 0.00095 17.9 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_26 PF13659.1 EME77538.1 - 0.0015 18.5 0.0 0.0089 16.0 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EME77538.1 - 0.0016 17.4 0.1 0.0035 16.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EME77538.1 - 0.026 14.1 0.4 0.082 12.5 0.3 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF915 PF06028.6 EME77538.1 - 1.6 7.7 0.0 4.1 6.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Pyr_redox_3 PF13738.1 EME77539.1 - 3.5e-24 85.9 0.0 5e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME77539.1 - 9.2e-11 41.2 0.0 3.8e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EME77539.1 - 9.3e-11 40.6 0.0 2.1e-07 29.5 0.0 2.8 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME77539.1 - 5.4e-09 36.2 0.0 1.5e-07 31.4 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME77539.1 - 1.8e-07 31.0 2.1 0.001 18.8 0.3 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME77539.1 - 2.1e-07 30.8 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME77539.1 - 6.7e-07 28.5 0.6 0.029 13.2 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EME77539.1 - 3.5e-05 22.4 0.9 0.11 10.9 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.7 EME77539.1 - 0.011 14.6 1.1 0.086 11.7 0.2 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EME77539.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EME77539.1 - 0.043 12.6 0.2 9.1 5.0 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Potass_KdpF PF09604.5 EME77539.1 - 0.27 11.0 3.3 0.75 9.6 2.3 1.8 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) p450 PF00067.17 EME77540.1 - 3e-30 105.1 0.0 4.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HAD PF12710.2 EME77541.1 - 3.2e-08 33.9 0.0 4.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase VCBS PF13517.1 EME77541.1 - 0.14 12.5 1.5 0.43 10.9 0.1 2.5 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PP28 PF10252.4 EME77543.1 - 9.7e-29 99.2 23.2 9.7e-29 99.2 16.1 3.3 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Anophelin PF10731.4 EME77543.1 - 0.047 13.8 0.9 0.047 13.8 0.6 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Spore_YhaL PF14147.1 EME77543.1 - 0.55 9.7 4.8 2.3 7.7 3.4 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL BTB PF00651.26 EME77545.1 - 9.6e-08 32.0 0.0 5.9e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EME77546.1 - 2.8e-08 33.7 0.0 2e-07 30.9 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain DUF1664 PF07889.7 EME77547.1 - 0.044 13.5 0.2 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PigN PF04987.9 EME77547.1 - 0.051 12.2 0.2 0.068 11.8 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Sulfotransfer_3 PF13469.1 EME77548.1 - 0.017 16.0 0.1 0.071 14.0 0.1 1.9 1 1 0 1 1 1 0 Sulfotransferase family Abhydrolase_2 PF02230.11 EME77551.1 - 2.7e-36 125.0 0.0 3.5e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EME77551.1 - 1.4e-08 34.6 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME77551.1 - 8.1e-08 32.4 0.0 0.00019 21.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EME77551.1 - 0.0097 15.3 0.0 0.024 14.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EME77551.1 - 0.021 14.5 0.0 0.075 12.7 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cutinase PF01083.17 EME77551.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cutinase zf-HIT PF04438.11 EME77552.1 - 1.1e-09 37.7 6.2 1.7e-09 37.1 4.3 1.3 1 0 0 1 1 1 1 HIT zinc finger IFT43 PF15305.1 EME77552.1 - 0.046 13.7 6.2 0.051 13.6 0.1 2.3 2 1 0 2 2 2 0 Intraflagellar transport protein 43 SAGA-Tad1 PF12767.2 EME77552.1 - 0.16 11.6 2.8 0.26 10.9 2.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PGA2 PF07543.7 EME77552.1 - 4.9 6.9 9.3 1.2 8.9 3.4 2.0 1 1 1 2 2 2 0 Protein trafficking PGA2 Y_phosphatase PF00102.22 EME77555.1 - 1.7e-50 171.5 0.0 2.7e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EME77555.1 - 0.0043 16.6 0.1 0.0097 15.4 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain IFRD_C PF04836.7 EME77555.1 - 0.016 15.3 0.1 0.016 15.3 0.0 2.6 3 0 0 3 3 3 0 Interferon-related protein conserved region PTPlike_phytase PF14566.1 EME77555.1 - 0.018 15.0 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EME77555.1 - 0.036 14.3 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2697 PF10906.3 EME77556.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2697) MFS_1 PF07690.11 EME77557.1 - 1.5e-33 116.0 15.1 2.2e-33 115.4 10.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LigB PF02900.13 EME77558.1 - 1.2e-12 47.3 0.0 2.6e-08 33.1 0.0 2.0 1 1 1 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Cupin_1 PF00190.17 EME77559.1 - 5.8e-31 106.8 0.0 1.8e-15 56.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EME77559.1 - 2.5e-25 87.7 0.8 5e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EME77559.1 - 1.8e-11 43.2 0.0 2.3e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EME77559.1 - 9.7e-08 31.7 0.2 0.00032 20.3 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain FdtA PF05523.6 EME77559.1 - 0.0005 19.5 0.0 0.68 9.4 0.0 2.5 2 1 0 2 2 2 2 WxcM-like, C-terminal Cupin_6 PF12852.2 EME77559.1 - 0.0026 17.3 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 2 Cupin ARD PF03079.9 EME77559.1 - 0.012 15.6 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family MannoseP_isomer PF01050.13 EME77559.1 - 0.015 14.9 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase CENP-C_C PF11699.3 EME77559.1 - 0.033 14.1 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Mif2/CENP-C like DUF1275 PF06912.6 EME77560.1 - 1.7e-33 115.6 14.5 2.3e-33 115.1 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2207 PF09972.4 EME77560.1 - 4.4 5.7 5.3 0.9 8.0 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF829 PF05705.9 EME77561.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) DUF2013 PF09431.5 EME77562.1 - 8.7e-45 151.9 0.2 2.9e-44 150.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) UCH PF00443.24 EME77564.1 - 1.6e-38 132.3 0.0 2.7e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EME77564.1 - 6.9e-20 70.2 0.2 2.7e-10 39.4 0.1 4.0 4 0 0 4 4 4 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EME77564.1 - 1e-13 51.4 0.0 4.1e-12 46.1 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase F-box-like PF12937.2 EME77565.1 - 0.0012 18.5 1.7 0.0033 17.0 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME77565.1 - 0.0099 15.5 0.1 0.0099 15.5 0.1 3.4 3 1 1 4 4 4 1 F-box domain RINT1_TIP1 PF04437.8 EME77566.1 - 8e-131 436.9 0.6 1.5e-130 436.0 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family GldM_N PF12081.3 EME77566.1 - 0.12 11.8 4.7 0.26 10.7 3.3 1.5 1 0 0 1 1 1 0 GldM N-terminal domain Bul1_C PF04426.7 EME77566.1 - 0.54 9.3 3.6 0.99 8.5 2.5 1.4 1 0 0 1 1 1 0 Bul1 C terminus V_ATPase_I PF01496.14 EME77566.1 - 6.2 4.5 6.4 11 3.7 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipoprotein_6 PF01441.14 EME77566.1 - 6.3 6.5 9.5 5.4 6.8 5.4 1.7 2 0 0 2 2 2 0 Lipoprotein RdRP PF05183.7 EME77568.1 - 8.1e-157 523.3 0.0 2.2e-156 521.9 0.0 1.7 2 0 0 2 2 2 1 RNA dependent RNA polymerase HHH PF00633.18 EME77575.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Halo_GVPC PF05465.8 EME77575.1 - 0.42 10.5 2.6 0.82 9.6 1.8 1.5 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat MFS_1 PF07690.11 EME77576.1 - 1e-32 113.2 31.6 2.9e-32 111.7 21.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DENN PF02141.16 EME77577.1 - 0.075 12.7 0.7 0.13 11.9 0.3 1.5 2 0 0 2 2 2 0 DENN (AEX-3) domain DUF1013 PF06242.6 EME77577.1 - 0.12 12.3 1.5 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) FAD_binding_3 PF01494.14 EME77578.1 - 2.9e-08 33.1 0.9 5.5e-08 32.2 0.1 1.8 2 1 0 2 2 2 1 FAD binding domain SE PF08491.5 EME77578.1 - 0.0064 15.3 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Amino_oxidase PF01593.19 EME77578.1 - 0.038 13.0 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF3885 PF13021.1 EME77578.1 - 0.096 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) NAD_binding_9 PF13454.1 EME77578.1 - 0.11 12.2 0.0 14 5.3 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding p450 PF00067.17 EME77579.1 - 1.7e-38 132.3 0.1 1.9e-37 128.9 0.1 2.2 1 1 0 1 1 1 1 Cytochrome P450 Holin_LLH PF09682.5 EME77579.1 - 0.13 12.3 0.6 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Phage holin protein (Holin_LLH) DUF3552 PF12072.3 EME77582.1 - 0.018 14.2 2.5 0.032 13.4 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4337 PF14235.1 EME77582.1 - 0.38 10.5 2.3 0.89 9.3 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BTB PF00651.26 EME77583.1 - 1.9e-05 24.5 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ph1570 PF09638.5 EME77583.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Ph1570 protein Glyco_hydro_47 PF01532.15 EME77585.1 - 5.1e-170 565.9 0.2 5.8e-170 565.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 BTB PF00651.26 EME77586.1 - 0.15 12.0 0.0 0.57 10.1 0.0 1.9 3 0 0 3 3 3 0 BTB/POZ domain MFS_1 PF07690.11 EME77588.1 - 3.3e-36 124.7 32.8 5e-36 124.1 22.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily YesK PF14150.1 EME77588.1 - 0.021 14.9 0.8 0.021 14.9 0.6 3.4 3 1 1 4 4 4 0 YesK-like protein GMC_oxred_N PF00732.14 EME77589.1 - 6.6e-58 196.1 0.0 9.2e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME77589.1 - 7.8e-30 104.0 0.0 1.2e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 EME77589.1 - 0.00047 20.2 0.0 0.038 14.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME77589.1 - 0.0018 17.2 0.2 0.0047 15.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EME77589.1 - 0.0037 16.2 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EME77589.1 - 0.0041 16.0 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME77589.1 - 0.021 14.8 0.1 0.09 12.8 0.0 2.0 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME77589.1 - 0.043 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME77589.1 - 0.068 13.1 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EME77589.1 - 0.13 10.7 0.5 0.46 8.8 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_4 PF01565.18 EME77594.1 - 2.9e-28 98.0 5.8 6.4e-28 96.9 4.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME77594.1 - 4.2e-07 29.7 0.2 1.3e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like His_Phos_1 PF00300.17 EME77595.1 - 4.9e-18 65.7 0.0 6.4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HrpB_C PF08482.5 EME77595.1 - 0.067 13.3 0.1 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal AA_permease_2 PF13520.1 EME77596.1 - 9.2e-42 143.0 50.7 1.2e-41 142.6 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME77596.1 - 2.9e-23 81.9 45.7 3.6e-23 81.6 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease BTB PF00651.26 EME77597.1 - 0.0012 18.7 0.1 0.013 15.5 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain DUF1680 PF07944.7 EME77599.1 - 0.0085 14.4 0.0 0.01 14.1 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) SMP PF04927.7 EME77600.1 - 0.0049 16.8 5.0 0.0089 15.9 3.5 1.5 1 1 0 1 1 1 1 Seed maturation protein WSC PF01822.14 EME77603.1 - 5.4e-13 48.6 14.2 5.4e-13 48.6 9.8 2.2 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EME77603.1 - 2.1e-07 30.1 1.8 2.1e-07 30.1 1.3 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Protocadherin PF08374.6 EME77603.1 - 0.016 14.8 0.1 0.016 14.8 0.0 2.2 2 1 1 3 3 3 0 Protocadherin DUF2567 PF10821.3 EME77603.1 - 0.022 14.2 1.4 0.033 13.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) DUF4448 PF14610.1 EME77603.1 - 0.044 13.2 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.2 EME77603.1 - 0.056 12.6 0.1 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 EME77603.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.6 EME77603.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 DAP10 membrane protein DUF4402 PF14352.1 EME77603.1 - 0.35 11.3 13.5 0.59 10.6 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Mid2 PF04478.7 EME77603.1 - 1.5 8.2 7.0 0.89 8.9 3.6 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor CD99L2 PF12301.3 EME77603.1 - 1.5 8.4 6.7 25 4.5 4.6 2.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 FSH1 PF03959.8 EME77606.1 - 6.2e-30 104.2 0.0 8.2e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EME77606.1 - 0.00099 19.0 0.2 0.0025 17.7 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME77606.1 - 0.004 16.9 0.0 0.0074 16.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME77606.1 - 0.069 12.5 0.0 3.7 6.9 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EME77607.1 - 1.9e-10 41.0 0.0 2.1e-09 37.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME77607.1 - 2.2e-09 37.1 0.0 7.8e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME77607.1 - 2.2e-05 24.1 0.1 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME77607.1 - 0.02 14.1 0.0 0.065 12.4 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EME77607.1 - 0.035 13.5 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EME77607.1 - 0.061 13.1 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Kelch_3 PF13415.1 EME77608.1 - 1.5e-32 110.9 12.9 4.9e-10 39.2 0.0 8.3 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EME77608.1 - 4.6e-30 103.1 10.6 1e-08 34.7 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 EME77608.1 - 2.7e-24 84.8 0.9 2.7e-24 84.8 0.6 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 EME77608.1 - 2.8e-22 77.8 4.1 5.6e-06 26.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EME77608.1 - 8.2e-20 70.3 5.8 0.00031 20.6 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EME77608.1 - 2e-16 58.9 5.3 0.0045 16.6 0.0 6.4 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EME77608.1 - 3.5e-13 48.8 2.3 1.2e-06 27.9 0.0 6.0 5 1 0 5 5 5 2 Kelch motif ISG65-75 PF11727.3 EME77608.1 - 6.1 5.8 15.5 2.3 7.1 6.2 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein WLM PF08325.5 EME77609.1 - 1.3e-46 158.8 1.4 1.9e-46 158.2 0.1 1.9 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 EME77609.1 - 6.8e-07 29.2 1.6 1.9e-06 27.8 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 EME77609.1 - 0.015 14.3 4.1 0.015 14.3 2.8 2.4 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C3HC4_2 PF13923.1 EME77609.1 - 0.63 10.1 10.1 1.7 8.7 7.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EME77609.1 - 1.1 8.3 7.2 0.091 11.9 0.9 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger SDA1 PF05285.7 EME77609.1 - 3.3 6.9 15.9 0.017 14.4 5.1 1.5 2 0 0 2 2 2 0 SDA1 SnoaL PF07366.7 EME77610.1 - 3.2e-05 23.4 0.0 7.1e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EME77610.1 - 0.0082 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain 2-oxoacid_dh PF00198.18 EME77611.1 - 1.5e-79 266.4 0.2 2.1e-79 266.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME77611.1 - 1e-15 57.1 1.8 2.4e-15 55.9 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EME77611.1 - 0.0013 18.3 0.4 0.29 10.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 EME77611.1 - 0.011 15.4 0.2 0.032 13.8 0.2 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein MIP-T3 PF10243.4 EME77611.1 - 0.13 10.7 27.3 0.17 10.3 18.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.1 EME77611.1 - 0.25 9.8 10.6 0.34 9.4 7.3 1.1 1 0 0 1 1 1 0 Raftlin TP53IP5 PF15331.1 EME77611.1 - 5.4 6.8 12.1 8.8 6.1 8.4 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Hamartin PF04388.7 EME77611.1 - 9.6 4.7 14.0 53 2.2 9.7 1.8 1 1 0 1 1 1 0 Hamartin protein Complex1_LYR PF05347.10 EME77612.1 - 1.4e-10 40.8 0.8 1.9e-10 40.3 0.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME77612.1 - 1.7e-08 34.5 0.5 2.4e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Aminotran_3 PF00202.16 EME77613.1 - 3.1e-44 151.2 0.0 1.5e-23 83.2 0.0 2.8 3 0 0 3 3 3 2 Aminotransferase class-III AAA_26 PF13500.1 EME77613.1 - 5.3e-34 117.5 0.0 2.8e-33 115.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_31 PF13614.1 EME77613.1 - 0.037 13.9 0.2 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME77613.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Aminotran_1_2 PF00155.16 EME77614.1 - 4.8e-41 140.9 0.0 6.2e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EME77614.1 - 0.00036 19.4 0.0 0.0006 18.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 EME77614.1 - 0.019 13.2 0.0 0.026 12.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Histone PF00125.19 EME77615.1 - 9e-26 89.8 0.0 1.1e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME77615.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME77616.1 - 1.7e-22 79.3 0.2 2.3e-22 78.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME77616.1 - 2.2e-05 24.4 1.0 5.5e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EME77616.1 - 0.00029 21.0 0.0 0.00048 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EME77616.1 - 0.016 15.7 0.2 0.022 15.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EME77616.1 - 0.023 14.1 0.1 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain Dicty_REP PF05086.7 EME77617.1 - 2.6 5.6 4.6 3.5 5.2 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein R3H PF01424.17 EME77618.1 - 6.6e-12 44.9 0.0 9e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EME77618.1 - 6.7e-11 41.8 6.9 1.1e-10 41.0 4.8 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EME77618.1 - 5.1e-06 26.2 4.0 7e-06 25.8 2.3 1.5 1 1 0 1 1 1 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 EME77619.1 - 2.7e-96 321.9 0.0 3.4e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 OB_NTP_bind PF07717.11 EME77620.1 - 3.9e-16 58.9 0.1 9e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME77620.1 - 1.6e-14 53.7 0.0 3.8e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME77620.1 - 1.9e-13 50.0 0.0 1e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME77620.1 - 4.8e-08 32.6 0.0 1.7e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME77620.1 - 1e-05 25.7 0.0 8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME77620.1 - 0.0018 17.1 0.0 0.0043 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EME77620.1 - 0.0027 18.0 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 EME77620.1 - 0.0039 16.6 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EME77620.1 - 0.02 14.6 0.0 0.081 12.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EME77620.1 - 0.042 13.7 0.0 2.1 8.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EME77620.1 - 0.043 12.9 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 EFG_II PF14492.1 EME77620.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II KaiC PF06745.8 EME77620.1 - 0.13 11.3 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 KaiC G-alpha PF00503.15 EME77620.1 - 0.17 10.5 2.1 0.14 10.7 0.3 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Exo_endo_phos PF03372.18 EME77621.1 - 5.7e-24 85.4 0.5 1.2e-23 84.3 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EME77621.1 - 3.6e-15 55.1 0.2 2.6e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME77621.1 - 1e-09 38.0 0.1 4.4e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EME77621.1 - 2.6e-06 26.7 1.3 0.13 12.4 0.1 4.0 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EME77621.1 - 8.1e-05 22.2 2.8 0.26 11.6 0.3 3.8 3 0 0 3 3 3 1 Leucine rich repeat Phage_fiber PF03335.8 EME77621.1 - 0.0043 16.4 1.0 0.014 14.9 0.7 2.0 1 0 0 1 1 1 1 Phage tail fibre repeat LRR_6 PF13516.1 EME77621.1 - 0.04 13.9 4.8 2.7 8.3 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat Methyltransf_11 PF08241.7 EME77622.1 - 1.4e-11 44.6 0.0 4.7e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME77622.1 - 4.5e-11 43.0 0.0 8.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME77622.1 - 1.9e-09 38.0 0.0 3.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME77622.1 - 1.5e-08 34.5 0.0 3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME77622.1 - 1.6e-08 34.6 0.0 4.9e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77622.1 - 6e-06 25.9 0.0 9.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME77622.1 - 8.1e-05 21.8 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME77622.1 - 9.1e-05 22.8 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME77622.1 - 0.0037 16.6 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EME77622.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EME77622.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.1 EME77623.1 - 1.5e-06 28.5 0.0 1.8e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME77623.1 - 0.00058 19.6 0.0 0.00076 19.2 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME77623.1 - 0.0024 18.0 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.1 EME77624.1 - 3.2e-22 79.2 0.1 5.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EME77624.1 - 0.0047 17.0 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily ASF1_hist_chap PF04729.8 EME77626.1 - 3.2e-69 231.4 0.0 4.4e-69 231.0 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Lgl_C PF08596.5 EME77627.1 - 3.6e-118 394.4 0.0 1.2e-117 392.7 0.0 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EME77627.1 - 6.5e-05 22.6 3.4 0.049 13.5 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME77627.1 - 0.15 11.5 0.3 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TBCC PF07986.7 EME77628.1 - 8.3e-32 109.1 1.0 1.7e-31 108.1 0.2 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C DUF4463 PF14703.1 EME77628.1 - 0.16 12.5 0.0 0.84 10.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) Lactamase_B_3 PF13483.1 EME77629.1 - 2.9e-06 27.0 0.0 7.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EME77629.1 - 0.0056 16.2 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EMG1 PF03587.9 EME77632.1 - 2.5e-78 262.0 0.0 2.9e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase COG5 PF10392.4 EME77633.1 - 1.1e-37 128.8 1.6 1.1e-37 128.8 1.1 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Rpp20 PF12328.3 EME77633.1 - 0.063 12.9 3.3 0.11 12.1 0.6 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P SPT16 PF08644.6 EME77633.1 - 0.19 11.5 2.7 5.7 6.7 0.1 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Microtub_assoc PF07989.6 EME77634.1 - 3.1e-20 71.7 11.3 3.1e-20 71.7 7.8 13.6 7 4 6 15 15 15 1 Microtubule associated Reo_sigmaC PF04582.7 EME77634.1 - 0.00014 21.2 71.2 0.0015 17.7 1.9 8.5 2 1 8 11 11 11 8 Reovirus sigma C capsid protein Spc7 PF08317.6 EME77634.1 - 0.0029 16.3 20.3 0.0029 16.3 14.1 10.3 1 1 10 12 12 12 5 Spc7 kinetochore protein bZIP_1 PF00170.16 EME77634.1 - 0.0072 16.2 1.1 0.0072 16.2 0.8 16.5 15 6 4 19 19 19 2 bZIP transcription factor AAA_13 PF13166.1 EME77634.1 - 0.12 10.8 160.0 0.3 9.4 13.9 6.5 1 1 5 6 6 6 0 AAA domain SAM_2 PF07647.12 EME77636.1 - 1.1e-06 28.3 0.1 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EME77636.1 - 0.00065 19.8 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Glyco_hydro_16 PF00722.16 EME77637.1 - 2e-07 30.4 0.2 6.7e-07 28.7 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Mito_carr PF00153.22 EME77638.1 - 1.7e-56 187.9 0.9 1.2e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BLOC1_2 PF10046.4 EME77639.1 - 0.059 13.5 0.1 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COesterase PF00135.23 EME77640.1 - 2.3e-84 284.0 0.4 2.7e-84 283.7 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME77640.1 - 2.7e-09 36.8 0.0 9.2e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME77640.1 - 0.0018 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EME77640.1 - 0.14 10.7 0.0 0.48 9.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Peptidase_C14 PF00656.17 EME77641.1 - 2.4e-72 243.5 0.0 2.8e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Caspase domain PAT1 PF09770.4 EME77641.1 - 1.1 7.3 17.7 1.4 7.1 12.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EME77641.1 - 8.1 5.7 14.7 10 5.4 10.2 1.2 1 0 0 1 1 1 0 Vta1 like HNH PF01844.18 EME77642.1 - 0.0042 16.9 2.9 0.0091 15.8 2.0 1.6 1 0 0 1 1 1 1 HNH endonuclease SGT1 PF07093.6 EME77643.1 - 1.9e-122 409.6 20.7 1.9e-120 403.0 14.3 2.0 1 1 0 1 1 1 1 SGT1 protein FAM176 PF14851.1 EME77643.1 - 0.061 13.0 2.0 0.12 12.0 1.4 1.5 1 0 0 1 1 1 0 FAM176 family Tannase PF07519.6 EME77644.1 - 2e-97 326.8 0.0 2.5e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EME77644.1 - 3.8e-07 30.2 0.0 1.3e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME77644.1 - 4.9e-05 22.6 0.0 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME77644.1 - 0.0019 17.9 0.1 1.7 8.3 0.0 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME77644.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.23 EME77645.1 - 4.9e-94 315.9 0.0 7.9e-82 275.6 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EME77645.1 - 2.2e-06 27.3 0.2 1.4e-05 24.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DivIVA PF05103.8 EME77646.1 - 0.0015 18.5 3.4 0.0017 18.3 2.3 1.1 1 0 0 1 1 1 1 DivIVA protein DUF883 PF05957.8 EME77646.1 - 0.055 13.8 4.7 0.079 13.3 3.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Ribosomal_60s PF00428.14 EME77646.1 - 0.099 13.0 10.4 0.12 12.8 7.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Borrelia_P83 PF05262.6 EME77646.1 - 0.16 10.1 6.3 0.18 10.0 4.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Seryl_tRNA_N PF02403.17 EME77646.1 - 0.46 10.5 3.7 0.67 9.9 2.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_B PF00430.13 EME77646.1 - 0.96 9.2 7.1 1.3 8.8 4.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) YtxH PF12732.2 EME77646.1 - 5.8 7.3 9.4 30 5.0 6.5 2.1 1 1 0 1 1 1 0 YtxH-like protein Cellulase PF00150.13 EME77647.1 - 1.5e-10 40.7 0.0 2.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pyridoxal_deC PF00282.14 EME77647.1 - 0.054 11.9 0.1 0.081 11.3 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain RNA_polI_A34 PF08208.6 EME77648.1 - 7.9e-18 64.8 19.0 7.9e-18 64.8 13.2 5.6 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CENP-B_dimeris PF09026.5 EME77648.1 - 4.7 7.5 22.4 1.4 9.2 4.1 3.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain MobB PF03205.9 EME77649.1 - 1.9e-08 34.1 0.0 3.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 EME77649.1 - 2e-07 30.9 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 FAD_binding_3 PF01494.14 EME77650.1 - 2e-21 76.4 1.5 1.5e-20 73.6 1.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME77650.1 - 4.3e-09 35.7 2.8 0.00026 19.9 0.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME77650.1 - 4.4e-06 26.6 0.3 1.2e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME77650.1 - 9.5e-06 25.6 0.7 0.00022 21.1 0.5 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME77650.1 - 2e-05 23.8 0.5 0.0062 15.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EME77650.1 - 0.00071 18.5 0.8 0.0015 17.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EME77650.1 - 0.0025 16.5 0.5 0.56 8.7 0.3 2.7 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EME77650.1 - 0.0093 15.7 0.6 1.9 8.2 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EME77650.1 - 0.012 15.9 0.3 0.037 14.4 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EME77650.1 - 0.014 14.2 0.0 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.1 EME77650.1 - 0.021 14.8 0.1 0.067 13.2 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME77650.1 - 0.024 13.1 0.3 0.2 10.0 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EME77650.1 - 0.025 13.5 0.2 10 4.8 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 EME77650.1 - 0.068 12.2 0.1 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family DUF134 PF02001.11 EME77650.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF134 TPP_enzyme_C PF02775.16 EME77652.1 - 6.8e-16 58.1 0.0 2e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EME77652.1 - 6.6e-13 48.5 0.0 1.3e-10 41.0 0.0 2.8 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME77652.1 - 4e-12 46.0 0.0 9.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CBS PF00571.23 EME77653.1 - 1.3e-14 53.7 3.3 2e-06 27.4 0.1 5.4 5 0 0 5 5 5 4 CBS domain TOM_sub5 PF15178.1 EME77653.1 - 0.034 13.8 0.1 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog zf-TAZ PF02135.11 EME77654.1 - 1.5 8.8 5.4 4.3 7.4 3.7 1.8 1 1 0 1 1 1 0 TAZ zinc finger MFS_1 PF07690.11 EME77656.1 - 2.7e-34 118.4 23.1 4.8e-17 61.6 8.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME77656.1 - 4.2e-07 28.9 21.6 1.1e-05 24.1 6.7 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EME77656.1 - 0.0004 20.1 0.8 0.026 14.3 0.1 2.8 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.15 EME77656.1 - 0.018 13.1 4.5 0.014 13.5 0.2 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EME77657.1 - 1.9e-35 122.2 17.9 1.9e-35 122.2 12.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S41 PF03572.13 EME77659.1 - 3.3e-08 33.1 0.0 9.4e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 ABC_tran PF00005.22 EME77660.1 - 1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EME77660.1 - 0.00014 21.1 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EME77660.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PP-binding PF00550.20 EME77661.1 - 5.9e-14 52.0 0.1 7.6e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2294 PF10057.4 EME77661.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) DUF4285 PF14113.1 EME77661.1 - 0.12 12.3 0.1 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4285) DUF3638 PF12340.3 EME77662.1 - 6.6e-99 329.5 0.3 1.7e-98 328.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EME77662.1 - 7.9e-18 63.2 1.7 2e-17 61.9 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PBP PF01161.15 EME77663.1 - 1.7e-13 50.6 0.1 2.3e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF912 PF06024.7 EME77664.1 - 0.059 13.4 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tweety PF04906.8 EME77664.1 - 0.58 8.5 3.6 1.3 7.3 2.5 1.6 1 1 0 1 1 1 0 Tweety Whi5 PF08528.6 EME77666.1 - 2.3e-09 36.5 0.1 4.2e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Sec31 PF11549.3 EME77666.1 - 1.8 8.2 6.1 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein transport protein SEC31 Metallopep PF12044.3 EME77668.1 - 3.2e-169 562.8 0.0 5e-169 562.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family DDE_Tnp_4 PF13359.1 EME77672.1 - 5.2e-06 26.1 0.0 5.7e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank PF00023.25 EME77673.1 - 4.4e-09 35.6 0.0 4.6e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EME77673.1 - 6.1e-07 29.4 0.0 2.7e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME77673.1 - 6.6e-07 28.9 0.0 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EME77673.1 - 9.3e-06 25.8 0.0 2.4e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME77673.1 - 0.0011 19.4 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SGL PF08450.7 EME77674.1 - 2e-20 73.2 0.1 8.4e-20 71.1 0.1 1.9 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EME77674.1 - 3.4e-07 30.2 0.0 1.4e-05 24.9 0.0 2.8 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EME77674.1 - 0.0018 18.1 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 EME77674.1 - 0.05 13.5 0.3 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 NHL repeat NAD_binding_10 PF13460.1 EME77675.1 - 9.7e-16 58.3 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME77675.1 - 4e-15 55.7 0.0 5.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EME77675.1 - 1.6e-14 53.9 0.0 3.3e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME77675.1 - 9.8e-13 47.4 0.0 5.7e-12 44.9 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME77675.1 - 2.8e-07 29.7 0.0 9.6e-06 24.6 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EME77675.1 - 4.3e-07 29.1 0.2 0.0021 17.0 0.1 3.2 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 EME77675.1 - 0.0062 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EME77675.1 - 0.015 14.9 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 KR domain adh_short PF00106.20 EME77675.1 - 0.032 14.1 0.1 0.099 12.5 0.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase PCI PF01399.22 EME77676.1 - 2.3e-10 40.7 0.4 6.6e-10 39.2 0.3 1.8 1 0 0 1 1 1 1 PCI domain Frag1 PF10277.4 EME77678.1 - 4.4e-39 134.1 11.3 4.4e-39 134.1 7.8 2.8 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 EME77679.1 - 2.3e-28 97.7 1.4 1.5e-27 95.1 0.0 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EME77679.1 - 0.0016 17.4 0.2 0.017 14.0 0.0 2.2 1 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EME77679.1 - 0.023 15.3 4.7 2.4 9.0 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Suf PF05843.9 EME77679.1 - 0.25 11.0 4.5 1.9 8.1 3.1 2.8 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) KdpC PF02669.10 EME77683.1 - 0.019 14.6 0.2 0.058 13.0 0.0 1.8 2 0 0 2 2 2 0 K+-transporting ATPase, c chain F-box-like_2 PF13013.1 EME77683.1 - 0.028 14.1 0.1 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain DAG1 PF05454.6 EME77684.1 - 0.32 10.1 3.5 0.74 8.9 1.3 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TauD PF02668.11 EME77685.1 - 1.2e-34 120.1 0.0 1.8e-34 119.6 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.1 EME77686.1 - 7.3e-14 52.2 0.0 1.3e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME77686.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sulfatase PF00884.18 EME77687.1 - 5e-60 203.2 1.7 5e-60 203.2 1.2 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EME77687.1 - 4.4e-05 22.9 0.5 8.3e-05 22.0 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EME77687.1 - 0.00091 17.7 0.0 0.033 12.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF229) Acetyltransf_13 PF13880.1 EME77688.1 - 2.7e-19 68.6 0.2 6.4e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EME77688.1 - 1e-15 56.9 3.4 2.3e-15 55.8 2.4 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EME77688.1 - 0.00014 21.8 0.1 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EME77688.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EME77688.1 - 0.0088 16.1 0.0 0.029 14.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EME77688.1 - 0.016 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 NinG PF05766.7 EME77688.1 - 0.073 12.8 0.6 5.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Ureidogly_hydro PF04115.7 EME77689.1 - 3.1e-48 163.2 0.0 4.1e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase CLP_protease PF00574.18 EME77691.1 - 3.5e-74 248.3 0.0 4.3e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.11 EME77691.1 - 0.043 12.6 0.0 0.082 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DnaJ PF00226.26 EME77693.1 - 5e-10 38.9 2.4 1.1e-09 37.8 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.20 EME77695.1 - 8.5e-31 107.1 2.1 1.1e-30 106.7 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME77695.1 - 8.9e-28 97.6 0.0 1.1e-27 97.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME77695.1 - 2.6e-15 56.5 1.0 3.6e-15 56.0 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME77695.1 - 0.0012 18.3 0.3 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EME77695.1 - 0.071 12.1 1.0 0.14 11.2 0.1 1.9 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.6 EME77695.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) 3HCDH_N PF02737.13 EME77695.1 - 0.3 10.7 2.0 0.53 9.9 1.4 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.13 EME77697.1 - 3.4e-08 33.2 12.5 7.6e-08 32.1 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME77697.1 - 2e-06 26.8 2.1 2.8e-06 26.3 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EME77697.1 - 5.1e-05 23.3 13.1 0.00011 22.2 1.1 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME77697.1 - 0.00036 20.6 1.5 0.00036 20.6 1.0 5.3 5 1 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME77697.1 - 0.0011 19.0 4.0 0.0011 19.0 2.8 4.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EME77697.1 - 0.47 10.6 5.4 11 6.3 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ketoacyl-synt PF00109.21 EME77701.1 - 4.1e-76 255.8 0.0 1.1e-75 254.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EME77701.1 - 9.9e-51 172.9 0.0 1.8e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EME77701.1 - 1.7e-32 111.7 3.1 4.9e-32 110.2 2.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EME77701.1 - 1.3e-24 87.6 0.0 8.8e-24 84.9 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EME77701.1 - 1.6e-22 79.5 6.5 2.4e-12 46.9 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EME77701.1 - 7.3e-08 32.5 1.0 0.00018 21.4 0.0 3.0 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME77701.1 - 2.1e-05 24.3 0.0 0.23 11.1 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EME77701.1 - 7e-05 21.9 0.1 0.00019 20.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EME77701.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RHH_3 PF12651.2 EME77701.1 - 0.12 12.0 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain Prefoldin PF02996.12 EME77702.1 - 1.5e-33 114.9 0.5 2.3e-33 114.4 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 EME77702.1 - 0.001 18.7 0.4 0.031 14.0 0.0 2.3 2 0 0 2 2 2 1 Hr1 repeat Prefoldin_2 PF01920.15 EME77702.1 - 0.027 14.2 1.0 0.37 10.5 0.1 2.4 2 1 0 2 2 2 0 Prefoldin subunit DUF4201 PF13870.1 EME77702.1 - 0.13 11.6 1.9 1.4 8.3 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) SlyX PF04102.7 EME77702.1 - 0.45 10.9 2.1 7.5 7.0 0.1 2.7 3 0 0 3 3 3 0 SlyX Med14 PF08638.6 EME77703.1 - 4.1e-56 189.3 0.0 1.2e-55 187.8 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit MED14 ATG22 PF11700.3 EME77704.1 - 2.9e-195 649.3 10.9 3.3e-195 649.1 7.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EME77704.1 - 6.1e-06 25.1 46.7 0.00031 19.5 2.8 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily UL11 PF11094.3 EME77705.1 - 0.08 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein CmcI PF04989.7 EME77707.1 - 0.28 10.4 2.0 9.6 5.4 0.0 2.8 2 1 1 3 3 3 0 Cephalosporin hydroxylase NADH-u_ox-rdase PF10785.4 EME77709.1 - 0.39 11.0 0.1 0.39 11.0 0.1 2.3 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4305 PF14146.1 EME77709.1 - 5.8 6.7 15.4 3.7 7.3 0.5 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4305) Peroxidase_2 PF01328.12 EME77710.1 - 4.8e-07 28.7 1.3 1.3e-06 27.3 0.9 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 CDP-OH_P_transf PF01066.16 EME77712.1 - 1.9e-14 53.7 1.6 3.7e-14 52.8 1.1 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Cullin PF00888.17 EME77713.1 - 4.9e-13 48.4 0.0 7.4e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Cullin family DUF1827 PF08860.5 EME77713.1 - 0.12 12.5 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) MFS_1 PF07690.11 EME77714.1 - 1.4e-33 116.0 31.1 3.4e-33 114.8 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PCMT PF01135.14 EME77715.1 - 1.3e-62 211.1 0.0 1.5e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EME77715.1 - 1.1e-08 35.6 0.0 2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME77715.1 - 2.9e-08 33.4 0.0 5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME77715.1 - 0.00011 21.8 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME77715.1 - 0.00024 20.8 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME77715.1 - 0.00047 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EME77715.1 - 0.0038 16.6 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EME77715.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME77715.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EME77715.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EME77715.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain MTS PF05175.9 EME77715.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EME77715.1 - 0.061 12.4 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EME77715.1 - 0.082 13.7 0.0 0.27 12.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain PrmA PF06325.8 EME77715.1 - 0.095 11.7 0.0 0.15 11.1 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RnfC_N PF13375.1 EME77715.1 - 0.11 12.2 0.2 20 4.9 0.0 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Glyco_hydro_17 PF00332.13 EME77716.1 - 2.8e-06 26.5 3.9 0.00033 19.8 0.1 2.1 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 FAP PF07174.6 EME77716.1 - 0.018 14.3 21.0 0.18 11.1 13.5 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DUF4434 PF14488.1 EME77716.1 - 0.033 13.9 0.1 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Cache_3 PF14827.1 EME77716.1 - 0.22 11.4 1.9 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase DUF2360 PF10152.4 EME77716.1 - 1.6 8.9 6.4 3.2 8.0 4.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Aldo_ket_red PF00248.16 EME77718.1 - 8.7e-69 231.4 0.0 1.1e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PC_rep PF01851.17 EME77722.1 - 0.45 10.8 9.5 9 6.7 0.2 5.5 6 0 0 6 6 6 0 Proteasome/cyclosome repeat adh_short PF00106.20 EME77725.1 - 2.5e-07 30.7 0.0 0.0042 17.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EME77725.1 - 8.4e-06 25.7 0.0 0.00018 21.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GrpE PF01025.14 EME77727.1 - 0.031 13.8 0.9 0.049 13.1 0.6 1.4 1 1 0 1 1 1 0 GrpE YkuI_C PF10388.4 EME77727.1 - 0.04 13.5 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Hexapep PF00132.19 EME77728.1 - 9.5e-13 47.0 10.0 7.6e-11 41.0 2.2 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME77728.1 - 3.3e-10 39.3 4.6 2.8e-08 33.1 1.0 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase zf-C2H2_jaz PF12171.3 EME77729.1 - 1.1e-10 41.3 1.7 1.1e-10 41.3 1.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME77729.1 - 6.3e-06 26.2 0.6 6.3e-06 26.2 0.4 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 EME77729.1 - 0.0014 18.1 1.1 0.0023 17.4 0.2 1.8 2 0 0 2 2 2 1 U1 zinc finger K167R PF08065.7 EME77729.1 - 0.0056 16.7 5.2 0.092 12.8 0.1 2.1 2 0 0 2 2 2 1 K167R (NUC007) repeat zf-C2H2_4 PF13894.1 EME77729.1 - 0.0098 16.1 0.2 0.029 14.6 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 EME77729.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2H2_6 PF13912.1 EME77729.1 - 0.14 12.1 0.2 0.14 12.1 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EME77729.1 - 0.19 11.8 3.1 0.32 11.1 1.4 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EME77729.1 - 0.41 11.0 0.4 0.41 11.0 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Aconitase PF00330.15 EME77730.1 - 7.5e-172 571.9 0.1 1.5e-171 570.9 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME77730.1 - 1.7e-46 157.5 0.0 3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L29e PF01779.12 EME77731.1 - 1e-21 76.5 11.3 1.6e-21 75.9 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family BTB PF00651.26 EME77732.1 - 5.8e-10 39.1 0.0 6.4e-09 35.7 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain RRN3 PF05327.6 EME77732.1 - 0.87 7.6 4.4 1.2 7.1 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EME77732.1 - 4 5.2 7.6 5.2 4.8 5.3 1.3 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.13 EME77733.1 - 3.6e-43 147.5 40.6 4.5e-43 147.2 28.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EME77733.1 - 1.1e-05 24.2 22.1 1.1e-05 24.2 15.3 2.1 2 0 0 2 2 2 1 Spore germination protein CAAD PF14159.1 EME77733.1 - 3 7.5 23.8 0.025 14.2 2.7 3.9 3 2 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Complex1_LYR PF05347.10 EME77735.1 - 7e-09 35.3 0.0 9.8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME77735.1 - 1.2e-06 28.5 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EME77735.1 - 1.8e-06 28.3 0.2 2.7e-06 27.8 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EME77736.1 - 7.4e-18 64.6 0.0 9.6e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME77736.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Cellulase PF00150.13 EME77738.1 - 6.5e-10 38.6 4.7 4.5e-08 32.6 0.6 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DnaJ PF00226.26 EME77739.1 - 2.9e-23 81.3 2.1 2.9e-23 81.3 1.4 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EME77739.1 - 3.1e-20 71.5 15.6 6.4e-09 35.3 0.1 5.6 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 EME77739.1 - 9e-13 47.2 12.8 0.0034 16.9 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME77739.1 - 9e-12 45.1 8.4 6.9e-06 26.3 0.9 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME77739.1 - 2.4e-10 40.7 5.8 0.0029 18.2 0.1 5.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME77739.1 - 1.1e-08 34.3 20.1 0.041 13.7 0.0 9.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME77739.1 - 1.8e-08 34.0 0.1 0.15 11.8 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME77739.1 - 4.4e-07 29.9 6.8 3.8 8.3 0.1 7.7 3 2 6 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME77739.1 - 5.1e-07 29.0 7.6 1.5 8.8 0.5 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME77739.1 - 1.8e-05 24.5 10.1 0.24 11.6 0.1 6.5 7 1 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME77739.1 - 0.019 14.8 1.4 1.2 9.0 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Thioredoxin_8 PF13905.1 EME77739.1 - 0.076 13.1 2.0 0.08 13.0 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin-like SLS PF14611.1 EME77739.1 - 0.1 12.0 0.3 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator TPR_6 PF13174.1 EME77739.1 - 0.22 12.0 22.0 30 5.3 0.1 9.0 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME77739.1 - 0.28 11.1 10.8 5.2 7.0 0.2 5.5 6 2 1 7 7 7 0 Tetratricopeptide repeat DUF1194 PF06707.6 EME77739.1 - 0.28 10.1 4.7 3.8 6.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) IBN_N PF03810.14 EME77740.1 - 7.8e-05 22.5 0.2 0.0017 18.2 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Herpeto_peptide PF14409.1 EME77740.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon zf-C2H2_4 PF13894.1 EME77742.1 - 2.4e-05 24.3 4.2 0.0062 16.7 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME77742.1 - 0.00098 19.3 3.9 0.18 12.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-TFIIB PF13453.1 EME77742.1 - 0.05 12.8 0.3 0.09 11.9 0.2 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-H2C2_2 PF13465.1 EME77742.1 - 0.094 13.0 0.2 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double domain zinc_ribbon_2 PF13240.1 EME77742.1 - 0.13 11.8 0.8 0.37 10.3 0.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EME77742.1 - 0.16 11.9 2.7 8.6 6.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PAT1 PF09770.4 EME77742.1 - 4.3 5.4 17.2 5.1 5.1 11.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GTP_EFTU PF00009.22 EME77744.1 - 1.6e-07 30.9 0.0 4.6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EME77744.1 - 0.041 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 HlyD_3 PF13437.1 EME77744.1 - 0.057 13.7 0.6 0.6 10.4 0.0 2.8 3 0 0 3 3 3 0 HlyD family secretion protein PduV-EutP PF10662.4 EME77744.1 - 0.21 11.0 0.4 23 4.4 0.0 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation HET PF06985.6 EME77745.1 - 2e-07 31.2 0.5 3.4e-07 30.5 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EME77746.1 - 3.4e-45 153.4 0.5 1.2e-44 151.7 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME77746.1 - 4e-09 36.3 0.6 1.5e-08 34.4 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME77746.1 - 5e-08 33.0 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EME77746.1 - 7.1e-07 29.3 0.0 2.4e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EME77746.1 - 2.9e-06 26.3 0.0 8.2e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EME77746.1 - 3.1e-06 27.3 3.1 0.00029 20.9 0.5 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME77746.1 - 0.00016 21.5 0.1 0.00098 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME77746.1 - 0.0005 20.0 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME77746.1 - 0.0005 19.1 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EME77746.1 - 0.00064 19.4 0.6 0.056 13.0 0.0 3.1 2 1 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EME77746.1 - 0.00092 20.0 0.0 0.0051 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME77746.1 - 0.0011 19.1 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EME77746.1 - 0.0015 18.2 0.2 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EME77746.1 - 0.0015 18.1 0.3 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EME77746.1 - 0.0021 17.7 0.0 0.0074 16.0 0.0 1.9 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.7 EME77746.1 - 0.0039 16.3 0.1 0.013 14.6 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EME77746.1 - 0.004 16.7 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EME77746.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME77746.1 - 0.0056 16.3 1.4 0.059 13.0 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 EME77746.1 - 0.0059 15.3 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EME77746.1 - 0.0069 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EME77746.1 - 0.0069 16.7 2.9 1.2 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EME77746.1 - 0.01 15.4 0.2 0.03 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME77746.1 - 0.013 14.8 0.6 0.034 13.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 EME77746.1 - 0.022 14.1 2.6 0.087 12.2 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.1 EME77746.1 - 0.022 14.3 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EME77746.1 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CHD5 PF04420.9 EME77746.1 - 0.025 14.2 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 CHD5-like protein AAA_18 PF13238.1 EME77746.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain Bac_DnaA PF00308.13 EME77746.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 EME77746.1 - 0.053 13.5 0.4 0.41 10.6 0.0 2.6 2 2 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EME77746.1 - 0.061 12.8 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EME77746.1 - 0.068 12.2 1.6 0.89 8.6 0.0 2.7 3 0 0 3 3 3 0 KaiC PAN_4 PF14295.1 EME77747.1 - 2.2e-07 30.4 1.8 5e-07 29.3 1.2 1.7 1 0 0 1 1 1 1 PAN domain tRNA-synt_2b PF00587.20 EME77750.1 - 1.2e-44 151.9 0.3 2.1e-44 151.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME77750.1 - 6.4e-16 58.0 0.1 1.4e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EME77750.1 - 6.8e-14 51.4 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EME77750.1 - 1.1e-11 44.3 0.0 2.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 TGS domain DUF587 PF04532.7 EME77750.1 - 0.13 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF587) QRPTase_C PF01729.14 EME77752.1 - 1.6e-52 177.4 0.0 2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EME77752.1 - 7.8e-24 83.3 0.0 1.9e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF4404 PF14357.1 EME77755.1 - 0.032 14.6 1.7 0.058 13.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Lipase_GDSL_2 PF13472.1 EME77757.1 - 2.8e-10 40.6 0.1 5.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME77757.1 - 1.2e-05 25.3 6.2 0.00017 21.5 4.3 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EME77757.1 - 0.06 13.0 0.3 0.17 11.6 0.2 1.7 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family BTB PF00651.26 EME77758.1 - 0.038 13.9 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain UCH PF00443.24 EME77759.1 - 5.7e-62 209.2 0.2 8.5e-62 208.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME77759.1 - 5.8e-31 108.0 0.0 8.2e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EME77759.1 - 0.00073 19.5 0.2 0.00073 19.5 0.2 2.9 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_4 PF13894.1 EME77761.1 - 1.2e-07 31.5 12.6 0.045 14.1 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EME77761.1 - 5.7e-05 23.2 7.7 0.0047 17.1 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EME77761.1 - 0.84 9.9 4.0 8.9 6.7 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain NadA PF02445.11 EME77762.1 - 0.083 11.6 0.0 0.095 11.4 0.0 1.0 1 0 0 1 1 1 0 Quinolinate synthetase A protein Aldo_ket_red PF00248.16 EME77764.1 - 1.6e-49 168.2 0.0 1.9e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.4 EME77764.1 - 0.035 13.9 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q FAD_binding_3 PF01494.14 EME77765.1 - 1.5e-10 40.6 0.0 1.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME77765.1 - 3.9e-05 23.5 0.0 0.00012 21.9 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME77765.1 - 0.00016 20.6 0.0 0.00069 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME77765.1 - 0.0025 17.7 0.0 0.0036 17.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME77765.1 - 0.0064 15.4 0.1 0.037 12.9 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME77765.1 - 0.022 13.5 0.1 0.053 12.3 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EME77765.1 - 0.042 12.4 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EME77765.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EME77765.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HATPase_c PF02518.21 EME77767.1 - 3.4e-28 97.5 0.0 9.6e-28 96.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME77767.1 - 2.1e-27 95.3 0.3 5.8e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EME77767.1 - 7.1e-14 51.5 1.3 1.8e-13 50.2 0.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EME77767.1 - 0.0013 18.8 7.1 0.42 10.8 0.0 4.4 4 0 0 4 4 4 2 HAMP domain Peptidase_M3 PF01432.15 EME77770.1 - 4.4e-122 408.4 0.0 7.5e-122 407.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EME77770.1 - 0.0036 16.7 0.4 0.0068 15.8 0.3 1.3 1 0 0 1 1 1 1 Peptidase M50B-like ApoO PF09769.4 EME77771.1 - 2.1e-47 160.7 0.1 4.9e-47 159.5 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O HAD_2 PF13419.1 EME77772.1 - 4.9e-28 98.5 0.0 6.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME77772.1 - 8.1e-07 29.6 0.0 4.6e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME77772.1 - 2.1e-05 24.1 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EME77772.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EME77773.1 - 1.1 8.3 3.3 1.7 7.6 2.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein GST_N_3 PF13417.1 EME77774.1 - 2.2e-21 75.8 0.0 6.4e-21 74.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME77774.1 - 9.2e-14 51.1 0.0 6.4e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME77774.1 - 9.2e-08 32.1 0.0 3e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME77774.1 - 0.0046 16.8 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME77774.1 - 0.14 12.6 0.1 0.83 10.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain SPX PF03105.14 EME77775.1 - 4e-27 95.7 0.1 7.2e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 SPX domain zf-RING_6 PF14835.1 EME77775.1 - 0.00053 19.7 10.1 0.0075 16.0 6.5 2.3 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EME77775.1 - 0.00078 19.0 9.2 0.0015 18.1 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME77775.1 - 0.0034 17.0 9.1 0.0071 16.0 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME77775.1 - 0.0044 16.9 12.5 0.0044 16.9 8.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME77775.1 - 0.0063 16.1 10.2 0.0063 16.1 7.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME77775.1 - 0.012 15.4 10.7 0.025 14.4 7.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EME77775.1 - 0.18 11.6 16.9 0.064 13.1 8.4 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EME77775.1 - 0.25 11.2 5.0 0.49 10.2 3.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DNA_ligase_ZBD PF03119.11 EME77775.1 - 0.91 9.2 4.5 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain TauD PF02668.11 EME77776.1 - 4.8e-40 137.8 0.1 5.8e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_zinc_N PF00107.21 EME77779.1 - 1.9e-10 40.3 0.0 7.5e-10 38.4 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME77779.1 - 8.9e-08 31.8 0.2 4.2e-07 29.7 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_C2 PF00648.16 EME77781.1 - 1.2e-18 67.2 0.0 2.3e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EME77781.1 - 1.8e-17 63.3 0.8 3e-16 59.3 0.0 3.1 4 1 0 4 4 4 1 Calpain large subunit, domain III MIT PF04212.13 EME77781.1 - 0.0032 17.2 0.4 0.0076 16.1 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Oxysterol_BP PF01237.13 EME77782.1 - 8.6e-62 208.6 0.1 1.2e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein zf-RING_2 PF13639.1 EME77784.1 - 1.1e-09 37.9 1.8 1.1e-09 37.9 1.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME77784.1 - 2.1e-07 30.9 5.3 2.1e-06 27.7 3.7 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME77784.1 - 5.8e-06 25.8 4.5 2.1e-05 24.0 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME77784.1 - 1e-05 25.1 1.0 3.3e-05 23.5 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME77784.1 - 4.8e-05 23.3 1.1 4.8e-05 23.3 0.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME77784.1 - 0.00029 20.4 0.1 0.00029 20.4 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME77784.1 - 0.0066 16.2 0.6 0.016 15.0 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME77784.1 - 0.028 13.9 0.7 0.069 12.7 0.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EME77784.1 - 0.075 12.5 0.3 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EME77784.1 - 0.1 12.3 0.8 0.34 10.6 0.6 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME77784.1 - 0.23 11.3 1.0 0.6 10.0 0.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING YliH PF10799.3 EME77784.1 - 0.56 9.9 2.0 0.5 10.0 0.2 1.8 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) ADH_N_assoc PF13823.1 EME77784.1 - 1.1 8.9 3.5 2.6 7.7 2.4 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated zf-P11 PF03854.9 EME77784.1 - 1.4 8.4 4.6 0.53 9.7 1.3 1.7 2 0 0 2 2 2 0 P-11 zinc finger HoxA13_N PF12284.3 EME77785.1 - 0.013 15.6 2.3 0.015 15.4 1.6 1.1 1 0 0 1 1 1 0 Hox protein A13 N terminal DUF3597 PF12200.3 EME77785.1 - 0.12 12.8 2.0 0.13 12.6 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) APH PF01636.18 EME77786.1 - 2.2e-16 60.3 0.0 6.6e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family UDG PF03167.14 EME77788.1 - 1.9e-25 89.1 0.1 2.8e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cyt-b5 PF00173.23 EME77789.1 - 5.5e-10 38.8 0.0 9.5e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TarH PF02203.10 EME77789.1 - 2.8 7.7 4.6 5.3 6.8 0.1 2.9 3 0 0 3 3 3 0 Tar ligand binding domain homologue Peptidase_C6 PF00851.13 EME77790.1 - 0.087 11.4 0.1 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase Thioredoxin PF00085.15 EME77792.1 - 2.8e-67 222.9 5.2 7.9e-33 112.2 0.1 4.6 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EME77792.1 - 2.8e-50 170.7 0.3 1.2e-34 119.6 0.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME77792.1 - 1.4e-14 53.8 1.0 1.6e-05 24.8 0.0 4.5 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EME77792.1 - 5.5e-12 45.8 5.4 0.00012 22.2 0.1 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME77792.1 - 5.9e-12 45.5 0.0 0.002 18.1 0.0 4.8 4 1 0 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 EME77792.1 - 4.7e-11 42.0 1.0 6.8e-11 41.5 0.1 1.6 2 0 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 EME77792.1 - 2.5e-07 30.4 1.3 0.029 14.0 0.1 3.2 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EME77792.1 - 6.4e-07 29.0 3.2 0.014 14.9 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EME77792.1 - 0.013 15.2 0.2 0.11 12.2 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin domain DUF3692 PF12469.3 EME77792.1 - 0.36 11.0 2.1 0.83 9.9 0.4 2.3 2 0 0 2 2 2 0 CRISPR-associated protein BEX PF04538.7 EME77792.1 - 1.1 9.4 8.6 2.1 8.5 6.0 1.5 1 0 0 1 1 1 0 Brain expressed X-linked like family Rsa3 PF14615.1 EME77793.1 - 2.3e-19 68.3 0.1 2.7e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Ribosome-assembly protein 3 zf-CHC2 PF01807.15 EME77793.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 CHC2 zinc finger Ytp1 PF10355.4 EME77794.1 - 4.8e-101 337.5 10.2 4.8e-101 337.5 7.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EME77794.1 - 3e-21 74.9 6.3 3e-21 74.9 4.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) ICMT PF04140.9 EME77794.1 - 0.02 15.0 0.1 0.063 13.4 0.1 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Arfaptin PF06456.8 EME77796.1 - 0.027 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain GtrA PF04138.9 EME77796.1 - 0.032 14.1 8.5 0.067 13.1 5.9 1.5 1 0 0 1 1 1 0 GtrA-like protein DASH_Dam1 PF08653.5 EME77797.1 - 3.6e-26 90.6 0.6 4.8e-26 90.2 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 EME77798.1 - 3.9e-45 153.1 0.0 6.5e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME77798.1 - 8.9e-15 54.5 0.2 2.5e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EME77798.1 - 7.1e-09 35.7 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Glyco_hydro_43 PF04616.9 EME77799.1 - 1.6e-30 106.1 0.4 2.2e-30 105.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TPP_enzyme_N PF02776.13 EME77799.1 - 0.058 12.8 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PH PF00169.24 EME77800.1 - 1.6e-10 41.1 0.0 3.4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EME77800.1 - 0.0023 15.5 0.4 0.0032 15.0 0.3 1.2 1 0 0 1 1 1 1 Prominin Spc7 PF08317.6 EME77800.1 - 0.0077 14.9 1.4 0.012 14.3 1.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein eIF-3c_N PF05470.7 EME77800.1 - 0.016 13.2 0.7 0.024 12.7 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF972 PF06156.8 EME77800.1 - 0.28 11.5 1.0 0.52 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Sugar_tr PF00083.19 EME77801.1 - 2.3e-73 247.3 24.5 2.6e-73 247.1 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME77801.1 - 5.3e-09 35.2 40.9 7.7e-09 34.7 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME77801.1 - 0.00023 19.7 7.5 0.00023 19.7 5.2 2.8 3 1 1 4 4 4 2 MFS/sugar transport protein Pyridoxal_deC PF00282.14 EME77802.1 - 3e-71 239.8 0.0 7e-64 215.5 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EME77802.1 - 4.7e-06 25.9 0.0 6.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EME77802.1 - 2.7e-05 23.0 0.0 5.9e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V PUF PF00806.14 EME77803.1 - 2.7e-15 54.8 0.1 0.11 11.9 0.0 7.9 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat zf-MYND PF01753.13 EME77804.1 - 1.6e-09 37.4 17.6 4.5e-09 36.0 10.7 2.7 2 0 0 2 2 2 1 MYND finger ECH PF00378.15 EME77805.1 - 9.7e-54 182.0 0.0 1.2e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 EME77806.1 - 7.4e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77806.1 - 5.9e-14 51.7 0.0 8.9e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME77806.1 - 2.8e-05 23.2 0.0 6.6e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME77806.1 - 0.00018 21.3 0.1 0.00036 20.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EME77806.1 - 0.00078 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.14 EME77807.1 - 8.7e-43 146.7 0.0 1.1e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME77807.1 - 0.0036 17.2 0.0 0.0085 16.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME77807.1 - 0.017 15.2 0.1 0.072 13.1 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME77807.1 - 0.065 13.1 0.2 0.67 9.7 0.2 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 EME77810.1 - 1.7e-23 83.2 0.0 1.9e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EME77811.1 - 1e-29 103.4 17.3 2.8e-22 78.9 0.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME77811.1 - 3.2e-22 78.7 23.2 3.2e-22 78.7 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF106 PF01956.11 EME77811.1 - 3.1 7.3 5.8 12 5.3 2.5 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 Cupin_2 PF07883.6 EME77812.1 - 6.7e-07 28.7 0.0 0.0088 15.5 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Peroxidase_2 PF01328.12 EME77813.1 - 1.1e-12 47.2 0.3 2.3e-12 46.2 0.2 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 F-box PF00646.28 EME77814.1 - 4.5e-05 22.9 1.5 0.00014 21.4 1.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME77814.1 - 0.0053 16.4 0.6 0.013 15.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like ubiquitin PF00240.18 EME77815.1 - 8e-48 159.7 0.5 3.1e-24 84.1 0.2 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EME77815.1 - 5.7e-27 93.1 0.0 4.1e-13 48.8 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME77815.1 - 2.1e-06 27.8 0.2 0.00027 21.1 0.0 2.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.4 EME77815.1 - 1.4e-05 25.1 0.1 0.065 13.4 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EME77815.1 - 0.00024 20.9 0.3 0.88 9.4 0.1 2.9 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EME77815.1 - 0.017 14.8 0.2 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 Telomere stability and silencing MerB PF03243.10 EME77815.1 - 0.1 12.4 0.1 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Alkylmercury lyase Pkinase PF00069.20 EME77816.1 - 3.2e-07 29.7 0.6 7.2e-07 28.6 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77816.1 - 0.00022 20.3 0.1 0.0014 17.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME77816.1 - 0.063 12.2 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CENP-F_N PF10481.4 EME77816.1 - 0.083 12.2 0.2 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain PRTase_2 PF15609.1 EME77816.1 - 0.1 11.8 0.9 6.3 6.0 0.2 2.6 2 1 1 3 3 3 0 Phosphoribosyl transferase HSP9_HSP12 PF04119.7 EME77817.1 - 1.3e-20 73.1 9.7 1.7e-20 72.8 4.1 2.0 1 1 1 2 2 2 2 Heat shock protein 9/12 AMMECR1 PF01871.12 EME77819.1 - 3.2e-39 133.8 0.0 2.4e-38 130.9 0.0 1.9 2 0 0 2 2 2 1 AMMECR1 FAD_binding_4 PF01565.18 EME77820.1 - 1.7e-25 89.1 1.1 2.8e-25 88.4 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME77820.1 - 1.5e-12 47.1 0.1 4.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Aldose_epim PF01263.15 EME77821.1 - 6.2e-63 212.6 0.0 7.9e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_18 PF00704.23 EME77827.1 - 1.2e-99 334.0 0.6 1.4e-99 333.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Gaa1 PF04114.9 EME77828.1 - 5.2e-97 325.6 3.2 5.9e-97 325.4 1.6 1.5 2 0 0 2 2 2 1 Gaa1-like, GPI transamidase component TBPIP PF07106.8 EME77829.1 - 1.7e-20 73.2 11.3 2.9e-20 72.5 7.8 1.4 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Not3 PF04065.10 EME77829.1 - 0.0019 17.5 1.3 0.0019 17.5 0.9 2.1 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component Filament PF00038.16 EME77829.1 - 0.026 13.9 7.1 0.035 13.5 4.9 1.2 1 0 0 1 1 1 0 Intermediate filament protein HTH_12 PF08461.5 EME77829.1 - 0.042 13.5 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF641 PF04859.7 EME77829.1 - 0.058 13.1 5.2 0.042 13.5 2.2 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EME77829.1 - 0.095 13.0 7.7 12 6.3 4.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) H-kinase_dim PF02895.9 EME77829.1 - 0.12 12.7 0.8 7.9 6.8 0.2 2.4 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Fe-S_biosyn PF01521.15 EME77829.1 - 0.15 11.9 1.9 5.6 6.9 0.0 3.1 2 1 1 3 3 3 0 Iron-sulphur cluster biosynthesis bZIP_2 PF07716.10 EME77829.1 - 0.24 11.2 5.8 1.1 9.1 0.4 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Piwi PF02171.12 EME77831.1 - 1.1e-72 244.6 0.0 1.5e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EME77831.1 - 3.3e-18 64.7 0.1 8.1e-18 63.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EME77831.1 - 7.9e-16 57.5 1.2 1.6e-15 56.5 0.8 1.5 1 0 0 1 1 1 1 PAZ domain Pyridoxal_deC PF00282.14 EME77833.1 - 5.3e-31 107.4 0.0 7.3e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EME77833.1 - 0.00015 21.0 0.1 0.00027 20.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EME77833.1 - 0.0003 19.6 0.0 0.00056 18.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 EME77833.1 - 0.001 17.6 0.0 0.0023 16.4 0.0 1.5 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DegT_DnrJ_EryC1 PF01041.12 EME77833.1 - 0.0048 15.9 0.2 0.0086 15.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EME77833.1 - 0.0074 15.2 0.0 0.016 14.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cpn60_TCP1 PF00118.19 EME77834.1 - 1.2e-150 502.3 0.1 1.4e-150 502.1 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UNC-50 PF05216.8 EME77837.1 - 2.9e-85 285.1 8.0 3.6e-85 284.8 5.6 1.0 1 0 0 1 1 1 1 UNC-50 family Glyco_hydro_44 PF12891.2 EME77837.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Suf PF05843.9 EME77838.1 - 2.5e-68 230.8 0.0 9.1e-65 219.1 0.0 2.7 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EME77838.1 - 1.2e-05 25.5 0.0 0.73 10.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME77838.1 - 5.8e-05 23.3 0.1 0.13 12.9 0.0 4.8 4 2 1 5 5 5 1 Tetratricopeptide repeat Cytokin_check_N PF10407.4 EME77838.1 - 0.067 12.8 0.5 9.2 5.9 0.0 2.7 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus F-box PF00646.28 EME77840.1 - 1.4e-07 30.9 1.0 3e-07 29.8 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME77840.1 - 0.0011 18.6 0.4 0.0027 17.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like I-set PF07679.11 EME77841.1 - 0.013 15.3 0.1 11 5.9 0.0 4.6 4 0 0 4 4 4 0 Immunoglobulin I-set domain Peptidase_C12 PF01088.16 EME77842.1 - 9.2e-51 172.0 0.0 6.3e-50 169.3 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HCV_NS4b PF01001.14 EME77843.1 - 0.068 12.5 0.1 0.24 10.7 0.1 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b AIG1 PF04548.11 EME77844.1 - 0.066 12.3 0.0 0.27 10.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family HEAT_2 PF13646.1 EME77845.1 - 1e-23 83.3 14.7 2e-09 37.5 0.1 8.4 3 3 2 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 EME77845.1 - 4.4e-22 77.9 17.5 4.7e-09 36.4 0.1 10.9 10 1 3 13 13 13 4 HEAT-like repeat HEAT PF02985.17 EME77845.1 - 2.4e-21 73.8 17.4 6.4e-05 22.7 0.0 12.5 13 0 0 13 13 13 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EME77845.1 - 4.5e-10 39.7 0.2 0.013 15.8 0.0 6.9 7 2 2 9 9 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EME77845.1 - 6e-09 35.5 6.8 0.0075 15.6 0.0 5.8 4 2 3 7 7 7 4 CLASP N terminal Arm PF00514.18 EME77845.1 - 4.9e-06 26.1 12.5 0.051 13.4 0.1 6.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EME77845.1 - 5.3e-06 26.2 0.0 0.017 14.7 0.0 5.1 6 1 1 7 7 6 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EME77845.1 - 5.9e-05 21.5 0.1 0.035 12.4 0.0 4.0 2 1 2 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.2 EME77845.1 - 0.00076 19.3 6.7 20 4.9 0.1 6.6 5 3 2 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EME77845.1 - 0.0024 16.2 1.4 0.21 9.8 0.0 3.6 2 2 0 3 3 3 1 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 EME77845.1 - 0.0033 16.2 0.0 0.0033 16.2 0.0 4.2 6 1 0 6 6 6 1 RNAPII transcription regulator C-terminal V-ATPase_H_N PF03224.9 EME77845.1 - 0.0052 15.9 5.0 5.3 6.0 1.2 4.3 3 1 0 3 3 3 1 V-ATPase subunit H TFCD_C PF12612.3 EME77845.1 - 0.008 15.6 1.5 0.12 11.8 0.0 3.8 4 1 0 4 4 4 1 Tubulin folding cofactor D C terminal DUF4439 PF14530.1 EME77845.1 - 0.057 13.9 1.9 3.1 8.2 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4439) IBN_N PF03810.14 EME77845.1 - 0.061 13.2 5.0 0.24 11.3 0.0 4.4 6 0 0 6 6 5 0 Importin-beta N-terminal domain Bromodomain PF00439.20 EME77846.1 - 7.2e-17 61.0 0.3 1.6e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EME77846.1 - 3.6e-09 36.2 0.0 1.1e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated PBP1_TM PF14812.1 EME77846.1 - 3.2 8.1 22.5 0.076 13.3 0.9 4.5 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VanZ PF04892.7 EME77847.1 - 1.2e-08 34.9 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 VanZ like family Mon1 PF03164.9 EME77849.1 - 2.7e-121 405.0 0.0 3.2e-121 404.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 EME77850.1 - 8e-101 336.8 0.0 2.5e-100 335.2 0.0 1.9 1 0 0 1 1 1 1 Dopey, N-terminal RR_TM4-6 PF06459.7 EME77851.1 - 0.22 11.4 1.6 0.26 11.1 1.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ARID PF01388.16 EME77852.1 - 6.5e-18 64.3 2.1 1e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain COX6B PF02297.12 EME77853.1 - 5.4e-23 80.8 2.6 6.6e-23 80.5 1.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EME77853.1 - 0.091 12.8 0.5 0.16 12.0 0.3 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TPR_11 PF13414.1 EME77854.1 - 3.2e-07 29.9 23.4 0.0076 15.8 0.1 6.3 7 1 0 7 7 7 4 TPR repeat Zn_clus PF00172.13 EME77854.1 - 3.2e-07 30.1 6.7 6e-07 29.2 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.23 EME77854.1 - 1.6e-06 27.4 18.6 0.27 10.9 0.1 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EME77854.1 - 0.00033 20.2 3.6 8.4 6.4 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME77854.1 - 0.00046 20.1 5.6 2.4 8.5 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME77854.1 - 0.00062 20.3 0.2 0.00062 20.3 0.1 7.5 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME77854.1 - 0.0036 17.2 19.2 0.12 12.3 0.5 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME77854.1 - 0.0083 15.8 9.2 9.2 6.3 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME77854.1 - 0.011 15.5 20.8 1.2 9.2 0.0 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.2 EME77854.1 - 0.019 14.7 0.1 0.36 10.6 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 EME77854.1 - 0.058 13.7 16.3 0.27 11.5 0.3 5.3 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME77854.1 - 1.3 9.8 23.9 37 5.3 0.1 9.1 8 2 2 10 10 9 0 Tetratricopeptide repeat Ferritin_2 PF13668.1 EME77855.1 - 1.1e-42 145.2 1.9 1.6e-42 144.7 1.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.9 EME77855.1 - 0.008 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) SnoaL_2 PF12680.2 EME77856.1 - 1.8e-07 31.5 0.0 2.8e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain AHSA1 PF08327.6 EME77856.1 - 0.12 12.4 0.1 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein CP2 PF04516.10 EME77859.1 - 1.1e-85 286.5 0.0 1.6e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 EME77859.1 - 0.038 12.5 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Tektin family Ribosomal_S2 PF00318.15 EME77862.1 - 9e-47 159.0 0.0 1.5e-46 158.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S2 HUN PF08729.5 EME77863.1 - 1.2e-13 50.6 1.5 2.3e-13 49.7 1.1 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 EME77864.1 - 6.4e-31 106.0 0.4 3.8e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EME77864.1 - 1.6e-15 56.4 2.1 3e-15 55.5 1.5 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Lactamase_B PF00753.22 EME77865.1 - 2.5e-19 69.6 1.2 5.1e-19 68.6 0.8 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME77865.1 - 0.0001 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME77865.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain RRM_1 PF00076.17 EME77866.1 - 2.4e-06 27.0 0.0 4.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME77866.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME77866.1 - 0.041 13.7 0.1 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 EME77867.1 - 1.7e-15 56.8 0.7 2.6e-15 56.1 0.5 1.3 1 0 0 1 1 1 1 RF-1 domain DUF3341 PF11821.3 EME77867.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) LepA_C PF06421.7 EME77867.1 - 0.062 13.2 0.3 0.27 11.1 0.5 1.9 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Plant_tran PF04827.9 EME77868.1 - 0.11 11.8 0.1 0.16 11.3 0.0 1.3 1 1 0 1 1 1 0 Plant transposon protein Malate_DH PF12434.3 EME77870.1 - 3.7 7.3 4.8 4.4 7.1 0.3 2.4 2 0 0 2 2 2 0 Malate dehydrogenase enzyme NAD_binding_6 PF08030.7 EME77873.1 - 1.6e-17 63.8 0.0 2.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME77873.1 - 8e-17 61.5 12.3 8e-17 61.5 8.5 2.4 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME77873.1 - 2.3e-13 49.9 0.0 5.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain eIF2A PF08662.6 EME77875.1 - 3.2e-83 278.2 0.1 8.3e-82 273.6 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EME77875.1 - 0.00025 20.8 0.7 1 9.3 0.1 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 EME77875.1 - 0.0098 15.9 0.5 0.0098 15.9 0.4 3.2 3 0 0 3 3 3 1 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.4 EME77875.1 - 0.018 14.3 1.6 1.7 8.0 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 EME77875.1 - 1 9.0 5.3 14 5.4 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ADH_N PF08240.7 EME77877.1 - 7.1e-27 93.3 1.0 1.4e-26 92.3 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME77877.1 - 4e-13 49.0 0.1 6.5e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME77877.1 - 0.00042 21.1 0.1 0.00075 20.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME77877.1 - 0.032 13.8 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PNP_UDP_1 PF01048.15 EME77878.1 - 1.1e-09 37.6 0.3 7.5e-06 25.0 0.1 2.8 1 1 1 2 2 2 2 Phosphorylase superfamily Mito_carr PF00153.22 EME77879.1 - 6.3e-72 237.3 3.9 1.7e-24 85.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med11 PF10280.4 EME77882.1 - 1.4e-24 86.3 0.0 1.9e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein DD_K PF12121.3 EME77882.1 - 0.071 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Dermaseptin WD40 PF00400.27 EME77883.1 - 4.3e-54 178.5 19.7 9.9e-12 44.2 0.6 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EME77883.1 - 4.2e-41 140.3 0.0 5.9e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nucleoporin_N PF08801.6 EME77883.1 - 0.0052 15.5 0.3 0.98 8.0 0.0 3.3 2 2 1 3 3 3 1 Nup133 N terminal like LisH PF08513.6 EME77883.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 0 LisH eIF2A PF08662.6 EME77883.1 - 0.073 12.7 0.0 0.9 9.2 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF3602 PF12223.3 EME77884.1 - 0.096 13.0 4.6 0.23 11.8 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Ribosomal_L31 PF01197.13 EME77886.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 DUF2385 PF09539.5 EME77886.1 - 0.062 13.6 0.3 0.097 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) CAP18_C PF12153.3 EME77886.1 - 0.48 10.1 2.7 3.3 7.4 0.3 2.2 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) DUF2183 PF09949.4 EME77887.1 - 3.1e-10 39.8 0.0 6.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DEAD PF00270.24 EME77889.1 - 3.2e-41 140.6 0.1 4.6e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME77889.1 - 1.8e-23 82.1 0.1 3.4e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EME77889.1 - 0.019 14.0 0.1 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SieB PF14163.1 EME77889.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF2183 PF09949.4 EME77891.1 - 2.1e-33 114.2 0.0 3.6e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) iPGM_N PF06415.8 EME77892.1 - 2.8e-71 239.4 0.0 3.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EME77892.1 - 8.1e-69 231.7 0.2 9.4e-69 231.5 0.2 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EME77892.1 - 8.9e-08 31.8 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME77892.1 - 1.3e-07 31.1 0.0 2.3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 EME77892.1 - 0.0038 15.9 0.3 0.016 13.9 0.1 1.9 2 0 0 2 2 2 1 Alkaline phosphatase SIS_2 PF13580.1 EME77892.1 - 0.096 12.3 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 SIS domain Med9 PF07544.8 EME77893.1 - 5.4e-18 64.4 1.6 8e-18 63.9 0.7 1.6 2 0 0 2 2 1 1 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EME77893.1 - 8.3e-05 22.2 0.8 9.9e-05 22.0 0.5 1.2 1 0 0 1 1 1 1 IncA protein DUF848 PF05852.6 EME77893.1 - 0.00082 19.2 0.8 0.0012 18.7 0.6 1.2 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Fib_alpha PF08702.5 EME77893.1 - 0.0064 16.6 1.5 0.0099 16.0 1.0 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family SNARE PF05739.14 EME77893.1 - 0.0079 15.8 3.6 0.17 11.5 1.1 2.3 2 0 0 2 2 2 1 SNARE domain AAA_27 PF13514.1 EME77893.1 - 0.01 13.5 1.9 0.012 13.3 1.3 1.0 1 0 0 1 1 1 0 AAA domain Acetyltransf_6 PF13480.1 EME77893.1 - 0.012 15.5 2.8 0.016 15.1 1.9 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3450 PF11932.3 EME77893.1 - 0.014 14.7 3.6 0.014 14.7 2.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.11 EME77893.1 - 0.014 15.5 1.8 0.021 15.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 NPV_P10 PF05531.7 EME77893.1 - 0.017 15.3 0.1 0.029 14.6 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EME77893.1 - 0.02 14.0 1.9 0.025 13.7 1.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EME77893.1 - 0.027 14.1 1.7 0.035 13.7 1.2 1.1 1 0 0 1 1 1 0 Mnd1 family TBPIP PF07106.8 EME77893.1 - 0.029 13.9 2.7 0.043 13.3 1.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EME77893.1 - 0.033 13.9 0.7 0.047 13.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 EME77893.1 - 0.039 13.4 0.5 0.053 12.9 0.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Atg14 PF10186.4 EME77893.1 - 0.051 12.5 0.5 0.064 12.1 0.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF148 PF02520.12 EME77893.1 - 0.052 13.3 0.7 0.086 12.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 V_ATPase_I PF01496.14 EME77893.1 - 0.056 11.3 0.5 0.061 11.1 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.4 EME77893.1 - 0.064 13.4 0.4 0.096 12.8 0.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2361 PF10153.4 EME77893.1 - 0.11 12.7 4.0 0.17 12.0 2.7 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) AAA_23 PF13476.1 EME77893.1 - 0.11 12.8 0.6 0.11 12.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain Sec20 PF03908.8 EME77893.1 - 0.12 12.1 0.3 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Sec20 Cauli_AT PF03233.8 EME77893.1 - 0.13 11.9 0.3 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein Occludin_ELL PF07303.8 EME77893.1 - 0.15 12.8 1.4 0.26 12.0 0.9 1.4 1 0 0 1 1 1 0 Occludin homology domain USP8_interact PF08941.5 EME77893.1 - 0.16 11.2 1.2 0.23 10.7 0.8 1.2 1 0 0 1 1 1 0 USP8 interacting DUF972 PF06156.8 EME77893.1 - 0.21 11.9 2.1 0.33 11.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CCDC-167 PF15188.1 EME77893.1 - 0.25 11.3 3.9 0.45 10.4 2.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2721 PF11026.3 EME77893.1 - 0.28 10.8 1.6 0.38 10.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) OmpH PF03938.9 EME77893.1 - 0.31 10.9 3.7 0.43 10.5 2.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4140 PF13600.1 EME77893.1 - 0.41 11.1 7.2 2.7 8.4 5.0 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.3 EME77893.1 - 0.9 9.3 6.7 2.3 8.0 1.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EME77893.1 - 1.5 9.2 8.1 0.25 11.7 1.7 2.2 2 1 1 3 3 2 0 SlyX DivIC PF04977.10 EME77893.1 - 3.4 7.2 8.5 1.2e+02 2.2 6.1 2.1 1 1 0 1 1 1 0 Septum formation initiator AD PF09793.4 EME77894.1 - 0.036 13.9 0.1 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 Anticodon-binding domain ABM PF03992.11 EME77897.1 - 0.00013 21.9 0.0 0.00078 19.4 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.6 EME77897.1 - 0.00023 20.9 0.1 1.2 8.9 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1330) Dabb PF07876.7 EME77897.1 - 0.01 16.2 0.1 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain DUF1971 PF09313.6 EME77897.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Mig-14 PF07395.6 EME77898.1 - 0.025 13.5 0.1 0.029 13.4 0.1 1.1 1 0 0 1 1 1 0 Mig-14 PIP5K PF01504.13 EME77899.1 - 2.2e-84 282.5 0.1 3.1e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Linker_histone PF00538.14 EME77900.1 - 1.5e-20 73.0 0.2 3.1e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Lipocalin_5 PF13924.1 EME77901.1 - 8.8e-25 87.0 0.0 1.1e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Nbl1_Borealin_N PF10444.4 EME77902.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal HEAT_PBS PF03130.11 EME77902.1 - 1.6 9.4 4.2 35 5.2 0.0 2.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Pkinase PF00069.20 EME77903.1 - 1.1e-68 231.2 0.0 1.5e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77903.1 - 2.5e-29 102.1 0.0 3.4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME77903.1 - 3.9e-07 29.3 0.0 6.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME77903.1 - 0.00017 21.4 0.3 0.00033 20.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EME77903.1 - 0.00059 18.9 0.0 0.0017 17.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EME77903.1 - 0.033 13.5 0.0 0.094 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Glyco_hydro_32N PF00251.15 EME77904.1 - 1.2e-40 139.8 3.1 2.8e-40 138.6 2.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EME77904.1 - 4.6e-12 46.1 0.0 9.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EME77904.1 - 0.0068 16.0 0.1 0.04 13.7 0.1 2.5 1 0 0 1 1 1 1 BNR/Asp-box repeat MAPEG PF01124.13 EME77905.1 - 1.5e-07 31.0 5.0 1.5e-07 31.0 3.5 1.5 2 0 0 2 2 2 1 MAPEG family Pkr1 PF08636.5 EME77906.1 - 1e-33 115.2 3.5 1.3e-33 114.8 2.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 EME77906.1 - 0.028 12.7 0.0 0.036 12.4 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family LSM PF01423.17 EME77907.1 - 5.3e-15 54.7 0.0 7e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME77907.1 - 0.00096 19.0 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EME77907.1 - 0.012 15.7 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DTHCT PF08070.6 EME77908.1 - 1.2 9.8 7.7 2 9.1 5.3 1.4 1 1 0 1 1 1 0 DTHCT (NUC029) region KH_1 PF00013.24 EME77909.1 - 4.1e-39 132.0 4.4 2.2e-16 59.2 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EME77909.1 - 1e-28 98.4 10.0 1.2e-11 43.9 1.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EME77909.1 - 2.1e-12 46.4 3.9 0.004 16.6 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EME77909.1 - 8.6e-05 22.0 1.0 0.98 9.1 0.0 3.2 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EME77909.1 - 0.01 15.6 6.7 1 9.2 0.1 3.4 3 1 0 3 3 3 0 NusA-like KH domain BTB PF00651.26 EME77910.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4072 PF13284.1 EME77910.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) HTH_45 PF14947.1 EME77911.1 - 0.028 14.2 0.0 4.3 7.2 0.0 2.6 2 1 0 2 2 2 0 Winged helix-turn-helix Gar1 PF04410.9 EME77912.1 - 7.5e-39 132.6 4.4 7.5e-39 132.6 3.0 2.1 1 1 1 2 2 2 2 Gar1/Naf1 RNA binding region Nol1_Nop2_Fmu PF01189.12 EME77913.1 - 1.9e-16 60.2 0.0 1.4e-10 40.9 0.0 2.5 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EME77913.1 - 0.00031 20.7 0.0 0.00059 19.8 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase F-box-like_2 PF13013.1 EME77914.1 - 0.0066 16.1 0.2 0.013 15.1 0.1 1.8 1 1 0 1 1 1 1 F-box-like domain DUF1049 PF06305.6 EME77915.1 - 0.024 14.1 0.8 0.024 14.1 0.6 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) fn3_3 PF14686.1 EME77917.1 - 7.4e-10 38.8 0.3 1.7e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 EME77917.1 - 3.2e-05 23.6 0.0 7.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III DUF4217 PF13959.1 EME77917.1 - 0.15 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) MFS_1 PF07690.11 EME77918.1 - 5.7e-35 120.6 29.2 7.5e-35 120.2 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 EME77919.1 - 2.2e-81 273.5 0.5 2.7e-81 273.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prenyltrans_2 PF13249.1 EME77919.1 - 9.6e-05 22.7 0.4 0.01 16.2 0.0 3.1 3 1 0 3 3 3 1 Prenyltransferase-like DUF1680 PF07944.7 EME77919.1 - 0.0013 17.1 0.1 0.0017 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 EME77919.1 - 0.0056 16.6 0.2 0.023 14.6 0.0 2.2 3 0 0 3 3 3 1 Prenyltransferase-like Hydrophobin PF01185.13 EME77922.1 - 3.5 8.1 13.7 3.6 8.0 2.7 2.2 1 1 1 2 2 2 0 Fungal hydrophobin MFS_1 PF07690.11 EME77923.1 - 1.8e-36 125.6 29.0 2.7e-36 125.0 20.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CheZ PF04344.8 EME77924.1 - 0.039 13.6 0.1 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Apolipoprotein PF01442.13 EME77925.1 - 0.0029 17.1 3.4 0.0053 16.3 2.3 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain D-ser_dehydrat PF14031.1 EME77926.1 - 4.5e-22 78.0 0.0 9.2e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EME77926.1 - 2.1e-11 43.7 0.0 4.4e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain THUMP PF02926.12 EME77927.1 - 1.6e-12 47.5 0.1 3.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 THUMP domain APH PF01636.18 EME77928.1 - 4.7e-08 33.0 0.0 1.1e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHCH PF06747.8 EME77931.1 - 0.75 9.7 0.1 0.75 9.7 0.1 4.0 5 0 0 5 5 5 0 CHCH domain TFIIA PF03153.8 EME77932.1 - 0.074 12.9 4.8 0.15 11.8 3.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TLD PF07534.11 EME77933.1 - 1.3e-25 90.0 0.0 2.3e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 TLD Aminotran_5 PF00266.14 EME77934.1 - 1.6e-25 89.6 0.0 5.2e-23 81.3 0.0 2.9 1 1 0 1 1 1 1 Aminotransferase class-V Ribosomal_S10 PF00338.17 EME77935.1 - 1.2e-28 98.7 0.7 1.4e-28 98.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4469 PF14734.1 EME77935.1 - 0.11 12.3 0.1 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold CUE PF02845.11 EME77936.1 - 7.8e-08 31.6 0.4 1.9e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 CUE domain TFIIB PF00382.14 EME77937.1 - 0.0075 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat SprT-like PF10263.4 EME77938.1 - 1.5e-47 161.1 2.4 2.6e-47 160.3 1.7 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EME77938.1 - 0.00022 21.4 0.1 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box Zn-ribbon_8 PF09723.5 EME77938.1 - 0.088 12.7 0.8 0.23 11.4 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Peptidase_MA_2 PF13485.1 EME77938.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M30 PF10460.4 EME77938.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M30 Mog1 PF04603.7 EME77939.1 - 1.2e-24 86.8 0.0 1.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein MFS_1 PF07690.11 EME77941.1 - 5.2e-21 74.7 58.8 6.3e-19 67.8 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF63 PF01889.12 EME77941.1 - 0.018 15.1 0.2 0.018 15.1 0.1 2.5 2 1 0 2 2 2 0 Membrane protein of unknown function DUF63 zf-RING_2 PF13639.1 EME77942.1 - 8e-14 51.2 22.1 5.4e-12 45.3 6.8 2.8 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EME77942.1 - 6.2e-11 42.1 17.2 1.2e-08 34.8 6.2 2.8 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME77942.1 - 3.1e-10 39.6 15.1 9.5e-08 31.6 5.8 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME77942.1 - 1.8e-09 37.0 12.7 3.1e-08 33.1 4.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME77942.1 - 1.7e-08 34.0 2.7 0.0001 21.9 1.5 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.20 EME77942.1 - 3.4e-08 32.9 20.0 3.4e-07 29.8 6.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME77942.1 - 1.3e-07 31.3 14.6 8e-05 22.4 5.4 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EME77942.1 - 3.7e-05 23.7 10.7 3.7e-05 23.7 7.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EME77942.1 - 0.0094 15.5 16.5 0.2 11.2 5.9 3.5 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain IBR PF01485.16 EME77942.1 - 0.31 10.9 15.0 1.2 9.0 4.0 2.8 2 0 0 2 2 2 0 IBR domain Prok-RING_4 PF14447.1 EME77942.1 - 0.87 9.1 12.0 0.46 10.0 5.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EME77942.1 - 5.1 7.0 13.4 0.76 9.6 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DEC-1_N PF04625.8 EME77942.1 - 8 5.0 17.9 13 4.3 12.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region eIF3_N PF09440.5 EME77944.1 - 6.1e-46 155.8 1.6 1.2e-45 154.9 1.1 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EME77944.1 - 2.1e-13 50.4 0.1 7.4e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EME77944.1 - 0.013 15.2 0.1 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Img2 PF05046.9 EME77945.1 - 7.6e-20 70.9 0.0 8.3e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EME77945.1 - 0.013 15.2 0.1 0.021 14.6 0.0 1.3 1 1 0 1 1 1 0 Translation initiation factor SUI1 Prp31_C PF09785.4 EME77947.1 - 0.0017 18.7 4.5 0.0024 18.2 3.1 1.2 1 0 0 1 1 1 1 Prp31 C terminal domain PRCC PF10253.4 EME77947.1 - 0.45 11.1 6.7 0.63 10.7 4.6 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF1104 PF06518.6 EME77947.1 - 0.52 10.4 7.6 1.1 9.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF2410 PF10307.4 EME77948.1 - 1.9e-71 239.5 0.0 2.7e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Resolvase PF00239.16 EME77949.1 - 0.0079 16.0 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 1 Resolvase, N terminal domain CH PF00307.26 EME77950.1 - 3.4e-05 23.8 0.0 0.0038 17.2 0.0 3.2 2 1 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EME77950.1 - 0.00074 18.9 2.0 0.86 9.4 0.0 3.6 3 0 0 3 3 3 2 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 EME77950.1 - 0.1 12.2 0.0 12 5.6 0.0 2.9 2 0 0 2 2 2 0 CAMSAP CH domain MRP-S33 PF08293.6 EME77951.1 - 0.056 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit S27 YccV-like PF08755.6 EME77952.1 - 4e-24 84.4 0.2 2.2e-23 82.0 0.1 2.3 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EME77952.1 - 2.3e-11 43.3 0.2 5.3e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EME77952.1 - 6.7e-07 28.9 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME77952.1 - 1.6e-06 27.6 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF2823 PF11034.3 EME77953.1 - 2.1e-19 69.3 8.2 2.8e-19 68.9 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF2765 PF10963.3 EME77953.1 - 0.06 13.3 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) bZIP_2 PF07716.10 EME77956.1 - 3.7e-07 29.8 10.1 9e-07 28.6 7.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EME77956.1 - 4.7e-07 29.6 10.3 1.1e-06 28.4 7.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aa_trans PF01490.13 EME77957.1 - 1.9e-26 92.5 39.6 2.2e-26 92.2 27.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 EME77957.1 - 0.003 17.4 0.5 0.049 13.5 0.1 3.0 2 0 0 2 2 2 1 IBV 3C protein tRNA_m1G_MT PF01746.16 EME77959.1 - 8.3e-35 120.0 0.1 1.1e-31 109.8 0.0 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DEAD PF00270.24 EME77960.1 - 4.2e-22 78.4 0.0 1.2e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 EME77960.1 - 4.9e-20 71.2 0.1 1.2e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.26 EME77960.1 - 2.2e-17 62.6 0.1 9.5e-15 54.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain HRDC PF00570.18 EME77960.1 - 0.0041 16.8 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 EME77960.1 - 0.013 15.3 0.0 0.057 13.2 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 EME77961.1 - 2.1e-37 128.6 43.8 2.7e-31 108.5 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME77961.1 - 3.4e-11 42.3 23.7 6.6e-11 41.4 16.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.10 EME77961.1 - 0.00029 19.7 7.1 0.053 12.2 0.3 2.9 2 1 1 3 3 3 2 PUCC protein MFS_1 PF07690.11 EME77962.1 - 2.5e-45 154.7 62.1 1.7e-41 142.1 31.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME77962.1 - 0.00073 18.2 2.9 0.00073 18.2 2.0 3.4 3 0 0 3 3 3 1 Sugar (and other) transporter Sugar_tr PF00083.19 EME77963.1 - 2e-116 389.2 19.3 4e-116 388.2 13.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME77963.1 - 1.4e-27 96.3 37.6 1.8e-24 86.1 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME77963.1 - 0.012 13.8 8.6 0.017 13.3 3.1 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) tRNA-synt_2 PF00152.15 EME77964.1 - 5.1e-72 242.4 0.0 7.4e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME77964.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EME77964.1 - 0.016 14.7 0.1 0.053 13.1 0.1 1.8 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PAS_7 PF12860.2 EME77964.1 - 0.11 12.5 0.1 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 PAS fold AAA PF00004.24 EME77965.1 - 1.9e-38 131.6 0.0 4.6e-38 130.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EME77965.1 - 6.2e-06 26.0 0.0 3.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EME77965.1 - 7.1e-06 26.2 0.1 0.00018 21.6 0.0 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME77965.1 - 0.00015 20.8 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EME77965.1 - 0.00065 18.5 0.1 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EME77965.1 - 0.0011 18.7 0.1 0.0035 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME77965.1 - 0.0021 18.0 1.1 0.017 15.1 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EME77965.1 - 0.0022 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EME77965.1 - 0.0036 17.0 0.1 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 EME77965.1 - 0.0037 17.1 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EME77965.1 - 0.0038 16.4 0.1 0.0071 15.5 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EME77965.1 - 0.0088 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 EME77965.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME77965.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EME77965.1 - 0.011 15.3 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME77965.1 - 0.016 16.0 0.4 0.13 13.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EME77965.1 - 0.016 14.5 0.1 0.22 10.8 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EME77965.1 - 0.016 15.1 1.2 0.19 11.6 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_14 PF13173.1 EME77965.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME77965.1 - 0.026 14.8 0.0 0.079 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME77965.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EME77965.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 EME77965.1 - 0.13 11.6 0.0 0.43 10.0 0.0 1.9 1 1 1 2 2 2 0 Guanylate kinase PhoH PF02562.11 EME77965.1 - 0.16 11.2 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EME77965.1 - 0.22 10.9 0.0 0.56 9.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain eIF-3c_N PF05470.7 EME77965.1 - 3.7 5.5 4.2 0.55 8.2 0.3 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SYS1 PF09801.4 EME77967.1 - 8.1e-50 168.5 8.8 9.2e-50 168.4 6.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Tim17 PF02466.14 EME77968.1 - 1.7e-13 50.6 11.2 2.4e-13 50.2 7.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UBA_4 PF14555.1 EME77969.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain UBA PF00627.26 EME77969.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Yae1_N PF09811.4 EME77970.1 - 0.018 14.5 5.6 0.16 11.5 0.8 2.3 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Clathrin PF00637.15 EME77971.1 - 2.4e-14 53.1 0.1 6.5e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EME77971.1 - 0.00013 21.6 0.0 0.25 11.2 0.0 4.5 3 1 0 3 3 3 1 WD domain, G-beta repeat Vps39_1 PF10366.4 EME77971.1 - 0.0097 15.9 0.3 0.049 13.6 0.0 2.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 EME77971.1 - 0.029 14.2 2.0 0.061 13.1 1.4 1.5 1 0 0 1 1 1 0 Ring finger domain DUF155 PF02582.9 EME77972.1 - 9.9e-43 146.0 0.0 1.4e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_3 PF05899.7 EME77972.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Fungal_trans PF04082.13 EME77974.1 - 6.3e-14 51.4 0.1 2.1e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME77974.1 - 7e-08 32.2 9.8 1.4e-07 31.2 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MT PF12777.2 EME77974.1 - 0.11 11.1 0.3 0.19 10.4 0.2 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Aldolase_II PF00596.16 EME77975.1 - 6.3e-27 94.3 0.1 9e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1330 PF07045.6 EME77976.1 - 0.027 14.3 0.2 7.7 6.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1330) PEP-utilizers PF00391.18 EME77976.1 - 0.11 12.0 0.0 0.34 10.5 0.1 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain Chordopox_G3 PF06129.7 EME77977.1 - 0.028 14.5 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Ras PF00071.17 EME77979.1 - 3.7e-40 136.9 0.0 4.3e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME77979.1 - 4e-14 53.1 0.0 5.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME77979.1 - 4.5e-05 22.7 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME77979.1 - 0.00046 20.1 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME77979.1 - 0.018 14.4 0.0 0.25 10.7 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PRK PF00485.13 EME77979.1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Glyco_hydro_18 PF00704.23 EME77980.1 - 8.2e-82 275.3 9.7 1.5e-80 271.2 6.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.19 EME77982.1 - 3.6e-41 141.1 23.5 4.4e-41 140.9 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME77982.1 - 9.6e-15 54.1 26.3 9.6e-15 54.1 18.2 1.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyoxalase_2 PF12681.2 EME77983.1 - 2.3e-06 28.1 0.0 5.2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME77983.1 - 0.00065 19.6 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Gly-zipper_YMGG PF13441.1 EME77983.1 - 0.074 12.5 2.8 0.16 11.5 1.9 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper TPR_2 PF07719.12 EME77984.1 - 0.055 13.4 0.1 25 5.1 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat FAT PF02259.18 EME77984.1 - 0.083 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 FAT domain GFA PF04828.9 EME77985.1 - 2.5e-20 72.1 2.5 3.4e-20 71.7 1.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fer4_10 PF13237.1 EME77985.1 - 0.95 9.3 5.7 1.5 8.6 3.2 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain TMEMspv1-c74-12 PF11044.3 EME77986.1 - 0.029 13.8 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein MIP PF00230.15 EME77988.1 - 6.7e-42 143.4 10.0 7.8e-42 143.2 6.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein ADH_zinc_N PF00107.21 EME77989.1 - 1.3e-13 50.6 1.6 1.7e-13 50.2 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME77989.1 - 1.5e-08 34.3 0.8 5.3e-08 32.5 0.0 2.4 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EME77989.1 - 0.023 14.4 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EME77989.1 - 0.038 13.9 1.4 0.064 13.2 1.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 EME77990.1 - 1.5e-63 214.3 0.0 1.9e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME77990.1 - 2e-43 148.3 0.0 2.9e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME77990.1 - 5.6e-09 35.3 0.0 1.7e-06 27.2 0.0 2.6 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EME77990.1 - 0.0036 16.4 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IL10 PF00726.12 EME77990.1 - 0.027 13.7 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Interleukin 10 APH PF01636.18 EME77990.1 - 0.14 11.8 0.1 0.28 10.8 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FHA PF00498.21 EME77993.1 - 1.4e-15 57.0 0.1 2.5e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 FHA domain DUF1777 PF08648.7 EME77993.1 - 0.06 13.0 32.4 0.11 12.2 22.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF566 PF04484.7 EME77993.1 - 3.2 7.1 8.4 3.8 6.9 5.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) LETM1 PF07766.8 EME77994.1 - 7.3e-15 54.7 0.0 6.2e-09 35.2 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein UnbV_ASPIC PF07593.7 EME77995.1 - 0.06 13.0 0.4 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 ASPIC and UnbV Sec7 PF01369.15 EME77996.1 - 3.9e-37 127.7 0.0 8.5e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EME77996.1 - 3.4e-17 62.6 0.0 7.4e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Tektin PF03148.9 EME77996.1 - 0.005 15.4 0.1 0.008 14.7 0.1 1.2 1 0 0 1 1 1 1 Tektin family RrnaAD PF00398.15 EME77997.1 - 0.0011 18.0 0.0 0.0078 15.2 0.0 2.2 3 0 0 3 3 3 1 Ribosomal RNA adenine dimethylase JAB PF01398.16 EME77998.1 - 2.2e-11 43.5 0.0 4.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EME77998.1 - 9e-07 28.8 1.3 1.7e-06 27.9 0.9 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EME77998.1 - 1.4e-05 24.5 0.0 3.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SHMT PF00464.14 EME78000.1 - 1.3e-202 672.5 0.0 1.5e-202 672.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EME78000.1 - 5.5e-06 25.3 0.0 7.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EME78000.1 - 1.8e-05 23.8 0.0 5.8e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME78000.1 - 8.2e-05 21.8 0.0 0.00023 20.4 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_6 PF12697.2 EME78002.1 - 4.6e-29 101.9 0.0 7.1e-29 101.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78002.1 - 5.5e-13 49.0 0.0 1.4e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78002.1 - 3.1e-10 39.9 0.0 7.7e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME78002.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S10 PF00450.17 EME78002.1 - 0.06 12.4 0.0 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase Pro-kuma_activ PF09286.6 EME78003.1 - 7.3e-38 129.8 0.6 5.9e-37 126.8 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME78003.1 - 0.00076 18.7 0.6 0.0012 18.0 0.4 1.3 1 0 0 1 1 1 1 Subtilase family Gpi1 PF05024.10 EME78005.1 - 2.7e-64 216.3 7.9 4.7e-64 215.5 5.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF454 PF04304.8 EME78006.1 - 0.0085 16.0 0.4 0.013 15.4 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF454) zf-CCCH PF00642.19 EME78007.1 - 0.037 13.7 0.2 0.07 12.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2370 PF10176.4 EME78008.1 - 2e-75 253.1 0.7 3e-75 252.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) N6-adenineMlase PF10237.4 EME78009.1 - 9.9e-56 187.8 0.0 1.2e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 EME78009.1 - 0.036 14.0 0.1 0.059 13.4 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.17 EME78010.1 - 1.2e-16 60.0 0.0 5.8e-12 45.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME78010.1 - 4e-12 45.9 0.0 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78010.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME78010.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sec34 PF04136.10 EME78011.1 - 2e-29 102.3 0.4 4.1e-29 101.3 0.3 1.5 1 0 0 1 1 1 1 Sec34-like family IncA PF04156.9 EME78011.1 - 0.83 9.2 5.2 1.8 8.1 3.6 1.6 1 0 0 1 1 1 0 IncA protein S-antigen PF05756.6 EME78012.1 - 0.048 13.6 0.4 0.15 12.0 0.3 1.8 1 0 0 1 1 1 0 S-antigen protein ELM2 PF01448.19 EME78012.1 - 4.8 7.9 5.9 0.68 10.6 0.9 2.0 2 1 0 2 2 2 0 ELM2 domain Adaptin_binding PF10199.4 EME78012.1 - 5 7.3 7.7 15 5.8 5.3 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Nop PF01798.13 EME78013.1 - 5.6e-58 194.4 0.1 1.1e-57 193.6 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EME78013.1 - 1.7e-23 82.1 0.0 3.5e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EME78013.1 - 4.3e-23 81.2 0.2 4.3e-23 81.2 0.2 2.9 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EME78013.1 - 0.00075 19.2 17.9 0.0013 18.4 12.4 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EME78013.1 - 0.15 11.9 11.2 0.24 11.3 7.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3824 PF12868.2 EME78013.1 - 2.9 8.8 9.1 6.2 7.7 6.3 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) GRIM-19 PF06212.7 EME78015.1 - 3.4e-23 81.7 0.1 3.8e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF1686 PF07937.6 EME78015.1 - 0.16 11.5 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) EthD PF07110.6 EME78018.1 - 1.4e-08 35.5 0.1 1.6e-08 35.3 0.1 1.1 1 0 0 1 1 1 1 EthD domain DUF1330 PF07045.6 EME78018.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1330) Peptidase_A4 PF01828.12 EME78019.1 - 3.3e-48 163.5 0.4 4.1e-48 163.2 0.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family DUF4141 PF13605.1 EME78019.1 - 0.038 13.1 0.0 0.098 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Ribonuclease_T2 PF00445.13 EME78020.1 - 1e-44 152.4 0.1 2.2e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family p450 PF00067.17 EME78021.1 - 4.5e-08 32.0 2.6 9.5e-08 30.9 0.4 2.2 2 1 0 2 2 2 1 Cytochrome P450 XPG_I PF00867.13 EME78022.1 - 1.5e-24 85.8 0.2 3.4e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EME78022.1 - 3.6e-20 72.0 0.0 7.6e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EME78022.1 - 1.4e-05 24.6 1.0 1.7e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 EME78022.1 - 0.00068 19.8 0.0 0.0031 17.7 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold ATP-synt_F6 PF05511.6 EME78022.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF2962 PF11176.3 EME78023.1 - 5.4e-47 159.2 2.9 6.1e-47 159.0 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) F-box PF00646.28 EME78024.1 - 0.015 14.9 0.1 0.038 13.6 0.1 1.6 1 0 0 1 1 1 0 F-box domain ubiquitin PF00240.18 EME78027.1 - 1.1e-10 40.7 0.0 1.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-AN1 PF01428.11 EME78027.1 - 3.3e-10 39.6 12.0 4.8e-10 39.1 8.3 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 EME78027.1 - 0.00045 19.8 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME78027.1 - 0.029 14.5 0.0 0.04 14.0 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Glyco_transf_25 PF01755.12 EME78030.1 - 1.2e-08 34.8 0.0 0.00058 19.5 0.0 2.5 2 2 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) CTV_P6 PF06706.6 EME78031.1 - 0.53 9.8 5.8 0.14 11.7 0.9 2.3 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Cyt_c_ox_IV PF12270.3 EME78031.1 - 3.7 7.2 11.1 0.62 9.8 0.1 3.4 4 1 1 5 5 5 0 Cytochrome c oxidase subunit IV DUF1673 PF07895.6 EME78031.1 - 7.1 6.1 9.0 11 5.5 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF2236 PF09995.4 EME78032.1 - 7.2e-29 100.7 3.8 1e-28 100.3 2.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Aminotran_1_2 PF00155.16 EME78033.1 - 2.6e-36 125.3 0.0 3.2e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4066 PF13278.1 EME78036.1 - 1.1e-19 70.2 0.1 2.3e-19 69.2 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EME78036.1 - 1.4e-10 40.8 0.0 1.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family MBOAT PF03062.14 EME78038.1 - 3.1e-48 164.5 15.1 4.9e-48 163.9 10.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EME78038.1 - 0.065 13.3 3.4 0.15 12.1 2.3 1.6 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Actin PF00022.14 EME78039.1 - 5.1e-128 426.8 0.0 5.8e-128 426.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME78039.1 - 0.016 13.8 0.0 1 7.8 0.0 2.4 3 0 0 3 3 3 0 MreB/Mbl protein DNA_pol_A_exo1 PF01612.15 EME78040.1 - 3.7e-39 134.0 0.2 6.2e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EME78040.1 - 1.5e-25 89.3 0.0 3.3e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EME78040.1 - 1.1e-12 47.4 0.0 3.5e-12 45.8 0.0 2.0 1 0 0 1 1 1 1 HRDC domain K_channel_TID PF07941.6 EME78040.1 - 4.5 7.5 9.1 10 6.4 6.3 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain VHS PF00790.14 EME78041.1 - 1e-46 158.0 0.0 5.5e-46 155.7 0.0 2.3 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 EME78041.1 - 1e-24 86.3 0.6 3.7e-24 84.6 0.1 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EME78041.1 - 4.8e-19 68.7 0.1 1e-18 67.7 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Transpos_assoc PF13963.1 EME78043.1 - 9e-05 22.3 0.8 0.052 13.5 0.0 2.6 2 0 0 2 2 2 2 Transposase-associated domain zf-C2H2_4 PF13894.1 EME78043.1 - 0.0062 16.7 9.6 0.18 12.1 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME78043.1 - 0.026 14.8 8.6 2.6 8.5 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Nse PF11789.3 EME78043.1 - 0.076 12.5 3.1 2.4 7.7 0.5 3.3 3 1 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit RCC1 PF00415.13 EME78045.1 - 2.3e-31 107.7 0.1 6.4e-07 29.4 0.0 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EME78045.1 - 1.8e-14 52.9 23.6 4e-12 45.4 0.3 5.8 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Transgly PF00912.17 EME78045.1 - 0.025 13.8 1.2 0.044 13.1 0.9 1.4 1 0 0 1 1 1 0 Transglycosylase Ded_cyto PF06920.8 EME78045.1 - 0.11 11.7 0.2 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Dedicator of cytokinesis Acetyltransf_2 PF00797.12 EME78046.1 - 1.5e-29 103.3 0.1 7.1e-29 101.0 0.1 2.1 1 1 0 1 1 1 1 N-acetyltransferase DUF2249 PF10006.4 EME78046.1 - 0.051 13.1 0.0 0.22 11.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) HET PF06985.6 EME78047.1 - 3.5e-31 108.2 0.1 5.1e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1835 PF08874.5 EME78047.1 - 0.011 15.6 0.1 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) adh_short PF00106.20 EME78050.1 - 9.3e-20 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME78050.1 - 1.9e-12 47.2 0.0 2.4e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME78050.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME78050.1 - 0.00028 20.7 0.0 0.00032 20.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME78050.1 - 0.0051 16.8 0.1 0.019 14.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding DUF4317 PF14199.1 EME78051.1 - 0.15 10.8 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) PCI_Csn8 PF10075.4 EME78052.1 - 9.5e-36 122.7 0.0 1.3e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EME78052.1 - 7.2e-25 87.7 0.1 1e-24 87.2 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EME78053.1 - 4.3e-56 189.0 0.0 1.7e-53 180.5 0.0 2.5 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain DUF3113 PF11310.3 EME78053.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Methyltransf_11 PF08241.7 EME78054.1 - 5e-11 42.9 0.0 8.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME78054.1 - 1.5e-10 41.6 0.0 2.8e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME78054.1 - 3.6e-10 40.1 0.0 5.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME78054.1 - 2.5e-09 37.0 0.0 4.2e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME78054.1 - 3.8e-08 33.6 0.0 5.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME78054.1 - 3.1e-07 30.0 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME78054.1 - 9e-07 28.9 0.1 2.3e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EME78054.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EME78054.1 - 4.9e-05 22.5 0.0 6.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EME78054.1 - 0.00084 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 EME78054.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 EME78054.1 - 0.0069 15.4 0.0 0.0079 15.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EME78054.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EME78054.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Fungal_trans_2 PF11951.3 EME78056.1 - 2.1e-05 23.3 0.2 2.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 EME78057.1 - 1.1e-96 324.0 46.4 1.4e-96 323.7 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME78057.1 - 9.8e-28 96.8 46.9 1.8e-27 95.9 32.5 1.4 1 1 0 1 1 1 1 Amino acid permease RdRP PF05183.7 EME78058.1 - 3.1e-129 432.3 0.0 1.4e-128 430.1 0.0 1.8 2 0 0 2 2 2 1 RNA dependent RNA polymerase AAA_12 PF13087.1 EME78058.1 - 9.8e-45 152.3 0.0 2e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME78058.1 - 5.7e-42 143.9 0.5 4.4e-40 137.7 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME78058.1 - 1.9e-11 43.9 0.5 7.1e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME78058.1 - 3.7e-11 42.6 0.0 4e-10 39.2 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain Helicase_RecD PF05127.9 EME78058.1 - 7.8e-06 25.6 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 EME78058.1 - 2.7e-05 23.5 0.1 0.00014 21.1 0.0 2.1 2 1 0 2 2 2 1 PhoH-like protein ResIII PF04851.10 EME78058.1 - 0.00029 20.7 0.0 0.00078 19.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EME78058.1 - 0.0012 18.2 2.0 0.011 15.0 0.0 2.7 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EME78058.1 - 0.0015 18.0 0.0 0.0048 16.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EME78058.1 - 0.0025 17.9 0.0 0.0061 16.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 EME78058.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME78058.1 - 0.0038 17.3 1.3 0.016 15.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EME78058.1 - 0.011 14.9 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 EME78058.1 - 0.077 12.6 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein zf-RING_2 PF13639.1 EME78059.1 - 4e-09 36.1 6.2 6.3e-09 35.5 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME78059.1 - 3e-07 30.3 5.6 4.5e-07 29.7 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME78059.1 - 3.7e-07 29.6 5.3 5.5e-07 29.1 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME78059.1 - 2.7e-06 26.9 3.2 3.7e-06 26.4 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME78059.1 - 0.00083 19.4 4.0 0.0016 18.5 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EME78059.1 - 0.0044 16.7 3.6 0.0071 16.0 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME78059.1 - 0.12 12.2 0.3 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EME78059.1 - 5.9 6.8 6.2 9.6 6.1 4.3 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HIT PF01230.18 EME78060.1 - 4.2e-24 84.9 0.1 5.6e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EME78060.1 - 5.9e-16 58.7 0.0 8.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EME78060.1 - 7.8e-06 25.5 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 YesK PF14150.1 EME78064.1 - 0.062 13.4 1.0 0.13 12.3 0.7 1.5 1 0 0 1 1 1 0 YesK-like protein Myosin_HC-like PF07058.6 EME78064.1 - 8.8 5.2 7.0 12 4.8 4.9 1.1 1 0 0 1 1 1 0 Myosin II heavy chain-like F-box-like_2 PF13013.1 EME78065.1 - 0.071 12.8 0.1 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain CDC45 PF02724.9 EME78065.1 - 1.3 6.9 8.6 2 6.3 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein YTH PF04146.10 EME78067.1 - 2e-45 153.8 0.0 3e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 EME78067.1 - 1.6e-08 34.3 0.0 4.3e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME78067.1 - 5.4e-08 32.3 0.0 1.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78067.1 - 0.00031 20.5 0.1 0.0007 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDKN3 PF05706.7 EME78067.1 - 0.033 13.6 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Fungal_trans PF04082.13 EME78069.1 - 1e-13 50.7 4.9 4.9e-08 32.1 0.1 2.7 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78069.1 - 3e-07 30.2 10.6 3e-07 30.2 7.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 EME78069.1 - 0.084 12.6 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 ThiF family TauD PF02668.11 EME78070.1 - 1.6e-25 90.2 0.0 2.1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EME78071.1 - 1.3e-33 116.2 26.4 1.7e-33 115.7 18.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.5 EME78071.1 - 0.014 15.3 2.5 0.63 9.9 0.2 3.4 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Abhydrolase_6 PF12697.2 EME78072.1 - 1.3e-36 126.6 0.0 1.7e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78072.1 - 1.6e-24 86.7 0.0 9.7e-23 80.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78072.1 - 2.5e-22 79.2 0.1 4.2e-22 78.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME78072.1 - 1e-09 37.9 0.0 0.00061 19.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 EME78072.1 - 9.7e-08 31.7 0.0 1.7e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.9 EME78072.1 - 1e-07 30.7 0.0 2.9e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.16 EME78072.1 - 1.2e-06 27.9 0.0 0.0022 17.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EME78072.1 - 3.9e-06 26.4 0.0 0.036 13.5 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EME78072.1 - 5.4e-06 26.2 0.0 1.2e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 EME78072.1 - 2.5e-05 24.1 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.8 EME78072.1 - 2.7e-05 23.8 0.0 0.0013 18.3 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.15 EME78072.1 - 0.00022 21.5 0.0 0.00025 21.3 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EME78072.1 - 0.00032 20.3 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EME78072.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EME78072.1 - 0.0015 17.0 0.0 0.068 11.6 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 EME78072.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.4 EME78072.1 - 0.0023 17.1 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase DUF2305 PF10230.4 EME78072.1 - 0.0028 17.1 0.0 0.018 14.4 0.0 2.0 1 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DUF676 PF05057.9 EME78072.1 - 0.0036 16.6 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF1057 PF06342.7 EME78072.1 - 0.0081 14.9 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.2 EME78072.1 - 0.044 12.6 0.1 0.069 12.0 0.1 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF2048 PF09752.4 EME78072.1 - 0.048 12.5 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF2974 PF11187.3 EME78072.1 - 0.055 12.8 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.6 EME78072.1 - 0.062 12.3 0.0 0.75 8.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAF-AH_p_II PF03403.8 EME78072.1 - 0.073 11.3 0.0 7.9 4.6 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PhoPQ_related PF10142.4 EME78072.1 - 0.1 11.0 0.0 0.22 9.9 0.0 1.6 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Tannase PF07519.6 EME78072.1 - 0.18 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Rab5-bind PF09311.6 EME78073.1 - 0.00023 21.0 16.4 0.00039 20.3 6.5 2.4 2 1 0 2 2 2 1 Rabaptin-like protein TBPIP PF07106.8 EME78073.1 - 0.00027 20.5 14.8 0.22 11.0 0.2 3.3 2 1 2 4 4 4 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Reo_sigmaC PF04582.7 EME78073.1 - 0.06 12.5 6.2 0.055 12.6 3.1 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1949 PF09186.6 EME78073.1 - 0.14 11.8 1.4 1 9.0 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1949) TMF_TATA_bd PF12325.3 EME78073.1 - 0.23 11.1 14.8 0.036 13.7 1.3 3.4 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EME78073.1 - 0.53 10.1 14.6 0.66 9.8 0.2 3.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.8 EME78073.1 - 0.67 9.6 8.6 0.18 11.4 2.5 2.6 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF2383 PF09537.5 EME78073.1 - 0.72 10.1 8.8 0.61 10.3 0.1 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF2383) TPR_MLP1_2 PF07926.7 EME78073.1 - 1.5 8.5 21.7 13 5.4 9.8 3.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin PF00804.20 EME78073.1 - 1.7 8.8 13.5 1.1 9.4 2.5 3.2 2 1 1 3 3 3 0 Syntaxin Sec20 PF03908.8 EME78073.1 - 3.7 7.3 7.0 25 4.6 0.2 3.2 2 1 1 3 3 3 0 Sec20 APG6 PF04111.7 EME78073.1 - 4.3 6.2 17.1 0.82 8.6 6.0 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Nup54 PF13874.1 EME78073.1 - 4.4 6.9 12.4 0.14 11.8 0.4 2.9 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 DUF948 PF06103.6 EME78073.1 - 4.5 7.2 7.6 24 4.8 0.5 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EME78073.1 - 4.8 7.2 10.7 2.6 8.1 1.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EME78073.1 - 9.8 5.7 17.5 0.15 11.5 0.6 4.0 3 1 1 4 4 4 0 Septum formation initiator TPR_11 PF13414.1 EME78074.1 - 3.2e-42 142.0 44.7 2.7e-08 33.3 0.0 14.1 11 5 4 15 15 15 8 TPR repeat TPR_1 PF00515.23 EME78074.1 - 2.8e-34 115.3 12.8 0.00016 21.1 0.0 13.2 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 EME78074.1 - 8e-34 115.8 21.7 4.3e-07 30.1 3.7 12.0 10 2 1 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 EME78074.1 - 5.7e-33 110.1 40.5 0.0065 16.3 0.0 16.7 18 0 0 18 18 16 8 Tetratricopeptide repeat TPR_16 PF13432.1 EME78074.1 - 1.1e-32 112.0 53.8 7.4e-08 32.8 6.3 13.8 11 2 2 13 13 13 7 Tetratricopeptide repeat TPR_17 PF13431.1 EME78074.1 - 5.5e-30 101.0 17.9 0.0074 16.4 0.0 15.9 17 0 0 17 17 17 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME78074.1 - 5e-26 88.8 50.6 0.0011 19.3 1.4 17.4 13 4 5 18 18 16 7 Tetratricopeptide repeat TPR_12 PF13424.1 EME78074.1 - 2.1e-19 69.2 46.0 0.0051 16.7 0.0 13.4 10 5 2 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.1 EME78074.1 - 2.2e-19 67.6 17.5 0.04 13.7 0.0 11.3 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EME78074.1 - 4.3e-15 54.2 25.7 0.0044 16.7 0.0 13.7 16 0 0 16 16 15 4 Tetratricopeptide repeat Apc3 PF12895.2 EME78074.1 - 1.5e-08 34.6 29.4 0.00014 21.9 2.1 7.1 9 2 1 10 10 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EME78074.1 - 4.3e-08 33.0 32.4 0.062 13.7 0.0 13.3 16 0 0 16 16 13 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME78074.1 - 6.8e-07 29.0 21.0 0.23 11.3 0.9 8.3 10 1 1 11 11 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 EME78074.1 - 3.3e-06 26.8 14.3 0.37 10.7 0.1 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 EME78074.1 - 2.6e-05 24.2 27.0 0.26 11.4 1.9 9.0 9 3 1 11 11 10 3 Tetratricopeptide repeat DUF2225 PF09986.4 EME78074.1 - 0.0037 16.7 4.9 1.1 8.6 0.1 3.7 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.1 EME78074.1 - 0.0069 16.2 12.4 40 4.2 0.0 7.9 9 1 1 10 10 10 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 EME78074.1 - 0.018 14.9 24.9 0.01 15.7 5.2 5.5 5 1 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EME78074.1 - 0.042 12.6 3.8 9.3 4.8 0.0 4.8 5 1 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 EME78074.1 - 0.15 12.6 24.5 0.33 11.4 0.0 10.0 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_3 PF07720.7 EME78074.1 - 2.1 8.2 16.4 2 8.2 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.7 EME78074.1 - 4.9 7.9 14.4 4.8 7.9 0.3 5.0 4 0 0 4 4 3 0 Sel1 repeat Microtub_assoc PF07989.6 EME78075.1 - 3.7e-18 65.1 6.2 3.7e-18 65.1 4.3 8.8 10 1 0 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 EME78075.1 - 5.8e-17 61.5 18.9 5.8e-17 61.5 13.1 10.2 9 3 2 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region SlyX PF04102.7 EME78075.1 - 0.0071 16.6 3.5 0.0071 16.6 2.4 10.8 9 3 2 12 12 12 3 SlyX Peroxidase_2 PF01328.12 EME78078.1 - 7.1e-27 93.8 0.0 8.6e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 COesterase PF00135.23 EME78079.1 - 1.7e-100 337.2 0.0 2.1e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME78079.1 - 0.012 15.1 0.6 0.091 12.3 0.4 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold RVT_3 PF13456.1 EME78080.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like zf-MYND PF01753.13 EME78082.1 - 2.9e-09 36.6 11.1 5.1e-09 35.8 7.7 1.4 1 0 0 1 1 1 1 MYND finger Proteasome PF00227.21 EME78083.1 - 1.2e-44 151.8 0.0 1.6e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EME78083.1 - 1.6e-14 52.8 1.9 3.9e-14 51.6 1.3 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Gemini_AL1 PF00799.15 EME78084.1 - 0.092 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain F-box-like PF12937.2 EME78085.1 - 3.9e-08 32.9 0.1 3.9e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME78085.1 - 7.9e-05 22.1 2.4 0.00022 20.8 0.0 2.5 2 0 0 2 2 2 1 F-box domain MIT PF04212.13 EME78085.1 - 0.065 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EME78087.1 - 1.1e-59 198.1 0.3 1.6e-18 66.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_11 PF08241.7 EME78088.1 - 1.4e-17 63.9 0.0 2.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME78088.1 - 3.5e-14 52.6 0.0 4.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME78088.1 - 9.9e-14 51.3 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME78088.1 - 1.4e-11 44.0 0.0 1.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EME78088.1 - 5.7e-11 41.9 0.0 8.9e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME78088.1 - 1e-08 35.5 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME78088.1 - 2.1e-08 34.4 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME78088.1 - 3.8e-08 33.8 0.0 7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME78088.1 - 3.2e-05 23.9 0.0 0.00023 21.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Sterol_MT_C PF08498.5 EME78088.1 - 8.7e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal MTS PF05175.9 EME78088.1 - 0.032 13.6 0.0 0.072 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.5 EME78088.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Acetyltransf_1 PF00583.19 EME78090.1 - 2e-11 43.7 0.1 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME78090.1 - 7.7e-07 29.2 0.0 9.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME78090.1 - 0.00019 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CRAL_TRIO PF00650.15 EME78091.1 - 2.6e-35 121.2 0.0 6.7e-35 119.9 0.0 1.7 3 0 0 3 3 3 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME78091.1 - 4.4e-09 36.3 0.1 1.1e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EME78091.1 - 3.2e-05 23.8 0.0 9.6e-05 22.3 0.0 1.8 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain F-box PF00646.28 EME78092.1 - 4e-06 26.3 0.1 1.3e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME78092.1 - 0.00035 20.2 1.7 0.00046 19.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like Vps51 PF08700.6 EME78095.1 - 4.8e-30 103.2 0.0 1.4e-29 101.7 0.0 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EME78095.1 - 0.00049 18.6 0.1 0.00065 18.2 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 EME78095.1 - 0.0006 19.6 0.0 0.0031 17.2 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec5 COG5 PF10392.4 EME78095.1 - 0.0043 17.0 0.1 0.017 15.0 0.0 2.0 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Laminin_I PF06008.9 EME78095.1 - 0.04 13.2 0.3 0.057 12.7 0.2 1.3 1 0 0 1 1 1 0 Laminin Domain I DUF1767 PF08585.7 EME78096.1 - 1.2e-12 47.9 0.1 2.3e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) HATPase_c PF02518.21 EME78098.1 - 1e-22 79.9 0.0 2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME78098.1 - 1.1e-20 73.6 0.4 2.6e-20 72.5 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.1 EME78098.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase N6-adenineMlase PF10237.4 EME78098.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DUF3767 PF12597.3 EME78102.1 - 4e-27 94.2 0.1 4.3e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF4547 PF15080.1 EME78102.1 - 0.018 14.4 0.2 0.026 13.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) DUF1744 PF08490.7 EME78103.1 - 1.7e-139 464.8 0.0 3.2e-139 463.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EME78103.1 - 2.1e-66 224.0 0.1 4.2e-66 223.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EME78103.1 - 1.9e-23 82.9 0.1 5.7e-23 81.4 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EME78103.1 - 9.5e-12 44.8 0.0 2.4e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EME78103.1 - 2.6e-05 24.1 0.0 0.0001 22.1 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily p450 PF00067.17 EME78104.1 - 5.8e-25 87.7 0.0 8e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.9 EME78105.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Pyr_redox_3 PF13738.1 EME78106.1 - 4.1e-25 89.0 0.0 2.2e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME78106.1 - 4.9e-21 74.5 0.0 3.4e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME78106.1 - 2.1e-11 44.0 0.0 1.4e-07 31.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME78106.1 - 7.5e-11 41.5 0.1 1.8e-08 33.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME78106.1 - 8.2e-11 41.7 0.0 3.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME78106.1 - 1.2e-07 31.6 0.1 0.015 15.0 0.1 4.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EME78106.1 - 2.6e-05 24.5 0.1 0.27 11.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME78106.1 - 0.00017 20.6 0.0 0.034 13.0 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME78106.1 - 0.00036 19.6 0.0 0.0011 18.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EME78106.1 - 0.00076 18.4 0.0 1.5 7.6 0.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EME78106.1 - 0.0019 17.1 0.0 0.0033 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EME78106.1 - 0.0099 15.9 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EME78106.1 - 0.03 12.7 0.1 0.33 9.3 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 EME78106.1 - 0.082 11.8 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EME78106.1 - 0.13 11.2 0.2 1.8 7.5 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Kelch_4 PF13418.1 EME78107.1 - 5.3e-17 61.3 0.5 0.00038 20.1 0.0 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EME78107.1 - 2.8e-14 52.7 1.2 0.0064 16.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EME78107.1 - 7.1e-13 48.3 9.6 0.0092 16.1 0.0 7.6 7 1 1 8 8 8 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EME78107.1 - 2.4e-10 39.8 0.1 0.0046 16.4 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EME78107.1 - 8.8e-10 38.3 1.3 0.022 14.9 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EME78107.1 - 4.6e-09 35.6 2.6 1.1 9.1 0.0 7.0 6 1 1 7 7 7 2 Kelch motif TauD PF02668.11 EME78109.1 - 3.1e-27 95.8 0.0 4e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 EME78110.1 - 3.2e-09 36.5 8.7 6.8e-09 35.4 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_72 PF03198.9 EME78113.1 - 1e-132 441.9 8.1 1.4e-132 441.4 5.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EME78113.1 - 3.4e-25 88.3 5.3 9.5e-25 86.9 3.7 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EME78113.1 - 8.7e-05 21.5 0.2 0.00016 20.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glucan_synthase PF02364.10 EME78114.1 - 0 1461.7 0.0 0 1461.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EME78114.1 - 3.4e-36 123.7 0.8 8.6e-36 122.3 0.6 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF4106 PF13388.1 EME78115.1 - 0.23 10.3 0.1 0.34 9.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) AMP-binding PF00501.23 EME78116.1 - 5e-72 242.5 0.0 8e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME78116.1 - 2.5e-11 44.3 0.1 5.7e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.19 EME78116.1 - 1.1e-07 30.9 18.0 2.4e-05 23.6 1.0 6.2 4 2 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 EME78116.1 - 1.1e-05 25.5 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 EME78116.1 - 0.0015 18.0 16.3 0.0083 15.6 0.7 4.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mito_carr PF00153.22 EME78119.1 - 1.7e-58 194.2 3.5 4.1e-23 80.8 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein MAM33 PF02330.11 EME78120.1 - 3.6e-22 79.1 1.2 7.5e-18 65.0 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein Fork_head PF00250.13 EME78123.1 - 0.049 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Fork head domain Sugar_tr PF00083.19 EME78125.1 - 1.7e-71 241.1 16.6 4.2e-70 236.5 9.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME78125.1 - 9e-18 64.1 11.5 9e-18 64.1 8.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sua5_yciO_yrdC PF01300.13 EME78127.1 - 3.6e-10 39.3 0.0 8.8e-10 38.1 0.0 1.7 1 1 0 1 1 1 1 Telomere recombination FMO-like PF00743.14 EME78128.1 - 6.4e-23 80.7 0.0 5.4e-13 47.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME78128.1 - 2.4e-16 60.4 0.0 1.1e-15 58.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME78128.1 - 1.2e-07 31.6 0.1 1.8e-06 27.8 0.1 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME78128.1 - 1.6e-06 28.0 0.0 3.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME78128.1 - 4.1e-06 26.8 0.0 0.75 9.6 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME78128.1 - 9.9e-06 24.6 0.4 0.011 14.7 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EME78128.1 - 0.0012 17.9 0.0 0.053 12.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EME78128.1 - 0.0018 17.2 0.1 0.15 10.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME78128.1 - 0.085 11.3 0.0 0.23 9.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EME78128.1 - 0.14 12.5 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Transp_Tc5_C PF04236.10 EME78129.1 - 0.27 11.4 1.7 2.4 8.4 0.4 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HATPase_c PF02518.21 EME78130.1 - 9.5e-21 73.6 0.0 7.5e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME78130.1 - 1.4e-19 70.1 0.0 3.7e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EME78130.1 - 1.1e-12 47.7 0.0 5e-12 45.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 EME78130.1 - 0.038 13.7 0.0 0.49 10.1 0.0 2.7 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain SMC_N PF02463.14 EME78132.1 - 2e-26 92.5 0.1 3.3e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME78132.1 - 9e-08 32.6 27.5 9e-08 32.6 19.1 4.8 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EME78132.1 - 2e-06 27.9 6.5 0.0011 19.0 0.8 3.5 3 2 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EME78132.1 - 0.00056 19.7 0.0 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EME78132.1 - 0.0015 18.0 0.2 0.0068 15.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EME78132.1 - 0.0021 17.1 6.5 0.0021 17.1 4.5 2.7 3 1 0 3 3 3 1 AAA ATPase domain Esterase PF00756.15 EME78133.1 - 4e-11 42.8 0.0 1.1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EME78133.1 - 0.093 11.9 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Flu_C_NS2 PF03555.9 EME78134.1 - 0.066 13.1 0.2 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) His_Phos_1 PF00300.17 EME78136.1 - 1.3e-38 132.5 0.0 2e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PROL5-SMR PF15621.1 EME78137.1 - 7.7 6.9 11.7 0.97 9.8 2.9 2.1 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Glyco_hydro_18 PF00704.23 EME78139.1 - 5.5e-12 45.7 0.0 7.2e-11 42.1 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Oxidored_molyb PF00174.14 EME78140.1 - 2e-48 164.0 0.0 3.2e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EME78140.1 - 1.9e-34 118.1 0.1 3.8e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EME78140.1 - 4e-13 48.9 0.0 7.7e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Methyltransf_15 PF09445.5 EME78141.1 - 6.5e-49 165.6 0.0 8.2e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EME78141.1 - 1.3e-08 34.6 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EME78141.1 - 4.4e-08 33.1 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME78141.1 - 2e-07 30.8 0.0 2.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EME78141.1 - 6e-06 25.7 0.0 9.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EME78141.1 - 1.7e-05 25.3 0.0 2.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME78141.1 - 0.00066 19.2 0.0 0.0014 18.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EME78141.1 - 0.026 13.5 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EME78141.1 - 0.044 12.8 0.1 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DNA_methylase PF00145.12 EME78141.1 - 0.047 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase CAF1 PF04857.15 EME78141.1 - 0.089 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease Methyltransf_5 PF01795.14 EME78141.1 - 0.092 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family MTS PF05175.9 EME78141.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EME78141.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF367 PF04034.8 EME78142.1 - 2.6e-49 166.0 0.0 3.8e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EME78142.1 - 2.5e-09 36.5 0.1 4.2e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI ATP-grasp_4 PF13535.1 EME78144.1 - 1.2e-08 34.9 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME78144.1 - 0.0029 16.3 0.0 0.011 14.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon DHQ_synthase PF01761.15 EME78145.1 - 4.3e-53 179.8 0.0 6.1e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EME78145.1 - 3.2e-12 46.3 0.0 4.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DXP_synthase_N PF13292.1 EME78147.1 - 0.045 12.6 0.1 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DnaJ PF00226.26 EME78148.1 - 5e-26 90.2 0.4 5e-26 90.2 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EME78148.1 - 7.1e-11 41.9 3.4 7.1e-11 41.9 2.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME78148.1 - 2.8e-08 33.6 2.0 2.8e-08 33.6 1.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EME78148.1 - 0.00024 21.1 7.5 0.0073 16.3 2.5 3.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EME78148.1 - 0.0064 16.2 1.8 0.016 14.9 1.2 1.7 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EME78148.1 - 0.0073 16.5 3.5 1.3 9.5 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME78148.1 - 0.08 13.3 7.5 3.1 8.3 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME78148.1 - 0.12 12.7 1.2 16 6.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DUF2828 PF11443.3 EME78149.1 - 1.3e-66 224.9 0.2 1.7e-66 224.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF3317 PF11779.3 EME78150.1 - 1e-13 50.5 1.3 1.4e-13 49.9 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) PIR PF00399.14 EME78151.1 - 5.9e-17 60.3 32.2 1.8e-06 27.0 2.5 3.7 3 0 0 3 3 3 3 Yeast PIR protein repeat Prenylcys_lyase PF07156.9 EME78153.1 - 1.2e-32 113.2 0.0 6.6e-32 110.8 0.0 2.0 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EME78153.1 - 2.9e-11 43.2 0.1 8.8e-11 41.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME78153.1 - 1.7e-09 37.2 0.0 9e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EME78153.1 - 3.7e-05 22.7 0.2 0.00049 19.0 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME78153.1 - 9.6e-05 22.2 0.1 0.00065 19.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME78153.1 - 0.00011 22.3 0.0 0.0051 16.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EME78153.1 - 0.0037 16.7 0.1 0.19 11.1 0.0 3.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EME78153.1 - 0.0046 16.5 0.2 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EME78153.1 - 0.0046 17.0 0.2 0.049 13.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EME78153.1 - 0.0051 15.7 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EME78153.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EME78153.1 - 0.014 15.7 1.0 3.2 8.2 0.0 3.4 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME78153.1 - 0.016 15.0 0.1 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME78153.1 - 0.04 12.7 0.2 0.089 11.6 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A bZIP_1 PF00170.16 EME78154.1 - 0.0004 20.2 8.3 0.0019 18.1 5.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME78154.1 - 0.01 15.6 2.6 0.01 15.6 1.8 2.0 1 1 1 2 2 2 0 Basic region leucine zipper ADSL_C PF10397.4 EME78154.1 - 0.045 13.7 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus CDC45 PF02724.9 EME78154.1 - 0.11 10.4 1.0 0.12 10.4 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein OSTbeta PF15048.1 EME78154.1 - 0.13 12.2 1.6 0.13 12.3 1.1 1.0 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein HeH PF12949.2 EME78154.1 - 0.14 11.7 1.1 1.4 8.5 0.1 2.3 2 1 0 2 2 2 0 HeH/LEM domain IncA PF04156.9 EME78154.1 - 0.36 10.4 3.3 0.4 10.2 2.3 1.0 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 EME78154.1 - 0.4 10.2 2.7 0.48 9.9 1.9 1.2 1 1 0 1 1 1 0 GrpE CENP-Q PF13094.1 EME78154.1 - 0.85 9.6 4.7 1.4 8.9 3.3 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF221 PF02714.10 EME78155.1 - 1.9e-94 316.1 16.3 1.9e-94 316.1 11.3 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME78155.1 - 5.9e-42 142.8 5.8 5.9e-42 142.8 4.0 2.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EME78155.1 - 6.4e-20 70.8 0.0 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EME78155.1 - 3.7e-13 49.7 3.5 8.2e-13 48.6 2.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Peptidase_M50 PF02163.17 EME78155.1 - 0.036 13.0 0.0 0.21 10.5 0.0 2.2 2 1 0 2 2 2 0 Peptidase family M50 RRM_1 PF00076.17 EME78155.1 - 0.15 11.7 0.1 0.46 10.1 0.1 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_A_type_inc PF04508.7 EME78155.1 - 0.29 11.0 1.1 0.59 10.0 0.7 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat F-box-like PF12937.2 EME78156.1 - 0.006 16.2 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME78156.1 - 0.052 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain UPF0203 PF05254.7 EME78157.1 - 1.2e-29 101.9 1.7 1.4e-29 101.7 1.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EME78157.1 - 0.00054 19.9 0.9 0.0016 18.3 0.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EME78157.1 - 0.003 17.2 4.6 0.12 12.1 0.2 2.4 1 1 2 3 3 3 3 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EME78157.1 - 0.14 12.0 2.7 2.9 7.9 0.2 2.2 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Cpn60_TCP1 PF00118.19 EME78158.1 - 7.5e-143 476.6 3.1 8.8e-143 476.4 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prefoldin_2 PF01920.15 EME78161.1 - 2.4e-23 81.9 15.7 3.1e-23 81.5 10.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EME78161.1 - 1.9e-05 24.2 10.7 0.00038 20.0 1.6 2.3 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin_3 PF13758.1 EME78161.1 - 0.00062 19.5 5.0 0.00062 19.5 3.5 1.6 1 1 1 2 2 2 1 Prefoldin subunit IncA PF04156.9 EME78161.1 - 0.0017 17.9 15.6 0.0051 16.4 10.8 1.6 1 1 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 EME78161.1 - 0.0046 16.8 12.9 0.14 12.0 1.6 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EME78161.1 - 0.0053 16.4 13.1 0.035 13.8 1.8 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 Spc7 PF08317.6 EME78161.1 - 0.0065 15.1 12.8 0.0077 14.9 8.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Hpt PF01627.18 EME78161.1 - 0.0084 16.0 1.1 0.047 13.7 0.2 2.1 2 0 0 2 2 2 1 Hpt domain DASH_Dad3 PF08656.5 EME78161.1 - 0.049 13.3 7.9 0.11 12.2 1.2 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad3 Sugarporin_N PF11471.3 EME78161.1 - 0.055 13.1 0.1 0.055 13.1 0.1 2.8 1 1 1 2 2 1 0 Maltoporin periplasmic N-terminal extension NPV_P10 PF05531.7 EME78161.1 - 0.072 13.3 12.2 0.89 9.8 2.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mto2_bdg PF12808.2 EME78161.1 - 0.082 13.0 2.3 1.5 8.9 0.3 2.4 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region BLOC1_2 PF10046.4 EME78161.1 - 0.09 12.9 10.0 1.3 9.1 1.2 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ERp29 PF07749.7 EME78161.1 - 0.11 13.1 4.2 0.19 12.4 2.9 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain PAD PF03068.10 EME78161.1 - 0.12 10.7 0.8 0.14 10.5 0.6 1.0 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Sas10_Utp3 PF04000.10 EME78161.1 - 0.17 12.0 7.1 0.88 9.8 1.2 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Tropomyosin_1 PF12718.2 EME78161.1 - 0.23 11.3 15.1 1.4 8.7 9.4 2.0 1 1 0 1 1 1 0 Tropomyosin like CCDC155 PF14662.1 EME78161.1 - 0.23 11.0 14.3 0.71 9.4 9.9 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF724 PF05266.9 EME78161.1 - 0.24 10.9 10.8 0.41 10.2 7.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) IFT46_B_C PF12317.3 EME78161.1 - 0.25 10.7 4.1 0.17 11.2 1.7 1.4 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DASH_Dam1 PF08653.5 EME78161.1 - 0.27 11.0 2.3 0.79 9.5 0.2 2.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF4140 PF13600.1 EME78161.1 - 0.31 11.4 10.1 1.8 9.0 0.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 EME78161.1 - 0.39 10.5 15.2 0.13 12.1 2.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EME78161.1 - 0.42 9.7 14.3 0.43 9.7 3.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GP41 PF00517.12 EME78161.1 - 0.45 10.0 9.6 1.5 8.3 1.3 2.0 2 0 0 2 2 2 0 Retroviral envelope protein Tropomyosin PF00261.15 EME78161.1 - 0.49 9.4 11.4 8.1 5.4 7.9 2.0 1 1 0 1 1 1 0 Tropomyosin Occludin_ELL PF07303.8 EME78161.1 - 0.63 10.8 9.9 0.8 10.4 1.7 2.1 2 0 0 2 2 2 0 Occludin homology domain MIP-T3 PF10243.4 EME78161.1 - 0.67 8.3 13.4 0.024 13.1 4.7 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 EME78161.1 - 0.68 8.1 12.6 1.1 7.4 8.7 1.3 1 1 0 1 1 1 0 Transmembrane protein TcdA_TcdB PF12919.2 EME78161.1 - 0.92 7.9 7.9 1.1 7.6 5.4 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Osmo_CC PF08946.5 EME78161.1 - 0.95 9.5 8.0 0.42 10.6 1.8 2.7 2 2 0 2 2 2 0 Osmosensory transporter coiled coil DivIC PF04977.10 EME78161.1 - 1.1 8.8 16.6 0.062 12.7 1.7 3.1 1 1 3 4 4 4 0 Septum formation initiator EAP30 PF04157.11 EME78161.1 - 1.1 8.3 12.3 0.47 9.5 1.6 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family COG2 PF06148.6 EME78161.1 - 1.2 9.0 8.4 2.6 7.9 0.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 EME78161.1 - 1.2 9.4 10.4 6.6 7.1 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EME78161.1 - 1.2 8.0 14.4 8.7 5.2 9.9 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 EME78161.1 - 1.3 8.9 25.4 1.4 8.9 7.3 2.2 2 0 0 2 2 2 0 FlxA-like protein TMPIT PF07851.8 EME78161.1 - 1.3 7.9 8.5 1.6 7.7 5.1 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.1 EME78161.1 - 1.5 8.7 14.1 2.2 8.2 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Cep57_CLD_2 PF14197.1 EME78161.1 - 1.7 8.6 6.4 0.69 9.9 1.3 2.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Kinetocho_Slk19 PF12709.2 EME78161.1 - 1.8 8.7 12.2 12 6.0 0.8 3.2 2 2 1 3 3 3 0 Central kinetochore-associated DUF1664 PF07889.7 EME78161.1 - 1.8 8.3 12.2 3.7 7.3 2.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) YgaB PF14182.1 EME78161.1 - 2 8.6 14.7 1.2 9.3 2.8 2.4 2 1 0 2 2 2 0 YgaB-like protein AAA_13 PF13166.1 EME78161.1 - 2.6 6.4 14.1 9.4 4.5 9.8 1.7 1 1 0 1 1 1 0 AAA domain DUF3571 PF12095.3 EME78161.1 - 2.7 8.2 5.3 13 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) Spectrin PF00435.16 EME78161.1 - 2.9 8.2 13.2 4.8 7.5 1.8 2.2 1 1 0 2 2 2 0 Spectrin repeat DUF3847 PF12958.2 EME78161.1 - 2.9 7.6 11.0 6.1 6.6 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Lzipper-MIP1 PF14389.1 EME78161.1 - 3 7.9 11.6 0.77 9.9 1.9 2.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF2408 PF10303.4 EME78161.1 - 3.2 7.8 9.4 24 5.0 6.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF3375 PF11855.3 EME78161.1 - 3.2 6.3 8.5 0.23 10.1 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Fib_alpha PF08702.5 EME78161.1 - 3.4 7.8 13.4 11 6.0 9.3 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EME78161.1 - 3.4 7.4 17.3 3.1 7.5 7.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FliD_C PF07195.7 EME78161.1 - 3.5 6.8 11.5 16 4.6 7.9 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF607 PF04678.8 EME78161.1 - 3.7 7.4 5.4 36 4.2 3.8 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF607 SPX PF03105.14 EME78161.1 - 3.8 7.1 8.1 15 5.2 5.6 1.8 1 1 0 1 1 1 0 SPX domain DegS PF05384.6 EME78161.1 - 3.9 6.6 11.2 6.8 5.8 2.4 2.2 2 0 0 2 2 2 0 Sensor protein DegS DUF641 PF04859.7 EME78161.1 - 4.8 6.9 11.8 4.2 7.1 2.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 EME78161.1 - 4.9 6.9 13.5 0.93 9.2 1.7 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Val_tRNA-synt_C PF10458.4 EME78161.1 - 6.8 6.8 11.1 2.9 8.0 0.2 3.3 3 1 1 4 4 4 0 Valyl tRNA synthetase tRNA binding arm FlaC_arch PF05377.6 EME78161.1 - 7 6.6 9.8 9.7 6.1 0.2 3.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Tho2 PF11262.3 EME78161.1 - 7 5.5 10.3 4.1 6.3 1.9 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Allexi_40kDa PF05549.6 EME78161.1 - 7.7 5.7 10.7 6.7 5.9 0.9 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein CHD5 PF04420.9 EME78161.1 - 8.3 6.0 9.1 2.2 7.9 1.1 2.3 2 1 0 2 2 2 0 CHD5-like protein V_ATPase_I PF01496.14 EME78161.1 - 8.5 4.0 11.0 25 2.5 1.0 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.24 EME78162.1 - 1.7e-42 144.7 0.0 3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EME78162.1 - 7.8e-30 102.5 0.1 2.7e-29 100.8 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EME78162.1 - 5.8e-22 77.3 8.0 1.7e-21 75.8 5.2 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EME78162.1 - 9.4e-07 29.6 0.2 8.7e-06 26.5 0.0 2.8 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EME78162.1 - 2.4e-06 26.7 0.0 4.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME78162.1 - 7.9e-06 26.0 0.1 0.00084 19.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME78162.1 - 1.3e-05 25.1 0.0 0.0042 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EME78162.1 - 1.9e-05 24.1 0.0 4.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EME78162.1 - 2.4e-05 24.0 0.0 0.00015 21.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EME78162.1 - 3.6e-05 23.6 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME78162.1 - 6.1e-05 23.1 0.0 0.0097 16.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EME78162.1 - 6.8e-05 22.9 0.0 0.0017 18.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EME78162.1 - 8.5e-05 21.4 0.0 0.00014 20.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EME78162.1 - 0.00012 21.5 0.1 0.19 11.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EME78162.1 - 0.00016 20.7 0.0 0.002 17.1 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EME78162.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EME78162.1 - 0.0058 16.2 0.3 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME78162.1 - 0.0061 16.8 0.3 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME78162.1 - 0.0071 15.4 0.1 0.14 11.2 0.0 2.7 2 1 1 3 3 3 1 Zeta toxin Mg_chelatase PF01078.16 EME78162.1 - 0.019 14.1 0.0 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EME78162.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EME78162.1 - 0.026 14.2 0.0 0.62 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 EME78162.1 - 0.027 14.3 0.0 0.072 12.9 0.0 1.7 2 0 0 2 2 1 0 Torsin ResIII PF04851.10 EME78162.1 - 0.029 14.2 0.1 0.073 12.8 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EME78162.1 - 0.029 14.0 0.9 0.2 11.3 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 EME78162.1 - 0.036 12.9 0.0 0.086 11.6 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 USP8_dimer PF08969.6 EME78162.1 - 0.037 14.0 4.2 0.083 12.8 2.9 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_21 PF13304.1 EME78162.1 - 0.048 13.6 0.4 3.1 7.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EME78162.1 - 0.048 12.8 0.5 0.094 11.9 0.0 1.7 2 0 0 2 2 1 0 PhoH-like protein Peptidase_M28 PF04389.12 EME78162.1 - 0.064 12.9 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 CPT PF07931.7 EME78162.1 - 0.087 12.4 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EME78162.1 - 0.14 11.2 0.0 7.2 5.6 0.0 2.3 1 1 1 2 2 2 0 KaiC TPR_1 PF00515.23 EME78162.1 - 0.21 11.2 6.2 0.35 10.5 2.8 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat KAP_NTPase PF07693.9 EME78162.1 - 0.31 9.9 1.6 14 4.5 0.0 2.8 2 1 0 2 2 2 0 KAP family P-loop domain CBS PF00571.23 EME78164.1 - 2.7e-39 132.6 11.0 4.9e-10 39.0 0.0 5.1 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 EME78164.1 - 4.2e-09 35.9 0.0 1.6e-08 34.1 0.0 2.0 2 1 0 2 2 2 1 PB1 domain DUF3235 PF11574.3 EME78164.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Ribosomal_S26e PF01283.14 EME78165.1 - 5.9e-51 171.5 9.0 6.9e-51 171.2 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EME78165.1 - 0.035 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 EME78165.1 - 0.053 13.8 0.2 7.4 6.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EME78165.1 - 0.087 13.2 1.4 1.7 9.0 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Cys_Met_Meta_PP PF01053.15 EME78167.1 - 2.2e-34 118.4 0.0 3e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EME78167.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Nrap PF03813.9 EME78168.1 - 0 1070.1 0.0 0 1069.8 0.0 1.0 1 0 0 1 1 1 1 Nrap protein OTU PF02338.14 EME78169.1 - 1.4e-11 45.0 0.0 2.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF2318 PF10080.4 EME78169.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) UN_NPL4 PF11543.3 EME78169.1 - 0.099 12.9 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 PB1 PF00564.19 EME78169.1 - 0.14 11.8 0.0 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 PB1 domain Bromodomain PF00439.20 EME78170.1 - 2.2e-36 123.6 8.8 7.7e-18 64.1 2.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EME78170.1 - 7.4e-15 54.7 0.2 7.4e-15 54.7 0.1 1.7 2 0 0 2 2 2 1 BAH domain Sigma70_ner PF04546.8 EME78170.1 - 8 6.0 23.4 0.017 14.7 2.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_ligase_A_M PF01068.16 EME78173.1 - 8.4e-49 165.6 0.1 5.4e-46 156.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EME78173.1 - 8.8e-44 149.4 0.0 1.6e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EME78173.1 - 7.4e-18 64.7 0.2 1.1e-16 60.9 0.0 2.8 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region HET PF06985.6 EME78174.1 - 3.1e-09 37.1 3.3 3.3e-09 37.0 2.3 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.3 EME78175.1 - 4.8e-21 75.4 6.1 5.5e-21 75.2 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TMEM213 PF15192.1 EME78175.1 - 0.0071 16.3 0.3 0.01 15.7 0.2 1.4 1 1 0 1 1 1 1 TMEM213 family PhzC-PhzF PF02567.11 EME78176.1 - 3.3e-07 29.8 3.3 7.8 5.6 0.0 7.0 1 1 7 8 8 8 2 Phenazine biosynthesis-like protein EDR1 PF14381.1 EME78176.1 - 0.0072 15.9 10.1 1.3 8.5 0.2 4.1 1 1 4 5 5 5 3 Ethylene-responsive protein kinase Le-CTR1 DltD_N PF04915.7 EME78176.1 - 0.059 13.2 25.0 39 4.2 0.2 8.9 1 1 7 8 8 8 0 DltD N-terminal region Phe_hydrox_dim PF07976.7 EME78176.1 - 0.42 10.2 13.3 5.6 6.5 0.2 4.2 1 1 4 5 5 5 0 Phenol hydroxylase, C-terminal dimerisation domain DUF3841 PF12952.2 EME78176.1 - 1.3 8.4 6.1 48 3.3 0.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3841) DUF3328 PF11807.3 EME78177.1 - 1e-29 103.8 1.6 1.1e-29 103.6 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Imm21 PF15569.1 EME78177.1 - 0.019 14.7 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 21 YceG PF02618.11 EME78177.1 - 0.099 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 YceG-like family AAA_12 PF13087.1 EME78178.1 - 1.4e-17 63.7 0.0 2.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME78178.1 - 7.4e-05 22.4 0.0 0.00022 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME78178.1 - 0.0028 17.3 0.0 0.0071 16.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NT5C PF06941.7 EME78178.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF1772 PF08592.6 EME78179.1 - 2e-10 40.5 4.9 3.4e-10 39.7 1.6 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) FeoB_C PF07664.7 EME78184.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus p450 PF00067.17 EME78185.1 - 1.1e-74 251.6 0.0 1.4e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPP_enzyme_N PF02776.13 EME78187.1 - 9.4e-41 139.1 0.0 2.5e-40 137.7 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME78187.1 - 7.2e-33 113.2 0.1 1.6e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EME78187.1 - 2.6e-20 72.5 1.7 6.8e-20 71.1 1.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EME78187.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AMP-binding PF00501.23 EME78188.1 - 8.4e-88 294.5 0.0 9.8e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME78188.1 - 1.6e-13 51.3 0.0 7.4e-13 49.2 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GMC_oxred_N PF00732.14 EME78191.1 - 3.9e-60 203.4 0.0 5.6e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME78191.1 - 6.7e-38 130.2 0.0 1.1e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME78191.1 - 0.0014 17.5 0.0 0.036 12.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EME78191.1 - 0.0067 15.3 0.7 0.14 11.0 0.6 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase COesterase PF00135.23 EME78193.1 - 5e-88 296.1 0.0 5.6e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME78193.1 - 4.1e-08 33.0 0.0 1.5e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78193.1 - 0.038 13.7 0.1 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 EME78194.1 - 1.1e-22 80.1 0.0 1.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME78194.1 - 1.1e-11 44.6 0.2 3.3e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ICEA PF05315.6 EME78195.1 - 0.028 13.7 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 ICEA Protein Glyco_hydro_3 PF00933.16 EME78196.1 - 6.5e-52 176.3 0.0 1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME78196.1 - 3.9e-44 150.8 0.0 5.3e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain PA14 PF07691.7 EME78196.1 - 6e-10 38.9 0.1 3e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 PA14 domain Fn3-like PF14310.1 EME78196.1 - 1.4e-09 37.7 0.4 3.7e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Sel1 PF08238.7 EME78197.1 - 1.8e-21 76.0 33.3 8.9e-08 32.5 0.0 7.4 7 0 0 7 7 7 6 Sel1 repeat TPR_1 PF00515.23 EME78197.1 - 9.7e-05 21.8 5.6 0.0043 16.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME78197.1 - 0.016 15.0 5.5 1.5 8.9 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME78197.1 - 0.031 14.2 1.4 0.91 9.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME78197.1 - 0.13 12.9 4.6 22 6.0 0.0 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat Fig1 PF12351.3 EME78198.1 - 1.7e-56 190.9 4.3 1.7e-56 190.9 3.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EME78198.1 - 2.1e-11 43.8 8.7 2.9e-11 43.3 6.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EME78198.1 - 0.0022 16.9 6.2 0.0022 16.9 4.3 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EME78198.1 - 0.14 12.3 0.3 0.14 12.3 0.2 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EME78198.1 - 0.34 11.1 6.2 0.2 11.8 1.4 2.8 2 0 0 2 2 2 0 MltD lipid attachment motif DUF4131 PF13567.1 EME78198.1 - 3.9 6.8 17.1 0.19 11.1 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HEAT_2 PF13646.1 EME78199.1 - 0.061 13.6 2.0 0.36 11.1 0.0 3.4 4 1 0 4 4 4 0 HEAT repeats DUF1423 PF07227.6 EME78200.1 - 0.44 9.1 2.2 0.78 8.3 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) p450 PF00067.17 EME78201.1 - 2.3e-54 184.6 0.0 3e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EME78202.1 - 2.7e-25 89.0 0.1 3.7e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Mito_carr PF00153.22 EME78204.1 - 5.4e-64 211.9 2.5 1.3e-21 76.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 EME78205.1 - 1.6e-70 233.4 25.0 1.5e-18 66.9 0.5 5.9 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EME78205.1 - 7.3e-62 202.2 26.6 1.3e-06 27.9 0.1 12.1 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 EME78205.1 - 4.2e-50 167.2 16.0 1.1e-09 38.5 0.0 8.5 6 1 3 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME78205.1 - 2.6e-46 150.9 16.1 1.1e-05 25.1 0.1 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EME78205.1 - 2.8e-46 154.4 25.4 5.1e-11 42.4 0.6 10.1 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Pyr_redox_3 PF13738.1 EME78206.1 - 1e-22 81.2 0.0 2.5e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME78206.1 - 1.5e-07 30.0 0.0 2.1e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME78206.1 - 3.4e-05 23.8 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME78206.1 - 0.00022 21.0 0.0 0.0019 18.0 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME78206.1 - 0.0019 18.1 0.0 0.0066 16.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME78206.1 - 0.0063 15.4 0.0 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EME78206.1 - 0.04 12.8 0.1 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EME78206.1 - 0.14 10.6 0.0 1.8 6.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EME78206.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HsbA PF12296.3 EME78207.1 - 6.9e-19 67.9 11.3 6.9e-19 67.9 7.8 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NPV_P10 PF05531.7 EME78207.1 - 0.012 15.7 0.7 0.012 15.7 0.5 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CoatB PF10389.4 EME78207.1 - 0.085 12.7 8.2 0.63 9.9 1.4 3.1 2 0 0 2 2 2 0 Bacteriophage coat protein B Rad52_Rad22 PF04098.10 EME78207.1 - 0.27 10.9 1.7 2.6 7.7 0.2 2.4 1 1 1 2 2 2 0 Rad52/22 family double-strand break repair protein HsbA PF12296.3 EME78208.1 - 5.8e-17 61.6 3.7 7.7e-17 61.3 2.5 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF515 PF04415.7 EME78208.1 - 0.0076 14.5 0.4 0.012 13.8 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF515) DUF2277 PF10041.4 EME78208.1 - 0.11 12.5 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) DUF2358 PF10184.4 EME78210.1 - 0.025 14.5 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) Acetyltransf_7 PF13508.1 EME78211.1 - 6.7e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME78211.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_16 PF00722.16 EME78213.1 - 2.4e-32 111.7 5.0 4.8e-32 110.7 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Adeno_E3_CR2 PF02439.10 EME78213.1 - 0.048 13.2 0.4 0.084 12.4 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.6 EME78213.1 - 0.063 12.8 0.2 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Podoplanin Na_H_antiport_2 PF13726.1 EME78213.1 - 0.083 12.8 0.2 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Na+-H+ antiporter family DUF1191 PF06697.7 EME78213.1 - 0.11 11.2 0.1 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Zn_clus PF00172.13 EME78214.1 - 6.8e-06 25.8 10.5 1.6e-05 24.7 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME78214.1 - 0.003 16.4 0.6 0.23 10.2 0.0 2.9 2 1 0 3 3 3 2 Fungal specific transcription factor domain Acetyltransf_1 PF00583.19 EME78215.1 - 9.4e-11 41.5 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME78215.1 - 9.3e-09 35.3 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME78215.1 - 3.7e-05 23.5 0.0 4.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME78215.1 - 6.4e-05 23.0 0.0 7.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME78215.1 - 0.0018 18.1 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME78215.1 - 0.0074 16.2 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME78215.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Mec-17 PF05301.6 EME78215.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 SelB-wing_3 PF09107.6 EME78215.1 - 0.13 11.6 0.5 0.33 10.3 0.2 1.8 1 1 1 2 2 2 0 Elongation factor SelB, winged helix GTP_EFTU PF00009.22 EME78216.1 - 2.1e-38 131.6 3.5 2.1e-38 131.6 2.4 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EME78216.1 - 1.9e-24 85.6 0.1 4.8e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EME78216.1 - 4.7e-12 45.8 2.9 3.3e-06 27.1 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME78216.1 - 2.7e-07 30.5 0.1 6.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EME78216.1 - 3.7e-06 26.4 0.0 1.1e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.16 EME78216.1 - 4.4e-06 26.0 0.0 8.9e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EME78216.1 - 1.1e-05 24.7 0.5 3.5e-05 23.1 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EME78216.1 - 2.5e-05 23.2 4.6 5.5e-05 22.0 3.2 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EME78216.1 - 3e-05 24.5 0.1 8.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EME78216.1 - 0.00031 20.2 1.0 0.00086 18.8 0.7 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EME78216.1 - 0.0013 18.1 0.2 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EME78216.1 - 0.0029 16.8 0.1 0.007 15.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3854 PF12965.2 EME78216.1 - 0.025 14.2 0.2 0.072 12.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) MutL_C PF08676.6 EME78216.1 - 0.17 11.4 1.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 MutL C terminal dimerisation domain Dynamin_N PF00350.18 EME78216.1 - 2.4 7.9 7.8 7.7 6.2 0.1 3.3 3 1 1 4 4 4 0 Dynamin family PAN_4 PF14295.1 EME78218.1 - 2.6e-14 52.6 1.7 3.9e-06 26.4 0.1 2.5 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 EME78218.1 - 0.0069 16.2 0.9 1.8 8.4 0.1 2.5 2 0 0 2 2 2 2 PAN-like domain zf-H2C2 PF09337.5 EME78221.1 - 5.3e-21 73.7 4.8 8.1e-21 73.1 3.3 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EME78221.1 - 3.2e-05 23.9 0.0 8.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME78221.1 - 0.0029 17.6 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EME78221.1 - 0.0088 16.2 0.1 0.21 11.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain RVT_1 PF00078.22 EME78223.1 - 0.0011 18.4 0.0 0.0012 18.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 EME78224.1 - 1e-47 162.4 0.0 1.2e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME78224.1 - 1.2e-27 96.6 0.0 1.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME78224.1 - 0.0014 18.3 0.3 0.0033 17.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME78224.1 - 0.003 16.5 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME78224.1 - 0.0069 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EME78224.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PKD_channel PF08016.7 EME78225.1 - 0.029 12.8 13.5 0.31 9.3 1.4 2.3 2 0 0 2 2 2 0 Polycystin cation channel PAS_9 PF13426.1 EME78226.1 - 1.3e-30 105.8 0.0 1e-16 61.2 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EME78226.1 - 9e-16 57.7 0.0 1.1e-09 38.2 0.0 3.7 4 0 0 4 4 4 3 PAS fold GATA PF00320.22 EME78226.1 - 2.1e-14 52.5 7.1 5.5e-14 51.2 4.9 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EME78226.1 - 7.3e-14 51.5 0.0 7.4e-06 25.7 0.0 3.8 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.1 EME78226.1 - 7.9e-12 45.1 0.0 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EME78226.1 - 1.5e-06 28.2 0.0 0.38 10.8 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.6 EME78226.1 - 0.0036 17.7 0.0 1.9 8.9 0.0 3.5 3 0 0 3 3 3 1 PAS fold Cytochrom_c3_2 PF14537.1 EME78226.1 - 0.036 14.4 0.5 0.085 13.2 0.4 1.6 1 0 0 1 1 1 0 Cytochrome c3 PAS_8 PF13188.1 EME78226.1 - 0.057 13.3 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 PAS domain ABC2_membrane PF01061.19 EME78227.1 - 7.3e-91 302.9 61.9 2.6e-48 163.9 13.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EME78227.1 - 8.6e-37 126.4 0.0 9.8e-18 64.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EME78227.1 - 9.6e-37 124.7 0.3 5.7e-30 103.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EME78227.1 - 1.2e-19 70.1 0.0 3.9e-19 68.5 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EME78227.1 - 1.3e-07 31.2 0.0 0.00016 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EME78227.1 - 1.2e-05 24.4 42.0 0.0025 16.9 14.6 3.7 3 1 0 3 3 3 2 ABC-2 family transporter protein DUF258 PF03193.11 EME78227.1 - 0.0001 21.5 1.3 0.0027 16.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME78227.1 - 0.00014 21.8 0.2 0.0021 18.0 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.1 EME78227.1 - 0.00079 18.9 2.2 0.014 14.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EME78227.1 - 0.0017 18.2 0.1 0.07 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME78227.1 - 0.0054 17.0 0.0 0.059 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME78227.1 - 0.0094 16.0 0.2 0.86 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EME78227.1 - 0.012 15.0 1.6 0.092 12.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EME78227.1 - 0.012 16.3 0.0 0.17 12.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EME78227.1 - 0.017 14.6 0.1 8 5.8 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family SMC_N PF02463.14 EME78227.1 - 0.019 14.1 0.0 0.34 10.0 0.0 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 EME78227.1 - 0.037 13.6 0.9 0.41 10.2 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EME78227.1 - 0.038 13.4 0.6 6.4 6.1 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.7 EME78227.1 - 0.043 13.4 1.6 2.6 7.6 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EME78227.1 - 0.1 12.5 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME78227.1 - 0.17 11.8 4.7 0.086 12.7 0.5 2.6 3 0 0 3 3 3 0 AAA domain DUF2681 PF10883.3 EME78227.1 - 0.25 11.5 1.0 3.4 7.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ABC2_membrane_2 PF12679.2 EME78227.1 - 5.4 5.7 34.0 0.016 14.0 8.4 2.8 3 0 0 3 3 2 0 ABC-2 family transporter protein ABC_membrane PF00664.18 EME78228.1 - 6.9e-09 35.5 0.2 1.4e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EME78228.1 - 0.0017 17.6 0.1 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Imm35 PF15581.1 EME78228.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 35 SMC_N PF02463.14 EME78229.1 - 3.2e-67 225.9 41.2 2.8e-66 222.9 28.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME78229.1 - 3.2e-26 91.6 0.1 1.3e-25 89.6 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EME78229.1 - 5.5e-13 49.5 2.2 4e-05 23.7 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EME78229.1 - 0.00015 21.1 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EME78229.1 - 0.00025 20.7 121.3 0.0025 17.4 12.3 7.3 2 2 7 9 9 9 5 IncA protein Reo_sigmaC PF04582.7 EME78229.1 - 0.026 13.7 35.4 0.14 11.3 1.7 5.7 2 2 5 7 7 7 0 Reovirus sigma C capsid protein Aldedh PF00171.17 EME78230.1 - 1.9e-121 405.6 0.5 4.9e-101 338.3 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LRS4 PF10422.4 EME78231.1 - 1.6 7.9 8.0 2 7.7 5.6 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Uso1_p115_C PF04871.8 EME78231.1 - 2.1 8.2 4.7 0.36 10.7 0.6 1.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fungal_trans PF04082.13 EME78232.1 - 1.2e-28 99.7 0.0 1.7e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78232.1 - 4e-09 36.2 9.0 7e-09 35.4 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF92 PF01940.11 EME78233.1 - 1.6e-54 184.4 10.7 2e-54 184.1 7.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Anophelin PF10731.4 EME78234.1 - 0.68 10.0 2.4 1.5 9.0 1.7 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Mito_carr PF00153.22 EME78235.1 - 2.9e-46 155.0 9.6 5.6e-17 61.2 0.2 4.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1314 PF07013.6 EME78235.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Glyco_transf_15 PF01793.11 EME78236.1 - 2.6e-144 480.2 7.6 3.2e-144 479.9 5.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.2 EME78236.1 - 0.29 11.1 2.6 0.52 10.3 1.8 1.4 1 0 0 1 1 1 0 EGF domain PAT1 PF09770.4 EME78237.1 - 1.1e-213 711.8 16.3 3.2e-213 710.3 11.3 1.6 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AKNA PF12443.3 EME78237.1 - 0.0012 18.8 0.0 0.0048 16.9 0.0 2.1 1 0 0 1 1 1 1 AT-hook-containing transcription factor DUF3926 PF13080.1 EME78237.1 - 0.06 12.8 1.8 0.099 12.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Macro PF01661.16 EME78238.1 - 1e-16 60.8 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Macro domain UCR_TM PF02921.9 EME78239.1 - 1.1e-18 67.1 0.2 2e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EME78239.1 - 5.7e-17 61.0 0.0 1.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Replicase PF03090.12 EME78239.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Replicase family Glycos_transf_1 PF00534.15 EME78240.1 - 9.8e-31 106.4 0.0 1.3e-29 102.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME78240.1 - 6.3e-10 39.3 0.0 1.7e-07 31.4 0.0 3.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME78240.1 - 1.2e-07 31.6 0.1 4.7e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EME78240.1 - 1.6e-07 31.6 0.2 5.3e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EME78240.1 - 3.4e-05 24.0 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_3 PF12000.3 EME78240.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Gkycosyl transferase family 4 group Acyltransferase PF01553.16 EME78241.1 - 1.9e-16 59.6 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Fungal_trans_2 PF11951.3 EME78242.1 - 5.2e-09 35.1 3.6 5.2e-09 35.1 2.5 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78242.1 - 1.3e-06 28.1 12.2 2.5e-06 27.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME78243.1 - 4.8e-35 120.9 23.6 4.8e-35 120.9 16.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EME78243.1 - 0.0002 21.0 6.1 0.007 16.1 0.1 2.9 3 0 0 3 3 3 2 MFS_1 like family Syja_N PF02383.13 EME78244.1 - 1.6e-90 303.0 0.1 8.6e-90 300.7 0.0 2.1 3 0 0 3 3 3 1 SacI homology domain ThiF PF00899.16 EME78245.1 - 4.1e-52 175.6 0.0 9.6e-32 109.6 0.1 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EME78245.1 - 2e-39 134.6 0.1 5e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EME78245.1 - 1.5e-38 130.2 5.1 2.7e-27 94.1 0.4 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EME78245.1 - 2.1e-25 87.8 2.1 4.1e-21 74.1 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Zn_clus PF00172.13 EME78246.1 - 2.3e-10 40.1 9.5 2.8e-10 39.9 6.6 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4206 PF13901.1 EME78246.1 - 0.13 11.8 3.3 0.22 11.0 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) MamL-1 PF09596.5 EME78246.1 - 2.3 8.1 6.2 2.8 7.7 4.1 1.4 1 1 0 1 1 1 0 MamL-1 domain zf-C2H2 PF00096.21 EME78247.1 - 8.7e-11 41.5 14.3 6.4e-06 26.2 4.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME78247.1 - 1.1e-07 31.8 18.3 2.5e-05 24.3 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME78247.1 - 2e-06 27.7 14.2 0.00024 21.2 4.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-UBP PF02148.14 EME78247.1 - 0.13 12.3 5.7 0.42 10.7 3.9 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein RRN7 PF11781.3 EME78247.1 - 0.46 10.0 3.4 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Git3 PF11710.3 EME78248.1 - 1.9e-51 174.5 12.2 1.9e-51 174.5 8.4 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EME78248.1 - 1.1e-26 92.3 3.8 3.1e-26 90.9 2.6 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term zf-C2H2_4 PF13894.1 EME78249.1 - 6.6e-12 44.8 15.2 0.0016 18.6 1.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EME78249.1 - 4.7e-11 42.3 19.3 0.00018 21.6 1.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME78249.1 - 2.2e-06 27.6 22.2 0.0013 18.9 0.5 4.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-Di19 PF05605.7 EME78249.1 - 0.37 10.9 10.3 0.067 13.3 2.7 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.13 EME78249.1 - 0.77 10.1 13.2 2.1 8.7 0.5 3.3 2 1 2 4 4 4 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EME78249.1 - 1.1 9.5 7.5 3.7 7.8 0.7 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME78249.1 - 1.5 8.9 7.7 13 5.9 1.3 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EME78249.1 - 5.4 7.0 9.1 3.3 7.7 1.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EME78249.1 - 8.2 6.2 7.5 1.1 9.0 0.9 2.3 2 0 0 2 2 2 0 BED zinc finger DUF3328 PF11807.3 EME78253.1 - 2.2e-33 115.7 0.1 2.4e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EME78254.1 - 4e-22 78.9 0.0 4.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EME78256.1 - 1.8e-25 89.9 0.1 2.1e-25 89.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PI31_Prot_N PF11566.3 EME78257.1 - 1.8e-34 118.5 0.0 2.4e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EME78257.1 - 5.7e-15 55.7 19.7 5.7e-15 55.7 13.7 2.8 3 1 1 4 4 4 1 PI31 proteasome regulator REV PF00424.13 EME78258.1 - 0.0037 17.1 6.4 0.0048 16.7 4.4 1.2 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) Peptidase_A21 PF03566.8 EME78258.1 - 0.16 10.0 4.1 0.17 9.9 2.9 1.1 1 0 0 1 1 1 0 Peptidase family A21 DUF3112 PF11309.3 EME78259.1 - 7.3e-28 97.3 11.1 3.6e-27 95.1 0.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) B12D PF06522.6 EME78259.1 - 0.51 10.0 4.2 1.6 8.5 0.6 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Glyco_hydro_92 PF07971.7 EME78260.1 - 3.5e-161 537.2 3.1 4.6e-161 536.8 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 F-box-like PF12937.2 EME78261.1 - 0.08 12.6 0.4 0.25 11.1 0.2 1.9 1 1 0 1 1 1 0 F-box-like PC_rep PF01851.17 EME78262.1 - 4.4e-16 58.1 17.5 3.8e-05 23.6 0.1 7.4 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EME78262.1 - 0.0084 16.3 2.0 1.8 8.8 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats RIO1 PF01163.17 EME78263.1 - 3.7e-41 140.5 0.0 5.6e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EME78263.1 - 3.1e-28 97.6 0.0 6.7e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EME78263.1 - 8.9e-08 32.1 1.9 0.00067 19.4 0.3 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EME78263.1 - 2.1e-06 26.9 0.1 0.0044 16.1 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.23 EME78264.1 - 5.3e-11 43.0 2.7 2.1e-09 37.8 0.5 3.0 2 1 0 2 2 2 1 SET domain TPR_8 PF13181.1 EME78264.1 - 0.029 14.1 1.8 0.092 12.5 1.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyridox_oxase_2 PF12766.2 EME78265.1 - 3.2e-20 72.2 0.0 7.6e-20 71.1 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Thionin PF00321.12 EME78265.1 - 0.11 12.7 0.6 0.27 11.4 0.4 1.6 1 0 0 1 1 1 0 Plant thionin RelB_N PF12910.2 EME78266.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal Spc7_N PF15402.1 EME78266.1 - 0.53 8.2 3.9 0.68 7.8 2.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MFS_1 PF07690.11 EME78268.1 - 2.4e-34 118.6 21.4 3.6e-34 118.0 14.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.19 EME78268.1 - 4.1 6.7 13.1 0.32 10.4 1.4 2.8 2 1 0 2 2 2 0 Fatty acid desaturase adh_short PF00106.20 EME78270.1 - 2.9e-14 53.3 0.2 3.8e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME78270.1 - 4.1e-08 33.3 0.1 6.3e-08 32.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME78270.1 - 6.4e-05 22.7 0.1 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EME78270.1 - 0.0015 17.7 0.1 0.02 14.1 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family DUF866 PF05907.8 EME78272.1 - 1.1e-50 171.3 0.7 1.2e-50 171.1 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.1 EME78272.1 - 0.044 13.5 1.2 0.044 13.5 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4379) PHD PF00628.24 EME78272.1 - 0.074 12.7 1.0 0.14 11.8 0.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-like PF04071.7 EME78272.1 - 0.087 12.5 0.3 0.087 12.5 0.2 2.0 1 1 1 2 2 2 0 Cysteine-rich small domain Lar_restr_allev PF14354.1 EME78272.1 - 0.42 10.9 2.6 3.3 8.0 0.1 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF3716 PF12511.3 EME78272.1 - 1.6 8.3 5.5 3.2 7.4 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) zf-DNL PF05180.7 EME78272.1 - 2.7 7.7 5.2 17 5.2 0.2 2.3 1 1 1 2 2 2 0 DNL zinc finger Ras PF00071.17 EME78273.1 - 2.2e-59 199.4 0.3 2.6e-59 199.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME78273.1 - 1.5e-18 67.4 0.1 2.1e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME78273.1 - 2e-08 33.7 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME78273.1 - 1e-06 28.3 0.1 1.8e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME78273.1 - 0.0043 16.3 0.0 0.0073 15.5 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EME78273.1 - 0.0052 16.7 0.0 0.0062 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EME78273.1 - 0.011 14.8 0.2 0.016 14.3 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EME78273.1 - 0.11 11.8 0.6 1.5 8.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Cofilin_ADF PF00241.15 EME78274.1 - 4e-10 39.6 0.0 4.7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Csm1 PF12539.3 EME78274.1 - 0.12 12.8 0.2 0.47 10.9 0.1 1.8 1 1 1 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 MoCF_biosynth PF00994.19 EME78275.1 - 1.4e-34 118.5 0.0 2.1e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain FAD_syn PF06574.7 EME78275.1 - 0.098 12.2 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 FAD synthetase AA_permease_2 PF13520.1 EME78277.1 - 4e-35 121.1 40.7 5e-35 120.8 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME78277.1 - 3.5e-16 58.5 34.1 6.1e-16 57.8 23.6 1.3 1 0 0 1 1 1 1 Amino acid permease DUF2615 PF11027.3 EME78277.1 - 6.2 6.8 5.1 2.8 7.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Pkinase PF00069.20 EME78278.1 - 9.9e-59 198.5 0.0 2.1e-58 197.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME78278.1 - 5.1e-20 71.6 0.0 1.6e-19 70.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EME78278.1 - 0.031 14.0 1.3 0.059 13.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EME78278.1 - 0.24 10.3 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Acetyltransf_1 PF00583.19 EME78281.1 - 1.7e-06 27.9 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME78281.1 - 4.7e-05 23.4 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME78281.1 - 0.00018 21.6 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pho86 PF11124.3 EME78281.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 FUSC_2 PF13515.1 EME78281.1 - 0.021 14.7 0.4 0.032 14.1 0.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Acetyltransf_CG PF14542.1 EME78281.1 - 0.022 14.6 0.1 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EME78281.1 - 0.048 13.2 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ATPase_gene1 PF09527.5 EME78281.1 - 0.19 11.5 3.6 0.35 10.7 2.5 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) Perilipin PF03036.11 EME78283.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Perilipin family PDE6_gamma PF04868.7 EME78283.1 - 0.1 12.4 0.3 0.37 10.6 0.5 1.7 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit CLTH PF10607.4 EME78284.1 - 1.8e-29 102.2 0.2 2.4e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EME78284.1 - 2.4e-08 33.4 0.2 9.1e-08 31.6 0.0 2.0 2 0 0 2 2 2 1 LisH TINF2_N PF14973.1 EME78284.1 - 0.12 12.4 0.3 0.19 11.8 0.2 1.5 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus PRK PF00485.13 EME78285.1 - 2e-57 193.8 0.0 2.8e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EME78285.1 - 2.9e-37 127.9 0.0 4.5e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EME78285.1 - 1.4e-08 35.5 0.0 3.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EME78285.1 - 2.9e-05 23.7 0.1 8.3e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EME78285.1 - 0.00082 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 EME78285.1 - 0.0036 17.0 0.0 0.0091 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Zeta_toxin PF06414.7 EME78285.1 - 0.0039 16.2 0.0 0.0087 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EME78285.1 - 0.023 14.5 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EME78285.1 - 0.031 12.9 0.1 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus MobB PF03205.9 EME78285.1 - 0.032 13.9 0.0 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EME78285.1 - 0.039 14.2 0.5 0.1 12.9 0.1 1.8 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 EME78285.1 - 0.08 12.6 0.0 0.36 10.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EME78285.1 - 0.095 12.0 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME78285.1 - 0.12 12.6 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_26 PF13500.1 EME78285.1 - 0.2 11.2 0.5 9.1 5.8 0.2 3.0 2 1 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.9 EME78286.1 - 0.13 10.0 0.0 0.13 10.0 0.0 1.0 1 0 0 1 1 1 0 Helicase Acetyltransf_7 PF13508.1 EME78289.1 - 3.1e-08 33.6 0.0 6.2e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME78289.1 - 1.8e-06 27.8 0.0 3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME78289.1 - 0.00067 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EME78289.1 - 0.0014 18.4 0.1 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME78289.1 - 0.0043 17.1 0.0 0.0084 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA_int_endo PF01974.12 EME78290.1 - 1.8e-16 59.7 0.0 4.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pol_alpha_B_N PF08418.5 EME78290.1 - 0.62 9.5 4.6 0.93 8.9 3.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MAT_Alpha1 PF04769.7 EME78291.1 - 9e-18 64.3 0.1 8.7e-11 41.5 0.0 2.8 1 1 2 3 3 3 2 Mating-type protein MAT alpha 1 Anp1 PF03452.9 EME78292.1 - 1.2e-119 398.4 0.3 3.3e-119 397.0 0.0 1.7 2 0 0 2 2 2 1 Anp1 G6PD_bact PF10786.4 EME78292.1 - 0.022 14.2 0.8 0.022 14.2 0.6 1.7 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Glyco_tranf_2_4 PF13704.1 EME78292.1 - 0.023 14.9 0.7 0.095 13.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Atg14 PF10186.4 EME78292.1 - 0.063 12.2 5.2 0.13 11.2 3.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2265 PF10023.4 EME78292.1 - 0.41 9.7 4.4 0.66 9.0 3.0 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DUF1943 PF09172.6 EME78292.1 - 0.51 9.1 2.9 0.22 10.3 0.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Rad54_N PF08658.5 EME78292.1 - 0.87 9.3 9.6 0.59 9.8 5.3 1.6 1 1 1 2 2 2 0 Rad54 N terminal HSP70 PF00012.15 EME78292.1 - 1.3 6.7 10.0 2.1 6.1 7.0 1.2 1 0 0 1 1 1 0 Hsp70 protein ADIP PF11559.3 EME78292.1 - 4 7.3 13.7 1.6 8.6 7.8 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sec7 PF01369.15 EME78293.1 - 5.2e-63 212.1 0.2 8.2e-63 211.5 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EME78293.1 - 3e-20 72.3 0.0 7.7e-13 48.2 0.1 2.9 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Zn_clus PF00172.13 EME78294.1 - 4.6e-05 23.2 5.9 9e-05 22.3 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_10 PF13596.1 EME78294.1 - 0.0032 17.6 0.0 0.014 15.6 0.0 2.0 2 0 0 2 2 2 1 PAS domain OB_NTP_bind PF07717.11 EME78297.1 - 5.4e-28 97.1 0.0 1.5e-26 92.4 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME78297.1 - 4.4e-27 94.0 0.1 1.6e-26 92.3 0.1 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) S1 PF00575.18 EME78297.1 - 6.2e-13 48.6 0.7 6.2e-13 48.6 0.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Helicase_C PF00271.26 EME78297.1 - 3.1e-12 46.1 0.0 1.1e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME78297.1 - 1.7e-05 24.3 0.1 4.1e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME78297.1 - 0.00011 22.2 0.2 0.0007 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME78297.1 - 0.00018 20.5 0.0 0.00091 18.2 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.1 EME78297.1 - 0.0096 15.5 0.1 0.097 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME78297.1 - 0.04 13.8 0.2 0.34 10.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EME78297.1 - 0.057 12.6 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 EME78297.1 - 0.069 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain APH PF01636.18 EME78298.1 - 1.1e-17 64.5 0.0 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME78298.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EME78298.1 - 0.0029 16.9 0.0 0.035 13.4 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 EME78298.1 - 0.0085 15.0 0.0 0.99 8.3 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase Pkinase PF00069.20 EME78298.1 - 0.011 14.8 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EME78298.1 - 0.054 12.1 0.0 0.097 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EME78298.1 - 0.068 12.3 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ras PF00071.17 EME78299.1 - 3.3e-58 195.6 0.3 4.3e-58 195.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME78299.1 - 5.8e-21 75.1 0.1 8.1e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME78299.1 - 4.1e-16 58.7 0.1 4.6e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME78299.1 - 2.1e-07 30.5 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EME78299.1 - 9.8e-07 28.1 0.1 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EME78299.1 - 2.6e-06 26.7 0.1 3.3e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME78299.1 - 3.1e-05 23.8 0.0 4.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME78299.1 - 0.0021 17.3 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EME78299.1 - 0.026 14.3 0.1 2.8 7.7 0.0 2.7 2 1 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EME78299.1 - 0.096 12.3 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EME78299.1 - 0.11 12.1 0.1 3.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EME78299.1 - 0.13 12.4 0.0 2.3 8.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Nop53 PF07767.6 EME78300.1 - 6.5e-89 298.6 36.9 8.7e-89 298.2 25.6 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF908 PF06012.7 EME78300.1 - 0.14 11.4 4.2 0.22 10.8 2.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) NIR_SIR PF01077.17 EME78303.1 - 3e-51 172.8 0.0 3.2e-44 150.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EME78303.1 - 8.3e-32 108.6 0.0 4e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EME78303.1 - 5.3e-29 101.0 0.0 1.1e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EME78303.1 - 2.9e-10 40.0 0.3 1.3e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DHC_N1 PF08385.7 EME78303.1 - 0.18 10.1 0.0 0.29 9.4 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 MOZ_SAS PF01853.13 EME78306.1 - 4.7e-84 280.3 0.0 6.5e-84 279.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EME78306.1 - 3.2e-21 74.7 0.0 6.2e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EME78306.1 - 0.0076 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1918 PF08940.6 EME78306.1 - 0.027 13.7 0.0 0.069 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) RNase_T PF00929.19 EME78307.1 - 5.2e-22 78.8 0.0 6.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Glyco_hydro_92 PF07971.7 EME78309.1 - 2.5e-142 475.0 1.5 2.9e-142 474.8 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 FMO-like PF00743.14 EME78310.1 - 3.8e-49 167.2 0.0 1.2e-48 165.5 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME78310.1 - 2.4e-23 83.2 0.0 5.1e-23 82.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME78310.1 - 1.4e-08 34.8 0.0 2.3e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME78310.1 - 1.1e-05 24.5 0.0 6.3e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EME78310.1 - 1.4e-05 25.3 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME78310.1 - 2.3e-05 24.3 0.0 5.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME78310.1 - 5.9e-05 22.8 0.1 0.0029 17.3 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EME78310.1 - 0.0036 16.2 0.0 0.34 9.7 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME78310.1 - 0.029 12.8 0.0 0.058 11.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EME78310.1 - 0.12 11.4 0.2 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family RTA1 PF04479.8 EME78311.1 - 3.9e-19 69.0 2.5 8.2e-19 67.9 1.7 1.4 1 1 0 1 1 1 1 RTA1 like protein Tetraspannin PF00335.15 EME78311.1 - 0.04 13.1 4.2 0.7 9.1 0.9 2.2 2 0 0 2 2 2 0 Tetraspanin family DUF2754 PF10953.3 EME78311.1 - 0.079 13.0 2.4 0.083 12.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) 2TM PF13239.1 EME78311.1 - 1.3 9.1 5.5 7 6.7 2.1 2.4 2 0 0 2 2 2 0 2TM domain NAD_binding_10 PF13460.1 EME78313.1 - 0.00034 20.6 0.0 0.00041 20.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME78313.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein PYC_OADA PF02436.13 EME78314.1 - 0.077 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain PepSY_TM PF03929.11 EME78314.1 - 0.085 13.2 0.9 0.44 11.0 0.6 2.3 1 0 0 1 1 1 0 PepSY-associated TM helix Sugar_tr PF00083.19 EME78315.1 - 3.8e-130 434.4 31.1 4.4e-130 434.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78315.1 - 2.9e-24 85.4 34.8 3.2e-16 59.0 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Invasin_D3 PF09134.5 EME78316.1 - 0.037 13.8 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Invasin, domain 3 Peripla_BP_1 PF00532.16 EME78318.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Snf7 PF03357.16 EME78320.1 - 7e-23 80.8 11.1 7e-23 80.8 7.7 1.7 1 1 1 2 2 2 1 Snf7 DUF4404 PF14357.1 EME78320.1 - 0.2 12.0 7.5 3.1 8.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) YlqD PF11068.3 EME78320.1 - 3.7 7.6 10.7 0.63 10.0 4.2 2.0 2 0 0 2 2 2 0 YlqD protein CS PF04969.11 EME78321.1 - 4.7e-10 39.8 0.5 7.9e-10 39.1 0.3 1.5 1 1 0 1 1 1 1 CS domain RabGAP-TBC PF00566.13 EME78322.1 - 1e-42 146.0 0.2 1.4e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_18 PF00704.23 EME78324.1 - 2.3e-94 316.6 0.8 2.6e-94 316.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ProRS-C_1 PF09180.6 EME78325.1 - 8.4e-22 76.8 0.1 1.7e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EME78325.1 - 7.1e-19 68.0 0.1 1.2e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME78325.1 - 6e-17 61.3 0.0 1.2e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Lysozyme_like PF13702.1 EME78327.1 - 0.076 12.4 0.3 0.19 11.2 0.2 1.7 1 1 0 1 1 1 0 Lysozyme-like DUF2419 PF10343.4 EME78329.1 - 5.3e-99 331.0 0.0 6.4e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) ThiF PF00899.16 EME78330.1 - 3.7e-39 133.6 0.1 9.6e-39 132.3 0.0 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EME78330.1 - 8.6e-28 95.7 0.2 1.8e-27 94.7 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EME78330.1 - 7.8e-21 73.1 0.7 7.8e-21 73.1 0.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EME78330.1 - 4.3e-06 26.7 1.3 6.4e-06 26.1 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EME78330.1 - 1.1e-05 25.5 0.2 3.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME78330.1 - 0.00063 19.8 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EME78330.1 - 0.0089 16.4 0.1 0.045 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME78330.1 - 0.011 15.7 0.0 0.064 13.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Saccharop_dh PF03435.13 EME78330.1 - 0.03 13.3 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFA PF04828.9 EME78331.1 - 6.1e-12 45.3 0.0 6.1e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PSDC PF12588.3 EME78332.1 - 8e-52 174.5 0.0 1.2e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EME78332.1 - 2.3e-36 124.9 0.1 5.4e-36 123.7 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EME78332.1 - 0.032 13.8 0.1 8.7 6.0 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EME78332.1 - 0.12 12.0 0.1 0.66 9.6 0.1 2.1 2 0 0 2 2 2 0 Biotin-requiring enzyme vMSA PF00695.14 EME78333.1 - 0.025 13.7 0.0 0.025 13.7 0.0 2.1 1 1 0 2 2 2 0 Major surface antigen from hepadnavirus MSA-2c PF12238.3 EME78333.1 - 1.2 8.7 14.1 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c HET PF06985.6 EME78334.1 - 5.5e-27 94.6 0.2 6.7e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SprT-like PF10263.4 EME78335.1 - 1.1e-05 25.1 0.5 0.038 13.6 0.0 2.6 2 1 1 3 3 3 2 SprT-like family zf-Di19 PF05605.7 EME78335.1 - 6.1e-05 23.0 3.7 0.014 15.5 0.3 2.6 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding NUDIX PF00293.23 EME78337.1 - 8.1e-27 93.5 0.0 1.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MCM PF00493.18 EME78338.1 - 1.2e-135 451.6 0.2 1.2e-135 451.6 0.2 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EME78338.1 - 7.3e-22 78.1 0.4 3.9e-21 75.7 0.1 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME78338.1 - 4.1e-08 32.6 0.0 7.8e-07 28.4 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME78338.1 - 0.001 18.5 0.1 0.0028 17.1 0.1 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EME78338.1 - 0.0018 17.9 0.0 0.0048 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME78338.1 - 0.0056 16.4 0.0 0.034 13.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TFCD_C PF12612.3 EME78339.1 - 2e-20 73.0 6.0 6.5e-17 61.5 3.5 3.8 2 1 0 2 2 2 2 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EME78339.1 - 0.00017 21.7 8.4 1.9 8.7 0.0 5.8 5 1 1 6 6 6 2 HEAT repeats IFRD PF05004.8 EME78339.1 - 0.1 11.6 9.2 0.11 11.5 0.0 3.8 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EME78339.1 - 5.7 7.5 24.6 1.5 9.4 0.0 7.9 8 1 2 10 10 10 0 HEAT-like repeat Pentapeptide_4 PF13599.1 EME78340.1 - 1.7e-08 34.1 4.5 0.00014 21.6 0.1 3.1 2 1 0 2 2 2 2 Pentapeptide repeats (9 copies) Beta_helix PF13229.1 EME78340.1 - 0.051 13.3 0.5 0.38 10.4 0.0 2.0 1 1 1 2 2 2 0 Right handed beta helix region zf-C3HC4_3 PF13920.1 EME78341.1 - 4.1e-08 32.7 11.3 9.1e-08 31.6 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME78341.1 - 4.8 7.2 14.7 10 6.2 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADP_ribosyl_GH PF03747.9 EME78342.1 - 2.3e-29 103.0 1.1 3.8e-29 102.3 0.8 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase WD40 PF00400.27 EME78343.1 - 2.5e-34 115.8 8.7 5e-08 32.5 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EME78343.1 - 1.6e-06 26.5 9.0 0.0052 14.9 0.1 4.4 3 2 0 4 4 4 3 Nucleoporin Nup120/160 DUF4164 PF13747.1 EME78343.1 - 0.021 14.9 5.4 0.048 13.7 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) APG6 PF04111.7 EME78343.1 - 0.076 12.0 7.0 0.11 11.5 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EME78343.1 - 0.12 11.0 3.9 0.59 8.7 2.8 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein PQQ_2 PF13360.1 EME78343.1 - 0.12 11.7 2.5 0.27 10.6 0.1 2.4 2 1 1 3 3 3 0 PQQ-like domain IncA PF04156.9 EME78343.1 - 0.16 11.5 5.7 0.25 10.8 3.9 1.2 1 0 0 1 1 1 0 IncA protein F-box PF00646.28 EME78344.1 - 0.00022 20.7 0.4 0.00077 19.0 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME78344.1 - 0.0006 19.4 0.4 0.0041 16.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like Npa1 PF11707.3 EME78345.1 - 4.9e-59 199.9 0.2 1e-57 195.6 0.0 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal DUF3243 PF11588.3 EME78345.1 - 0.03 14.3 0.1 0.11 12.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) 5-nucleotidase PF06189.7 EME78350.1 - 0.022 13.5 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase Arb1 PF09692.5 EME78353.1 - 3.2e-82 276.5 0.0 4.2e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.12 EME78353.1 - 9.7e-13 47.7 0.0 2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 La domain ADH_zinc_N PF00107.21 EME78354.1 - 1.3e-30 105.6 0.1 2.2e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME78354.1 - 4.1e-19 69.7 0.0 1e-18 68.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME78354.1 - 5.2e-10 39.0 0.2 1.3e-08 34.5 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EME78355.1 - 4.3e-34 117.8 0.0 5.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME78355.1 - 1.6e-13 50.9 0.0 2.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME78355.1 - 1.3e-12 47.7 0.0 1.9e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EME78355.1 - 0.014 14.3 0.2 0.028 13.3 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EME78355.1 - 0.016 14.6 0.1 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME78355.1 - 0.036 13.8 0.2 0.084 12.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 EME78356.1 - 5.7e-09 36.1 0.0 8.4e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME78356.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAXNEB PF05625.6 EME78357.1 - 5.5e-103 344.5 0.0 6.1e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein DNA_mis_repair PF01119.14 EME78358.1 - 1.9e-30 104.7 0.0 3.4e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EME78358.1 - 1e-13 51.0 0.0 2.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME78358.1 - 2.6e-10 40.0 0.0 9.3e-10 38.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peroxidase_2 PF01328.12 EME78359.1 - 2.6e-16 59.1 0.1 4.2e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 RNA_pol_Rpb8 PF03870.10 EME78360.1 - 3.7e-36 124.3 0.0 4e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 EME78361.1 - 6.7e-09 35.4 0.1 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 EME78362.1 - 1.5e-56 191.0 0.0 1.7e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) HET PF06985.6 EME78365.1 - 5e-20 72.0 0.1 7.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 EME78366.1 - 1.6e-12 47.1 4.0 0.14 12.1 0.0 7.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EME78366.1 - 1.8e-10 41.0 0.1 0.0083 16.4 0.0 6.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME78366.1 - 1.7e-09 37.4 25.7 0.042 14.4 0.0 12.1 13 1 1 14 14 12 2 Tetratricopeptide repeat Suf PF05843.9 EME78366.1 - 5.2e-07 29.6 10.8 0.68 9.6 0.1 5.7 3 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EME78366.1 - 1.2e-06 27.9 16.5 0.0067 16.2 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME78366.1 - 1.2e-06 27.8 4.6 0.55 10.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME78366.1 - 2.6e-05 23.7 11.2 0.47 10.1 0.0 7.1 9 0 0 9 9 8 1 TPR repeat TPR_16 PF13432.1 EME78366.1 - 5.6e-05 23.7 13.8 0.49 11.1 0.0 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME78366.1 - 0.00015 21.3 14.0 0.021 14.6 0.0 7.5 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME78366.1 - 0.0002 21.3 5.2 1.8 8.9 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EME78366.1 - 0.0028 17.4 12.7 0.96 9.2 0.1 6.4 6 1 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_4 PF07721.9 EME78366.1 - 0.0074 16.6 1.8 0.81 10.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EME78366.1 - 0.0076 16.6 8.9 2.7 8.6 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EME78366.1 - 0.019 14.2 0.0 0.11 11.8 0.0 2.4 1 0 0 1 1 1 0 SHNi-TPR TPR_1 PF00515.23 EME78366.1 - 0.086 12.4 2.0 1.3 8.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME78366.1 - 0.16 11.9 0.0 0.16 11.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat HAT PF02184.11 EME78366.1 - 0.32 10.7 17.7 1.7 8.4 0.3 7.0 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat ATP-synt_D PF01813.12 EME78367.1 - 9.6e-62 208.0 5.2 1.2e-61 207.6 3.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D CAML PF14963.1 EME78367.1 - 0.18 11.1 3.6 0.24 10.7 0.9 2.2 3 0 0 3 3 3 0 Calcium signal-modulating cyclophilin ligand Sec62 PF03839.11 EME78367.1 - 0.7 9.2 4.5 1.2 8.5 3.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 YndJ PF14158.1 EME78368.1 - 0.004 16.2 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 YndJ-like protein Stn1_C PF12659.2 EME78368.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH p450 PF00067.17 EME78369.1 - 2e-33 115.6 0.0 2.3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MinE PF03776.9 EME78369.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE CoA_transf_3 PF02515.12 EME78370.1 - 2.6e-28 98.5 0.0 3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III IPK PF03770.11 EME78371.1 - 1.2e-52 178.4 0.0 1.6e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arteri_nucleo PF01481.11 EME78371.1 - 0.1 12.6 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein Aldedh PF00171.17 EME78372.1 - 2.4e-151 504.2 0.0 3e-151 503.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME78372.1 - 2.6e-05 23.1 0.0 5.2e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EME78372.1 - 0.11 11.7 0.0 15 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) eIF-1a PF01176.14 EME78374.1 - 4.4e-13 48.4 0.0 1.8e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EME78375.1 - 2.1e-115 385.8 19.2 8.2e-68 229.3 4.9 2.0 1 1 1 2 2 2 2 ALG3 protein SLAC1 PF03595.12 EME78377.1 - 1.9e-80 269.9 43.5 2.2e-80 269.8 30.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel BMFP PF04380.8 EME78378.1 - 0.019 15.1 0.4 4.4 7.5 0.1 2.9 2 0 0 2 2 2 0 Membrane fusogenic activity PPR_2 PF13041.1 EME78378.1 - 0.11 12.4 0.0 24 4.9 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family Synaptobrevin PF00957.16 EME78379.1 - 2.4e-30 103.9 0.0 3.4e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EME78379.1 - 6.6e-21 73.6 0.0 1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tautomerase_3 PF14832.1 EME78380.1 - 9.1e-12 45.1 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EME78380.1 - 0.0042 16.6 0.0 0.21 11.2 0.0 2.8 3 0 0 3 3 3 1 Tautomerase enzyme DIOX_N PF14226.1 EME78381.1 - 6.4e-24 84.7 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME78381.1 - 2.8e-18 66.0 0.0 4.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EME78382.1 - 1.9e-88 296.9 37.3 2.2e-88 296.7 25.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RhoGEF PF00621.15 EME78383.1 - 6.6e-23 81.5 0.3 1.4e-22 80.4 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EME78383.1 - 1.2e-05 24.9 0.0 9.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3507) DUF4407 PF14362.1 EME78383.1 - 0.0058 15.6 6.4 0.71 8.7 0.1 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4407) DUF4248 PF14053.1 EME78383.1 - 0.071 12.6 0.4 0.18 11.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) TSC22 PF01166.13 EME78383.1 - 0.1 12.5 0.5 0.73 9.8 0.3 2.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2036 PF09724.4 EME78384.1 - 1.9e-27 96.3 0.0 2.3e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Hemerythrin PF01814.18 EME78385.1 - 1.4e-13 51.1 6.6 1.9e-13 50.7 4.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RPAP1_N PF08621.5 EME78385.1 - 0.45 10.1 3.0 1.1 8.9 0.6 2.7 3 0 0 3 3 3 0 RPAP1-like, N-terminal Acetyltransf_3 PF13302.1 EME78386.1 - 6.4e-20 71.7 0.0 7.4e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME78386.1 - 1.6e-13 50.5 0.0 2.3e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EME78386.1 - 2.5e-08 33.9 0.0 3.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME78386.1 - 2.5e-06 27.1 0.1 5.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EME78386.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME78386.1 - 0.00084 19.4 0.0 0.00099 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME78386.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_31 PF01055.21 EME78387.1 - 1.3e-127 426.3 4.1 1.6e-127 426.0 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME78387.1 - 5.1e-06 26.2 0.2 3.9e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like DUF1420 PF07220.6 EME78387.1 - 0.33 9.2 0.0 0.47 8.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1420) COesterase PF00135.23 EME78388.1 - 2.6e-87 293.7 0.2 1e-77 262.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EME78388.1 - 7.3e-08 32.2 0.1 4.4e-07 29.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78388.1 - 0.011 15.4 0.1 0.034 13.8 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family DIM1 PF02966.11 EME78390.1 - 5.3e-70 233.0 0.3 6e-70 232.9 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EME78390.1 - 0.00062 19.8 0.5 0.0013 18.8 0.4 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EME78390.1 - 0.004 16.8 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME78390.1 - 0.061 13.3 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Glyco_hydro_47 PF01532.15 EME78391.1 - 6.5e-109 364.5 0.0 7.3e-109 364.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Asp PF00026.18 EME78392.1 - 1.7e-10 40.6 0.3 1.1e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Podoplanin PF05808.6 EME78392.1 - 0.019 14.5 0.3 0.031 13.8 0.2 1.3 1 0 0 1 1 1 0 Podoplanin DUF2668 PF10873.3 EME78392.1 - 0.028 14.5 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Herpes_gE PF02480.11 EME78392.1 - 0.074 11.3 0.2 0.11 10.7 0.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EME78392.1 - 9.6 5.8 6.8 0.75 9.3 1.3 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRR_9 PF14580.1 EME78393.1 - 9e-51 171.9 0.0 1.1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EME78393.1 - 1.9e-11 43.3 0.8 9.2e-06 25.1 0.1 3.6 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME78393.1 - 2.1e-08 33.7 1.9 1.9e-07 30.7 0.2 3.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EME78393.1 - 1 9.6 7.4 11 6.4 0.2 4.5 4 2 0 4 4 4 0 Leucine Rich Repeat Aldedh PF00171.17 EME78395.1 - 1.1e-132 442.6 0.0 1.3e-132 442.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME78395.1 - 1.7e-07 30.3 0.0 2.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pyr_redox_2 PF07992.9 EME78396.1 - 4.2e-21 75.7 0.0 6.8e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME78396.1 - 9.3e-14 51.6 0.0 5.7e-10 39.4 0.0 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EME78396.1 - 6.7e-06 25.0 0.1 2e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EME78396.1 - 1.1e-05 25.5 0.1 3e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EME78396.1 - 4.3e-05 23.0 0.2 0.00017 21.1 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EME78396.1 - 0.00064 18.9 0.4 0.00064 18.9 0.3 2.0 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.1 EME78396.1 - 0.036 14.1 0.0 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pox_D2 PF04701.8 EME78397.1 - 0.051 13.5 0.6 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 Pox virus D2 protein Phage_XkdX PF09693.5 EME78397.1 - 0.41 10.2 1.6 16 5.0 0.1 2.4 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Cu-oxidase_3 PF07732.10 EME78400.1 - 6e-42 142.1 1.7 6e-42 142.1 1.2 3.1 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EME78400.1 - 1e-38 132.7 1.5 2.2e-38 131.6 0.2 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME78400.1 - 2.7e-36 124.0 0.3 2.7e-36 124.0 0.2 3.2 3 0 0 3 3 3 1 Multicopper oxidase TSC22 PF01166.13 EME78401.1 - 0.061 13.3 0.2 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 EME78401.1 - 0.14 12.4 0.4 0.14 12.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Zein-binding PF04576.10 EME78401.1 - 0.15 12.2 2.1 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Zein-binding NYD-SP28_assoc PF14775.1 EME78401.1 - 0.2 11.3 1.7 1.2 8.9 0.8 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 EME78401.1 - 0.62 9.8 4.3 0.17 11.6 0.3 2.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper tRNA_int_end_N2 PF12928.2 EME78403.1 - 1.9e-23 81.6 0.0 3.4e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Pkinase PF00069.20 EME78404.1 - 1.9e-34 118.9 0.0 2.1e-22 79.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME78404.1 - 1.7e-14 53.5 0.0 1e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EME78404.1 - 0.001 18.8 2.2 0.024 14.3 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EME78404.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GDA1_CD39 PF01150.12 EME78405.1 - 1.1e-107 360.2 0.0 1.5e-107 359.8 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family F-box-like PF12937.2 EME78406.1 - 5.7e-05 22.7 0.0 0.00016 21.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF4495 PF14906.1 EME78406.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) Thioredoxin PF00085.15 EME78407.1 - 1.6e-29 101.6 0.3 1.9e-29 101.4 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME78407.1 - 3.4e-06 27.2 0.5 4.5e-05 23.6 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME78407.1 - 3.5e-05 23.8 0.1 0.0014 18.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EME78407.1 - 9e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME78407.1 - 0.0015 18.4 0.4 0.0024 17.8 0.3 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EME78407.1 - 0.0073 15.9 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 EME78407.1 - 0.028 13.1 0.0 0.03 13.0 0.0 1.0 1 0 0 1 1 1 0 Phosducin TraF PF13728.1 EME78407.1 - 0.03 13.8 0.0 0.044 13.2 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 EME78407.1 - 0.056 12.9 0.2 0.28 10.6 0.1 1.8 1 1 1 2 2 2 0 Redoxin KilA-N PF04383.8 EME78408.1 - 0.017 14.7 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 KilA-N domain Rho_GDI PF02115.12 EME78409.1 - 5.2e-58 195.7 0.1 5.7e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Fumerase_C PF05683.7 EME78409.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus WD40 PF00400.27 EME78410.1 - 3e-06 26.9 0.0 0.0063 16.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EME78410.1 - 0.0019 17.3 0.0 1.2 8.2 0.0 2.5 2 1 0 2 2 2 2 CPSF A subunit region Apc4_WD40 PF12894.2 EME78410.1 - 0.13 11.7 0.0 33 4.0 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cupin_8 PF13621.1 EME78411.1 - 8.8e-44 149.8 0.0 1.5e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EME78411.1 - 2.6e-20 72.7 0.0 4.4e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EME78411.1 - 4.6e-09 35.8 16.7 0.0026 17.4 0.1 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EME78411.1 - 2.7e-08 33.5 0.0 3.3e-05 23.7 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Cupin_4 PF08007.7 EME78411.1 - 4e-05 23.0 0.0 8.2e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.1 EME78411.1 - 4.5e-05 23.4 9.9 0.28 11.4 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain DSPc PF00782.15 EME78412.1 - 2.3e-29 101.6 0.0 5.5e-21 74.5 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME78412.1 - 2.2e-06 27.2 0.0 0.00048 19.5 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EME78412.1 - 0.034 14.2 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.7 EME78412.1 - 0.06 12.7 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) GATase PF00117.23 EME78413.1 - 1.6e-10 40.7 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EME78413.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pkinase PF00069.20 EME78414.1 - 6.9e-69 231.8 0.0 2e-68 230.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME78414.1 - 3.9e-30 104.7 0.0 3.3e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME78414.1 - 3.9e-06 26.0 0.1 0.056 12.4 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EME78414.1 - 0.018 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME78414.1 - 0.064 12.9 0.0 1 9.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.5 EME78415.1 - 2.9e-27 94.1 0.1 3.3e-27 93.9 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Cep57_MT_bd PF06657.8 EME78415.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EME78416.1 - 0.0022 17.8 1.1 0.0022 17.8 0.7 2.9 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 DUF3417 PF11897.3 EME78416.1 - 0.065 13.1 2.2 0.19 11.6 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) HALZ PF02183.13 EME78416.1 - 2.6 7.8 6.5 0.8 9.4 0.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper SNF2_N PF00176.18 EME78417.1 - 2.9e-61 206.8 0.0 6.4e-61 205.7 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME78417.1 - 3.6e-09 36.3 0.2 2.4e-08 33.7 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EME78417.1 - 1.6e-05 23.8 0.2 6e-05 21.9 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EME78417.1 - 3e-05 23.5 0.0 6.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EME78417.1 - 0.0029 17.2 9.4 0.0029 17.2 6.5 3.2 2 1 1 3 3 3 1 PHD-finger Herpes_BLLF1 PF05109.8 EME78417.1 - 3.9 5.3 5.6 5.5 4.8 3.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Clr2 PF10383.4 EME78418.1 - 1.6e-23 83.2 0.1 5.2e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 DUF4452 PF14618.1 EME78419.1 - 1.2e-49 168.2 9.0 1.5e-49 167.9 6.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) AAA_32 PF13654.1 EME78419.1 - 0.086 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain CITED PF04487.7 EME78419.1 - 5.3 7.2 10.2 0.68 10.1 0.1 2.1 1 1 1 2 2 2 0 CITED GHMP_kinases_N PF00288.21 EME78420.1 - 9.8e-16 57.5 0.8 4.5e-15 55.4 0.3 2.2 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME78420.1 - 9.6e-12 44.9 0.0 2.5e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal PPR_2 PF13041.1 EME78421.1 - 1.3e-42 143.5 12.1 4.7e-09 36.0 0.0 14.1 11 3 6 17 17 17 11 PPR repeat family PPR_3 PF13812.1 EME78421.1 - 7.7e-21 72.5 21.2 0.0069 16.5 0.0 13.8 16 0 0 16 16 16 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME78421.1 - 1.2e-20 72.6 3.7 5.6e-08 32.1 0.0 10.4 11 0 0 11 11 11 3 PPR repeat PPR PF01535.15 EME78421.1 - 4.3e-15 54.5 36.4 0.0018 18.0 0.0 16.2 19 0 0 19 19 19 3 PPR repeat RPM2 PF08579.6 EME78421.1 - 0.00021 21.4 0.0 0.006 16.7 0.0 3.4 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) DUF4511 PF14974.1 EME78421.1 - 0.0078 15.9 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4511) TPR_14 PF13428.1 EME78421.1 - 0.071 13.7 9.1 0.25 12.0 0.2 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_tranf_2_3 PF13641.1 EME78423.1 - 4.8e-39 134.4 0.0 1e-38 133.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME78423.1 - 1.9e-19 70.1 6.6 1.9e-19 70.1 4.6 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EME78423.1 - 8.5e-19 67.8 0.0 1.3e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EME78423.1 - 7.2e-13 48.1 0.0 1.8e-12 46.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EME78423.1 - 2.6e-05 22.7 0.6 0.033 12.5 0.0 2.2 2 0 0 2 2 2 2 Cellulose synthase Chitin_synth_2 PF03142.10 EME78423.1 - 0.0014 17.1 0.1 0.74 8.1 0.0 3.1 3 0 0 3 3 3 1 Chitin synthase Glyco_tranf_2_2 PF10111.4 EME78423.1 - 0.0081 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HTH_1 PF00126.22 EME78424.1 - 0.065 12.9 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Pox_T4_C PF04490.7 EME78424.1 - 0.09 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus KIAA1328 PF15369.1 EME78424.1 - 0.12 12.1 2.9 0.14 11.9 2.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Rpr2 PF04032.11 EME78424.1 - 0.45 10.4 3.7 1.6 8.6 2.6 1.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF678 PF05077.7 EME78424.1 - 3.4 7.7 8.2 4.9 7.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF678) DBR1 PF05011.8 EME78425.1 - 2.3e-40 137.8 0.2 4.3e-40 136.9 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EME78425.1 - 1.8e-07 30.7 0.4 3.2e-07 29.9 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SNARE PF05739.14 EME78426.1 - 4.7e-13 48.6 5.5 4.7e-13 48.6 3.8 2.3 3 0 0 3 3 3 1 SNARE domain Use1 PF09753.4 EME78426.1 - 0.00017 21.0 4.1 0.00022 20.7 1.5 1.9 1 1 1 2 2 2 1 Membrane fusion protein Use1 Cluap1 PF10234.4 EME78426.1 - 0.054 12.6 4.9 0.4 9.8 0.1 2.4 2 1 0 2 2 2 0 Clusterin-associated protein-1 Sec20 PF03908.8 EME78426.1 - 0.074 12.7 0.7 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Sec20 Syntaxin PF00804.20 EME78426.1 - 3.1 8.0 8.5 2.2 8.4 0.3 2.6 2 1 0 2 2 2 0 Syntaxin zf-TRAF PF02176.13 EME78427.1 - 7.7e-12 45.4 19.7 0.0001 22.6 4.5 4.2 1 1 3 4 4 4 4 TRAF-type zinc finger zf-RING_2 PF13639.1 EME78427.1 - 5.7e-09 35.6 12.5 5.7e-09 35.6 8.7 2.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EME78427.1 - 4.3e-08 32.7 4.6 4.3e-08 32.7 3.2 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EME78427.1 - 1.7e-07 30.7 10.2 1.7e-07 30.7 7.1 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME78427.1 - 5.9e-07 29.4 12.2 5.9e-07 29.4 8.5 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME78427.1 - 2.1e-06 27.3 10.4 2.1e-06 27.3 7.2 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EME78427.1 - 2.4e-05 23.7 2.7 2.4e-05 23.7 1.9 2.6 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 EME78427.1 - 8.8e-05 22.1 9.4 8.8e-05 22.1 6.5 3.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME78427.1 - 0.00035 20.3 11.7 0.00035 20.3 8.1 3.5 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EME78427.1 - 0.011 15.7 7.1 0.011 15.7 4.9 3.4 2 2 0 2 2 1 0 RING-H2 zinc finger Sina PF03145.11 EME78427.1 - 0.078 12.6 12.9 0.36 10.4 0.3 3.0 1 1 2 3 3 3 0 Seven in absentia protein family zf-RING_6 PF14835.1 EME78427.1 - 0.58 9.9 16.9 0.64 9.8 8.1 3.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EME78427.1 - 1.4 8.5 21.0 0.054 13.0 2.5 4.8 3 1 2 5 5 5 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EME78427.1 - 7.1 6.5 17.6 0.06 13.1 5.2 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger TRF PF08558.5 EME78428.1 - 7.8e-61 205.4 0.0 1.1e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EME78428.1 - 0.00021 21.3 0.0 0.00055 19.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME78428.1 - 0.027 14.5 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain Acyl_transf_3 PF01757.17 EME78430.1 - 5.6e-27 94.4 33.4 8.6e-27 93.8 23.1 1.3 1 0 0 1 1 1 1 Acyltransferase family SH3_9 PF14604.1 EME78431.1 - 5.6e-07 29.0 0.1 1.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME78431.1 - 3.6e-05 23.0 0.1 8.9e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Aldo_ket_red PF00248.16 EME78432.1 - 8.5e-67 224.9 0.0 9.8e-67 224.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 EME78433.1 - 5.3e-75 252.3 0.0 6.7e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME78433.1 - 5.4e-40 137.0 0.2 8.6e-40 136.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EME78433.1 - 1.6e-06 27.3 0.1 0.00062 18.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME78433.1 - 0.00033 20.6 0.0 0.0017 18.3 0.0 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME78433.1 - 0.0005 19.0 0.0 0.00077 18.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME78433.1 - 0.0039 16.0 0.1 0.016 14.0 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EME78433.1 - 0.0043 17.1 0.0 0.98 9.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME78433.1 - 0.01 15.7 0.1 0.027 14.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME78433.1 - 0.013 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EME78433.1 - 0.017 13.6 0.0 0.031 12.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 EME78433.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DDHD PF02862.12 EME78434.1 - 2.8e-36 125.4 0.0 9e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 DDHD domain Abhydrolase_6 PF12697.2 EME78434.1 - 0.014 15.3 0.0 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME78434.1 - 0.027 14.2 0.0 0.078 12.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Clathrin PF00637.15 EME78435.1 - 1.9e-20 72.8 1.3 2.6e-19 69.2 1.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EME78435.1 - 9.8e-11 41.3 0.0 2.6e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EME78435.1 - 0.0017 18.1 4.0 0.0035 17.1 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain TPR_14 PF13428.1 EME78435.1 - 0.0056 17.2 1.0 3.5 8.5 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME78435.1 - 0.0077 15.8 0.1 0.04 13.5 0.0 2.2 2 0 0 2 2 2 1 TPR repeat zf-C3HC4_2 PF13923.1 EME78435.1 - 0.0091 16.0 3.7 0.017 15.1 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME78435.1 - 0.018 14.7 3.0 0.038 13.7 2.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Utp13 PF08625.6 EME78435.1 - 0.035 13.7 2.1 3.8 7.1 0.1 2.6 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain TPR_2 PF07719.12 EME78435.1 - 0.11 12.5 3.9 0.35 10.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EME78435.1 - 0.23 11.1 3.2 0.47 10.1 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME78435.1 - 0.26 11.4 1.2 0.62 10.2 0.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger MCM_N PF14551.1 EME78435.1 - 0.26 11.7 4.2 1.6 9.2 0.0 3.1 3 1 1 4 4 3 0 MCM N-terminal domain PHD PF00628.24 EME78435.1 - 0.27 10.9 2.2 0.58 9.8 1.5 1.6 1 0 0 1 1 1 0 PHD-finger TPR_1 PF00515.23 EME78435.1 - 2.7 7.7 4.6 5.2 6.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fip1 PF05182.8 EME78436.1 - 8.5e-17 60.1 0.7 1.5e-16 59.3 0.5 1.4 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.7 EME78436.1 - 0.038 12.3 6.8 0.054 11.8 4.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DLIC PF05783.6 EME78436.1 - 2.9 6.4 7.7 0.074 11.7 0.4 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Citrate_synt PF00285.16 EME78439.1 - 2.8e-19 69.0 0.0 1.2e-16 60.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EME78439.1 - 8.3e-17 61.4 0.0 2e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 EME78439.1 - 4e-15 55.7 0.1 8.4e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EME78439.1 - 2.3e-06 27.2 0.0 5.9e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EME78441.1 - 4.9e-07 29.3 0.0 7.6e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain LSM PF01423.17 EME78442.1 - 6.6e-20 70.4 0.2 7.7e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME78442.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain His_Phos_2 PF00328.17 EME78443.1 - 3e-11 43.2 0.1 1.4e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF1897 PF09005.5 EME78444.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) MAPEG PF01124.13 EME78445.1 - 5.4e-11 42.2 2.2 6.5e-11 41.9 1.5 1.1 1 0 0 1 1 1 1 MAPEG family Vmethyltransf_C PF08456.5 EME78446.1 - 0.66 9.3 6.6 0.067 12.5 1.0 2.0 2 0 0 2 2 2 0 Viral methyltransferase C-terminal MFS_1 PF07690.11 EME78447.1 - 3.2e-19 68.8 15.9 4.4e-19 68.3 11.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GDPD PF03009.12 EME78449.1 - 9e-69 231.8 0.0 1.7e-68 230.9 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EME78449.1 - 2.1e-32 111.2 1.6 9.6e-12 45.0 0.1 4.8 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME78449.1 - 2.4e-29 101.1 4.8 8.4e-09 35.7 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 EME78449.1 - 3.8e-29 102.3 7.8 2.9e-18 66.6 2.6 3.3 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EME78449.1 - 2.2e-28 96.5 1.3 1.5e-07 30.8 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EME78449.1 - 4.7e-20 69.6 3.8 8.4e-06 25.5 0.1 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EME78449.1 - 2.2e-19 69.0 0.5 0.00034 20.7 0.0 5.7 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Env-gp36 PF09590.5 EME78449.1 - 0.24 9.5 0.0 0.35 9.0 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein adh_short PF00106.20 EME78450.1 - 1.8e-31 109.2 0.1 2.4e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME78450.1 - 1.9e-21 76.9 0.0 2.6e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME78450.1 - 2.3e-15 56.7 0.0 3.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME78450.1 - 1.9e-07 30.8 0.1 1.3e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME78450.1 - 0.004 15.9 0.1 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME78450.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME78450.1 - 0.04 13.9 0.1 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding PfkB PF00294.19 EME78450.1 - 0.041 13.0 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Eno-Rase_NADH_b PF12242.3 EME78450.1 - 0.057 13.2 0.4 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 EME78450.1 - 0.095 13.2 0.1 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EME78450.1 - 0.14 11.0 0.0 0.3 9.9 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ceramidase PF05875.7 EME78451.1 - 9.9e-62 208.4 8.4 1.1e-61 208.2 5.8 1.0 1 0 0 1 1 1 1 Ceramidase DUF92 PF01940.11 EME78451.1 - 0.021 13.9 0.1 0.05 12.7 0.0 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF92 Bac_small_YrzI PF09501.5 EME78451.1 - 0.11 12.4 2.5 0.33 10.8 1.7 1.7 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DUF202 PF02656.10 EME78451.1 - 1.5 9.1 7.7 15 5.9 0.4 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF202) Methyltransf_24 PF13578.1 EME78452.1 - 2.7e-11 44.2 0.0 3.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EME78452.1 - 0.0036 16.3 0.0 0.0057 15.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EME78452.1 - 0.012 16.1 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4516 PF14990.1 EME78453.1 - 0.19 11.3 2.5 0.66 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) Peroxidase_2 PF01328.12 EME78455.1 - 1.4e-09 37.0 0.1 2.5e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 PEMT PF04191.8 EME78456.1 - 2.5e-53 178.6 11.0 7.4e-35 119.2 1.3 3.8 4 0 0 4 4 4 2 Phospholipid methyltransferase MFS_1 PF07690.11 EME78457.1 - 1.1e-20 73.6 59.8 1.1e-18 67.1 40.1 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily ParA PF10609.4 EME78459.1 - 6.8e-34 115.6 0.1 1.3e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EME78459.1 - 1.1e-14 54.2 0.0 1.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME78459.1 - 5.2e-06 26.4 0.0 3.1e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EME78459.1 - 8.7e-05 21.7 0.6 0.0025 16.8 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EME78459.1 - 0.00021 20.4 0.0 0.00038 19.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EME78459.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME78459.1 - 0.0045 16.2 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EME78459.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_26 PF13500.1 EME78459.1 - 0.031 13.9 0.0 4.4 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME78459.1 - 0.039 13.6 0.1 0.72 9.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EME78459.1 - 0.046 13.8 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EME78459.1 - 0.047 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EME78459.1 - 0.075 12.8 0.1 0.075 12.8 0.1 1.9 3 0 0 3 3 2 0 Transposase zinc-ribbon domain RNA_helicase PF00910.17 EME78459.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase VirE PF05272.6 EME78459.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Glyco_hydro_43 PF04616.9 EME78460.1 - 1.1e-17 64.0 0.2 1.7e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_S10 PF00450.17 EME78461.1 - 5.8e-77 259.6 0.1 7.7e-77 259.1 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RelB_N PF12910.2 EME78461.1 - 0.033 13.5 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal zf-C2H2_2 PF12756.2 EME78462.1 - 1.3e-22 79.7 7.1 5.4e-20 71.3 3.5 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EME78462.1 - 0.011 16.0 0.8 0.011 16.0 0.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME78462.1 - 0.077 13.3 10.8 0.82 10.1 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME78462.1 - 0.52 10.5 5.8 1.6 8.9 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mannosyl_trans3 PF11051.3 EME78464.1 - 0.00015 21.2 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EME78464.1 - 0.0004 19.8 0.1 0.0011 18.3 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 CDC27 PF09507.5 EME78465.1 - 2.5e-90 303.7 28.3 3e-90 303.5 19.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Fe_dep_repress PF01325.14 EME78465.1 - 0.015 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Thioesterase PF00975.15 EME78466.1 - 5.6e-26 92.1 0.0 1.2e-25 91.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EME78466.1 - 5e-05 23.2 0.0 0.00027 20.9 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME78466.1 - 0.04 13.6 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 EME78468.1 - 8.1e-72 242.2 26.7 9.3e-72 242.0 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78468.1 - 1.4e-22 79.8 37.7 6.8e-13 48.0 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EME78469.1 - 4.5e-17 61.7 0.2 7.2e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VSP PF03302.8 EME78470.1 - 0.01 14.5 2.1 0.015 13.9 1.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.5 EME78470.1 - 5.7 6.3 10.0 16 4.9 6.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EME78470.1 - 9.5 5.8 7.6 0.46 10.0 1.2 1.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 MFS_1 PF07690.11 EME78471.1 - 6.7e-26 90.8 28.9 6.7e-26 90.8 20.0 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.22 EME78472.1 - 1e-14 54.6 4.6 1.3e-14 54.2 3.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME78472.1 - 0.0016 17.9 1.6 0.0028 17.2 1.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAP_C PF03943.8 EME78472.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 TAP C-terminal domain PEX11 PF05648.9 EME78474.1 - 1.3e-33 116.1 0.0 1.5e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MFS_1 PF07690.11 EME78475.1 - 1.5e-32 112.6 31.2 2.3e-32 112.1 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EME78475.1 - 0.023 15.0 0.1 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1228 PF06779.9 EME78475.1 - 0.087 12.8 0.4 0.087 12.8 0.3 3.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1228) COesterase PF00135.23 EME78476.1 - 3e-108 362.8 0.0 4e-108 362.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME78476.1 - 3.5e-09 36.5 0.0 7.9e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78476.1 - 0.0065 16.2 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 EME78477.1 - 2.9e-10 40.7 0.0 4.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME78477.1 - 1.4e-08 34.1 0.0 2.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME78477.1 - 8.7e-08 32.5 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME78477.1 - 1.4e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME78477.1 - 1.8e-06 27.8 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME78477.1 - 4.4e-06 26.9 0.0 1.3e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME78477.1 - 1.3e-05 25.5 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME78477.1 - 2.5e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EME78477.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Rsm22 PF09243.5 EME78477.1 - 0.049 12.6 0.0 0.086 11.8 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DUF43 PF01861.11 EME78477.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 DUF998 PF06197.8 EME78478.1 - 1.9e-05 24.0 14.6 1.9e-05 24.0 10.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF998) Frag1 PF10277.4 EME78478.1 - 0.019 14.4 3.1 0.24 10.8 2.2 2.2 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family MnhB PF04039.8 EME78478.1 - 0.051 13.6 3.4 0.22 11.5 1.4 2.4 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter NADH-u_ox-rdase PF10785.4 EME78478.1 - 0.69 10.1 2.7 3.7 7.8 0.2 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit AA_permease PF00324.16 EME78479.1 - 1.3e-113 379.8 40.2 1.6e-113 379.5 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME78479.1 - 5.1e-32 110.9 39.4 6.8e-32 110.5 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1612 PF07756.7 EME78479.1 - 0.056 13.5 0.6 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) LRR_4 PF12799.2 EME78481.1 - 7.2e-23 79.7 35.3 2e-06 27.2 3.2 8.6 3 3 8 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME78481.1 - 1.2e-18 66.5 32.3 0.0002 21.0 1.6 6.7 4 1 2 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EME78481.1 - 1.8e-11 42.3 39.3 0.71 10.1 0.1 13.5 12 3 1 13 13 13 5 Leucine Rich Repeat LRR_6 PF13516.1 EME78481.1 - 2.3e-05 24.0 29.7 1.2 9.4 0.2 10.2 9 2 2 11 11 11 3 Leucine Rich repeat LRR_7 PF13504.1 EME78481.1 - 2.5e-05 23.7 42.9 6.1 7.5 0.0 13.3 16 0 0 16 16 16 2 Leucine rich repeat LRR_9 PF14580.1 EME78481.1 - 0.019 14.5 8.2 0.13 11.8 0.1 3.9 1 1 3 4 4 4 0 Leucine-rich repeat LRR_2 PF07723.8 EME78481.1 - 0.49 10.9 3.9 11 6.7 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat zf-H2C2_2 PF13465.1 EME78487.1 - 0.11 12.8 0.3 0.11 12.8 0.2 3.7 3 1 0 3 3 3 0 Zinc-finger double domain zf-RING_3 PF14369.1 EME78487.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.1 3 0 0 3 3 3 0 zinc-finger FYVE PF01363.16 EME78487.1 - 0.79 9.6 30.0 12 5.9 12.9 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C3HC4 PF00097.20 EME78487.1 - 0.89 9.2 25.5 0.22 11.1 4.5 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) APT PF03440.9 EME78487.1 - 1.1 9.0 3.3 14 5.4 0.2 2.9 2 1 1 3 3 3 0 Aerolysin/Pertussis toxin (APT) domain Siva PF05458.7 EME78487.1 - 3.2 7.2 14.8 1.8 8.0 2.8 2.1 1 1 1 2 2 2 0 Cd27 binding protein (Siva) Prok-RING_2 PF14445.1 EME78487.1 - 3.9 7.5 14.1 1.6 8.6 2.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 RPAP2_Rtr1 PF04181.8 EME78487.1 - 5.5 7.1 16.7 14 5.8 2.3 2.3 1 1 1 2 2 2 0 Rtr1/RPAP2 family RNA_pol PF00940.14 EME78488.1 - 6.1e-158 525.5 0.0 8.3e-158 525.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EME78488.1 - 6.9e-59 199.6 3.0 6.9e-59 199.6 2.1 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DUF221 PF02714.10 EME78489.1 - 9.2e-111 369.8 17.8 9.2e-111 369.8 12.4 2.3 4 0 0 4 4 4 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME78489.1 - 9.9e-39 132.4 2.0 9.9e-39 132.4 1.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EME78489.1 - 7.7e-30 102.6 0.1 1.6e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EME78489.1 - 2.3e-22 79.3 2.7 4e-22 78.5 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EME78489.1 - 0.0014 18.5 0.1 0.017 15.0 0.1 2.5 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78489.1 - 0.016 15.0 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME78489.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3377 PF11857.3 EME78489.1 - 0.05 13.2 0.0 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DDE_Tnp_4 PF13359.1 EME78491.1 - 0.00052 19.6 0.0 0.00054 19.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Thr_synth_N PF14821.1 EME78492.1 - 1.5e-29 101.8 0.0 3e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EME78492.1 - 1.1e-19 70.7 0.0 1.5e-18 67.0 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3213 PF11491.3 EME78494.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Cpn10 PF00166.16 EME78496.1 - 5e-29 100.0 0.0 5.6e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit WD40 PF00400.27 EME78497.1 - 1.9e-08 33.8 2.2 0.28 11.1 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.4 EME78497.1 - 8.5e-05 21.7 0.0 0.00031 19.9 0.0 1.8 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EME78497.1 - 0.0047 15.2 0.0 0.007 14.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain SGL PF08450.7 EME78497.1 - 0.014 14.8 0.0 0.068 12.5 0.0 1.9 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region TSKS PF15358.1 EME78498.1 - 0.0072 14.5 0.1 0.009 14.2 0.1 1.1 1 0 0 1 1 1 1 Testis-specific serine kinase substrate F-box-like_2 PF13013.1 EME78498.1 - 0.058 13.1 0.1 0.091 12.4 0.0 1.4 1 1 0 1 1 1 0 F-box-like domain DUF3848 PF12959.2 EME78498.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) PBP PF01161.15 EME78499.1 - 4.7e-14 52.4 0.1 6.6e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Cytomega_UL20A PF05984.7 EME78499.1 - 0.097 12.8 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Spc97_Spc98 PF04130.8 EME78501.1 - 4.7e-71 239.7 0.4 6.3e-71 239.3 0.3 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family zf-ZPR1 PF03367.8 EME78502.1 - 2.8e-105 348.4 0.3 6.6e-52 174.9 0.0 2.5 2 1 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.5 EME78502.1 - 2.1 8.3 8.2 8.9 6.3 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain NACHT PF05729.7 EME78504.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_43 PF04616.9 EME78507.1 - 2.7e-60 203.8 19.1 4.3e-50 170.4 3.2 2.5 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EME78507.1 - 4.9e-09 35.9 4.7 1.1e-06 28.3 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Cu-oxidase_3 PF07732.10 EME78508.1 - 7.5e-34 115.9 3.6 1.3e-30 105.5 1.2 3.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME78508.1 - 6.8e-27 93.6 7.6 1.6e-25 89.2 0.8 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EME78508.1 - 1.5e-15 57.4 0.0 1.5e-14 54.1 0.0 2.6 2 1 0 2 2 2 1 Multicopper oxidase HgmA PF04209.8 EME78509.1 - 3.4e-137 457.2 0.0 3.9e-137 457.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Transp_cyt_pur PF02133.10 EME78510.1 - 4.9e-35 120.9 31.8 4.7e-34 117.7 22.1 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Microcin PF03526.8 EME78510.1 - 0.038 13.5 0.2 0.13 11.8 0.1 2.0 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Abhydrolase_3 PF07859.8 EME78511.1 - 2.8e-58 196.9 0.0 3.5e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME78511.1 - 1.6e-09 37.0 0.0 4.4e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EME78511.1 - 3.2e-05 23.2 0.0 0.00047 19.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EME78511.1 - 0.00026 19.7 0.0 0.00039 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EME78511.1 - 0.00051 19.8 0.0 0.0008 19.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME78511.1 - 0.0011 18.3 0.0 0.9 8.7 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 EME78511.1 - 0.0036 16.7 0.0 0.13 11.7 0.0 2.4 3 0 0 3 3 3 1 Putative esterase Chlorophyllase2 PF12740.2 EME78511.1 - 0.021 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme ECH PF00378.15 EME78512.1 - 1.5e-46 158.5 0.5 2e-45 154.8 0.4 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EME78512.1 - 0.00025 20.8 0.2 0.003 17.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 DEAD PF00270.24 EME78514.1 - 1.5e-42 144.9 0.0 3.3e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EME78514.1 - 3.4e-22 77.7 0.3 9.5e-22 76.3 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EME78514.1 - 1.3e-20 73.0 0.0 3.3e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EME78514.1 - 0.0065 16.4 0.1 0.018 14.9 0.1 1.8 1 1 0 1 1 1 1 Helicase C-terminal domain DnaJ PF00226.26 EME78515.1 - 4.6e-16 58.3 1.8 4.6e-16 58.3 1.2 2.3 3 0 0 3 3 3 1 DnaJ domain Toprim_3 PF13362.1 EME78515.1 - 0.38 11.0 5.9 1.9 8.8 1.1 2.6 1 1 2 3 3 3 0 Toprim domain Transformer PF06495.6 EME78515.1 - 3.2 7.5 8.8 5.3 6.8 6.1 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein M PF02370.11 EME78518.1 - 1.3 9.5 4.9 8.5 7.1 0.5 2.8 2 0 0 2 2 2 0 M protein repeat DUF1762 PF08574.5 EME78519.1 - 0.15 12.5 0.1 0.41 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) Met_10 PF02475.11 EME78520.1 - 5e-05 22.9 0.0 7.2e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Sugar_tr PF00083.19 EME78522.1 - 1e-86 291.3 27.4 1.2e-86 291.0 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78522.1 - 1.4e-25 89.7 34.4 6.7e-24 84.2 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EME78522.1 - 3.9 7.6 7.4 0.7 10.0 1.7 2.3 2 0 0 2 2 2 0 Phage holin family 2 Kinesin PF00225.18 EME78523.1 - 4.5e-91 305.0 0.0 4.5e-91 305.0 0.0 3.3 3 0 0 3 3 3 1 Kinesin motor domain DUF869 PF05911.6 EME78523.1 - 8.8 4.4 116.9 0.048 11.9 14.3 5.3 3 1 1 5 5 5 0 Plant protein of unknown function (DUF869) HET PF06985.6 EME78526.1 - 1.1e-29 103.4 0.1 1.4e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MT-A70 PF05063.9 EME78527.1 - 5.5e-32 110.7 0.2 7.9e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.10 EME78527.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Mito_carr PF00153.22 EME78528.1 - 3.6e-59 196.4 5.2 1.2e-19 69.8 0.0 4.5 4 1 1 5 5 5 4 Mitochondrial carrier protein AIRS PF00586.19 EME78528.1 - 0.098 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain DUF3463 PF11946.3 EME78530.1 - 0.026 14.1 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) WD40 PF00400.27 EME78532.1 - 0.065 13.1 0.2 1.7 8.6 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Smg4_UPF3 PF03467.10 EME78533.1 - 3.7e-22 79.1 0.7 9.6e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_6 PF14259.1 EME78533.1 - 0.0014 18.5 0.0 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME78533.1 - 0.0039 16.7 0.0 0.014 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78533.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 EME78533.1 - 0.5 9.7 29.0 0.76 9.1 20.1 1.2 1 0 0 1 1 1 0 Vta1 like Amidoligase_2 PF12224.3 EME78534.1 - 5.2e-17 62.3 0.0 4.3e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Peptidase_C48 PF02902.14 EME78537.1 - 6.2e-15 55.4 0.0 7.6e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TRI12 PF06609.8 EME78538.1 - 1.3e-30 106.1 24.1 1.7e-30 105.8 16.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME78538.1 - 1.7e-18 66.4 49.6 1.7e-18 66.4 34.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME78538.1 - 9.3e-09 34.3 15.4 9.3e-09 34.3 10.7 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter ComFB PF10719.4 EME78539.1 - 0.09 12.5 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Late competence development protein ComFB AA_permease PF00324.16 EME78540.1 - 1.7e-134 448.7 39.3 1.9e-134 448.5 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME78540.1 - 6.4e-35 120.5 42.5 8e-35 120.1 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF202 PF02656.10 EME78541.1 - 1.6e-20 73.0 0.1 1.6e-20 73.0 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 EME78541.1 - 0.034 14.1 2.3 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV EI24 PF07264.6 EME78541.1 - 0.26 10.6 3.9 0.19 11.1 1.5 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) 2TM PF13239.1 EME78541.1 - 0.34 11.0 2.1 0.31 11.1 0.2 1.8 1 1 1 2 2 2 0 2TM domain DUF3112 PF11309.3 EME78541.1 - 0.94 9.2 5.3 17 5.1 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF3592 PF12158.3 EME78541.1 - 2.9 7.6 4.7 4.7 6.9 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) adh_short PF00106.20 EME78542.1 - 2.8e-13 50.1 0.0 1.5e-12 47.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME78542.1 - 5.2e-06 26.2 0.0 8.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EME78542.1 - 0.0037 16.2 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EME78542.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME78542.1 - 0.1 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding DEAD PF00270.24 EME78543.1 - 1.1e-45 155.1 0.0 3.3e-45 153.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EME78543.1 - 1.4e-21 76.0 6.8 1.4e-21 76.0 4.7 2.0 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EME78543.1 - 2e-21 75.6 0.0 6.8e-21 73.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RPA_C PF08784.6 EME78544.1 - 2.7e-16 59.8 0.8 4.9e-16 59.0 0.5 1.4 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EME78544.1 - 1.4e-07 31.2 0.1 2.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_20 PF12840.2 EME78544.1 - 0.12 12.1 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PRMT5 PF05185.11 EME78545.1 - 2.3e-162 540.9 0.0 2.7e-162 540.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF3070 PF11270.3 EME78545.1 - 0.021 14.5 3.1 0.07 12.9 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) Ank_2 PF12796.2 EME78546.1 - 3.8e-70 232.2 8.6 1.3e-13 51.0 0.0 7.1 4 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EME78546.1 - 2.7e-44 146.8 15.2 6.3e-05 22.5 0.0 14.7 15 0 0 15 15 15 9 Ankyrin repeat Ank_4 PF13637.1 EME78546.1 - 5.9e-41 138.1 11.4 1.5e-07 31.7 0.0 11.0 6 4 6 13 13 13 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME78546.1 - 6.3e-35 118.4 18.4 2.7e-05 24.2 0.3 10.4 8 3 3 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME78546.1 - 1.6e-32 108.3 15.5 0.00055 19.9 0.1 14.2 16 0 0 16 16 16 8 Ankyrin repeat FSH1 PF03959.8 EME78547.1 - 5e-52 176.4 0.0 5.8e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EME78547.1 - 1.5e-06 27.8 0.2 0.31 10.4 0.5 3.1 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EME78547.1 - 2e-06 27.8 0.3 0.014 15.3 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME78547.1 - 3.1e-06 27.0 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78547.1 - 0.0006 19.4 0.5 0.004 16.7 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hamartin PF04388.7 EME78548.1 - 5.4e-46 157.5 5.6 2e-45 155.6 3.9 1.8 1 1 0 1 1 1 1 Hamartin protein DUF972 PF06156.8 EME78548.1 - 0.58 10.5 0.0 0.58 10.5 0.0 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF972) WEMBL PF05701.6 EME78548.1 - 0.94 7.8 36.2 0.6 8.4 12.2 2.7 1 1 2 3 3 3 0 Weak chloroplast movement under blue light F-box PF00646.28 EME78549.1 - 0.15 11.7 0.8 0.42 10.3 0.1 2.1 2 1 0 2 2 2 0 F-box domain AAA_12 PF13087.1 EME78551.1 - 3.4e-41 140.8 0.0 6.1e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME78551.1 - 1.6e-28 99.9 0.1 3.9e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME78551.1 - 1.3e-10 40.9 0.0 5.3e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EME78551.1 - 9.9e-08 31.7 0.1 0.00016 21.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EME78551.1 - 1.4e-05 24.3 0.1 0.033 13.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EME78551.1 - 0.0015 17.8 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EME78551.1 - 0.0071 16.1 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 EME78551.1 - 0.0073 16.4 0.0 0.025 14.6 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EME78551.1 - 0.01 15.1 0.0 0.077 12.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EME78551.1 - 0.036 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME78551.1 - 0.044 13.9 0.2 0.58 10.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Glutaminase PF04960.10 EME78552.1 - 8.6e-100 333.4 0.1 1.2e-99 332.9 0.1 1.2 1 0 0 1 1 1 1 Glutaminase Pyridox_oxidase PF01243.15 EME78553.1 - 8.9e-10 38.4 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-HIT PF04438.11 EME78554.1 - 1.8e-08 33.8 12.9 2.8e-08 33.2 9.0 1.3 1 0 0 1 1 1 1 HIT zinc finger DENN PF02141.16 EME78555.1 - 5.5e-40 137.0 0.1 9.4e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EME78555.1 - 0.00065 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EME78555.1 - 0.0067 16.7 5.3 0.0067 16.7 3.7 2.0 1 1 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-F_leu_zip PF10473.4 EME78555.1 - 1.5 8.7 18.3 0.015 15.1 4.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2570 PF10828.3 EME78555.1 - 4.8 6.8 9.6 3.9 7.1 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) zf-RING_5 PF14634.1 EME78556.1 - 1.8e-07 30.7 7.1 2.8e-07 30.1 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME78556.1 - 2.8e-05 24.0 3.5 5.3e-05 23.1 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME78556.1 - 0.00057 19.4 5.6 0.00099 18.7 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME78556.1 - 0.0018 17.9 6.0 0.0031 17.1 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME78556.1 - 0.004 16.9 1.9 0.0082 15.9 1.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EME78556.1 - 0.0043 16.8 7.0 0.0074 16.0 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EME78556.1 - 0.044 13.3 2.2 0.078 12.5 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1664 PF07889.7 EME78556.1 - 0.046 13.5 2.3 0.074 12.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.6 EME78556.1 - 0.074 11.7 5.6 0.1 11.2 3.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) RNA_lig_T4_1 PF09511.5 EME78556.1 - 0.18 11.2 1.2 0.3 10.5 0.6 1.3 1 1 0 1 1 1 0 RNA ligase zf-RING_UBOX PF13445.1 EME78556.1 - 0.19 11.4 2.7 0.4 10.4 1.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 EME78556.1 - 0.24 11.2 2.9 0.54 10.1 2.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon V_ATPase_I PF01496.14 EME78556.1 - 0.48 8.2 4.8 0.6 7.9 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRF PF08558.5 EME78556.1 - 0.5 9.6 4.3 1.3 8.3 0.2 2.3 1 1 1 2 2 2 0 Telomere repeat binding factor (TRF) DUF972 PF06156.8 EME78556.1 - 0.73 10.2 4.8 1.4 9.3 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 EME78556.1 - 1.2 9.2 14.9 0.35 10.9 7.5 2.0 1 1 1 2 2 2 0 DivIVA protein APG6 PF04111.7 EME78556.1 - 1.5 7.8 12.1 2.1 7.3 8.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Sugar_tr PF00083.19 EME78558.1 - 5.3e-41 140.6 32.8 1.9e-38 132.2 22.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78558.1 - 5.7e-24 84.4 37.5 1.5e-14 53.5 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 EME78558.1 - 3.3 6.7 6.2 6.2 5.9 0.5 3.5 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Clr5 PF14420.1 EME78559.1 - 1.7e-07 31.0 3.5 2.2e-07 30.6 0.7 2.3 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.1 EME78559.1 - 0.079 12.9 0.6 14 5.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Skp1_POZ PF03931.10 EME78560.1 - 9.9e-08 31.9 0.0 2.4e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain SGL PF08450.7 EME78560.1 - 0.0065 15.8 0.0 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Phosphoesterase PF04185.9 EME78561.1 - 1.6e-12 47.3 0.2 3.3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Phosphoesterase family Fascin PF06268.8 EME78561.1 - 0.066 13.3 0.0 0.37 10.9 0.0 2.2 1 1 0 1 1 1 0 Fascin domain FGF PF00167.13 EME78561.1 - 0.1 12.3 0.0 0.37 10.5 0.0 1.8 1 1 1 2 2 2 0 Fibroblast growth factor Cu-oxidase_3 PF07732.10 EME78562.1 - 8.5e-41 138.3 9.2 5.6e-40 135.7 0.2 4.2 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME78562.1 - 1.1e-31 109.1 10.5 9.6e-30 102.8 1.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EME78562.1 - 8.8e-14 51.7 0.0 6.2e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Pyr_redox_3 PF13738.1 EME78563.1 - 3.2e-19 69.7 0.0 5.5e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME78563.1 - 1.5e-09 36.5 0.0 2.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME78563.1 - 1.1e-08 34.9 0.0 8.6e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME78563.1 - 1.8e-06 28.0 0.0 0.051 13.4 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME78563.1 - 3.9e-06 26.0 0.0 4.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EME78563.1 - 8.5e-05 22.8 0.0 0.0095 16.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME78563.1 - 0.00018 20.5 0.0 0.0017 17.3 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EME78563.1 - 0.0038 17.4 0.0 0.11 12.7 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EME78563.1 - 0.0048 16.6 0.0 0.34 10.6 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EME78563.1 - 0.0073 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EME78563.1 - 0.038 13.0 0.1 0.35 9.9 0.0 2.3 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.15 EME78563.1 - 0.054 13.6 0.0 4.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF1965 PF09248.5 EME78564.1 - 2.8e-07 30.3 0.1 7.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) UMP1 PF05348.6 EME78566.1 - 6e-28 97.4 0.0 7.4e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 EME78567.1 - 9.2e-11 41.6 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME78567.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EME78567.1 - 0.0082 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain NMD3 PF04981.8 EME78568.1 - 3.4e-71 239.0 1.0 5.3e-71 238.4 0.7 1.3 1 0 0 1 1 1 1 NMD3 family Nif11 PF07862.6 EME78568.1 - 0.029 14.3 0.1 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function DZR PF12773.2 EME78568.1 - 0.11 12.2 5.8 1.1 9.0 2.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EME78568.1 - 0.25 11.0 2.5 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4200 PF13863.1 EME78568.1 - 0.49 10.3 11.0 3.7 7.4 6.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-C4pol PF14260.1 EME78568.1 - 0.51 10.3 3.9 4.7 7.2 0.5 3.0 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta FYVE PF01363.16 EME78568.1 - 0.61 10.0 4.3 2.2 8.2 0.7 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF35_N PF12172.3 EME78568.1 - 2.7 8.0 5.8 0.65 9.9 0.1 2.7 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DHC_N1 PF08385.7 EME78569.1 - 3.6e-165 550.6 2.2 3.6e-165 550.6 1.5 5.0 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EME78569.1 - 4.1e-133 443.8 5.2 4.1e-133 443.8 3.6 5.0 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EME78569.1 - 2.6e-103 346.4 0.2 9.2e-103 344.6 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EME78569.1 - 6e-77 258.2 0.0 1.7e-76 256.7 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EME78569.1 - 4.4e-42 143.9 0.0 2.2e-41 141.6 0.0 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EME78569.1 - 8.5e-41 139.2 0.0 5.3e-40 136.6 0.0 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 EME78569.1 - 4e-38 131.0 7.6 9.2e-38 129.8 5.3 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EME78569.1 - 7.4e-29 100.2 0.0 7.3e-12 45.2 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EME78569.1 - 3.6e-19 68.9 0.2 1e-17 64.1 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EME78569.1 - 8.9e-16 58.2 0.0 0.011 15.9 0.0 6.5 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 EME78569.1 - 2.4e-13 50.4 0.0 0.0052 16.9 0.0 5.3 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EME78569.1 - 4e-11 42.9 0.2 0.034 14.0 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EME78569.1 - 1.6e-09 38.6 0.2 0.071 13.9 0.0 6.3 5 0 0 5 5 5 1 AAA domain T2SE PF00437.15 EME78569.1 - 2e-09 36.7 0.0 0.015 14.1 0.0 4.0 4 0 0 4 4 4 3 Type II/IV secretion system protein AAA_18 PF13238.1 EME78569.1 - 2.2e-08 34.4 0.1 0.04 14.2 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.1 EME78569.1 - 9.9e-07 28.7 0.0 0.6 10.0 0.0 5.2 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 EME78569.1 - 2.5e-06 27.1 0.0 0.36 10.2 0.1 4.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EME78569.1 - 3.2e-06 26.5 0.1 0.63 9.6 0.1 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 EME78569.1 - 3.3e-06 26.7 0.6 1.1 9.1 0.0 4.8 4 0 0 4 4 4 1 Part of AAA domain AAA_16 PF13191.1 EME78569.1 - 4.6e-06 26.7 21.0 0.15 12.0 0.1 8.6 7 1 1 8 8 7 2 AAA ATPase domain ABC_tran PF00005.22 EME78569.1 - 3e-05 24.3 0.1 4.4 7.6 0.0 5.2 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 EME78569.1 - 3.4e-05 23.0 1.0 0.46 9.5 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EME78569.1 - 0.00037 19.9 2.1 1.7 8.0 0.0 5.1 5 0 0 5 5 5 1 AAA domain RNA_helicase PF00910.17 EME78569.1 - 0.0016 18.5 0.2 3.3 7.9 0.0 4.4 4 0 0 4 4 4 1 RNA helicase DUF258 PF03193.11 EME78569.1 - 0.005 16.0 0.1 4.8 6.3 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function, DUF258 MobB PF03205.9 EME78569.1 - 0.012 15.3 0.7 10 5.8 0.1 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EME78569.1 - 0.049 13.1 0.6 7.3 6.0 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EME78569.1 - 3.1 8.0 30.9 3.3 8.0 0.2 7.9 8 0 0 8 8 7 0 AAA domain Pkinase PF00069.20 EME78570.1 - 9.6e-64 215.0 0.0 1.7e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME78570.1 - 6.5e-36 123.7 0.0 1.1e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EME78570.1 - 1.7e-28 98.1 13.4 3.7e-15 55.4 2.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EME78570.1 - 1.6e-20 72.5 30.3 1.9e-11 43.5 6.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EME78570.1 - 2.9e-13 50.1 1.9 9.8e-13 48.4 1.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EME78570.1 - 0.026 13.4 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Acetyltransf_9 PF13527.1 EME78571.1 - 0.029 14.2 0.0 0.082 12.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DXP_reductoisom PF02670.11 EME78572.1 - 0.0014 19.2 0.4 0.0047 17.4 0.3 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase zf-C3HC4_2 PF13923.1 EME78572.1 - 2.6 8.1 22.0 0.28 11.2 5.4 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Acyl_transf_3 PF01757.17 EME78573.1 - 1.3e-18 66.9 36.1 2.1e-18 66.3 25.0 1.3 1 0 0 1 1 1 1 Acyltransferase family Asp PF00026.18 EME78574.1 - 6.3e-70 235.9 1.7 8.2e-70 235.5 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EME78574.1 - 0.0054 17.2 1.7 0.28 11.7 0.1 3.4 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EME78574.1 - 0.13 11.8 0.0 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal ADH_N PF08240.7 EME78575.1 - 1.2e-29 102.2 0.5 2.3e-29 101.3 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME78575.1 - 2.1e-23 82.2 0.1 2.1e-23 82.2 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME78575.1 - 0.0016 19.3 0.1 0.0031 18.3 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME78575.1 - 0.0028 16.8 0.1 0.0049 16.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME78575.1 - 0.045 13.3 0.3 0.072 12.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EME78575.1 - 0.051 13.4 0.7 0.094 12.6 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Lon_C PF05362.8 EME78578.1 - 1.1e-68 230.6 0.2 2e-68 229.7 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EME78578.1 - 1.3e-28 100.0 1.3 1.7e-28 99.7 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EME78578.1 - 1.5e-23 83.4 0.0 6.4e-23 81.3 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME78578.1 - 4.8e-09 36.0 0.0 1.9e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EME78578.1 - 3.8e-08 32.8 0.0 1.1e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EME78578.1 - 1.3e-06 28.4 0.7 2.2e-05 24.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EME78578.1 - 7.3e-06 25.9 0.0 2.5e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EME78578.1 - 1.1e-05 26.2 0.0 6.4e-05 23.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME78578.1 - 1.6e-05 24.3 0.0 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EME78578.1 - 2.9e-05 23.6 0.0 9.4e-05 22.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EME78578.1 - 4e-05 22.5 0.2 0.00023 20.0 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EME78578.1 - 8.7e-05 21.6 0.1 0.0012 17.9 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME78578.1 - 0.00011 22.2 0.1 0.0051 16.9 0.0 3.6 3 1 1 4 4 3 1 AAA domain AAA_14 PF13173.1 EME78578.1 - 0.00094 19.0 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME78578.1 - 0.001 18.9 0.4 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME78578.1 - 0.0013 18.4 0.6 0.0076 15.9 0.0 2.6 3 0 0 3 3 1 1 Part of AAA domain Zeta_toxin PF06414.7 EME78578.1 - 0.0086 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EME78578.1 - 0.0099 15.5 0.0 0.069 12.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EME78578.1 - 0.01 15.2 0.0 0.033 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EME78578.1 - 0.017 14.3 0.0 0.072 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME78578.1 - 0.017 15.4 7.3 0.024 14.9 0.0 2.7 1 1 1 2 2 1 0 AAA domain AAA_24 PF13479.1 EME78578.1 - 0.017 14.6 0.2 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME78578.1 - 0.018 15.3 0.0 0.059 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EME78578.1 - 0.02 14.6 0.1 0.17 11.6 0.0 2.5 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EME78578.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EME78578.1 - 0.04 13.0 0.1 0.11 11.6 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 EME78578.1 - 0.046 12.5 0.0 0.089 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EME78578.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EME78578.1 - 0.052 13.2 0.0 0.22 11.1 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EME78578.1 - 0.055 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EME78578.1 - 0.056 12.2 3.3 7 5.3 0.0 3.7 4 0 0 4 4 4 0 ArgK protein AAA_PrkA PF08298.6 EME78578.1 - 0.13 10.8 0.8 1.5 7.3 0.1 2.4 2 1 0 2 2 2 0 PrkA AAA domain AAA_10 PF12846.2 EME78578.1 - 0.24 10.7 1.4 0.95 8.8 0.0 2.4 2 1 1 3 3 3 0 AAA-like domain Glyco_transf_17 PF04724.8 EME78581.1 - 5.1e-49 167.1 0.1 1.4e-48 165.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 17 RRM_1 PF00076.17 EME78582.1 - 1e-13 50.6 0.0 1.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME78582.1 - 4e-11 42.7 0.0 6.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EME78582.1 - 0.00025 21.4 4.3 0.00025 21.4 3.0 3.2 2 2 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EME78582.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.17 EME78583.1 - 4.6e-188 625.2 1.0 5.2e-188 625.0 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME78583.1 - 0.02 14.1 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF924 PF06041.6 EME78584.1 - 1.1e-38 132.8 0.0 1.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PHBC_N PF12551.3 EME78584.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal WD40 PF00400.27 EME78585.1 - 0.019 14.8 0.7 0.51 10.3 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribonuclease_3 PF00636.21 EME78586.1 - 1.5e-22 80.2 0.1 1.9e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EME78586.1 - 2.2e-16 59.9 0.2 2.5e-16 59.7 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease-III-like MRP-S33 PF08293.6 EME78587.1 - 3.4e-25 87.8 0.1 3.8e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 F-box-like_2 PF13013.1 EME78588.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.4 1 1 0 1 1 1 0 F-box-like domain Antigen_Bd37 PF11641.3 EME78590.1 - 2.3 7.4 6.0 1.5 8.0 3.0 1.5 1 1 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein TP53IP5 PF15331.1 EME78590.1 - 6.8 6.5 9.6 8.5 6.2 6.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Cytomega_UL84 PF06284.6 EME78590.1 - 7.5 4.8 5.8 9.3 4.5 4.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein GATase PF00117.23 EME78591.1 - 2.4e-37 128.2 0.0 4e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EME78591.1 - 3.3e-27 94.0 0.0 7e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EME78591.1 - 2.1e-10 39.8 0.1 3.7e-06 26.0 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EME78591.1 - 2e-06 27.4 0.0 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EME78591.1 - 0.00046 18.8 0.1 0.0012 17.4 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EME78591.1 - 0.0019 17.6 0.0 0.0066 15.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 EME78591.1 - 0.0036 16.6 0.1 0.026 13.8 0.0 2.3 2 1 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EME78591.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Arginosuc_synth PF00764.14 EME78591.1 - 0.018 14.0 0.1 0.034 13.1 0.1 1.4 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 EME78591.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family DUF2392 PF10288.4 EME78591.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) BCIP PF13862.1 EME78592.1 - 1.4e-69 233.5 0.6 1.8e-69 233.1 0.4 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Abhydrolase_5 PF12695.2 EME78593.1 - 3.4e-11 43.0 0.0 5.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EME78593.1 - 8.9e-10 37.4 0.0 0.00023 19.5 0.0 2.6 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EME78593.1 - 1e-06 28.8 0.3 1.5e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EME78593.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) BAAT_C PF08840.6 EME78593.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal NAD_binding_2 PF03446.10 EME78594.1 - 1.3e-37 129.1 0.0 1.9e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME78594.1 - 4.1e-28 97.8 0.1 7.5e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EME78594.1 - 0.0015 18.9 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EME78594.1 - 0.0022 16.8 0.0 0.0045 15.8 0.0 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EME78594.1 - 0.086 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF970 PF06153.6 EME78594.1 - 0.093 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF970) DUF4215 PF13948.1 EME78595.1 - 0.2 11.8 7.6 3.9 7.7 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) zf-C3HC4_3 PF13920.1 EME78595.1 - 0.74 9.5 8.3 0.26 10.9 2.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EME78595.1 - 9.4 6.3 7.8 3.9 7.5 0.1 2.9 2 1 0 2 2 2 0 zinc-finger zf-C3HC4_2 PF13923.1 EME78595.1 - 9.6 6.3 9.0 27 4.9 2.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME78596.1 - 2.1e-09 36.8 10.5 4.4e-09 35.8 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME78596.1 - 3.3e-09 36.3 10.7 3.3e-09 36.3 7.4 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME78596.1 - 8.8e-09 35.2 10.8 1.8e-08 34.2 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME78596.1 - 1.6e-07 31.0 10.9 3.5e-07 29.9 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME78596.1 - 2e-07 30.5 7.9 3.9e-07 29.6 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EME78596.1 - 4.2e-06 26.4 2.4 7.3e-06 25.6 1.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EME78596.1 - 5e-06 26.1 5.3 7e-06 25.6 2.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME78596.1 - 9.1e-06 25.4 10.0 2.1e-05 24.3 7.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EME78596.1 - 0.0005 19.9 0.4 0.0018 18.1 0.0 2.1 3 0 0 3 3 3 1 U-box domain SAP PF02037.22 EME78596.1 - 0.00063 19.1 0.1 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-rbx1 PF12678.2 EME78596.1 - 0.00086 19.3 4.2 0.0021 18.1 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Mob_synth_C PF06463.8 EME78596.1 - 0.001 18.7 4.1 0.0021 17.7 2.3 1.8 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-Apc11 PF12861.2 EME78596.1 - 0.019 14.7 2.1 0.044 13.6 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 EME78596.1 - 0.027 13.9 5.5 0.065 12.7 3.9 1.6 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 EME78596.1 - 0.066 12.7 7.4 0.6 9.7 5.4 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EME78596.1 - 0.55 10.1 7.0 1.4 8.8 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Glyco_hydro_72 PF03198.9 EME78597.1 - 5.3e-116 387.0 0.1 6.6e-116 386.6 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EME78597.1 - 0.00014 21.1 0.0 0.0012 18.0 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HALZ PF02183.13 EME78597.1 - 0.041 13.5 0.2 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pou PF00157.12 EME78597.1 - 0.13 11.9 0.2 11 5.7 0.0 3.0 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain Senescence_reg PF04520.8 EME78599.1 - 0.42 11.0 3.1 0.55 10.7 2.2 1.2 1 0 0 1 1 1 0 Senescence regulator DUF1237 PF06824.6 EME78601.1 - 1.7e-180 600.1 0.0 2e-180 599.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) SdrG_C_C PF10425.4 EME78601.1 - 0.0031 17.4 0.8 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 C-terminus of bacterial fibrinogen-binding adhesin PilM_2 PF11104.3 EME78602.1 - 0.056 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; HSP70 PF00012.15 EME78602.1 - 0.19 9.5 3.3 0.25 9.2 0.2 2.2 2 1 0 2 2 2 0 Hsp70 protein NinF PF05810.7 EME78603.1 - 0.047 13.4 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 NinF protein Metallophos PF00149.23 EME78607.1 - 1.1e-42 145.6 0.4 1.5e-42 145.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nuf2 PF03800.9 EME78609.1 - 3.8e-44 150.2 0.1 3.8e-44 150.2 0.1 2.6 4 0 0 4 4 4 1 Nuf2 family Tropomyosin_1 PF12718.2 EME78609.1 - 0.00064 19.5 21.5 0.00064 19.5 14.9 3.3 1 1 2 3 3 3 1 Tropomyosin like Reo_sigmaC PF04582.7 EME78609.1 - 0.019 14.1 16.1 0.098 11.8 2.4 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein GAS PF13851.1 EME78609.1 - 0.77 8.9 60.0 0.84 8.7 19.3 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EME78609.1 - 4.7 6.7 65.2 26 4.3 19.8 3.6 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 EME78609.1 - 5.1 5.4 44.3 0.62 8.4 11.0 2.6 1 1 1 2 2 2 0 AAA domain Pyrophosphatase PF00719.14 EME78609.1 - 6.9 6.1 8.0 3.4 7.1 0.9 3.0 3 0 0 3 3 3 0 Inorganic pyrophosphatase DUF3584 PF12128.3 EME78609.1 - 9.1 3.4 57.1 23 2.1 39.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Fungal_trans PF04082.13 EME78610.1 - 3.2e-43 147.4 0.1 5.2e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78610.1 - 2.3e-08 33.7 8.4 5.2e-08 32.6 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 EME78611.1 - 5.5 7.0 13.0 0.57 10.1 5.8 1.8 2 0 0 2 2 2 0 bZIP transcription factor Adaptin_N PF01602.15 EME78613.1 - 3e-98 329.4 0.1 4.5e-98 328.8 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EME78613.1 - 3.3e-09 36.8 9.5 0.0046 17.1 0.1 4.9 3 2 1 4 4 4 4 HEAT repeats HEAT PF02985.17 EME78613.1 - 8.8e-09 34.7 1.1 0.024 14.6 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat RasGEF_N_2 PF14663.1 EME78613.1 - 0.0027 17.6 0.1 5.2 7.0 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.2 EME78613.1 - 0.006 16.5 1.3 5.2 7.1 0.2 3.2 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EME78613.1 - 0.011 15.6 0.7 0.055 13.3 0.0 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EME78613.1 - 0.081 12.2 1.2 2.2 7.5 0.0 3.0 2 1 1 3 3 3 0 CLASP N terminal DUF2454 PF10521.4 EME78614.1 - 1.6e-58 197.9 2.1 2.5e-58 197.3 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EME78614.1 - 9.7e-23 80.7 0.3 2.9e-22 79.2 0.2 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EME78614.1 - 1.8e-09 37.0 0.1 4.8e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EME78614.1 - 0.00014 21.6 0.0 0.0004 20.2 0.0 1.8 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 EME78615.1 - 6.1e-109 364.4 0.0 9.6e-109 363.7 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Myb_Cef PF11831.3 EME78618.1 - 5.7e-51 172.9 2.5 5.7e-51 172.9 1.7 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EME78618.1 - 8.6e-21 73.7 4.3 3.7e-10 39.6 0.2 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME78618.1 - 1.2e-19 70.1 6.5 2.3e-13 50.0 1.5 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Amidohydro_4 PF13147.1 EME78620.1 - 3.8e-25 89.4 0.0 5.1e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EME78620.1 - 8.3e-19 68.4 0.0 5.2e-09 36.1 0.2 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EME78620.1 - 1.5e-14 53.5 0.9 3.1e-14 52.5 0.7 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME78620.1 - 3.2e-09 36.5 0.0 7.9e-05 22.0 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.15 EME78620.1 - 0.011 15.8 0.2 0.023 14.8 0.2 1.5 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Nipped-B_C PF12830.2 EME78622.1 - 1.8e-28 99.4 3.2 1.2e-26 93.5 0.1 4.2 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EME78622.1 - 1.5e-07 31.2 2.4 1.5e-07 31.2 1.6 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EME78622.1 - 3.5e-05 23.5 3.2 0.29 11.3 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EME78622.1 - 0.00033 20.5 5.5 0.0024 17.7 0.1 3.1 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EME78622.1 - 0.0087 15.9 1.0 0.11 12.3 0.1 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2435) Spt5_N PF11942.3 EME78622.1 - 0.14 12.7 9.0 0.31 11.6 1.8 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TFIIS_C PF01096.13 EME78623.1 - 1.1e-17 63.3 3.2 1.1e-17 63.3 2.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EME78623.1 - 0.00028 20.5 0.4 0.00028 20.5 0.3 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 EME78623.1 - 0.00044 19.6 7.6 0.7 9.4 0.7 4.1 3 1 1 4 4 4 1 zinc-ribbon domain DZR PF12773.2 EME78623.1 - 0.00056 19.6 8.0 0.018 14.8 0.2 2.6 2 1 0 2 2 2 2 Double zinc ribbon Lar_restr_allev PF14354.1 EME78623.1 - 0.00058 20.1 7.7 0.028 14.7 0.6 3.2 2 1 1 3 3 3 1 Restriction alleviation protein Lar RRN7 PF11781.3 EME78623.1 - 0.0021 17.5 5.7 4.7 6.8 0.1 4.1 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EME78623.1 - 0.0095 15.2 10.2 1.2 8.5 0.2 4.0 3 1 1 4 4 4 1 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 EME78623.1 - 0.016 14.8 6.7 0.41 10.3 0.3 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Mu-like_Com PF10122.4 EME78623.1 - 0.02 13.9 0.2 0.02 13.9 0.1 2.5 3 0 0 3 3 2 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.1 EME78623.1 - 0.021 14.3 6.4 0.36 10.4 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 EME78623.1 - 0.031 13.6 0.0 0.031 13.6 0.0 2.9 3 1 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.5 EME78623.1 - 0.093 12.6 12.0 0.88 9.5 0.4 3.4 2 1 1 3 3 3 0 Zinc ribbon domain Ribosomal_S27e PF01667.12 EME78623.1 - 0.13 11.8 7.5 0.56 9.7 0.3 3.4 3 1 0 3 3 3 0 Ribosomal protein S27 Terminase_GpA PF05876.7 EME78623.1 - 0.17 10.2 4.2 0.039 12.3 1.0 1.5 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) IBR PF01485.16 EME78623.1 - 0.19 11.6 8.8 0.34 10.8 0.1 2.8 2 1 0 2 2 2 0 IBR domain UPF0547 PF10571.4 EME78623.1 - 0.19 11.4 6.9 1 9.1 0.1 3.7 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-CHY PF05495.7 EME78623.1 - 0.2 11.8 6.1 4.3 7.5 0.1 2.4 2 1 0 2 2 2 0 CHY zinc finger zf-3CxxC PF13695.1 EME78623.1 - 0.25 11.6 10.6 1.8 8.8 0.2 3.0 1 1 2 3 3 3 0 Zinc-binding domain zf-ribbon_3 PF13248.1 EME78623.1 - 0.27 10.4 13.5 4.7 6.5 1.6 3.9 3 1 1 4 4 4 0 zinc-ribbon domain HypA PF01155.14 EME78623.1 - 0.33 10.6 7.9 1.9 8.1 0.2 2.7 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Rpr2 PF04032.11 EME78623.1 - 0.39 10.6 7.1 2.5 8.0 0.4 2.4 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DNA_RNApol_7kD PF03604.8 EME78623.1 - 0.47 9.9 9.7 1.2 8.6 1.2 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit OrfB_Zn_ribbon PF07282.6 EME78623.1 - 0.77 9.4 10.8 13 5.4 1.9 3.1 2 2 0 3 3 3 0 Putative transposase DNA-binding domain zf-FPG_IleRS PF06827.9 EME78623.1 - 1.2 8.8 11.8 7.3 6.3 0.3 3.8 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Jiv90 PF14901.1 EME78623.1 - 1.5 8.8 5.2 2.2 8.2 0.3 2.7 2 2 1 3 3 3 0 Cleavage inducing molecular chaperone Zn_ribbon_recom PF13408.1 EME78623.1 - 1.7 8.9 8.4 6 7.2 0.6 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain GFA PF04828.9 EME78623.1 - 1.7 8.6 8.4 4.5 7.2 0.6 3.0 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Transpos_assoc PF13963.1 EME78623.1 - 2.2 8.3 7.3 1.8 8.6 0.1 2.6 2 1 1 3 3 2 0 Transposase-associated domain Zn_Tnp_IS1595 PF12760.2 EME78623.1 - 2.3 8.0 11.4 0.67 9.8 2.5 3.1 2 2 1 3 3 3 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 EME78623.1 - 2.8 8.0 9.7 49 4.0 0.3 4.0 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC4_3 PF13920.1 EME78623.1 - 2.9 7.6 7.2 6 6.6 0.2 2.9 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.11 EME78623.1 - 3.3 7.9 9.5 7.1 6.8 0.1 3.4 3 0 0 3 3 3 0 C1 domain CpXC PF14353.1 EME78623.1 - 5.8 6.8 6.5 35 4.3 1.9 3.0 1 1 2 3 3 3 0 CpXC protein Elf1 PF05129.8 EME78623.1 - 6 6.6 11.7 6.5 6.5 0.2 3.2 2 2 1 3 3 3 0 Transcription elongation factor Elf1 like Nudix_N_2 PF14803.1 EME78623.1 - 7.5 6.3 11.9 4.4 7.0 1.7 3.6 3 1 0 3 3 3 0 Nudix N-terminal Prim_Zn_Ribbon PF08273.7 EME78623.1 - 7.7 6.6 11.7 5.5 7.1 0.0 3.5 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-C2H2_4 PF13894.1 EME78623.1 - 8 7.0 7.8 26 5.4 0.3 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C4_Topoisom PF01396.14 EME78623.1 - 8.4 5.9 8.4 18 4.9 0.1 3.5 3 1 1 4 4 4 0 Topoisomerase DNA binding C4 zinc finger HEAT_2 PF13646.1 EME78624.1 - 2e-35 120.8 0.8 1.3e-14 54.2 0.0 3.2 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EME78624.1 - 1.2e-22 78.0 0.5 0.01 16.2 0.1 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EME78624.1 - 6.8e-09 35.9 3.9 0.0054 17.1 0.2 5.4 4 2 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EME78624.1 - 0.00012 21.8 7.5 0.7 10.1 0.0 5.6 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 EME78624.1 - 0.022 14.5 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EME78624.1 - 0.039 13.9 0.0 0.36 10.8 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TPR_14 PF13428.1 EME78624.1 - 0.097 13.3 0.7 6.8 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-ZPR1 PF03367.8 EME78624.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 ZPR1 zinc-finger domain DUF1681 PF07933.9 EME78625.1 - 1.3e-54 184.1 0.0 1.6e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) She9_MDM33 PF05546.6 EME78626.1 - 1.6e-54 184.6 4.7 2.8e-54 183.8 3.2 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family DUF826 PF05696.6 EME78626.1 - 0.031 14.4 0.1 0.031 14.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF826) FliJ PF02050.11 EME78626.1 - 0.65 10.0 10.2 0.33 11.0 1.3 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein HAD PF12710.2 EME78627.1 - 1.7e-10 41.4 0.0 3.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EME78627.1 - 9.5e-05 21.6 0.0 0.00046 19.4 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 EME78627.1 - 0.0029 16.9 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) SH3_4 PF06347.8 EME78628.1 - 0.09 12.3 0.3 5.6 6.5 0.0 3.0 3 0 0 3 3 3 0 Bacterial SH3 domain Peptidase_C12 PF01088.16 EME78629.1 - 1.7e-66 223.4 0.0 2e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UDPG_MGDP_dh_N PF03721.9 EME78631.1 - 9.6e-56 188.0 0.0 1.9e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EME78631.1 - 5e-32 110.2 0.5 4.6e-26 91.0 0.1 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EME78631.1 - 2.1e-29 101.6 0.0 4.5e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EME78631.1 - 0.00017 21.3 0.3 0.019 14.6 0.0 3.0 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EME78631.1 - 0.00095 19.3 0.2 2.4 8.4 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding DUF2851 PF11013.3 EME78631.1 - 0.019 13.6 0.1 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) 3HCDH_N PF02737.13 EME78631.1 - 0.023 14.3 0.0 0.11 12.1 0.0 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME78631.1 - 0.028 14.2 0.0 0.34 10.7 0.0 2.7 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.18 EME78631.1 - 0.036 13.8 0.3 16 5.2 0.0 3.0 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EME78631.1 - 0.047 12.6 0.0 0.085 11.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_18 PF12847.2 EME78631.1 - 0.068 13.7 0.2 0.74 10.4 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EME78631.1 - 0.095 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain ApbA PF02558.11 EME78631.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPT PF03151.11 EME78632.1 - 3.6e-22 78.6 10.5 3.6e-22 78.6 7.2 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME78632.1 - 7.3e-17 61.2 20.4 1.1e-16 60.5 14.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME78632.1 - 0.0003 20.8 29.1 0.00064 19.7 4.9 3.1 2 2 1 3 3 3 2 EamA-like transporter family Ribosom_S12_S23 PF00164.20 EME78635.1 - 3.7e-41 139.3 1.4 4.7e-41 139.0 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LtrA PF06772.6 EME78636.1 - 1.2e-13 50.7 33.2 6.9e-12 44.9 20.3 2.8 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) TerC PF03741.11 EME78636.1 - 0.0038 16.6 0.0 0.0038 16.6 0.0 2.4 3 0 0 3 3 3 1 Integral membrane protein TerC family SPC12 PF06645.8 EME78636.1 - 0.41 10.4 5.6 0.2 11.4 0.2 3.1 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GILT PF03227.11 EME78638.1 - 1.7e-15 56.7 0.7 3.1e-15 55.9 0.2 1.7 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) RNase_PH PF01138.16 EME78639.1 - 6.5e-27 94.4 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pmp3 PF01679.12 EME78640.1 - 1.5e-18 66.2 6.6 1.9e-18 65.8 4.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FAD_binding_4 PF01565.18 EME78641.1 - 7.6e-19 67.5 0.0 1.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EME78642.1 - 1e-72 245.1 0.0 1.3e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EME78642.1 - 4.4e-41 140.2 0.1 7.3e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EME78642.1 - 0.0034 17.7 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME78642.1 - 0.0068 15.3 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME78642.1 - 0.01 15.7 0.1 0.072 12.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME78642.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME78642.1 - 0.026 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EME78642.1 - 0.036 12.9 0.0 0.21 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.1 EME78642.1 - 0.08 13.2 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain ThiF PF00899.16 EME78642.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EME78642.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EME78643.1 - 3.6e-13 49.7 0.6 4.2e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME78643.1 - 2.7e-07 30.4 0.0 5.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME78643.1 - 0.00023 20.6 0.1 0.00056 19.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME78643.1 - 0.085 12.8 0.2 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Beta-Casp PF10996.3 EME78643.1 - 0.15 12.0 0.4 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 Beta-Casp domain Lsr2 PF11774.3 EME78643.1 - 0.68 9.8 5.9 1.4 8.8 4.1 1.5 1 0 0 1 1 1 0 Lsr2 Lipase_2 PF01674.13 EME78646.1 - 6.6e-09 35.4 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.2 EME78646.1 - 1.4e-05 25.1 0.1 2e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78646.1 - 0.00023 20.7 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78646.1 - 0.0038 17.0 0.2 0.0067 16.1 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family CAF1A PF12253.3 EME78647.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DUF1534 PF07551.6 EME78648.1 - 0.38 10.3 3.6 0.38 10.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) Actin PF00022.14 EME78649.1 - 5.6e-90 301.5 0.0 1.3e-89 300.4 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME78649.1 - 0.0081 14.7 0.0 0.32 9.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 EME78650.1 - 8.5e-36 123.2 3.6 2.1e-22 79.2 0.0 2.2 1 1 0 2 2 2 2 Asparaginase BTB PF00651.26 EME78651.1 - 6.7e-15 55.0 0.2 1.9e-13 50.3 0.0 2.5 1 1 1 2 2 2 1 BTB/POZ domain PHP_C PF13263.1 EME78651.1 - 0.067 12.7 0.2 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 PHP-associated GDPD PF03009.12 EME78654.1 - 1.7e-10 40.8 0.0 3.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PNTB PF02233.11 EME78657.1 - 1.6e-166 554.6 24.0 1.6e-166 554.6 16.6 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EME78657.1 - 2.5e-55 186.5 1.2 4.8e-55 185.6 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EME78657.1 - 1.2e-37 128.9 0.4 4.3e-37 127.1 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EME78657.1 - 6.2e-32 109.6 4.1 6.2e-32 109.6 2.8 5.6 6 1 0 6 6 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EME78657.1 - 3.9e-06 26.1 0.8 0.89 8.6 0.1 3.5 2 1 1 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EME78657.1 - 0.0058 16.1 3.0 0.011 15.3 0.2 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EME78657.1 - 0.028 14.3 0.9 0.073 12.9 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 EME78657.1 - 0.041 13.6 0.2 0.2 11.4 0.1 2.2 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain CP_ATPgrasp_1 PF04174.8 EME78657.1 - 0.046 12.3 0.0 0.081 11.5 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Methyltransf_31 PF13847.1 EME78657.1 - 0.061 12.9 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME78657.1 - 0.15 12.6 0.0 0.47 11.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_8 PF13450.1 EME78657.1 - 1.2 9.1 5.2 0.36 10.8 0.6 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EME78658.1 - 6.3e-09 35.7 0.0 2.1e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 ThiF family Abhydrolase_6 PF12697.2 EME78659.1 - 2.4e-33 115.9 0.1 2.9e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME78659.1 - 2e-14 53.5 0.0 2.7e-14 53.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78659.1 - 3.1e-13 49.8 0.7 1.2e-12 47.9 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME78659.1 - 1.2e-08 34.7 0.4 3.3e-08 33.2 0.2 1.9 2 0 0 2 2 2 1 Putative lysophospholipase LCAT PF02450.10 EME78659.1 - 0.00077 18.5 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EME78659.1 - 0.019 14.3 0.3 0.072 12.3 0.2 1.8 1 1 0 1 1 1 0 Lipase (class 2) DUF900 PF05990.7 EME78659.1 - 0.037 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) adh_short_C2 PF13561.1 EME78660.1 - 4.2e-30 105.2 0.0 5e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME78660.1 - 1.8e-15 57.2 0.2 3.1e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 EME78661.1 - 4.5e-10 38.8 1.0 9.3e-10 37.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rib_5-P_isom_A PF06026.9 EME78662.1 - 3.7e-36 124.0 0.0 3.2e-34 117.7 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF4185 PF13810.1 EME78663.1 - 0.005 15.7 0.2 0.008 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) DUF1680 PF07944.7 EME78665.1 - 6.6e-97 324.9 0.0 8.2e-97 324.6 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) OPT PF03169.10 EME78666.1 - 6.8e-149 497.1 48.8 7.7e-149 496.9 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribosomal_S5_C PF03719.10 EME78667.1 - 1.1e-17 62.9 0.1 8.6e-17 60.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EME78667.1 - 6.4e-09 35.4 0.4 1.6e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain CENP-H PF05837.7 EME78667.1 - 0.045 13.9 1.6 4.3 7.5 0.1 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Oligomerisation PF02410.10 EME78668.1 - 6.2e-08 32.5 0.1 0.0033 17.4 0.0 3.0 3 1 0 3 3 3 2 Oligomerisation domain Peptidase_M15_2 PF05951.8 EME78669.1 - 0.12 11.8 0.2 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) Methyltransf_33 PF10017.4 EME78671.1 - 6.1e-33 113.4 0.3 1.2e-32 112.5 0.2 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EME78671.1 - 4.1e-16 59.1 0.0 1.6e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EME78671.1 - 1.2e-06 28.9 0.2 2.6e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 DinB superfamily BNR_2 PF13088.1 EME78673.1 - 0.021 14.1 0.4 0.24 10.6 0.0 2.3 2 1 1 3 3 3 0 BNR repeat-like domain BatD PF13584.1 EME78673.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance BNR PF02012.15 EME78673.1 - 2.8 8.1 5.7 1.9 8.6 0.2 3.1 2 1 0 2 2 2 0 BNR/Asp-box repeat TPP_enzyme_N PF02776.13 EME78674.1 - 7e-32 110.2 0.2 1.1e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME78674.1 - 1.8e-18 66.6 0.0 9.7e-18 64.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME78674.1 - 1.4e-17 63.7 0.0 3.2e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pex2_Pex12 PF04757.9 EME78675.1 - 6.4e-55 186.0 0.6 8e-55 185.7 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EME78675.1 - 0.0011 18.7 0.3 0.0018 18.0 0.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EME78675.1 - 0.0021 18.0 0.3 0.0035 17.3 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME78675.1 - 0.0059 16.3 0.3 0.0099 15.6 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME78675.1 - 0.05 13.2 0.2 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lar_restr_allev PF14354.1 EME78675.1 - 0.083 13.1 0.6 0.16 12.2 0.4 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar DASH_Dad1 PF08649.5 EME78676.1 - 1.6e-25 88.5 1.2 1.9e-25 88.2 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 PilJ PF13675.1 EME78676.1 - 0.0086 16.3 0.1 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term WVELL PF14043.1 EME78676.1 - 0.053 13.1 0.1 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 WVELL protein Occludin_ELL PF07303.8 EME78676.1 - 0.1 13.3 0.1 0.12 13.0 0.1 1.1 1 0 0 1 1 1 0 Occludin homology domain Ras PF00071.17 EME78677.1 - 6.2e-49 165.4 0.0 7.9e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME78677.1 - 1.3e-11 44.9 0.0 2.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME78677.1 - 3.2e-05 23.2 0.0 5.3e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME78677.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.16 EME78678.1 - 6.9e-17 61.3 5.4 6.9e-17 61.3 3.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily Ank PF00023.25 EME78680.1 - 1.4e-27 94.0 8.8 9.8e-08 31.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EME78680.1 - 5.7e-26 90.6 2.3 1.4e-20 73.4 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME78680.1 - 1.9e-23 82.3 4.0 2.7e-09 37.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME78680.1 - 2.6e-23 79.7 2.6 1.9e-06 27.5 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EME78680.1 - 4e-18 65.0 3.4 8.2e-08 32.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Epimerase PF01370.16 EME78682.1 - 6.9e-31 107.4 0.0 9.6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME78682.1 - 2.1e-06 26.8 0.0 3.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EME78682.1 - 7.1e-06 24.9 0.0 1.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME78682.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding RNase_P_Rpp14 PF01900.14 EME78683.1 - 2e-34 117.6 0.0 2.3e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family NUC153 PF08159.7 EME78684.1 - 2.3e-17 62.2 8.6 3.1e-14 52.2 0.2 3.7 3 0 0 3 3 3 2 NUC153 domain Herpes_LMP1 PF05297.6 EME78684.1 - 0.2 10.5 0.2 0.42 9.4 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Voltage_CLC PF00654.15 EME78685.1 - 6.9e-90 301.6 27.9 6.9e-90 301.6 19.3 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EME78685.1 - 2.5e-12 46.3 0.0 6.9e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 EME78686.1 - 4.4e-12 45.8 0.0 7.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME78686.1 - 0.0012 18.9 0.1 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 EME78686.1 - 0.053 13.3 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region MoCF_biosynth PF00994.19 EME78687.1 - 1.2e-52 177.1 0.5 3.7e-30 104.2 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EME78687.1 - 5.7e-36 123.3 2.6 9.5e-36 122.5 1.8 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EME78687.1 - 7.6e-16 57.8 0.0 1.6e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 EME78687.1 - 1.2 8.4 10.7 1.8 7.8 7.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_tranf_2_3 PF13641.1 EME78688.1 - 9.2e-22 77.9 0.0 1.3e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME78688.1 - 6.5e-19 68.3 3.8 6.5e-19 68.3 2.6 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EME78688.1 - 3.3e-09 36.2 0.0 5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME78688.1 - 0.0002 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.16 EME78690.1 - 5.6e-07 29.0 0.0 2e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acyl_transf_3 PF01757.17 EME78690.1 - 4.5e-06 25.7 45.8 9.5e-06 24.6 31.7 1.5 1 0 0 1 1 1 1 Acyltransferase family EHN PF06441.7 EME78691.1 - 8.7e-37 125.4 2.0 6.9e-36 122.5 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EME78691.1 - 3.2e-11 43.5 0.3 1e-10 41.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78691.1 - 7.4e-08 32.2 0.0 1.6e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Metallophos PF00149.23 EME78693.1 - 8.6e-30 103.6 0.3 4.2e-22 78.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase FAD_binding_2 PF00890.19 EME78694.1 - 2.4e-31 108.9 0.0 1.7e-15 56.7 0.0 2.0 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EME78694.1 - 0.016 15.0 0.0 0.23 11.3 0.0 2.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ETC_C1_NDUFA4 PF04800.7 EME78699.1 - 1.3e-36 124.4 0.8 2e-36 123.8 0.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EME78700.1 - 2.3e-36 123.9 0.4 2.5e-36 123.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EME78700.1 - 0.0041 17.1 0.4 0.0053 16.7 0.3 1.2 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Init_tRNA_PT PF04179.7 EME78703.1 - 0.15 10.8 0.1 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Arrestin_C PF02752.17 EME78704.1 - 3e-15 56.5 0.0 1.1e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EME78705.1 - 4.7e-47 160.0 0.0 5.4e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1446 PF07287.6 EME78708.1 - 6.4e-128 426.2 0.1 7.8e-128 425.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Pyridox_oxidase PF01243.15 EME78708.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BPL_N PF09825.4 EME78709.1 - 1.4e-13 50.3 0.2 6.7e-09 35.0 0.2 2.1 1 1 0 2 2 2 2 Biotin-protein ligase, N terminal GATase_3 PF07685.9 EME78709.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Glyco_hydro_42M PF08532.5 EME78709.1 - 0.044 12.9 0.1 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain MFS_1 PF07690.11 EME78710.1 - 1.8e-40 138.7 43.0 1.2e-37 129.4 30.6 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME78710.1 - 2.1e-14 52.9 13.4 2.1e-14 52.9 9.3 3.5 3 1 1 4 4 4 1 Sugar (and other) transporter DUF1115 PF06544.7 EME78711.1 - 5.7e-18 64.8 0.0 1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb4 PF03874.11 EME78711.1 - 0.022 14.7 0.9 4.2 7.4 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 DUF2570 PF10828.3 EME78711.1 - 0.1 12.1 0.6 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) HTH_43 PF09904.4 EME78711.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix PALP PF00291.20 EME78712.1 - 7.2e-29 100.9 0.0 1.2e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EME78712.1 - 1.8e-06 28.2 0.0 8e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain NAF PF03822.9 EME78712.1 - 0.087 12.5 0.1 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 NAF domain DUF1772 PF08592.6 EME78715.1 - 8.5e-13 48.2 0.1 1.5e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Yip1 PF04893.12 EME78715.1 - 0.0096 15.4 1.4 0.016 14.7 1.0 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EME78715.1 - 0.011 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) MFS_1 PF07690.11 EME78717.1 - 3e-22 78.8 48.2 4.6e-15 55.1 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tfb4 PF03850.9 EME78718.1 - 2.5e-99 331.9 0.0 2.9e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EME78718.1 - 0.065 13.3 1.6 0.12 12.4 1.1 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Sigma70_ner PF04546.8 EME78722.1 - 5.5 6.5 7.2 9.3 5.7 5.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CPSase_L_D2 PF02786.12 EME78724.1 - 3.1e-114 379.5 0.1 1.3e-82 276.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EME78724.1 - 5.3e-47 159.7 0.0 1.3e-46 158.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EME78724.1 - 5.1e-44 148.9 0.0 1.7e-42 144.0 0.0 2.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EME78724.1 - 1.9e-42 144.2 0.0 3.9e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EME78724.1 - 2.8e-41 140.1 0.0 5.8e-41 139.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EME78724.1 - 5.8e-41 139.0 0.2 1.7e-19 69.9 0.0 3.7 4 0 0 4 4 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EME78724.1 - 4.4e-37 127.5 0.2 4.6e-21 75.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EME78724.1 - 2.7e-34 118.3 0.0 8.5e-34 116.7 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EME78724.1 - 4.3e-23 81.5 0.1 2.7e-11 42.7 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EME78724.1 - 1.5e-18 66.4 0.0 8e-18 64.1 0.0 2.4 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 EME78724.1 - 9.5e-18 64.1 0.1 1.3e-08 34.3 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME78724.1 - 6.1e-17 61.6 0.2 1.6e-08 34.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EME78724.1 - 6.4e-07 29.3 0.4 0.023 14.5 0.1 2.8 3 0 0 3 3 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EME78724.1 - 2.6e-06 27.0 0.1 0.00011 21.7 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 EME78724.1 - 3.2e-06 26.7 0.0 0.00011 21.7 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EME78724.1 - 2.1e-05 24.1 0.3 0.13 11.8 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EME78724.1 - 0.0012 18.2 0.0 0.0039 16.6 0.0 1.8 1 0 0 1 1 1 1 DJ-1/PfpI family TrkA_N PF02254.13 EME78724.1 - 0.062 13.3 0.1 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain RAP PF08373.5 EME78724.1 - 0.14 11.9 0.0 4.1 7.2 0.0 2.8 2 0 0 2 2 2 0 RAP domain Svf1 PF08622.5 EME78725.1 - 1.7e-123 411.7 0.3 2e-123 411.5 0.2 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EME78725.1 - 0.015 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Histone PF00125.19 EME78726.1 - 0.0032 17.5 0.6 0.071 13.2 0.4 2.1 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4095 PF13338.1 EME78726.1 - 0.029 14.5 0.1 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) Reo_sigmaC PF04582.7 EME78727.1 - 0.00027 20.2 17.5 0.14 11.2 2.4 4.3 1 1 2 4 4 4 3 Reovirus sigma C capsid protein Filament PF00038.16 EME78727.1 - 0.00083 18.9 33.1 0.00083 18.9 22.9 4.7 1 1 2 4 4 4 3 Intermediate filament protein ATG16 PF08614.6 EME78727.1 - 0.013 15.3 78.6 0.018 14.8 5.6 6.5 1 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EME78727.1 - 0.026 12.2 87.0 0.22 9.1 31.1 3.0 1 1 2 3 3 3 0 Myosin tail TMF_DNA_bd PF12329.3 EME78727.1 - 0.037 13.8 0.6 0.037 13.8 0.4 8.5 4 2 6 10 10 10 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EME78727.1 - 0.04 13.5 85.0 0.036 13.6 9.7 4.6 1 1 4 5 5 5 0 IncA protein CENP-F_leu_zip PF10473.4 EME78727.1 - 0.18 11.6 82.5 0.23 11.2 12.6 5.7 1 1 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EME78727.1 - 0.26 9.7 64.1 0.23 9.8 5.0 3.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF972 PF06156.8 EME78727.1 - 0.31 11.4 57.5 1.7 8.9 0.7 7.3 1 1 6 8 8 8 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 EME78727.1 - 0.38 10.5 67.3 0.026 14.2 4.9 6.3 1 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 EME78727.1 - 0.61 9.9 16.2 4.3 7.2 0.4 5.9 2 2 5 8 8 8 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.6 EME78727.1 - 0.93 8.8 23.1 0.25 10.7 0.5 5.3 4 1 1 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) ERM PF00769.14 EME78727.1 - 1 8.8 72.8 0.052 13.0 9.4 4.5 1 1 3 4 4 4 0 Ezrin/radixin/moesin family DUF3450 PF11932.3 EME78727.1 - 1.6 7.9 39.9 1.1 8.4 0.9 5.6 1 1 3 5 5 5 0 Protein of unknown function (DUF3450) AHS1 PF02682.11 EME78727.1 - 2.8 7.3 6.3 2.6 7.4 0.5 2.9 1 1 1 3 3 3 0 Allophanate hydrolase subunit 1 DUF3176 PF11374.3 EME78728.1 - 2.8e-34 117.2 2.5 4.1e-34 116.7 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF996 PF06195.8 EME78728.1 - 0.049 13.6 0.1 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF996) FAD_binding_3 PF01494.14 EME78729.1 - 1.2e-15 57.4 0.0 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME78729.1 - 1.3e-08 34.1 0.2 0.00059 18.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME78729.1 - 2.3e-05 24.7 0.0 0.00052 20.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EME78729.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EME78729.1 - 0.041 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME78729.1 - 0.046 12.7 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME78729.1 - 0.12 12.2 0.3 1.2 8.9 0.2 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_6 PF14259.1 EME78730.1 - 7.2e-05 22.6 0.1 0.00045 20.1 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME78730.1 - 0.00017 21.1 0.0 0.0061 16.1 0.0 2.6 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78730.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1643 PF07799.7 EME78732.1 - 0.022 14.4 0.2 0.034 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Pil1 PF13805.1 EME78732.1 - 0.081 12.0 0.3 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Eisosome component PIL1 SNF2_N PF00176.18 EME78733.1 - 4.1e-51 173.5 0.0 6.1e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME78733.1 - 6.8e-10 38.6 0.0 1.7e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EME78733.1 - 0.0058 16.3 15.4 0.014 15.1 10.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME78733.1 - 0.087 12.5 12.6 0.17 11.5 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME78733.1 - 0.2 11.5 16.5 0.76 9.6 11.4 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EME78733.1 - 0.44 10.6 15.1 1.2 9.2 10.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME78733.1 - 3.7 7.5 13.9 8.3 6.3 9.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Na_Ca_ex PF01699.19 EME78734.1 - 6.5e-45 152.1 33.2 6.6e-23 80.8 8.4 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein zf-CCCH PF00642.19 EME78735.1 - 1.6e-06 27.5 1.8 1.6e-06 27.5 1.2 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 6PGD PF00393.14 EME78741.1 - 0.34 10.0 0.0 0.56 9.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Cmc1 PF08583.5 EME78742.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4185 PF13810.1 EME78743.1 - 4.6e-07 29.0 0.1 7e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Peroxidase_2 PF01328.12 EME78744.1 - 3.1e-31 108.2 0.0 3.3e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Orthopox_A47 PF06334.6 EME78744.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A47 protein AMP-binding PF00501.23 EME78745.1 - 6.1e-66 222.5 0.0 8.9e-65 218.7 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME78745.1 - 2.5e-14 53.9 0.2 5.4e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CoA_transf_3 PF02515.12 EME78746.1 - 4e-61 205.5 0.1 5.1e-61 205.2 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III HMGL-like PF00682.14 EME78747.1 - 7e-49 166.6 0.0 1e-48 166.0 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 EME78747.1 - 2.8e-34 118.3 0.0 4.8e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Aldedh PF00171.17 EME78748.1 - 1.3e-106 356.7 5.6 2e-66 224.2 1.8 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME78748.1 - 0.00014 21.1 0.1 0.47 9.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Acyl-CoA_dh_1 PF00441.19 EME78749.1 - 1.7e-38 132.0 3.1 3.2e-38 131.1 2.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME78749.1 - 2.8e-21 76.1 0.0 6.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME78749.1 - 1e-15 58.1 0.7 2.3e-15 57.0 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME78749.1 - 1.3e-10 40.6 0.0 2.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glucosaminidase PF01832.15 EME78749.1 - 0.046 13.8 1.7 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Mito_carr PF00153.22 EME78750.1 - 9.6e-55 182.2 6.0 3.1e-20 71.6 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ECH PF00378.15 EME78751.1 - 7e-42 143.2 0.0 4.2e-41 140.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family adh_short PF00106.20 EME78752.1 - 4.8e-08 33.1 0.1 7.2e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME78752.1 - 5.4e-06 26.1 0.2 1.1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EME78752.1 - 0.036 12.9 0.1 0.6 8.9 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Inositol_P PF00459.20 EME78753.1 - 1e-37 129.9 0.0 2.5e-37 128.6 0.0 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DUF1349 PF07081.6 EME78755.1 - 3.6e-27 94.8 0.5 3.9e-27 94.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) BChl_A PF02327.12 EME78756.1 - 0.1 11.2 0.2 0.12 10.9 0.1 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein GMC_oxred_N PF00732.14 EME78760.1 - 9.2e-67 225.2 0.0 1.3e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME78760.1 - 3.1e-36 124.8 0.0 1.3e-35 122.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EME78760.1 - 1e-06 27.9 0.2 1.2e-05 24.4 0.1 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME78760.1 - 0.0001 22.2 0.0 0.00034 20.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME78760.1 - 0.00074 19.6 0.3 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME78760.1 - 0.00079 18.4 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME78760.1 - 0.0022 16.9 0.1 0.055 12.3 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EME78760.1 - 0.061 11.7 0.1 0.33 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EME78760.1 - 0.13 12.1 0.2 0.58 10.0 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3337 PF11816.3 EME78763.1 - 2.5e-80 270.3 0.0 1e-75 255.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EME78763.1 - 2.2e-29 100.2 11.3 2.2e-08 33.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat GWT1 PF06423.7 EME78765.1 - 0.076 13.1 0.3 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 GWT1 Zw10 PF06248.8 EME78765.1 - 0.097 10.8 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Fig1 PF12351.3 EME78765.1 - 0.2 11.4 10.6 0.13 12.1 4.8 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Cpn60_TCP1 PF00118.19 EME78766.1 - 1.5e-139 465.7 12.2 1.7e-139 465.5 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.11 EME78769.1 - 1e-13 50.7 22.6 1e-13 50.7 15.7 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily RecX PF02631.11 EME78769.1 - 0.096 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 RecX family adh_short_C2 PF13561.1 EME78770.1 - 1.1e-26 94.0 0.1 1.3e-26 93.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME78770.1 - 1e-25 90.5 0.2 1.5e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME78770.1 - 1.1e-08 34.9 1.8 6.8e-08 32.3 1.2 2.0 1 1 0 1 1 1 1 KR domain F-box-like_2 PF13013.1 EME78771.1 - 0.049 13.3 1.3 0.24 11.1 0.8 2.4 2 1 0 2 2 2 0 F-box-like domain Nif11 PF07862.6 EME78771.1 - 0.21 11.5 0.7 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function SGL PF08450.7 EME78772.1 - 8.7e-08 31.8 0.1 0.00035 20.0 0.1 2.1 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EME78772.1 - 0.17 11.9 0.9 14 5.8 0.0 3.6 3 0 0 3 3 3 0 NHL repeat Flagellin_D3 PF08884.6 EME78772.1 - 0.7 10.1 5.9 1.2 9.3 0.2 2.7 2 2 2 4 4 4 0 Flagellin D3 domain FAD_binding_3 PF01494.14 EME78774.1 - 2.6e-13 49.7 0.1 5.7e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME78774.1 - 2e-06 27.7 1.4 2.9e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME78774.1 - 7.9e-05 21.7 0.6 0.00018 20.5 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME78774.1 - 9.3e-05 22.2 2.7 0.00038 20.2 0.9 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME78774.1 - 0.00049 19.1 0.8 0.16 10.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 EME78774.1 - 0.0037 17.6 0.2 0.011 16.1 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME78774.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME78774.1 - 0.014 14.2 1.9 0.021 13.6 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 EME78774.1 - 0.033 13.6 0.2 0.07 12.5 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EME78774.1 - 0.036 14.1 0.3 0.094 12.7 0.2 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME78774.1 - 0.052 12.0 0.0 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.19 EME78774.1 - 0.073 12.1 1.1 4.3 6.2 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Cyclin_N PF00134.18 EME78775.1 - 4.7e-12 45.5 1.1 1.4e-11 44.0 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EME78775.1 - 0.044 13.5 0.5 0.13 12.1 0.3 1.8 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Vinculin PF01044.14 EME78775.1 - 0.18 9.7 0.1 0.27 9.1 0.1 1.2 1 0 0 1 1 1 0 Vinculin family Sugar_tr PF00083.19 EME78776.1 - 1.5e-69 234.7 19.9 2.4e-51 174.7 2.1 4.0 2 1 2 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.11 EME78776.1 - 3.2e-06 26.1 29.4 5.2e-06 25.4 12.6 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Oxidored_q4 PF00507.14 EME78776.1 - 4.7 7.0 12.2 0.079 12.7 3.2 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MFS_1 PF07690.11 EME78777.1 - 1.8e-39 135.4 24.8 1.8e-39 135.4 17.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.6 EME78777.1 - 0.028 14.1 0.9 0.028 14.1 0.6 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF485 PF04341.7 EME78777.1 - 0.8 9.4 9.7 18 5.1 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF4188 PF13826.1 EME78778.1 - 1e-36 125.5 0.7 1.5e-36 124.9 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EME78778.1 - 0.00064 18.8 3.3 0.00097 18.2 1.9 1.5 1 1 0 1 1 1 1 Haem-containing dehydratase HAD_2 PF13419.1 EME78779.1 - 2e-13 50.9 0.0 2.6e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME78779.1 - 2e-05 25.0 0.0 2.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME78779.1 - 0.00032 20.3 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 EME78779.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) tRNA_U5-meth_tr PF05958.6 EME78780.1 - 2.3e-12 46.2 0.0 1.7e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EME78780.1 - 4.3e-07 29.6 0.1 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EME78780.1 - 1.1e-05 25.0 0.1 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.15 EME78780.1 - 1.5e-05 24.6 0.0 3.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 EME78780.1 - 3.3e-05 23.8 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME78780.1 - 0.0028 17.9 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME78780.1 - 0.003 18.1 0.0 0.0064 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME78780.1 - 0.0033 16.6 0.1 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EME78780.1 - 0.0084 16.5 0.0 0.032 14.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltrans_SAM PF10672.4 EME78780.1 - 0.019 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Met_10 PF02475.11 EME78780.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Histone PF00125.19 EME78784.1 - 0.0033 17.5 0.1 0.0042 17.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SET PF00856.23 EME78785.1 - 5.1e-14 52.8 0.1 2.5e-12 47.4 0.0 2.9 2 1 0 2 2 2 1 SET domain Sugar_tr PF00083.19 EME78786.1 - 3e-84 283.1 20.3 3.5e-84 282.9 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78786.1 - 7.5e-23 80.8 40.8 6.6e-16 57.9 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EME78786.1 - 3.2 5.6 12.4 0.46 8.4 0.0 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GST_N_2 PF13409.1 EME78787.1 - 1.9e-20 72.6 0.1 6.5e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME78787.1 - 9.1e-16 57.5 0.0 3.8e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME78787.1 - 1.2e-08 34.8 0.0 3.7e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME78787.1 - 6.5e-07 29.4 0.1 3.1e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME78787.1 - 0.0009 19.6 0.0 0.0026 18.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aspzincin_M35 PF14521.1 EME78787.1 - 0.058 13.8 0.2 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase UPF0175 PF03683.8 EME78787.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Pantoate_ligase PF02569.10 EME78788.1 - 3.1e-82 275.5 0.0 4.6e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 EME78789.1 - 3.4e-38 130.7 0.0 5.5e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME78789.1 - 5.7e-20 70.9 0.0 1.3e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EME78789.1 - 1.3e-17 63.0 0.7 2.8e-17 62.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EME78789.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AMP-binding PF00501.23 EME78790.1 - 5.6e-90 301.7 0.0 7.1e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME78790.1 - 2.1e-09 38.1 0.1 6.3e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3608 PF12257.3 EME78791.1 - 3.6e-49 167.1 0.9 3.7e-48 163.8 0.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EME78791.1 - 6e-21 73.9 0.2 1.4e-20 72.8 0.2 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF-hand_6 PF13405.1 EME78792.1 - 2.5e-07 30.0 0.4 0.024 14.5 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EME78792.1 - 2.1e-05 24.5 0.7 2.1e-05 24.5 0.5 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EME78792.1 - 2.1e-05 23.4 0.0 6.6e-05 21.9 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EME78792.1 - 0.00037 19.6 0.0 0.0011 18.2 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EME78792.1 - 0.0031 17.1 0.1 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair Toprim_2 PF13155.1 EME78792.1 - 0.0075 16.5 0.7 0.016 15.5 0.5 1.7 1 1 0 1 1 1 1 Toprim-like Gag_p6 PF08705.6 EME78792.1 - 0.057 13.4 0.2 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Gag protein p6 PAS_3 PF08447.6 EME78792.1 - 0.062 13.4 0.7 9.7 6.3 0.2 2.3 2 0 0 2 2 2 0 PAS fold DUF1057 PF06342.7 EME78792.1 - 1.6 7.5 10.6 0.25 10.1 0.8 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) DNA_pol3_a_NII PF11490.3 EME78792.1 - 2.9 7.5 7.2 4 7.0 2.9 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II p450 PF00067.17 EME78794.1 - 2e-64 217.8 0.0 2.4e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EME78795.1 - 9.3e-33 113.3 32.2 9.3e-33 113.3 22.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME78795.1 - 2.3e-10 39.6 15.0 2.3e-10 39.6 10.4 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.13 EME78796.1 - 2.6e-15 56.0 2.1 4.2e-15 55.3 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADC PF06314.6 EME78798.1 - 2.1e-11 43.6 0.0 3.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.14 EME78798.1 - 2.4e-11 43.3 0.2 2.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Cupin_2 PF07883.6 EME78799.1 - 1.3e-07 31.0 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EME78799.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) zf-MYND PF01753.13 EME78801.1 - 1e-09 38.0 14.5 1.9e-09 37.2 10.1 1.4 1 1 0 1 1 1 1 MYND finger CH PF00307.26 EME78801.1 - 0.082 12.9 0.3 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain zf-Mss51 PF13824.1 EME78801.1 - 1.2 9.0 6.4 1.8 8.4 4.4 1.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1290 PF06947.7 EME78802.1 - 1.6 8.6 6.2 9.3 6.2 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) CTNNBL PF08216.6 EME78803.1 - 3.1e-31 107.1 0.0 1e-30 105.5 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EME78803.1 - 0.01 16.0 3.9 0.13 12.5 0.1 4.1 5 0 0 5 5 5 0 HEAT repeats Ribosomal_S5_C PF03719.10 EME78803.1 - 0.033 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain UPF0184 PF03670.8 EME78803.1 - 0.27 11.4 0.0 0.27 11.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Fungal_trans PF04082.13 EME78804.1 - 9.5e-12 44.3 0.0 1.5e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RecO_C PF02565.10 EME78804.1 - 0.061 13.1 0.1 0.16 11.8 0.1 1.8 1 0 0 1 1 1 0 Recombination protein O C terminal Pkinase PF00069.20 EME78805.1 - 1.5e-24 86.5 0.0 4.2e-20 72.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME78805.1 - 0.0024 17.0 0.0 0.02 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase TFIID_30kDa PF03540.8 EME78807.1 - 5e-25 87.0 0.2 7.5e-25 86.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EME78807.1 - 0.24 11.8 3.2 0.33 11.4 0.8 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 F-box PF00646.28 EME78809.1 - 0.00095 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME78809.1 - 0.0082 15.8 0.1 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like Mre11_DNA_bind PF04152.9 EME78810.1 - 2.8e-49 167.3 0.4 2.8e-49 167.3 0.3 1.7 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EME78810.1 - 1.2e-26 93.3 2.1 1.8e-26 92.7 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME78810.1 - 3e-07 30.4 0.1 8.4e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EME78810.1 - 0.06 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Ribosomal_S19 PF00203.16 EME78811.1 - 3.8e-24 84.1 0.1 4.6e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Rod_cone_degen PF15201.1 EME78813.1 - 0.019 14.8 0.2 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Progressive rod-cone degeneration DUF3504 PF12012.3 EME78814.1 - 1.6 8.4 14.1 0.099 12.4 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3504) ClpS PF02617.12 EME78815.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Kei1 PF08552.6 EME78816.1 - 1.2e-47 162.0 0.6 1.6e-47 161.6 0.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 tRNA_bind PF01588.15 EME78817.1 - 1.4e-21 76.1 0.1 2.6e-20 72.0 0.0 2.8 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EME78817.1 - 9.2e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME78817.1 - 0.0009 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Med3 PF11593.3 EME78817.1 - 0.0078 15.4 5.4 0.014 14.6 3.7 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal GST_C PF00043.20 EME78817.1 - 0.032 14.2 0.8 0.1 12.6 0.0 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain K_channel_TID PF07941.6 EME78817.1 - 5.9 7.1 10.8 4.3 7.6 5.9 2.0 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CMAS PF02353.15 EME78819.1 - 6.4e-66 222.2 0.0 1.7e-64 217.5 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EME78819.1 - 1.4e-10 41.1 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME78819.1 - 8.5e-09 35.7 0.0 1.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME78819.1 - 2.2e-08 33.8 0.1 6.7e-08 32.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME78819.1 - 4.4e-08 33.7 0.0 9.8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME78819.1 - 4.5e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME78819.1 - 0.00023 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME78819.1 - 0.00049 19.7 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.12 EME78819.1 - 0.00067 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.15 EME78819.1 - 0.0042 16.1 0.0 0.0084 15.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EME78819.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EME78819.1 - 0.041 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EME78819.1 - 0.055 13.0 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 EME78819.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EME78819.1 - 0.075 11.9 0.1 0.33 9.8 0.0 2.0 2 1 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 EME78819.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase EamA PF00892.15 EME78821.1 - 0.0029 17.6 16.0 0.0051 16.8 11.1 1.5 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 EME78821.1 - 0.029 14.1 4.0 0.038 13.8 2.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EME78821.1 - 0.14 11.8 10.8 0.23 11.1 7.5 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family EmrE PF13536.1 EME78821.1 - 1.4 9.1 15.7 0.044 13.9 5.0 2.0 1 1 1 2 2 2 0 Multidrug resistance efflux transporter TFIIA_gamma_C PF02751.9 EME78822.1 - 9.2e-26 89.4 2.7 1.2e-25 88.9 1.9 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EME78822.1 - 7.2e-22 76.7 0.1 1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 EME78823.1 - 1.5e-26 92.0 22.4 1.5e-16 60.0 5.5 3.0 3 1 0 3 3 3 2 ATP synthase subunit C DNA_pol_delta_4 PF04081.8 EME78824.1 - 1.8e-24 86.3 1.5 4.5e-24 85.0 1.0 1.8 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Alpha-amylase PF00128.19 EME78825.1 - 1.1e-90 304.2 0.2 1.1e-90 304.2 0.1 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Sad1_UNC PF07738.8 EME78826.1 - 7.4e-12 45.2 0.0 2.4e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Acetyltransf_1 PF00583.19 EME78827.1 - 7.3e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME78827.1 - 3.1e-07 30.4 0.0 6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME78827.1 - 9e-06 25.5 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME78827.1 - 0.00012 22.1 0.0 0.00046 20.2 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME78827.1 - 0.0021 17.9 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EME78827.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Epimerase PF01370.16 EME78828.1 - 2.9e-48 164.3 0.0 3.8e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EME78828.1 - 1.3e-27 95.5 0.2 2.3e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EME78828.1 - 2.7e-19 68.9 0.0 5.2e-19 68.0 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EME78828.1 - 4.8e-14 51.9 0.0 2e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EME78828.1 - 6.2e-13 48.2 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EME78828.1 - 9.4e-13 48.4 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EME78828.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME78828.1 - 6.8e-09 35.0 0.0 2.3e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EME78828.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EME78828.1 - 0.0032 16.7 0.0 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family DAO PF01266.19 EME78828.1 - 0.016 14.1 0.2 0.029 13.3 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EME78828.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 EME78828.1 - 0.023 14.4 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DcpS_C PF11969.3 EME78829.1 - 2.3e-30 105.1 0.1 3.6e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EME78829.1 - 5e-26 91.2 0.0 8.2e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 EME78829.1 - 0.053 14.0 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 HIT domain 2OG-FeII_Oxy PF03171.15 EME78830.1 - 8.6e-16 58.0 0.2 1.5e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EME78830.1 - 7.1e-07 29.7 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 EME78831.1 - 2.1e-27 95.8 34.6 1.5e-26 92.9 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME78831.1 - 5.5e-06 25.2 20.7 1.2e-05 24.1 9.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MAS20 PF02064.10 EME78832.1 - 2.1e-21 76.0 0.5 5e-21 74.8 0.4 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor Amidohydro_3 PF07969.6 EME78832.1 - 0.051 12.7 0.0 0.051 12.7 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family ABA_WDS PF02496.11 EME78832.1 - 0.17 12.0 4.5 0.84 9.8 0.1 2.4 1 1 1 2 2 2 0 ABA/WDS induced protein Vps51 PF08700.6 EME78833.1 - 3.8e-16 58.6 1.5 3.8e-16 58.6 1.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 EME78833.1 - 0.0002 21.1 1.2 1.2 8.8 0.0 3.1 3 0 0 3 3 3 2 Exocyst complex component Sec5 COG2 PF06148.6 EME78833.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 F-box PF00646.28 EME78835.1 - 4e-07 29.5 0.5 2.9e-06 26.7 0.3 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EME78835.1 - 0.00054 19.6 0.2 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 EME78837.1 - 2.7e-67 227.3 0.0 3.2e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Response_reg PF00072.19 EME78838.1 - 2.7e-11 43.4 0.0 5.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EME78838.1 - 7.3e-07 29.5 0.0 2.8e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EME78838.1 - 4.8e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EME78838.1 - 0.0028 17.6 0.0 0.43 10.6 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EME78838.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain Fungal_trans_2 PF11951.3 EME78839.1 - 2.5e-45 154.7 0.5 3.5e-45 154.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78839.1 - 1.2e-06 28.3 9.2 2e-06 27.6 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EME78840.1 - 7.4e-13 48.1 0.1 1.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF202 PF02656.10 EME78841.1 - 3.3 7.9 7.4 6.6 7.0 3.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) RNase_H2_suC PF08615.6 EME78843.1 - 9.9e-24 83.7 0.4 7.2e-23 80.9 0.2 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Metallophos PF00149.23 EME78844.1 - 1.2e-43 148.8 0.9 1.5e-43 148.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box PF00646.28 EME78845.1 - 4.4e-05 23.0 0.0 8.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME78845.1 - 0.00077 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like tRNA-synt_2c PF01411.14 EME78846.1 - 2.2e-07 29.5 0.1 2.8e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EME78846.1 - 1.8e-05 24.5 0.2 3.3e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain FAD_binding_3 PF01494.14 EME78847.1 - 7.8e-14 51.4 0.2 3e-13 49.5 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EME78847.1 - 0.0099 14.8 0.9 0.061 12.2 0.6 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EME78847.1 - 0.021 13.9 0.2 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EME78847.1 - 0.078 13.0 2.3 0.13 12.3 0.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EME78847.1 - 0.082 11.5 4.2 13 4.2 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 EME78847.1 - 0.1 13.0 0.6 3.9 7.9 0.2 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME78847.1 - 0.17 11.6 2.8 1.3 8.8 0.5 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME78847.1 - 0.39 10.5 1.8 0.74 9.6 1.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME78847.1 - 1 8.1 5.3 4.4 6.1 1.7 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 EME78848.1 - 1.9e-08 33.4 25.3 1.9e-08 33.4 17.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EME78848.1 - 0.0055 16.2 1.4 0.0055 16.2 1.0 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EME78848.1 - 0.33 9.4 16.0 0.19 10.2 8.3 2.2 1 1 0 1 1 1 0 Sugar (and other) transporter PS-DH PF14765.1 EME78849.1 - 4.3e-08 32.6 0.0 1.4e-05 24.4 0.0 2.9 1 1 0 1 1 1 1 Polyketide synthase dehydratase zf-C2H2_6 PF13912.1 EME78849.1 - 0.1 12.5 0.2 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DHquinase_II PF01220.14 EME78849.1 - 0.11 11.8 0.1 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Dehydroquinase class II adh_short PF00106.20 EME78850.1 - 1.7e-06 28.0 0.1 2.1e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME78850.1 - 3.1e-06 27.1 0.1 3.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME78850.1 - 0.11 12.2 0.3 0.26 10.9 0.2 1.7 1 1 0 1 1 1 0 KR domain F-box PF00646.28 EME78851.1 - 0.092 12.4 0.1 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EME78851.1 - 0.12 12.1 0.5 0.29 10.8 0.0 2.0 2 1 0 2 2 2 0 F-box-like SUV3_C PF12513.3 EME78856.1 - 2e-16 59.1 0.6 7.4e-16 57.3 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EME78856.1 - 1.3e-08 34.5 0.0 4.8e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sec1 PF00995.18 EME78857.1 - 9.3e-133 443.8 0.0 1.1e-132 443.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.20 EME78860.1 - 0.033 13.3 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Ammonium_transp PF00909.16 EME78862.1 - 1.1e-111 373.1 21.5 1.3e-111 372.8 14.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1691 PF07950.6 EME78862.1 - 0.12 12.3 2.0 0.37 10.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) FAD_binding_1 PF00667.15 EME78863.1 - 1.3e-61 207.8 0.0 1.9e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EME78863.1 - 1.8e-33 115.5 4.5 2.1e-33 115.3 0.9 2.5 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 EME78863.1 - 1.4e-23 83.5 0.2 1.6e-22 80.1 0.1 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 EME78865.1 - 5.8e-21 73.9 0.0 2.3e-14 52.7 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME78865.1 - 2.5e-11 43.3 0.0 1.8e-06 27.8 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78865.1 - 0.0029 17.3 0.1 0.28 11.0 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOR2-PAG1_N PF14222.1 EME78866.1 - 1.6e-193 644.4 0.0 4.2e-193 643.0 0.0 1.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EME78866.1 - 2.3e-93 312.7 0.5 4.8e-93 311.6 0.3 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EME78866.1 - 4.6e-38 130.5 9.0 6.4e-13 47.2 0.0 4.2 3 1 1 4 4 4 4 Cell morphogenesis central region Glyco_hydro_47 PF01532.15 EME78867.1 - 7.7e-110 367.6 0.0 8.9e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.11 EME78868.1 - 2.4e-28 98.8 33.6 1.9e-27 95.9 23.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2961 PF11175.3 EME78869.1 - 1.2e-22 80.3 1.5 1.5e-22 80.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Ribosomal_L23 PF00276.15 EME78870.1 - 1.5e-08 34.5 0.0 4.9e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 RRM_1 PF00076.17 EME78874.1 - 8.6e-26 89.3 0.1 2.7e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME78874.1 - 1e-19 70.0 0.0 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME78874.1 - 1.2e-14 54.0 0.0 5e-07 29.6 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EME78874.1 - 0.0019 17.8 0.0 0.014 15.0 0.0 2.2 2 1 0 2 2 2 1 Calcipressin Limkain-b1 PF11608.3 EME78874.1 - 0.027 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 DUF1840 PF08895.6 EME78874.1 - 0.071 13.1 0.7 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3123 PF11321.3 EME78874.1 - 0.078 13.2 1.0 0.16 12.2 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) RRM_3 PF08777.6 EME78874.1 - 0.079 12.8 3.7 0.47 10.3 2.3 2.2 1 1 0 1 1 1 0 RNA binding motif MFS_1 PF07690.11 EME78875.1 - 1.4e-48 165.4 18.9 3.9e-44 150.8 12.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EME78875.1 - 0.00077 18.2 1.8 0.00077 18.2 1.3 1.8 2 1 0 2 2 2 1 BT1 family MFS_2 PF13347.1 EME78875.1 - 0.0034 15.8 5.5 0.0034 15.8 3.8 3.3 2 2 2 4 4 4 1 MFS/sugar transport protein MFS_1_like PF12832.2 EME78875.1 - 0.047 13.4 3.5 0.78 9.5 0.2 3.6 3 1 0 3 3 3 0 MFS_1 like family OATP PF03137.15 EME78875.1 - 0.14 10.2 5.2 1.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.14 EME78876.1 - 1.8e-21 76.6 0.0 2.1e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EME78876.1 - 1.6e-06 27.1 0.0 0.0062 15.3 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.19 EME78876.1 - 0.0025 16.7 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME78876.1 - 0.0064 16.4 0.1 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME78876.1 - 0.02 14.9 0.0 0.063 13.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME78876.1 - 0.034 14.5 0.3 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ferritin_2 PF13668.1 EME78878.1 - 1.3e-05 25.1 0.1 2.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain UNC45-central PF11701.3 EME78879.1 - 4.2e-37 127.2 4.8 6e-35 120.2 0.3 3.9 3 1 1 4 4 4 2 Myosin-binding striated muscle assembly central DUF3154 PF11351.3 EME78879.1 - 0.042 13.6 0.1 0.64 9.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) DUF2497 PF10691.4 EME78879.1 - 0.043 13.7 2.2 0.09 12.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) p450 PF00067.17 EME78880.1 - 1.2e-79 268.0 0.0 1.5e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 EME78881.1 - 0.0039 17.1 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Cyclase PF04199.8 EME78882.1 - 1.3e-12 47.7 0.1 2.7e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Putative cyclase TFIIA PF03153.8 EME78883.1 - 2.6 7.8 9.5 4.1 7.1 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HORMA PF02301.13 EME78884.1 - 6.7e-23 81.2 0.0 8.7e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 EME78885.1 - 3.7e-11 42.7 0.2 5.9e-10 38.9 0.0 3.1 2 1 1 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EME78885.1 - 1.6e-06 28.1 0.8 0.0018 18.1 0.0 4.2 4 1 0 4 4 4 2 Exportin 1-like protein UTP15_C PF09384.5 EME78885.1 - 0.049 13.3 0.1 0.86 9.2 0.0 2.6 2 1 0 2 2 2 0 UTP15 C terminal TAP42 PF04177.7 EME78887.1 - 5.8e-97 324.6 5.9 6.5e-97 324.5 4.1 1.0 1 0 0 1 1 1 1 TAP42-like family Glyco_trans_1_2 PF13524.1 EME78887.1 - 0.02 15.1 1.9 2.6 8.3 0.1 2.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 TPR_11 PF13414.1 EME78887.1 - 0.047 13.3 0.8 0.11 12.1 0.6 1.6 1 0 0 1 1 1 0 TPR repeat DUF2132 PF09905.4 EME78887.1 - 0.11 12.4 0.1 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) TPR_2 PF07719.12 EME78887.1 - 0.19 11.6 2.4 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuclease_3 PF00636.21 EME78888.1 - 1.1e-40 138.6 0.0 3.8e-21 75.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EME78888.1 - 5.9e-24 84.4 0.4 3.1e-11 43.3 0.0 4.3 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EME78888.1 - 2.7e-20 71.9 0.0 5.3e-19 67.7 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 EME78888.1 - 1.2e-14 53.9 0.0 2.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME78888.1 - 3.3e-12 46.2 0.0 1.5e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EME78888.1 - 2.3e-11 43.8 0.5 6.3e-11 42.4 0.3 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EME78888.1 - 7.5e-06 26.4 0.0 0.074 13.6 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif SNF2_N PF00176.18 EME78888.1 - 0.013 14.2 2.8 0.098 11.4 0.2 2.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EME78888.1 - 0.064 13.4 0.4 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Beta-lactamase PF00144.19 EME78889.1 - 4.5e-46 157.3 0.0 5.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EME78889.1 - 0.0012 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase MTTB PF06253.6 EME78889.1 - 0.16 9.6 0.0 0.26 8.9 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NAD_binding_10 PF13460.1 EME78890.1 - 3.1e-13 50.1 0.0 5.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME78890.1 - 2.7e-10 39.9 0.1 3.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EME78890.1 - 0.00016 21.2 0.1 0.0059 16.0 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EME78890.1 - 0.016 15.1 0.2 0.041 13.7 0.1 1.7 1 1 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.21 EME78890.1 - 0.026 14.0 0.1 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 EME78890.1 - 0.056 13.2 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.12 EME78890.1 - 0.1 11.4 0.1 0.27 10.0 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain DUF2934 PF11154.3 EME78892.1 - 0.002 17.4 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2934) Prion_bPrPp PF11587.3 EME78893.1 - 0.026 14.1 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal AA_permease_2 PF13520.1 EME78894.1 - 2.9e-81 273.1 36.7 3.7e-81 272.8 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME78894.1 - 1.4e-17 63.2 33.7 1.8e-17 62.8 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease FtsL PF04999.8 EME78894.1 - 0.93 9.2 4.0 0.45 10.2 0.1 2.6 3 1 0 3 3 3 0 Cell division protein FtsL TPR_11 PF13414.1 EME78895.1 - 5.5e-13 48.3 0.5 1.2e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EME78895.1 - 1.2e-07 31.0 0.1 0.017 14.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME78895.1 - 1.5e-06 27.6 0.0 0.072 13.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME78895.1 - 2.9e-05 23.9 0.5 5.5e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EME78895.1 - 0.0006 19.9 0.1 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIS13 PF08202.6 EME78895.1 - 0.0011 18.1 1.6 0.0012 18.0 0.8 1.4 1 1 0 1 1 1 1 Mis12-Mtw1 protein family TPR_7 PF13176.1 EME78895.1 - 0.0037 16.9 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME78895.1 - 0.0098 16.2 0.0 0.025 14.8 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME78895.1 - 0.011 15.4 0.2 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat EIAV_Rev PF11129.3 EME78895.1 - 0.038 13.9 0.1 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus FliT PF05400.8 EME78895.1 - 0.067 13.6 4.3 0.063 13.6 1.4 2.1 2 1 0 2 2 2 0 Flagellar protein FliT TPR_14 PF13428.1 EME78895.1 - 0.098 13.3 0.0 17 6.4 0.0 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME78895.1 - 0.12 12.9 0.0 36 5.1 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.6 EME78895.1 - 0.14 11.5 7.6 1.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial fission regulator PQ-loop PF04193.9 EME78897.1 - 8.6e-18 63.6 3.7 1.3e-09 37.4 0.1 3.5 4 0 0 4 4 4 2 PQ loop repeat Rhabdo_glycop PF00974.13 EME78897.1 - 0.91 7.6 3.6 1.7 6.7 2.2 1.6 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein ER_lumen_recept PF00810.13 EME78897.1 - 1.1 9.6 6.1 1 9.8 2.0 2.4 1 1 1 2 2 2 0 ER lumen protein retaining receptor IncA PF04156.9 EME78897.1 - 2.7 7.5 5.1 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 IncA protein Radical_SAM PF04055.16 EME78898.1 - 4.8e-24 85.4 0.0 8.7e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EME78898.1 - 1.5e-22 79.4 0.2 4.5e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.20 EME78898.1 - 6.2e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Clp1 PF06807.9 EME78900.1 - 9.8e-20 71.1 0.0 1.9e-19 70.1 0.0 1.4 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.12 EME78900.1 - 6.6e-05 22.5 0.0 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EME78900.1 - 0.0018 18.2 0.0 0.0066 16.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EME78900.1 - 0.0028 17.3 0.0 0.0078 15.9 0.0 1.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME78900.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EME78900.1 - 0.054 13.3 0.2 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 EME78900.1 - 0.16 11.4 0.0 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family KOW PF00467.24 EME78902.1 - 3.3e-08 32.9 1.7 8.3e-08 31.6 1.2 1.7 1 0 0 1 1 1 1 KOW motif Ost4 PF10215.4 EME78904.1 - 5.1e-16 57.8 1.9 6.4e-16 57.5 1.3 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase WD40 PF00400.27 EME78905.1 - 2.1e-23 81.2 7.1 0.00015 21.5 0.0 7.2 7 2 0 7 7 7 5 WD domain, G-beta repeat FMN_red PF03358.10 EME78907.1 - 1.3e-09 37.7 0.0 1.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EME78907.1 - 3.1e-05 23.9 0.0 6.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EME78907.1 - 7.1e-05 22.3 0.0 8.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EME78907.1 - 0.011 15.1 0.2 0.14 11.4 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin LRR_8 PF13855.1 EME78908.1 - 3.6e-05 23.4 2.3 0.11 12.2 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EME78908.1 - 0.0089 15.6 0.9 0.38 10.4 0.0 2.8 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EME78908.1 - 0.072 12.8 2.2 0.091 12.5 0.1 2.3 2 0 0 2 2 2 0 F-box-like SDA1 PF05285.7 EME78908.1 - 5.8 6.1 11.8 11 5.2 8.2 1.3 1 0 0 1 1 1 0 SDA1 XAP5 PF04921.9 EME78910.1 - 5.9e-69 232.2 0.0 7.5e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 XAP5, circadian clock regulator 2_5_RNA_ligase2 PF13563.1 EME78911.1 - 0.041 13.5 2.5 0.26 10.9 1.7 2.2 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily PAPS_reduct PF01507.14 EME78912.1 - 7.4e-27 94.2 0.0 3.6e-23 82.2 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DegS PF05384.6 EME78912.1 - 0.045 12.9 0.1 0.067 12.4 0.1 1.1 1 0 0 1 1 1 0 Sensor protein DegS MatE PF01554.13 EME78913.1 - 1.5e-57 193.7 23.4 1.8e-32 112.1 5.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EME78913.1 - 2.3e-05 24.2 23.5 4.4e-05 23.3 8.0 3.1 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain 2TM PF13239.1 EME78913.1 - 0.86 9.7 11.9 2.5 8.2 0.1 3.4 3 0 0 3 3 3 0 2TM domain Nucleoporin_FG PF13634.1 EME78914.1 - 0.00019 21.6 30.5 0.00019 21.6 21.2 3.1 2 1 1 3 3 3 2 Nucleoporin FG repeat region Lge1 PF11488.3 EME78914.1 - 0.0041 17.2 0.0 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 CHASE3 PF05227.8 EME78914.1 - 0.052 13.2 5.4 0.044 13.4 2.0 2.0 2 0 0 2 2 2 0 CHASE3 domain Laminin_II PF06009.7 EME78914.1 - 0.055 13.2 1.5 0.33 10.6 0.4 2.2 2 0 0 2 2 2 0 Laminin Domain II Glyco_hydro_18 PF00704.23 EME78918.1 - 1.2e-09 38.1 0.0 6.6e-09 35.6 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.2 EME78920.1 - 1.6e-12 47.8 0.2 1.3e-11 44.8 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME78920.1 - 4.2e-07 29.7 0.0 6.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME78920.1 - 1.7e-06 27.8 0.0 1.3e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME78920.1 - 0.0081 15.7 0.1 0.019 14.5 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EME78920.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase UPF0227 PF05728.7 EME78920.1 - 0.054 13.2 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 EME78920.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EME78920.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2684 PF10885.3 EME78921.1 - 0.25 11.1 2.1 6.9 6.6 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2684) Snf7 PF03357.16 EME78922.1 - 3.1e-17 62.4 26.8 1.5e-16 60.3 18.6 2.0 1 1 0 1 1 1 1 Snf7 TMF_DNA_bd PF12329.3 EME78923.1 - 0.092 12.5 5.9 0.26 11.1 4.1 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Beta-lactamase PF00144.19 EME78925.1 - 3.7e-34 118.2 0.0 5.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EME78925.1 - 0.058 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DAO PF01266.19 EME78926.1 - 1.2e-30 106.6 4.3 1.5e-30 106.3 3.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME78926.1 - 7.2e-05 21.9 1.8 0.00013 21.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EME78926.1 - 9.8e-05 21.3 0.1 0.00019 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME78926.1 - 0.00025 21.0 1.2 0.00086 19.2 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME78926.1 - 0.00025 20.9 0.1 0.00054 19.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME78926.1 - 0.00049 20.4 0.5 0.0016 18.7 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME78926.1 - 0.0013 17.9 1.5 0.0013 17.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EME78926.1 - 0.011 15.1 0.4 0.02 14.2 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EME78926.1 - 0.023 13.5 0.3 0.038 12.8 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EME78926.1 - 0.035 13.5 0.4 0.094 12.1 0.3 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EME78926.1 - 0.036 13.7 0.5 0.062 12.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EME78926.1 - 0.043 14.0 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EME78926.1 - 0.054 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EME78926.1 - 0.058 12.0 0.4 0.13 10.9 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EME78926.1 - 0.1 11.0 0.3 0.16 10.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EME78926.1 - 0.85 8.6 7.8 0.26 10.3 0.5 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase COPI_assoc PF08507.5 EME78927.1 - 6.7e-43 145.6 3.0 7.3e-43 145.5 2.1 1.0 1 0 0 1 1 1 1 COPI associated protein Toxin_47 PF15527.1 EME78927.1 - 0.078 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Putative toxin 47 DUF308 PF03729.8 EME78927.1 - 2.4 8.2 21.5 24 5.0 6.5 3.1 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) DUF3784 PF12650.2 EME78927.1 - 8.1 6.4 9.7 0.89 9.5 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) MS_channel PF00924.13 EME78927.1 - 8.2 5.6 8.2 1.5 8.1 1.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel GATA PF00320.22 EME78929.1 - 1.3e-30 104.4 23.7 1.9e-16 59.1 2.8 2.9 3 0 0 3 3 3 2 GATA zinc finger ArfGap PF01412.13 EME78929.1 - 1.5e-05 24.7 1.3 0.041 13.6 0.1 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.7 EME78929.1 - 1.5e-05 24.2 4.3 0.035 13.4 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 EME78929.1 - 0.00038 20.0 4.8 0.087 12.4 0.3 2.8 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EME78929.1 - 0.0019 18.1 1.9 0.6 10.1 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain RRN7 PF11781.3 EME78929.1 - 0.0062 16.0 10.2 0.17 11.4 0.5 3.2 3 0 0 3 3 3 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 EME78929.1 - 0.011 15.2 0.2 0.011 15.2 0.1 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.1 EME78929.1 - 0.013 14.6 11.1 0.42 9.8 0.9 3.3 2 2 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EME78929.1 - 0.024 14.4 15.4 0.045 13.5 0.3 3.4 2 1 1 3 3 3 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EME78929.1 - 0.045 13.4 5.2 1.3 8.6 0.4 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.7 EME78929.1 - 0.046 13.4 4.4 2.4 8.0 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.14 EME78929.1 - 0.29 10.8 7.2 0.82 9.3 0.2 3.0 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2H2_3 PF13878.1 EME78929.1 - 1.1 8.9 11.7 6.3 6.4 0.1 4.3 3 1 1 4 4 4 0 zinc-finger of acetyl-transferase ESCO Ribosomal_L32p PF01783.18 EME78929.1 - 1.6 8.9 15.2 17 5.6 1.5 4.7 3 2 0 3 3 3 0 Ribosomal L32p protein family zf-UBR PF02207.15 EME78929.1 - 6.1 6.6 9.6 0.3 10.8 0.2 2.9 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) IF-2B PF01008.12 EME78930.1 - 2.7e-46 157.8 0.0 3.6e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CorA PF01544.13 EME78932.1 - 2.8 6.9 5.4 6.8 5.6 3.7 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EME78933.1 - 1.2e-10 40.9 0.0 1.6e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Sugar_tr PF00083.19 EME78934.1 - 3.1e-40 138.1 1.0 3.6e-40 137.9 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78934.1 - 4.5e-10 38.7 0.7 5.3e-10 38.5 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FMN_dh PF01070.13 EME78935.1 - 4.8e-117 390.7 0.1 6.4e-117 390.3 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF2235 PF09994.4 EME78935.1 - 6.3e-69 232.4 0.1 1e-68 231.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ThiG PF05690.9 EME78935.1 - 0.0003 19.9 0.0 0.49 9.4 0.0 2.6 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EME78935.1 - 0.0003 19.8 0.3 0.00048 19.1 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EME78935.1 - 0.0019 17.1 1.1 0.0094 14.8 0.3 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain PcrB PF01884.12 EME78935.1 - 0.048 12.8 0.3 0.17 11.1 0.0 2.0 2 1 1 3 3 3 0 PcrB family NMO PF03060.10 EME78935.1 - 0.2 10.7 2.9 0.13 11.4 0.7 1.5 2 0 0 2 2 2 0 Nitronate monooxygenase GMC_oxred_N PF00732.14 EME78937.1 - 4.8e-25 88.3 0.0 1.7e-22 79.9 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EME78937.1 - 5.1e-21 75.4 0.0 1.2e-20 74.2 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME78937.1 - 3.2e-05 22.9 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME78937.1 - 4.1e-05 23.5 0.0 0.00013 21.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME78937.1 - 0.00023 20.2 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME78937.1 - 0.00032 20.6 0.0 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME78937.1 - 0.00087 18.2 0.0 0.0024 16.8 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME78937.1 - 0.02 14.9 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CbiA PF01656.18 EME78937.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GIDA PF01134.17 EME78937.1 - 0.074 11.9 0.0 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EME78937.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CFEM PF05730.6 EME78938.1 - 2.4e-13 49.7 10.4 4.2e-13 48.8 7.2 1.4 1 0 0 1 1 1 1 CFEM domain Coiled-coil_56 PF09813.4 EME78938.1 - 0.12 12.3 0.6 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Peroxidase_2 PF01328.12 EME78939.1 - 1.7e-12 46.6 0.1 5.8e-12 44.9 0.1 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_35 PF01301.14 EME78940.1 - 1.4e-84 284.1 0.0 2.2e-84 283.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EME78940.1 - 3.8e-55 186.0 3.0 6.1e-55 185.3 2.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EME78940.1 - 1.1e-51 173.7 11.3 9.3e-28 96.7 2.0 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EME78940.1 - 5.7e-16 57.6 0.0 1.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Sin_N PF04801.8 EME78943.1 - 9.6e-31 107.0 3.3 1e-29 103.6 2.3 2.0 1 1 0 1 1 1 1 Sin-like protein conserved region MMS1_N PF10433.4 EME78944.1 - 6.6e-84 281.8 0.0 1.4e-83 280.7 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EME78944.1 - 2.7e-75 253.4 0.0 2.6e-74 250.2 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.1 EME78944.1 - 0.014 15.6 6.0 33 4.9 0.0 5.8 6 0 0 6 6 6 0 PQQ-like domain HET PF06985.6 EME78945.1 - 1.6e-20 73.6 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.3 EME78946.1 - 7.1e-38 130.4 0.0 8.9e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_4 PF01565.18 EME78947.1 - 6.5e-28 96.9 0.2 1.2e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME78947.1 - 9.7e-09 35.0 0.1 1.9e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like OB_NTP_bind PF07717.11 EME78948.1 - 2.9e-28 97.9 0.0 6.6e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME78948.1 - 6e-22 77.5 0.3 1.6e-21 76.1 0.2 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME78948.1 - 4.4e-11 42.4 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME78948.1 - 2.9e-07 30.1 0.3 6.2e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME78948.1 - 7.5e-06 26.1 0.2 2.5e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EME78948.1 - 0.0001 21.7 0.1 0.00048 19.6 0.1 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EME78948.1 - 0.0028 17.5 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EME78948.1 - 0.0065 16.2 0.1 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EME78948.1 - 0.016 14.0 0.0 0.039 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EME78948.1 - 0.02 14.8 0.0 0.067 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EME78948.1 - 0.07 11.9 0.0 0.29 9.9 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain ABC_tran PF00005.22 EME78948.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EME78948.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EME78948.1 - 0.1 11.8 0.0 0.43 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Peptidase_M20 PF01546.23 EME78948.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 AAA_29 PF13555.1 EME78948.1 - 0.14 11.7 0.3 0.63 9.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DDHD PF02862.12 EME78949.1 - 0.065 13.0 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF1573 PF07610.6 EME78949.1 - 0.09 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) TUG-UBL1 PF11470.3 EME78950.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF4385 PF14328.1 EME78951.1 - 5.4e-48 162.5 1.3 9.6e-48 161.7 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) RALF PF05498.6 EME78954.1 - 6.5e-14 52.5 1.8 8.7e-14 52.0 1.3 1.2 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) UBA_3 PF09288.5 EME78954.1 - 0.068 12.7 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Metallophos PF00149.23 EME78955.1 - 5.2e-37 127.1 0.2 6.7e-32 110.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME78955.1 - 0.00035 20.4 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ion_trans PF00520.26 EME78956.1 - 3.4e-07 29.6 25.8 4.7e-06 25.9 17.9 2.4 1 1 0 1 1 1 1 Ion transport protein Fungal_trans PF04082.13 EME78957.1 - 4e-20 71.7 0.0 1.2e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78957.1 - 4.1e-05 23.3 7.6 4.1e-05 23.3 5.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.14 EME78958.1 - 2.5e-14 53.8 0.0 6.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME78958.1 - 0.0039 16.5 0.9 3.4 6.9 0.0 2.9 1 1 1 2 2 2 2 Peptidase C65 Otubain CUE PF02845.11 EME78958.1 - 0.0089 15.5 0.1 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 EME78958.1 - 0.029 14.1 0.9 0.083 12.7 0.2 2.0 2 0 0 2 2 2 0 UBA/TS-N domain DUF605 PF04652.11 EME78958.1 - 1.7 7.9 21.6 2.6 7.3 14.9 1.3 1 0 0 1 1 1 0 Vta1 like IPK PF03770.11 EME78959.1 - 7.3e-57 192.1 0.0 1.7e-56 191.0 0.0 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase VIT1 PF01988.14 EME78959.1 - 2.3 7.6 3.0 0.98 8.8 0.4 1.5 2 0 0 2 2 2 0 VIT family ABC_tran PF00005.22 EME78960.1 - 2.1e-19 70.2 0.0 1.9e-09 37.9 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME78960.1 - 4.5e-06 26.8 0.9 0.16 11.8 0.0 3.2 3 0 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 EME78960.1 - 0.00081 19.2 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EME78960.1 - 0.044 14.1 1.7 0.084 13.1 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EME78960.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EME78960.1 - 0.13 13.1 0.8 0.5 11.1 0.2 2.5 2 2 1 3 3 3 0 AAA domain AAA_13 PF13166.1 EME78960.1 - 0.29 9.5 0.0 0.55 8.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Het-C PF07217.6 EME78961.1 - 9e-274 909.2 0.0 1.1e-273 909.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C BCS1_N PF08740.6 EME78961.1 - 0.036 13.6 0.0 0.84 9.2 0.0 2.2 2 0 0 2 2 2 0 BCS1 N terminal Helitron_like_N PF14214.1 EME78961.1 - 0.15 11.8 0.1 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Mito_carr PF00153.22 EME78962.1 - 1.1e-66 220.5 2.2 2.2e-24 84.9 0.1 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EME78962.1 - 4.2e-21 74.8 4.4 5.8e-10 39.1 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME78962.1 - 6.7e-21 71.9 4.2 1.2e-05 24.2 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EME78962.1 - 1.2e-16 58.9 5.3 0.00028 20.5 0.4 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EME78962.1 - 5.4e-12 44.4 8.3 0.0034 16.6 0.6 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EME78962.1 - 3.5e-11 42.5 4.2 0.00017 21.1 0.1 3.8 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EME78962.1 - 1.9e-08 34.3 0.3 0.00092 19.2 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EME78962.1 - 0.00016 21.3 1.7 0.51 10.1 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EME78962.1 - 0.033 13.8 2.4 5 6.8 0.0 3.6 3 1 0 3 3 3 0 EF hand OPT PF03169.10 EME78963.1 - 3.3e-130 435.4 50.6 3.8e-130 435.2 35.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_MA_2 PF13485.1 EME78964.1 - 9.4e-07 28.9 0.3 1.8e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EME78964.1 - 2.5e-05 24.2 2.0 0.00028 20.8 0.1 2.4 2 0 0 2 2 2 1 M61 glycyl aminopeptidase DUF3633 PF12315.3 EME78964.1 - 0.049 12.9 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Peptidase_S10 PF00450.17 EME78965.1 - 1.2e-61 209.1 0.0 1.4e-61 208.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ribosomal_S14 PF00253.16 EME78966.1 - 0.027 13.8 0.3 0.057 12.8 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e FAD_binding_3 PF01494.14 EME78969.1 - 9.7e-18 64.3 5.1 4.2e-17 62.2 3.5 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME78969.1 - 1.1e-06 27.8 0.5 0.02 13.8 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EME78969.1 - 0.00025 20.2 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME78969.1 - 0.00027 20.9 0.3 0.0013 18.6 0.2 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME78969.1 - 0.00049 19.1 0.1 0.41 9.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EME78969.1 - 0.00049 20.2 0.8 0.0054 16.8 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME78969.1 - 0.00056 18.6 0.3 0.42 9.1 0.3 3.2 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.5 EME78969.1 - 0.00076 18.3 0.0 0.001 17.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EME78969.1 - 0.0031 17.3 0.2 0.31 10.8 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME78969.1 - 0.0083 16.0 2.7 0.012 15.4 0.9 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME78969.1 - 0.016 15.6 0.4 0.85 10.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME78969.1 - 0.033 13.0 2.2 0.041 12.7 0.9 1.6 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_N PF00732.14 EME78969.1 - 0.15 11.2 0.1 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase Peptidase_M28 PF04389.12 EME78970.1 - 4.4e-34 117.7 0.0 7.5e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME78970.1 - 2.3e-16 59.3 0.0 6e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EME78970.1 - 0.0037 16.0 0.0 0.025 13.3 0.0 2.1 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 EME78970.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Aldedh PF00171.17 EME78971.1 - 6.7e-135 449.9 1.7 7.8e-135 449.7 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME78971.1 - 0.1 11.2 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) HVSL PF09749.4 EME78972.1 - 1.1e-68 230.8 0.0 1.2e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 EME78973.1 - 4.6e-08 33.6 1.5 6.1e-08 33.2 0.0 1.9 3 0 0 3 3 3 1 Pal1 cell morphology protein zf-C2H2 PF00096.21 EME78974.1 - 1.1e-05 25.5 3.6 0.00025 21.2 0.4 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME78974.1 - 8.7e-05 22.6 0.2 0.00024 21.2 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME78974.1 - 0.00062 19.9 3.4 0.013 15.8 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger Syncollin PF15138.1 EME78975.1 - 0.046 13.6 0.1 0.62 9.9 0.0 2.2 1 1 1 2 2 2 0 Syncollin F_actin_cap_B PF01115.12 EME78976.1 - 3e-97 324.5 0.0 3.4e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit GDI PF00996.13 EME78979.1 - 1.4e-182 606.9 0.0 1.6e-182 606.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor zf-RING_2 PF13639.1 EME78980.1 - 4.5e-14 52.0 6.0 6.8e-14 51.4 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME78980.1 - 1.8e-08 34.3 0.8 3.7e-08 33.3 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME78980.1 - 3.7e-08 32.9 2.2 5.9e-08 32.2 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME78980.1 - 5e-07 29.6 4.2 8e-07 28.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME78980.1 - 1.9e-06 27.4 3.1 3e-06 26.8 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME78980.1 - 2.7e-05 23.7 1.8 4.2e-05 23.1 1.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME78980.1 - 0.00041 20.1 1.6 0.00081 19.1 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME78980.1 - 0.012 15.1 6.1 0.022 14.3 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EME78980.1 - 0.038 13.6 5.3 0.067 12.8 3.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EME78980.1 - 0.1 12.4 3.9 0.21 11.4 2.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EME78980.1 - 0.17 11.9 4.4 0.3 11.1 3.0 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME78980.1 - 0.36 10.8 2.6 1 9.3 1.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain HEAT_EZ PF13513.1 EME78980.1 - 0.66 10.5 4.8 2.4 8.7 0.1 3.2 3 0 0 3 3 3 0 HEAT-like repeat Prok-RING_1 PF14446.1 EME78980.1 - 0.97 9.2 8.3 0.065 12.9 1.0 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 adh_short_C2 PF13561.1 EME78983.1 - 2.2e-21 76.7 0.0 5.3e-16 59.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME78983.1 - 7e-19 68.3 0.4 7.2e-09 35.7 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EME78983.1 - 2.4e-08 33.8 0.2 1.2e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EME78983.1 - 1.3e-06 27.3 0.2 1.9e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME78983.1 - 0.0063 15.9 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 EME78983.1 - 0.016 15.4 0.0 0.023 14.9 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EME78983.1 - 0.025 14.4 0.0 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EME78983.1 - 0.03 13.9 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EME78983.1 - 0.039 12.8 0.0 0.073 11.9 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 EME78983.1 - 0.044 12.9 0.0 0.092 11.8 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EME78983.1 - 0.049 13.6 0.1 0.089 12.7 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding EFhand_Ca_insen PF08726.5 EME78983.1 - 0.07 13.1 0.1 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Ca2+ insensitive EF hand TrkA_N PF02254.13 EME78983.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EME78983.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EME78984.1 - 6e-11 41.7 0.1 9.9e-11 40.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME78984.1 - 5.7e-07 29.3 9.1 9.3e-07 28.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 EME78984.1 - 0.0022 17.5 0.6 0.006 16.2 0.4 1.7 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension HCV_NS4b PF01001.14 EME78984.1 - 0.0054 16.1 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein NS4b DUF4140 PF13600.1 EME78984.1 - 0.11 13.0 0.6 8.2 6.9 0.1 2.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sugar_tr PF00083.19 EME78985.1 - 2.8e-94 316.2 20.3 3.4e-94 315.9 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME78985.1 - 2.5e-25 88.9 21.5 2.5e-25 88.9 14.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME78985.1 - 0.00048 18.4 1.8 0.0013 17.0 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.14 EME78986.1 - 1.3e-26 92.9 0.2 3.3e-23 81.7 0.1 2.5 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME78986.1 - 4.7e-26 92.1 0.5 9.6e-25 87.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME78986.1 - 1.3e-14 53.9 0.6 2.4e-11 43.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME78986.1 - 8.5e-14 51.9 0.1 7e-06 26.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME78986.1 - 4.9e-12 46.0 0.7 0.00081 19.7 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EME78986.1 - 2.2e-08 33.4 1.1 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EME78986.1 - 4.4e-08 32.5 5.7 0.00025 20.2 1.2 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EME78986.1 - 3.8e-07 30.0 0.1 0.0001 22.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME78986.1 - 4.3e-07 29.8 2.2 0.3 10.8 0.0 3.4 2 1 1 3 3 3 3 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME78986.1 - 1.1e-05 24.6 0.1 0.04 12.8 0.0 3.8 4 0 0 4 4 4 1 Lycopene cyclase protein IlvN PF07991.7 EME78986.1 - 3.2e-05 23.3 0.1 0.0052 16.1 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_2 PF00890.19 EME78986.1 - 4.1e-05 22.5 1.9 0.016 14.0 1.5 3.1 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EME78986.1 - 0.00011 20.8 1.0 0.029 12.8 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 EME78986.1 - 0.00012 21.1 6.9 0.088 11.6 0.4 4.0 3 1 0 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EME78986.1 - 0.00018 21.6 0.1 0.54 10.3 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EME78986.1 - 0.00021 21.0 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME78986.1 - 0.00023 20.7 0.2 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EME78986.1 - 0.00061 18.7 1.1 1.1 8.0 0.0 3.3 3 0 0 3 3 3 1 Glucose inhibited division protein A F420_oxidored PF03807.12 EME78986.1 - 0.00089 19.6 0.1 5.5 7.4 0.0 3.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME78986.1 - 0.0013 18.6 0.9 0.2 11.6 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain Thi4 PF01946.12 EME78986.1 - 0.0018 17.3 1.8 0.29 10.2 0.0 3.3 4 0 0 4 4 4 1 Thi4 family NAD_binding_7 PF13241.1 EME78986.1 - 0.0047 17.1 0.0 0.36 11.1 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding ApbA PF02558.11 EME78986.1 - 0.0048 16.3 0.1 0.64 9.4 0.0 3.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EME78986.1 - 0.019 14.5 0.5 0.039 13.5 0.3 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.10 EME78986.1 - 0.031 14.1 0.3 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EME78986.1 - 0.046 13.5 1.7 0.58 9.9 0.1 2.6 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 EME78986.1 - 0.38 10.7 3.1 2.6 7.9 0.2 2.5 3 0 0 3 3 2 0 NADH(P)-binding Methyltransf_11 PF08241.7 EME78987.1 - 2.2e-19 69.7 0.0 3.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME78987.1 - 9.8e-14 51.8 0.0 2.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME78987.1 - 2.6e-11 43.7 0.1 4.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME78987.1 - 3.4e-10 39.6 0.0 5.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME78987.1 - 9.8e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME78987.1 - 1.4e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME78987.1 - 2.1e-08 33.5 0.0 3.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME78987.1 - 1.2e-05 25.3 0.0 3.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EME78987.1 - 0.0071 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 EME78987.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EME78987.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EME78987.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.7 EME78987.1 - 0.16 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Astacin PF01400.19 EME78990.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) DUF4396 PF14342.1 EME78991.1 - 3.2e-21 75.8 11.8 3.2e-21 75.8 8.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) adh_short PF00106.20 EME78992.1 - 2.5e-16 60.0 0.4 4.2e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME78992.1 - 6.8e-08 32.3 0.3 1.2e-07 31.5 0.2 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME78992.1 - 2.6e-07 30.8 0.2 4.2e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME78992.1 - 2.9e-05 23.6 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME78992.1 - 8.2e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 EME78992.1 - 0.027 13.4 0.0 0.33 9.8 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein YjeF_N PF03853.10 EME78992.1 - 0.028 14.0 0.8 0.31 10.6 0.1 2.4 2 1 0 3 3 3 0 YjeF-related protein N-terminus ChuX_HutX PF06228.8 EME78992.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX MARVEL PF01284.18 EME78993.1 - 0.1 12.3 0.3 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Membrane-associating domain Peptidase_M20 PF01546.23 EME78994.1 - 2.2e-15 56.6 1.6 9.5e-15 54.5 1.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EME78994.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 M20_dimer PF07687.9 EME78994.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Aminotran_1_2 PF00155.16 EME78995.1 - 1.9e-82 277.1 0.0 2.1e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tricorn_C1 PF14684.1 EME78995.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease C1 domain Syntaxin-18_N PF10496.4 EME78996.1 - 6.5e-08 32.3 3.8 1.7e-06 27.7 0.0 3.9 2 2 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EME78996.1 - 5.6e-05 22.7 5.6 0.00011 21.7 2.0 2.7 2 0 0 2 2 2 1 SNARE domain BRX PF08381.6 EME78996.1 - 0.058 12.4 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 CMV_1a PF12467.3 EME78996.1 - 0.45 10.8 5.6 1 9.7 3.9 1.6 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Spore_II_R PF09551.5 EME78996.1 - 1.1 9.3 3.9 1.1 9.3 0.7 2.3 1 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) DUF16 PF01519.11 EME78996.1 - 1.3 9.2 11.1 0.26 11.4 3.2 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 PAS_9 PF13426.1 EME78998.1 - 2.5e-09 37.4 0.0 8.3e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EME78998.1 - 8.8e-08 32.1 0.0 5.1e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EME78998.1 - 8.8e-06 25.7 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EME78998.1 - 0.00012 21.9 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EME78998.1 - 0.00014 21.6 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold DUF448 PF04296.8 EME78998.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF448) WD40 PF00400.27 EME79000.1 - 3.1e-16 58.5 6.2 2.5e-08 33.4 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Mob1_phocein PF03637.12 EME79001.1 - 1.2e-24 86.9 0.2 2.6e-24 85.8 0.1 1.4 1 1 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EME79002.1 - 2.3e-44 150.9 0.1 3.1e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EME79002.1 - 0.00042 19.9 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.1 EME79002.1 - 0.00065 20.0 0.1 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME79002.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ArgK PF03308.11 EME79002.1 - 0.0066 15.2 0.3 0.69 8.6 0.0 2.7 3 0 0 3 3 3 1 ArgK protein AAA_22 PF13401.1 EME79002.1 - 0.01 15.9 0.5 0.072 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EME79002.1 - 0.01 15.7 0.2 0.023 14.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EME79002.1 - 0.012 15.9 0.3 0.034 14.4 0.0 1.9 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 EME79002.1 - 0.017 15.4 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 EME79002.1 - 0.018 14.7 0.1 0.046 13.4 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 EME79002.1 - 0.019 14.4 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EME79002.1 - 0.023 14.6 0.0 0.067 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF2791 PF10923.3 EME79002.1 - 0.023 13.3 0.0 0.041 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ATP_bind_1 PF03029.12 EME79002.1 - 0.048 13.1 0.3 0.49 9.8 0.2 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EME79002.1 - 0.076 12.9 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME79002.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EME79002.1 - 0.086 12.0 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EME79002.1 - 0.11 11.4 0.3 6.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.9 EME79002.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-H2C2_2 PF13465.1 EME79003.1 - 4.2e-10 39.4 15.9 1.2e-05 25.3 2.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EME79003.1 - 4.1e-08 33.1 13.5 0.0013 18.9 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME79003.1 - 1.2e-05 25.2 12.7 0.014 15.6 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME79003.1 - 0.63 10.2 3.2 0.28 11.3 0.4 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ECM11 PF15463.1 EME79004.1 - 1e-33 116.5 0.5 1e-33 116.5 0.3 3.7 3 2 1 4 4 4 1 Extracellular mutant protein 11 F-box-like PF12937.2 EME79005.1 - 0.0055 16.3 0.4 0.0055 16.3 0.3 2.3 3 0 0 3 3 3 1 F-box-like DUF718 PF05336.8 EME79006.1 - 1.2e-34 118.2 0.1 1.4e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Xan_ur_permease PF00860.15 EME79007.1 - 4.2e-40 137.4 18.1 8.9e-40 136.3 12.5 1.5 1 1 0 1 1 1 1 Permease family Peptidase_M1 PF01433.15 EME79012.1 - 2.2e-72 244.3 0.0 2.9e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EME79012.1 - 4.6e-41 139.7 0.0 7.5e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EME79012.1 - 5.6e-18 65.2 0.1 1.2e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Lipoprotein_5 PF01298.13 EME79012.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Transferrin binding protein-like solute binding protein Peptidase_M61 PF05299.7 EME79012.1 - 0.17 11.8 2.4 0.92 9.4 1.6 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase FAM176 PF14851.1 EME79013.1 - 0.41 10.3 4.1 0.77 9.4 2.8 1.4 1 0 0 1 1 1 0 FAM176 family LIN37 PF15306.1 EME79013.1 - 0.81 9.6 6.0 1.6 8.7 4.1 1.5 1 0 0 1 1 1 0 LIN37 Sigma70_ner PF04546.8 EME79013.1 - 0.88 9.1 7.8 1.1 8.7 5.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EME79013.1 - 1 8.8 9.5 1.4 8.4 6.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EME79013.1 - 1.8 7.6 6.5 2.3 7.3 4.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 EME79013.1 - 1.9 6.4 4.1 2.1 6.2 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EME79013.1 - 3.3 5.9 9.6 4 5.7 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 EME79013.1 - 5.5 7.3 11.0 0.33 11.2 4.1 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GxGYxYP PF14323.1 EME79014.1 - 1.6e-86 290.9 0.8 2.7e-59 201.1 0.0 2.1 2 0 0 2 2 2 2 GxGYxY sequence motif in domain of unknown function CoA_binding_2 PF13380.1 EME79015.1 - 1.6e-22 79.8 0.0 2.1e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HIT PF01230.18 EME79016.1 - 6.5e-24 84.3 0.4 1.1e-23 83.6 0.3 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EME79016.1 - 5.1e-08 33.1 0.1 7.9e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EME79016.1 - 0.00021 20.9 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DNA_pol_viral_N PF00242.12 EME79017.1 - 0.38 9.7 3.8 0.5 9.3 2.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Pkinase PF00069.20 EME79018.1 - 7.8e-12 44.8 0.0 1.6e-11 43.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79018.1 - 5e-08 32.3 0.0 6.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EME79019.1 - 4.4e-12 45.9 0.7 3.7e-09 36.5 0.5 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EME79019.1 - 1.2e-09 37.1 2.1 0.0012 18.5 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EME79019.1 - 2.2e-08 32.8 3.4 0.017 14.4 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EME79019.1 - 7.9e-08 32.1 0.0 0.00049 19.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EME79019.1 - 1.5e-06 27.6 2.2 0.00025 20.5 0.2 3.3 2 1 1 3 3 3 1 EF-hand domain pair UPF0154 PF03672.8 EME79019.1 - 0.11 12.0 0.1 0.47 10.1 0.0 2.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DED PF01335.16 EME79019.1 - 0.18 11.9 0.5 8.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Death effector domain Methyltransf_16 PF10294.4 EME79020.1 - 1.3e-15 57.2 0.0 1.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EME79020.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.18 EME79021.1 - 1e-15 58.1 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME79021.1 - 0.00014 21.2 0.1 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EME79021.1 - 0.00085 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EME79021.1 - 0.0013 17.8 0.0 0.0096 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EME79021.1 - 0.019 14.0 0.0 0.091 11.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box PF00505.14 EME79021.1 - 0.076 13.2 1.7 13 6.1 0.1 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box EcKinase PF02958.15 EME79021.1 - 0.14 11.2 0.1 0.67 9.0 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase AMP-binding PF00501.23 EME79022.1 - 3.9e-82 275.8 0.0 5.9e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME79022.1 - 0.0018 19.2 0.0 0.0094 16.8 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IgG_binding_B PF01378.12 EME79022.1 - 0.04 13.7 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 B domain Pribosyltran PF00156.22 EME79023.1 - 2.1e-15 56.5 1.7 6.9e-15 54.8 1.2 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME79023.1 - 0.053 12.7 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HET PF06985.6 EME79024.1 - 1.9e-35 122.0 1.5 2.2e-35 121.8 1.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) dUTPase PF00692.14 EME79025.1 - 6.6e-23 80.5 0.1 1.5e-17 63.3 0.0 2.2 1 1 1 2 2 2 2 dUTPase gpD PF02925.11 EME79025.1 - 1.5e-07 31.2 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage scaffolding protein D ADH_zinc_N PF00107.21 EME79026.1 - 8.9e-28 96.4 0.0 1.3e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME79026.1 - 2.6e-13 50.9 0.0 5.3e-13 49.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME79026.1 - 0.00021 20.8 0.1 0.00033 20.2 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EME79026.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain ELFV_dehydrog PF00208.16 EME79026.1 - 0.035 13.6 0.1 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Peptidase_U32 PF01136.14 EME79026.1 - 0.062 12.2 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 NAD_kinase PF01513.16 EME79026.1 - 0.084 11.6 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase HalX PF08663.5 EME79028.1 - 0.24 11.3 4.0 0.16 11.9 0.3 2.5 2 0 0 2 2 2 0 HalX domain Methyltransf_31 PF13847.1 EME79029.1 - 2.5e-17 62.8 0.0 3.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME79029.1 - 2.5e-15 56.7 0.0 7.3e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME79029.1 - 3.4e-15 56.6 0.0 5.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME79029.1 - 1e-14 54.7 0.0 1.8e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME79029.1 - 3.9e-12 46.4 0.0 8.8e-12 45.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME79029.1 - 2.7e-09 36.9 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME79029.1 - 9.2e-09 34.8 0.0 1.8e-08 33.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EME79029.1 - 2.1e-08 33.4 0.0 4.1e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EME79029.1 - 8.3e-07 29.0 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME79029.1 - 1.7e-06 27.7 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EME79029.1 - 2.6e-06 26.6 0.0 3.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EME79029.1 - 2.9e-05 23.3 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 EME79029.1 - 0.00025 19.8 0.0 0.00041 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EME79029.1 - 0.00035 19.7 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EME79029.1 - 0.00063 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EME79029.1 - 0.0032 16.9 0.0 0.019 14.3 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.8 EME79029.1 - 0.0033 16.5 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 EME79029.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF1708 PF08101.6 EME79030.1 - 2e-140 468.3 0.0 2.7e-140 467.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3140 PF11338.3 EME79031.1 - 5.7e-19 68.0 0.3 6.3e-19 67.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Fungal_trans PF04082.13 EME79032.1 - 1e-31 109.7 0.7 1.6e-31 109.1 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79032.1 - 0.00092 19.0 11.0 0.002 17.9 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavodoxin_1 PF00258.20 EME79033.1 - 1.3e-12 47.9 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EME79033.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EME79033.1 - 5.1e-07 29.3 0.0 6.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EME79033.1 - 0.021 14.1 0.2 0.11 11.7 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin Flavodoxin_5 PF12724.2 EME79033.1 - 0.024 14.6 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain DUF4187 PF13821.1 EME79034.1 - 2.1e-17 62.4 3.1 6.5e-17 60.8 2.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EME79034.1 - 5.7e-12 45.2 1.5 1.1e-11 44.3 1.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EME79034.1 - 4.5e-05 23.2 8.1 0.00039 20.1 2.3 2.9 2 0 0 2 2 2 2 DExH-box splicing factor binding site DUF3024 PF11225.3 EME79034.1 - 0.075 12.9 0.3 0.19 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) ORC3_N PF07034.6 EME79035.1 - 5.8e-22 78.0 0.2 1.9e-21 76.3 0.1 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus adh_short PF00106.20 EME79036.1 - 2.7e-19 69.6 0.0 4.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME79036.1 - 4.3e-15 56.1 0.0 7.5e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME79036.1 - 8.4e-09 35.3 0.0 4.6e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME79036.1 - 0.0016 17.8 0.0 0.0034 16.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME79036.1 - 0.075 13.0 0.0 0.34 10.9 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding SNase PF00565.12 EME79037.1 - 8.8e-26 90.2 0.1 1.4e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MTP18 PF10558.4 EME79038.1 - 3e-68 228.4 0.2 3.8e-68 228.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EME79039.1 - 1.3e-25 89.2 0.3 1.4e-25 89.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF1206 PF06724.6 EME79039.1 - 0.1 12.3 0.2 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) PP2C PF00481.16 EME79040.1 - 1.3e-06 28.0 0.0 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EME79040.1 - 0.00019 20.8 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME79040.1 - 0.027 14.1 0.2 0.092 12.4 0.2 1.9 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Na_Ca_ex PF01699.19 EME79041.1 - 6.7e-41 139.1 27.4 1.7e-23 82.7 4.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TMEM173 PF15009.1 EME79041.1 - 0.13 11.0 0.1 0.25 10.1 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 173 Sec63 PF02889.11 EME79042.1 - 1.7e-192 638.4 0.3 1.3e-108 362.9 0.0 3.1 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 EME79042.1 - 1.7e-49 167.5 0.2 2.2e-28 98.8 0.1 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EME79042.1 - 3.1e-13 49.9 0.0 1.1e-07 31.8 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME79042.1 - 1.7e-10 40.6 0.0 7e-10 38.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME79042.1 - 2.1e-07 31.1 0.1 0.0018 18.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EME79042.1 - 1.6e-05 23.9 0.0 0.15 10.9 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.11 EME79042.1 - 5.9e-05 22.3 0.0 0.032 13.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_10 PF12846.2 EME79042.1 - 0.0035 16.8 2.0 5.5 6.3 0.0 4.2 6 0 0 6 6 6 2 AAA-like domain UvrD-helicase PF00580.16 EME79042.1 - 0.0089 15.3 0.0 1.8 7.8 0.0 2.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EME79042.1 - 0.019 14.7 0.0 1.1 9.0 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EME79042.1 - 0.02 15.2 3.9 4.7 7.4 0.0 3.8 4 0 0 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.1 EME79042.1 - 0.094 12.7 0.1 9 6.3 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain ChaC PF04752.7 EME79043.1 - 4.7e-41 140.6 0.0 6.2e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein SUKH-4 PF14435.1 EME79043.1 - 0.12 12.0 0.1 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 SUKH-4 immunity protein AA_kinase PF00696.23 EME79044.1 - 1.1e-39 136.3 1.0 1.7e-39 135.7 0.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EME79044.1 - 2.2e-15 56.1 0.3 5.9e-15 54.7 0.2 1.8 1 0 0 1 1 1 1 PUA domain Aldolase_II PF00596.16 EME79046.1 - 6.6e-42 143.1 0.2 2.9e-41 141.0 0.1 1.8 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain VWA PF00092.23 EME79047.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Arylsulfotran_2 PF14269.1 EME79048.1 - 1.3e-40 139.4 0.0 1.5e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME79048.1 - 9.8e-09 34.2 0.1 7.9e-08 31.2 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Glyco_hydro_35 PF01301.14 EME79049.1 - 1.2e-78 264.6 1.0 1.9e-78 264.0 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EME79049.1 - 4e-45 153.4 4.1 7.7e-45 152.4 2.8 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EME79049.1 - 5.7e-40 136.0 0.9 5e-19 68.6 0.1 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EME79049.1 - 1.4e-19 69.2 0.0 3.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 MarR_2 PF12802.2 EME79050.1 - 0.063 12.9 0.8 1.7 8.3 0.0 2.7 2 1 0 2 2 2 0 MarR family TrmB PF01978.14 EME79050.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF939_C PF11728.3 EME79052.1 - 0.0016 18.2 1.2 0.0025 17.6 0.8 1.3 1 0 0 1 1 1 1 DUF939 C-terminal domain FliD_C PF07195.7 EME79052.1 - 0.053 12.8 0.8 0.076 12.3 0.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Phage_GPO PF05929.6 EME79052.1 - 0.22 10.7 1.2 0.33 10.1 0.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AflR PF08493.5 EME79053.1 - 3.3e-14 52.5 8.6 3.3e-14 52.5 5.9 2.1 1 1 1 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EME79053.1 - 1.6e-08 34.3 9.8 4.5e-08 32.8 6.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EME79056.1 - 2.6e-70 236.7 0.0 2.8e-69 233.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EME79056.1 - 5e-52 177.2 0.2 4.7e-51 174.0 0.1 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EME79056.1 - 2.5e-32 111.2 0.8 6e-32 109.9 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EME79056.1 - 3e-09 37.0 0.2 7e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EME79056.1 - 0.00012 21.1 0.1 0.00056 18.9 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EME79056.1 - 0.027 14.2 0.0 0.098 12.4 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lactamase_B PF00753.22 EME79057.1 - 1e-21 77.5 1.5 1.4e-21 77.0 1.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME79057.1 - 3.5e-06 26.7 1.3 6.6e-06 25.8 0.9 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME79057.1 - 0.011 15.5 0.4 0.034 13.8 0.3 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF1772 PF08592.6 EME79058.1 - 1.2e-25 89.9 1.5 1.4e-25 89.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4234 PF14018.1 EME79058.1 - 0.1 12.3 1.8 0.25 11.0 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Cytochrom_C_asm PF01578.15 EME79058.1 - 0.13 11.7 4.9 1 8.8 0.8 2.0 1 1 1 2 2 2 0 Cytochrome C assembly protein EthD PF07110.6 EME79059.1 - 2.7e-19 69.8 0.1 3.7e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 EME79060.1 - 1.2e-37 129.5 51.1 1.2e-37 129.5 35.4 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME79060.1 - 2.2e-09 36.4 39.4 5.3e-07 28.5 10.6 3.6 3 1 0 4 4 4 2 Sugar (and other) transporter COX16 PF14138.1 EME79060.1 - 0.081 13.1 3.0 0.098 12.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF106 PF01956.11 EME79060.1 - 0.29 10.6 6.3 1.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Integral membrane protein DUF106 COX14 PF14880.1 EME79060.1 - 0.65 9.6 0.0 0.65 9.6 0.0 2.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly p450 PF00067.17 EME79061.1 - 5.4e-29 101.0 0.0 1.3e-28 99.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EME79063.1 - 1.1e-46 158.9 0.0 1.2e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EME79064.1 - 5e-39 133.8 0.2 5.7e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME79064.1 - 4.4e-18 65.5 0.1 5.4e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME79064.1 - 3.4e-14 53.2 0.1 4.2e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME79064.1 - 4e-05 23.1 0.1 0.00015 21.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME79064.1 - 0.00053 20.0 0.9 0.0012 18.8 0.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EME79064.1 - 0.0013 18.5 0.4 0.0026 17.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EME79064.1 - 0.0048 16.1 0.2 0.0072 15.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family THF_DHG_CYH_C PF02882.14 EME79064.1 - 0.025 13.6 0.0 0.058 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EME79064.1 - 0.037 14.1 0.2 0.073 13.1 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3432 PF11914.3 EME79064.1 - 0.041 13.9 0.6 0.074 13.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Polysacc_synt_2 PF02719.10 EME79064.1 - 0.043 12.7 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldo_ket_red PF00248.16 EME79065.1 - 6.3e-61 205.6 0.0 8e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HOOK PF05622.7 EME79065.1 - 0.011 13.6 0.3 0.015 13.1 0.2 1.1 1 0 0 1 1 1 0 HOOK protein Lipoprotein_Ltp PF07553.6 EME79065.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein Fungal_trans PF04082.13 EME79066.1 - 1.9e-12 46.6 0.5 1.9e-12 46.6 0.4 2.6 2 2 0 2 2 2 2 Fungal specific transcription factor domain NPL4 PF05021.10 EME79067.1 - 1.6e-118 395.3 0.0 2.1e-118 394.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EME79067.1 - 1.4e-72 242.1 1.6 2.1e-72 241.5 1.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EME79067.1 - 0.053 13.7 0.0 0.33 11.2 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 EME79068.1 - 7.6e-73 243.9 1.6 8.6e-73 243.7 1.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 CstA PF02554.9 EME79068.1 - 0.097 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA F-box-like PF12937.2 EME79069.1 - 0.00055 19.6 0.0 0.0023 17.6 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EME79069.1 - 1.3 8.8 4.4 22 4.8 0.7 3.2 3 0 0 3 3 3 0 F-box domain DUF4246 PF14033.1 EME79070.1 - 1.1e-175 585.0 0.1 1.3e-175 584.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EME79070.1 - 0.0002 21.6 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase NMO PF03060.10 EME79073.1 - 3.2e-71 240.1 0.9 4e-71 239.8 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EME79073.1 - 4.8e-10 38.8 1.7 5.3e-10 38.7 0.3 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EME79073.1 - 1.3e-07 30.8 1.1 2.7e-07 29.7 0.8 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EME79073.1 - 0.00033 19.6 0.1 0.00057 18.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EME79073.1 - 0.0011 17.9 0.7 0.0027 16.7 0.1 1.8 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Pterin_bind PF00809.17 EME79075.1 - 4.4e-64 215.7 0.1 9.6e-64 214.6 0.0 1.6 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EME79075.1 - 2.3e-42 143.7 0.0 4.9e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glyoxalase_2 PF12681.2 EME79076.1 - 3e-10 40.6 0.0 3.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME79076.1 - 4.6e-08 33.1 0.0 8.2e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EME79076.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RRN3 PF05327.6 EME79077.1 - 2.4e-137 458.4 0.6 4.3e-137 457.6 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 ATPgrasp_Ter PF15632.1 EME79077.1 - 0.031 13.0 0.0 0.32 9.6 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Mating_C PF12737.2 EME79077.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 RXT2_N PF08595.6 EME79077.1 - 2.3 7.9 8.8 11 5.8 1.3 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4336 PF14234.1 EME79078.1 - 6.7e-15 55.0 0.1 5.2e-11 42.2 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) FAD_binding_3 PF01494.14 EME79079.1 - 1.7e-23 83.2 0.0 1.6e-11 43.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EME79079.1 - 3.9e-07 29.3 0.0 0.00033 19.6 0.0 2.8 2 1 0 2 2 2 2 Lycopene cyclase protein SE PF08491.5 EME79079.1 - 0.0042 15.9 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase K_oxygenase PF13434.1 EME79079.1 - 0.0056 15.6 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EME79079.1 - 0.0059 15.5 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME79079.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME79079.1 - 0.0082 16.2 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME79079.1 - 0.011 15.7 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME79079.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA PF00004.24 EME79082.1 - 2.1e-36 125.0 0.0 3.4e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME79082.1 - 2e-06 27.0 0.0 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME79082.1 - 3.6e-06 27.8 0.1 2.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME79082.1 - 1.7e-05 24.7 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME79082.1 - 2.9e-05 24.2 0.1 0.00049 20.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME79082.1 - 3.2e-05 23.4 0.1 0.029 13.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EME79082.1 - 5.5e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EME79082.1 - 7e-05 22.8 1.9 0.00071 19.6 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EME79082.1 - 7.8e-05 22.5 0.0 0.00014 21.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME79082.1 - 0.00012 21.7 0.3 0.00087 19.0 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EME79082.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EME79082.1 - 0.00084 19.4 0.0 0.0031 17.6 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EME79082.1 - 0.00088 18.4 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EME79082.1 - 0.0015 18.7 0.2 0.0069 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME79082.1 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME79082.1 - 0.0029 16.7 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EME79082.1 - 0.0031 17.5 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.7 EME79082.1 - 0.0043 16.7 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 1 1 NACHT domain AAA_24 PF13479.1 EME79082.1 - 0.0054 16.3 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EME79082.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 EME79082.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EME79082.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SKI PF01202.17 EME79082.1 - 0.05 13.4 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase DUF815 PF05673.8 EME79082.1 - 0.06 12.2 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.7 EME79082.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.12 EME79082.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EME79082.1 - 0.066 11.8 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EME79082.1 - 0.074 12.7 0.0 0.2 11.3 0.0 1.6 1 1 1 2 2 1 0 Archaeal ATPase TIP49 PF06068.8 EME79082.1 - 0.085 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Guanylate_kin PF00625.16 EME79082.1 - 0.098 12.0 0.0 1.5 8.1 0.0 2.6 3 0 0 3 3 3 0 Guanylate kinase Viral_helicase1 PF01443.13 EME79082.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EME79082.1 - 0.12 11.5 0.0 0.51 9.4 0.0 1.9 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 EME79082.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EME79082.1 - 0.16 10.9 0.1 0.67 8.8 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 EME79082.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Nucleoplasmin PF03066.10 EME79082.1 - 3.2 7.2 6.0 6.4 6.2 4.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Thymidylat_synt PF00303.14 EME79083.1 - 1.7e-112 374.8 0.0 2e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Acyl_transf_1 PF00698.16 EME79084.1 - 1.4e-67 228.2 0.0 2.5e-67 227.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EME79084.1 - 4.3e-61 206.6 1.8 5.2e-61 206.3 0.5 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EME79084.1 - 1.6e-58 198.1 0.3 1.6e-58 198.1 0.2 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EME79084.1 - 5.8e-57 192.2 1.7 5.8e-57 192.2 1.2 2.3 3 0 0 3 3 2 1 KR domain adh_short PF00106.20 EME79084.1 - 1.5e-44 151.8 3.2 2.1e-44 151.3 1.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EME79084.1 - 3.3e-36 123.7 0.1 1.1e-35 122.0 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EME79084.1 - 2.2e-19 69.2 0.5 8.7e-19 67.3 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EME79084.1 - 1.4e-15 57.5 0.0 1.3e-14 54.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME79084.1 - 3.1e-13 49.7 0.0 7.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EME79084.1 - 1.8e-10 41.7 0.0 4.1e-09 37.4 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EME79084.1 - 2e-10 40.4 0.0 4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME79084.1 - 4.7e-08 33.4 0.0 1.9e-07 31.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME79084.1 - 5.5e-06 26.9 0.0 2.9e-05 24.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EME79084.1 - 0.00012 22.2 0.0 0.00041 20.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EME79084.1 - 0.00026 20.6 0.3 0.00074 19.2 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EME79084.1 - 0.0011 17.9 0.2 0.0024 16.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EME79084.1 - 0.0089 15.1 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EME79084.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 EME79084.1 - 0.29 10.6 0.0 1.3 8.5 0.0 2.1 3 0 0 3 3 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FA_hydroxylase PF04116.8 EME79085.1 - 5.1e-13 49.4 10.6 5.1e-13 49.4 7.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 EME79086.1 - 1.9e-06 27.8 0.0 4.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Aminotran_1_2 PF00155.16 EME79087.1 - 3.1e-31 108.6 0.0 4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EME79087.1 - 0.00024 19.5 0.0 0.00034 18.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EME79087.1 - 0.0055 15.8 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EME79087.1 - 0.0083 14.7 0.0 0.47 8.9 0.0 2.1 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 EME79087.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family RRM_5 PF13893.1 EME79087.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EME79088.1 - 1.2e-29 103.1 51.0 4.8e-28 97.8 35.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME79088.1 - 1.4e-14 53.2 30.3 5.7e-13 47.9 21.0 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.3 EME79088.1 - 0.0036 17.1 0.9 0.0036 17.1 0.6 2.9 2 2 0 2 2 2 1 Protein of unknown function (DUF3522) YrhK PF14145.1 EME79088.1 - 0.022 14.4 4.5 0.094 12.3 3.1 2.2 1 1 0 1 1 1 0 YrhK-like protein OATP PF03137.15 EME79088.1 - 2.9 5.8 13.2 0.15 10.1 0.1 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HpcH_HpaI PF03328.9 EME79091.1 - 1.3e-39 135.4 0.0 2.8e-39 134.3 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EME79091.1 - 7e-14 51.3 0.0 4.1e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.13 EME79091.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain 2-Hacid_dh_C PF02826.14 EME79092.1 - 1.8e-40 138.0 0.0 7e-27 93.7 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME79092.1 - 0.069 12.6 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gp_dh_N PF00044.19 EME79092.1 - 0.29 11.0 1.0 1.1 9.2 0.6 1.9 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PWWP PF00855.12 EME79093.1 - 5e-17 61.8 0.0 5e-17 61.8 0.0 2.8 2 1 0 2 2 2 1 PWWP domain Methyltransf_2 PF00891.13 EME79094.1 - 2.1e-32 112.2 0.0 3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_8 PF05148.10 EME79095.1 - 3.4e-61 206.6 0.0 3.7e-58 196.7 0.0 2.7 2 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EME79095.1 - 5.6e-07 29.9 0.0 2e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME79095.1 - 0.0064 16.1 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EME79095.1 - 0.0075 16.6 0.1 0.67 10.3 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME79095.1 - 0.026 14.2 0.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3306 PF11748.3 EME79095.1 - 0.077 13.6 0.4 0.077 13.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Glyco_hydro_2_N PF02837.13 EME79096.1 - 1.5e-27 96.1 0.0 2.8e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EME79096.1 - 2.4e-14 52.9 0.2 4.7e-14 51.9 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EME79096.1 - 1.8e-07 31.5 0.0 3.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EME79096.1 - 0.095 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain AA_permease PF00324.16 EME79098.1 - 4.9e-137 457.1 45.1 6e-137 456.8 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME79098.1 - 3.1e-30 105.0 50.9 3.8e-30 104.7 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease Vps53_N PF04100.7 EME79099.1 - 2.1e-108 362.5 1.3 2.1e-108 362.5 0.9 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 EME79099.1 - 1e-09 37.7 2.9 2.4e-09 36.4 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EME79099.1 - 0.0013 17.4 1.9 0.002 16.8 1.0 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF2451 PF10474.4 EME79099.1 - 0.024 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.6 EME79099.1 - 0.17 11.7 5.4 0.11 12.3 0.8 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TAP_C PF03943.8 EME79100.1 - 9.8e-10 37.7 0.2 1.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EME79100.1 - 2.6e-05 23.7 12.3 0.00027 20.4 1.6 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EME79100.1 - 0.015 15.6 0.1 0.063 13.6 0.0 2.0 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 EME79100.1 - 0.061 13.4 6.0 0.36 11.0 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_9 PF14580.1 EME79100.1 - 0.13 11.7 0.2 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 EME79100.1 - 0.37 11.1 9.7 1.5 9.3 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EME79100.1 - 1.1 9.5 6.6 7.6 7.0 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 EME79100.1 - 3.3 7.5 9.5 2.8 7.7 4.4 2.5 2 1 0 2 2 2 0 Leucine rich repeat ERO1 PF04137.10 EME79101.1 - 7.8e-132 439.6 0.0 9.6e-132 439.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CKS PF01111.14 EME79103.1 - 4.5e-36 122.5 1.0 6e-36 122.1 0.3 1.5 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit DUF2235 PF09994.4 EME79104.1 - 9.7e-42 143.2 0.0 1.8e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 EME79104.1 - 6.6e-10 39.5 0.2 1.8e-09 38.1 0.1 1.9 2 0 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME79104.1 - 3.6e-08 33.3 0.1 8.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EME79104.1 - 4.7e-06 25.8 0.6 0.0061 15.6 0.0 2.2 2 0 0 2 2 2 2 Septin Ras PF00071.17 EME79104.1 - 1e-05 25.0 1.1 4.2e-05 22.9 0.7 1.9 1 1 0 1 1 1 1 Ras family DUF258 PF03193.11 EME79104.1 - 0.0011 18.2 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EME79104.1 - 0.0072 16.0 0.1 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EME79104.1 - 0.062 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EME79104.1 - 0.062 14.1 1.1 0.32 11.8 0.7 2.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME79104.1 - 0.073 13.2 0.3 0.52 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EME79104.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 EME79104.1 - 0.17 11.1 0.0 0.84 8.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 EME79104.1 - 3.7 7.8 5.2 11 6.2 3.6 1.7 1 1 0 1 1 1 0 AAA domain Pro_isomerase PF00160.16 EME79105.1 - 2e-56 190.4 0.3 2.5e-56 190.2 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD P34-Arc PF04045.9 EME79107.1 - 7.3e-105 349.5 0.3 9.5e-105 349.2 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EME79107.1 - 0.005 16.2 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TGT_C2 PF14810.1 EME79108.1 - 0.041 13.7 0.1 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Zn_clus PF00172.13 EME79109.1 - 0.022 14.6 10.3 0.022 14.6 7.2 2.1 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rax2 PF12768.2 EME79110.1 - 2.3e-86 289.4 17.2 4.5e-79 265.5 0.1 5.1 5 0 0 5 5 5 4 Cortical protein marker for cell polarity SKG6 PF08693.5 EME79110.1 - 0.0069 15.6 3.4 0.017 14.3 2.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CPSase_L_D2 PF02786.12 EME79112.1 - 2.1e-105 350.6 0.0 1.3e-82 276.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EME79112.1 - 2.4e-42 143.5 0.1 7.5e-42 141.9 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EME79112.1 - 9.5e-36 123.2 0.1 1.4e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EME79112.1 - 2.5e-33 114.4 0.0 9.7e-16 57.8 0.0 3.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EME79112.1 - 5.4e-22 77.9 0.0 5.5e-07 28.6 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EME79112.1 - 5.6e-19 68.1 0.0 9.9e-09 34.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME79112.1 - 1.1e-15 57.6 0.2 7.8e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EME79112.1 - 3.4e-08 33.1 0.0 0.00014 21.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EME79112.1 - 5.9e-07 29.2 0.0 0.043 13.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EME79112.1 - 2.1e-06 27.7 0.1 0.035 13.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 EME79112.1 - 0.002 17.4 0.0 0.32 10.1 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain TBP PF00352.16 EME79112.1 - 0.13 11.5 0.1 92 2.5 0.0 4.0 4 1 1 5 5 5 0 Transcription factor TFIID (or TATA-binding protein, TBP) Adaptin_N PF01602.15 EME79113.1 - 3.6e-132 441.3 12.3 4.3e-132 441.1 8.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EME79113.1 - 1.1e-15 57.9 4.3 1.7e-15 57.2 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EME79113.1 - 6e-15 55.3 6.5 2.3e-09 37.3 0.2 4.4 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EME79113.1 - 2.6e-10 39.4 4.0 0.01 15.8 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EME79113.1 - 8.1e-05 22.9 6.6 0.025 15.0 0.1 5.5 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 EME79113.1 - 0.0003 20.2 1.2 0.62 9.3 0.1 3.4 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 EME79113.1 - 0.00034 20.3 1.2 14 5.6 0.0 5.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EME79113.1 - 0.036 13.8 0.0 1.1 9.0 0.0 3.1 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF1077 PF06417.7 EME79114.1 - 4.9e-50 168.0 0.1 6.3e-50 167.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Thioredoxin PF00085.15 EME79115.1 - 2.3e-47 158.9 0.0 5.2e-26 90.3 0.0 4.5 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 EME79115.1 - 7.9e-18 64.9 0.0 5.1e-06 26.4 0.0 4.3 2 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EME79115.1 - 2.9e-11 43.5 4.0 0.0021 18.2 0.1 4.2 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME79115.1 - 1.4e-08 34.7 0.6 0.028 14.5 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EME79115.1 - 1e-06 28.6 0.4 0.00015 21.6 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EME79115.1 - 3.5e-05 23.5 0.0 0.25 11.1 0.0 4.0 4 0 0 4 4 4 1 Thioredoxin domain HyaE PF07449.6 EME79115.1 - 0.0024 17.7 0.0 0.96 9.3 0.0 2.7 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 EME79115.1 - 0.034 13.8 0.3 1.1 8.8 0.0 3.0 4 0 0 4 4 4 0 AhpC/TSA family Thioredoxin_4 PF13462.1 EME79115.1 - 0.13 12.2 7.8 0.16 11.9 0.8 3.3 4 0 0 4 4 4 0 Thioredoxin ETC_C1_NDUFA5 PF04716.9 EME79116.1 - 6.2e-19 67.2 2.2 7.4e-19 67.0 0.3 2.0 2 0 0 2 2 2 1 ETC complex I subunit conserved region Fungal_trans PF04082.13 EME79118.1 - 2.3e-12 46.3 0.0 3.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79118.1 - 6.9e-08 32.2 12.1 1.2e-07 31.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME79120.1 - 5.7e-36 123.9 26.9 7.5e-36 123.5 18.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EME79121.1 - 7.8e-14 51.1 0.6 1.4e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79121.1 - 4e-07 29.8 6.5 7.8e-07 28.8 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 EME79122.1 - 6e-08 32.5 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 RCR PF12273.3 EME79123.1 - 5.2e-08 33.5 9.5 3.8e-07 30.7 6.6 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WWbp PF10349.4 EME79123.1 - 3.7 8.4 13.7 7.1 7.5 9.5 1.5 1 1 0 1 1 1 0 WW-domain ligand protein DUF3752 PF12572.3 EME79124.1 - 3.8e-34 118.0 8.1 3.8e-34 118.0 5.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Vps8 PF12816.2 EME79125.1 - 1.5e-66 223.3 0.1 5.7e-66 221.5 0.0 2.0 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EME79125.1 - 2.9e-10 39.9 0.3 0.00015 21.3 0.0 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EME79125.1 - 2.8e-05 23.8 0.3 9.3e-05 22.1 0.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME79125.1 - 0.0012 18.8 0.4 0.0034 17.3 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME79125.1 - 0.003 17.2 0.2 0.0082 15.8 0.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME79125.1 - 0.0068 16.4 0.1 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger WD40 PF00400.27 EME79125.1 - 0.021 14.7 0.2 0.083 12.8 0.1 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat KR PF08659.5 EME79125.1 - 0.027 14.1 0.5 1.7 8.2 0.1 2.5 2 0 0 2 2 2 0 KR domain zf-C3HC4 PF00097.20 EME79125.1 - 0.027 14.1 0.1 0.086 12.5 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EME79125.1 - 0.028 14.1 0.3 0.028 14.1 0.2 2.0 2 0 0 2 2 2 0 PHD-finger NUDIX PF00293.23 EME79128.1 - 2.2e-11 43.5 0.0 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain UQ_con PF00179.21 EME79129.1 - 4.3e-26 91.0 0.1 5e-26 90.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME79129.1 - 6e-06 26.0 0.0 8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME79129.1 - 0.0011 18.8 0.7 0.0025 17.7 0.5 1.8 1 1 1 2 2 2 1 RWD domain Pkinase PF00069.20 EME79130.1 - 3.3e-71 239.4 0.0 4.2e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79130.1 - 9.9e-36 123.1 0.0 1.3e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME79130.1 - 0.00015 20.8 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EME79130.1 - 0.0076 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EME79130.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tmemb_14 PF03647.8 EME79131.1 - 7.9e-22 77.4 10.3 9.2e-22 77.2 7.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C GBP_PSP PF02425.10 EME79131.1 - 3.2 7.3 6.1 1.2 8.7 1.3 2.1 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide DAD PF02109.11 EME79132.1 - 1.2e-49 167.1 2.3 1.4e-49 166.8 1.6 1.0 1 0 0 1 1 1 1 DAD family DUF3341 PF11821.3 EME79132.1 - 0.051 13.0 0.2 5 6.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Pyrophosphatase PF00719.14 EME79133.1 - 8.8e-54 181.1 0.2 1.2e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF4551 PF15087.1 EME79134.1 - 0.2 10.0 5.8 0.34 9.2 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RRM_1 PF00076.17 EME79135.1 - 1.3e-21 75.9 0.0 1.7e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME79135.1 - 6.1e-16 58.1 0.0 7.8e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME79135.1 - 1.5e-10 40.7 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RTC PF01137.16 EME79136.1 - 2.1e-33 115.0 0.1 2.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EME79136.1 - 6.9e-29 99.9 0.1 1.3e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CTDII PF01556.13 EME79137.1 - 2.3e-26 91.4 2.0 4.6e-21 74.5 0.3 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EME79137.1 - 1.4e-22 79.1 2.1 2.6e-22 78.3 1.5 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EME79137.1 - 2.5e-10 40.2 21.2 5.1e-10 39.2 14.7 1.5 1 0 0 1 1 1 1 DnaJ central domain BRO1 PF03097.13 EME79138.1 - 7.3e-134 446.2 3.7 7.3e-134 446.2 2.6 2.4 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EME79138.1 - 1.1e-94 316.8 18.5 2.9e-94 315.3 12.8 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Syntaxin-6_N PF09177.6 EME79138.1 - 0.058 13.8 14.1 0.57 10.6 0.6 4.8 4 1 0 4 4 4 0 Syntaxin 6, N-terminal DUF4239 PF14023.1 EME79138.1 - 0.8 9.0 8.0 0.12 11.7 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) E1-E2_ATPase PF00122.15 EME79140.1 - 5.9e-70 234.8 6.7 1.3e-69 233.8 0.2 3.4 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 EME79140.1 - 1.5e-22 81.0 0.0 1.6e-21 77.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME79140.1 - 1.6e-12 47.9 0.0 3.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME79140.1 - 2.3e-10 39.7 0.0 5e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EME79140.1 - 0.0013 18.4 0.2 0.0037 16.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME79140.1 - 0.0017 18.2 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit adh_short PF00106.20 EME79141.1 - 3.1e-28 98.7 0.6 5.7e-28 97.9 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME79141.1 - 4.4e-20 72.4 0.1 5.5e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME79141.1 - 2.7e-13 49.9 0.7 7.5e-13 48.5 0.5 1.8 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME79141.1 - 0.00091 18.9 0.5 0.0025 17.5 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EME79141.1 - 0.0042 16.5 0.9 0.0049 16.3 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME79141.1 - 0.02 13.7 0.3 0.033 13.0 0.1 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PHD PF00628.24 EME79144.1 - 4.7e-09 35.8 8.8 1.1e-08 34.6 6.1 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EME79144.1 - 2.6e-05 24.5 0.0 2.6e-05 24.5 0.0 3.7 3 1 0 3 3 3 1 SET domain Chitin_synth_1 PF01644.12 EME79145.1 - 3.7e-83 277.2 0.0 5.4e-83 276.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EME79145.1 - 9.8e-33 111.6 0.2 1.9e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EME79145.1 - 6.5e-23 80.9 0.2 1e-21 76.9 0.0 2.2 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EME79145.1 - 2.1e-08 34.1 0.4 2.1e-08 34.1 0.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EME79145.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF3278 PF11683.3 EME79145.1 - 0.051 13.5 4.4 0.11 12.4 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) DUF3989 PF13150.1 EME79145.1 - 1.7 8.1 6.2 6.9 6.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) HET PF06985.6 EME79146.1 - 2.2e-15 57.0 0.5 3.1e-15 56.5 0.3 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_17 PF00332.13 EME79147.1 - 0.0006 18.9 0.1 0.0059 15.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 FG-GAP PF01839.18 EME79147.1 - 0.094 12.4 0.7 0.23 11.1 0.5 1.7 1 0 0 1 1 1 0 FG-GAP repeat Med3 PF11593.3 EME79147.1 - 0.16 11.1 6.7 0.2 10.8 4.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2406 PF10295.4 EME79149.1 - 5.8e-19 68.3 0.8 1.9e-18 66.6 0.6 2.0 1 1 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 EME79150.1 - 1e-15 57.4 5.5 1.4e-15 56.9 3.8 1.2 1 0 0 1 1 1 1 VMA21-like domain Claudin_2 PF13903.1 EME79150.1 - 0.087 12.5 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SNF2_N PF00176.18 EME79151.1 - 5.1e-60 202.8 0.0 8.1e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME79151.1 - 1.8e-13 50.1 0.0 4.7e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CUE PF02845.11 EME79151.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.7 1 0 0 1 1 1 0 CUE domain UBA PF00627.26 EME79151.1 - 0.13 12.0 0.5 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Peptidase_M20 PF01546.23 EME79153.1 - 5.5e-28 97.7 0.1 1.1e-27 96.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME79153.1 - 2.4e-14 53.0 0.0 4.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EME79153.1 - 0.00056 19.6 0.0 0.00099 18.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PWI PF01480.12 EME79154.1 - 7.1e-23 80.5 0.1 1.1e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 PWI domain Glyco_hydro_43 PF04616.9 EME79156.1 - 1.1e-14 54.2 0.9 1.8e-14 53.5 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-C2H2_4 PF13894.1 EME79157.1 - 3.2e-10 39.6 12.8 0.0029 17.8 0.1 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger DUF629 PF04780.7 EME79157.1 - 0.009 14.5 1.2 0.017 13.7 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-Di19 PF05605.7 EME79157.1 - 0.017 15.2 8.5 0.84 9.8 0.0 3.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EME79157.1 - 0.021 15.1 11.4 0.94 9.9 0.0 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EME79157.1 - 0.038 14.0 5.0 0.12 12.5 0.1 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 EME79157.1 - 0.18 11.4 2.9 1.7 8.2 0.0 3.0 3 0 0 3 3 3 0 GAGA factor zf-C2H2_jaz PF12171.3 EME79157.1 - 1.1 9.4 5.4 59 3.9 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EME79157.1 - 3.3 7.7 7.6 26 4.9 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME79157.1 - 7.7 7.0 8.7 69 4.0 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger double domain EMI PF07546.8 EME79158.1 - 0.11 12.9 1.1 0.16 12.4 0.7 1.3 1 0 0 1 1 1 0 EMI domain Zip PF02535.17 EME79159.1 - 2.4e-49 168.0 0.0 3.4e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Asp PF00026.18 EME79160.1 - 3.8e-06 26.3 0.8 1.1e-05 24.8 0.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 EME79160.1 - 0.0075 14.9 0.1 0.01 14.4 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4328 PF14219.1 EME79160.1 - 0.014 14.6 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) EphA2_TM PF14575.1 EME79160.1 - 0.044 14.1 0.1 0.079 13.3 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.6 EME79160.1 - 0.046 13.4 0.5 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 DAP10 membrane protein FixQ PF05545.6 EME79160.1 - 0.047 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Rifin_STEVOR PF02009.11 EME79160.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Aa_trans PF01490.13 EME79162.1 - 1.6e-33 115.8 31.4 1.8e-33 115.6 21.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Diphtheria_T PF02764.9 EME79162.1 - 0.2 11.4 1.1 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Diphtheria toxin, T domain DUF3602 PF12223.3 EME79163.1 - 1.1e-09 38.5 16.3 7.4e-05 23.0 1.2 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Dehydrin PF00257.14 EME79163.1 - 0.03 14.6 8.4 0.032 14.5 5.8 1.2 1 0 0 1 1 1 0 Dehydrin Mito_carr PF00153.22 EME79164.1 - 4.7e-47 157.6 7.3 6.4e-18 64.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 EME79165.1 - 2e-08 33.8 0.0 0.0057 16.4 0.0 3.0 1 1 1 2 2 2 2 CBS domain F-box-like PF12937.2 EME79166.1 - 1.7e-08 34.0 0.1 4.6e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME79166.1 - 4.3e-08 32.6 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Pilt PF15453.1 EME79169.1 - 0.2 11.3 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Peptidase_A4 PF01828.12 EME79171.1 - 1.6e-48 164.5 0.4 1.9e-48 164.2 0.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1746 PF08508.5 EME79171.1 - 1.9e-21 76.1 0.1 3.6e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF916 PF06030.7 EME79171.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) AAA PF00004.24 EME79172.1 - 7.2e-15 55.3 0.0 2.4e-14 53.6 0.0 1.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EME79172.1 - 1.8e-12 47.2 0.0 3.7e-07 29.9 0.0 2.7 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EME79172.1 - 2.7e-10 40.0 0.0 6.4e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EME79172.1 - 2.4e-09 36.4 0.0 7.3e-08 31.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EME79172.1 - 5.7e-07 29.7 0.0 4.6e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME79172.1 - 4.1e-06 26.0 0.0 1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EME79172.1 - 1e-05 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME79172.1 - 1.2e-05 25.3 0.5 0.00048 20.1 0.0 3.2 2 2 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 EME79172.1 - 2.1e-05 24.1 0.0 7e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EME79172.1 - 0.0005 19.3 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EME79172.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EME79172.1 - 0.00057 19.5 1.6 0.0067 16.0 1.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME79172.1 - 0.0022 18.7 0.0 0.006 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME79172.1 - 0.0027 17.4 0.1 0.026 14.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EME79172.1 - 0.0037 16.2 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EME79172.1 - 0.0042 16.0 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EME79172.1 - 0.011 15.2 0.0 0.033 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EME79172.1 - 0.019 14.5 0.3 0.13 11.8 0.0 2.5 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EME79172.1 - 0.027 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EME79172.1 - 0.035 13.5 0.0 0.3 10.4 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EME79172.1 - 0.038 13.4 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EME79172.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME79172.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 EME79172.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SNF2_N PF00176.18 EME79172.1 - 0.086 11.6 0.0 2.6 6.7 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_3 PF07726.6 EME79172.1 - 0.09 12.3 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EME79172.1 - 0.096 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EME79172.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MutS_V PF00488.16 EME79173.1 - 5.5e-83 277.9 0.0 8.8e-83 277.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME79173.1 - 1.6e-35 122.7 8.8 3.1e-35 121.8 6.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EME79173.1 - 8.7e-21 74.0 0.0 2.3e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EME79173.1 - 2e-09 37.6 0.0 5.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EME79173.1 - 0.0024 18.0 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EME79173.1 - 0.0026 17.6 0.0 0.16 11.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EME79173.1 - 0.015 14.8 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EME79173.1 - 0.025 14.8 0.6 0.69 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SnoaL_3 PF13474.1 EME79173.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Myosin_head PF00063.16 EME79174.1 - 2e-234 779.7 6.0 3.1e-234 779.1 4.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EME79174.1 - 1.5e-45 155.0 0.0 2.6e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EME79174.1 - 4.9e-14 51.4 0.2 9.5e-14 50.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME79174.1 - 5.5e-13 48.2 0.1 1.2e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EME79174.1 - 5.3e-10 38.6 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EME79174.1 - 0.0029 17.7 0.0 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 EME79174.1 - 0.01 15.4 8.5 0.54 10.0 1.0 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif Zeta_toxin PF06414.7 EME79174.1 - 0.022 13.8 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EME79174.1 - 0.039 13.2 0.4 4.1 6.6 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.1 EME79174.1 - 0.04 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain SH3_3 PF08239.6 EME79174.1 - 0.059 13.5 0.2 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain AAA_17 PF13207.1 EME79174.1 - 0.065 14.0 0.0 0.2 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EME79174.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain YjeF_N PF03853.10 EME79175.1 - 1.1e-36 125.9 0.0 1.3e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 EME79177.1 - 4.7e-37 126.8 0.0 6e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME79177.1 - 7.5e-14 51.3 0.0 7.6e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IMPDH PF00478.20 EME79177.1 - 0.035 13.0 0.0 0.073 11.9 0.0 1.5 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain AAA_33 PF13671.1 EME79178.1 - 4.4e-16 59.0 0.0 4.9e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME79178.1 - 1.1e-09 37.6 0.0 1.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EME79178.1 - 2.5e-08 34.2 0.2 3.1e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME79178.1 - 2.6e-05 25.0 0.1 3.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME79178.1 - 0.00021 20.5 0.0 0.00025 20.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 dNK PF01712.14 EME79178.1 - 0.036 13.9 0.8 0.13 12.1 0.4 1.9 1 1 1 2 2 2 0 Deoxynucleoside kinase SKI PF01202.17 EME79178.1 - 0.049 13.5 0.5 0.36 10.6 0.4 2.1 1 1 0 1 1 1 0 Shikimate kinase Glyco_hydro_31 PF01055.21 EME79180.1 - 1.4e-54 185.6 8.6 3.2e-43 148.1 1.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 GalP_UDP_transf PF01087.17 EME79182.1 - 2.7e-69 232.9 0.5 3.9e-68 229.1 0.3 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EME79182.1 - 7.7e-58 194.7 0.1 1.6e-57 193.7 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain AA_permease_2 PF13520.1 EME79183.1 - 1.2e-49 169.0 55.8 1.4e-49 168.7 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME79183.1 - 1.1e-24 86.6 50.7 1.4e-24 86.2 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4112 PF13430.1 EME79183.1 - 6 6.8 8.9 6.2 6.7 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4112) Herpes_US9 PF06072.6 EME79183.1 - 7 6.5 0.0 7 6.5 0.0 4.1 5 1 0 5 5 5 0 Alphaherpesvirus tegument protein US9 YlaH PF14036.1 EME79183.1 - 8.8 6.4 13.8 0.14 12.2 1.2 3.8 3 1 1 4 4 4 0 YlaH-like protein DUF4491 PF14898.1 EME79184.1 - 0.22 11.6 0.2 0.22 11.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4491) PhyH PF05721.8 EME79186.1 - 7.5e-20 71.8 0.0 1.6e-19 70.8 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EME79186.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Phosphodiest PF01663.17 EME79187.1 - 3.1e-22 79.4 0.0 6e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase HD PF01966.17 EME79187.1 - 2.7e-07 30.6 0.0 5.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_4 PF13328.1 EME79187.1 - 0.0045 16.7 0.2 0.0099 15.5 0.0 1.7 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 EME79187.1 - 0.045 13.0 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 HDOD domain Fungal_trans PF04082.13 EME79188.1 - 3.1e-12 45.9 0.2 5.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79188.1 - 6.2e-09 35.6 9.7 1e-08 34.9 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2417 PF10329.4 EME79189.1 - 7.3e-86 287.3 0.0 1e-85 286.8 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EME79189.1 - 8.5e-07 29.0 0.4 2.2e-06 27.7 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME79190.1 - 2.1e-22 80.1 2.5 3.6e-22 79.3 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME79190.1 - 3.5e-11 43.0 0.4 8e-11 41.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME79190.1 - 3.3e-05 23.5 0.2 0.01 15.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME79190.1 - 0.00013 21.2 0.0 0.0026 17.0 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EME79190.1 - 0.00034 20.9 0.8 0.00091 19.5 0.3 1.8 2 1 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.3 EME79190.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EME79190.1 - 0.048 13.2 0.2 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.23 EME79191.1 - 1.1e-96 324.7 0.0 1.4e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME79191.1 - 3.2e-05 23.6 0.0 5.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydantoinase_B PF02538.9 EME79191.1 - 0.27 9.4 1.2 0.5 8.5 0.9 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase FAD_binding_3 PF01494.14 EME79193.1 - 3.6e-08 32.8 0.5 0.00055 19.0 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.19 EME79193.1 - 0.0028 16.5 0.1 0.0048 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME79193.1 - 0.0049 16.8 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME79193.1 - 0.0084 16.4 0.2 0.017 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME79193.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3893 PF13032.1 EME79193.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) Pyr_redox_2 PF07992.9 EME79193.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME79193.1 - 0.056 12.5 0.1 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family MRP_L53 PF10780.4 EME79195.1 - 5.1e-10 39.1 0.1 8.5e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RTC4 PF14474.1 EME79196.1 - 5.5e-24 84.4 0.4 1.3e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 RTC4-like domain TraI_2 PF07514.6 EME79196.1 - 0.021 13.5 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative helicase CBFD_NFYB_HMF PF00808.18 EME79197.1 - 2.1e-29 101.3 1.4 2.7e-29 101.0 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME79197.1 - 6.7e-08 32.5 0.3 1.5e-07 31.4 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EME79197.1 - 0.00025 20.7 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EME79197.1 - 0.00044 19.9 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EME79197.1 - 0.011 16.0 0.1 0.028 14.6 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A PAN_3 PF08277.7 EME79197.1 - 0.069 12.7 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain PAN_2 PF08276.6 EME79197.1 - 0.13 12.1 1.0 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 PAN-like domain Prefoldin_2 PF01920.15 EME79198.1 - 9.2e-27 92.8 6.2 1.2e-26 92.5 4.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.4 EME79198.1 - 0.015 14.8 9.4 0.18 11.4 1.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) UBN2 PF14223.1 EME79198.1 - 0.019 14.7 0.9 1.6 8.5 0.0 2.4 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type CENP-F_leu_zip PF10473.4 EME79198.1 - 0.051 13.4 5.4 0.15 11.9 0.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 EME79198.1 - 0.13 11.9 5.4 0.97 9.0 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit Tho2 PF11262.3 EME79198.1 - 0.15 11.1 1.2 0.88 8.5 0.7 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 p25-alpha PF05517.7 EME79198.1 - 0.19 12.0 2.0 0.77 10.0 0.1 2.0 2 0 0 2 2 2 0 p25-alpha GAS PF13851.1 EME79198.1 - 0.28 10.3 8.3 1 8.5 5.7 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Dad3 PF08656.5 EME79198.1 - 0.63 9.7 3.3 0.89 9.3 0.4 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 IncA PF04156.9 EME79198.1 - 1.3 8.6 6.0 2.3 7.7 4.1 1.5 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.6 EME79198.1 - 1.6 8.4 6.1 2.6 7.7 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cmc1 PF08583.5 EME79200.1 - 9.7e-16 57.3 6.4 1.1e-15 57.1 4.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MatP PF06303.7 EME79200.1 - 0.036 13.9 0.5 0.036 13.9 0.3 1.1 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome DUF3128 PF11326.3 EME79200.1 - 0.067 13.3 1.8 0.082 13.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Amidase PF01425.16 EME79202.1 - 7.8e-70 235.9 0.0 9.8e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Amidase tRNA-synt_2c PF01411.14 EME79204.1 - 9.7e-215 714.0 0.1 1.5e-214 713.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EME79204.1 - 6e-17 61.2 0.2 1.4e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EME79204.1 - 1.7e-06 27.5 3.4 4.8e-06 26.1 2.4 1.8 1 0 0 1 1 1 1 DHHA1 domain Pkinase PF00069.20 EME79206.1 - 1.3e-58 198.2 0.2 1.5e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79206.1 - 3.1e-19 69.0 0.0 4.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME79206.1 - 3.7e-07 30.1 0.1 2.7e-05 24.0 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME79206.1 - 0.0067 16.0 0.1 0.019 14.5 0.1 1.9 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EME79206.1 - 0.0097 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Transgly PF00912.17 EME79206.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase Kdo PF06293.9 EME79206.1 - 0.057 12.4 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-DHHC PF01529.15 EME79207.1 - 1.8e-32 112.1 7.5 2.9e-32 111.4 5.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase WD40 PF00400.27 EME79209.1 - 2.4e-22 77.9 3.0 7e-05 22.5 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EME79210.1 - 5.9e-30 104.1 10.4 5.9e-30 104.1 7.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 Glyco_hydro_71 PF03659.9 EME79211.1 - 2.4e-77 260.0 16.8 3e-77 259.7 11.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EME79211.1 - 0.012 15.3 3.3 0.049 13.3 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) PepSY_2 PF13670.1 EME79212.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Orthoreo_P10 PF07204.6 EME79212.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Aldolase_II PF00596.16 EME79213.1 - 5e-47 159.8 0.0 6.1e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Mago_nashi PF02792.9 EME79214.1 - 0.17 11.5 1.3 5.4 6.7 0.3 2.0 1 1 1 2 2 2 0 Mago nashi protein R3H-assoc PF13902.1 EME79215.1 - 8.4e-22 77.5 5.8 8.4e-22 77.5 4.0 2.1 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 EME79215.1 - 2.3e-05 23.9 0.0 0.00066 19.3 0.0 2.7 2 0 0 2 2 2 1 R3H domain Cauli_DNA-bind PF03310.8 EME79215.1 - 0.14 11.9 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Methyltransf_23 PF13489.1 EME79218.1 - 3e-08 33.5 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME79218.1 - 0.00082 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME79218.1 - 0.0018 18.7 0.0 0.006 17.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME79218.1 - 0.075 13.6 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nucleoporin_C PF03177.9 EME79219.1 - 7.4e-112 374.7 2.8 9.8e-112 374.3 1.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EME79219.1 - 1.6e-64 218.2 0.0 2.2e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 EME79221.1 - 3.5e-23 82.0 6.0 4e-23 81.8 4.1 1.0 1 0 0 1 1 1 1 Yqey-like protein DUF892 PF05974.7 EME79221.1 - 0.028 14.2 1.3 0.044 13.5 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) CM_2 PF01817.16 EME79221.1 - 0.049 13.7 0.8 0.092 12.8 0.5 1.5 1 0 0 1 1 1 0 Chorismate mutase type II BDV_P24 PF06595.6 EME79221.1 - 0.26 11.0 2.2 0.19 11.4 0.4 1.8 2 1 0 2 2 2 0 Borna disease virus P24 protein DUF2781 PF10914.3 EME79222.1 - 1.6e-37 128.6 13.8 1.8e-37 128.3 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) p450 PF00067.17 EME79223.1 - 2.1e-33 115.5 0.0 2.7e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trehalose_PPase PF02358.11 EME79223.1 - 0.04 12.8 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase Barwin PF00967.12 EME79224.1 - 3.3e-05 23.5 0.3 3.7e-05 23.3 0.2 1.0 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EME79224.1 - 0.00061 19.7 0.0 0.00065 19.6 0.0 1.1 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EME79224.1 - 0.0067 16.4 0.2 0.011 15.7 0.1 1.3 1 1 0 1 1 1 1 Cerato-platanin Dicty_CAR PF05462.6 EME79226.1 - 5.5e-06 25.4 7.1 6.6e-05 21.9 0.5 2.2 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EME79226.1 - 9.6e-05 21.5 5.5 9.6e-05 21.5 3.8 2.1 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) Haemocyan_bet_s PF14830.1 EME79226.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Haemocyanin beta-sandwich DUF202 PF02656.10 EME79230.1 - 5.8e-18 64.8 0.0 8.7e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Cation_efflux PF01545.16 EME79231.1 - 2e-79 266.6 2.9 9.6e-79 264.4 2.0 1.8 1 1 0 1 1 1 1 Cation efflux family NicO PF03824.11 EME79231.1 - 0.0019 17.5 0.2 0.0019 17.5 0.1 1.9 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF566 PF04484.7 EME79231.1 - 0.66 9.4 7.3 0.9 8.9 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) ABC2_membrane_5 PF13346.1 EME79231.1 - 4.9 6.3 10.1 0.3 10.3 1.7 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_16 PF00722.16 EME79233.1 - 4.4e-07 29.3 0.4 3e-06 26.6 0.0 2.4 2 1 1 4 4 4 1 Glycosyl hydrolases family 16 Epimerase PF01370.16 EME79234.1 - 1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME79234.1 - 4.1e-07 29.1 0.1 1.3e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME79234.1 - 4.3e-07 30.1 0.0 5.9e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EME79234.1 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EME79234.1 - 0.00067 18.4 0.0 0.0066 15.1 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME79234.1 - 0.016 14.1 0.0 0.042 12.7 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Saccharop_dh PF03435.13 EME79234.1 - 0.049 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 EME79234.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.18 EME79234.1 - 0.08 12.7 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain BAH PF01426.13 EME79236.1 - 4e-09 36.2 0.0 8.8e-09 35.1 0.0 1.6 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H_2 PF13832.1 EME79236.1 - 0.0054 16.7 0.3 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME79236.1 - 0.0087 16.1 0.8 0.017 15.2 0.2 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.24 EME79236.1 - 0.0098 15.5 2.4 0.011 15.3 0.3 2.1 2 0 0 2 2 2 1 PHD-finger DUF2405 PF10293.4 EME79236.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) zf-RING-like PF08746.6 EME79236.1 - 0.093 12.7 1.4 0.19 11.7 0.3 1.9 2 0 0 2 2 2 0 RING-like domain PH PF00169.24 EME79237.1 - 4e-05 23.7 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EME79237.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain WD40 PF00400.27 EME79238.1 - 1.9e-70 230.4 19.0 2.5e-09 36.6 0.0 10.8 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EME79238.1 - 1e-11 44.6 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EME79238.1 - 4.4e-09 35.5 0.1 0.17 10.5 0.0 5.4 4 2 1 6 6 6 5 Nup133 N terminal like Nup160 PF11715.3 EME79238.1 - 2.1e-08 32.7 6.4 0.079 11.0 0.0 5.9 3 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF4259 PF14078.1 EME79241.1 - 0.08 13.4 1.6 0.14 12.6 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) Zn_Tnp_IS91 PF14319.1 EME79241.1 - 0.15 11.6 1.3 0.25 10.8 0.9 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-MYND PF01753.13 EME79241.1 - 1.4 8.8 6.2 2.7 7.9 4.3 1.4 1 0 0 1 1 1 0 MYND finger LysM PF01476.15 EME79242.1 - 3.7e-31 106.7 0.2 2.4e-14 52.9 0.0 2.9 3 0 0 3 3 3 2 LysM domain GerE PF00196.14 EME79242.1 - 0.073 12.4 0.0 9.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Nop14 PF04147.7 EME79244.1 - 2e-225 750.5 33.4 2.2e-173 578.3 10.8 2.0 1 1 1 2 2 2 2 Nop14-like family REV PF00424.13 EME79245.1 - 0.15 11.9 2.3 0.25 11.2 0.4 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) 3-HAO PF06052.7 EME79246.1 - 3.3e-58 195.3 0.0 4.2e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EME79246.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DZR PF12773.2 EME79246.1 - 0.01 15.6 6.4 0.023 14.5 4.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EME79246.1 - 0.016 14.4 1.7 0.28 10.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cupin_1 PF00190.17 EME79246.1 - 0.018 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Cupin C1_1 PF00130.17 EME79246.1 - 0.23 11.2 4.2 2 8.2 0.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.1 EME79246.1 - 0.27 10.9 2.9 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal YgbA_NO PF11756.3 EME79246.1 - 0.29 11.1 1.9 0.48 10.4 1.3 1.2 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter BTB PF00651.26 EME79247.1 - 9.5e-18 64.2 0.0 2.1e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SUI1 PF01253.17 EME79247.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2972 PF11186.3 EME79247.1 - 0.013 15.4 1.4 3.4 7.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) PTPlike_phytase PF14566.1 EME79247.1 - 0.018 15.1 0.2 0.031 14.3 0.1 1.3 1 1 0 1 1 1 0 Inositol hexakisphosphate Med27 PF11571.3 EME79247.1 - 0.058 13.5 0.6 0.13 12.4 0.4 1.7 1 1 0 1 1 1 0 Mediator complex subunit 27 M60-like PF13402.1 EME79247.1 - 0.1 11.4 0.1 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase M60-like family DUF4182 PF13790.1 EME79247.1 - 0.15 11.8 1.8 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) MFS_1 PF07690.11 EME79248.1 - 2e-21 76.1 24.9 2e-21 76.1 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME79248.1 - 0.00076 18.1 11.7 0.00076 18.1 8.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 EME79249.1 - 2e-36 125.4 0.0 3.7e-36 124.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MAPEG PF01124.13 EME79250.1 - 1.4e-15 57.0 0.3 1.6e-15 56.8 0.2 1.0 1 0 0 1 1 1 1 MAPEG family EST1 PF10374.4 EME79250.1 - 0.033 14.1 0.0 0.95 9.4 0.0 2.0 2 0 0 2 2 2 0 Telomerase activating protein Est1 Ribosomal_S3_C PF00189.15 EME79251.1 - 0.0076 16.4 0.2 0.019 15.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain LRR_4 PF12799.2 EME79252.1 - 0.0069 15.9 0.2 4.8 6.9 0.0 4.6 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) DUF3208 PF11482.3 EME79252.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Kinesin PF00225.18 EME79253.1 - 1.2e-24 86.7 0.1 8e-12 44.5 0.1 2.2 2 0 0 2 2 2 2 Kinesin motor domain G-alpha PF00503.15 EME79253.1 - 0.0037 15.9 0.0 0.004 15.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF87 PF01935.12 EME79253.1 - 0.0095 15.7 0.1 0.023 14.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function DUF87 eIF2A PF08662.6 EME79253.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Mg_chelatase PF01078.16 EME79253.1 - 0.09 11.9 0.0 0.44 9.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI HAD_2 PF13419.1 EME79256.1 - 1.1e-21 77.8 0.0 1.4e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EME79256.1 - 0.0016 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HipA_N PF07805.7 EME79256.1 - 0.023 14.8 0.0 0.56 10.4 0.0 2.6 2 1 1 3 3 3 0 HipA-like N-terminal domain Hydrolase PF00702.21 EME79256.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.13 EME79256.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DAO PF01266.19 EME79257.1 - 1.8e-30 106.0 0.2 2e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME79257.1 - 7.3e-05 22.7 0.3 0.00014 21.8 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME79257.1 - 0.00053 19.1 0.1 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EME79257.1 - 0.00057 20.0 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME79257.1 - 0.00096 18.9 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME79257.1 - 0.0047 16.8 0.2 0.006 16.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME79257.1 - 0.019 13.8 0.3 0.044 12.6 0.1 1.6 1 1 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EME79257.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EME79257.1 - 0.11 11.2 1.0 0.2 10.4 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain Malic_M PF03949.10 EME79257.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain RNase_P_p30 PF01876.11 EME79260.1 - 4.6e-41 139.5 0.0 5.7e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 zf-C2H2 PF00096.21 EME79262.1 - 0.0028 17.8 1.4 0.0028 17.8 1.0 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-BED PF02892.10 EME79262.1 - 0.017 14.8 0.8 0.048 13.4 0.0 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 EME79262.1 - 0.025 14.8 0.9 0.025 14.8 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME79262.1 - 0.033 14.3 0.3 0.1 12.7 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding IBR PF01485.16 EME79262.1 - 0.043 13.6 0.4 3 7.8 0.0 2.5 2 0 0 2 2 2 0 IBR domain zf-C2H2_6 PF13912.1 EME79262.1 - 0.16 11.9 0.4 0.16 11.9 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1771 PF08590.5 EME79263.1 - 1.1e-13 50.9 11.3 1.1e-13 50.9 7.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EME79263.1 - 1.1e-10 40.9 2.6 6.4e-05 22.5 0.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EME79263.1 - 3.8e-08 33.4 0.0 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EME79264.1 - 7.5e-21 73.3 35.3 5.7e-06 25.8 2.8 5.1 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Colipase-like PF15083.1 EME79264.1 - 0.054 13.4 4.6 8.4 6.4 0.7 3.1 1 1 1 2 2 2 0 Colipase-like CFEM PF05730.6 EME79266.1 - 2.6e-12 46.3 11.6 4e-12 45.7 8.0 1.3 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_16 PF00722.16 EME79267.1 - 2.8e-08 33.2 0.1 1.1e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Pectate_lyase_3 PF12708.2 EME79268.1 - 1.5e-71 241.0 13.0 7.9e-64 215.8 4.4 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EME79268.1 - 0.0052 16.2 0.5 0.032 13.7 0.1 2.3 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EME79268.1 - 2.3 7.9 16.6 0.47 10.2 5.8 3.3 2 2 0 2 2 2 0 Right handed beta helix region DMAP_binding PF06464.6 EME79269.1 - 3.7e-09 37.1 0.0 3.7e-09 37.1 0.0 2.9 3 0 0 3 3 3 1 DMAP1-binding Domain DUF2786 PF10979.3 EME79269.1 - 3.9e-08 32.8 0.1 3.9e-08 32.8 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2786) GvpG PF05120.7 EME79269.1 - 7e-05 22.5 0.0 7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Gas vesicle protein G Calreticulin PF00262.13 EME79270.1 - 4.4e-160 532.3 14.7 4.4e-160 532.3 10.2 1.4 2 0 0 2 2 2 1 Calreticulin family GTP_cyclohydroI PF01227.17 EME79271.1 - 1.2e-60 203.9 0.4 1.4e-60 203.6 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EME79271.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 QueF-like protein FAD_binding_4 PF01565.18 EME79272.1 - 1.3e-13 50.6 2.0 3.4e-13 49.2 0.1 2.7 3 1 0 3 3 3 1 FAD binding domain Phos_pyr_kin PF08543.7 EME79273.1 - 2.8e-12 46.3 0.0 6.5e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EME79273.1 - 1.3e-06 27.8 0.3 9.8e-06 24.9 0.2 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PCNA_N PF00705.13 EME79274.1 - 5.9e-54 180.9 4.2 8.9e-54 180.3 2.4 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EME79274.1 - 6.3e-52 174.8 0.0 5.8e-51 171.7 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EME79274.1 - 9.9e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EME79274.1 - 0.0012 17.8 0.2 0.0076 15.2 0.1 2.0 2 1 0 2 2 2 1 Hus1-like protein DUF2576 PF10845.3 EME79274.1 - 0.3 10.2 2.7 0.37 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Rab5ip PF07019.7 EME79275.1 - 7.4e-22 77.2 5.5 9.2e-22 76.9 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Nro1 PF12753.2 EME79276.1 - 0.0011 18.0 0.1 0.0014 17.6 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_14 PF13428.1 EME79276.1 - 0.14 12.8 9.1 11 6.9 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Vezatin PF12632.2 EME79277.1 - 9.3e-42 142.8 0.6 1.5e-41 142.1 0.4 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes UPF0118 PF01594.11 EME79277.1 - 0.032 13.2 2.6 0.061 12.3 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF20 TAS2R PF05296.8 EME79277.1 - 0.064 12.1 0.4 0.11 11.4 0.3 1.3 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) DUF3290 PF11694.3 EME79277.1 - 0.19 11.4 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) O-antigen_lig PF13425.1 EME79277.1 - 0.22 11.4 1.8 0.38 10.7 1.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FAD_binding_2 PF00890.19 EME79278.1 - 5.3e-73 246.2 0.1 1.6e-71 241.3 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EME79278.1 - 4.7e-18 64.7 0.6 1.4e-16 60.0 0.1 3.3 3 2 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_8 PF13450.1 EME79278.1 - 9.3e-10 38.4 0.3 6e-08 32.6 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME79278.1 - 2.2e-09 36.6 0.1 3.3e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME79278.1 - 3.6e-09 36.1 0.0 1.3e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME79278.1 - 4e-07 28.8 1.0 0.00099 17.6 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EME79278.1 - 2.1e-06 27.7 0.8 0.0008 19.3 0.6 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME79278.1 - 3.3e-05 23.0 0.3 0.005 15.9 0.1 2.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EME79278.1 - 7.9e-05 21.6 0.6 0.016 14.0 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME79278.1 - 0.00052 20.1 0.3 0.0022 18.0 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME79278.1 - 0.0084 15.1 0.4 0.013 14.5 0.3 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EME79278.1 - 0.031 14.0 0.0 0.16 11.7 0.0 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EME79278.1 - 0.052 12.6 0.1 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GDI PF00996.13 EME79278.1 - 0.18 10.1 0.1 0.28 9.4 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor AA_permease_2 PF13520.1 EME79281.1 - 2.4e-46 158.1 42.9 6.2e-46 156.8 29.7 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME79281.1 - 6.4e-32 110.5 29.3 6.4e-32 110.5 20.3 1.5 2 0 0 2 2 2 1 Amino acid permease MFS_1 PF07690.11 EME79282.1 - 1.8e-18 66.3 14.5 2.8e-18 65.7 10.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box PF00646.28 EME79285.1 - 8.2e-06 25.3 0.9 1.4e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME79285.1 - 0.0003 20.4 0.0 0.00076 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EME79285.1 - 0.026 14.2 0.2 0.098 12.3 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain DUF2418 PF10332.4 EME79286.1 - 1.1e-29 102.6 0.1 2.3e-29 101.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) AA_permease_2 PF13520.1 EME79286.1 - 0.058 11.9 0.0 0.098 11.1 0.0 1.3 1 0 0 1 1 1 0 Amino acid permease MFS_1 PF07690.11 EME79287.1 - 2.8e-16 59.1 58.0 2.2e-11 43.0 25.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2976 PF11190.3 EME79287.1 - 0.22 11.0 12.6 1 8.9 0.7 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) DUF2852 PF11014.3 EME79287.1 - 2.8 7.8 6.3 8.1 6.4 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DEAD PF00270.24 EME79288.1 - 1.6e-20 73.2 0.0 7.2e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME79288.1 - 9.3e-20 70.2 0.3 3e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME79288.1 - 1.8e-17 63.7 0.0 4.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME79288.1 - 0.025 14.7 0.0 0.15 12.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain GFA PF04828.9 EME79289.1 - 2.1e-15 56.4 0.0 3.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CN_hydrolase PF00795.17 EME79290.1 - 2.3e-34 118.3 0.0 2.9e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3430 PF11912.3 EME79292.1 - 0.0034 17.2 0.0 0.0042 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) CtIP_N PF10482.4 EME79293.1 - 0.055 13.2 1.8 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DEAD PF00270.24 EME79294.1 - 4.3e-25 88.1 0.0 8e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EME79294.1 - 4.6e-11 43.1 1.7 7.9e-10 39.1 1.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EME79294.1 - 3.3e-10 39.7 0.3 1.6e-09 37.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EME79294.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor CDT1 like SBP_bac_3 PF00497.15 EME79294.1 - 0.15 11.2 0.4 13 4.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 DUF4163 PF13739.1 EME79294.1 - 0.17 12.6 0.3 0.45 11.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Toxin_3 PF00537.13 EME79296.1 - 0.12 12.3 0.2 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Scorpion toxin-like domain Catalase PF00199.14 EME79297.1 - 5.2e-149 496.1 0.2 6.6e-149 495.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EME79297.1 - 2.8e-12 46.3 0.0 6.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Peptidase_M1 PF01433.15 EME79298.1 - 4.7e-12 45.7 0.0 0.00016 20.8 0.0 3.3 2 1 1 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 EME79298.1 - 0.0095 16.1 0.0 0.17 12.2 0.0 2.9 3 0 0 3 3 3 1 HEAT repeats Rad4 PF03835.10 EME79301.1 - 4.7e-35 120.1 0.5 4.7e-35 120.1 0.3 2.7 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EME79301.1 - 7e-28 96.1 0.0 1.4e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EME79301.1 - 5.4e-17 61.0 0.3 2.5e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EME79301.1 - 4e-15 55.8 0.3 4e-15 55.8 0.2 3.7 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EME79301.1 - 0.041 14.1 0.1 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Transglutaminase-like superfamily APH PF01636.18 EME79302.1 - 4.7e-36 124.7 0.0 9e-36 123.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EME79302.1 - 0.00015 21.0 0.0 0.00034 19.8 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EME79302.1 - 0.0058 15.9 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family CAP_GLY PF01302.20 EME79303.1 - 3.9e-17 61.6 2.0 5.6e-17 61.2 0.8 1.7 2 0 0 2 2 2 1 CAP-Gly domain AAA_13 PF13166.1 EME79303.1 - 0.0025 16.3 3.7 0.0025 16.3 2.6 1.8 2 0 0 2 2 2 1 AAA domain NPV_P10 PF05531.7 EME79303.1 - 0.057 13.6 3.6 0.51 10.6 0.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 EME79303.1 - 0.4 8.7 15.0 0.085 11.0 3.4 2.6 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA GAS PF13851.1 EME79303.1 - 0.64 9.1 21.3 0.43 9.7 0.1 3.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.8 EME79303.1 - 0.9 9.0 18.1 2.9 7.3 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Fzo_mitofusin PF04799.8 EME79303.1 - 1.5 8.1 7.4 0.28 10.5 2.1 2.0 2 0 0 2 2 2 0 fzo-like conserved region DUF3829 PF12889.2 EME79303.1 - 1.7 7.7 12.4 0.098 11.8 3.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3829) ATG16 PF08614.6 EME79303.1 - 2.7 7.7 24.5 0.034 13.9 0.5 3.4 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Sec8_exocyst PF04048.9 EME79303.1 - 2.7 7.6 11.7 0.37 10.4 1.2 3.2 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain PilJ PF13675.1 EME79303.1 - 3.4 8.0 13.6 0.12 12.7 1.8 3.4 2 2 3 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 EME79303.1 - 3.7 7.0 34.5 1.3e+02 2.1 1.9 3.9 1 1 1 2 2 2 0 IncA protein zf-CCHC_3 PF13917.1 EME79303.1 - 6 6.6 9.7 0.29 10.9 1.5 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF972 PF06156.8 EME79303.1 - 8.6 6.7 19.6 3.2 8.1 1.6 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 EME79303.1 - 9.1 6.0 28.4 0.032 13.9 3.3 3.5 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein End3 PF12761.2 EME79303.1 - 9.2 5.8 19.3 0.18 11.4 5.6 2.8 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Mnd1 PF03962.10 EME79303.1 - 9.4 5.8 22.4 0.13 11.9 1.1 3.5 2 1 2 4 4 4 0 Mnd1 family T2SF PF00482.18 EME79303.1 - 9.7 6.1 5.4 19 5.1 0.3 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Aminotran_1_2 PF00155.16 EME79304.1 - 9.2e-17 61.0 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EME79304.1 - 0.0011 17.5 0.0 0.0039 15.7 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 EME79304.1 - 0.0012 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DNA_pol_viral_C PF00336.13 EME79305.1 - 0.19 10.9 2.9 0.21 10.8 2.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain LSM PF01423.17 EME79306.1 - 1.9e-20 72.1 0.2 2.2e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain Aldedh PF00171.17 EME79309.1 - 2.8e-154 513.8 0.1 3.2e-154 513.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME79309.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Abhydrolase_6 PF12697.2 EME79310.1 - 1.8e-22 80.3 0.0 3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME79310.1 - 3.5e-13 49.6 0.0 4.3e-11 42.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME79310.1 - 8e-09 35.3 0.0 2.7e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADH_N PF08240.7 EME79313.1 - 4.7e-28 97.1 2.4 8.8e-28 96.2 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME79313.1 - 1.3e-18 66.8 0.1 1.9e-18 66.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME79313.1 - 0.0049 17.7 0.0 0.0089 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.1 EME79313.1 - 0.1 12.6 0.1 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Acyl_transf_3 PF01757.17 EME79314.1 - 1.3e-32 113.0 31.1 2.3e-32 112.1 21.6 1.4 1 1 0 1 1 1 1 Acyltransferase family EF-hand_1 PF00036.27 EME79315.1 - 2e-25 86.0 6.9 1.2e-07 30.4 0.2 5.0 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EME79315.1 - 3e-22 76.4 4.5 0.00016 21.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EME79315.1 - 1.6e-21 75.6 4.0 7.1e-12 44.7 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EME79315.1 - 3.1e-21 75.2 6.0 1.2e-10 41.4 0.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EME79315.1 - 1.5e-18 65.2 9.3 0.00053 19.2 0.3 4.7 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 EME79315.1 - 0.045 13.4 1.0 1.9 8.2 0.0 2.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Dynamitin PF04912.9 EME79316.1 - 1.4e-20 73.4 20.3 3.6e-17 62.2 14.1 3.8 1 1 0 1 1 1 1 Dynamitin DUF4611 PF15387.1 EME79316.1 - 0.041 14.0 22.9 1.8 8.7 1.8 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) Vfa1 PF08432.5 EME79316.1 - 0.34 10.8 16.8 0.062 13.3 0.7 3.7 4 0 0 4 4 4 0 AAA-ATPase Vps4-associated protein 1 AIP3 PF03915.8 EME79316.1 - 0.48 9.2 11.4 0.053 12.4 1.5 2.5 1 1 0 2 2 2 0 Actin interacting protein 3 Voldacs PF03517.8 EME79316.1 - 0.52 10.1 10.1 0.86 9.4 0.1 2.6 2 1 0 2 2 2 0 Regulator of volume decrease after cellular swelling Fmp27_WPPW PF10359.4 EME79316.1 - 2.2 6.6 13.5 0.17 10.2 0.1 3.2 4 0 0 4 4 4 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 EME79316.1 - 2.7 8.3 12.7 16 5.9 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EME79316.1 - 2.7 7.5 17.5 0.45 10.0 0.2 3.5 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.3 EME79316.1 - 3.2 7.6 20.0 1.2 8.9 1.1 3.4 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding SseC PF04888.7 EME79316.1 - 5.6 6.2 8.0 0.21 10.9 0.1 2.3 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family Spc24 PF08286.6 EME79316.1 - 7.3 6.3 22.9 0.64 9.7 2.3 3.6 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 FlxA PF14282.1 EME79316.1 - 9.1 6.2 15.0 2.3 8.1 0.1 4.0 4 0 0 4 4 4 0 FlxA-like protein Ricin_B_lectin PF00652.17 EME79317.1 - 3.7e-09 36.6 0.0 6.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Rhodanese PF00581.15 EME79319.1 - 3.4e-14 53.1 0.0 4.3e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain ECH PF00378.15 EME79320.1 - 7e-51 172.7 0.1 9e-51 172.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1838 PF08894.6 EME79320.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) FAD_binding_4 PF01565.18 EME79321.1 - 7.7e-16 57.8 0.3 5.1e-15 55.1 0.2 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME79321.1 - 1.2e-07 31.5 0.0 2.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M3 PF01432.15 EME79322.1 - 1.2e-158 529.0 0.0 1.7e-158 528.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 U-box PF04564.10 EME79323.1 - 3e-19 68.7 0.0 7e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EME79323.1 - 1.9e-16 59.4 7.0 4.4e-15 55.0 0.5 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME79323.1 - 5e-11 41.7 5.6 0.00074 19.0 0.6 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME79323.1 - 2.5e-10 39.4 5.4 0.00019 21.1 0.6 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME79323.1 - 8.9e-06 25.5 9.5 0.011 15.6 0.3 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME79323.1 - 1.2e-05 24.7 1.2 0.015 15.0 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME79323.1 - 1.8e-05 24.9 2.0 0.0015 18.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME79323.1 - 4.1e-05 24.1 0.4 4.1e-05 24.1 0.3 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat zf-Nse PF11789.3 EME79323.1 - 7.5e-05 22.1 0.2 0.00027 20.3 0.1 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_17 PF13431.1 EME79323.1 - 0.00014 21.8 3.6 0.6 10.4 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EME79323.1 - 0.00015 21.8 2.7 0.033 14.3 0.2 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EME79323.1 - 0.0034 17.8 7.8 0.081 13.5 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME79323.1 - 0.014 15.2 0.3 0.014 15.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EME79323.1 - 0.036 13.2 1.2 0.084 12.0 0.1 2.1 2 1 0 2 2 2 0 Coatomer epsilon subunit TPR_6 PF13174.1 EME79323.1 - 0.037 14.4 3.9 0.6 10.6 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME79323.1 - 0.22 11.3 2.4 9.3 6.2 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat YrhK PF14145.1 EME79324.1 - 0.13 11.9 21.2 0.2 11.3 0.4 4.5 3 1 0 3 3 3 0 YrhK-like protein UPF0220 PF05255.6 EME79324.1 - 3.2 6.9 7.7 5.6 6.1 1.7 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0220) TFIIS_M PF07500.9 EME79325.1 - 1.4e-24 86.3 1.9 2.9e-24 85.3 1.3 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EME79325.1 - 4.7e-16 58.1 5.9 8.1e-16 57.3 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EME79325.1 - 5.8e-14 51.3 0.1 1.1e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RRF PF01765.14 EME79326.1 - 4.9e-36 123.6 3.1 6.7e-36 123.2 2.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Mnd1 PF03962.10 EME79326.1 - 4.9 6.7 9.5 17 5.0 0.1 2.1 2 0 0 2 2 2 0 Mnd1 family WD40 PF00400.27 EME79327.1 - 1.7e-07 30.8 3.2 4.9e-07 29.3 0.2 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat GFA PF04828.9 EME79328.1 - 1.4e-10 40.9 1.9 2.2e-10 40.3 1.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CDC73 PF05179.9 EME79330.1 - 5e-49 167.1 0.0 7.5e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RP-C_C PF11800.3 EME79331.1 - 0.06 13.0 5.4 0.017 14.7 0.9 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region PsbJ PF01788.12 EME79331.1 - 0.23 11.0 0.1 0.5 9.9 0.1 1.5 1 0 0 1 1 1 0 PsbJ p450 PF00067.17 EME79333.1 - 3.2e-39 134.7 0.0 4.7e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Crp PF00325.15 EME79333.1 - 0.14 11.6 0.4 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Peroxidase_2 PF01328.12 EME79335.1 - 7.6e-18 64.2 0.0 1.3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 PWI PF01480.12 EME79337.1 - 2.1e-07 30.9 0.0 5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EME79337.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb2_5 PF04567.12 EME79337.1 - 0.025 14.5 0.1 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 RRM_6 PF14259.1 EME79337.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.15 EME79338.1 - 6.5e-11 41.5 7.9 6.5e-11 41.5 5.5 1.4 2 0 0 2 2 2 1 Ribosomal protein S21 SelB-wing_2 PF09106.6 EME79338.1 - 0.057 13.3 1.0 0.1 12.5 0.1 1.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Phage_Gp23 PF10669.4 EME79338.1 - 0.19 11.8 1.2 0.22 11.6 0.8 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Plasmid_stab_B PF10784.4 EME79339.1 - 0.015 14.8 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Plasmid stability protein LMBR1 PF04791.11 EME79340.1 - 1.7e-17 63.1 1.0 1.7e-17 63.1 0.7 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein Neurensin PF14927.1 EME79340.1 - 0.055 12.8 0.0 0.055 12.8 0.0 3.0 2 1 1 3 3 3 0 Neurensin CPSF_A PF03178.10 EME79341.1 - 2.4e-67 227.2 0.0 6.3e-66 222.6 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EME79341.1 - 5.9e-06 24.6 0.0 1.5e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoplasmin PF03066.10 EME79341.1 - 0.053 13.0 1.5 8.8 5.8 0.0 2.7 2 0 0 2 2 2 0 Nucleoplasmin CNH PF00780.17 EME79341.1 - 0.089 12.1 0.0 3.2 7.1 0.0 2.7 3 0 0 3 3 3 0 CNH domain Abhydrolase_6 PF12697.2 EME79345.1 - 0.00029 20.7 0.0 0.00037 20.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME79345.1 - 0.00029 20.5 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EME79345.1 - 0.00039 19.7 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EME79345.1 - 0.0019 17.9 0.0 0.0029 17.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EME79345.1 - 0.017 14.7 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EME79345.1 - 0.026 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 EME79345.1 - 0.032 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EME79345.1 - 0.11 11.9 0.0 0.3 10.4 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Antitoxin-MazE PF04014.13 EME79346.1 - 0.013 15.2 0.0 37 4.1 0.0 4.4 2 2 1 3 3 3 0 Antidote-toxin recognition MazE PEX-1N PF09262.6 EME79346.1 - 0.34 10.9 12.3 77 3.4 0.9 6.2 1 1 3 5 5 5 0 Peroxisome biogenesis factor 1, N-terminal DUF359 PF04019.7 EME79346.1 - 0.48 9.8 7.9 31 3.9 0.1 5.0 1 1 5 7 7 7 0 Protein of unknown function (DUF359) Plasmod_MYXSPDY PF07981.6 EME79346.1 - 1.9 8.2 20.3 7.3 6.4 0.3 5.9 6 0 0 6 6 6 0 Plasmodium repeat_MYXSPDY Ank_2 PF12796.2 EME79347.1 - 1.4e-30 105.4 6.8 5.6e-17 61.8 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME79347.1 - 2.6e-30 102.6 8.3 1.1e-07 31.2 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EME79347.1 - 8.7e-21 73.4 7.0 7.3e-08 32.4 0.0 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME79347.1 - 3e-18 65.7 9.0 7.5e-09 35.8 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME79347.1 - 7.6e-18 62.8 6.0 0.00028 20.8 0.2 4.9 5 0 0 5 5 5 3 Ankyrin repeat PmbA_TldD PF01523.11 EME79347.1 - 0.089 12.0 0.0 1.1 8.5 0.0 1.9 1 1 1 2 2 2 0 Putative modulator of DNA gyrase Sulfatase PF00884.18 EME79348.1 - 7.7e-55 186.2 0.2 1e-54 185.8 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EME79348.1 - 0.0065 15.8 0.1 0.3 10.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EME79348.1 - 0.093 11.1 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) MFS_1 PF07690.11 EME79349.1 - 4.9e-38 130.7 35.1 5.2e-38 130.6 23.7 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME79349.1 - 1.7e-11 43.3 10.6 1.7e-11 43.3 7.4 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 EME79349.1 - 0.0029 15.7 4.1 0.0029 15.7 2.8 1.9 2 1 0 2 2 2 1 Transmembrane secretion effector DUF3298 PF11738.3 EME79349.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) Amidase PF01425.16 EME79350.1 - 2.1e-75 254.2 0.5 1.1e-71 242.0 0.1 2.0 2 0 0 2 2 2 2 Amidase CorA PF01544.13 EME79351.1 - 0.007 15.4 1.1 0.0099 14.9 0.8 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 EME79351.1 - 0.024 13.1 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 FtsX PF02687.16 EME79351.1 - 0.071 12.8 0.2 0.098 12.4 0.1 1.1 1 0 0 1 1 1 0 FtsX-like permease family Pro-kuma_activ PF09286.6 EME79352.1 - 7.1e-40 136.3 0.7 1.9e-39 134.9 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME79352.1 - 1.1e-08 34.6 0.7 1.7e-08 33.9 0.5 1.3 1 0 0 1 1 1 1 Subtilase family Response_reg PF00072.19 EME79355.1 - 4.6e-12 45.9 0.0 5e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FAA_hydrolase PF01557.13 EME79356.1 - 1.1e-51 175.4 0.0 1.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GNAT_acetyltr_2 PF13718.1 EME79357.1 - 1.4e-80 269.2 0.0 2.5e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EME79357.1 - 7.4e-67 224.3 0.0 3.8e-66 222.0 0.0 2.3 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.6 EME79357.1 - 1.8e-39 133.3 0.0 5.2e-39 131.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EME79357.1 - 1.4e-31 108.5 0.2 5e-31 106.8 0.1 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EME79357.1 - 7.1e-05 22.9 0.0 0.00025 21.1 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME79357.1 - 0.066 13.2 0.1 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Glyco_transf_90 PF05686.7 EME79358.1 - 1.8e-15 56.5 0.3 2.3e-09 36.4 0.1 4.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Lactamase_B PF00753.22 EME79359.1 - 8.6e-07 28.7 0.1 2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME79359.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ADH_zinc_N PF00107.21 EME79360.1 - 8.5e-25 86.7 0.0 1.3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME79360.1 - 6.6e-22 77.3 0.9 1.2e-21 76.5 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME79360.1 - 0.00039 21.3 0.0 0.0008 20.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME79360.1 - 0.002 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME79360.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EME79360.1 - 0.0039 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EME79360.1 - 0.018 14.7 0.2 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EME79360.1 - 0.036 13.6 0.2 0.092 12.3 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EME79360.1 - 0.045 13.5 0.8 0.07 12.9 0.2 1.7 2 0 0 2 2 2 0 ThiF family Methyltransf_23 PF13489.1 EME79360.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME79360.1 - 0.072 13.6 0.2 0.23 12.0 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EME79360.1 - 0.084 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EME79360.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Acetyltransf_3 PF13302.1 EME79361.1 - 2.9e-34 118.2 0.0 3.6e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME79361.1 - 5.2e-09 36.2 0.0 0.00026 20.9 0.0 2.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME79361.1 - 8.8e-06 25.6 0.0 0.25 11.2 0.0 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME79361.1 - 1.7e-05 24.7 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME79361.1 - 0.054 13.6 0.0 0.089 12.9 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ADP_PFK_GK PF04587.10 EME79361.1 - 0.082 11.0 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Fungal_trans_2 PF11951.3 EME79362.1 - 1.3e-10 40.4 0.4 1.9e-10 39.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79362.1 - 2.4e-07 30.5 10.9 4.2e-07 29.7 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tenui_NCP PF04876.7 EME79362.1 - 0.17 11.3 0.1 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein DDE_Tnp_4 PF13359.1 EME79364.1 - 0.00023 20.7 0.0 0.00024 20.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF3g PF12353.3 EME79366.1 - 5.4e-40 136.2 2.7 7.4e-40 135.8 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EME79366.1 - 1.9e-17 62.6 0.0 3.2e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME79366.1 - 1.9e-13 50.2 0.0 4.1e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME79366.1 - 6.9e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coatomer_WDAD PF04053.9 EME79367.1 - 8.1e-163 542.3 0.0 2.2e-162 540.8 0.0 1.7 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EME79367.1 - 2.5e-45 150.8 9.0 2.1e-10 40.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EME79367.1 - 0.00037 18.7 3.9 0.032 12.3 0.1 3.9 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EME79367.1 - 0.0043 16.8 0.0 3.1 7.6 0.0 3.1 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EME79367.1 - 0.027 14.1 0.0 19 4.9 0.0 3.7 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A E1_DerP2_DerF2 PF02221.10 EME79368.1 - 1.7e-26 93.0 0.4 1.8e-26 92.9 0.3 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EME79368.1 - 0.00018 21.5 0.1 0.00062 19.8 0.1 1.8 1 1 0 1 1 1 1 ML-like domain ATP-synt_F PF01990.12 EME79369.1 - 3.3e-29 101.0 0.1 3.9e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit RPT PF13446.1 EME79369.1 - 0.075 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 A repeated domain in UCH-protein HATPase_c_3 PF13589.1 EME79370.1 - 7.8e-14 51.4 0.2 9.8e-14 51.1 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME79370.1 - 2.3e-13 49.7 0.1 2.8e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNARE_assoc PF09335.6 EME79371.1 - 2.9e-15 56.5 10.2 4.4e-14 52.7 4.0 2.8 3 1 0 3 3 3 2 SNARE associated Golgi protein DUF1049 PF06305.6 EME79371.1 - 0.39 10.2 0.0 0.39 10.2 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Lyase_1 PF00206.15 EME79373.1 - 1.6e-48 165.5 0.0 2.9e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EME79373.1 - 1.3e-22 79.5 0.2 1.1e-21 76.6 0.1 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.6 EME79373.1 - 0.001 18.9 0.3 0.0039 17.0 0.0 2.1 2 1 0 2 2 2 1 Adenylosuccinate lyase C-terminal MFS_1 PF07690.11 EME79374.1 - 2.1e-11 43.1 30.7 3.4e-11 42.4 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EME79374.1 - 1e-10 41.3 8.8 3.2e-10 39.7 6.1 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DHH PF01368.15 EME79376.1 - 6e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 EME79376.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 DHHA2 domain Hist_deacetyl PF00850.14 EME79380.1 - 3.1e-41 141.6 0.1 1.5e-33 116.4 0.0 2.8 1 1 1 2 2 2 2 Histone deacetylase domain DnaJ PF00226.26 EME79382.1 - 0.025 14.3 0.0 0.075 12.7 0.0 1.9 1 0 0 1 1 1 0 DnaJ domain DUF4407 PF14362.1 EME79382.1 - 0.2 10.5 2.5 0.29 10.0 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SYCE1 PF15233.1 EME79382.1 - 0.23 11.3 4.0 0.48 10.3 2.8 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 OmpH PF03938.9 EME79382.1 - 2.6 7.9 6.1 6 6.7 4.2 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Dpy-30 PF05186.8 EME79383.1 - 4.4e-14 51.6 0.6 2.2e-13 49.4 0.2 1.9 2 0 0 2 2 2 1 Dpy-30 motif Peroxin-13_N PF04088.8 EME79385.1 - 3.8e-57 192.6 0.3 6.1e-57 191.9 0.2 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EME79385.1 - 7.9e-09 34.8 0.0 1.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME79385.1 - 3.9e-08 32.5 0.0 8.5e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain GRP PF07172.6 EME79385.1 - 1.1 9.8 20.2 2.4 8.6 14.0 1.6 1 0 0 1 1 1 0 Glycine rich protein family DUF2401 PF10287.4 EME79386.1 - 6.1e-89 297.5 0.8 6.1e-89 297.5 0.6 1.9 1 1 1 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EME79386.1 - 2.3e-25 88.4 1.0 4.3e-25 87.6 0.2 1.8 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Glyco_transf_22 PF03901.12 EME79387.1 - 6.6e-32 111.0 13.2 1e-31 110.4 9.1 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Yos1 PF08571.5 EME79388.1 - 3.9e-31 106.9 0.4 4.5e-31 106.7 0.3 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.24 EME79389.1 - 8.5e-64 215.2 0.0 1.4e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME79389.1 - 4.1e-31 108.5 0.6 3.5e-24 85.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Dscam_C PF12355.3 EME79389.1 - 0.35 11.1 11.4 0.023 14.9 2.0 2.7 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Peptidase_C98 PF15499.1 EME79389.1 - 0.43 9.8 10.8 0.032 13.5 0.9 2.6 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Borrelia_P83 PF05262.6 EME79389.1 - 0.52 8.5 10.0 0.89 7.7 7.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein SMN PF06003.7 EME79389.1 - 3.9 6.5 17.0 0.17 10.9 6.1 2.4 1 1 1 2 2 2 0 Survival motor neuron protein (SMN) Ycf1 PF05758.7 EME79389.1 - 8.1 4.0 7.2 12 3.4 5.0 1.2 1 0 0 1 1 1 0 Ycf1 Amino_oxidase PF01593.19 EME79391.1 - 5.7e-87 292.6 0.0 1.6e-86 291.1 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EME79391.1 - 1.2e-11 44.6 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EME79391.1 - 1.5e-06 28.1 0.0 5.3e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EME79391.1 - 2.9e-05 24.2 2.0 0.0021 18.2 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.19 EME79391.1 - 0.0038 16.1 0.6 0.02 13.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME79391.1 - 0.12 12.1 0.2 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding G-patch_2 PF12656.2 EME79392.1 - 0.15 11.9 2.2 0.2 11.5 0.5 2.0 1 1 1 2 2 2 0 DExH-box splicing factor binding site NTR2 PF15458.1 EME79393.1 - 4.2e-58 196.5 22.0 5.8e-58 196.1 15.3 1.2 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF2046 PF09755.4 EME79393.1 - 0.0017 17.2 1.1 0.0017 17.2 0.8 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein H4 (DUF2046) ATP-grasp_4 PF13535.1 EME79393.1 - 0.028 14.1 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Complex1_49kDa PF00346.14 EME79395.1 - 8.5e-133 441.4 0.0 1.1e-132 441.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EME79395.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.21 EME79396.1 - 4.1e-22 78.4 0.0 5.5e-21 74.8 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EME79396.1 - 4.3e-12 44.9 0.0 6.2e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_S8 PF00082.17 EME79398.1 - 1.6e-52 178.4 18.0 1.9e-52 178.1 12.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EME79398.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 DHO_dh PF01180.16 EME79401.1 - 4.2e-65 219.6 0.1 1.2e-51 175.4 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EME79401.1 - 0.0058 15.9 0.3 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EME79401.1 - 0.02 13.7 0.1 0.38 9.5 0.1 2.3 2 1 0 2 2 2 0 FMN-dependent dehydrogenase RabGAP-TBC PF00566.13 EME79404.1 - 4.4e-36 124.3 0.0 2.3e-28 99.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.15 EME79405.1 - 1.2e-73 247.5 12.1 2e-73 246.8 8.4 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EME79405.1 - 1e-31 108.4 2.6 1e-31 108.4 1.8 3.2 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EME79405.1 - 2.7e-09 36.4 0.0 5.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EME79405.1 - 2.4 7.9 8.6 0.14 11.9 1.0 2.8 3 0 0 3 3 3 0 Stannin transmembrane PigN PF04987.9 EME79407.1 - 1.2e-154 515.2 24.4 1.7e-154 514.7 16.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EME79407.1 - 3.3e-09 36.5 0.8 1.6e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME79407.1 - 5.1e-08 32.4 0.1 8.1e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EME79407.1 - 0.00023 20.6 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Lon_C PF05362.8 EME79408.1 - 2e-61 206.9 0.0 6.2e-61 205.2 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EME79408.1 - 1.2e-36 126.3 0.6 2.5e-36 125.2 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EME79408.1 - 4.2e-22 78.7 0.0 1.5e-21 76.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME79408.1 - 5.5e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME79408.1 - 1.8e-06 27.9 0.0 6.1e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EME79408.1 - 1.3e-05 24.6 0.0 3.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EME79408.1 - 1.7e-05 24.9 0.1 0.00058 20.0 0.0 3.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME79408.1 - 6.8e-05 22.0 0.0 0.00096 18.2 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EME79408.1 - 7.6e-05 21.5 0.0 0.00016 20.4 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 EME79408.1 - 9.1e-05 23.2 0.0 0.00048 20.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EME79408.1 - 0.00035 20.5 0.4 0.0033 17.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EME79408.1 - 0.0035 17.2 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME79408.1 - 0.021 14.2 0.2 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein SKI PF01202.17 EME79408.1 - 0.031 14.1 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.1 EME79408.1 - 0.047 13.9 4.6 0.078 13.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.10 EME79408.1 - 0.051 13.2 0.1 0.58 9.8 0.0 2.5 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 EME79408.1 - 0.059 13.5 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EME79408.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EME79408.1 - 0.073 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EME79408.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EME79408.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EME79408.1 - 0.12 11.8 0.1 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EME79408.1 - 0.12 11.8 0.0 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain Gastrin PF00918.12 EME79408.1 - 0.12 13.1 1.3 1 10.1 0.1 2.9 3 0 0 3 3 3 0 Gastrin/cholecystokinin family ABC_tran PF00005.22 EME79408.1 - 4.3 7.6 6.0 0.61 10.3 0.0 2.5 3 1 0 3 3 2 0 ABC transporter Ring_hydroxyl_A PF00848.14 EME79409.1 - 3.9e-32 111.6 4.6 2.3e-31 109.0 3.2 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EME79409.1 - 4.1e-17 61.5 0.0 9.1e-17 60.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UPF0079 PF02367.12 EME79409.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NAD_binding_2 PF03446.10 EME79411.1 - 1.4e-32 112.7 0.0 2.5e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME79411.1 - 1.6e-12 47.7 0.2 3.6e-12 46.5 0.1 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EME79411.1 - 8.5e-11 41.9 0.1 1.3e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EME79411.1 - 4.6e-10 39.7 0.0 9.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 EME79411.1 - 4.4e-05 22.4 0.1 7.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh_N PF03721.9 EME79411.1 - 0.0011 18.4 0.2 0.0034 16.7 0.1 1.8 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EME79411.1 - 0.0014 17.7 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EME79411.1 - 0.0073 16.2 0.3 0.023 14.6 0.2 1.9 1 1 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EME79411.1 - 0.0088 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EME79411.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EME79411.1 - 0.036 14.5 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PALP PF00291.20 EME79412.1 - 2.6e-60 204.2 0.4 3.7e-60 203.7 0.1 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EME79412.1 - 1.4e-10 40.8 0.0 4.8e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 CBS domain Erg28 PF03694.8 EME79413.1 - 4.2e-39 133.0 0.2 5.6e-39 132.5 0.2 1.2 1 0 0 1 1 1 1 Erg28 like protein DUF4532 PF15046.1 EME79413.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) adh_short PF00106.20 EME79414.1 - 5.8e-23 81.6 0.0 8.3e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME79414.1 - 1.3e-14 54.5 0.0 1.8e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME79414.1 - 2.1e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME79414.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME79414.1 - 0.017 14.0 0.1 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EME79414.1 - 0.021 14.9 0.1 0.045 13.8 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bromodomain PF00439.20 EME79415.1 - 1.8e-34 117.5 1.0 1.8e-18 66.1 0.4 2.6 2 0 0 2 2 2 2 Bromodomain DUF3313 PF11769.3 EME79415.1 - 0.082 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) SpoVG PF04026.7 EME79415.1 - 0.11 12.5 0.0 0.65 10.0 0.0 2.2 2 0 0 2 2 2 0 SpoVG LMP PF04778.7 EME79415.1 - 0.12 12.1 1.1 0.24 11.1 0.8 1.5 1 0 0 1 1 1 0 LMP repeated region Ank_2 PF12796.2 EME79417.1 - 3.1e-74 245.3 15.6 4e-18 65.5 0.2 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EME79417.1 - 5.5e-37 123.7 11.4 2.6e-06 26.9 0.1 7.6 7 0 0 7 7 7 6 Ankyrin repeat SF3b1 PF08920.5 EME79417.1 - 3.4e-31 108.2 0.6 7.7e-31 107.0 0.4 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 Ank_4 PF13637.1 EME79417.1 - 2.6e-27 94.6 0.1 7.8e-07 29.4 0.0 5.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME79417.1 - 5.4e-26 88.0 1.2 0.005 16.9 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EME79417.1 - 2e-23 81.9 11.0 0.00016 21.8 0.1 7.4 2 2 5 7 7 7 5 Ankyrin repeats (many copies) HEAT_2 PF13646.1 EME79417.1 - 5.7e-15 55.3 2.0 0.013 15.7 0.0 7.7 5 3 2 8 8 8 4 HEAT repeats HEAT PF02985.17 EME79417.1 - 8.4e-11 41.0 7.9 0.21 11.7 0.1 9.3 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EME79417.1 - 1.3e-10 41.3 0.6 1.1 9.8 0.0 8.2 7 2 2 9 9 8 2 HEAT-like repeat Adaptin_N PF01602.15 EME79417.1 - 3.5e-05 22.3 0.6 0.082 11.2 0.0 3.2 3 0 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EME79417.1 - 5.9e-05 23.3 0.2 1.6 9.1 0.0 5.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EME79417.1 - 0.0071 15.7 0.2 1.2 8.4 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 EME79417.1 - 0.0071 15.7 0.4 12 5.1 0.0 4.3 4 0 0 4 4 4 0 NUC173 domain Pkinase PF00069.20 EME79419.1 - 1.5e-54 184.9 0.0 1.9e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79419.1 - 9.6e-36 123.1 0.0 1.6e-35 122.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME79419.1 - 2e-05 23.6 0.0 5.6e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EME79419.1 - 0.015 14.3 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME79419.1 - 0.019 14.6 0.0 3.6 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family TIP41 PF04176.8 EME79421.1 - 1.5e-69 232.8 0.6 1.9e-69 232.5 0.4 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EME79422.1 - 8e-70 234.9 0.0 1e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79422.1 - 2.6e-43 147.9 0.0 3.5e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME79422.1 - 1.9e-08 33.6 0.0 3e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EME79422.1 - 7.4e-05 21.8 0.1 0.00015 20.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EME79422.1 - 0.01 15.2 0.1 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EME79422.1 - 0.046 13.4 0.0 0.098 12.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EME79423.1 - 3.8e-65 218.5 0.6 4.7e-65 218.2 0.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EME79423.1 - 0.003 17.2 1.8 0.005 16.5 0.8 1.6 1 1 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EME79423.1 - 0.026 14.5 0.4 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily MFS_1 PF07690.11 EME79424.1 - 1.8e-29 102.5 25.0 1.8e-29 102.5 17.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 EME79425.1 - 2.7e-51 174.5 0.2 3.5e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME79425.1 - 1.8e-07 31.0 0.8 4.3e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME79425.1 - 6.7e-05 23.0 0.2 0.2 11.6 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME79425.1 - 0.0069 15.4 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME79425.1 - 0.016 14.0 0.5 0.028 13.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DUF1445 PF07286.7 EME79426.1 - 2.5e-53 179.5 0.0 3.5e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) NmrA PF05368.8 EME79427.1 - 1.3e-07 31.1 0.0 2.7e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME79427.1 - 2.6e-05 24.3 0.0 5.8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME79427.1 - 0.0031 16.4 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EME79427.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EME79427.1 - 0.065 12.6 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EME79427.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ctr PF04145.10 EME79429.1 - 4.9e-34 117.4 2.9 6.4e-34 117.0 2.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family WD40 PF00400.27 EME79430.1 - 3.9e-26 89.9 7.5 6e-07 29.1 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 EME79430.1 - 5.6e-05 21.4 2.5 0.035 12.2 0.1 3.0 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EME79430.1 - 0.001 19.2 0.1 0.01 16.0 0.0 2.7 2 0 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 EME79430.1 - 0.0013 17.6 0.0 5.5 5.6 0.0 3.7 1 1 3 4 4 4 2 Nup133 N terminal like DUF2844 PF11005.3 EME79430.1 - 0.075 12.8 0.3 0.3 10.8 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2844) ACPS PF01648.15 EME79432.1 - 3.4e-11 42.9 0.3 1e-10 41.4 0.2 1.8 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Acyl_transf_3 PF01757.17 EME79433.1 - 1.1e-31 109.9 24.4 1.4e-31 109.6 16.9 1.2 1 0 0 1 1 1 1 Acyltransferase family PBP1_TM PF14812.1 EME79434.1 - 0.071 13.4 0.1 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gly_transf_sug PF04488.10 EME79435.1 - 6.7e-06 26.4 0.0 1.9e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Neur_chan_LBD PF02931.18 EME79435.1 - 0.088 11.9 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain TPT PF03151.11 EME79438.1 - 4.5e-22 78.3 11.5 4.5e-22 78.3 8.0 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME79438.1 - 1.1e-11 44.1 18.2 2.6e-11 42.9 12.6 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME79438.1 - 0.0099 15.9 8.3 0.0099 15.9 5.8 2.7 2 1 0 3 3 3 2 EamA-like transporter family SyrA PF11089.3 EME79438.1 - 0.012 15.4 0.9 0.063 13.0 0.1 2.6 2 0 0 2 2 2 0 Exopolysaccharide production repressor UDPG_MGDP_dh_C PF03720.10 EME79439.1 - 1e-29 102.8 0.0 9.9e-26 89.9 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EME79439.1 - 3.8e-24 84.7 0.0 7.1e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain CFEM PF05730.6 EME79440.1 - 9.6e-13 47.7 10.8 1.8e-12 46.8 7.5 1.4 1 0 0 1 1 1 1 CFEM domain PAT1 PF09770.4 EME79440.1 - 2.1 6.4 20.2 2.5 6.2 14.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EME79440.1 - 4.6 6.5 26.8 5.6 6.2 18.6 1.1 1 0 0 1 1 1 0 Vta1 like Acyl_transf_3 PF01757.17 EME79441.1 - 5e-29 101.2 33.9 6.5e-29 100.8 23.5 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF3431 PF11913.3 EME79442.1 - 5.8e-65 218.8 0.0 9e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Lipase_GDSL_2 PF13472.1 EME79443.1 - 9.1e-14 51.9 0.9 2e-13 50.8 0.7 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME79443.1 - 1.4e-09 38.1 0.4 4.1e-09 36.6 0.3 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sigma70_ner PF04546.8 EME79444.1 - 0.53 9.8 4.9 0.11 12.1 1.3 1.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Atg14 PF10186.4 EME79445.1 - 8.9e-52 175.9 0.2 1.1e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EME79445.1 - 0.033 13.2 0.6 0.056 12.4 0.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EME79445.1 - 0.057 13.0 4.6 0.1 12.2 3.2 1.3 1 0 0 1 1 1 0 Mnd1 family GRA6 PF05084.8 EME79445.1 - 0.085 12.3 1.8 0.16 11.4 1.2 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) SAS4 PF15460.1 EME79447.1 - 3.2e-33 113.6 3.9 6.4e-33 112.6 2.7 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Astacin PF01400.19 EME79448.1 - 0.00023 20.6 0.5 0.00068 19.0 0.4 1.7 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) Reprolysin_4 PF13583.1 EME79448.1 - 0.0043 16.6 0.5 0.0075 15.8 0.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EME79448.1 - 0.0097 15.9 0.2 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EME79448.1 - 0.04 13.8 0.4 0.061 13.2 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EME79448.1 - 0.062 13.0 2.5 0.13 11.9 1.7 1.7 1 1 0 1 1 1 0 Matrixin RPAP2_Rtr1 PF04181.8 EME79449.1 - 4.8e-15 55.4 1.3 1.1e-14 54.2 0.4 2.1 2 1 0 2 2 2 1 Rtr1/RPAP2 family SH3_1 PF00018.23 EME79451.1 - 7.2e-11 41.3 0.2 1.8e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME79451.1 - 3.8e-09 35.9 0.2 1.1e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EME79451.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NDT80_PhoG PF05224.7 EME79453.1 - 2.2e-38 132.1 0.5 6.2e-38 130.6 0.3 1.7 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family SRPRB PF09439.5 EME79454.1 - 3.2e-35 120.9 0.0 1.7e-34 118.6 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EME79454.1 - 1.7e-06 27.9 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EME79454.1 - 9.4e-06 24.9 0.0 0.00012 21.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EME79454.1 - 0.00026 21.4 0.0 0.0016 18.9 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EME79454.1 - 0.00037 19.9 0.0 0.0013 18.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME79454.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EME79454.1 - 0.001 18.5 0.2 0.0023 17.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 EME79454.1 - 0.0011 18.0 0.0 0.0039 16.2 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_16 PF13191.1 EME79454.1 - 0.0031 17.5 0.7 0.0054 16.7 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EME79454.1 - 0.0031 17.7 0.1 0.005 17.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.12 EME79454.1 - 0.0034 16.9 0.4 0.39 10.2 0.0 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EME79454.1 - 0.0045 16.8 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME79454.1 - 0.0057 15.8 0.2 0.024 13.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EME79454.1 - 0.015 14.7 0.0 0.3 10.5 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EME79454.1 - 0.016 15.3 0.1 0.027 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EME79454.1 - 0.023 14.8 0.3 0.057 13.6 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME79454.1 - 0.024 14.3 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ras PF00071.17 EME79454.1 - 0.03 13.7 0.0 0.13 11.6 0.0 1.9 1 1 0 1 1 1 0 Ras family MobB PF03205.9 EME79454.1 - 0.035 13.8 0.3 0.28 10.9 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EME79454.1 - 0.049 13.9 0.1 0.061 13.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EME79454.1 - 0.049 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME79454.1 - 0.073 13.8 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EME79454.1 - 0.073 12.1 0.1 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EME79454.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF927 PF06048.6 EME79454.1 - 0.75 9.0 2.6 1.1 8.4 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF927) WLM PF08325.5 EME79455.1 - 9e-49 165.8 0.2 1.7e-48 164.9 0.2 1.6 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EME79455.1 - 0.0095 15.0 3.7 0.019 14.0 2.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Thiolase_N PF00108.18 EME79456.1 - 2.2e-65 220.2 0.1 3.1e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME79456.1 - 2.7e-38 130.1 0.0 5e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME79456.1 - 0.055 12.9 1.1 0.11 11.8 0.4 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ribosomal_S13_N PF08069.7 EME79457.1 - 2.5e-29 100.8 0.2 4.7e-29 100.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EME79457.1 - 1.5e-22 79.1 0.0 2.3e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EME79457.1 - 0.0093 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 'Paired box' domain Ecm33 PF12454.3 EME79458.1 - 0.00054 19.7 5.0 0.01 15.6 0.2 3.0 2 1 0 2 2 2 2 GPI-anchored cell wall organization protein Pex14_N PF04695.8 EME79458.1 - 3.5 7.6 5.6 4 7.4 0.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region p450 PF00067.17 EME79459.1 - 9.4e-57 192.5 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PX PF00787.19 EME79460.1 - 1.5e-19 69.8 3.1 2.8e-19 68.9 0.1 2.6 3 1 0 3 3 3 1 PX domain Vps5 PF09325.5 EME79460.1 - 3.1e-13 49.5 10.3 9.1e-07 28.3 0.2 2.1 1 1 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EME79460.1 - 3e-06 26.8 6.8 6.9e-06 25.7 4.7 1.6 1 1 0 1 1 1 1 BAR domain Reo_sigmaC PF04582.7 EME79460.1 - 0.0047 16.1 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein IncA PF04156.9 EME79460.1 - 0.018 14.6 3.6 0.29 10.7 0.0 2.2 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EME79460.1 - 0.16 10.9 4.2 2.9 6.8 1.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 EME79460.1 - 0.4 10.5 4.9 3.7 7.4 0.4 2.9 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.15 EME79460.1 - 0.88 9.3 7.2 23 4.8 0.0 3.2 3 0 0 3 3 3 0 Prefoldin subunit TerB PF05099.8 EME79460.1 - 3.6 7.3 9.2 1.3 8.7 1.5 2.5 3 0 0 3 3 3 0 Tellurite resistance protein TerB Lebercilin PF15619.1 EME79461.1 - 2.4e-05 23.8 17.6 2.4e-05 23.8 12.2 2.4 2 0 0 2 2 1 1 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.5 EME79461.1 - 0.00078 19.5 10.7 0.00078 19.5 7.4 2.7 2 1 2 4 4 3 1 Fibrinogen alpha/beta chain family DUF2935 PF11155.3 EME79461.1 - 0.0034 17.4 2.7 0.0076 16.3 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2935) Matrilin_ccoil PF10393.4 EME79461.1 - 0.0034 16.7 1.8 0.0034 16.7 1.2 2.9 3 0 0 3 3 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Reo_sigmaC PF04582.7 EME79461.1 - 0.0052 16.0 10.4 0.14 11.3 0.2 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Laminin_II PF06009.7 EME79461.1 - 0.017 14.8 3.9 0.017 14.8 2.7 3.7 2 2 2 4 4 3 0 Laminin Domain II DUF972 PF06156.8 EME79461.1 - 0.021 15.1 23.1 0.19 12.0 1.2 4.1 2 2 1 3 3 3 0 Protein of unknown function (DUF972) RmuC PF02646.11 EME79461.1 - 0.026 13.3 13.0 0.079 11.7 1.3 3.0 1 1 2 3 3 3 0 RmuC family Syntaxin-6_N PF09177.6 EME79461.1 - 0.027 14.8 17.7 0.61 10.5 1.6 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EME79461.1 - 0.041 14.1 15.4 1.2 9.4 0.7 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MtrG PF04210.8 EME79461.1 - 0.051 13.2 2.5 3.1 7.5 0.1 3.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Syntaxin_2 PF14523.1 EME79461.1 - 0.074 13.0 10.6 0.8 9.7 3.3 2.8 1 1 1 2 2 2 0 Syntaxin-like protein MbeD_MobD PF04899.7 EME79461.1 - 0.092 12.6 10.3 0.4 10.6 0.4 4.0 1 1 2 4 4 4 0 MbeD/MobD like Baculo_PEP_C PF04513.7 EME79461.1 - 0.1 12.4 12.7 0.072 12.9 2.9 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.11 EME79461.1 - 0.19 11.1 5.8 1.1 8.7 0.5 3.4 3 1 0 3 3 3 0 Chordopoxvirus fusion protein DUF948 PF06103.6 EME79461.1 - 0.29 11.0 14.7 0.7 9.7 1.5 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1216 PF06746.6 EME79461.1 - 0.38 10.5 8.2 0.5 10.1 4.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) TBPIP PF07106.8 EME79461.1 - 0.4 10.1 19.2 0.19 11.2 7.9 2.7 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF677 PF05055.7 EME79461.1 - 0.42 9.2 14.2 0.043 12.4 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF677) DUF1664 PF07889.7 EME79461.1 - 0.51 10.1 18.0 0.75 9.5 0.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.4 EME79461.1 - 0.66 9.9 10.9 0.3 11.0 4.6 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 EME79461.1 - 0.8 9.2 23.3 7.1 6.1 2.6 3.0 1 1 1 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EME79461.1 - 1.8 8.7 17.3 2.7 8.1 0.7 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 EME79461.1 - 2.2 9.0 11.3 6.1 7.6 0.3 3.9 1 1 2 3 3 3 0 Occludin homology domain Hemerythrin PF01814.18 EME79461.1 - 3.2 7.9 10.5 1.4e+02 2.5 7.3 3.2 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Dor1 PF04124.7 EME79461.1 - 3.8 5.8 12.8 1.2 7.5 5.1 2.2 1 1 1 2 2 2 0 Dor1-like family DEAD PF00270.24 EME79462.1 - 9.7e-44 148.8 2.2 1.3e-43 148.4 1.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME79462.1 - 1.3e-27 95.5 0.3 6.2e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME79462.1 - 0.0026 17.6 0.0 0.0055 16.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EME79462.1 - 0.0031 17.1 0.1 0.011 15.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME79462.1 - 0.01 15.9 0.1 0.034 14.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EME79462.1 - 0.016 14.2 0.3 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EME79462.1 - 0.021 14.5 0.1 0.071 12.8 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain UvrD-helicase PF00580.16 EME79462.1 - 0.057 12.7 0.1 0.19 11.0 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain CobA_CobO_BtuR PF02572.10 EME79462.1 - 0.064 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 EME79462.1 - 0.087 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein Flavi_DEAD PF07652.9 EME79462.1 - 0.11 12.2 0.1 0.57 9.9 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.1 EME79463.1 - 3.8e-15 56.0 0.0 1.9e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EME79463.1 - 8.4e-09 35.6 0.2 0.00042 20.5 0.0 2.5 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.2 EME79463.1 - 2.9e-08 33.3 0.2 5.9e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME79463.1 - 4.7e-06 26.1 0.1 1.1e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain LIP PF03583.9 EME79464.1 - 5.2e-75 252.3 0.8 7e-75 251.9 0.6 1.1 1 0 0 1 1 1 1 Secretory lipase 2Fe-2S_Ferredox PF11591.3 EME79465.1 - 0.55 9.9 6.1 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Ferredoxin chloroplastic transit peptide DUF4491 PF14898.1 EME79466.1 - 0.12 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) DUF2263 PF10021.4 EME79467.1 - 1.1e-18 67.6 0.0 2.1e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EME79467.1 - 0.019 14.8 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Macro domain Lactamase_B PF00753.22 EME79468.1 - 3.5e-06 26.8 1.2 4.8e-06 26.3 0.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily AMP-binding PF00501.23 EME79470.1 - 1.1e-73 247.9 0.0 2e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EME79470.1 - 1.8e-70 237.3 0.0 3.8e-70 236.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EME79470.1 - 1.1e-52 179.3 0.0 2.8e-52 178.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EME79470.1 - 8.6e-49 166.2 0.1 2e-48 165.0 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EME79470.1 - 1.1e-45 155.8 0.0 1.7e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EME79470.1 - 4.9e-44 150.1 0.0 2e-43 148.1 0.0 2.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EME79470.1 - 6.9e-39 133.4 0.6 4.5e-37 127.5 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EME79470.1 - 2.4e-26 91.9 0.0 1.3e-25 89.5 0.0 2.4 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EME79470.1 - 1.6e-21 76.3 0.0 1.4e-20 73.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EME79470.1 - 7.7e-17 61.5 0.0 2.7e-16 59.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EME79470.1 - 8.3e-12 45.2 1.7 5.7e-05 23.3 0.1 3.1 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EME79470.1 - 1.7e-11 44.4 0.0 4.4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME79470.1 - 8.3e-11 41.8 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EME79470.1 - 8.2e-10 38.8 0.0 4.2e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 HxxPF-repeated domain Epimerase PF01370.16 EME79470.1 - 8.4e-10 38.4 0.0 5.5e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EME79470.1 - 1.1e-07 31.5 0.0 1.1e-06 28.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME79470.1 - 4.7e-07 29.1 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EME79470.1 - 1.7e-05 25.3 0.0 0.00016 22.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EME79470.1 - 0.00099 17.8 0.0 0.74 8.4 0.0 2.7 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 EME79470.1 - 0.001 18.0 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_8 PF05148.10 EME79470.1 - 0.0091 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Glyco_trans_4_2 PF13477.1 EME79470.1 - 0.6 9.9 0.0 3.1 7.6 0.0 2.2 2 0 0 2 2 1 0 Glycosyl transferase 4-like ADH_zinc_N PF00107.21 EME79471.1 - 8.6e-08 31.7 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME79471.1 - 7.6e-05 22.4 0.1 0.00024 20.8 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EME79472.1 - 5.3e-70 236.2 0.0 6.4e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_4 PF01063.14 EME79473.1 - 1.4e-20 73.7 0.0 2.1e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ABC_membrane PF00664.18 EME79474.1 - 2.2e-87 292.9 31.5 2.1e-46 158.5 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME79474.1 - 3.7e-69 231.3 0.0 1.1e-34 119.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME79474.1 - 5e-12 45.5 3.9 0.001 18.3 0.2 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME79474.1 - 7.4e-11 42.5 0.5 0.031 14.2 0.0 4.2 2 2 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EME79474.1 - 5.4e-10 38.4 1.4 0.0013 17.4 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EME79474.1 - 2e-08 35.1 0.0 0.013 16.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EME79474.1 - 2.8e-08 33.1 0.3 0.00068 19.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EME79474.1 - 1.3e-07 31.7 4.0 0.0014 18.6 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EME79474.1 - 1.9e-06 27.4 0.1 0.023 14.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EME79474.1 - 6.9e-06 26.1 0.0 0.055 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EME79474.1 - 7.8e-06 25.1 0.1 0.093 11.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 EME79474.1 - 3.4e-05 23.7 0.0 0.23 11.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 EME79474.1 - 5.6e-05 23.2 3.4 0.3 11.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EME79474.1 - 0.00017 21.8 0.1 0.41 10.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EME79474.1 - 0.00044 19.7 3.8 0.7 9.2 0.3 4.4 4 0 0 4 4 4 1 AAA-like domain APS_kinase PF01583.15 EME79474.1 - 0.0015 18.2 0.7 0.51 9.9 0.0 3.3 3 0 0 3 3 3 1 Adenylylsulphate kinase SbcCD_C PF13558.1 EME79474.1 - 0.0021 17.9 2.8 1.5 8.7 0.2 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EME79474.1 - 0.0023 17.7 0.0 2.7 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EME79474.1 - 0.0066 15.9 0.2 0.84 9.0 0.0 2.9 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EME79474.1 - 0.0084 15.8 3.9 0.86 9.3 0.0 3.8 4 0 0 4 4 3 1 Part of AAA domain PRK PF00485.13 EME79474.1 - 0.0099 15.4 0.2 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EME79474.1 - 0.013 15.2 0.2 1.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EME79474.1 - 0.014 15.3 0.0 6 6.8 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EME79474.1 - 0.015 14.9 0.2 2.9 7.5 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.1 EME79474.1 - 0.016 15.5 0.0 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME79474.1 - 0.023 14.8 0.0 7.3 6.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EME79474.1 - 0.026 15.0 0.0 4.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 EME79474.1 - 0.035 13.0 0.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EME79474.1 - 0.037 13.8 1.6 2.3 7.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EME79474.1 - 0.052 13.2 2.2 3.2 7.3 0.3 3.0 3 0 0 3 3 3 0 NACHT domain G-alpha PF00503.15 EME79474.1 - 0.053 12.2 0.0 5.6 5.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Viral_helicase1 PF01443.13 EME79474.1 - 0.075 12.5 0.2 17 4.7 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EME79474.1 - 0.077 12.7 0.3 13 5.5 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EME79474.1 - 0.55 9.2 0.0 30 3.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Synaptobrevin PF00957.16 EME79474.1 - 0.61 9.7 2.9 5.7 6.6 0.1 3.4 2 0 0 2 2 2 0 Synaptobrevin Rhodanese PF00581.15 EME79475.1 - 8e-10 39.0 0.0 2.6e-09 37.4 0.0 1.8 1 1 1 2 2 2 1 Rhodanese-like domain Cu-oxidase_2 PF07731.9 EME79476.1 - 1.4e-42 144.4 3.7 4.3e-40 136.4 0.4 2.8 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EME79476.1 - 6.2e-42 142.0 11.1 3.1e-41 139.8 2.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EME79476.1 - 1.2e-32 113.0 0.5 4e-32 111.3 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Glyco_hydro_38 PF01074.17 EME79477.1 - 4.3e-88 295.1 1.6 7.1e-88 294.4 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EME79477.1 - 2.2e-74 250.9 0.0 4.7e-74 249.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EME79477.1 - 1.1e-27 96.1 0.1 2.3e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain RskA PF10099.4 EME79478.1 - 0.059 13.0 0.1 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Cupin_2 PF07883.6 EME79481.1 - 3.2e-09 36.1 0.4 4.3e-09 35.7 0.3 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EME79481.1 - 0.00021 20.9 0.1 0.00026 20.6 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 EME79481.1 - 0.00051 19.5 0.1 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EME79481.1 - 0.0023 17.5 0.5 0.0029 17.2 0.4 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EME79481.1 - 0.016 14.6 0.1 1.3 8.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Acetyltransf_1 PF00583.19 EME79482.1 - 5.6e-16 58.3 0.0 8.4e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME79482.1 - 1.3e-08 34.9 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME79482.1 - 4.1e-08 33.2 0.0 6.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME79482.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EME79482.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EME79482.1 - 0.0017 18.2 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_8 PF13450.1 EME79484.1 - 3.8e-12 46.0 0.5 7.5e-12 45.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME79484.1 - 9.7e-08 31.2 0.5 0.00013 21.0 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EME79484.1 - 1.3e-07 31.0 0.0 2.3e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EME79484.1 - 1e-06 28.9 0.1 1.4e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME79484.1 - 1.5e-06 28.2 0.5 0.00016 21.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME79484.1 - 2.6e-05 22.8 0.5 0.00014 20.4 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EME79484.1 - 9.9e-05 21.3 0.6 0.00017 20.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EME79484.1 - 0.0053 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EME79484.1 - 0.006 15.7 2.4 0.016 14.2 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 EME79484.1 - 0.0077 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.12 EME79484.1 - 0.011 14.7 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EME79484.1 - 0.013 15.9 0.1 0.082 13.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME79484.1 - 0.03 14.0 0.6 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EME79484.1 - 0.098 11.4 0.2 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EME79484.1 - 0.16 11.4 0.2 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_15 PF00723.16 EME79485.1 - 9.2e-100 334.2 0.0 1.1e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EME79485.1 - 2.4e-33 113.5 0.7 5.6e-33 112.4 0.5 1.6 1 0 0 1 1 1 1 Starch binding domain Beta-lactamase PF00144.19 EME79487.1 - 2.3e-43 148.5 0.0 3.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EME79487.1 - 2.5e-08 33.6 0.1 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) FAM176 PF14851.1 EME79488.1 - 2.5 7.7 6.2 2.8 7.6 4.3 1.2 1 0 0 1 1 1 0 FAM176 family 2OG-FeII_Oxy PF03171.15 EME79490.1 - 0.018 15.3 0.0 0.034 14.4 0.0 1.5 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Telomere_reg-2 PF10193.4 EME79492.1 - 3.5e-32 111.0 0.0 2.1e-31 108.5 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.16 EME79493.1 - 8.1e-39 132.5 0.1 1.6e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.5 EME79493.1 - 1.9e-26 91.6 0.2 3e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EME79493.1 - 1.4e-25 88.6 0.4 3.8e-25 87.2 0.2 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EME79493.1 - 2e-15 55.8 3.0 9.8e-15 53.6 1.7 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EME79493.1 - 0.00053 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EME79493.1 - 0.0094 16.0 0.1 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.3 EME79493.1 - 3.2 7.7 7.0 0.29 11.0 1.5 1.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein HATPase_c PF02518.21 EME79495.1 - 3.7e-30 103.9 0.4 7.7e-30 102.8 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME79495.1 - 1.9e-21 75.8 0.0 9.2e-21 73.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EME79495.1 - 8.2e-21 74.3 0.0 8.3e-09 35.7 0.0 4.6 4 0 0 4 4 4 3 PAS domain Response_reg PF00072.19 EME79495.1 - 1.7e-20 73.0 0.1 7.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 EME79495.1 - 9.8e-16 57.6 0.1 1.7e-14 53.6 0.2 2.8 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.5 EME79495.1 - 6.5e-15 55.1 0.1 0.00067 19.6 0.0 5.0 4 1 0 4 4 4 3 PAS fold PAS PF00989.19 EME79495.1 - 5.1e-10 39.1 0.0 0.011 15.4 0.0 4.1 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.1 EME79495.1 - 0.0014 18.4 0.3 0.019 14.7 0.0 3.1 3 1 1 4 4 4 1 PAS domain HATPase_c_3 PF13589.1 EME79495.1 - 0.0031 17.1 0.0 0.0083 15.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4126 PF13548.1 EME79495.1 - 0.15 11.4 1.0 0.28 10.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) O-FucT PF10250.4 EME79496.1 - 1.4e-05 24.3 0.3 0.0026 16.9 0.2 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF605 PF04652.11 EME79497.1 - 2.3e-90 303.7 3.0 2.6e-90 303.5 2.1 1.0 1 0 0 1 1 1 1 Vta1 like Thioredoxin PF00085.15 EME79498.1 - 3.7e-33 113.3 0.2 1.2e-25 89.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EME79498.1 - 2.6e-13 50.1 0.5 5.3e-07 29.8 0.1 2.9 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EME79498.1 - 1.4e-11 44.5 0.0 1.9e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EME79498.1 - 1.6e-06 28.0 0.2 0.074 13.1 0.0 4.4 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EME79498.1 - 6.1e-06 26.1 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EME79498.1 - 0.00011 21.9 0.0 0.00085 19.0 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family ERp29_N PF07912.8 EME79498.1 - 0.00083 19.2 0.0 0.0088 15.9 0.0 2.2 2 0 0 2 2 2 1 ERp29, N-terminal domain TraF PF13728.1 EME79498.1 - 0.0027 17.2 7.9 0.0093 15.4 0.0 3.3 4 0 0 4 4 4 1 F plasmid transfer operon protein Neisseria_TspB PF05616.8 EME79498.1 - 0.0081 14.5 2.3 0.011 14.1 1.6 1.2 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein Thioredoxin_3 PF13192.1 EME79498.1 - 0.011 15.4 0.1 0.093 12.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain DSBA PF01323.15 EME79498.1 - 0.03 13.8 0.1 0.49 9.9 0.0 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3294 PF07957.6 EME79498.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Glutaredoxin PF00462.19 EME79498.1 - 0.32 11.0 1.5 10 6.2 0.5 2.9 2 1 0 2 2 2 0 Glutaredoxin PhoD PF09423.5 EME79499.1 - 2.3e-08 33.0 0.1 1.1e-07 30.7 0.1 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.17 EME79500.1 - 3.8e-54 183.7 0.4 5.5e-54 183.2 0.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EME79500.1 - 2.7e-28 97.5 0.9 5.5e-28 96.5 0.6 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Rad4 PF03835.10 EME79501.1 - 4.3e-14 52.1 2.4 6.1e-14 51.6 0.7 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EME79501.1 - 5.5e-11 42.6 1.5 1.1e-10 41.6 0.6 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily MRP-L47 PF06984.8 EME79503.1 - 9.2e-23 79.9 0.7 1.4e-22 79.3 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) ATG16 PF08614.6 EME79505.1 - 0.00072 19.4 0.5 0.00072 19.4 0.4 2.7 2 2 1 3 3 3 1 Autophagy protein 16 (ATG16) DUF3984 PF13136.1 EME79505.1 - 0.7 9.0 7.5 0.056 12.6 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) DUF2721 PF11026.3 EME79505.1 - 4.5 6.9 5.8 3.7 7.2 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) ABC2_membrane PF01061.19 EME79510.1 - 3.4e-83 277.9 48.9 7.4e-45 152.6 9.9 2.9 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EME79510.1 - 1e-37 129.4 0.0 1.3e-18 67.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EME79510.1 - 1.4e-22 79.2 0.7 6.5e-20 70.7 0.0 2.6 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 EME79510.1 - 1.3e-10 41.1 0.1 3.8e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EME79510.1 - 5.1e-07 29.0 31.6 0.00088 18.3 6.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EME79510.1 - 1.2e-06 28.0 0.1 0.0045 16.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME79510.1 - 1.3e-05 25.2 0.1 0.039 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME79510.1 - 0.00065 19.7 0.7 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EME79510.1 - 0.00072 18.7 0.1 0.0057 15.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME79510.1 - 0.0023 18.7 0.0 1.1 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EME79510.1 - 0.0024 17.3 1.2 0.35 10.2 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EME79510.1 - 0.0029 17.1 1.0 1.3 8.5 0.2 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EME79510.1 - 0.0076 15.7 0.6 0.082 12.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EME79510.1 - 0.0085 16.0 0.0 0.93 9.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EME79510.1 - 0.012 15.3 0.4 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EME79510.1 - 0.016 15.1 2.2 0.34 10.8 0.5 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME79510.1 - 0.019 14.6 0.6 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EME79510.1 - 0.02 15.1 0.1 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EME79510.1 - 0.027 14.9 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EME79510.1 - 0.031 14.4 0.0 8.2 6.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EME79510.1 - 0.046 13.6 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME79510.1 - 0.054 13.1 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EME79510.1 - 0.18 11.4 1.1 5.7 6.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Ran_BP1 PF00638.13 EME79512.1 - 8.6e-13 48.4 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain F-box PF00646.28 EME79513.1 - 0.0081 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME79513.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like MBOAT_2 PF13813.1 EME79514.1 - 2e-17 63.0 5.9 2e-17 63.0 4.1 2.2 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Peptidase_S24 PF00717.18 EME79515.1 - 5.7e-05 22.6 0.0 9.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF1295 PF06966.7 EME79516.1 - 1.9e-36 125.5 0.6 1.7e-18 66.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) ICMT PF04140.9 EME79516.1 - 0.00018 21.6 1.7 0.00025 21.1 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EME79516.1 - 0.11 12.2 3.2 0.2 11.3 0.0 2.8 3 2 1 4 4 4 0 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EME79516.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.9 3 1 1 4 4 4 0 Phospholipid methyltransferase RmlD_sub_bind PF04321.12 EME79517.1 - 4.6e-16 58.5 0.0 9.3e-16 57.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EME79517.1 - 8.2e-13 48.3 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EME79517.1 - 0.028 14.3 0.1 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase TPT PF03151.11 EME79518.1 - 2.7e-15 56.3 8.9 2.7e-15 56.3 6.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME79518.1 - 1e-05 25.5 25.3 0.0001 22.3 5.4 3.0 2 1 1 3 3 3 3 EamA-like transporter family TRI9 PF08195.6 EME79518.1 - 0.021 14.4 0.2 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 TRI9 protein EmrE PF13536.1 EME79518.1 - 0.028 14.6 22.0 0.05 13.7 2.4 2.9 2 1 1 3 3 3 0 Multidrug resistance efflux transporter YxiJ PF14176.1 EME79518.1 - 0.06 13.4 0.1 4.3 7.5 0.0 2.3 2 0 0 2 2 2 0 YxiJ-like protein Epimerase PF01370.16 EME79519.1 - 6e-57 192.7 0.2 7.5e-57 192.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME79519.1 - 1.7e-21 76.3 0.0 1.6e-20 73.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EME79519.1 - 2.7e-18 65.7 0.2 6.8e-17 61.2 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EME79519.1 - 7.6e-18 64.1 0.0 1e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME79519.1 - 1.6e-17 63.3 0.0 2.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME79519.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EME79519.1 - 0.036 13.9 0.2 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase zf-C2H2 PF00096.21 EME79520.1 - 5.1e-11 42.2 11.3 4.2e-06 26.7 3.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME79520.1 - 8.6e-11 41.5 19.7 2.5e-06 27.4 0.2 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME79520.1 - 3e-08 33.4 8.4 4.6e-05 23.4 1.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EME79520.1 - 9.6e-06 25.6 1.5 9.6e-06 25.6 1.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME79520.1 - 1.8e-05 24.7 5.9 6.9e-05 22.8 1.9 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EME79520.1 - 0.0002 21.1 7.0 0.0031 17.3 1.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EME79520.1 - 0.084 12.5 4.1 3.3 7.4 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PAP2 PF01569.16 EME79520.1 - 0.21 11.2 2.9 0.12 12.0 0.7 1.5 2 0 0 2 2 2 0 PAP2 superfamily zf-C2H2_2 PF12756.2 EME79520.1 - 0.31 11.1 5.2 0.12 12.5 1.3 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EME79520.1 - 1 9.1 8.1 14 5.5 5.6 2.3 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 EME79520.1 - 3.8 7.9 7.4 34 4.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain HET PF06985.6 EME79521.1 - 1.3e-28 99.9 0.0 1.7e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_28 PF02636.12 EME79522.1 - 2.1e-37 128.8 0.0 3.2e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EME79522.1 - 0.034 13.0 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PALP PF00291.20 EME79523.1 - 1.1e-60 205.4 0.5 1.3e-60 205.1 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 EME79524.1 - 3.3e-53 180.6 22.0 3.3e-53 180.6 15.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME79524.1 - 3.6e-11 42.3 30.7 1.5e-10 40.2 21.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Scm3 PF10384.4 EME79525.1 - 2e-18 65.5 0.3 4.5e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EME79525.1 - 1.5e-16 60.2 0.4 3.7e-07 30.1 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME79525.1 - 1.9e-08 34.2 0.3 0.0038 17.2 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain GATA PF00320.22 EME79525.1 - 5.4e-05 22.4 4.8 0.00011 21.4 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger Sigma70_r4_2 PF08281.7 EME79525.1 - 0.025 14.0 0.0 0.73 9.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 CENP-B_dimeris PF09026.5 EME79525.1 - 0.16 12.2 10.3 0.65 10.2 7.1 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain APG6 PF04111.7 EME79526.1 - 5.8e-123 409.9 0.0 7.1e-123 409.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EME79526.1 - 0.09 10.6 8.0 0.13 10.1 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 EME79526.1 - 0.22 10.7 10.4 0.44 9.7 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 EME79526.1 - 0.63 8.3 3.9 0.99 7.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HrpA_pilin PF09589.5 EME79526.1 - 0.68 10.3 4.5 1.9 8.9 3.1 1.7 1 1 0 1 1 1 0 HrpA pilus formation protein GAS PF13851.1 EME79526.1 - 1.1 8.4 16.7 0.49 9.5 7.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4337 PF14235.1 EME79526.1 - 1.3 8.8 9.4 3 7.6 6.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Mnd1 PF03962.10 EME79526.1 - 2 8.0 15.2 10 5.7 10.5 1.9 1 1 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 EME79526.1 - 3.1 8.1 6.5 3.5 8.0 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EME79526.1 - 3.8 7.8 11.8 1.5 9.1 6.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DDRGK PF09756.4 EME79526.1 - 9.5 5.5 14.6 14 4.9 10.1 1.2 1 0 0 1 1 1 0 DDRGK domain adh_short PF00106.20 EME79527.1 - 1e-17 64.5 0.2 1.7e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EME79527.1 - 4.4e-05 23.0 0.1 0.0001 21.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME79527.1 - 0.00014 21.5 0.2 0.00041 20.0 0.1 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EME79527.1 - 0.00022 21.0 0.0 0.00055 19.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peripla_BP_3 PF13377.1 EME79527.1 - 0.0046 16.9 0.1 0.094 12.7 0.0 2.7 3 1 0 3 3 3 1 Periplasmic binding protein-like domain Saccharop_dh PF03435.13 EME79527.1 - 0.011 14.7 0.2 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EME79527.1 - 0.034 14.1 0.2 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding Tn7_TnsC_Int PF11426.3 EME79527.1 - 0.045 13.4 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC Sel1 PF08238.7 EME79528.1 - 4.9e-12 46.0 12.3 2.5e-05 24.7 0.3 4.1 4 0 0 4 4 4 3 Sel1 repeat zf-DHHC PF01529.15 EME79529.1 - 9.1e-37 126.1 8.9 9.1e-37 126.1 6.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EME79529.1 - 3.6e-35 120.1 1.1 1.9e-15 56.9 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EME79529.1 - 1.1e-31 107.0 9.3 2.5e-09 36.4 0.5 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EME79529.1 - 3e-22 78.5 5.1 2.4e-06 27.9 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME79529.1 - 2.4e-20 70.5 3.0 1.4e-06 27.9 0.2 6.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EME79529.1 - 1e-18 66.9 13.0 1e-08 35.1 0.0 5.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) DZR PF12773.2 EME79529.1 - 3.6 7.4 8.5 6.4 6.6 5.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon PGI PF00342.14 EME79532.1 - 5.8e-218 724.1 0.8 6.8e-218 723.9 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 EME79533.1 - 8e-72 241.5 0.0 1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79533.1 - 1.6e-33 115.8 0.0 2.4e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EME79533.1 - 1.7e-10 41.2 2.2 3.1e-10 40.4 0.2 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EME79533.1 - 0.00034 19.6 0.0 0.0007 18.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like ZZ PF00569.12 EME79534.1 - 1.1e-11 44.1 4.8 2.2e-11 43.1 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EME79534.1 - 3.6e-11 43.0 0.0 1.1e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EME79534.1 - 4.2e-06 26.7 0.0 2e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4239 PF14023.1 EME79534.1 - 0.27 10.5 1.2 0.45 9.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) NuA4 PF09340.5 EME79535.1 - 3.4e-24 84.2 0.0 5.4e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF1087 PF06465.8 EME79535.1 - 0.045 13.6 0.5 0.085 12.7 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) CorA PF01544.13 EME79536.1 - 0.00074 18.6 5.8 0.0015 17.6 4.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PgaD PF13994.1 EME79536.1 - 0.047 13.1 0.1 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 PgaD-like protein AA_permease_2 PF13520.1 EME79537.1 - 5.1e-13 48.3 12.9 1.6e-12 46.6 7.5 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EME79537.1 - 2e-05 23.1 1.1 2e-05 23.1 0.8 2.8 3 0 0 3 3 3 1 Amino acid permease TctB PF07331.6 EME79537.1 - 4.9 6.8 15.3 6.1 6.5 0.3 2.7 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Pkinase PF00069.20 EME79538.1 - 7.8e-17 61.2 0.0 1.4e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79538.1 - 0.057 12.4 0.0 0.21 10.5 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.6 EME79538.1 - 0.22 10.1 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Abhydrolase_6 PF12697.2 EME79539.1 - 3.3e-36 125.2 0.8 3.9e-36 125.0 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME79539.1 - 4e-20 72.3 0.1 3.1e-16 59.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME79539.1 - 2.2e-16 59.9 1.8 1.2e-15 57.5 1.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EME79539.1 - 2e-06 26.4 0.0 0.0008 17.9 0.0 2.2 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EME79539.1 - 0.00028 20.6 0.1 0.00061 19.5 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EME79539.1 - 0.0085 15.9 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 1 TAP-like protein Esterase PF00756.15 EME79539.1 - 0.018 14.5 0.1 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EME79539.1 - 0.041 13.1 0.2 0.22 10.7 0.2 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF4550 PF15084.1 EME79542.1 - 0.12 12.4 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) Tyrosinase PF00264.15 EME79543.1 - 2.5e-32 112.8 0.7 3.2e-32 112.4 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Thioredoxin_4 PF13462.1 EME79545.1 - 3.9e-08 33.4 0.1 1.3e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EME79545.1 - 0.0032 17.0 3.6 0.021 14.3 0.5 2.4 1 1 1 2 2 2 1 DSBA-like thioredoxin domain DUF3658 PF12395.3 EME79545.1 - 0.097 12.2 0.0 1.6 8.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function Sigma70_ECF PF07638.6 EME79545.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor Fungal_trans_2 PF11951.3 EME79547.1 - 2.9e-17 62.3 0.4 1.1e-11 43.9 1.4 2.9 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79547.1 - 1.8e-07 30.9 12.2 3.3e-07 30.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME79547.1 - 0.0019 17.1 0.6 0.0067 15.3 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Neisseria_TspB PF05616.8 EME79548.1 - 0.11 10.8 10.4 0.15 10.3 7.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF629 PF04780.7 EME79548.1 - 1.9 6.9 5.0 0.71 8.3 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF629) Fe-ADH PF00465.14 EME79549.1 - 4.6e-64 216.3 0.2 6e-64 215.9 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME79549.1 - 2.1e-11 43.6 0.0 3.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Amidohydro_2 PF04909.9 EME79551.1 - 1.7e-27 96.6 0.0 2.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EME79552.1 - 1.5e-16 60.9 0.5 9.4e-16 58.3 0.4 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EME79552.1 - 3.1e-16 60.2 7.6 8.1e-15 55.5 5.3 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME79552.1 - 5.6e-13 48.8 4.0 3.1e-09 36.5 0.6 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EME79552.1 - 2.9e-11 43.0 0.0 8.9e-11 41.4 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase DUF3197 PF11432.3 EME79552.1 - 0.084 12.8 0.1 0.29 11.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3197) MgtE_N PF03448.12 EME79552.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain Fungal_trans PF04082.13 EME79554.1 - 3.9e-31 107.8 0.0 1.2e-30 106.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79554.1 - 8e-08 32.0 8.4 1.4e-07 31.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EME79555.1 - 1.3e-05 25.5 0.2 9.4e-05 22.7 0.2 2.0 1 1 0 1 1 1 1 SET domain TGT PF01702.13 EME79556.1 - 3.1e-86 288.5 0.0 4.1e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase zf-GRF PF06839.7 EME79557.1 - 5.9e-06 26.0 5.8 0.02 14.8 0.4 2.7 2 0 0 2 2 2 2 GRF zinc finger GVQW PF13900.1 EME79557.1 - 0.14 12.1 0.2 0.14 12.1 0.1 2.3 3 0 0 3 3 3 0 Putative binding domain zf-AN1 PF01428.11 EME79558.1 - 1.2e-23 82.6 21.1 1.1e-12 47.6 4.7 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EME79558.1 - 0.00057 19.7 15.7 0.021 14.6 2.8 2.4 2 0 0 2 2 2 2 IBR domain CpXC PF14353.1 EME79558.1 - 0.22 11.5 2.5 0.47 10.4 0.1 2.3 2 0 0 2 2 2 0 CpXC protein Transp_Tc5_C PF04236.10 EME79558.1 - 0.25 11.5 13.4 0.44 10.8 1.6 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain SspB PF04386.8 EME79559.1 - 0.0033 17.0 2.3 0.21 11.2 1.2 2.4 2 1 0 2 2 2 2 Stringent starvation protein B Ctr PF04145.10 EME79560.1 - 1.7e-45 154.5 1.1 2.2e-45 154.2 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.1 EME79560.1 - 0.084 12.4 2.3 4.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Putative sensor DUF1673 PF07895.6 EME79560.1 - 0.086 12.3 1.0 0.83 9.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4407 PF14362.1 EME79560.1 - 0.47 9.3 1.8 0.95 8.3 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1049 PF06305.6 EME79560.1 - 5.4 6.5 7.1 30 4.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Oxidored_q3 PF00499.15 EME79560.1 - 6.4 6.5 13.6 0.29 10.8 3.6 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ADH_zinc_N PF00107.21 EME79562.1 - 1.5e-11 43.9 1.0 2.4e-11 43.3 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME79562.1 - 2.6e-11 43.2 0.0 6e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 EME79562.1 - 0.038 13.1 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) adh_short PF00106.20 EME79562.1 - 0.062 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EME79562.1 - 0.069 13.1 1.4 0.1 12.6 1.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding ADH_zinc_N_2 PF13602.1 EME79562.1 - 0.075 13.9 0.0 0.13 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PsbL PF02419.12 EME79563.1 - 0.29 10.5 1.6 0.57 9.6 1.1 1.5 1 0 0 1 1 1 0 PsbL protein Acetyltransf_1 PF00583.19 EME79565.1 - 2.7e-12 46.5 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME79565.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME79565.1 - 0.00012 21.9 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME79565.1 - 0.00055 19.6 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EME79565.1 - 0.0016 18.3 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME79565.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME79565.1 - 0.048 13.5 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UBA PF00627.26 EME79567.1 - 2.1e-08 33.7 0.1 4.9e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 EME79567.1 - 7.7e-07 28.4 0.0 2.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family UBA_4 PF14555.1 EME79567.1 - 0.0029 17.0 0.3 0.0056 16.1 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain YukD PF08817.5 EME79567.1 - 0.024 15.1 0.1 0.077 13.5 0.0 1.9 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD RuvA_C PF07499.8 EME79567.1 - 0.042 14.0 0.2 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 RuvA, C-terminal domain UN_NPL4 PF11543.3 EME79567.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PRO8NT PF08082.6 EME79567.1 - 0.33 10.5 1.8 0.54 9.8 1.3 1.2 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain IBR PF01485.16 EME79568.1 - 0.0013 18.5 7.9 0.0013 18.5 5.5 4.3 4 1 1 5 5 5 2 IBR domain PSK PF06404.7 EME79569.1 - 4.5e-05 24.1 17.3 0.067 13.9 0.3 4.0 3 1 1 4 4 4 3 Phytosulfokine precursor protein (PSK) Arylsulfotran_2 PF14269.1 EME79570.1 - 1.2e-47 162.5 0.0 1.8e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME79570.1 - 6.8e-12 44.6 0.4 9.4e-11 40.8 0.3 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) WW PF00397.21 EME79571.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 WW domain Metallothio_11 PF02066.10 EME79571.1 - 5.5 6.9 12.3 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Metallothionein family 11 OPA3 PF07047.7 EME79572.1 - 1e-34 119.2 0.0 1.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) bZIP_2 PF07716.10 EME79572.1 - 0.01 15.6 1.6 0.021 14.6 1.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper DUF1049 PF06305.6 EME79572.1 - 0.014 14.8 0.1 0.036 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 EME79573.1 - 6.8e-62 208.9 0.0 1.3e-61 208.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79573.1 - 7.7e-42 143.1 0.0 1.3e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME79573.1 - 1.4e-10 40.6 0.0 2.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EME79573.1 - 2.1e-09 37.2 0.0 0.00023 21.0 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EME79573.1 - 0.0032 16.5 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CMD PF02627.15 EME79574.1 - 1.6e-11 43.8 0.0 2.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Chordopox_A15 PF05846.7 EME79576.1 - 0.013 15.5 0.8 12 6.0 0.0 3.6 2 2 2 4 4 4 0 Chordopoxvirus A15 protein Chromadorea_ALT PF05535.7 EME79576.1 - 0.014 15.4 37.8 0.54 10.3 1.2 5.4 1 1 4 5 5 5 0 Chromadorea ALT protein Flocculin PF00624.13 EME79576.1 - 0.3 10.9 8.3 47 3.9 0.0 5.5 7 0 0 7 7 7 0 Flocculin repeat 7kD_coat PF02495.12 EME79576.1 - 5.5 6.5 7.8 6.7 6.2 0.1 3.5 3 0 0 3 3 3 0 7kD viral coat protein Lamprin PF06403.6 EME79577.1 - 1.2 8.8 4.3 1.7 8.3 3.0 1.4 1 1 0 1 1 1 0 Lamprin SAD_SRA PF02182.12 EME79578.1 - 3.1e-12 46.0 0.0 2.2e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 SAD/SRA domain Amidase PF01425.16 EME79579.1 - 3.2e-91 306.4 0.0 4.2e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Peptidase_S9 PF00326.16 EME79580.1 - 2.6e-47 160.8 2.0 3.8e-30 104.7 0.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Pkinase PF00069.20 EME79580.1 - 2.1e-32 112.2 0.0 5.5e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Abhydrolase_6 PF12697.2 EME79580.1 - 6.6e-10 39.2 1.0 1.4e-09 38.1 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase_Tyr PF07714.12 EME79580.1 - 2e-09 36.9 0.0 1.4e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_5 PF12695.2 EME79580.1 - 2.5e-09 37.0 0.1 9.4e-09 35.1 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.18 EME79580.1 - 8.9e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Esterase PF00756.15 EME79580.1 - 0.00021 20.7 1.2 0.00021 20.7 0.8 1.9 2 0 0 2 2 2 1 Putative esterase COesterase PF00135.23 EME79580.1 - 0.0022 16.7 1.1 0.0034 16.1 0.7 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2920 PF11144.3 EME79580.1 - 0.09 11.7 0.0 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Glyco_hydro_2_C PF02836.12 EME79581.1 - 1.4e-105 352.4 0.0 1.9e-105 352.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EME79581.1 - 9.7e-59 198.6 0.0 1.4e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EME79581.1 - 5.2e-49 166.0 0.0 1e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EME79581.1 - 2.4e-14 53.7 0.0 8.1e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EME79581.1 - 0.053 13.7 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Sugar_tr PF00083.19 EME79582.1 - 3.2e-92 309.4 21.0 3.8e-92 309.2 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79582.1 - 1.8e-32 112.4 20.0 2.7e-32 111.8 13.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME79582.1 - 0.0017 16.6 0.6 0.0032 15.7 0.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EME79583.1 - 3.3e-10 39.2 1.7 6.6e-10 38.3 1.1 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79583.1 - 8.8e-09 35.1 5.9 2e-08 33.9 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EME79584.1 - 2.8e-68 230.5 17.5 3.4e-68 230.2 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79584.1 - 4.2e-22 78.3 20.4 4.2e-22 78.3 14.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME79584.1 - 5e-05 21.8 2.9 5e-05 21.8 2.0 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EME79584.1 - 0.00093 17.5 0.6 0.0014 16.9 0.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 EME79585.1 - 5.5e-23 82.0 1.1 7.2e-23 81.6 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME79585.1 - 5.1e-07 29.5 0.1 1.6e-06 27.9 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME79585.1 - 6.5e-06 25.8 0.0 1.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2237 PF09996.4 EME79587.1 - 1.6e-30 104.9 0.2 3.6e-30 103.8 0.2 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF846 PF05832.7 EME79590.1 - 1.3e-52 177.2 6.0 1.5e-52 177.0 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.1 EME79590.1 - 0.023 15.1 1.5 0.032 14.6 0.1 1.8 2 0 0 2 2 2 0 Transmembrane family 220, helix HeLo PF14479.1 EME79591.1 - 1.3e-17 64.2 0.7 2.1e-17 63.5 0.5 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF4279 PF14106.1 EME79591.1 - 0.094 12.5 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) NOG1 PF06858.9 EME79592.1 - 9.1e-27 92.7 0.4 2.1e-26 91.5 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EME79592.1 - 3.3e-26 90.7 1.8 9.3e-26 89.2 1.3 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EME79592.1 - 3.1e-14 52.9 0.0 6.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME79592.1 - 9.8e-09 34.6 0.1 2.1e-08 33.6 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EME79592.1 - 0.00012 21.3 0.2 0.00022 20.4 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME79592.1 - 0.00028 21.3 0.0 0.0056 17.1 0.0 2.4 1 1 0 2 2 2 1 Miro-like protein Lip_prot_lig_C PF10437.4 EME79592.1 - 0.047 13.3 0.1 14 5.4 0.0 3.3 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus Dynamin_N PF00350.18 EME79592.1 - 0.05 13.4 2.4 5.3 6.8 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_17 PF13207.1 EME79592.1 - 0.097 13.4 0.5 2.3 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Glyco_hydro_16 PF00722.16 EME79594.1 - 1.3e-08 34.3 0.4 4.8e-08 32.4 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EME79594.1 - 0.0033 15.6 0.5 0.0073 14.5 0.3 1.6 1 1 1 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) Polysacc_lyase PF14099.1 EME79594.1 - 0.013 15.1 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide lyase Csm1 PF12539.3 EME79596.1 - 3.6e-26 91.4 0.2 1e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 IncA PF04156.9 EME79596.1 - 0.00042 19.9 21.3 0.0093 15.5 8.4 2.5 1 1 1 2 2 2 2 IncA protein Filament PF00038.16 EME79596.1 - 0.0022 17.5 15.4 0.0022 17.5 10.7 2.6 2 1 0 2 2 2 1 Intermediate filament protein Takusan PF04822.8 EME79596.1 - 0.046 13.4 9.7 2.9 7.6 2.2 3.5 3 0 0 3 3 3 0 Takusan Alpha-2-MRAP_C PF06401.6 EME79596.1 - 0.054 13.3 10.1 0.11 12.3 7.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain V_ATPase_I PF01496.14 EME79596.1 - 2 6.1 12.2 3.7 5.2 8.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EME79596.1 - 2.5 7.8 23.3 3.5 7.3 5.4 3.9 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 EME79596.1 - 8.9 4.8 22.7 1.2e+02 1.1 15.8 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Sugar_tr PF00083.19 EME79597.1 - 2.8e-73 247.0 26.8 3.2e-73 246.8 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79597.1 - 1.3e-17 63.5 43.0 6e-12 44.9 10.3 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME79597.1 - 0.00014 20.4 6.2 0.00014 20.4 4.3 3.0 2 2 0 3 3 3 2 MFS/sugar transport protein LexA_DNA_bind PF01726.11 EME79598.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain DUF4254 PF14063.1 EME79598.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) TMF_TATA_bd PF12325.3 EME79598.1 - 0.15 11.7 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fungal_trans PF04082.13 EME79600.1 - 3.9e-58 196.3 0.1 5.6e-58 195.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EME79600.1 - 7.3e-06 26.0 10.6 2.4e-05 24.4 0.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME79600.1 - 1.5e-05 25.0 8.9 0.0027 17.8 2.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME79600.1 - 2.9e-05 24.0 10.8 0.00024 21.1 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger HD_3 PF13023.1 EME79601.1 - 2.4e-47 160.7 0.1 3.2e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 EME79601.1 - 0.00098 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HAUS6_N PF14661.1 EME79602.1 - 3.5e-40 137.9 0.7 9.1e-40 136.5 0.5 1.7 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus AMP-binding PF00501.23 EME79603.1 - 2.6e-78 263.2 0.0 3.3e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME79603.1 - 4e-13 50.1 0.0 8.9e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain URO-D PF01208.12 EME79604.1 - 2.4e-122 408.1 0.0 2.7e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.17 EME79605.1 - 2.2e-22 78.6 0.1 2.9e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EME79605.1 - 0.00082 19.0 0.0 0.0017 18.0 0.0 1.6 2 0 0 2 2 2 1 Xanthomonas XOO_2897-like deaminase Bd3614-deam PF14439.1 EME79605.1 - 0.014 15.2 2.5 0.14 11.9 0.5 2.1 1 1 1 2 2 2 0 Bd3614-like deaminase PAH PF02671.16 EME79606.1 - 2.9e-43 145.2 0.7 1.1e-16 60.1 0.3 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EME79606.1 - 1.7e-37 127.1 0.0 6.9e-37 125.2 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor Pyr_redox_2 PF07992.9 EME79607.1 - 9.7e-30 103.9 0.0 1.6e-29 103.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME79607.1 - 2.7e-15 56.5 0.1 4e-13 49.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME79607.1 - 1e-09 38.7 0.4 1.6e-05 25.0 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME79607.1 - 1.2e-06 27.8 0.1 0.00051 19.1 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EME79607.1 - 7.6e-06 25.0 0.3 0.0062 15.4 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EME79607.1 - 3.8e-05 22.9 0.4 0.00014 21.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EME79607.1 - 0.00017 20.5 0.3 0.21 10.4 0.2 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EME79607.1 - 0.00022 20.2 0.1 0.02 13.8 0.0 2.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EME79607.1 - 0.003 16.0 0.1 0.055 11.9 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EME79607.1 - 0.0097 15.9 0.1 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EME79607.1 - 0.021 15.1 0.3 0.23 11.7 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EME79607.1 - 0.031 13.1 8.8 0.048 12.4 1.0 3.1 2 1 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 EME79607.1 - 0.057 13.5 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EME79607.1 - 0.066 11.8 0.1 1.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Pro_isomerase PF00160.16 EME79608.1 - 1.3e-49 168.4 0.2 1.4e-49 168.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aconitase PF00330.15 EME79609.1 - 1.6e-179 597.2 0.0 1.9e-179 597.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME79609.1 - 4.3e-45 153.0 0.0 1e-44 151.8 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Peptidase_M28 PF04389.12 EME79610.1 - 1e-27 97.0 0.3 1.8e-27 96.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EME79610.1 - 3.2e-07 30.0 0.1 4.5e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EME79610.1 - 0.0086 14.8 0.1 1.7 7.3 0.0 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase SecE PF00584.15 EME79611.1 - 0.37 10.3 1.6 0.69 9.5 1.1 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex PAN_1 PF00024.21 EME79612.1 - 0.0058 16.3 2.7 0.0058 16.3 1.8 1.8 3 0 0 3 3 3 1 PAN domain PAN_3 PF08277.7 EME79612.1 - 0.0086 15.6 2.5 0.018 14.6 1.7 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_4 PF14295.1 EME79612.1 - 0.029 14.0 5.6 0.057 13.1 3.9 1.5 1 0 0 1 1 1 0 PAN domain Na_Ca_ex PF01699.19 EME79613.1 - 6.2e-26 90.6 20.7 1.8e-14 53.5 5.4 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF443 PF04276.7 EME79613.1 - 0.019 14.4 0.2 0.019 14.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF443) DUF3169 PF11368.3 EME79613.1 - 0.034 13.3 0.1 0.034 13.3 0.1 2.8 3 1 2 5 5 5 0 Protein of unknown function (DUF3169) DUF872 PF05915.7 EME79613.1 - 0.041 13.7 1.9 0.13 12.1 0.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) UPF0016 PF01169.14 EME79613.1 - 0.2 11.7 0.1 0.2 11.7 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized protein family UPF0016 zf-CSL PF05207.8 EME79614.1 - 0.25 10.8 1.0 0.35 10.4 0.1 1.9 2 1 0 2 2 2 0 CSL zinc finger DUF3446 PF11928.3 EME79615.1 - 0.039 14.1 5.1 0.07 13.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) SSP160 PF06933.6 EME79615.1 - 1.7 6.5 12.6 2.2 6.1 8.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 KRE9 PF05390.6 EME79616.1 - 8.7e-12 45.3 8.7 8.7e-12 45.3 6.0 1.9 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EME79616.1 - 1.1e-10 41.8 1.1 1.1e-10 41.8 0.7 2.3 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF448 PF04296.8 EME79617.1 - 0.019 14.5 0.2 0.051 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF448) GRASP55_65 PF04495.9 EME79617.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain zf-GRF PF06839.7 EME79617.1 - 0.057 13.3 8.5 0.34 10.8 0.4 2.4 2 0 0 2 2 2 0 GRF zinc finger zf-UBR PF02207.15 EME79617.1 - 0.32 10.7 3.3 1.3 8.7 2.3 1.9 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Zn-ribbon_8 PF09723.5 EME79617.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain WD40 PF00400.27 EME79618.1 - 0.0033 17.2 3.5 0.029 14.2 0.4 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat DnaJ PF00226.26 EME79620.1 - 6.2e-27 93.1 3.3 1.4e-26 92.0 2.3 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME79620.1 - 1e-23 83.0 0.2 3.2e-20 71.8 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME79620.1 - 6.9e-14 51.6 21.8 1.3e-13 50.7 15.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EME79620.1 - 0.13 11.9 11.5 0.26 10.9 2.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EME79620.1 - 4.3 7.1 7.3 2.7 7.8 1.4 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 EME79620.1 - 7.9 6.3 5.5 7.8 6.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) FR47 PF08445.5 EME79621.1 - 0.0015 18.2 0.0 0.0084 15.8 0.0 2.2 2 1 0 2 2 2 1 FR47-like protein GET2 PF08690.5 EME79622.1 - 2.8 7.1 5.9 4 6.5 4.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Ribosomal_L10 PF00466.15 EME79624.1 - 2.3e-24 85.2 0.1 4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EME79624.1 - 3.9e-21 75.2 5.0 3.9e-21 75.2 3.4 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF726 PF05277.7 EME79626.1 - 6.5e-122 406.7 2.1 8.4e-122 406.3 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EME79626.1 - 0.0075 16.0 0.2 0.095 12.4 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family Endonuc_Holl PF10107.4 EME79626.1 - 4.8 6.8 7.2 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Fcf1 PF04900.7 EME79627.1 - 2.4e-27 94.9 1.1 3.8e-27 94.3 0.1 1.9 2 0 0 2 2 2 1 Fcf1 CDC45 PF02724.9 EME79627.1 - 2.2 6.2 10.8 3.2 5.6 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TMEM237 PF15383.1 EME79627.1 - 5.7 5.9 5.7 8.9 5.3 3.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 NAD_binding_4 PF07993.7 EME79628.1 - 1.9e-38 131.8 0.0 3e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EME79628.1 - 2.1e-33 115.3 0.0 3.7e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EME79628.1 - 2.9e-14 53.1 0.0 5.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME79628.1 - 1.4e-07 30.4 0.0 3.7e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EME79628.1 - 3.2e-05 24.0 0.1 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.5 EME79628.1 - 4.3e-05 23.2 0.1 0.00012 21.8 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME79628.1 - 0.00049 20.1 0.0 0.0027 17.7 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EME79628.1 - 0.0029 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EME79628.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NmrA PF05368.8 EME79629.1 - 4.9e-24 84.8 0.0 5.9e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EME79629.1 - 5.2e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EME79629.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME79629.1 - 0.0029 17.0 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 EME79629.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.5 EME79629.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.13 EME79629.1 - 0.021 14.8 0.1 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 EME79629.1 - 0.075 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LigB PF02900.13 EME79630.1 - 5e-50 169.9 0.1 6.3e-50 169.6 0.1 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Transp_cyt_pur PF02133.10 EME79631.1 - 1.5e-87 293.9 37.9 2e-87 293.5 26.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.16 EME79632.1 - 1.2e-95 321.0 0.0 1.3e-95 320.8 0.0 1.0 1 0 0 1 1 1 1 Amidase SNF PF00209.13 EME79633.1 - 2.5e-73 247.3 36.5 1.8e-45 155.3 14.5 3.0 3 0 0 3 3 3 3 Sodium:neurotransmitter symporter family DUF1776 PF08643.5 EME79634.1 - 1.7e-60 204.7 0.0 1.5e-53 181.9 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.20 EME79634.1 - 0.00055 19.8 0.2 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase CMD PF02627.15 EME79636.1 - 6.1e-18 64.4 2.4 1.8e-08 34.1 0.5 3.1 3 0 0 3 3 3 3 Carboxymuconolactone decarboxylase family Bac_rhamnosid PF05592.6 EME79637.1 - 2.9e-52 177.5 0.0 2.9e-29 101.6 0.0 2.0 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase AFG1_ATPase PF03969.11 EME79638.1 - 1.4e-89 300.4 0.8 3.5e-83 279.4 0.1 3.1 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EME79638.1 - 0.00099 19.1 0.1 0.93 9.4 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EME79638.1 - 0.0035 17.4 0.0 0.059 13.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME79638.1 - 0.013 15.7 2.3 0.056 13.6 0.3 2.9 2 1 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EME79638.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.1 EME79638.1 - 0.087 12.8 0.0 1.9 8.5 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EME79638.1 - 0.092 12.9 0.2 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3409 PF11889.3 EME79640.1 - 0.11 12.1 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3409) zf-RING_2 PF13639.1 EME79641.1 - 2.4e-13 49.6 8.9 3.9e-13 48.9 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME79641.1 - 5e-10 39.3 2.9 8.9e-10 38.5 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME79641.1 - 6.4e-07 29.3 8.6 1e-06 28.6 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME79641.1 - 1.4e-06 27.8 8.6 2.1e-06 27.2 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME79641.1 - 3e-05 23.7 2.2 5.7e-05 22.8 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME79641.1 - 3e-05 23.6 8.1 4.7e-05 23.0 5.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME79641.1 - 6.3e-05 22.5 5.8 9.9e-05 21.9 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME79641.1 - 0.0012 18.4 3.1 0.0088 15.7 1.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EME79641.1 - 0.032 13.7 3.4 0.058 12.9 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EME79641.1 - 0.036 14.1 9.6 0.061 13.3 6.7 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EME79641.1 - 0.28 11.1 6.6 0.61 10.0 4.6 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EME79641.1 - 0.42 10.2 6.6 0.84 9.2 4.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EME79641.1 - 1.1 9.2 6.1 2.1 8.4 4.2 1.4 1 0 0 1 1 1 0 RING-like domain RNA_pol_I_TF PF04090.7 EME79643.1 - 8.5e-11 41.4 0.1 2.9e-09 36.4 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF1556 PF07590.6 EME79643.1 - 0.77 10.0 3.2 0.44 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) AIG2_2 PF13772.1 EME79644.1 - 3e-06 27.2 0.1 1.2e-05 25.3 0.1 2.0 1 1 0 1 1 1 1 AIG2-like family AIG2 PF06094.7 EME79644.1 - 1.3e-05 25.6 0.0 1.8e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DUF3659 PF12396.3 EME79647.1 - 0 1103.8 190.2 2.5e-23 81.5 2.2 18.4 18 0 0 18 18 18 17 Protein of unknown function (DUF3659) GCV_T_C PF08669.6 EME79647.1 - 6.2e-07 29.3 3.7 8.3 6.5 0.0 8.0 6 1 1 7 7 7 3 Glycine cleavage T-protein C-terminal barrel domain DUF883 PF05957.8 EME79647.1 - 0.0063 16.8 37.2 0.3 11.5 0.1 7.0 6 1 1 7 7 7 4 Bacterial protein of unknown function (DUF883) CBS PF00571.23 EME79647.1 - 2.1 8.1 7.9 70 3.3 0.2 6.2 5 0 0 5 5 5 0 CBS domain zf-HC5HC2H_2 PF13832.1 EME79651.1 - 5.3e-17 61.7 3.3 5.3e-17 61.7 2.3 4.0 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME79651.1 - 2.6e-15 56.3 2.7 2.6e-15 56.3 1.9 4.5 4 0 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 EME79651.1 - 1.1e-13 50.9 0.4 3.5e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 BAH domain PHD PF00628.24 EME79651.1 - 1.9e-11 43.4 48.6 1.4e-06 27.8 5.8 5.1 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.1 EME79651.1 - 1.5e-05 24.2 5.0 1.5e-05 24.2 3.5 5.1 5 0 0 5 5 5 2 PHD-finger Prok-RING_1 PF14446.1 EME79651.1 - 0.035 13.8 41.3 0.35 10.6 5.0 5.6 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 Dus PF01207.12 EME79653.1 - 2.4e-45 154.7 0.2 5.9e-45 153.4 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP-utilizers_C PF02896.13 EME79653.1 - 0.087 11.6 0.1 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain DUF3418 PF11898.3 EME79653.1 - 0.15 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Fasciclin PF02469.17 EME79654.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain VRR_NUC PF08774.6 EME79655.1 - 4.3e-17 61.9 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain HA2 PF04408.18 EME79656.1 - 2.9e-22 78.6 0.4 1.7e-21 76.1 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EME79656.1 - 5e-21 74.6 0.0 1.6e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EME79656.1 - 3.6e-13 49.1 0.0 9.2e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME79656.1 - 2.7e-07 30.2 0.0 6.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME79656.1 - 3.6e-05 23.9 0.0 8.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EME79656.1 - 0.00024 20.5 0.0 0.00063 19.2 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EME79656.1 - 0.00051 19.0 0.0 0.001 18.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EME79656.1 - 0.0014 18.4 0.0 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EME79656.1 - 0.0063 15.5 0.0 0.019 13.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EME79656.1 - 0.009 15.9 0.2 0.081 12.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.15 EME79656.1 - 0.013 14.2 0.7 0.025 13.2 0.5 1.5 1 0 0 1 1 1 0 G-protein alpha subunit KaiC PF06745.8 EME79656.1 - 0.017 14.2 0.1 0.035 13.2 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EME79656.1 - 0.048 13.3 1.4 0.74 9.4 0.1 2.6 3 0 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 EME79656.1 - 0.055 12.8 0.4 4.7 6.5 0.1 2.3 1 1 0 2 2 2 0 AAA-like domain Flavi_DEAD PF07652.9 EME79656.1 - 0.069 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.1 EME79656.1 - 0.1 12.9 0.5 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME79656.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EME79656.1 - 0.26 12.1 1.6 0.95 10.2 0.2 2.7 2 0 0 2 2 2 0 AAA domain Glyoxalase_2 PF12681.2 EME79657.1 - 6.9e-14 52.3 0.0 9.1e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME79657.1 - 7.3e-06 25.9 0.0 3.9e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3970 PF13113.1 EME79657.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) NIL PF09383.5 EME79657.1 - 0.087 12.4 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 NIL domain GST_C PF00043.20 EME79658.1 - 6.5e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME79658.1 - 4.1e-06 27.2 0.1 5.8e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME79658.1 - 0.00039 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME79658.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME79658.1 - 0.016 15.1 0.0 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Grp1_Fun34_YaaH PF01184.14 EME79659.1 - 4.3e-29 101.3 18.6 5.8e-29 100.8 12.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2614 PF11023.3 EME79659.1 - 1.2 8.8 4.6 0.66 9.7 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) DUF4577 PF15145.1 EME79659.1 - 2.4 8.0 3.7 1.3 8.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) DUF948 PF06103.6 EME79661.1 - 0.079 12.8 2.2 0.29 11.0 0.0 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EME79661.1 - 5.1 5.6 13.9 0.37 9.4 3.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein TIM21 PF08294.6 EME79662.1 - 2.3e-41 140.8 0.0 2.6e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EME79662.1 - 7.5e-05 22.2 0.0 0.00047 19.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_11 PF13414.1 EME79663.1 - 0.0017 17.9 3.3 0.0064 16.1 0.5 2.7 1 1 1 2 2 2 1 TPR repeat Alkyl_sulf_dimr PF14863.1 EME79663.1 - 0.012 15.8 1.4 0.11 12.6 0.2 2.6 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 EME79663.1 - 0.013 15.6 0.7 0.21 11.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat YopD PF05844.7 EME79663.1 - 0.021 13.8 0.7 0.028 13.4 0.5 1.2 1 0 0 1 1 1 0 YopD protein TPR_12 PF13424.1 EME79663.1 - 0.13 12.2 2.8 1 9.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME79663.1 - 0.19 12.4 0.3 0.19 12.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyoxalase PF00903.20 EME79664.1 - 9e-22 77.4 0.1 6e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EME79664.1 - 5.2e-13 48.9 0.1 4.4e-06 26.6 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME79664.1 - 4.8e-08 33.5 0.0 0.0024 18.4 0.0 3.1 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EME79664.1 - 9.4e-06 25.6 0.0 0.16 11.8 0.0 3.9 4 0 0 4 4 4 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EME79664.1 - 0.00016 21.6 0.0 0.028 14.3 0.0 3.0 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyco_hydro_1 PF00232.13 EME79665.1 - 8.6e-109 363.7 0.5 1.1e-108 363.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cyclin PF08613.6 EME79666.1 - 4.5e-23 82.3 0.0 5.2e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EME79666.1 - 0.0077 15.8 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mit_ribos_Mrp51 PF11709.3 EME79667.1 - 4.6e-56 190.3 0.0 1.9e-50 171.8 0.0 2.6 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit Peptidase_M24 PF00557.19 EME79668.1 - 2.3e-55 187.3 0.1 3e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EME79668.1 - 1.2e-25 89.4 0.0 2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Patatin PF01734.17 EME79669.1 - 7.7e-12 45.5 0.1 8.2e-12 45.4 0.1 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 EME79670.1 - 2.5e-06 27.5 0.0 7.9e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase ACBP PF00887.14 EME79671.1 - 1.1e-20 73.0 3.4 1.3e-20 72.8 2.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein UPF0223 PF05256.7 EME79671.1 - 0.31 11.1 2.2 0.62 10.2 1.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) AAA_23 PF13476.1 EME79671.1 - 0.72 10.1 5.2 0.84 9.9 3.6 1.1 1 0 0 1 1 1 0 AAA domain BTB PF00651.26 EME79672.1 - 4.3e-08 33.1 1.2 2.5e-07 30.6 0.8 2.1 1 1 0 1 1 1 1 BTB/POZ domain ADK PF00406.17 EME79673.1 - 1e-35 122.8 0.0 3e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EME79673.1 - 1.1e-15 56.9 0.0 1.8e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EME79673.1 - 1.9e-07 31.4 0.0 0.00031 21.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME79673.1 - 7.1e-05 23.6 0.1 0.00037 21.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME79673.1 - 0.0022 17.8 0.0 0.068 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EME79673.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LETM1 PF07766.8 EME79674.1 - 2.7e-105 351.2 0.4 2.7e-105 351.2 0.2 1.7 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 EME79674.1 - 1.2e-05 24.6 0.0 0.00099 18.5 0.0 2.9 3 0 0 3 3 3 1 SAP domain DHHW PF14286.1 EME79674.1 - 0.21 10.9 11.6 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 DHHW protein adh_short PF00106.20 EME79675.1 - 4.3e-26 91.8 0.2 5.8e-26 91.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME79675.1 - 3.8e-14 52.7 0.3 5.5e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME79675.1 - 1.3e-13 51.3 1.1 1.6e-13 50.9 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EME79675.1 - 0.0015 18.3 0.2 0.0042 16.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EME79675.1 - 0.0016 17.4 0.6 0.0022 16.9 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF619 PF04768.8 EME79676.1 - 2.8e-55 186.3 0.0 7.8e-55 184.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF619) SMC_N PF02463.14 EME79677.1 - 4.7e-65 218.9 0.0 1.5e-64 217.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME79677.1 - 1.2e-21 76.8 0.2 5.1e-21 74.8 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EME79677.1 - 1.7e-13 51.2 7.9 1.3e-06 28.6 0.6 3.1 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EME79677.1 - 4.7e-07 30.3 39.3 4.7e-07 30.3 27.3 6.9 3 2 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EME79677.1 - 0.00039 19.8 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EME79677.1 - 0.0021 16.6 18.1 0.0021 16.6 12.5 5.2 3 2 2 5 5 5 2 AAA domain TMF_DNA_bd PF12329.3 EME79677.1 - 0.0021 17.8 6.8 0.0021 17.8 4.7 11.6 7 4 3 10 10 8 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EME79677.1 - 0.0028 16.9 2.9 0.0028 16.9 2.0 5.4 4 2 2 7 7 7 2 Reovirus sigma C capsid protein Spc7 PF08317.6 EME79677.1 - 0.0035 16.0 13.8 0.0035 16.0 9.5 7.0 2 2 3 6 6 6 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 EME79677.1 - 0.0059 16.4 14.6 0.0059 16.4 10.1 8.0 4 2 3 8 8 8 1 Tropomyosin like ABC_tran PF00005.22 EME79677.1 - 6.5 7.0 28.4 0.89 9.8 0.0 6.1 3 2 0 3 3 3 0 ABC transporter DUF3896 PF13035.1 EME79677.1 - 9.1 6.4 11.1 0.094 12.7 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) DUF1537 PF07005.6 EME79678.1 - 1.3e-24 87.1 2.7 1.7e-24 86.7 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF1537 Glu_syn_central PF04898.9 EME79678.1 - 0.042 13.1 0.1 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain Rad51 PF08423.6 EME79679.1 - 1.4e-05 24.1 0.0 0.0053 15.6 0.0 2.8 2 1 0 2 2 2 1 Rad51 RecA PF00154.16 EME79679.1 - 2.5e-05 23.4 0.2 5.9e-05 22.2 0.1 1.6 1 1 1 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EME79679.1 - 0.00095 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EME79679.1 - 0.0013 18.1 0.9 0.0083 15.5 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME79679.1 - 0.0039 17.1 0.1 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EME79679.1 - 0.004 16.0 0.1 0.057 12.2 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.12 EME79679.1 - 0.0062 15.9 0.6 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.24 EME79679.1 - 0.01 16.0 0.0 0.027 14.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EME79679.1 - 0.024 13.8 0.2 0.038 13.2 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EME79679.1 - 0.036 14.3 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EME79679.1 - 0.045 13.4 0.1 0.23 11.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EME79679.1 - 0.047 14.5 0.0 0.18 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EME79679.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain SSXRD PF09514.5 EME79679.1 - 0.13 11.6 1.0 0.23 10.8 0.7 1.4 1 0 0 1 1 1 0 SSXRD motif Arch_ATPase PF01637.13 EME79679.1 - 0.18 11.4 0.0 0.74 9.4 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase YwiC PF14256.1 EME79680.1 - 0.082 13.0 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 YwiC-like protein GST_C_3 PF14497.1 EME79681.1 - 0.022 15.2 0.7 0.25 11.8 0.1 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3844 PF12955.2 EME79682.1 - 1.1e-33 115.3 3.2 1.7e-33 114.7 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) CMAS PF02353.15 EME79683.1 - 0.011 14.8 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1757 PF08560.5 EME79684.1 - 2e-05 24.3 0.1 2.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) CDP-OH_P_transf PF01066.16 EME79685.1 - 1.7e-15 57.1 3.0 1.7e-15 57.1 2.1 2.9 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Sugar_tr PF00083.19 EME79689.1 - 3.5e-121 404.9 24.2 3.9e-121 404.7 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79689.1 - 1.1e-17 63.8 37.3 1.1e-17 63.8 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CUE PF02845.11 EME79690.1 - 3.9e-12 45.4 0.0 6.1e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain ASD1 PF08688.5 EME79690.1 - 0.004 16.9 1.0 0.0042 16.8 0.2 1.5 2 0 0 2 2 2 1 Apx/Shroom domain ASD1 Lipase_GDSL PF00657.17 EME79691.1 - 1e-16 61.4 0.3 1.5e-16 60.9 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pro_isomerase PF00160.16 EME79692.1 - 6.8e-42 143.3 0.0 7.6e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP2_3 PF14378.1 EME79693.1 - 9.5e-19 67.6 22.7 3e-16 59.4 4.3 2.5 3 0 0 3 3 3 2 PAP2 superfamily DUF1129 PF06570.6 EME79693.1 - 0.0094 15.2 1.5 0.0094 15.2 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) RtcB PF01139.12 EME79693.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB EH_Signature PF15611.1 EME79695.1 - 0.0074 15.3 0.1 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 EH_Signature domain PAN_4 PF14295.1 EME79695.1 - 0.018 14.7 2.7 0.018 14.7 1.9 1.8 2 0 0 2 2 2 0 PAN domain DUF4066 PF13278.1 EME79696.1 - 5e-28 97.4 0.0 6.7e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EME79696.1 - 1.5e-08 34.1 0.1 1e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ORC4_C PF14629.1 EME79697.1 - 1.2e-25 90.0 0.1 7.9e-25 87.4 0.1 2.0 1 1 1 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EME79697.1 - 3.1e-18 66.4 1.7 3.4e-16 59.7 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME79697.1 - 2.3e-09 37.4 0.0 5.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EME79697.1 - 3e-06 27.4 0.0 6.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EME79697.1 - 2.2e-05 24.1 0.2 0.00014 21.5 0.2 2.0 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EME79697.1 - 2.9e-05 23.1 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EME79697.1 - 0.00018 21.2 0.0 0.00032 20.4 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EME79697.1 - 0.00053 18.9 0.2 0.001 17.9 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 EME79697.1 - 0.0022 17.4 0.1 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EME79697.1 - 0.0031 16.9 0.0 0.77 9.1 0.0 2.6 2 1 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EME79697.1 - 0.0036 17.2 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EME79697.1 - 0.012 14.9 0.1 0.057 12.6 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 EME79697.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein KAP_NTPase PF07693.9 EME79697.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.1 EME79697.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME79697.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EME79697.1 - 0.024 14.0 0.0 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EME79697.1 - 0.045 14.5 0.0 0.16 12.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EME79697.1 - 0.047 13.5 0.1 0.15 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3912 PF13051.1 EME79697.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) G-alpha PF00503.15 EME79697.1 - 0.051 12.2 0.2 0.19 10.4 0.1 1.8 1 1 0 1 1 1 0 G-protein alpha subunit VWA_2 PF13519.1 EME79697.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain PduV-EutP PF10662.4 EME79697.1 - 0.085 12.3 0.0 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EME79697.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) zf-BED PF02892.10 EME79698.1 - 0.024 14.4 0.1 1.8 8.4 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger DUF2968 PF11180.3 EME79698.1 - 0.57 9.5 14.4 1.2 8.4 10.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HOOK PF05622.7 EME79699.1 - 0.0041 14.9 0.7 0.0056 14.5 0.5 1.1 1 0 0 1 1 1 1 HOOK protein HALZ PF02183.13 EME79699.1 - 0.043 13.5 0.4 0.08 12.6 0.3 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Sds3 PF08598.6 EME79699.1 - 0.046 13.2 4.0 0.079 12.4 2.8 1.3 1 0 0 1 1 1 0 Sds3-like ERM PF00769.14 EME79699.1 - 0.047 13.2 2.7 0.076 12.5 1.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EME79699.1 - 0.1 12.9 0.9 0.21 11.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EME79699.1 - 0.18 10.8 2.4 0.24 10.4 1.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Adeno_VII PF03228.9 EME79699.1 - 0.36 11.4 2.5 0.78 10.3 1.8 1.5 1 0 0 1 1 1 0 Adenoviral core protein VII SpaB_C PF14028.1 EME79699.1 - 0.68 9.4 5.5 5.3 6.5 3.8 1.9 1 1 0 1 1 1 0 SpaB C-terminal domain ATP_synt_H PF05493.8 EME79700.1 - 2e-26 91.7 3.4 2.3e-26 91.6 2.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H YfhO PF09586.5 EME79700.1 - 0.031 12.3 0.7 0.033 12.2 0.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.1 EME79700.1 - 0.032 13.6 0.6 0.034 13.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MscS_TM PF12794.2 EME79700.1 - 0.28 9.7 7.1 0.31 9.5 4.9 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ABC2_membrane_4 PF12730.2 EME79700.1 - 0.38 9.8 4.6 0.44 9.6 3.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NicO PF03824.11 EME79700.1 - 0.54 9.5 2.8 0.59 9.3 2.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Arv1 PF04161.8 EME79701.1 - 5.8e-46 157.0 0.0 7.6e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family PAN_1 PF00024.21 EME79702.1 - 0.0038 16.9 1.3 0.0038 16.9 0.9 1.9 2 0 0 2 2 2 1 PAN domain zf-ribbon_3 PF13248.1 EME79702.1 - 0.008 15.3 0.3 0.018 14.2 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DSL PF01414.14 EME79702.1 - 0.01 15.8 3.1 0.03 14.3 2.2 1.8 1 0 0 1 1 1 0 Delta serrate ligand zf-C2H2_4 PF13894.1 EME79702.1 - 0.071 13.4 0.2 0.43 11.0 0.1 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EME79702.1 - 0.081 13.3 0.3 0.26 11.7 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Na_H_Exchanger PF00999.16 EME79703.1 - 1.6e-67 227.7 42.9 1.9e-67 227.4 29.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family LacAB_rpiB PF02502.13 EME79704.1 - 4e-41 139.9 0.2 4.7e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 EME79704.1 - 0.073 12.9 0.5 0.26 11.1 0.0 2.0 2 1 1 3 3 3 0 Glycine-rich SFCGS MFS_1 PF07690.11 EME79707.1 - 5.8e-27 94.3 28.1 5.8e-27 94.3 19.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.15 EME79708.1 - 1e-58 198.8 0.1 1.3e-58 198.5 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CorA PF01544.13 EME79709.1 - 1.9e-05 23.8 5.5 2.1e-05 23.7 1.8 2.1 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Bac_rhamnosid PF05592.6 EME79711.1 - 4.8e-21 74.5 1.2 1.1e-08 33.7 0.0 3.9 3 1 1 4 4 4 4 Bacterial alpha-L-rhamnosidase SLT PF01464.15 EME79712.1 - 6.6e-10 38.5 0.0 1.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain RRM_1 PF00076.17 EME79715.1 - 3.6e-30 103.4 0.1 4.8e-14 51.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME79715.1 - 3.9e-23 81.2 0.0 2.1e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME79715.1 - 3e-17 62.2 0.0 8.2e-05 22.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME79715.1 - 0.17 11.6 0.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif p450 PF00067.17 EME79716.1 - 4.9e-36 124.2 0.2 6.2e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_11 PF14833.1 EME79717.1 - 1.9e-39 134.4 1.3 2.8e-26 91.9 0.2 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EME79717.1 - 8e-39 133.0 0.0 1.5e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EME79717.1 - 0.00052 19.2 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME79717.1 - 0.0018 18.6 0.0 0.0048 17.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EME79717.1 - 0.0019 17.5 0.0 0.85 8.9 0.1 3.0 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EME79717.1 - 0.0036 16.9 0.4 0.011 15.3 0.0 2.0 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTHFR PF02219.12 EME79718.1 - 2e-111 371.6 0.0 2.7e-111 371.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase adh_short_C2 PF13561.1 EME79719.1 - 2.3e-28 99.5 0.0 3.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME79719.1 - 2.7e-25 89.1 0.8 3.9e-25 88.6 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME79719.1 - 1.3e-14 54.3 0.5 1.9e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EME79719.1 - 0.005 15.5 0.1 0.01 14.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Transketolase_N PF00456.16 EME79720.1 - 3.4e-121 404.1 0.0 5.3e-121 403.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EME79720.1 - 2.6e-39 134.5 0.0 1.4e-38 132.1 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EME79720.1 - 1.8e-06 27.1 0.0 0.0014 17.5 0.0 3.1 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EME79720.1 - 2.2e-05 23.3 0.1 4.3e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EME79720.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain Glucosaminidase PF01832.15 EME79720.1 - 0.077 13.1 0.4 0.15 12.1 0.3 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase FA_desaturase PF00487.19 EME79721.1 - 9.2e-20 71.1 13.2 9.2e-20 71.1 9.1 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EME79721.1 - 4.3e-16 58.4 0.1 1e-15 57.2 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TerD PF02342.13 EME79722.1 - 0.057 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 TerD domain AAA_12 PF13087.1 EME79723.1 - 2.8e-13 49.7 0.0 2.9e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EME79723.1 - 0.0095 16.0 0.0 0.016 15.2 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain VWA_3 PF13768.1 EME79724.1 - 0.04 13.6 0.0 0.047 13.3 0.0 1.0 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2217 PF10265.4 EME79725.1 - 0.14 10.8 5.7 0.22 10.2 4.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_capsid PF06112.6 EME79725.1 - 0.3 11.1 14.8 0.66 10.0 10.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF966 PF06136.8 EME79725.1 - 0.48 9.7 15.5 0.087 12.2 8.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DDHD PF02862.12 EME79725.1 - 1.4 8.6 9.4 3 7.5 6.5 1.5 1 0 0 1 1 1 0 DDHD domain RAP1 PF07218.6 EME79725.1 - 5.6 4.9 11.4 8.5 4.3 7.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ndc1_Nup PF09531.5 EME79725.1 - 7 4.9 8.1 7.9 4.7 5.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Alpha-L-AF_C PF06964.7 EME79726.1 - 1.8e-30 106.0 0.0 6.4e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus Racemase_4 PF13615.1 EME79727.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative alanine racemase OGG_N PF07934.7 EME79729.1 - 1e-32 112.5 0.0 1.9e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EME79729.1 - 2.8e-13 50.0 0.0 5.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EME79729.1 - 0.00041 19.8 0.0 0.00099 18.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Selenoprotein_S PF06936.6 EME79729.1 - 0.46 9.9 3.3 0.69 9.4 2.3 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) MKT1_C PF12246.3 EME79730.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication SNARE PF05739.14 EME79731.1 - 2.2e-07 30.4 2.3 2.2e-07 30.4 1.6 2.3 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 EME79731.1 - 0.0081 16.2 8.0 0.092 12.8 1.2 3.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus LANC_like PF05147.8 EME79732.1 - 1.7e-26 92.6 0.0 2.6e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.5 EME79732.1 - 0.0065 15.6 0.0 0.026 13.6 0.0 1.8 1 1 0 1 1 1 1 Pectic acid lyase BIR PF00653.16 EME79733.1 - 0.014 15.8 0.3 0.042 14.2 0.0 1.9 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain APH PF01636.18 EME79734.1 - 6.7e-11 42.3 0.0 7.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME79734.1 - 0.0042 16.7 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EME79734.1 - 0.15 11.3 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family KH_1 PF00013.24 EME79735.1 - 0.00089 18.8 0.1 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EME79735.1 - 0.027 14.1 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 KH domain U79_P34 PF03064.11 EME79735.1 - 5.2 6.5 16.8 9.7 5.6 11.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 adh_short PF00106.20 EME79736.1 - 5.7e-07 29.5 0.6 6.8e-07 29.3 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EME79736.1 - 6.3e-06 25.2 0.1 6.9e-06 25.1 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EME79736.1 - 0.00011 21.9 0.2 0.00013 21.7 0.1 1.0 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EME79736.1 - 0.0064 16.8 0.1 0.0076 16.6 0.1 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EME79736.1 - 0.036 14.1 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EME79736.1 - 0.083 11.9 0.2 1.3 8.0 0.1 1.9 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fungal_lectin PF07938.7 EME79737.1 - 0.0034 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Fungal fucose-specific lectin Dak2 PF02734.12 EME79739.1 - 7.3e-40 136.4 0.1 3.3e-39 134.3 0.0 2.0 2 0 0 2 2 2 1 DAK2 domain OsmC PF02566.14 EME79740.1 - 4.6e-15 55.6 0.1 1.4e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 OsmC-like protein Transmemb_17 PF09799.4 EME79741.1 - 0.0059 16.9 0.2 0.0088 16.3 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein YqjK PF13997.1 EME79741.1 - 1.9 8.7 6.4 2 8.6 0.0 2.8 3 0 0 3 3 3 0 YqjK-like protein Fungal_trans PF04082.13 EME79742.1 - 1.1e-12 47.3 0.1 3e-12 45.9 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EME79742.1 - 1.2e-07 31.6 9.9 9.1e-05 22.5 2.6 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME79742.1 - 1e-05 25.4 16.4 0.00037 20.6 4.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EME79742.1 - 0.0028 17.7 4.6 0.0063 16.6 3.2 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EME79742.1 - 0.0062 16.8 19.6 0.024 14.9 4.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EME79742.1 - 0.52 10.5 7.0 0.19 11.9 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TIM PF00121.13 EME79744.1 - 2.3e-58 197.1 0.0 2.6e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase HBS1_N PF08938.5 EME79744.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Fungal_trans_2 PF11951.3 EME79745.1 - 1.6e-15 56.6 8.1 2.6e-15 55.9 5.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79745.1 - 4.4e-06 26.5 11.6 8.4e-06 25.5 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOT2_3_5 PF04153.13 EME79746.1 - 1.5e-27 96.1 0.5 1.9e-27 95.7 0.3 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pro-kuma_activ PF09286.6 EME79747.1 - 7e-46 155.8 0.2 1.6e-45 154.6 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME79747.1 - 7.5e-08 31.8 0.7 1.3e-07 31.0 0.5 1.3 1 0 0 1 1 1 1 Subtilase family EBP50_C-term PF09007.6 EME79747.1 - 0.03 14.1 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 EBP50, C-terminal FAD_binding_2 PF00890.19 EME79749.1 - 1.1e-119 399.9 4.4 1.5e-119 399.6 3.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EME79749.1 - 3.6e-42 143.2 1.1 5.4e-42 142.6 0.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EME79749.1 - 4.3e-06 26.7 0.2 0.00081 19.3 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME79749.1 - 1.1e-05 24.4 1.0 0.0069 15.2 1.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EME79749.1 - 6.6e-05 22.1 0.2 0.021 13.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EME79749.1 - 0.0005 19.0 0.3 0.0021 17.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME79749.1 - 0.0049 15.9 0.5 0.0086 15.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME79749.1 - 0.074 11.5 4.5 0.16 10.3 0.5 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 EME79749.1 - 0.4 10.7 2.3 7.5 6.5 0.7 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.13 EME79751.1 - 6.3e-15 54.5 31.0 2.4e-14 52.6 21.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short_C2 PF13561.1 EME79752.1 - 1.6e-23 83.7 0.0 2.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME79752.1 - 5.7e-18 65.3 0.1 8.7e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Yip1 PF04893.12 EME79753.1 - 3.2e-14 52.8 13.6 5e-14 52.1 9.4 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EME79753.1 - 0.012 15.2 7.7 0.021 14.5 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Choline_kinase PF01633.15 EME79754.1 - 0.00029 20.4 0.0 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EME79754.1 - 0.00076 19.2 0.0 0.23 11.1 0.0 3.2 4 0 0 4 4 4 1 Phosphotransferase enzyme family Kelch_1 PF01344.20 EME79754.1 - 0.34 10.4 3.0 2.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Kelch motif ketoacyl-synt PF00109.21 EME79755.1 - 4.3e-71 239.3 0.0 1.2e-70 237.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EME79755.1 - 1.4e-49 169.1 0.4 2.9e-49 168.1 0.3 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EME79755.1 - 8.2e-45 152.6 0.3 2.6e-43 147.8 0.0 2.5 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EME79755.1 - 6.1e-43 146.6 0.3 2.4e-38 131.6 0.0 3.5 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 EME79755.1 - 1.3e-38 132.8 0.5 2.9e-38 131.7 0.4 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 EME79755.1 - 5.8e-38 130.2 0.0 1.2e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EME79755.1 - 1.7e-20 73.0 0.5 2.4e-18 66.1 0.3 2.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EME79755.1 - 8.9e-17 61.3 0.0 2.7e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME79755.1 - 1.4e-14 54.1 0.0 3.9e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EME79755.1 - 2e-14 53.5 0.0 5.4e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME79755.1 - 3e-10 39.2 0.0 5.5e-08 31.8 0.0 2.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.7 EME79755.1 - 8.9e-09 35.7 0.0 2.9e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME79755.1 - 3.7e-08 33.9 0.0 1.5e-06 28.7 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME79755.1 - 8.3e-08 31.9 0.0 2.4e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EME79755.1 - 0.00027 21.1 0.3 0.0012 19.0 0.2 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EME79755.1 - 0.00076 18.6 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EME79755.1 - 0.0027 16.7 0.0 0.0064 15.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.12 EME79755.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2024 PF09630.5 EME79755.1 - 0.18 11.5 0.1 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) ADH_zinc_N PF00107.21 EME79756.1 - 2e-08 33.8 0.0 4.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME79756.1 - 3.8e-06 26.6 0.1 0.003 17.2 0.1 3.1 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EME79757.1 - 7.6e-49 166.4 0.0 8.4e-46 156.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF788 PF05620.6 EME79757.1 - 0.49 10.2 0.0 0.49 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) adh_short PF00106.20 EME79760.1 - 1e-13 51.5 0.0 1.7e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME79760.1 - 0.00033 20.3 0.0 0.00089 18.9 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EME79760.1 - 0.0021 18.0 0.1 0.013 15.5 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EME79760.1 - 0.0035 16.7 0.0 0.009 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EME79760.1 - 0.032 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.1 EME79760.1 - 0.13 11.9 0.0 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase F-box-like_2 PF13013.1 EME79762.1 - 0.03 14.0 0.2 0.065 12.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain SRF-TF PF00319.13 EME79764.1 - 4.6e-24 83.3 0.0 6.7e-24 82.8 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ubiquitin PF00240.18 EME79765.1 - 9.4e-11 40.9 0.0 2.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EME79765.1 - 4.6e-07 29.4 0.0 0.03 14.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Xpo1 PF08389.7 EME79766.1 - 1.5e-25 89.8 7.7 1.9e-25 89.4 0.3 3.8 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EME79766.1 - 1.6e-05 24.6 1.7 9.3e-05 22.2 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EME79766.1 - 0.00031 20.9 0.1 0.012 15.8 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 EME79766.1 - 0.00081 17.8 0.5 0.036 12.3 0.1 2.3 2 0 0 2 2 2 1 Adaptin N terminal region Syntaxin PF00804.20 EME79766.1 - 0.0037 17.3 0.6 0.98 9.6 0.0 3.5 3 0 0 3 3 3 1 Syntaxin HEAT PF02985.17 EME79766.1 - 0.0076 16.2 0.4 9.5 6.6 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EME79766.1 - 0.014 15.9 0.3 0.24 11.9 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat LSM PF01423.17 EME79767.1 - 1.2e-16 60.0 0.3 1.5e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EME79767.1 - 0.093 12.1 0.1 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PhnA protein 5-FTHF_cyc-lig PF01812.15 EME79768.1 - 2.6e-38 131.6 0.0 3.7e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EME79769.1 - 1.2e-85 286.2 0.1 1.4e-85 286.0 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Lipocalin_4 PF13648.1 EME79769.1 - 0.0052 17.3 0.5 0.0083 16.7 0.4 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Flavi_NS1 PF00948.16 EME79770.1 - 0.063 11.6 0.0 0.083 11.2 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 SAP30_Sin3_bdg PF13867.1 EME79771.1 - 8.5e-07 28.7 0.1 1.4e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 MFS_1 PF07690.11 EME79773.1 - 4.6e-45 153.8 54.1 6.9e-45 153.2 37.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME79773.1 - 1.9e-20 72.5 24.2 2.6e-20 72.1 16.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EME79773.1 - 2.7e-19 69.0 5.7 2.7e-19 69.0 3.9 3.5 3 1 0 4 4 4 2 Sugar (and other) transporter DUF2614 PF11023.3 EME79773.1 - 0.15 11.8 1.1 0.49 10.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) PX PF00787.19 EME79775.1 - 4.3e-21 74.8 0.0 5.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 PX domain PAN_3 PF08277.7 EME79776.1 - 0.0024 17.4 2.6 0.005 16.4 1.8 1.6 1 0 0 1 1 1 1 PAN-like domain Gamma-thionin PF00304.15 EME79776.1 - 9.6 6.3 16.3 14 5.8 3.7 3.2 2 1 0 2 2 2 0 Gamma-thionin family Sec1 PF00995.18 EME79777.1 - 4.8e-119 398.5 0.0 5.4e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.1 EME79778.1 - 3.7e-41 141.2 0.0 4.8e-35 121.1 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EME79778.1 - 7.1e-19 68.0 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME79778.1 - 2.9e-11 43.1 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EME79778.1 - 1.2e-05 24.2 0.1 0.0048 15.7 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EME79778.1 - 0.0069 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs DEC-1_N PF04625.8 EME79780.1 - 0.17 10.4 3.7 0.22 10.1 2.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region tRNA-synt_1 PF00133.17 EME79781.1 - 6.4e-215 714.6 0.4 5.7e-214 711.5 0.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME79781.1 - 5.4e-31 107.4 0.0 1.3e-30 106.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME79781.1 - 2.1e-17 62.9 0.7 5.1e-08 31.9 0.0 5.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EME79781.1 - 7.2e-08 31.9 12.7 2.8e-07 29.9 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EME79781.1 - 0.11 11.3 5.0 0.28 9.9 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EME79781.1 - 0.27 10.3 4.5 0.41 9.7 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_4 PF13894.1 EME79782.1 - 3.8e-05 23.7 2.6 3.8e-05 23.7 1.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EME79782.1 - 0.00016 21.8 2.1 0.00016 21.8 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME79782.1 - 4 7.9 10.7 1.2 9.5 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EME79784.1 - 0.46 10.9 32.3 0.038 14.3 1.2 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type Zn_clus PF00172.13 EME79785.1 - 1.3e-05 25.0 11.0 2.4e-05 24.1 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 EME79788.1 - 8.2e-21 74.9 0.0 3.5e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME79788.1 - 5.5e-15 55.1 0.0 8.8e-14 51.1 0.0 2.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EME79788.1 - 5.9e-12 44.5 0.0 2.1e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME79788.1 - 4.1e-10 39.8 0.0 2.2e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME79788.1 - 0.0054 16.7 0.1 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME79788.1 - 0.0056 16.4 0.1 0.05 13.3 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EME79788.1 - 0.0089 15.1 0.0 4.2 6.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 EME79788.1 - 0.015 14.2 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.19 EME79788.1 - 0.12 11.2 1.9 3 6.6 0.2 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME79788.1 - 0.16 12.4 0.1 22 5.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2416 PF10315.4 EME79788.1 - 0.22 11.7 1.7 0.29 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2416) DUF423 PF04241.10 EME79791.1 - 1.9e-23 82.1 2.4 2.7e-23 81.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) YiaAB PF05360.9 EME79791.1 - 1.3 8.6 6.1 1.1 8.8 0.1 3.0 3 0 0 3 3 3 0 yiaA/B two helix domain Topoisom_I_N PF02919.10 EME79792.1 - 1.3e-96 322.0 6.3 1.3e-96 322.0 4.3 3.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EME79792.1 - 2e-83 279.1 7.0 2e-83 279.1 4.8 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EME79792.1 - 3.3e-32 109.9 0.3 1.3e-31 108.0 0.2 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EME79792.1 - 0.087 11.9 0.1 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family YjgP_YjgQ PF03739.9 EME79792.1 - 0.47 9.1 3.1 0.96 8.1 2.1 1.5 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family ATP-synt PF00231.14 EME79793.1 - 1.2e-74 251.3 3.6 1.3e-74 251.1 2.5 1.0 1 0 0 1 1 1 1 ATP synthase Sec20 PF03908.8 EME79794.1 - 3.1e-16 58.8 0.8 3.1e-16 58.8 0.6 2.6 3 1 0 3 3 3 1 Sec20 CorA PF01544.13 EME79794.1 - 2.3 7.1 9.1 1.9 7.4 1.0 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein T2SF PF00482.18 EME79794.1 - 3.2 7.6 5.7 18 5.2 0.3 2.9 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein F DUF342 PF03961.8 EME79794.1 - 5.2 5.3 11.8 0.027 12.8 1.3 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF342) COPIIcoated_ERV PF07970.7 EME79795.1 - 4.3e-70 235.7 0.1 8.2e-46 156.4 0.0 2.4 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EME79795.1 - 5.2e-33 112.9 0.0 1.8e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) YjbE PF11106.3 EME79797.1 - 0.16 11.9 1.5 0.28 11.1 1.0 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE MR_MLE_C PF13378.1 EME79798.1 - 1.4e-19 70.1 0.0 3.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EME79798.1 - 3.2e-13 50.0 0.0 1.9e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EME79798.1 - 0.0029 16.5 0.0 0.0048 15.8 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF4375 PF14300.1 EME79798.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) PepSY PF03413.14 EME79798.1 - 0.16 12.6 0.4 0.92 10.2 0.1 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Sugar_tr PF00083.19 EME79799.1 - 9.3e-84 281.5 28.9 2.6e-82 276.7 20.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79799.1 - 1.3e-11 43.8 44.4 1.9e-05 23.5 14.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily UPRTase PF14681.1 EME79800.1 - 1.6e-35 122.1 0.3 3.1e-35 121.2 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 EME79800.1 - 3.9e-09 36.9 0.0 9.4e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME79800.1 - 1.4e-06 28.8 0.0 2.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 EME79800.1 - 0.00065 18.8 0.1 0.14 11.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 EME79800.1 - 0.002 17.9 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EME79800.1 - 0.0033 16.8 0.2 0.0091 15.4 0.2 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EME79800.1 - 0.0048 16.5 0.4 2.2 7.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain Pribosyltran PF00156.22 EME79800.1 - 0.0074 16.0 1.9 0.0074 16.0 1.3 3.0 3 1 0 3 3 3 1 Phosphoribosyl transferase domain AAA_17 PF13207.1 EME79800.1 - 0.013 16.3 0.0 0.077 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EME79800.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Hydrolase_3 PF08282.7 EME79800.1 - 0.026 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_14 PF13173.1 EME79800.1 - 0.037 13.9 0.1 0.56 10.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EME79800.1 - 0.059 13.2 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EME79800.1 - 0.059 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain PRTase_2 PF15609.1 EME79800.1 - 0.078 12.2 0.1 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase NB-ARC PF00931.17 EME79800.1 - 0.11 11.3 0.8 0.25 10.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 EME79800.1 - 0.12 12.5 0.0 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EME79800.1 - 0.16 11.5 0.1 3 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Tantalus PF15386.1 EME79802.1 - 0.088 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like DUF2771 PF10969.3 EME79802.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) SnoaL_4 PF13577.1 EME79803.1 - 4e-24 84.9 0.4 4.9e-24 84.6 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EME79803.1 - 7.5e-06 26.4 0.1 9.5e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Putative lumazine-binding DUF4440 PF14534.1 EME79803.1 - 0.00027 21.0 0.3 0.00037 20.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EME79803.1 - 0.00033 21.0 0.2 0.00053 20.3 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EME79803.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase NTF2 PF02136.15 EME79803.1 - 0.084 13.2 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Sugar_tr PF00083.19 EME79804.1 - 1.9e-80 270.6 22.9 1.9e-80 270.6 15.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79804.1 - 2.8e-16 59.1 26.6 2.8e-16 59.1 18.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MerE PF05052.7 EME79804.1 - 0.033 14.1 2.3 0.28 11.1 1.6 2.6 1 0 0 1 1 1 0 MerE protein Metallophos PF00149.23 EME79805.1 - 7.8e-12 45.0 5.3 1.5e-11 44.0 3.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase GTP_EFTU PF00009.22 EME79806.1 - 5.3e-43 146.6 0.0 7.9e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EME79806.1 - 3.6e-26 91.0 0.0 1.3e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EME79806.1 - 2e-17 62.8 0.0 8.6e-17 60.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME79806.1 - 8.9e-09 35.3 0.1 2.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EME79806.1 - 1.4e-06 28.0 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EME79806.1 - 8.4e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME79806.1 - 0.0032 17.9 0.0 0.0093 16.4 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EME79806.1 - 0.022 14.0 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.5 EME79806.1 - 0.053 12.7 0.1 0.45 9.7 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.18 EME79807.1 - 2.6e-97 324.9 1.5 2.8e-97 324.8 0.5 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME79807.1 - 1.1e-45 154.0 1.1 1.1e-45 154.0 0.7 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME79807.1 - 4.8e-06 26.2 4.7 2.5e-05 23.8 1.5 3.0 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EME79807.1 - 0.00042 19.9 3.5 0.039 13.5 0.1 2.8 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 EME79807.1 - 0.0052 15.2 0.7 0.013 13.9 0.1 1.8 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ACP_syn_III_C PF08541.5 EME79807.1 - 0.085 12.8 0.1 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Sugar_tr PF00083.19 EME79808.1 - 3.7e-114 381.7 21.7 4.3e-114 381.5 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79808.1 - 1.6e-19 69.8 25.4 1.6e-19 69.8 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EME79808.1 - 0.0028 16.4 2.0 0.19 10.4 1.4 2.2 1 1 0 1 1 1 1 BT1 family COesterase PF00135.23 EME79809.1 - 7e-09 34.9 0.0 8.3e-09 34.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family AP_endonuc_2 PF01261.19 EME79811.1 - 1.3e-13 50.7 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DLH PF01738.13 EME79812.1 - 2.6e-30 105.3 0.0 2.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME79812.1 - 4.3e-06 26.5 0.0 5.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME79812.1 - 0.00017 21.5 0.1 0.00036 20.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME79812.1 - 0.02 13.7 0.0 0.043 12.6 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Pro_dh PF01619.13 EME79814.1 - 1e-32 113.4 0.0 7.1e-32 110.6 0.0 1.9 1 1 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.17 EME79815.1 - 2.2e-95 319.6 0.0 2.7e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.19 EME79816.1 - 1.1e-38 133.1 0.0 1.3e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME79816.1 - 3.6e-05 23.7 0.0 9.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME79816.1 - 0.00089 19.6 0.0 0.0042 17.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME79816.1 - 0.0019 17.3 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EME79816.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME79816.1 - 0.007 16.1 0.0 0.049 13.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EME79816.1 - 0.0088 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EME79816.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 EME79816.1 - 0.0099 14.9 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EME79816.1 - 0.021 14.7 0.0 0.15 11.9 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EME79816.1 - 0.043 13.9 0.0 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EME79816.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family Trp_halogenase PF04820.9 EME79816.1 - 0.068 11.7 0.1 3.9 6.0 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase RPE65 PF03055.10 EME79817.1 - 2.2e-84 283.7 0.0 2.8e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zip PF02535.17 EME79818.1 - 8.4 5.2 9.2 3.9 6.3 5.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2235 PF09994.4 EME79819.1 - 9.1e-74 248.2 0.2 1.1e-73 248.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) NTS_2 PF15448.1 EME79819.1 - 0.00094 19.4 0.6 0.024 14.9 0.2 2.4 2 0 0 2 2 2 1 N-terminal segments of P. falciparum erythrocyte membrane protein Abhydrolase_5 PF12695.2 EME79819.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EME79819.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Methyltransf_6 PF03737.10 EME79821.1 - 1.3e-30 106.2 0.0 1.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Dioxygenase_C PF00775.16 EME79822.1 - 3.1e-11 42.8 0.0 5.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Zn_clus PF00172.13 EME79823.1 - 1.9e-07 30.8 13.1 3e-07 30.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EME79823.1 - 0.78 9.0 11.4 0.95 8.7 7.9 1.1 1 0 0 1 1 1 0 Vta1 like Golgin_A5 PF09787.4 EME79823.1 - 4 5.8 6.9 0.15 10.6 0.5 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cys_Met_Meta_PP PF01053.15 EME79824.1 - 1.3e-133 445.0 0.0 1.5e-133 444.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME79824.1 - 9.2e-06 24.9 0.1 1.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EME79824.1 - 2.2e-05 23.3 0.1 3.8e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EME79824.1 - 7.7e-05 21.5 0.1 0.00013 20.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.8 EME79824.1 - 0.00015 20.6 0.3 0.00044 19.0 0.2 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase POTRA_2 PF08479.6 EME79824.1 - 0.022 14.4 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 POTRA domain, ShlB-type Beta_elim_lyase PF01212.16 EME79824.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AAA_17 PF13207.1 EME79825.1 - 0.00065 20.5 0.1 0.0026 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EME79825.1 - 0.0024 16.6 0.0 0.071 11.8 0.0 2.1 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 EME79825.1 - 0.011 15.9 0.0 0.092 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EME79825.1 - 0.047 13.1 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EME79825.1 - 0.056 13.3 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EME79825.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EME79825.1 - 0.096 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.12 EME79825.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase UPF0079 PF02367.12 EME79825.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EME79825.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EME79825.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain adh_short PF00106.20 EME79826.1 - 7.3e-63 211.4 3.6 2.9e-32 111.8 0.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EME79826.1 - 1.1e-30 106.6 0.7 2.2e-15 56.7 0.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EME79826.1 - 1.8e-30 104.8 0.0 4.8e-30 103.4 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain RRM_4 PF10598.4 EME79826.1 - 0.047 13.5 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 THF_DHG_CYH_C PF02882.14 EME79826.1 - 0.058 12.4 0.1 8.6 5.4 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PALP PF00291.20 EME79826.1 - 1.3 8.1 7.1 0.41 9.8 0.1 2.7 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme ArfGap PF01412.13 EME79827.1 - 7e-35 119.3 0.5 1.3e-34 118.4 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Choline_transpo PF04515.7 EME79828.1 - 1.4e-96 323.1 19.8 1.4e-96 323.1 13.7 2.1 1 1 1 2 2 2 2 Plasma-membrane choline transporter Peptidase_M56 PF05569.6 EME79828.1 - 2.4 7.0 0.0 2.4 7.0 0.0 3.1 2 1 1 3 3 3 0 BlaR1 peptidase M56 Mannitol_dh_C PF08125.8 EME79829.1 - 1.8e-50 171.3 0.1 2.6e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EME79829.1 - 1.5e-18 67.1 0.2 5.2e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EME79829.1 - 0.0013 18.4 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EME79829.1 - 0.083 12.2 0.7 0.14 11.5 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Eno-Rase_FAD_bd PF07055.7 EME79829.1 - 0.4 10.6 2.8 13 5.7 0.1 3.1 2 1 1 3 3 3 0 Enoyl reductase FAD binding domain DUF2415 PF10313.4 EME79830.1 - 3.9e-15 55.2 0.0 8.4e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EME79830.1 - 0.00011 21.8 0.9 3.3 7.7 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Lgl_C PF08596.5 EME79830.1 - 0.0019 16.7 0.0 0.0062 15.0 0.0 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal PQQ_3 PF13570.1 EME79830.1 - 0.018 15.2 0.4 23 5.4 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Ion_trans PF00520.26 EME79832.1 - 0.063 12.5 0.6 0.1 11.8 0.4 1.3 1 0 0 1 1 1 0 Ion transport protein HSP70 PF00012.15 EME79833.1 - 1.6e-263 875.0 14.1 1.9e-263 874.8 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME79833.1 - 1.9e-12 46.4 3.4 4.2e-11 42.0 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EME79833.1 - 0.00052 19.6 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.1 EME79833.1 - 0.002 17.8 2.1 0.0044 16.7 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) FtsA PF14450.1 EME79833.1 - 0.005 16.6 12.3 0.21 11.4 0.7 4.9 3 3 0 3 3 3 2 Cell division protein FtsA HXXSHH PF07586.6 EME79833.1 - 0.01 14.7 2.6 0.018 13.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Methyltransf_12 PF08242.7 EME79834.1 - 5.1e-07 30.0 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME79834.1 - 9.5e-07 29.3 0.0 2.5e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME79834.1 - 3.8e-06 26.5 0.0 5.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME79834.1 - 6.8e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME79834.1 - 0.00027 21.2 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EME79834.1 - 0.0056 16.2 0.0 0.008 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EME79834.1 - 0.035 13.8 0.0 0.098 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_S17e PF00833.13 EME79835.1 - 8.7e-59 196.6 0.7 1e-58 196.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EME79835.1 - 0.0071 17.0 0.2 0.01 16.5 0.2 1.2 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal SH3_1 PF00018.23 EME79838.1 - 3.2e-23 80.8 0.0 7.5e-11 41.2 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EME79838.1 - 4.1e-15 55.0 0.1 2.6e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EME79838.1 - 1.5e-14 53.7 0.1 4e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.12 EME79838.1 - 9.2e-12 44.2 0.0 2.9e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EME79838.1 - 6.8e-06 25.6 0.7 1.3e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 PB1 domain PAT1 PF09770.4 EME79838.1 - 1.7 6.7 12.5 2.7 6.1 8.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAC3_GANP PF03399.11 EME79839.1 - 5.7e-65 218.6 0.3 7.8e-65 218.2 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EME79839.1 - 1.9e-10 40.6 0.5 4.2e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 EME79840.1 - 6.4e-52 175.9 0.0 8.5e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EME79840.1 - 7.5e-28 96.1 0.0 1.2e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EME79840.1 - 0.00035 20.0 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 EME79840.1 - 0.00067 18.7 3.0 0.00067 18.7 2.1 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 EME79840.1 - 0.0027 17.2 0.1 0.0027 17.2 0.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DZR PF12773.2 EME79840.1 - 1.5 8.6 8.2 0.19 11.6 0.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon GMC_oxred_N PF00732.14 EME79841.1 - 1.1e-31 110.1 0.0 2.3e-31 109.0 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME79841.1 - 2.5e-29 102.4 0.0 7.9e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EME79841.1 - 0.00012 22.0 0.1 0.00035 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME79841.1 - 0.00023 20.1 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME79841.1 - 0.0027 17.6 0.6 0.0057 16.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME79841.1 - 0.0028 16.6 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EME79841.1 - 0.014 14.2 0.4 0.085 11.7 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME79841.1 - 0.039 13.9 0.1 0.96 9.4 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PTCRA PF15028.1 EME79841.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Pre-T-cell antigen receptor HI0933_like PF03486.9 EME79841.1 - 0.067 11.6 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 EME79841.1 - 0.088 12.2 0.2 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MOSC_N PF03476.11 EME79842.1 - 4.1e-15 55.5 0.0 8.5e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EME79842.1 - 5.4e-15 55.0 0.0 9.4e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Chitin_synth_2 PF03142.10 EME79843.1 - 1.2e-285 947.9 0.4 1.7e-285 947.4 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EME79843.1 - 6.1e-16 58.7 3.5 2.5e-15 56.7 2.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EME79843.1 - 6.5e-14 52.2 0.0 3.2e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EME79843.1 - 5.7e-11 42.0 0.0 4e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EME79843.1 - 0.00012 21.4 0.0 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME79843.1 - 0.0056 16.3 0.0 0.067 12.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Aminotran_1_2 PF00155.16 EME79845.1 - 6e-38 130.7 0.0 7.1e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME79845.1 - 0.015 14.4 0.0 0.029 13.4 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Sel1 PF08238.7 EME79846.1 - 2e-27 94.9 37.0 1.4e-05 25.5 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat zf-RING_2 PF13639.1 EME79848.1 - 0.00092 18.9 7.8 0.00092 18.9 5.4 2.4 2 0 0 2 2 2 1 Ring finger domain Tetraspannin PF00335.15 EME79848.1 - 0.0071 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Tetraspanin family zf-RING_5 PF14634.1 EME79848.1 - 0.49 10.1 10.1 0.23 11.2 4.7 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 EME79848.1 - 7.6 6.7 8.4 2 8.5 3.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger Chromo PF00385.19 EME79852.1 - 0.0001 21.8 1.0 0.00034 20.2 0.1 2.2 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SPR1 PF15356.1 EME79852.1 - 1.3 9.4 9.7 4.5 7.6 6.7 1.9 1 1 0 1 1 1 0 Psoriasis susceptibility locus 2 Mucin PF01456.12 EME79854.1 - 1.4 8.6 22.9 3.1 7.5 15.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EME79854.1 - 1.7 6.5 19.1 2.3 6.1 13.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DDE_Tnp_4 PF13359.1 EME79855.1 - 3.5e-08 33.2 0.3 3.9e-08 33.0 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 EME79855.1 - 1.7e-06 28.1 0.2 2.1e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 EME79855.1 - 5.1e-05 22.7 0.0 5.7e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 EME79855.1 - 0.003 17.1 0.2 0.0032 17.0 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain Glyco_hydro_43 PF04616.9 EME79858.1 - 5.2e-22 78.2 0.1 9.8e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.19 EME79860.1 - 4.3e-82 276.0 27.2 4.9e-82 275.8 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79860.1 - 1.1e-18 67.1 12.4 1.1e-18 67.1 8.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily CsgF PF10614.4 EME79861.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 1 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Formyl_trans_N PF00551.14 EME79864.1 - 3.9e-39 134.0 0.2 4.9e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EME79864.1 - 5.3e-12 44.9 0.0 1.4e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EME79864.1 - 9.9e-06 25.1 0.0 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 ACT domain Suf PF05843.9 EME79865.1 - 3.7e-05 23.5 5.5 0.0044 16.7 0.2 3.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EME79865.1 - 3.9e-05 23.9 0.4 14 6.6 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME79865.1 - 6.7e-05 23.4 0.0 0.88 10.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME79865.1 - 0.0066 16.5 0.3 24 5.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME79865.1 - 0.033 14.5 0.0 2 8.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MAP7 PF05672.6 EME79866.1 - 7.3 5.9 63.9 0.048 13.0 32.5 2.1 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Rad60-SLD PF11976.3 EME79867.1 - 0.036 13.7 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CAP PF00188.21 EME79868.1 - 1.3e-20 74.1 2.2 2.6e-20 73.1 1.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FAD_binding_3 PF01494.14 EME79869.1 - 7.5e-29 100.8 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME79869.1 - 5.7e-14 51.7 4.7 6.3e-07 28.6 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EME79869.1 - 1.3e-06 27.1 3.5 1.9e-05 23.3 2.4 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EME79869.1 - 1.7e-06 28.2 0.0 3.4e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME79869.1 - 7.9e-06 25.2 1.5 0.0015 17.6 0.0 3.0 3 1 1 4 4 4 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EME79869.1 - 8.5e-06 26.0 3.4 0.063 13.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME79869.1 - 8.8e-06 25.6 0.4 2.2e-05 24.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME79869.1 - 1.5e-05 24.1 0.9 8.1e-05 21.6 0.6 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EME79869.1 - 2.8e-05 22.9 1.7 0.04 12.5 0.2 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EME79869.1 - 7.9e-05 22.6 0.1 0.00025 20.9 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME79869.1 - 0.00052 19.1 0.1 0.00086 18.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EME79869.1 - 0.001 18.7 0.6 0.0018 17.9 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EME79869.1 - 0.0013 17.9 0.2 0.002 17.2 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME79869.1 - 0.0015 17.4 4.6 0.0027 16.6 3.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EME79869.1 - 0.0067 15.3 0.5 0.011 14.6 0.4 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 EME79869.1 - 0.017 13.9 0.0 0.3 9.8 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Rossmann-like PF10727.4 EME79869.1 - 0.036 13.7 0.6 0.17 11.6 0.1 2.2 2 1 0 2 2 2 0 Rossmann-like domain MFS_1 PF07690.11 EME79870.1 - 3.8e-23 81.7 34.8 4.6e-23 81.5 24.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME79870.1 - 3.4e-10 39.0 10.6 3.4e-10 39.0 7.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.17 EME79872.1 - 4.8e-51 173.7 0.0 1.4e-50 172.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Taxilin PF09728.4 EME79873.1 - 4.2e-79 265.8 60.0 5.6e-79 265.4 41.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Speriolin_N PF15058.1 EME79873.1 - 6.1 6.6 12.3 0.21 11.4 0.2 3.1 2 2 1 3 3 3 0 Speriolin N terminus M16C_assoc PF08367.6 EME79874.1 - 4.6e-60 202.5 0.0 8.4e-60 201.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EME79874.1 - 7.9e-27 94.1 0.3 1.2e-15 57.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME79874.1 - 7e-10 38.8 0.0 6.3e-08 32.5 0.0 2.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) MIT PF04212.13 EME79874.1 - 0.31 10.9 4.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Erv26 PF04148.8 EME79875.1 - 6.6e-81 270.7 0.3 7.3e-81 270.5 0.2 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.15 EME79875.1 - 0.011 15.2 0.8 0.017 14.6 0.3 1.5 1 1 0 1 1 1 0 Cytochrome C assembly protein QueT PF06177.6 EME79875.1 - 0.055 13.4 0.6 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 QueT transporter WBS_methylT PF12589.3 EME79876.1 - 1.7e-16 60.4 7.2 3.5e-16 59.4 5.0 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EME79876.1 - 2.1e-11 44.1 0.1 7.2e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME79876.1 - 4e-09 36.7 0.0 1.1e-08 35.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME79876.1 - 4.1e-07 29.6 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME79876.1 - 1.3e-05 25.5 0.0 4.9e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME79876.1 - 3.8e-05 23.3 0.0 8.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EME79876.1 - 0.00014 22.4 0.0 0.00028 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME79876.1 - 0.0002 21.0 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME79876.1 - 0.0062 15.6 0.0 0.023 13.7 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EME79876.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EME79876.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EME79876.1 - 0.12 11.6 0.7 5.3 6.3 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase small domain SAM_2 PF07647.12 EME79878.1 - 1.9e-06 27.6 0.2 3.8e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EME79878.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.25 EME79878.1 - 0.00066 19.7 0.3 0.0017 18.4 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EME79878.1 - 0.02 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fungal_trans_2 PF11951.3 EME79879.1 - 7.4e-75 251.9 0.1 1e-74 251.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME79879.1 - 1.8e-06 27.7 8.8 3.8e-06 26.7 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRM PF02005.11 EME79879.1 - 0.14 11.0 0.8 0.49 9.2 0.8 1.6 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase HTH_37 PF13744.1 EME79879.1 - 1.4 8.8 4.2 3.1 7.6 2.5 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Virulence_fact PF13769.1 EME79880.1 - 0.093 12.6 0.1 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Virulence factor FimP PF09766.4 EME79881.1 - 4.7e-23 81.8 4.0 5.5e-23 81.6 2.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EME79881.1 - 0.044 13.7 0.5 0.044 13.7 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Response_reg PF00072.19 EME79882.1 - 1.5e-20 73.2 0.1 4.3e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EME79882.1 - 1.4e-19 69.8 0.0 2.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME79882.1 - 6.2e-06 26.1 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.1 EME79882.1 - 0.0021 17.7 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.1 EME79882.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EME79882.1 - 0.081 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HSL_N PF06350.7 EME79882.1 - 0.11 11.6 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus FeoC PF09012.5 EME79882.1 - 0.18 11.5 0.3 4.2 7.1 0.0 2.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator MFS_1 PF07690.11 EME79884.1 - 2e-39 135.3 51.7 4.4e-39 134.1 35.8 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME79884.1 - 5.8e-15 54.5 25.4 7.7e-15 54.1 17.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EME79884.1 - 1.5e-05 23.8 17.1 1.5e-05 23.8 11.9 4.0 3 2 1 4 4 4 2 Sugar (and other) transporter Arrestin_N PF00339.24 EME79885.1 - 1.1e-16 60.9 0.0 2.2e-14 53.5 0.0 3.2 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EME79885.1 - 3.8e-05 23.8 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain GST_N_2 PF13409.1 EME79886.1 - 1.7e-06 27.9 0.0 5e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME79886.1 - 2.1e-05 24.4 0.0 5.3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME79886.1 - 4.7e-05 23.2 0.0 7.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME79886.1 - 8.7e-05 22.6 0.0 0.00027 21.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME79886.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME79886.1 - 0.031 14.7 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CPSase_L_D2 PF02786.12 EME79887.1 - 9.4e-80 266.8 0.0 1.5e-79 266.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EME79887.1 - 6.1e-66 221.5 0.0 9.9e-66 220.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EME79887.1 - 1.7e-35 121.4 0.0 3.8e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME79887.1 - 1.1e-30 105.8 0.0 3.4e-30 104.1 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EME79887.1 - 8.5e-28 97.6 0.0 1.6e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EME79887.1 - 2.2e-18 65.6 3.0 4.5e-18 64.6 2.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EME79887.1 - 1.4e-17 63.4 0.0 1.3e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EME79887.1 - 2.7e-16 59.8 0.0 5.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EME79887.1 - 4.7e-10 38.9 0.3 5e-06 26.0 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EME79887.1 - 2.9e-08 33.3 0.0 4.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EME79887.1 - 0.0001 21.8 0.0 0.00084 18.8 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EME79887.1 - 0.00029 20.2 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EME79887.1 - 0.00029 21.1 0.0 0.028 14.7 0.0 3.2 2 1 1 3 3 3 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 EME79887.1 - 0.00074 19.4 0.0 0.0026 17.6 0.0 2.0 2 0 0 2 2 1 1 ATP-grasp domain HlyD_2 PF12700.2 EME79887.1 - 0.0059 15.8 0.1 0.87 8.6 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 EME79887.1 - 0.0066 15.6 0.2 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 EME79887.1 - 0.0094 15.6 0.4 0.026 14.2 0.3 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 EME79887.1 - 0.012 15.3 0.1 0.055 13.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 EME79887.1 - 0.013 15.2 0.2 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD PF00529.15 EME79887.1 - 0.098 11.9 0.7 0.24 10.6 0.0 2.0 3 0 0 3 3 3 0 HlyD family secretion protein Iso_dh PF00180.15 EME79888.1 - 1e-83 281.1 0.0 1.2e-83 280.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3511 PF12023.3 EME79889.1 - 1.9e-07 30.2 4.2 0.68 9.3 0.0 6.1 5 1 1 6 6 6 4 Domain of unknown function (DUF3511) Cm_res_leader PF08077.6 EME79889.1 - 0.23 11.2 15.3 75 3.3 0.0 6.2 6 0 0 6 6 6 0 Chloramphenicol resistance gene leader peptide SNase PF00565.12 EME79889.1 - 7.3 6.9 6.4 31 4.8 0.2 3.0 3 0 0 3 3 3 0 Staphylococcal nuclease homologue Zds_C PF08632.5 EME79890.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term UCH PF00443.24 EME79891.1 - 2.8e-23 82.3 0.0 3.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EME79891.1 - 5.9e-10 39.1 0.1 9.8e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EME79891.1 - 0.0041 16.5 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_fiss_reg PF05308.6 EME79891.1 - 0.2 11.0 4.2 0.33 10.2 2.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator TRP_N PF14558.1 EME79892.1 - 2.2e-20 73.1 0.7 2.4e-20 73.0 0.5 1.0 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EME79892.1 - 0.081 13.1 0.0 0.097 12.9 0.0 1.1 1 0 0 1 1 1 0 ML domain Autotrns_rpt PF12951.2 EME79892.1 - 0.12 12.0 1.2 0.25 11.0 0.9 1.6 1 0 0 1 1 1 0 Autotransporter-associated beta strand repeat DSBA PF01323.15 EME79893.1 - 2e-23 82.9 0.0 2.2e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain TPR_11 PF13414.1 EME79894.1 - 8.4e-10 38.1 0.5 8.8e-08 31.6 0.3 2.5 2 0 0 2 2 2 1 TPR repeat F-box PF00646.28 EME79894.1 - 3.4e-07 29.7 0.0 7.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.12 EME79894.1 - 3.4e-07 29.6 1.0 0.017 14.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.2 EME79894.1 - 5.2e-07 29.2 0.3 1.2e-06 28.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.23 EME79894.1 - 0.0004 19.8 1.1 0.39 10.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_6 PF13516.1 EME79894.1 - 0.0012 18.6 0.1 0.097 12.7 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich repeat TPR_16 PF13432.1 EME79894.1 - 0.0025 18.4 1.7 0.037 14.7 1.1 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME79894.1 - 0.0026 17.6 1.3 1.4 8.9 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME79894.1 - 0.0034 17.6 0.9 0.51 10.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat LRR_4 PF12799.2 EME79894.1 - 0.0048 16.5 5.2 2.1 8.0 0.0 4.7 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) TPR_14 PF13428.1 EME79894.1 - 0.023 15.3 0.4 4 8.3 0.0 3.3 2 1 1 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EME79894.1 - 0.053 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_8 PF13855.1 EME79894.1 - 0.11 12.2 0.9 4.4 7.1 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat Acetyltransf_1 PF00583.19 EME79895.1 - 4.9e-12 45.7 0.0 7.5e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME79895.1 - 4.2e-07 30.0 0.0 8.2e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME79895.1 - 5.5e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EME79895.1 - 3e-05 23.9 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME79895.1 - 0.0002 21.4 0.0 0.0032 17.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME79895.1 - 0.0015 18.6 0.0 0.0036 17.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Grp1_Fun34_YaaH PF01184.14 EME79897.1 - 9.6e-27 93.6 15.2 1.3e-26 93.2 10.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Abhydrolase_5 PF12695.2 EME79898.1 - 1.1e-13 51.1 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fic PF02661.13 EME79899.1 - 6.7e-20 71.6 0.1 4.9e-19 68.8 0.0 2.2 2 0 0 2 2 2 1 Fic/DOC family Metallophos PF00149.23 EME79900.1 - 2.9e-12 46.3 0.9 1.2e-11 44.4 0.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME79900.1 - 3.9e-12 46.2 0.0 5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.20 EME79902.1 - 1.3e-67 227.6 0.0 2.2e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME79902.1 - 2.3e-40 138.3 0.0 3.5e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME79902.1 - 6e-10 38.5 0.0 2.5e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME79902.1 - 0.0011 18.8 6.1 0.12 12.1 0.1 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EME79902.1 - 0.0019 17.3 0.1 0.0092 15.0 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EME79902.1 - 0.17 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EME79902.1 - 0.22 11.0 0.0 0.45 10.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Clathrin PF00637.15 EME79903.1 - 1.5e-201 660.0 31.9 6e-33 113.4 1.9 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EME79903.1 - 2.3e-30 104.2 2.8 6.5e-30 102.8 0.7 2.9 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EME79903.1 - 1.2e-29 100.4 1.1 1.3e-05 25.1 0.0 7.3 7 0 0 7 7 7 6 Clathrin propeller repeat Vps39_1 PF10366.4 EME79903.1 - 2.5e-05 24.2 7.5 2.5 8.1 0.0 6.0 4 1 1 5 5 5 2 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.9 EME79903.1 - 0.00018 20.4 4.5 0.05 12.4 0.3 4.1 5 0 0 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.1 EME79903.1 - 0.00018 21.0 4.3 5.2 7.1 0.0 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF1720 PF08226.6 EME79903.1 - 0.00069 19.6 5.0 0.00069 19.6 3.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1720) Clathrin-link PF09268.5 EME79903.1 - 0.0015 17.5 0.2 0.0043 16.0 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_14 PF13428.1 EME79903.1 - 0.0023 18.4 16.0 8.2 7.3 0.0 10.1 13 0 0 13 13 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME79903.1 - 0.0059 16.2 1.4 3.1 7.7 0.0 4.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME79903.1 - 0.019 14.8 5.5 0.73 9.8 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2191 PF09957.4 EME79903.1 - 0.035 13.9 0.0 0.23 11.3 0.0 2.4 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_12 PF13424.1 EME79903.1 - 0.047 13.6 8.3 0.98 9.4 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME79903.1 - 0.43 10.9 10.8 1.9 8.8 0.1 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME79903.1 - 4.3 7.0 11.1 2.9 7.6 0.1 5.3 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.23 EME79903.1 - 9.5 6.0 10.4 0.95 9.1 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat 14-3-3 PF00244.15 EME79904.1 - 1.8e-114 380.7 0.4 2.1e-114 380.4 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 EME79904.1 - 0.07 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) TPR_12 PF13424.1 EME79904.1 - 0.13 12.1 2.4 5.9 6.9 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat GST_N PF02798.15 EME79907.1 - 1.9e-09 37.5 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME79907.1 - 3.2e-09 36.5 0.0 5.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME79907.1 - 4.7e-08 32.9 0.0 7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME79907.1 - 2.3e-06 27.7 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME79907.1 - 4e-06 26.7 0.0 7.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME79907.1 - 2.6e-05 24.5 0.0 4.9e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain G-patch_2 PF12656.2 EME79908.1 - 2.3e-24 85.0 0.1 2.3e-24 85.0 0.1 3.5 3 2 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EME79908.1 - 1.1e-05 25.1 1.9 2.9e-05 23.7 1.3 1.9 1 0 0 1 1 1 1 G-patch domain zf-C2H2 PF00096.21 EME79909.1 - 1.2e-12 47.3 14.6 4.6e-07 29.7 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME79909.1 - 1.3e-10 40.7 11.2 0.0001 22.3 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME79909.1 - 1.5e-06 28.1 14.5 3.3e-05 23.9 4.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EME79909.1 - 1e-05 25.4 7.0 0.0038 17.3 1.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME79909.1 - 4.6e-05 23.4 6.1 0.0035 17.4 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EME79909.1 - 0.00011 21.9 0.8 0.00011 21.9 0.6 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger LIM PF00412.17 EME79909.1 - 0.11 12.5 3.9 0.25 11.4 2.7 1.6 1 0 0 1 1 1 0 LIM domain Cation_efflux PF01545.16 EME79911.1 - 0.12 11.3 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family Zn_Tnp_IS1 PF03811.8 EME79911.1 - 1.5 8.3 6.9 6.6 6.3 2.2 2.2 2 0 0 2 2 2 0 InsA N-terminal domain Glyco_transf_8 PF01501.15 EME79913.1 - 2.7e-16 59.6 0.2 5e-16 58.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 APG9 PF04109.11 EME79914.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 TUG-UBL1 PF11470.3 EME79916.1 - 4.6e-23 80.9 0.3 1.2e-22 79.5 0.2 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EME79916.1 - 7.3e-06 25.9 0.1 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 1 UBX domain RBD PF02196.10 EME79916.1 - 1.4e-05 24.7 0.0 3.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain Rad60-SLD PF11976.3 EME79916.1 - 9e-05 22.0 0.1 0.28 10.8 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.18 EME79916.1 - 0.0093 16.4 0.2 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain UN_NPL4 PF11543.3 EME79916.1 - 0.068 13.4 0.0 0.9 9.8 0.0 2.5 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 YukD PF08817.5 EME79916.1 - 0.13 12.8 0.9 2.2 8.8 0.0 3.3 5 0 0 5 5 5 0 WXG100 protein secretion system (Wss), protein YukD PITH PF06201.8 EME79917.1 - 3.3e-44 150.3 0.0 4.7e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EME79917.1 - 4e-28 97.1 0.0 6.8e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME79917.1 - 5.3e-07 29.6 0.0 0.00016 21.7 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EME79917.1 - 3.6e-06 27.1 0.1 1.8e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EME79917.1 - 0.0046 16.5 0.1 0.065 12.7 0.1 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EME79917.1 - 0.0054 16.3 0.0 0.0097 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME79917.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 EME79917.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family HypA PF01155.14 EME79918.1 - 0.013 15.2 1.1 0.023 14.3 0.3 1.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2072 PF09845.4 EME79918.1 - 0.05 13.5 1.5 0.064 13.1 0.5 1.6 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF1272 PF06906.6 EME79918.1 - 0.052 13.4 0.9 0.1 12.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn-ribbon_8 PF09723.5 EME79918.1 - 0.34 10.9 5.0 0.72 9.8 3.0 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EME79918.1 - 0.42 10.4 5.0 3.5 7.5 1.8 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EME79918.1 - 0.51 9.9 4.6 2.6 7.6 0.2 3.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EME79918.1 - 0.58 9.8 4.5 2.9 7.6 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain FAD_binding_3 PF01494.14 EME79919.1 - 2.8e-19 69.4 0.1 5.4e-12 45.4 0.0 2.9 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME79919.1 - 9.7e-05 22.3 1.9 0.00013 21.8 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME79919.1 - 0.0018 17.2 1.3 0.0035 16.2 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME79919.1 - 0.03 14.1 0.1 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME79919.1 - 0.035 12.9 0.6 0.068 12.0 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EME79919.1 - 0.036 12.6 0.9 0.051 12.2 0.2 1.4 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EME79919.1 - 0.038 13.8 0.1 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 ThiF family Amino_oxidase PF01593.19 EME79919.1 - 0.15 11.0 0.1 3.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 EME79919.1 - 0.17 11.2 0.4 0.34 10.2 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EME79919.1 - 0.2 10.0 0.2 0.33 9.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EME79919.1 - 0.29 10.8 1.5 0.63 9.7 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding MDM31_MDM32 PF08118.6 EME79920.1 - 3.2e-180 599.9 1.6 3.8e-180 599.6 1.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Shadoo PF14999.1 EME79920.1 - 0.028 14.2 0.4 0.069 12.9 0.3 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_L36e PF01158.13 EME79921.1 - 5.6e-41 138.4 6.0 6.4e-41 138.3 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EME79921.1 - 0.081 12.0 0.1 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 LemA family PBS_linker_poly PF00427.16 EME79921.1 - 0.12 12.0 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide BTB PF00651.26 EME79922.1 - 5e-18 65.1 5.1 1.7e-12 47.2 1.3 2.8 2 1 0 2 2 2 2 BTB/POZ domain zf-C4pol PF14260.1 EME79922.1 - 0.31 11.0 6.0 0.079 12.9 1.4 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Fer2_3 PF13085.1 EME79923.1 - 3.6e-32 110.4 0.0 5.8e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EME79923.1 - 6.8e-10 39.1 7.3 6.8e-10 39.1 5.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EME79923.1 - 9e-09 35.2 5.4 9e-09 35.2 3.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EME79923.1 - 0.00026 21.3 2.4 0.00026 21.3 1.7 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EME79923.1 - 0.0004 20.5 4.0 0.026 14.7 0.5 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EME79923.1 - 0.0023 17.6 6.0 0.0023 17.6 4.2 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EME79923.1 - 0.0082 15.8 0.4 0.0082 15.8 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EME79923.1 - 0.2 12.0 12.4 0.046 14.1 4.9 2.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EME79923.1 - 1.4 9.5 5.6 1 9.9 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain HAD PF12710.2 EME79924.1 - 3.5e-06 27.3 0.1 2.1e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase EF1G PF00647.14 EME79924.1 - 0.099 12.3 0.7 0.22 11.2 0.2 1.8 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain 7TMR-DISM_7TM PF07695.6 EME79925.1 - 0.0062 16.2 1.1 0.0089 15.7 0.8 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling VIT1 PF01988.14 EME79925.1 - 0.0067 15.9 0.2 0.0077 15.7 0.1 1.1 1 0 0 1 1 1 1 VIT family E1-E2_ATPase PF00122.15 EME79925.1 - 0.013 14.5 0.8 0.017 14.1 0.6 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Imm42 PF15601.1 EME79925.1 - 0.054 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 42 SinI PF08671.5 EME79925.1 - 0.085 12.3 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Anti-repressor SinI GPI2 PF06432.6 EME79925.1 - 0.14 11.5 4.7 0.18 11.1 3.3 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase SdpI PF13630.1 EME79925.1 - 0.65 9.7 4.3 0.24 11.1 1.3 1.5 2 0 0 2 2 2 0 SdpI/YhfL protein family DEAD PF00270.24 EME79929.1 - 1.3e-46 158.1 0.0 2.1e-45 154.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME79929.1 - 1e-27 95.7 0.0 2e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME79929.1 - 0.02 14.7 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EME79929.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EME79929.1 - 0.17 10.2 0.0 0.34 9.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) eIF3_subunit PF08597.5 EME79930.1 - 2.1e-66 224.0 30.1 2.3e-66 223.8 20.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PDDEXK_4 PF14281.1 EME79930.1 - 0.021 14.6 0.2 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Imm42 PF15601.1 EME79930.1 - 0.092 12.1 2.1 0.85 9.0 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 42 TMV_coat PF00721.16 EME79930.1 - 0.71 9.7 8.1 0.93 9.4 0.4 2.5 2 0 0 2 2 2 0 Virus coat protein (TMV like) ApoLp-III PF07464.6 EME79931.1 - 0.037 14.0 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4148 PF13663.1 EME79931.1 - 0.068 13.0 0.7 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Cpn60_TCP1 PF00118.19 EME79932.1 - 5.8e-128 427.5 6.7 6.9e-128 427.3 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 EME79932.1 - 0.13 12.5 1.0 1.6 8.9 0.1 3.1 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain Lactonase PF10282.4 EME79933.1 - 1.7e-12 47.1 0.0 6.2e-12 45.2 0.0 2.2 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 EME79933.1 - 0.099 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Arylesterase WW PF00397.21 EME79935.1 - 4.7e-09 35.9 0.6 1.4e-08 34.4 0.4 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EME79935.1 - 0.0095 14.5 0.6 0.015 13.8 0.4 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase TFIIA PF03153.8 EME79936.1 - 8.8e-07 29.1 14.0 8.8e-07 29.1 9.7 2.7 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit NACHT PF05729.7 EME79938.1 - 4.8e-15 55.6 0.6 1.1e-14 54.4 0.4 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME79938.1 - 3.5e-06 27.1 0.0 6.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME79938.1 - 4.4e-05 23.6 0.0 8.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME79938.1 - 0.0036 16.4 0.0 0.0073 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EME79938.1 - 0.0043 16.7 0.0 0.0055 16.4 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EME79938.1 - 0.0052 16.2 0.0 0.031 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain NB-ARC PF00931.17 EME79938.1 - 0.0094 14.8 0.0 0.021 13.7 0.0 1.4 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 EME79938.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EME79938.1 - 0.029 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EME79938.1 - 0.044 14.0 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 EME79938.1 - 0.05 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EME79938.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EME79938.1 - 0.089 12.3 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EME79938.1 - 0.09 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EME79938.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EME79938.1 - 0.22 12.3 1.1 0.47 11.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain ATP11 PF06644.6 EME79939.1 - 6.8e-84 281.5 0.3 8.1e-84 281.2 0.2 1.1 1 0 0 1 1 1 1 ATP11 protein 4HBT_3 PF13622.1 EME79939.1 - 0.0028 17.4 0.6 0.0041 16.9 0.4 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MCPVI PF02993.9 EME79939.1 - 2.5 8.1 6.3 3.8 7.5 4.4 1.2 1 0 0 1 1 1 0 Minor capsid protein VI AIG2_2 PF13772.1 EME79940.1 - 6.7e-05 22.9 0.0 0.00023 21.2 0.0 1.8 2 0 0 2 2 2 1 AIG2-like family DUF550 PF04447.7 EME79944.1 - 0.02 14.4 0.2 0.29 10.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF550) FCH PF00611.18 EME79946.1 - 4.3e-17 62.0 0.0 1.1e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EME79946.1 - 5.4e-16 58.5 0.0 1.3e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 EME79946.1 - 1.8e-11 43.6 0.0 3.5e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glyco_hydro_38 PF01074.17 EME79947.1 - 0.35 10.0 4.5 4.5 6.4 0.0 2.7 3 0 0 3 3 3 0 Glycosyl hydrolases family 38 N-terminal domain UPF0561 PF10573.4 EME79947.1 - 1.1 9.0 10.9 5.2 6.9 2.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 GlgS PF08971.6 EME79948.1 - 0.08 12.8 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthesis protein YTH PF04146.10 EME79949.1 - 1.4e-54 183.4 0.0 2.1e-54 182.9 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EME79949.1 - 4.3e-06 26.2 0.0 7.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME79949.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME79949.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HisG PF01634.13 EME79951.1 - 5.5e-52 175.6 0.1 8e-52 175.0 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EME79951.1 - 7e-28 96.3 0.2 1.4e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EME79951.1 - 0.016 14.7 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 NMT1/THI5 like Methyltrans_RNA PF04452.9 EME79951.1 - 0.042 12.9 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Ribosomal_S28e PF01200.13 EME79952.1 - 6.6e-33 112.2 2.7 7.1e-33 112.1 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e SET PF00856.23 EME79953.1 - 0.00053 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 SET domain HypA PF01155.14 EME79953.1 - 0.12 12.1 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GMC_oxred_N PF00732.14 EME79954.1 - 4.4e-34 117.9 0.0 6.5e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME79954.1 - 5.9e-16 59.0 0.0 2.3e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME79954.1 - 2.5e-08 33.2 0.1 1.2e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME79954.1 - 3.6e-07 29.4 0.0 0.00058 18.8 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EME79954.1 - 9.9e-06 24.2 0.4 6.3e-05 21.6 0.0 2.3 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.14 EME79954.1 - 2.1e-05 23.7 0.1 3.5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME79954.1 - 4.6e-05 23.3 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME79954.1 - 5e-05 22.5 0.2 0.00078 18.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME79954.1 - 8.1e-05 21.8 0.0 0.00043 19.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EME79954.1 - 0.0001 22.2 0.0 0.0003 20.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EME79954.1 - 0.0026 16.6 0.1 0.0082 15.0 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME79954.1 - 0.0057 16.7 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EndoU_bacteria PF14436.1 EME79954.1 - 0.019 14.7 0.8 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial EndoU nuclease Lycopene_cycl PF05834.7 EME79954.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2236 PF09995.4 EME79956.1 - 9.8e-13 47.9 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Zn_clus PF00172.13 EME79957.1 - 0.0035 17.1 1.0 0.0079 16.0 0.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRS1 PF04939.7 EME79958.1 - 6.9e-43 145.9 4.3 7.6e-43 145.8 3.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) IBR PF01485.16 EME79959.1 - 3e-10 39.8 24.9 3.2e-06 26.9 1.7 5.2 4 2 0 4 4 4 2 IBR domain HflK_N PF12221.3 EME79959.1 - 0.0099 15.5 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial membrane protein N terminal Furin-like PF00757.15 EME79961.1 - 0.0098 15.5 1.5 0.0098 15.5 1.1 2.8 1 1 2 3 3 3 1 Furin-like cysteine rich region DUF3708 PF12501.3 EME79961.1 - 0.044 13.6 0.6 0.072 12.9 0.4 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter tRNA-synt_2e PF02091.10 EME79961.1 - 0.044 12.8 0.7 0.085 11.9 0.2 1.7 1 1 1 2 2 2 0 Glycyl-tRNA synthetase alpha subunit NUC205 PF08168.6 EME79961.1 - 0.79 9.1 3.8 15 5.0 0.1 2.4 2 0 0 2 2 2 0 NUC205 domain Fcf1 PF04900.7 EME79962.1 - 2.7e-38 130.1 2.4 2.8e-38 130.0 0.2 2.1 3 0 0 3 3 3 1 Fcf1 MutS_V PF00488.16 EME79964.1 - 1.7e-90 302.5 0.1 2.7e-90 301.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME79964.1 - 2.6e-36 125.3 2.6 2.6e-36 125.3 1.8 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EME79964.1 - 7.6e-27 93.5 0.0 1.8e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EME79964.1 - 2.1e-08 34.3 0.0 8.1e-08 32.4 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EME79964.1 - 4e-05 23.7 0.1 0.00015 21.8 0.1 2.0 1 0 0 1 1 1 1 MutS family domain IV DUF3328 PF11807.3 EME79969.1 - 8.6e-24 84.4 2.6 1.1e-23 84.0 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Formyl_trans_N PF00551.14 EME79974.1 - 1.9e-37 128.5 0.0 2.6e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase zf-C2H2 PF00096.21 EME79976.1 - 1.2e-06 28.4 20.4 0.0012 19.0 0.5 3.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME79976.1 - 5.2e-05 23.2 11.0 0.058 13.7 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EME79976.1 - 0.018 14.9 0.9 0.7 9.8 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.7 EME79976.1 - 0.039 13.9 4.5 3 7.9 0.3 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain RCR PF12273.3 EME79977.1 - 1.4e-14 54.7 10.9 9.5e-14 52.0 7.6 2.0 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.13 EME79977.1 - 0.012 13.9 0.2 0.015 13.5 0.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF1469 PF07332.6 EME79977.1 - 0.059 13.1 0.6 0.081 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF1191 PF06697.7 EME79977.1 - 0.063 12.0 0.8 0.086 11.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Tetraspannin PF00335.15 EME79977.1 - 0.075 12.2 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family SKG6 PF08693.5 EME79977.1 - 0.11 11.8 5.1 0.16 11.2 3.5 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1206 PF06724.6 EME79977.1 - 0.12 12.1 1.1 0.23 11.2 0.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) SIT PF15330.1 EME79977.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4083 PF13314.1 EME79977.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) P12 PF12669.2 EME79977.1 - 0.21 11.8 0.6 0.31 11.2 0.4 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family Hum_adeno_E3A PF05393.6 EME79977.1 - 0.32 10.6 0.2 0.32 10.6 0.1 1.6 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Peptidase_M1 PF01433.15 EME79978.1 - 6.8e-122 407.3 0.0 8.5e-122 406.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EME79978.1 - 7e-45 153.6 0.0 1.1e-44 153.0 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EME79978.1 - 9.3e-21 74.1 0.2 1.6e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily OPT PF03169.10 EME79979.1 - 5.1e-143 477.7 37.9 5.9e-143 477.5 26.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Methyltransf_31 PF13847.1 EME79980.1 - 2.5e-11 43.4 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME79980.1 - 4.3e-10 40.1 0.0 6.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME79980.1 - 1.4e-07 31.9 0.0 2.6e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME79980.1 - 0.00012 22.0 0.0 0.00062 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME79980.1 - 0.00017 21.8 0.0 0.0003 21.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME79980.1 - 0.0024 18.3 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME79980.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.18 EME79982.1 - 1.5e-08 33.9 0.1 1.7e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME79982.1 - 1.3e-07 31.1 0.0 1.6e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EME79982.1 - 0.022 14.4 0.0 0.023 14.4 0.0 1.0 1 0 0 1 1 1 0 Telomere stability and silencing FERM_N PF09379.5 EME79982.1 - 0.065 13.2 0.3 0.16 12.0 0.0 1.7 1 1 1 2 2 2 0 FERM N-terminal domain MFS_1 PF07690.11 EME79983.1 - 2.3e-28 98.9 30.4 4.3e-28 98.0 21.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME79983.1 - 4.7e-09 35.3 9.0 4.7e-09 35.3 6.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter CAP PF00188.21 EME79984.1 - 1.2e-23 83.9 5.9 1.4e-23 83.7 4.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Stanniocalcin PF03298.8 EME79984.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Stanniocalcin family MPC PF03650.8 EME79985.1 - 1.1e-36 125.3 0.0 1.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CsbD PF05532.7 EME79985.1 - 0.22 11.2 11.9 0.12 12.0 1.0 2.2 2 0 0 2 2 2 0 CsbD-like Sugar_tr PF00083.19 EME79987.1 - 3.5e-96 322.5 19.7 4.2e-96 322.2 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME79987.1 - 6.1e-20 71.2 34.3 5e-15 55.0 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.1 EME79988.1 - 1.8e-19 70.3 0.0 3.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME79988.1 - 5.9e-14 52.1 0.0 9.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like_2 PF13013.1 EME79989.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain Adaptin_N PF01602.15 EME79990.1 - 3.6e-80 269.7 0.0 6.2e-80 269.0 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EME79990.1 - 8.3e-06 26.0 11.2 0.025 14.8 0.8 4.8 4 1 1 5 5 4 2 HEAT repeats Cnd1 PF12717.2 EME79990.1 - 0.00087 19.1 1.5 0.89 9.3 0.2 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EME79990.1 - 0.05 13.6 0.2 12 6.2 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EME79990.1 - 0.31 11.5 7.6 15 6.1 0.2 5.5 4 2 2 6 6 6 0 HEAT-like repeat Velvet PF11754.3 EME79992.1 - 1.2e-67 227.4 0.0 1.4e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Fumerase PF05681.9 EME79993.1 - 0.15 11.1 0.6 0.19 10.8 0.4 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Peptidase_M16_C PF05193.16 EME79994.1 - 8.4e-20 71.2 0.0 3.2e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME79994.1 - 8e-07 28.9 0.3 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Herpes_ICP4_C PF03585.9 EME79994.1 - 0.097 11.3 0.1 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region ubiquitin PF00240.18 EME79996.1 - 4.1e-08 32.5 0.0 8.7e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME79996.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like AA_permease PF00324.16 EME79997.1 - 1.3e-49 168.8 9.5 1.5e-49 168.6 6.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME79997.1 - 1.4e-09 36.9 9.2 1.7e-09 36.7 6.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 EME79997.1 - 0.039 13.3 4.1 0.35 10.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) TMEM173 PF15009.1 EME79997.1 - 0.13 11.0 0.5 0.18 10.5 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 PrgI PF12666.2 EME79997.1 - 4.8 7.4 6.2 3.8 7.7 0.4 2.6 2 1 0 2 2 2 0 PrgI family protein MFS_1 PF07690.11 EME79998.1 - 0.0038 16.0 0.3 0.0038 16.0 0.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.18 EME80001.1 - 1.9e-30 105.8 0.0 5.9e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EME80001.1 - 2.6e-15 55.9 0.0 2.1e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EME80001.1 - 7.7e-07 28.9 3.9 2.2e-06 27.4 0.1 3.0 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EME80001.1 - 0.0065 16.4 0.2 0.061 13.2 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EME80001.1 - 0.016 15.6 0.0 0.059 13.8 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein DUF2179 PF10035.4 EME80001.1 - 0.079 12.5 0.1 0.29 10.7 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) AAA_16 PF13191.1 EME80001.1 - 0.099 12.6 0.6 3.5 7.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain WD40 PF00400.27 EME80004.1 - 2.4e-35 119.1 6.7 1.9e-07 30.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EME80004.1 - 0.016 13.3 0.7 2 6.4 0.3 3.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EME80004.1 - 0.068 13.4 0.4 26 5.2 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain GST_N_3 PF13417.1 EME80005.1 - 2.9e-18 65.8 0.0 5.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME80005.1 - 6.6e-15 55.0 0.0 1.5e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME80005.1 - 2e-11 43.7 0.0 5.4e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME80005.1 - 5.2e-08 32.7 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME80005.1 - 1e-05 25.9 0.1 2.3e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME80005.1 - 1.1e-05 25.1 0.2 2.3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phage_Mu_Gam PF07352.7 EME80005.1 - 0.0055 16.2 0.1 0.009 15.5 0.1 1.3 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Moulting_cycle PF04870.11 EME80006.1 - 0.0085 15.2 0.2 0.012 14.7 0.2 1.2 1 0 0 1 1 1 1 Moulting cycle PriCT_1 PF08708.6 EME80006.1 - 0.014 15.1 0.0 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) DUF1395 PF07160.7 EME80006.1 - 0.028 13.9 0.5 0.035 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) IncA PF04156.9 EME80006.1 - 0.037 13.6 2.2 0.044 13.3 1.5 1.3 1 0 0 1 1 1 0 IncA protein Med9 PF07544.8 EME80006.1 - 0.74 9.5 5.6 11 5.8 0.0 3.5 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APG5 PF04106.7 EME80008.1 - 2.3e-59 200.2 0.0 2.8e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 TPR_19 PF14559.1 EME80009.1 - 5.3e-11 42.6 0.2 9.4e-08 32.2 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME80009.1 - 6e-11 41.9 0.4 9.2e-05 22.7 0.0 4.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME80009.1 - 7.8e-11 41.4 0.2 5.7e-06 25.8 0.0 3.0 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EME80009.1 - 5.9e-10 38.3 0.3 2.3e-06 26.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME80009.1 - 6e-10 38.2 0.0 5.2e-07 29.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME80009.1 - 2.4e-08 34.4 1.9 0.002 18.7 0.0 3.8 2 1 3 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EME80009.1 - 1.6e-07 30.5 0.4 0.00026 20.5 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME80009.1 - 6.6e-07 29.0 0.0 3.6e-05 23.5 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME80009.1 - 3.6e-06 27.0 0.2 0.9 10.1 0.0 4.3 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME80009.1 - 4.2e-06 26.5 0.0 0.00082 19.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME80009.1 - 2.5e-05 24.1 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EME80009.1 - 3e-05 23.4 0.0 0.0014 18.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 EME80009.1 - 0.00019 20.3 0.1 0.00026 19.8 0.1 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 EME80009.1 - 0.00049 20.1 0.0 1 9.4 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EME80009.1 - 0.00072 19.6 0.0 0.0099 16.0 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EME80009.1 - 0.003 16.6 0.9 0.0055 15.8 0.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat NARP1 PF12569.3 EME80009.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DnaJ PF00226.26 EME80010.1 - 4.1e-19 68.0 4.4 4.1e-19 68.0 3.0 1.5 2 0 0 2 2 2 1 DnaJ domain Bacteriocin_IIc PF10439.4 EME80010.1 - 0.032 14.3 2.3 0.054 13.6 1.6 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.8 EME80010.1 - 0.07 13.1 1.1 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) zf-RING_2 PF13639.1 EME80011.1 - 1.8e-13 50.0 9.4 1.8e-13 50.0 6.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EME80011.1 - 4.3e-09 35.8 8.9 1.5e-08 34.1 6.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME80011.1 - 1.1e-08 35.0 7.7 1.1e-08 35.0 5.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME80011.1 - 3.2e-08 33.0 5.5 9.6e-08 31.5 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME80011.1 - 6.2e-08 32.5 7.9 6.2e-08 32.5 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME80011.1 - 1e-05 25.2 4.6 4.3e-05 23.2 3.2 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME80011.1 - 2.2e-05 24.1 6.9 2.2e-05 24.1 4.8 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME80011.1 - 7.5e-05 22.5 7.0 0.00022 21.0 4.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME80011.1 - 0.0047 16.6 5.2 0.016 14.9 3.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 EME80011.1 - 0.036 13.5 1.5 2 7.9 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif YdjO PF14169.1 EME80011.1 - 0.038 13.4 2.1 2.3 7.7 0.4 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_4 PF14570.1 EME80011.1 - 0.056 13.0 7.3 0.032 13.8 2.9 2.3 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EME80011.1 - 0.095 12.2 3.3 0.26 10.8 2.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 EME80011.1 - 0.49 9.9 6.1 2.4 7.7 4.2 2.2 1 1 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.3 EME80011.1 - 0.64 9.5 7.2 1.9 8.0 5.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TauD PF02668.11 EME80012.1 - 2e-06 27.7 0.0 2.3e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 EME80013.1 - 1.1e-36 126.7 0.1 1.6e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.2 EME80014.1 - 2.7e-33 115.7 0.0 3.2e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME80014.1 - 6.8e-17 61.5 0.0 1.2e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME80014.1 - 1.7e-11 44.1 0.0 5.9e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME80014.1 - 1.8e-05 24.4 0.0 7.2e-05 22.5 0.0 2.0 2 1 1 3 3 2 1 Putative lysophospholipase Thioesterase PF00975.15 EME80014.1 - 2.1e-05 24.8 0.0 3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 EME80014.1 - 2.4e-05 24.0 0.0 0.003 17.1 0.0 2.2 1 1 0 2 2 2 1 Serine hydrolase DUF1749 PF08538.5 EME80014.1 - 0.00021 20.3 0.0 0.00062 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 EME80014.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EME80014.1 - 0.0039 16.6 0.0 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 EME80014.1 - 0.0043 16.5 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EME80014.1 - 0.0049 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EME80014.1 - 0.008 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 EME80014.1 - 0.027 12.9 0.0 0.028 12.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.5 EME80014.1 - 0.054 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.20 EME80014.1 - 0.095 12.3 0.1 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Fungal_trans PF04082.13 EME80015.1 - 0.033 13.0 0.3 0.063 12.1 0.2 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain TRAP_beta PF05753.9 EME80016.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CCDC-167 PF15188.1 EME80016.1 - 0.043 13.7 0.5 0.18 11.7 0.3 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Pyr_redox_3 PF13738.1 EME80017.1 - 1.4e-26 93.7 0.0 2.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME80017.1 - 5.5e-20 71.0 0.2 1.6e-18 66.2 0.1 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME80017.1 - 9.8e-09 35.1 0.0 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME80017.1 - 7.9e-08 31.6 0.0 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 EME80017.1 - 4e-07 29.2 0.2 2.8e-05 23.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME80017.1 - 2.8e-05 24.1 0.0 0.0005 20.0 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME80017.1 - 6e-05 23.3 0.2 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME80017.1 - 0.00021 20.3 0.1 0.036 12.9 0.0 3.7 5 0 0 5 5 5 1 Lycopene cyclase protein DAO PF01266.19 EME80017.1 - 0.0003 19.8 0.3 0.021 13.7 0.0 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME80017.1 - 0.014 15.1 3.3 13 5.5 0.0 4.4 5 0 0 5 5 5 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EME80017.1 - 0.016 14.1 0.1 0.38 9.5 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.10 EME80017.1 - 0.019 13.1 0.0 0.55 8.3 0.0 2.4 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Flavodoxin_5 PF12724.2 EME80017.1 - 0.11 12.5 0.1 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 Flavodoxin domain Glyco_hydro_76 PF03663.9 EME80018.1 - 1.7e-42 146.1 8.4 1.7e-42 146.1 5.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EME80018.1 - 0.00017 20.7 0.6 0.033 13.2 0.0 2.6 2 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EME80018.1 - 0.016 14.4 0.1 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus HlyD PF00529.15 EME80019.1 - 0.34 10.1 5.6 0.55 9.4 3.9 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Pro_isomerase PF00160.16 EME80021.1 - 7.3e-47 159.4 0.6 9.3e-47 159.1 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 EME80022.1 - 4.9e-25 88.0 0.2 5.5e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EME80022.1 - 0.0012 17.4 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Asp PF00026.18 EME80024.1 - 1e-36 126.8 0.1 1.1e-36 126.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME80024.1 - 1.8e-12 47.5 0.1 3e-11 43.5 0.0 2.0 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME80024.1 - 0.048 14.1 0.1 0.76 10.3 0.0 2.3 1 1 0 1 1 1 0 Aspartyl protease zf-RING_2 PF13639.1 EME80025.1 - 1.3e-11 44.0 13.0 3e-11 42.9 9.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME80025.1 - 7.9e-10 38.5 12.4 1.6e-09 37.6 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME80025.1 - 1.3e-08 34.3 12.1 2.5e-08 33.4 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME80025.1 - 5.6e-08 32.3 8.8 1.1e-07 31.3 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME80025.1 - 1.1e-07 31.4 12.2 2.4e-07 30.3 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME80025.1 - 1.5e-07 31.1 11.8 3.3e-07 30.0 8.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EME80025.1 - 2.4e-05 24.3 11.0 6e-05 23.0 7.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EME80025.1 - 9.4e-05 22.0 10.6 0.00023 20.8 7.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DNA_ligase_ZBD PF03119.11 EME80025.1 - 0.011 15.4 10.3 0.58 9.9 0.2 3.4 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Apc11 PF12861.2 EME80025.1 - 0.022 14.5 6.6 0.041 13.7 4.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EME80025.1 - 0.023 14.4 10.4 0.26 11.1 1.0 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 EME80025.1 - 0.026 14.0 11.0 0.25 10.9 7.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EME80025.1 - 0.21 11.4 7.4 0.36 10.7 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-C4_Topoisom PF01396.14 EME80025.1 - 0.31 10.5 4.7 2.5 7.6 0.1 2.7 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-Nse PF11789.3 EME80025.1 - 0.39 10.2 7.8 0.76 9.3 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 EME80025.1 - 0.55 9.7 8.9 0.57 9.7 2.4 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-C2HC5 PF06221.8 EME80025.1 - 0.59 9.9 7.2 0.71 9.6 1.2 2.5 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-RING_6 PF14835.1 EME80025.1 - 1.2 8.9 7.5 8.1 6.3 5.2 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EME80025.1 - 1.3 8.5 12.1 2.4 7.7 8.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Rtf2 PF04641.7 EME80025.1 - 2.1 7.4 3.6 4.1 6.5 2.5 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger IBR PF01485.16 EME80025.1 - 2.1 8.2 12.5 8.8 6.2 8.6 2.1 1 1 1 2 2 2 0 IBR domain DNA_pol_E_B PF04042.11 EME80026.1 - 6.7e-47 159.4 0.0 1e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B AMP-binding PF00501.23 EME80028.1 - 9.3e-97 324.0 0.0 1.2e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME80028.1 - 1.7e-11 44.8 0.1 6.6e-11 43.0 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.4 EME80030.1 - 3.1e-44 150.4 0.0 3.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EME80030.1 - 3e-07 30.1 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME80030.1 - 8.5e-06 25.2 0.0 1.5e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME80030.1 - 0.00012 22.4 0.0 0.00027 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME80030.1 - 0.00033 20.6 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80030.1 - 0.0011 19.5 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME80030.1 - 0.042 12.8 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DDE_Tnp_4 PF13359.1 EME80032.1 - 1.5e-09 37.6 0.1 1.7e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 EME80032.1 - 6.3e-05 22.4 0.0 7.1e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 EME80032.1 - 0.00028 21.0 0.1 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.16 EME80032.1 - 0.0094 15.5 0.1 0.0097 15.4 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain BNR_2 PF13088.1 EME80033.1 - 0.0008 18.7 0.2 0.0018 17.6 0.0 1.7 1 1 1 2 2 2 1 BNR repeat-like domain RRM_5 PF13893.1 EME80034.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRA-PH PF01503.12 EME80034.1 - 0.036 14.3 1.2 0.045 14.0 0.1 1.7 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase IF-2B PF01008.12 EME80035.1 - 9.2e-75 251.2 0.9 1.1e-74 250.9 0.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family MFS_1 PF07690.11 EME80036.1 - 1.2e-34 119.6 33.5 1.7e-34 119.0 23.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF962 PF06127.6 EME80036.1 - 0.0068 16.2 0.2 0.057 13.3 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF962) Peptidase_M48 PF01435.13 EME80038.1 - 1.3e-48 165.5 0.0 1.8e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EME80038.1 - 0.0077 15.2 0.1 0.023 13.6 0.1 1.7 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.4 EME80038.1 - 0.035 13.4 0.1 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) FtsX PF02687.16 EME80038.1 - 8.5 6.1 9.8 97 2.7 0.0 3.0 2 1 0 2 2 2 0 FtsX-like permease family Glyco_hydro_32N PF00251.15 EME80039.1 - 4.1e-76 256.2 2.9 5.5e-76 255.8 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EME80039.1 - 0.0033 17.7 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal RNA_polI_A14 PF08203.6 EME80041.1 - 0.0046 17.1 0.0 0.024 14.8 0.0 2.2 1 1 1 2 2 2 1 Yeast RNA polymerase I subunit RPA14 PHBC_N PF12551.3 EME80043.1 - 0.013 14.9 0.6 2.5 7.7 0.0 3.1 2 1 1 3 3 3 0 Poly-beta-hydroxybutyrate polymerase N terminal ADK PF00406.17 EME80044.1 - 1.2e-47 161.5 0.0 1.5e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EME80044.1 - 5.5e-09 36.4 0.0 8.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME80044.1 - 1.5e-07 32.2 0.0 2.6e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME80044.1 - 7.5e-07 29.1 0.0 1.9e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EME80044.1 - 9.6e-06 25.0 0.5 0.047 13.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase PAS_7 PF12860.2 EME80044.1 - 0.053 13.5 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 PAS fold zf-RING_2 PF13639.1 EME80046.1 - 1e-06 28.4 7.8 2.3e-06 27.3 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME80046.1 - 2.1e-05 24.4 9.2 4.2e-05 23.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME80046.1 - 0.0022 17.6 5.3 0.0041 16.7 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME80046.1 - 0.0047 16.4 6.3 0.01 15.3 4.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EME80046.1 - 0.1 12.3 6.1 0.22 11.2 4.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_tran_WecB PF03808.8 EME80046.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family zf-C3HC4 PF00097.20 EME80046.1 - 0.24 11.0 8.4 0.51 10.0 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME80046.1 - 0.8 9.8 5.0 2.2 8.4 3.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DAHP_synth_1 PF00793.15 EME80047.1 - 2.3e-96 321.6 0.0 3e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family zf-RING_2 PF13639.1 EME80048.1 - 1.4e-08 34.4 6.7 1.4e-08 34.4 4.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME80048.1 - 3e-05 23.9 6.1 3e-05 23.9 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME80048.1 - 0.00025 20.7 4.7 0.00025 20.7 3.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME80048.1 - 0.0012 18.4 2.3 0.0012 18.4 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME80048.1 - 0.024 14.3 5.2 0.024 14.3 3.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EME80048.1 - 0.084 12.3 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-rbx1 PF12678.2 EME80048.1 - 0.16 12.1 10.4 0.17 12.0 5.3 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EME80048.1 - 0.22 11.4 3.9 0.13 12.1 1.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EME80048.1 - 0.79 9.5 3.0 0.61 9.9 0.6 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DIOX_N PF14226.1 EME80049.1 - 3.4e-14 53.3 0.0 6.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME80049.1 - 8.1e-12 45.3 0.1 1.6e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4387 PF14330.1 EME80051.1 - 8e-33 112.7 0.0 1.5e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EME80051.1 - 3.4e-18 65.2 0.0 2e-16 59.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Pam17 PF08566.5 EME80054.1 - 5.9e-55 185.6 0.0 8e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ADH_zinc_N PF00107.21 EME80055.1 - 9.8e-25 86.5 2.0 1.4e-24 86.1 0.6 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME80055.1 - 3e-16 59.1 2.8 6.9e-16 57.9 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_32 PF13679.1 EME80055.1 - 0.0072 16.0 0.6 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80055.1 - 0.014 16.0 0.1 0.035 14.6 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EME80055.1 - 0.049 14.5 0.5 0.13 13.1 0.4 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase MT0933_antitox PF14013.1 EME80057.1 - 0.76 9.9 6.7 8.8 6.5 1.6 2.8 2 1 0 2 2 2 0 MT0933-like antitoxin protein cobW PF02492.14 EME80058.1 - 9.7e-33 113.0 0.4 5.2e-32 110.7 0.1 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EME80058.1 - 2.9e-05 23.7 0.1 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EME80058.1 - 0.00051 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.17 EME80058.1 - 0.0016 17.8 0.1 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.13 EME80058.1 - 0.0017 17.9 0.1 0.0044 16.5 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EME80058.1 - 0.0019 17.8 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EME80058.1 - 0.0037 17.1 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME80058.1 - 0.0069 16.5 0.1 0.02 15.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME80058.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EME80058.1 - 0.0091 16.3 0.0 0.025 14.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter CbiA PF01656.18 EME80058.1 - 0.01 15.2 0.2 0.15 11.4 0.2 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 EME80058.1 - 0.039 13.6 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.1 EME80058.1 - 0.044 13.3 0.0 0.067 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EME80058.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EME80058.1 - 0.066 13.1 0.2 0.22 11.4 0.0 1.9 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EME80058.1 - 0.069 12.6 0.1 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EME80058.1 - 0.073 12.7 0.0 1 8.9 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EME80058.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EME80058.1 - 0.11 12.8 0.1 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EME80058.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 EME80058.1 - 0.12 11.2 0.6 0.23 10.3 0.4 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EME80058.1 - 0.37 11.0 1.6 0.75 10.0 0.5 1.9 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.21 EME80060.1 - 1.6e-37 128.6 0.0 1.8e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EME80061.1 - 1.5e-72 237.0 21.0 7.3e-09 35.1 0.0 11.1 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.6 EME80061.1 - 4.4e-35 120.3 1.8 8.1e-35 119.5 1.2 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EME80061.1 - 1.4e-12 46.5 18.4 0.11 10.6 0.7 8.4 4 2 3 7 7 7 7 Nucleoporin Nup120/160 RPEL PF02755.10 EME80062.1 - 0.56 9.6 2.8 1 8.7 0.1 2.5 3 0 0 3 3 3 0 RPEL repeat adh_short PF00106.20 EME80063.1 - 6e-17 62.0 0.5 1.9e-15 57.1 0.5 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME80063.1 - 1.1e-07 31.7 0.3 1.5e-07 31.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EME80063.1 - 0.043 12.7 0.2 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase MFS_1 PF07690.11 EME80065.1 - 2e-05 23.4 5.1 3.2e-05 22.8 3.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 EME80065.1 - 0.0063 15.7 1.8 0.01 15.0 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sugar_tr PF00083.19 EME80067.1 - 2.4e-39 135.1 16.4 5e-39 134.1 11.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME80067.1 - 6.6e-09 34.9 20.9 3.1e-08 32.7 9.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 EME80069.1 - 0.029 14.4 0.9 0.045 13.8 0.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Frag1 PF10277.4 EME80070.1 - 2.5e-32 112.1 20.7 2.8e-32 111.9 14.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MARVEL PF01284.18 EME80070.1 - 4.8 6.9 17.3 27 4.5 10.8 2.7 1 1 2 3 3 3 0 Membrane-associating domain DUF4064 PF13273.1 EME80070.1 - 8.5 6.5 7.9 1.2 9.2 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) OPT PF03169.10 EME80071.1 - 1.5e-162 542.3 52.8 1.2e-161 539.3 36.6 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like_2 PF13013.1 EME80072.1 - 0.0073 16.0 0.2 0.017 14.8 0.1 1.9 1 1 0 1 1 1 1 F-box-like domain DUF3135 PF11333.3 EME80072.1 - 0.09 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) G-patch PF01585.18 EME80073.1 - 0.00033 20.3 0.0 0.0023 17.6 0.0 2.4 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 EME80073.1 - 0.13 10.6 52.4 0.18 10.2 36.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_23 PF13476.1 EME80073.1 - 0.66 10.2 16.5 0.96 9.7 11.4 1.2 1 0 0 1 1 1 0 AAA domain PI3_PI4_kinase PF00454.22 EME80074.1 - 1.8e-39 135.6 0.0 6.7e-39 133.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EME80074.1 - 2.6e-24 85.4 0.2 9.6e-24 83.5 0.1 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4072 PF13284.1 EME80074.1 - 0.011 15.9 4.3 2.1 8.6 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) DUF4135 PF13575.1 EME80074.1 - 0.073 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Arm PF00514.18 EME80074.1 - 0.56 10.1 4.2 7.4 6.5 0.3 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Epimerase PF01370.16 EME80076.1 - 1.8e-07 30.8 0.1 0.0018 17.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EME80076.1 - 3.8e-06 27.2 0.1 8.8e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EME80076.1 - 0.0015 17.2 0.0 0.039 12.6 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family YwqJ-deaminase PF14431.1 EME80077.1 - 0.027 14.3 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 YwqJ-like deaminase Proteasome PF00227.21 EME80079.1 - 3.8e-37 127.4 0.0 4.3e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit IN_DBD_C PF00552.16 EME80080.1 - 0.014 14.8 0.2 0.034 13.6 0.1 1.7 1 0 0 1 1 1 0 Integrase DNA binding domain ATP_bind_4 PF01902.12 EME80080.1 - 0.095 12.0 0.1 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 ATP-binding region ActA PF05058.7 EME80081.1 - 0.041 11.8 2.0 0.053 11.5 1.4 1.1 1 0 0 1 1 1 0 ActA Protein CHORD PF04968.7 EME80081.1 - 1.1 9.5 11.9 0.13 12.5 1.8 2.5 1 1 1 2 2 2 0 CHORD Glyco_hydro_3 PF00933.16 EME80082.1 - 3.7e-87 292.0 0.0 5.4e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME80082.1 - 2.5e-49 167.8 0.1 1.1e-48 165.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME80082.1 - 3.3e-16 58.9 0.1 5.8e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain GTP_EFTU PF00009.22 EME80083.1 - 3.6e-39 134.1 0.0 5.9e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EME80083.1 - 3.1e-36 123.2 0.8 6.6e-36 122.2 0.6 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EME80083.1 - 3.2e-12 46.3 0.3 7e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME80083.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase CFEM PF05730.6 EME80084.1 - 1.1e-12 47.5 10.9 1.1e-12 47.5 7.6 2.0 3 0 0 3 3 3 1 CFEM domain Rifin_STEVOR PF02009.11 EME80084.1 - 2 8.0 4.8 2.3 7.7 3.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family MAP65_ASE1 PF03999.7 EME80084.1 - 2.5 6.5 4.6 2.9 6.3 3.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SCF PF02404.10 EME80084.1 - 3.7 6.6 6.1 5.4 6.1 4.2 1.2 1 0 0 1 1 1 0 Stem cell factor Period_C PF12114.3 EME80084.1 - 3.8 7.0 13.5 5.4 6.5 9.4 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Med3 PF11593.3 EME80084.1 - 8.5 5.5 19.3 9.9 5.2 13.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn_clus PF00172.13 EME80086.1 - 0.013 15.3 6.2 0.041 13.7 4.3 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.22 EME80086.1 - 0.047 14.1 0.0 0.65 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phage_CII PF05269.6 EME80086.1 - 0.12 12.4 0.0 1.6 8.7 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage CII protein DUF1400 PF07176.6 EME80086.1 - 0.19 11.6 0.1 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) C2 PF00168.25 EME80087.1 - 3.1e-19 68.5 0.0 2.6e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain AA_permease PF00324.16 EME80088.1 - 1e-143 479.2 35.1 1.1e-143 479.0 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME80088.1 - 1.7e-37 128.9 36.9 2.4e-37 128.5 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.1 EME80088.1 - 2.8 7.9 9.0 11 6.0 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) UQ_con PF00179.21 EME80089.1 - 6.5e-26 90.4 0.0 1.2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.1 EME80089.1 - 4e-15 56.3 1.4 3.2e-13 50.1 0.1 2.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EME80089.1 - 6.8e-13 48.7 0.3 4.4e-11 42.8 0.0 3.0 3 0 0 3 3 3 1 von Willebrand factor type A domain U-box PF04564.10 EME80089.1 - 5.4e-10 39.0 0.0 2.1e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain SIS PF01380.17 EME80090.1 - 8.1e-54 180.7 0.0 1.3e-29 102.4 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EME80090.1 - 2.3e-26 92.3 0.0 7.9e-18 64.2 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EME80090.1 - 2.9e-19 69.3 0.0 6.7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EME80090.1 - 1.6e-12 47.2 0.0 3.4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EME80090.1 - 3.4e-06 25.9 0.0 5.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Ribosomal_L36 PF00444.13 EME80090.1 - 0.022 14.7 0.1 0.065 13.2 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein L36 SIS_2 PF13580.1 EME80090.1 - 0.038 13.6 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 SIS domain Ferric_reduct PF01794.14 EME80091.1 - 2.4e-21 76.0 7.6 4.5e-21 75.2 5.3 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME80091.1 - 5.2e-10 39.1 0.1 4.9e-09 36.0 0.1 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME80091.1 - 2.5e-09 37.2 0.1 8.5e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain tRNA-synt_1g PF09334.6 EME80092.1 - 9.9e-114 380.0 0.0 1.9e-113 379.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EME80092.1 - 8e-25 86.8 0.5 1.6e-10 39.6 0.0 3.4 1 1 3 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EME80092.1 - 1.4e-06 27.6 0.0 0.0024 17.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain AlaDh_PNT_N PF05222.10 EME80093.1 - 1.1e-28 99.9 0.0 1.7e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EME80093.1 - 3.7e-11 42.8 0.0 5.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2675 PF11247.3 EME80093.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) BTB PF00651.26 EME80094.1 - 1.2e-10 41.3 0.0 3.6e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Frag1 PF10277.4 EME80095.1 - 1.5e-40 139.0 15.1 1.7e-40 138.8 10.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SUR7 PF06687.7 EME80095.1 - 1.6 8.2 5.3 9.8 5.6 0.1 2.3 1 1 1 2 2 2 0 SUR7/PalI family Tetraspannin PF00335.15 EME80095.1 - 7.5 5.7 9.4 0.13 11.4 0.8 1.9 2 0 0 2 2 2 0 Tetraspanin family CTP_transf_1 PF01148.15 EME80096.1 - 5e-05 23.0 10.9 5e-05 23.0 7.5 3.7 3 2 0 3 3 3 1 Cytidylyltransferase family zf-DHHC PF01529.15 EME80096.1 - 0.13 11.6 6.9 0.015 14.7 1.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3735 PF12537.3 EME80096.1 - 0.15 12.1 1.3 0.35 10.9 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Ribonuclease_3 PF00636.21 EME80097.1 - 0.0076 16.6 0.0 0.022 15.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain AMP-binding PF00501.23 EME80098.1 - 4.5e-69 232.8 0.0 6.1e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME80098.1 - 4.2e-11 43.6 0.0 8.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HipA_C PF07804.7 EME80099.1 - 0.13 12.4 0.2 0.66 10.1 0.1 2.1 1 1 0 1 1 1 0 HipA-like C-terminal domain zf-RING_2 PF13639.1 EME80100.1 - 6.1e-10 38.7 10.9 6.1e-10 38.7 7.6 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME80100.1 - 1.4e-06 27.8 8.2 1.4e-06 27.8 5.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME80100.1 - 1.8e-06 27.9 4.2 3.6e-06 26.9 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME80100.1 - 0.0002 21.3 10.5 0.0002 21.3 7.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME80100.1 - 0.00034 20.2 9.4 0.00034 20.2 6.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME80100.1 - 0.0043 16.8 3.2 0.0097 15.7 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EME80100.1 - 0.012 15.2 9.3 0.012 15.2 6.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EME80100.1 - 1.1 9.0 6.6 2.8 7.7 4.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Abhydrolase_5 PF12695.2 EME80101.1 - 4.6e-22 78.3 0.0 5.9e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME80101.1 - 9.6e-18 64.8 0.0 3e-16 60.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EME80101.1 - 1.1e-07 30.6 0.1 0.035 12.6 0.1 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EME80101.1 - 3e-05 23.5 0.0 0.042 13.3 0.0 2.4 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EME80101.1 - 3.2e-05 23.6 0.0 0.013 15.0 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EME80101.1 - 0.00021 20.9 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EME80101.1 - 0.00034 19.4 0.0 0.00048 18.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 EME80101.1 - 0.00041 19.8 0.0 0.00068 19.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EME80101.1 - 0.001 18.8 0.0 0.066 12.9 0.0 2.3 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 EME80101.1 - 0.0016 17.9 0.0 0.092 12.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 EME80101.1 - 0.0023 17.2 0.0 0.42 9.8 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EME80101.1 - 0.0033 16.6 0.0 0.021 14.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 EME80101.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Proteasome PF00227.21 EME80102.1 - 2.2e-48 164.0 0.5 2.6e-48 163.8 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit CRA PF06589.6 EME80106.1 - 0.054 12.8 0.0 0.054 12.8 0.0 1.0 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Cyclin PF08613.6 EME80107.1 - 4e-33 114.9 1.3 1.2e-13 51.7 0.0 3.5 3 0 0 3 3 3 3 Cyclin Glyco_transf_20 PF00982.16 EME80110.1 - 8.3e-162 538.9 0.1 1.1e-161 538.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME80110.1 - 4.1e-38 130.6 0.0 7.4e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DUF2834 PF11196.3 EME80112.1 - 0.0055 16.8 3.5 0.36 10.9 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) zf-RING_2 PF13639.1 EME80113.1 - 2.1e-15 56.2 5.4 3.5e-15 55.5 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME80113.1 - 1.8e-08 34.3 6.2 4.5e-08 33.0 4.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME80113.1 - 3.1e-08 33.1 4.8 5.1e-08 32.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME80113.1 - 1.3e-07 31.1 2.8 2.1e-07 30.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME80113.1 - 1.4e-07 31.4 3.9 2.3e-07 30.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME80113.1 - 8.5e-07 28.6 4.3 1.4e-06 27.9 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME80113.1 - 8.8e-06 25.4 1.1 1.4e-05 24.7 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EME80113.1 - 0.0021 18.0 5.2 0.0039 17.2 3.6 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EME80113.1 - 0.0061 16.5 8.1 0.015 15.2 5.6 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EME80113.1 - 0.0098 15.4 6.4 0.023 14.2 4.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EME80113.1 - 0.029 13.8 1.4 0.048 13.1 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EME80113.1 - 0.066 12.9 0.6 0.13 11.9 0.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 EME80113.1 - 0.088 12.6 1.5 0.16 11.7 1.1 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 EME80113.1 - 0.2 11.3 9.0 0.15 11.7 4.7 2.0 1 1 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EME80113.1 - 0.38 10.6 4.4 1.2 9.0 3.1 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EME80113.1 - 5.1 6.9 16.4 0.38 10.5 1.9 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EME80113.1 - 5.5 7.0 7.5 4.2 7.4 4.0 1.8 1 1 0 1 1 1 0 RING-like domain Nop14 PF04147.7 EME80113.1 - 8.9 4.0 15.3 9.3 4.0 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family Homeobox_KN PF05920.6 EME80114.1 - 0.22 11.2 10.4 1.3 8.7 0.3 3.0 1 1 1 2 2 2 0 Homeobox KN domain Lipase_3 PF01764.20 EME80115.1 - 2.9e-31 107.9 0.0 4.2e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EME80115.1 - 0.002 17.9 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME80115.1 - 0.0054 16.6 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME80115.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EME80115.1 - 0.011 15.1 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EME80115.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EME80115.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 EME80115.1 - 0.048 13.2 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EME80115.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.9 EME80115.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3463 PF11946.3 EME80115.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3463) PGAMP PF07644.6 EME80116.1 - 0.061 13.0 0.2 0.061 13.0 0.1 1.7 2 0 0 2 2 2 0 Planctomycete PGAMP Aminotran_3 PF00202.16 EME80118.1 - 8.1e-109 363.5 0.0 1e-108 363.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EME80118.1 - 0.00013 21.2 0.0 0.00028 20.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EME80118.1 - 0.0005 19.1 0.0 0.00084 18.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II TPPII_N PF12583.3 EME80120.1 - 1.1 9.4 4.6 2.3 8.3 3.2 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Pex14_N PF04695.8 EME80120.1 - 2.2 8.3 5.5 7.3 6.6 0.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LSM PF01423.17 EME80121.1 - 4.9e-16 58.0 0.0 6.2e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EME80122.1 - 1.6e-22 79.0 0.0 2.2e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EME80122.1 - 2.9e-21 75.0 0.1 7.8e-21 73.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 FAA_hydrolase PF01557.13 EME80123.1 - 6.3e-58 195.7 0.0 1e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family AAA PF00004.24 EME80124.1 - 8.2e-17 61.6 0.0 1.8e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME80124.1 - 0.0027 17.8 0.0 0.018 15.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EME80124.1 - 0.0066 16.4 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EME80124.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EME80124.1 - 0.069 12.7 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain C2 PF00168.25 EME80125.1 - 8.4e-15 54.3 0.0 1.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA PF00004.24 EME80129.1 - 7.8e-55 184.6 0.0 1.3e-42 145.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EME80129.1 - 5.1e-27 93.7 0.3 1.2e-26 92.5 0.2 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EME80129.1 - 4e-12 46.4 1.9 6.2e-06 26.3 0.0 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 EME80129.1 - 9.4e-09 35.4 0.0 0.0067 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EME80129.1 - 3.2e-08 33.3 0.3 4.1e-05 23.3 0.0 3.5 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EME80129.1 - 1.9e-07 31.2 1.0 0.009 16.1 0.0 4.4 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EME80129.1 - 3.8e-07 30.0 0.0 0.0041 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EME80129.1 - 1.4e-06 27.9 0.0 0.0051 16.5 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 EME80129.1 - 1.8e-06 27.1 0.0 0.012 14.6 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EME80129.1 - 5.4e-06 26.7 0.0 0.003 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME80129.1 - 7.7e-06 26.7 0.0 0.11 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EME80129.1 - 2.2e-05 23.9 0.4 0.045 13.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 EME80129.1 - 2.5e-05 24.0 0.1 0.16 11.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME80129.1 - 2.8e-05 24.0 0.1 0.37 10.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EME80129.1 - 4.5e-05 22.6 0.0 0.083 11.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Sigma54_activ_2 PF14532.1 EME80129.1 - 0.0003 20.8 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.21 EME80129.1 - 0.00035 20.0 0.0 0.023 14.1 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EME80129.1 - 0.00073 19.5 0.0 0.4 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME80129.1 - 0.0029 17.7 0.0 4.1 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.8 EME80129.1 - 0.0035 16.1 0.0 0.92 8.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus UPF0079 PF02367.12 EME80129.1 - 0.0035 16.9 0.1 0.083 12.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EME80129.1 - 0.005 16.2 5.2 2 7.7 0.1 4.0 2 2 1 4 4 4 1 AAA domain Mg_chelatase PF01078.16 EME80129.1 - 0.0054 15.9 0.2 0.69 9.0 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EME80129.1 - 0.01 15.1 0.2 1.6 7.9 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Cytidylate_kin2 PF13189.1 EME80129.1 - 0.011 15.6 0.0 3.2 7.6 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family ABC_tran PF00005.22 EME80129.1 - 0.011 15.9 0.0 5.1 7.4 0.0 2.9 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 EME80129.1 - 0.014 14.5 0.1 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 KaiC SKI PF01202.17 EME80129.1 - 0.016 15.1 0.0 4.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Viral_helicase1 PF01443.13 EME80129.1 - 0.034 13.6 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EME80129.1 - 0.042 13.5 0.0 10 5.6 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase Vps4_C PF09336.5 EME80129.1 - 0.075 12.9 0.0 0.61 10.0 0.0 2.6 3 0 0 3 3 1 0 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 EME80129.1 - 0.08 11.8 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 EME80129.1 - 0.094 11.3 0.2 0.79 8.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EME80129.1 - 0.12 11.7 0.5 2 7.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.15 EME80129.1 - 0.15 11.7 0.3 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 EME80129.1 - 0.15 11.7 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 EME80129.1 - 0.18 10.7 0.0 7.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 EME80129.1 - 0.19 10.6 2.3 0.99 8.3 0.1 2.5 2 1 1 3 3 2 0 KAP family P-loop domain NB-ARC PF00931.17 EME80129.1 - 0.41 9.4 0.5 6.5 5.5 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain Thioredoxin_7 PF13899.1 EME80130.1 - 1.3e-13 50.8 0.0 2.7e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EME80130.1 - 1.1e-12 47.2 0.4 4.6e-12 45.2 0.3 2.1 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EME80130.1 - 1.4e-07 31.5 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.1 EME80130.1 - 0.0025 17.9 0.2 0.0073 16.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.10 EME80130.1 - 0.0048 16.6 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 UBA PF00627.26 EME80130.1 - 0.053 13.3 0.0 0.21 11.4 0.0 2.1 1 0 0 1 1 1 0 UBA/TS-N domain KCNQC3-Ank-G_bd PF11956.3 EME80131.1 - 0.043 13.8 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 Proteasome PF00227.21 EME80132.1 - 2.6e-48 163.8 0.3 2.9e-33 114.7 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EME80132.1 - 8.6e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Syja_N PF02383.13 EME80133.1 - 8.4e-87 290.9 0.0 1.2e-86 290.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EME80133.1 - 8.3e-23 81.6 0.4 1.5e-22 80.7 0.3 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PT PF04886.7 EME80134.1 - 0.042 13.1 75.9 0.068 12.4 9.7 4.6 2 1 1 3 3 3 0 PT repeat Sec10 PF07393.6 EME80135.1 - 5.8e-150 500.7 0.0 8.3e-150 500.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EME80135.1 - 8.5e-06 25.2 0.0 2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME80135.1 - 6e-05 22.6 1.6 0.00012 21.7 0.1 2.2 3 0 0 3 3 3 1 F-box-like Abhydrolase_6 PF12697.2 EME80137.1 - 2.6e-22 79.8 0.0 6.1e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME80137.1 - 3.8e-08 33.1 0.0 3.6e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME80137.1 - 1.8e-05 24.5 0.0 9e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.24 EME80139.1 - 1.1e-40 138.8 0.0 4.1e-40 137.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME80139.1 - 4.2e-25 87.4 0.2 1e-24 86.1 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 EME80139.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) EF_TS PF00889.14 EME80139.1 - 0.75 9.0 4.9 8.1 5.6 2.4 2.4 2 0 0 2 2 2 0 Elongation factor TS Prenyltrans PF00432.16 EME80140.1 - 3.5e-59 196.0 9.7 1.1e-14 53.6 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EME80140.1 - 1.3e-37 128.6 0.0 2.5e-13 50.4 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME80140.1 - 4.7e-12 45.8 0.0 5.2e-07 29.6 0.0 3.6 2 1 1 3 3 3 2 Prenyltransferase-like RhoGAP PF00620.22 EME80141.1 - 4.8e-28 97.6 0.0 8.1e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-C2H2_2 PF12756.2 EME80143.1 - 0.034 14.2 0.2 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Spo12 PF05032.7 EME80144.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Spo12 family MgsA_C PF12002.3 EME80147.1 - 4.8e-58 195.5 0.0 8.1e-58 194.8 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EME80147.1 - 1.3e-14 54.5 0.0 3.3e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME80147.1 - 1.3e-11 43.9 0.0 2.6e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME80147.1 - 1.3e-05 24.8 0.1 6e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 EME80147.1 - 1.5e-05 24.5 0.0 0.00027 20.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EME80147.1 - 6.8e-05 22.6 0.0 0.0035 17.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EME80147.1 - 0.00013 21.2 0.1 0.24 10.5 0.0 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EME80147.1 - 0.00015 21.8 0.1 0.00054 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EME80147.1 - 0.00018 21.0 0.0 0.00055 19.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME80147.1 - 0.00074 20.3 0.0 0.0018 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EME80147.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EME80147.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME80147.1 - 0.0025 17.8 0.2 0.11 12.4 0.0 3.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EME80147.1 - 0.0037 17.2 0.7 0.0074 16.2 0.2 1.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EME80147.1 - 0.0038 16.0 0.0 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EME80147.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 EME80147.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EME80147.1 - 0.02 15.2 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EME80147.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase ResIII PF04851.10 EME80147.1 - 0.041 13.7 0.2 4.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EME80147.1 - 0.047 13.2 0.1 0.14 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain FKBP_C PF00254.23 EME80149.1 - 6.8e-24 83.7 0.0 8e-24 83.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Big_5 PF13205.1 EME80149.1 - 0.12 12.9 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain PHP PF02811.14 EME80150.1 - 2.9e-13 49.9 0.2 6.7e-13 48.8 0.1 1.6 1 1 0 1 1 1 1 PHP domain Pkinase PF00069.20 EME80151.1 - 2.1e-75 253.2 0.0 3e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80151.1 - 3.8e-37 127.7 0.0 5.2e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EME80151.1 - 7.1e-16 58.0 0.1 1.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EME80151.1 - 1.1e-09 37.7 0.0 5.8e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EME80151.1 - 0.0035 16.2 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EME80151.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Git3 PF11710.3 EME80153.1 - 9e-18 64.5 15.1 4.4e-17 62.3 10.5 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EME80153.1 - 0.00021 20.9 0.1 0.00073 19.2 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EME80153.1 - 0.0087 14.9 16.6 0.014 14.2 11.3 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Zw10 PF06248.8 EME80154.1 - 1.4e-08 33.3 4.6 0.00012 20.4 1.6 3.1 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EME80154.1 - 9.7e-06 24.9 0.1 3.1e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Hrs_helical PF12210.3 EME80154.1 - 0.043 14.0 0.5 6.5 7.0 0.2 2.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Nop14 PF04147.7 EME80154.1 - 5.6 4.7 9.5 9.9 3.9 6.6 1.3 1 0 0 1 1 1 0 Nop14-like family G_glu_transpept PF01019.16 EME80155.1 - 1.5e-154 515.2 0.1 1.7e-154 515.0 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HlyIII PF03006.15 EME80156.1 - 2.4e-57 193.9 21.3 3e-57 193.5 14.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related LemA PF04011.7 EME80156.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 LemA family DUF373 PF04123.8 EME80156.1 - 0.48 9.3 3.0 0.78 8.7 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1749 PF08538.5 EME80157.1 - 5.5e-66 222.5 0.0 6.1e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EME80157.1 - 2.7e-10 40.5 0.0 3.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME80157.1 - 3.2e-05 23.7 0.0 4.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EME80157.1 - 3.4e-05 23.2 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EME80157.1 - 0.00087 18.9 0.0 0.0033 17.0 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.15 EME80157.1 - 0.0034 16.9 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EME80157.1 - 0.0058 15.7 0.0 0.0077 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EME80157.1 - 0.02 13.7 0.0 0.037 12.8 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme LCAT PF02450.10 EME80157.1 - 0.05 12.5 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cutinase PF01083.17 EME80157.1 - 0.069 12.8 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_8 PF06259.7 EME80157.1 - 0.093 12.2 0.0 7.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_3 PF07859.8 EME80157.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tetraspannin PF00335.15 EME80158.1 - 0.00094 18.5 3.4 0.00094 18.5 2.4 1.6 1 1 1 2 2 2 1 Tetraspanin family DUF202 PF02656.10 EME80158.1 - 0.045 13.9 2.8 3 8.1 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) BCD PF15461.1 EME80158.1 - 0.071 12.5 2.8 0.054 12.8 0.5 1.7 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF3329 PF11808.3 EME80158.1 - 0.086 12.9 1.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) MARVEL PF01284.18 EME80158.1 - 0.22 11.3 10.1 0.4 10.4 6.0 1.9 1 1 1 2 2 2 0 Membrane-associating domain DUF1218 PF06749.7 EME80158.1 - 0.61 10.5 7.2 0.82 10.1 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Claudin_2 PF13903.1 EME80158.1 - 0.73 9.5 11.7 3.7 7.1 8.1 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction 7TMR-DISM_7TM PF07695.6 EME80158.1 - 0.92 9.1 7.9 0.059 13.0 1.8 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2700 PF10912.3 EME80158.1 - 2.8 7.9 5.9 1.4 8.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2700) PrgI PF12666.2 EME80158.1 - 5.1 7.3 6.3 1.8 8.7 2.0 2.0 2 0 0 2 2 2 0 PrgI family protein SWIB PF02201.13 EME80160.1 - 3.5e-28 97.0 0.7 9e-28 95.7 0.2 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EME80160.1 - 8.9e-14 51.0 3.2 1.4e-13 50.3 0.6 2.4 3 0 0 3 3 3 1 DEK C terminal domain FliT PF05400.8 EME80160.1 - 0.54 10.6 3.3 1.3 9.4 0.7 2.5 2 0 0 2 2 2 0 Flagellar protein FliT A_deaminase PF00962.17 EME80161.1 - 4.4e-31 108.0 0.0 6.9e-31 107.3 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase PI-PLC-X PF00388.14 EME80161.1 - 0.00017 20.9 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain eIF2A PF08662.6 EME80162.1 - 1.9e-40 138.6 5.8 2.9e-38 131.5 0.3 4.1 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EME80162.1 - 2.4e-06 27.4 0.0 5.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME80162.1 - 1e-05 25.0 0.0 2.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EME80162.1 - 0.00041 20.1 0.2 0.29 11.0 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_5 PF13893.1 EME80162.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M1 PF01433.15 EME80164.1 - 7.1e-140 466.5 0.3 1.3e-139 465.6 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EME80164.1 - 6.8e-95 318.0 1.2 6.8e-95 318.0 0.9 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EME80164.1 - 5.2e-21 75.0 0.1 1.3e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily 4HBT_3 PF13622.1 EME80165.1 - 9.2e-48 163.2 0.1 1.1e-47 163.0 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EME80165.1 - 0.02 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily NAD_synthase PF02540.12 EME80166.1 - 2.2e-24 85.6 0.0 1.2e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EME80166.1 - 2.3e-18 66.2 0.0 3.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ApoL PF05461.6 EME80166.1 - 0.0018 17.6 0.1 0.0029 16.9 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein L Asn_synthase PF00733.16 EME80166.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Tme5_EGF_like PF09064.5 EME80167.1 - 0.32 10.6 5.4 0.13 11.8 1.7 1.9 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like Toxin_6 PF05453.7 EME80167.1 - 2.9 8.1 6.2 0.44 10.8 0.9 2.2 2 0 0 2 2 2 0 BmTXKS1/BmP02 toxin family Macoilin PF09726.4 EME80167.1 - 7.8 4.6 6.0 8.4 4.5 4.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_47 PF01532.15 EME80168.1 - 1.3e-160 534.9 0.1 1.5e-160 534.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Aurora-A_bind PF09041.5 EME80168.1 - 0.016 14.9 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Aurora-A binding DUF1680 PF07944.7 EME80168.1 - 0.036 12.3 0.0 0.52 8.5 0.0 2.5 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) DUF2363 PF10155.4 EME80168.1 - 0.063 13.2 0.1 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) Oest_recep PF02159.10 EME80169.1 - 0.043 13.9 0.5 0.11 12.5 0.2 1.7 1 1 1 2 2 2 0 Oestrogen receptor RhoGEF PF00621.15 EME80170.1 - 2e-34 119.0 0.1 6.8e-34 117.2 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EME80170.1 - 5.8e-21 75.0 0.3 1.1e-20 74.1 0.2 1.5 1 0 0 1 1 1 1 BAR domain HhH-GPD PF00730.20 EME80171.1 - 7.4e-05 22.9 0.0 0.00011 22.4 0.0 1.4 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Pro_isomerase PF00160.16 EME80172.1 - 4.6e-48 163.3 0.1 9.6e-48 162.3 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EME80172.1 - 3.3e-15 55.2 0.2 6.1e-05 22.7 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ECIST_Cterm PF14784.1 EME80173.1 - 0.33 10.8 7.4 1.2 9.0 0.2 3.4 3 0 0 3 3 3 0 C-terminal domain of the ECSIT protein DUF3653 PF12375.3 EME80173.1 - 1.4 9.1 5.9 13 6.0 4.1 2.6 1 1 0 1 1 1 0 Phage protein MS_channel PF00924.13 EME80174.1 - 3.4e-11 42.8 0.2 3.4e-11 42.8 0.1 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 EME80174.1 - 0.0025 17.8 0.2 0.011 15.8 0.0 2.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EME80174.1 - 0.0054 15.9 0.4 0.03 13.6 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EME80174.1 - 0.02 14.7 0.1 0.42 10.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 EME80174.1 - 0.043 13.4 0.7 0.27 10.8 0.4 2.2 2 0 0 2 2 2 0 EF-hand domain pair AMP-binding_C_2 PF14535.1 EME80174.1 - 0.099 12.6 0.1 0.47 10.5 0.0 2.1 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EME80175.1 - 3e-15 56.5 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME80175.1 - 8.3e-05 22.3 0.0 0.00042 20.0 0.0 1.9 1 1 0 1 1 1 1 KR domain DUF1729 PF08354.5 EME80175.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) TRI12 PF06609.8 EME80176.1 - 2.5e-38 131.6 32.1 3.2e-38 131.3 22.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME80176.1 - 9.3e-26 90.3 47.9 9.3e-26 90.3 33.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME80176.1 - 1.4e-11 43.6 14.5 1.4e-11 43.6 10.0 3.6 3 2 1 4 4 4 1 Sugar (and other) transporter DUF2614 PF11023.3 EME80176.1 - 6.7 6.5 8.8 0.31 10.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2614) ADH_zinc_N PF00107.21 EME80181.1 - 2.3e-23 82.1 0.0 4.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME80181.1 - 2.9e-17 62.3 0.3 5.4e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Met_10 PF02475.11 EME80181.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EME80181.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME80181.1 - 0.089 13.3 0.0 0.27 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME80181.1 - 0.095 12.0 0.1 0.44 9.8 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase small domain IGR PF09597.5 EME80182.1 - 1.2e-21 76.2 0.0 1.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 EME80183.1 - 2.3e-66 223.5 0.0 2.8e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80183.1 - 6.2e-35 120.5 0.0 8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME80183.1 - 0.0025 16.8 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UPF0086 PF01868.11 EME80186.1 - 1.3e-25 88.8 0.1 2.2e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Glyco_hydro_7 PF00840.15 EME80187.1 - 4.2e-195 648.1 20.1 4.8e-195 647.9 13.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 PNPOx_C PF10590.4 EME80188.1 - 1.2e-20 72.7 3.0 1.2e-20 72.7 2.1 1.8 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EME80188.1 - 2e-18 66.1 0.0 3.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EME80188.1 - 0.015 15.6 0.1 0.035 14.3 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Glyco_hydro_18 PF00704.23 EME80189.1 - 1.6e-12 47.5 1.0 2.1e-12 47.1 0.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CHORD PF04968.7 EME80191.1 - 0.0075 16.4 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 CHORD LepA_C PF06421.7 EME80193.1 - 0.21 11.5 1.9 0.28 11.0 1.3 1.1 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus WD40 PF00400.27 EME80195.1 - 1.8e-80 262.1 23.8 5.2e-13 48.3 0.3 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EME80195.1 - 2.4e-06 26.0 0.7 0.084 10.9 0.0 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EME80195.1 - 6.9e-05 22.6 0.1 2.6 7.7 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EME80195.1 - 0.004 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain TFIIIC_delta PF12657.2 EME80195.1 - 0.0065 16.1 0.1 0.72 9.5 0.0 3.4 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term DUF1652 PF07865.6 EME80195.1 - 0.0075 15.8 0.1 0.15 11.6 0.0 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1652) PD40 PF07676.7 EME80195.1 - 0.019 14.5 1.0 77 3.1 0.0 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EME80195.1 - 0.044 12.5 1.2 5 5.7 0.0 3.2 1 1 1 3 3 3 0 Nup133 N terminal like Fer4_19 PF06902.6 EME80196.1 - 0.14 12.0 14.0 59 3.5 0.0 7.8 1 1 7 8 8 8 0 Divergent 4Fe-4S mono-cluster zf-dskA_traR PF01258.12 EME80196.1 - 1.2 8.9 8.4 45 3.9 0.0 4.5 1 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Ni_hydr_CYTB PF01292.15 EME80197.1 - 0.061 12.7 0.4 0.097 12.0 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Ank_2 PF12796.2 EME80198.1 - 2.7e-07 30.8 1.3 0.00012 22.2 0.1 3.8 3 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EME80198.1 - 6.5e-05 22.8 1.6 0.25 11.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EME80198.1 - 0.00024 21.2 1.6 1.5 9.1 0.0 5.3 3 2 3 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME80198.1 - 0.0034 17.8 0.2 0.047 14.2 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EME80198.1 - 0.014 15.1 0.1 0.66 9.8 0.0 3.4 2 0 0 2 2 2 0 Ankyrin repeat RUN PF02759.14 EME80198.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 RUN domain Ank_2 PF12796.2 EME80199.1 - 9.7e-27 93.1 0.0 2.7e-09 37.2 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EME80199.1 - 9.1e-23 78.8 0.1 2.9e-06 26.8 0.0 4.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EME80199.1 - 5.1e-15 54.0 0.0 2.2e-05 24.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EME80199.1 - 5.8e-14 52.1 0.1 0.0001 22.7 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME80199.1 - 5.5e-13 48.6 0.2 0.0005 20.2 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) DUF4340 PF14238.1 EME80201.1 - 0.043 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) DUF2786 PF10979.3 EME80202.1 - 5.6e-06 25.9 1.1 5.6e-06 25.9 0.7 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2786) KH_1 PF00013.24 EME80204.1 - 7.8e-05 22.2 1.1 7.8e-05 22.2 0.8 2.1 2 0 0 2 2 2 1 KH domain DUF4414 PF14377.1 EME80204.1 - 0.19 11.6 2.8 2.1 8.3 1.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4414) Proteasome PF00227.21 EME80205.1 - 1.1e-29 103.1 0.1 2.1e-29 102.1 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit GCV_T PF01571.16 EME80206.1 - 0.0097 15.2 0.6 3.9 6.7 0.0 2.9 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain Baculo_PEP_C PF04513.7 EME80206.1 - 0.073 12.8 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1116 PF06545.6 EME80206.1 - 0.097 11.7 5.0 2.1 7.3 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1116) HsbA PF12296.3 EME80206.1 - 0.59 9.9 13.5 0.63 9.8 1.3 2.5 1 1 2 3 3 3 0 Hydrophobic surface binding protein A G_glu_transpept PF01019.16 EME80206.1 - 0.63 8.4 13.3 0.17 10.3 1.7 2.3 1 1 1 2 2 2 0 Gamma-glutamyltranspeptidase Pex2_Pex12 PF04757.9 EME80207.1 - 2.6e-40 138.2 6.5 3.6e-40 137.8 4.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EME80207.1 - 4.8e-12 45.4 9.9 8.2e-12 44.7 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME80207.1 - 5.1e-12 45.6 8.8 8.7e-12 44.8 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME80207.1 - 4e-10 39.2 6.2 6.2e-10 38.6 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME80207.1 - 6.2e-10 38.5 7.8 1.1e-09 37.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME80207.1 - 4.6e-08 32.6 6.2 7.8e-08 31.9 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME80207.1 - 1.1e-06 28.4 8.8 1.9e-06 27.6 6.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME80207.1 - 2.9e-05 23.6 2.5 0.00011 21.8 1.8 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EME80207.1 - 0.00016 21.3 2.8 0.0003 20.4 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EME80207.1 - 0.00022 21.2 9.1 0.00077 19.5 6.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 EME80207.1 - 0.003 17.4 0.0 0.0087 15.9 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EME80207.1 - 0.014 14.8 2.3 0.031 13.7 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EME80207.1 - 0.035 13.6 7.7 0.061 12.9 5.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Neuregulin PF02158.10 EME80207.1 - 0.048 12.4 1.4 0.076 11.7 1.0 1.2 1 0 0 1 1 1 0 Neuregulin family zf-Apc11 PF12861.2 EME80207.1 - 0.18 11.6 6.8 0.075 12.8 1.7 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 EME80207.1 - 2.8 7.8 7.3 8.7 6.3 5.1 1.8 1 1 0 1 1 1 0 IBR domain ArfGap PF01412.13 EME80208.1 - 1e-35 122.0 0.0 1e-35 122.0 0.0 2.7 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 EME80208.1 - 8.4e-14 51.6 0.2 2.7e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 PH domain MRC1 PF09444.5 EME80209.1 - 1 9.6 8.2 2.7 8.2 5.7 1.7 1 0 0 1 1 1 0 MRC1-like domain ADH_zinc_N PF00107.21 EME80211.1 - 5e-25 87.5 0.7 8.9e-25 86.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME80211.1 - 3.4e-17 63.5 0.1 1.5e-16 61.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME80211.1 - 2.4e-08 33.7 0.0 7.4e-08 32.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EME80211.1 - 0.00092 18.8 0.2 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 EME80211.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.14 EME80212.1 - 5.3e-53 179.5 0.0 6.9e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME80212.1 - 9.6e-36 123.3 0.0 1.2e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME80212.1 - 1.2e-15 57.1 0.0 3.1e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EME80212.1 - 1.1e-11 44.9 0.0 2.3e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EME80212.1 - 1.4e-08 33.9 0.0 1.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME80212.1 - 2.1e-08 34.3 0.0 2.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME80212.1 - 8.1e-08 31.4 0.0 8.2e-07 28.2 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EME80212.1 - 8.1e-06 25.6 0.0 2.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EME80212.1 - 0.076 13.3 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Acetyltransf_3 PF13302.1 EME80213.1 - 2.8e-24 85.8 0.0 3.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME80213.1 - 0.0001 22.2 0.8 0.024 14.5 0.6 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME80213.1 - 0.0018 18.2 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family AAA PF00004.24 EME80214.1 - 5e-43 146.4 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME80214.1 - 1.1e-07 32.0 0.1 4.5e-06 26.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EME80214.1 - 1.9e-06 27.6 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME80214.1 - 1.9e-06 27.9 0.0 7.6e-06 25.9 0.0 2.0 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EME80214.1 - 2.7e-06 27.5 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EME80214.1 - 7.2e-06 25.2 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EME80214.1 - 0.00022 20.2 0.0 0.00054 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EME80214.1 - 0.00035 20.2 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EME80214.1 - 0.00067 20.4 0.5 0.0025 18.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME80214.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EME80214.1 - 0.0015 17.3 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EME80214.1 - 0.0021 17.9 0.0 0.0063 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EME80214.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EME80214.1 - 0.0031 16.6 0.0 0.0069 15.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EME80214.1 - 0.0033 17.7 0.0 0.0083 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME80214.1 - 0.005 17.0 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EME80214.1 - 0.0052 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EME80214.1 - 0.0072 15.8 0.0 0.026 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EME80214.1 - 0.0095 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME80214.1 - 0.012 15.0 0.1 0.061 12.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EME80214.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME80214.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EME80214.1 - 0.025 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EME80214.1 - 0.026 13.6 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 EME80214.1 - 0.027 14.1 0.0 0.13 11.9 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 EME80214.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EME80214.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein eIF-1a PF01176.14 EME80214.1 - 0.036 13.4 0.2 0.067 12.6 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 NACHT PF05729.7 EME80214.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EME80214.1 - 0.05 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EME80214.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EME80214.1 - 0.094 12.2 0.1 0.32 10.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EME80214.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Enolase_C PF00113.17 EME80215.1 - 2.9e-153 509.0 0.3 4.2e-153 508.5 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EME80215.1 - 1.7e-56 189.8 0.4 3.6e-56 188.7 0.3 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EME80215.1 - 0.00029 20.7 0.2 0.0007 19.5 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EME80215.1 - 0.034 13.0 2.9 0.05 12.5 0.5 2.1 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DNA_ligase_aden PF01653.13 EME80215.1 - 0.047 12.6 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain MR_MLE PF01188.16 EME80215.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain PIR PF00399.14 EME80217.1 - 0.0019 17.4 2.8 1.1 8.6 0.1 2.8 2 0 0 2 2 2 2 Yeast PIR protein repeat zf-TFIIB PF13453.1 EME80217.1 - 0.046 12.9 3.2 0.45 9.7 0.3 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger IBR PF01485.16 EME80217.1 - 0.38 10.6 3.9 9.2 6.2 0.1 2.7 3 0 0 3 3 3 0 IBR domain Cys_knot PF00007.17 EME80217.1 - 0.9 9.6 13.1 12 6.0 4.4 2.9 2 1 1 3 3 3 0 Cystine-knot domain M20_dimer PF07687.9 EME80218.1 - 1.9e-20 72.6 0.1 3.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EME80218.1 - 3.1e-20 72.4 1.4 5.9e-20 71.5 0.9 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EME80218.1 - 0.00019 21.2 0.4 0.0005 19.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Pkinase PF00069.20 EME80219.1 - 1.8e-70 237.0 0.0 2.8e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80219.1 - 1.8e-49 168.1 0.0 3.7e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME80219.1 - 2.3e-05 23.5 0.0 0.00036 19.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PAT1 PF09770.4 EME80219.1 - 0.27 9.4 16.8 0.36 9.0 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EME80219.1 - 0.48 9.7 21.9 0.75 9.1 15.2 1.3 1 0 0 1 1 1 0 Vta1 like PRCC PF10253.4 EME80219.1 - 3.8 8.1 9.7 0.83 10.3 3.7 2.2 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Fungal_trans_2 PF11951.3 EME80220.1 - 9.2e-09 34.3 0.1 1.1e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ecm29 PF13001.2 EME80221.1 - 3.8e-132 441.3 0.5 2.1e-129 432.2 0.0 2.9 2 1 0 3 3 3 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 EME80221.1 - 2.8e-10 40.4 0.8 0.0011 19.3 0.0 6.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EME80221.1 - 1.6e-07 31.5 18.5 0.09 13.2 0.4 10.3 11 0 0 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EME80221.1 - 1.1e-06 28.1 16.2 0.52 10.5 0.0 8.9 11 0 0 11 11 11 4 HEAT repeat CRM1_C PF08767.6 EME80221.1 - 0.079 11.8 0.1 17 4.1 0.0 2.9 3 0 0 3 3 3 0 CRM1 C terminal SnoaL_4 PF13577.1 EME80223.1 - 4.9e-12 45.8 0.7 5.3e-12 45.7 0.5 1.0 1 0 0 1 1 1 1 SnoaL-like domain DUF4366 PF14283.1 EME80225.1 - 0.005 16.2 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Yip1 PF04893.12 EME80225.1 - 0.015 14.7 1.2 0.028 13.9 0.8 1.4 1 0 0 1 1 1 0 Yip1 domain Phage_HK97_TLTM PF06120.6 EME80225.1 - 0.047 13.0 2.1 0.088 12.1 0.1 1.9 2 0 0 2 2 2 0 Tail length tape measure protein Pam17 PF08566.5 EME80225.1 - 0.048 13.3 0.2 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial import protein Pam17 TraT PF05818.7 EME80225.1 - 0.16 11.3 2.7 0.27 10.6 1.8 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein p450 PF00067.17 EME80226.1 - 1.9e-72 244.2 0.0 2.6e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CMD PF02627.15 EME80227.1 - 8.9e-08 31.8 0.1 2.7e-07 30.3 0.0 1.8 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family SSF PF00474.12 EME80229.1 - 5.5e-19 68.1 33.6 8.9e-19 67.3 23.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Vpu PF00558.14 EME80229.1 - 1.1 8.8 3.1 5.9 6.5 2.1 2.3 1 0 0 1 1 1 0 Vpu protein Arylsulfotran_2 PF14269.1 EME80230.1 - 8.6e-33 113.7 0.1 1.4e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME80230.1 - 2.9e-16 59.0 0.2 9.9e-15 53.9 0.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Proteasome PF00227.21 EME80231.1 - 1.7e-28 99.1 0.0 2.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EME80232.1 - 2.3e-20 72.3 0.0 3.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein TPR_MLP1_2 PF07926.7 EME80233.1 - 0.024 14.3 0.8 0.051 13.3 0.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fic_N PF13784.1 EME80233.1 - 0.067 13.0 0.1 0.21 11.4 0.1 1.8 1 0 0 1 1 1 0 Fic/DOC family N-terminal AAA_16 PF13191.1 EME80234.1 - 4.7e-13 49.5 0.8 9.3e-11 42.0 0.1 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME80234.1 - 2.3e-10 40.7 0.0 7e-10 39.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 EME80234.1 - 3.2e-08 33.8 0.0 1e-07 32.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EME80234.1 - 5.9e-07 29.4 0.2 1e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EME80234.1 - 1.1e-05 25.2 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME80234.1 - 0.00046 19.8 0.0 0.003 17.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 EME80234.1 - 0.0025 16.7 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 EME80234.1 - 0.0026 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EME80234.1 - 0.0047 16.5 0.0 0.021 14.4 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Cdc6_C PF09079.6 EME80234.1 - 0.0067 16.1 0.0 0.038 13.7 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal UvrD-helicase PF00580.16 EME80234.1 - 0.0072 15.6 0.1 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_18 PF13238.1 EME80234.1 - 0.008 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME80234.1 - 0.0084 16.9 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.4 EME80234.1 - 0.012 14.5 0.2 0.052 12.4 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.1 EME80234.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EME80234.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA12 PF10443.4 EME80234.1 - 0.018 13.5 0.0 0.038 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA12 protein NTPase_1 PF03266.10 EME80234.1 - 0.028 14.1 0.0 0.078 12.6 0.0 1.8 2 0 0 2 2 1 0 NTPase AAA_30 PF13604.1 EME80234.1 - 0.037 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EME80234.1 - 0.038 13.4 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EME80234.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.7 EME80234.1 - 0.057 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 EME80234.1 - 0.065 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein PIF1 PF05970.9 EME80234.1 - 0.066 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase TIP49 PF06068.8 EME80234.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus MMR_HSR1 PF01926.18 EME80234.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EME80234.1 - 0.11 13.0 0.1 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 EME80234.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LysM PF01476.15 EME80236.1 - 2.9e-32 110.2 3.2 2.5e-13 49.6 0.1 3.2 3 0 0 3 3 3 3 LysM domain OapA PF04225.7 EME80236.1 - 0.0063 16.3 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 2 Opacity-associated protein A LysM-like domain DUF4124 PF13511.1 EME80236.1 - 5.2 7.1 9.4 91 3.2 6.5 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4124) adh_short_C2 PF13561.1 EME80237.1 - 6.6e-17 62.0 0.1 8e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME80237.1 - 1.1e-06 28.7 0.1 1.4e-06 28.3 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME80237.1 - 0.0002 21.0 0.1 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME80237.1 - 0.0074 16.3 0.9 0.02 14.9 0.6 1.8 1 1 0 1 1 1 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 EME80237.1 - 0.096 12.0 0.0 0.87 8.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family IDO PF01231.13 EME80238.1 - 1.6e-40 138.8 0.0 2.8e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GFA PF04828.9 EME80239.1 - 8.5e-22 76.9 0.5 1.2e-21 76.4 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HECA PF15353.1 EME80239.1 - 0.0062 16.2 2.4 0.0097 15.5 1.7 1.4 1 1 0 1 1 1 1 Headcase protein family homologue Zn_ribbon_recom PF13408.1 EME80239.1 - 0.083 13.1 0.0 0.083 13.1 0.0 2.6 2 1 0 3 3 3 0 Recombinase zinc beta ribbon domain Methyltransf_11 PF08241.7 EME80241.1 - 1.5e-23 83.0 0.0 3e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME80241.1 - 7.9e-21 74.2 0.0 1.5e-20 73.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME80241.1 - 3.6e-13 49.1 0.0 6.2e-13 48.3 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME80241.1 - 6.7e-12 45.7 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME80241.1 - 2.2e-11 43.9 0.0 4.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80241.1 - 5.7e-11 42.9 0.0 8.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME80241.1 - 2.7e-10 40.2 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME80241.1 - 1.4e-08 34.3 0.0 2.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME80241.1 - 6.8e-06 26.1 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EME80241.1 - 9.8e-06 24.7 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.11 EME80241.1 - 5.7e-05 21.6 0.1 9.5e-05 20.9 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 EME80241.1 - 7.5e-05 21.7 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.7 EME80241.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 EME80241.1 - 0.0018 17.6 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.1 EME80241.1 - 0.0036 16.9 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EME80241.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase GCD14 PF08704.5 EME80241.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EME80241.1 - 0.029 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 EME80241.1 - 0.039 13.2 0.2 7.6 5.7 0.0 2.6 2 1 0 3 3 3 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 EME80241.1 - 0.057 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EME80241.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cytochrom_C1 PF02167.10 EME80242.1 - 1.8e-80 269.7 0.0 2.3e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EME80242.1 - 0.0094 16.0 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III FAD_binding_3 PF01494.14 EME80243.1 - 6.5e-20 71.4 0.0 2.1e-12 46.8 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME80243.1 - 1e-07 31.8 0.4 2.5e-07 30.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME80243.1 - 6e-05 22.1 1.5 0.0012 17.8 0.6 2.6 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME80243.1 - 0.00052 20.3 0.1 0.002 18.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME80243.1 - 0.0007 18.5 0.1 0.0013 17.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME80243.1 - 0.00087 19.2 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME80243.1 - 0.004 17.2 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME80243.1 - 0.014 14.5 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 EME80243.1 - 0.026 14.3 0.2 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.9 EME80243.1 - 0.026 13.8 0.3 0.079 12.3 0.2 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EME80243.1 - 0.086 11.4 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EME80243.1 - 0.13 12.0 0.1 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EME80243.1 - 0.14 10.9 1.1 0.24 10.1 0.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EME80244.1 - 2.2e-32 112.5 0.0 3.1e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME80244.1 - 1.9e-09 37.7 0.0 3.3e-07 30.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME80244.1 - 1.4e-06 27.4 0.0 0.00018 20.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EME80244.1 - 7.5e-05 22.8 0.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_16 PF10294.4 EME80244.1 - 0.019 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Metallophos PF00149.23 EME80245.1 - 5e-07 29.3 1.6 2e-06 27.3 1.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME80245.1 - 2.3e-06 27.5 0.1 5.2e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GAS PF13851.1 EME80246.1 - 0.0013 17.9 8.8 0.0013 17.9 6.1 2.0 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 EME80246.1 - 0.0087 15.6 7.9 0.1 12.1 0.0 2.3 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Med28 PF11594.3 EME80246.1 - 0.041 14.1 1.5 0.3 11.3 1.0 2.3 1 1 0 1 1 1 0 Mediator complex subunit 28 ATG16 PF08614.6 EME80246.1 - 0.5 10.1 17.0 1.8 8.3 11.8 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HSP70 PF00012.15 EME80246.1 - 1.4 6.7 9.0 1.8 6.3 6.2 1.2 1 0 0 1 1 1 0 Hsp70 protein FUSC PF04632.7 EME80246.1 - 3.4 5.9 9.5 4.7 5.5 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cortex-I_coil PF09304.5 EME80246.1 - 7 6.7 13.4 2.5 8.1 6.5 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil HSP70 PF00012.15 EME80247.1 - 2.6e-07 28.9 0.0 3.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Glyco_transf_34 PF05637.7 EME80248.1 - 1.2e-15 57.6 0.0 1.5e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EME80248.1 - 0.0072 15.6 0.2 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF273 AAA_13 PF13166.1 EME80249.1 - 0.093 11.1 5.7 0.12 10.8 4.0 1.0 1 0 0 1 1 1 0 AAA domain CASP_C PF08172.7 EME80249.1 - 0.28 10.1 11.4 0.54 9.2 7.9 1.5 1 1 0 1 1 1 0 CASP C terminal IncA PF04156.9 EME80249.1 - 1.6 8.2 12.6 2.1 7.8 8.7 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EME80249.1 - 1.8 7.5 11.0 2.6 7.0 7.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NatB_MDM20 PF09797.4 EME80250.1 - 2.8e-30 105.2 1.1 3.9e-30 104.7 0.1 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_C53 PF05550.6 EME80250.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 RAMP4 PF06624.7 EME80251.1 - 1.5e-07 30.8 0.0 1.8e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3899 PF13038.1 EME80251.1 - 0.028 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DnaJ PF00226.26 EME80252.1 - 4.3e-13 48.7 0.3 2.3e-12 46.4 0.2 2.1 1 1 0 1 1 1 1 DnaJ domain Mem_trans PF03547.13 EME80252.1 - 0.25 9.6 1.4 0.71 8.1 0.1 1.9 2 0 0 2 2 2 0 Membrane transport protein PRA1 PF03208.14 EME80253.1 - 2.2e-40 137.5 5.0 2.5e-40 137.3 3.4 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF975 PF06161.6 EME80253.1 - 0.013 15.2 2.4 0.015 15.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF427 PF04248.7 EME80255.1 - 4.1e-37 125.7 0.5 6.9e-30 102.5 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) UPF0086 PF01868.11 EME80255.1 - 0.017 14.7 0.0 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function UPF0086 zf-C3HC4_4 PF15227.1 EME80256.1 - 2.6e-10 40.0 11.4 7.4e-10 38.5 6.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EME80256.1 - 2.7e-09 36.8 11.4 3e-09 36.7 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME80256.1 - 3.1e-09 36.3 8.7 3.1e-09 36.3 6.0 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME80256.1 - 3.5e-09 36.3 6.7 3.5e-09 36.3 4.6 2.4 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 EME80256.1 - 9.6e-08 31.6 8.0 9.6e-08 31.6 5.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME80256.1 - 1.9e-07 30.6 4.0 3.3e-07 29.8 2.1 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EME80256.1 - 3.6e-07 29.7 9.4 3.7e-07 29.7 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME80256.1 - 0.0028 17.4 1.4 0.0028 17.4 1.0 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EME80256.1 - 0.0029 17.3 2.5 0.0029 17.3 1.7 2.3 2 1 0 2 2 2 1 zf-RING of BARD1-type protein RecR PF02132.10 EME80256.1 - 0.0062 15.9 2.9 2.2 7.8 0.0 3.4 3 0 0 3 3 3 1 RecR protein zf-Nse PF11789.3 EME80256.1 - 0.016 14.7 3.1 0.016 14.7 2.2 1.6 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EME80256.1 - 0.033 14.2 5.9 0.033 14.2 4.1 2.4 2 1 1 3 3 2 0 RING-H2 zinc finger UPF0547 PF10571.4 EME80256.1 - 0.15 11.8 0.5 0.15 11.8 0.3 3.6 4 1 0 4 4 3 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.1 EME80256.1 - 0.15 11.6 11.4 4 7.0 6.0 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Elf1 PF05129.8 EME80256.1 - 0.23 11.1 6.0 2.7 7.7 0.1 3.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like PhnA_Zn_Ribbon PF08274.7 EME80256.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.0 4 0 0 4 4 3 0 PhnA Zinc-Ribbon zf-RING_3 PF14369.1 EME80256.1 - 0.49 10.4 9.8 0.096 12.6 1.1 2.8 3 0 0 3 3 3 0 zinc-finger zf-4CXXC_R1 PF10497.4 EME80256.1 - 0.64 10.1 9.3 0.79 9.8 4.7 2.2 2 1 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 OrfB_Zn_ribbon PF07282.6 EME80256.1 - 0.65 9.6 0.0 0.65 9.6 0.0 3.8 3 1 2 5 5 5 0 Putative transposase DNA-binding domain DZR PF12773.2 EME80256.1 - 1.6 8.6 10.7 77 3.2 0.0 3.2 2 1 0 2 2 2 0 Double zinc ribbon GAGA PF09237.6 EME80256.1 - 2.9 7.5 6.9 0.46 10.1 1.0 2.3 3 0 0 3 3 2 0 GAGA factor C1_4 PF07975.7 EME80256.1 - 2.9 7.9 7.2 8.3 6.4 1.4 3.0 3 0 0 3 3 3 0 TFIIH C1-like domain IBR PF01485.16 EME80256.1 - 3.4 7.6 13.1 4.7 7.1 0.4 3.4 1 1 1 2 2 2 0 IBR domain DUF164 PF02591.10 EME80256.1 - 3.9 7.3 6.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Putative zinc ribbon domain FYVE PF01363.16 EME80256.1 - 7.3 6.5 11.9 2 8.3 4.6 2.5 2 1 1 3 3 3 0 FYVE zinc finger Evr1_Alr PF04777.8 EME80259.1 - 7.5e-29 99.4 0.3 1.4e-28 98.5 0.2 1.5 1 1 0 1 1 1 1 Erv1 / Alr family Aminotran_4 PF01063.14 EME80260.1 - 1.4e-22 80.2 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV EBV-NA3 PF05009.7 EME80261.1 - 0.0016 17.7 0.1 0.0023 17.2 0.1 1.2 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Shigella_OspC PF06128.6 EME80262.1 - 0.022 14.2 0.0 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein Pex14_N PF04695.8 EME80263.1 - 0.011 15.8 5.6 0.011 15.8 3.9 2.7 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATP-grasp_4 PF13535.1 EME80264.1 - 8.3e-05 22.3 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EME80264.1 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain MFS_1 PF07690.11 EME80266.1 - 0.00046 19.0 23.3 0.011 14.4 1.2 3.3 1 1 1 3 3 3 2 Major Facilitator Superfamily PepSY_TM_1 PF13172.1 EME80266.1 - 3.9 7.3 5.8 0.67 9.7 0.4 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix Peptidase_M14 PF00246.19 EME80267.1 - 5.1e-14 52.5 0.0 8.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Hexapep PF00132.19 EME80268.1 - 3.8e-06 26.1 4.8 0.00042 19.6 0.2 2.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EME80268.1 - 8.4e-05 22.6 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EME80268.1 - 0.0026 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EME80268.1 - 1.3 8.6 6.9 0.29 10.7 0.7 2.7 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase HSA PF07529.8 EME80272.1 - 7.8e-14 51.2 10.0 7.8e-14 51.2 6.9 5.2 5 1 1 6 6 6 1 HSA Myb_DNA-bind_6 PF13921.1 EME80272.1 - 9.9e-11 41.5 2.8 9.9e-11 41.5 1.9 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain WD40 PF00400.27 EME80273.1 - 6.5e-18 63.8 0.0 4.9e-05 23.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME80273.1 - 0.0011 17.7 0.0 5.7 5.5 0.0 3.1 2 1 1 3 3 3 3 Nup133 N terminal like DMRL_synthase PF00885.14 EME80274.1 - 7.5e-44 148.8 0.0 4.4e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase AAA PF00004.24 EME80275.1 - 2.3e-29 102.2 0.0 3.4e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME80275.1 - 2e-07 31.1 0.2 6.8e-07 29.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EME80275.1 - 5.4e-07 30.4 0.0 1.3e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME80275.1 - 9.9e-07 29.1 0.0 2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME80275.1 - 5.3e-06 26.6 0.0 1.9e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME80275.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME80275.1 - 0.00014 21.9 0.0 0.00034 20.7 0.0 1.7 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 EME80275.1 - 0.00033 20.3 0.1 0.0009 18.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.13 EME80275.1 - 0.00036 20.1 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EME80275.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EME80275.1 - 0.00081 18.8 0.0 0.027 13.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EME80275.1 - 0.0024 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME80275.1 - 0.0033 16.9 0.0 0.0076 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EME80275.1 - 0.0035 17.6 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF2075 PF09848.4 EME80275.1 - 0.0037 16.2 0.0 0.0049 15.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EME80275.1 - 0.0061 16.2 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EME80275.1 - 0.0073 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EME80275.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EME80275.1 - 0.011 15.3 0.1 0.028 13.9 0.0 1.8 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EME80275.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EME80275.1 - 0.013 14.6 0.0 0.074 12.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EME80275.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.21 EME80275.1 - 0.022 14.2 0.0 0.055 12.9 0.0 1.6 1 1 1 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 EME80275.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EME80275.1 - 0.024 14.0 0.0 0.1 12.0 0.0 1.9 1 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EME80275.1 - 0.028 14.1 0.0 1.9 8.1 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase SKI PF01202.17 EME80275.1 - 0.041 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase ATP_bind_1 PF03029.12 EME80275.1 - 0.043 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 EME80275.1 - 0.045 13.3 0.1 0.11 12.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EME80275.1 - 0.047 12.7 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EME80275.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EME80275.1 - 0.05 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EME80275.1 - 0.068 13.4 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EME80275.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EME80275.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ADK PF00406.17 EME80275.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase AAA_13 PF13166.1 EME80275.1 - 0.083 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EME80275.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.5 2 0 0 2 2 1 0 NTPase DUF4462 PF14692.1 EME80275.1 - 0.13 11.4 1.2 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) AAA_24 PF13479.1 EME80275.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3431 PF11913.3 EME80276.1 - 2.8e-61 206.8 0.0 3.2e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF221 PF02714.10 EME80277.1 - 4.5e-90 301.7 18.4 4.5e-90 301.7 12.8 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME80277.1 - 6.3e-44 149.2 0.1 6.3e-44 149.2 0.1 3.6 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EME80277.1 - 4.5e-19 68.7 0.2 7.7e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EME80277.1 - 0.0048 16.8 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATG27 PF09451.5 EME80277.1 - 0.16 11.1 0.1 0.41 9.8 0.1 1.6 1 0 0 1 1 1 0 Autophagy-related protein 27 4HBT PF03061.17 EME80279.1 - 4.2e-09 36.3 0.0 6.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily zf-C3HC4_3 PF13920.1 EME80280.1 - 7.6e-05 22.3 9.8 7.6e-05 22.3 6.8 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FAD_binding_3 PF01494.14 EME80281.1 - 2.3e-20 72.9 2.7 2.8e-16 59.5 0.0 2.7 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 EME80281.1 - 1.1e-06 27.8 4.2 0.0018 17.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase SE PF08491.5 EME80281.1 - 0.0018 17.1 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Trp_halogenase PF04820.9 EME80281.1 - 0.0019 16.9 0.3 0.02 13.5 0.0 2.2 2 1 0 2 2 2 1 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EME80281.1 - 0.0038 16.9 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EME80281.1 - 0.0046 17.0 0.1 0.025 14.6 0.1 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME80281.1 - 0.0095 16.3 0.3 0.81 10.1 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME80281.1 - 0.016 13.7 0.6 1 7.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 EME80281.1 - 0.02 14.8 0.2 0.056 13.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME80281.1 - 0.041 12.7 0.6 0.085 11.6 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EME80281.1 - 0.055 13.2 0.2 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME80281.1 - 0.18 10.6 0.8 0.51 9.2 0.5 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Methyltransf_11 PF08241.7 EME80282.1 - 4.2e-14 52.8 0.1 6.7e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80282.1 - 2.1e-11 44.3 0.1 3.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME80282.1 - 9.2e-10 38.4 0.0 1.5e-09 37.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME80282.1 - 2.6e-09 36.8 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME80282.1 - 2.5e-08 33.3 0.0 3.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME80282.1 - 5.3e-07 30.0 0.0 8.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME80282.1 - 2.8e-05 24.1 0.1 5.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EME80282.1 - 0.00019 20.8 0.2 0.00028 20.3 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 EME80282.1 - 0.0002 21.6 0.1 0.00037 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME80282.1 - 0.0003 20.2 0.1 0.00053 19.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EME80282.1 - 0.00096 18.2 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EME80282.1 - 0.0016 17.3 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase FtsJ PF01728.14 EME80282.1 - 0.014 15.3 0.1 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EME80282.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0180 PF03698.8 EME80282.1 - 0.078 12.8 0.3 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF3197 PF11432.3 EME80282.1 - 0.083 12.8 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) LSM PF01423.17 EME80283.1 - 1.4e-19 69.3 0.0 1.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EME80283.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain UnbV_ASPIC PF07593.7 EME80283.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 ASPIC and UnbV Trm112p PF03966.11 EME80284.1 - 8.9e-14 51.6 0.1 1.3e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zf-met PF12874.2 EME80285.1 - 7.4e-15 54.5 34.4 5.1e-05 23.3 0.3 6.9 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME80285.1 - 2.4e-14 52.9 36.5 9.9e-05 22.3 0.3 6.8 7 1 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EME80285.1 - 1.6e-09 37.4 34.7 0.076 13.3 0.1 7.6 6 1 1 7 7 7 6 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EME80285.1 - 2.2e-09 37.3 33.2 0.024 14.7 0.6 6.8 1 1 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EME80285.1 - 7.7e-07 29.1 40.8 0.041 14.2 0.1 7.8 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-Di19 PF05605.7 EME80285.1 - 0.037 14.1 0.4 0.037 14.1 0.2 4.8 4 2 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EME80285.1 - 0.24 11.3 38.3 0.38 10.7 0.9 7.4 7 1 0 7 7 7 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME80285.1 - 1.7 9.0 33.7 3.4 8.1 0.8 7.4 7 1 0 7 7 7 0 Zinc-finger double domain Rad50_zn_hook PF04423.9 EME80285.1 - 5.4 6.5 7.8 4.5 6.8 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif Herpes_capsid PF06112.6 EME80286.1 - 7.1 6.6 7.0 8.2 6.4 4.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HsbA PF12296.3 EME80287.1 - 1.4e-12 47.5 11.5 2.7e-12 46.6 7.2 1.9 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DAO PF01266.19 EME80288.1 - 2.8e-46 158.0 2.2 3.3e-46 157.8 1.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME80288.1 - 1.3e-06 28.6 0.0 0.0073 16.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME80288.1 - 0.00083 19.1 0.5 0.0074 16.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME80288.1 - 0.00096 18.1 0.0 0.0025 16.8 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EME80288.1 - 0.0012 18.8 0.1 0.0034 17.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME80288.1 - 0.0046 16.8 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME80288.1 - 0.015 14.3 0.0 0.049 12.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Fungal_trans PF04082.13 EME80289.1 - 3e-10 39.4 0.2 5.2e-10 38.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME80289.1 - 2.1e-09 37.1 15.4 3.8e-09 36.3 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HsbA PF12296.3 EME80290.1 - 2.8e-25 88.5 1.6 3.4e-25 88.3 1.1 1.0 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Sugar_tr PF00083.19 EME80291.1 - 1.1e-15 57.2 8.3 7e-15 54.5 2.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Glyco_hydro_32N PF00251.15 EME80292.1 - 8.4e-45 153.4 0.0 1.3e-44 152.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EME80292.1 - 1.4e-08 34.9 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PMM PF03332.8 EME80293.1 - 4.7e-100 333.6 0.1 5.5e-100 333.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EME80293.1 - 0.00015 21.4 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EME80293.1 - 0.012 14.6 0.1 0.018 14.1 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Hydrolase PF00702.21 EME80293.1 - 0.029 14.7 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-met PF12874.2 EME80294.1 - 0.028 14.6 0.1 0.057 13.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_3 PF13878.1 EME80294.1 - 0.081 12.5 0.3 6.1 6.4 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CDC45 PF02724.9 EME80294.1 - 0.19 9.7 4.7 0.22 9.5 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EME80294.1 - 0.54 8.1 8.1 0.53 8.1 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EME80294.1 - 1.4 8.6 6.9 2.3 7.8 4.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Herpes_LMP1 PF05297.6 EME80294.1 - 4 6.2 13.0 6.1 5.6 9.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Polyoma_lg_T_C PF06431.6 EME80294.1 - 4.4 5.8 6.5 8.9 4.8 4.5 1.4 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus BH4 PF02180.12 EME80295.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 PDR_CDR PF06422.7 EME80298.1 - 0.032 13.9 0.8 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 CDR ABC transporter PSDC PF12588.3 EME80298.1 - 0.17 11.4 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 Phophatidylserine decarboxylase CMAS PF02353.15 EME80299.1 - 1.5e-60 204.6 0.0 1.9e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EME80299.1 - 4.8e-12 45.9 0.0 7.8e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME80299.1 - 2.2e-07 31.2 0.0 4.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME80299.1 - 0.0052 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80299.1 - 0.02 15.4 0.0 0.052 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EME80299.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EME80299.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME80299.1 - 0.055 12.8 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EME80299.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EME80299.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EME80299.1 - 0.14 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MutS_V PF00488.16 EME80300.1 - 4.3e-75 252.1 0.5 6.9e-75 251.4 0.4 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME80300.1 - 9.5e-37 126.7 1.1 9.5e-37 126.7 0.8 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EME80300.1 - 7.7e-10 38.9 0.1 1.9e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EME80300.1 - 2.8e-06 27.3 0.0 2.8e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 MutS family domain IV Na_Ca_ex PF01699.19 EME80301.1 - 4.4e-44 149.4 38.9 4.3e-24 84.7 10.0 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.9 EME80302.1 - 3.1e-212 707.0 0.7 3.6e-212 706.8 0.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF1903 PF08991.5 EME80303.1 - 4.8e-05 23.4 2.7 6.7e-05 22.9 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EME80303.1 - 0.00019 21.2 3.4 0.0008 19.2 2.3 2.0 1 1 1 2 2 2 1 CHCH domain COX6B PF02297.12 EME80303.1 - 0.0097 15.9 5.6 0.0097 15.9 3.9 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EME80303.1 - 0.045 13.5 5.4 0.53 10.1 0.7 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Aldo_ket_red PF00248.16 EME80303.1 - 0.14 10.9 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family UPF0203 PF05254.7 EME80303.1 - 0.36 10.7 3.3 1.7 8.5 2.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) E1-E2_ATPase PF00122.15 EME80304.1 - 1.5e-65 220.4 11.6 1.8e-65 220.2 3.6 2.7 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME80304.1 - 1e-45 155.4 5.4 1e-45 155.4 3.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME80304.1 - 4.6e-34 118.7 0.0 4.8e-33 115.3 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME80304.1 - 8.4e-22 76.9 0.1 1.8e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EME80304.1 - 8.1e-21 73.2 0.0 2.6e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EME80304.1 - 9.9e-18 64.9 0.0 3.3e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME80304.1 - 5.4e-10 39.2 1.1 2.1e-06 27.4 0.7 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME80304.1 - 0.0038 17.4 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF1640 PF07798.6 EME80305.1 - 1.9e-65 220.1 8.7 2.3e-65 219.9 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HCaRG PF07258.9 EME80305.1 - 0.036 13.6 3.4 0.068 12.7 0.0 2.4 2 1 0 2 2 2 0 HCaRG protein His_kinase PF06580.8 EME80305.1 - 0.3 11.0 3.7 1.8 8.5 0.0 2.5 3 0 0 3 3 3 0 Histidine kinase Syntaxin PF00804.20 EME80305.1 - 0.9 9.7 9.7 1.1 9.4 5.7 2.0 1 1 0 1 1 1 0 Syntaxin DUF3602 PF12223.3 EME80306.1 - 7.3e-15 55.1 17.3 1.6e-14 54.0 1.2 3.0 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) PAPA-1 PF04795.7 EME80309.1 - 1.3e-21 77.1 4.4 1.3e-21 77.1 3.0 3.4 3 0 0 3 3 3 1 PAPA-1-like conserved region Glyco_hydro_72 PF03198.9 EME80310.1 - 1.5e-103 346.1 0.1 2.1e-103 345.6 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EME80310.1 - 0.00037 19.7 0.1 0.0014 17.9 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EME80310.1 - 0.0021 17.0 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4434 PF14488.1 EME80310.1 - 0.042 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) lci PF12197.3 EME80310.1 - 4 7.1 6.4 0.49 10.0 0.2 2.6 3 0 0 3 3 3 0 Bacillus cereus group antimicrobial protein DUF3645 PF12359.3 EME80311.1 - 0.0015 17.5 0.9 0.0023 16.9 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Rad60-SLD PF11976.3 EME80314.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NMO PF03060.10 EME80315.1 - 3.7e-73 246.5 0.6 4.5e-73 246.2 0.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EME80315.1 - 3.8e-07 29.3 0.2 9.5e-07 28.0 0.2 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EME80315.1 - 0.00064 18.6 2.3 0.00098 18.0 1.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TIM-br_sig_trns PF09370.5 EME80315.1 - 0.059 12.4 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein DUF3173 PF11372.3 EME80315.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) PEP-utilizers PF00391.18 EME80315.1 - 0.12 11.9 0.8 0.29 10.7 0.6 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Methyltransf_12 PF08242.7 EME80316.1 - 5.5e-16 58.8 0.0 1.4e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME80316.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME80316.1 - 1.4e-09 38.2 0.0 3.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME80316.1 - 2.4e-09 37.5 0.0 6.9e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80316.1 - 4.9e-09 36.7 0.0 9.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME80316.1 - 1.5e-07 31.1 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME80316.1 - 1.2e-06 28.4 0.0 2.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME80316.1 - 3.5e-05 23.2 0.0 8.1e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EME80316.1 - 0.00017 20.7 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EME80316.1 - 0.013 16.2 0.0 0.027 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EME80316.1 - 0.029 13.3 0.0 0.32 9.9 0.0 2.1 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 EME80316.1 - 0.052 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Glypican PF01153.14 EME80317.1 - 0.074 11.6 0.3 0.11 11.1 0.2 1.3 1 0 0 1 1 1 0 Glypican FLO_LFY PF01698.11 EME80317.1 - 0.12 11.2 2.2 0.17 10.6 1.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2477 PF10631.4 EME80317.1 - 0.5 10.5 5.0 0.93 9.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Nucleo_P87 PF07267.6 EME80317.1 - 1.1 7.8 4.0 1.8 7.1 2.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.7 EME80317.1 - 2.8 7.6 11.0 4.2 7.0 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 EME80317.1 - 3.2 6.0 12.4 4.5 5.5 8.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sigma70_ner PF04546.8 EME80317.1 - 3.3 7.2 5.0 22 4.5 4.4 1.7 2 1 0 2 2 2 0 Sigma-70, non-essential region bZIP_1 PF00170.16 EME80318.1 - 0.0016 18.3 9.3 0.003 17.4 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME80318.1 - 0.013 15.3 11.8 0.026 14.3 8.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper SR-25 PF10500.4 EME80318.1 - 0.81 9.1 14.7 0.035 13.5 5.6 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MCM PF00493.18 EME80319.1 - 4.3e-130 433.3 0.0 8.6e-130 432.3 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EME80319.1 - 1.6e-29 102.8 0.1 5.6e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME80319.1 - 1.7e-06 27.3 0.0 0.00013 21.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME80319.1 - 6.6e-06 25.8 0.0 1.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EME80319.1 - 0.047 13.1 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 EME80319.1 - 0.092 12.3 0.1 0.36 10.4 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans_2 PF11951.3 EME80320.1 - 0.00016 20.4 0.4 0.00016 20.4 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 EME80322.1 - 3.9e-19 69.5 0.0 1.1e-18 68.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME80322.1 - 2.3e-18 65.7 0.1 1.3e-14 53.3 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME80322.1 - 7.5e-11 41.8 0.0 3.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME80322.1 - 5.4e-08 32.1 0.1 9.4e-06 24.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME80322.1 - 0.00044 20.0 0.2 0.024 14.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EME80322.1 - 0.019 13.9 0.0 0.22 10.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EME80322.1 - 0.063 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pec_lyase_N PF04431.8 EME80322.1 - 0.08 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Pectate lyase, N terminus ATP_bind_4 PF01902.12 EME80323.1 - 2.5e-18 66.2 0.0 1.3e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EME80323.1 - 9.4e-12 44.7 0.0 4.5e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Cellulase-like PF12876.2 EME80325.1 - 0.002 18.5 0.0 0.0063 16.9 0.0 1.8 1 0 0 1 1 1 1 Sugar-binding cellulase-like Acetyltransf_7 PF13508.1 EME80326.1 - 5.3e-09 36.1 0.1 9.9e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME80326.1 - 7e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EME80326.1 - 0.00016 21.6 0.1 0.00029 20.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_C48 PF02902.14 EME80327.1 - 7.6e-18 64.9 0.1 1.7e-17 63.7 0.1 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain INSIG PF07281.7 EME80328.1 - 9.2e-54 181.7 0.8 1.2e-53 181.3 0.5 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) EmrE PF13536.1 EME80328.1 - 0.57 10.3 5.4 1.8 8.7 0.1 2.7 3 0 0 3 3 3 0 Multidrug resistance efflux transporter DUF1469 PF07332.6 EME80328.1 - 1.5 8.6 7.9 0.74 9.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) WD40 PF00400.27 EME80329.1 - 1.8e-33 113.1 37.7 7.7e-08 31.9 1.9 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EME80329.1 - 7.2e-19 67.5 0.3 1.6e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Myb_DNA-bind_6 PF13921.1 EME80330.1 - 1.8e-11 43.9 4.6 0.009 16.1 0.6 4.8 2 2 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME80330.1 - 3.9e-09 36.4 4.8 3.6e-05 23.7 0.5 4.5 5 0 0 5 5 5 2 Myb-like DNA-binding domain DUF433 PF04255.9 EME80330.1 - 0.0077 15.6 0.0 7.8 5.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF433) HTH_38 PF13936.1 EME80330.1 - 0.02 14.4 0.8 1.6 8.3 0.0 3.9 4 1 0 4 4 4 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 EME80330.1 - 0.03 14.2 5.1 0.17 11.8 0.3 3.8 4 1 1 5 5 5 0 Transposase Sigma70_r4_2 PF08281.7 EME80330.1 - 0.031 13.7 0.0 0.38 10.2 0.0 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 AICARFT_IMPCHas PF01808.13 EME80331.1 - 9e-109 363.3 0.0 1.1e-108 363.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EME80331.1 - 6.1e-23 80.5 0.0 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain PPTA PF01239.17 EME80333.1 - 3.2e-44 146.4 10.1 3.3e-10 38.8 0.0 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 EME80333.1 - 0.012 15.7 0.1 2.1 8.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4219 PF13961.1 EME80333.1 - 0.45 10.0 5.6 5.9 6.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) HTH_40 PF14493.1 EME80334.1 - 5.2e-05 23.3 0.0 0.00013 22.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Penicillinase_R PF03965.11 EME80334.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Penicillinase repressor LSM PF01423.17 EME80335.1 - 2.8e-20 71.6 0.0 3.2e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain NAD_binding_10 PF13460.1 EME80336.1 - 2e-09 37.7 0.0 3.8e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME80336.1 - 0.0005 19.3 0.0 0.001 18.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family SHR3_chaperone PF08229.6 EME80338.1 - 8.3e-66 220.6 0.1 1e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Aminotran_5 PF00266.14 EME80339.1 - 2.7e-23 82.3 0.0 1e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EME80339.1 - 1.8e-22 79.2 0.0 4.1e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EME80339.1 - 1.4e-19 69.9 0.0 2.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain zf-CGNR PF11706.3 EME80339.1 - 0.33 10.4 2.9 3.7 7.1 0.0 3.1 3 0 0 3 3 3 0 CGNR zinc finger COesterase PF00135.23 EME80340.1 - 1.2e-73 248.6 0.2 2.7e-73 247.5 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME80340.1 - 6e-09 35.7 0.1 1.3e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.6 EME80342.1 - 4e-16 59.4 5.0 8e-13 48.7 0.3 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.1 EME80343.1 - 1.6e-15 56.5 16.5 1.8e-08 34.2 1.6 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EME80343.1 - 2.7e-07 30.5 33.6 0.0062 16.8 2.5 4.4 5 0 0 5 5 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME80343.1 - 1.2e-06 28.4 21.5 0.021 15.1 3.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME80343.1 - 0.0012 18.9 10.0 0.39 10.9 1.6 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EME80343.1 - 0.0025 17.6 12.6 0.009 15.8 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger Tup_N PF08581.5 EME80343.1 - 0.032 14.4 0.1 0.08 13.1 0.1 1.6 1 0 0 1 1 1 0 Tup N-terminal zf-C2HC_2 PF13913.1 EME80343.1 - 0.47 10.1 5.4 0.15 11.7 0.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EME80343.1 - 0.57 10.3 11.6 0.046 13.8 4.3 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.2 EME80343.1 - 0.63 9.9 6.3 6.4 6.6 4.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.6 EME80343.1 - 0.66 9.6 7.6 0.36 10.4 1.0 2.8 1 1 2 3 3 3 0 GAGA factor zf-CHCC PF10276.4 EME80343.1 - 1.3 8.8 8.2 6.7 6.6 0.2 3.4 4 0 0 4 4 3 0 Zinc-finger domain Zn-ribbon_8 PF09723.5 EME80343.1 - 2.6 8.0 8.8 20 5.2 2.5 3.0 1 1 1 2 2 2 0 Zinc ribbon domain GHMP_kinases_N PF00288.21 EME80344.1 - 3.4e-19 68.6 0.2 2.4e-18 65.9 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME80344.1 - 3.9e-09 36.5 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal IncA PF04156.9 EME80344.1 - 0.015 14.9 0.2 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 IncA protein GalKase_gal_bdg PF10509.4 EME80344.1 - 0.069 12.4 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Galactokinase galactose-binding signature PALP PF00291.20 EME80345.1 - 3.1e-60 203.9 0.1 3.9e-60 203.6 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AMP-binding PF00501.23 EME80346.1 - 4.6e-56 189.9 0.1 5.5e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PDT PF00800.13 EME80346.1 - 0.041 13.4 0.2 0.38 10.2 0.0 2.4 2 1 1 3 3 3 0 Prephenate dehydratase AMP-binding PF00501.23 EME80347.1 - 2.4e-25 88.7 0.0 6e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme HxxPF_rpt PF13745.1 EME80347.1 - 1.2e-07 31.9 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EME80347.1 - 1.9e-07 31.9 0.0 7.6e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_18 PF12847.2 EME80347.1 - 7.8e-06 26.4 0.0 3.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME80347.1 - 1.4e-05 25.0 0.9 6.7e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME80347.1 - 6.4e-05 23.3 0.0 0.00036 20.9 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME80347.1 - 0.00066 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME80347.1 - 0.0007 19.9 0.0 0.0034 17.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME80347.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME80347.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EME80348.1 - 1.2e-44 152.3 0.0 1.9e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EME80348.1 - 3.6e-22 78.5 0.0 5.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EME80348.1 - 7.4e-17 61.3 0.3 1.9e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EME80348.1 - 5.2e-12 46.5 0.0 1.2e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3328 PF11807.3 EME80349.1 - 1.9e-32 112.7 1.4 2.5e-32 112.3 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1961 PF09224.6 EME80350.1 - 0.0025 16.9 2.8 11 5.0 0.0 4.2 1 1 5 6 6 6 5 Domain of unknown function (DUF1961) DUF676 PF05057.9 EME80350.1 - 0.15 11.2 1.3 12 5.1 0.0 3.3 1 1 3 4 4 4 0 Putative serine esterase (DUF676) R3H PF01424.17 EME80351.1 - 2.3e-14 52.7 0.5 5.9e-14 51.5 0.0 1.9 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EME80351.1 - 8.8e-07 28.7 56.9 0.0003 20.6 8.5 13.1 12 2 1 13 13 13 6 NF-X1 type zinc finger PCI PF01399.22 EME80352.1 - 4.9e-12 46.0 0.3 2e-11 44.1 0.1 2.2 2 0 0 2 2 2 1 PCI domain TRADD_N PF09034.5 EME80352.1 - 0.028 14.4 0.1 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 TRADD, N-terminal domain Pro-kuma_activ PF09286.6 EME80354.1 - 2e-24 86.2 0.0 3.9e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME80354.1 - 1.4e-07 30.9 0.0 3.2e-07 29.7 0.0 1.6 1 1 1 2 2 2 1 Subtilase family Phage-tail_3 PF13550.1 EME80355.1 - 0.057 13.2 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative phage tail protein ArfGap PF01412.13 EME80357.1 - 1.1e-19 70.3 0.1 3.1e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 EME80357.1 - 1.9e-06 27.5 0.1 5.6e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain DUF3543 PF12063.3 EME80360.1 - 4.9e-78 261.6 0.4 8.3e-78 260.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EME80360.1 - 9.3e-63 211.7 0.0 1.7e-62 210.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80360.1 - 4.3e-41 140.7 0.0 8.4e-41 139.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME80360.1 - 0.026 14.2 0.1 0.097 12.3 0.1 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EME80360.1 - 0.054 12.4 0.0 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Yos1 PF08571.5 EME80360.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Yos1-like NAD_Gly3P_dh_N PF01210.18 EME80361.1 - 8.7e-47 158.7 0.2 4.6e-46 156.4 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EME80361.1 - 2.3e-43 147.4 0.1 3.7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Malic_M PF03949.10 EME80361.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain F420_oxidored PF03807.12 EME80361.1 - 0.059 13.8 0.0 8.1 6.9 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_4 PF01565.18 EME80362.1 - 1.1e-20 73.4 1.6 2.1e-20 72.5 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME80362.1 - 6.6e-11 41.9 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.13 EME80363.1 - 0.043 12.6 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EME80364.1 - 1.4e-75 254.0 0.2 2.1e-75 253.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME80364.1 - 9.2e-46 156.1 0.2 8e-45 153.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME80364.1 - 1.4e-17 63.4 0.0 2.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF221 PF02714.10 EME80365.1 - 3.2e-93 312.1 10.8 5.2e-93 311.4 7.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME80365.1 - 1.3e-36 125.5 1.9 1.3e-36 125.5 1.3 2.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EME80365.1 - 3.7e-19 68.3 0.1 6.5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EME80365.1 - 2.3e-08 34.4 0.1 5.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) zf-LYAR PF08790.6 EME80366.1 - 1.7e-13 50.0 2.1 4.5e-13 48.6 1.5 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Pkinase PF00069.20 EME80367.1 - 1.3e-40 139.2 0.0 2e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EME80367.1 - 2e-38 131.1 0.0 3.2e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EME80367.1 - 1.4e-22 80.0 0.0 3.2e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME80367.1 - 0.0069 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EME80367.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_L32p PF01783.18 EME80368.1 - 0.1 12.7 0.2 0.22 11.7 0.1 1.5 2 0 0 2 2 2 0 Ribosomal L32p protein family RhoGAP PF00620.22 EME80369.1 - 3.4e-39 133.9 0.2 9.8e-39 132.4 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EME80369.1 - 1.9e-11 44.0 0.0 4.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EME80369.1 - 8.2e-06 26.0 0.0 2.5e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EME80369.1 - 0.072 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Orn_Arg_deC_N PF02784.11 EME80370.1 - 5.4e-76 255.0 0.0 7.6e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME80370.1 - 4.6e-29 100.4 0.1 7.6e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain But2 PF09792.4 EME80371.1 - 1.2e-42 145.0 1.0 1.2e-42 145.0 0.7 2.4 2 1 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_17 PF00332.13 EME80371.1 - 0.00027 20.1 0.7 0.00027 20.1 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 zf-CSL PF05207.8 EME80372.1 - 7e-18 63.8 1.0 9.9e-18 63.4 0.7 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EME80372.1 - 1.7e-12 46.8 0.4 2.5e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Fungal_trans_2 PF11951.3 EME80373.1 - 2e-08 33.2 0.0 2.1e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Autophagy_act_C PF03987.10 EME80375.1 - 2e-13 50.2 0.3 3.4e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 EME80376.1 - 9.2e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME80376.1 - 2.3e-09 36.7 0.0 6.1e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME80376.1 - 1.8e-07 30.9 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3824 PF12868.2 EME80376.1 - 0.017 16.0 8.1 0.03 15.2 5.6 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Limkain-b1 PF11608.3 EME80376.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 MAGE_N PF12440.3 EME80376.1 - 0.85 9.9 9.2 1.7 8.9 6.3 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Mito_fiss_reg PF05308.6 EME80376.1 - 0.85 8.9 5.9 1.3 8.3 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 EME80377.1 - 7.7e-24 82.6 11.7 1.3e-06 28.0 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EME80377.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Gmad1 PF10647.4 EME80377.1 - 0.092 12.1 5.0 3.1 7.1 0.0 3.1 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EME80377.1 - 0.11 12.2 0.2 10 5.9 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nop25 PF09805.4 EME80378.1 - 7.6e-26 90.8 17.2 7.6e-26 90.8 11.9 2.7 1 1 2 3 3 3 1 Nucleolar protein 12 (25kDa) Glyco_transf_20 PF00982.16 EME80378.1 - 0.0096 14.4 0.9 0.014 13.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 DUF2183 PF09949.4 EME80378.1 - 0.1 12.5 0.2 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) MSC PF09402.5 EME80378.1 - 0.61 8.7 8.2 1.3 7.6 5.6 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain ATP-synt_S1 PF05827.7 EME80379.1 - 1.1e-31 110.2 0.1 1.5e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nbs1_C PF08599.5 EME80379.1 - 0.0051 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 DNA damage repair protein Nbs1 DUF3738 PF12543.3 EME80380.1 - 2 7.9 5.5 3.5 7.1 2.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3738) Tropomyosin_1 PF12718.2 EME80381.1 - 2.9e-48 163.3 35.1 3.4e-48 163.1 24.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EME80381.1 - 1.9e-07 30.4 32.2 2e-05 23.8 11.3 2.7 1 1 1 2 2 2 2 Tropomyosin Mod_r PF07200.8 EME80381.1 - 0.00045 20.1 24.2 0.14 12.0 13.0 2.2 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EME80381.1 - 0.002 17.3 28.2 0.0038 16.4 13.9 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 EME80381.1 - 0.009 15.5 34.6 0.011 15.3 9.0 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Myosin_tail_1 PF01576.14 EME80381.1 - 0.013 13.3 29.1 0.016 12.9 20.1 1.1 1 0 0 1 1 1 0 Myosin tail Seryl_tRNA_N PF02403.17 EME80381.1 - 0.02 14.8 25.2 0.54 10.2 1.2 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Striatin PF08232.7 EME80381.1 - 0.031 14.5 23.2 0.22 11.8 5.1 2.1 1 1 1 2 2 2 0 Striatin family DUF3166 PF11365.3 EME80381.1 - 0.032 14.6 16.5 0.15 12.5 6.9 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3166) TMF_TATA_bd PF12325.3 EME80381.1 - 0.06 13.0 24.1 0.27 10.9 12.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EME80381.1 - 0.064 12.1 25.6 0.027 13.4 12.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 EME80381.1 - 0.068 12.7 25.1 0.49 9.9 4.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.3 EME80381.1 - 0.089 12.6 30.0 0.14 12.0 6.8 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EME80381.1 - 0.15 11.9 28.0 0.63 9.8 6.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2458 PF10454.4 EME80381.1 - 0.16 11.8 18.5 1.4 8.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) APG6 PF04111.7 EME80381.1 - 0.18 10.8 33.1 0.93 8.4 10.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EME80381.1 - 0.19 11.5 35.8 0.08 12.7 10.3 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EME80381.1 - 0.2 11.6 31.1 0.84 9.6 0.4 4.9 1 1 4 5 5 5 0 bZIP transcription factor BLOC1_2 PF10046.4 EME80381.1 - 0.25 11.5 19.2 0.1 12.7 3.6 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Orbi_VP5 PF00901.12 EME80381.1 - 0.29 9.3 15.0 0.34 9.0 10.4 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 EzrA PF06160.7 EME80381.1 - 0.29 9.2 23.1 0.27 9.3 2.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA NABP PF07990.7 EME80381.1 - 0.3 10.3 5.5 0.32 10.2 3.8 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Filament PF00038.16 EME80381.1 - 0.36 10.2 26.3 1 8.7 18.2 1.6 1 1 0 1 1 1 0 Intermediate filament protein RdRP_4 PF02123.11 EME80381.1 - 0.4 9.3 7.4 0.5 9.0 5.2 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase Herpes_pp85 PF04637.7 EME80381.1 - 0.42 8.8 7.1 0.06 11.6 1.7 1.7 1 1 1 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Rootletin PF15035.1 EME80381.1 - 0.47 10.4 25.4 1.4 8.8 17.5 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 EME80381.1 - 0.48 10.2 29.4 0.035 13.9 2.3 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 EME80381.1 - 0.54 9.8 30.6 0.67 9.5 8.9 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 IFT46_B_C PF12317.3 EME80381.1 - 0.85 8.9 11.0 0.077 12.3 2.2 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal TMP_2 PF06791.8 EME80381.1 - 1.1 8.8 7.9 0.11 12.0 1.5 1.9 1 1 1 2 2 2 0 Prophage tail length tape measure protein Laminin_II PF06009.7 EME80381.1 - 1.1 9.0 18.0 0.14 11.8 3.0 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF3287 PF11690.3 EME80381.1 - 1.3 9.1 12.1 0.22 11.5 1.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DUF4200 PF13863.1 EME80381.1 - 1.5 8.7 34.6 3.8 7.4 8.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4201 PF13870.1 EME80381.1 - 1.6 8.1 24.4 2.1 7.7 5.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Jnk-SapK_ap_N PF09744.4 EME80381.1 - 1.6 8.7 26.3 0.36 10.8 6.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3573 PF12097.3 EME80381.1 - 1.6 7.2 4.7 1.9 7.0 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) IncA PF04156.9 EME80381.1 - 1.6 8.2 28.6 25 4.4 19.8 2.1 1 1 0 1 1 1 0 IncA protein DUF3391 PF11871.3 EME80381.1 - 1.7 8.8 15.2 2.3 8.4 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Fib_alpha PF08702.5 EME80381.1 - 1.7 8.7 17.6 2.3 8.3 4.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KLRAQ PF10205.4 EME80381.1 - 2.4 8.2 19.0 0.44 10.6 6.1 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.7 EME80381.1 - 3 7.6 13.7 4.3 7.1 1.5 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 EME80381.1 - 3.2 4.9 27.5 4.3 4.5 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GP20 PF06810.6 EME80381.1 - 3.8 6.9 30.9 1.1 8.7 9.9 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 LRS4 PF10422.4 EME80381.1 - 4.1 6.6 21.1 16 4.7 14.7 1.8 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DUF3994 PF13159.1 EME80381.1 - 4.3 7.6 13.3 1.7 8.9 0.6 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3994) Syntaxin-6_N PF09177.6 EME80381.1 - 4.9 7.6 15.1 16 6.0 1.3 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.6 EME80381.1 - 6.9 5.2 25.9 3.3 6.2 8.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.6 EME80381.1 - 7.2 4.9 26.4 19 3.6 18.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Cortex-I_coil PF09304.5 EME80381.1 - 7.2 6.6 27.6 7.9 6.5 6.5 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil CDC37_N PF03234.9 EME80381.1 - 8.1 6.7 22.6 27 5.0 15.7 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4140 PF13600.1 EME80381.1 - 9.4 6.7 22.1 4.1 7.9 4.1 2.9 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) N-SET PF11764.3 EME80382.1 - 2.5e-45 154.3 0.1 2.5e-45 154.3 0.1 3.4 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EME80382.1 - 1e-23 82.4 0.0 2.2e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EME80382.1 - 1.5e-22 80.5 0.1 1.5e-22 80.5 0.1 4.0 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 EME80382.1 - 0.00012 21.5 0.2 0.00055 19.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.1 EME80383.1 - 9.8e-05 22.5 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME80384.1 - 2.7e-41 141.3 0.0 6.3e-21 74.1 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME80384.1 - 5.3e-17 62.5 0.1 2.6e-15 57.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME80384.1 - 3.1e-08 33.5 5.8 3.7e-07 30.0 1.3 3.8 3 2 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME80384.1 - 6.2e-08 32.5 0.0 1.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME80384.1 - 1.2e-07 31.8 0.0 1.4e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME80384.1 - 6.6e-06 25.3 0.0 1.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EME80384.1 - 9.1e-06 24.7 0.1 0.0021 17.0 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME80384.1 - 0.00019 20.0 0.0 0.016 13.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 EME80384.1 - 0.00074 18.5 0.7 2.2 7.1 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EME80384.1 - 0.0082 16.5 0.0 0.05 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME80384.1 - 0.013 14.5 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EME80384.1 - 0.025 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EME80384.1 - 0.041 12.9 0.6 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME80384.1 - 0.062 12.1 0.0 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 EME80384.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EME80384.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein SprT-like PF10263.4 EME80385.1 - 7.5e-08 32.1 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 SprT-like family WLM PF08325.5 EME80385.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 WLM domain DIT1_PvcA PF05141.7 EME80387.1 - 1.4e-72 244.3 0.0 1.6e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DAO PF01266.19 EME80388.1 - 3.9e-47 160.8 0.0 4.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME80388.1 - 9.9e-07 29.0 0.1 0.044 13.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME80388.1 - 3.5e-05 23.7 0.3 7.4e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME80388.1 - 0.0074 16.0 0.3 0.071 12.8 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EME80388.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Cadherin PF00028.12 EME80388.1 - 0.12 12.6 0.0 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Cadherin domain DUF3950 PF13132.1 EME80389.1 - 0.0089 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3950) GMC_oxred_N PF00732.14 EME80390.1 - 9.2e-61 205.5 0.0 1.2e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME80390.1 - 1.4e-40 138.9 0.0 2.3e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME80390.1 - 2.6e-11 43.0 0.9 2e-05 23.6 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME80390.1 - 1.2e-08 34.3 1.0 8.1e-05 21.6 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME80390.1 - 6.7e-08 32.8 0.0 0.0038 17.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME80390.1 - 6.7e-06 26.1 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME80390.1 - 1.2e-05 25.2 0.5 5.4e-05 23.1 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME80390.1 - 0.00072 19.9 0.4 0.13 12.6 0.3 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME80390.1 - 0.00086 18.3 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EME80390.1 - 0.0016 16.9 1.0 0.01 14.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EME80390.1 - 0.0019 17.1 0.3 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EME80390.1 - 0.007 15.4 0.1 0.038 13.0 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EME80390.1 - 0.025 13.6 0.1 0.04 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EME80390.1 - 0.099 12.4 0.2 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EME80390.1 - 0.11 11.1 0.1 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 EME80391.1 - 1.9e-33 115.6 51.7 3.2e-32 111.6 35.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME80391.1 - 2.1e-09 36.5 13.4 2.1e-09 36.5 9.3 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter YrhK PF14145.1 EME80391.1 - 0.013 15.1 6.2 0.028 14.0 1.3 3.3 2 0 0 2 2 2 0 YrhK-like protein tRNA-synt_1b PF00579.20 EME80392.1 - 1.8e-12 47.0 0.0 1.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Ank PF00023.25 EME80393.1 - 5.7e-32 107.9 3.9 1.2e-07 31.1 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EME80393.1 - 1.7e-28 97.9 3.3 1.9e-10 40.6 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME80393.1 - 1.7e-27 95.5 0.5 5.5e-13 49.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EME80393.1 - 4.6e-20 69.6 0.2 8.3e-05 22.4 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EME80393.1 - 1.7e-19 69.7 2.5 1.1e-08 35.3 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) adh_short PF00106.20 EME80395.1 - 1.5e-14 54.2 1.3 7.8e-14 51.9 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME80395.1 - 5.7e-05 22.8 0.5 0.00011 21.9 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EME80395.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME80395.1 - 0.0068 16.1 0.0 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF2810 PF10928.3 EME80395.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) HC2 PF07382.6 EME80396.1 - 0.001 19.0 18.4 0.0012 18.7 12.7 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 RNase_H2-Ydr279 PF09468.5 EME80396.1 - 0.13 11.4 3.5 0.16 11.1 2.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Abhydrolase_6 PF12697.2 EME80398.1 - 3.2e-12 46.8 0.1 3.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME80398.1 - 2.8e-06 27.1 0.1 7.6e-06 25.7 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME80398.1 - 0.002 17.7 0.1 0.14 11.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EME80398.1 - 0.011 15.1 0.1 0.08 12.3 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EME80398.1 - 0.013 15.1 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.6 EME80398.1 - 0.029 14.0 0.0 1.8 8.2 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Gly-zipper_Omp PF13488.1 EME80398.1 - 0.28 10.8 3.0 0.52 9.9 2.1 1.4 1 0 0 1 1 1 0 Glycine zipper PD40 PF07676.7 EME80399.1 - 1.9e-39 132.6 22.2 1.4e-07 31.0 0.1 9.7 9 0 0 9 9 9 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EME80399.1 - 1.5e-09 36.9 5.1 0.063 11.8 0.2 6.1 4 1 1 5 5 5 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.6 EME80399.1 - 0.017 14.7 0.0 11 5.7 0.0 4.0 5 1 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal DUF3748 PF12566.3 EME80399.1 - 0.12 12.2 0.4 74 3.2 0.0 4.5 5 1 0 5 5 5 0 Protein of unknown function (DUF3748) Cuticle_1 PF08140.6 EME80399.1 - 0.14 12.0 0.0 34 4.3 0.0 3.9 4 0 0 4 4 4 0 Crustacean cuticle protein repeat DUF1513 PF07433.6 EME80399.1 - 0.17 10.7 0.1 0.72 8.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.4 EME80399.1 - 0.81 9.0 14.6 47 3.4 0.0 6.9 7 1 1 8 8 8 0 Proteasome subunit A N-terminal signature FAD_binding_3 PF01494.14 EME80400.1 - 2.7e-16 59.5 0.1 6.6e-14 51.7 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME80400.1 - 0.003 17.5 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EME80400.1 - 0.085 11.6 0.0 0.22 10.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Bax1-I PF01027.15 EME80401.1 - 1.1e-48 165.5 30.9 1.3e-48 165.3 21.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2910 PF11139.3 EME80401.1 - 0.022 13.9 0.1 0.022 13.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2910) Spore_YhaL PF14147.1 EME80401.1 - 0.078 12.4 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 Sporulation protein YhaL Orbi_NS3 PF01616.11 EME80401.1 - 0.099 11.5 0.7 0.85 8.5 0.2 2.2 2 0 0 2 2 2 0 Orbivirus NS3 TMEM141 PF15110.1 EME80401.1 - 1.1 9.5 6.8 0.12 12.6 1.1 2.0 2 0 0 2 2 2 0 TMEM141 protein family DUF2678 PF10856.3 EME80401.1 - 1.5 8.5 5.6 0.44 10.2 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2678) Pro-kuma_activ PF09286.6 EME80403.1 - 5.1e-45 153.0 0.1 1.6e-42 144.9 0.0 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME80403.1 - 6.9e-06 25.4 2.4 1.1e-05 24.7 1.6 1.3 1 0 0 1 1 1 1 Subtilase family Haemolytic PF01809.13 EME80404.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Haemolytic domain bact-PGI_C PF10432.4 EME80404.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region DUF3425 PF11905.3 EME80405.1 - 5.7e-14 52.1 0.5 1.4e-12 47.6 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) zf-C2HC_2 PF13913.1 EME80406.1 - 2.3e-05 23.8 1.0 0.064 12.9 0.0 3.6 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EME80406.1 - 0.00012 22.2 13.6 0.63 10.5 1.8 5.3 4 1 1 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EME80406.1 - 0.00036 20.6 0.5 0.00036 20.6 0.4 3.7 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EME80406.1 - 0.00038 20.5 3.2 0.00038 20.5 2.2 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME80406.1 - 0.002 18.2 3.0 0.0096 16.0 0.3 3.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EME80406.1 - 0.003 17.7 20.2 0.37 11.2 0.1 5.4 5 1 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME80406.1 - 0.0075 16.5 0.2 0.0075 16.5 0.1 5.1 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EME80406.1 - 0.97 9.4 20.3 0.4 10.6 0.3 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger GOLD_2 PF13897.1 EME80408.1 - 0.45 10.7 1.9 1.1 9.5 1.3 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF724 PF05266.9 EME80409.1 - 0.25 10.9 31.9 0.071 12.7 9.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) PAS_9 PF13426.1 EME80409.1 - 0.25 11.7 1.1 0.45 10.9 0.1 1.9 2 0 0 2 2 2 0 PAS domain ATG16 PF08614.6 EME80409.1 - 0.34 10.6 33.9 0.44 10.3 1.2 3.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF4239 PF14023.1 EME80409.1 - 1.2 8.4 3.3 2.9 7.2 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Fib_alpha PF08702.5 EME80409.1 - 3.5 7.7 13.2 9.6 6.3 2.3 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Peptidase_M19 PF01244.16 EME80411.1 - 1.9e-95 319.4 0.0 2.2e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ilm1 PF10311.4 EME80412.1 - 9.2e-38 129.3 3.1 1.2e-37 128.9 2.2 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4357 PF14267.1 EME80412.1 - 0.056 13.0 0.0 8 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) HMGL-like PF00682.14 EME80415.1 - 6.9e-71 238.6 0.9 1.1e-70 237.9 0.6 1.3 1 0 0 1 1 1 1 HMGL-like Peptidase_C47 PF05543.8 EME80415.1 - 0.0075 15.6 0.0 0.62 9.4 0.0 2.5 2 0 0 2 2 2 2 Staphopain peptidase C47 Trp_syntA PF00290.15 EME80415.1 - 0.026 13.0 0.0 4 5.8 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain GMC_oxred_N PF00732.14 EME80416.1 - 6.9e-61 205.9 0.0 1e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME80416.1 - 4.8e-32 111.2 0.6 4.8e-32 111.2 0.4 2.3 3 1 0 3 3 3 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME80416.1 - 6.2e-06 25.3 0.8 0.092 11.5 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME80416.1 - 2.4e-05 23.4 2.8 0.036 12.9 0.9 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME80416.1 - 0.00088 19.3 0.1 1.9 8.5 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME80416.1 - 0.0032 17.4 0.3 0.011 15.7 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME80416.1 - 0.0069 15.5 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME80416.1 - 0.014 14.3 0.4 0.024 13.5 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EME80416.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EME80416.1 - 0.044 13.6 0.1 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Y_phosphatase3 PF13350.1 EME80419.1 - 2.2e-17 63.7 0.0 4.7e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EME80419.1 - 7.1e-09 35.2 0.1 6.5e-08 32.1 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EME80419.1 - 8.5e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3C PF13348.1 EME80419.1 - 0.00053 20.0 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region DSPc PF00782.15 EME80419.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EME80419.1 - 0.048 12.4 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF3812 PF12757.2 EME80420.1 - 4.1e-31 107.5 20.5 4.1e-31 107.5 14.2 5.6 6 0 0 6 6 6 1 Protein of unknown function (DUF3812) DUF1856 PF08983.5 EME80422.1 - 0.65 10.1 4.7 3.9 7.6 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1856) RNA_pol_L_2 PF13656.1 EME80424.1 - 4.3e-23 80.5 0.0 5.4e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EME80424.1 - 6.1e-09 34.8 0.0 9.1e-09 34.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 EME80424.1 - 0.035 14.1 0.0 0.068 13.2 0.0 1.4 2 0 0 2 2 2 0 Rio2, N-terminal NMO PF03060.10 EME80425.1 - 3.1e-34 118.5 5.3 9.4e-33 113.7 3.7 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EME80425.1 - 1.9e-06 26.9 1.2 2.9e-06 26.3 0.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EME80425.1 - 7.4e-06 25.0 0.0 0.025 13.4 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EME80425.1 - 0.0019 17.2 0.4 0.003 16.5 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF4243 PF14027.1 EME80427.1 - 3.2e-104 348.9 0.1 4.1e-104 348.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) RabGAP-TBC PF00566.13 EME80428.1 - 9.8e-39 133.0 0.0 2e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Adaptin_binding PF10199.4 EME80428.1 - 0.0014 18.9 0.0 0.0024 18.1 0.0 1.4 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Seryl_tRNA_N PF02403.17 EME80428.1 - 6.1 6.9 9.8 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Glyco_hydro_47 PF01532.15 EME80429.1 - 4e-162 539.9 0.6 5.1e-162 539.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ish1 PF10281.4 EME80430.1 - 7.8e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein NTF2 PF02136.15 EME80432.1 - 0.00087 19.6 0.1 0.0077 16.5 0.1 2.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribosomal_L38e PF01781.13 EME80433.1 - 1.3e-32 111.3 1.7 1.7e-32 110.9 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Methyltransf_3 PF01596.12 EME80434.1 - 9e-14 50.9 0.0 1.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EME80434.1 - 7.8e-10 39.5 0.0 1.6e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80434.1 - 0.017 15.6 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EME80434.1 - 0.02 14.2 0.0 0.04 13.2 0.0 1.6 1 1 0 1 1 1 0 Cephalosporin hydroxylase Kinesin PF00225.18 EME80435.1 - 1.2e-97 326.6 0.6 2.3e-97 325.6 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain AAA_22 PF13401.1 EME80435.1 - 0.071 13.2 0.2 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Prenyltrans PF00432.16 EME80437.1 - 7.3e-25 86.2 10.2 1.2e-06 27.9 0.0 5.7 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EME80437.1 - 1.9e-19 70.1 0.0 1e-13 51.6 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME80437.1 - 9.7e-08 31.9 1.9 1.2e-06 28.4 0.2 2.4 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 EME80437.1 - 0.027 13.7 0.0 3 7.0 0.0 2.3 1 1 1 2 2 2 0 A-macroglobulin complement component SNF2_N PF00176.18 EME80438.1 - 1.1e-58 198.4 0.0 2.3e-58 197.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EME80438.1 - 2.3e-09 36.9 13.4 5.2e-09 35.8 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME80438.1 - 9.8e-08 31.8 14.3 3.1e-07 30.3 9.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME80438.1 - 1.5e-07 30.9 9.4 3.1e-07 29.9 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME80438.1 - 1.9e-07 30.6 13.8 3.5e-07 29.7 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME80438.1 - 2e-06 27.4 13.9 4.8e-06 26.1 9.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME80438.1 - 6.7e-05 22.9 5.3 0.00018 21.5 3.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EME80438.1 - 0.0019 17.8 9.4 0.0055 16.3 6.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME80438.1 - 0.042 13.7 12.8 0.086 12.7 8.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Helicase_C PF00271.26 EME80438.1 - 0.047 13.5 0.0 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Gryzun-like PF12742.2 EME80439.1 - 0.074 12.8 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FAM165 PF14981.1 EME80440.1 - 0.08 12.4 0.2 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 FAM165 family EXS PF03124.9 EME80441.1 - 7.7e-76 255.3 12.3 9e-76 255.1 8.5 1.0 1 0 0 1 1 1 1 EXS family DAP3 PF10236.4 EME80444.1 - 6.3e-89 297.9 0.0 8e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2606 PF10794.4 EME80445.1 - 0.003 16.9 0.1 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2606) ATP_bind_4 PF01902.12 EME80445.1 - 0.053 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP-binding region Sod_Fe_C PF02777.13 EME80448.1 - 1.8e-13 50.2 0.2 9.5e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Herpes_Helicase PF02689.9 EME80449.1 - 1.9e-07 29.2 0.0 2.1e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EME80449.1 - 6.7e-07 29.3 0.0 8.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EME80449.1 - 0.001 18.6 0.0 0.0011 18.4 0.0 1.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EME80450.1 - 1.8e-36 125.8 0.0 6.1e-27 94.5 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EME80450.1 - 7.7e-16 58.2 0.0 4.3e-14 52.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EME80450.1 - 5.2e-05 23.4 0.4 0.00025 21.1 0.2 2.0 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EME80450.1 - 0.00012 21.8 1.1 0.014 15.1 0.8 2.3 1 1 0 1 1 1 1 NTPase ArgK PF03308.11 EME80450.1 - 0.00017 20.4 0.1 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein PHD PF00628.24 EME80450.1 - 0.00019 21.0 3.1 0.00019 21.0 2.1 2.4 2 0 0 2 2 2 1 PHD-finger AAA PF00004.24 EME80450.1 - 0.00024 21.3 0.1 0.00081 19.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EME80450.1 - 0.00026 20.6 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EME80450.1 - 0.00043 19.9 0.0 0.54 9.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_32 PF13654.1 EME80450.1 - 0.0017 17.0 0.1 0.0024 16.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EME80450.1 - 0.002 17.4 0.0 0.0045 16.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.9 EME80450.1 - 0.0065 16.1 0.9 0.07 12.7 0.6 2.3 1 1 0 1 1 1 1 Helicase T2SE PF00437.15 EME80450.1 - 0.0077 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.9 EME80450.1 - 0.012 15.3 0.3 0.024 14.3 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EME80450.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 EME80450.1 - 0.017 14.0 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 EME80450.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 EME80450.1 - 0.03 15.1 0.2 0.073 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME80450.1 - 0.033 13.6 0.3 1.5 8.1 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EME80450.1 - 0.036 13.4 1.7 1.1 8.6 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 EME80450.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EME80450.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EME80450.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EME80450.1 - 0.098 12.3 0.1 0.38 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME80450.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EME80450.1 - 0.13 11.9 0.2 3.9 7.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain KTI12 PF08433.5 EME80450.1 - 0.16 11.1 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF3807 PF12720.2 EME80451.1 - 3 7.9 9.4 4.3 7.4 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3807) SEEEED PF14797.1 EME80451.1 - 3.5 7.7 9.0 0.28 11.3 2.1 1.9 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Peptidase_M20 PF01546.23 EME80452.1 - 8.6e-24 84.0 0.1 1.1e-23 83.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME80452.1 - 1.2e-15 57.1 0.0 2.9e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Coat_X PF07552.6 EME80456.1 - 0.1 12.4 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Spore Coat Protein X and V domain EF-hand_4 PF12763.2 EME80457.1 - 7.1e-27 93.1 0.0 7.2e-14 51.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EME80457.1 - 2.4e-06 26.9 0.9 2.4e-06 26.9 0.6 2.1 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.1 EME80457.1 - 2.5e-05 24.3 0.0 0.0033 17.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair DUF1720 PF08226.6 EME80457.1 - 3.5e-05 23.7 173.3 0.00047 20.1 28.6 6.4 4 2 2 6 6 6 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EME80457.1 - 0.0087 15.2 0.0 1.6 8.2 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EME80457.1 - 0.044 13.6 0.2 20 5.4 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain zf-BED PF02892.10 EME80458.1 - 0.061 13.0 1.8 0.1 12.3 1.3 1.4 1 0 0 1 1 1 0 BED zinc finger hDGE_amylase PF14701.1 EME80461.1 - 2.8e-173 576.6 0.0 3.6e-173 576.3 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EME80461.1 - 9.6e-112 373.3 0.2 1.6e-111 372.6 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EME80461.1 - 9.4e-83 277.3 0.0 1.4e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EME80461.1 - 1.6e-26 91.9 0.0 4.1e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EME80461.1 - 2.2e-06 27.2 1.0 4.1e-05 23.1 0.5 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain GCD14 PF08704.5 EME80462.1 - 9e-65 218.5 0.2 2.5e-64 217.1 0.1 1.7 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EME80462.1 - 0.00014 21.8 1.0 0.00026 21.0 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80462.1 - 0.0021 18.6 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EME80462.1 - 0.095 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyco_hydro_31 PF01055.21 EME80463.1 - 3.9e-68 230.3 2.6 2.6e-58 197.8 1.3 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 FAR1 PF03101.10 EME80465.1 - 3.9e-10 40.1 1.9 1.4e-09 38.2 1.3 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain Zn_clus PF00172.13 EME80465.1 - 2e-06 27.6 11.6 3.7e-06 26.7 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBN2_3 PF14244.1 EME80465.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type DUF4611 PF15387.1 EME80465.1 - 1.2 9.3 5.2 16 5.7 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4583 PF15190.1 EME80466.1 - 0.1 12.2 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) PAN_4 PF14295.1 EME80469.1 - 5.2e-06 26.0 7.1 0.011 15.3 0.5 2.8 2 0 0 2 2 2 2 PAN domain Stk19 PF10494.4 EME80471.1 - 1.4e-47 162.1 0.0 8e-47 159.7 0.0 1.8 2 0 0 2 2 2 1 Serine-threonine protein kinase 19 Peptidase_U32 PF01136.14 EME80471.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 DAGAT PF03982.8 EME80472.1 - 5.1e-90 301.1 0.0 6.5e-90 300.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Peptidase_M18 PF02127.10 EME80473.1 - 2.6e-151 504.0 0.0 5.2e-151 503.0 0.0 1.5 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Binary_toxB PF03495.9 EME80473.1 - 0.073 11.6 2.3 0.11 11.0 1.6 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA DUF202 PF02656.10 EME80474.1 - 7.3e-17 61.3 2.1 1.2e-16 60.7 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) zf-MYND PF01753.13 EME80475.1 - 5.9e-12 45.2 13.1 1.3e-11 44.1 8.9 1.7 1 1 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 EME80475.1 - 1.6 6.2 3.9 2.1 5.8 2.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF3716 PF12511.3 EME80475.1 - 2 8.0 9.6 1.4 8.6 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Mnd1 PF03962.10 EME80476.1 - 1.3e-40 139.0 3.7 1.5e-40 138.8 2.5 1.0 1 0 0 1 1 1 1 Mnd1 family Cortex-I_coil PF09304.5 EME80476.1 - 0.025 14.6 2.7 4.4 7.4 0.0 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil Cluap1 PF10234.4 EME80476.1 - 0.44 9.7 4.9 0.62 9.2 0.9 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Fib_alpha PF08702.5 EME80476.1 - 0.62 10.1 3.0 0.74 9.9 0.6 2.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BRE1 PF08647.6 EME80476.1 - 2.1 8.4 6.6 3.7 7.5 2.2 2.7 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Sugar_tr PF00083.19 EME80477.1 - 4.7e-88 295.7 24.2 5.7e-88 295.4 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME80477.1 - 7e-26 90.7 20.5 7e-26 90.7 14.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME80477.1 - 6.2e-08 31.2 3.9 1.3e-07 30.2 2.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SpoVAB PF13782.1 EME80477.1 - 0.022 14.7 5.2 0.77 9.7 1.9 2.8 2 0 0 2 2 2 0 Stage V sporulation protein AB WD40 PF00400.27 EME80478.1 - 7.5e-25 85.8 6.7 1e-07 31.5 0.6 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME80478.1 - 0.0033 16.2 0.2 3 6.5 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like PIF1 PF05970.9 EME80479.1 - 2.4e-12 46.4 0.0 3.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Cauli_VI PF01693.11 EME80479.1 - 0.002 18.0 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_30 PF13604.1 EME80479.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.2 EME80480.1 - 1.9e-14 52.8 7.8 3.1e-12 45.8 0.8 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME80480.1 - 1.3e-12 47.2 2.1 1.3e-12 47.2 1.4 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EME80480.1 - 9.1e-09 34.1 6.3 0.018 14.9 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EME80480.1 - 2.2e-07 29.9 2.9 0.21 11.9 0.1 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EME80480.1 - 0.014 15.3 1.9 2 8.7 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat adh_short PF00106.20 EME80481.1 - 2.6e-18 66.5 0.0 3.7e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME80481.1 - 7e-06 25.8 0.0 1.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME80481.1 - 0.034 13.9 0.0 0.049 13.4 0.0 1.3 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.17 EME80482.1 - 2.4e-24 84.7 0.0 3.5e-18 64.9 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME80482.1 - 4.5e-20 71.3 0.1 8.5e-15 54.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME80482.1 - 2.5e-13 49.6 0.0 3.3e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME80482.1 - 0.12 12.1 0.3 2.2 8.0 0.0 2.9 3 1 0 3 3 3 0 Limkain b1 Nop14 PF04147.7 EME80483.1 - 0.024 12.6 16.4 0.028 12.3 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EME80483.1 - 0.056 12.7 19.3 0.084 12.1 13.4 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EME80483.1 - 0.55 8.6 18.2 0.77 8.1 12.6 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EME80483.1 - 2.1 7.3 19.0 2.5 7.0 13.2 1.2 1 0 0 1 1 1 0 BUD22 TPP_enzyme_C PF02775.16 EME80484.1 - 6.1e-14 51.8 0.0 7.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EME80485.1 - 6.3e-14 51.8 0.2 8e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain RXT2_N PF08595.6 EME80486.1 - 6e-32 110.5 0.1 1.7e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 RXT2-like, N-terminal SRP40_C PF05022.7 EME80487.1 - 3.5e-23 81.8 0.1 7.4e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 SRP40, C-terminal domain SASP PF00269.15 EME80489.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type Fungal_trans_2 PF11951.3 EME80490.1 - 3.6e-63 213.4 0.1 5e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME80490.1 - 4.9e-10 39.1 7.2 9e-10 38.3 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.9 EME80491.1 - 4.4e-62 208.8 13.8 5.1e-62 208.6 9.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Glyco_hydro_35 PF01301.14 EME80492.1 - 5.8e-87 292.0 1.1 8.4e-87 291.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EME80492.1 - 3e-53 179.8 0.3 4.6e-53 179.2 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EME80492.1 - 3.4e-44 149.6 4.1 3.3e-24 85.2 1.7 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EME80492.1 - 9.8e-16 56.9 0.0 2e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 MFS_1 PF07690.11 EME80493.1 - 5.3e-27 94.4 31.2 5.8e-27 94.3 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NMO PF03060.10 EME80494.1 - 1.7e-29 103.0 8.2 1.3e-16 60.6 0.1 3.0 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EME80494.1 - 0.02 13.8 0.1 0.55 9.0 0.0 2.2 1 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain NnrU PF07298.6 EME80495.1 - 0.15 11.4 10.4 0.27 10.6 7.2 1.4 1 0 0 1 1 1 0 NnrU protein Glyco_transf_8 PF01501.15 EME80496.1 - 1.7e-07 30.8 0.0 0.00061 19.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 8 Trypan_PARP PF05887.6 EME80497.1 - 0.59 9.9 5.0 0.61 9.8 3.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 EME80497.1 - 2.3 7.2 9.7 2.8 6.9 6.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Methyltransf_26 PF13659.1 EME80498.1 - 0.096 12.7 0.1 2.4 8.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Extensin_2 PF04554.8 EME80498.1 - 1.7 8.5 6.3 5.3 6.9 1.1 2.3 2 0 0 2 2 2 0 Extensin-like region DUF3716 PF12511.3 EME80505.1 - 4.5e-05 22.9 0.1 9e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chromo PF00385.19 EME80505.1 - 0.043 13.4 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Hydrolase_6 PF13344.1 EME80506.1 - 0.024 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3716 PF12511.3 EME80507.1 - 1.6e-08 34.0 3.7 3.3e-08 33.0 2.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HrpB_C PF08482.5 EME80508.1 - 0.047 13.8 0.6 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal Ribosomal_60s PF00428.14 EME80508.1 - 8.5 6.8 13.0 35 4.8 4.6 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3716 PF12511.3 EME80509.1 - 4.7e-08 32.5 11.8 9.1e-08 31.6 8.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) CFEM PF05730.6 EME80510.1 - 0.32 10.8 14.3 0.93 9.3 9.9 1.8 1 1 1 2 2 2 0 CFEM domain TIL PF01826.12 EME80510.1 - 5.9 7.0 7.7 4.9 7.3 0.8 2.4 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain Peptidase_S28 PF05577.7 EME80511.1 - 2.2e-46 158.3 4.2 6.9e-46 156.6 2.9 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EME80511.1 - 0.00021 21.2 0.1 0.0052 16.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_25 PF01755.12 EME80512.1 - 1.5e-05 24.7 0.0 0.00058 19.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Cu-oxidase_3 PF07732.10 EME80513.1 - 3.1e-38 130.1 1.0 3.1e-38 130.1 0.7 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EME80513.1 - 1.6e-27 96.3 0.6 1.6e-25 89.8 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME80513.1 - 9.8e-26 89.9 9.0 6e-25 87.3 1.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase DUF165 PF02592.10 EME80513.1 - 0.069 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 AhpC-TSA_2 PF13911.1 EME80515.1 - 8.4e-17 61.1 0.0 1.6e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EME80515.1 - 0.0051 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family RPN7 PF10602.4 EME80516.1 - 1.2e-22 80.1 0.3 5.7e-11 42.1 0.0 3.0 2 1 0 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.22 EME80516.1 - 1.9e-09 37.7 0.0 4.5e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain Radial_spoke PF04712.7 EME80518.1 - 0.00056 18.7 3.4 0.00079 18.3 2.3 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein Clr5 PF14420.1 EME80518.1 - 0.00058 19.7 1.1 0.02 14.8 0.1 2.5 2 0 0 2 2 2 1 Clr5 domain PGBA_C PF15437.1 EME80518.1 - 0.0025 17.8 5.7 0.0025 17.8 4.0 2.0 2 0 0 2 2 2 1 Plasminogen-binding protein pgbA C-terminal Nop25 PF09805.4 EME80519.1 - 0.018 15.1 1.5 0.03 14.3 1.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1352 PF07086.7 EME80519.1 - 0.15 11.6 0.3 0.24 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) OPT PF03169.10 EME80520.1 - 1e-116 390.9 41.8 1.2e-116 390.6 29.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4181 PF13789.1 EME80520.1 - 1.5 8.7 9.1 0.37 10.7 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) DUF3093 PF11292.3 EME80520.1 - 1.9 8.3 6.4 0.93 9.2 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Response_reg PF00072.19 EME80521.1 - 7.6e-24 83.8 0.1 1.8e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EME80521.1 - 1.5e-23 82.6 0.0 3.4e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.5 EME80521.1 - 4.2e-07 29.9 0.0 0.0038 17.2 0.0 3.2 2 1 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EME80521.1 - 6.9e-06 26.3 0.0 0.0028 18.0 0.0 3.4 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.1 EME80521.1 - 1.6e-05 24.5 0.0 5.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain HisKA PF00512.20 EME80521.1 - 6e-05 22.9 0.5 0.00033 20.5 0.3 2.3 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EME80521.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS PF00989.19 EME80521.1 - 0.0021 17.7 0.0 0.0078 15.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 EME80521.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PBP PF01161.15 EME80522.1 - 8.9e-15 54.8 0.0 8.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dynactin PF12455.3 EME80523.1 - 0.011 14.6 0.3 0.041 12.8 0.2 1.7 1 1 1 2 2 2 0 Dynein associated protein Methyltransf_27 PF13708.1 EME80523.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EME80524.1 - 8.9e-13 47.5 0.7 9.8e-13 47.4 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 FliL PF03748.9 EME80525.1 - 0.08 12.9 0.8 0.14 12.1 0.6 1.4 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL GH-E PF14410.1 EME80525.1 - 0.12 12.5 1.1 0.21 11.7 0.8 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Jnk-SapK_ap_N PF09744.4 EME80525.1 - 0.8 9.6 8.5 0.98 9.4 5.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.17 EME80525.1 - 1 9.3 10.5 0.79 9.7 5.6 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SeqA PF03925.8 EME80525.1 - 2.6 7.7 7.3 4 7.0 5.1 1.5 1 1 0 1 1 1 0 SeqA protein UPF0182 PF03699.8 EME80526.1 - 0.017 13.0 0.6 0.042 11.7 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) T2SM PF04612.7 EME80527.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M FA_hydroxylase PF04116.8 EME80528.1 - 8.6e-12 45.4 12.6 8.6e-12 45.4 8.7 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF412 PF04217.8 EME80528.1 - 0.037 13.8 1.0 0.073 12.8 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF412 DUF1768 PF08719.6 EME80530.1 - 3.8e-31 107.9 0.1 4.1e-31 107.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PQ-loop PF04193.9 EME80531.1 - 1.3e-39 133.5 5.9 3.3e-20 71.4 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat MARVEL PF01284.18 EME80532.1 - 3e-17 62.7 7.3 3.9e-17 62.4 5.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Amastin PF07344.6 EME80532.1 - 0.013 15.1 1.1 1.1 8.8 0.1 2.3 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF360 PF04020.8 EME80532.1 - 0.018 15.4 0.6 0.018 15.4 0.4 1.8 2 0 0 2 2 2 0 Membrane protein of unknown function Claudin_2 PF13903.1 EME80532.1 - 0.054 13.1 7.6 1.4 8.6 0.1 2.6 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 EME80532.1 - 0.067 12.7 0.5 0.21 11.1 0.0 2.0 1 1 1 2 2 2 0 SUR7/PalI family SEC-C PF02810.10 EME80532.1 - 0.099 12.2 0.1 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 SEC-C motif ABC2_membrane_2 PF12679.2 EME80532.1 - 0.33 9.7 5.0 1.4 7.7 0.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein SpoIIIAH PF12685.2 EME80533.1 - 0.042 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Hamartin PF04388.7 EME80533.1 - 1.2 7.7 8.8 1.7 7.2 6.1 1.1 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.11 EME80536.1 - 4e-32 111.2 45.1 2.9e-30 105.1 15.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfotransfer_3 PF13469.1 EME80538.1 - 0.041 14.8 1.7 0.076 13.9 1.1 1.5 1 1 0 1 1 1 0 Sulfotransferase family MFS_1 PF07690.11 EME80539.1 - 9.1e-25 87.1 47.5 9.1e-25 87.1 32.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME80539.1 - 7e-12 44.6 7.6 7e-12 44.6 5.3 3.2 2 1 2 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 EME80539.1 - 2.3e-08 32.7 15.9 2.3e-08 32.7 11.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-rbx1 PF12678.2 EME80551.1 - 0.00064 19.7 0.9 0.0011 19.0 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EME80551.1 - 0.00093 18.9 3.3 0.0017 18.1 2.3 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME80551.1 - 0.0029 17.6 1.2 0.0057 16.6 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME80551.1 - 0.025 14.2 3.0 0.04 13.5 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1936 PF09151.5 EME80551.1 - 0.025 14.0 0.4 2.7 7.5 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1936) zf-C3HC4_3 PF13920.1 EME80551.1 - 0.093 12.4 0.6 0.093 12.4 0.4 1.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4493 PF14900.1 EME80552.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) Fib_alpha PF08702.5 EME80553.1 - 0.53 10.4 11.5 0.049 13.7 2.3 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 EME80553.1 - 1.4 8.9 5.9 7 6.7 0.9 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HsbA PF12296.3 EME80554.1 - 4.9e-24 84.5 6.1 7.9e-24 83.8 4.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Reo_sigmaC PF04582.7 EME80554.1 - 0.43 9.7 5.0 1.2 8.2 3.5 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EME80554.1 - 0.44 10.3 4.7 0.47 10.2 1.4 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PARP PF00644.15 EME80557.1 - 3.8e-06 26.4 0.0 0.00022 20.6 0.0 3.0 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain peroxidase PF00141.18 EME80558.1 - 1.1e-81 273.7 0.0 1.1e-41 142.8 0.0 2.4 2 1 0 2 2 2 2 Peroxidase Peroxidase_2 PF01328.12 EME80560.1 - 4e-13 48.7 0.0 8.4e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 Med3 PF11593.3 EME80561.1 - 0.4 9.8 10.3 0.6 9.2 7.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TMEM154 PF15102.1 EME80561.1 - 2.2 7.9 3.9 3.7 7.2 2.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family Mucin PF01456.12 EME80561.1 - 5 6.8 22.7 0.56 9.9 12.7 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Peroxidase_2 PF01328.12 EME80562.1 - 8.4e-13 47.6 0.1 1.6e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 DUF3430 PF11912.3 EME80563.1 - 0.039 13.7 1.3 0.053 13.3 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) Abhydrolase_4 PF08386.5 EME80565.1 - 6.5e-14 51.6 0.0 1.6e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EME80565.1 - 2.9e-11 43.3 0.0 1.2e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME80565.1 - 7.7e-10 39.0 0.3 1.3e-08 35.0 0.0 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME80565.1 - 0.00014 21.6 0.0 0.0018 18.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3410 PF11890.3 EME80565.1 - 0.015 14.9 0.0 0.061 12.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Peroxidase_2 PF01328.12 EME80568.1 - 1.7e-13 49.9 1.9 4.6e-13 48.5 1.3 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 Lactamase_B PF00753.22 EME80569.1 - 0.017 14.7 0.3 0.037 13.6 0.2 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Nop14 PF04147.7 EME80569.1 - 0.019 12.9 0.8 0.03 12.2 0.6 1.3 1 0 0 1 1 1 0 Nop14-like family Pinin_SDK_N PF04697.8 EME80569.1 - 0.53 10.3 5.7 0.28 11.1 0.6 2.2 2 0 0 2 2 2 0 pinin/SDK conserved region Ribosomal_60s PF00428.14 EME80569.1 - 5 7.6 12.8 47 4.4 0.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rod_C PF10493.4 EME80572.1 - 0.0085 14.4 0.2 0.011 14.0 0.1 1.2 1 0 0 1 1 1 1 Rough deal protein C-terminal region Abhydrolase_6 PF12697.2 EME80574.1 - 2.5e-23 83.1 0.0 3.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME80574.1 - 3.2e-08 33.4 0.0 2.4e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME80574.1 - 4.1e-06 26.6 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EME80574.1 - 0.0066 15.2 0.0 0.46 9.2 0.0 2.4 2 1 0 2 2 2 2 Chlorophyllase RRM_2 PF04059.7 EME80576.1 - 1.1e-16 60.5 0.1 1.5e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EME80576.1 - 0.0056 16.2 0.1 0.066 12.8 0.1 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME80576.1 - 0.023 14.6 0.0 0.8 9.7 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Asp PF00026.18 EME80578.1 - 8.8e-70 235.4 0.1 1.1e-69 235.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME80578.1 - 1.9e-08 34.4 0.0 1.3e-07 31.7 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME80578.1 - 2.6e-07 31.0 0.0 0.0091 16.4 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EME80578.1 - 0.00059 19.4 0.0 0.015 14.8 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 EME80578.1 - 0.12 12.3 0.1 3.8 7.4 0.1 2.9 3 0 0 3 3 3 0 Retroviral aspartyl protease F-box PF00646.28 EME80579.1 - 0.00017 21.1 0.1 0.0004 19.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME80579.1 - 0.0021 17.7 0.2 0.0055 16.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like DUF2890 PF11081.3 EME80580.1 - 1.6 8.7 5.9 2.4 8.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Abhydrolase_4 PF08386.5 EME80581.1 - 5.3e-11 42.3 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein RP-C_C PF11800.3 EME80581.1 - 0.021 14.5 0.3 0.021 14.5 0.2 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Abhydrolase_1 PF00561.15 EME80581.1 - 0.042 13.3 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold HET PF06985.6 EME80583.1 - 5.2e-27 94.7 0.3 6.7e-27 94.3 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM154 PF15102.1 EME80584.1 - 0.0028 17.3 5.9 0.018 14.7 4.1 2.2 1 1 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.3 EME80584.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.1 EME80584.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 EME80584.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EME80584.1 - 0.21 12.0 0.9 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Aconitase PF00330.15 EME80585.1 - 1.7e-58 198.2 0.0 1.3e-39 135.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME80585.1 - 1.9e-17 63.5 0.0 3.8e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SpoVAD PF07451.6 EME80585.1 - 0.018 13.5 0.1 0.033 12.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF295 PF03478.13 EME80585.1 - 0.12 11.7 0.9 1.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF295) HMGL-like PF00682.14 EME80586.1 - 2.3e-48 164.9 0.0 3.8e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like 2-Hacid_dh_C PF02826.14 EME80587.1 - 5.9e-40 136.3 0.0 2.8e-24 85.2 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME80587.1 - 0.046 13.5 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.19 EME80587.1 - 0.094 12.6 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME80587.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.17 EME80588.1 - 1.1e-29 103.3 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2618 PF10940.3 EME80588.1 - 0.14 11.9 0.6 0.33 10.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) Iso_dh PF00180.15 EME80589.1 - 3.6e-110 368.1 0.0 4.1e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.17 EME80590.1 - 1.3e-34 119.4 0.0 1.8e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 EME80591.1 - 1.5e-65 221.3 24.8 3.5e-33 115.2 5.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME80591.1 - 3e-65 218.6 0.0 6.1e-34 117.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME80591.1 - 1.2e-14 54.1 3.0 5.9e-07 28.9 0.3 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME80591.1 - 4.8e-14 53.0 0.0 0.016 15.2 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_22 PF13401.1 EME80591.1 - 2.1e-09 37.5 0.3 0.0048 17.0 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME80591.1 - 5.7e-09 36.8 0.0 0.0071 17.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME80591.1 - 8.4e-09 35.6 1.4 0.00064 19.7 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EME80591.1 - 1.6e-07 30.7 0.1 0.0041 16.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EME80591.1 - 4.2e-07 29.2 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EME80591.1 - 5.9e-07 29.2 0.5 0.0022 17.5 0.0 2.7 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EME80591.1 - 8.9e-07 29.2 0.0 0.027 14.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EME80591.1 - 2.6e-06 27.2 3.2 0.0078 16.1 0.1 4.3 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME80591.1 - 6e-06 25.9 7.0 0.26 11.0 0.0 4.6 4 0 0 4 4 4 2 Part of AAA domain AAA_25 PF13481.1 EME80591.1 - 1.3e-05 24.6 1.8 0.26 10.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EME80591.1 - 2.5e-05 24.7 0.3 0.24 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EME80591.1 - 2.6e-05 23.8 3.1 0.29 10.6 0.0 4.3 3 1 1 4 4 4 1 AAA domain AAA_28 PF13521.1 EME80591.1 - 4.4e-05 23.5 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EME80591.1 - 6.4e-05 21.7 0.1 0.00096 17.8 0.1 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_14 PF13173.1 EME80591.1 - 6.8e-05 22.7 0.0 0.46 10.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.10 EME80591.1 - 0.00013 20.8 0.1 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EME80591.1 - 0.00013 21.5 1.5 1.8 7.9 0.0 4.3 4 0 0 4 4 4 1 AAA-like domain AAA_5 PF07728.9 EME80591.1 - 0.00066 19.4 0.0 1 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EME80591.1 - 0.00082 19.5 0.0 0.75 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 EME80591.1 - 0.0013 18.9 0.1 2.9 8.1 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EME80591.1 - 0.0024 17.0 0.1 0.15 11.1 0.0 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EME80591.1 - 0.0027 17.3 0.4 1.1 8.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.1 EME80591.1 - 0.006 16.4 0.0 4.7 7.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EME80591.1 - 0.0088 14.9 0.5 1 8.1 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain tRNA_lig_kinase PF08303.6 EME80591.1 - 0.01 15.7 0.0 0.4 10.5 0.0 3.0 2 1 0 2 2 2 0 tRNA ligase kinase domain PRK PF00485.13 EME80591.1 - 0.012 15.1 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 EME80591.1 - 0.013 15.3 0.0 0.99 9.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 EME80591.1 - 0.032 12.9 0.0 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.1 EME80591.1 - 0.035 13.6 0.6 3.7 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EME80591.1 - 0.05 13.2 0.1 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EME80591.1 - 0.057 12.8 0.0 4.2 6.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.1 EME80591.1 - 0.078 12.0 0.2 0.45 9.5 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.12 EME80591.1 - 0.084 12.2 1.3 19 4.6 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EME80591.1 - 0.1 12.1 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EME80591.1 - 0.11 12.1 0.0 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase MoaE PF02391.12 EME80591.1 - 0.13 12.1 2.6 6 6.7 0.2 3.3 3 0 0 3 3 3 0 MoaE protein MMR_HSR1 PF01926.18 EME80591.1 - 0.13 12.2 0.0 30 4.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EME80591.1 - 0.15 12.5 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AMP-binding PF00501.23 EME80592.1 - 0 1592.7 4.2 9.5e-85 284.4 0.0 7.1 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 EME80592.1 - 2.3e-245 811.4 0.0 6.7e-44 149.9 0.0 7.5 6 2 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EME80592.1 - 4.6e-67 222.2 7.1 5.1e-11 42.6 0.0 6.8 6 0 0 6 6 6 6 Phosphopantetheine attachment site Glyco_hydro_76 PF03663.9 EME80593.1 - 4.9e-146 486.8 30.4 6.5e-146 486.4 21.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Serum_albumin PF00273.15 EME80593.1 - 0.00059 19.3 0.1 0.0009 18.7 0.1 1.2 1 0 0 1 1 1 1 Serum albumin family F-box PF00646.28 EME80594.1 - 3e-06 26.7 0.0 8.5e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME80594.1 - 0.00089 18.9 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF829 PF05705.9 EME80596.1 - 4.2e-33 115.0 0.0 4.7e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TRI12 PF06609.8 EME80597.1 - 1.4e-25 89.5 26.4 1.7e-25 89.2 18.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME80597.1 - 4e-22 78.3 49.8 4e-22 78.3 34.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME80597.1 - 9.3e-10 37.6 9.6 9.3e-10 37.6 6.6 3.5 2 1 0 3 3 3 2 Sugar (and other) transporter MipA PF06629.7 EME80597.1 - 0.012 15.0 0.2 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 MltA-interacting protein MipA BTB PF00651.26 EME80598.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 BTB/POZ domain IFT43 PF15305.1 EME80599.1 - 0.92 9.5 5.1 0.28 11.2 0.2 2.2 2 1 0 2 2 2 0 Intraflagellar transport protein 43 Glyco_hydro_17 PF00332.13 EME80600.1 - 0.00029 19.9 0.2 0.00053 19.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 EME80600.1 - 0.0017 17.1 0.1 0.0026 16.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 MFS_1 PF07690.11 EME80601.1 - 1.1e-16 60.5 63.4 2.1e-14 53.0 41.7 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EME80604.1 - 5.2e-39 134.0 0.0 8.4e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Melibiase PF02065.13 EME80605.1 - 1.5e-138 461.7 0.0 1.9e-138 461.4 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 EME80605.1 - 4.5e-05 22.4 0.1 7.3e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 RNase_H PF00075.19 EME80606.1 - 8e-13 48.8 0.0 1e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 RNase H HTH_11 PF08279.7 EME80606.1 - 0.18 11.4 0.3 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 HTH domain F-box PF00646.28 EME80608.1 - 0.0028 17.2 0.1 0.0063 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME80608.1 - 0.062 13.0 0.1 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like SRR1 PF07985.7 EME80611.1 - 0.14 12.0 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 SRR1 CFEM PF05730.6 EME80614.1 - 0.00055 19.6 6.7 0.00055 19.6 4.6 1.9 2 0 0 2 2 2 1 CFEM domain HET PF06985.6 EME80615.1 - 3.8e-21 75.7 0.0 6.1e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pheromone PF08015.6 EME80616.1 - 3.7 8.4 10.7 1.2 10.0 2.5 3.6 3 1 0 3 3 3 0 Fungal mating-type pheromone 2-Hacid_dh_C PF02826.14 EME80621.1 - 4.8e-44 149.6 0.0 7.3e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME80621.1 - 9.9e-06 25.0 0.0 3.9e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EME80621.1 - 0.0022 17.8 0.0 0.0068 16.2 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 EME80621.1 - 0.0084 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase XdhC_C PF13478.1 EME80621.1 - 0.014 15.7 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 EME80621.1 - 0.023 14.9 0.0 0.08 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Transposase_23 PF03017.9 EME80621.1 - 0.055 12.9 0.1 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 TNP1/EN/SPM transposase IBR PF01485.16 EME80622.1 - 6.8e-07 29.0 2.9 6.8e-07 29.0 2.0 3.5 2 1 0 2 2 2 1 IBR domain DUF1515 PF07439.6 EME80623.1 - 0.62 9.8 4.2 4.5 7.1 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) DUF4565 PF15127.1 EME80629.1 - 0.062 13.6 0.3 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4565) MORN_2 PF07661.8 EME80631.1 - 0.046 13.7 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 MORN repeat variant SLX9 PF15341.1 EME80633.1 - 6.4e-26 91.1 3.0 1.1e-25 90.3 2.1 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 F-box PF00646.28 EME80635.1 - 0.0078 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain CAP_N PF01213.14 EME80635.1 - 0.61 9.3 4.2 0.95 8.6 2.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ADH_N PF08240.7 EME80642.1 - 3.5e-29 100.7 0.6 6.8e-29 99.8 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME80642.1 - 8.3e-18 64.1 0.0 1.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME80642.1 - 1e-05 26.3 0.0 2.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME80642.1 - 0.0002 20.9 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lar_restr_allev PF14354.1 EME80642.1 - 0.75 10.1 4.9 18 5.6 1.5 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar HET PF06985.6 EME80643.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF3708 PF12501.3 EME80645.1 - 0.026 14.3 2.2 0.033 14.0 1.1 1.5 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Abhydrolase_6 PF12697.2 EME80646.1 - 1.5e-18 67.5 0.0 1.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME80646.1 - 2.1e-08 34.0 0.0 4e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME80646.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family F-box PF00646.28 EME80649.1 - 0.00032 20.2 0.1 0.00061 19.3 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME80649.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like RNase_H PF00075.19 EME80652.1 - 1.1e-10 41.9 0.0 2.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNase H Mito_fiss_reg PF05308.6 EME80652.1 - 0.13 11.5 2.0 0.35 10.2 1.4 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Fungal_trans PF04082.13 EME80657.1 - 1.7e-17 63.2 0.0 2.4e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EBA-175_VI PF11556.3 EME80658.1 - 0.015 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 BTB PF00651.26 EME80659.1 - 2.4e-08 33.9 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_10 PF00331.15 EME80661.1 - 2.6e-83 279.7 0.0 2.9e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MFS_1 PF07690.11 EME80662.1 - 5.7e-36 123.9 25.2 8.8e-36 123.3 16.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PNK3P PF08645.6 EME80664.1 - 0.15 11.4 0.1 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase p450 PF00067.17 EME80665.1 - 0.096 11.1 0.1 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Glyco_tranf_2_3 PF13641.1 EME80671.1 - 3.5e-20 72.7 0.0 1.6e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EME80671.1 - 8.3e-15 54.8 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EME80671.1 - 0.00011 21.5 0.0 0.00057 19.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Peroxidase_2 PF01328.12 EME80673.1 - 1.3e-17 63.4 0.1 5.6e-17 61.3 0.0 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 ECH PF00378.15 EME80680.1 - 2e-38 131.8 0.1 2.1e-37 128.5 0.1 2.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Zn_clus PF00172.13 EME80683.1 - 1.4e-05 24.8 10.0 2e-05 24.4 7.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EME80683.1 - 0.0017 17.8 3.4 0.0054 16.2 2.3 1.9 1 0 0 1 1 1 1 AT hook motif TFIIE-A_C-term PF11521.3 EME80683.1 - 0.51 10.3 12.4 0.61 10.0 4.7 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Nop14 PF04147.7 EME80683.1 - 0.62 7.9 6.5 0.041 11.8 0.3 1.8 2 0 0 2 2 2 0 Nop14-like family MRI PF15325.1 EME80683.1 - 9.3 7.2 8.8 5.4 8.0 1.3 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection zf-C3HC4 PF00097.20 EME80688.1 - 0.15 11.7 15.5 0.018 14.7 7.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 EME80692.1 - 6.7e-08 32.3 6.0 1.5e-07 31.1 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EME80693.1 - 1.9e-73 247.0 0.0 4.4e-73 245.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EME80693.1 - 1.2e-33 116.8 0.0 1.8e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EME80693.1 - 1.7e-30 105.2 0.0 3.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EME80693.1 - 6.9e-25 88.6 0.0 3.5e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.1 EME80693.1 - 6.6e-24 84.5 0.0 1.6e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EME80693.1 - 7.9e-18 64.4 2.6 2.3e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EME80693.1 - 5.4e-08 33.0 2.5 0.00014 21.8 0.1 3.6 4 0 0 4 4 4 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EME80693.1 - 2.1e-06 26.9 0.2 4.7e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EME80693.1 - 5.3e-05 22.9 0.0 0.0082 15.9 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family ACP_syn_III PF08545.5 EME80693.1 - 0.045 13.4 0.6 0.42 10.3 0.2 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_3 PF01494.14 EME80694.1 - 4.7e-23 81.8 2.5 6.8e-14 51.6 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EME80694.1 - 0.0037 17.6 0.0 0.041 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME80694.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EME80694.1 - 0.0092 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ACP_syn_III PF08545.5 EME80694.1 - 0.037 13.6 0.3 0.49 10.1 0.0 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DAO PF01266.19 EME80694.1 - 0.037 12.9 0.1 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME80694.1 - 0.12 11.2 0.1 0.29 10.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_2 PF00891.13 EME80695.1 - 4.8e-29 101.2 0.0 6.5e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EME80695.1 - 9.5e-08 31.7 0.0 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80695.1 - 1.5e-06 28.7 0.1 6.5e-06 26.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME80695.1 - 5.3e-06 26.7 0.0 0.00012 22.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME80695.1 - 4.8e-05 23.7 0.1 0.0084 16.5 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EME80695.1 - 0.0019 17.5 0.0 0.0082 15.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.7 EME80695.1 - 0.0035 16.9 0.0 0.015 14.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EME80695.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EME80695.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FAD_binding_3 PF01494.14 EME80696.1 - 8.9e-22 77.6 0.4 2.7e-21 76.0 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME80696.1 - 9.6e-13 47.7 5.4 3.6e-09 36.0 2.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME80696.1 - 3.2e-09 36.1 0.3 5.2e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME80696.1 - 1.2e-08 34.8 0.7 3.1e-08 33.5 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME80696.1 - 4.2e-07 30.0 0.5 7.7e-07 29.1 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME80696.1 - 8.2e-07 27.8 1.2 2e-06 26.5 0.8 1.7 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EME80696.1 - 2.6e-06 26.8 0.3 0.00021 20.4 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EME80696.1 - 1.5e-05 24.0 0.1 1.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EME80696.1 - 2e-05 23.8 0.2 2.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME80696.1 - 3.1e-05 23.1 1.3 4.8e-05 22.5 0.9 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EME80696.1 - 0.00022 21.5 0.8 0.00082 19.7 0.7 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME80696.1 - 0.00026 20.0 1.8 0.0055 15.6 0.7 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EME80696.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EME80696.1 - 0.0016 18.1 0.2 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EME80696.1 - 0.0028 16.3 0.6 0.0082 14.8 0.3 1.8 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_7 PF13241.1 EME80696.1 - 0.0047 17.1 0.0 0.017 15.3 0.0 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EME80696.1 - 0.0057 16.2 1.1 0.012 15.1 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EME80696.1 - 0.012 15.0 0.6 0.022 14.2 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EME80696.1 - 0.04 13.3 0.9 0.066 12.5 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SE PF08491.5 EME80696.1 - 0.12 11.1 0.0 0.32 9.7 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 EME80696.1 - 0.12 12.1 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding ABC2_membrane PF01061.19 EME80697.1 - 1.4e-60 204.0 47.8 1.2e-33 116.0 8.1 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EME80697.1 - 7.3e-32 110.5 0.1 8.6e-17 61.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EME80697.1 - 2.4e-12 46.3 7.1 2.6e-11 43.1 0.0 3.3 3 0 0 3 3 2 1 CDR ABC transporter AAA_16 PF13191.1 EME80697.1 - 1e-07 32.1 2.9 0.0013 18.7 0.6 2.7 2 1 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.2 EME80697.1 - 2.2e-06 26.9 5.6 2.2e-06 26.9 3.9 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EME80697.1 - 4.1e-06 26.0 0.3 0.005 16.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 EME80697.1 - 1.2e-05 25.4 0.1 0.0026 17.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME80697.1 - 1.5e-05 24.4 1.3 0.053 13.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EME80697.1 - 2.3e-05 23.9 0.1 0.0025 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME80697.1 - 3e-05 24.1 0.1 0.083 13.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EME80697.1 - 0.00033 20.2 0.7 0.093 12.2 0.4 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EME80697.1 - 0.00094 18.8 0.3 0.35 10.5 0.1 2.6 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 EME80697.1 - 0.0015 18.4 0.0 0.071 13.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 EME80697.1 - 0.0045 16.2 1.5 1.4 8.1 0.0 3.8 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EME80697.1 - 0.0055 17.1 0.0 0.32 11.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EME80697.1 - 0.0067 15.3 0.2 1.3 7.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EME80697.1 - 0.012 15.0 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EME80697.1 - 0.021 14.7 0.3 0.12 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME80697.1 - 0.023 14.4 0.7 1.8 8.3 0.2 3.0 3 0 0 3 3 2 0 Part of AAA domain IstB_IS21 PF01695.12 EME80697.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EME80697.1 - 0.039 13.4 0.7 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRPRB PF09439.5 EME80697.1 - 0.043 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EME80697.1 - 0.049 13.0 0.7 0.73 9.2 0.2 2.2 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 EME80697.1 - 0.068 12.6 0.3 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EME80697.1 - 0.074 12.0 0.0 10 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EME80697.1 - 0.096 12.8 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EME80697.1 - 0.15 11.8 0.9 1.8 8.3 0.2 2.4 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EME80697.1 - 0.15 11.7 0.0 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 EME80697.1 - 0.18 11.7 0.4 0.58 10.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EME80697.1 - 0.19 12.0 0.3 0.79 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EME80697.1 - 0.21 10.6 0.2 0.47 9.5 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 EME80697.1 - 0.23 10.9 0.5 13 5.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EME80697.1 - 0.31 10.6 0.0 1.1 8.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EME80697.1 - 0.31 10.4 0.4 1.1 8.7 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EME80697.1 - 0.34 11.7 1.2 1.5 9.6 0.2 2.6 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EME80697.1 - 0.53 9.1 1.5 19 3.9 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain Aa_trans PF01490.13 EME80698.1 - 1.9e-80 270.3 33.3 2.2e-80 270.1 23.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1240 PF06836.7 EME80698.1 - 7 6.9 17.0 3.7 7.8 0.5 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) ABC_membrane PF00664.18 EME80699.1 - 3.1e-50 171.1 41.7 9.7e-34 117.0 15.2 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EME80699.1 - 1.7e-48 164.3 0.0 4.8e-28 98.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME80699.1 - 1.6e-07 31.6 0.9 0.042 13.8 0.0 4.3 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EME80699.1 - 2.3e-06 26.8 0.3 0.00058 19.0 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin MMR_HSR1 PF01926.18 EME80699.1 - 3.1e-06 27.1 0.0 0.17 11.8 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EME80699.1 - 8.7e-06 25.1 1.1 0.12 11.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EME80699.1 - 3.2e-05 23.2 0.2 0.98 8.5 0.1 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME80699.1 - 3.3e-05 23.9 0.3 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EME80699.1 - 6.8e-05 23.3 0.8 0.058 13.9 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EME80699.1 - 0.00013 22.7 3.2 0.37 11.6 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME80699.1 - 0.00065 19.1 0.1 0.42 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EME80699.1 - 0.00096 18.7 0.8 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EME80699.1 - 0.0013 17.9 1.8 0.32 10.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 EME80699.1 - 0.003 16.3 3.0 0.54 8.9 0.4 2.6 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EME80699.1 - 0.0058 16.1 0.6 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EME80699.1 - 0.0072 16.4 0.5 4.3 7.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 EME80699.1 - 0.014 15.2 0.6 0.014 15.2 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function DUF87 T2SE PF00437.15 EME80699.1 - 0.021 13.7 0.0 4.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 EME80699.1 - 0.025 14.2 1.0 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EME80699.1 - 0.08 12.4 0.7 5.9 6.2 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EME80699.1 - 0.1 12.0 0.2 5.7 6.3 0.0 2.9 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain NACHT PF05729.7 EME80699.1 - 0.12 12.0 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EME80699.1 - 0.18 12.0 0.2 40 4.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 EME80699.1 - 0.3 10.5 2.2 10 5.5 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EME80699.1 - 0.71 10.1 6.0 13 6.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 EME80699.1 - 1.2 9.3 16.2 2.3 8.4 0.0 4.2 3 1 1 4 4 3 0 AAA domain Dynamin_N PF00350.18 EME80699.1 - 8.2 6.2 16.0 0.054 13.3 0.4 3.3 4 0 0 4 4 3 0 Dynamin family Glyco_hydro_62 PF03664.8 EME80700.1 - 1.6e-101 339.0 7.5 2.8e-67 226.6 0.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 62 Glyco_hydro_61 PF03443.9 EME80701.1 - 2.5e-34 119.0 0.0 3.2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldedh PF00171.17 EME80705.1 - 1.1e-16 60.2 0.0 1.2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Prenyltrans_2 PF13249.1 EME80706.1 - 4.9e-09 36.5 0.3 3e-05 24.3 0.0 3.0 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME80706.1 - 0.00012 22.0 0.0 0.0016 18.4 0.0 2.7 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans PF00432.16 EME80706.1 - 0.078 12.5 0.0 0.61 9.6 0.0 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Claudin_2 PF13903.1 EME80707.1 - 0.0088 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2892 PF11127.3 EME80707.1 - 0.08 12.7 2.8 0.15 11.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Surface_Ag_2 PF01617.12 EME80707.1 - 0.3 10.2 3.6 0.51 9.5 2.5 1.3 1 0 0 1 1 1 0 Surface antigen MFS_1 PF07690.11 EME80708.1 - 2.6e-35 121.7 29.7 4.1e-35 121.1 20.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PgaD PF13994.1 EME80708.1 - 0.55 9.7 4.2 2.4 7.6 0.0 3.3 4 0 0 4 4 4 0 PgaD-like protein CoA_binding_3 PF13727.1 EME80708.1 - 7.4 6.3 10.1 0.48 10.2 0.5 3.0 2 2 1 3 3 3 0 CoA-binding domain Amino_oxidase PF01593.19 EME80709.1 - 6.9e-56 190.2 0.0 8.5e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 EME80709.1 - 1.3e-16 60.4 0.0 2.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 EME80709.1 - 4.2e-14 52.3 0.8 8.1e-14 51.4 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME80709.1 - 1e-10 41.0 0.1 1.4e-07 30.7 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME80709.1 - 1.7e-08 33.7 0.9 2.6e-08 33.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME80709.1 - 3.4e-07 29.6 0.1 6.3e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EME80709.1 - 3.7e-07 29.4 0.3 0.00012 21.1 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 EME80709.1 - 9e-07 28.3 0.6 1.4e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME80709.1 - 9.3e-07 29.1 0.0 1.3e-05 25.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME80709.1 - 1.3e-05 25.1 0.1 5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME80709.1 - 9e-05 21.6 0.7 0.00015 20.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EME80709.1 - 0.00014 20.8 0.3 0.00031 19.7 0.2 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EME80709.1 - 0.00053 19.8 1.1 0.13 12.0 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EME80709.1 - 0.00084 17.9 2.4 0.0009 17.8 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EME80709.1 - 0.014 15.8 0.1 0.041 14.2 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EME80709.1 - 0.033 13.7 0.1 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4596 PF15363.1 EME80711.1 - 0.088 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Adeno_E3_14_5 PF04834.7 EME80711.1 - 0.32 11.4 0.2 0.32 11.4 0.1 2.6 3 0 0 3 3 3 0 Early E3 14.5 kDa protein OTT_1508_deam PF14441.1 EME80712.1 - 6.8e-09 35.6 0.1 1.6e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF4375 PF14300.1 EME80712.1 - 0.079 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) zf-UBR PF02207.15 EME80713.1 - 1.3e-16 60.0 4.9 1.3e-16 60.0 3.4 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Acetyltransf_1 PF00583.19 EME80714.1 - 1.3e-16 60.3 0.0 1.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME80714.1 - 3.1e-10 40.0 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME80714.1 - 3.7e-10 39.9 0.0 4.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME80714.1 - 2.9e-09 37.2 0.0 3.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME80714.1 - 1.7e-08 34.1 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EME80714.1 - 2.5e-07 30.7 0.0 3.4e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME80714.1 - 0.00011 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME80714.1 - 0.00011 22.0 0.3 0.00018 21.3 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME80714.1 - 0.0018 18.1 0.1 0.003 17.3 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 EME80714.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase LCAT PF02450.10 EME80715.1 - 2.2e-100 336.3 0.2 6.1e-100 334.9 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EME80715.1 - 0.025 14.3 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 EME80715.1 - 0.035 13.4 0.1 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.5 EME80715.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF900 PF05990.7 EME80715.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Na_Ca_ex PF01699.19 EME80716.1 - 2.2e-08 33.8 24.7 1.1e-07 31.5 2.8 3.2 3 1 0 3 3 3 2 Sodium/calcium exchanger protein MscS_TM PF12794.2 EME80716.1 - 0.73 8.3 15.0 0.0074 14.9 5.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Grp1_Fun34_YaaH PF01184.14 EME80718.1 - 3.8e-25 88.4 13.8 5.1e-25 88.0 9.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.11 EME80719.1 - 4.5e-36 124.2 30.2 4.5e-36 124.2 20.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cyt-b5 PF00173.23 EME80720.1 - 5.4e-15 54.9 0.1 5.9e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRX PF08381.6 EME80720.1 - 0.27 10.3 1.5 3.4 6.7 1.1 2.6 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Gly_transf_sug PF04488.10 EME80721.1 - 4.7e-08 33.3 0.0 7.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif oligo_HPY PF08352.7 EME80721.1 - 0.063 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region TcdA_TcdB PF12919.2 EME80721.1 - 0.12 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EME80721.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein zf-A20 PF01754.11 EME80721.1 - 0.46 10.0 2.0 0.79 9.3 1.4 1.3 1 0 0 1 1 1 0 A20-like zinc finger PA26 PF04636.8 EME80722.1 - 0.44 9.1 1.9 0.55 8.8 1.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Coatomer_WDAD PF04053.9 EME80723.1 - 7.2e-151 502.9 0.0 1.4e-150 501.9 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EME80723.1 - 3e-77 259.9 0.1 4.2e-77 259.4 0.1 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EME80723.1 - 3.5e-48 159.8 12.6 1.2e-08 34.5 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EME80723.1 - 0.0035 15.5 5.8 0.39 8.8 0.0 3.5 1 1 2 4 4 4 2 Nucleoporin Nup120/160 CRISPR_Cas2 PF09827.4 EME80723.1 - 0.019 15.1 0.2 7.3 6.8 0.0 2.9 2 0 0 2 2 2 0 CRISPR associated protein Cas2 Clathrin PF00637.15 EME80723.1 - 0.1 12.2 0.1 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS Mad3_BUB1_I PF08311.7 EME80724.1 - 2.2e-44 150.2 0.2 2.2e-44 150.2 0.1 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EME80724.1 - 1.9e-14 53.4 0.1 5.4e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80724.1 - 0.0011 18.0 0.0 0.0037 16.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME80724.1 - 0.27 10.9 5.7 0.29 10.8 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cir_N PF10197.4 EME80726.1 - 0.0063 16.5 4.2 0.0063 16.5 2.9 4.6 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR OB_NTP_bind PF07717.11 EME80728.1 - 2.5e-28 98.1 0.0 8.9e-28 96.4 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME80728.1 - 1.9e-24 85.5 0.1 1.9e-24 85.5 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME80728.1 - 6.8e-12 45.0 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME80728.1 - 9.6e-05 22.5 0.0 0.00033 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EME80728.1 - 0.00013 21.4 0.0 0.00043 19.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EME80728.1 - 0.0015 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EME80728.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME80728.1 - 0.4 10.9 0.0 0.4 10.9 0.0 3.1 3 1 0 3 3 3 0 ABC transporter CALCOCO1 PF07888.6 EME80729.1 - 0.25 9.5 26.9 0.0053 15.0 13.7 1.7 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Borrelia_P83 PF05262.6 EME80729.1 - 0.44 8.7 21.7 0.64 8.2 15.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CPSase_L_D2 PF02786.12 EME80730.1 - 7.8e-50 169.0 0.1 1.6e-49 168.0 0.1 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EME80730.1 - 6.9e-32 109.6 0.0 2.5e-31 107.8 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EME80730.1 - 7.5e-28 96.8 0.1 1.7e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EME80730.1 - 1.5e-13 50.8 0.1 8e-13 48.5 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EME80730.1 - 2.1e-11 43.3 2.6 4.6e-11 42.1 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EME80730.1 - 8.4e-11 41.1 0.0 6.8e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EME80730.1 - 4.1e-07 29.5 0.0 7.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EME80730.1 - 0.00016 21.0 0.0 0.00065 19.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain DUF2118 PF09891.4 EME80730.1 - 0.0064 16.2 0.4 0.017 14.8 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RimK PF08443.6 EME80730.1 - 0.0079 15.6 0.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain PHB_acc_N PF07879.6 EME80730.1 - 0.017 14.8 0.1 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain Biotin_lipoyl_2 PF13533.1 EME80730.1 - 0.057 13.0 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like RRM_1 PF00076.17 EME80732.1 - 5.7e-15 54.6 0.1 9.1e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME80732.1 - 6.3e-10 38.8 0.0 1e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME80732.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XS PF03468.9 EME80732.1 - 0.069 13.0 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 XS domain MbeD_MobD PF04899.7 EME80732.1 - 0.072 12.9 0.5 0.16 11.8 0.4 1.6 1 0 0 1 1 1 0 MbeD/MobD like APH PF01636.18 EME80733.1 - 7.1e-12 45.5 0.0 2.1e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME80733.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DnaJ PF00226.26 EME80735.1 - 4.9e-25 87.0 5.3 8.6e-25 86.2 3.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EME80735.1 - 1.6e-13 50.5 18.8 2.9e-13 49.6 13.0 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EME80735.1 - 5e-11 42.3 0.0 2.9e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EME80735.1 - 0.00042 19.9 7.5 0.045 13.4 0.3 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF1311 PF07007.7 EME80735.1 - 0.038 14.0 0.4 0.085 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Lar_restr_allev PF14354.1 EME80735.1 - 0.38 11.0 4.4 3.2 8.1 3.0 2.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 EME80735.1 - 3.5 7.5 14.6 43 4.0 10.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn_clus PF00172.13 EME80736.1 - 0.014 15.2 13.9 0.024 14.5 9.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MIT PF04212.13 EME80737.1 - 3e-11 43.0 0.5 7e-11 41.8 0.4 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain p450 PF00067.17 EME80739.1 - 3.1e-46 157.8 0.0 7.3e-46 156.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Bac_rhodopsin PF01036.13 EME80740.1 - 2e-50 171.1 7.5 2.8e-50 170.6 5.2 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MFS_1 PF07690.11 EME80741.1 - 1.7e-08 33.6 31.5 2.5e-08 33.0 21.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EME80741.1 - 9.5e-06 25.1 3.7 9.5e-06 25.1 2.6 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Bac_luciferase PF00296.15 EME80742.1 - 2.9e-50 171.1 0.0 4e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 EME80743.1 - 6.9e-06 25.6 0.1 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME80743.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME80743.1 - 0.013 16.3 0.0 0.04 14.8 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EME80744.1 - 6.6e-24 85.0 0.0 1.7e-23 83.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME80744.1 - 2.3e-19 68.9 0.0 7.6e-19 67.2 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME80744.1 - 1.8e-10 40.6 0.1 9.4e-10 38.3 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME80744.1 - 4.7e-07 29.0 0.0 4.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME80744.1 - 4.4e-05 23.2 0.1 0.0036 17.0 0.0 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME80744.1 - 6.7e-05 22.8 0.0 0.0002 21.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME80744.1 - 0.0048 17.2 0.4 2.3 8.6 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME80744.1 - 0.018 13.9 0.0 0.081 11.8 0.0 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EME80744.1 - 0.11 11.5 0.1 0.25 10.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NuA4 PF09340.5 EME80744.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 GIDA PF01134.17 EME80744.1 - 0.23 10.2 0.6 0.42 9.4 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF2183 PF09949.4 EME80745.1 - 1.4e-17 63.4 0.2 3e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CotJA PF11007.3 EME80745.1 - 0.0056 16.2 0.4 0.35 10.5 0.1 2.6 1 1 1 2 2 2 1 Spore coat associated protein JA (CotJA) DUF1583 PF07622.6 EME80745.1 - 0.023 13.1 0.0 0.033 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) Peptidase_C2 PF00648.16 EME80746.1 - 2.7e-18 66.0 0.6 1.3e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease KAR9 PF08580.5 EME80749.1 - 7.5e-105 351.7 13.1 9e-105 351.4 9.1 1.0 1 0 0 1 1 1 1 Yeast cortical protein KAR9 FemAB PF02388.11 EME80749.1 - 0.14 10.8 0.1 0.27 9.8 0.1 1.4 1 0 0 1 1 1 0 FemAB family CK2S PF15011.1 EME80749.1 - 0.18 11.6 5.3 6.2 6.5 0.0 3.5 3 1 0 3 3 3 0 Casein Kinase 2 substrate Striatin PF08232.7 EME80749.1 - 0.24 11.7 0.1 0.24 11.7 0.0 2.9 2 0 0 2 2 2 0 Striatin family Syntaxin-6_N PF09177.6 EME80749.1 - 0.35 11.2 12.8 3.1 8.2 0.2 4.3 2 2 1 4 4 4 0 Syntaxin 6, N-terminal CH PF00307.26 EME80750.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain HTH_38 PF13936.1 EME80751.1 - 3.5e-08 32.8 4.0 0.18 11.3 0.3 4.6 4 0 0 4 4 4 3 Helix-turn-helix domain HTH_23 PF13384.1 EME80751.1 - 1.4e-06 27.7 4.8 2.7e-05 23.6 0.3 3.9 3 0 0 3 3 3 1 Homeodomain-like domain GcrA PF07750.6 EME80751.1 - 1.7e-05 25.1 2.6 0.0068 16.6 0.8 2.8 2 0 0 2 2 2 2 GcrA cell cycle regulator HTH_28 PF13518.1 EME80751.1 - 2.6e-05 24.1 0.7 0.00094 19.1 0.2 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EME80751.1 - 0.001 18.4 0.1 0.0039 16.6 0.1 2.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.1 EME80751.1 - 0.0013 18.8 0.4 0.0072 16.4 0.2 2.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_20 PF12840.2 EME80751.1 - 0.0038 17.0 0.1 0.64 9.8 0.0 3.3 2 1 1 3 3 3 1 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.1 EME80751.1 - 0.0046 17.0 0.0 0.53 10.4 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain TrmB PF01978.14 EME80751.1 - 0.0067 16.0 0.1 4.1 7.1 0.0 3.0 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.4 EME80751.1 - 0.0094 15.8 0.0 2.9 7.8 0.0 2.9 3 0 0 3 3 2 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_Tnp_1 PF01527.15 EME80751.1 - 0.016 15.1 1.0 0.37 10.7 0.7 2.4 1 1 0 1 1 1 0 Transposase HTH_7 PF02796.10 EME80751.1 - 0.023 14.5 0.9 0.023 14.5 0.6 3.6 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.2 EME80751.1 - 0.051 13.8 0.1 0.72 10.1 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.14 EME80751.1 - 0.067 12.5 0.0 0.27 10.5 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family MerR_1 PF13411.1 EME80751.1 - 0.073 12.8 0.9 2.6 7.9 0.2 3.2 3 0 0 3 3 3 0 MerR HTH family regulatory protein HTH_Tnp_IS630 PF01710.11 EME80751.1 - 0.18 11.4 3.3 0.32 10.6 0.0 2.5 2 0 0 2 2 2 0 Transposase Epimerase PF01370.16 EME80752.1 - 6.6e-06 25.7 0.0 9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME80752.1 - 0.00022 21.2 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EME80752.1 - 0.0034 17.2 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME80752.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Transp_cyt_pur PF02133.10 EME80753.1 - 2.1e-92 309.9 39.5 2.4e-92 309.7 27.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin WD40 PF00400.27 EME80754.1 - 6.2e-61 200.2 18.9 1.1e-13 50.4 0.2 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EME80754.1 - 1.8e-11 42.8 2.0 0.0057 14.8 0.1 4.2 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EME80754.1 - 2.9e-09 36.9 0.0 0.0005 19.8 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EME80754.1 - 5.6e-07 28.6 0.3 0.57 8.8 0.0 3.7 1 1 3 4 4 4 3 Nup133 N terminal like DUF1513 PF07433.6 EME80754.1 - 6.6e-07 28.5 0.2 0.16 10.8 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF1513) PD40 PF07676.7 EME80754.1 - 6.8e-05 22.4 1.7 0.87 9.3 0.1 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EME80754.1 - 0.00034 18.9 0.0 0.011 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Gmad1 PF10647.4 EME80754.1 - 0.0024 17.2 0.2 0.025 13.9 0.1 2.4 1 1 2 3 3 3 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EME80754.1 - 0.0064 15.9 0.4 0.073 12.5 0.3 2.4 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 EME80754.1 - 0.0066 14.7 0.0 0.12 10.6 0.0 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain VID27 PF08553.5 EME80754.1 - 0.0078 14.5 0.4 0.076 11.2 0.1 2.2 2 1 1 3 3 3 2 VID27 cytoplasmic protein Nbas_N PF15492.1 EME80754.1 - 0.0099 15.0 0.4 2.8 6.9 0.0 3.7 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 EME80754.1 - 0.047 12.4 0.0 1.9 7.1 0.0 2.6 1 1 0 2 2 2 0 Coatomer WD associated region IKI3 PF04762.7 EME80754.1 - 0.053 11.3 0.0 0.11 10.2 0.0 1.5 2 0 0 2 2 2 0 IKI3 family MMS1_N PF10433.4 EME80754.1 - 0.15 10.1 0.0 1 7.4 0.0 2.2 1 1 2 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term BNR_2 PF13088.1 EME80756.1 - 2.6e-06 26.9 0.2 0.016 14.4 0.0 2.2 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EME80756.1 - 0.049 13.4 7.2 0.054 13.3 0.5 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat ApbA PF02558.11 EME80757.1 - 3e-27 94.9 0.0 3e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EME80757.1 - 2.5e-22 79.1 0.0 5.2e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.1 EME80757.1 - 0.0038 17.4 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 EME80757.1 - 0.0042 16.0 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EME80757.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EME80757.1 - 0.021 15.2 0.1 0.049 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME80757.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EME80757.1 - 0.039 14.3 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EME80757.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ThiF PF00899.16 EME80757.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.8 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.14 EME80757.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Adaptin_N PF01602.15 EME80758.1 - 7.7e-147 489.7 4.9 9e-147 489.5 3.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EME80758.1 - 2.2e-26 92.7 1.3 4.4e-25 88.5 0.2 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EME80758.1 - 1.5e-17 63.6 1.7 1.5e-08 34.7 0.0 5.2 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EME80758.1 - 7.6e-12 44.2 4.3 0.0066 16.4 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.3 EME80758.1 - 0.0009 18.6 1.4 0.5 9.6 0.0 4.1 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.1 EME80758.1 - 0.001 19.4 11.3 0.66 10.5 0.0 7.1 8 1 1 9 9 9 1 HEAT-like repeat UNC45-central PF11701.3 EME80758.1 - 0.014 15.0 0.1 0.3 10.7 0.1 2.5 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Arm PF00514.18 EME80758.1 - 0.016 15.0 1.9 56 3.7 0.0 5.2 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EME80758.1 - 0.061 13.0 0.0 2.1 8.1 0.0 2.9 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain AF0941-like PF14591.1 EME80758.1 - 0.53 10.3 3.8 0.94 9.5 1.9 1.9 2 0 0 2 2 2 0 AF0941-like RasGEF_N_2 PF14663.1 EME80758.1 - 1.2 9.1 4.9 2.1 8.3 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glyco_transf_20 PF00982.16 EME80760.1 - 5.3e-199 661.5 0.0 6.1e-199 661.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EME80760.1 - 0.0014 18.0 0.4 0.16 11.3 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EME80760.1 - 0.008 15.7 0.3 0.017 14.5 0.1 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Cutinase PF01083.17 EME80762.1 - 3e-33 115.0 0.9 3.6e-33 114.8 0.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EME80762.1 - 0.00024 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.3 EME80762.1 - 0.002 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 EME80762.1 - 0.003 17.3 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME80762.1 - 0.013 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EME80763.1 - 2.1e-11 43.1 41.1 1.6e-07 30.4 6.1 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 EME80763.1 - 3.7e-05 22.0 4.2 9.3e-05 20.7 2.9 1.7 1 1 0 1 1 1 1 Transmembrane secretion effector DUF4231 PF14015.1 EME80763.1 - 0.14 12.1 1.2 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ADH_zinc_N PF00107.21 EME80764.1 - 6.5e-07 28.9 0.2 0.00038 20.0 0.0 2.2 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 EME80764.1 - 1.1e-05 25.1 0.0 6e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_2 PF07992.9 EME80764.1 - 0.021 14.6 0.1 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CSTF2_hinge PF14327.1 EME80765.1 - 7.6e-23 80.4 2.6 7.6e-23 80.4 1.8 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EME80765.1 - 4.7e-21 74.1 0.0 7.9e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME80765.1 - 5.9e-18 64.6 0.0 1.3e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME80765.1 - 6.1e-10 38.7 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EME80765.1 - 2.5e-05 23.4 2.7 7.1e-05 22.0 1.9 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal PAT1 PF09770.4 EME80765.1 - 9.1 4.3 14.8 13 3.8 10.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AA_permease PF00324.16 EME80766.1 - 2.7e-85 286.5 43.3 3.4e-85 286.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME80766.1 - 3e-21 75.4 44.4 4.1e-21 75.0 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease zf-C2H2_4 PF13894.1 EME80767.1 - 3.1e-08 33.3 20.2 0.005 17.0 0.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EME80767.1 - 0.00098 19.3 22.0 0.045 14.0 0.1 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type Patatin PF01734.17 EME80769.1 - 0.0088 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4055 PF13264.1 EME80769.1 - 0.097 12.7 0.4 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) EspF PF04806.7 EME80769.1 - 2.9 8.1 9.9 1.5 9.0 0.7 2.5 2 0 0 2 2 2 0 EspF protein repeat Acyltransferase PF01553.16 EME80770.1 - 2.3e-26 91.8 0.0 3.2e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Baculo_PEP_C PF04513.7 EME80771.1 - 0.0026 17.6 16.5 0.27 11.0 6.1 3.3 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EME80771.1 - 0.01 15.5 2.4 0.01 15.5 1.7 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) HPPK PF01288.15 EME80771.1 - 0.021 14.5 0.2 0.021 14.5 0.2 2.7 3 1 0 3 3 3 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Filament PF00038.16 EME80771.1 - 0.13 11.6 34.1 0.28 10.6 11.4 2.5 1 1 1 2 2 2 0 Intermediate filament protein HsbA PF12296.3 EME80771.1 - 0.16 11.8 5.5 9.3 6.1 0.0 3.6 3 1 1 4 4 4 0 Hydrophobic surface binding protein A Lectin_N PF03954.9 EME80771.1 - 1 8.7 15.4 0.24 10.8 0.1 3.9 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain ApoLp-III PF07464.6 EME80771.1 - 8.7 6.3 21.7 1 9.3 3.6 3.2 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Pkinase PF00069.20 EME80773.1 - 2.3e-07 30.2 0.0 0.00014 21.1 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME80773.1 - 0.036 13.1 0.0 1.2 8.1 0.0 2.8 2 1 0 2 2 2 0 Protein tyrosine kinase MFS_1 PF07690.11 EME80774.1 - 1.8e-26 92.7 27.3 1.8e-26 92.7 18.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MNSV_P7B PF06692.6 EME80774.1 - 0.15 11.8 0.8 0.32 10.8 0.6 1.5 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Fasciclin PF02469.17 EME80775.1 - 2.5e-34 118.0 2.2 9.7e-21 74.1 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.20 EME80776.1 - 1.7e-42 145.4 0.0 2.7e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80776.1 - 7.7e-27 93.9 0.0 1.2e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3292 PF11696.3 EME80776.1 - 1.5 6.5 6.0 0.85 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Metallopep PF12044.3 EME80780.1 - 8.6e-122 406.6 0.0 1.2e-121 406.0 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.1 EME80780.1 - 0.0011 19.0 0.6 0.0021 18.1 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EME80780.1 - 0.0014 19.1 0.6 0.0032 17.9 0.4 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EME80780.1 - 0.0035 16.8 0.4 0.0066 15.9 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EME80780.1 - 0.0046 16.9 0.7 0.0093 15.9 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Mito_carr PF00153.22 EME80781.1 - 2e-63 210.1 7.9 1.3e-21 76.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Apolipoprotein PF01442.13 EME80781.1 - 0.0047 16.4 0.6 0.0082 15.6 0.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain IncA PF04156.9 EME80781.1 - 0.16 11.5 1.7 0.27 10.8 1.2 1.3 1 0 0 1 1 1 0 IncA protein p450 PF00067.17 EME80782.1 - 4.6e-57 193.5 0.0 6.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMS PF00817.15 EME80783.1 - 6.9e-39 133.0 0.0 1.5e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family DUF4414 PF14377.1 EME80783.1 - 5.4e-17 61.6 12.0 3.6e-06 26.8 0.0 5.8 4 1 0 4 4 4 2 Domain of unknown function (DUF4414) IMS_C PF11799.3 EME80783.1 - 7e-15 55.0 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EME80783.1 - 4.8e-06 26.6 0.0 1.6e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EME80783.1 - 1.5e-05 24.7 1.2 0.00017 21.4 0.0 3.2 3 0 0 3 3 3 1 IMS family HHH motif PTCB-BRCT PF12738.2 EME80783.1 - 7.4e-05 22.5 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 EME80783.1 - 0.0042 17.2 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain MgtE_N PF03448.12 EME80783.1 - 0.043 14.1 2.3 11 6.4 0.1 3.8 4 0 0 4 4 4 0 MgtE intracellular N domain FliG_M PF14841.1 EME80783.1 - 0.12 12.3 1.1 28 4.7 0.0 3.7 3 0 0 3 3 3 0 FliG middle domain FKBP_C PF00254.23 EME80784.1 - 2.7e-32 110.6 0.0 6.6e-32 109.3 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box-like PF12937.2 EME80787.1 - 0.017 14.8 0.2 0.053 13.2 0.0 2.0 2 0 0 2 2 2 0 F-box-like Peroxidase_2 PF01328.12 EME80788.1 - 0.0017 17.1 4.2 0.011 14.3 0.1 2.8 3 0 0 3 3 3 2 Peroxidase, family 2 CFEM PF05730.6 EME80789.1 - 0.012 15.3 5.3 0.012 15.3 3.7 2.4 2 0 0 2 2 2 0 CFEM domain FAD_binding_4 PF01565.18 EME80790.1 - 1.3e-23 83.0 2.9 2.5e-23 82.0 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain PDGLE PF13190.1 EME80790.1 - 0.0051 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 PDGLE domain BBE PF08031.7 EME80790.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like AAA_32 PF13654.1 EME80790.1 - 0.096 11.3 0.1 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SKG6 PF08693.5 EME80790.1 - 0.17 11.2 3.9 0.44 9.9 2.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box-like PF12937.2 EME80792.1 - 0.0018 17.9 0.1 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Lipocalin_2 PF08212.7 EME80793.1 - 1.8e-10 40.7 0.0 4.1e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Lipocalin-like domain muHD PF10291.4 EME80794.1 - 2.1e-69 233.5 0.0 3.3e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EME80794.1 - 4.2e-09 36.4 0.0 1.4e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain HSP20 PF00011.16 EME80795.1 - 1.1e-20 73.4 0.8 3.3e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family pRN1_helical PF13010.1 EME80796.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Primase helical domain KxDL PF10241.4 EME80797.1 - 2.6e-29 100.9 2.1 3.5e-29 100.5 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4259 PF14078.1 EME80797.1 - 0.12 12.9 0.3 0.17 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Mating_C PF12737.2 EME80797.1 - 6 5.6 11.9 0.14 10.9 0.4 2.5 3 0 0 3 3 3 0 C-terminal domain of homeodomain 1 Lectin_leg-like PF03388.8 EME80799.1 - 8.4e-29 100.3 0.0 1.3e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Mst1_SARAH PF11629.3 EME80799.1 - 0.15 11.8 1.4 0.27 11.0 0.2 2.1 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 WXG100 PF06013.7 EME80799.1 - 0.28 11.2 2.7 30 4.7 0.2 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Band_7 PF01145.20 EME80800.1 - 1.4e-21 77.1 2.6 1.4e-21 77.1 1.8 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family VTC PF09359.5 EME80803.1 - 2.7e-100 335.0 0.1 2.7e-100 335.0 0.0 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EME80803.1 - 9e-23 81.4 12.3 9e-23 81.4 8.5 4.0 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 EME80803.1 - 8.6e-12 45.1 4.6 1.7e-11 44.1 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX7B PF05392.6 EME80803.1 - 0.15 11.6 0.3 0.82 9.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB DEAD PF00270.24 EME80804.1 - 2.5e-38 131.2 0.0 4.2e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME80804.1 - 1.9e-20 72.5 0.0 1.7e-19 69.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME80804.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EME80804.1 - 0.0082 15.8 0.5 0.11 12.2 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 EME80804.1 - 0.041 13.4 0.2 9.8 5.6 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.1 EME80804.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Carn_acyltransf PF00755.15 EME80804.1 - 0.13 10.2 0.1 0.2 9.6 0.1 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase AA_permease_2 PF13520.1 EME80806.1 - 9.5e-43 146.2 54.1 1.3e-42 145.8 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME80806.1 - 1.7e-19 69.5 48.3 2.2e-19 69.1 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0220 PF05255.6 EME80806.1 - 0.032 13.4 0.5 0.032 13.4 0.4 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0220) Acetyltransf_7 PF13508.1 EME80807.1 - 1.6e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME80807.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME80807.1 - 0.0031 17.6 0.0 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain EthD PF07110.6 EME80808.1 - 2.3e-15 57.2 0.1 2.9e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 EME80810.1 - 1.2e-43 149.2 0.0 1.4e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S16 PF00886.14 EME80812.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S16 Kelch_5 PF13854.1 EME80813.1 - 1.2e-17 63.4 6.1 1.1e-08 34.8 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EME80813.1 - 7e-14 51.5 9.1 9.2e-05 22.4 0.1 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EME80813.1 - 2.9e-08 33.3 16.6 0.019 14.7 0.2 6.4 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EME80813.1 - 4.1e-08 33.0 13.1 0.65 10.2 0.0 5.7 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EME80813.1 - 0.00013 21.4 9.8 0.075 12.5 0.4 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EME80813.1 - 0.00064 19.3 1.9 0.035 13.8 0.2 4.1 5 0 0 5 5 5 1 Kelch motif Mid2 PF04478.7 EME80813.1 - 0.003 16.9 0.1 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EME80813.1 - 2.7 7.4 6.1 0.37 10.1 0.7 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CVNH PF08881.5 EME80814.1 - 2.5e-30 104.7 2.2 2.8e-30 104.6 1.5 1.0 1 0 0 1 1 1 1 CVNH domain IATP PF04568.7 EME80816.1 - 1.8e-09 37.4 0.2 3.8e-09 36.4 0.0 1.6 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP DUF3661 PF12400.3 EME80817.1 - 1.2e-41 141.8 2.7 1.7e-41 141.2 1.8 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein FKBP_C PF00254.23 EME80817.1 - 4.2e-31 106.8 0.0 6.1e-31 106.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase S-antigen PF05756.6 EME80817.1 - 1.3 9.0 3.6 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 S-antigen protein MBOAT PF03062.14 EME80819.1 - 3.4e-37 128.2 13.5 3.4e-37 128.2 9.4 2.4 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EME80819.1 - 6e-06 26.2 5.6 1.6e-05 24.8 3.9 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2256 PF10013.4 EME80820.1 - 0.00039 20.1 3.5 0.0011 18.6 2.4 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.2 EME80820.1 - 0.0033 16.6 0.8 0.0064 15.7 0.6 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Zn_ribbon_recom PF13408.1 EME80820.1 - 0.36 11.1 2.5 0.84 9.9 1.7 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Fungal_trans_2 PF11951.3 EME80821.1 - 1.9e-64 217.6 1.1 2.3e-64 217.3 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME80821.1 - 1.3e-08 34.5 10.5 2.7e-08 33.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EME80822.1 - 1.1e-51 175.8 0.0 1.3e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME80822.1 - 1.9e-05 23.6 0.2 3e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EME80822.1 - 2.7e-05 23.9 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family GIDA PF01134.17 EME80822.1 - 0.00027 19.9 0.0 0.32 9.7 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EME80822.1 - 0.00033 20.5 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME80822.1 - 0.00078 19.4 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME80822.1 - 0.0021 17.8 0.7 0.15 11.8 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EME80822.1 - 0.003 17.6 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EME80822.1 - 0.0032 16.1 0.0 0.31 9.6 0.0 2.3 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_7 PF13241.1 EME80822.1 - 0.0082 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 EME80822.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EME80822.1 - 0.021 14.5 0.1 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EME80822.1 - 0.029 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EME80822.1 - 0.053 13.5 0.0 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_2 PF02615.9 EME80822.1 - 0.054 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase Thi4 PF01946.12 EME80822.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EME80822.1 - 0.1 13.0 0.1 0.31 11.4 0.0 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_4 PF07993.7 EME80823.1 - 4e-05 22.6 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EME80823.1 - 0.00023 21.1 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME80823.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Pil1 PF13805.1 EME80825.1 - 8.9e-91 303.7 6.5 1.1e-90 303.5 4.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Spectrin PF00435.16 EME80825.1 - 0.041 14.1 9.9 2.8 8.2 3.3 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF2450 PF10475.4 EME80827.1 - 0.0049 15.8 1.7 0.0049 15.8 1.2 2.1 1 1 1 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) bZIP_1 PF00170.16 EME80827.1 - 0.027 14.4 0.9 0.027 14.4 0.6 3.6 4 1 0 5 5 5 0 bZIP transcription factor DUF948 PF06103.6 EME80827.1 - 0.077 12.8 0.7 0.38 10.6 0.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 EME80827.1 - 0.22 9.8 6.4 0.17 10.2 3.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Spc42p PF11544.3 EME80827.1 - 0.41 10.5 3.2 0.5 10.3 0.3 2.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p Filament PF00038.16 EME80827.1 - 0.65 9.4 18.6 0.24 10.8 8.7 2.4 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.6 EME80827.1 - 1.9 7.0 14.4 2.8 6.4 2.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TBPIP PF07106.8 EME80827.1 - 3.2 7.2 9.4 0.31 10.5 1.8 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 EME80827.1 - 3.9 6.6 15.5 0.39 9.8 2.4 2.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4404 PF14357.1 EME80827.1 - 4.4 7.7 12.8 0.047 14.0 1.3 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) GRAM PF02893.15 EME80828.1 - 1.6e-25 88.4 1.4 2.8e-14 52.3 0.1 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EME80828.1 - 1.6e-23 83.0 0.0 3.2e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EME80828.1 - 7.3e-10 38.9 0.0 2.2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 EME80828.1 - 1.9e-05 23.4 0.0 3.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EME80828.1 - 0.034 13.8 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EME80828.1 - 0.039 13.1 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 PH_11 PF15413.1 EME80828.1 - 0.041 14.1 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Peripla_BP_6 PF13458.1 EME80828.1 - 0.17 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Asp PF00026.18 EME80829.1 - 9.1e-107 356.9 0.1 1.1e-106 356.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME80829.1 - 1.9e-13 50.6 0.0 6.6e-13 48.9 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME80829.1 - 9.2e-06 26.0 0.0 0.047 14.2 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EME80829.1 - 2e-05 24.2 0.0 0.00032 20.2 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EME80829.1 - 0.15 11.9 0.1 24 4.8 0.0 2.8 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease Glyco_trans_2_3 PF13632.1 EME80830.1 - 1.8e-22 79.9 2.7 3.2e-22 79.1 1.9 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF3254 PF11630.3 EME80830.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) NIF3 PF01784.13 EME80831.1 - 1.2e-60 205.0 0.0 1.5e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EME80832.1 - 1.8e-21 75.8 0.0 2.5e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein PaaX_C PF08223.6 EME80832.1 - 0.11 12.1 0.1 0.61 9.7 0.0 1.8 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain F-box PF00646.28 EME80833.1 - 0.00042 19.8 0.1 0.0008 18.9 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME80833.1 - 0.00092 18.8 0.8 0.0013 18.3 0.5 1.3 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EME80834.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like DUF2636 PF11120.3 EME80834.1 - 0.19 11.2 3.6 7.3 6.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) STAT_alpha PF01017.15 EME80835.1 - 0.094 12.4 0.0 4.6 6.9 0.0 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Surface_antigen PF11054.3 EME80836.1 - 0.011 15.0 1.0 0.016 14.5 0.7 1.1 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen RNA_pol_Rpb2_1 PF04563.10 EME80836.1 - 0.041 12.8 0.2 0.051 12.4 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase beta subunit DUF294_C PF10335.4 EME80836.1 - 0.12 12.0 0.4 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain TRP PF06011.7 EME80837.1 - 9.8e-133 442.9 13.8 1.2e-132 442.6 9.6 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EME80837.1 - 9.7e-39 132.6 0.4 1.8e-38 131.7 0.3 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EME80837.1 - 1.9e-05 24.8 0.2 4.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 ML domain Shisa PF13908.1 EME80837.1 - 0.0091 16.1 2.9 1.1 9.4 0.1 2.6 2 1 0 2 2 2 2 Wnt and FGF inhibitory regulator Metallophos PF00149.23 EME80838.1 - 1.6e-11 43.9 0.1 5.4e-11 42.2 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME80838.1 - 6.9e-06 25.9 0.0 3.1e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Terpene_synth_C PF03936.11 EME80840.1 - 1.7e-05 24.2 0.0 0.00014 21.1 0.0 2.1 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Asp_Glu_race_2 PF14669.1 EME80840.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative aspartate racemase Phage_Nu1 PF07471.7 EME80840.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 MFS_1 PF07690.11 EME80841.1 - 1e-40 139.5 32.7 7.6e-36 123.5 17.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME80841.1 - 1.8e-07 29.9 27.5 4.2e-07 28.7 7.6 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EME80841.1 - 3.7e-06 25.7 12.4 3.7e-06 25.7 8.6 2.6 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EME80841.1 - 0.00016 21.3 7.0 0.0019 17.9 0.2 3.8 4 0 0 4 4 4 2 MFS_1 like family LacY_symp PF01306.14 EME80841.1 - 0.00034 19.2 0.4 0.00034 19.2 0.2 2.8 3 0 0 3 3 3 1 LacY proton/sugar symporter Abhydrolase_5 PF12695.2 EME80842.1 - 4.1e-06 26.6 0.0 5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME80842.1 - 0.04 13.1 0.1 0.4 9.8 0.1 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 EME80842.1 - 0.092 11.2 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TFIIIC_delta PF12657.2 EME80843.1 - 3.3e-27 95.2 0.2 3.3e-27 95.2 0.1 2.6 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EME80843.1 - 3e-15 55.9 2.0 4.2e-15 55.4 0.3 2.0 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex Clat_adaptor_s PF01217.15 EME80844.1 - 1.1e-55 187.3 0.7 1.2e-55 187.1 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cytochrom_B561 PF03188.11 EME80846.1 - 1.3e-15 57.4 7.1 2.4e-15 56.5 4.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 SdpI PF13630.1 EME80846.1 - 0.61 9.8 14.9 0.041 13.5 1.8 3.3 1 1 3 4 4 4 0 SdpI/YhfL protein family DUF2855 PF11017.3 EME80847.1 - 9e-51 172.8 0.0 1.2e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Malic_M PF03949.10 EME80848.1 - 2.2e-85 286.3 0.0 2.8e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EME80848.1 - 7.6e-64 214.6 0.0 1.6e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1930 PF09122.5 EME80849.1 - 0.089 12.5 0.1 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) DUF4449 PF14613.1 EME80850.1 - 1.1e-05 25.4 0.2 1.1e-05 25.4 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) DUF1828 PF08861.5 EME80850.1 - 0.0012 18.4 0.1 0.017 14.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF1828 Mito_carr PF00153.22 EME80852.1 - 7.1e-47 157.0 1.5 3.7e-18 65.0 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Rab5ip PF07019.7 EME80852.1 - 0.0098 16.0 0.7 0.043 13.9 0.0 2.3 2 1 0 2 2 2 1 Rab5-interacting protein (Rab5ip) RRM_1 PF00076.17 EME80853.1 - 2.1e-49 165.0 0.0 7.7e-17 60.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME80853.1 - 9.8e-41 137.5 0.0 1.4e-14 53.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME80853.1 - 1.9e-22 78.8 0.0 1.2e-06 28.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME80853.1 - 0.002 17.9 0.0 4 7.3 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EME80853.1 - 0.0042 16.7 0.0 4.7 7.0 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 SAC3_GANP PF03399.11 EME80857.1 - 4.4e-28 98.2 0.0 6.4e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EME80857.1 - 6.7e-22 77.8 0.0 9.6e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ank_2 PF12796.2 EME80858.1 - 2e-23 82.5 1.4 5.4e-11 42.6 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME80858.1 - 8.5e-20 69.5 5.1 7.4e-09 34.9 0.4 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EME80858.1 - 2.2e-19 68.9 4.9 1.3e-09 38.0 0.4 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME80858.1 - 1.1e-15 57.6 4.6 7.2e-07 29.5 0.1 3.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME80858.1 - 3.4e-14 51.5 4.0 5.8e-05 22.9 0.1 4.5 5 0 0 5 5 5 3 Ankyrin repeat Phage_Capsid_P3 PF09018.6 EME80858.1 - 0.17 10.4 0.0 0.33 9.5 0.0 1.4 2 0 0 2 2 2 0 P3 major capsid protein polyprenyl_synt PF00348.12 EME80859.1 - 2.6e-50 170.7 0.0 2.4e-47 160.9 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EME80859.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.3 EME80860.1 - 9.1e-37 125.9 0.0 1.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Helicase_C_2 PF13307.1 EME80861.1 - 1.1e-51 175.1 0.0 2.7e-51 173.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EME80861.1 - 1.3e-35 122.3 0.1 1.5e-34 118.9 0.0 2.3 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EME80861.1 - 0.0024 17.7 0.6 0.28 11.0 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EME80861.1 - 0.036 13.2 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EME80861.1 - 0.074 13.1 0.0 9.1 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF883 PF05957.8 EME80861.1 - 1.2 9.5 8.9 6.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Pyr_redox PF00070.22 EME80863.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RasGAP PF00616.14 EME80865.1 - 3.5e-54 183.4 0.8 1.6e-53 181.2 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EME80865.1 - 6.1e-30 103.7 4.4 6.1e-30 103.7 3.0 2.8 3 0 0 3 3 3 1 RasGAP C-terminus DUF1647 PF07801.6 EME80865.1 - 0.39 10.2 4.1 0.22 11.0 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1647) X PF00739.14 EME80867.1 - 6.6 6.6 7.8 6.4 6.6 4.7 1.4 1 1 0 1 1 1 0 Trans-activation protein X Mis14 PF08641.7 EME80868.1 - 4e-13 49.6 7.2 4e-13 49.6 5.0 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Fib_alpha PF08702.5 EME80868.1 - 0.077 13.1 3.2 0.1 12.7 0.2 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3237 PF11578.3 EME80869.1 - 0.033 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) UDP-g_GGTase PF06427.6 EME80870.1 - 1.9e-62 210.3 0.0 3.3e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EME80870.1 - 0.0018 17.6 0.1 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Arginase PF00491.16 EME80871.1 - 1.4e-77 260.7 0.2 1.6e-77 260.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family FtsJ PF01728.14 EME80873.1 - 6.4e-47 159.8 0.0 8e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EME80873.1 - 0.0026 17.5 0.0 0.0048 16.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80873.1 - 0.0046 17.5 0.0 0.0076 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Dam PF05869.6 EME80873.1 - 0.053 12.9 0.2 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) MFS_1 PF07690.11 EME80874.1 - 1.8e-17 63.0 43.5 1.3e-14 53.7 12.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MRAP PF15183.1 EME80874.1 - 0.049 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Methyltransf_33 PF10017.4 EME80875.1 - 2.6e-26 91.9 0.1 3.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Pyridoxal_deC PF00282.14 EME80876.1 - 3.3e-59 200.2 0.0 4.1e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EME80876.1 - 7.8e-05 21.5 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME80876.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DAO PF01266.19 EME80877.1 - 1.4e-39 136.0 0.0 1.6e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME80877.1 - 0.00011 22.1 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EME80877.1 - 0.00023 20.9 0.0 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 ThiF family Pyr_redox_2 PF07992.9 EME80877.1 - 0.00084 19.2 0.0 3.9 7.2 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME80877.1 - 0.0055 16.4 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EME80877.1 - 0.0066 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EME80877.1 - 0.017 14.0 0.1 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 EME80877.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EME80877.1 - 0.11 12.5 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_3 PF01596.12 EME80878.1 - 3.9e-24 84.8 0.0 4.6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EME80878.1 - 9.3e-14 52.1 0.3 2.7e-13 50.6 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME80878.1 - 3.7e-13 50.0 0.1 6.7e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME80878.1 - 1.9e-10 40.5 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME80878.1 - 5e-07 29.7 0.0 8.4e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EME80878.1 - 7.7e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EME80878.1 - 8.8e-07 29.2 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EME80878.1 - 2.4e-05 23.9 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EME80878.1 - 0.0004 19.5 0.0 0.0007 18.7 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME80878.1 - 0.0024 18.2 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME80878.1 - 0.006 15.9 0.0 0.0084 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EME80878.1 - 0.0089 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME80878.1 - 0.013 15.2 0.1 0.04 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF3022 PF11226.3 EME80878.1 - 0.022 14.6 0.3 0.27 11.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3022) RrnaAD PF00398.15 EME80878.1 - 0.043 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EME80878.1 - 0.082 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 EME80879.1 - 1.5e-19 70.0 0.0 2.5e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EME80879.1 - 5e-07 30.2 0.0 7.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Saccharop_dh PF03435.13 EME80880.1 - 7.8e-99 331.2 0.0 9e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EME80880.1 - 3.9e-09 36.6 0.1 6.6e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EME80880.1 - 5.6e-06 26.4 0.2 8.8e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 EME80880.1 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EME80880.1 - 0.0061 16.8 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ferritin PF00210.19 EME80880.1 - 0.047 13.4 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Ferritin-like domain NAD_Gly3P_dh_N PF01210.18 EME80880.1 - 0.055 13.1 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2325 PF10087.4 EME80880.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) TrkA_N PF02254.13 EME80880.1 - 0.073 13.0 0.6 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 EME80880.1 - 0.074 13.3 0.3 0.17 12.1 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Adeno_PX PF05829.7 EME80881.1 - 0.011 15.2 0.3 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 Adenovirus late L2 mu core protein (Protein X) DUSP PF06337.7 EME80881.1 - 0.052 13.9 1.3 0.074 13.4 0.1 2.0 2 1 0 2 2 2 0 DUSP domain RabGAP-TBC PF00566.13 EME80883.1 - 2.1e-35 122.1 0.0 3.1e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ammonium_transp PF00909.16 EME80884.1 - 1.1e-114 383.0 25.4 1.3e-114 382.8 17.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM213 PF15192.1 EME80884.1 - 0.063 13.2 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 TMEM213 family Glyco_hydro_cc PF11790.3 EME80885.1 - 8.5e-70 234.8 4.6 9.8e-70 234.6 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 EME80885.1 - 0.0023 17.6 0.8 0.0047 16.6 0.2 1.7 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain Pol_alpha_B_N PF08418.5 EME80886.1 - 0.023 14.2 3.3 0.032 13.7 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PAP2 PF01569.16 EME80888.1 - 5.8e-13 48.6 4.7 5.8e-13 48.6 3.2 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EME80888.1 - 1.4e-07 31.2 5.1 1.4e-07 31.2 3.5 1.7 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_L11_N PF03946.9 EME80890.1 - 7.7e-27 92.5 0.1 1.5e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EME80890.1 - 3.5e-18 65.4 0.9 3.5e-18 65.4 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain DUF4506 PF14958.1 EME80891.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) Cep57_MT_bd PF06657.8 EME80891.1 - 0.034 14.1 0.6 0.061 13.2 0.4 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Drc1-Sld2 PF11719.3 EME80892.1 - 1.9e-79 267.8 26.2 2.2e-79 267.5 18.2 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-C2H2 PF00096.21 EME80893.1 - 5.9e-05 23.1 17.3 0.18 12.2 0.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME80893.1 - 0.00014 21.9 13.5 0.019 15.2 1.8 3.7 3 0 0 3 3 3 2 Zinc-finger double domain Bunya_G2 PF03563.8 EME80893.1 - 0.18 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Alpha_GJ PF03229.8 EME80893.1 - 1.8 8.8 8.3 16 5.8 1.6 2.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J zf-C2H2_4 PF13894.1 EME80893.1 - 3.5 8.1 17.7 0.95 9.9 0.1 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EME80893.1 - 9.4 6.2 8.3 4.6 7.2 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger ubiquitin PF00240.18 EME80894.1 - 1.6e-34 117.0 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EME80894.1 - 1.4e-27 95.2 2.5 2.9e-27 94.2 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EME80894.1 - 5.9e-20 70.7 0.7 1.1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME80894.1 - 8.7e-06 25.9 0.2 4.1e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME80894.1 - 0.00013 21.7 0.1 0.00021 21.0 0.0 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EME80894.1 - 0.0016 18.2 0.6 0.0035 17.1 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME80894.1 - 0.0044 17.1 0.5 0.0062 16.7 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EME80894.1 - 0.043 13.8 0.8 0.077 13.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 EME80894.1 - 0.082 11.4 0.3 0.087 11.3 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 EME80894.1 - 0.099 10.9 2.5 2.3 6.4 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 EME80894.1 - 0.12 12.2 0.4 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 IBR domain CLU PF13236.1 EME80895.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Clustered mitochondria DUF694 PF05107.7 EME80896.1 - 1.5 7.9 4.6 6.9 5.8 0.3 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF694) WD40 PF00400.27 EME80897.1 - 9e-09 34.8 3.6 0.0023 17.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat YL1 PF05764.8 EME80897.1 - 4.8 6.7 14.3 9.1 5.8 9.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Viral_cys_rich PF08008.7 EME80899.1 - 0.13 11.8 1.0 0.16 11.5 0.7 1.3 1 0 0 1 1 1 0 Viral cysteine rich Hexokinase_2 PF03727.11 EME80900.1 - 1.6e-88 296.0 0.0 2.1e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EME80900.1 - 4.2e-76 254.8 0.0 5.5e-74 247.9 0.0 2.1 2 0 0 2 2 2 2 Hexokinase LCM PF04072.9 EME80901.1 - 1.6e-24 86.4 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF390 PF04094.9 EME80903.1 - 0.0014 16.7 4.0 0.0016 16.6 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF390) DXP_synthase_N PF13292.1 EME80903.1 - 0.0077 15.1 1.5 0.0097 14.8 1.1 1.1 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Met_synt_B12 PF02965.12 EME80903.1 - 0.013 14.6 2.1 0.016 14.3 1.5 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain PA26 PF04636.8 EME80903.1 - 0.029 13.1 3.1 0.034 12.8 2.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CT47 PF15623.1 EME80903.1 - 0.062 13.0 8.9 0.073 12.8 6.2 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 SAP PF02037.22 EME80903.1 - 0.068 12.7 0.1 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 SAP domain Latarcin PF10279.4 EME80903.1 - 0.21 11.8 8.2 0.15 12.2 1.6 2.3 1 1 1 2 2 2 0 Latarcin precursor CMV_1a PF12467.3 EME80903.1 - 0.23 11.8 6.3 0.32 11.3 4.4 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family HSP70 PF00012.15 EME80903.1 - 2.3 6.0 9.3 2.8 5.7 6.5 1.1 1 0 0 1 1 1 0 Hsp70 protein Bud13 PF09736.4 EME80903.1 - 3.5 7.8 7.5 5 7.3 5.2 1.4 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF4359 PF14271.1 EME80903.1 - 3.6 8.0 5.1 1.7 9.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) DUF3708 PF12501.3 EME80903.1 - 4.8 7.0 7.5 7.2 6.4 5.2 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Sec62 PF03839.11 EME80903.1 - 7.3 5.9 6.7 9.4 5.5 4.3 1.3 1 1 0 1 1 1 0 Translocation protein Sec62 Glyco_hydro_76 PF03663.9 EME80907.1 - 6.6e-49 167.2 12.2 8.4e-49 166.9 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Fungal_trans PF04082.13 EME80908.1 - 5.7e-20 71.2 0.0 1.4e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain PP-binding PF00550.20 EME80910.1 - 1.3e-11 44.6 0.4 1.7e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EME80910.1 - 3.3e-06 27.0 0.1 5.3e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 EME80910.1 - 0.075 13.0 0.1 0.53 10.2 0.0 1.9 1 1 1 2 2 2 0 Ribosomal subunit 39S GPP34 PF05719.6 EME80911.1 - 4.8e-67 226.0 1.2 5.7e-67 225.7 0.9 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) p450 PF00067.17 EME80913.1 - 3.4e-58 197.2 0.0 5.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EME80914.1 - 7.6e-12 44.5 0.1 9.7e-12 44.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME80914.1 - 9.2e-09 35.0 10.7 1.6e-08 34.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2666 PF10869.3 EME80915.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) MFS_1 PF07690.11 EME80917.1 - 1.5e-11 43.6 2.3 1.5e-11 43.5 1.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3784 PF12650.2 EME80917.1 - 0.054 13.4 0.5 0.082 12.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) MFS_Mycoplasma PF07672.8 EME80917.1 - 0.058 12.5 3.0 0.068 12.3 2.1 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter Mid2 PF04478.7 EME80919.1 - 0.049 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Acyl_transf_3 PF01757.17 EME80920.1 - 1.9e-34 119.0 43.3 2.2e-34 118.7 30.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 EME80921.1 - 3.5e-12 46.6 0.1 7.7e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif 5_nucleotid_C PF02872.13 EME80922.1 - 7.4e-37 126.7 0.1 1.9e-36 125.4 0.1 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EME80922.1 - 4e-08 32.8 1.2 1.1e-07 31.4 0.5 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 EME80922.1 - 0.01 14.9 0.1 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 YmdB-like protein Bac_luciferase PF00296.15 EME80923.1 - 3.1e-60 203.9 0.2 4.3e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase F-box-like PF12937.2 EME80924.1 - 0.0034 17.0 0.3 0.0099 15.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like NIF PF03031.13 EME80925.1 - 1.6e-28 99.4 0.0 3.6e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EME80925.1 - 5.7e-08 32.4 0.8 1.6e-07 31.0 0.6 1.9 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EME80925.1 - 1.4e-07 31.5 0.1 4.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Methyltransf_18 PF12847.2 EME80926.1 - 5.6e-11 43.0 0.0 1.1e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME80926.1 - 0.00025 21.3 0.0 0.00062 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME80926.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EME80926.1 - 0.0011 19.7 0.0 0.0025 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME80926.1 - 0.0084 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME80926.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EME80926.1 - 0.029 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EME80926.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EME80927.1 - 2.3e-68 230.5 0.0 6.3e-53 179.6 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EME80927.1 - 9.5e-14 52.1 0.0 3.2e-13 50.4 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BTB PF00651.26 EME80929.1 - 3.1e-09 36.7 0.0 4.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EME80930.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF3554 PF12074.3 EME80931.1 - 2.8e-74 250.5 6.6 6.7e-73 246.0 1.3 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EME80931.1 - 3.3e-30 101.4 46.3 0.015 15.2 0.0 22.6 24 0 0 24 24 24 8 HEAT repeat HEAT_EZ PF13513.1 EME80931.1 - 8.7e-30 102.4 70.8 9.9e-07 29.0 0.0 23.1 17 3 11 28 28 26 8 HEAT-like repeat HEAT_2 PF13646.1 EME80931.1 - 5.7e-29 100.2 79.3 1.7e-10 41.0 0.1 17.0 8 4 6 15 15 14 8 HEAT repeats Adaptin_N PF01602.15 EME80931.1 - 1.8e-12 46.3 0.8 8.6e-05 21.0 0.0 6.4 7 2 1 8 8 8 3 Adaptin N terminal region ParcG PF10274.4 EME80931.1 - 2e-10 40.8 2.6 0.0089 15.9 0.0 6.2 6 1 1 7 7 7 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 EME80931.1 - 2.3e-09 37.5 0.4 8.9 6.7 0.0 9.0 8 2 3 11 11 10 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EME80931.1 - 2.3e-09 37.3 0.2 0.37 10.6 0.0 7.7 7 2 1 9 9 8 2 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 EME80931.1 - 5.3e-05 23.1 1.8 0.39 10.6 0.0 6.8 7 0 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation UME PF08064.8 EME80931.1 - 0.00015 21.6 3.3 4.2 7.3 0.0 7.5 7 2 5 12 12 12 1 UME (NUC010) domain Cohesin_HEAT PF12765.2 EME80931.1 - 0.0053 16.6 13.6 8.1 6.5 0.1 7.4 7 0 0 7 7 7 1 HEAT repeat associated with sister chromatid cohesion Hyccin PF09790.4 EME80931.1 - 0.016 14.0 0.2 0.12 11.2 0.1 2.2 2 0 0 2 2 2 0 Hyccin Vitellogenin_N PF01347.17 EME80931.1 - 0.049 11.8 0.1 0.11 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein amino terminal region Nucleotid_trans PF03407.11 EME80931.1 - 0.3 10.8 0.0 1.1 9.0 0.0 1.8 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase HA2 PF04408.18 EME80933.1 - 2.4e-19 69.2 0.1 6.8e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME80933.1 - 1.9e-13 50.0 0.1 5.4e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME80933.1 - 2.8e-08 33.4 0.1 6.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME80933.1 - 1.3e-07 31.8 0.1 4.6e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EME80933.1 - 0.0063 16.8 0.0 0.05 13.8 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EME80933.1 - 0.021 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EME80933.1 - 0.052 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME80933.1 - 0.38 11.0 0.0 0.38 11.0 0.0 2.6 4 0 0 4 4 4 0 AAA domain RAP1 PF07218.6 EME80933.1 - 4.5 5.2 4.0 6.6 4.7 2.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_L19e PF01280.15 EME80934.1 - 2.9e-61 205.5 9.3 2.9e-61 205.5 6.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e Endonuc_Holl PF10107.4 EME80934.1 - 0.64 9.6 3.8 1.2 8.7 2.6 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase 2H-phosphodiest PF08975.5 EME80937.1 - 0.045 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) KTI12 PF08433.5 EME80937.1 - 0.1 11.7 0.0 11 5.1 0.1 2.3 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Nucleotid_trans PF03407.11 EME80937.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Bombesin PF02044.12 EME80938.1 - 0.59 9.6 2.6 1.4 8.4 1.8 1.6 1 0 0 1 1 1 0 Bombesin-like peptide SRP14 PF02290.10 EME80943.1 - 2.2e-26 91.6 0.0 2.2e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.3 EME80943.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 MIF4G PF02854.14 EME80944.1 - 8e-16 58.0 0.2 1.4e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EME80944.1 - 3.2e-14 52.6 0.0 7.3e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 MA3 domain Ribosomal_L27e PF01777.13 EME80946.1 - 5.5e-37 125.7 3.2 7e-37 125.4 2.2 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EME80946.1 - 0.011 15.4 1.2 0.018 14.7 0.1 1.9 2 0 0 2 2 2 0 KOW motif PH_6 PF15406.1 EME80947.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Cupin_7 PF12973.2 EME80949.1 - 0.0002 21.1 0.1 0.00027 20.7 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.6 EME80949.1 - 0.067 12.6 1.4 0.17 11.3 1.0 1.8 1 1 0 1 1 1 0 Cupin domain ADH_zinc_N PF00107.21 EME80950.1 - 2.4e-06 27.1 0.1 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Patatin PF01734.17 EME80953.1 - 5.7e-20 72.1 0.0 4.6e-19 69.1 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Epimerase PF01370.16 EME80954.1 - 6.9e-05 22.3 0.0 8.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME80954.1 - 0.00032 20.7 0.4 0.00062 19.8 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME80954.1 - 0.003 16.2 0.0 0.0049 15.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ten_N PF06484.7 EME80954.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Teneurin Intracellular Region SHNi-TPR PF10516.4 EME80955.1 - 2.4e-14 52.2 0.4 4.7e-14 51.3 0.3 1.5 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 EME80955.1 - 0.0051 16.7 2.2 0.0067 16.3 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME80955.1 - 0.045 13.3 1.3 0.51 10.0 0.2 2.6 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EME80955.1 - 0.69 9.9 4.0 0.82 9.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 EME80955.1 - 2.1 8.7 7.3 5.6 7.3 0.7 3.2 3 1 0 3 3 3 0 Snapin/Pallidin CRT10 PF08728.5 EME80955.1 - 2.4 6.0 4.4 3.3 5.5 3.0 1.3 1 0 0 1 1 1 0 CRT10 FUSC PF04632.7 EME80955.1 - 2.5 6.4 7.1 3.4 5.9 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DNA_pol_E_B PF04042.11 EME80956.1 - 9.2e-47 158.9 0.0 1.4e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TIR PF01582.15 EME80956.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 TIR domain YrhK PF14145.1 EME80961.1 - 1.4e-07 31.0 9.3 4.7e-05 22.9 0.7 3.0 2 1 0 2 2 2 2 YrhK-like protein DUF4231 PF14015.1 EME80961.1 - 0.0037 17.2 0.2 0.0095 15.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Fungal_trans PF04082.13 EME80962.1 - 6.9e-11 41.5 0.0 8.5e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L18e PF00828.14 EME80964.1 - 2.3e-24 86.1 0.1 3.5e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 AIRC PF00731.15 EME80965.1 - 5.7e-57 191.2 1.1 9.5e-57 190.4 0.8 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EME80965.1 - 7e-51 171.9 0.0 1.3e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 EME80965.1 - 0.0014 17.8 0.1 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 EME80965.1 - 0.0017 18.6 0.1 0.061 13.6 0.0 2.4 2 0 0 2 2 2 1 XdhC Rossmann domain VirE_N PF08800.5 EME80965.1 - 0.0027 17.4 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 VirE N-terminal domain Dala_Dala_lig_C PF07478.8 EME80965.1 - 0.018 14.4 0.0 0.097 12.0 0.0 2.1 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus DNase_NucA_NucB PF14040.1 EME80967.1 - 9.4e-06 25.7 5.2 8.2e-05 22.7 3.6 2.3 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF3471 PF11954.3 EME80970.1 - 3.3e-06 26.8 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.19 EME80971.1 - 3.4e-11 42.7 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase GBV-C_env PF12786.2 EME80971.1 - 0.0001 20.8 0.0 0.00011 20.7 0.0 1.2 1 0 0 1 1 1 1 GB virus C genotype envelope TPR_12 PF13424.1 EME80972.1 - 1.9e-12 46.9 5.5 1.1e-11 44.4 3.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME80972.1 - 2.6e-10 39.8 5.0 0.00031 20.5 1.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME80972.1 - 6.1e-10 38.2 4.3 2.2e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.17 EME80972.1 - 3.2e-09 36.0 0.0 4.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EME80972.1 - 7.6e-09 34.7 1.8 0.0026 17.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME80972.1 - 1.6e-08 33.7 1.6 3.8e-05 23.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME80972.1 - 9e-06 25.2 6.0 3.1e-05 23.5 4.1 2.0 1 1 0 1 1 1 1 TPR repeat TPR_8 PF13181.1 EME80972.1 - 0.00023 20.7 1.0 0.0064 16.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EME80972.1 - 0.0033 16.6 2.3 0.078 12.2 0.2 2.4 2 0 0 2 2 2 1 SHNi-TPR AAA_22 PF13401.1 EME80972.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.1 EME80972.1 - 0.037 14.2 3.2 1.5 9.1 0.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME80972.1 - 0.056 14.0 2.8 1.1 10.0 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Fer4_NifH PF00142.13 EME80972.1 - 0.057 12.5 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FmdA_AmdA PF03069.10 EME80975.1 - 7.3e-134 446.0 0.0 1.1e-133 445.5 0.0 1.2 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 EME80976.1 - 9.5e-05 21.9 16.0 0.00027 20.4 1.9 3.0 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 EME80977.1 - 1.1e-26 93.2 0.0 7.2e-26 90.6 0.0 2.4 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 DNA_methylase PF00145.12 EME80979.1 - 3.7e-32 111.7 0.0 3.3e-31 108.6 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EME80979.1 - 1.6e-05 24.6 0.0 0.0006 19.5 0.0 2.5 2 1 0 2 2 2 1 BAH domain DNMT1-RFD PF12047.3 EME80979.1 - 0.0074 15.9 0.2 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DUF2517 PF10725.4 EME80979.1 - 2.1 8.0 7.1 1.2 8.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) RED_N PF07808.8 EME80986.1 - 4.1e-08 32.7 6.0 4.1e-08 32.7 4.2 3.1 2 1 1 3 3 3 1 RED-like protein N-terminal region PI3K_1B_p101 PF10486.4 EME80986.1 - 1.4 6.3 9.9 2.2 5.7 6.8 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.20 EME80987.1 - 2e-44 151.6 0.0 1.4e-41 142.3 0.0 3.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME80987.1 - 2.1e-14 53.2 0.0 4.9e-11 42.1 0.0 3.5 2 2 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME80987.1 - 0.022 13.7 0.0 1.2 7.9 0.0 2.4 3 0 0 3 3 3 0 Kinase-like APH PF01636.18 EME80987.1 - 0.029 14.1 0.0 0.51 10.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EME80987.1 - 0.063 12.3 0.1 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-B_dimeris PF09026.5 EME80987.1 - 8.7 6.6 7.6 1.5 9.0 0.1 2.4 1 1 1 2 2 2 0 Centromere protein B dimerisation domain Cnd1 PF12717.2 EME80988.1 - 1.1e-52 178.4 3.9 2.6e-48 164.2 0.2 3.3 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EME80988.1 - 9.7e-50 168.5 3.1 1e-48 165.1 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EME80988.1 - 1.5e-11 44.4 1.5 0.0051 17.0 0.0 5.9 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EME80988.1 - 1.5e-06 27.7 4.9 0.067 13.3 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EME80988.1 - 0.00064 20.1 2.7 11 6.6 0.1 5.3 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EME80988.1 - 0.032 14.2 0.1 16 5.5 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion MFS_1 PF07690.11 EME80989.1 - 2e-28 99.1 74.5 7.9e-22 77.4 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME80989.1 - 0.018 13.6 43.8 0.37 9.3 10.1 3.1 2 1 0 2 2 2 0 Sugar (and other) transporter Cu_amine_oxid PF01179.15 EME80990.1 - 3.2e-164 546.5 0.2 3.9e-164 546.2 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EME80990.1 - 1.8e-07 31.1 0.0 3.9e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EME80990.1 - 6.7e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain THOC7 PF05615.8 EME80991.1 - 7.8e-27 94.2 7.0 7.8e-27 94.2 4.8 1.7 1 1 1 2 2 2 1 Tho complex subunit 7 DUF241 PF03087.9 EME80991.1 - 0.0005 19.6 4.0 0.00076 19.0 2.8 1.3 1 0 0 1 1 1 1 Arabidopsis protein of unknown function DUF3829 PF12889.2 EME80991.1 - 0.011 15.0 5.2 0.013 14.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Atg14 PF10186.4 EME80991.1 - 0.018 14.0 3.3 0.021 13.8 2.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 EME80991.1 - 0.025 14.3 4.1 0.045 13.5 2.9 1.3 1 0 0 1 1 1 0 Laminin Domain II TPR_MLP1_2 PF07926.7 EME80991.1 - 0.058 13.1 10.5 0.1 12.3 7.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 EME80991.1 - 0.12 12.3 12.4 0.07 13.1 6.0 2.2 2 0 0 2 2 2 0 DivIVA protein AAA_23 PF13476.1 EME80991.1 - 0.27 11.5 4.3 0.4 10.9 3.0 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.8 EME80991.1 - 2.6 7.0 4.8 3.5 6.6 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein SYCE1 PF15233.1 EME80991.1 - 2.8 7.8 13.2 3.2 7.6 2.5 2.7 2 1 1 3 3 3 0 Synaptonemal complex central element protein 1 DUF1929 PF09118.6 EME80992.1 - 1.6e-26 92.2 0.3 3.5e-26 91.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.6 EME80992.1 - 5.8e-17 61.5 0.0 6.2e-12 45.1 0.0 2.6 1 1 1 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 EME80992.1 - 0.00014 21.4 0.6 27 4.7 0.0 5.3 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 EME80992.1 - 0.00016 21.1 0.2 0.5 9.9 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 EME80992.1 - 0.00047 20.2 3.2 9 6.6 0.2 5.7 4 2 2 6 6 6 1 Kelch motif Kelch_4 PF13418.1 EME80992.1 - 0.0012 18.5 4.1 0.37 10.5 0.1 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Elongin_A PF06881.6 EME80993.1 - 7.5e-17 61.6 1.0 7.5e-17 61.6 0.7 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ATP-synt_G PF04718.10 EME80993.1 - 0.43 11.2 3.3 16 6.1 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit TBCA PF02970.11 EME80994.1 - 3.6e-23 81.4 10.8 4.4e-23 81.1 7.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A HlyD PF00529.15 EME80994.1 - 0.054 12.7 11.3 0.063 12.5 7.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF2570 PF10828.3 EME80994.1 - 0.08 12.5 5.0 0.1 12.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ERM PF00769.14 EME80994.1 - 0.084 12.3 11.4 0.097 12.1 7.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LUC7 PF03194.10 EME80994.1 - 0.11 11.9 4.8 0.05 13.1 1.6 1.5 1 1 0 1 1 1 0 LUC7 N_terminus HSP70 PF00012.15 EME80994.1 - 0.15 9.9 6.8 0.17 9.7 4.7 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4358 PF14270.1 EME80994.1 - 0.16 11.8 5.2 0.32 10.8 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4358) Exonuc_VII_L PF02601.10 EME80994.1 - 0.44 9.6 5.0 0.49 9.5 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Methyltransf_14 PF08484.6 EME80994.1 - 0.62 9.5 3.0 0.78 9.2 1.7 1.4 1 1 0 1 1 1 0 C-methyltransferase C-terminal domain Atg14 PF10186.4 EME80994.1 - 0.67 8.8 9.0 0.83 8.5 6.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2681 PF10883.3 EME80994.1 - 0.7 10.1 11.1 0.16 12.1 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) SpoIIIAH PF12685.2 EME80994.1 - 1.7 8.1 8.7 2 7.8 6.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein V_ATPase_I PF01496.14 EME80994.1 - 1.9 6.2 4.4 1.9 6.2 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EME80994.1 - 2.9 6.8 9.1 3.4 6.6 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4404 PF14357.1 EME80994.1 - 3.4 8.1 6.9 0.47 10.9 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Mnd1 PF03962.10 EME80994.1 - 4.3 6.9 12.3 6.9 6.2 8.5 1.4 1 1 0 1 1 1 0 Mnd1 family Bap31 PF05529.7 EME80994.1 - 8.6 5.7 9.7 7.3 6.0 6.1 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like MCM PF00493.18 EME80995.1 - 5.6e-139 462.5 0.0 7.5e-139 462.1 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME80995.1 - 1.2e-20 74.1 0.0 6.5e-20 71.8 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EME80995.1 - 8.2e-06 25.5 0.1 0.00012 21.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EME80995.1 - 1.1e-05 24.6 0.0 0.00025 20.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EME80995.1 - 0.00095 18.7 0.0 0.0023 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EME80995.1 - 0.021 13.4 0.3 0.021 13.4 0.2 1.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EME80995.1 - 0.082 12.3 0.1 4 6.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain ubiquitin PF00240.18 EME80996.1 - 1.4e-26 91.6 0.0 1.5e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME80996.1 - 4.7e-19 67.8 0.1 5.3e-19 67.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME80996.1 - 6.8e-06 26.2 0.0 2.3e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EME80996.1 - 0.022 14.6 0.1 0.067 13.0 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CTDII PF01556.13 EME80996.1 - 0.14 12.1 0.4 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 DnaJ C terminal domain Chisel PF15355.1 EME80997.1 - 0.69 9.9 2.7 1.5 8.8 1.9 1.6 1 1 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel Ras PF00071.17 EME81001.1 - 1.5e-53 180.4 0.1 5.1e-53 178.7 0.1 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EME81001.1 - 4.9e-18 65.7 0.0 4.3e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME81001.1 - 2.3e-05 23.7 0.0 0.00026 20.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME81001.1 - 0.0017 17.7 0.1 2.9 7.2 0.0 2.9 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME81001.1 - 0.0041 17.0 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EME81001.1 - 0.04 13.0 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.13 EME81001.1 - 0.054 12.5 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_25 PF13481.1 EME81001.1 - 0.057 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EME81001.1 - 0.087 12.0 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B CbiA PF01656.18 EME81001.1 - 0.16 11.3 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HAD_2 PF13419.1 EME81002.1 - 1.9e-28 99.8 0.0 2.7e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME81002.1 - 5e-11 43.4 0.0 7.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME81002.1 - 4.6e-07 29.4 0.1 1.1e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Histone PF00125.19 EME81003.1 - 1e-15 57.5 0.1 1.2e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EME81003.1 - 6.9e-05 22.7 0.1 9.9e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EME81003.1 - 7.9e-05 22.7 0.1 0.00011 22.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EME81003.1 - 0.00011 22.2 0.1 0.0002 21.3 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME81003.1 - 0.012 15.3 0.0 0.015 14.9 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EME81003.1 - 0.015 14.5 0.0 0.015 14.5 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EME81003.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EME81004.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME81004.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EME81004.1 - 0.0042 17.0 0.4 0.0073 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME81004.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Mpv17_PMP22 PF04117.7 EME81005.1 - 2.1e-17 62.4 2.5 2.1e-17 62.4 1.7 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family Exo5 PF09810.4 EME81006.1 - 4.1e-101 338.4 0.1 4.8e-101 338.2 0.1 1.0 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EME81006.1 - 0.0062 15.9 1.1 0.056 12.8 0.9 2.4 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Fer4 PF00037.22 EME81008.1 - 5.8e-14 51.0 16.4 3.2e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EME81008.1 - 2.8e-12 46.8 10.8 4.5e-12 46.1 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EME81008.1 - 2.4e-10 40.0 23.6 2.3e-08 33.6 9.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EME81008.1 - 8.3e-10 38.3 4.7 6e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EME81008.1 - 1.2e-09 38.2 11.5 2.8e-09 37.0 8.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EME81008.1 - 2.9e-09 37.5 9.8 5.8e-05 23.7 0.3 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 EME81008.1 - 3e-08 33.5 21.2 1.3e-05 25.1 8.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EME81008.1 - 1.2e-07 31.1 14.3 0.0006 19.5 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EME81008.1 - 5.7e-07 29.3 12.8 0.00058 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EME81008.1 - 6.4e-07 28.9 17.4 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EME81008.1 - 3.5e-06 27.2 10.5 0.00079 19.7 8.2 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EME81008.1 - 4.5e-05 23.7 10.0 0.013 15.8 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EME81008.1 - 0.0074 16.8 13.1 0.34 11.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EME81008.1 - 0.008 16.5 15.6 0.3 11.4 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EME81008.1 - 0.019 15.4 17.5 0.041 14.4 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EME81008.1 - 0.077 13.1 5.5 0.37 10.9 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_11 PF13247.1 EME81008.1 - 0.16 11.8 4.5 0.29 11.0 3.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain NTP_transf_2 PF01909.18 EME81010.1 - 0.00038 20.7 0.0 0.0015 18.8 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Glyco_transf_20 PF00982.16 EME81011.1 - 4.5e-147 490.3 0.0 6.4e-147 489.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EME81011.1 - 1e-90 302.7 0.0 1.6e-90 302.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.2 EME81011.1 - 0.011 15.8 0.0 0.14 12.2 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.15 EME81011.1 - 0.2 11.0 0.0 9.2 5.6 0.0 2.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 Peptidase_M24 PF00557.19 EME81012.1 - 1.2e-09 38.0 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 EME81013.1 - 2.4e-15 55.9 19.1 1.8e-09 37.0 4.0 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 EME81013.1 - 0.0076 16.3 6.3 0.026 14.6 0.4 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain Staphylokinase PF02821.11 EME81013.1 - 0.0092 15.7 1.3 0.015 15.1 0.3 1.7 2 0 0 2 2 2 1 Staphylokinase/Streptokinase family zf-PHD-like PF15446.1 EME81013.1 - 0.21 10.8 10.1 1.4 8.2 1.2 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EME81013.1 - 2.1 8.1 14.0 1.3 8.8 3.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EME81013.1 - 2.3 8.2 10.0 3 7.9 0.8 2.6 2 0 0 2 2 2 0 RING-like domain C1_1 PF00130.17 EME81013.1 - 6.4 6.5 17.9 4.9 6.9 2.9 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF5 PF04855.7 EME81014.1 - 8.2e-68 228.4 2.3 1.4e-67 227.7 1.6 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Gar1 PF04410.9 EME81019.1 - 1.1e-44 151.6 1.9 1.1e-44 151.6 1.3 2.6 2 0 0 2 2 2 2 Gar1/Naf1 RNA binding region Prenyltrans PF00432.16 EME81019.1 - 0.11 12.1 0.2 0.3 10.6 0.1 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Glyco_transf_22 PF03901.12 EME81020.1 - 4.4e-80 269.7 19.7 5.2e-80 269.4 13.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3445 PF11927.3 EME81021.1 - 6.9e-17 61.6 0.0 8.9e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 EME81023.1 - 5.8e-49 166.7 2.6 7.8e-49 166.2 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81023.1 - 1.1e-09 38.0 12.0 2.1e-09 37.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PCEMA1 PF07418.6 EME81023.1 - 0.15 11.4 1.2 0.22 10.8 0.8 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 AT_hook PF02178.14 EME81023.1 - 1.7 8.5 7.6 3.6 7.5 5.3 1.6 1 0 0 1 1 1 0 AT hook motif DUF3824 PF12868.2 EME81024.1 - 7.7e-16 59.2 30.5 7.7e-16 59.2 21.1 10.8 6 3 6 12 12 12 2 Domain of unknwon function (DUF3824) Voltage_CLC PF00654.15 EME81024.1 - 0.41 9.5 1.0 0.97 8.3 0.7 1.6 1 0 0 1 1 1 0 Voltage gated chloride channel 2Fe-2S_thioredx PF01257.14 EME81025.1 - 2.1e-61 205.7 0.1 2.8e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SBP_bac_7 PF03480.8 EME81025.1 - 0.13 11.3 0.0 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 EI24 PF07264.6 EME81027.1 - 1.6e-05 24.4 14.3 7.2e-05 22.3 9.9 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.4 EME81027.1 - 2.2 6.7 5.0 0.64 8.5 1.3 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CcoS PF03597.10 EME81027.1 - 6.3 6.3 6.1 3 7.3 0.5 2.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Pyr_redox_dim PF02852.17 EME81029.1 - 2.4e-40 136.9 0.1 8.4e-40 135.2 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EME81029.1 - 1e-39 136.5 7.2 2.7e-39 135.1 5.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME81029.1 - 5.3e-24 84.4 8.3 7.9e-20 71.0 0.4 3.2 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME81029.1 - 7e-11 41.9 4.6 2e-06 27.7 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME81029.1 - 2e-10 40.3 4.1 5.1e-10 39.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME81029.1 - 6e-10 39.5 0.2 3.1e-06 27.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME81029.1 - 5.3e-09 35.4 10.6 2.8e-07 29.7 3.8 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EME81029.1 - 7.1e-08 31.7 17.4 3.6e-05 22.8 2.7 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME81029.1 - 1.6e-07 30.5 2.6 1.6e-07 30.5 1.8 2.7 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EME81029.1 - 4.9e-07 28.5 14.0 4.2e-05 22.1 1.2 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EME81029.1 - 1.5e-06 27.3 1.2 0.034 13.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EME81029.1 - 1.6e-06 27.4 2.6 9.6e-06 24.8 0.1 2.5 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EME81029.1 - 2e-05 24.1 2.4 0.051 13.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EME81029.1 - 0.0022 16.9 1.8 0.013 14.4 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EME81029.1 - 0.003 17.8 1.0 2 8.7 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EME81029.1 - 0.0075 15.3 9.3 0.14 11.1 0.9 3.0 2 1 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 EME81029.1 - 0.018 14.6 5.9 0.043 13.4 0.3 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EME81029.1 - 0.09 11.9 0.9 8.8 5.4 0.2 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EME81029.1 - 0.11 11.1 6.4 0.09 11.3 0.7 2.3 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EME81029.1 - 0.11 11.8 4.5 0.51 9.6 0.2 2.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.14 EME81029.1 - 0.21 9.7 3.3 0.17 10.0 0.5 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like F420_oxidored PF03807.12 EME81029.1 - 4.5 7.7 6.2 16 6.0 0.1 3.5 4 0 0 4 4 3 0 NADP oxidoreductase coenzyme F420-dependent tRNA-synt_2 PF00152.15 EME81030.1 - 1.4e-72 244.3 0.1 1.4e-72 244.3 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME81030.1 - 1.9e-10 40.4 0.0 3.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mo25 PF08569.6 EME81032.1 - 3.4e-114 381.3 0.1 3.8e-114 381.2 0.1 1.0 1 0 0 1 1 1 1 Mo25-like HATPase_c PF02518.21 EME81033.1 - 5.4e-26 90.4 0.1 9.8e-26 89.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME81033.1 - 8.2e-20 70.5 0.1 2.7e-19 68.9 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EME81033.1 - 1.3e-19 70.1 0.8 3.4e-11 43.0 0.4 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.19 EME81033.1 - 1.3e-18 67.0 0.0 3.5e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EME81033.1 - 5e-16 58.9 0.0 5.3e-12 46.0 0.0 3.3 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 EME81033.1 - 5.3e-13 48.7 0.0 1.8e-06 27.7 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EME81033.1 - 1.1e-11 44.6 1.1 1.5e-08 34.5 0.0 3.9 4 0 0 4 4 4 2 PAS fold MFS_1 PF07690.11 EME81034.1 - 5.2e-23 81.3 41.3 1.7e-22 79.6 28.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.1 EME81034.1 - 0.043 13.2 14.0 0.12 11.7 1.4 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 EME81035.1 - 3.3e-39 134.5 0.0 4.6e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81035.1 - 2.7e-15 56.1 0.0 3.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME81035.1 - 0.00044 19.3 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME81035.1 - 0.0016 18.2 0.3 0.04 13.6 0.2 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EME81035.1 - 0.0032 16.5 0.0 0.0061 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.21 EME81036.1 - 2e-48 164.1 0.2 2.5e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EME81036.1 - 0.037 13.1 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) FAD_binding_4 PF01565.18 EME81037.1 - 2.8e-23 81.9 0.3 4.9e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.2 EME81038.1 - 0.025 14.2 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like SWI-SNF_Ssr4 PF08549.5 EME81039.1 - 3.7e-120 402.2 8.0 4.1e-120 402.1 5.5 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) DivIVA PF05103.8 EME81039.1 - 0.08 12.9 2.1 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 DivIVA protein DUF1993 PF09351.5 EME81040.1 - 8.6e-53 178.5 0.0 9.7e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) adh_short PF00106.20 EME81041.1 - 0.1 12.4 0.0 3.9 7.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase MOZ_SAS PF01853.13 EME81042.1 - 3.2e-60 202.5 0.0 4.4e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Amino_oxidase PF01593.19 EME81045.1 - 2.8e-55 188.1 0.1 1.1e-35 123.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME81045.1 - 2.6e-16 59.3 0.4 6.1e-16 58.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME81045.1 - 5.7e-08 33.0 0.2 8.1e-07 29.3 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME81045.1 - 2.5e-07 29.9 0.1 4.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME81045.1 - 3.4e-06 26.1 0.0 5.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EME81045.1 - 4.3e-06 26.0 1.1 6.2e-06 25.5 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME81045.1 - 5.3e-06 25.6 0.2 1.9e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EME81045.1 - 2.4e-05 24.4 1.2 0.00018 21.6 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME81045.1 - 0.00012 20.7 0.2 0.00019 20.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EME81045.1 - 0.00019 20.6 0.0 0.00026 20.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EME81045.1 - 0.00055 18.9 0.3 0.065 12.1 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EME81045.1 - 0.00093 18.8 0.3 0.002 17.7 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EME81045.1 - 0.0012 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME81045.1 - 0.003 16.4 0.4 0.005 15.7 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EME81045.1 - 0.025 14.2 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 EME81046.1 - 9.2e-32 110.1 17.0 9.2e-32 110.1 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM PF00493.18 EME81047.1 - 7.4e-139 462.1 0.0 1e-138 461.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EME81047.1 - 1.4e-32 112.8 27.2 1.4e-32 112.8 18.8 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EME81047.1 - 2.3e-19 70.0 0.0 9.4e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME81047.1 - 2.2e-08 33.5 0.1 2.6e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME81047.1 - 3.3e-06 26.8 0.0 6.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME81047.1 - 0.00048 19.7 0.1 0.002 17.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME81047.1 - 0.0007 19.1 0.1 0.0058 16.1 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain APG9 PF04109.11 EME81048.1 - 2.5e-131 438.0 0.4 3.2e-131 437.6 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 PriCT_1 PF08708.6 EME81048.1 - 0.026 14.3 0.0 3.3 7.5 0.0 3.3 3 1 0 3 3 3 0 Primase C terminal 1 (PriCT-1) PrpF PF04303.8 EME81049.1 - 6e-96 321.4 0.2 7.2e-96 321.1 0.2 1.0 1 0 0 1 1 1 1 PrpF protein SAYSvFN PF10260.4 EME81050.1 - 0.72 9.6 5.7 1.3 8.8 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Peptidase_M56 PF05569.6 EME81050.1 - 2.2 7.1 6.1 3.6 6.4 4.2 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 DEAD PF00270.24 EME81052.1 - 2.3e-48 163.8 0.0 6.6e-46 155.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EME81052.1 - 1.2e-27 95.6 0.0 1.1e-25 89.3 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME81052.1 - 6.7e-06 26.0 0.0 1.9e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EME81052.1 - 0.0024 16.3 0.1 0.22 9.9 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1253) Helicase_RecD PF05127.9 EME81052.1 - 0.0044 16.6 0.5 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Helicase Fungal_trans PF04082.13 EME81053.1 - 0.002 17.0 0.2 0.0036 16.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-DNL PF05180.7 EME81054.1 - 3.3e-25 87.6 1.9 4.1e-25 87.2 1.3 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.1 EME81054.1 - 0.0029 17.2 1.2 0.031 13.9 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EME81054.1 - 0.004 16.7 1.2 0.041 13.4 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Elf1 PF05129.8 EME81054.1 - 0.012 15.2 0.7 0.019 14.6 0.5 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 EME81054.1 - 0.047 13.0 0.7 0.061 12.6 0.5 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger RNHCP PF12647.2 EME81054.1 - 0.057 13.2 2.1 3.5 7.5 0.0 2.0 1 1 1 2 2 2 0 RNHCP domain zf-C3HC4_2 PF13923.1 EME81054.1 - 0.06 13.3 2.1 0.11 12.5 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME81054.1 - 0.1 12.3 4.1 0.16 11.6 2.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 EME81054.1 - 0.1 12.3 0.2 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-trcl PF13451.1 EME81054.1 - 0.21 11.2 3.8 0.2 11.3 1.4 1.9 2 1 0 2 2 2 0 Probable zinc-binding domain Glyco_hydro_20 PF00728.17 EME81055.1 - 4.4e-87 292.4 2.4 5.4e-87 292.2 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EME81055.1 - 3.7e-23 82.5 0.0 1.5e-22 80.6 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EME81055.1 - 3.7e-09 37.1 0.0 2.4e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pyridox_oxidase PF01243.15 EME81056.1 - 5.5e-11 42.3 0.0 1.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EMP70 PF02990.11 EME81057.1 - 2.7e-197 656.3 4.2 3.4e-197 656.0 2.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 EME81057.1 - 0.78 8.9 6.2 0.4 9.8 1.9 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Glyco_hydro_cc PF11790.3 EME81059.1 - 5.4e-57 192.9 0.5 7.9e-57 192.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cullin PF00888.17 EME81060.1 - 2.4e-134 449.0 6.3 3.3e-134 448.6 4.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME81060.1 - 7.6e-26 89.7 0.7 7.6e-26 89.7 0.5 2.3 3 0 0 3 3 3 1 Cullin protein neddylation domain Rrf2 PF02082.15 EME81060.1 - 0.03 14.4 0.0 0.091 12.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_IclR PF09339.5 EME81060.1 - 0.21 11.1 1.4 0.44 10.1 0.3 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain S4 PF01479.20 EME81062.1 - 1.4e-11 43.6 0.0 2.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EME81062.1 - 3.1e-08 33.8 0.1 5.3e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain His_biosynth PF00977.16 EME81063.1 - 6.8e-47 159.6 0.1 4.9e-46 156.8 0.1 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EME81063.1 - 6.1e-29 100.8 0.0 1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EME81063.1 - 1.5e-10 40.9 0.0 1.8e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EME81063.1 - 5.2e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 EME81063.1 - 0.0013 17.6 0.1 0.0024 16.7 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 EME81063.1 - 0.0042 16.5 0.0 0.012 15.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 PhzC-PhzF PF02567.11 EME81065.1 - 9.8e-17 61.0 0.1 1.4e-16 60.5 0.0 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Trp_leader1 PF08055.6 EME81067.1 - 0.71 9.4 3.1 0.87 9.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan leader peptide p450 PF00067.17 EME81068.1 - 2.8e-60 204.1 0.0 3.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 OTU PF02338.14 EME81069.1 - 0.074 13.6 0.1 0.14 12.7 0.0 1.5 1 1 0 1 1 1 0 OTU-like cysteine protease DUF4232 PF14016.1 EME81072.1 - 0.12 11.9 0.1 2.2 7.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4232) Rep_fac-A_C PF08646.5 EME81073.1 - 6.2e-54 181.6 9.6 8.5e-52 174.7 4.7 2.7 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EME81073.1 - 1.6e-22 79.1 0.0 4.1e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EME81073.1 - 9.5e-14 51.0 0.1 3.2e-09 36.5 0.0 4.0 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain Pkinase PF00069.20 EME81074.1 - 1.1e-11 44.4 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EME81074.1 - 1.1e-06 28.5 1.3 1.8e-06 27.8 0.8 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EME81074.1 - 5.5e-05 22.3 0.0 8.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EME81074.1 - 0.00046 19.3 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EME81074.1 - 0.0033 16.7 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EME81074.1 - 0.066 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EME81074.1 - 0.071 12.6 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Arylsulfotran_2 PF14269.1 EME81075.1 - 3.9e-33 114.8 0.2 6.3e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME81075.1 - 1.9e-20 72.8 2.4 2.7e-19 69.0 1.7 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Pyr_redox_3 PF13738.1 EME81076.1 - 8.4e-24 84.7 0.0 1.3e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME81076.1 - 5.3e-15 54.6 0.0 1.2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME81076.1 - 4.9e-10 39.6 0.0 5.4e-07 29.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME81076.1 - 1.8e-09 37.0 0.0 1.1e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME81076.1 - 4.1e-08 33.1 0.0 3.6e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME81076.1 - 9.2e-07 28.0 2.3 0.0028 16.6 0.1 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EME81076.1 - 0.0025 16.9 0.1 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EME81076.1 - 0.0035 16.2 0.0 0.0086 14.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME81076.1 - 0.056 13.8 0.0 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME81076.1 - 0.066 12.2 0.1 0.15 11.1 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EME81076.1 - 0.067 12.3 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EME81076.1 - 0.29 9.9 1.2 0.76 8.6 0.1 2.2 2 1 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EME81076.1 - 1.3 7.8 2.7 1.2 7.8 0.1 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EME81076.1 - 2.5 7.8 6.4 10 5.9 0.0 3.8 5 0 0 5 5 5 0 FAD-NAD(P)-binding Amidase PF01425.16 EME81079.1 - 9.8e-84 281.7 0.0 1.3e-83 281.3 0.0 1.1 1 0 0 1 1 1 1 Amidase FSH1 PF03959.8 EME81080.1 - 7.1e-47 159.5 0.0 8.1e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EME81080.1 - 6.4e-06 26.2 0.0 0.0098 15.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME81080.1 - 0.0025 17.5 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EME81080.1 - 0.052 12.9 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF4099 PF13351.1 EME81081.1 - 0.054 13.4 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4099) DUF4109 PF13397.1 EME81081.1 - 0.097 13.0 1.3 0.19 12.1 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) CHD5 PF04420.9 EME81082.1 - 0.076 12.6 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 CHD5-like protein Pertussis_S1 PF02917.9 EME81082.1 - 0.14 11.7 0.1 0.17 11.4 0.1 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 MFS_1 PF07690.11 EME81084.1 - 1.5e-36 125.8 30.1 1.5e-36 125.8 20.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME81084.1 - 7.4e-05 21.1 8.8 0.00014 20.2 2.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EME81084.1 - 0.00052 18.7 30.9 0.003 16.1 21.5 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF165 PF02592.10 EME81084.1 - 0.0089 16.2 0.2 0.0089 16.2 0.2 2.6 2 1 0 3 3 3 1 Uncharacterized ACR, YhhQ family COG1738 Churchill PF06573.6 EME81085.1 - 0.053 13.5 0.2 0.059 13.3 0.1 1.1 1 0 0 1 1 1 0 Churchill protein Fasciclin PF02469.17 EME81087.1 - 2.1e-40 137.6 2.6 6.5e-25 87.5 0.8 2.1 2 0 0 2 2 2 2 Fasciclin domain PmrD PF11183.3 EME81087.1 - 0.096 12.5 0.2 12 5.8 0.0 2.7 3 0 0 3 3 3 0 Polymyxin resistance protein PmrD Grp1_Fun34_YaaH PF01184.14 EME81088.1 - 6.4e-25 87.6 21.5 8.3e-25 87.3 14.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_4 PF01063.14 EME81089.1 - 3.7e-37 127.9 0.0 4.6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV SH3_2 PF07653.12 EME81089.1 - 0.091 12.2 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain SURF6 PF04935.7 EME81091.1 - 1.2e-47 162.0 44.7 1.4e-47 161.7 31.0 1.0 1 0 0 1 1 1 1 Surfeit locus protein 6 DASH_Spc34 PF08657.5 EME81095.1 - 8.6e-46 156.7 8.1 1.7e-22 80.3 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Uds1 PF15456.1 EME81095.1 - 0.0007 19.5 2.6 0.0019 18.1 1.8 1.7 1 0 0 1 1 1 1 Up-regulated During Septation DASH_Spc19 PF08287.6 EME81095.1 - 0.048 13.2 0.7 0.087 12.4 0.5 1.4 1 0 0 1 1 1 0 Spc19 ISG65-75 PF11727.3 EME81095.1 - 0.063 12.3 1.3 0.081 11.9 0.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DivIVA PF05103.8 EME81095.1 - 0.096 12.7 3.6 0.18 11.8 2.5 1.4 1 0 0 1 1 1 0 DivIVA protein PEARLI-4 PF05278.7 EME81095.1 - 0.19 11.0 2.1 0.26 10.6 1.4 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Prefoldin_2 PF01920.15 EME81095.1 - 0.29 10.9 3.0 0.57 9.9 0.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EME81095.1 - 2.4 7.7 5.0 4.6 6.8 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 EME81095.1 - 4.7 7.7 6.9 5 7.6 1.7 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PCI PF01399.22 EME81096.1 - 5.8e-20 71.5 0.3 1.7e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EME81096.1 - 7.8e-19 67.8 0.7 1.8e-18 66.6 0.5 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 EME81096.1 - 0.0043 16.8 0.1 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 ABA_WDS PF02496.11 EME81097.1 - 0.0018 18.3 2.1 0.0035 17.4 1.5 1.4 1 0 0 1 1 1 1 ABA/WDS induced protein WW PF00397.21 EME81097.1 - 0.03 14.1 0.3 0.078 12.8 0.2 1.8 1 0 0 1 1 1 0 WW domain SAGA-Tad1 PF12767.2 EME81098.1 - 6.2e-36 124.3 0.0 8.2e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Vac7 PF12751.2 EME81099.1 - 1.8e-107 359.6 6.6 1.8e-107 359.6 4.6 1.8 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 Peptidase_M3 PF01432.15 EME81100.1 - 7.4e-112 374.6 4.6 1e-111 374.2 3.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 Nuc-transf PF10127.4 EME81100.1 - 0.0095 15.3 0.4 0.026 13.8 0.3 1.7 1 0 0 1 1 1 1 Predicted nucleotidyltransferase CN_hydrolase PF00795.17 EME81103.1 - 1.2e-29 103.0 0.0 2e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HEM4 PF02602.10 EME81104.1 - 4.6e-33 114.3 0.0 4.8e-32 111.0 0.0 2.0 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD HTH_33 PF13592.1 EME81104.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Evr1_Alr PF04777.8 EME81105.1 - 4.9e-28 96.8 3.1 4.9e-28 96.8 2.2 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Strep_SA_rep PF06696.6 EME81106.1 - 0.048 13.4 3.0 0.61 9.9 0.1 2.4 2 0 0 2 2 2 0 Streptococcal surface antigen repeat LTXXQ PF07813.7 EME81106.1 - 0.15 12.5 4.0 0.29 11.6 1.3 2.2 1 1 1 2 2 2 0 LTXXQ motif family protein SHMT PF00464.14 EME81107.1 - 6.3e-200 663.6 0.0 7.4e-200 663.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase S-AdoMet_synt_C PF02773.11 EME81108.1 - 1.4e-72 241.8 0.2 2.6e-72 241.0 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EME81108.1 - 6.5e-44 148.7 0.0 1.4e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EME81108.1 - 1.6e-43 146.9 0.7 7.2e-43 144.8 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain 6PGD PF00393.14 EME81109.1 - 1.8e-133 444.2 0.0 2.4e-133 443.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EME81109.1 - 2.3e-49 167.3 0.1 4.5e-49 166.4 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME81109.1 - 0.002 18.1 0.5 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MAD PF05557.8 EME81110.1 - 4.3e-44 150.7 75.5 6.5e-44 150.1 52.3 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Rab5-bind PF09311.6 EME81110.1 - 0.003 17.4 31.0 0.003 17.4 21.5 5.8 2 2 3 5 5 5 2 Rabaptin-like protein Reo_sigmaC PF04582.7 EME81110.1 - 0.0081 15.3 29.4 0.22 10.6 0.1 4.2 3 1 1 4 4 4 3 Reovirus sigma C capsid protein gpW PF02831.10 EME81110.1 - 2.4 7.7 7.9 11 5.6 0.1 4.5 4 0 0 4 4 4 0 gpW INCA1 PF15142.1 EME81110.1 - 9.9 5.9 13.7 1 9.0 0.2 3.3 3 1 0 3 3 3 0 INCA1 ABC_ATPase PF09818.4 EME81112.1 - 1.9e-161 537.6 0.0 2.4e-161 537.2 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 EME81112.1 - 0.005 17.1 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Band_7 PF01145.20 EME81113.1 - 4.3e-28 98.4 1.9 6.6e-28 97.8 1.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Dak1_2 PF13684.1 EME81113.1 - 0.051 12.5 1.9 0.078 11.8 1.3 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Band_7_1 PF13421.1 EME81113.1 - 0.091 12.2 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family HET PF06985.6 EME81114.1 - 1.8e-15 57.3 0.0 4e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HrpA_pilin PF09589.5 EME81116.1 - 0.056 13.8 0.2 0.075 13.4 0.1 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein DUF4191 PF13829.1 EME81117.1 - 0.26 10.3 2.3 0.16 11.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4239 PF14023.1 EME81117.1 - 2.9 7.2 9.8 8.5 5.6 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) MutS_V PF00488.16 EME81118.1 - 4.6e-95 317.5 0.1 7.3e-95 316.8 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME81118.1 - 1.5e-38 132.6 0.6 4.5e-38 131.0 0.4 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EME81118.1 - 1.7e-20 73.4 0.0 1.7e-20 73.4 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EME81118.1 - 3.7e-17 62.2 0.8 3.7e-17 62.2 0.6 2.4 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 EME81118.1 - 1.2e-15 57.5 0.0 1.5e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 MutS domain I Sua5_yciO_yrdC PF01300.13 EME81120.1 - 5.2e-53 178.9 0.0 7.4e-53 178.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EME81120.1 - 9e-27 93.6 0.0 1.4e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Peptidase_C15 PF01470.12 EME81121.1 - 7.9e-12 45.4 0.0 1.1e-10 41.7 0.0 2.0 1 1 0 1 1 1 1 Pyroglutamyl peptidase GMC_oxred_N PF00732.14 EME81122.1 - 1.6e-65 221.2 0.0 2.1e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME81122.1 - 6e-39 133.6 0.0 9.9e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME81122.1 - 6.7e-05 21.9 1.3 0.00089 18.2 0.3 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EME81122.1 - 0.00012 21.9 0.7 0.00053 19.9 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME81122.1 - 0.00021 20.2 1.2 0.0012 17.8 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME81122.1 - 0.00059 18.8 0.1 0.00093 18.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EME81122.1 - 0.0058 16.7 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME81122.1 - 0.0065 15.5 0.1 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EME81122.1 - 0.011 14.2 0.1 0.019 13.4 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EME81122.1 - 0.016 15.5 0.1 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME81122.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LRR_6 PF13516.1 EME81123.1 - 7e-05 22.5 0.0 0.58 10.3 0.0 4.6 5 0 0 5 5 5 2 Leucine Rich repeat F-box-like PF12937.2 EME81123.1 - 0.00017 21.2 0.2 0.0004 20.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EME81123.1 - 0.079 12.6 0.0 4.4 7.0 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EME81123.1 - 0.086 12.5 0.6 0.28 10.8 0.1 2.1 2 0 0 2 2 2 0 F-box domain RRM_1 PF00076.17 EME81125.1 - 6.7e-18 64.0 0.7 1.6e-17 62.8 0.2 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME81125.1 - 1.5e-11 44.1 0.0 2.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME81125.1 - 1.6e-07 31.0 0.1 2.4e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.17 EME81126.1 - 2e-09 37.6 0.0 8.5e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EME81126.1 - 6.2e-09 35.7 0.2 1.7e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Cupin-like domain PHD PF00628.24 EME81126.1 - 1.2e-07 31.2 5.9 1.2e-07 31.2 4.1 2.5 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EME81126.1 - 0.0023 17.2 2.7 0.0023 17.2 1.9 2.4 2 0 0 2 2 2 1 PHD-finger C1_4 PF07975.7 EME81126.1 - 0.01 15.8 1.6 0.01 15.8 1.1 2.5 3 0 0 3 3 3 0 TFIIH C1-like domain Dickkopf_N PF04706.7 EME81126.1 - 1.4 9.1 15.8 0.46 10.6 1.7 3.1 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region zf-CW PF07496.10 EME81126.1 - 4.6 7.0 14.8 0.072 12.8 1.6 2.9 3 0 0 3 3 3 0 CW-type Zinc Finger Zn_clus PF00172.13 EME81126.1 - 5.7 6.9 29.6 1.7 8.6 5.7 3.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_efflux PF01545.16 EME81128.1 - 7.6e-38 130.2 4.5 8.3e-37 126.7 3.1 2.0 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 EME81128.1 - 0.00012 21.1 36.0 0.0013 17.8 20.1 2.5 1 1 2 3 3 3 3 ZIP Zinc transporter SelP_N PF04592.9 EME81129.1 - 0.76 9.1 12.0 1.3 8.3 8.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EME81129.1 - 1.9 7.3 16.3 4.8 6.0 11.3 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_trans_1_4 PF13692.1 EME81130.1 - 1.8e-22 79.9 0.0 4.1e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME81130.1 - 0.00039 20.5 0.4 0.00072 19.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EME81130.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 GFO_IDH_MocA PF01408.17 EME81132.1 - 2.8e-27 95.6 0.0 4.4e-26 91.7 0.0 2.6 2 1 1 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EME81132.1 - 0.00076 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EME81132.1 - 0.046 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CRAL_TRIO_2 PF13716.1 EME81132.1 - 0.047 13.5 0.3 1 9.2 0.0 2.3 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain TPR_11 PF13414.1 EME81133.1 - 1.8e-11 43.5 13.2 9.2e-08 31.6 3.7 2.9 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EME81133.1 - 4.5e-08 32.4 7.0 0.17 11.8 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EME81133.1 - 6.9e-08 31.7 6.4 0.0077 15.8 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME81133.1 - 6.6e-05 23.4 4.1 0.0017 18.9 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME81133.1 - 0.0019 18.5 2.8 0.0055 17.0 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EME81133.1 - 0.0022 18.0 3.8 0.0049 16.9 2.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Calpain_inhib PF00748.14 EME81133.1 - 0.021 15.1 1.4 0.021 15.1 1.0 2.0 2 0 0 2 2 2 0 Calpain inhibitor TPR_14 PF13428.1 EME81133.1 - 0.022 15.3 4.5 0.93 10.3 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME81133.1 - 0.031 14.4 0.5 0.12 12.6 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 EME81133.1 - 0.1 12.4 0.2 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Mcp5_PH PF12814.2 EME81137.1 - 3.3e-42 143.3 0.0 6.3e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EME81137.1 - 0.0084 15.8 15.2 0.012 15.3 2.8 2.3 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 EME81137.1 - 0.035 11.4 15.1 0.046 11.0 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 EME81137.1 - 0.41 10.5 18.1 0.53 10.1 5.2 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EME81137.1 - 7.7 5.4 13.5 13 4.6 9.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PDZ_1 PF12812.2 EME81140.1 - 1.9e-48 162.2 0.0 4.1e-31 106.6 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EME81140.1 - 7e-16 57.9 0.7 1.4e-06 28.0 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EME81140.1 - 1.7e-12 47.4 0.0 1.8e-11 44.0 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EME81140.1 - 5.3e-12 45.7 0.0 1.5e-05 25.1 0.0 3.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EME81140.1 - 2.8e-05 23.8 0.0 6.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EME81140.1 - 0.0048 16.6 0.6 4.7 7.0 0.1 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EME81140.1 - 0.19 11.1 0.9 0.39 10.1 0.1 1.9 3 0 0 3 3 3 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EME81140.1 - 0.23 10.7 0.2 0.42 9.8 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) ORC6 PF05460.8 EME81141.1 - 0.012 14.6 3.8 0.013 14.5 2.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Siah-Interact_N PF09032.6 EME81141.1 - 8.6 6.4 7.5 0.96 9.5 0.3 2.3 1 1 2 3 3 3 0 Siah interacting protein, N terminal Mito_carr PF00153.22 EME81143.1 - 2.4e-77 254.7 4.0 7.7e-26 89.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like_2 PF13013.1 EME81144.1 - 0.089 12.5 0.2 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain MIP PF00230.15 EME81145.1 - 3.9e-32 111.5 7.2 5.2e-32 111.1 5.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein PC4 PF02229.11 EME81146.1 - 5.5e-16 57.5 0.1 1.3e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) SpoIIIAH PF12685.2 EME81146.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.4 2 1 1 3 3 3 0 SpoIIIAH-like protein PGA2 PF07543.7 EME81146.1 - 9 6.0 11.3 7 6.4 4.5 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 adh_short PF00106.20 EME81147.1 - 4.3e-25 88.5 0.3 8.1e-25 87.6 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME81147.1 - 7e-14 52.1 0.0 8.1e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME81147.1 - 2.6e-11 43.5 0.1 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME81147.1 - 0.068 12.5 0.2 0.28 10.5 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AAA PF00004.24 EME81148.1 - 7.5e-53 178.2 0.0 1.3e-39 135.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EME81148.1 - 5.8e-11 42.1 0.0 1.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EME81148.1 - 2.9e-10 40.4 0.2 0.00075 19.6 0.0 4.5 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EME81148.1 - 8.6e-10 38.8 1.8 0.00048 20.1 0.0 3.5 3 1 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EME81148.1 - 5.7e-09 35.1 0.0 0.00084 18.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EME81148.1 - 6.3e-08 32.5 0.0 0.0025 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EME81148.1 - 7.9e-08 31.7 0.1 0.0045 16.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME81148.1 - 9.1e-08 31.9 0.1 0.0015 18.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 EME81148.1 - 9.4e-08 31.5 0.3 3.3e-06 26.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 EME81148.1 - 9.5e-08 32.8 0.0 0.0028 18.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EME81148.1 - 1.6e-07 31.3 0.0 7.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EME81148.1 - 3e-07 30.0 0.4 0.029 13.8 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein RuvB_N PF05496.7 EME81148.1 - 3.4e-07 29.5 0.9 0.034 13.2 0.0 3.4 4 1 1 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME81148.1 - 5.5e-07 29.2 1.8 0.017 14.8 0.1 2.8 3 0 0 3 3 2 2 Part of AAA domain Sigma54_activat PF00158.21 EME81148.1 - 2.5e-06 27.0 0.3 0.064 12.7 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.1 EME81148.1 - 4e-06 27.1 0.2 0.0048 17.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EME81148.1 - 4.4e-06 26.4 3.2 0.062 12.9 0.1 3.9 2 2 1 3 3 3 1 NACHT domain KaiC PF06745.8 EME81148.1 - 4.9e-06 25.8 0.2 0.009 15.1 0.1 2.5 2 0 0 2 2 2 2 KaiC AAA_33 PF13671.1 EME81148.1 - 6.1e-06 26.1 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EME81148.1 - 9.1e-06 25.8 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EME81148.1 - 1e-05 25.8 1.1 0.035 14.3 0.1 2.9 3 0 0 3 3 2 2 ABC transporter PhoH PF02562.11 EME81148.1 - 3e-05 23.3 0.0 0.036 13.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.1 EME81148.1 - 3.4e-05 23.3 0.1 0.48 9.7 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.1 EME81148.1 - 0.0001 21.9 0.2 0.12 11.9 0.1 2.8 3 0 0 3 3 3 1 AAA domain DEAD PF00270.24 EME81148.1 - 0.00016 21.2 1.0 0.22 10.9 0.1 4.2 2 2 1 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EME81148.1 - 0.0002 21.2 0.2 0.061 13.1 0.0 3.0 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EME81148.1 - 0.0002 20.5 0.1 0.6 9.1 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Arch_ATPase PF01637.13 EME81148.1 - 0.00024 20.9 0.5 4.1 7.0 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 EME81148.1 - 0.00068 19.2 0.1 0.71 9.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EME81148.1 - 0.00073 18.4 0.1 0.88 8.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain T2SE PF00437.15 EME81148.1 - 0.00079 18.3 0.0 0.17 10.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 EME81148.1 - 0.001 18.6 0.0 0.43 10.1 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EME81148.1 - 0.0015 18.4 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EME81148.1 - 0.0026 17.3 0.4 0.33 10.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 EME81148.1 - 0.0048 15.9 0.1 0.3 9.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EME81148.1 - 0.0048 16.9 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EME81148.1 - 0.0057 15.5 0.0 0.34 9.7 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 EME81148.1 - 0.0091 15.5 0.1 0.45 10.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EME81148.1 - 0.014 14.8 0.0 0.69 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain IPT PF01745.11 EME81148.1 - 0.017 14.2 0.1 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_11 PF13086.1 EME81148.1 - 0.018 14.6 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EME81148.1 - 0.039 14.2 1.3 2.5 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EME81148.1 - 0.04 13.4 0.0 11 5.3 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EME81148.1 - 0.075 12.6 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EME81148.1 - 0.1 11.8 0.1 0.41 9.8 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TrwB_AAD_bind PF10412.4 EME81148.1 - 0.21 10.1 1.5 3.7 6.0 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ATG16 PF08614.6 EME81150.1 - 2.3e-05 24.3 14.3 2.3e-05 24.3 9.9 4.9 1 1 3 5 5 5 2 Autophagy protein 16 (ATG16) WXG100 PF06013.7 EME81150.1 - 0.028 14.4 0.2 0.028 14.4 0.1 4.6 5 1 0 5 5 5 0 Proteins of 100 residues with WXG Reo_sigmaC PF04582.7 EME81150.1 - 0.18 10.9 12.0 0.56 9.3 0.7 3.2 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 EME81150.1 - 4.6 7.2 15.1 0.79 9.6 0.3 4.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat LMBR1 PF04791.11 EME81151.1 - 1 7.8 6.3 0.46 9.0 0.1 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein NYD-SP28_assoc PF14775.1 EME81151.1 - 7.1 6.4 9.1 1.1 8.9 1.3 3.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain WD40 PF00400.27 EME81152.1 - 2.1e-07 30.5 3.1 0.44 10.5 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nab2 PF11517.3 EME81153.1 - 0.025 14.6 0.1 0.03 14.4 0.1 1.4 1 1 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) HEAT PF02985.17 EME81153.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat Nucleos_tra2_C PF07662.8 EME81154.1 - 2.2e-67 226.5 3.2 2.2e-67 226.5 2.2 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EME81154.1 - 1.8e-23 82.6 3.1 1.8e-23 82.6 2.2 3.4 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus zf-CCCH_2 PF14608.1 EME81155.1 - 7.8e-10 38.3 18.9 1.4e-07 31.1 6.5 5.2 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type 3HCDH_N PF02737.13 EME81156.1 - 5.7e-40 136.8 0.0 1.2e-39 135.8 0.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EME81156.1 - 6.7e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.19 EME81156.1 - 0.00014 20.8 0.1 0.00029 19.8 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EME81156.1 - 0.00027 20.7 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 EME81156.1 - 0.0012 18.7 0.1 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ldh_1_N PF00056.18 EME81156.1 - 0.0024 17.6 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EME81156.1 - 0.0085 15.2 0.0 0.067 12.3 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EME81156.1 - 0.019 14.3 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EME81156.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME81156.1 - 0.023 14.0 0.0 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EME81156.1 - 0.044 14.2 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EME81156.1 - 0.047 13.2 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EME81156.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DNA_pol_phi PF04931.8 EME81157.1 - 1.6e-45 155.1 19.4 2.9e-45 154.3 13.4 1.4 1 1 0 1 1 1 1 DNA polymerase phi Sugar_tr PF00083.19 EME81158.1 - 4.6e-80 269.4 16.2 1e-76 258.3 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME81158.1 - 3.8e-20 71.9 22.1 8.9e-20 70.6 15.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ELFV_dehydrog PF00208.16 EME81159.1 - 1.2e-60 205.1 0.0 2.4e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EME81159.1 - 4.1e-17 61.0 0.1 1.1e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EME81159.1 - 0.046 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glyco_hydro_16 PF00722.16 EME81160.1 - 1.4e-42 145.0 5.2 2.5e-42 144.2 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_2 PF02210.19 EME81160.1 - 0.0054 16.7 0.1 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain DUF1080 PF06439.6 EME81160.1 - 0.0055 16.6 0.3 0.0096 15.8 0.2 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Big_2 PF02368.13 EME81160.1 - 5.4 6.9 18.3 0.54 10.1 0.1 4.2 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 2) Aldedh PF00171.17 EME81161.1 - 8.3e-11 40.8 1.4 4.5e-10 38.4 0.3 2.3 2 1 0 2 2 2 1 Aldehyde dehydrogenase family BTB PF00651.26 EME81162.1 - 7.3e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TPR_17 PF13431.1 EME81162.1 - 0.025 14.7 0.0 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.15 EME81163.1 - 5.2e-15 55.3 0.7 2.5e-14 53.1 0.5 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribophorin_I PF04597.9 EME81164.1 - 3.4e-150 500.3 1.0 3.9e-150 500.1 0.7 1.0 1 0 0 1 1 1 1 Ribophorin I DRIM PF07539.7 EME81165.1 - 7.8e-42 142.0 0.0 1e-40 138.3 0.0 3.2 2 0 0 2 2 2 1 Down-regulated in metastasis CLASP_N PF12348.3 EME81165.1 - 9.4e-05 21.8 4.6 0.018 14.3 0.0 5.2 5 1 1 6 6 6 2 CLASP N terminal Arm PF00514.18 EME81165.1 - 0.25 11.2 5.0 6.8 6.6 0.1 4.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CwfJ_C_1 PF04677.10 EME81166.1 - 2.8e-21 75.4 0.0 7.9e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EME81166.1 - 3.3e-18 65.9 1.4 6.6e-18 65.0 0.9 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF1627 PF07789.7 EME81166.1 - 0.018 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Innate_immun PF12782.2 EME81166.1 - 0.021 14.0 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family HIT PF01230.18 EME81166.1 - 0.039 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 HIT domain EF-hand_7 PF13499.1 EME81167.1 - 3.3e-27 94.3 11.5 1e-12 47.9 0.4 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EME81167.1 - 9.6e-24 80.8 12.3 4.7e-08 31.7 0.1 4.9 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EME81167.1 - 6.4e-23 78.5 3.3 5.4e-06 25.8 0.1 5.2 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EME81167.1 - 3.1e-16 57.8 14.9 3.6e-05 22.9 0.0 5.1 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EME81167.1 - 7.4e-14 51.1 12.2 4.5e-05 22.9 0.8 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EME81167.1 - 5.2e-08 32.5 7.3 0.0031 17.2 0.1 3.8 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EME81167.1 - 0.0002 21.3 1.5 0.44 10.5 0.1 3.4 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EME81167.1 - 0.00092 19.0 0.3 0.024 14.5 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EME81167.1 - 0.0044 16.6 2.0 1.1 9.0 0.0 4.0 4 1 0 4 4 4 1 EF hand Toprim PF01751.17 EME81167.1 - 0.011 15.6 0.0 1.5 8.8 0.0 2.3 1 1 0 1 1 1 0 Toprim domain EF-hand_2 PF09068.6 EME81167.1 - 0.032 14.3 0.1 4.7 7.2 0.0 3.1 3 1 1 4 4 4 0 EF hand DUF1679 PF07914.6 EME81167.1 - 0.038 12.6 0.6 3.7 6.0 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) COG6 PF06419.6 EME81168.1 - 4.4e-198 659.3 6.0 5e-198 659.1 4.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EME81168.1 - 8.9e-05 22.3 0.1 0.00055 19.8 0.1 2.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_I PF06008.9 EME81168.1 - 0.074 12.3 4.7 0.92 8.7 0.2 3.1 3 0 0 3 3 3 0 Laminin Domain I DUF4225 PF13988.1 EME81168.1 - 0.22 10.9 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Oxidored_FMN PF00724.15 EME81169.1 - 4.7e-71 239.5 0.0 6.1e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UQ_con PF00179.21 EME81171.1 - 2.2e-51 173.0 0.0 2.4e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME81171.1 - 6.9e-05 22.6 0.0 8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME81171.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EME81171.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_1 PF00441.19 EME81172.1 - 6.3e-25 88.0 0.3 1.1e-24 87.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME81172.1 - 1.7e-22 80.1 0.5 3.3e-22 79.1 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EME81172.1 - 5.7e-16 57.7 0.0 1.5e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EME81172.1 - 3.7e-08 33.6 0.1 6.6e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_N PF00752.12 EME81173.1 - 4.1e-30 104.0 0.0 1.3e-29 102.4 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EME81173.1 - 5.4e-30 103.3 0.9 1.2e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EME81173.1 - 3.3e-06 27.2 1.1 1.2e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 EME81173.1 - 0.043 12.5 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein HXXSHH PF07586.6 EME81173.1 - 0.059 12.2 4.5 0.093 11.6 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Fungal_trans PF04082.13 EME81174.1 - 1.9e-06 26.9 0.0 3.2e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81174.1 - 0.014 15.2 9.8 0.025 14.4 6.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME81175.1 - 2.4e-21 75.8 58.7 5.8e-21 74.5 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MTS PF05175.9 EME81176.1 - 0.092 12.1 0.0 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EME81176.1 - 0.092 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.16 EME81177.1 - 2.3e-27 95.4 0.0 3.6e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EME81177.1 - 0.0026 17.8 0.0 0.0074 16.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1817 PF08847.6 EME81177.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) HET PF06985.6 EME81178.1 - 3.5e-32 111.4 3.4 4.8e-32 111.0 2.4 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ThiS-like PF14453.1 EME81178.1 - 0.1 12.4 0.1 26 4.7 0.0 2.9 3 0 0 3 3 3 0 ThiS-like ubiquitin Glyco_hydro_28 PF00295.12 EME81179.1 - 2.6e-35 121.9 5.3 4.3e-35 121.2 3.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EME81179.1 - 1.8 8.2 17.8 0.023 14.4 5.7 2.3 1 1 1 2 2 2 0 Right handed beta helix region PTR2 PF00854.16 EME81180.1 - 7.1e-56 189.5 9.4 9.9e-56 189.1 6.5 1.2 1 0 0 1 1 1 1 POT family IncA PF04156.9 EME81180.1 - 1.1 8.8 6.5 9.4 5.7 2.4 2.4 2 0 0 2 2 2 0 IncA protein DUF1469 PF07332.6 EME81180.1 - 4.7 6.9 14.0 1.2 8.8 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) PXA PF02194.10 EME81183.1 - 4.5e-31 107.8 0.0 9.7e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EME81183.1 - 2.6e-19 69.3 0.4 4.2e-18 65.4 0.0 2.9 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EME81183.1 - 3.9e-07 29.8 0.0 6.5e-06 25.9 0.0 2.7 2 0 0 2 2 2 1 PX domain tRNA-synt_1b PF00579.20 EME81184.1 - 2.8e-55 187.5 0.0 3.9e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HGD-D PF06050.8 EME81185.1 - 0.0033 16.3 0.0 0.0045 15.8 0.0 1.2 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component zf-MYND PF01753.13 EME81186.1 - 4.8e-09 35.9 18.8 8.2e-09 35.1 13.0 1.4 1 0 0 1 1 1 1 MYND finger Glyco_hydro_76 PF03663.9 EME81187.1 - 3.9e-27 95.6 16.3 7.8e-20 71.5 1.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 BRCT PF00533.21 EME81189.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EME81189.1 - 0.0094 15.7 0.1 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain MPLKIP PF15502.1 EME81191.1 - 0.0067 17.1 0.6 0.012 16.3 0.4 1.7 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein Abhydrolase_6 PF12697.2 EME81192.1 - 7.9e-15 55.3 0.2 2.2e-14 53.9 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME81192.1 - 1.2e-12 47.8 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EME81192.1 - 3.5e-12 45.6 0.0 5.1e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.15 EME81192.1 - 8.5e-08 31.9 0.1 8.7e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EME81192.1 - 0.00097 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EME81192.1 - 0.0022 17.5 0.2 0.074 12.5 0.0 2.7 2 1 0 3 3 3 1 alpha/beta hydrolase fold MIT PF04212.13 EME81192.1 - 0.018 14.9 0.5 0.032 14.1 0.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain BAAT_C PF08840.6 EME81192.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1771 PF08590.5 EME81192.1 - 1.6 8.8 6.5 0.37 10.8 1.9 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) AD PF09793.4 EME81195.1 - 4.7e-18 64.8 1.2 7.2e-18 64.2 0.4 1.6 1 1 1 2 2 2 1 Anticodon-binding domain Aconitase PF00330.15 EME81195.1 - 0.06 11.8 0.0 1 7.7 0.0 2.0 1 1 1 2 2 2 0 Aconitase family (aconitate hydratase) Fungal_trans PF04082.13 EME81196.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2H-phosphodiest PF08975.5 EME81196.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Kinesin PF00225.18 EME81198.1 - 5.1e-86 288.4 0.8 7.7e-86 287.8 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EME81198.1 - 7.5e-06 25.3 0.2 0.0028 17.2 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EME81198.1 - 0.00026 21.0 0.1 0.0009 19.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.2 EME81198.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Fungal_trans PF04082.13 EME81199.1 - 2.8e-09 36.2 1.4 4.8e-08 32.2 0.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81199.1 - 1.2e-07 31.4 9.8 2.4e-07 30.5 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME81200.1 - 1.3e-14 53.6 15.2 1.3e-14 53.6 10.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Myco_arth_vir_N PF09610.5 EME81200.1 - 0.04 13.8 0.6 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF754 PF05449.6 EME81200.1 - 0.058 13.4 1.1 3.5 7.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF754) GatB_N PF02934.10 EME81201.1 - 3.2e-95 318.3 0.0 4.5e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EME81201.1 - 9.6e-19 67.5 0.8 2.7e-18 66.1 0.4 1.8 2 0 0 2 2 2 1 GatB domain DUF2067 PF09840.4 EME81201.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) IBR PF01485.16 EME81202.1 - 3.3e-06 26.8 7.3 3.3e-06 26.8 5.1 3.4 3 1 0 3 3 3 2 IBR domain zf-B_box PF00643.19 EME81202.1 - 0.031 14.1 8.0 0.031 14.1 5.6 3.9 3 2 1 4 4 4 0 B-box zinc finger zf-RING_2 PF13639.1 EME81202.1 - 0.036 13.9 5.1 0.036 13.9 3.5 3.3 3 1 0 3 3 3 0 Ring finger domain zf-C3HC4_4 PF15227.1 EME81202.1 - 1.4 8.8 23.0 1.2 9.0 3.7 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Herpes_U30 PF04523.8 EME81206.1 - 0.098 10.0 0.0 0.13 9.6 0.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 FtsJ PF01728.14 EME81209.1 - 4.3e-11 43.1 0.0 6.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EME81209.1 - 0.00022 21.7 0.0 0.0016 19.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME81209.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 EME81209.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 NOL1/NOP2/sun family Tyrosinase PF00264.15 EME81211.1 - 1.2e-53 182.6 0.4 2.9e-53 181.3 0.2 1.7 1 0 0 1 1 1 1 Common central domain of tyrosinase Aldo_ket_red PF00248.16 EME81212.1 - 1.9e-56 191.0 0.0 2e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_Mu_2 PF09039.6 EME81212.1 - 0.088 12.5 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain Apc3 PF12895.2 EME81213.1 - 0.00034 20.6 1.5 0.00062 19.8 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EME81213.1 - 0.31 11.0 4.5 0.64 10.0 2.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EME81215.1 - 3.9e-13 49.8 0.1 4.8e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME81215.1 - 4.2e-09 36.3 0.1 7.8e-09 35.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME81215.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EME81215.1 - 0.043 13.3 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lactamase_B PF00753.22 EME81216.1 - 1.5e-10 41.0 1.1 1.9e-10 40.7 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME81216.1 - 1.4e-06 28.0 0.4 2.1e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Metallothio_PEC PF02068.11 EME81216.1 - 0.081 13.2 0.3 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 Plant PEC family metallothionein dCMP_cyt_deam_1 PF00383.17 EME81218.1 - 7.8e-24 83.2 2.0 1.2e-23 82.6 1.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RabGAP-TBC PF00566.13 EME81219.1 - 9.6e-49 165.7 0.0 1.5e-46 158.6 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.17 EME81220.1 - 1.1e-36 124.2 0.3 1.3e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME81220.1 - 2.6e-27 94.6 0.1 2.1e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME81220.1 - 6.8e-12 45.0 0.0 3.6e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME81220.1 - 0.013 15.3 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 EME81220.1 - 0.1 12.4 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CinA PF02464.12 EME81221.1 - 1.4e-32 112.3 0.0 1.5e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein Fungal_trans PF04082.13 EME81222.1 - 8.4e-05 21.5 0.1 0.00016 20.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Serglycin PF04360.7 EME81223.1 - 0.28 10.9 7.9 0.52 10.0 5.5 1.4 1 0 0 1 1 1 0 Serglycin Perilipin PF03036.11 EME81224.1 - 0.019 13.8 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Perilipin family NAD_binding_8 PF13450.1 EME81225.1 - 1.2e-10 41.2 0.1 6e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME81225.1 - 7.5e-08 31.8 0.0 2.6e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EME81225.1 - 1.6e-05 25.0 0.2 4.9e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME81225.1 - 0.0029 16.7 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME81225.1 - 0.0047 16.8 0.0 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME81225.1 - 0.0086 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME81225.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EME81225.1 - 0.035 14.1 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 EME81225.1 - 0.052 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EME81225.1 - 0.062 12.1 0.3 0.36 9.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TPT PF03151.11 EME81226.1 - 7e-28 97.2 9.7 7e-28 97.2 6.7 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EME81226.1 - 2.6e-07 29.8 17.8 3.8e-06 26.0 12.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME81226.1 - 0.0074 16.3 13.0 0.0074 16.3 9.0 2.7 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EME81226.1 - 0.032 13.0 9.4 0.16 10.7 6.5 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) Rhodanese PF00581.15 EME81228.1 - 3.6e-11 43.4 0.0 7.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_4 PF01565.18 EME81229.1 - 1.8e-10 40.4 0.0 4.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.9 EME81229.1 - 2.6e-09 37.0 3.7 1.4e-08 34.6 2.5 1.9 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Chol_subst-bind PF09129.6 EME81229.1 - 0.45 9.5 7.0 0.83 8.7 0.4 2.7 1 1 2 3 3 3 0 Cholesterol oxidase, substrate-binding Mago-bind PF09282.5 EME81230.1 - 0.15 11.6 0.4 0.31 10.6 0.3 1.5 1 0 0 1 1 1 0 Mago binding FAD_binding_3 PF01494.14 EME81231.1 - 1.5e-12 47.2 0.0 1.5e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Methyltransf_23 PF13489.1 EME81232.1 - 5.1e-25 88.0 0.1 1.2e-24 86.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME81232.1 - 8.8e-09 35.1 0.0 5.1e-07 29.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME81232.1 - 2.8e-08 34.3 0.0 7.4e-07 29.7 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME81232.1 - 3.3e-08 33.9 0.0 7.7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME81232.1 - 3.9e-08 33.6 0.0 1.2e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME81232.1 - 0.00061 18.9 0.0 0.66 9.0 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EME81232.1 - 0.00079 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME81232.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME81232.1 - 0.0095 15.9 0.1 0.043 13.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME81232.1 - 0.012 15.9 0.0 0.12 12.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EME81232.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EME81232.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 EME81232.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Tyrosinase PF00264.15 EME81233.1 - 2.2e-44 152.2 4.3 3.8e-44 151.5 3.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Amidohydro_1 PF01979.15 EME81234.1 - 4.7e-23 82.3 0.4 8.9e-13 48.5 0.1 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EME81234.1 - 2.5e-14 53.9 0.0 1.1e-13 51.8 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EME81234.1 - 5.6e-09 35.6 0.1 1.1e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME81234.1 - 5.8e-07 29.0 0.0 0.0012 18.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 EME81234.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase Rft-1 PF04506.8 EME81236.1 - 2.9e-78 263.5 11.9 1.7e-76 257.7 8.2 2.6 1 1 0 1 1 1 1 Rft protein WD40 PF00400.27 EME81237.1 - 7.2e-25 85.9 15.8 1e-08 34.7 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Cupin_2 PF07883.6 EME81239.1 - 1.8e-06 27.3 0.0 5e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_6 PF12852.2 EME81239.1 - 0.0015 18.2 0.3 0.011 15.3 0.1 2.1 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 EME81239.1 - 0.0036 17.0 0.2 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain KorB_C PF06613.6 EME81239.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain FAD_binding_4 PF01565.18 EME81240.1 - 5.4e-18 64.8 2.3 1.1e-17 63.7 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME81240.1 - 1.4e-10 40.8 0.1 3.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like adh_short_C2 PF13561.1 EME81241.1 - 8.4e-29 101.0 0.2 1e-28 100.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME81241.1 - 1.4e-25 90.1 0.4 1.7e-25 89.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81241.1 - 4.7e-14 52.4 0.1 7e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 KR domain SAM_adeno_trans PF01887.11 EME81241.1 - 0.00069 18.7 0.1 0.00092 18.3 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase Epimerase PF01370.16 EME81241.1 - 0.0041 16.6 0.3 0.009 15.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family S4 PF01479.20 EME81241.1 - 0.037 13.4 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 S4 domain DUF2280 PF10045.4 EME81241.1 - 0.076 12.9 0.1 7.8 6.4 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) NAD_binding_10 PF13460.1 EME81241.1 - 0.091 12.7 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding p450 PF00067.17 EME81244.1 - 1.4e-31 109.5 0.0 1.9e-21 76.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 RPA_interact_N PF14766.1 EME81244.1 - 0.013 14.9 0.7 0.013 14.9 0.5 2.0 2 0 0 2 2 2 0 Replication protein A interacting N-terminal ADH_zinc_N PF00107.21 EME81245.1 - 1e-20 73.6 0.1 2.1e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME81245.1 - 1.3e-19 69.9 0.1 2.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EME81245.1 - 0.058 12.9 0.2 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF605 PF04652.11 EME81246.1 - 0.12 11.7 2.0 0.13 11.6 1.4 1.2 1 0 0 1 1 1 0 Vta1 like ADH_N PF08240.7 EME81247.1 - 5.7e-24 83.9 3.8 8.9e-24 83.3 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME81247.1 - 2.5e-15 56.1 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME81247.1 - 4.5e-07 30.8 0.0 7.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME81247.1 - 0.002 17.3 0.1 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 EME81247.1 - 0.03 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) MatE PF01554.13 EME81248.1 - 2.2e-37 128.1 31.6 4.5e-26 91.4 4.4 2.4 3 0 0 3 3 3 2 MatE Bacteriocin_IId PF09221.5 EME81248.1 - 0.22 11.4 5.6 0.55 10.1 2.2 2.7 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like AMP-binding PF00501.23 EME81249.1 - 3.2e-76 256.3 0.0 4e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME81249.1 - 7.1e-06 26.8 0.0 1.5e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_transf_8 PF01501.15 EME81250.1 - 1.9e-07 30.6 0.5 3.5e-07 29.8 0.3 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EME81250.1 - 0.033 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Aldo_ket_red PF00248.16 EME81252.1 - 1.3e-62 211.2 0.1 1.4e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_2_C PF02836.12 EME81255.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_M35 PF02102.10 EME81256.1 - 5.3e-91 304.9 8.3 5.8e-91 304.8 5.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EME81256.1 - 8.2e-05 23.1 0.2 0.00015 22.2 0.1 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Chitin_bind_1 PF00187.14 EME81256.1 - 0.028 14.3 3.4 0.068 13.1 2.4 1.6 1 0 0 1 1 1 0 Chitin recognition protein DUF3617 PF12276.3 EME81258.1 - 0.024 14.0 0.2 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) CPSF100_C PF13299.1 EME81259.1 - 1.4e-40 139.0 6.9 2.6e-40 138.2 0.1 2.6 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EME81259.1 - 6.5e-25 87.4 0.0 1.6e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EME81259.1 - 1.1e-05 25.0 0.0 3.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EME81259.1 - 0.00059 19.5 0.9 0.0066 16.1 0.4 2.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily ADH_zinc_N PF00107.21 EME81261.1 - 2e-26 92.0 0.4 3.3e-26 91.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME81261.1 - 3.2e-22 78.3 0.7 6.2e-22 77.4 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.23 EME81262.1 - 1.7e-70 237.5 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME81262.1 - 2.9e-19 69.7 0.3 4.9e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_S27 PF01599.14 EME81262.1 - 0.16 11.7 5.5 4.3 7.2 0.0 4.0 4 0 0 4 4 4 0 Ribosomal protein S27a AIM24 PF01987.12 EME81263.1 - 1.2e-38 132.7 0.0 1.5e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PRP1_N PF06424.7 EME81264.1 - 2.5e-51 173.4 7.5 2.5e-51 173.4 5.2 2.2 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EME81264.1 - 9.1e-25 84.9 29.1 0.00089 19.6 0.1 14.4 4 3 11 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.1 EME81264.1 - 7.5e-21 74.2 9.3 5.1e-05 23.5 0.2 10.4 8 3 2 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME81264.1 - 3.2e-14 52.3 5.5 0.12 12.0 0.0 8.5 7 1 1 8 8 8 3 TPR repeat TPR_16 PF13432.1 EME81264.1 - 2e-13 50.5 18.7 0.0032 18.0 2.4 8.3 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME81264.1 - 8e-12 44.1 2.1 1.5 8.9 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat NARP1 PF12569.3 EME81264.1 - 3.3e-06 26.1 6.6 0.43 9.2 0.0 6.0 5 1 2 7 7 7 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 EME81264.1 - 4.9e-06 25.8 18.1 0.0078 15.3 2.0 5.6 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME81264.1 - 5.4e-06 25.7 0.0 1.8 8.5 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat Suf PF05843.9 EME81264.1 - 0.0005 19.8 8.2 0.18 11.5 0.0 4.8 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_1 PF00515.23 EME81264.1 - 0.002 17.6 0.0 5.5 6.7 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME81264.1 - 0.17 11.8 4.8 3.2 7.7 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME81264.1 - 0.44 11.1 14.7 71 4.1 0.0 8.6 11 0 0 11 11 9 0 Tetratricopeptide repeat PIN PF01850.16 EME81264.1 - 1.5 9.1 12.3 0.27 11.5 0.4 3.9 3 1 0 4 4 4 0 PIN domain Acetyltransf_3 PF13302.1 EME81266.1 - 5.6e-28 97.8 0.0 7.4e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME81266.1 - 0.00026 20.9 0.1 0.00082 19.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME81266.1 - 0.0028 17.7 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cu-oxidase PF00394.17 EME81267.1 - 7.5e-31 107.1 0.0 2.7e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EME81267.1 - 1.9e-20 72.7 0.3 1.9e-20 72.7 0.2 2.7 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME81267.1 - 1.1e-19 70.3 7.3 8.7e-19 67.4 0.5 3.0 2 1 0 2 2 2 2 Multicopper oxidase Pox_VLTF3 PF04947.9 EME81269.1 - 0.027 13.9 0.1 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like WD40 PF00400.27 EME81270.1 - 4.8e-57 187.9 28.6 1e-07 31.5 0.6 11.4 11 0 0 11 11 11 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EME81270.1 - 1.4e-06 28.0 0.1 0.0013 18.5 0.0 4.1 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EME81270.1 - 2e-05 24.6 13.2 0.79 10.0 0.1 6.8 8 0 0 8 8 8 2 PQQ-like domain Hira PF07569.6 EME81270.1 - 0.0024 17.1 0.1 0.0044 16.2 0.1 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.7 EME81270.1 - 0.032 13.9 5.6 6.7 6.4 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EME81270.1 - 0.032 12.3 0.4 0.47 8.5 0.0 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 IKI3 PF04762.7 EME81270.1 - 0.16 9.7 1.3 0.27 9.0 0.0 1.8 2 0 0 2 2 2 0 IKI3 family TFIID_20kDa PF03847.8 EME81272.1 - 9.8e-21 73.8 0.0 1.3e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EME81272.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Polysacc_deac_1 PF01522.16 EME81273.1 - 6.6e-20 70.9 0.0 9.8e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EME81273.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 EME81273.1 - 0.056 11.4 0.0 0.085 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) AA_permease PF00324.16 EME81274.1 - 4.3e-113 378.1 45.8 4.9e-113 378.0 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME81274.1 - 2.4e-37 128.4 46.2 3.2e-37 128.0 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Herpes_UL20 PF04544.7 EME81274.1 - 0.013 15.3 3.3 0.013 15.3 2.3 2.4 2 1 0 2 2 2 0 Herpesvirus egress protein UL20 V_ATPase_I PF01496.14 EME81274.1 - 0.19 9.5 0.5 0.29 8.9 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fungal_trans PF04082.13 EME81276.1 - 2.4e-10 39.7 0.1 4.6e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81276.1 - 0.12 12.3 3.6 0.23 11.3 2.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_108 PF05838.7 EME81276.1 - 0.17 12.0 0.0 0.48 10.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Aldo_ket_red PF00248.16 EME81277.1 - 2.5e-36 124.9 0.0 3.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DMA PF03474.9 EME81277.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif DUF575 PF04746.7 EME81277.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Acylphosphatase PF00708.13 EME81279.1 - 6.1e-22 77.5 0.1 6.5e-22 77.4 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Transposase_23 PF03017.9 EME81279.1 - 0.066 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 TNP1/EN/SPM transposase AOX PF01786.12 EME81280.1 - 1.4e-91 305.5 0.5 1.8e-91 305.1 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase MEF2_binding PF09047.5 EME81280.1 - 4.2 7.0 5.0 9.1 6.0 2.7 2.0 2 0 0 2 2 2 0 MEF2 binding GPI2 PF06432.6 EME81281.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase WSC PF01822.14 EME81283.1 - 0.005 16.7 1.3 0.01 15.7 0.3 1.9 2 0 0 2 2 2 1 WSC domain DUF2357 PF09823.4 EME81283.1 - 0.11 11.6 0.4 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Asp PF00026.18 EME81284.1 - 8.8e-08 31.7 5.7 2.2e-06 27.1 3.9 3.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Sugar_tr PF00083.19 EME81286.1 - 6.5e-05 21.6 0.8 6.5e-05 21.6 0.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ribosomal_L16 PF00252.13 EME81287.1 - 9.6e-32 109.5 0.1 1.2e-31 109.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 EME81288.1 - 6.1e-25 86.5 0.0 6.9e-25 86.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DWNN PF08783.6 EME81289.1 - 1.3e-23 82.6 0.2 2.5e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EME81289.1 - 4.6e-05 22.8 3.9 0.00014 21.2 2.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EME81289.1 - 0.0005 20.0 8.5 0.0005 20.0 5.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.18 EME81289.1 - 0.0025 17.6 5.4 0.0087 15.9 1.0 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.1 EME81289.1 - 0.0033 17.0 6.0 0.0033 17.0 4.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EME81289.1 - 0.029 14.2 3.9 0.072 12.9 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.3 EME81289.1 - 0.1 12.1 3.8 0.22 11.0 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCHC_3 PF13917.1 EME81289.1 - 0.14 11.9 2.9 0.11 12.2 0.3 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_4 PF15227.1 EME81289.1 - 0.63 9.9 7.0 2 8.3 4.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Hid1 PF12722.2 EME81289.1 - 1.4 6.5 6.5 1.8 6.1 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PGM_PMM_I PF02878.11 EME81290.1 - 5.5e-41 139.2 0.1 8.7e-41 138.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EME81290.1 - 3.8e-18 65.7 0.0 9.2e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EME81290.1 - 3.4e-13 49.6 0.0 7.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EME81290.1 - 1e-08 35.0 0.0 8.9e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AA_permease_2 PF13520.1 EME81291.1 - 5.5e-54 183.3 47.1 6.7e-54 183.0 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME81291.1 - 1.8e-20 72.7 40.7 2.5e-20 72.3 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease NmrA PF05368.8 EME81292.1 - 0.0012 18.1 0.0 0.0043 16.3 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Methyltransf_28 PF02636.12 EME81292.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase 2OG-FeII_Oxy_2 PF13532.1 EME81293.1 - 2.6e-34 118.7 0.1 3.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EME81293.1 - 0.0008 19.2 6.9 0.0015 18.3 4.8 1.5 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EME81293.1 - 0.043 14.1 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ist1 PF03398.9 EME81296.1 - 1.1e-63 213.5 4.8 1.4e-63 213.2 3.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF2226 PF09987.4 EME81296.1 - 0.31 10.1 3.8 0.87 8.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) adh_short PF00106.20 EME81297.1 - 6.4e-23 81.4 1.0 1.8e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME81297.1 - 9.7e-11 41.6 0.1 2.4e-10 40.3 0.0 1.7 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EME81297.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME81297.1 - 4.1e-06 26.4 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME81297.1 - 0.026 14.5 0.1 0.046 13.7 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding YjeF_N PF03853.10 EME81297.1 - 0.091 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus SIR2 PF02146.12 EME81298.1 - 2.5e-57 193.4 0.0 4.2e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Sir2 family RNase_E_G PF10150.4 EME81298.1 - 0.039 13.1 0.3 0.058 12.6 0.2 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Meth_synt_2 PF01717.13 EME81299.1 - 0.0054 15.7 0.0 0.021 13.8 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain F-box-like PF12937.2 EME81300.1 - 0.0027 17.4 0.8 0.0062 16.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME81300.1 - 0.0078 15.8 0.3 0.023 14.3 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EME81300.1 - 0.11 12.2 0.1 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain SurE PF01975.12 EME81301.1 - 3.4e-33 114.6 0.1 4.5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Cutinase PF01083.17 EME81302.1 - 4.4e-27 94.9 0.6 4.4e-27 94.9 0.4 2.0 2 0 0 2 2 2 1 Cutinase Prominin PF05478.6 EME81304.1 - 0.0054 14.3 2.5 0.0075 13.8 1.8 1.1 1 0 0 1 1 1 1 Prominin SurA_N PF09312.6 EME81304.1 - 0.11 12.3 5.0 7.3 6.4 0.6 2.9 2 1 1 3 3 3 0 SurA N-terminal domain Hema_stalk PF08720.5 EME81304.1 - 0.13 11.7 0.2 0.9 9.0 0.2 1.9 2 0 0 2 2 2 0 Influenza C hemagglutinin stalk Glyco_hydro_18 PF00704.23 EME81305.1 - 1.2e-50 172.9 0.0 2.8e-50 171.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EME81305.1 - 2.6e-10 40.0 0.1 4.7e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 LysM domain DUF3142 PF11340.3 EME81305.1 - 0.00053 19.6 0.0 0.00092 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Chitin_bind_1 PF00187.14 EME81305.1 - 0.00069 19.5 3.3 0.00069 19.5 2.3 3.3 3 0 0 3 3 3 1 Chitin recognition protein TPR_12 PF13424.1 EME81306.1 - 1.3e-06 28.2 3.4 0.00044 20.1 0.3 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EME81306.1 - 0.0065 16.3 2.2 4.7 7.2 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Amidase PF01425.16 EME81308.1 - 4.5e-22 78.5 0.1 6.3e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 Amidase TPR_12 PF13424.1 EME81309.1 - 7.5e-11 41.8 11.3 0.00019 21.3 0.5 5.4 1 1 5 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 EME81309.1 - 5.2e-10 38.6 0.0 1.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EME81309.1 - 5.7e-05 23.2 0.0 0.00053 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 EME81309.1 - 7.8e-05 22.3 0.3 1.3 9.0 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 EME81309.1 - 0.00011 22.2 0.2 0.00057 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.1 EME81309.1 - 0.0013 18.3 0.2 2 8.1 0.0 3.4 2 1 0 2 2 2 2 TPR repeat KaiC PF06745.8 EME81309.1 - 0.018 14.1 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC TPR_1 PF00515.23 EME81309.1 - 0.018 14.6 0.0 0.8 9.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EME81309.1 - 0.037 13.9 0.1 0.037 13.9 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat NACHT PF05729.7 EME81309.1 - 0.039 13.6 0.0 0.086 12.5 0.0 1.6 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 EME81309.1 - 0.054 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus CorA PF01544.13 EME81310.1 - 2e-10 40.1 3.3 8.5e-10 38.1 2.3 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1003 PF06210.6 EME81310.1 - 0.038 13.9 0.6 0.11 12.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF4581 PF15167.1 EME81310.1 - 0.092 12.6 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4581) PrgI PF12666.2 EME81310.1 - 0.17 12.0 1.6 0.5 10.5 1.1 1.7 1 0 0 1 1 1 0 PrgI family protein Indigoidine_A PF04227.7 EME81311.1 - 1.1e-116 389.1 3.5 1.6e-116 388.6 2.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EME81311.1 - 1.1e-16 60.8 0.0 1.2e-08 34.4 0.0 2.8 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Yippee-Mis18 PF03226.9 EME81312.1 - 1.4e-21 76.3 0.0 2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EME81312.1 - 0.0022 17.8 0.1 0.023 14.5 0.1 2.0 2 0 0 2 2 2 1 C-terminal domain of RIG-I LIM PF00412.17 EME81312.1 - 0.42 10.7 2.5 7.8 6.6 0.1 2.6 2 1 0 2 2 2 0 LIM domain SR-25 PF10500.4 EME81312.1 - 2 7.8 5.1 4.1 6.8 3.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec23_trunk PF04811.10 EME81313.1 - 2.1e-69 233.5 0.0 3.7e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EME81313.1 - 2.3e-24 84.7 0.0 2.4e-23 81.5 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EME81313.1 - 3.5e-18 65.9 0.0 9.4e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EME81313.1 - 1.2e-16 59.9 5.8 2.2e-16 59.1 4.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EME81313.1 - 3e-08 33.2 0.0 6.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-H2C2_2 PF13465.1 EME81316.1 - 0.0021 18.2 0.8 0.0021 18.2 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EME81316.1 - 0.67 10.4 7.0 0.21 12.0 2.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CDC45 PF02724.9 EME81316.1 - 4.7 5.1 5.0 7.1 4.5 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EME81316.1 - 6.8 7.0 8.3 22 5.4 5.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RR_TM4-6 PF06459.7 EME81316.1 - 9.8 5.9 7.2 1.3 8.8 2.0 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF885 PF05960.6 EME81317.1 - 7.9e-47 160.6 2.9 9.5e-47 160.3 2.0 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF3105 PF11303.3 EME81317.1 - 0.05 13.4 0.0 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3105) Transp_cyt_pur PF02133.10 EME81319.1 - 4.3e-12 45.3 0.5 4.6e-12 45.2 0.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TauD PF02668.11 EME81320.1 - 1.7e-38 132.7 0.4 2.5e-38 132.2 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.2 EME81321.1 - 1.9e-28 99.8 0.0 2.5e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME81321.1 - 2.3e-17 63.3 0.1 6.2e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME81321.1 - 5.9e-09 35.8 0.1 8.6e-08 32.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME81321.1 - 0.00035 20.3 0.0 0.0012 18.5 0.0 1.9 1 1 1 2 2 2 1 Putative lysophospholipase Glyco_hydro_72 PF03198.9 EME81322.1 - 1.8e-131 437.8 1.9 2.2e-131 437.5 1.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EME81322.1 - 1e-24 86.8 3.8 2.7e-24 85.4 2.7 1.8 1 0 0 1 1 1 1 X8 domain DUF946 PF06101.6 EME81324.1 - 9.7e-10 37.0 3.4 2.1e-09 35.9 1.4 2.2 2 1 0 2 2 2 1 Plant protein of unknown function (DUF946) Chitin_bind_1 PF00187.14 EME81324.1 - 0.00024 21.0 19.8 0.00024 21.0 13.7 2.0 2 0 0 2 2 2 1 Chitin recognition protein TFIIIC_sub6 PF10419.4 EME81326.1 - 2.1e-07 30.3 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit F-box PF00646.28 EME81327.1 - 3e-05 23.5 0.5 8.8e-05 22.0 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME81327.1 - 3.1e-05 23.6 0.4 0.0001 21.9 0.3 1.9 1 0 0 1 1 1 1 F-box-like E1_DerP2_DerF2 PF02221.10 EME81328.1 - 0.00045 20.4 0.1 0.0012 19.1 0.0 1.7 2 1 0 2 2 2 1 ML domain Reo_sigmaC PF04582.7 EME81330.1 - 5.8 5.9 14.8 0.85 8.7 1.0 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein WD40 PF00400.27 EME81331.1 - 8.2e-41 136.4 11.2 2.6e-11 42.9 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.9 EME81331.1 - 3.4e-32 110.3 15.5 5e-32 109.7 10.8 1.2 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EME81331.1 - 6.8e-06 25.9 0.3 2e-05 24.4 0.0 1.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EME81331.1 - 0.0059 14.7 9.2 0.012 13.8 0.2 3.7 2 1 1 4 4 4 1 Nucleoporin Nup120/160 MFS_1 PF07690.11 EME81332.1 - 2.1e-50 171.4 30.6 2.1e-50 171.4 21.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME81332.1 - 2e-13 49.7 12.7 2e-13 49.7 8.8 2.4 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EME81332.1 - 1.6e-06 26.6 3.6 2.7e-06 25.8 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EME81332.1 - 0.00038 18.7 0.5 0.0007 17.8 0.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF3017 PF11222.3 EME81332.1 - 0.024 14.4 0.9 0.024 14.4 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3017) OATP PF03137.15 EME81332.1 - 0.31 9.0 8.2 1 7.3 1.0 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2254 PF10011.4 EME81332.1 - 0.94 7.8 3.6 0.5 8.7 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Peptidase_M43 PF05572.8 EME81334.1 - 4.9e-10 39.2 0.0 9.9e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EME81334.1 - 2.8e-06 27.8 0.0 4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EME81334.1 - 5.2e-05 23.2 0.2 8.7e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EME81334.1 - 0.0035 17.4 0.1 0.0069 16.4 0.1 1.6 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EME81334.1 - 0.017 14.6 0.8 0.063 12.8 0.5 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EME81334.1 - 0.096 11.5 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 EME81334.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.8 EME81335.1 - 1.1e-11 44.5 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.19 EME81335.1 - 0.00078 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 EME81335.1 - 0.0028 17.2 0.7 0.021 14.3 0.5 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EME81335.1 - 0.0073 16.8 2.9 0.1 13.1 1.4 2.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EME81335.1 - 0.0098 15.8 1.4 0.095 12.6 0.9 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EME81335.1 - 0.039 14.0 0.8 0.076 13.0 0.1 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Piwi PF02171.12 EME81336.1 - 4.9e-66 222.7 0.1 5.5e-66 222.5 0.1 1.0 1 0 0 1 1 1 1 Piwi domain adh_short PF00106.20 EME81341.1 - 1.4e-17 64.1 1.1 1.8e-10 40.9 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EME81341.1 - 2.8e-14 53.4 0.1 1.3e-12 48.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME81341.1 - 3.7e-06 26.7 0.2 8.5e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EME81341.1 - 0.0012 18.9 0.1 0.0029 17.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EME81341.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 EME81341.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EME81341.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3441 PF11923.3 EME81343.1 - 1.1e-35 121.5 0.0 1.1e-35 121.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EME81343.1 - 4e-30 104.7 19.4 4e-30 104.7 13.5 3.3 2 2 1 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EME81343.1 - 6.1e-20 70.9 0.0 1.8e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Ogr_Delta PF04606.7 EME81345.1 - 0.0093 15.6 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger Fungal_trans PF04082.13 EME81346.1 - 5.2e-07 28.7 0.2 1.1e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81346.1 - 0.00087 19.1 9.5 0.0019 18.0 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSF_DNA-bind PF00447.12 EME81347.1 - 8e-32 109.5 0.1 1.6e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EME81347.1 - 5.2e-21 74.7 0.1 1.4e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain W2 PF02020.13 EME81348.1 - 8.7e-08 32.0 5.2 8.7e-08 32.0 3.6 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EME81348.1 - 1.2e-07 30.9 9.6 0.015 14.7 0.5 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EME81348.1 - 5.9e-06 25.7 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EME81348.1 - 0.0001 22.4 0.0 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EME81348.1 - 0.013 15.0 6.3 0.23 11.0 1.7 2.8 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase IBR PF01485.16 EME81349.1 - 3e-23 81.4 47.6 7.3e-12 44.9 6.3 4.6 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EME81349.1 - 7.6e-06 25.8 6.7 7.6e-06 25.8 4.7 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME81349.1 - 3.9e-05 23.3 3.7 3.9e-05 23.3 2.6 3.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EME81349.1 - 0.00011 21.7 4.4 0.00011 21.7 3.0 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME81349.1 - 0.008 15.8 7.4 0.008 15.8 5.1 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME81349.1 - 0.033 14.0 0.4 0.033 14.0 0.3 4.5 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING MFS_1 PF07690.11 EME81352.1 - 2.4e-24 85.7 52.2 8.1e-19 67.5 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1449 PF07290.6 EME81352.1 - 5.1 6.3 6.3 1.3 8.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1449) AMP-binding PF00501.23 EME81353.1 - 9.2e-64 215.3 0.1 9.2e-64 215.3 0.1 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 EME81353.1 - 1.8e-12 46.7 0.0 5.7e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 EME81353.1 - 1.5e-08 34.7 0.3 3.3e-08 33.6 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EME81353.1 - 9e-07 29.7 0.0 2.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPT PF03151.11 EME81354.1 - 1.6e-30 105.7 9.0 1.6e-30 105.7 6.2 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EME81354.1 - 0.00062 19.8 29.9 0.013 15.5 3.4 3.0 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EME81354.1 - 0.0017 17.3 17.4 0.0017 17.3 12.1 1.5 2 0 0 2 2 2 1 UAA transporter family CDC45 PF02724.9 EME81354.1 - 1.2 7.0 5.0 0.8 7.6 2.3 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF4231 PF14015.1 EME81354.1 - 1.4 8.9 5.0 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) RRM_1 PF00076.17 EME81355.1 - 9.1e-12 44.4 0.0 1.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME81355.1 - 2.5e-06 27.3 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME81355.1 - 5.6e-06 26.1 0.0 7.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME81355.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_S17 PF00366.15 EME81356.1 - 1.9e-06 27.7 4.7 3.8e-06 26.8 3.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Herpes_UL82_83 PF05784.6 EME81356.1 - 0.014 14.1 1.2 0.019 13.7 0.8 1.1 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus Helicase_C PF00271.26 EME81357.1 - 3.6e-21 74.8 0.0 1.1e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EME81357.1 - 5.3e-18 65.0 0.0 1.1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EME81357.1 - 0.00084 19.2 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME81357.1 - 0.0015 17.3 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EME81357.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain Sugar_tr PF00083.19 EME81358.1 - 8.3e-105 350.9 25.8 9.5e-105 350.7 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME81358.1 - 3.9e-28 98.1 31.5 2.9e-27 95.3 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME81358.1 - 0.017 13.5 31.6 0.0099 14.3 8.0 3.0 3 1 0 3 3 3 0 MFS/sugar transport protein MFS_1_like PF12832.2 EME81358.1 - 0.033 13.9 0.3 0.033 13.9 0.2 3.3 3 1 0 3 3 3 0 MFS_1 like family OATP PF03137.15 EME81358.1 - 0.67 7.9 11.3 0.11 10.4 2.8 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SGL PF08450.7 EME81359.1 - 1.8e-28 99.6 0.2 1e-26 93.8 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EME81359.1 - 0.00033 20.5 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Zn_clus PF00172.13 EME81360.1 - 9.6e-07 28.6 7.5 1.6e-06 27.8 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME81360.1 - 2e-06 26.8 0.2 2.1e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Toxin_18 PF08087.6 EME81361.1 - 0.054 13.2 0.6 0.23 11.2 0.4 2.2 1 0 0 1 1 1 0 Conotoxin O-superfamily DUF1227 PF06777.6 EME81363.1 - 1.7e-60 202.9 0.4 1e-59 200.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EME81363.1 - 1.4e-50 171.1 0.1 2.2e-50 170.4 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EME81363.1 - 4.2e-45 153.6 0.0 9.7e-45 152.5 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EME81363.1 - 0.00029 20.3 0.0 0.042 13.3 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EME81363.1 - 0.00051 18.9 0.0 0.003 16.4 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EME81363.1 - 0.0016 18.3 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EME81363.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME81363.1 - 0.009 16.1 0.1 1.2 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EME81363.1 - 0.07 12.3 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 EME81363.1 - 0.088 12.5 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain zf-RING_2 PF13639.1 EME81364.1 - 1.1e-09 37.9 7.9 2.1e-09 37.0 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME81364.1 - 5.6e-07 29.5 3.4 1.3e-06 28.4 2.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EME81364.1 - 1.3e-06 28.2 6.4 3.1e-06 27.0 4.4 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EME81364.1 - 8.2e-06 25.5 3.2 1.8e-05 24.4 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EME81364.1 - 0.00049 19.7 2.9 0.00049 19.7 2.0 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EME81364.1 - 0.00072 19.5 9.3 0.0014 18.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EME81364.1 - 0.0021 18.0 7.5 0.005 16.8 5.2 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 EME81364.1 - 0.0044 16.6 10.0 0.009 15.6 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME81364.1 - 0.0082 15.7 8.0 0.21 11.2 0.9 2.4 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EME81364.1 - 0.037 13.7 6.7 0.084 12.5 4.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 EME81364.1 - 0.038 13.8 1.9 0.087 12.6 1.1 1.7 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 EME81364.1 - 0.16 11.9 6.8 0.31 11.0 4.7 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EME81364.1 - 6.1 6.6 7.3 11 5.7 5.1 1.5 1 0 0 1 1 1 0 PHD-finger APH PF01636.18 EME81365.1 - 2e-14 53.8 0.0 6.3e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EME81365.1 - 0.0091 14.6 0.0 0.028 13.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) PRP3 PF08572.5 EME81366.1 - 8.1e-60 201.9 12.2 1.3e-59 201.3 8.4 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EME81366.1 - 1e-35 122.1 0.0 2.8e-35 120.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) GET2 PF08690.5 EME81366.1 - 0.93 8.6 3.8 1.6 7.8 2.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 RNA_pol_Rpb1_5 PF04998.12 EME81367.1 - 4.1e-87 291.9 0.1 7e-87 291.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EME81367.1 - 2.7e-63 212.8 0.0 5.5e-63 211.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EME81367.1 - 1.8e-32 112.2 0.0 5.4e-32 110.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EME81367.1 - 2.3e-30 106.0 0.0 1.2e-19 70.7 0.0 2.7 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EME81367.1 - 2.9e-18 65.5 0.0 1e-17 63.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rav1p_C PF12234.3 EME81367.1 - 0.22 9.6 0.0 0.33 9.0 0.0 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal APC_basic PF05956.6 EME81369.1 - 0.015 14.4 0.1 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 APC basic domain zf-C2H2_jaz PF12171.3 EME81370.1 - 0.037 14.1 0.3 0.037 14.1 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME81370.1 - 0.079 13.1 1.0 0.61 10.3 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 EME81370.1 - 6.2 6.4 8.6 11 5.5 1.5 2.7 2 0 0 2 2 2 0 InsA N-terminal domain zf-C2H2 PF00096.21 EME81370.1 - 9.7 6.7 22.3 8.9 6.8 0.8 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type RCR PF12273.3 EME81371.1 - 2e-25 89.8 8.2 2.5e-25 89.5 5.7 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4131 PF13567.1 EME81371.1 - 0.021 14.2 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Rhabdo_glycop PF00974.13 EME81371.1 - 0.03 12.5 0.1 0.04 12.1 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF1183 PF06682.7 EME81371.1 - 0.031 13.8 9.9 0.013 15.1 3.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1183) GP41 PF00517.12 EME81371.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Hum_adeno_E3A PF05393.6 EME81371.1 - 0.18 11.5 0.6 0.28 10.8 0.4 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein WBP-1 PF11669.3 EME81371.1 - 2.6 8.1 6.8 6.5 6.8 4.7 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 KASH PF10541.4 EME81371.1 - 7.8 6.4 6.9 0.31 10.9 0.7 1.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain AAA PF00004.24 EME81372.1 - 1.2e-41 141.9 0.0 7.5e-15 55.2 0.0 6.4 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EME81372.1 - 8.3e-38 129.7 0.0 2.3e-37 128.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME81372.1 - 1.1e-31 110.2 13.9 3.2e-25 89.0 0.0 5.9 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EME81372.1 - 8.3e-20 70.3 1.7 2.2e-06 27.3 0.0 5.3 4 0 0 4 4 4 4 Part of AAA domain AAA_17 PF13207.1 EME81372.1 - 2.7e-15 57.2 11.6 0.0047 17.7 0.0 6.0 6 0 0 6 6 4 4 AAA domain AAA_22 PF13401.1 EME81372.1 - 2.5e-14 53.5 12.4 0.0041 17.2 0.1 8.7 6 3 0 6 6 5 4 AAA domain AAA_5 PF07728.9 EME81372.1 - 4.9e-14 52.2 1.7 0.01 15.5 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EME81372.1 - 4.6e-11 43.1 2.9 0.072 13.3 0.0 5.5 4 0 0 4 4 4 4 AAA domain AAA_30 PF13604.1 EME81372.1 - 2.9e-10 40.0 17.7 0.0014 18.2 0.0 6.6 6 0 0 6 6 5 3 AAA domain Viral_helicase1 PF01443.13 EME81372.1 - 4.2e-10 39.5 0.2 0.16 11.4 0.0 5.8 6 0 0 6 6 6 3 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EME81372.1 - 9.3e-09 34.7 1.0 0.082 12.0 0.0 4.7 4 1 0 4 4 4 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EME81372.1 - 1.8e-08 33.7 0.6 0.11 11.5 0.0 4.9 5 0 0 5 5 5 3 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EME81372.1 - 3e-07 30.5 0.2 3.6 7.8 0.0 5.0 5 0 0 5 5 4 2 RNA helicase AAA_16 PF13191.1 EME81372.1 - 7.6e-07 29.2 23.5 0.21 11.5 0.1 7.7 7 1 0 7 7 6 3 AAA ATPase domain IstB_IS21 PF01695.12 EME81372.1 - 1.1e-06 28.1 0.3 3 7.2 0.0 4.7 4 0 0 4 4 4 2 IstB-like ATP binding protein Torsin PF06309.6 EME81372.1 - 2.7e-06 27.3 0.0 2 8.3 0.0 4.6 4 0 0 4 4 4 1 Torsin ResIII PF04851.10 EME81372.1 - 1.6e-05 24.7 0.1 0.014 15.2 0.0 4.4 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EME81372.1 - 2e-05 24.0 7.7 0.08 12.3 0.0 5.6 5 0 0 5 5 5 1 AAA domain AAA_14 PF13173.1 EME81372.1 - 6.2e-05 22.9 0.0 1.1 9.1 0.0 4.3 4 0 0 4 4 4 1 AAA domain PhoH PF02562.11 EME81372.1 - 0.00018 20.8 1.4 1.3 8.1 0.0 4.4 4 0 0 4 4 4 1 PhoH-like protein AAA_24 PF13479.1 EME81372.1 - 0.00046 19.8 10.7 2 7.9 0.1 5.0 4 1 0 4 4 4 2 AAA domain DUF2075 PF09848.4 EME81372.1 - 0.00093 18.2 12.5 0.008 15.1 0.0 6.5 7 1 0 7 7 7 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EME81372.1 - 0.001 18.2 1.3 2.8 6.9 0.0 4.2 4 0 0 4 4 4 1 KaiC ABC_tran PF00005.22 EME81372.1 - 0.0014 18.9 0.9 26 5.1 0.0 5.0 4 0 0 4 4 4 0 ABC transporter AAA_33 PF13671.1 EME81372.1 - 0.0032 17.3 22.7 0.26 11.1 0.0 6.5 7 0 0 7 7 6 2 AAA domain UvrD_C_2 PF13538.1 EME81372.1 - 0.0068 16.5 0.2 0.065 13.3 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Lon_2 PF13337.1 EME81372.1 - 0.017 13.4 0.1 5.9 5.1 0.0 3.2 3 0 0 3 3 3 0 Putative ATP-dependent Lon protease Guanylate_cyc_2 PF09778.4 EME81372.1 - 0.034 13.3 0.0 8.9 5.4 0.0 2.5 2 0 0 2 2 2 0 Guanylylate cyclase MobB PF03205.9 EME81372.1 - 0.06 13.0 0.9 46 3.7 0.0 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EME81372.1 - 0.084 12.3 3.9 2 7.8 0.0 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EME81372.1 - 0.49 10.0 2.7 88 2.7 0.0 4.1 4 0 0 4 4 4 0 NTPase Arf PF00025.16 EME81374.1 - 8.4e-45 152.1 0.0 9.9e-45 151.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EME81374.1 - 4.2e-19 68.5 0.0 4.8e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME81374.1 - 2.9e-11 43.9 0.0 5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EME81374.1 - 7.1e-09 35.1 0.0 8.1e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EME81374.1 - 4.8e-06 25.8 0.0 5.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME81374.1 - 9.3e-06 25.2 0.0 0.00019 20.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME81374.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EME81374.1 - 6e-05 21.8 0.2 0.00012 20.8 0.1 1.5 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EME81374.1 - 0.01 15.6 0.0 0.075 12.8 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 EME81374.1 - 0.021 14.1 0.3 0.047 12.9 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EME81374.1 - 0.036 13.5 0.1 0.32 10.4 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb2_6 PF00562.23 EME81375.1 - 7.2e-114 380.5 0.5 9.3e-114 380.1 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME81375.1 - 1.3e-28 99.3 0.0 1.8e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 EME81375.1 - 1.4e-26 92.2 0.0 2.8e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EME81375.1 - 1.2e-25 90.0 0.0 2.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EME81375.1 - 2.2e-24 84.9 0.0 5.7e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EME81375.1 - 2e-14 53.5 0.0 6.6e-14 51.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EME81375.1 - 0.00069 19.5 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 adh_short PF00106.20 EME81376.1 - 0.0013 18.6 0.4 0.49 10.2 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EME81376.1 - 0.0037 17.2 0.1 0.0042 17.1 0.1 1.0 1 0 0 1 1 1 1 NADH(P)-binding Glyco_hydro_3_C PF01915.17 EME81376.1 - 0.072 12.5 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain AP_endonuc_2 PF01261.19 EME81377.1 - 1.9e-27 95.9 0.4 3e-27 95.3 0.3 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SAM_MT PF04445.8 EME81377.1 - 0.045 12.8 0.4 0.079 12.1 0.3 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase U79_P34 PF03064.11 EME81377.1 - 0.099 12.1 14.5 0.18 11.2 10.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNase_H2-Ydr279 PF09468.5 EME81377.1 - 2.8 7.0 8.3 6.8 5.7 5.8 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RTA1 PF04479.8 EME81378.1 - 7.5e-55 185.8 7.6 1.1e-54 185.3 5.3 1.2 1 0 0 1 1 1 1 RTA1 like protein MENTAL PF10457.4 EME81378.1 - 1.1 8.8 5.0 2.1 7.9 0.2 2.3 2 0 0 2 2 2 0 Cholesterol-capturing domain Sugar_tr PF00083.19 EME81379.1 - 5.6e-81 272.4 28.9 6.3e-81 272.2 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME81379.1 - 7.3e-27 94.0 28.1 7.5e-26 90.6 18.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME81379.1 - 6.1e-05 21.4 4.5 6.1e-05 21.4 3.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ost4 PF10215.4 EME81379.1 - 7.1 6.2 10.7 0.26 10.8 0.3 3.3 3 0 0 3 3 3 0 Oligosaccaryltransferase DUF4287 PF14117.1 EME81380.1 - 0.13 12.0 0.0 7.2 6.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4287) Fungal_trans_2 PF11951.3 EME81382.1 - 2.8e-08 32.7 0.0 1.3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81382.1 - 7.5e-08 32.1 10.6 1.6e-07 31.0 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEMspv1-c74-12 PF11044.3 EME81383.1 - 0.69 9.4 2.5 1.2 8.6 1.8 1.5 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Gti1_Pac2 PF09729.4 EME81384.1 - 1.5e-50 171.3 0.9 1e-39 136.1 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family FUSC_2 PF13515.1 EME81386.1 - 1.9e-27 95.7 5.1 1.9e-27 95.7 3.5 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EME81386.1 - 2e-12 46.4 19.6 1.6e-09 36.9 5.2 3.4 2 2 1 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 EME81386.1 - 0.00077 18.0 15.7 0.62 8.4 0.0 3.6 3 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EME81386.1 - 0.009 15.6 0.1 0.037 13.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF3535 PF12054.3 EME81386.1 - 0.39 9.2 0.0 0.67 8.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) NapE PF06796.6 EME81386.1 - 5.5 6.3 8.4 0.31 10.3 0.5 2.7 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE OST3_OST6 PF04756.8 EME81387.1 - 3.5e-23 81.9 1.1 4.9e-23 81.4 0.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EME81387.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin PCI PF01399.22 EME81388.1 - 3.6e-18 65.7 1.0 7.3e-18 64.8 0.1 1.9 2 1 0 2 2 2 1 PCI domain TPR_12 PF13424.1 EME81388.1 - 0.018 14.9 12.7 2.9 7.9 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME81388.1 - 0.022 15.4 12.9 0.89 10.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Med2 PF11214.3 EME81388.1 - 0.024 14.6 0.1 0.11 12.5 0.1 2.2 1 1 0 1 1 1 0 Mediator complex subunit 2 TPR_7 PF13176.1 EME81388.1 - 0.024 14.4 6.8 11 6.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.4 EME81388.1 - 0.13 11.6 0.1 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 DDRGK domain TPR_3 PF07720.7 EME81388.1 - 0.24 11.2 5.6 4.7 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME81388.1 - 1 10.1 9.6 20 6.2 0.1 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat NifU_N PF01592.11 EME81389.1 - 4.1e-43 146.3 0.1 4.9e-43 146.0 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MFS_1 PF07690.11 EME81390.1 - 7.4e-32 110.4 36.7 7.4e-32 110.4 25.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EME81391.1 - 1.3e-20 74.3 0.0 2.9e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME81391.1 - 1e-19 70.1 0.0 3.5e-17 61.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME81391.1 - 9e-10 38.4 0.0 2.7e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME81391.1 - 3.7e-07 29.4 0.1 9.9e-06 24.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME81391.1 - 0.0094 15.7 0.1 0.1 12.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EME81391.1 - 0.12 11.4 0.0 9.2 5.2 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EME81392.1 - 2.4e-29 102.8 0.0 6.1e-29 101.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME81392.1 - 4.9e-15 54.7 0.0 1.8e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME81392.1 - 2.4e-09 36.5 0.0 8.8e-08 31.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME81392.1 - 9.2e-07 28.9 0.0 4.5e-05 23.4 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME81392.1 - 4e-06 26.7 0.0 0.00015 21.6 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EME81392.1 - 0.0011 19.0 0.0 0.08 13.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EME81392.1 - 0.0099 14.8 0.3 0.035 12.9 0.2 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EME81392.1 - 0.012 14.7 0.9 0.2 10.8 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EME81392.1 - 0.036 12.9 0.0 0.085 11.6 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EME81392.1 - 0.045 12.8 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.20 EME81393.1 - 2.9e-21 76.1 0.0 6.5e-21 74.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81393.1 - 4e-07 29.8 0.0 0.00012 21.8 0.1 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EME81393.1 - 0.0048 16.3 0.1 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EME81393.1 - 0.12 11.3 0.3 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lactamase_B PF00753.22 EME81394.1 - 6.1e-07 29.2 0.4 1e-06 28.5 0.3 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME81394.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 EME81395.1 - 6.7e-17 61.2 0.7 1.1e-16 60.5 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_11 PF00457.12 EME81396.1 - 0.11 11.8 0.1 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 UCH PF00443.24 EME81397.1 - 6.5e-46 156.6 0.0 1e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EME81397.1 - 2.7e-26 91.4 11.9 2.3e-21 75.6 1.2 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EME81397.1 - 1.2e-20 72.7 0.0 4.4e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EME81397.1 - 2.7e-19 69.7 0.2 6e-18 65.3 0.2 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EME81397.1 - 0.029 13.9 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Eapp_C PF10238.4 EME81397.1 - 4.4 7.2 8.6 0.54 10.1 0.9 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein I_LWEQ PF01608.12 EME81398.1 - 0.23 11.4 3.7 0.7 9.8 2.5 1.8 1 0 0 1 1 1 0 I/LWEQ domain Ank_2 PF12796.2 EME81399.1 - 1.1e-07 32.1 0.3 7.4e-07 29.4 0.2 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME81399.1 - 0.011 16.2 0.1 3.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF429 PF04250.8 EME81399.1 - 0.13 11.5 0.1 1.5 8.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF429) DUF1049 PF06305.6 EME81400.1 - 0.89 9.0 2.3 1.6 8.2 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Sugar_tr PF00083.19 EME81404.1 - 2.1e-26 92.5 12.2 2.5e-26 92.2 8.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME81404.1 - 0.015 14.0 22.0 0.02 13.6 15.2 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_2 PF13347.1 EME81404.1 - 0.026 12.9 14.6 0.35 9.2 5.5 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein MerE PF05052.7 EME81404.1 - 0.047 13.6 2.5 0.047 13.6 1.7 2.5 2 1 0 2 2 2 0 MerE protein DUF3208 PF11482.3 EME81405.1 - 0.079 13.0 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Alpha-amylase PF00128.19 EME81406.1 - 1.7e-14 53.9 0.0 4e-14 52.7 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF2563 PF10817.3 EME81408.1 - 0.0029 18.0 0.2 58 4.1 0.0 4.7 4 1 0 5 5 5 0 Protein of unknown function (DUF2563) Ribosomal_S18 PF01084.15 EME81408.1 - 0.0034 17.2 6.3 50 3.8 0.1 5.3 5 0 0 5 5 5 0 Ribosomal protein S18 DUF3222 PF11519.3 EME81408.1 - 0.0049 16.7 0.0 11 6.0 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF3222) Aerolysin PF01117.15 EME81408.1 - 0.024 13.5 0.4 14 4.4 0.1 3.3 1 1 2 3 3 3 0 Aerolysin toxin Abhydrolase_3 PF07859.8 EME81412.1 - 9.6e-35 120.0 0.0 1.1e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME81412.1 - 8.8e-07 27.9 0.0 1.4e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EME81412.1 - 0.0011 18.8 0.2 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_2 PF04909.9 EME81413.1 - 2.8e-38 132.0 0.0 3.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Dioxygenase_C PF00775.16 EME81414.1 - 1.3e-51 174.4 0.0 1.8e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EME81414.1 - 3.5e-13 49.3 0.1 5.4e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EME81414.1 - 1.9e-06 27.7 0.0 8.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain FAD_binding_3 PF01494.14 EME81415.1 - 3.5e-18 65.7 1.4 3.5e-17 62.4 1.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME81415.1 - 1.4e-09 37.3 1.0 9.3e-07 28.0 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME81415.1 - 6.1e-07 28.6 3.8 0.0011 17.9 1.1 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME81415.1 - 1.4e-06 28.1 0.5 3.2e-06 27.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME81415.1 - 4.9e-05 22.4 0.1 7.2e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME81415.1 - 6.2e-05 22.9 1.3 0.0001 22.2 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME81415.1 - 6.3e-05 22.2 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME81415.1 - 0.00021 21.6 0.3 0.00021 21.6 0.2 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME81415.1 - 0.0036 17.4 0.7 0.0093 16.0 0.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME81415.1 - 0.009 14.9 1.4 0.022 13.6 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EME81415.1 - 0.013 15.2 1.0 0.022 14.5 0.2 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EME81415.1 - 0.019 13.4 2.2 0.033 12.6 0.8 1.8 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 EME81416.1 - 2e-13 49.8 0.7 3.7e-13 48.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81416.1 - 3.7e-06 26.7 10.1 6.8e-06 25.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME81417.1 - 7.1e-40 136.7 45.3 7.1e-40 136.7 31.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME81417.1 - 2.3e-10 39.6 12.6 2.3e-10 39.6 8.7 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EME81417.1 - 9.5e-10 37.2 26.3 1.7e-09 36.4 18.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EME81418.1 - 1.6e-20 73.7 0.1 3.2e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME81418.1 - 1.3e-18 67.6 0.5 1.6e-18 67.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EME81418.1 - 4.2e-09 35.9 0.0 3.7e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EME81418.1 - 3e-06 27.0 0.2 6.3e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME81418.1 - 0.0059 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME81418.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PAE PF03283.8 EME81418.1 - 0.042 12.4 0.1 0.067 11.8 0.1 1.3 1 0 0 1 1 1 0 Pectinacetylesterase Eno-Rase_NADH_b PF12242.3 EME81418.1 - 0.054 13.2 0.2 0.15 11.8 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EME81418.1 - 0.059 13.8 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EME81418.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family zf-met2 PF12907.2 EME81419.1 - 1.3e-11 44.2 4.4 1.7e-11 43.8 3.0 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EME81419.1 - 0.00018 22.1 9.5 0.00018 22.1 6.6 1.8 2 0 0 2 2 2 1 4F5 protein family DUF1777 PF08648.7 EME81419.1 - 0.047 13.4 1.1 0.058 13.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Mucin PF01456.12 EME81419.1 - 0.15 11.8 1.7 0.16 11.7 1.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CH PF00307.26 EME81420.1 - 5.1e-58 193.7 0.0 2e-14 53.5 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EME81420.1 - 7.4e-05 22.8 0.5 0.00061 19.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EME81420.1 - 0.0009 18.8 0.0 1.6 8.4 0.0 4.0 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EME81420.1 - 0.008 15.4 1.7 1.5 8.3 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EME81420.1 - 0.1 12.5 0.9 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain DEAD PF00270.24 EME81421.1 - 5.7e-18 64.9 0.0 1.3e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME81421.1 - 4.2e-08 32.9 0.1 1.3e-07 31.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME81421.1 - 1.3e-07 31.6 0.3 3.1e-06 27.1 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EME81421.1 - 0.18 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein 2OG-FeII_Oxy_3 PF13640.1 EME81423.1 - 1.6e-09 38.1 0.0 3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EME81423.1 - 3.7e-06 26.4 0.0 1.1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COQ9 PF08511.6 EME81424.1 - 1.1e-28 98.4 0.0 1.7e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 COQ9 SNF2_N PF00176.18 EME81425.1 - 2.2e-66 223.6 0.0 3e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EME81425.1 - 8.9e-58 195.3 2.0 4e-57 193.1 2.0 1.7 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EME81425.1 - 7.1e-13 48.2 0.0 1.9e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EME81425.1 - 0.00013 20.8 0.0 0.00077 18.3 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EME81425.1 - 0.003 17.4 0.0 0.0093 15.8 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Lipase_GDSL PF00657.17 EME81427.1 - 4e-17 62.8 1.3 5.3e-17 62.4 0.9 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EME81427.1 - 4.3e-08 33.5 4.3 6.1e-08 33.0 3.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_S10 PF00450.17 EME81428.1 - 4.4e-87 292.9 2.6 6.3e-87 292.4 1.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase HALZ PF02183.13 EME81429.1 - 0.0069 16.0 1.5 0.0069 16.0 1.1 6.7 7 0 0 7 7 7 1 Homeobox associated leucine zipper RSS_P20 PF11757.3 EME81429.1 - 0.84 9.7 13.9 1.5 8.9 0.3 4.5 4 0 0 4 4 4 0 Suppressor of RNA silencing P21-like RrnaAD PF00398.15 EME81430.1 - 1.2e-56 191.6 0.0 1.8e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EME81430.1 - 2.4e-09 37.2 0.0 4.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME81430.1 - 8e-07 29.6 0.0 2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME81430.1 - 1.7e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME81430.1 - 0.00028 20.6 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME81430.1 - 0.00033 20.0 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME81430.1 - 0.00042 20.7 0.1 0.0017 18.8 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain PCMT PF01135.14 EME81430.1 - 0.00067 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EME81430.1 - 0.0011 19.3 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME81430.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 EME81430.1 - 0.049 13.9 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EME81430.1 - 0.056 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EME81430.1 - 0.064 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_28 PF02636.12 EME81430.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EME81430.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 EME81430.1 - 0.15 10.9 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase YL1 PF05764.8 EME81430.1 - 0.27 10.8 10.6 0.42 10.1 7.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RecQ5 PF06959.6 EME81431.1 - 0.057 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) AFG1_ATPase PF03969.11 EME81432.1 - 3.9e-74 249.6 0.0 8.7e-73 245.2 0.0 2.0 2 0 0 2 2 2 1 AFG1-like ATPase AAA_16 PF13191.1 EME81432.1 - 0.001 19.1 0.3 0.01 15.8 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME81432.1 - 0.0023 18.0 0.0 0.013 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EME81432.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EME81432.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AA_permease_2 PF13520.1 EME81434.1 - 1.6e-41 142.2 48.2 2e-41 141.9 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME81434.1 - 7.7e-22 77.2 38.8 1.1e-21 76.7 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease TIP_N PF12457.3 EME81434.1 - 0.049 13.7 0.0 4.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Tuftelin interacting protein N terminal Hce2 PF14856.1 EME81435.1 - 9.6e-21 73.5 0.6 1.5e-20 72.8 0.4 1.4 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Peptidase_S15 PF02129.13 EME81435.1 - 0.041 13.3 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AMP-binding PF00501.23 EME81436.1 - 1.8e-77 260.5 0.0 2.1e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME81436.1 - 3.4e-14 53.5 0.0 6.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Catalase PF00199.14 EME81437.1 - 8e-11 41.2 0.0 3.7e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 Catalase Vac14_Fig4_bd PF11916.3 EME81438.1 - 6.1e-80 266.6 6.7 1.2e-79 265.7 4.6 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EME81438.1 - 4.1e-47 158.5 0.5 1.2e-43 147.4 0.1 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EME81438.1 - 1.8e-08 33.7 5.0 0.00019 21.2 0.0 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EME81438.1 - 2.1e-08 34.4 6.9 0.00018 21.8 0.0 5.2 4 1 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EME81438.1 - 4.8e-08 33.1 5.4 0.0021 18.3 0.1 5.4 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.18 EME81438.1 - 0.014 15.1 0.2 11 6.0 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ParcG PF10274.4 EME81438.1 - 0.025 14.4 0.3 9.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Parkin co-regulated protein UME PF08064.8 EME81438.1 - 0.23 11.4 2.1 3.3 7.7 0.0 3.2 3 0 0 3 3 3 0 UME (NUC010) domain DUF4023 PF13215.1 EME81438.1 - 0.38 10.5 2.5 0.57 10.0 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) RNA_pol_Rpb5_C PF01191.14 EME81439.1 - 1.7e-32 110.8 0.2 2.9e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EME81439.1 - 2.5e-28 98.3 0.0 3.6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EME81439.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease SLT PF01464.15 EME81440.1 - 4.4e-05 22.9 3.3 0.0025 17.3 0.0 3.0 1 1 2 3 3 3 2 Transglycosylase SLT domain Herpes_LMP1 PF05297.6 EME81440.1 - 5.5 5.8 10.3 0.34 9.8 2.2 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Gloverin PF10793.4 EME81441.1 - 0.028 14.0 0.2 0.073 12.7 0.1 1.8 1 1 1 2 2 2 0 Gloverin-like protein PHO4 PF01384.15 EME81444.1 - 9.3e-99 330.1 20.3 1.1e-98 329.9 14.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family ADH_N PF08240.7 EME81446.1 - 3.4e-05 23.5 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME81446.1 - 0.0065 16.0 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PAF-AH_p_II PF03403.8 EME81446.1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Sugar_tr PF00083.19 EME81447.1 - 2.2e-75 253.9 19.8 3.2e-75 253.4 13.7 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME81447.1 - 4.3e-23 81.5 61.6 1.1e-15 57.2 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec23_trunk PF04811.10 EME81450.1 - 6.7e-48 163.1 0.0 2.3e-47 161.4 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EME81450.1 - 1.8e-23 81.9 0.0 2.9e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EME81450.1 - 1.7e-18 66.8 0.6 2.9e-18 66.1 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EME81450.1 - 1.7e-16 59.4 4.0 3.4e-16 58.4 2.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EME81450.1 - 4.4e-06 26.2 0.0 1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DUF976 PF06162.7 EME81450.1 - 0.22 11.0 0.0 0.99 8.8 0.0 1.9 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF976) Fungal_trans PF04082.13 EME81452.1 - 2.2e-11 43.1 0.4 3.5e-11 42.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EBV-NA3 PF05009.7 EME81453.1 - 6.2 5.9 12.9 1.5 7.9 1.4 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CYSTM PF12734.2 EME81454.1 - 1.2 9.2 71.8 8.7 6.5 6.0 4.9 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance DUF1517 PF07466.6 EME81454.1 - 2.4 7.0 3.8 3 6.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TYA PF01021.14 EME81454.1 - 3.7 7.7 6.0 5.6 7.2 4.2 1.4 1 0 0 1 1 1 0 TYA transposon protein Herpes_gE PF02480.11 EME81455.1 - 0.037 12.2 0.1 0.037 12.2 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ery_res_leader2 PF08057.6 EME81456.1 - 0.26 11.4 1.8 2 8.6 0.1 2.4 2 0 0 2 2 2 0 Erythromycin resistance leader peptide E1-E2_ATPase PF00122.15 EME81458.1 - 5.9e-77 257.7 0.3 1.1e-76 256.9 0.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME81458.1 - 7.3e-39 133.1 0.4 7.3e-39 133.1 0.3 1.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME81458.1 - 1.4e-30 107.2 0.0 4e-29 102.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME81458.1 - 1.8e-18 65.7 0.1 3.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EME81458.1 - 9.3e-15 55.2 0.0 2.5e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME81458.1 - 4.5e-14 52.1 0.0 9.4e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME81458.1 - 5.7e-05 22.8 1.2 0.00038 20.1 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EME81459.1 - 5.2e-37 126.2 0.1 1.6e-36 124.6 0.0 1.9 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EME81459.1 - 4.8e-07 28.8 0.0 1.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EME81459.1 - 0.97 8.9 5.7 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 ScpA/B protein ExoD PF06055.7 EME81466.1 - 0.099 11.7 0.2 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Exo_endo_phos PF03372.18 EME81467.1 - 3.4e-19 69.7 0.0 4.6e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4337 PF14235.1 EME81467.1 - 0.82 9.4 0.0 0.82 9.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) CorA PF01544.13 EME81468.1 - 2.6e-40 138.2 0.8 2.8e-39 134.9 0.6 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1682 PF07946.9 EME81470.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Phage_holin_4 PF05105.7 EME81470.1 - 0.15 11.7 0.2 0.18 11.4 0.2 1.3 1 0 0 1 1 1 0 Holin family Allantoicase PF03561.10 EME81471.1 - 8e-96 317.5 0.1 1.8e-53 180.0 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Ank_2 PF12796.2 EME81472.1 - 6.4e-19 68.0 0.1 1.4e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DIL PF01843.14 EME81472.1 - 1.8e-17 63.1 5.0 3.8e-16 58.8 1.6 2.7 2 1 0 2 2 2 1 DIL domain Ank PF00023.25 EME81472.1 - 2.4e-15 55.4 0.1 1.2e-05 24.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EME81472.1 - 5.2e-14 51.9 0.4 9.6e-10 38.3 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME81472.1 - 3.3e-11 43.3 0.3 0.00012 22.4 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME81472.1 - 1.5e-07 30.9 0.0 0.11 12.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Allantoicase PF03561.10 EME81473.1 - 2.7e-56 189.2 0.0 9.2e-51 171.2 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 EME81474.1 - 1.9e-30 104.8 0.0 4.6e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME81474.1 - 2.1e-22 79.2 0.1 2.6e-21 75.7 0.0 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EME81474.1 - 2e-20 72.5 1.2 4.1e-20 71.5 0.0 2.3 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EME81474.1 - 1.6e-15 57.5 1.4 2.7e-13 50.2 0.0 4.1 4 0 0 4 4 3 1 AAA ATPase domain GAF_3 PF13492.1 EME81474.1 - 1.8e-11 44.2 0.0 3.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EME81474.1 - 5.3e-11 42.1 0.0 1.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.1 EME81474.1 - 1.9e-08 34.9 0.0 4.9e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EME81474.1 - 1.4e-07 31.7 0.0 5.8e-07 29.7 0.0 2.2 2 0 0 2 2 1 1 GAF domain Pkinase_Tyr PF07714.12 EME81474.1 - 1.6e-07 30.7 0.0 3.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.7 EME81474.1 - 0.00014 21.5 0.0 0.62 9.6 0.0 3.2 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 EME81474.1 - 0.00083 19.5 0.0 0.016 15.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain HATPase_c_3 PF13589.1 EME81474.1 - 0.0036 16.9 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ArgK PF03308.11 EME81474.1 - 0.0076 15.0 1.1 0.0099 14.6 0.0 1.7 2 0 0 2 2 2 1 ArgK protein NB-ARC PF00931.17 EME81474.1 - 0.0079 15.0 0.1 0.036 12.9 0.1 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EME81474.1 - 0.24 11.3 12.4 0.16 11.9 0.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME81474.1 - 5.7 7.8 12.0 0.54 11.0 0.1 5.2 5 1 0 5 5 4 0 Tetratricopeptide repeat ATP_bind_1 PF03029.12 EME81477.1 - 4.4e-77 258.8 0.0 5.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EME81477.1 - 9.1e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME81477.1 - 0.00012 22.8 0.0 0.00043 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EME81477.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EME81477.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EME81477.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EME81477.1 - 0.004 16.8 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain cobW PF02492.14 EME81477.1 - 0.0065 15.9 0.0 0.033 13.6 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EME81477.1 - 0.0083 15.7 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EME81477.1 - 0.0089 15.4 0.0 3.9 6.8 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EME81477.1 - 0.012 15.5 0.0 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.17 EME81477.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EME81477.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EME81477.1 - 0.017 15.4 0.0 0.11 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EME81477.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EME81477.1 - 0.018 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EME81477.1 - 0.019 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EME81477.1 - 0.019 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EME81477.1 - 0.019 14.6 0.1 0.097 12.3 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 EME81477.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.1 EME81477.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME81477.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EME81477.1 - 0.031 13.7 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EME81477.1 - 0.032 13.9 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EME81477.1 - 0.037 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME81477.1 - 0.05 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EME81477.1 - 0.058 12.8 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArsA_ATPase PF02374.10 EME81477.1 - 0.061 12.3 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase CbiA PF01656.18 EME81477.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.9 EME81477.1 - 0.063 12.2 0.0 0.067 12.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain KaiC PF06745.8 EME81477.1 - 0.07 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EME81477.1 - 0.083 12.2 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EME81477.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase His_Phos_1 PF00300.17 EME81478.1 - 4.6e-16 59.3 0.0 6.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SLAC1 PF03595.12 EME81479.1 - 1.9e-54 184.5 42.1 2.1e-54 184.3 29.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RasGEF PF00617.14 EME81480.1 - 1.4e-46 158.6 0.3 1.8e-46 158.2 0.2 1.1 1 0 0 1 1 1 1 RasGEF domain Ribosomal_L44 PF00935.14 EME81483.1 - 2.4e-35 120.4 12.2 3.4e-35 119.8 8.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 4HBT PF03061.17 EME81484.1 - 6.8e-12 45.3 0.5 1.1e-11 44.7 0.4 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DDHD PF02862.12 EME81485.1 - 1.2e-66 224.7 2.2 8.4e-65 218.7 0.0 3.3 3 1 0 3 3 3 1 DDHD domain Abhydrolase_5 PF12695.2 EME81485.1 - 0.018 14.7 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 EME81485.1 - 0.031 13.5 0.1 0.088 12.0 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 EME81485.1 - 0.094 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Pkinase PF00069.20 EME81486.1 - 5.8e-34 117.4 0.0 3.8e-26 91.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME81486.1 - 2.2e-15 56.4 0.0 1.1e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EME81486.1 - 0.0084 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cytidylate_kin2 PF13189.1 EME81486.1 - 0.011 15.7 0.1 0.047 13.6 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family Pox_ser-thr_kin PF05445.6 EME81486.1 - 0.17 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ODC_AZ PF02100.12 EME81487.1 - 1.2e-21 76.2 0.0 1.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme KilA-N PF04383.8 EME81488.1 - 1.2e-05 24.9 0.0 0.00019 20.9 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain MSC PF09402.5 EME81491.1 - 1.9e-86 289.8 0.0 2.6e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EME81491.1 - 5.9e-18 64.1 0.1 1.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 EME81491.1 - 7.9e-06 25.3 0.1 1.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein SlyX PF04102.7 EME81491.1 - 0.045 14.1 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 0 SlyX Zn_clus PF00172.13 EME81492.1 - 1.3e-09 37.7 12.4 2.2e-09 37.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME81492.1 - 0.0023 16.5 0.1 0.003 16.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 EME81493.1 - 0.022 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HTH_3 PF01381.17 EME81493.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Ank_3 PF13606.1 EME81493.1 - 0.11 12.8 0.2 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat ArsB PF02040.10 EME81494.1 - 4.2e-19 68.8 22.4 5.4e-11 42.1 3.5 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein SKG6 PF08693.5 EME81494.1 - 0.052 12.8 1.6 0.19 11.0 1.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAD_2 PF13419.1 EME81495.1 - 1.1e-26 94.0 0.0 1.4e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CagY_M PF07337.6 EME81495.1 - 3.5 7.1 6.1 1.5 8.3 1.6 2.1 2 0 0 2 2 2 0 DC-EC Repeat Bap31 PF05529.7 EME81497.1 - 0.21 11.0 2.6 0.39 10.1 1.8 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Fringe PF02434.11 EME81499.1 - 0.00083 18.6 0.4 0.013 14.7 0.3 2.1 1 1 0 1 1 1 1 Fringe-like PI-PLC-X PF00388.14 EME81500.1 - 0.021 14.2 0.0 0.67 9.3 0.0 2.3 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Med4 PF10018.4 EME81501.1 - 4.5e-30 104.4 3.8 7e-30 103.8 2.7 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 OSCP PF00213.13 EME81501.1 - 0.044 13.6 0.6 0.082 12.7 0.4 1.4 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Ppx-GppA PF02541.11 EME81502.1 - 5.3e-39 134.1 0.0 9.2e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family RNase_H2-Ydr279 PF09468.5 EME81502.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Methyltransf_11 PF08241.7 EME81503.1 - 2.2e-14 53.6 0.0 4.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME81503.1 - 5.7e-13 49.4 0.1 1.5e-12 48.0 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME81503.1 - 1.7e-10 40.6 0.0 3.3e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME81503.1 - 1.1e-09 38.6 0.1 5.9e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME81503.1 - 1.6e-09 37.6 0.0 3.6e-09 36.5 0.0 1.5 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME81503.1 - 1.3e-08 35.0 0.0 3.7e-08 33.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME81503.1 - 3.7e-07 29.5 0.0 5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME81503.1 - 3.2e-06 27.1 0.6 1e-05 25.5 0.2 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EME81503.1 - 2.3e-05 23.8 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EME81503.1 - 3.5e-05 23.0 0.1 6.4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EME81503.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_8 PF05148.10 EME81503.1 - 0.0027 17.3 0.0 0.0089 15.6 0.0 1.8 1 1 1 2 2 2 1 Hypothetical methyltransferase LpxK PF02606.9 EME81503.1 - 0.12 11.2 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase zf-UBR PF02207.15 EME81505.1 - 2.4e-17 62.4 16.5 2.4e-17 62.4 11.5 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EME81505.1 - 2.8e-07 30.1 0.1 9e-07 28.5 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EME81505.1 - 0.00056 19.6 1.1 0.00056 19.6 0.8 4.4 4 1 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EME81505.1 - 0.0069 16.0 0.6 0.0069 16.0 0.4 4.2 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME81505.1 - 0.013 15.4 0.6 0.013 15.4 0.4 4.2 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) UCR_UQCRX_QCR9 PF05365.7 EME81506.1 - 5.1e-22 77.2 2.1 5.6e-22 77.1 1.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EME81507.1 - 6.3e-13 48.0 1.4 1.3e-12 47.0 1.0 1.6 1 0 0 1 1 1 1 Mago binding DUF4407 PF14362.1 EME81507.1 - 0.82 8.5 10.6 0.96 8.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.3 EME81507.1 - 3.2 6.3 13.4 4.4 5.9 9.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Band_7 PF01145.20 EME81509.1 - 1.1e-15 58.0 0.6 1.1e-15 58.0 0.4 2.6 2 1 1 3 3 3 1 SPFH domain / Band 7 family F-box PF00646.28 EME81510.1 - 2.3e-05 23.9 0.1 5.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME81510.1 - 0.034 13.8 0.2 0.034 13.8 0.1 2.3 3 0 0 3 3 3 0 F-box-like PPR_2 PF13041.1 EME81511.1 - 4.2e-09 36.2 0.2 0.086 12.8 0.0 4.8 4 1 2 6 6 6 3 PPR repeat family PPR PF01535.15 EME81511.1 - 2.5e-05 23.9 1.4 0.69 10.0 0.0 5.2 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EME81511.1 - 0.0034 17.8 0.0 32 5.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_3 PF13812.1 EME81511.1 - 0.0034 17.5 3.0 2.8 8.4 0.0 5.5 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Ribosomal_S18 PF01084.15 EME81512.1 - 3.5e-12 45.9 0.3 1.3e-11 44.1 0.0 2.0 3 0 0 3 3 3 1 Ribosomal protein S18 Carboxyl_trans PF01039.17 EME81513.1 - 1.5e-83 280.8 0.0 1.8e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain DUF1296 PF06972.6 EME81513.1 - 0.0076 16.1 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) Ribosomal_L18e PF00828.14 EME81514.1 - 8.5e-34 116.7 0.0 1.2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 VID27 PF08553.5 EME81515.1 - 0 1087.9 2.0 0 1087.7 1.4 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein zf-CCCH PF00642.19 EME81516.1 - 1.4e-09 37.4 8.9 3.5e-05 23.3 0.6 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EME81516.1 - 0.0024 17.7 14.0 0.13 12.2 2.5 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Toxin_20 PF08089.6 EME81516.1 - 2.2 8.2 6.1 0.69 9.8 1.8 1.8 1 1 1 2 2 2 0 Huwentoxin-II family Thi4 PF01946.12 EME81519.1 - 3.7e-100 333.7 0.1 4.5e-100 333.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EME81519.1 - 2.6e-09 36.4 0.4 1.4e-08 34.0 0.4 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME81519.1 - 1.5e-05 24.9 0.4 3.7e-05 23.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME81519.1 - 1.7e-05 23.9 0.7 3.5e-05 22.8 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME81519.1 - 0.00018 21.3 1.1 0.00027 20.7 0.0 1.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME81519.1 - 0.0011 18.8 0.1 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME81519.1 - 0.0017 18.4 0.1 0.0028 17.7 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME81519.1 - 0.0029 16.5 4.1 0.0049 15.7 0.9 2.2 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 EME81519.1 - 0.014 14.5 0.1 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME81519.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EME81519.1 - 0.084 11.3 0.4 0.44 8.9 0.6 1.8 2 0 0 2 2 2 0 HI0933-like protein Lipocalin_5 PF13924.1 EME81521.1 - 7.8e-26 90.4 0.0 1.1e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain WD40 PF00400.27 EME81522.1 - 4.7e-06 26.2 6.3 0.15 11.9 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME81522.1 - 0.18 11.3 0.1 0.18 11.3 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DSBA PF01323.15 EME81523.1 - 1.2e-25 90.2 0.0 1.4e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Cut8_N PF14482.1 EME81524.1 - 0.4 10.7 0.1 0.4 10.7 0.1 3.5 4 0 0 4 4 4 0 Cut8 proteasome-binding domain GMC_oxred_N PF00732.14 EME81525.1 - 5.1e-78 262.2 0.0 6.8e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME81525.1 - 6.5e-35 120.5 0.1 1.8e-34 119.1 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EME81525.1 - 8.1e-05 21.6 0.2 0.038 12.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME81525.1 - 0.00068 18.5 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EME81525.1 - 0.0029 16.6 0.1 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EME81525.1 - 0.087 11.9 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EME81525.1 - 0.2 12.0 0.3 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TFIID-18kDa PF02269.11 EME81527.1 - 5.7e-29 99.7 1.0 2.4e-28 97.7 0.4 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EME81527.1 - 0.0059 16.6 0.6 0.015 15.3 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAM177 PF14774.1 EME81527.1 - 0.067 13.1 1.3 0.15 12.0 0.9 1.5 1 0 0 1 1 1 0 FAM177 family TP_methylase PF00590.15 EME81528.1 - 6.3e-20 71.7 0.1 1.5e-19 70.5 0.1 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases FA_desaturase PF00487.19 EME81529.1 - 7.3e-39 133.7 24.1 1.1e-38 133.2 16.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EME81529.1 - 1.9e-15 56.4 0.0 4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM60A PF15396.1 EME81529.1 - 0.071 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Myb_DNA-binding PF00249.26 EME81533.1 - 1.2e-17 63.7 1.9 1.4e-10 41.0 0.1 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME81533.1 - 1.3e-12 47.6 1.3 1.9e-08 34.2 0.0 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain HsbA PF12296.3 EME81535.1 - 6e-25 87.5 10.5 6e-25 87.5 7.3 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A COG2 PF06148.6 EME81535.1 - 0.063 13.1 0.0 5.7 6.8 0.0 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CO_deh_flav_C PF03450.12 EME81535.1 - 0.2 11.5 5.9 0.28 11.1 0.7 2.6 3 0 0 3 3 3 0 CO dehydrogenase flavoprotein C-terminal domain LPP PF04728.8 EME81535.1 - 1.1 9.1 9.6 3.2 7.6 2.7 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PALP PF00291.20 EME81536.1 - 7.6e-50 169.8 1.2 9.1e-50 169.6 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4454 PF14628.1 EME81536.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Hydantoinase_B PF02538.9 EME81537.1 - 4.1e-201 668.7 0.4 2.3e-199 663.0 0.3 2.3 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EME81537.1 - 8.6e-94 313.8 0.1 1.9e-93 312.7 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EME81537.1 - 1.8e-57 193.6 1.9 2.9e-56 189.7 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Abhydrolase_2 PF02230.11 EME81538.1 - 4.5e-34 117.7 0.0 6.7e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EME81538.1 - 2.2e-08 33.9 0.0 5.6e-08 32.6 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME81538.1 - 4.3e-05 23.4 0.2 0.0029 17.5 0.1 2.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EME81538.1 - 7.7e-05 22.2 0.0 0.00032 20.2 0.0 1.9 1 1 1 2 2 2 2 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EME81538.1 - 0.00026 20.2 0.0 0.011 14.9 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family ThiF PF00899.16 EME81539.1 - 1.2e-39 135.2 0.0 2.3e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EME81539.1 - 1.2e-25 88.8 0.8 1.7e-18 66.0 0.2 2.5 2 0 0 2 2 2 2 MoeZ/MoeB domain Rhodanese PF00581.15 EME81539.1 - 9e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EME81539.1 - 0.062 13.3 0.1 0.31 11.1 0.1 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mg_trans_NIPA PF05653.9 EME81540.1 - 1.2e-79 267.4 25.4 4e-79 265.6 17.6 1.6 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EME81540.1 - 2.1e-09 37.5 4.0 2.1e-09 37.5 2.7 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EME81540.1 - 3.2e-07 30.4 9.3 3.2e-07 30.4 6.4 3.3 3 1 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EME81540.1 - 1e-05 24.7 8.1 2.3e-05 23.6 1.4 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF4131 PF13567.1 EME81540.1 - 5.6 6.3 11.7 6.2 6.1 1.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) COG4 PF08318.7 EME81541.1 - 4.2e-96 321.5 0.0 6e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Nsp1_C PF05064.8 EME81541.1 - 0.13 11.9 1.2 2.8 7.5 0.1 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region Sec6 PF06046.8 EME81541.1 - 0.17 9.9 0.2 1.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec6 UPF0184 PF03670.8 EME81541.1 - 0.21 11.7 2.3 0.99 9.6 0.3 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) FA_hydroxylase PF04116.8 EME81542.1 - 2e-14 53.9 15.9 2e-14 53.9 11.0 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Patatin PF01734.17 EME81543.1 - 2e-24 86.6 0.0 3.4e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase MOSC PF03473.12 EME81544.1 - 4.3e-15 55.3 0.0 6.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EME81544.1 - 4.7e-13 48.9 0.0 8.1e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain EFhand_Ca_insen PF08726.5 EME81546.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Amino_oxidase PF01593.19 EME81547.1 - 6.5e-22 78.2 0.0 3.5e-15 56.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME81547.1 - 4.9e-12 45.7 0.0 1.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME81547.1 - 1.2e-06 27.6 0.0 3.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME81547.1 - 5.3e-05 22.4 0.0 0.0094 15.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 EME81547.1 - 0.0091 16.3 0.0 0.5 10.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME81547.1 - 0.078 12.0 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase PP2C PF00481.16 EME81550.1 - 1.9e-51 174.9 0.0 3.3e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EME81550.1 - 8.3e-47 156.1 62.3 6.6e-08 32.0 0.3 13.3 5 3 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME81550.1 - 1e-40 137.2 61.4 5.7e-11 42.0 0.9 11.9 6 4 6 13 13 13 9 Leucine rich repeat Guanylate_cyc PF00211.15 EME81550.1 - 6.3e-30 103.9 0.0 1.3e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EME81550.1 - 7.9e-22 73.9 57.5 0.027 14.4 0.0 19.8 18 2 2 20 20 20 7 Leucine Rich Repeat RA PF00788.18 EME81550.1 - 7.2e-11 42.4 0.0 2.4e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EME81550.1 - 4.5e-10 38.0 54.2 0.062 13.5 0.1 16.7 17 0 0 17 17 16 3 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 EME81550.1 - 5e-07 28.9 0.2 1.7e-06 27.2 0.2 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.1 EME81550.1 - 2.5e-05 23.9 0.8 0.49 10.0 0.1 3.9 4 0 0 4 4 4 1 Leucine rich repeats (6 copies) LRR_6 PF13516.1 EME81550.1 - 0.00018 21.2 49.9 5.4 7.4 0.1 15.6 16 2 3 19 19 19 2 Leucine Rich repeat LRR_9 PF14580.1 EME81550.1 - 0.0035 16.9 7.2 0.28 10.7 0.1 4.1 2 1 2 4 4 4 1 Leucine-rich repeat DNA_primase_S PF01896.14 EME81551.1 - 7.5e-56 187.9 0.2 1.6e-55 186.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF1917 PF08939.5 EME81552.1 - 2.5e-50 171.5 0.0 5e-50 170.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Menin PF05053.8 EME81555.1 - 0.026 12.7 0.4 0.028 12.6 0.3 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EME81557.1 - 8e-75 251.3 0.0 1.1e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81557.1 - 6.2e-32 110.6 0.0 7.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME81557.1 - 0.0004 19.4 0.0 0.00079 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME81557.1 - 0.0023 17.0 0.1 0.004 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME81557.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EME81557.1 - 0.038 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ABC_membrane PF00664.18 EME81558.1 - 1.3e-35 123.1 11.8 1.8e-35 122.6 8.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EME81558.1 - 9.4e-35 119.8 0.0 2.2e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME81558.1 - 3.8e-07 30.3 0.1 0.00029 20.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EME81558.1 - 4.3e-07 29.4 0.1 8.3e-05 21.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EME81558.1 - 0.00019 21.5 0.0 0.00062 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME81558.1 - 0.00026 20.2 0.0 0.00063 18.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME81558.1 - 0.00031 21.5 0.1 0.00092 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME81558.1 - 0.0004 20.4 0.1 0.0049 16.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EME81558.1 - 0.00061 19.7 0.0 0.0057 16.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EME81558.1 - 0.003 17.7 0.0 0.021 15.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EME81558.1 - 0.0036 16.7 0.1 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EME81558.1 - 0.017 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME81558.1 - 0.036 14.0 0.4 0.082 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EME81558.1 - 0.047 13.5 0.8 0.3 10.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EME81558.1 - 0.05 12.4 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 EME81558.1 - 0.066 13.5 0.7 0.12 12.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EME81558.1 - 0.068 12.6 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EME81558.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EME81558.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EME81558.1 - 0.079 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 EME81559.1 - 3e-17 63.0 0.0 4.9e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EME81559.1 - 1e-13 51.2 0.0 3.8e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EME81559.1 - 2.4e-11 43.0 0.0 1.8e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EME81559.1 - 8.7e-09 35.2 0.1 2.3e-08 33.9 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_30 PF13604.1 EME81559.1 - 1.6e-07 31.0 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME81559.1 - 1.7e-07 31.4 0.3 1.2e-06 28.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME81559.1 - 4.6e-07 30.0 0.0 1.9e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EME81559.1 - 3.8e-06 26.6 0.2 1.6e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EME81559.1 - 4.6e-06 26.2 0.0 1.3e-05 24.8 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EME81559.1 - 9.9e-06 24.7 0.1 3.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EME81559.1 - 1.2e-05 24.9 0.2 0.0004 20.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EME81559.1 - 1.8e-05 24.6 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EME81559.1 - 2.8e-05 23.1 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 EME81559.1 - 3.5e-05 23.3 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EME81559.1 - 4.4e-05 22.3 0.0 0.17 10.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus PhoH PF02562.11 EME81559.1 - 0.00014 21.1 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EME81559.1 - 0.00015 21.4 0.2 0.00077 19.0 0.1 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EME81559.1 - 0.00017 20.6 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 EME81559.1 - 0.00024 20.6 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 EME81559.1 - 0.00024 20.7 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EME81559.1 - 0.0011 18.4 0.3 0.024 14.1 0.1 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EME81559.1 - 0.0022 17.4 0.2 0.017 14.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EME81559.1 - 0.0031 16.7 0.0 0.024 13.7 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EME81559.1 - 0.0043 16.5 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 EME81559.1 - 0.009 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EME81559.1 - 0.011 15.5 0.0 0.27 11.0 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EME81559.1 - 0.013 14.9 0.7 3.9 6.8 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EME81559.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME81559.1 - 0.019 15.7 0.0 0.036 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EME81559.1 - 0.021 13.6 0.0 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain RNA_helicase PF00910.17 EME81559.1 - 0.027 14.6 0.1 0.063 13.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EME81559.1 - 0.046 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EME81559.1 - 0.056 13.1 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EME81559.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EME81559.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF953 PF06110.6 EME81560.1 - 1.4e-08 34.2 0.0 2.3e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) UBA_4 PF14555.1 EME81562.1 - 3.6e-05 23.1 0.0 7.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EME81562.1 - 0.0087 15.8 0.1 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Adap_comp_sub PF00928.16 EME81563.1 - 4.8e-83 278.2 0.0 6.1e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME81563.1 - 0.00032 20.4 0.2 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ORC2 PF04084.9 EME81564.1 - 1.7e-103 345.9 0.0 2e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FliH PF02108.11 EME81564.1 - 0.041 13.7 0.1 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Flagellar assembly protein FliH WRW PF10206.4 EME81566.1 - 0.043 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f API5 PF05918.6 EME81567.1 - 8.6 4.7 6.9 12 4.1 4.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cupin_2 PF07883.6 EME81569.1 - 1.4e-07 30.9 1.6 8.4e-06 25.1 1.1 2.2 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EME81569.1 - 1.6e-06 27.6 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EME81569.1 - 8.9e-05 21.8 0.1 0.00022 20.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EME81569.1 - 0.0059 16.2 0.4 0.052 13.1 0.3 2.2 1 1 0 1 1 1 1 Cupin NAD_binding_2 PF03446.10 EME81570.1 - 1e-35 123.0 0.0 1.4e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME81570.1 - 1.7e-19 70.0 0.0 2.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EME81570.1 - 6.7e-06 26.4 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EME81570.1 - 0.014 14.1 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EME81570.1 - 0.11 13.0 0.0 0.41 11.1 0.0 1.9 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1560 PF07597.6 EME81571.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1560) DUF605 PF04652.11 EME81571.1 - 0.21 10.9 7.0 0.23 10.8 4.9 1.1 1 0 0 1 1 1 0 Vta1 like TetR_C_6 PF13977.1 EME81571.1 - 0.21 11.5 3.0 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial transcriptional repressor GMC_oxred_N PF00732.14 EME81572.1 - 9.2e-52 176.0 0.0 1.3e-51 175.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME81572.1 - 4.5e-39 134.0 0.1 1e-38 132.9 0.1 1.6 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME81572.1 - 1.1e-06 27.8 0.7 1e-05 24.6 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME81572.1 - 1.6e-05 24.0 0.2 0.00035 19.5 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME81572.1 - 0.0004 19.4 0.5 0.0022 16.9 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EME81572.1 - 0.00063 19.7 1.3 0.002 18.1 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME81572.1 - 0.0018 18.3 1.2 0.41 10.6 0.3 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME81572.1 - 0.0045 16.9 0.3 0.01 15.7 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME81572.1 - 0.026 13.5 0.3 0.047 12.7 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EME81572.1 - 0.082 11.3 0.3 0.12 10.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EME81572.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EME81572.1 - 0.12 11.4 0.3 0.29 10.1 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EME81572.1 - 0.19 12.1 0.4 0.54 10.6 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME81572.1 - 0.19 11.7 0.2 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Aminotran_1_2 PF00155.16 EME81573.1 - 2.1e-81 273.6 0.0 3e-81 273.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME81573.1 - 8.2e-09 34.6 0.1 1.7e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EME81573.1 - 7.7e-06 24.4 0.0 1.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME81573.1 - 0.00019 20.5 0.2 0.00035 19.7 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.3 EME81573.1 - 0.001 17.4 0.1 0.0015 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Beta_elim_lyase PF01212.16 EME81573.1 - 0.0094 15.1 2.2 0.023 13.8 1.5 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Methyltransf_31 PF13847.1 EME81573.1 - 0.018 14.6 0.0 2 7.9 0.0 2.5 1 1 0 2 2 2 0 Methyltransferase domain TrkH PF02386.11 EME81574.1 - 2e-126 421.3 16.0 1.3e-122 408.8 4.9 2.1 2 0 0 2 2 2 2 Cation transport protein ADH_zinc_N_2 PF13602.1 EME81575.1 - 1.7e-13 51.5 0.1 2.1e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EME81575.1 - 5.4e-10 38.9 0.4 3.7e-09 36.2 0.1 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME81575.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Oxidored_nitro PF00148.14 EME81575.1 - 0.059 11.9 0.0 0.094 11.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F-box-like PF12937.2 EME81576.1 - 0.0077 15.9 0.1 0.056 13.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like P3A PF08727.6 EME81576.1 - 0.035 13.4 0.7 0.082 12.2 0.0 1.9 2 0 0 2 2 2 0 Poliovirus 3A protein like G_glu_transpept PF01019.16 EME81579.1 - 1.6e-152 508.5 0.1 1.9e-152 508.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Gln-synt_C PF00120.19 EME81580.1 - 4.8e-47 160.2 0.0 6e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF647 PF04884.9 EME81581.1 - 8e-73 244.7 2.9 1e-72 244.3 2.0 1.0 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Pox_P35 PF03213.9 EME81581.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein DUF204 PF02659.10 EME81581.1 - 1.9 8.6 5.7 1.2 9.2 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF DLH PF01738.13 EME81582.1 - 7e-24 84.3 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME81582.1 - 4.7e-08 32.8 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME81582.1 - 0.0045 16.9 0.0 0.044 13.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME81582.1 - 0.025 14.1 0.0 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EME81583.1 - 2.5e-52 177.9 0.0 2.9e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EME81583.1 - 1.7e-07 31.3 0.1 2.3e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME81583.1 - 3.1e-05 23.6 0.1 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EME81583.1 - 0.00024 20.8 0.0 0.00044 20.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EME81583.1 - 0.016 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EME81583.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1399 PF07173.7 EME81584.1 - 1.5e-22 80.3 1.8 1.3e-18 67.5 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) P21-Arc PF04062.9 EME81585.1 - 1.8e-80 268.7 0.0 2.1e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF1282 PF06930.7 EME81586.1 - 0.0041 16.7 0.1 0.005 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) MARVEL PF01284.18 EME81586.1 - 0.0092 15.8 0.3 0.012 15.4 0.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EME81586.1 - 0.92 8.7 3.8 1.4 8.1 2.6 1.2 1 1 0 1 1 1 0 Tetraspanin family UPRTase PF14681.1 EME81588.1 - 7.9e-78 260.3 0.0 1.1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EME81588.1 - 0.00064 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain WAPL PF07814.8 EME81590.1 - 6.1e-15 54.8 2.8 1.1e-13 50.7 1.9 2.2 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF2339 PF10101.4 EME81590.1 - 0.74 8.0 0.2 1 7.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Ras PF00071.17 EME81591.1 - 1.5e-45 154.5 0.1 1.7e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME81591.1 - 1.6e-15 57.6 0.1 2e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME81591.1 - 2.3e-08 33.5 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME81591.1 - 6.1e-06 26.1 0.0 9.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EME81591.1 - 1.2e-05 24.5 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EME81591.1 - 4.2e-05 23.0 0.3 0.00058 19.3 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EME81591.1 - 0.037 13.9 0.1 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Elf1 PF05129.8 EME81592.1 - 7.5e-24 83.2 2.0 9.2e-24 82.9 1.4 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 EME81592.1 - 0.068 12.7 0.9 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.2 EME81592.1 - 0.13 12.0 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 EME81592.1 - 0.46 10.3 2.8 0.46 10.3 0.9 1.8 1 1 1 2 2 2 0 Ribosomal L37ae protein family zf-C2H2_6 PF13912.1 EME81592.1 - 5.2 7.1 6.8 0.2 11.6 0.8 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_CH_N PF12471.3 EME81593.1 - 1.5e-91 305.3 0.0 2.3e-91 304.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EME81593.1 - 2.4e-17 62.6 0.0 3.9e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Fucose_iso_N1 PF07881.7 EME81593.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain Myb_DNA-binding PF00249.26 EME81594.1 - 3e-06 27.1 0.0 6.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.6 EME81595.1 - 1.5e-26 92.1 7.8 1.5e-26 92.1 5.4 6.6 5 1 2 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EME81595.1 - 6.4e-09 35.6 9.7 1.1e-08 34.9 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME81595.1 - 1.8e-08 33.8 6.4 3.1e-08 33.1 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME81595.1 - 3.2e-08 33.0 9.2 6e-08 32.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME81595.1 - 5.4e-08 32.5 6.9 1e-07 31.6 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME81595.1 - 2.2e-06 27.3 9.1 3.8e-06 26.5 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME81595.1 - 6.6e-06 25.7 6.3 1.7e-05 24.4 4.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME81595.1 - 3.5e-05 23.6 8.1 6.4e-05 22.7 5.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EME81595.1 - 0.00018 21.5 1.9 0.0011 19.0 1.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger TerY-C PF15616.1 EME81595.1 - 0.00057 19.8 3.2 0.0034 17.3 2.2 2.4 1 0 0 1 1 1 1 TerY-C metal binding domain zinc-ribbons_6 PF07191.7 EME81595.1 - 0.0077 16.0 4.8 0.027 14.2 2.1 2.6 1 1 1 2 2 2 1 zinc-ribbons zf-RING_6 PF14835.1 EME81595.1 - 0.0079 15.9 4.5 0.016 15.0 3.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EME81595.1 - 0.047 13.2 6.0 0.14 11.7 4.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4250 PF14056.1 EME81595.1 - 0.19 11.4 3.4 5.7 6.7 0.1 4.1 4 0 0 4 4 3 0 Domain of unknown function (DUF4250) FYVE PF01363.16 EME81595.1 - 1.3 8.9 7.5 8 6.4 4.9 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.3 EME81595.1 - 1.7 8.2 7.9 0.23 10.9 2.4 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Di19 PF05605.7 EME81595.1 - 1.9 8.6 6.9 5.4 7.2 3.4 2.6 2 1 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.1 EME81595.1 - 9.6 5.8 6.6 39 3.8 4.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2H2 PF00096.21 EME81596.1 - 3e-07 30.3 6.7 0.0013 18.9 0.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-BED PF02892.10 EME81596.1 - 5.8e-05 22.7 6.6 0.0028 17.3 0.0 3.1 3 0 0 3 3 3 2 BED zinc finger zf-C2H2_4 PF13894.1 EME81596.1 - 0.0051 17.0 10.2 0.14 12.5 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME81596.1 - 0.02 15.1 4.6 0.58 10.5 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 EME81596.1 - 6 7.0 6.3 14 5.8 0.1 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) EMP24_GP25L PF01105.19 EME81597.1 - 5.5e-47 159.8 0.2 6.2e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2606 PF10794.4 EME81597.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) EthD PF07110.6 EME81598.1 - 1.8e-18 67.2 1.2 2.3e-18 66.9 0.8 1.2 1 0 0 1 1 1 1 EthD domain Glyco_transf_90 PF05686.7 EME81599.1 - 8e-27 93.9 0.8 1.1e-26 93.5 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EME81599.1 - 0.0087 16.3 0.3 0.024 14.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pmp3 PF01679.12 EME81601.1 - 7.6e-22 76.7 10.4 1.1e-21 76.2 7.2 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BCDHK_Adom3 PF10436.4 EME81602.1 - 1.1e-40 138.7 0.3 1.8e-40 138.1 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EME81602.1 - 9.5e-12 44.6 0.0 3.9e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME81602.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EME81602.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 EME81603.1 - 4.2e-70 235.8 0.2 1.1e-67 227.8 0.0 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EME81603.1 - 5.3e-59 199.2 1.4 1e-58 198.3 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EME81603.1 - 2.3e-52 177.7 0.9 4.1e-52 176.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME81603.1 - 2e-26 93.1 0.0 3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EME81603.1 - 1.9e-07 31.3 0.2 1.1e-06 28.9 0.0 2.4 2 1 0 2 2 2 1 MATH domain SUKH_6 PF14568.1 EME81603.1 - 0.0043 17.5 0.2 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall zf-H2C2_2 PF13465.1 EME81604.1 - 8.7e-19 66.8 25.3 8.1e-09 35.3 0.9 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EME81604.1 - 1.5e-17 62.7 22.8 0.00028 21.0 0.3 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME81604.1 - 3e-11 42.8 20.3 0.0027 17.9 0.4 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EME81604.1 - 0.0051 16.9 10.3 0.44 10.8 0.2 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME81604.1 - 0.72 10.0 4.5 4.9 7.4 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EME81604.1 - 2.8 7.9 9.5 15 5.6 0.1 4.1 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EME81604.1 - 4.1 7.4 15.0 0.23 11.4 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger FYVE PF01363.16 EME81604.1 - 7.8 6.4 8.3 1.3 8.9 2.5 2.1 2 1 0 2 2 2 0 FYVE zinc finger HET PF06985.6 EME81605.1 - 4e-28 98.3 1.3 7.5e-28 97.4 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3954 PF13128.1 EME81606.1 - 0.034 13.5 0.1 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) Zn_clus PF00172.13 EME81606.1 - 0.27 11.1 5.9 0.05 13.5 1.5 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Erf4 PF10256.4 EME81608.1 - 7.8e-31 106.3 0.0 9.9e-31 106.0 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ORC6 PF05460.8 EME81609.1 - 8.3e-36 123.8 11.5 1.7e-29 103.0 5.8 2.2 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.27 EME81610.1 - 4e-73 238.9 11.6 1.7e-11 43.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EME81610.1 - 3.7e-24 84.7 9.3 6e-24 84.0 6.5 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EME81610.1 - 2e-07 29.6 0.2 2e-05 23.0 0.1 2.7 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EME81610.1 - 9.9e-06 24.5 0.2 0.018 13.8 0.0 3.2 1 1 1 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 EME81610.1 - 7.2e-05 21.1 0.5 0.11 10.5 0.0 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MMS1_N PF10433.4 EME81610.1 - 0.042 12.0 0.0 5.4 5.0 0.0 2.7 1 1 1 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.1 EME81610.1 - 0.1 11.7 0.1 16 4.4 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EME81610.1 - 0.13 11.9 0.8 17 5.1 0.0 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Atg14 PF10186.4 EME81610.1 - 7.6 5.3 7.1 12 4.7 4.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SAGA-Tad1 PF12767.2 EME81611.1 - 0.065 12.8 1.0 0.11 12.1 0.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1183 PF06682.7 EME81613.1 - 1.8e-89 300.4 14.8 4.1e-89 299.3 10.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) PAP2 PF01569.16 EME81613.1 - 0.11 12.1 2.9 4.8 6.8 0.4 2.9 3 0 0 3 3 3 0 PAP2 superfamily Herpes_LMP2 PF07415.6 EME81613.1 - 0.57 8.7 2.8 0.51 8.8 1.3 1.4 1 1 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Kin17_mid PF10357.4 EME81614.1 - 1.7e-47 160.2 1.0 1.7e-47 160.2 0.7 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EME81614.1 - 7.4e-07 29.1 1.4 1.7e-06 28.0 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME81614.1 - 3.3e-05 23.9 2.0 6.4e-05 23.0 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EME81614.1 - 0.00035 20.6 3.7 0.0014 18.6 0.2 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EME81614.1 - 0.041 14.2 0.9 0.1 12.9 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger TFIID_90kDa PF04494.10 EME81614.1 - 0.058 13.4 0.8 0.19 11.7 0.4 1.9 1 1 1 2 2 2 0 WD40 associated region in TFIID subunit DUF3571 PF12095.3 EME81614.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) zf-C2H2 PF00096.21 EME81614.1 - 0.19 12.1 0.9 0.57 10.6 0.6 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Defensin_propep PF00879.13 EME81614.1 - 0.21 11.6 0.7 0.58 10.1 0.5 1.7 1 0 0 1 1 1 0 Defensin propeptide PAN_1 PF00024.21 EME81616.1 - 9.9e-05 22.0 18.7 0.077 12.7 1.6 4.3 4 1 0 4 4 4 3 PAN domain PAN_3 PF08277.7 EME81616.1 - 0.53 9.9 19.1 0.2 11.2 1.1 3.8 4 0 0 4 4 4 0 PAN-like domain ABC_membrane PF00664.18 EME81617.1 - 1.9e-97 325.9 38.5 8.1e-50 169.7 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME81617.1 - 3.1e-68 228.3 0.0 2.9e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME81617.1 - 1.3e-14 53.9 0.0 7.4e-05 22.0 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME81617.1 - 1.7e-09 38.0 0.0 1.1 9.1 0.0 4.3 3 1 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EME81617.1 - 5.4e-09 35.4 0.5 0.0005 19.5 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EME81617.1 - 1.5e-07 30.3 3.6 0.0045 15.6 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EME81617.1 - 4.7e-07 29.1 0.1 0.12 11.5 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME81617.1 - 8e-07 29.2 2.1 0.0065 16.4 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EME81617.1 - 4.3e-06 27.5 0.4 0.13 13.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EME81617.1 - 5.3e-05 23.3 1.8 0.37 10.9 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME81617.1 - 7.7e-05 22.1 0.1 0.42 9.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EME81617.1 - 0.00031 20.5 2.7 0.37 10.7 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EME81617.1 - 0.00053 20.1 2.3 7.3 6.7 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EME81617.1 - 0.0012 18.6 0.0 1.8 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EME81617.1 - 0.0026 17.7 0.2 0.56 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EME81617.1 - 0.0038 16.1 0.1 1.2 8.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.12 EME81617.1 - 0.0051 16.6 0.2 2.9 7.6 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EME81617.1 - 0.012 15.9 0.0 7.6 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EME81617.1 - 0.013 14.1 0.0 1.3 7.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 EME81617.1 - 0.014 15.0 0.3 10 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EME81617.1 - 0.015 15.1 1.8 4 7.3 0.0 4.3 4 1 1 5 5 5 0 AAA domain ATP-synt_ab PF00006.20 EME81617.1 - 0.018 14.5 0.9 5.4 6.4 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EME81617.1 - 0.026 14.2 1.0 3.1 7.6 0.2 3.2 2 0 0 2 2 2 0 Part of AAA domain MobB PF03205.9 EME81617.1 - 0.039 13.6 0.2 5.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EME81617.1 - 0.042 13.2 3.9 12 5.1 0.2 3.9 4 0 0 4 4 4 0 AAA-like domain AAA_30 PF13604.1 EME81617.1 - 0.049 13.2 8.3 2.2 7.8 0.0 4.2 5 0 0 5 5 4 0 AAA domain APS_kinase PF01583.15 EME81617.1 - 0.056 13.0 0.3 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EME81617.1 - 0.081 13.1 0.5 8.8 6.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_23 PF13476.1 EME81617.1 - 0.099 12.9 0.3 6 7.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 EME81617.1 - 0.12 12.8 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EME81617.1 - 0.31 11.0 2.4 8.9 6.2 0.1 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase Cation_efflux PF01545.16 EME81619.1 - 9.2e-36 123.3 11.7 1.1e-35 123.0 8.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3624 PF12292.3 EME81619.1 - 1.1 9.7 5.6 0.43 11.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) UDPG_MGDP_dh PF00984.14 EME81620.1 - 2.5e-21 75.6 0.0 7.8e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.9 EME81620.1 - 6.9e-16 58.1 0.1 2.4e-13 49.8 0.0 2.9 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EME81620.1 - 1.1e-05 25.4 0.0 2.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Mg_chelatase PF01078.16 EME81620.1 - 0.076 12.1 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ScdA_N PF04405.9 EME81620.1 - 0.13 11.6 0.4 0.35 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) Chitin_synth_2 PF03142.10 EME81621.1 - 3.5e-31 108.1 0.0 4.7e-25 87.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EME81621.1 - 1.7e-09 37.7 0.0 3.7e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME81621.1 - 4.7e-07 29.7 2.0 9.8e-07 28.6 1.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EME81621.1 - 0.00015 21.4 0.0 0.0095 15.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EME81622.1 - 5.9e-18 64.7 0.3 4.9e-17 61.7 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EME81622.1 - 1.1e-16 61.4 0.0 1.5e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EME81622.1 - 1e-06 28.5 0.0 1.7e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 LURAP PF14854.1 EME81623.1 - 0.03 14.0 3.9 0.051 13.2 1.0 2.7 1 1 0 1 1 1 0 Leucine rich adaptor protein Filament PF00038.16 EME81623.1 - 1.6 8.0 66.1 2.7 7.3 20.9 3.0 1 1 2 3 3 3 0 Intermediate filament protein Nop10p PF04135.7 EME81625.1 - 1.1e-22 79.5 0.2 1.2e-22 79.3 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family SRP54 PF00448.17 EME81627.1 - 1.1e-76 256.6 1.8 2.9e-76 255.3 0.6 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EME81627.1 - 2.5e-25 88.7 6.0 2.5e-25 88.7 4.2 4.9 2 1 3 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 EME81627.1 - 8.6e-14 51.3 1.2 1.3e-13 50.8 0.2 1.8 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EME81627.1 - 4.2e-09 36.0 0.0 1.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EME81627.1 - 3.8e-07 30.0 0.1 7.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EME81627.1 - 4.9e-06 26.3 0.1 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EME81627.1 - 1.1e-05 24.9 0.2 5e-05 22.8 0.1 2.2 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EME81627.1 - 0.00034 20.7 0.1 0.0011 19.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EME81627.1 - 0.00059 20.6 0.0 0.002 18.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.1 EME81627.1 - 0.00068 19.6 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EME81627.1 - 0.0018 17.9 0.0 0.0048 16.5 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EME81627.1 - 0.0021 17.4 0.5 0.0073 15.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.7 EME81627.1 - 0.0042 16.2 0.0 0.009 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin 6PF2K PF01591.13 EME81627.1 - 0.0059 15.7 0.1 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TrwB_AAD_bind PF10412.4 EME81627.1 - 0.014 14.0 0.0 0.04 12.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EME81627.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Spectrin PF00435.16 EME81627.1 - 0.015 15.5 1.9 0.12 12.6 0.2 2.5 2 0 0 2 2 2 0 Spectrin repeat ATP_bind_1 PF03029.12 EME81627.1 - 0.033 13.7 0.0 0.099 12.1 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EME81627.1 - 0.041 14.1 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME81627.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PTPlike_phytase PF14566.1 EME81627.1 - 0.055 13.5 0.4 1.7 8.6 0.0 3.1 4 0 0 4 4 3 0 Inositol hexakisphosphate AAA_16 PF13191.1 EME81627.1 - 0.057 13.3 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EME81627.1 - 0.065 12.4 1.0 5.4 6.1 0.8 3.1 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.1 EME81627.1 - 0.074 12.8 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain BDV_P40 PF06407.6 EME81627.1 - 0.18 10.6 2.8 0.36 9.6 1.9 1.5 1 0 0 1 1 1 0 Borna disease virus P40 protein Rrp15p PF07890.7 EME81628.1 - 1.5e-35 122.0 11.3 1.5e-35 122.0 7.9 2.2 2 1 0 2 2 2 1 Rrp15p NMT1 PF09084.6 EME81630.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EME81630.1 - 0.014 14.6 0.0 0.045 12.9 0.0 1.8 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 HET PF06985.6 EME81631.1 - 6.7e-15 55.4 0.4 6.7e-15 55.4 0.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 EME81632.1 - 1.4e-14 53.6 0.1 2.3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81632.1 - 3.5e-09 36.4 11.6 6.2e-09 35.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 EME81633.1 - 0.0065 16.1 0.1 0.0071 16.0 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.11 EME81634.1 - 2.4e-12 46.2 18.4 2.4e-12 46.2 12.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME81634.1 - 1e-07 30.8 0.8 1e-07 30.8 0.6 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter DUF1510 PF07423.6 EME81634.1 - 0.0098 15.2 0.1 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Nuc_N PF14448.1 EME81635.1 - 0.14 11.7 0.9 7.7 6.1 0.0 3.4 3 0 0 3 3 3 0 Nuclease N terminal IF4E PF01652.13 EME81636.1 - 6.3e-54 181.9 0.1 1.1e-53 181.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 EME81637.1 - 1.3e-24 87.0 0.0 2.5e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pol_alpha_B_N PF08418.5 EME81637.1 - 1.7 8.1 9.8 0.56 9.6 4.5 1.8 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal AIG2 PF06094.7 EME81638.1 - 2.2e-15 56.9 0.0 3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family PQ-loop PF04193.9 EME81639.1 - 1.6e-23 81.9 0.4 1.9e-13 49.7 0.1 2.4 2 0 0 2 2 2 2 PQ loop repeat Pho88 PF10032.4 EME81639.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) DUF2626 PF11117.3 EME81639.1 - 3.8 7.9 7.4 1.2 9.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2626) zf-C2H2 PF00096.21 EME81640.1 - 3e-08 33.5 8.6 1.9e-05 24.7 0.6 3.8 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME81640.1 - 2.2e-06 27.6 10.6 0.00019 21.5 1.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.13 EME81640.1 - 2.8e-06 27.1 13.8 2.8e-06 27.1 9.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EME81640.1 - 0.00073 19.6 7.0 0.015 15.5 0.4 4.9 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EME81640.1 - 0.014 15.2 8.8 0.72 9.8 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME81640.1 - 0.09 12.9 4.5 6.6 7.0 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EME81640.1 - 0.1 12.7 2.4 0.24 11.5 1.7 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EME81640.1 - 0.17 12.1 6.3 0.44 10.8 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PhoD PF09423.5 EME81641.1 - 2.4e-63 214.3 0.0 3.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Cna_B PF05738.8 EME81641.1 - 0.042 13.6 0.4 0.086 12.6 0.2 1.5 1 0 0 1 1 1 0 Cna protein B-type domain GFA PF04828.9 EME81642.1 - 2.1e-07 30.7 1.2 2.1e-07 30.7 0.8 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EME81642.1 - 0.45 9.7 0.1 0.45 9.7 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-Dof PF02701.10 EME81642.1 - 1.1 9.2 4.2 1.9 8.4 0.4 2.2 1 1 1 2 2 2 0 Dof domain, zinc finger Peptidase_M18 PF02127.10 EME81643.1 - 1.1e-124 416.2 0.0 1.3e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Self-incomp_S1 PF05938.6 EME81643.1 - 0.0065 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Plant self-incompatibility protein S1 Pyr_redox_2 PF07992.9 EME81644.1 - 4.2e-13 49.6 0.0 7.9e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME81644.1 - 4.3e-05 23.6 0.2 0.056 13.5 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME81644.1 - 0.00034 19.2 0.2 0.00071 18.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EME81644.1 - 0.00037 19.4 0.1 0.0009 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EME81644.1 - 0.0014 17.6 0.1 0.021 13.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EME81644.1 - 0.0014 17.6 0.2 0.0065 15.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME81644.1 - 0.0016 18.2 0.2 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EME81644.1 - 0.0037 16.2 0.5 0.011 14.6 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME81644.1 - 0.007 16.3 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME81644.1 - 0.011 14.6 0.2 0.081 11.8 0.1 2.0 1 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EME81644.1 - 0.076 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EME81645.1 - 1.5e-29 103.0 0.2 2.6e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME81645.1 - 9.7e-20 71.3 0.0 1.3e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME81645.1 - 4.9e-10 39.3 0.0 7.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME81645.1 - 0.00012 22.2 0.9 0.00043 20.3 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EME81645.1 - 0.00026 20.5 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME81645.1 - 0.0025 17.1 0.3 0.014 14.6 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family CpcD PF01383.16 EME81645.1 - 0.14 12.3 0.4 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain Pep3_Vps18 PF05131.9 EME81646.1 - 7.7e-43 145.4 0.1 2e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EME81646.1 - 3.5e-13 49.3 5.8 2.4e-10 40.1 0.5 3.6 3 1 1 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EME81646.1 - 0.00094 18.9 0.4 0.0025 17.6 0.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME81646.1 - 0.0018 17.9 0.2 0.0041 16.8 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF1664 PF07889.7 EME81646.1 - 0.011 15.5 2.1 0.048 13.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vps39_2 PF10367.4 EME81646.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.2 EME81646.1 - 0.13 12.4 0.3 0.35 11.0 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_19 PF14559.1 EME81646.1 - 1.7 9.0 6.6 0.69 10.2 0.3 3.5 4 1 1 5 5 5 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EME81646.1 - 1.7 8.3 3.9 0.43 10.2 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.1 EME81648.1 - 1.1e-16 60.7 0.3 1.7e-07 31.5 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME81648.1 - 8e-16 58.1 0.1 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME81648.1 - 1.6e-15 56.0 1.0 4.2e-10 38.9 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EME81648.1 - 5.9e-12 44.5 0.1 4.9e-07 29.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EME81648.1 - 5.9e-09 35.8 0.2 7.4e-08 32.4 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) TMEM52 PF14979.1 EME81648.1 - 0.06 13.2 0.1 1.2 9.0 0.2 2.0 1 1 1 2 2 2 0 Transmembrane 52 SKIP_SNW PF02731.10 EME81650.1 - 7.5e-66 220.4 7.4 7.5e-66 220.4 5.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain UPF0029 PF01205.14 EME81651.1 - 1.1e-31 108.6 0.0 2.3e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EME81651.1 - 1.5e-08 34.4 0.0 3.5e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 RWD domain XRN_N PF03159.13 EME81653.1 - 2.7e-101 337.9 0.0 4.6e-101 337.1 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus R3H PF01424.17 EME81653.1 - 0.0099 15.5 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain WD40 PF00400.27 EME81654.1 - 1.9e-41 138.5 6.3 8.7e-08 31.7 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EME81654.1 - 2.4e-25 88.2 0.1 5.5e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3312 PF11768.3 EME81654.1 - 0.018 13.3 0.0 0.06 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) F-box PF00646.28 EME81655.1 - 6.2e-05 22.5 0.2 0.00017 21.1 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME81655.1 - 0.044 13.5 2.3 0.13 11.9 1.6 1.8 1 0 0 1 1 1 0 F-box-like Epimerase PF01370.16 EME81657.1 - 1.2e-10 41.2 0.2 5.5e-10 39.0 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME81657.1 - 1e-09 38.6 0.1 6.1e-09 36.1 0.1 2.2 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EME81657.1 - 5.6e-07 29.0 0.0 9.3e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EME81657.1 - 7.9e-07 28.0 0.0 2.6e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EME81657.1 - 0.005 16.5 0.1 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME81657.1 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 EME81657.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.11 EME81657.1 - 0.023 14.1 0.1 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EME81657.1 - 0.044 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EME81657.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain F-box-like PF12937.2 EME81658.1 - 0.049 13.3 1.6 0.46 10.2 0.0 2.7 2 0 0 2 2 2 0 F-box-like DHDPS PF00701.17 EME81658.1 - 0.062 11.8 0.1 0.095 11.2 0.1 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family F-box-like_2 PF13013.1 EME81658.1 - 0.063 12.9 0.4 1.7 8.3 0.0 2.6 2 1 0 2 2 2 0 F-box-like domain F-box PF00646.28 EME81658.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain YlbD_coat PF14071.1 EME81658.1 - 0.21 11.6 0.8 18 5.4 0.1 2.3 2 0 0 2 2 2 0 Putative coat protein MFS_1 PF07690.11 EME81659.1 - 7.5e-09 34.7 5.5 9.8e-09 34.3 3.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME81659.1 - 0.0002 20.1 1.2 0.00021 19.9 0.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3040 PF11239.3 EME81659.1 - 0.26 11.3 1.0 0.39 10.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) FAD-oxidase_C PF02913.14 EME81660.1 - 5.2e-49 166.8 0.0 9.4e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EME81660.1 - 4.7e-37 126.5 0.4 1.9e-36 124.6 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Proteasome PF00227.21 EME81661.1 - 9.7e-50 168.4 0.3 1.3e-49 168.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME81661.1 - 2.8e-13 48.8 0.1 2.8e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 EME81661.1 - 0.07 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) ThiF PF00899.16 EME81663.1 - 7.8e-16 58.1 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family MFS_1 PF07690.11 EME81664.1 - 1.5e-41 142.2 54.5 5.8e-40 137.0 35.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME81664.1 - 6.8e-11 41.0 28.0 1.5e-10 39.9 19.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EME81664.1 - 1.7e-09 36.8 12.1 1.7e-09 36.8 8.4 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter Pho88 PF10032.4 EME81666.1 - 1.8e-84 281.7 0.2 2e-84 281.6 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Adenylsucc_synt PF00709.16 EME81667.1 - 2.1e-158 527.3 0.2 2.4e-158 527.2 0.2 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1281 PF06924.6 EME81667.1 - 0.051 12.9 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Peptidase_C78 PF07910.8 EME81668.1 - 2.6e-46 157.4 0.0 4.3e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EME81668.1 - 0.04 14.0 0.9 0.04 14.0 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sugar_tr PF00083.19 EME81669.1 - 1.2e-124 416.3 28.8 1.4e-124 416.1 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME81669.1 - 3e-20 72.2 26.8 3e-20 72.2 18.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2427 PF10348.4 EME81669.1 - 0.12 11.9 3.4 0.22 11.0 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Helicase_C_3 PF13625.1 EME81670.1 - 4.9e-26 91.0 0.0 1.3e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME81670.1 - 1.7e-14 54.0 1.0 5.1e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME81670.1 - 1.5e-12 46.9 0.1 2.6e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME81670.1 - 3.8e-09 36.2 0.0 1.2e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME81670.1 - 3.3e-08 33.2 0.0 7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EME81670.1 - 0.0059 15.4 0.1 0.011 14.5 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF2381 PF09544.5 EME81671.1 - 0.073 12.1 0.8 0.083 11.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DivIC PF04977.10 EME81671.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Rick_17kDa_Anti PF05433.10 EME81672.1 - 0.0011 18.5 8.4 0.0019 17.8 5.8 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EME81672.1 - 0.0071 15.9 3.8 0.013 15.1 2.7 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 EME81672.1 - 0.014 15.0 2.1 0.033 13.8 1.5 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF533 PF04391.7 EME81672.1 - 0.027 13.8 0.9 0.044 13.1 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) ATPase_gene1 PF09527.5 EME81672.1 - 0.11 12.2 3.0 0.16 11.8 2.1 1.1 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) SAD_SRA PF02182.12 EME81673.1 - 9.5e-05 21.7 0.3 0.00019 20.7 0.2 1.5 1 0 0 1 1 1 1 SAD/SRA domain CoatB PF10389.4 EME81674.1 - 0.66 9.8 4.6 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B Dynamin_M PF01031.15 EME81675.1 - 1.1e-104 349.4 0.7 1.5e-104 348.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EME81675.1 - 1.3e-56 190.9 0.4 2.5e-56 190.0 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EME81675.1 - 2.7e-29 100.8 7.7 5.9e-29 99.8 5.3 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EME81675.1 - 0.00011 22.0 0.2 0.0014 18.6 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME81675.1 - 0.038 14.4 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EME81675.1 - 0.05 12.8 0.2 17 4.6 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP-synt_ab PF00006.20 EME81676.1 - 4.4e-115 382.6 0.0 6.3e-115 382.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME81676.1 - 2.6e-20 72.9 0.5 7.4e-20 71.5 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EME81676.1 - 1.9e-13 50.4 2.4 4.3e-13 49.2 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M23 PF01551.17 EME81676.1 - 0.081 12.9 0.1 5.8 7.0 0.0 3.3 3 0 0 3 3 3 0 Peptidase family M23 DUF763 PF05559.6 EME81676.1 - 0.15 11.0 0.7 0.43 9.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF763) tRNA-synt_1b PF00579.20 EME81677.1 - 1.1e-70 238.0 0.0 1.4e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Methyltransf_23 PF13489.1 EME81678.1 - 6.2e-17 61.7 0.0 9.6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME81678.1 - 1.3e-09 38.3 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME81678.1 - 2.3e-09 37.8 0.0 3e-08 34.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME81678.1 - 2.7e-09 37.4 0.0 3.2e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME81678.1 - 6.9e-09 35.4 0.0 4.9e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME81678.1 - 2.8e-05 24.2 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EME81678.1 - 3e-05 24.3 0.0 0.00011 22.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME81678.1 - 4.6e-05 22.5 0.0 0.00038 19.5 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EME81678.1 - 0.00012 21.3 0.0 0.00088 18.4 0.0 2.2 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EME81678.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME81678.1 - 0.0014 18.0 0.0 0.0038 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME81678.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain 4HBT PF03061.17 EME81679.1 - 7.3e-05 22.8 0.1 0.0002 21.4 0.1 1.7 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME81679.1 - 0.083 12.6 0.1 0.92 9.2 0.0 2.1 2 1 0 2 2 2 0 Thioesterase-like superfamily AA_permease_2 PF13520.1 EME81680.1 - 5.4e-42 143.8 39.6 3.6e-41 141.0 27.4 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME81680.1 - 4.9e-24 84.5 32.0 6.9e-24 84.0 22.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 EME81680.1 - 0.5 10.2 0.0 0.5 10.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3493) DUF3353 PF11833.3 EME81680.1 - 2.2 7.7 6.6 0.53 9.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) DER1 PF04511.10 EME81681.1 - 2.7e-49 167.3 4.2 3e-49 167.1 2.9 1.0 1 0 0 1 1 1 1 Der1-like family PAP2 PF01569.16 EME81681.1 - 0.052 13.2 4.6 0.13 11.9 3.2 1.8 1 1 0 1 1 1 0 PAP2 superfamily Histone PF00125.19 EME81682.1 - 2.8e-29 101.0 0.1 3.6e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME81682.1 - 4.9e-05 23.4 0.0 6.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EME81682.1 - 0.0037 17.2 0.3 0.0059 16.6 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EME81682.1 - 0.021 14.1 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EME81682.1 - 0.078 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MBOAT PF03062.14 EME81683.1 - 9.3e-44 149.8 5.1 9.3e-44 149.8 3.5 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Methyltransf_23 PF13489.1 EME81684.1 - 5.7e-12 45.6 0.0 8.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME81684.1 - 8.6e-08 31.9 0.0 1.6e-06 27.7 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME81684.1 - 1.7e-07 31.6 0.0 9.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME81684.1 - 5.8e-05 23.5 0.0 0.00019 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME81684.1 - 0.00013 21.1 0.0 0.00026 20.1 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EME81684.1 - 0.0048 16.2 0.0 0.0087 15.3 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.1 EME81684.1 - 0.011 16.1 0.0 0.074 13.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME81684.1 - 0.012 16.2 0.0 0.23 12.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EME81684.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ribosomal_L4 PF00573.17 EME81685.1 - 3.8e-41 140.5 0.4 5.2e-41 140.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EME81685.1 - 4.2e-25 87.4 0.4 4.2e-25 87.4 0.3 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain NmrA PF05368.8 EME81687.1 - 4.3e-10 39.2 0.0 6.2e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME81687.1 - 3.5e-07 30.4 0.0 6.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME81687.1 - 0.003 16.2 0.0 0.0051 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME81687.1 - 0.049 13.0 0.0 0.24 10.7 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HSP70 PF00012.15 EME81690.1 - 0.0039 15.1 0.1 0.0055 14.6 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein HipA_N PF07805.7 EME81691.1 - 0.013 15.7 0.0 0.1 12.8 0.0 2.3 1 1 0 1 1 1 0 HipA-like N-terminal domain Ribosomal_L34 PF00468.12 EME81691.1 - 0.043 13.4 0.3 0.1 12.2 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein L34 TPR_11 PF13414.1 EME81693.1 - 1.5e-27 95.0 23.9 3.9e-07 29.6 0.1 10.6 8 2 3 11 11 11 6 TPR repeat TPR_2 PF07719.12 EME81693.1 - 2.8e-22 76.7 30.1 0.00023 20.8 0.0 11.6 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 EME81693.1 - 2.2e-20 72.3 22.0 2.5e-06 27.3 0.7 8.2 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EME81693.1 - 1e-19 69.2 20.4 0.0014 18.1 0.0 9.9 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME81693.1 - 2.1e-19 69.6 24.9 0.014 15.7 0.1 10.9 6 2 3 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EME81693.1 - 3.7e-17 60.7 18.5 0.00062 19.3 0.0 10.7 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME81693.1 - 5.4e-16 57.6 21.9 0.0075 16.8 0.0 12.3 9 3 3 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 EME81693.1 - 6.3e-13 49.0 22.0 0.03 14.9 1.4 10.0 10 2 2 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME81693.1 - 1.8e-10 40.1 18.1 0.66 10.3 0.1 11.9 13 1 1 14 14 14 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME81693.1 - 4.7e-09 35.3 26.7 0.066 13.0 0.0 9.5 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 EME81693.1 - 2.2e-06 27.7 25.3 0.0026 18.0 0.0 11.2 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME81693.1 - 0.0044 16.9 20.2 2.8 8.0 0.2 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EME81693.1 - 0.01 15.9 16.6 0.81 9.8 0.0 6.8 6 3 2 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 MIP-T3 PF10243.4 EME81693.1 - 3.4 6.0 52.4 7 4.9 36.3 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ALIX_LYPXL_bnd PF13949.1 EME81694.1 - 0.00086 18.3 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Sec8_exocyst PF04048.9 EME81695.1 - 9.4e-44 148.4 3.2 1.6e-43 147.7 0.9 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EME81695.1 - 7.7e-10 38.1 2.7 2.1e-09 36.7 1.9 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Ded_cyto PF06920.8 EME81695.1 - 0.15 11.3 2.8 0.31 10.3 0.4 2.4 1 1 1 2 2 2 0 Dedicator of cytokinesis HsbA PF12296.3 EME81697.1 - 1.6e-16 60.2 11.5 3.7e-16 59.0 6.4 2.0 2 0 0 2 2 2 1 Hydrophobic surface binding protein A TRI12 PF06609.8 EME81698.1 - 4.3e-31 107.7 25.2 5.2e-31 107.4 17.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME81698.1 - 1.8e-20 72.9 46.2 3.6e-20 71.9 29.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MipA PF06629.7 EME81698.1 - 0.083 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 MltA-interacting protein MipA DEAD PF00270.24 EME81700.1 - 3.4e-40 137.3 0.1 6.4e-40 136.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME81700.1 - 1.7e-28 98.2 0.1 3.9e-28 97.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EME81700.1 - 0.0007 19.3 0.2 0.0016 18.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EME81700.1 - 0.014 15.0 0.3 0.034 13.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EME81700.1 - 0.022 14.4 0.1 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.10 EME81700.1 - 0.028 14.2 0.1 0.054 13.3 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EME81700.1 - 0.084 12.4 0.2 0.19 11.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EME81700.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 EME81700.1 - 0.14 12.2 0.7 0.63 10.1 0.5 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EME81701.1 - 6.1e-69 231.4 1.9 1.4e-68 230.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EME81701.1 - 1.2e-09 37.5 0.4 2.6e-09 36.4 0.3 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EME81701.1 - 7.1e-09 35.5 2.1 6.3e-07 29.3 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME81701.1 - 1.9e-07 31.0 4.7 2.9e-06 27.2 1.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME81701.1 - 0.00019 21.5 0.7 0.0041 17.2 0.2 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 EME81701.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EME81701.1 - 0.18 12.2 3.7 1.4 9.4 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-DBF PF07535.7 EME81701.1 - 0.34 10.6 4.7 0.15 11.8 0.6 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.1 EME81701.1 - 1.7 9.1 3.7 16 6.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FAD_binding_8 PF08022.7 EME81702.1 - 1.9e-21 75.9 0.0 3.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME81702.1 - 1.6e-15 57.3 0.0 4.2e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME81702.1 - 3e-08 33.8 7.4 3e-08 33.8 5.1 2.0 1 1 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_5 PF13202.1 EME81702.1 - 2.2e-05 23.5 1.7 5.4e-05 22.3 1.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 EME81702.1 - 2.4e-05 23.3 1.2 5.6e-05 22.1 0.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EME81702.1 - 7.4e-05 22.3 0.8 0.00022 20.8 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EME81702.1 - 7.8e-05 22.7 0.5 0.0003 20.8 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EME81702.1 - 0.0011 18.4 0.4 0.003 17.1 0.2 1.7 2 0 0 2 2 2 1 EF-hand domain pair FAD_binding_6 PF00970.19 EME81702.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Yip1 PF04893.12 EME81702.1 - 0.83 9.1 15.3 1.8 8.0 10.6 1.5 1 1 0 1 1 1 0 Yip1 domain Amidohydro_2 PF04909.9 EME81703.1 - 1.4e-39 136.3 0.0 1.7e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF3840 PF12944.2 EME81703.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) Bac_rhodopsin PF01036.13 EME81704.1 - 4.2e-53 179.9 14.3 5.3e-53 179.6 9.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Phage_XkdX PF09693.5 EME81704.1 - 0.12 11.8 0.3 0.12 11.8 0.2 2.5 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Transp_cyt_pur PF02133.10 EME81705.1 - 2.3e-20 72.5 37.9 5.2e-20 71.4 26.3 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CAF1A PF12253.3 EME81707.1 - 1.1e-20 73.4 8.7 1.1e-20 73.4 6.0 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EME81707.1 - 0.028 13.8 62.6 0.026 13.9 42.4 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 EME81707.1 - 1.7 7.1 5.6 2.2 6.7 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 EME81707.1 - 3.3 5.8 35.2 6.2 4.9 24.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TP6A_N PF04406.9 EME81708.1 - 9.6e-18 63.6 0.1 2.7e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DIOX_N PF14226.1 EME81709.1 - 3.4e-26 92.0 0.0 6.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME81709.1 - 1.2e-20 73.6 0.0 2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hydrophobin_2 PF06766.6 EME81711.1 - 4.5e-18 64.6 5.3 5.9e-18 64.3 3.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Peptidase_S10 PF00450.17 EME81712.1 - 1.5e-89 301.0 0.0 2.2e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.16 EME81712.1 - 0.0036 16.5 0.0 0.094 11.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Filament PF00038.16 EME81713.1 - 5.5e-09 35.9 115.6 0.0017 17.9 28.7 5.3 1 1 3 4 4 4 3 Intermediate filament protein Myosin_tail_1 PF01576.14 EME81713.1 - 8.4e-05 20.5 136.7 0.011 13.4 49.6 3.8 1 1 2 3 3 3 2 Myosin tail GAS PF13851.1 EME81713.1 - 0.00055 19.1 126.7 0.036 13.2 12.1 6.5 2 1 4 6 6 6 5 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EME81713.1 - 0.0021 16.7 12.3 0.0021 16.7 8.5 6.4 1 1 6 7 7 7 2 Spc7 kinetochore protein WEMBL PF05701.6 EME81713.1 - 0.0054 15.2 157.5 0.32 9.3 35.1 4.7 1 1 3 4 4 4 3 Weak chloroplast movement under blue light IncA PF04156.9 EME81713.1 - 0.0083 15.7 11.6 0.0083 15.7 8.1 6.9 3 1 3 6 6 6 3 IncA protein Tropomyosin_1 PF12718.2 EME81713.1 - 0.0091 15.8 22.5 0.0091 15.8 15.6 6.3 1 1 4 6 6 5 1 Tropomyosin like Reo_sigmaC PF04582.7 EME81713.1 - 0.072 12.2 64.7 0.045 12.9 8.0 5.4 1 1 4 5 5 5 0 Reovirus sigma C capsid protein Cast PF10174.4 EME81713.1 - 0.075 11.0 121.0 0.3 9.0 23.2 3.7 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone AAA_27 PF13514.1 EME81713.1 - 1.5 6.4 126.5 23 2.4 24.6 3.1 1 1 1 2 2 2 0 AAA domain Cortex-I_coil PF09304.5 EME81713.1 - 8.4 6.4 126.3 0.26 11.3 9.6 7.4 2 1 7 9 9 9 0 Cortexillin I, coiled coil F-box-like PF12937.2 EME81716.1 - 2e-10 40.2 4.2 1.2e-09 37.7 2.0 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EME81716.1 - 9.9e-05 21.8 2.4 0.011 15.3 0.3 3.7 2 1 0 2 2 2 1 F-box domain p450 PF00067.17 EME81719.1 - 1.8e-11 43.2 0.4 1.9e-09 36.5 0.3 2.5 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EME81721.1 - 5e-15 55.4 0.0 8.9e-11 41.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME81721.1 - 1.5e-10 40.5 2.3 0.00032 19.7 1.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME81721.1 - 9.6e-06 25.5 1.0 2.8e-05 24.0 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME81721.1 - 1.1e-05 24.5 0.6 5.9e-05 22.1 0.5 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EME81721.1 - 4.7e-05 22.0 2.1 0.0073 14.8 0.8 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EME81721.1 - 0.00031 19.6 4.6 0.0018 17.2 3.0 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EME81721.1 - 0.00037 19.4 0.0 0.00062 18.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EME81721.1 - 0.00095 19.0 0.5 0.0027 17.6 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME81721.1 - 0.0012 19.0 0.1 0.0022 18.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME81721.1 - 0.0031 17.8 2.5 0.028 14.8 1.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME81721.1 - 0.012 14.6 0.5 3.9 6.4 0.2 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EME81721.1 - 0.015 14.9 0.9 0.029 14.0 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EME81721.1 - 0.018 13.8 0.0 0.092 11.5 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.9 EME81721.1 - 0.033 12.8 3.4 0.2 10.2 0.7 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EME81721.1 - 0.034 13.2 0.5 0.061 12.4 0.3 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EME81721.1 - 0.036 13.1 0.3 0.048 12.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME81721.1 - 0.071 12.8 6.3 2.4 7.8 0.6 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EME81721.1 - 0.2 11.1 0.4 0.38 10.3 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EME81722.1 - 2.4e-81 273.5 0.0 3.9e-81 272.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EME81722.1 - 4.6e-36 123.9 0.0 1.1e-35 122.7 0.0 1.7 2 0 0 2 2 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EME81722.1 - 1.1e-06 28.7 0.0 5.2e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME81722.1 - 1.5e-06 27.3 0.0 3e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME81722.1 - 8.6e-06 26.0 0.0 0.0004 20.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME81722.1 - 5.6e-05 21.7 0.0 0.00016 20.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EME81722.1 - 5.8e-05 23.0 0.1 0.00041 20.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME81722.1 - 0.00046 19.2 0.1 0.00077 18.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME81722.1 - 0.0007 18.5 1.0 0.0012 17.7 0.0 1.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 EME81722.1 - 0.00072 19.6 0.0 0.0029 17.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME81722.1 - 0.0013 17.8 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EME81722.1 - 0.0057 15.5 0.0 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EME81722.1 - 0.0086 15.2 2.1 0.036 13.1 0.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EME81722.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain 3HCDH_N PF02737.13 EME81722.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EME81722.1 - 0.08 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 EME81722.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 EME81722.1 - 0.23 11.0 0.6 0.76 9.3 0.0 2.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_deac_1 PF01522.16 EME81723.1 - 9.6e-21 73.6 0.0 1.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EME81723.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Acyl_CoA_thio PF02551.10 EME81723.1 - 0.15 11.6 0.3 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA thioesterase Oxidored_FMN PF00724.15 EME81724.1 - 7.6e-90 301.3 0.0 7.9e-89 297.9 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 EME81725.1 - 6.1e-38 130.1 4.6 9.9e-38 129.4 3.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EME81725.1 - 4.2e-08 33.0 13.9 0.0002 21.4 0.6 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME81725.1 - 9e-07 28.7 12.3 0.001 19.2 0.7 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger Transp_cyt_pur PF02133.10 EME81726.1 - 3.3e-13 48.9 37.7 6.8e-13 47.9 26.1 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EME81727.1 - 1.4e-24 86.8 0.0 2.5e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME81727.1 - 1.1e-18 67.3 0.0 2.1e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ECH PF00378.15 EME81728.1 - 4e-25 88.3 0.0 6.1e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Motilin_assoc PF04643.7 EME81729.1 - 0.027 13.9 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide HsbA PF12296.3 EME81730.1 - 2.5e-13 49.9 0.5 3.3e-13 49.5 0.3 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A NPP1 PF05630.6 EME81733.1 - 2.8e-53 180.7 1.3 3.4e-53 180.4 0.9 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DnaJ PF00226.26 EME81735.1 - 5.3e-25 86.9 1.8 9.3e-25 86.1 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME81735.1 - 2.2e-21 75.5 0.8 1.2e-19 69.9 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain NAD_binding_2 PF03446.10 EME81736.1 - 8.6e-35 119.9 0.1 1.1e-34 119.6 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME81736.1 - 6.6e-28 97.2 0.0 1.1e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EME81736.1 - 7.3e-08 31.7 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME81736.1 - 5.1e-06 26.8 0.1 1.4e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EME81736.1 - 0.00038 20.1 0.2 0.0021 17.7 0.0 2.2 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EME81736.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.7 EME81736.1 - 0.0024 17.2 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EME81736.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EME81736.1 - 0.061 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RP-C_C PF11800.3 EME81738.1 - 0.011 15.4 0.2 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region HALZ PF02183.13 EME81738.1 - 0.026 14.2 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper CD99L2 PF12301.3 EME81738.1 - 0.042 13.5 1.7 0.055 13.1 1.2 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 FAM60A PF15396.1 EME81738.1 - 0.065 12.9 1.8 0.084 12.6 1.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Nucleo_P87 PF07267.6 EME81739.1 - 3.2 6.3 5.2 3.9 6.0 3.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Epimerase PF01370.16 EME81740.1 - 0.00094 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME81740.1 - 0.0011 17.9 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 EME81740.1 - 0.012 15.8 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EME81740.1 - 0.021 14.7 0.2 0.14 12.0 0.0 2.0 1 1 0 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EME81740.1 - 0.089 12.7 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME81740.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EME81740.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 EME81741.1 - 9.5e-23 80.4 0.0 1.4e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME81741.1 - 4.5e-16 59.1 0.1 9.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME81741.1 - 5.2e-16 59.2 1.0 7.5e-16 58.7 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME81741.1 - 1.5e-15 57.4 0.9 1.1e-14 54.7 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME81741.1 - 1.6e-14 53.9 0.0 3.5e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME81741.1 - 4.9e-14 52.0 0.0 1.3e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EME81741.1 - 3.3e-13 49.6 0.1 1.3e-12 47.6 0.1 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EME81741.1 - 7.2e-12 45.5 0.8 1.8e-11 44.2 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME81741.1 - 1.6e-09 37.7 0.2 4.1e-09 36.4 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME81741.1 - 1.4e-07 31.0 0.2 3.6e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EME81741.1 - 1.6e-06 27.8 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 EME81741.1 - 6.2e-06 25.4 0.0 8.9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EME81741.1 - 2.7e-05 24.2 0.0 7.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EME81741.1 - 0.0028 16.8 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 EME81741.1 - 0.004 17.9 0.1 0.0098 16.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EME81741.1 - 0.012 14.7 0.1 0.062 12.3 0.1 1.8 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_4 PF02390.12 EME81741.1 - 0.013 14.5 0.0 0.029 13.4 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_5 PF01795.14 EME81741.1 - 0.022 14.0 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family tRNA_U5-meth_tr PF05958.6 EME81741.1 - 0.034 12.8 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TPMT PF05724.6 EME81741.1 - 0.04 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltrans_SAM PF10672.4 EME81741.1 - 0.059 12.2 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_3 PF01596.12 EME81741.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase FmrO PF07091.6 EME81741.1 - 0.08 11.9 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MFS_1 PF07690.11 EME81742.1 - 6.9e-36 123.6 35.0 6.9e-36 123.6 24.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1003 PF06210.6 EME81742.1 - 0.52 10.2 2.7 12 5.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Amidase PF01425.16 EME81745.1 - 3.3e-99 332.7 0.0 3.9e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 Amidase UreF PF01730.11 EME81747.1 - 4.7e-14 52.7 0.1 6.5e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 UreF DUF544 PF04424.8 EME81748.1 - 1.8e-10 40.6 0.0 3.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) GARS_A PF01071.14 EME81749.1 - 1.2e-80 269.7 0.0 1.7e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EME81749.1 - 2.1e-34 117.9 0.1 4.4e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EME81749.1 - 1.1e-29 102.4 0.6 2.2e-29 101.4 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EME81749.1 - 1.5e-13 50.9 0.0 9e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME81749.1 - 1.4e-08 33.9 0.0 4.8e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EME81749.1 - 2e-07 30.4 0.0 3.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EME81749.1 - 2.5e-06 26.9 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EME81749.1 - 4.6e-05 23.3 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EME81749.1 - 0.0094 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME81749.1 - 0.025 13.9 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.5 EME81749.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain PBP_dimer PF03717.10 EME81750.1 - 0.031 14.3 0.1 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain Peroxin-3 PF04882.7 EME81753.1 - 2.4e-138 461.4 0.0 2.8e-138 461.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Microtub_bind PF13931.1 EME81753.1 - 0.024 14.7 0.9 0.061 13.4 0.6 1.7 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding Tho2 PF11262.3 EME81754.1 - 1.3e-74 250.9 0.5 2e-74 250.3 0.4 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EME81754.1 - 5.9e-24 83.6 0.4 4.3e-23 80.8 0.0 2.8 5 0 0 5 5 5 1 Transcription- and export-related complex subunit BROMI PF14961.1 EME81754.1 - 1.7 5.7 0.1 2.4 5.1 0.1 1.1 1 0 0 1 1 1 0 Broad-minded protein DUF106 PF01956.11 EME81754.1 - 3.9 6.9 4.6 1 8.9 0.2 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 Gtr1_RagA PF04670.7 EME81757.1 - 5.9e-86 287.3 0.4 7.1e-86 287.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EME81757.1 - 4.1e-10 39.2 0.1 6.5e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EME81757.1 - 1.2e-09 37.6 0.1 5.3e-09 35.5 0.0 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EME81757.1 - 3.8e-07 30.6 0.1 1.2e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EME81757.1 - 1.5e-06 28.1 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.8 EME81757.1 - 0.0027 16.6 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SRPRB PF09439.5 EME81757.1 - 0.004 16.3 0.0 0.0069 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EME81757.1 - 0.0042 16.5 0.4 0.06 12.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EME81757.1 - 0.0046 17.2 0.1 0.0097 16.2 0.0 1.8 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EME81757.1 - 0.0099 16.0 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME81757.1 - 0.017 14.2 0.2 0.044 12.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EME81757.1 - 0.034 13.3 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EME81757.1 - 0.52 8.9 4.4 6.9 5.2 0.2 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Fungal_trans PF04082.13 EME81759.1 - 1.4e-13 50.3 0.2 1.9e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81759.1 - 0.00011 22.0 10.4 0.00025 20.9 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.9 EME81762.1 - 2.5e-151 503.5 11.2 3.4e-151 503.1 7.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 FAD_binding_3 PF01494.14 EME81764.1 - 1.4e-21 77.0 0.0 3.3e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME81764.1 - 0.0082 16.5 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME81764.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CCHC_2 PF13696.1 EME81766.1 - 0.00011 21.6 0.2 0.00028 20.3 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EME81766.1 - 0.00048 19.9 3.2 0.00076 19.2 2.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EME81766.1 - 0.064 12.9 1.6 0.17 11.5 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle FAM176 PF14851.1 EME81766.1 - 0.47 10.1 3.8 1.1 8.9 2.6 1.7 1 0 0 1 1 1 0 FAM176 family TFIIF_alpha PF05793.7 EME81766.1 - 0.64 8.3 13.0 1.1 7.5 9.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.8 EME81766.1 - 1 7.0 5.3 1.5 6.5 3.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi MPP6 PF10175.4 EME81766.1 - 1.7 9.0 6.6 5.2 7.4 0.2 2.8 3 0 0 3 3 3 0 M-phase phosphoprotein 6 Fungal_trans PF04082.13 EME81767.1 - 1.2e-11 43.9 0.0 2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81767.1 - 1.7e-06 27.8 11.1 3.3e-06 26.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IDO PF01231.13 EME81768.1 - 7.1e-140 466.1 0.0 8.7e-140 465.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.14 EME81769.1 - 1.8e-06 26.9 0.0 3.2e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V ADC PF06314.6 EME81770.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.4 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) S1-P1_nuclease PF02265.11 EME81772.1 - 2.5e-65 220.6 0.2 3.1e-65 220.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Blt1 PF12754.2 EME81773.1 - 2.2e-26 93.2 9.7 6.2e-25 88.4 6.8 2.5 1 1 0 1 1 1 1 Cell-cycle control medial ring component ubiquitin PF00240.18 EME81773.1 - 2.2e-07 30.1 0.2 3.8e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME81773.1 - 1.7e-05 24.4 0.3 2.9e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3695 PF12494.3 EME81773.1 - 0.016 14.9 0.1 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) Pro_isomerase PF00160.16 EME81774.1 - 9.1e-41 139.6 0.0 9.1e-41 139.6 0.0 1.9 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1943 PF09172.6 EME81774.1 - 2.7 6.7 6.4 25 3.6 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Pox_E10 PF04805.7 EME81775.1 - 0.099 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 E10-like protein conserved region mono-CXXC PF15626.1 EME81775.1 - 2 8.4 5.3 0.45 10.4 0.1 2.5 2 0 0 2 2 2 0 single CXXC unit Cofilin_ADF PF00241.15 EME81776.1 - 1.4e-32 112.2 0.1 1.8e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Fumerase PF05681.9 EME81776.1 - 0.032 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NmrA PF05368.8 EME81777.1 - 6.9e-15 54.9 0.6 1.2e-12 47.5 0.0 2.7 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EME81777.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Na_H_Exchanger PF00999.16 EME81778.1 - 9.7e-68 228.4 37.2 1.2e-67 228.1 25.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM_2 PF13703.1 EME81778.1 - 0.061 13.5 0.2 0.061 13.5 0.2 4.0 4 1 0 4 4 4 0 PepSY-associated TM helix MFS_2 PF13347.1 EME81779.1 - 4e-09 35.3 11.3 4e-09 35.3 7.9 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein ATG16 PF08614.6 EME81780.1 - 0.14 11.9 13.6 0.22 11.3 8.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EME81780.1 - 0.27 10.2 7.6 0.42 9.5 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AbiH PF14253.1 EME81780.1 - 0.27 10.7 2.1 0.22 11.1 0.3 1.7 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH V_ATPase_I PF01496.14 EME81780.1 - 0.48 8.2 3.1 0.86 7.3 2.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EME81780.1 - 5.4 6.6 11.4 13 5.4 5.8 2.2 1 1 1 2 2 2 0 Mnd1 family AIRS_C PF02769.17 EME81781.1 - 5e-29 101.2 0.3 8.5e-29 100.5 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EME81781.1 - 1.5e-16 60.4 0.6 3.8e-16 59.0 0.4 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GHMP_kinases_N PF00288.21 EME81781.1 - 3.1e-14 52.7 0.2 1.6e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME81781.1 - 0.0001 22.3 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal MOSC_N PF03476.11 EME81782.1 - 2e-16 59.7 0.0 3.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EME81782.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Fungal_trans_2 PF11951.3 EME81783.1 - 3.2e-14 52.3 4.6 4.9e-07 28.6 0.1 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81783.1 - 5.1e-10 39.0 14.7 8.8e-10 38.3 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.17 EME81784.1 - 9.4e-11 41.3 0.0 1.7e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EME81784.1 - 0.002 17.5 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Abhydrolase_6 PF12697.2 EME81785.1 - 3.1e-15 56.6 0.6 4.6e-15 56.1 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME81785.1 - 2.3e-09 37.1 0.0 4e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 EME81787.1 - 6.2e-16 57.9 8.0 1e-15 57.2 5.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81787.1 - 6.5e-06 25.9 6.0 1.2e-05 25.0 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EME81788.1 - 7.7e-45 152.5 0.0 9.6e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EME81788.1 - 1.7e-21 76.9 17.8 1.6e-10 40.8 7.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 EME81788.1 - 1.3e-10 40.6 0.2 1.5e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EME81788.1 - 3.6e-09 36.8 10.3 0.00023 21.1 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain T2SE PF00437.15 EME81788.1 - 1.2e-07 30.8 0.1 0.013 14.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.14 EME81788.1 - 2.9e-07 30.1 0.2 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EME81788.1 - 4.8e-07 29.8 0.7 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EME81788.1 - 6.9e-07 29.4 0.2 0.065 13.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME81788.1 - 2.3e-06 27.1 0.1 0.018 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EME81788.1 - 3.5e-06 26.6 1.5 0.0065 15.9 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 EME81788.1 - 4e-06 26.4 0.1 0.061 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_21 PF13304.1 EME81788.1 - 4.3e-06 26.8 0.6 0.67 9.8 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.1 EME81788.1 - 1.3e-05 25.5 0.6 0.042 14.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME81788.1 - 3.1e-05 24.7 0.0 0.23 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EME81788.1 - 5.9e-05 22.8 0.1 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EME81788.1 - 9.5e-05 22.7 0.0 0.43 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EME81788.1 - 0.00013 21.2 0.8 9.9 5.3 0.0 4.1 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.4 EME81788.1 - 0.00025 19.7 0.2 0.25 9.9 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 EME81788.1 - 0.00026 20.7 1.3 0.26 10.9 0.1 2.5 2 0 0 2 2 2 2 NTPase AAA_19 PF13245.1 EME81788.1 - 0.00029 20.5 0.4 0.2 11.4 0.0 3.3 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EME81788.1 - 0.00031 20.4 0.7 0.73 9.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Mg_chelatase PF01078.16 EME81788.1 - 0.00042 19.5 0.2 0.68 9.0 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EME81788.1 - 0.00047 19.3 0.0 0.6 9.1 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin Miro PF08477.8 EME81788.1 - 0.00052 20.5 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EME81788.1 - 0.0012 18.7 0.0 0.64 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EME81788.1 - 0.0016 18.4 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Pox_A32 PF04665.7 EME81788.1 - 0.0016 17.7 0.1 0.54 9.4 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_14 PF13173.1 EME81788.1 - 0.0018 18.1 0.0 0.53 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME81788.1 - 0.0047 16.1 0.0 0.9 8.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DEAD PF00270.24 EME81788.1 - 0.0096 15.4 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SbcCD_C PF13558.1 EME81788.1 - 0.01 15.7 1.6 1.5 8.7 0.1 3.7 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EME81788.1 - 0.024 13.4 0.1 3.1 6.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EME81788.1 - 0.04 13.7 0.0 7.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 EME81788.1 - 0.053 13.0 1.1 7.8 5.9 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 EME81788.1 - 0.054 12.9 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EME81788.1 - 0.055 13.1 0.0 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 EME81788.1 - 0.057 13.1 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EME81788.1 - 0.084 12.4 0.4 14 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME81788.1 - 0.11 12.4 0.3 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EME81788.1 - 0.13 11.3 0.4 8.6 5.4 0.0 2.3 2 0 0 2 2 2 0 KaiC DAP3 PF10236.4 EME81788.1 - 0.16 10.9 0.1 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 EME81788.1 - 0.22 11.1 0.3 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 GTP_EFTU PF00009.22 EME81788.1 - 0.26 10.6 0.2 29 4.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 EME81788.1 - 0.44 9.3 0.4 22 3.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Methyltransf_18 PF12847.2 EME81789.1 - 9.5e-10 39.0 0.0 2.6e-09 37.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME81789.1 - 4.3e-07 29.6 0.0 1.4e-06 27.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME81789.1 - 8.9e-05 22.7 0.0 0.00052 20.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME81789.1 - 0.00041 20.1 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME81789.1 - 0.013 15.9 0.0 0.052 14.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EME81789.1 - 0.017 15.6 0.0 0.052 14.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME81789.1 - 0.029 13.7 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DUF3328 PF11807.3 EME81790.1 - 3e-46 157.8 0.8 3.5e-46 157.6 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1673 PF07895.6 EME81790.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3328 PF11807.3 EME81791.1 - 2.1e-23 83.1 0.0 2.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.15 EME81792.1 - 6.4e-33 114.7 12.2 8.4e-33 114.3 8.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3328 PF11807.3 EME81793.1 - 8.4e-27 94.2 6.9 9.5e-27 94.0 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S41 PF03572.13 EME81794.1 - 4.1e-11 42.5 0.0 8.1e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family S41 Acetyltransf_9 PF13527.1 EME81794.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3328 PF11807.3 EME81795.1 - 4e-38 131.2 2.8 4.8e-38 131.0 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Herpes_US9 PF06072.6 EME81795.1 - 0.041 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Pkinase PF00069.20 EME81799.1 - 0.00044 19.4 0.0 0.00049 19.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EME81800.1 - 4.7e-16 58.9 0.0 8.3e-08 32.4 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EME81800.1 - 1.7e-14 52.7 0.0 0.26 11.1 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EME81800.1 - 1.6e-12 46.3 0.2 1 9.8 0.0 6.7 7 1 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EME81800.1 - 2.3e-11 43.8 0.4 0.03 14.8 0.0 5.3 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME81800.1 - 0.0001 22.4 0.1 22 5.4 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME81802.1 - 2.3e-33 114.3 1.3 3.1e-07 30.6 0.2 6.9 4 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EME81802.1 - 1.6e-25 87.6 15.0 0.00013 21.5 0.0 9.3 9 1 0 9 9 9 4 Ankyrin repeat Pkinase PF00069.20 EME81802.1 - 1.1e-22 80.4 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 EME81802.1 - 1.2e-21 76.2 10.5 9.6e-05 22.5 0.1 8.0 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME81802.1 - 5.2e-18 65.0 6.6 1.5e-05 25.3 0.1 8.8 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EME81802.1 - 2.8e-17 62.6 0.0 4.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 EME81802.1 - 1.7e-13 49.3 10.1 0.0013 18.7 0.0 9.2 11 0 0 11 11 11 3 Ankyrin repeat Kdo PF06293.9 EME81802.1 - 0.0048 16.0 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EME81802.1 - 0.24 10.1 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EME81803.1 - 1.8e-07 30.6 0.0 3.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81803.1 - 1.3e-05 24.4 0.0 9.3e-05 21.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EME81803.1 - 0.021 13.6 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Nop14 PF04147.7 EME81805.1 - 9 4.0 11.0 11 3.7 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family LTV PF04180.9 EME81807.1 - 3.8e-77 260.5 13.7 8.5e-76 256.1 9.5 2.8 1 1 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EME81808.1 - 1.4e-17 63.6 0.1 3.6e-15 55.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EME81808.1 - 3.2e-06 26.5 0.1 9.5e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EME81808.1 - 0.00051 19.2 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SDA1 PF05285.7 EME81808.1 - 0.0092 15.2 16.6 0.019 14.2 11.5 1.4 1 0 0 1 1 1 1 SDA1 AIG1 PF04548.11 EME81808.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.18 EME81808.1 - 0.065 13.0 0.0 0.065 13.0 0.0 2.5 3 0 0 3 3 3 0 Dynamin family Miro PF08477.8 EME81808.1 - 0.074 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF1295 PF06966.7 EME81810.1 - 1.4e-15 57.2 1.2 2.2e-15 56.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EME81810.1 - 0.0096 15.6 1.3 0.016 14.9 0.9 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase FlxA PF14282.1 EME81810.1 - 0.037 13.9 0.3 0.037 13.9 0.2 2.7 3 0 0 3 3 3 0 FlxA-like protein DUF3138 PF11336.3 EME81810.1 - 0.12 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) F-box PF00646.28 EME81811.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain FA_hydroxylase PF04116.8 EME81812.1 - 2.2e-15 57.0 22.2 3.7e-14 53.1 12.4 2.5 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Adap_comp_sub PF00928.16 EME81815.1 - 5.1e-91 304.4 0.0 6.5e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME81815.1 - 5.4e-10 39.1 0.3 8.8e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L27 PF01016.14 EME81816.1 - 6.6e-26 89.9 0.4 1.2e-25 89.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.1 EME81816.1 - 0.00052 19.2 0.1 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region Macoilin PF09726.4 EME81817.1 - 7.9 4.6 11.9 11 4.1 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein IPP-2 PF04979.9 EME81820.1 - 5.5e-10 39.6 18.4 1.8e-07 31.4 0.8 2.5 2 1 1 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.3 EME81820.1 - 0.012 15.2 0.5 0.2 11.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Brix PF04427.13 EME81822.1 - 7.2e-38 130.1 0.0 9.8e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Daxx PF03344.10 EME81822.1 - 0.086 11.3 16.6 0.1 11.0 11.5 1.1 1 0 0 1 1 1 0 Daxx Family tRNA-synt_2b PF00587.20 EME81823.1 - 1e-56 191.2 0.1 2.3e-56 190.0 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EME81823.1 - 9.9e-19 67.0 1.4 3.2e-18 65.4 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain Herpes_BBRF1 PF04793.7 EME81824.1 - 0.019 13.7 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 BRRF1-like protein R3H PF01424.17 EME81825.1 - 6.2e-12 45.0 0.1 1.6e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EME81825.1 - 2.7e-08 33.6 0.1 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME81825.1 - 2.5e-07 30.2 0.0 4.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME81825.1 - 0.0073 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M66 PF10462.4 EME81825.1 - 0.14 10.9 0.4 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Peptidase M66 RRM_2 PF04059.7 EME81825.1 - 0.15 12.1 0.1 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 GYF PF02213.11 EME81827.1 - 7.6e-10 38.2 0.3 1.6e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.1 EME81827.1 - 0.026 14.6 0.4 0.071 13.2 0.3 1.8 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Ribosomal_L37e PF01907.14 EME81828.1 - 0.042 13.6 0.8 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-CHY PF05495.7 EME81828.1 - 0.044 13.9 4.2 0.051 13.7 0.0 2.3 1 1 0 2 2 2 0 CHY zinc finger Glyco_hydro_43 PF04616.9 EME81830.1 - 9.2e-31 106.9 0.0 1.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TPP_enzyme_N PF02776.13 EME81831.1 - 3.7e-24 85.1 0.8 3e-22 78.9 0.4 2.5 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME81831.1 - 1.5e-15 57.0 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME81831.1 - 2.4e-14 53.2 0.0 8.1e-14 51.5 0.0 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.11 EME81832.1 - 1e-27 96.7 31.5 1e-27 96.7 21.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UCR_UQCRX_QCR9 PF05365.7 EME81832.1 - 0.018 14.6 1.0 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like PIG-X PF08320.7 EME81833.1 - 1.4e-66 223.7 0.0 1.9e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Abhydrolase_6 PF12697.2 EME81835.1 - 3.5e-25 89.2 0.0 4.5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME81835.1 - 5.5e-15 55.5 0.0 1.9e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME81835.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME81835.1 - 7e-07 29.0 0.1 1.6e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EME81835.1 - 0.00025 20.4 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EME81835.1 - 0.0024 16.9 0.0 0.0033 16.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Chlorophyllase PF07224.6 EME81835.1 - 0.0076 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.15 EME81835.1 - 0.026 14.7 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 EME81835.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.2 EME81835.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.6 EME81835.1 - 0.15 11.1 0.0 3.7 6.5 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ham1p_like PF01725.11 EME81836.1 - 1.3e-48 164.8 0.0 3.6e-48 163.4 0.0 1.6 1 1 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EME81837.1 - 8.7e-27 93.9 0.2 8.7e-27 93.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME81837.1 - 1.9e-15 57.7 3.5 1.1e-14 55.2 2.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME81837.1 - 3.6e-06 26.8 0.0 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME81837.1 - 1.3e-05 25.2 0.1 4.7e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 EME81837.1 - 5.3e-05 23.1 0.6 0.00077 19.3 0.0 2.2 1 1 1 2 2 2 1 Adenylate kinase AAA PF00004.24 EME81837.1 - 6.5e-05 23.1 0.2 0.0004 20.6 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EME81837.1 - 0.0012 18.6 0.9 0.0016 18.1 0.1 1.6 2 0 0 2 2 1 1 NTPase Thymidylate_kin PF02223.12 EME81837.1 - 0.0023 17.3 0.3 1 8.6 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.1 EME81837.1 - 0.0024 18.0 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME81837.1 - 0.0043 17.0 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 EME81837.1 - 0.0045 16.2 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 MobB PF03205.9 EME81837.1 - 0.0073 16.0 0.4 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EME81837.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EME81837.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EME81837.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Cytidylate_kin2 PF13189.1 EME81837.1 - 0.016 15.0 0.3 0.065 13.1 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.17 EME81837.1 - 0.023 14.5 0.3 0.16 11.8 0.2 2.0 1 1 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 EME81837.1 - 0.041 14.0 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EME81837.1 - 0.044 13.5 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EME81837.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EME81837.1 - 0.068 12.7 0.2 0.13 11.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.12 EME81837.1 - 0.079 12.4 0.2 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 EME81837.1 - 0.089 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Miro PF08477.8 EME81837.1 - 0.093 13.2 0.3 0.31 11.5 0.0 1.9 1 1 0 2 2 2 0 Miro-like protein SRP54 PF00448.17 EME81837.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 EME81837.1 - 0.11 11.2 2.2 0.25 10.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 EME81837.1 - 0.16 11.7 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EME81837.1 - 0.22 10.9 0.6 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pyr_excise PF03013.9 EME81837.1 - 0.39 10.4 2.9 1 9.1 0.7 2.1 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase CR6_interact PF10147.4 EME81837.1 - 0.75 9.0 4.9 1 8.6 3.4 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ribosomal_S3Ae PF01015.13 EME81838.1 - 7.2e-81 270.1 4.8 8.4e-81 269.9 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DER1 PF04511.10 EME81839.1 - 7.3e-32 110.4 3.6 8.5e-32 110.2 2.5 1.0 1 0 0 1 1 1 1 Der1-like family DUF2589 PF11655.3 EME81839.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) Sugar_tr PF00083.19 EME81840.1 - 2.2e-87 293.5 25.7 2.7e-87 293.2 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME81840.1 - 4.9e-14 51.8 45.3 1.1e-11 44.1 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EME81842.1 - 2.8e-14 52.5 0.0 1.5e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 AMPKBI PF04739.10 EME81844.1 - 3.7e-29 100.5 7.1 7.4e-29 99.5 0.5 2.5 2 0 0 2 2 2 2 5'-AMP-activated protein kinase beta subunit, interation domain DNA_binding_1 PF01035.15 EME81845.1 - 8.4e-23 79.9 0.0 1.1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3533 PF12051.3 EME81846.1 - 0.085 11.5 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) F-box-like PF12937.2 EME81848.1 - 0.0032 17.1 0.1 0.0074 15.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF1838 PF08894.6 EME81848.1 - 0.039 13.1 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) F-box-like_2 PF13013.1 EME81849.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 EME81849.1 - 0.15 11.8 0.6 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.20 EME81850.1 - 7.6e-28 97.3 0.0 3e-27 95.4 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81850.1 - 1.9e-09 37.0 0.0 1.8e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME81850.1 - 0.087 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EME81851.1 - 5.6e-27 94.5 0.0 1.4e-26 93.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81851.1 - 5.6e-08 32.1 0.0 1.4e-06 27.5 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME81853.1 - 8.6e-24 84.0 0.0 2.4e-23 82.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81853.1 - 0.00031 19.8 0.0 0.033 13.2 0.0 3.2 1 1 0 1 1 1 1 Protein tyrosine kinase adh_short PF00106.20 EME81854.1 - 3e-22 79.2 0.0 4.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81854.1 - 1.9e-09 37.4 0.0 5e-09 36.0 0.0 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EME81854.1 - 1.8e-05 23.7 0.1 3.3e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EME81854.1 - 0.009 15.4 0.1 0.028 13.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EME81854.1 - 0.089 12.1 0.1 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.13 EME81854.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GATase PF00117.23 EME81854.1 - 0.16 11.3 0.2 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I AdoHcyase_NAD PF00670.16 EME81854.1 - 0.85 9.4 4.3 1.6 8.5 2.8 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF572 PF04502.8 EME81855.1 - 3.2e-75 253.3 8.2 3.9e-75 253.0 5.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 EME81855.1 - 0.002 17.9 0.9 0.005 16.6 0.6 1.6 1 1 0 1 1 1 1 Benyvirus 14KDa protein DUF866 PF05907.8 EME81855.1 - 0.0078 15.7 0.8 0.012 15.0 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-ribbon_3 PF13248.1 EME81855.1 - 0.052 12.7 0.7 0.75 9.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF4207 PF13904.1 EME81855.1 - 0.077 12.3 5.3 0.13 11.5 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) TPR_2 PF07719.12 EME81856.1 - 2e-32 108.4 21.6 0.00024 20.8 0.2 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat Apc3 PF12895.2 EME81856.1 - 9.1e-28 96.2 19.7 6.7e-20 71.0 0.9 5.5 4 2 2 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EME81856.1 - 2.7e-27 94.2 24.0 2.7e-06 26.9 0.1 7.4 5 2 1 7 7 7 7 TPR repeat TPR_1 PF00515.23 EME81856.1 - 9.6e-26 88.2 17.6 3.4e-05 23.2 0.5 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EME81856.1 - 7.6e-21 74.2 23.9 5e-06 27.0 0.6 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME81856.1 - 8.3e-21 74.1 19.7 4.6e-06 26.8 0.1 8.3 5 3 3 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EME81856.1 - 2.5e-19 67.5 7.2 0.0021 17.6 0.1 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME81856.1 - 3.2e-17 62.2 25.8 1.3e-06 28.2 0.2 8.2 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME81856.1 - 1e-16 59.8 20.6 0.042 14.4 0.2 10.4 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EME81856.1 - 1.5e-08 33.8 20.1 0.062 13.1 0.1 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 EME81856.1 - 4.5e-07 29.6 17.6 0.022 14.5 0.3 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME81856.1 - 6e-07 29.5 19.5 0.46 11.0 0.1 8.5 8 2 1 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 EME81856.1 - 3.3e-06 26.8 20.2 0.33 10.9 0.2 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat SNAP PF14938.1 EME81856.1 - 0.0013 17.9 15.2 0.48 9.5 0.0 4.8 4 1 0 5 5 5 2 Soluble NSF attachment protein, SNAP PPR PF01535.15 EME81856.1 - 0.0022 17.8 0.5 6.1 7.0 0.0 4.0 4 0 0 4 4 3 1 PPR repeat TPR_4 PF07721.9 EME81856.1 - 0.0032 17.7 16.4 1.9 9.1 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME81856.1 - 0.0041 17.2 15.0 28 5.2 0.0 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat ChAPs PF09295.5 EME81856.1 - 0.005 15.6 0.5 0.15 10.8 0.1 2.5 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 EME81856.1 - 0.01 15.9 10.3 3.4 7.8 0.3 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 EME81856.1 - 0.014 14.4 12.8 0.12 11.3 0.2 5.2 3 2 4 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME81856.1 - 0.47 10.3 12.9 15 5.5 0.0 5.9 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat DUF1996 PF09362.5 EME81858.1 - 1.8e-63 214.3 0.9 2.6e-63 213.8 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF2119 PF09892.4 EME81859.1 - 0.052 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Dioxygenase_C PF00775.16 EME81860.1 - 1.5e-46 157.9 0.0 2e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EME81860.1 - 2.8e-13 49.6 0.0 5.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EME81860.1 - 0.0089 16.0 0.0 0.051 13.6 0.0 2.3 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain ABC2_membrane PF01061.19 EME81861.1 - 8.5e-88 292.9 52.7 2.3e-46 157.6 8.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EME81861.1 - 1.5e-34 119.2 0.0 2.6e-16 60.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EME81861.1 - 3.1e-27 94.2 0.5 9.9e-24 82.9 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EME81861.1 - 1e-11 44.5 35.8 2.8e-07 29.9 11.7 2.7 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EME81861.1 - 2.8e-09 36.9 0.0 8.2e-09 35.4 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EME81861.1 - 3e-06 26.7 0.6 0.0059 16.0 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EME81861.1 - 1e-05 26.3 0.0 0.041 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EME81861.1 - 1.1e-05 25.5 0.0 0.035 14.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 EME81861.1 - 2.1e-05 24.4 0.6 0.0036 17.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EME81861.1 - 9.3e-05 21.8 0.5 0.0064 15.9 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EME81861.1 - 0.00014 22.0 0.0 0.13 12.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EME81861.1 - 0.00051 19.7 0.2 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 EME81861.1 - 0.0006 19.0 0.1 0.0031 16.7 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function, DUF258 cobW PF02492.14 EME81861.1 - 0.00073 19.0 1.9 0.011 15.1 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EME81861.1 - 0.001 18.7 0.7 0.89 9.1 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EME81861.1 - 0.0019 18.5 0.1 0.33 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME81861.1 - 0.0043 17.0 2.9 0.047 13.6 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EME81861.1 - 0.0049 16.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EME81861.1 - 0.0061 16.5 0.9 0.086 12.7 0.2 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EME81861.1 - 0.011 15.4 0.9 3.3 7.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 EME81861.1 - 0.012 14.9 0.0 0.18 10.9 0.0 2.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EME81861.1 - 0.012 15.3 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EME81861.1 - 0.042 13.3 0.3 2.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EME81861.1 - 0.091 12.1 0.1 6.4 6.1 0.0 2.6 3 0 0 3 3 2 0 AAA-like domain AAA PF00004.24 EME81861.1 - 0.1 12.8 0.3 26 5.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EME81861.1 - 0.19 12.2 0.0 8.1 6.9 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EME81861.1 - 0.59 9.1 0.0 3.7 6.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EME81861.1 - 2.8 8.2 5.8 0.67 10.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain Opi1 PF08618.5 EME81862.1 - 1.2e-54 185.8 9.3 3.5e-34 118.4 0.8 3.3 1 1 2 3 3 3 3 Transcription factor Opi1 IGF2_C PF08365.6 EME81863.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide NmrA PF05368.8 EME81864.1 - 2.3e-23 82.6 0.0 5.4e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EME81864.1 - 1.9e-06 28.0 0.0 1.4e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME81864.1 - 0.00073 18.5 0.0 0.0019 17.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EME81864.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EME81864.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME81864.1 - 0.11 12.8 0.2 0.4 11.1 0.0 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 EME81865.1 - 1.5e-63 214.3 0.0 2.1e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME81865.1 - 3.5e-24 85.2 0.0 4.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME81865.1 - 4.2e-07 29.2 0.0 1.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME81865.1 - 0.0034 17.1 0.2 0.02 14.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family PhyH PF05721.8 EME81866.1 - 6.3e-09 36.1 0.5 3.8e-08 33.6 0.3 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PNRC PF15365.1 EME81867.1 - 4.7e-05 23.3 2.7 4.7e-05 23.3 1.9 3.2 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator Xpo1 PF08389.7 EME81868.1 - 0.0021 17.9 1.8 0.073 12.9 0.0 3.9 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EME81868.1 - 0.0029 17.4 0.1 0.012 15.4 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain MCM PF00493.18 EME81869.1 - 1.8e-142 474.0 0.1 3.2e-142 473.2 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME81869.1 - 5.2e-19 68.9 0.3 1.6e-18 67.3 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME81869.1 - 8e-06 25.1 0.0 0.00088 18.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EME81869.1 - 1.9e-05 24.3 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EME81869.1 - 0.00053 19.5 0.0 0.0021 17.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME81869.1 - 0.035 13.5 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EME81869.1 - 0.096 12.8 0.2 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EME81869.1 - 0.25 11.7 3.5 0.39 11.1 0.4 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Vps54 PF07928.7 EME81870.1 - 4.3e-45 153.1 0.0 9.3e-45 152.0 0.0 1.6 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EME81870.1 - 1e-09 37.7 1.5 4.7e-08 32.2 0.3 2.9 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) HR1 PF02185.11 EME81870.1 - 0.0099 15.5 0.1 0.05 13.3 0.0 2.2 1 0 0 1 1 1 1 Hr1 repeat ATG16 PF08614.6 EME81870.1 - 0.021 14.6 5.0 1.9 8.2 0.2 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 EME81870.1 - 0.027 14.5 0.8 0.027 14.5 0.6 2.8 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2451 PF10474.4 EME81870.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.6 EME81870.1 - 0.21 11.4 4.0 0.33 10.8 1.5 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cytochrom_B562 PF07361.6 EME81870.1 - 2 8.8 4.9 6.2 7.2 0.5 2.8 2 0 0 2 2 2 0 Cytochrome b562 AMP-binding PF00501.23 EME81873.1 - 2.2e-51 174.5 0.2 6.9e-49 166.3 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME81873.1 - 1.5e-11 45.0 0.0 3.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EME81873.1 - 0.039 12.4 0.5 0.096 11.1 0.0 1.7 2 0 0 2 2 2 0 GH3 auxin-responsive promoter SMI1_KNR4 PF09346.5 EME81874.1 - 5.7e-33 113.7 0.0 9.5e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) TAP_C PF03943.8 EME81875.1 - 0.0018 17.6 0.1 0.0035 16.7 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain RIX1 PF08167.7 EME81876.1 - 8.8e-39 132.8 3.3 8.8e-39 132.8 2.3 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Adeno_E3 PF06040.6 EME81876.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein TPR_2 PF07719.12 EME81877.1 - 1.8e-09 36.7 13.4 0.15 12.0 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME81877.1 - 6.6e-09 35.9 20.0 1.2 9.5 0.0 7.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME81877.1 - 2.5e-06 27.6 20.3 2.9 8.7 0.0 9.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME81877.1 - 2.7e-06 26.9 16.9 0.0017 17.9 0.0 6.5 7 0 0 7 7 7 2 TPR repeat Apc3 PF12895.2 EME81877.1 - 8.3e-06 25.8 9.7 0.042 13.9 0.1 5.2 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EME81877.1 - 2.4e-05 24.8 17.0 0.31 11.7 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME81877.1 - 3.6e-05 23.2 2.1 1.7 8.5 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME81877.1 - 0.00014 21.2 7.0 2.5 7.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME81877.1 - 0.0064 16.5 9.4 30 5.1 0.0 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EME81877.1 - 0.3 11.0 9.1 21 5.0 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat NOB1_Zn_bind PF08772.6 EME81879.1 - 8.5e-31 105.6 2.6 1.5e-30 104.8 1.8 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EME81879.1 - 0.017 14.6 2.1 0.032 13.7 0.3 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rpr2 PF04032.11 EME81879.1 - 0.055 13.3 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 EME81879.1 - 0.62 10.0 4.0 0.56 10.2 1.3 2.0 2 1 0 2 2 2 0 Zinc ribbon domain Pneumo_att_G PF05539.6 EME81879.1 - 1.2 8.4 7.8 1.8 7.8 5.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G AF1Q PF15017.1 EME81879.1 - 3.3 7.6 7.4 0.38 10.6 1.4 2.3 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Aa_trans PF01490.13 EME81882.1 - 6.2e-12 44.6 30.3 5.5e-08 31.7 8.1 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein GP41 PF00517.12 EME81882.1 - 1.8 8.0 8.6 0.54 9.7 0.5 2.6 2 0 0 2 2 2 0 Retroviral envelope protein Glycos_transf_1 PF00534.15 EME81883.1 - 2e-37 128.2 0.0 2.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME81883.1 - 7.4e-15 55.2 0.3 2.7e-14 53.4 0.0 2.1 3 1 1 4 4 4 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME81883.1 - 4e-10 40.0 0.1 6.8e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EME81883.1 - 4.5e-10 39.6 0.0 1.6e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME81883.1 - 6.4e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Phage_int_SAM_1 PF02899.12 EME81883.1 - 0.34 11.1 2.4 3.2 7.9 0.4 3.0 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Peptidase_C2 PF00648.16 EME81884.1 - 9.7e-33 113.4 4.7 3.5e-11 42.6 0.0 3.3 2 1 1 3 3 3 3 Calpain family cysteine protease adh_short PF00106.20 EME81885.1 - 1.6e-10 41.1 3.7 2.8e-08 33.8 2.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81885.1 - 0.0011 18.6 0.6 0.0023 17.6 0.4 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME81885.1 - 0.0077 15.9 0.5 0.017 14.8 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3425 PF11905.3 EME81886.1 - 8.4e-20 71.0 6.5 2.7e-18 66.1 4.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_3 PF07859.8 EME81887.1 - 7.2e-40 136.8 0.0 9.5e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME81887.1 - 0.0038 15.9 0.2 0.0082 14.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EME81887.1 - 0.0042 15.7 0.0 0.0056 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 EME81887.1 - 0.0057 15.1 0.0 0.035 12.5 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EME81887.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SAC3_GANP PF03399.11 EME81888.1 - 1.9e-45 154.9 0.0 2.7e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Sybindin PF04099.7 EME81890.1 - 3.4e-24 85.1 0.0 4.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EME81890.1 - 0.058 13.2 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Cupin_2 PF07883.6 EME81891.1 - 0.0049 16.3 0.9 0.04 13.4 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EME81891.1 - 0.0095 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.7 EME81891.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.17 EME81891.1 - 0.016 15.4 0.2 0.075 13.2 0.0 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase DUF2205 PF10224.4 EME81893.1 - 0.042 13.4 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Rootletin PF15035.1 EME81893.1 - 0.054 13.4 0.6 0.13 12.1 0.4 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DMPK_coil PF08826.5 EME81893.1 - 0.32 10.9 3.0 0.37 10.7 0.8 2.0 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF4428 PF14471.1 EME81893.1 - 1.4 8.6 5.2 25 4.6 3.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.8 EME81893.1 - 2.2 7.8 5.1 19 4.8 0.4 2.3 1 1 1 2 2 2 0 ClpX C4-type zinc finger PLDc_2 PF13091.1 EME81894.1 - 1.1e-13 50.9 0.0 3.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EME81894.1 - 6.9e-07 28.8 3.5 0.011 15.5 0.4 3.6 3 1 0 3 3 3 2 Phospholipase D Active site motif Herpes_gp2 PF05955.6 EME81896.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 EXS PF03124.9 EME81897.1 - 3.9e-88 295.7 26.0 5e-88 295.4 18.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EME81897.1 - 2.7e-39 135.6 0.1 5.7e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 SPX domain KAT11 PF08214.6 EME81900.1 - 1.1e-75 254.9 0.0 1.4e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Ribonucleas_3_3 PF14622.1 EME81901.1 - 7.8e-26 90.5 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EME81901.1 - 4.1e-09 36.8 0.0 8.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Rad9_Rad53_bind PF08605.5 EME81902.1 - 3.1e-12 46.4 0.0 5.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EME81902.1 - 0.0002 21.4 0.0 0.00088 19.3 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-RanBP PF00641.13 EME81903.1 - 5.5e-19 66.9 11.8 5e-11 41.5 0.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EME81903.1 - 7.2e-11 41.5 0.0 1.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME81903.1 - 4.3e-08 33.0 0.0 1.3e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EME81903.1 - 5.9e-06 26.6 0.0 9.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 EME81903.1 - 1.7 8.5 8.6 1.1 9.1 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon Prenyltrans_2 PF13249.1 EME81904.1 - 3.2e-36 124.1 0.0 1.2e-15 57.9 0.0 6.1 3 2 2 6 6 6 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME81904.1 - 1.6e-28 98.9 0.0 1.4e-13 50.8 0.1 6.3 4 3 2 6 6 6 3 Prenyltransferase-like Prenyltrans PF00432.16 EME81904.1 - 8.8e-23 79.5 16.7 4.9e-09 35.6 0.2 6.5 5 2 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 EME81904.1 - 0.00059 19.1 0.2 8.7 5.4 0.0 4.4 4 1 1 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 EME81904.1 - 0.0019 17.4 0.0 0.095 11.9 0.0 2.9 1 1 1 3 3 3 1 A-macroglobulin complement component Ank_2 PF12796.2 EME81905.1 - 3.9e-18 65.5 0.3 2.5e-14 53.3 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME81905.1 - 5.5e-17 60.6 0.1 1.4e-11 43.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EME81905.1 - 8.3e-17 61.2 4.1 8.8e-09 35.6 0.2 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME81905.1 - 6.4e-14 51.6 2.3 1.1e-09 38.2 0.6 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME81905.1 - 1.9e-13 49.2 0.2 2.3e-09 36.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF3330 PF11809.3 EME81905.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Pept_tRNA_hydro PF01195.14 EME81907.1 - 6.2e-39 133.3 0.0 7e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SAM_decarbox PF01536.11 EME81908.1 - 1.6e-87 293.3 0.0 3.4e-58 196.8 0.0 2.9 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase EHN PF06441.7 EME81909.1 - 2.3e-17 62.9 0.3 4.5e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Glyco_hydro_31 PF01055.21 EME81910.1 - 5.7e-123 411.0 0.1 7.2e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME81910.1 - 1.6e-16 59.8 0.0 2e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF433 PF04255.9 EME81910.1 - 0.12 11.8 0.0 6.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Oxidored_molyb PF00174.14 EME81911.1 - 5.3e-26 91.0 0.0 8.5e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EME81911.1 - 2.7e-23 82.0 0.1 4.7e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain adh_short PF00106.20 EME81912.1 - 1.7e-07 31.3 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81912.1 - 5.2e-05 22.9 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EME81912.1 - 0.023 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PH PF00169.24 EME81913.1 - 0.039 14.1 0.0 0.25 11.5 0.0 2.5 1 1 0 1 1 1 0 PH domain MFS_2 PF13347.1 EME81914.1 - 1.5e-08 33.5 10.1 1.5e-08 33.5 7.0 2.3 3 0 0 3 3 3 1 MFS/sugar transport protein Acyltransferase PF01553.16 EME81915.1 - 2.2e-28 98.3 0.0 3.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EME81916.1 - 1.9e-43 148.2 0.0 2.9e-43 147.6 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Internalin_N PF12354.3 EME81916.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal CFEM PF05730.6 EME81917.1 - 8e-13 48.0 10.4 1.2e-12 47.4 7.2 1.3 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 EME81917.1 - 1.5 9.0 6.9 2.8 8.1 4.8 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain ELO PF01151.13 EME81918.1 - 2.9e-60 203.6 21.0 3.4e-60 203.4 14.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 EME81919.1 - 8.1e-30 101.6 2.4 3.3e-06 26.7 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EME81919.1 - 0.00092 18.7 0.1 0.0073 15.8 0.1 2.3 1 1 0 1 1 1 1 PQQ-like domain CLTH PF10607.4 EME81919.1 - 0.0023 17.6 0.1 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain IKI3 PF04762.7 EME81919.1 - 0.0039 15.1 0.0 0.4 8.4 0.0 2.2 2 0 0 2 2 2 2 IKI3 family PQQ PF01011.16 EME81919.1 - 0.019 14.4 0.0 0.62 9.6 0.0 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat F-box-like PF12937.2 EME81920.1 - 3.5e-07 29.8 0.0 7.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME81920.1 - 5.4e-06 25.9 0.0 1.4e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain adh_short PF00106.20 EME81921.1 - 7.6e-17 61.7 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81921.1 - 3.6e-09 36.5 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME81921.1 - 1.9e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME81921.1 - 8.6e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EME81921.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NUMOD1 PF07453.8 EME81921.1 - 0.021 14.6 0.1 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 NUMOD1 domain Shikimate_DH PF01488.15 EME81921.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tetraspannin PF00335.15 EME81922.1 - 1.4 8.0 15.7 0.098 11.9 5.7 2.2 1 1 0 2 2 2 0 Tetraspanin family GSH_synth_ATP PF03917.12 EME81923.1 - 3.8e-112 374.5 0.0 4.6e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EME81923.1 - 4.6e-35 119.8 0.0 7.6e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EME81924.1 - 3e-45 154.3 0.0 9e-45 152.7 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME81924.1 - 7.5e-17 60.9 0.3 1.8e-16 59.7 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME81924.1 - 3.4e-05 23.7 0.0 0.0032 17.3 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EME81924.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Peptidase_M3 PF01432.15 EME81925.1 - 2.2e-107 359.9 0.3 3.1e-107 359.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 AA_permease PF00324.16 EME81927.1 - 7.6e-133 443.3 48.5 9.5e-133 443.0 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME81927.1 - 5.6e-43 147.0 52.0 6.9e-43 146.7 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3278 PF11683.3 EME81927.1 - 0.97 9.4 11.5 3.6 7.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Prok-RING_1 PF14446.1 EME81928.1 - 0.011 15.5 1.1 0.034 13.8 0.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 CHASE4 PF05228.8 EME81929.1 - 0.087 12.4 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 CHASE4 domain Complex1_LYR_2 PF13233.1 EME81930.1 - 2.9e-05 24.4 0.3 3.7e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME81930.1 - 0.00013 21.6 0.3 0.00028 20.5 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME81930.1 - 0.00028 21.0 0.3 0.00047 20.3 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like R-HINP1I PF11463.3 EME81930.1 - 0.047 13.1 0.1 0.072 12.4 0.1 1.3 1 1 0 1 1 1 0 R.HinP1I restriction endonuclease PINIT PF14324.1 EME81933.1 - 1.1e-29 103.4 0.4 2.2e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 EME81933.1 - 4.4e-19 67.7 2.4 7.8e-19 66.9 1.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EME81933.1 - 1.6e-06 27.5 0.4 3.1e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EME81933.1 - 0.00026 20.4 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain DUF2423 PF10338.4 EME81934.1 - 3.8e-12 45.9 3.5 3.8e-12 45.9 2.4 3.2 3 1 0 4 4 4 1 Protein of unknown function (DUF2423) SopA_C PF13979.1 EME81934.1 - 0.04 13.5 0.7 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 SopA-like catalytic domain zf-MIZ PF02891.15 EME81934.1 - 0.044 13.3 0.5 0.044 13.3 0.4 2.0 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger IZUMO PF15005.1 EME81934.1 - 0.061 13.3 0.4 0.19 11.7 0.3 1.8 1 0 0 1 1 1 0 Izumo sperm-egg fusion Hid1 PF12722.2 EME81934.1 - 1.8 6.1 4.1 2.1 5.9 2.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FNIP_N PF14636.1 EME81935.1 - 0.21 12.0 4.3 0.29 11.5 3.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Pantoate_ligase PF02569.10 EME81935.1 - 1.3 7.7 5.3 4.8 5.8 2.4 1.9 1 1 1 2 2 2 0 Pantoate-beta-alanine ligase DUF4203 PF13886.1 EME81936.1 - 8e-36 123.4 16.8 8.9e-36 123.3 11.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4097 PF13349.1 EME81936.1 - 0.38 10.2 1.1 0.87 9.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Fungal_trans PF04082.13 EME81939.1 - 2.5e-12 46.2 0.0 3.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81939.1 - 7.8e-07 28.9 7.1 1.4e-06 28.0 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2217 PF10265.4 EME81941.1 - 9 4.9 7.2 13 4.3 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) adh_short_C2 PF13561.1 EME81943.1 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME81943.1 - 2.5e-21 76.3 0.5 4e-21 75.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME81943.1 - 3.4e-07 30.1 1.3 2.6e-06 27.2 0.9 2.0 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EME81943.1 - 0.0015 18.9 0.6 0.0029 17.9 0.4 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EME81943.1 - 0.0083 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EME81943.1 - 0.085 12.2 1.0 0.77 9.0 0.7 2.1 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Voldacs PF03517.8 EME81945.1 - 4.8e-12 45.8 1.8 3.7e-11 43.0 1.2 2.1 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling PAN_4 PF14295.1 EME81946.1 - 3.4e-10 39.4 0.6 5.7e-10 38.7 0.4 1.3 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EME81946.1 - 0.0022 17.6 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EME81946.1 - 0.034 13.7 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain MANEC PF07502.9 EME81946.1 - 0.05 13.5 0.9 0.075 13.0 0.6 1.4 1 0 0 1 1 1 0 MANEC domain CarbpepA_inh PF02977.10 EME81946.1 - 0.069 12.7 0.4 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor PAAR_motif PF05488.8 EME81946.1 - 0.089 12.8 0.5 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 PAAR motif PAN_2 PF08276.6 EME81946.1 - 0.26 11.1 2.5 0.33 10.8 1.3 1.5 1 1 0 1 1 1 0 PAN-like domain RNase_T PF00929.19 EME81952.1 - 1.4e-05 25.4 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease API5 PF05918.6 EME81952.1 - 8.1 4.8 5.6 11 4.4 3.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ABC2_membrane PF01061.19 EME81953.1 - 2.6e-30 105.1 30.0 3.8e-30 104.6 20.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME81953.1 - 2.1e-24 86.3 0.1 3.3e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME81953.1 - 6.9e-08 32.8 0.1 0.0012 18.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EME81953.1 - 1.7e-05 24.9 0.1 0.00011 22.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME81953.1 - 2.5e-05 24.3 0.1 4.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME81953.1 - 0.0001 21.5 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EME81953.1 - 0.00014 21.3 0.0 0.00043 19.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME81953.1 - 0.00037 20.4 0.3 0.00062 19.7 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME81953.1 - 0.0004 20.2 0.1 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EME81953.1 - 0.00045 19.7 0.1 0.00074 19.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 EME81953.1 - 0.00079 18.5 27.1 0.00079 18.5 18.8 1.7 1 1 1 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 EME81953.1 - 0.00087 18.5 0.0 0.0043 16.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME81953.1 - 0.0012 18.2 0.3 0.0035 16.8 0.1 1.8 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EME81953.1 - 0.0034 18.1 0.0 0.0079 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EME81953.1 - 0.0046 15.9 0.2 0.0069 15.3 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EME81953.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EME81953.1 - 0.012 15.9 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EME81953.1 - 0.012 15.1 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EME81953.1 - 0.013 15.1 0.2 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.1 EME81953.1 - 0.013 14.5 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EME81953.1 - 0.018 14.4 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EME81953.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EME81953.1 - 0.021 14.3 0.6 0.035 13.6 0.4 1.2 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EME81953.1 - 0.024 13.6 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_19 PF13245.1 EME81953.1 - 0.025 14.3 0.6 0.081 12.6 0.4 1.9 1 1 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 EME81953.1 - 0.031 13.7 0.2 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 EME81953.1 - 0.033 12.6 0.1 0.39 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME81953.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EME81953.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EME81953.1 - 0.055 12.9 0.2 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EME81953.1 - 0.063 12.8 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME81953.1 - 0.07 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EME81953.1 - 0.078 12.1 0.1 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 EME81953.1 - 0.079 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EME81953.1 - 0.093 12.4 0.0 0.29 10.8 0.1 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EME81953.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Thymidylate_kin PF02223.12 EME81953.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_35 PF14516.1 EME81953.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 EME81953.1 - 0.14 12.6 0.1 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein KaiC PF06745.8 EME81953.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EME81953.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EME81953.1 - 0.22 11.8 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-CHCC PF10276.4 EME81954.1 - 3e-16 58.9 1.6 4.5e-16 58.4 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger domain HET PF06985.6 EME81956.1 - 3.6e-27 95.2 0.0 4e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.1 EME81956.1 - 0.071 12.3 0.0 0.084 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) polyprenyl_synt PF00348.12 EME81957.1 - 7.3e-71 238.0 0.1 8.2e-71 237.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase UDPG_MGDP_dh_N PF03721.9 EME81957.1 - 0.0098 15.2 0.2 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain APC8 PF04049.8 EME81958.1 - 3.4e-23 81.9 0.0 6.6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 EME81958.1 - 2.6e-20 71.8 23.4 3e-08 33.2 2.3 6.2 3 1 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 EME81958.1 - 2e-18 65.1 21.2 2.8e-06 26.6 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME81958.1 - 1.5e-17 62.0 28.9 0.00088 19.0 0.0 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EME81958.1 - 8.9e-16 56.9 17.6 0.00069 20.0 0.0 8.0 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EME81958.1 - 1.5e-13 49.4 8.0 2e-05 24.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME81958.1 - 4e-11 42.6 20.7 0.024 14.5 2.5 6.1 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EME81958.1 - 1.1e-10 41.9 21.0 0.0002 21.9 0.1 6.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME81958.1 - 6.9e-09 34.8 17.9 0.087 12.6 0.0 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 EME81958.1 - 4.1e-07 29.7 11.5 0.0039 17.0 0.5 4.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME81958.1 - 4.8e-07 30.0 10.9 0.18 12.1 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EME81958.1 - 2.1e-06 27.7 8.4 0.12 12.4 0.2 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EME81958.1 - 2.4e-05 24.1 15.1 5.8 7.3 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME81958.1 - 7e-05 23.0 10.0 2.1 9.0 0.2 5.8 4 2 0 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 EME81958.1 - 0.024 13.4 0.1 4.9 5.8 0.0 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.1 EME81958.1 - 0.029 13.4 9.8 1.2 8.1 3.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.4 EME81958.1 - 0.2 10.1 0.0 0.2 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) DUF3856 PF12968.2 EME81958.1 - 0.4 10.5 3.5 1.8 8.3 0.2 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) adh_short_C2 PF13561.1 EME81959.1 - 1.9e-09 37.6 0.0 2e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WSC PF01822.14 EME81961.1 - 2.9e-67 222.5 76.5 1.5e-19 69.6 8.8 5.5 4 1 1 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 EME81961.1 - 1.4e-28 99.5 0.0 4.7e-26 91.3 0.0 3.5 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EME81961.1 - 1.1e-22 79.9 0.0 2.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Piwi PF02171.12 EME81962.1 - 1.6e-49 168.5 0.0 1.9e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Piwi domain TPR_4 PF07721.9 EME81963.1 - 0.36 11.4 3.8 1.2 9.7 2.6 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 EME81965.1 - 3e-08 32.6 2.8 4.2e-08 32.1 1.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2809 PF10990.3 EME81965.1 - 0.078 13.3 0.1 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Mg_trans_NIPA PF05653.9 EME81968.1 - 2.8e-61 207.1 5.3 3.7e-57 193.5 3.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EME81968.1 - 2.5e-05 24.4 1.0 2.5e-05 24.4 0.7 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EME81968.1 - 0.0047 16.9 1.1 0.0047 16.9 0.8 3.8 3 1 1 4 4 4 1 EamA-like transporter family SSP160 PF06933.6 EME81968.1 - 0.012 13.6 0.1 0.019 13.0 0.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1593 PF07632.6 EME81970.1 - 3.3e-89 298.6 0.0 4.3e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EME81970.1 - 0.022 13.1 0.0 0.032 12.5 0.0 1.2 1 0 0 1 1 1 0 REJ domain Aldo_ket_red PF00248.16 EME81971.1 - 2.9e-49 167.4 0.0 3.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1649 PF07855.7 EME81973.1 - 1.5e-51 174.3 0.1 1.7e-51 174.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF29 PF01724.11 EME81974.1 - 0.00086 19.1 0.3 0.001 18.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF29 DUF4120 PF13496.1 EME81974.1 - 0.096 12.7 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) DUF4477 PF14780.1 EME81974.1 - 1.8 7.8 4.4 1.7 7.9 1.6 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4477) DUF2933 PF11666.3 EME81974.1 - 3.5 7.2 5.4 6.7 6.3 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) G6PD_C PF02781.11 EME81975.1 - 1.4e-133 444.2 0.0 2.8e-133 443.3 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EME81975.1 - 2.9e-66 223.2 0.1 5e-66 222.4 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CZB PF13682.1 EME81975.1 - 0.046 13.8 0.3 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain Ribosomal_L35Ae PF01247.13 EME81976.1 - 4.6e-43 144.9 1.3 5.3e-43 144.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EME81976.1 - 0.015 15.2 0.0 6.2 6.8 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Brix PF04427.13 EME81977.1 - 3.1e-34 118.3 0.1 4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.18 EME81978.1 - 8.3e-72 241.4 3.0 8.3e-72 241.4 2.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EME81978.1 - 3.6e-47 159.9 20.0 3.6e-47 159.9 13.9 5.5 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EME81978.1 - 5e-16 58.3 0.0 1.4e-15 56.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NAD_binding_4 PF07993.7 EME81979.1 - 3.2e-32 111.4 0.0 5.7e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EME81979.1 - 7e-27 93.8 0.0 1.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.20 EME81979.1 - 1.3e-07 31.6 0.1 4.6e-07 29.9 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EME81979.1 - 2.4e-07 30.4 0.0 4.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME81979.1 - 0.00012 21.8 0.1 0.00032 20.4 0.1 1.8 1 0 0 1 1 1 1 KR domain PP-binding PF00550.20 EME81979.1 - 0.00016 21.8 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EME81979.1 - 0.026 13.4 0.0 0.3 9.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein HET PF06985.6 EME81980.1 - 6.9e-17 61.9 0.0 9.6e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sulfatase PF00884.18 EME81982.1 - 1.5e-77 260.8 0.0 1.9e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EME81982.1 - 0.00024 21.3 0.3 0.013 15.8 0.1 2.8 2 1 0 2 2 2 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EME81982.1 - 0.0064 15.8 0.1 0.26 10.5 0.1 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EME81982.1 - 0.037 12.4 0.0 0.1 10.9 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF229) Pet127 PF08634.5 EME81983.1 - 1.2e-111 372.2 0.9 1.7e-111 371.7 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 BSMAP PF12280.3 EME81984.1 - 0.028 14.2 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein HPP PF04982.8 EME81985.1 - 3.8e-36 123.5 4.4 5.9e-36 122.9 3.1 1.3 1 0 0 1 1 1 1 HPP family DUF4126 PF13548.1 EME81985.1 - 0.082 12.3 7.5 0.16 11.3 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4126) DUF2975 PF11188.3 EME81985.1 - 1.8 8.2 5.5 8.5 6.1 3.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) ARD PF03079.9 EME81986.1 - 2.2e-46 157.6 0.2 2.7e-46 157.3 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EME81986.1 - 4.7e-10 38.8 0.1 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EME81986.1 - 7.8e-06 25.6 0.0 1.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EME81986.1 - 0.00056 19.3 0.0 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Cupin Cupin_8 PF13621.1 EME81986.1 - 0.026 14.0 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Pirin PF02678.11 EME81986.1 - 0.054 13.3 0.1 0.16 11.8 0.0 1.7 1 1 1 2 2 2 0 Pirin Cupin_6 PF12852.2 EME81986.1 - 0.057 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 EME81986.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) NUDIX PF00293.23 EME81987.1 - 2.6e-15 56.2 0.0 5.1e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EME81987.1 - 5.2e-14 52.3 0.0 2.4e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EME81987.1 - 2.8e-06 26.7 1.7 4.9e-06 25.9 1.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain ATG22 PF11700.3 EME81991.1 - 8.7e-166 552.1 18.4 9.8e-166 551.9 12.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EME81991.1 - 2e-05 23.5 47.4 0.00029 19.6 9.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DNA_ligase_A_N PF04675.9 EME81992.1 - 4.6e-21 75.4 0.0 1.9e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 EME81992.1 - 5.2e-20 71.6 0.0 7.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EME81992.1 - 0.0021 18.4 0.0 0.78 10.1 0.0 2.7 2 0 0 2 2 2 2 ATP dependent DNA ligase C terminal region Fungal_trans PF04082.13 EME81993.1 - 1.9e-13 49.9 4.5 3.5e-13 49.0 3.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME81993.1 - 5.6e-09 35.7 8.8 1.1e-08 34.8 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain She9_MDM33 PF05546.6 EME81993.1 - 0.12 11.9 0.3 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 She9 / Mdm33 family DUF4387 PF14330.1 EME81994.1 - 5.2e-19 68.4 0.0 1e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) ATP_bind_2 PF03668.10 EME81995.1 - 0.00019 20.6 0.0 0.0013 17.8 0.0 1.9 2 0 0 2 2 2 1 P-loop ATPase protein family DUF2890 PF11081.3 EME81995.1 - 0.2 11.7 5.8 0.29 11.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nucleoplasmin PF03066.10 EME81995.1 - 1.3 8.5 8.2 2.3 7.7 5.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin 60KD_IMP PF02096.15 EME81996.1 - 1.6e-28 99.7 0.4 3e-28 98.8 0.3 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein YkyA PF10368.4 EME81996.1 - 0.033 13.5 1.4 0.054 12.8 1.0 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Chorion_2 PF03964.10 EME81996.1 - 5.4 7.6 10.1 0.12 12.9 1.3 2.3 2 0 0 2 2 2 0 Chorion family 2 TOM13 PF08219.6 EME81997.1 - 1.3e-30 104.9 0.0 1.8e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EME81998.1 - 1.2e-26 92.8 0.0 2.5e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 EME81998.1 - 2.7e-14 52.4 1.4 5e-14 51.5 1.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EME81998.1 - 9.1e-14 51.2 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EME81998.1 - 0.053 13.3 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 UBA/TS-N domain S-antigen PF05756.6 EME81998.1 - 0.64 10.0 2.6 9.9 6.2 0.2 2.4 2 0 0 2 2 2 0 S-antigen protein Pyr_redox_3 PF13738.1 EME81999.1 - 4.8e-23 82.2 0.0 1.2e-22 81.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME81999.1 - 5e-14 51.3 0.1 8.2e-14 50.6 0.1 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME81999.1 - 1.7e-07 31.3 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME81999.1 - 1.3e-05 25.1 0.0 5.4e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME81999.1 - 6.5e-05 21.9 0.0 0.00027 19.9 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME81999.1 - 0.00027 20.7 0.0 0.00062 19.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 EME81999.1 - 0.00037 19.6 0.2 0.0046 16.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EME81999.1 - 0.0024 16.8 0.0 0.3 9.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME81999.1 - 0.0062 16.9 2.5 0.36 11.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME81999.1 - 0.0077 15.1 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EME81999.1 - 0.025 13.4 0.1 0.047 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.10 EME81999.1 - 0.051 11.7 0.1 2.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.2 EME81999.1 - 0.087 11.8 0.3 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4066 PF13278.1 EME82000.1 - 9.2e-21 73.8 0.0 3.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EME82000.1 - 5.7e-05 22.6 0.0 0.00017 21.1 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family adh_short PF00106.20 EME82001.1 - 3.5e-25 88.8 0.0 4.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME82001.1 - 5.9e-15 55.3 0.0 7.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME82001.1 - 7.9e-11 42.1 0.0 1e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME82001.1 - 2e-09 37.2 0.0 2.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME82001.1 - 5.1e-09 36.4 0.0 1.5e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME82001.1 - 0.00022 20.2 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DUF1776 PF08643.5 EME82001.1 - 0.0019 17.3 0.0 0.0077 15.4 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EME82001.1 - 0.059 13.1 0.3 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Zn_clus PF00172.13 EME82002.1 - 4.2e-11 42.5 11.7 8.6e-11 41.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME82002.1 - 7.2e-10 38.1 0.0 1.8e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1524 PF07510.6 EME82003.1 - 5.5e-13 48.9 0.0 7.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) p450 PF00067.17 EME82006.1 - 3.8e-66 223.5 0.0 5e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLU-1 PF08429.6 EME82008.1 - 3.5e-95 318.7 17.2 1.8e-93 313.0 11.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EME82008.1 - 1.1e-43 148.1 0.4 2.9e-43 146.7 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EME82008.1 - 9.7e-27 92.6 0.1 4.7e-26 90.4 0.0 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EME82008.1 - 3.4e-17 62.2 9.7 1.1e-16 60.6 6.8 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EME82008.1 - 3.5e-16 58.6 35.2 1.4e-09 37.4 6.9 3.0 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EME82008.1 - 5e-16 57.9 1.8 1.4e-15 56.4 1.3 1.9 1 0 0 1 1 1 1 jmjN domain DUF16 PF01519.11 EME82008.1 - 1.4 9.1 5.8 15 5.8 4.0 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 C1_1 PF00130.17 EME82008.1 - 4 7.2 24.2 0.058 13.1 0.8 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EME82008.1 - 9.5 6.1 26.0 2.3 8.1 4.2 2.7 2 0 0 2 2 2 0 Ring finger domain GIY-YIG PF01541.19 EME82009.1 - 5.9e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EME82009.1 - 0.00089 19.1 3.1 0.0018 18.2 2.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 EME82009.1 - 0.0068 16.0 3.9 0.013 15.1 2.7 1.5 1 1 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EME82009.1 - 0.01 15.9 1.9 0.02 15.0 1.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EME82009.1 - 0.017 15.0 1.6 0.035 14.1 1.1 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 EME82009.1 - 0.055 13.3 6.5 0.1 12.4 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain TGT PF01702.13 EME82010.1 - 5.2e-36 124.1 0.0 8.3e-36 123.4 0.0 1.3 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.12 EME82011.1 - 3.9e-46 156.7 0.0 4.5e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EME82011.1 - 8.2e-07 29.1 0.1 1.1e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME82011.1 - 7.8e-05 22.5 0.0 0.00013 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME82011.1 - 0.00017 20.8 0.1 0.00093 18.4 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 SRP54 PF00448.17 EME82011.1 - 0.0013 18.1 0.1 0.076 12.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA PF00004.24 EME82011.1 - 0.0049 17.0 0.1 0.069 13.3 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME82011.1 - 0.0052 17.6 0.0 0.012 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME82011.1 - 0.0062 16.8 0.0 0.065 13.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EME82011.1 - 0.014 15.2 0.1 0.55 10.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain PPK2 PF03976.9 EME82011.1 - 0.014 14.6 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) CENP-F_leu_zip PF10473.4 EME82011.1 - 0.03 14.1 2.8 0.053 13.3 2.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Complex1_LYR_1 PF13232.1 EME82011.1 - 0.16 12.1 0.6 0.48 10.6 0.1 2.0 3 0 0 3 3 3 0 Complex1_LYR-like ATP_bind_1 PF03029.12 EME82011.1 - 0.18 11.3 0.2 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3218 PF11508.3 EME82012.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) Lipoprotein_15 PF03640.10 EME82012.1 - 0.13 11.7 1.8 4.7 6.7 0.1 3.2 3 0 0 3 3 3 0 Secreted repeat of unknown function LRRNT_2 PF08263.7 EME82014.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain MmgE_PrpD PF03972.9 EME82015.1 - 7.1e-65 218.9 0.0 8.3e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RAI1 PF08652.6 EME82016.1 - 4.9e-22 77.4 0.0 9.4e-22 76.5 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Glyco_hydro_43 PF04616.9 EME82017.1 - 9.2e-65 218.5 6.0 1.2e-64 218.1 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Acyl-CoA_dh_1 PF00441.19 EME82019.1 - 3.8e-29 101.7 0.9 7.2e-29 100.8 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME82019.1 - 6.3e-16 57.6 0.1 1.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME82019.1 - 1.1e-14 54.9 0.0 2.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME82019.1 - 3.1e-11 43.6 1.5 5.6e-11 42.8 0.7 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Gly_transf_sug PF04488.10 EME82020.1 - 8.4e-19 67.8 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EME82020.1 - 0.17 10.3 4.5 0.11 11.0 0.4 1.9 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain p450 PF00067.17 EME82021.1 - 7.2e-68 229.1 0.0 8.8e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1257 PF06868.6 EME82021.1 - 0.025 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) SEN1_N PF12726.2 EME82021.1 - 0.04 11.9 0.0 0.051 11.6 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal ParA PF10609.4 EME82022.1 - 2.5e-36 123.4 0.1 4.5e-36 122.5 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EME82022.1 - 3.4e-16 59.2 0.0 5.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EME82022.1 - 4e-09 35.9 0.0 3.4e-08 32.9 0.0 1.9 1 1 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EME82022.1 - 2.9e-07 29.8 0.2 3.9e-05 22.8 0.5 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EME82022.1 - 1e-06 28.8 0.0 4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 EME82022.1 - 0.00017 21.2 0.6 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EME82022.1 - 0.00053 18.8 0.4 0.00077 18.3 0.3 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EME82022.1 - 0.0028 17.0 0.7 0.0041 16.5 0.1 1.5 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 EME82022.1 - 0.0041 16.5 0.3 0.007 15.7 0.2 1.5 1 1 0 1 1 1 1 YhjQ protein APS_kinase PF01583.15 EME82022.1 - 0.031 13.9 0.1 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 EME82022.1 - 0.038 13.4 0.1 0.73 9.2 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 EME82022.1 - 0.064 12.4 1.4 0.096 11.8 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PQ-loop PF04193.9 EME82023.1 - 5e-37 125.2 14.3 4.6e-19 67.7 1.1 2.7 3 0 0 3 3 3 2 PQ loop repeat SpoIIIAH PF12685.2 EME82023.1 - 0.47 9.9 2.8 13 5.2 0.0 2.4 2 1 0 2 2 2 0 SpoIIIAH-like protein Strep_his_triad PF04270.8 EME82024.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Streptococcal histidine triad protein Herpes_capsid PF06112.6 EME82024.1 - 0.076 13.0 4.6 0.085 12.8 3.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ACP_syn_III_C PF08541.5 EME82025.1 - 0.17 11.9 2.1 1.3 9.1 0.7 2.1 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MTHFR PF02219.12 EME82027.1 - 5.3e-101 337.4 0.0 8.3e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Glyco_hydro_2 PF00703.16 EME82028.1 - 1.6e-13 51.0 1.4 1.8e-11 44.4 0.0 3.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EME82028.1 - 4.5e-07 29.5 0.2 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Phage-tail_1 PF09097.5 EME82028.1 - 0.054 13.0 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 FixG_C PF11614.3 EME82028.1 - 0.067 13.3 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase COX5A PF02284.11 EME82029.1 - 6.6e-40 135.4 0.1 6.6e-40 135.4 0.1 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va DUF1115 PF06544.7 EME82030.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Aldedh PF00171.17 EME82031.1 - 2.1e-135 451.6 7.3 2.3e-98 329.5 1.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 EME82031.1 - 6.9e-05 21.7 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EME82031.1 - 0.074 12.2 0.1 8.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) NadA PF02445.11 EME82031.1 - 0.08 11.7 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein DHHA2 PF02833.9 EME82032.1 - 1.9e-27 95.9 0.0 3.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EME82032.1 - 9.9e-06 25.2 0.3 0.00012 21.7 0.2 2.4 1 1 0 1 1 1 1 DHH family SGS PF05002.10 EME82033.1 - 1.3e-26 92.1 1.6 1.3e-25 88.9 0.0 2.9 3 0 0 3 3 3 1 SGS domain CS PF04969.11 EME82033.1 - 7.9e-14 51.9 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EME82033.1 - 2.6e-11 43.0 3.2 1.7e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 EME82033.1 - 1.3e-09 38.4 1.7 0.0011 19.6 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME82033.1 - 2.1e-06 27.9 0.9 0.089 13.1 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME82033.1 - 3e-06 26.6 1.1 0.12 12.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME82033.1 - 9.7e-05 22.2 0.2 0.014 15.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME82033.1 - 0.00044 20.6 0.5 2.5 8.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EME82033.1 - 0.0045 17.1 4.0 0.05 13.7 0.2 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3275 PF11679.3 EME82033.1 - 0.041 13.5 3.7 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) TPR_4 PF07721.9 EME82033.1 - 5.1 7.8 7.6 1.7 9.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Scramblase PF03803.10 EME82034.1 - 1.8e-51 174.3 0.2 2.2e-27 95.6 0.0 3.0 2 1 0 2 2 2 2 Scramblase tRNA_int_endo PF01974.12 EME82035.1 - 7.8e-16 57.6 0.4 1.3e-15 56.9 0.3 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EME82035.1 - 1.4e-08 34.1 0.1 0.00012 21.4 0.0 2.6 3 0 0 3 3 3 2 tRNA intron endonuclease, N-terminal domain Ank_2 PF12796.2 EME82036.1 - 3.2e-33 113.9 0.6 4e-14 52.7 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EME82036.1 - 4.5e-29 98.7 4.7 6.5e-06 25.6 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EME82036.1 - 7.3e-17 61.0 1.8 6e-05 23.1 0.0 5.7 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME82036.1 - 5e-16 58.7 0.1 8.9e-05 22.8 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME82036.1 - 2.8e-12 45.6 0.0 0.58 10.5 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.7 EME82037.1 - 5.7e-09 35.8 1.0 6.2e-08 32.4 0.7 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME82037.1 - 1.7e-06 28.1 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EME82037.1 - 0.0016 17.3 0.0 0.0037 16.1 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EME82037.1 - 0.016 15.3 0.0 0.055 13.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EME82037.1 - 0.029 14.5 0.1 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Nol1_Nop2_Fmu PF01189.12 EME82038.1 - 7.2e-97 324.1 0.0 1.2e-96 323.4 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EME82038.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME82038.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Coiled PF05710.7 EME82039.1 - 0.036 14.5 0.3 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Coiled coil DUF4475 PF14753.1 EME82039.1 - 0.055 12.9 1.5 0.069 12.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) Herpes_UL52 PF03121.10 EME82039.1 - 6.3 6.6 9.2 17 5.2 3.1 2.6 2 1 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase GATase_5 PF13507.1 EME82040.1 - 2.5e-96 321.5 0.0 3.8e-96 320.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EME82040.1 - 4.7e-40 137.1 0.7 1.5e-19 70.5 0.0 3.0 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EME82040.1 - 7.1e-25 87.0 0.2 2.9e-24 85.1 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain B56 PF01603.15 EME82041.1 - 5e-173 575.4 6.5 5.9e-173 575.1 4.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 EME82041.1 - 0.15 11.8 0.2 0.37 10.6 0.0 1.6 2 0 0 2 2 2 0 Dynamin family SOG2 PF10428.4 EME82041.1 - 3.3 6.2 7.0 1.2 7.7 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Tau95 PF09734.4 EME82042.1 - 9.8e-55 186.0 0.0 1.3e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Cu_amine_oxid PF01179.15 EME82043.1 - 1.5e-167 557.4 0.0 1.9e-167 557.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EME82043.1 - 2.9e-17 62.5 0.0 1.6e-16 60.2 0.0 2.2 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EME82043.1 - 5.7e-13 48.7 0.0 1e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RNA_GG_bind PF10258.4 EME82044.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 PHAX RNA-binding domain Pkinase PF00069.20 EME82046.1 - 6.1e-65 218.9 0.0 8.9e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82046.1 - 4.2e-29 101.4 0.0 6.2e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82046.1 - 2.1e-05 23.6 0.0 6.2e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EME82046.1 - 7.5e-05 21.8 0.0 0.0002 20.4 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EME82046.1 - 0.0031 16.8 0.0 0.0068 15.7 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL rve PF00665.21 EME82046.1 - 0.08 13.0 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain AA_kinase PF00696.23 EME82047.1 - 3.2e-39 134.9 0.1 5.2e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family Hid1 PF12722.2 EME82050.1 - 6.8e-145 484.0 0.1 2.7e-144 482.0 0.1 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EME82050.1 - 9.7e-60 202.4 0.0 1.6e-59 201.7 0.0 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein AA_permease_2 PF13520.1 EME82052.1 - 7.6e-26 90.6 14.3 9.2e-26 90.3 9.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME82052.1 - 5.3e-12 44.8 16.4 6.6e-12 44.5 11.4 1.1 1 0 0 1 1 1 1 Amino acid permease PIG-P PF08510.7 EME82052.1 - 0.83 9.3 4.4 0.35 10.5 0.1 2.2 1 1 1 2 2 2 0 PIG-P DUF656 PF04920.7 EME82052.1 - 2 8.1 5.1 0.38 10.4 0.1 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF656) LysM PF01476.15 EME82053.1 - 0.00022 21.0 0.0 0.047 13.5 0.0 2.4 2 0 0 2 2 2 2 LysM domain Caps_synth PF05704.7 EME82054.1 - 5.9e-11 42.0 0.2 1.8e-10 40.4 0.1 1.7 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EME82054.1 - 0.00014 22.2 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cut12 PF11500.3 EME82055.1 - 3.4e-21 75.5 20.1 3.4e-21 75.5 13.9 2.4 2 1 0 2 2 2 1 Spindle pole body formation-associated protein SspO PF08175.7 EME82055.1 - 0.007 16.6 0.1 0.028 14.7 0.1 2.1 1 0 0 1 1 1 1 Small acid-soluble spore protein O family IncA PF04156.9 EME82055.1 - 0.008 15.7 10.7 0.008 15.7 7.4 1.8 2 0 0 2 2 2 1 IncA protein DUF2570 PF10828.3 EME82055.1 - 0.17 11.5 9.5 0.023 14.2 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Syntaxin_2 PF14523.1 EME82055.1 - 1 9.4 8.5 1.2 9.1 4.7 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF4613 PF15390.1 EME82055.1 - 2.8 6.0 8.2 4.6 5.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4446 PF14584.1 EME82055.1 - 4.6 7.0 7.1 11 5.8 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) RNase_H2-Ydr279 PF09468.5 EME82056.1 - 0.0025 17.0 2.0 0.0034 16.6 1.4 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Nop14 PF04147.7 EME82056.1 - 0.0036 15.3 7.3 0.0039 15.2 5.0 1.0 1 0 0 1 1 1 1 Nop14-like family SR-25 PF10500.4 EME82056.1 - 0.07 12.5 16.9 0.11 11.9 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_DNAp_acc PF04929.7 EME82056.1 - 0.11 11.3 5.4 0.16 10.9 3.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor YL1 PF05764.8 EME82056.1 - 0.13 11.8 18.0 0.18 11.3 12.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Tim54 PF11711.3 EME82056.1 - 0.21 10.1 6.4 0.29 9.6 4.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 EME82056.1 - 1.1 7.1 12.2 1.4 6.8 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4603 PF15376.1 EME82056.1 - 1.6 5.8 9.5 2.1 5.4 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RR_TM4-6 PF06459.7 EME82056.1 - 1.9 8.3 8.0 2.7 7.8 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 EME82056.1 - 2.5 7.0 3.5 3.5 6.5 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MIP-T3 PF10243.4 EME82056.1 - 5.6 5.3 17.9 7.6 4.8 12.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sigma70_ner PF04546.8 EME82056.1 - 5.9 6.4 10.8 8.8 5.8 7.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 EME82056.1 - 6 6.1 14.2 9.6 5.4 9.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) NAAA-beta PF15508.1 EME82057.1 - 2.5e-20 72.6 0.0 4.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Lactamase_B_2 PF12706.2 EME82064.1 - 6.3e-38 130.2 0.1 8.4e-38 129.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME82064.1 - 4.2e-15 55.8 0.0 8.3e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME82064.1 - 0.008 15.8 0.3 0.57 9.7 0.1 2.5 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily AAA_11 PF13086.1 EME82065.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.8 EME82066.1 - 8.5e-31 107.1 0.0 8.5e-31 107.1 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EME82066.1 - 2.4e-11 42.9 0.0 3.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EME82066.1 - 4.4e-05 23.2 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EME82066.1 - 0.054 13.7 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Cluap1 PF10234.4 EME82067.1 - 0.38 9.9 4.6 0.54 9.4 3.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 IncA PF04156.9 EME82067.1 - 3.5 7.1 4.6 6.8 6.2 3.2 1.4 1 0 0 1 1 1 0 IncA protein HET PF06985.6 EME82068.1 - 2.4e-21 76.3 9.1 4.8e-18 65.6 2.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Tim17 PF02466.14 EME82070.1 - 6.4e-49 165.2 10.8 7.4e-49 165.0 7.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EME82070.1 - 0.012 15.1 1.3 0.012 15.1 0.9 2.8 4 0 0 4 4 4 0 Glycine zipper DUF543 PF04418.7 EME82070.1 - 0.2 11.6 5.0 0.43 10.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4048 PF13257.1 EME82071.1 - 7.1e-29 101.1 15.9 7.1e-29 101.1 11.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4048) IncA PF04156.9 EME82071.1 - 0.078 12.5 1.9 0.15 11.6 1.3 1.4 1 0 0 1 1 1 0 IncA protein GrpE PF01025.14 EME82071.1 - 0.12 11.8 1.3 0.21 11.0 0.9 1.3 1 0 0 1 1 1 0 GrpE zf-GRF PF06839.7 EME82072.1 - 0.0015 18.4 10.5 0.019 14.9 2.6 2.6 3 0 0 3 3 3 2 GRF zinc finger Lar_restr_allev PF14354.1 EME82072.1 - 0.012 15.9 2.7 0.012 15.9 1.9 3.0 2 2 1 3 3 3 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EME82072.1 - 1.1 9.5 17.2 0.88 9.8 2.7 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2 PF00096.21 EME82074.1 - 2.9e-07 30.4 16.1 0.00029 20.9 2.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME82074.1 - 3.2e-07 30.3 1.0 3.2e-07 30.3 0.7 3.6 3 1 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.13 EME82074.1 - 3.1e-06 26.9 7.6 3.1e-06 26.9 5.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EME82074.1 - 2e-05 24.5 13.6 0.0049 17.1 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger DUF2156 PF09924.4 EME82074.1 - 0.064 12.0 0.1 0.15 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) Vps39_2 PF10367.4 EME82074.1 - 0.34 11.1 8.8 0.13 12.4 0.5 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Ctr PF04145.10 EME82076.1 - 0.011 15.7 5.6 0.074 13.0 0.1 2.9 2 1 0 2 2 2 0 Ctr copper transporter family DUF4010 PF13194.1 EME82076.1 - 0.024 13.9 1.4 0.062 12.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) DUF1345 PF07077.6 EME82076.1 - 0.06 12.8 1.0 0.66 9.4 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) SpoIIIAH PF12685.2 EME82076.1 - 0.14 11.6 2.6 0.26 10.7 0.1 2.4 3 0 0 3 3 3 0 SpoIIIAH-like protein OAD_gamma PF04277.8 EME82076.1 - 0.26 11.6 2.7 3.7 7.9 0.1 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF202 PF02656.10 EME82076.1 - 0.47 10.6 5.0 0.77 10.0 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) FAT PF02259.18 EME82077.1 - 3.3e-75 253.2 15.3 1.3e-74 251.2 6.1 3.0 3 0 0 3 3 3 2 FAT domain PI3_PI4_kinase PF00454.22 EME82077.1 - 2.8e-23 82.6 0.4 7.5e-23 81.2 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EME82077.1 - 1.5e-08 33.8 0.2 3.9e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.1 EME82077.1 - 0.048 13.4 0.8 18 5.4 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME82077.1 - 0.14 11.7 3.8 9.1 6.0 0.1 3.6 3 0 0 3 3 3 0 TPR repeat SET PF00856.23 EME82078.1 - 5.1e-14 52.8 0.0 1.5e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 SET domain TPR_11 PF13414.1 EME82078.1 - 3e-09 36.3 0.8 3e-09 36.3 0.6 3.2 4 1 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 EME82078.1 - 4.1e-06 26.1 3.3 4.2e-05 22.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME82078.1 - 4.5e-06 26.1 11.2 0.00013 21.6 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME82078.1 - 0.0036 17.2 1.2 0.0036 17.2 0.8 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME82078.1 - 0.075 12.8 0.0 0.34 10.7 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 EME82078.1 - 5.1 7.0 11.6 0.12 12.2 0.3 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 EME82080.1 - 5e-33 114.2 35.5 5e-33 114.2 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NMO PF03060.10 EME82081.1 - 5.4e-60 203.2 0.0 1.3e-37 129.6 0.0 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EME82081.1 - 1.3e-10 40.7 0.0 4.7e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EME82081.1 - 0.053 12.3 0.1 0.087 11.6 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Sugar_tr PF00083.19 EME82082.1 - 1.4e-90 304.0 21.1 1.8e-90 303.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82082.1 - 7.1e-27 94.0 31.1 1.1e-26 93.4 21.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ceramidase PF05875.7 EME82082.1 - 0.069 12.2 1.5 0.11 11.6 1.1 1.3 1 0 0 1 1 1 0 Ceramidase SnoaL_4 PF13577.1 EME82083.1 - 5.1e-12 45.8 0.0 7.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EME82083.1 - 0.076 13.0 0.1 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain Cyclase PF04199.8 EME82084.1 - 3e-16 59.5 0.1 5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Hexapep PF00132.19 EME82084.1 - 0.095 12.2 0.4 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Acetyltransf_1 PF00583.19 EME82085.1 - 7.5e-11 41.9 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME82085.1 - 1.5e-09 37.8 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME82085.1 - 4.3e-07 30.0 0.0 5.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME82085.1 - 0.00037 20.4 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME82085.1 - 0.0044 16.9 0.0 0.0058 16.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME82085.1 - 0.015 15.1 0.1 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME82085.1 - 0.028 14.5 0.0 0.039 14.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_22 PF03901.12 EME82088.1 - 5.6e-60 203.5 18.4 7.1e-60 203.1 12.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 EME82089.1 - 6e-39 131.9 2.3 1.1e-38 131.1 1.6 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EME82089.1 - 8.4e-21 73.8 0.2 1.8e-20 72.7 0.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EME82089.1 - 0.065 13.2 1.2 0.073 13.0 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ribosomal_L2_C PF03947.13 EME82090.1 - 1.1e-37 128.7 3.6 1.1e-37 128.7 2.5 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EME82090.1 - 5.6e-13 48.6 0.2 1.2e-12 47.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain WHIM2 PF15613.1 EME82091.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF605 PF04652.11 EME82092.1 - 8.2 5.7 13.2 9.4 5.5 9.1 1.0 1 0 0 1 1 1 0 Vta1 like Spo12 PF05032.7 EME82093.1 - 1.1e-07 31.2 0.1 2.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Spo12 family DUF1425 PF07233.7 EME82093.1 - 0.12 11.9 0.2 4.3 6.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1425) Ribosomal_L39 PF00832.15 EME82094.1 - 3.8e-22 77.4 9.0 4.2e-22 77.3 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EME82094.1 - 0.1 12.1 0.7 0.11 12.0 0.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) CN_hydrolase PF00795.17 EME82095.1 - 1.3e-18 66.9 0.0 2.7e-18 65.9 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DC_STAMP PF07782.8 EME82095.1 - 0.036 13.6 0.1 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 DC-STAMP-like protein Xan_ur_permease PF00860.15 EME82096.1 - 0.0011 17.4 0.6 0.0015 17.0 0.4 1.0 1 0 0 1 1 1 1 Permease family Phage_holin_2 PF04550.7 EME82096.1 - 0.055 13.5 0.1 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Phage holin family 2 PRRSV_2b PF07069.6 EME82096.1 - 0.33 11.2 3.5 0.41 10.9 0.1 2.5 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b Abhydrolase_6 PF12697.2 EME82097.1 - 8e-28 97.8 0.0 9.3e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME82097.1 - 2.7e-10 40.1 0.0 6.4e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME82097.1 - 0.0011 18.6 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EME82097.1 - 0.027 14.0 0.1 2.2 7.8 0.2 2.2 1 1 1 2 2 2 0 PGAP1-like protein DUF900 PF05990.7 EME82097.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Synapsin PF02078.11 EME82097.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Synapsin, N-terminal domain ApbA PF02558.11 EME82098.1 - 2.8e-29 101.5 0.2 3.6e-29 101.1 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EME82098.1 - 5.7e-27 94.1 0.0 1.1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 EME82098.1 - 0.0091 15.7 0.1 1.1 8.9 0.3 2.3 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EME82098.1 - 0.065 13.6 1.4 0.21 12.0 0.9 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EME82098.1 - 0.3 10.9 2.3 0.69 9.7 1.0 2.0 3 0 0 3 3 3 0 ThiF family ABM PF03992.11 EME82099.1 - 4.8e-09 36.1 1.5 1.4e-05 25.0 0.2 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HgmA PF04209.8 EME82100.1 - 1.2e-116 389.6 0.0 1.5e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TGS PF02824.16 EME82101.1 - 3.3e-20 71.6 0.1 5.8e-20 70.8 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EME82101.1 - 1.1e-18 67.2 0.1 2.2e-18 66.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME82101.1 - 3.1e-13 49.3 0.0 5.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EME82101.1 - 0.0029 18.0 0.1 0.0086 16.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EME82101.1 - 0.0038 17.0 0.3 1.6 8.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EME82101.1 - 0.031 13.0 0.3 0.083 11.6 0.1 1.8 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 EME82101.1 - 0.056 12.2 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family MBOAT_2 PF13813.1 EME82102.1 - 9.6e-17 60.8 1.3 9.6e-17 60.8 0.9 2.7 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EME82103.1 - 2.4e-44 151.5 26.7 9.9e-42 142.8 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME82103.1 - 6.7e-10 38.1 5.1 6.7e-10 38.1 3.6 2.3 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EME82103.1 - 1.1e-09 37.1 10.2 0.00021 19.8 0.2 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EME82103.1 - 0.00014 20.2 1.5 0.00021 19.6 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EME82103.1 - 0.0019 17.9 0.8 0.45 10.3 0.0 3.0 2 0 0 2 2 2 1 MFS_1 like family YiaAB PF05360.9 EME82103.1 - 0.017 14.6 1.3 0.069 12.7 0.9 2.1 1 0 0 1 1 1 0 yiaA/B two helix domain LacY_symp PF01306.14 EME82103.1 - 0.019 13.5 5.3 0.014 13.9 1.1 2.1 1 1 1 2 2 2 0 LacY proton/sugar symporter RskA PF10099.4 EME82104.1 - 0.071 12.8 0.5 0.074 12.7 0.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA NR_Repeat PF14046.1 EME82104.1 - 0.14 11.9 0.5 0.14 11.9 0.3 1.6 2 0 0 2 2 2 0 Nuclear receptor repeat Saccharop_dh PF03435.13 EME82105.1 - 3.1e-118 395.1 0.0 3.6e-118 394.9 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EME82105.1 - 2.7e-06 27.5 0.3 6e-06 26.3 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EME82105.1 - 4.7e-06 26.7 1.1 7.7e-06 26.0 0.8 1.3 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 EME82105.1 - 0.00019 20.8 0.1 0.00042 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EME82105.1 - 0.0034 17.7 0.3 0.0073 16.7 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME82105.1 - 0.027 14.4 0.8 0.049 13.6 0.6 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EME82105.1 - 0.032 14.4 0.3 0.077 13.2 0.2 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 EME82105.1 - 0.061 13.1 0.2 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) p450 PF00067.17 EME82106.1 - 2.1e-36 125.4 0.0 2.4e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.15 EME82108.1 - 3.8e-15 55.5 0.0 6.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Transp_cyt_pur PF02133.10 EME82109.1 - 8e-81 271.8 39.7 9.6e-81 271.5 27.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF872 PF05915.7 EME82109.1 - 0.069 13.0 3.3 13 5.7 0.0 3.8 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) DUF2583 PF10762.4 EME82109.1 - 0.18 11.9 7.4 0.26 11.4 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) DKCLD PF08068.7 EME82110.1 - 3e-29 100.7 0.4 3.2e-28 97.4 0.0 2.8 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 EME82110.1 - 2.6e-24 86.0 3.9 2.9e-22 79.4 0.2 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EME82110.1 - 4.5e-20 71.1 1.2 9.6e-20 70.1 0.8 1.6 1 0 0 1 1 1 1 PUA domain Pyr_redox_2 PF07992.9 EME82110.1 - 0.051 13.4 2.0 0.13 12.1 1.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Med19 PF10278.4 EME82110.1 - 7.2 6.2 15.8 18 4.9 11.0 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Transglut_core PF01841.14 EME82112.1 - 2.1e-10 40.8 0.3 4.8e-10 39.6 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EME82112.1 - 4.1e-06 26.1 0.0 9.7e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME82112.1 - 4.8e-05 22.6 1.2 5.4e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EME82112.1 - 0.00067 19.1 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RNA_pol_L_2 PF13656.1 EME82113.1 - 3.9e-30 103.0 0.0 4.9e-30 102.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EME82113.1 - 5.5e-09 35.0 0.0 7.4e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SNF2_N PF00176.18 EME82114.1 - 4.3e-85 285.1 2.3 4.3e-85 285.1 1.6 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EME82114.1 - 2.9e-25 87.9 0.3 1.5e-24 85.6 0.2 2.3 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EME82114.1 - 4.6e-20 71.2 0.0 2.1e-18 65.9 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EME82114.1 - 1.9e-17 63.1 1.3 1.9e-17 63.1 0.9 3.1 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EME82114.1 - 3.2e-14 52.4 11.3 3.2e-14 52.4 7.8 3.0 2 0 0 2 2 2 1 HSA IGPD PF00475.13 EME82115.1 - 1.6e-43 148.0 0.5 2.2e-43 147.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HCMVantigenic_N PF12154.3 EME82115.1 - 1.8 8.5 7.1 18 5.3 3.0 2.5 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV tRNA-synt_1e PF01406.14 EME82117.1 - 4.1e-113 377.4 0.1 6.9e-113 376.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EME82117.1 - 8.2e-06 24.7 1.2 0.22 10.1 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 EME82117.1 - 0.035 12.7 0.0 0.035 12.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.6 EME82117.1 - 0.063 13.5 2.4 0.07 13.3 0.0 2.3 2 0 0 2 2 2 0 DALR domain MFS_1 PF07690.11 EME82120.1 - 1.2e-34 119.6 28.7 2e-34 118.8 19.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1691 PF07950.6 EME82120.1 - 0.015 15.2 0.3 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) DUF485 PF04341.7 EME82120.1 - 0.041 13.6 0.1 0.041 13.6 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function, DUF485 DUF1228 PF06779.9 EME82120.1 - 0.049 13.6 0.1 0.049 13.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) zf-MYND PF01753.13 EME82121.1 - 0.022 14.6 7.1 0.042 13.7 4.9 1.5 1 0 0 1 1 1 0 MYND finger Piwi PF02171.12 EME82122.1 - 4.4e-66 222.8 0.0 4.9e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Pkinase PF00069.20 EME82123.1 - 1.3e-24 86.7 0.0 1.7e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82123.1 - 0.00077 18.6 0.0 0.0069 15.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_6 PF12697.2 EME82126.1 - 1.5e-22 80.6 0.0 1.8e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME82126.1 - 1.1e-08 34.9 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME82126.1 - 0.0098 15.7 0.0 0.029 14.2 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase PIG-P PF08510.7 EME82128.1 - 2.2e-44 150.0 0.5 2.9e-44 149.7 0.3 1.1 1 0 0 1 1 1 1 PIG-P Pex14_N PF04695.8 EME82128.1 - 0.0097 15.9 0.2 0.77 9.7 0.1 2.3 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DPM2 PF07297.7 EME82128.1 - 4.1 7.7 10.1 6.6 7.0 7.0 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Cu-oxidase_3 PF07732.10 EME82129.1 - 1e-43 147.8 0.4 1e-43 147.8 0.3 3.2 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EME82129.1 - 1e-32 113.2 0.1 2.3e-30 105.6 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME82129.1 - 4.4e-32 110.4 10.0 5.7e-28 97.1 1.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase SSB PF00436.20 EME82132.1 - 2.9e-12 46.3 0.0 3.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family Nucleoplasmin PF03066.10 EME82133.1 - 0.69 9.4 10.0 1.1 8.8 7.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EME82133.1 - 8.9 6.6 15.0 16 5.7 10.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_transf_25 PF01755.12 EME82136.1 - 0.024 14.3 0.0 0.71 9.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Pkinase PF00069.20 EME82137.1 - 3.5e-62 209.8 0.0 5.1e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82137.1 - 6.5e-27 94.2 0.0 9e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82137.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF4551 PF15087.1 EME82138.1 - 0.14 10.5 2.3 0.14 10.4 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dysbindin PF04440.11 EME82138.1 - 0.27 10.9 2.8 0.42 10.3 1.9 1.3 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Pol_alpha_B_N PF08418.5 EME82138.1 - 0.4 10.1 3.8 0.41 10.1 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CoA_transf_3 PF02515.12 EME82139.1 - 6.3e-51 172.3 0.0 9e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Sgf11 PF08209.6 EME82140.1 - 0.078 12.3 0.6 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF1688 PF07958.6 EME82141.1 - 7.1e-181 601.3 0.0 8.1e-181 601.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SET PF00856.23 EME82142.1 - 5.7e-11 42.9 0.0 6.6e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 SET domain Sdh_cyt PF01127.17 EME82143.1 - 1.4e-20 73.3 5.0 1.9e-20 72.8 3.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.13 EME82144.1 - 4.2e-15 55.3 0.8 8.1e-15 54.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Paramyxo_C PF01692.13 EME82144.1 - 0.44 10.1 7.4 0.92 9.0 0.5 2.4 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c HR1 PF02185.11 EME82144.1 - 0.52 10.0 3.1 13 5.6 0.3 2.7 2 0 0 2 2 2 0 Hr1 repeat zf-MYND PF01753.13 EME82146.1 - 0.028 14.2 9.4 0.061 13.2 6.5 1.6 1 0 0 1 1 1 0 MYND finger AA_permease PF00324.16 EME82147.1 - 3.2e-117 391.8 40.7 4.1e-117 391.4 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME82147.1 - 5.8e-25 87.7 43.6 7.9e-25 87.2 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 EME82147.1 - 0.16 12.3 3.7 23 5.4 1.1 3.1 2 1 1 3 3 3 0 Early E3 14.5 kDa protein NUDIX PF00293.23 EME82148.1 - 3.9e-13 49.2 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain TRAPP PF04051.11 EME82149.1 - 2.3e-41 140.8 0.0 2.6e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2378 PF09536.5 EME82149.1 - 0.052 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) Ldh_1_N PF00056.18 EME82150.1 - 3.9e-44 149.9 0.1 5.6e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EME82150.1 - 3.2e-41 140.9 0.0 4.3e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EME82150.1 - 0.0029 16.3 0.0 0.0046 15.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EME82150.1 - 0.027 13.7 0.2 0.46 9.7 0.1 2.1 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.1 EME82150.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Nitroreductase PF00881.19 EME82151.1 - 8.2e-09 35.4 0.0 3.6e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Nitroreductase family CBFD_NFYB_HMF PF00808.18 EME82152.1 - 5.6e-20 71.1 0.6 7.3e-20 70.8 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME82152.1 - 1.1e-11 44.7 0.1 1.5e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EME82152.1 - 0.0083 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X GMC_oxred_N PF00732.14 EME82153.1 - 1.3e-26 93.4 0.0 2.6e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME82153.1 - 1.2e-24 87.2 0.1 3e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase ACT_7 PF13840.1 EME82153.1 - 1.7e-24 85.0 0.0 6.4e-15 54.4 0.0 3.4 3 0 0 3 3 3 2 ACT domain DAO PF01266.19 EME82153.1 - 1e-10 41.0 0.1 0.00025 20.0 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME82153.1 - 1.1e-07 31.0 0.1 0.0013 17.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.13 EME82153.1 - 1.1e-05 24.9 2.3 2.7e-05 23.7 1.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Pyr_redox_3 PF13738.1 EME82153.1 - 1.2e-05 25.4 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME82153.1 - 0.00012 22.0 0.0 0.00069 19.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME82153.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EME82153.1 - 0.0015 17.1 0.0 0.071 11.5 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EME82153.1 - 0.013 14.5 0.3 0.052 12.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EME82153.1 - 0.021 15.2 0.0 3.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EME82154.1 - 7.3e-14 52.0 0.1 2.1e-13 50.5 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME82154.1 - 8.1e-06 25.7 0.0 0.0001 22.1 0.0 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME82154.1 - 0.00021 20.8 0.1 0.00039 19.9 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME82154.1 - 0.00043 20.0 0.5 0.013 15.1 0.4 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME82154.1 - 0.0011 18.9 0.1 0.0028 17.7 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EME82154.1 - 0.022 14.5 0.1 0.056 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SOR_SNZ PF01680.12 EME82155.1 - 4.4e-109 362.9 8.3 6e-109 362.4 5.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EME82155.1 - 4.6e-07 29.1 11.4 5.1e-06 25.7 0.8 2.6 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 EME82155.1 - 0.00018 20.6 0.2 0.00061 18.9 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 EME82155.1 - 0.00028 19.8 0.9 0.014 14.2 0.1 2.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EME82155.1 - 0.0004 19.7 0.6 0.06 12.5 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 EME82155.1 - 0.00049 19.1 0.6 0.004 16.1 0.0 2.4 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EME82155.1 - 0.002 17.0 0.1 0.0085 14.9 0.0 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EME82155.1 - 0.011 14.8 0.5 0.011 14.8 0.3 2.2 2 1 0 2 2 2 0 Nitronate monooxygenase MxiH PF09392.5 EME82155.1 - 0.017 15.6 0.1 0.1 13.2 0.1 2.2 1 1 0 1 1 1 0 Type III secretion needle MxiH like TMP-TENI PF02581.12 EME82155.1 - 0.025 13.7 0.8 0.12 11.5 0.1 2.3 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI OMPdecase PF00215.19 EME82155.1 - 0.029 13.7 1.5 0.3 10.4 1.1 2.2 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2984 PF11203.3 EME82155.1 - 0.67 10.1 3.6 0.41 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) P5-ATPase PF12409.3 EME82156.1 - 2.8e-36 123.9 0.0 5.8e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EME82156.1 - 3.7e-30 105.5 0.0 8.4e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EME82156.1 - 5.5e-27 94.2 0.2 2.4e-26 92.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EME82156.1 - 5.2e-16 59.7 0.0 1.7e-11 44.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EME82156.1 - 3.1e-07 30.0 5.4 3.1e-07 30.0 3.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EME82156.1 - 0.0011 18.5 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME82156.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit HET PF06985.6 EME82157.1 - 4.7e-17 62.4 5.5 5.7e-17 62.1 2.0 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) COPI_C PF06957.6 EME82158.1 - 5.7 5.3 6.4 6.6 5.1 4.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Fungal_trans PF04082.13 EME82159.1 - 1.5e-07 30.5 0.8 4.4e-07 29.0 0.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME82159.1 - 2.3e-07 30.6 5.5 4.2e-07 29.7 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L5_C PF00673.16 EME82160.1 - 6.1e-26 89.9 0.0 1.2e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EME82160.1 - 4.5e-05 23.1 0.0 8.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.1 EME82161.1 - 2.9e-62 210.7 0.0 8.2e-62 209.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_12 PF13424.1 EME82162.1 - 0.00063 19.6 2.6 0.00063 19.6 1.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat GatB_Yqey PF02637.13 EME82162.1 - 0.19 11.4 4.8 0.49 10.1 3.4 1.7 1 0 0 1 1 1 0 GatB domain YfdX PF10938.3 EME82162.1 - 0.29 10.7 0.0 0.29 10.7 0.0 3.4 3 2 0 3 3 3 0 YfdX protein DUF874 PF05917.6 EME82162.1 - 0.38 9.5 8.5 0.64 8.8 5.9 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) TPR_2 PF07719.12 EME82162.1 - 0.54 10.3 13.6 5.6 7.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Mer2 PF09074.5 EME82162.1 - 0.56 10.1 11.1 2 8.2 7.7 1.9 1 1 0 1 1 1 0 Mer2 TPR_16 PF13432.1 EME82162.1 - 2.4 8.9 16.6 5.2 7.8 2.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME82162.1 - 2.6 7.7 13.8 0.42 10.2 0.1 3.7 4 1 0 4 4 4 0 TPR repeat DUF3802 PF12290.3 EME82162.1 - 4.3 7.6 7.9 1.6 9.0 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) DUF2664 PF10867.3 EME82162.1 - 6.4 7.4 13.1 12 6.5 4.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) XPA_C PF05181.7 EME82163.1 - 1.6e-28 97.9 3.5 1.6e-28 97.9 2.4 1.8 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EME82163.1 - 1.8 8.2 12.3 0.31 10.7 4.9 2.2 2 0 0 2 2 2 0 XPA protein N-terminal TF_Zn_Ribbon PF08271.7 EME82163.1 - 3.4 7.0 9.1 0.91 8.8 0.2 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding YhfH PF14149.1 EME82163.1 - 8 6.3 13.7 0.22 11.3 0.5 2.7 2 1 0 2 2 2 0 YhfH-like protein Lyase_8_C PF02884.12 EME82164.1 - 0.031 14.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide lyase family 8, C-terminal beta-sandwich domain DNA_pol3_a_NII PF11490.3 EME82165.1 - 0.71 9.5 2.8 2.9 7.5 1.3 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Pyr_redox_2 PF07992.9 EME82166.1 - 3.1e-11 43.5 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME82166.1 - 1.2e-05 25.4 0.1 0.021 14.8 0.0 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME82166.1 - 2.4e-05 24.6 0.1 0.00018 21.8 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME82166.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EME82166.1 - 0.11 11.3 0.5 4.4 6.1 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase VEGF_C PF14554.1 EME82167.1 - 1.6 8.5 6.8 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 VEGF heparin-binding domain HeLo PF14479.1 EME82168.1 - 0.0025 17.6 0.1 0.0037 17.0 0.1 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF939 PF06081.6 EME82168.1 - 0.14 11.9 0.4 0.65 9.8 0.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) Histone PF00125.19 EME82169.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME82169.1 - 2e-05 24.5 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyco_hydro_31 PF01055.21 EME82171.1 - 2.1e-148 494.8 2.4 3.4e-148 494.1 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME82171.1 - 1.9e-22 78.8 0.2 6e-22 77.2 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like NDK PF00334.14 EME82172.1 - 2.9e-54 182.5 0.0 3.3e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MFS_1 PF07690.11 EME82174.1 - 1.2e-28 99.9 32.4 2.8e-28 98.6 22.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PEMT PF04191.8 EME82174.1 - 0.071 13.2 9.8 1.5 8.9 0.1 3.9 3 0 0 3 3 3 0 Phospholipid methyltransferase GFO_IDH_MocA_C PF02894.12 EME82175.1 - 1.3e-16 60.3 0.4 2.7e-16 59.3 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EME82175.1 - 2.1e-13 50.8 0.0 3.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SNF2_N PF00176.18 EME82177.1 - 1e-61 208.3 0.1 2e-61 207.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME82177.1 - 2.1e-12 46.7 0.0 5.5e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EME82177.1 - 1.2e-08 34.4 5.3 1.2e-08 34.4 3.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EME82177.1 - 2e-06 27.7 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.1 EME82177.1 - 1.6e-05 23.8 0.6 9.1e-05 21.3 0.0 2.3 3 0 0 3 3 3 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_2 PF13923.1 EME82177.1 - 0.00013 21.9 5.2 0.00013 21.9 3.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME82177.1 - 0.0014 18.2 6.5 0.0014 18.2 4.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EME82177.1 - 0.0023 17.7 6.2 0.0023 17.7 4.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EME82177.1 - 0.0029 17.4 5.0 0.0029 17.4 3.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Peptidase_M16 PF00675.15 EME82179.1 - 3.2e-30 104.8 0.9 1.5e-29 102.6 0.6 2.2 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EME82179.1 - 2.5e-29 102.2 0.0 2.1e-21 76.4 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain UCH PF00443.24 EME82180.1 - 6.2e-12 45.1 0.0 8.9e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 EME82180.1 - 3.5e-11 42.6 7.8 5.7e-11 41.9 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.15 EME82180.1 - 3.5e-08 32.6 17.1 6.1e-06 25.6 0.0 4.8 5 0 0 5 5 5 3 MORN repeat MATH PF00917.21 EME82180.1 - 0.00018 21.7 0.1 0.014 15.6 0.1 2.6 1 1 0 1 1 1 1 MATH domain zf-C3HC4_2 PF13923.1 EME82180.1 - 0.00052 19.9 10.3 0.0011 18.9 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.4 EME82180.1 - 0.069 13.1 4.6 0.16 11.9 3.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Prok-RING_4 PF14447.1 EME82180.1 - 0.11 12.0 5.9 0.27 10.8 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 EME82180.1 - 1.2 8.8 9.7 2.4 7.9 6.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EME82180.1 - 5 7.0 8.6 15 5.5 5.9 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 EME82180.1 - 5 6.9 6.7 0.85 9.3 1.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger DS PF01916.12 EME82181.1 - 2.8e-146 486.3 0.0 3.2e-146 486.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EME82181.1 - 0.01 15.0 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Carbamoyltransferase DUF3736 PF12540.3 EME82183.1 - 0.0053 17.0 3.0 0.0091 16.2 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3736) Bac_rhamnosid PF05592.6 EME82185.1 - 9.2e-17 60.4 0.3 1.5e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EME82185.1 - 0.0088 14.7 0.5 0.033 12.8 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF608 Myosin_head PF00063.16 EME82187.1 - 5.1e-242 804.8 0.0 7.9e-242 804.1 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EME82187.1 - 9.7e-35 118.6 3.4 2.9e-34 117.1 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EME82187.1 - 3.8e-11 41.5 27.5 0.00013 21.2 0.1 6.5 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.1 EME82187.1 - 0.001 19.2 0.0 0.0047 17.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain CALCOCO1 PF07888.6 EME82187.1 - 0.0025 16.1 17.8 0.0045 15.3 12.3 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like HlyD PF00529.15 EME82187.1 - 0.0035 16.7 20.6 0.0035 16.7 14.3 1.7 2 0 0 2 2 1 1 HlyD family secretion protein AAA_19 PF13245.1 EME82187.1 - 0.028 14.1 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain TMP_2 PF06791.8 EME82187.1 - 0.035 13.7 5.0 0.069 12.7 3.5 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein Reo_sigmaC PF04582.7 EME82187.1 - 0.13 11.4 3.4 0.3 10.2 2.3 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 EME82187.1 - 0.13 11.4 25.9 0.51 9.5 7.4 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.22 EME82187.1 - 0.15 12.3 2.3 2.6 8.3 0.0 3.2 2 1 0 2 2 2 0 ABC transporter FlaC_arch PF05377.6 EME82187.1 - 0.24 11.3 9.7 0.065 13.1 0.4 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 EME82187.1 - 0.26 10.8 27.0 1.1 8.7 6.9 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 EME82187.1 - 0.92 9.8 18.0 3.8 7.9 4.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4510 PF14971.1 EME82187.1 - 1.2 9.2 13.3 3.2 7.8 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) CENP-F_leu_zip PF10473.4 EME82187.1 - 1.9 8.3 23.7 0.11 12.3 4.4 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EME82187.1 - 3.3 6.5 19.9 11 4.9 13.8 1.9 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EME82187.1 - 5.2 7.1 17.0 12 5.9 3.3 3.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Chitin_bind_3 PF03067.10 EME82188.1 - 0.00018 21.8 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Chitin binding domain Abhydrolase_3 PF07859.8 EME82190.1 - 5.8e-39 133.8 0.0 8.2e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EME82190.1 - 0.006 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.23 EME82190.1 - 0.054 12.2 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Peptidase_S9 PF00326.16 EME82190.1 - 0.066 12.4 0.0 0.26 10.4 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family RRM_5 PF13893.1 EME82191.1 - 2.6e-06 27.1 0.0 5.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME82191.1 - 3.5e-06 26.5 0.0 7.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME82191.1 - 0.00035 20.4 0.2 0.0008 19.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME82191.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EME82191.1 - 0.053 13.2 0.7 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CBM_20 PF00686.14 EME82192.1 - 2.7e-16 58.9 0.0 2.9e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Starch binding domain DnaJ PF00226.26 EME82193.1 - 1.4e-21 75.9 0.1 1.6e-21 75.8 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.20 EME82194.1 - 4.4e-18 65.7 0.0 6.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME82194.1 - 3.2e-09 36.6 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME82194.1 - 8e-07 28.7 0.0 1.5e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME82194.1 - 2e-06 27.9 0.0 4.8e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EME82194.1 - 0.00051 19.8 0.0 0.00071 19.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EME82194.1 - 0.00098 18.4 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EME82194.1 - 0.0012 17.7 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EME82194.1 - 0.018 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EME82194.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_88 PF07470.8 EME82195.1 - 2.3e-14 53.2 1.5 1e-13 51.0 0.4 1.9 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF3431 PF11913.3 EME82196.1 - 2.2e-53 180.9 0.0 2.6e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PSI PF01437.20 EME82198.1 - 5.5e-06 26.4 9.7 8.7e-06 25.7 6.7 1.4 1 0 0 1 1 1 1 Plexin repeat NAP PF00956.13 EME82199.1 - 1.5e-42 145.3 0.6 2e-42 145.0 0.4 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) PerC PF06069.6 EME82199.1 - 0.03 14.3 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 PerC transcriptional activator MCR_D PF02505.9 EME82199.1 - 0.046 13.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D DUF4611 PF15387.1 EME82199.1 - 1.5 9.0 6.8 2.5 8.2 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NmrA PF05368.8 EME82200.1 - 4.2e-63 212.7 0.0 5.2e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME82200.1 - 3.4e-07 30.4 0.0 4.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Drf_FH1 PF06346.7 EME82201.1 - 0.0026 17.2 23.2 0.0034 16.9 16.1 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 Glyco_hydro_92 PF07971.7 EME82202.1 - 1.4e-159 531.9 0.9 1.8e-159 531.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 NAD_binding_10 PF13460.1 EME82203.1 - 2.1e-12 47.4 0.0 1e-11 45.1 0.0 2.2 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EME82203.1 - 1.1e-07 31.3 0.0 5.6e-07 29.0 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family Sigma54_activ_2 PF14532.1 EME82203.1 - 0.0095 15.9 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Epimerase PF01370.16 EME82203.1 - 0.015 14.7 0.0 0.037 13.4 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Radical_SAM PF04055.16 EME82203.1 - 0.023 14.8 0.0 0.073 13.2 0.0 1.8 1 1 1 2 2 2 0 Radical SAM superfamily Fungal_trans_2 PF11951.3 EME82204.1 - 9.2e-20 70.5 1.7 1.6e-11 43.4 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EME82204.1 - 6.6e-05 22.7 10.7 0.00015 21.6 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EME82205.1 - 1.2e-38 132.7 51.3 1.6e-38 132.3 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME82205.1 - 3.4e-22 78.4 47.7 5e-22 77.8 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF267 PF03268.9 EME82205.1 - 0.78 8.5 8.8 4.2 6.1 1.5 2.4 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 Pkinase PF00069.20 EME82206.1 - 1.7e-23 83.0 0.0 2.3e-22 79.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82206.1 - 1e-06 28.0 0.1 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EME82206.1 - 0.078 12.3 0.2 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 RIO1 family CAF1 PF04857.15 EME82207.1 - 3.5e-54 183.8 0.0 5.1e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EME82208.1 - 1.4e-14 53.5 0.4 2.1e-14 52.9 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Mito_carr PF00153.22 EME82211.1 - 3.7e-68 225.2 3.5 3.5e-24 84.3 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein MUG113 PF13455.1 EME82212.1 - 1.3e-26 92.8 5.1 5.7e-26 90.7 2.1 2.3 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EME82212.1 - 1.9e-23 82.7 1.3 5.1e-22 78.1 0.5 2.6 2 0 0 2 2 2 1 T5orf172 domain Peptidase_S28 PF05577.7 EME82213.1 - 7.9e-36 123.5 0.8 2.5e-35 121.8 0.6 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 WD40 PF00400.27 EME82215.1 - 5e-33 111.7 8.2 1.4e-06 27.9 0.0 6.9 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EME82215.1 - 2.2e-05 24.0 1.9 0.00011 21.7 0.5 2.4 1 1 2 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 EME82215.1 - 0.009 15.7 0.1 2.8 7.7 0.0 3.1 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 EME82215.1 - 0.046 13.2 0.5 7 6.3 0.0 3.4 3 1 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.1 EME82215.1 - 0.13 12.5 9.7 3.7 7.9 0.0 4.4 5 1 1 6 6 6 0 PQQ-like domain Septin PF00735.13 EME82216.1 - 7.5e-116 386.0 0.1 7.5e-116 386.0 0.1 1.3 2 0 0 2 2 1 1 Septin MMR_HSR1 PF01926.18 EME82216.1 - 6.6e-07 29.2 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME82216.1 - 9.6e-06 25.1 0.4 0.00013 21.4 0.2 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EME82216.1 - 1.7e-05 24.0 0.0 4.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME82216.1 - 0.0015 18.6 0.4 0.0062 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EME82216.1 - 0.0026 18.2 0.5 0.0088 16.5 0.0 2.3 2 1 0 2 2 1 1 Miro-like protein AAA_24 PF13479.1 EME82216.1 - 0.0034 16.9 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EME82216.1 - 0.0077 15.7 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EME82216.1 - 0.0081 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EME82216.1 - 0.0081 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Pox_A32 PF04665.7 EME82216.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 EME82216.1 - 0.027 13.3 0.0 0.064 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EME82216.1 - 0.034 14.1 0.8 0.32 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 EME82216.1 - 0.045 13.5 7.1 0.54 10.0 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EME82216.1 - 0.05 13.3 0.0 0.05 13.3 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EME82216.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Ras PF00071.17 EME82216.1 - 0.056 12.8 0.4 0.15 11.4 0.3 1.7 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.22 EME82216.1 - 0.057 13.7 0.3 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Myc-LZ PF02344.10 EME82216.1 - 0.063 12.9 7.0 0.22 11.1 0.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain PduV-EutP PF10662.4 EME82216.1 - 0.064 12.7 0.9 2.5 7.5 0.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EME82216.1 - 0.068 12.1 0.8 0.11 11.4 0.5 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Sigma54_activat PF00158.21 EME82216.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Gtr1_RagA PF04670.7 EME82216.1 - 0.095 11.8 0.0 0.24 10.4 0.0 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EME82216.1 - 0.15 11.5 0.6 8.8 5.7 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Atg14 PF10186.4 EME82216.1 - 0.2 10.5 4.2 0.39 9.6 2.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L6e PF01159.14 EME82216.1 - 1.3 9.3 5.5 44 4.3 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e WD40 PF00400.27 EME82217.1 - 2.5e-53 176.1 20.7 2.6e-12 46.1 0.0 12.4 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 EME82217.1 - 1.8e-22 79.3 0.0 2.8e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EME82217.1 - 2.6e-06 27.2 0.1 0.054 13.2 0.0 5.6 6 1 2 8 8 8 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EME82217.1 - 0.0051 14.7 0.0 0.47 8.1 0.0 2.3 2 0 0 2 2 2 2 IKI3 family PfkB PF00294.19 EME82218.1 - 7.7e-53 179.5 4.1 8.8e-53 179.3 2.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Bac_globin PF01152.16 EME82219.1 - 0.018 15.0 0.0 0.041 13.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial-like globin Fer2 PF00111.22 EME82223.1 - 1.5e-14 53.5 1.1 1.9e-14 53.1 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EME82225.1 - 3.3e-12 45.9 0.4 0.029 14.0 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial carrier protein MotA_ExbB PF01618.11 EME82225.1 - 0.014 15.0 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Pkinase PF00069.20 EME82227.1 - 4.6e-63 212.7 0.0 3.1e-38 131.4 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EME82227.1 - 2.8e-38 131.4 0.0 8.4e-19 67.6 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 EME82227.1 - 9.1e-27 93.8 0.8 9.1e-27 93.8 0.5 2.8 2 1 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 EME82227.1 - 1.3e-10 40.8 6.0 1.6e-10 40.5 0.0 3.1 2 1 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EME82227.1 - 5.3e-10 39.1 0.1 1.3e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.1 EME82227.1 - 0.0058 15.6 0.0 3 6.6 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME82227.1 - 0.015 15.0 0.0 0.015 15.0 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Amidohydro_3 PF07969.6 EME82228.1 - 6.2e-33 114.6 0.1 7.7e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family D-aminoacyl_C PF07908.7 EME82228.1 - 5.3e-16 57.6 0.5 1.3e-15 56.3 0.3 1.7 1 0 0 1 1 1 1 D-aminoacylase, C-terminal region Amidohydro_5 PF13594.1 EME82228.1 - 5.1e-11 42.2 0.8 1.3e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EME82228.1 - 8.7e-11 42.3 1.0 3.8e-05 23.8 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EME82228.1 - 2e-06 27.6 0.0 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family AP_endonuc_2 PF01261.19 EME82228.1 - 0.061 12.6 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel BTB PF00651.26 EME82229.1 - 7.3e-09 35.6 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SurA_N PF09312.6 EME82230.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 SurA N-terminal domain BID PF06393.6 EME82230.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) GTP_cyclohydroI PF01227.17 EME82231.1 - 4.2e-73 244.4 0.1 5.3e-73 244.1 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EME82231.1 - 0.0019 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Pkinase PF00069.20 EME82233.1 - 1.6e-71 240.4 0.0 2.9e-71 239.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82233.1 - 3.3e-35 121.4 0.0 5.6e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82233.1 - 3.1e-05 23.0 0.1 0.00011 21.3 0.1 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EME82233.1 - 0.0012 17.9 0.3 0.0028 16.7 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME82233.1 - 0.0039 16.9 2.2 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EME82233.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Flavin_Reduct PF01613.13 EME82234.1 - 3.5e-21 75.6 0.0 4.9e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain MARVEL PF01284.18 EME82235.1 - 5.2e-06 26.3 11.9 7.7e-06 25.7 8.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Ctr PF04145.10 EME82235.1 - 0.0082 16.1 3.3 5.9 6.9 0.0 3.4 2 1 0 3 3 3 2 Ctr copper transporter family MFS_1 PF07690.11 EME82236.1 - 1.6e-38 132.3 23.7 2.6e-38 131.6 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3139 PF11337.3 EME82236.1 - 0.11 12.7 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) MFS_1 PF07690.11 EME82238.1 - 3e-15 55.7 23.2 3.1e-09 36.0 10.7 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily DUF4407 PF14362.1 EME82239.1 - 0.12 11.2 12.7 0.15 10.9 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.7 EME82239.1 - 1.9 8.2 6.5 12 5.7 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RRM_1 PF00076.17 EME82241.1 - 0.0052 16.3 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-LYAR PF08790.6 EME82241.1 - 0.13 11.9 0.7 0.33 10.7 0.5 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger HSF_DNA-bind PF00447.12 EME82242.1 - 6.5e-17 61.5 1.2 8.6e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Seryl_tRNA_N PF02403.17 EME82242.1 - 0.0065 16.4 1.4 0.013 15.5 1.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 EME82242.1 - 0.034 12.8 0.7 0.041 12.5 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 EME82242.1 - 0.073 12.8 2.0 0.12 12.1 1.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Exo_endo_phos PF03372.18 EME82244.1 - 6.8e-17 62.2 0.0 1.2e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4232 PF14016.1 EME82244.1 - 0.015 14.9 0.7 0.77 9.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4232) DUF1034 PF06280.7 EME82244.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Fn3-like domain (DUF1034) DCP1 PF06058.8 EME82245.1 - 6.2e-23 81.1 0.2 1e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF3342 PF11822.3 EME82245.1 - 0.057 12.5 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF410 PF04190.8 EME82247.1 - 1.8e-55 188.3 0.0 2.1e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) SNAP PF14938.1 EME82247.1 - 0.16 11.0 0.6 0.91 8.6 0.1 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Transformer PF06495.6 EME82248.1 - 1.5 8.6 32.1 2.5 7.9 22.0 1.5 1 1 0 1 1 1 0 Fruit fly transformer protein DUF1777 PF08648.7 EME82248.1 - 1.5 8.4 27.1 2.7 7.6 18.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) p450 PF00067.17 EME82249.1 - 1.5e-20 73.2 0.0 2e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Init_tRNA_PT PF04179.7 EME82250.1 - 2e-137 458.7 0.0 2.3e-137 458.5 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DivIC PF04977.10 EME82250.1 - 0.068 12.6 0.1 7.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF3656 PF12392.3 EME82250.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Collagenase TPR_11 PF13414.1 EME82251.1 - 4.3e-12 45.4 0.4 3.3e-08 33.0 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EME82251.1 - 5.4e-09 35.2 1.8 0.0023 17.7 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME82251.1 - 1.2e-07 31.0 2.2 0.05 13.2 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME82251.1 - 7.3e-07 28.5 1.3 0.16 11.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME82251.1 - 7.4e-06 25.8 0.2 0.034 14.0 0.0 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME82251.1 - 7.2e-05 23.3 0.1 0.07 13.8 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME82251.1 - 0.0011 18.8 0.0 0.11 12.3 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME82251.1 - 0.0035 17.8 0.3 2 9.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EME82251.1 - 0.0082 16.5 0.2 1.5 9.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME82251.1 - 0.022 15.0 0.6 0.92 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EME82251.1 - 0.054 13.6 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 rve PF00665.21 EME82252.1 - 0.0011 19.0 0.0 0.0012 18.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain LCCL PF03815.14 EME82254.1 - 1.5e-18 66.5 1.6 1.2e-17 63.6 1.1 2.0 1 1 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.16 EME82255.1 - 0.00052 19.0 0.0 0.0019 17.2 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class I and II SGL PF08450.7 EME82256.1 - 0.00067 19.1 0.0 0.2 11.0 0.0 3.3 2 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EME82256.1 - 0.0066 16.3 0.1 9.7 6.6 0.0 3.8 4 0 0 4 4 4 2 Two component regulator propeller Chromadorea_ALT PF05535.7 EME82257.1 - 0.16 12.0 0.4 1.3 9.1 0.1 2.0 2 0 0 2 2 2 0 Chromadorea ALT protein BCS1_N PF08740.6 EME82258.1 - 6.2e-35 120.5 0.1 1.4e-34 119.3 0.0 1.6 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EME82258.1 - 3.1e-08 33.8 0.0 6.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME82258.1 - 0.00074 20.3 0.0 0.0019 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME82258.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME82258.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EME82258.1 - 0.034 14.0 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EME82258.1 - 0.043 12.9 0.0 0.093 11.8 0.0 1.6 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 EME82258.1 - 0.065 12.6 0.2 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.1 EME82258.1 - 0.066 13.1 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EME82258.1 - 0.068 13.4 0.5 0.19 12.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME82258.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UQ_con PF00179.21 EME82260.1 - 1.4e-50 170.3 0.0 1.6e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AroM PF07302.6 EME82262.1 - 0.0017 17.7 0.1 0.0021 17.3 0.1 1.1 1 0 0 1 1 1 1 AroM protein Ribosomal_L19 PF01245.15 EME82263.1 - 5.2e-20 71.3 0.0 7.9e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 ALMS_motif PF15309.1 EME82265.1 - 0.41 10.4 0.1 0.41 10.4 0.1 2.1 3 0 0 3 3 3 0 ALMS motif UAA PF08449.6 EME82266.1 - 3.5e-10 39.2 19.0 4.5e-10 38.9 13.1 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EME82266.1 - 1.2e-08 34.7 7.1 1.2e-08 34.7 4.9 2.8 1 1 2 3 3 3 1 Triose-phosphate Transporter family UPF0370 PF13980.1 EME82266.1 - 0.031 14.0 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Thioredoxin PF00085.15 EME82267.1 - 0.00011 21.7 0.2 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin EF-1_beta_acid PF10587.4 EME82267.1 - 0.052 13.6 0.7 0.052 13.6 0.5 3.7 4 0 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region Spc97_Spc98 PF04130.8 EME82268.1 - 3e-28 98.4 0.1 7.5e-28 97.1 0.0 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family PAD_porph PF04371.10 EME82268.1 - 1.2e-11 44.2 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase GCP5-Mod21 PF14609.1 EME82268.1 - 3.8e-05 22.0 0.0 0.00048 18.3 0.0 2.1 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Drf_FH1 PF06346.7 EME82269.1 - 8.2e-05 22.1 27.7 0.00011 21.7 19.2 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 FAM47 PF14642.1 EME82269.1 - 8.3 5.6 12.1 11 5.2 8.4 1.2 1 0 0 1 1 1 0 FAM47 family Syntaxin-6_N PF09177.6 EME82270.1 - 1.8e-22 79.5 0.5 1.5e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EME82270.1 - 7.1e-11 41.6 1.6 7.1e-11 41.6 1.1 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 EME82270.1 - 0.029 14.4 0.1 0.13 12.2 0.0 2.2 2 1 0 2 2 2 0 Syntaxin-like protein DegS PF05384.6 EME82270.1 - 0.043 13.0 2.1 10 5.2 0.0 3.0 3 0 0 3 3 3 0 Sensor protein DegS TBPIP PF07106.8 EME82270.1 - 0.063 12.8 0.1 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Acyl-CoA_dh_C PF12806.2 EME82270.1 - 0.065 13.0 0.2 6.8 6.5 0.0 2.5 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Baculo_PEP_C PF04513.7 EME82270.1 - 0.12 12.1 0.7 1.3 8.8 0.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EME82270.1 - 0.13 11.9 3.2 5.3 6.7 0.1 2.6 2 1 1 3 3 3 0 Laminin Domain II WXG100 PF06013.7 EME82270.1 - 0.3 11.1 5.4 19 5.3 0.3 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF883 PF05957.8 EME82270.1 - 1.7 9.0 8.3 2.5 8.5 0.3 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.8 EME82270.1 - 3.2 8.1 6.1 4.7 7.6 0.0 3.2 3 1 1 4 4 4 0 Histidine kinase YcaO PF02624.11 EME82271.1 - 0.016 14.6 0.2 0.02 14.3 0.1 1.1 1 0 0 1 1 1 0 YcaO-like family MFS_1 PF07690.11 EME82274.1 - 2.5e-10 39.5 49.8 3.6e-09 35.7 17.3 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.20 EME82275.1 - 7.5e-68 228.4 0.0 1.1e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82275.1 - 5.9e-47 159.9 0.0 8.1e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82275.1 - 0.00011 21.2 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME82275.1 - 0.0057 16.4 0.0 4.1 7.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Abhydrolase_2 PF02230.11 EME82276.1 - 2e-22 79.7 0.0 2.5e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EME82276.1 - 5.6e-08 32.9 0.0 2.9e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME82276.1 - 2.6e-05 24.0 0.0 4.9e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME82276.1 - 0.00017 20.9 0.0 0.00023 20.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EME82276.1 - 0.08 12.4 0.0 0.18 11.3 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold DNA_ligase_IV PF11411.3 EME82276.1 - 0.55 10.0 0.1 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 DNA ligase IV DUF3759 PF12585.3 EME82277.1 - 1.9e-40 136.6 6.3 2.4e-40 136.3 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) PcfK PF14058.1 EME82277.1 - 0.09 12.9 1.1 0.13 12.4 0.8 1.2 1 0 0 1 1 1 0 PcfK-like protein CENP-B_dimeris PF09026.5 EME82278.1 - 0.028 14.6 0.7 0.049 13.8 0.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Herpes_pp85 PF04637.7 EME82278.1 - 0.067 11.4 0.2 0.085 11.1 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LRR_4 PF12799.2 EME82279.1 - 0.13 11.9 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) GATase_4 PF13230.1 EME82280.1 - 4.6e-09 35.3 0.0 1.7e-07 30.2 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EME82280.1 - 7.9e-08 32.3 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EME82280.1 - 0.00019 20.2 0.1 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II NUDIX_2 PF13869.1 EME82281.1 - 7.8e-80 266.6 0.0 1e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EME82281.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Latrotoxin_C PF15658.1 EME82283.1 - 0.69 9.7 5.8 3.9 7.3 4.0 2.0 1 1 0 1 1 1 0 Latrotoxin C-terminal domain NADHdh_A3 PF14987.1 EME82283.1 - 1.9 8.4 6.9 6.6 6.7 0.2 2.6 1 1 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 AMP-binding PF00501.23 EME82284.1 - 4e-46 157.2 0.0 5.6e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EME82286.1 - 0.0083 14.8 14.4 0.0086 14.8 10.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4538 PF15061.1 EME82286.1 - 1.3 8.4 3.3 1 8.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Glycogen_syn PF05693.8 EME82288.1 - 0 1109.3 0.0 0 1109.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EME82288.1 - 3.9e-06 26.3 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME82288.1 - 0.00015 21.9 0.1 0.00038 20.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EME82288.1 - 0.0095 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_hydro_16 PF00722.16 EME82290.1 - 9.4e-13 47.8 1.3 1.2e-12 47.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Grp1_Fun34_YaaH PF01184.14 EME82292.1 - 1.2e-20 73.7 13.2 1.7e-20 73.2 9.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Tetraspannin PF00335.15 EME82292.1 - 0.17 11.1 5.0 0.35 10.1 3.5 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF3270 PF11674.3 EME82292.1 - 0.82 9.7 3.2 1.6 8.7 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Ribosomal_L1 PF00687.16 EME82295.1 - 4.8e-30 104.5 0.0 5.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family p450 PF00067.17 EME82297.1 - 5.7e-56 189.9 0.0 7.1e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FLILHELTA PF10306.4 EME82298.1 - 1.7e-25 88.8 0.0 2.7e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EME82298.1 - 0.0029 17.8 0.5 0.004 17.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Bac_rhamnosid PF05592.6 EME82299.1 - 8.6e-35 119.9 0.7 2.5e-26 92.0 0.5 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EME82299.1 - 9.6e-06 24.5 1.5 1.6e-05 23.8 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 DNA_pol_B_palm PF14792.1 EME82300.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase beta palm ORC6 PF05460.8 EME82301.1 - 0.26 10.3 13.0 0.36 9.8 9.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nucleo_P87 PF07267.6 EME82301.1 - 0.28 9.8 3.8 0.35 9.5 2.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_M22 PF00814.20 EME82303.1 - 4.6e-85 285.3 0.0 5.3e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 EME82303.1 - 0.13 11.3 0.1 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase BAR PF03114.13 EME82304.1 - 1.5e-60 204.5 2.8 1.7e-60 204.4 1.9 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EME82304.1 - 0.013 14.8 5.7 0.05 12.9 3.9 1.9 1 1 0 1 1 1 0 Arfaptin-like domain BAR_2 PF10455.4 EME82304.1 - 0.075 11.9 2.7 0.2 10.5 1.8 1.7 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking T2SF PF00482.18 EME82305.1 - 0.078 12.8 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2015 PF09435.5 EME82307.1 - 1.1e-36 125.3 0.8 4.9e-35 120.1 0.5 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.17 EME82308.1 - 9.3e-32 108.4 0.0 4.6e-15 55.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME82308.1 - 1.7e-17 63.1 0.0 1.8e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME82308.1 - 1.2e-13 50.6 0.0 1.1e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EME82308.1 - 0.056 12.9 0.4 8.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Ribosomal_L28e PF01778.12 EME82309.1 - 2.5e-41 140.7 2.5 3.1e-41 140.4 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Use1 PF09753.4 EME82309.1 - 0.11 11.9 2.0 0.11 11.8 1.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Tom7 PF08038.7 EME82310.1 - 4.1e-18 64.5 0.1 4.8e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 TOM7 family Sec15 PF04091.7 EME82314.1 - 6.3e-100 334.4 1.3 6.3e-100 334.4 0.9 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 EME82314.1 - 4.7e-05 23.2 4.8 4.7e-05 23.2 3.3 2.7 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG7 PF10191.4 EME82314.1 - 0.00013 20.0 5.3 0.0031 15.5 1.9 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) COG5 PF10392.4 EME82314.1 - 0.0003 20.7 5.3 0.0003 20.7 3.6 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec5 PF15469.1 EME82314.1 - 0.0023 17.6 2.0 0.0023 17.6 1.4 3.3 3 1 0 3 3 3 1 Exocyst complex component Sec5 DUF2450 PF10475.4 EME82314.1 - 0.0031 16.4 6.6 0.0074 15.2 4.6 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EME82314.1 - 0.0045 16.6 4.3 0.0045 16.6 3.0 3.4 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF3510 PF12022.3 EME82314.1 - 0.036 14.1 1.8 5 7.2 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Mod_r PF07200.8 EME82314.1 - 0.13 12.1 8.2 0.026 14.4 1.8 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 EME82314.1 - 1.9 8.2 9.3 16 5.2 3.3 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein RRM_2 PF04059.7 EME82315.1 - 6.2e-28 96.6 0.2 1.4e-27 95.5 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 EME82315.1 - 0.0002 20.8 0.4 0.039 13.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME82315.1 - 0.051 13.5 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phosphodiest PF01663.17 EME82316.1 - 1.8e-12 47.3 3.4 4.6e-11 42.6 2.4 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME82316.1 - 3.6e-05 23.1 0.1 7.5e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EME82316.1 - 0.012 14.9 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1583 PF07622.6 EME82319.1 - 0.013 14.0 0.3 0.019 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) WD40 PF00400.27 EME82320.1 - 1.5e-20 72.2 21.2 3.2e-06 26.7 0.9 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Senescence_reg PF04520.8 EME82320.1 - 0.017 15.5 0.6 0.055 13.9 0.4 1.8 1 0 0 1 1 1 0 Senescence regulator MraZ PF02381.13 EME82320.1 - 0.031 14.0 0.0 9.7 6.0 0.0 2.6 2 0 0 2 2 2 0 MraZ protein DUF4611 PF15387.1 EME82320.1 - 5.4 7.2 9.7 1.1 9.4 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) UFD1 PF03152.9 EME82321.1 - 5e-70 234.2 0.0 6.3e-70 233.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EME82321.1 - 0.045 13.3 0.1 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 GPS PF01825.16 EME82324.1 - 0.056 13.5 1.5 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain DUF3321 PF11968.3 EME82326.1 - 6.6e-83 277.6 0.0 8.3e-83 277.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EME82326.1 - 0.00033 20.3 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FANCF PF11107.3 EME82326.1 - 0.0016 17.7 0.7 0.0023 17.2 0.5 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) NAP PF00956.13 EME82327.1 - 7.3e-84 280.7 9.2 7.3e-84 280.7 6.4 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 EME82327.1 - 3.7 7.3 20.1 0.65 9.8 9.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-Tim10_DDP PF02953.10 EME82328.1 - 1.4e-21 75.5 3.8 1.7e-21 75.2 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EME82328.1 - 0.13 11.7 4.0 0.2 11.1 2.8 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Ribosomal_L23 PF00276.15 EME82329.1 - 7.3e-17 61.0 0.5 1.5e-16 60.1 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EME82329.1 - 9.2e-17 60.8 8.7 2.6e-16 59.3 6.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain SRPRB PF09439.5 EME82329.1 - 0.067 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CH PF00307.26 EME82332.1 - 2.2e-40 137.0 0.1 2.3e-19 69.3 0.0 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EME82332.1 - 7.8e-26 89.8 0.3 2.2e-25 88.3 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EME82332.1 - 8.4e-12 44.5 0.5 3.8e-07 29.6 0.0 3.3 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EME82332.1 - 0.0003 20.4 0.3 0.093 12.6 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EME82332.1 - 0.00062 19.3 0.4 0.053 13.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EME82332.1 - 0.0011 18.1 0.1 0.75 9.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EME82332.1 - 0.0038 17.3 0.7 0.019 15.0 0.5 2.3 1 0 0 1 1 1 1 EF-hand domain pair PBD PF00786.23 EME82333.1 - 0.0015 18.9 0.1 0.0061 16.9 0.1 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain DUF3633 PF12315.3 EME82337.1 - 0.1 11.8 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Fcf2 PF08698.6 EME82339.1 - 3e-32 110.5 0.2 3e-32 110.5 0.1 2.6 2 2 0 2 2 2 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.15 EME82340.1 - 9.4e-48 162.2 0.0 1.2e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EME82341.1 - 2e-17 62.7 0.0 3.3e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e TBP-binding PF09247.6 EME82341.1 - 0.025 14.7 0.1 3 8.1 0.1 2.2 2 0 0 2 2 2 0 TATA box-binding protein binding COG2 PF06148.6 EME82342.1 - 8.9e-30 103.2 0.5 8.9e-30 103.2 0.4 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EME82342.1 - 1.9e-06 27.6 0.0 1.9e-06 27.6 0.0 2.3 4 0 0 4 4 4 1 Vps51/Vps67 COG5 PF10392.4 EME82342.1 - 9.4e-05 22.3 0.1 0.00023 21.1 0.0 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Zw10 PF06248.8 EME82342.1 - 0.063 11.4 0.6 0.072 11.2 0.4 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Spc7 PF08317.6 EME82342.1 - 0.12 11.0 2.4 0.081 11.5 0.2 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Fasciclin PF02469.17 EME82344.1 - 2.2e-13 50.3 0.0 4.3e-10 39.6 0.0 2.7 2 2 0 2 2 2 2 Fasciclin domain Methyltransf_23 PF13489.1 EME82346.1 - 6.6e-15 55.2 0.1 9.5e-15 54.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME82346.1 - 1.4e-07 32.0 0.1 1.2e-06 29.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME82346.1 - 1.4e-07 31.1 0.1 1.2e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME82346.1 - 1.8e-07 31.5 0.0 3.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME82346.1 - 0.0014 17.7 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EME82346.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EME82346.1 - 0.0017 18.6 0.0 0.0059 16.9 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME82346.1 - 0.0036 17.7 0.0 0.013 15.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 EME82346.1 - 0.0074 15.3 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.9 EME82346.1 - 0.0088 15.4 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EME82346.1 - 0.013 14.6 0.4 0.029 13.4 0.0 1.7 2 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EME82346.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EME82346.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EME82346.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 EME82347.1 - 5.1e-42 143.9 0.0 8.6e-42 143.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3431 PF11913.3 EME82349.1 - 1.9e-84 282.5 0.0 2.8e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) GPI-anchored PF10342.4 EME82350.1 - 1.3e-17 64.0 0.1 1.9e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UQ_con PF00179.21 EME82351.1 - 1.3e-41 141.3 0.0 2.1e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EME82351.1 - 0.0001 21.7 0.1 0.00021 20.7 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EME82351.1 - 0.00042 20.0 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.24 EME82352.1 - 4.9e-41 140.0 0.0 8.7e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME82352.1 - 4.9e-07 29.9 0.2 0.00017 21.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME82352.1 - 4.2e-06 26.7 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EME82352.1 - 9.2e-06 24.7 0.0 1.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EME82352.1 - 4.1e-05 23.3 0.1 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME82352.1 - 0.00019 21.4 0.1 0.0007 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EME82352.1 - 0.00026 20.0 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EME82352.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME82352.1 - 0.0023 17.9 1.2 0.0041 17.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EME82352.1 - 0.0028 17.3 0.2 0.32 10.6 0.1 2.9 2 1 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EME82352.1 - 0.0034 18.2 0.2 0.0088 16.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME82352.1 - 0.0056 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EME82352.1 - 0.0063 16.2 0.3 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EME82352.1 - 0.0077 16.1 0.1 0.02 14.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EME82352.1 - 0.0079 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EME82352.1 - 0.011 16.0 0.5 0.019 15.2 0.0 1.8 2 1 0 2 2 1 0 AAA domain PhoH PF02562.11 EME82352.1 - 0.012 14.8 1.1 0.19 10.9 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 EME82352.1 - 0.012 14.3 0.1 0.031 12.9 0.0 1.6 1 1 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 EME82352.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EME82352.1 - 0.015 14.3 0.1 0.38 9.8 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_25 PF13481.1 EME82352.1 - 0.017 14.5 1.4 0.25 10.7 0.3 2.4 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EME82352.1 - 0.035 12.9 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EME82352.1 - 0.038 14.1 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EME82352.1 - 0.048 13.2 0.9 0.13 11.8 0.2 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EME82352.1 - 0.048 12.8 0.1 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EME82352.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EME82352.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain zf-CHY PF05495.7 EME82353.1 - 5.2e-13 48.9 19.7 7.5e-13 48.4 13.7 1.2 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_2 PF13240.1 EME82353.1 - 0.12 11.8 0.4 0.12 11.8 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_KTR PF14205.1 EME82353.1 - 0.36 10.3 8.4 1.2 8.6 0.1 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR Zn-ribbon_8 PF09723.5 EME82353.1 - 0.47 10.4 12.6 1.4 8.9 5.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-UDP PF14569.1 EME82353.1 - 0.91 9.3 7.6 0.83 9.4 4.4 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-FPG_IleRS PF06827.9 EME82353.1 - 1.2 8.8 7.0 1.9 8.1 3.6 2.3 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS DRP PF06044.7 EME82353.1 - 1.9 7.4 6.7 1.9 7.3 4.3 1.5 1 1 0 1 1 1 0 Dam-replacing family C1_4 PF07975.7 EME82353.1 - 2.7 8.0 18.9 1.7 8.6 5.4 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain DUF1272 PF06906.6 EME82353.1 - 2.8 7.8 11.7 5.3 6.9 7.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) OSTMP1 PF09777.4 EME82353.1 - 3.3 6.8 13.4 4.8 6.2 9.3 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Exo_endo_phos PF03372.18 EME82354.1 - 9e-23 81.4 0.1 1.6e-22 80.6 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EME82354.1 - 0.026 14.4 0.1 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat Rap1-DNA-bind PF09197.5 EME82354.1 - 0.035 14.6 0.5 0.086 13.4 0.4 1.6 1 0 0 1 1 1 0 Rap1, DNA-binding GFA PF04828.9 EME82355.1 - 2e-10 40.4 1.0 2e-10 40.4 0.7 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PyrI_C PF02748.10 EME82355.1 - 0.032 13.6 0.3 0.1 12.0 0.2 1.8 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-LSD1 PF06943.7 EME82355.1 - 0.36 10.4 0.1 0.36 10.4 0.1 2.5 3 0 0 3 3 3 0 LSD1 zinc finger HDA2-3 PF11496.3 EME82356.1 - 2.6e-21 75.7 0.0 3.4e-20 72.0 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 p450 PF00067.17 EME82358.1 - 4.1e-18 65.1 0.0 9.5e-18 63.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EME82360.1 - 1.6e-102 343.4 25.9 1.8e-102 343.2 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82360.1 - 3.9e-23 81.7 25.4 7.3e-23 80.8 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME82360.1 - 1.6e-07 30.0 1.3 1.6e-07 30.0 0.9 4.0 3 1 1 4 4 4 2 MFS/sugar transport protein PPR_2 PF13041.1 EME82360.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family UNC-93 PF05978.11 EME82360.1 - 1.7 8.1 12.7 0.056 12.9 1.4 2.9 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 HLH PF00010.21 EME82363.1 - 3.7e-11 42.5 0.1 7.1e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CBP PF12192.3 EME82363.1 - 0.047 13.6 0.3 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Fungal calcium binding protein ApoO PF09769.4 EME82363.1 - 0.05 13.3 0.7 0.13 11.9 0.4 1.6 2 0 0 2 2 2 0 Apolipoprotein O DUF3729 PF12526.3 EME82363.1 - 0.15 13.4 5.4 0.22 12.8 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) RESP18 PF14948.1 EME82363.1 - 0.15 12.1 1.0 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 RESP18 domain TB2_DP1_HVA22 PF03134.14 EME82364.1 - 3.7e-31 106.7 6.1 5.2e-31 106.2 4.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.10 EME82365.1 - 9.4e-31 105.8 0.0 2.6e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Fcf1 PF04900.7 EME82365.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Fcf1 Swi5 PF07061.6 EME82366.1 - 3.4e-19 68.4 0.0 3.5e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Swi5 HTH_15 PF12324.3 EME82366.1 - 0.0037 16.8 0.0 0.0039 16.8 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase Ytp1 PF10355.4 EME82367.1 - 1e-84 283.9 11.3 1e-84 283.9 7.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EME82367.1 - 3.3e-33 113.4 0.5 3.3e-33 113.4 0.4 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) zf-DHHC PF01529.15 EME82367.1 - 0.35 10.2 3.3 0.72 9.2 2.2 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase Glyco_transf_8 PF01501.15 EME82368.1 - 1.6e-23 83.3 0.3 2.5e-23 82.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EME82368.1 - 0.0049 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative E1-E2_ATPase PF00122.15 EME82369.1 - 1.2e-63 214.2 1.4 4.1e-62 209.2 0.5 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EME82369.1 - 7e-28 98.5 0.0 2.4e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EME82369.1 - 2e-27 95.9 0.6 2e-27 95.9 0.4 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EME82369.1 - 7.9e-16 57.2 0.0 7.9e-16 57.2 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EME82369.1 - 4.4e-13 49.8 0.0 8.8e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME82369.1 - 3.7e-12 46.0 0.0 7.3e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME82369.1 - 5.1e-07 29.5 1.4 1.4e-05 24.8 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4381 PF14316.1 EME82369.1 - 0.15 12.1 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) UPF0047 PF01894.12 EME82370.1 - 8.7e-41 138.4 0.0 9.9e-41 138.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 F-box PF00646.28 EME82371.1 - 0.0097 15.5 0.0 0.052 13.2 0.0 2.3 2 0 0 2 2 2 1 F-box domain RNA_pol_I_A49 PF06870.7 EME82372.1 - 5.1e-63 212.9 0.1 5.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF2207 PF09972.4 EME82373.1 - 1.3 7.5 3.0 2 6.8 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2404 PF10296.4 EME82374.1 - 1.5e-07 31.4 0.0 3.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ABC1 PF03109.11 EME82375.1 - 1.2e-34 118.8 3.7 3.4e-34 117.3 0.0 2.6 3 0 0 3 3 3 1 ABC1 family Activator-TraM PF11657.3 EME82375.1 - 0.25 10.8 5.5 0.4 10.1 0.3 2.5 2 0 0 2 2 2 0 Transcriptional activator TraM DUF2339 PF10101.4 EME82376.1 - 0.029 12.6 5.4 0.037 12.3 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TAFII28 PF04719.9 EME82378.1 - 0.078 12.7 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 hTAFII28-like protein conserved region DUF605 PF04652.11 EME82378.1 - 0.59 9.4 11.7 0.66 9.3 8.1 1.1 1 0 0 1 1 1 0 Vta1 like EHN PF06441.7 EME82379.1 - 3.8e-30 104.0 0.0 5.6e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Acyl_transf_3 PF01757.17 EME82381.1 - 4.9e-27 94.6 47.5 8.6e-27 93.8 32.9 1.4 1 1 0 1 1 1 1 Acyltransferase family P5CR_dimer PF14748.1 EME82382.1 - 1.1e-38 131.5 1.2 1.1e-38 131.5 0.8 2.3 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EME82382.1 - 4.1e-19 68.7 1.0 9.8e-19 67.5 0.7 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EME82382.1 - 3.1e-05 23.7 4.2 0.00033 20.4 2.0 2.5 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EME82382.1 - 0.00022 21.1 0.3 0.00044 20.1 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EME82382.1 - 0.002 18.3 0.1 0.0042 17.3 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding PDH PF02153.12 EME82382.1 - 0.0035 16.2 0.2 0.0079 15.1 0.1 1.6 1 1 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.15 EME82382.1 - 0.0079 16.2 0.9 0.019 15.0 0.3 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.10 EME82382.1 - 0.086 12.9 0.1 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Umbravirus_LDM PF04817.7 EME82383.1 - 0.036 13.2 5.7 0.043 12.9 3.9 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family SRP-alpha_N PF04086.8 EME82383.1 - 0.16 11.3 6.0 0.19 11.0 4.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Dmrt1 PF12374.3 EME82383.1 - 0.35 11.2 14.1 0.055 13.8 7.0 1.7 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Lamp PF01299.12 EME82383.1 - 0.66 9.0 8.4 0.79 8.8 5.8 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) OCC1 PF15506.1 EME82383.1 - 1.5 8.7 0.0 1.5 8.7 0.0 2.5 3 0 0 3 3 3 0 OCC1 family Presenilin PF01080.12 EME82383.1 - 2.3 6.9 6.6 2.5 6.8 4.5 1.0 1 0 0 1 1 1 0 Presenilin MAP65_ASE1 PF03999.7 EME82383.1 - 5.9 5.3 8.0 6.5 5.2 5.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GCN5L1 PF06320.8 EME82385.1 - 0.089 12.6 7.1 0.19 11.5 4.9 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Peptidase_M24 PF00557.19 EME82386.1 - 3.4e-41 141.0 0.0 5.5e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EME82386.1 - 1.5e-26 93.4 0.1 3.2e-21 76.2 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ArgJ PF01960.13 EME82387.1 - 2.1e-128 428.0 5.7 7.3e-127 422.9 3.9 2.1 1 1 0 1 1 1 1 ArgJ family Cyclin_N PF00134.18 EME82388.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PurA PF04845.8 EME82388.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein RRS1 PF04939.7 EME82388.1 - 0.033 13.6 0.1 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Abhydrolase_6 PF12697.2 EME82389.1 - 1.5e-16 60.9 0.1 1.7e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME82389.1 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 EME82390.1 - 3.8e-08 32.5 0.0 6.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_32 PF13679.1 EME82391.1 - 3.8e-22 78.5 0.0 6.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME82391.1 - 0.023 15.2 0.0 0.074 13.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Glyco_transf_15 PF01793.11 EME82392.1 - 5.1e-136 452.9 9.7 6.3e-136 452.6 6.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_67N PF03648.9 EME82394.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus F-box-like_2 PF13013.1 EME82395.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.4 1 1 0 1 1 1 0 F-box-like domain MRP-S33 PF08293.6 EME82396.1 - 3.4e-25 87.8 0.1 3.8e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.21 EME82397.1 - 1.5e-22 80.2 0.1 1.9e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EME82397.1 - 2.2e-16 59.9 0.2 2.5e-16 59.7 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease-III-like Glyco_hydro_18 PF00704.23 EME82398.1 - 5.4e-93 312.1 4.8 6.3e-93 311.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cpn60_TCP1 PF00118.19 EME82399.1 - 2e-115 386.2 9.9 2.3e-115 386.0 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family POR PF01558.13 EME82399.1 - 0.046 13.6 2.5 4 7.3 0.0 3.0 3 0 0 3 3 3 0 Pyruvate ferredoxin/flavodoxin oxidoreductase cobW PF02492.14 EME82404.1 - 4.9e-48 162.9 4.6 6e-36 123.5 0.2 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EME82404.1 - 1.9e-17 62.7 0.1 4.6e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 EME82404.1 - 4.2e-06 25.7 0.2 0.0016 17.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EME82404.1 - 0.00069 19.3 0.8 0.0011 18.6 0.0 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EME82404.1 - 0.0073 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase CbiA PF01656.18 EME82404.1 - 0.0096 15.3 0.1 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EME82404.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME82404.1 - 0.038 14.1 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EME82404.1 - 0.039 13.5 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EME82404.1 - 0.04 14.2 2.4 0.23 11.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain GTP_EFTU PF00009.22 EME82404.1 - 0.043 13.2 0.3 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EME82404.1 - 0.047 13.1 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain ATP_bind_1 PF03029.12 EME82404.1 - 0.055 12.9 0.1 10 5.6 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EME82404.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EME82404.1 - 0.062 13.2 0.7 0.29 11.1 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EME82404.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain UPF0004 PF00919.15 EME82404.1 - 0.13 12.1 0.7 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 RXT2_N PF08595.6 EME82404.1 - 4.7 6.9 9.7 0.082 12.7 1.6 1.8 2 0 0 2 2 1 0 RXT2-like, N-terminal DUF1993 PF09351.5 EME82405.1 - 2.7e-47 160.7 0.2 3e-47 160.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF348 PF03990.9 EME82405.1 - 0.025 14.1 0.1 5.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF348) Sec15 PF04091.7 EME82405.1 - 0.061 12.6 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Thioredoxin PF00085.15 EME82407.1 - 2.6e-05 23.8 0.0 4.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EME82407.1 - 0.01 15.9 0.0 0.1 12.8 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin-like domain HyaE PF07449.6 EME82407.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glyco_hydro_3 PF00933.16 EME82408.1 - 1.7e-81 273.4 0.0 2.4e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME82408.1 - 3.2e-30 105.3 0.0 1.6e-18 67.0 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME82408.1 - 1.8e-19 69.4 0.1 3.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SET PF00856.23 EME82409.1 - 7.7e-14 52.3 0.0 2.1e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 SET domain EPL1 PF10513.4 EME82410.1 - 2.9e-27 95.8 0.3 2.9e-27 95.8 0.2 2.3 2 1 0 2 2 2 1 Enhancer of polycomb-like TPR_MLP1_2 PF07926.7 EME82410.1 - 3.5 7.3 8.5 14 5.4 1.4 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SPC22 PF04573.7 EME82411.1 - 3.2e-37 127.4 0.0 4.1e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Clr5 PF14420.1 EME82414.1 - 1.9e-06 27.6 0.9 3.9e-06 26.6 0.6 1.6 1 0 0 1 1 1 1 Clr5 domain Dynein_light PF01221.13 EME82414.1 - 0.063 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Dynein light chain type 1 Fork_head PF00250.13 EME82415.1 - 4.9e-33 113.0 0.1 1.3e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 Fork head domain Dscam_C PF12355.3 EME82416.1 - 0.027 14.7 0.7 0.049 13.8 0.5 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Mito_fiss_reg PF05308.6 EME82416.1 - 2.2 7.5 8.2 4.1 6.6 4.1 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator Sec1 PF00995.18 EME82418.1 - 2.1e-148 495.4 0.0 2.5e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ACBP PF00887.14 EME82418.1 - 0.07 12.7 0.0 0.24 11.0 0.0 1.9 1 0 0 1 1 1 0 Acyl CoA binding protein UQ_con PF00179.21 EME82419.1 - 1e-38 131.9 0.0 1.3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME82419.1 - 0.026 14.3 0.4 0.061 13.2 0.3 1.6 1 1 1 2 2 2 0 RWD domain UBA_4 PF14555.1 EME82420.1 - 1.3e-06 27.8 0.0 3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 EME82420.1 - 0.00076 18.8 3.5 0.002 17.5 2.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif UBA PF00627.26 EME82420.1 - 0.097 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain ASD2 PF08687.6 EME82420.1 - 0.1 11.8 5.0 0.76 9.0 2.3 2.5 2 1 1 3 3 3 0 Apx/Shroom domain ASD2 CDP-OH_P_transf PF01066.16 EME82422.1 - 1.7e-16 60.3 7.3 1.7e-16 60.3 5.0 2.2 2 2 1 3 3 3 1 CDP-alcohol phosphatidyltransferase Gti1_Pac2 PF09729.4 EME82424.1 - 8.7e-60 201.3 0.0 1.1e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family DUF4131 PF13567.1 EME82425.1 - 0.96 8.8 5.2 1.3 8.4 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MIF4G_like PF09088.6 EME82426.1 - 9.7e-79 263.2 0.8 1.7e-78 262.4 0.6 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EME82426.1 - 7e-49 166.3 0.1 1.1e-48 165.7 0.1 1.2 1 0 0 1 1 1 1 MIF4G like G10 PF01125.12 EME82427.1 - 6.3e-66 220.3 7.5 7.1e-66 220.2 5.2 1.0 1 0 0 1 1 1 1 G10 protein Tau95 PF09734.4 EME82427.1 - 0.075 12.3 0.3 0.084 12.1 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Sad1_UNC PF07738.8 EME82428.1 - 6.4e-34 116.6 0.4 1.1e-33 115.8 0.3 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal GIDA PF01134.17 EME82429.1 - 1.4e-155 518.0 0.0 1.7e-155 517.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EME82429.1 - 5.1e-18 64.9 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EME82429.1 - 1.1e-07 31.9 0.4 3.6e-07 30.2 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME82429.1 - 1.8e-07 30.6 0.7 3.1e-07 29.8 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EME82429.1 - 1.3e-05 24.2 1.4 0.059 12.2 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME82429.1 - 3.3e-05 22.9 1.7 4.4e-05 22.5 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EME82429.1 - 0.00018 21.8 0.2 0.00045 20.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EME82429.1 - 0.0024 17.4 0.1 0.0045 16.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EME82429.1 - 0.014 13.9 1.0 0.079 11.4 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EME82429.1 - 0.15 10.6 0.4 12 4.3 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EME82429.1 - 0.15 12.3 0.2 0.47 10.7 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Tropomodulin PF03250.9 EME82430.1 - 0.027 13.9 1.7 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 Tropomodulin DUF3418 PF11898.3 EME82430.1 - 0.039 12.3 0.1 0.056 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Metallophos PF00149.23 EME82431.1 - 1.6e-41 141.9 0.5 2.6e-41 141.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_61 PF03443.9 EME82432.1 - 0.089 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.3 EME82433.1 - 6.8e-18 64.6 1.4 2.3e-17 62.9 0.9 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) DUF3481 PF11980.3 EME82433.1 - 2.1 8.2 6.6 7.1 6.5 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) DUF1546 PF07571.8 EME82434.1 - 5.9e-32 109.6 0.0 1.3e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EME82434.1 - 3.4e-26 90.9 0.2 7.1e-26 89.9 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EME82434.1 - 8.9e-08 32.1 0.1 7.5e-07 29.1 0.3 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EME82434.1 - 0.0001 22.2 0.4 0.00037 20.5 0.2 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EME82434.1 - 0.0047 16.6 0.1 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 EME82434.1 - 0.035 14.2 0.1 0.093 12.9 0.1 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EME82434.1 - 0.037 13.8 0.3 0.13 12.0 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit F-box PF00646.28 EME82436.1 - 0.014 15.0 0.1 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EME82436.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like Sfi1 PF08457.5 EME82436.1 - 0.13 10.6 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein DEC-1_N PF04625.8 EME82436.1 - 0.53 8.9 4.2 0.77 8.3 2.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TPR_11 PF13414.1 EME82438.1 - 7.1e-09 35.1 0.2 5.7e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 EME82438.1 - 3.1e-07 30.0 0.0 1.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain TPR_2 PF07719.12 EME82438.1 - 0.00024 20.7 1.8 2.6 8.1 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DnaJ PF00226.26 EME82438.1 - 0.0039 16.9 0.1 0.012 15.3 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EME82438.1 - 0.089 12.7 0.4 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MIP-T3 PF10243.4 EME82438.1 - 7.9 4.8 25.4 0.6 8.5 13.6 1.9 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 tRNA-synt_2b PF00587.20 EME82439.1 - 3.6e-36 124.3 0.1 6.7e-36 123.4 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EME82439.1 - 1.2e-14 54.2 7.5 1.2e-14 54.2 5.2 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_His PF13393.1 EME82439.1 - 0.02 13.9 0.9 0.23 10.4 0.0 2.3 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Tho2 PF11262.3 EME82439.1 - 0.2 10.6 2.7 0.36 9.8 1.8 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Bap31 PF05529.7 EME82439.1 - 1.2 8.5 6.5 2.6 7.4 4.5 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Mur_ligase_M PF08245.7 EME82440.1 - 2.1e-07 31.2 0.0 6.1e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain LigB PF02900.13 EME82440.1 - 0.011 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_S29 PF02907.10 EME82440.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Striatin PF08232.7 EME82441.1 - 6.8e-34 117.0 5.2 6.8e-34 117.0 3.6 2.4 3 0 0 3 3 3 1 Striatin family WD40 PF00400.27 EME82441.1 - 3.5e-32 109.1 17.1 1.9e-09 37.0 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EME82441.1 - 0.073 12.7 0.9 6.6 6.4 0.0 2.8 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term DivIC PF04977.10 EME82441.1 - 7.9 6.0 7.8 4.3 6.9 3.2 2.1 2 0 0 2 2 2 0 Septum formation initiator Bunya_RdRp PF04196.7 EME82443.1 - 0.069 11.1 0.0 0.069 11.1 0.0 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase STE PF02200.11 EME82444.1 - 1.8e-58 195.4 0.2 3.4e-58 194.5 0.1 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EME82444.1 - 8.4e-10 38.4 10.9 0.00012 22.1 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME82444.1 - 1.7e-08 34.2 9.8 0.00079 19.5 1.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME82444.1 - 7e-08 32.3 3.1 7e-08 32.3 2.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EME82444.1 - 0.00074 19.3 0.2 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME82444.1 - 0.0089 16.1 0.8 0.28 11.3 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME82444.1 - 0.057 13.6 2.0 0.58 10.4 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MFS_1 PF07690.11 EME82449.1 - 2.1e-25 89.2 31.3 2.6e-25 88.8 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EME82449.1 - 0.0087 16.4 0.1 0.022 15.1 0.1 1.8 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4564 PF15169.1 EME82449.1 - 0.084 12.5 0.3 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) DUF1228 PF06779.9 EME82449.1 - 2.7 8.0 11.3 1.6 8.8 0.4 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF1228) HdeA PF06411.6 EME82454.1 - 0.0024 17.7 10.5 0.012 15.6 0.7 3.1 3 0 0 3 3 3 1 HdeA/HdeB family Herpes_BLLF1 PF05109.8 EME82454.1 - 0.53 8.1 32.6 0.64 7.9 22.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TFIIA PF03153.8 EME82454.1 - 0.87 9.4 6.3 1 9.1 4.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL32 PF06070.6 EME82454.1 - 3.6 5.9 10.4 4.5 5.5 7.2 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HET PF06985.6 EME82456.1 - 5e-25 88.2 0.0 5.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CoA_binding PF02629.14 EME82457.1 - 2.7e-27 95.1 3.5 1.7e-26 92.5 0.5 2.4 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EME82457.1 - 9.3e-25 87.0 0.6 1.5e-24 86.3 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EME82457.1 - 6.3e-06 25.8 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EME82457.1 - 0.0016 18.5 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain IlvN PF07991.7 EME82457.1 - 0.017 14.4 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Radical_SAM PF04055.16 EME82458.1 - 2.5e-14 53.7 0.0 5.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EME82458.1 - 4.2e-11 42.7 0.1 1.2e-10 41.2 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME82458.1 - 0.11 12.6 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PDT PF00800.13 EME82459.1 - 1.3e-62 210.5 0.0 3e-62 209.3 0.0 1.7 1 0 0 1 1 1 1 Prephenate dehydratase eRF1_2 PF03464.10 EME82460.1 - 4e-47 159.8 0.1 7.1e-47 159.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EME82460.1 - 1.4e-39 134.8 0.3 3.5e-39 133.5 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EME82460.1 - 1.8e-28 98.7 0.0 3.2e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Aa_trans PF01490.13 EME82461.1 - 3.9e-67 226.5 20.4 4.7e-67 226.2 14.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EME82461.1 - 0.0022 16.8 8.5 0.0022 16.8 5.9 2.3 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family MaoC_dehydratas PF01575.14 EME82462.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain CorA PF01544.13 EME82463.1 - 4.2e-44 150.7 0.0 5.5e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 EME82464.1 - 1.7e-23 82.2 0.3 2e-23 81.9 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) 7TMR-DISM_7TM PF07695.6 EME82464.1 - 0.011 15.4 0.1 0.013 15.2 0.1 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling MFS_1 PF07690.11 EME82464.1 - 0.013 14.2 0.1 0.014 14.1 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily zf-rbx1 PF12678.2 EME82465.1 - 1.3e-35 121.3 13.5 1.6e-35 121.0 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME82465.1 - 2.6e-17 62.4 10.1 3.4e-17 62.0 7.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EME82465.1 - 1.9e-07 30.8 12.0 1e-06 28.4 8.3 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME82465.1 - 0.0012 18.4 11.6 0.017 14.7 8.1 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME82465.1 - 0.0023 17.9 3.6 0.0023 17.9 2.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME82465.1 - 0.0034 17.0 9.8 0.32 10.7 6.9 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EME82465.1 - 0.52 10.3 9.6 2.6 8.0 6.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EME82465.1 - 0.64 9.7 6.8 17 5.2 4.7 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EME82465.1 - 0.71 9.6 11.8 6 6.6 8.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EME82465.1 - 1.7 8.8 10.5 1.1e+02 3.0 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain 2-Hacid_dh_C PF02826.14 EME82466.1 - 3.6e-48 163.0 0.0 6.9e-48 162.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME82466.1 - 1.5e-34 118.3 0.0 1.9e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME82466.1 - 0.00019 21.3 0.8 0.001 18.9 0.1 2.4 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EME82466.1 - 0.00033 20.0 0.0 0.0007 19.0 0.0 1.6 1 0 0 1 1 1 1 ACT domain 3HCDH_N PF02737.13 EME82466.1 - 0.18 11.4 1.0 3.8 7.1 0.3 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AstE_AspA PF04952.9 EME82468.1 - 3.6e-31 108.1 0.0 4.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Sugar_tr PF00083.19 EME82469.1 - 3.7e-117 391.6 25.4 4.4e-117 391.4 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82469.1 - 2e-25 89.2 32.8 5.3e-23 81.2 13.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 EME82469.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) 7TM-7TMR_HD PF07698.6 EME82469.1 - 1.4 8.2 18.7 0.041 13.3 3.6 3.6 2 1 1 3 3 3 0 7TM receptor with intracellular HD hydrolase FAM217 PF15344.1 EME82470.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 FAM217 family His_biosynth PF00977.16 EME82471.1 - 5.8e-30 104.2 0.0 7.3e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EME82471.1 - 0.03 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EME82472.1 - 0.00037 20.5 10.1 0.00037 20.5 7.0 2.5 2 2 0 2 2 2 1 Domain of unknown function (DUF4602) HET PF06985.6 EME82475.1 - 3.4e-19 69.3 0.1 5.6e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_1c PF00749.16 EME82476.1 - 6.2e-107 356.8 0.3 8.9e-107 356.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EME82476.1 - 1.2e-34 119.4 2.8 1.2e-34 119.4 1.9 1.9 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EME82476.1 - 3.3e-05 24.2 0.8 0.00012 22.4 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EME82476.1 - 0.013 14.6 1.6 0.05 12.7 1.1 2.0 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain F-box-like_2 PF13013.1 EME82477.1 - 0.037 13.7 0.0 0.58 9.9 0.0 2.5 1 1 0 1 1 1 0 F-box-like domain Rax2 PF12768.2 EME82478.1 - 0.082 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1183 PF06682.7 EME82478.1 - 1.8 8.0 8.4 14 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Glyco_hydro_47 PF01532.15 EME82479.1 - 2.6e-164 547.1 0.0 3e-164 546.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EME82479.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) DUF89 PF01937.14 EME82480.1 - 4.2e-128 427.1 0.1 4.8e-128 426.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 adh_short PF00106.20 EME82481.1 - 6.8e-14 52.1 0.0 8.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME82481.1 - 1.3e-08 34.6 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME82481.1 - 2.3e-07 30.8 0.0 3.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peripla_BP_5 PF13433.1 EME82481.1 - 0.04 12.6 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain MIS13 PF08202.6 EME82482.1 - 0.0015 17.6 0.3 0.0024 16.9 0.2 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family HSBP1 PF06825.7 EME82482.1 - 0.024 14.1 0.2 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 IncA PF04156.9 EME82482.1 - 0.046 13.3 2.5 0.099 12.2 1.8 1.6 1 1 0 1 1 1 0 IncA protein BBP1_C PF15272.1 EME82482.1 - 0.058 12.9 0.3 0.43 10.1 0.2 2.1 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal OmpH PF03938.9 EME82482.1 - 0.1 12.5 0.4 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 EME82485.1 - 7.9e-69 231.6 0.6 1.9e-68 230.4 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82485.1 - 1.1e-53 182.0 0.1 2.1e-53 181.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EME82485.1 - 6.1e-20 71.4 0.0 2.2e-19 69.6 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EME82485.1 - 6.2e-06 25.3 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EME82485.1 - 0.00014 22.0 1.5 0.00014 22.0 1.1 1.9 2 0 0 2 2 2 1 PH domain APH PF01636.18 EME82485.1 - 0.057 13.1 3.3 0.072 12.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF1996 PF09362.5 EME82486.1 - 1e-62 211.8 0.3 1.8e-62 211.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EME82486.1 - 1.4e-36 124.3 34.4 1.3e-14 53.8 8.9 4.0 4 0 0 4 4 4 3 WSC domain DUF3415 PF11895.3 EME82486.1 - 0.11 12.3 1.2 0.24 11.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) CMAS PF02353.15 EME82487.1 - 9.9e-37 126.4 0.5 1.4e-36 125.9 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EME82487.1 - 3.3e-17 62.4 0.0 4.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME82487.1 - 6e-15 55.3 0.0 9.3e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME82487.1 - 1.3e-12 48.0 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME82487.1 - 1.6e-12 47.9 0.0 3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME82487.1 - 4.3e-10 39.9 0.0 8.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME82487.1 - 5.6e-07 29.1 0.0 1.4e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EME82487.1 - 2.8e-05 24.4 0.0 5.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME82487.1 - 0.00093 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EME82487.1 - 0.0013 17.9 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.7 EME82487.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.14 EME82487.1 - 0.0018 17.8 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MyTH4 PF00784.12 EME82487.1 - 0.0018 18.1 0.0 0.0059 16.5 0.0 1.8 1 0 0 1 1 1 1 MyTH4 domain Methyltransf_26 PF13659.1 EME82487.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EME82487.1 - 0.0082 15.6 0.0 0.019 14.4 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 EME82487.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Nol1_Nop2_Fmu PF01189.12 EME82487.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 NOL1/NOP2/sun family tRNA_U5-meth_tr PF05958.6 EME82487.1 - 0.035 12.7 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FTO_CTD PF12934.2 EME82487.1 - 0.05 13.1 1.7 0.11 12.1 1.1 1.5 1 0 0 1 1 1 0 FTO C-terminal domain GidB PF02527.10 EME82487.1 - 0.085 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.1 EME82487.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AT_hook PF02178.14 EME82488.1 - 0.056 13.1 3.3 0.056 13.1 2.3 2.6 2 0 0 2 2 2 0 AT hook motif Pox_Ag35 PF03286.9 EME82488.1 - 2.5 7.5 10.4 3 7.3 7.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CoaE PF01121.15 EME82489.1 - 9.1e-43 145.7 0.0 6.1e-42 143.0 0.0 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 EME82489.1 - 0.00083 19.2 0.0 0.012 15.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME82489.1 - 0.0015 19.3 1.4 0.0082 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME82489.1 - 0.085 13.1 0.6 0.29 11.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain Gcd10p PF04189.8 EME82492.1 - 8.6e-69 231.9 0.0 1.1e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family DUF1726 PF08351.6 EME82492.1 - 0.038 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) DUF3328 PF11807.3 EME82493.1 - 1.1e-38 133.1 3.2 1.4e-38 132.8 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CD52 PF15116.1 EME82493.1 - 0.061 13.1 0.1 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 CAMPATH-1 antigen DUF4479 PF14794.1 EME82493.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Ribonuclease_T2 PF00445.13 EME82494.1 - 3.2e-31 108.4 0.2 5.1e-31 107.7 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family HATPase_c PF02518.21 EME82497.1 - 9.2e-22 76.8 0.0 2e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME82497.1 - 1.7e-17 63.4 0.0 5.5e-17 61.7 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EME82497.1 - 1.5e-13 50.5 0.0 5.6e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PhyH PF05721.8 EME82498.1 - 8e-22 78.3 0.1 1e-21 77.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cellulase PF00150.13 EME82499.1 - 7.2e-11 41.8 7.8 3e-10 39.7 5.4 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lyase_catalyt PF09093.6 EME82499.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic Complex1_LYR PF05347.10 EME82499.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF4227 PF14004.1 EME82500.1 - 0.021 14.6 0.0 3.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) TPR_11 PF13414.1 EME82502.1 - 0.043 13.4 1.1 0.073 12.7 0.1 1.9 2 0 0 2 2 2 0 TPR repeat CFEM PF05730.6 EME82506.1 - 4.8e-14 51.9 13.2 8e-14 51.2 9.2 1.4 1 0 0 1 1 1 1 CFEM domain Pectinesterase PF01095.14 EME82506.1 - 0.026 13.0 0.1 0.045 12.3 0.1 1.3 1 0 0 1 1 1 0 Pectinesterase EI24 PF07264.6 EME82506.1 - 0.39 10.1 11.3 0.36 10.2 2.4 2.3 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) IBR PF01485.16 EME82507.1 - 1.9e-05 24.4 14.7 0.0058 16.4 1.2 2.6 2 0 0 2 2 2 2 IBR domain zf-AN1 PF01428.11 EME82507.1 - 0.36 10.7 13.7 2.6 7.9 1.4 2.8 2 0 0 2 2 2 0 AN1-like Zinc finger PALP PF00291.20 EME82510.1 - 4.9e-59 200.0 0.2 5.7e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 EME82511.1 - 9.7e-84 280.8 2.8 2.7e-83 279.3 0.4 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EME82511.1 - 4e-08 32.6 4.3 0.051 13.6 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EME82511.1 - 7.7e-08 32.5 4.8 7.7e-05 22.9 0.3 6.0 3 2 3 6 6 6 2 HEAT repeats DUF1546 PF07571.8 EME82511.1 - 0.058 13.5 0.4 0.55 10.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EME82511.1 - 0.061 13.8 0.4 0.061 13.8 0.3 7.3 5 2 5 10 10 10 0 HEAT-like repeat AMP-binding PF00501.23 EME82516.1 - 4.2e-16 58.3 0.2 6.7e-16 57.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.6 EME82517.1 - 8.4e-24 84.0 0.1 2.9e-22 79.0 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore complex component DUF3328 PF11807.3 EME82521.1 - 3.2e-34 118.5 9.0 4.7e-34 117.9 6.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.13 EME82523.1 - 6.5e-19 67.8 0.3 1.3e-18 66.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 EME82524.1 - 5.5e-39 133.7 0.0 6.9e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 EME82525.1 - 2.2e-61 207.3 0.0 4.9e-61 206.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82525.1 - 4.2e-37 127.6 0.0 6.5e-35 120.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME82525.1 - 3e-10 39.5 0.0 3.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME82525.1 - 0.0035 17.1 0.0 0.0097 15.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family STE3 PF02076.10 EME82526.1 - 2.2e-67 227.1 18.9 2.9e-67 226.7 13.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor BAR PF03114.13 EME82527.1 - 3.9e-44 150.8 11.6 4.7e-44 150.6 8.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EME82527.1 - 0.002 17.0 3.8 0.0027 16.6 2.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Pkinase PF00069.20 EME82528.1 - 3.4e-66 223.0 0.0 4.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82528.1 - 2.1e-31 108.9 0.0 2.9e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82528.1 - 0.0047 15.9 0.0 0.048 12.6 0.0 2.1 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EME82528.1 - 0.26 10.6 0.3 0.53 9.6 0.2 1.4 1 1 0 1 1 1 0 RIO1 family ABC_tran PF00005.22 EME82529.1 - 4.7e-54 182.4 0.1 2.1e-31 109.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EME82529.1 - 1.4e-51 175.5 21.5 1.3e-27 96.9 2.2 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EME82529.1 - 7.1e-10 39.3 0.0 0.015 15.2 0.0 4.5 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EME82529.1 - 2.8e-07 30.0 3.2 0.061 12.5 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME82529.1 - 3.7e-07 30.6 0.1 0.00019 21.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME82529.1 - 5.8e-06 25.8 0.0 0.14 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EME82529.1 - 6.3e-05 22.8 0.1 0.046 13.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EME82529.1 - 9.5e-05 22.4 0.1 0.72 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EME82529.1 - 0.00012 22.2 1.3 1.3 9.1 0.1 4.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EME82529.1 - 0.00016 21.1 0.6 0.37 10.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EME82529.1 - 0.00017 21.4 0.1 0.22 11.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EME82529.1 - 0.00023 20.7 0.8 0.34 10.3 0.0 2.6 3 0 0 3 3 2 2 AAA-like domain DUF258 PF03193.11 EME82529.1 - 0.00023 20.3 0.1 0.2 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EME82529.1 - 0.00029 21.3 0.4 0.74 10.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EME82529.1 - 0.00031 21.5 0.0 1.3 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME82529.1 - 0.00041 19.3 0.0 0.041 12.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EME82529.1 - 0.00079 19.1 0.2 3 7.5 0.0 3.2 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EME82529.1 - 0.0017 18.2 3.0 0.12 12.1 0.0 2.9 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.7 EME82529.1 - 0.0024 16.9 0.4 2.2 7.3 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.24 EME82529.1 - 0.0079 16.4 0.2 4.2 7.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EME82529.1 - 0.0095 15.6 0.0 0.054 13.1 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EME82529.1 - 0.0098 16.1 0.1 8.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EME82529.1 - 0.013 14.8 0.2 6.7 6.0 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 EME82529.1 - 0.017 14.9 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EME82529.1 - 0.021 14.3 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EME82529.1 - 0.036 13.8 0.4 2.2 8.0 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EME82529.1 - 0.072 12.8 0.5 13 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EME82529.1 - 0.077 12.5 0.4 15 5.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EME82529.1 - 0.08 13.1 0.2 26 5.0 0.0 3.1 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.4 EME82529.1 - 0.087 11.4 0.9 4.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 EME82529.1 - 0.099 12.2 0.4 5.2 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EME82529.1 - 0.13 11.8 1.7 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain CbiA PF01656.18 EME82529.1 - 0.15 11.4 0.7 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 EME82529.1 - 0.37 9.7 1.0 10 4.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.1 EME82529.1 - 0.51 9.3 0.0 1.1 8.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EME82529.1 - 0.91 8.9 2.9 2.6 7.4 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EME82530.1 - 3.8e-47 160.0 0.1 9.7e-23 80.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EME82530.1 - 5e-22 77.5 6.1 5e-22 77.5 4.3 2.4 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EME82530.1 - 7e-19 68.8 0.3 0.00077 19.5 0.1 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EME82530.1 - 1.8e-09 37.1 0.5 0.35 10.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME82530.1 - 3.8e-09 37.1 4.3 0.042 14.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EME82530.1 - 1.5e-08 34.0 0.3 0.00067 19.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EME82530.1 - 4.5e-07 29.2 0.1 0.00023 20.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME82530.1 - 7.7e-07 29.9 0.1 0.0097 16.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EME82530.1 - 1e-06 29.0 1.6 0.035 14.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 EME82530.1 - 2.5e-06 27.6 0.0 0.067 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EME82530.1 - 3.3e-06 27.6 0.0 0.012 16.0 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_15 PF13175.1 EME82530.1 - 7.4e-05 21.9 2.9 0.05 12.6 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 EME82530.1 - 7.8e-05 22.8 0.0 0.66 10.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EME82530.1 - 0.00011 21.9 0.1 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EME82530.1 - 0.00012 22.0 0.0 0.83 9.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EME82530.1 - 0.00019 21.5 1.2 0.79 9.9 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_16 PF13191.1 EME82530.1 - 0.00019 21.4 0.3 0.29 11.0 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EME82530.1 - 0.00038 20.3 0.2 0.38 10.7 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EME82530.1 - 0.00039 20.1 0.8 0.82 9.3 0.0 3.2 3 1 0 3 3 3 2 Archaeal ATPase AAA_28 PF13521.1 EME82530.1 - 0.0005 20.0 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME82530.1 - 0.00051 19.9 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME82530.1 - 0.00061 19.5 0.1 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EME82530.1 - 0.0021 17.4 0.0 1.4 8.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 EME82530.1 - 0.0031 16.3 0.1 0.9 8.3 0.0 3.3 2 1 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.18 EME82530.1 - 0.0039 17.0 0.8 2.1 8.1 0.0 3.6 2 1 1 3 3 3 1 Dynamin family SbcCD_C PF13558.1 EME82530.1 - 0.0052 16.6 0.5 0.67 9.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EME82530.1 - 0.0054 16.2 0.0 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EME82530.1 - 0.0061 16.2 0.7 0.23 11.1 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EME82530.1 - 0.0099 14.3 0.6 11 4.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EME82530.1 - 0.011 15.1 0.4 4.9 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain Ras PF00071.17 EME82530.1 - 0.013 14.8 0.2 6.7 6.0 0.0 2.7 3 0 0 3 3 3 0 Ras family VirE PF05272.6 EME82530.1 - 0.018 14.4 0.1 4.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.4 EME82530.1 - 0.047 12.6 0.1 7 5.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 EME82530.1 - 0.13 11.9 0.4 13 5.4 0.1 2.6 2 0 0 2 2 2 0 NTPase ABC_membrane PF00664.18 EME82531.1 - 7.4e-75 251.8 33.4 1.4e-45 155.8 3.7 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME82531.1 - 2.4e-51 173.6 0.0 1.5e-30 106.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME82531.1 - 3.4e-10 39.5 4.9 0.0016 17.6 0.1 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME82531.1 - 3.6e-06 27.0 3.2 0.021 14.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EME82531.1 - 2.3e-05 24.5 0.7 1.4 8.8 0.0 4.3 3 1 0 4 4 4 1 AAA domain AAA_25 PF13481.1 EME82531.1 - 3.2e-05 23.4 0.1 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EME82531.1 - 4.1e-05 23.0 0.7 0.1 12.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EME82531.1 - 0.00011 22.0 0.5 0.52 10.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EME82531.1 - 0.00017 22.0 0.3 0.45 11.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EME82531.1 - 0.0015 18.0 0.1 0.61 9.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 EME82531.1 - 0.0016 17.6 0.6 0.28 10.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EME82531.1 - 0.0046 17.3 0.2 0.36 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EME82531.1 - 0.0056 16.5 1.6 1.9 8.2 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 Dynamin_N PF00350.18 EME82531.1 - 0.0062 16.3 1.5 0.47 10.2 0.1 2.7 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 EME82531.1 - 0.011 15.8 2.5 0.86 9.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EME82531.1 - 0.019 13.9 0.0 2.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EME82531.1 - 0.079 12.3 2.5 1.8 7.9 0.1 2.7 2 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EME82531.1 - 0.19 12.5 0.2 13 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EME82531.1 - 0.3 10.7 0.9 23 4.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EME82531.1 - 1.5 8.4 4.5 1.6 8.3 0.1 2.8 3 0 0 3 3 3 0 NACHT domain SLT PF01464.15 EME82533.1 - 3.1e-08 33.1 0.7 4.2e-08 32.7 0.5 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain DUF1842 PF08896.5 EME82534.1 - 0.035 13.8 0.1 0.71 9.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1842) BetaGal_dom3 PF13363.1 EME82534.1 - 0.048 13.0 2.2 35 3.8 0.0 3.2 3 0 0 3 3 3 0 Beta-galactosidase, domain 3 Lipase_2 PF01674.13 EME82534.1 - 0.11 11.8 4.3 21 4.2 0.1 3.1 3 0 0 3 3 3 0 Lipase (class 2) Glyco_transf_28 PF03033.15 EME82537.1 - 1.4e-18 67.0 0.0 3.4e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EME82537.1 - 3.8e-07 29.0 0.0 6.5e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EME82537.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Pox_Ag35 PF03286.9 EME82537.1 - 0.091 12.2 0.1 0.091 12.2 0.0 3.0 3 0 0 3 3 3 0 Pox virus Ag35 surface protein tRNA-synt_2d PF01409.15 EME82539.1 - 9.3e-84 280.4 0.0 1.2e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EME82539.1 - 5.4e-05 22.1 4.7 0.00051 18.9 0.0 3.5 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EME82539.1 - 0.0018 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF2331 PF10093.4 EME82539.1 - 0.026 13.3 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) tRNA-synt_His PF13393.1 EME82539.1 - 0.048 12.7 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase ERp29 PF07749.7 EME82539.1 - 0.12 12.9 0.1 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Sugar_tr PF00083.19 EME82540.1 - 5.2e-88 295.5 17.9 6.2e-88 295.3 12.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82540.1 - 8e-13 47.8 37.2 3.3e-10 39.2 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3455 PF11937.3 EME82542.1 - 9.8e-32 110.3 0.7 1.2e-31 110.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CBM_14 PF01607.19 EME82543.1 - 9.4e-14 51.0 8.2 9.4e-14 51.0 5.7 1.6 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain WSC PF01822.14 EME82544.1 - 1.3e-15 57.0 9.5 3.4e-15 55.7 6.6 1.8 1 0 0 1 1 1 1 WSC domain Abhydrolase_5 PF12695.2 EME82544.1 - 5.3e-06 26.2 1.3 1.5e-05 24.7 0.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME82544.1 - 0.0003 20.7 0.2 0.0013 18.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME82544.1 - 0.041 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.5 EME82544.1 - 0.059 12.2 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Peptidase_M16 PF00675.15 EME82545.1 - 1.4e-58 196.8 0.1 5.5e-58 194.9 0.2 2.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EME82545.1 - 1.6e-39 135.4 0.1 5.8e-39 133.6 0.0 2.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain CybS PF05328.7 EME82546.1 - 7.4e-44 148.5 0.0 9.8e-44 148.2 0.0 1.1 1 0 0 1 1 1 1 CybS A_deaminase PF00962.17 EME82549.1 - 1.1e-37 129.7 0.0 3.3e-37 128.1 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase Ino80_Iec3 PF14612.1 EME82550.1 - 4.4e-45 154.5 0.1 5.7e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling HALZ PF02183.13 EME82550.1 - 0.0084 15.8 0.4 0.02 14.5 0.3 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper UPF0180 PF03698.8 EME82551.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) cNMP_binding PF00027.24 EME82555.1 - 6.2e-35 118.8 0.0 1.5e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EME82555.1 - 1.6e-09 36.8 0.5 15 6.0 0.1 8.1 8 1 1 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.28 EME82555.1 - 1.9e-07 30.1 2.7 14 6.1 0.0 8.0 7 3 0 7 7 7 1 Leucine Rich Repeat F-box PF00646.28 EME82555.1 - 7.6e-07 28.6 0.9 7.1e-06 25.5 0.0 2.9 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 EME82555.1 - 2.6e-06 27.1 0.1 0.0097 15.6 0.0 4.1 4 1 1 5 5 5 2 Leucine rich repeat F-box-like PF12937.2 EME82555.1 - 4.4e-06 26.3 0.0 1.5e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EME82555.1 - 8.4e-06 25.2 0.0 1.1 8.9 0.0 5.6 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EME82555.1 - 0.12 12.7 12.1 57 4.5 0.0 7.6 9 0 0 9 9 9 0 Leucine rich repeat Tyrosinase PF00264.15 EME82556.1 - 1.4e-44 152.8 0.2 2e-44 152.3 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Ycf66_N PF07444.6 EME82558.1 - 0.04 13.6 0.9 0.04 13.6 0.6 2.5 2 2 1 3 3 3 0 Ycf66 protein N-terminus DUF998 PF06197.8 EME82558.1 - 0.16 11.2 18.0 0.36 10.1 8.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Ferric_reduct PF01794.14 EME82558.1 - 1 9.4 10.0 2.2 8.3 7.0 1.6 1 0 0 1 1 1 0 Ferric reductase like transmembrane component TcpE PF12648.2 EME82558.1 - 5.1 7.2 7.0 0.48 10.5 0.3 2.5 3 0 0 3 3 3 0 TcpE family DUF4131 PF13567.1 EME82558.1 - 8.2 5.7 16.8 8 5.8 5.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Peptidase_S10 PF00450.17 EME82559.1 - 1.3e-69 235.3 2.4 1.9e-69 234.8 1.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UDPGP PF01704.13 EME82560.1 - 2.3e-53 181.2 0.0 3.1e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase zf-CCHC PF00098.18 EME82561.1 - 8.2e-44 145.5 59.9 1.4e-07 31.1 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EME82561.1 - 1.2e-08 34.5 47.0 0.064 12.9 0.8 7.0 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EME82561.1 - 0.00047 19.8 46.5 0.46 10.2 0.2 6.9 4 2 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 EME82561.1 - 0.094 12.2 0.5 0.094 12.2 0.3 7.1 4 2 3 7 7 7 0 Zinc knuckle Rad51 PF08423.6 EME82562.1 - 4.3e-23 81.5 1.2 4.9e-23 81.3 0.2 1.5 2 0 0 2 2 2 1 Rad51 KaiC PF06745.8 EME82562.1 - 0.0011 18.1 0.1 0.005 15.9 0.0 1.9 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 EME82562.1 - 0.0063 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EME82562.1 - 0.07 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NAD_binding_8 PF13450.1 EME82563.1 - 1.1e-11 44.5 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME82563.1 - 7.5e-11 41.7 0.1 7.5e-11 41.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME82563.1 - 3.6e-07 29.3 0.7 8.4e-07 28.1 0.9 1.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EME82563.1 - 4.5e-06 25.3 0.5 5.7e-06 25.0 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EME82563.1 - 1.5e-05 24.9 0.1 1.5e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME82563.1 - 3.8e-05 22.9 0.8 4.4e-05 22.7 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME82563.1 - 6e-05 22.2 0.7 7.2e-05 21.9 0.5 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EME82563.1 - 0.0009 18.2 1.6 0.0011 17.9 1.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME82563.1 - 0.002 18.2 0.1 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME82563.1 - 0.0025 16.9 0.0 0.0025 16.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EME82563.1 - 0.0031 17.8 0.7 0.0043 17.4 0.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME82563.1 - 0.0052 15.4 0.1 0.0052 15.4 0.1 1.0 1 0 0 1 1 1 1 Tryptophan halogenase IlvN PF07991.7 EME82563.1 - 0.039 13.3 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GIDA PF01134.17 EME82563.1 - 0.056 12.2 0.5 0.059 12.2 0.4 1.0 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EME82563.1 - 0.067 12.1 0.2 0.075 11.9 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME82563.1 - 0.07 12.9 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EME82563.1 - 0.13 12.0 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_2 PF00891.13 EME82564.1 - 3.7e-32 111.4 0.0 4.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.4 EME82564.1 - 0.001 18.5 0.0 0.0028 17.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EME82564.1 - 0.023 15.2 0.0 0.1 13.1 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EME82564.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase small domain SNF2_N PF00176.18 EME82565.1 - 2.8e-81 272.5 0.2 4.8e-81 271.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EME82565.1 - 2.2e-44 149.9 1.9 2.2e-44 149.9 1.3 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 EME82565.1 - 4.3e-31 107.6 2.5 4.3e-31 107.6 1.8 3.3 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 EME82565.1 - 5.6e-15 54.9 0.0 1.9e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME82565.1 - 2.8e-08 33.7 0.0 1.9e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EME82565.1 - 5.3e-06 26.0 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EME82565.1 - 0.019 14.9 0.0 1.4 9.0 0.0 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DEAD_2 PF06733.10 EME82565.1 - 0.023 14.1 0.2 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EME82565.1 - 0.026 14.4 0.1 0.11 12.3 0.1 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME82565.1 - 0.061 13.4 1.0 0.29 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-CCHC_5 PF14787.1 EME82566.1 - 0.014 14.8 1.5 0.014 14.8 1.1 3.6 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EME82566.1 - 0.015 14.9 1.4 0.015 14.9 1.0 5.1 3 1 2 5 5 5 0 Zinc knuckle zf-CCHC_4 PF14392.1 EME82566.1 - 0.65 9.7 24.7 0.54 9.9 1.3 4.7 4 0 0 4 4 4 0 Zinc knuckle DEAD PF00270.24 EME82567.1 - 1.2e-44 151.7 0.1 5.2e-44 149.7 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EME82567.1 - 2.4e-22 78.2 0.1 4.9e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EME82567.1 - 6e-21 74.1 0.0 1.9e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME82567.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME82567.1 - 0.17 11.9 0.4 1.2 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain DNA_RNApol_7kD PF03604.8 EME82569.1 - 0.095 12.1 3.1 6.9 6.2 0.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit RecR PF02132.10 EME82569.1 - 4.7 6.7 5.5 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 RecR protein HMG_box PF00505.14 EME82570.1 - 1.2e-15 57.5 0.8 3.8e-15 55.9 0.5 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EME82570.1 - 1.7e-07 31.5 0.4 5.5e-07 29.8 0.3 2.0 1 0 0 1 1 1 1 HMG-box domain GspL_C PF12693.2 EME82570.1 - 0.057 13.1 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Strep_SA_rep PF06696.6 EME82570.1 - 0.31 10.8 5.5 0.86 9.4 3.8 1.8 1 0 0 1 1 1 0 Streptococcal surface antigen repeat RRN3 PF05327.6 EME82570.1 - 2.7 6.0 4.6 3.6 5.5 3.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PufQ PF05398.6 EME82571.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 PufQ cytochrome subunit TrkA_C PF02080.16 EME82573.1 - 0.11 12.0 0.1 9.1 5.9 0.0 2.9 3 0 0 3 3 3 0 TrkA-C domain ATG2_CAD PF13329.1 EME82574.1 - 5.4e-34 117.0 0.1 9e-34 116.3 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EME82574.1 - 1.7e-24 85.7 0.0 4.3e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain adh_short PF00106.20 EME82575.1 - 4.4e-25 88.5 0.3 1.8e-24 86.5 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME82575.1 - 9.4e-12 44.9 0.1 2.6e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EME82575.1 - 6.7e-10 39.1 0.0 8.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME82575.1 - 0.015 14.7 0.1 0.04 13.3 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1322 PF07032.6 EME82575.1 - 0.15 12.2 0.0 0.69 10.1 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1322) RRM_1 PF00076.17 EME82577.1 - 6.5e-23 80.1 0.2 5.4e-13 48.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME82577.1 - 2.1e-20 72.4 0.1 2.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME82577.1 - 0.00062 19.5 0.2 0.38 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EME82578.1 - 1.3e-47 162.4 0.0 4.5e-47 160.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EME82579.1 - 0.0011 18.8 0.0 0.0021 18.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short PF00106.20 EME82580.1 - 6.3e-12 45.7 0.7 9.2e-12 45.1 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME82580.1 - 3.6e-06 26.7 0.1 5.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME82580.1 - 0.0012 18.7 0.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME82580.1 - 0.0048 16.3 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 EME82580.1 - 0.022 15.1 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 EME82580.1 - 0.071 12.7 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EME82580.1 - 0.071 12.9 1.0 0.16 11.7 0.4 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PBP1_TM PF14812.1 EME82581.1 - 5.9 7.2 12.2 30 5.0 0.1 3.3 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Xan_ur_permease PF00860.15 EME82582.1 - 0.0084 14.6 30.9 0.27 9.6 21.6 3.0 1 1 0 1 1 1 1 Permease family Nitrate_red_gam PF02665.9 EME82582.1 - 0.082 12.2 2.0 0.16 11.3 0.9 1.8 1 1 0 1 1 1 0 Nitrate reductase gamma subunit MFS_1 PF07690.11 EME82583.1 - 2.4e-41 141.6 33.7 4.6e-41 140.6 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME82583.1 - 1e-15 57.2 7.0 1e-15 57.2 4.9 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EME82583.1 - 0.0018 16.5 0.7 0.0028 15.9 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF389 PF04087.9 EME82583.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF389) HAMP PF00672.20 EME82584.1 - 2.5e-46 155.7 20.5 8.6e-09 35.4 0.3 6.8 6 0 0 6 6 6 6 HAMP domain Response_reg PF00072.19 EME82584.1 - 7e-28 96.8 0.6 1.5e-25 89.3 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EME82584.1 - 1.3e-27 95.7 1.4 2.7e-27 94.7 0.3 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME82584.1 - 2.2e-17 62.7 0.5 2.2e-17 62.7 0.3 4.4 7 0 0 7 7 7 1 His Kinase A (phospho-acceptor) domain NAAA-beta PF15508.1 EME82584.1 - 0.12 12.6 8.2 9.3 6.6 0.1 6.1 4 2 1 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2365 PF10157.4 EME82584.1 - 0.61 9.9 16.6 1 9.2 0.1 6.6 6 2 0 6 6 6 0 Uncharacterized conserved protein (DUF2365) Peptidase_M28 PF04389.12 EME82588.1 - 2e-16 60.2 0.0 3.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EME82588.1 - 7.3e-16 57.8 0.0 1.2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EME82588.1 - 0.0017 17.9 0.2 0.03 14.0 0.0 2.6 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EME82588.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EME82589.1 - 3.5e-41 141.0 32.7 3.5e-41 141.0 22.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EME82589.1 - 8 4.3 12.2 3.9 5.3 0.1 3.4 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.6 EME82590.1 - 1.9e-31 109.2 0.0 2.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 EME82590.1 - 8.9e-08 32.0 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME82590.1 - 1.6e-06 28.6 0.0 2.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME82590.1 - 2.3e-06 27.9 0.0 7.1e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME82590.1 - 2.5e-06 27.1 0.0 8.8e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME82590.1 - 2.9e-06 27.6 0.0 5.6e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME82590.1 - 0.00018 21.5 0.1 0.00047 20.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EME82590.1 - 0.00029 20.0 0.0 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.1 EME82590.1 - 0.00073 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EME82590.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.11 EME82591.1 - 2.4e-43 148.1 24.6 1e-42 146.1 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME82591.1 - 4.5e-14 51.8 6.1 4.5e-14 51.8 4.2 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EME82591.1 - 1.5e-11 43.2 5.2 2.6e-11 42.4 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EME82591.1 - 0.018 13.1 9.7 0.052 11.6 4.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3099 PF11298.3 EME82591.1 - 7.5 6.3 10.9 0.39 10.5 1.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DUF1228 PF06779.9 EME82591.1 - 8.3 6.5 14.2 0.044 13.8 1.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) ICL PF00463.16 EME82592.1 - 4.7e-281 932.5 1.1 5.3e-281 932.3 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EME82592.1 - 1.5e-11 43.9 0.0 4.3e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase FHA PF00498.21 EME82593.1 - 2.4e-13 50.0 0.0 4.6e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain RNA_pol_Rpb1_5 PF04998.12 EME82594.1 - 7.5e-87 291.0 0.0 1.4e-86 290.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EME82594.1 - 1.9e-84 283.7 0.0 3.3e-84 283.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EME82594.1 - 1e-65 220.7 0.2 2.1e-65 219.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EME82594.1 - 1.2e-31 109.5 0.0 4.5e-31 107.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EME82594.1 - 1.2e-27 95.7 0.4 5e-27 93.7 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 ADH_zinc_N PF00107.21 EME82595.1 - 1.9e-09 37.1 0.0 2.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EME82596.1 - 5.8e-47 160.4 0.0 7.6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME82596.1 - 5.7e-07 29.4 0.1 1.5e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME82596.1 - 7e-07 28.4 0.0 2.1e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME82596.1 - 1.5e-05 24.2 0.1 2.4e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EME82596.1 - 2e-05 23.2 0.0 3.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EME82596.1 - 2.1e-05 23.5 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EME82596.1 - 0.00014 22.1 0.1 0.00043 20.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME82596.1 - 0.0036 17.1 0.1 0.0066 16.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME82596.1 - 0.0043 17.1 0.0 0.0098 15.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME82596.1 - 0.0048 15.8 0.0 0.0089 14.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EME82596.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EME82596.1 - 0.024 13.7 0.2 0.042 12.9 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EME82596.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EME82596.1 - 0.043 12.6 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EME82596.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 2 0 0 2 2 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME82596.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME82596.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EME82596.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_11 PF14833.1 EME82597.1 - 2.2e-22 79.3 0.0 3.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EME82597.1 - 3.5e-21 75.7 0.1 5.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CMD PF02627.15 EME82598.1 - 1.2e-11 44.2 0.0 9.8e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family FAD_binding_4 PF01565.18 EME82599.1 - 2.4e-29 101.5 0.0 3.8e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Alpha-amylase PF00128.19 EME82600.1 - 8.8e-64 215.8 0.7 1.4e-63 215.2 0.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EME82600.1 - 2e-26 91.8 0.2 4.5e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Aminotran_5 PF00266.14 EME82600.1 - 0.14 10.8 0.1 0.45 9.1 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Pkinase PF00069.20 EME82601.1 - 3.5e-62 209.9 0.0 4.4e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82601.1 - 1e-39 136.1 0.0 1.4e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82601.1 - 2.9e-05 23.1 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EME82601.1 - 0.0047 16.5 0.0 0.0076 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EME82601.1 - 0.055 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EME82601.1 - 0.067 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH2_2 PF14633.1 EME82602.1 - 3.2e-79 265.0 0.6 9.2e-79 263.5 0.4 1.8 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EME82602.1 - 1.1e-39 135.0 5.5 6e-39 132.6 3.8 2.4 1 0 0 1 1 1 1 Death-like domain of SPT6 HHH_7 PF14635.1 EME82602.1 - 2e-31 108.1 0.0 4.6e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EME82602.1 - 4.8e-30 104.1 0.0 1.5e-29 102.4 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EME82602.1 - 1.5e-22 79.5 27.8 1.5e-22 79.5 19.3 5.0 5 0 0 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EME82602.1 - 3.9e-14 52.6 1.2 1.2e-13 51.1 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EME82602.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EME82602.1 - 0.0031 17.4 0.0 0.011 15.6 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.18 EME82602.1 - 0.018 15.0 0.0 0.085 12.9 0.0 2.2 2 0 0 2 2 2 0 S1 RNA binding domain IFRD PF05004.8 EME82604.1 - 2.2e-40 138.6 1.1 3.4e-40 138.0 0.8 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) TAFII28 PF04719.9 EME82604.1 - 0.16 11.7 4.8 7.1 6.4 0.2 3.3 2 1 1 3 3 3 0 hTAFII28-like protein conserved region NMT1 PF09084.6 EME82605.1 - 2.8e-75 252.6 0.0 4.2e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EME82605.1 - 2.6e-07 30.2 0.0 0.092 12.1 0.0 3.2 2 1 0 3 3 3 3 NMT1-like family Lipoxygenase PF00305.14 EME82607.1 - 2.4e-42 144.8 0.1 1.4e-36 125.7 0.1 3.0 1 1 1 2 2 2 2 Lipoxygenase ubiquitin PF00240.18 EME82608.1 - 1.3e-05 24.4 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EME82608.1 - 0.033 14.7 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Aspzincin_M35 PF14521.1 EME82610.1 - 0.038 14.5 0.1 0.097 13.1 0.1 1.7 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase WD40 PF00400.27 EME82611.1 - 9.2e-28 95.0 0.2 1.8e-08 33.9 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Gmad1 PF10647.4 EME82611.1 - 3.4e-06 26.6 2.1 9.4e-06 25.2 0.2 2.0 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EME82611.1 - 0.0055 16.1 0.9 0.062 12.7 0.6 2.3 1 1 1 2 2 2 1 PQQ-like domain eIF2A PF08662.6 EME82611.1 - 0.036 13.7 0.2 1.7 8.2 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EME82611.1 - 0.095 11.4 0.0 0.37 9.4 0.0 1.9 1 1 0 1 1 1 0 Nup133 N terminal like FTHFS PF01268.14 EME82612.1 - 1.1e-255 848.9 1.7 1.7e-255 848.3 1.2 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EME82612.1 - 2e-67 225.2 1.7 4.9e-67 223.9 1.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EME82612.1 - 5.2e-38 129.6 2.0 1.2e-37 128.4 1.4 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain LNS2 PF08235.8 EME82613.1 - 8e-70 233.4 0.0 1.3e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EME82613.1 - 4.7e-40 135.6 0.0 1e-39 134.6 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region DMPK_coil PF08826.5 EME82613.1 - 0.16 11.8 0.7 0.35 10.8 0.5 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like MBF1 PF08523.5 EME82614.1 - 6.6e-23 80.5 1.7 6.6e-23 80.5 1.1 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EME82614.1 - 0.0019 17.9 0.0 0.0046 16.7 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix Fungal_trans PF04082.13 EME82615.1 - 2.6e-27 95.3 0.6 4.2e-27 94.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME82615.1 - 0.004 17.0 3.7 0.0082 16.0 2.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADIP PF11559.3 EME82621.1 - 2.8e-35 121.4 16.1 2.8e-35 121.4 11.1 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EME82621.1 - 0.41 9.0 8.3 0.74 8.2 5.7 1.3 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EME82621.1 - 1.5 7.7 14.2 3.5 6.5 9.8 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EME82621.1 - 1.9 8.5 12.5 1.6 8.7 6.5 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.7 EME82621.1 - 5.1 5.4 5.7 9.3 4.5 4.0 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERM PF00769.14 EME82621.1 - 5.7 6.4 26.1 0.071 12.6 11.6 2.5 3 1 0 3 3 3 0 Ezrin/radixin/moesin family IncA PF04156.9 EME82621.1 - 6 6.4 19.6 21 4.6 11.0 3.0 3 0 0 3 3 3 0 IncA protein Scytalone_dh PF02982.9 EME82622.1 - 1e-85 285.2 1.1 1.2e-85 284.9 0.8 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EME82622.1 - 6.8e-06 26.0 0.1 9.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain RRM_1 PF00076.17 EME82624.1 - 2.1e-46 155.3 0.0 8.3e-17 60.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME82624.1 - 7.3e-27 93.1 0.0 2e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME82624.1 - 3.9e-21 74.6 0.0 2.7e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME82624.1 - 5.2e-06 26.2 0.0 0.0001 22.0 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EME82624.1 - 3.2e-05 23.6 0.0 0.0089 15.7 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 EME82624.1 - 0.075 12.5 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain 14-3-3 PF00244.15 EME82625.1 - 2.5e-116 386.7 6.9 2.9e-116 386.5 4.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TerB PF05099.8 EME82625.1 - 0.033 13.9 0.3 0.1 12.3 0.2 1.8 1 0 0 1 1 1 0 Tellurite resistance protein TerB DUF837 PF05769.6 EME82625.1 - 0.058 12.9 3.3 2.5 7.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Peptidase_M17_N PF02789.12 EME82625.1 - 0.084 12.6 0.1 0.5 10.1 0.0 2.3 1 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain BSP_II PF05432.6 EME82626.1 - 0.36 10.0 12.3 0.038 13.2 4.7 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Glyco_transf_28 PF03033.15 EME82628.1 - 1.6e-18 66.7 0.0 3.9e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EME82628.1 - 1.9e-06 26.7 0.0 3.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EME82628.1 - 0.00056 19.6 0.7 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EME82628.1 - 0.0028 17.7 0.0 0.0098 16.0 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain UIM PF02809.15 EME82628.1 - 0.003 16.9 1.9 0.003 16.9 1.3 3.9 3 0 0 3 3 3 2 Ubiquitin interaction motif Mur_ligase PF01225.20 EME82628.1 - 0.11 12.5 0.1 0.38 10.8 0.1 1.9 1 0 0 1 1 1 0 Mur ligase family, catalytic domain SBDS PF01172.13 EME82631.1 - 3.4e-24 84.4 0.2 4e-24 84.2 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein VOMI PF03762.12 EME82631.1 - 0.049 13.5 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) RhoGEF PF00621.15 EME82632.1 - 4.1e-16 59.3 0.1 9.7e-13 48.3 0.0 2.3 1 1 1 2 2 2 2 RhoGEF domain PH PF00169.24 EME82632.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Drc1-Sld2 PF11719.3 EME82633.1 - 0.011 14.9 13.3 0.022 13.8 9.2 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein DUF1140 PF06600.6 EME82633.1 - 0.038 14.1 0.2 0.081 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) Mei5 PF10376.4 EME82633.1 - 0.2 11.1 20.9 3.1 7.2 14.5 2.2 1 1 0 1 1 1 0 Double-strand recombination repair protein Wbp11 PF09429.5 EME82633.1 - 0.45 10.5 10.0 0.46 10.5 1.7 2.6 2 0 0 2 2 2 0 WW domain binding protein 11 U1snRNP70_N PF12220.3 EME82633.1 - 1.6 9.1 7.1 0.3 11.4 1.8 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal GreA_GreB_N PF03449.10 EME82633.1 - 2.2 8.3 8.1 0.35 10.9 0.1 2.8 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal DUF848 PF05852.6 EME82633.1 - 4.1 7.2 9.5 0.17 11.7 1.0 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3435 PF11917.3 EME82633.1 - 9.8 4.7 8.4 11 4.5 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) SR-25 PF10500.4 EME82633.1 - 9.8 5.5 11.1 0.27 10.6 1.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TetR_N PF00440.18 EME82635.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family NAD_binding_1 PF00175.16 EME82636.1 - 3.3e-11 43.7 0.0 5.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME82636.1 - 6.7e-09 35.7 0.0 1.9e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EME82636.1 - 1.5e-07 31.7 0.2 2.3e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Globin NAD_binding_6 PF08030.7 EME82636.1 - 3.6e-05 23.6 0.0 0.0039 17.0 0.0 2.8 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EME82636.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Protoglobin FAD_binding_8 PF08022.7 EME82636.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain BRICHOS PF04089.9 EME82636.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 BRICHOS domain RNase_PH PF01138.16 EME82637.1 - 1.5e-34 119.1 0.1 2.4e-34 118.4 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EME82637.1 - 0.04 13.8 0.2 0.083 12.8 0.1 1.6 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 Cyclase PF04199.8 EME82638.1 - 9.3e-13 48.2 0.2 1.5e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase His_Phos_1 PF00300.17 EME82642.1 - 3.9e-17 62.8 0.0 6.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Claudin_2 PF13903.1 EME82646.1 - 0.01 15.5 3.1 0.014 15.1 1.8 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.7 EME82646.1 - 0.28 11.1 0.2 0.28 11.1 0.1 2.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Fzo_mitofusin PF04799.8 EME82646.1 - 0.38 10.1 3.0 0.18 11.1 0.6 1.5 1 1 1 2 2 2 0 fzo-like conserved region Peptidase_S10 PF00450.17 EME82648.1 - 6e-89 299.0 0.0 7.8e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1408 PF07193.6 EME82649.1 - 0.019 14.4 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) ZZ PF00569.12 EME82650.1 - 1.7e-20 72.2 53.4 1e-05 24.9 7.1 4.3 4 0 0 4 4 4 4 Zinc finger, ZZ type zf-DHHC PF01529.15 EME82650.1 - 0.00093 18.6 2.8 0.051 12.9 0.0 2.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Lipoprotein_17 PF04200.7 EME82650.1 - 0.063 13.4 0.1 5.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Lipoprotein associated domain Atg14 PF10186.4 EME82650.1 - 0.081 11.8 7.5 0.2 10.5 5.2 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_B PF00430.13 EME82650.1 - 0.11 12.3 14.7 0.23 11.2 10.2 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1700 PF08006.6 EME82650.1 - 0.94 8.7 3.6 1.5 8.0 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) LMBR1 PF04791.11 EME82650.1 - 8.8 4.7 4.8 13 4.1 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Btz PF09405.5 EME82651.1 - 2.7e-20 72.7 3.6 2.7e-20 72.7 2.5 2.5 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Sec1 PF00995.18 EME82653.1 - 1.9e-158 528.6 0.0 2.2e-158 528.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2813 PF11398.3 EME82653.1 - 0.0086 15.1 0.0 0.03 13.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) zf-CCCH PF00642.19 EME82654.1 - 6.4e-05 22.5 3.0 0.00011 21.8 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Asp PF00026.18 EME82655.1 - 3.4e-50 171.0 4.6 8.9e-49 166.4 3.2 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EME82655.1 - 4.5e-07 30.2 5.1 4.2e-05 23.9 0.1 2.9 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EME82655.1 - 0.0001 22.2 0.7 0.00097 19.1 0.5 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EME82655.1 - 0.06 12.8 0.1 0.82 9.1 0.0 2.8 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal V-ATPase_G PF03179.10 EME82657.1 - 2e-30 105.1 16.3 2.3e-30 105.0 11.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit MMR_HSR1_C PF08438.5 EME82657.1 - 0.072 13.3 4.0 0.11 12.7 2.8 1.4 1 1 0 1 1 1 0 GTPase of unknown function C-terminal DUF2203 PF09969.4 EME82657.1 - 0.23 11.6 4.6 0.29 11.3 3.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Rhabdo_ncap PF00945.13 EME82657.1 - 0.24 9.9 4.2 0.25 9.8 2.9 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Z1 PF10593.4 EME82657.1 - 0.25 10.5 3.2 0.27 10.3 2.2 1.1 1 0 0 1 1 1 0 Z1 domain DUF763 PF05559.6 EME82657.1 - 0.26 10.2 2.7 0.27 10.1 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Vfa1 PF08432.5 EME82657.1 - 0.32 11.0 14.4 0.37 10.7 10.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 OmpH PF03938.9 EME82657.1 - 0.54 10.1 12.8 0.68 9.8 8.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2201_N PF13203.1 EME82657.1 - 0.67 9.0 5.0 0.71 8.9 3.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2422 PF10337.4 EME82657.1 - 0.68 8.6 3.3 0.76 8.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TRAPP PF04051.11 EME82657.1 - 0.71 9.3 3.0 0.79 9.2 2.0 1.3 1 1 0 1 1 1 0 Transport protein particle (TRAPP) component DRY_EERY PF09750.4 EME82657.1 - 0.82 9.7 7.3 1.1 9.4 5.1 1.1 1 0 0 1 1 1 0 Alternative splicing regulator U79_P34 PF03064.11 EME82657.1 - 0.88 9.0 8.7 0.99 8.8 6.1 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM91_C PF14648.1 EME82657.1 - 0.95 8.2 4.5 1.1 8.0 3.1 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF4612 PF15389.1 EME82657.1 - 1.1 9.8 11.5 1.5 9.4 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Borrelia_P83 PF05262.6 EME82657.1 - 1.4 7.0 15.5 1.6 6.9 10.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 EME82657.1 - 2 6.3 7.7 2.1 6.2 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RRF PF01765.14 EME82657.1 - 2.5 7.5 12.2 3.1 7.2 8.5 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Atg14 PF10186.4 EME82657.1 - 2.9 6.7 10.7 3.4 6.5 7.4 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HSP70 PF00012.15 EME82657.1 - 4 5.2 10.2 4.4 5.0 7.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Selenoprotein_S PF06936.6 EME82657.1 - 4.3 6.8 9.2 5.1 6.5 6.3 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1912 PF08930.5 EME82657.1 - 4.3 7.4 6.9 1.6 8.8 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1912) 14-3-3 PF00244.15 EME82657.1 - 5.1 6.1 11.7 0.32 10.0 2.8 1.9 1 1 1 2 2 2 0 14-3-3 protein SAPS PF04499.10 EME82657.1 - 5.2 5.5 8.0 5.7 5.4 5.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3987 PF13148.1 EME82657.1 - 7.2 5.0 10.5 7.9 4.9 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3464 PF11947.3 EME82657.1 - 7.5 5.9 8.0 12 5.3 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) Pmp3 PF01679.12 EME82658.1 - 2.9e-11 42.8 6.3 4.4e-11 42.2 4.3 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UDG PF03167.14 EME82660.1 - 1.2e-21 76.7 0.0 1.5e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily AAA_12 PF13087.1 EME82661.1 - 4.2e-16 58.9 0.3 6e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EME82661.1 - 0.009 16.1 0.1 0.049 13.7 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UBA_4 PF14555.1 EME82661.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain adh_short PF00106.20 EME82662.1 - 2.5e-15 56.7 0.0 4.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase DUF460 PF04312.8 EME82662.1 - 1.4e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF460) KR PF08659.5 EME82662.1 - 7.1e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EME82662.1 - 0.067 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain GRASP55_65 PF04495.9 EME82663.1 - 1.2e-44 151.6 0.0 1.8e-42 144.5 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ PF00595.19 EME82663.1 - 0.028 14.6 0.0 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) HABP4_PAI-RBP1 PF04774.10 EME82665.1 - 0.14 12.6 5.9 3.2 8.3 0.2 2.9 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family p450 PF00067.17 EME82666.1 - 2e-66 224.4 0.0 2.6e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LTD PF00932.14 EME82666.1 - 0.04 13.9 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain Acyl-CoA_dh_1 PF00441.19 EME82667.1 - 1.2e-33 116.3 1.5 1.7e-33 115.8 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME82667.1 - 8.7e-22 76.3 0.7 1.7e-21 75.4 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME82667.1 - 2e-13 50.9 0.0 7.8e-13 48.9 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME82667.1 - 2.7e-07 30.9 0.4 4.2e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RNA_pol_Rpb2_6 PF00562.23 EME82668.1 - 1.6e-125 418.8 0.1 2.9e-125 418.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME82668.1 - 1.5e-57 193.7 0.1 2.4e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EME82668.1 - 2.5e-44 150.9 0.2 5.4e-44 149.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EME82668.1 - 1.9e-28 98.5 0.0 4.6e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EME82668.1 - 4.8e-25 87.1 0.6 1.3e-24 85.7 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EME82668.1 - 4.9e-23 80.6 0.1 9.9e-23 79.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EME82668.1 - 6.3e-22 77.2 0.3 1.4e-21 76.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ABM PF03992.11 EME82669.1 - 1.2e-07 31.6 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3917 PF13055.1 EME82670.1 - 0.0083 16.3 2.1 0.0099 16.1 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3917) Pox_polyA_pol PF03296.8 EME82670.1 - 0.03 13.8 0.6 0.035 13.6 0.4 1.1 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain MFS_1 PF07690.11 EME82671.1 - 7.1e-25 87.4 11.6 9.2e-25 87.0 8.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME82671.1 - 2e-10 39.8 4.1 2.8e-10 39.3 2.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EME82671.1 - 1e-05 23.9 2.5 1.4e-05 23.4 1.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_1 PF00175.16 EME82672.1 - 5.7e-29 100.8 0.0 9.2e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME82672.1 - 1.3e-23 82.9 0.0 2.9e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EME82672.1 - 4.3e-08 33.2 0.0 0.00044 20.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EME82672.1 - 2e-05 24.5 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain zf-RING_2 PF13639.1 EME82673.1 - 2.5e-12 46.4 4.9 4.7e-12 45.5 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME82673.1 - 1.2e-07 31.7 0.9 2.4e-07 30.7 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME82673.1 - 9.4e-06 25.1 2.8 1.8e-05 24.3 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME82673.1 - 1.8e-05 24.6 3.5 3.7e-05 23.6 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME82673.1 - 3.4e-05 23.4 3.4 5.9e-05 22.7 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME82673.1 - 0.0003 20.5 0.8 0.00073 19.3 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EME82673.1 - 0.00042 19.9 2.6 0.00077 19.0 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EME82673.1 - 0.1 12.3 3.4 0.19 11.4 2.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EME82673.1 - 0.22 11.5 1.2 0.44 10.5 0.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EME82673.1 - 0.37 10.4 2.3 0.72 9.4 1.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EME82673.1 - 0.51 10.3 2.2 1.5 8.8 1.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Ada3 PF10198.4 EME82674.1 - 3.1e-33 114.3 0.1 3.1e-33 114.3 0.1 2.3 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-AN1 PF01428.11 EME82676.1 - 0.23 11.3 8.8 14 5.6 0.0 2.7 2 1 0 2 2 2 0 AN1-like Zinc finger DUF2404 PF10296.4 EME82677.1 - 0.012 15.7 0.0 0.066 13.3 0.0 2.1 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) PDZ PF00595.19 EME82679.1 - 1.7e-07 31.3 0.0 3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EME82679.1 - 3.7e-07 29.9 0.0 9.5e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EME82679.1 - 7.2e-06 26.0 0.0 2.1e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain adh_short_C2 PF13561.1 EME82681.1 - 3e-22 79.5 0.1 3.5e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME82681.1 - 9.1e-20 71.2 0.2 1.2e-19 70.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 EME82681.1 - 0.049 13.6 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Polysacc_deac_1 PF01522.16 EME82682.1 - 1.4e-23 82.8 0.0 2.4e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EME82682.1 - 0.085 11.8 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Methyltransf_24 PF13578.1 EME82682.1 - 0.11 13.3 0.1 1.9 9.3 0.1 2.8 1 1 1 2 2 2 0 Methyltransferase domain HTH_39 PF14090.1 EME82682.1 - 0.14 11.6 0.0 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M20 PF01546.23 EME82683.1 - 2.6e-31 108.5 0.0 4.4e-31 107.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME82683.1 - 3e-13 49.4 0.0 5.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3328 PF11807.3 EME82686.1 - 6.1e-25 88.1 5.0 6.1e-25 88.1 3.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Orthopox_F6 PF06601.7 EME82690.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus F6 protein DUF3328 PF11807.3 EME82690.1 - 0.07 12.7 3.1 0.12 12.0 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EME82692.1 - 3.4e-31 108.6 0.1 4e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Nop PF01798.13 EME82693.1 - 3.2e-54 182.3 1.2 9.1e-54 180.8 0.8 1.9 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EME82693.1 - 2.4e-27 94.4 0.1 4.1e-27 93.7 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EME82693.1 - 2e-21 75.8 3.0 8e-21 73.9 2.1 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF760 PF05542.6 EME82693.1 - 0.025 14.7 0.1 0.24 11.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF760) Actin PF00022.14 EME82694.1 - 1.2e-22 79.8 0.0 4.3e-19 68.1 0.0 3.0 2 1 0 2 2 2 2 Actin Peptidase_S8 PF00082.17 EME82695.1 - 2.1e-45 155.0 5.2 3.1e-45 154.5 3.6 1.1 1 0 0 1 1 1 1 Subtilase family MatE PF01554.13 EME82696.1 - 4e-08 33.0 19.2 2.2e-06 27.4 1.4 3.7 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.1 EME82696.1 - 0.00029 20.6 2.3 0.00029 20.6 1.6 3.6 4 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF2628 PF10947.3 EME82696.1 - 0.025 14.3 1.1 0.025 14.3 0.7 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2628) DUF4630 PF15443.1 EME82696.1 - 0.2 11.4 0.9 10 5.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4630) DUF1289 PF06945.8 EME82697.1 - 0.018 14.5 0.2 0.027 13.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) RGS PF00615.14 EME82698.1 - 1.1e-11 44.8 0.0 3.8e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF3337 PF11816.3 EME82698.1 - 0.06 12.7 0.8 0.081 12.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Claudin_2 PF13903.1 EME82698.1 - 1.3 8.6 5.5 0.22 11.1 0.7 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction O-antigen_lig PF13425.1 EME82698.1 - 4 7.4 9.2 9.3 6.2 6.4 1.6 1 1 0 1 1 1 0 O-antigen ligase like membrane protein Glyco_hydro_3 PF00933.16 EME82699.1 - 1.8e-95 319.4 0.0 2.7e-95 318.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME82699.1 - 6.6e-55 186.0 0.4 4.2e-54 183.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME82699.1 - 6e-17 61.3 0.2 1.6e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PAF-AH_p_II PF03403.8 EME82701.1 - 1.2e-44 152.1 0.0 3e-40 137.6 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EME82701.1 - 8.7e-09 35.2 0.1 3.2e-08 33.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME82701.1 - 1.5e-06 28.2 1.2 4.7e-06 26.6 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME82701.1 - 0.00021 21.0 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EME82701.1 - 0.0012 17.7 0.0 0.0047 15.8 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME82701.1 - 0.0068 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Ras PF00071.17 EME82702.1 - 8.7e-41 139.0 0.0 6.3e-40 136.2 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EME82702.1 - 6e-14 52.5 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME82702.1 - 4.8e-10 38.9 0.0 2.9e-08 33.1 0.0 3.0 2 2 1 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME82702.1 - 1.8e-07 30.7 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME82702.1 - 9.5e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EME82702.1 - 0.00025 20.2 0.1 0.00052 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EME82702.1 - 0.00037 19.7 0.0 0.0012 18.0 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EME82702.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME82702.1 - 0.0062 16.6 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 EME82702.1 - 0.0069 15.8 0.0 0.074 12.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EME82702.1 - 0.0087 15.7 0.1 0.063 12.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 EME82702.1 - 0.0096 16.2 0.2 0.043 14.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SRPRB PF09439.5 EME82702.1 - 0.013 14.7 0.0 0.051 12.7 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EME82702.1 - 0.016 15.1 0.2 0.076 13.0 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 EME82702.1 - 0.04 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EME82702.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME82702.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME82702.1 - 0.12 12.5 0.1 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EME82702.1 - 0.17 10.5 0.0 0.67 8.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF218 PF02698.12 EME82705.1 - 7.5e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Chitin_synth_1 PF01644.12 EME82706.1 - 2.1e-67 226.0 0.0 3e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EME82706.1 - 6e-28 96.3 0.0 1.4e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EME82706.1 - 9.3e-25 86.9 0.1 6.2e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EME82706.1 - 3.3e-11 43.2 0.2 3.3e-11 43.2 0.2 2.9 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EME82706.1 - 1e-07 31.9 0.0 2.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PLDc_2 PF13091.1 EME82707.1 - 2e-17 63.0 0.0 3.2e-12 46.2 0.0 2.4 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EME82707.1 - 0.004 16.9 0.3 0.48 10.3 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EME82707.1 - 0.1 11.5 0.3 0.63 8.9 0.0 2.3 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB Glyco_hydro_20 PF00728.17 EME82708.1 - 2e-42 145.6 0.8 2.7e-42 145.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EME82708.1 - 4e-06 27.3 0.0 1e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 NAD_binding_10 PF13460.1 EME82709.1 - 1e-19 71.2 0.9 1.4e-19 70.7 0.6 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME82709.1 - 1.1e-15 57.7 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME82709.1 - 7.5e-09 34.8 0.4 0.0014 17.5 0.2 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 EME82709.1 - 1.2e-08 34.5 1.9 1.3e-08 34.4 0.7 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EME82709.1 - 6.7e-08 31.5 0.3 2.5e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EME82709.1 - 0.00034 20.5 0.3 0.00063 19.7 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EME82709.1 - 0.00062 18.8 0.3 0.00094 18.2 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 EME82709.1 - 0.0015 17.9 0.1 0.0039 16.6 0.1 1.7 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EME82709.1 - 0.0045 16.3 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.15 EME82709.1 - 0.008 16.0 0.2 0.016 15.0 0.2 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EME82709.1 - 0.021 14.6 0.1 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.7 EME82709.1 - 0.043 12.7 0.2 0.1 11.4 0.1 1.7 1 1 1 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.19 EME82709.1 - 0.075 13.3 0.4 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EME82709.1 - 0.17 11.7 2.8 0.57 10.0 1.8 2.0 1 1 0 1 1 1 0 short chain dehydrogenase DUF2837 PF10997.3 EME82711.1 - 0.0098 15.0 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2837) Myc_target_1 PF15179.1 EME82711.1 - 0.01 15.4 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 0 Myc target protein 1 SNARE_assoc PF09335.6 EME82711.1 - 0.044 13.9 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF1191 PF06697.7 EME82711.1 - 0.1 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PALP PF00291.20 EME82712.1 - 3.7e-66 223.4 0.6 4.6e-66 223.1 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lact_bio_phlase PF09508.5 EME82713.1 - 0.17 9.4 0.0 0.23 9.0 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase Senescence PF06911.7 EME82716.1 - 8.5e-43 146.1 4.2 1.4e-42 145.4 2.9 1.3 1 0 0 1 1 1 1 Senescence-associated protein TrkH PF02386.11 EME82717.1 - 9.1e-89 297.4 6.0 2.2e-83 279.7 0.9 2.0 2 0 0 2 2 2 2 Cation transport protein SieB PF14163.1 EME82717.1 - 0.0029 17.1 1.0 0.033 13.7 0.3 2.5 2 0 0 2 2 2 1 Superinfection exclusion protein B DUF1509 PF07420.6 EME82717.1 - 0.41 9.8 3.0 0.64 9.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Pkinase PF00069.20 EME82718.1 - 2.3e-06 26.9 0.0 2.6e-05 23.4 0.0 2.7 3 1 0 3 3 3 1 Protein kinase domain p450 PF00067.17 EME82719.1 - 9.5e-49 166.1 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERAP1_C PF11838.3 EME82719.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain RRM_1 PF00076.17 EME82720.1 - 0.0016 17.9 0.0 0.057 13.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.7 EME82720.1 - 0.0027 17.9 0.1 0.0027 17.9 0.1 4.2 3 1 0 3 3 3 1 Nucleopolyhedrovirus P10 protein RRM_5 PF13893.1 EME82720.1 - 0.0091 15.8 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_1_2 PF00155.16 EME82721.1 - 1.6e-59 201.7 0.0 1.8e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EME82721.1 - 0.0021 16.3 0.0 0.0036 15.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EME82721.1 - 0.009 14.7 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_MocR PF12897.2 EME82721.1 - 0.012 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase CTP_transf_1 PF01148.15 EME82723.1 - 1.2e-17 64.4 5.3 1e-15 58.0 0.8 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF3984 PF13136.1 EME82723.1 - 0.13 11.4 2.8 0.2 10.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Acyl-CoA_dh_1 PF00441.19 EME82724.1 - 2.7e-41 141.1 5.3 4.3e-41 140.4 3.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME82724.1 - 2.1e-27 95.9 0.6 4.7e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EME82724.1 - 3.5e-19 68.0 0.0 7.6e-19 66.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EME82724.1 - 4.8e-17 62.4 2.2 8.4e-17 61.6 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EME82724.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal GMC_oxred_N PF00732.14 EME82725.1 - 1.6e-51 175.2 0.1 2.8e-51 174.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME82725.1 - 9e-31 107.1 0.0 1.6e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EME82725.1 - 9.4e-05 21.4 0.1 0.00098 18.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME82725.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME82725.1 - 0.0018 17.1 0.1 0.18 10.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EME82725.1 - 0.004 16.1 0.0 0.0068 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME82725.1 - 0.015 15.1 0.0 4.4 7.1 0.0 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME82725.1 - 0.026 14.5 0.2 13 5.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME82725.1 - 0.047 13.6 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 EME82725.1 - 0.14 11.2 0.7 0.55 9.2 0.0 2.2 2 1 0 2 2 2 0 Thi4 family NDUF_B8 PF05821.6 EME82726.1 - 7e-06 25.8 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EME82727.1 - 3.1e-68 229.7 0.4 5e-68 229.0 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME82727.1 - 1.2e-12 47.5 0.0 3.3e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME82727.1 - 5.9e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 EME82727.1 - 0.0067 16.1 3.2 0.0067 16.1 2.2 3.7 2 1 1 3 3 3 1 HSA CFEM PF05730.6 EME82729.1 - 0.00033 20.4 16.1 0.00072 19.3 11.1 1.6 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.4 EME82729.1 - 1.8 7.1 7.8 2.4 6.7 5.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 EME82730.1 - 0.35 9.0 2.2 0.31 9.2 1.5 1.2 1 0 0 1 1 1 0 Transmembrane protein UQ_con PF00179.21 EME82731.1 - 2e-51 173.1 0.0 2.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME82731.1 - 1e-05 25.3 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME82731.1 - 0.064 13.1 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 RWD domain Clr2 PF10383.4 EME82732.1 - 7.4e-12 45.4 0.0 9.7e-11 41.8 0.0 2.4 3 0 0 3 3 3 1 Transcription-silencing protein Clr2 RskA PF10099.4 EME82733.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2403 PF10290.4 EME82733.1 - 0.089 12.9 0.4 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) Na_H_Exchanger PF00999.16 EME82734.1 - 1.1e-52 178.9 22.0 1.3e-52 178.5 15.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EME82734.1 - 0.015 15.2 0.7 0.015 15.2 0.5 3.3 4 0 0 4 4 4 0 YrhC-like protein gpUL132 PF11359.3 EME82734.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Methyltransf_31 PF13847.1 EME82736.1 - 8.9e-29 100.0 0.0 1.3e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME82736.1 - 1.8e-21 76.4 0.0 4e-21 75.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME82736.1 - 1e-20 74.4 0.0 6.5e-20 71.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME82736.1 - 1.8e-17 63.6 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME82736.1 - 6e-15 55.3 0.0 1.3e-14 54.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME82736.1 - 9.5e-15 54.3 0.0 1.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME82736.1 - 1.5e-12 47.7 0.0 4.3e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME82736.1 - 1.6e-12 46.8 0.0 1.1e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EME82736.1 - 9.1e-11 41.8 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME82736.1 - 7.3e-10 38.4 0.0 1.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EME82736.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EME82736.1 - 3e-07 30.0 0.0 4.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW GCD14 PF08704.5 EME82736.1 - 1.7e-05 24.4 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit tRNA_U5-meth_tr PF05958.6 EME82736.1 - 7.4e-05 21.5 0.0 0.0001 21.1 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_3 PF01596.12 EME82736.1 - 0.00059 18.9 0.0 0.0013 17.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 EME82736.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EME82736.1 - 0.0021 17.6 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.1 EME82736.1 - 0.0025 17.5 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EME82736.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 EME82736.1 - 0.0066 16.0 0.0 0.014 14.9 0.0 1.5 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.6 EME82736.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DOT1 PF08123.8 EME82736.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.9 EME82736.1 - 0.016 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.10 EME82736.1 - 0.019 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.14 EME82736.1 - 0.045 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase CmcI PF04989.7 EME82736.1 - 0.045 13.0 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase CMAS PF02353.15 EME82736.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-LITAF-like PF10601.4 EME82737.1 - 0.038 13.8 0.3 0.076 12.8 0.2 1.5 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain ABC_tran PF00005.22 EME82738.1 - 1.5e-33 116.0 0.0 3.9e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EME82738.1 - 1e-27 97.2 11.5 2.2e-27 96.2 8.0 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EME82738.1 - 2.9e-07 29.9 0.3 3.9e-06 26.2 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME82738.1 - 6.3e-05 23.0 1.1 0.11 12.4 0.1 2.8 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EME82738.1 - 0.00061 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME82738.1 - 0.00097 18.3 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME82738.1 - 0.0039 17.0 0.3 0.043 13.7 0.2 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EME82738.1 - 0.011 15.2 0.3 0.035 13.6 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EME82738.1 - 0.015 15.4 0.4 0.14 12.3 0.3 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME82738.1 - 0.069 12.8 0.3 1.4 8.6 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EME82738.1 - 0.13 11.9 0.6 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 NTPase RNase_H PF00075.19 EME82740.1 - 0.00025 21.3 0.0 0.00025 21.3 0.0 1.1 1 0 0 1 1 1 1 RNase H DUF4536 PF15055.1 EME82742.1 - 0.00021 21.2 0.3 0.00041 20.3 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) DUF4588 PF15251.1 EME82743.1 - 0.014 15.3 14.0 0.16 11.8 9.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) EPL1 PF10513.4 EME82743.1 - 0.96 9.6 4.2 9.3 6.4 2.9 2.0 1 1 0 1 1 1 0 Enhancer of polycomb-like CH PF00307.26 EME82744.1 - 7.3e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Nucleopor_Nup85 PF07575.8 EME82745.1 - 4.7e-30 104.3 0.5 2.9e-15 55.5 0.0 3.3 3 1 0 3 3 3 2 Nup85 Nucleoporin Transp_cyt_pur PF02133.10 EME82746.1 - 3.4e-68 230.1 22.0 2.8e-54 184.3 8.2 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.14 EME82751.1 - 5.9e-43 146.0 0.0 8.2e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME82751.1 - 1.8e-06 27.4 0.0 2.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME82751.1 - 5.9e-06 26.2 0.3 9.2e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME82751.1 - 0.033 14.6 0.1 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GST_C PF00043.20 EME82752.1 - 4.4e-08 32.9 0.0 7.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME82752.1 - 8.5e-08 32.3 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME82752.1 - 4.7e-06 26.5 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME82752.1 - 1.6e-05 24.9 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME82752.1 - 0.0002 21.7 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME82752.1 - 0.00087 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3431 PF11913.3 EME82753.1 - 6.1e-74 248.2 0.7 6.9e-74 248.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2205 PF10224.4 EME82758.1 - 2e-30 104.1 0.7 2.4e-30 103.9 0.5 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_32 PF13654.1 EME82758.1 - 0.054 12.1 0.4 0.06 12.0 0.3 1.1 1 0 0 1 1 1 0 AAA domain Focal_AT PF03623.8 EME82758.1 - 0.072 12.5 0.1 0.31 10.5 0.1 1.8 1 1 1 2 2 2 0 Focal adhesion targeting region Spectrin PF00435.16 EME82758.1 - 0.074 13.3 0.3 0.095 13.0 0.2 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF972 PF06156.8 EME82758.1 - 0.12 12.7 0.3 0.15 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PEP_mutase PF13714.1 EME82759.1 - 6.9e-47 159.6 0.1 8e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EME82759.1 - 9.7e-22 76.8 0.1 1.4e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EME82759.1 - 0.052 12.6 0.1 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase SCP2 PF02036.12 EME82760.1 - 8.8e-24 83.7 1.3 1e-23 83.5 0.9 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EME82760.1 - 6.9e-08 32.5 0.2 8.9e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Nucleoporin_FG PF13634.1 EME82761.1 - 0.0011 19.2 22.6 0.0011 19.2 15.7 10.6 3 2 7 10 10 10 4 Nucleoporin FG repeat region Ran_BP1 PF00638.13 EME82761.1 - 0.0025 17.8 0.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 RanBP1 domain Totivirus_coat PF05518.6 EME82763.1 - 2 6.1 4.0 2.6 5.7 2.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein ADH_zinc_N PF00107.21 EME82765.1 - 1.3e-31 108.8 0.1 2.4e-31 107.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME82765.1 - 9.4e-09 36.2 0.0 1.8e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME82765.1 - 5.5e-06 26.1 0.0 2.9e-05 23.7 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EME82765.1 - 0.046 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 EME82765.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EME82765.1 - 0.15 11.6 0.6 0.38 10.3 0.3 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ubiquitin PF00240.18 EME82766.1 - 5.4e-19 67.3 0.0 8.6e-19 66.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EME82766.1 - 1.5e-08 34.2 0.0 4.1e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EME82766.1 - 4.1e-08 32.8 0.0 6.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EME82766.1 - 4.9e-06 26.4 0.0 8.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME82766.1 - 4.7e-05 23.4 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EME82766.1 - 0.00082 19.5 0.0 0.0025 18.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 EME82766.1 - 0.11 13.1 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ADH_N PF08240.7 EME82768.1 - 6.1e-27 93.5 0.6 1.4e-26 92.3 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME82768.1 - 4.1e-16 58.6 0.1 6.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EME82768.1 - 0.0066 16.5 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Hydantoinase_A PF01968.13 EME82768.1 - 0.039 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase UDPG_MGDP_dh_N PF03721.9 EME82768.1 - 0.041 13.2 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EME82768.1 - 0.06 13.1 0.2 0.76 9.6 0.2 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GFO_IDH_MocA PF01408.17 EME82769.1 - 6.1e-24 84.8 0.0 9.3e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EME82769.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_16 PF00722.16 EME82771.1 - 1.8e-40 138.2 4.4 3.2e-40 137.3 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EME82771.1 - 0.045 13.7 13.4 0.17 11.9 9.3 2.0 1 0 0 1 1 1 0 Chitin recognition protein Ribosomal_S21e PF01249.13 EME82772.1 - 3.7e-42 142.1 0.0 4.1e-42 142.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e MARVEL PF01284.18 EME82773.1 - 0.00026 20.8 13.3 0.00041 20.1 6.5 2.0 1 1 1 2 2 2 1 Membrane-associating domain Baculo_11_kDa PF06143.6 EME82773.1 - 0.14 11.5 1.3 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF3021 PF11457.3 EME82773.1 - 0.23 11.3 8.9 0.074 12.9 4.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3021) 7TMR-DISM_7TM PF07695.6 EME82773.1 - 0.69 9.5 11.9 0.19 11.3 5.5 1.8 2 0 0 2 2 2 0 7TM diverse intracellular signalling ABC2_membrane_5 PF13346.1 EME82773.1 - 0.98 8.6 13.4 0.26 10.5 6.8 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Ndc1_Nup PF09531.5 EME82774.1 - 0.029 12.8 1.2 0.035 12.5 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SH3_9 PF14604.1 EME82775.1 - 2.2e-14 52.7 0.0 4.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME82775.1 - 6.8e-12 44.5 0.0 1.6e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EME82775.1 - 3.6e-09 36.3 0.0 6.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EME82775.1 - 1.9e-08 34.4 0.0 5.5e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 EME82775.1 - 4e-06 26.2 0.0 9.4e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EME82775.1 - 5.3e-05 23.4 0.0 0.00017 21.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 EME82775.1 - 0.03 14.5 0.1 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EME82775.1 - 0.075 13.1 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.15 EME82777.1 - 2.7e-09 36.3 1.2 4.4e-09 35.7 0.8 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger WD40 PF00400.27 EME82778.1 - 7.2e-19 66.9 9.2 6.4e-08 32.1 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EME82778.1 - 4.8e-06 26.4 0.0 0.098 12.3 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.1 EME82778.1 - 0.0019 17.9 5.8 0.0019 17.9 4.0 2.4 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME82778.1 - 4.8 7.3 10.2 26 5.0 7.1 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger p450 PF00067.17 EME82781.1 - 1.5e-20 73.2 0.0 1.7e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank PF00023.25 EME82782.1 - 0.0012 18.5 0.2 3.2 7.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EME82782.1 - 0.0033 17.5 0.0 1.5 9.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EME82782.1 - 0.0055 17.0 0.0 0.082 13.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME82782.1 - 0.033 14.7 0.0 0.24 11.9 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) FAA_hydrolase PF01557.13 EME82784.1 - 2.4e-57 193.9 0.0 3e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NIL PF09383.5 EME82784.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 NIL domain Pkinase PF00069.20 EME82785.1 - 5.9e-63 212.4 0.0 8.2e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82785.1 - 3.1e-30 105.1 0.0 6.8e-30 104.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82785.1 - 0.00038 19.5 0.0 0.0016 17.4 0.0 2.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EME82785.1 - 0.0021 17.8 0.1 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EME82785.1 - 0.0033 16.5 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.1 EME82785.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 PH domain Pkinase PF00069.20 EME82786.1 - 5.6e-15 55.1 0.1 1.7e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME82786.1 - 2.7e-08 33.2 0.0 8e-08 31.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82786.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Spore_YtfJ PF09579.5 EME82786.1 - 3.8 7.4 5.3 11 5.9 3.7 1.8 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) DEAD PF00270.24 EME82787.1 - 1.4e-43 148.3 0.0 2.1e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME82787.1 - 4.9e-22 77.5 0.2 1.1e-21 76.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME82787.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit F-box-like_2 PF13013.1 EME82788.1 - 0.0068 16.1 0.3 0.096 12.4 0.0 2.6 2 1 0 2 2 2 1 F-box-like domain Fungal_trans_2 PF11951.3 EME82790.1 - 4.2e-07 28.9 0.0 5.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME82790.1 - 3.3e-06 26.8 8.8 4.7e-06 26.3 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C1_2 PF03051.10 EME82792.1 - 3.9e-156 519.9 0.0 4.6e-156 519.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EME82792.1 - 5.6e-07 29.6 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Fungal_trans PF04082.13 EME82793.1 - 1.7e-19 69.7 0.1 3.8e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME82793.1 - 5.3e-09 35.8 11.0 1.2e-08 34.7 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alginate_exp PF13372.1 EME82793.1 - 0.017 13.7 0.1 0.025 13.2 0.1 1.2 1 0 0 1 1 1 0 Alginate export MgrB PF13998.1 EME82796.1 - 0.049 13.4 0.7 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 MgrB protein zf-PHD-like PF15446.1 EME82799.1 - 4.5e-67 224.7 12.7 4.5e-67 224.7 8.8 1.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EME82799.1 - 3.2e-56 190.3 0.0 4.4e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME82799.1 - 1.4e-13 50.5 0.0 3.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EME82799.1 - 3.6e-12 45.7 2.4 1.2e-11 44.0 1.7 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EME82799.1 - 0.00033 20.2 7.1 0.00033 20.2 4.9 3.3 2 2 0 2 2 2 1 PHD-finger Chromo PF00385.19 EME82799.1 - 0.00073 19.1 0.0 0.23 11.1 0.0 3.1 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 EME82799.1 - 0.14 11.5 15.6 0.04 13.2 5.5 3.6 2 1 0 2 2 2 0 PHD-finger SPDY PF03771.11 EME82800.1 - 0.015 14.7 0.1 8 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF317) SpoU_methylase PF00588.14 EME82801.1 - 4.6e-24 84.9 0.0 7.9e-24 84.1 0.0 1.4 1 1 0 1 1 1 1 SpoU rRNA Methylase family DUF504 PF04457.7 EME82802.1 - 4.3e-08 33.1 0.5 9.3e-08 32.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Sugar_tr PF00083.19 EME82803.1 - 4.5e-81 272.7 21.2 5.1e-81 272.5 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82803.1 - 4.2e-15 55.3 28.9 4.2e-15 55.3 20.0 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME82803.1 - 4.2e-06 25.4 23.8 0.00037 19.0 1.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Lactamase_B_2 PF12706.2 EME82804.1 - 6.4e-12 45.4 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME82804.1 - 0.051 13.2 0.1 0.11 12.1 0.1 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Ras PF00071.17 EME82805.1 - 2.6e-16 59.4 0.0 4.5e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EME82805.1 - 8.5e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein NACHT PF05729.7 EME82805.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME82805.1 - 0.027 14.4 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EME82805.1 - 0.056 12.6 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME82805.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hydrolase_like2 PF13246.1 EME82805.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit AAA_22 PF13401.1 EME82805.1 - 0.083 13.0 0.0 0.44 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain IIGP PF05049.8 EME82805.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pribosyl_synth PF14572.1 EME82806.1 - 6.5e-35 120.5 0.3 3.6e-29 101.8 0.1 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EME82806.1 - 8.6e-33 112.5 0.0 2.6e-32 110.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EME82806.1 - 2e-12 46.9 0.0 8.2e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME82806.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase CDC45 PF02724.9 EME82807.1 - 1.6e-185 617.7 0.0 1.9e-185 617.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EME82807.1 - 0.42 8.4 11.4 0.63 7.8 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family MIP PF00230.15 EME82808.1 - 1.8e-46 158.4 8.6 2.1e-46 158.2 6.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 EME82811.1 - 4.9e-28 97.8 49.1 4.9e-28 97.8 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2293 PF10056.4 EME82812.1 - 0.0063 16.4 0.4 0.0093 15.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Selenoprotein_S PF06936.6 EME82812.1 - 0.0076 15.8 3.2 0.0087 15.6 2.2 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) CAF-1_p150 PF11600.3 EME82812.1 - 0.035 13.4 11.0 0.041 13.2 7.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PP_kinase PF02503.12 EME82812.1 - 0.05 13.0 0.5 0.065 12.7 0.4 1.2 1 0 0 1 1 1 0 Polyphosphate kinase middle domain DUF4653 PF15546.1 EME82812.1 - 0.057 12.6 2.1 0.068 12.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) TMEM51 PF15345.1 EME82812.1 - 0.29 10.7 4.4 0.33 10.6 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 RasGAP PF00616.14 EME82813.1 - 9e-44 149.4 0.0 6e-43 146.8 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EME82813.1 - 7.9e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pro_isomerase PF00160.16 EME82816.1 - 1.4e-46 158.4 0.3 2.1e-46 157.9 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EME82816.1 - 3.8e-10 39.2 7.0 2.1e-06 27.2 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EME82816.1 - 1.9e-07 30.4 2.6 0.01 15.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME82816.1 - 3.1e-05 23.3 5.0 0.033 13.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME82816.1 - 0.0014 18.4 1.9 1.1 9.2 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME82816.1 - 0.0031 17.9 0.4 0.8 10.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME82816.1 - 0.0082 15.8 2.3 0.14 11.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME82816.1 - 0.011 16.3 6.1 1.3 9.8 1.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME82816.1 - 0.048 14.1 0.6 6 7.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME82816.1 - 0.22 11.8 5.0 7.6 6.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EME82816.1 - 2.6 7.9 8.3 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Strep_SA_rep PF06696.6 EME82816.1 - 2.7 7.8 7.7 9.1 6.1 1.5 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Trehalase PF01204.13 EME82817.1 - 2.3e-183 610.5 0.0 2.9e-183 610.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EME82817.1 - 5.3e-16 57.6 1.0 8.5e-16 56.9 0.7 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain SH3_1 PF00018.23 EME82818.1 - 9.7e-15 53.6 0.0 1.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME82818.1 - 1.3e-11 43.9 0.0 2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EME82818.1 - 1.2e-08 34.2 0.0 2.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-C4H2 PF10146.4 EME82818.1 - 8.1 6.3 7.6 17 5.3 5.2 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein PI-PLC-X PF00388.14 EME82819.1 - 5.2e-46 155.6 0.0 1.2e-45 154.5 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EME82819.1 - 2e-33 114.8 0.0 3e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EME82819.1 - 0.0074 16.1 1.2 0.045 13.6 0.4 2.6 2 1 0 2 2 2 1 C2 domain Glyco_hydro_31 PF01055.21 EME82820.1 - 3.8e-54 184.1 5.8 4.9e-54 183.8 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME82820.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.8 3 1 0 3 3 3 0 Galactose mutarotase-like Pkinase PF00069.20 EME82821.1 - 7e-61 205.6 0.0 9.5e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82821.1 - 1.1e-36 126.1 0.0 4.1e-35 121.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82821.1 - 1.1e-06 27.8 0.0 0.0035 16.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME82821.1 - 0.0001 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME82821.1 - 0.0017 17.7 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EME82821.1 - 0.0028 16.7 0.1 0.0056 15.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EME82821.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL POM121 PF15229.1 EME82822.1 - 0.022 14.1 2.9 0.026 13.9 2.0 1.0 1 0 0 1 1 1 0 POM121 family DUF4448 PF14610.1 EME82823.1 - 0.0082 15.6 0.0 0.027 13.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.1 EME82823.1 - 0.018 15.1 0.4 0.06 13.5 0.3 1.9 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ctr PF04145.10 EME82823.1 - 0.098 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Ctr copper transporter family E1-E2_ATPase PF00122.15 EME82824.1 - 9e-55 185.2 0.1 9e-55 185.2 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 EME82824.1 - 2.9e-45 152.2 0.2 2.4e-12 46.8 0.4 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EME82824.1 - 5.3e-45 154.4 0.1 1.7e-44 152.8 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME82824.1 - 7.6e-13 49.0 0.0 1.8e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME82824.1 - 0.0018 17.8 0.4 0.0047 16.5 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1639 PF07797.9 EME82824.1 - 0.07 12.5 0.1 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) DUF2554 PF10829.3 EME82826.1 - 0.011 15.7 0.2 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) YjgP_YjgQ PF03739.9 EME82828.1 - 0.023 13.4 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2205 PF10224.4 EME82828.1 - 0.075 12.6 0.4 6.7 6.3 0.1 2.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) adh_short PF00106.20 EME82829.1 - 3e-13 50.0 0.0 7.6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME82829.1 - 0.0012 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EME82829.1 - 0.0013 18.4 0.6 0.0027 17.4 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_16 PF10294.4 EME82830.1 - 0.043 13.2 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Glyco_hydro_31 PF01055.21 EME82831.1 - 2.3e-170 567.2 5.9 2.9e-170 566.8 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4416 PF14385.1 EME82831.1 - 0.053 13.2 0.1 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) GHL15 PF14885.1 EME82831.1 - 2.4 8.4 9.6 0.067 13.4 1.9 2.0 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Cerato-platanin PF07249.7 EME82832.1 - 1.1e-48 164.2 2.8 1.2e-48 163.9 1.9 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EME82832.1 - 0.017 14.7 0.8 0.026 14.1 0.5 1.5 1 1 0 1 1 1 0 Barwin family CbiG_N PF11760.3 EME82833.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Clathrin_H_link PF13838.1 EME82833.1 - 0.08 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Clathrin-H-link Spo0A_C PF08769.6 EME82833.1 - 0.084 12.7 0.2 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Membr_traf_MHD PF10540.4 EME82835.1 - 1.9e-25 89.2 0.0 4.3e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EME82835.1 - 1.1e-15 57.1 0.0 2.8e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EME82835.1 - 0.0072 14.6 1.2 0.03 12.5 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF810) HLH PF00010.21 EME82836.1 - 3.4e-05 23.4 0.0 6.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tenui_NCP PF04876.7 EME82836.1 - 0.064 12.7 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein DSBA PF01323.15 EME82836.1 - 0.086 12.3 0.6 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Fungal_trans PF04082.13 EME82837.1 - 2.8e-18 65.7 1.5 1.1e-17 63.7 0.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME82837.1 - 1.5e-06 28.0 10.9 4.3e-06 26.5 7.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 EME82838.1 - 1.8e-18 67.3 0.0 3e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME82838.1 - 3e-15 55.4 0.4 1.6e-12 46.4 0.1 2.9 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME82838.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME82838.1 - 5.6e-05 22.2 0.0 0.0033 16.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME82838.1 - 5.6e-05 22.9 0.1 0.0015 18.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME82838.1 - 0.0013 18.6 0.0 0.029 14.2 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EME82838.1 - 0.072 13.1 0.0 2.6 8.1 0.0 2.9 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase ETC_C1_NDUFA5 PF04716.9 EME82838.1 - 0.074 12.5 1.1 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 ETC complex I subunit conserved region APP_N PF02177.11 EME82838.1 - 0.098 12.5 0.2 8.3 6.3 0.1 2.6 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding NAD_binding_7 PF13241.1 EME82838.1 - 0.16 12.2 0.1 0.89 9.8 0.0 2.2 3 0 0 3 3 3 0 Putative NAD(P)-binding Abhydrolase_3 PF07859.8 EME82840.1 - 9.9e-27 93.8 0.0 1.2e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EME82840.1 - 6.4e-08 31.6 0.0 7.6e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EME82840.1 - 2.9e-05 23.8 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3237 PF11578.3 EME82841.1 - 1.7e-11 43.6 0.1 2.1e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Sugar_tr PF00083.19 EME82842.1 - 2.1e-74 250.7 31.0 2.4e-74 250.5 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82842.1 - 8.9e-21 73.9 39.7 8.9e-21 73.9 27.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb1_1 PF04997.7 EME82843.1 - 2.2e-110 369.0 0.0 4.4e-110 368.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EME82843.1 - 8.8e-100 333.5 0.2 1.4e-99 332.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EME82843.1 - 2.1e-67 226.2 0.0 4.6e-67 225.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EME82843.1 - 1.2e-56 191.4 3.8 2.3e-56 190.5 2.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EME82843.1 - 2.4e-44 150.8 0.0 4.4e-44 149.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EME82843.1 - 4.6e-41 139.6 1.1 9.4e-41 138.6 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EME82843.1 - 1.5e-32 111.5 0.1 5.8e-32 109.6 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EME82843.1 - 1.2 9.4 56.2 0.36 11.0 6.5 6.7 6 1 0 6 6 6 0 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EME82844.1 - 1.3e-12 47.0 4.9 0.0054 16.5 0.5 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EME82844.1 - 7.1e-05 22.6 0.1 0.71 9.5 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3984 PF13136.1 EME82844.1 - 0.068 12.3 0.7 0.12 11.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Pkinase PF00069.20 EME82845.1 - 1.4e-22 80.0 0.0 8.1e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME82845.1 - 1.3e-13 50.6 0.0 2.9e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME82845.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 EME82846.1 - 6.8e-61 200.1 22.4 3.8e-11 42.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EME82846.1 - 9.5e-05 20.7 5.9 0.21 9.6 0.4 4.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EME82846.1 - 0.026 12.8 0.1 3.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain MRJP PF03022.11 EME82847.1 - 4.9e-14 52.2 0.0 6.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EME82847.1 - 2.8e-07 30.1 0.2 0.0029 17.0 0.1 3.1 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EME82847.1 - 0.0045 16.8 0.1 0.11 12.5 0.0 3.0 3 0 0 3 3 3 1 NHL repeat PD40 PF07676.7 EME82847.1 - 0.11 12.1 0.0 0.48 10.1 0.0 2.1 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Peptidase_M23 PF01551.17 EME82848.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 VWA_3 PF13768.1 EME82850.1 - 4.2e-31 107.7 0.0 7.8e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EME82850.1 - 2.9e-12 46.3 0.0 1.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EME82850.1 - 1e-09 38.3 0.0 7.6e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EME82850.1 - 1.1e-07 32.1 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EME82850.1 - 0.0015 17.9 0.1 0.0041 16.5 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EME82850.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein MPC PF03650.8 EME82851.1 - 0.041 13.8 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0041) MCM_N PF14551.1 EME82851.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain Bul1_N PF04425.7 EME82852.1 - 6.7e-09 34.8 0.2 2.7e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EME82852.1 - 1.8e-05 24.0 0.0 3.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 EME82852.1 - 8.7e-05 22.3 0.0 0.0037 17.1 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 EME82853.1 - 1.5e-16 60.5 0.0 4.2e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Lact-deh-memb PF09330.6 EME82854.1 - 0.097 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Fer4_13 PF13370.1 EME82854.1 - 1.4 9.4 6.4 4.2 7.8 0.2 4.0 3 2 0 3 3 3 0 4Fe-4S single cluster domain TFIIA PF03153.8 EME82855.1 - 1.8e-73 248.6 19.9 2.1e-73 248.4 13.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EME82855.1 - 0.0037 15.5 29.4 0.0045 15.2 20.4 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EME82855.1 - 0.15 10.2 53.3 0.19 9.8 36.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nop14 PF04147.7 EME82859.1 - 8.6 4.1 9.9 12 3.6 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family S_layer_C PF05124.7 EME82860.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 S-layer like family, C-terminal region DUF2462 PF09495.5 EME82862.1 - 3.9e-18 65.9 13.2 3.9e-18 65.9 9.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) RNA_pol_Rpc4 PF05132.9 EME82862.1 - 0.44 10.5 3.8 0.54 10.2 2.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PTRF_SDPR PF15237.1 EME82863.1 - 0.0065 15.9 0.7 0.013 14.8 0.5 1.6 1 0 0 1 1 1 1 PTRF/SDPR family DASH_Spc19 PF08287.6 EME82863.1 - 0.4 10.2 3.8 1.5 8.3 1.1 2.2 2 0 0 2 2 2 0 Spc19 PcfJ PF14284.1 EME82863.1 - 0.5 9.8 3.6 0.31 10.5 0.1 2.1 2 0 0 2 2 2 0 PcfJ-like protein Noc2 PF03715.8 EME82864.1 - 1.1e-115 385.5 0.0 1.8e-115 384.8 0.0 1.3 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.7 EME82864.1 - 0.27 9.1 0.0 0.27 9.1 0.0 3.8 2 2 0 3 3 3 0 Nop14-like family VPS28 PF03997.7 EME82865.1 - 1.5e-55 187.7 0.7 1.8e-55 187.4 0.5 1.1 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EME82865.1 - 0.12 12.2 3.3 2.4 8.0 0.5 2.4 2 0 0 2 2 2 0 Gas vesicle protein G Methyltransf_16 PF10294.4 EME82866.1 - 3.2e-18 65.7 0.0 1.2e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.1 EME82866.1 - 0.005 16.5 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME82866.1 - 0.041 13.9 0.7 0.085 12.8 0.5 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME82866.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DIOX_N PF14226.1 EME82867.1 - 9.3e-34 116.4 0.0 2.4e-32 111.8 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME82867.1 - 2.6e-15 56.5 0.0 6.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily bZIP_1 PF00170.16 EME82869.1 - 3e-05 23.8 9.7 6.2e-05 22.8 1.8 2.2 1 1 1 2 2 2 2 bZIP transcription factor ASD2 PF08687.6 EME82869.1 - 0.0029 16.9 3.8 0.0033 16.7 2.6 1.0 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 bZIP_2 PF07716.10 EME82869.1 - 0.064 13.0 12.5 0.45 10.3 2.9 2.3 1 1 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EME82869.1 - 0.075 12.9 1.5 0.27 11.2 0.4 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 EME82869.1 - 0.13 12.6 2.9 0.11 12.8 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EME82869.1 - 0.49 10.7 5.3 1.1 9.5 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EME82869.1 - 7.9 6.0 7.1 3.9 7.0 1.2 2.2 1 1 1 2 2 2 0 Septum formation initiator Glyco_hydro_1 PF00232.13 EME82870.1 - 1.3e-164 547.7 0.2 1.6e-164 547.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1479 PF07350.7 EME82871.1 - 7.5e-154 512.2 0.0 8.4e-154 512.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EME82871.1 - 0.037 14.0 0.0 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) PKD_channel PF08016.7 EME82871.1 - 0.26 9.6 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel GFA PF04828.9 EME82872.1 - 0.11 12.3 0.1 0.25 11.3 0.1 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Gla PF00594.15 EME82873.1 - 0.084 12.5 0.7 0.2 11.3 0.5 1.6 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain eIF-5_eIF-2B PF01873.12 EME82875.1 - 7.3e-45 151.6 0.1 1.2e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EME82875.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 EME82875.1 - 1.9 8.6 7.2 1.1 9.4 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.7 EME82875.1 - 4.3 6.8 6.1 14 5.1 2.7 2.6 2 1 1 3 3 3 0 HypF finger DUF2201_N PF13203.1 EME82875.1 - 5.3 6.1 14.2 6.2 5.8 9.5 1.4 1 1 0 1 1 1 0 Putative metallopeptidase domain F-box-like PF12937.2 EME82876.1 - 6.7e-06 25.7 0.5 2.5e-05 23.8 0.4 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EME82876.1 - 0.017 14.7 1.3 0.13 11.9 0.9 2.4 1 1 0 1 1 1 0 F-box domain SATase_N PF06426.9 EME82876.1 - 0.093 12.9 1.0 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Glyco_hydro_15 PF00723.16 EME82877.1 - 2.3e-62 211.0 0.6 2.9e-62 210.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_21 PF03370.8 EME82877.1 - 0.015 15.2 0.1 0.059 13.3 0.0 2.1 2 0 0 2 2 2 0 Putative phosphatase regulatory subunit Abhydrolase_6 PF12697.2 EME82878.1 - 5.5e-10 39.5 0.0 9.8e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME82878.1 - 2.4e-06 27.3 0.0 6.9e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME82878.1 - 0.00018 20.8 0.0 0.15 11.2 0.0 2.4 1 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EME82878.1 - 0.092 12.2 0.0 0.4 10.1 0.0 1.6 1 1 0 2 2 2 0 alpha/beta hydrolase fold UTP15_C PF09384.5 EME82881.1 - 2.5e-27 95.3 0.0 4.1e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EME82881.1 - 6e-22 76.6 8.7 8.5e-08 31.7 0.1 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EME82881.1 - 0.099 10.7 1.3 3.8 5.5 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EME82881.1 - 0.27 11.5 3.6 3.9 7.8 0.2 3.4 3 0 0 3 3 3 0 PQQ-like domain zf-DNL PF05180.7 EME82883.1 - 0.18 11.5 4.1 1.9 8.2 0.7 2.5 2 0 0 2 2 2 0 DNL zinc finger Zn_Tnp_IS1595 PF12760.2 EME82883.1 - 0.35 10.7 4.6 1.1 9.0 2.8 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thg1C PF14413.1 EME82885.1 - 1.7e-50 169.7 0.8 2.2e-50 169.3 0.6 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EME82885.1 - 1.1e-42 144.8 0.0 1.7e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase CoA_transf_3 PF02515.12 EME82888.1 - 1.2e-27 96.3 0.0 6.9e-25 87.4 0.0 2.7 2 1 0 2 2 2 2 CoA-transferase family III Phage_AlpA PF05930.7 EME82888.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) DUF1446 PF07287.6 EME82889.1 - 2.3e-124 414.5 0.0 3.2e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) OTU PF02338.14 EME82890.1 - 3.3e-17 63.2 0.0 3.3e-17 63.2 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EME82890.1 - 0.00049 19.5 0.0 0.31 10.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain LacI PF00356.16 EME82890.1 - 0.82 9.3 3.1 17 5.1 0.5 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family NfI_DNAbd_pre-N PF10524.4 EME82890.1 - 1.2 8.8 4.7 0.69 9.5 0.3 2.4 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus SPOUT_MTase PF02590.12 EME82890.1 - 2.4 7.8 8.1 6.1 6.5 1.3 2.3 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Phage_Mu_F PF04233.9 EME82890.1 - 5.5 7.5 9.7 19 5.8 6.7 2.0 1 1 0 1 1 1 0 Phage Mu protein F like protein DUF1768 PF08719.6 EME82891.1 - 5e-15 55.5 0.1 8.8e-15 54.7 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Glyco_trans_2_3 PF13632.1 EME82892.1 - 9.2e-48 162.5 3.6 2.3e-47 161.2 2.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EME82892.1 - 5.6e-09 36.1 0.2 1.3e-07 31.7 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EME82892.1 - 1.3e-05 24.9 0.0 0.0002 21.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EME82892.1 - 0.00015 21.0 0.1 0.00053 19.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 HORMA PF02301.13 EME82894.1 - 1.5e-46 158.5 0.1 1.9e-46 158.1 0.1 1.1 1 0 0 1 1 1 1 HORMA domain TAF PF02969.12 EME82894.1 - 0.0096 15.8 0.3 0.02 14.8 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Spherulin4 PF12138.3 EME82894.1 - 0.078 12.3 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 FlxA PF14282.1 EME82894.1 - 0.12 12.3 0.4 0.12 12.3 0.3 3.0 3 0 0 3 3 3 0 FlxA-like protein DUF3445 PF11927.3 EME82894.1 - 0.15 11.4 0.5 1.6 8.0 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3445) RICH PF05062.7 EME82894.1 - 2.1 8.5 9.1 0.25 11.4 0.3 2.9 3 0 0 3 3 3 0 RICH domain GTP_EFTU PF00009.22 EME82895.1 - 6e-48 162.7 0.0 1.1e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EME82895.1 - 7e-37 125.6 4.7 1.2e-36 124.8 3.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EME82895.1 - 4.7e-19 68.0 0.0 9.4e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EME82895.1 - 1.1e-05 24.9 0.0 3.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 EME82895.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EME82895.1 - 5.6e-05 23.0 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EME82895.1 - 0.0028 17.7 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EME82895.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fork_head PF00250.13 EME82896.1 - 6.4e-15 54.9 0.2 7.3e-15 54.7 0.1 1.0 1 0 0 1 1 1 1 Fork head domain Interferon PF00143.14 EME82896.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain Proteasome PF00227.21 EME82896.1 - 0.14 11.4 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Proteasome subunit 2OG-FeII_Oxy_3 PF13640.1 EME82897.1 - 1.5e-11 44.6 0.0 3.6e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EME82897.1 - 1.9e-06 27.3 0.0 4.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EME82897.1 - 8e-05 22.8 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAT1 PF09770.4 EME82899.1 - 0.51 8.5 7.4 0.63 8.2 5.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_N_3 PF13417.1 EME82900.1 - 1.4e-16 60.4 0.0 2.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME82900.1 - 7.6e-12 45.0 0.0 1.8e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME82900.1 - 4.8e-07 29.8 0.1 1.1e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EME82900.1 - 7e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 EME82900.1 - 0.00043 20.1 0.1 0.00084 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Reticulon PF02453.12 EME82901.1 - 2.1e-34 118.6 4.7 3.1e-34 118.0 3.3 1.3 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.1 EME82901.1 - 1.8 8.4 8.8 0.13 12.1 1.3 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Aldolase_II PF00596.16 EME82903.1 - 4.5e-47 160.0 0.0 5.6e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DNA_topoisoIV PF00521.15 EME82904.1 - 8.9e-125 416.8 0.3 2.3e-124 415.5 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EME82904.1 - 6.5e-35 119.8 4.4 6.5e-35 119.8 3.1 2.1 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EME82904.1 - 1.9e-14 53.4 0.0 7.1e-14 51.5 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EME82904.1 - 1.9e-10 40.4 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C2H2_jaz PF12171.3 EME82905.1 - 1.8e-09 37.4 0.4 2.9e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME82905.1 - 3.4e-07 30.2 0.5 6.2e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EME82905.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-U1 PF06220.7 EME82905.1 - 0.076 12.5 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.2 EME82905.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Histidinol_dh PF00815.15 EME82905.1 - 0.18 10.4 1.2 3.8 6.0 0.0 2.0 2 0 0 2 2 2 0 Histidinol dehydrogenase DUF1764 PF08576.5 EME82905.1 - 5.5 7.8 11.6 4.8 8.0 4.8 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FDF PF09532.5 EME82905.1 - 5.8 7.5 11.0 20 5.7 4.0 2.2 2 0 0 2 2 2 0 FDF domain RNase_H2-Ydr279 PF09468.5 EME82905.1 - 7.1 5.7 9.2 0.29 10.2 2.5 1.5 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Adeno_VII PF03228.9 EME82905.1 - 9.2 6.8 19.9 2.6 8.6 6.0 2.1 2 0 0 2 2 2 0 Adenoviral core protein VII Sugar_tr PF00083.19 EME82906.1 - 3.7e-76 256.5 28.0 4.3e-76 256.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82906.1 - 6.1e-18 64.6 28.8 6.1e-18 64.6 20.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily GST_N PF02798.15 EME82908.1 - 8.9e-13 48.2 0.0 1.4e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EME82908.1 - 4.6e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME82908.1 - 5e-11 42.3 0.2 9.2e-11 41.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME82908.1 - 5.4e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME82908.1 - 2e-09 37.2 0.0 4.4e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME82908.1 - 1.4e-07 31.9 0.1 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ECR1_N PF14382.1 EME82909.1 - 5e-09 35.2 0.0 6.7e-08 31.6 0.0 2.3 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EME82909.1 - 0.034 14.1 0.1 0.53 10.2 0.1 2.5 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 MFS_1 PF07690.11 EME82910.1 - 8.3e-26 90.5 31.9 8.3e-26 90.5 22.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 EME82910.1 - 6.1 5.9 12.9 1.4 8.0 1.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1275) PHD PF00628.24 EME82911.1 - 0.0014 18.2 11.9 0.0014 18.2 8.2 3.1 4 0 0 4 4 4 1 PHD-finger 2H-phosphodiest PF08975.5 EME82913.1 - 7e-14 51.6 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.1 EME82913.1 - 5.1e-07 29.5 0.1 1.7e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily HVSL PF09749.4 EME82913.1 - 0.0071 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein Sugar_tr PF00083.19 EME82914.1 - 5e-74 249.5 22.4 5.8e-74 249.2 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME82914.1 - 3e-14 52.4 31.6 3.4e-14 52.3 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME82914.1 - 0.00013 20.5 22.1 0.0022 16.4 0.7 3.2 2 1 0 3 3 3 3 MFS/sugar transport protein Inositol_P PF00459.20 EME82916.1 - 2.7e-59 200.7 0.0 3.4e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF4131 PF13567.1 EME82918.1 - 0.9 8.9 4.4 1.6 8.1 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Abhydrolase_6 PF12697.2 EME82921.1 - 3.2e-24 86.1 0.0 3.7e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME82921.1 - 3.4e-15 56.2 0.0 3.1e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME82921.1 - 4e-10 39.6 0.0 6.8e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME82921.1 - 1.4e-08 34.4 0.0 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Esterase PF00756.15 EME82921.1 - 0.00022 20.7 0.0 0.00045 19.7 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Homeobox_KN PF05920.6 EME82922.1 - 7.9e-15 54.2 0.5 2.1e-14 52.9 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 EME82922.1 - 9.4e-07 28.5 0.1 2.8e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Homeobox PF00046.24 EME82922.1 - 1e-05 25.0 0.2 2.9e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 EME82922.1 - 0.0031 17.7 27.5 0.026 14.8 1.7 4.8 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME82922.1 - 0.0045 17.2 1.8 0.0045 17.2 1.2 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME82922.1 - 0.015 15.5 8.1 1 9.7 0.5 3.8 3 1 0 3 3 3 0 Zinc-finger double domain HA PF03457.9 EME82922.1 - 0.017 15.2 3.9 0.019 15.0 0.2 2.9 3 0 0 3 3 3 0 Helicase associated domain zf-C2H2_2 PF12756.2 EME82922.1 - 0.061 13.4 9.9 20 5.3 0.0 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) BIR PF00653.16 EME82922.1 - 0.91 9.9 7.0 5.6 7.4 0.0 3.3 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain zf-CHCC PF10276.4 EME82922.1 - 9.7 6.1 7.6 2.8 7.8 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain 5_nucleotid_C PF02872.13 EME82924.1 - 4.5e-40 137.1 0.0 1.3e-39 135.7 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EME82924.1 - 7.6e-08 31.9 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3905 PF13045.1 EME82924.1 - 0.082 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) His_Phos_1 PF00300.17 EME82925.1 - 1.4e-08 34.9 0.1 6.5e-06 26.3 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF619 PF04768.8 EME82926.1 - 3.5e-51 173.0 0.0 6.1e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AMP-binding PF00501.23 EME82927.1 - 2.5e-52 177.6 0.0 3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M20 PF01546.23 EME82928.1 - 2.3e-22 79.4 4.5 3.9e-22 78.6 3.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME82928.1 - 8.3e-17 60.9 0.8 1.6e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EME82928.1 - 0.0004 20.1 0.1 0.0015 18.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.9 EME82928.1 - 0.025 13.3 0.1 0.34 9.6 0.0 2.2 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase Aldo_ket_red PF00248.16 EME82929.1 - 4.4e-60 202.9 0.0 5.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GST_C PF00043.20 EME82930.1 - 2.2e-09 37.1 0.0 4.5e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME82930.1 - 9.9e-05 22.4 0.0 0.00026 21.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME82930.1 - 0.00057 20.3 0.0 0.0012 19.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME82930.1 - 0.011 15.6 0.0 0.049 13.6 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME82930.1 - 0.057 13.3 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME82930.1 - 0.07 13.3 0.1 0.46 10.7 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EME82931.1 - 1.8e-36 125.6 0.0 4.3e-36 124.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.8 EME82932.1 - 9e-17 61.5 10.1 9e-17 61.5 7.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MBOAT_2 PF13813.1 EME82932.1 - 0.048 13.7 4.3 0.062 13.3 1.1 2.4 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family RQC PF09382.5 EME82932.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 RQC domain p450 PF00067.17 EME82933.1 - 1.4e-45 155.6 0.0 3.1e-45 154.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MipZ PF09140.6 EME82933.1 - 0.061 12.3 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ TPP_enzyme_N PF02776.13 EME82935.1 - 1.7e-56 190.4 0.0 4.9e-56 188.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME82935.1 - 3.8e-37 127.2 0.1 7.6e-36 122.9 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME82935.1 - 1.1e-33 115.9 0.1 2.2e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain tRNA-synt_2 PF00152.15 EME82937.1 - 2.6e-72 243.4 0.0 3.2e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME82937.1 - 5.3e-08 32.6 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME82937.1 - 0.0001 21.6 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) RPA_interact_C PF14768.1 EME82939.1 - 0.038 14.3 0.1 0.2 12.1 0.0 2.2 2 1 0 2 2 2 0 Replication protein A interacting C-terminal DUF1168 PF06658.7 EME82940.1 - 1.5e-41 141.2 11.7 2.1e-41 140.7 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF834 PF05754.9 EME82940.1 - 0.15 11.8 4.9 0.18 11.6 1.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF834) Mnd1 PF03962.10 EME82940.1 - 0.61 9.7 9.5 0.96 9.0 6.6 1.2 1 0 0 1 1 1 0 Mnd1 family His_Phos_1 PF00300.17 EME82941.1 - 4.4e-33 114.6 0.0 5.7e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EME82941.1 - 6.4e-07 29.0 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SUR7 PF06687.7 EME82943.1 - 3.2e-16 59.5 7.1 3.2e-16 59.5 4.9 1.7 1 1 1 2 2 2 1 SUR7/PalI family Claudin_2 PF13903.1 EME82943.1 - 0.00034 20.3 5.4 0.00034 20.3 3.7 2.3 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Tmemb_40 PF10160.4 EME82943.1 - 0.0013 17.9 1.2 0.0024 17.1 0.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein Claudin_3 PF06653.6 EME82943.1 - 0.013 15.2 0.3 0.013 15.2 0.2 2.2 2 1 0 2 2 2 0 Tight junction protein, Claudin-like DUF2269 PF10027.4 EME82943.1 - 0.036 13.8 10.7 1.4 8.7 7.4 2.8 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) 7TM_GPCR_Srv PF10323.4 EME82943.1 - 0.042 12.9 0.1 0.042 12.9 0.1 1.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv TMEM51 PF15345.1 EME82943.1 - 0.044 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 7tm_1 PF00001.16 EME82943.1 - 0.063 12.4 0.1 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) TMEM52 PF14979.1 EME82943.1 - 0.19 11.6 1.1 1 9.2 0.0 2.4 3 0 0 3 3 3 0 Transmembrane 52 K1 PF02960.9 EME82943.1 - 0.24 11.4 1.4 0.25 11.4 0.1 1.6 2 0 0 2 2 2 0 K1 glycoprotein DUF4131 PF13567.1 EME82943.1 - 0.98 8.7 6.5 0.28 10.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EphA2_TM PF14575.1 EME82943.1 - 1.3 9.5 6.4 5.9 7.3 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain zf-DHHC PF01529.15 EME82943.1 - 3.6 6.9 8.1 2.5 7.4 0.9 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase FA_desaturase PF00487.19 EME82943.1 - 5.3 6.3 9.9 0.079 12.3 1.6 1.8 2 1 0 2 2 2 0 Fatty acid desaturase 2OG-FeII_Oxy_3 PF13640.1 EME82944.1 - 7e-08 32.9 0.1 2.7e-07 31.0 0.1 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EME82944.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EME82945.1 - 2.8e-47 161.2 0.1 4.5e-46 157.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 PPP4R2 PF09184.6 EME82948.1 - 4.2e-07 29.8 0.1 4.2e-07 29.8 0.1 3.1 3 1 0 3 3 3 1 PPP4R2 Response_reg PF00072.19 EME82950.1 - 3.8e-26 91.2 0.2 6.8e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EME82950.1 - 1e-25 89.6 0.0 3.2e-25 88.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME82950.1 - 1.3e-13 50.7 0.0 4.2e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EME82950.1 - 0.0017 18.5 5.8 0.81 9.9 0.0 3.8 3 0 0 3 3 3 2 HAMP domain Ras PF00071.17 EME82952.1 - 7.3e-49 165.2 0.0 9.1e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME82952.1 - 1.9e-14 54.1 0.0 4.1e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME82952.1 - 1.7e-10 40.3 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EME82952.1 - 0.00051 20.1 0.1 0.0025 17.9 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EME82952.1 - 0.0013 17.9 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EME82952.1 - 0.021 14.1 0.1 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EME82952.1 - 0.038 12.6 2.4 0.4 9.3 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EME82952.1 - 0.062 13.4 0.2 0.17 11.9 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EME82952.1 - 0.079 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EME82952.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ubiquitin PF00240.18 EME82953.1 - 2.7e-14 52.3 0.2 5.5e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME82953.1 - 1.3e-07 31.2 0.1 2.4e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RF-1 PF00472.15 EME82954.1 - 2.6e-35 120.6 3.5 6.4e-34 116.1 1.8 2.6 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 EME82954.1 - 5.7e-28 96.9 0.0 2.2e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 PCRF domain NAD_binding_6 PF08030.7 EME82955.1 - 1.1e-20 74.0 0.0 1.7e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME82955.1 - 2.6e-19 69.5 5.9 2.6e-19 69.5 4.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME82955.1 - 6.3e-13 48.5 0.1 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EME82955.1 - 2.1e-05 25.0 0.0 0.013 16.0 0.0 2.6 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain Rad51 PF08423.6 EME82956.1 - 0.00029 19.8 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 Rad51 Mitochondr_Som1 PF11093.3 EME82957.1 - 4.5e-16 58.4 0.2 5e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TAF8_C PF10406.4 EME82958.1 - 6.7e-17 61.2 0.2 1.7e-16 59.9 0.2 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EME82958.1 - 1.3e-08 34.4 0.8 2.1e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated Adap_comp_sub PF00928.16 EME82959.1 - 4.4e-54 183.3 0.0 7.1e-54 182.6 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME82959.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain PALP PF00291.20 EME82960.1 - 2.8e-70 236.9 0.2 3.9e-70 236.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SKG6 PF08693.5 EME82961.1 - 0.018 14.3 0.6 0.018 14.3 0.4 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF1517 PF07466.6 EME82961.1 - 0.22 10.4 4.1 0.27 10.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF533 PF04391.7 EME82961.1 - 3.5 6.9 5.0 5.1 6.4 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) MRP-L20 PF12824.2 EME82962.1 - 5.8e-45 153.2 8.6 8.1e-45 152.7 6.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF4316 PF14195.1 EME82962.1 - 0.044 13.8 0.1 0.14 12.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4316) HTH_32 PF13565.1 EME82962.1 - 0.37 11.6 3.3 0.19 12.5 0.3 2.1 2 1 0 2 2 2 0 Homeodomain-like domain VIT1 PF01988.14 EME82964.1 - 8.4e-63 211.6 3.8 9.6e-63 211.5 2.6 1.0 1 0 0 1 1 1 1 VIT family PDGLE PF13190.1 EME82964.1 - 0.047 13.3 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 PDGLE domain ARF7EP_C PF14949.1 EME82964.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 ARF7 effector protein C-terminus FAST_2 PF08368.7 EME82964.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 DUF4341 PF14241.1 EME82964.1 - 0.95 9.2 7.6 3.3 7.4 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4341) Podoplanin PF05808.6 EME82968.1 - 3.2 7.2 7.7 26 4.3 0.0 2.1 2 0 0 2 2 2 0 Podoplanin Lebercilin PF15619.1 EME82969.1 - 0.014 14.7 32.3 0.053 12.9 18.3 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 EME82969.1 - 0.29 10.7 43.2 0.068 12.7 11.3 3.4 2 1 0 3 3 3 0 IncA protein NPV_P10 PF05531.7 EME82969.1 - 0.72 10.1 13.1 0.077 13.2 1.0 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.6 EME82969.1 - 1.2 8.5 20.6 3.9 6.8 0.7 3.8 2 1 1 3 3 3 0 Phage minor structural protein GP20 DivIVA PF05103.8 EME82969.1 - 2.1 8.3 34.1 0.15 12.1 0.2 4.1 3 1 0 3 3 3 0 DivIVA protein GAS PF13851.1 EME82969.1 - 4.2 6.5 31.9 2.8 7.0 0.5 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EME82969.1 - 4.5 7.1 41.5 0.35 10.7 15.9 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Iso_dh PF00180.15 EME82970.1 - 1.2e-72 244.7 0.0 1.4e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ECH PF00378.15 EME82971.1 - 2.7e-38 131.4 0.0 3.5e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Amidohydro_2 PF04909.9 EME82972.1 - 6.6e-47 160.3 0.0 7.8e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase BTB PF00651.26 EME82973.1 - 8.5e-07 28.9 0.0 3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.22 EME82974.1 - 7.4e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain Ribosomal_L18ae PF01775.12 EME82975.1 - 3e-60 201.5 0.5 3.8e-60 201.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Transp_cyt_pur PF02133.10 EME82976.1 - 1.8e-100 336.5 32.6 2.1e-100 336.3 22.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 EME82977.1 - 2.6e-80 269.6 0.1 5.7e-79 265.2 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EME82977.1 - 2.1e-46 158.3 6.8 1.4e-41 142.5 1.0 2.7 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EME82977.1 - 3.2e-18 65.8 0.3 1.1e-16 60.8 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EME82977.1 - 0.018 14.0 0.0 2.5 6.9 0.1 3.0 3 0 0 3 3 3 0 StbA protein MutL PF13941.1 EME82977.1 - 0.073 11.3 4.1 0.92 7.7 0.1 3.0 4 0 0 4 4 4 0 MutL protein Bap31 PF05529.7 EME82978.1 - 1.2e-63 214.0 1.8 1.4e-63 213.8 1.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Spc7 PF08317.6 EME82978.1 - 0.0077 14.9 0.5 0.011 14.4 0.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DivIC PF04977.10 EME82978.1 - 0.008 15.6 7.7 0.064 12.7 0.6 3.7 3 1 1 4 4 4 1 Septum formation initiator TMF_TATA_bd PF12325.3 EME82978.1 - 0.01 15.5 0.6 0.019 14.6 0.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 EME82978.1 - 0.012 15.5 4.5 0.39 10.7 1.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF4349 PF14257.1 EME82978.1 - 0.083 12.1 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF641 PF04859.7 EME82978.1 - 0.093 12.4 0.5 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EME82978.1 - 0.13 12.0 5.4 0.096 12.5 1.7 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Dus PF01207.12 EME82979.1 - 1.6e-36 125.7 0.0 4.1e-26 91.5 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EME82979.1 - 2.4 7.9 5.8 2.9 7.6 0.2 3.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 EME82980.1 - 0.00043 20.4 9.7 0.051 13.9 0.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME82980.1 - 0.0027 17.7 7.6 0.1 12.7 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EME82980.1 - 0.0037 17.5 13.8 0.049 13.9 0.9 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME82980.1 - 0.0043 17.2 11.6 0.01 16.1 0.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EME82980.1 - 4.9 7.2 7.6 0.49 10.3 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Amidase PF01425.16 EME82982.1 - 1e-61 209.1 0.0 1.5e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Peptidase_S7 PF00949.16 EME82982.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease WD40 PF00400.27 EME82985.1 - 2.8e-12 46.0 2.0 9.5e-05 22.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat SnoaL_4 PF13577.1 EME82987.1 - 0.013 15.3 0.0 0.061 13.2 0.0 1.9 1 1 0 1 1 1 0 SnoaL-like domain Lumazine_bd_2 PF12893.2 EME82987.1 - 0.015 15.8 0.0 0.036 14.5 0.0 1.7 1 1 1 2 2 2 0 Putative lumazine-binding DUF4440 PF14534.1 EME82987.1 - 0.095 12.9 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Sedlin_N PF04628.8 EME82987.1 - 0.1 12.4 0.1 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region Surface_Ag_2 PF01617.12 EME82988.1 - 0.019 14.1 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Surface antigen Acetyltransf_1 PF00583.19 EME82989.1 - 0.00072 19.5 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME82989.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DUF500 PF04366.7 EME82990.1 - 2.6e-48 162.6 0.1 4.4e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF2422 PF10337.4 EME82990.1 - 0.011 14.4 0.4 0.017 13.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) LAM_C PF12544.3 EME82991.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 EME82991.1 - 0.0028 17.8 0.0 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EME82991.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain Pro_isomerase PF00160.16 EME82992.1 - 1.1e-34 119.8 0.0 1.7e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EME82992.1 - 1.3e-16 59.9 0.0 2.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME82992.1 - 9.6e-12 44.7 0.0 2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME82992.1 - 1.5e-10 40.7 0.1 4.7e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EME82993.1 - 0.0011 18.8 2.8 0.0023 17.7 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Histidinol_dh PF00815.15 EME82995.1 - 3.2e-174 579.3 6.1 3.2e-174 579.3 4.2 1.4 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EME82995.1 - 4.9e-24 83.7 0.8 9.2e-24 82.8 0.6 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EME82995.1 - 1.7e-11 44.2 0.2 5.4e-11 42.6 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EME82995.1 - 0.069 13.1 0.6 0.18 11.7 0.4 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Abhydrolase_5 PF12695.2 EME82996.1 - 2.9e-09 36.8 0.0 5.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME82996.1 - 0.00029 20.8 0.6 0.0011 18.9 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EME82996.1 - 0.2 10.8 1.2 5.4 6.1 0.9 2.3 2 1 0 2 2 2 0 Secretory lipase SAD_SRA PF02182.12 EME82997.1 - 1.1e-20 73.4 0.0 2.3e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain Aminotran_5 PF00266.14 EME82998.1 - 4.3e-58 196.8 0.0 5.3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EME82998.1 - 0.00054 18.3 0.0 0.0017 16.6 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme ORC4_C PF14629.1 EME82998.1 - 0.063 12.6 0.1 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus NmrA PF05368.8 EME82999.1 - 3.6e-22 78.7 0.0 4.6e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EME82999.1 - 0.0028 16.7 0.1 0.0051 15.8 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EME82999.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DnaJ PF00226.26 EME83000.1 - 3.9e-20 71.3 0.7 7.1e-20 70.5 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Redoxin PF08534.5 EME83001.1 - 7.2e-10 38.5 0.0 0.00014 21.4 0.0 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EME83001.1 - 0.052 13.2 0.0 1.1 8.9 0.0 2.2 1 1 0 1 1 1 0 AhpC/TSA family Acetyltransf_2 PF00797.12 EME83004.1 - 9.8e-31 107.1 0.0 4.4e-30 105.0 0.0 2.0 1 1 0 1 1 1 1 N-acetyltransferase Glyco_hydro_76 PF03663.9 EME83008.1 - 1.9e-105 353.2 9.2 2.7e-105 352.7 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TPR_11 PF13414.1 EME83009.1 - 5.4e-53 176.5 40.8 1.9e-13 49.8 0.6 7.0 3 2 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 EME83009.1 - 1.7e-40 134.9 27.8 1.6e-05 24.2 0.0 11.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EME83009.1 - 1.2e-37 124.7 27.1 0.00038 20.1 0.2 11.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EME83009.1 - 5.7e-26 90.5 24.4 1.7e-05 25.3 0.1 7.5 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EME83009.1 - 1.7e-24 83.9 7.9 0.00015 21.6 0.0 8.9 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EME83009.1 - 8.3e-23 80.1 24.8 9.6e-07 28.6 0.1 7.4 2 2 7 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EME83009.1 - 5.4e-13 47.6 19.9 0.054 13.3 0.1 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EME83009.1 - 7.7e-13 48.0 14.0 8.9e-07 28.6 0.1 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME83009.1 - 1.8e-12 46.7 16.5 0.039 14.5 0.2 9.5 5 2 5 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME83009.1 - 4.4e-11 41.7 29.2 0.11 12.3 0.0 9.8 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME83009.1 - 1.2e-09 38.4 24.2 2.4e-05 24.5 0.2 7.2 5 3 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EME83009.1 - 5.4e-07 29.6 18.9 0.0084 16.2 0.1 5.6 2 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EME83009.1 - 0.00078 19.2 18.3 0.096 12.6 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME83009.1 - 0.0039 17.5 27.1 3 8.4 0.0 9.7 11 0 0 11 11 10 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EME83009.1 - 0.025 13.8 14.7 0.66 9.2 0.1 5.5 5 0 0 5 5 5 0 SHNi-TPR HemY_N PF07219.8 EME83009.1 - 0.034 13.7 0.1 18 4.9 0.0 4.0 4 0 0 4 4 4 0 HemY protein N-terminus Sel1 PF08238.7 EME83009.1 - 0.053 14.1 7.5 1.4 9.6 0.1 4.7 4 0 0 4 4 4 0 Sel1 repeat TPR_20 PF14561.1 EME83009.1 - 0.084 12.9 15.3 4.1 7.5 0.2 6.2 5 2 2 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.2 EME83009.1 - 0.2 11.4 10.4 5.4 6.8 0.0 5.0 5 1 0 5 5 4 0 Domain of Unknown Function (DUF3856) Aminotran_4 PF01063.14 EME83010.1 - 2.3e-23 82.8 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV SNF2_N PF00176.18 EME83013.1 - 1.4e-68 230.8 1.0 2.4e-68 230.1 0.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME83013.1 - 4.9e-10 39.1 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EME83013.1 - 3.4e-09 36.2 3.2 6.7e-09 35.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME83013.1 - 1.5e-07 31.2 4.9 3.3e-07 30.2 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME83013.1 - 1.2e-06 28.0 4.6 2.8e-06 26.8 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME83013.1 - 8.7e-06 25.4 4.1 1.7e-05 24.5 2.9 1.5 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EME83013.1 - 3.2e-05 23.5 0.1 0.00031 20.2 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EME83013.1 - 0.00025 20.7 1.2 0.00075 19.1 0.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EME83013.1 - 0.00056 19.5 4.3 0.0015 18.2 3.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME83013.1 - 0.00084 19.1 5.7 0.0021 17.9 4.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EME83013.1 - 0.002 17.6 6.8 0.012 15.1 5.0 2.2 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain SPT6_acidic PF14632.1 EME83013.1 - 0.0057 16.7 26.9 0.0057 16.7 18.7 4.0 4 1 0 4 4 2 1 Acidic N-terminal SPT6 zf-MIZ PF02891.15 EME83013.1 - 0.48 9.9 4.2 1.2 8.6 2.9 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 EME83013.1 - 2.1 8.2 6.9 6.7 6.6 4.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Clr5 PF14420.1 EME83014.1 - 4.6e-09 36.0 0.4 2.4e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Clr5 domain DUF4170 PF13773.1 EME83015.1 - 0.1 12.5 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) adh_short PF00106.20 EME83016.1 - 8.7e-26 90.8 2.2 1.4e-25 90.1 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME83016.1 - 1e-09 38.5 0.0 1.5e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME83016.1 - 2e-07 30.8 1.7 4.5e-07 29.7 1.2 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME83016.1 - 0.044 13.7 0.3 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding SWIB PF02201.13 EME83018.1 - 1.5e-14 53.3 0.0 3.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain EAF PF09816.4 EME83020.1 - 5.3e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor BPL_C PF02237.12 EME83020.1 - 0.12 12.0 0.0 3.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain MFS_1 PF07690.11 EME83025.1 - 5e-22 78.1 39.9 5e-22 78.1 27.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 EME83025.1 - 0.66 9.2 15.8 0.57 9.4 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) DUF1218 PF06749.7 EME83025.1 - 8.7 6.8 11.4 0.32 11.4 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Sigma70_ner PF04546.8 EME83026.1 - 0.24 10.9 1.8 0.29 10.7 1.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3245 PF11595.3 EME83026.1 - 2.1 8.6 5.5 1.3 9.3 2.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Voldacs PF03517.8 EME83026.1 - 4.1 7.2 7.3 5.3 6.8 5.0 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling UCR_hinge PF02320.11 EME83028.1 - 0.038 13.9 1.1 0.042 13.7 0.8 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein SCRL PF06876.7 EME83028.1 - 0.17 11.8 1.2 0.22 11.4 0.9 1.1 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein CHCH PF06747.8 EME83028.1 - 0.6 10.1 2.7 1.4 8.8 1.9 1.8 1 1 1 2 2 2 0 CHCH domain Toxin_3 PF00537.13 EME83028.1 - 0.66 9.8 6.7 1.4 8.8 0.5 2.1 1 1 1 2 2 2 0 Scorpion toxin-like domain Sfi1 PF08457.5 EME83029.1 - 7.9e-84 282.0 86.3 1.2e-82 278.1 52.6 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Fungal_trans PF04082.13 EME83030.1 - 4.4e-05 22.4 0.0 8.7e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_30 PF05430.6 EME83030.1 - 0.16 11.6 0.3 0.63 9.7 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase DUF4596 PF15363.1 EME83030.1 - 0.77 9.7 3.6 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) tRNA-synt_1b PF00579.20 EME83032.1 - 1.7e-21 76.6 0.0 4.3e-14 52.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) PRELI PF04707.9 EME83033.1 - 9.4e-22 77.2 0.0 3.1e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Maf PF02545.9 EME83034.1 - 1.4e-47 161.3 0.0 1.7e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF1689 PF07954.6 EME83034.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) ADH_zinc_N PF00107.21 EME83035.1 - 2.7e-18 65.7 0.0 4.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME83035.1 - 1.9e-05 25.5 0.0 3.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EME83036.1 - 2.2e-16 59.8 0.0 3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME83036.1 - 1.7e-09 37.0 0.1 4e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME83036.1 - 3.8e-06 27.0 0.0 8.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME83036.1 - 0.00015 21.5 0.3 0.0024 17.6 0.2 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME83036.1 - 0.00029 20.7 0.3 0.0015 18.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EME83036.1 - 0.0029 16.2 0.3 0.16 10.5 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 EME83036.1 - 0.015 14.1 0.0 0.033 13.0 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 EME83036.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EME83036.1 - 0.025 14.4 0.0 0.069 13.0 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME83036.1 - 0.074 11.5 0.0 0.3 9.5 0.0 1.8 1 1 0 1 1 1 0 HI0933-like protein RE_CfrBI PF09516.5 EME83037.1 - 0.041 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease Cu_amine_oxid PF01179.15 EME83039.1 - 3.3e-96 322.5 0.4 4.4e-96 322.1 0.3 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EME83039.1 - 1.3e-13 50.5 0.0 3.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Prok-E2_A PF14457.1 EME83039.1 - 0.14 11.6 0.1 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family A OPT PF03169.10 EME83040.1 - 1.9e-145 485.8 14.9 2.4e-145 485.4 10.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein zf-C2H2_2 PF12756.2 EME83041.1 - 0.00011 22.2 0.1 0.00016 21.7 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) COesterase PF00135.23 EME83043.1 - 3.2e-34 118.5 0.0 3.9e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family UQ_con PF00179.21 EME83044.1 - 2.5e-45 153.3 0.0 2.9e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME83044.1 - 0.0034 17.2 0.3 0.0052 16.6 0.2 1.6 1 1 0 1 1 1 1 RWD domain Peptidase_C13 PF01650.13 EME83047.1 - 4.2e-39 134.3 0.0 6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family HET PF06985.6 EME83049.1 - 6.6e-30 104.0 1.0 8.8e-30 103.6 0.7 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PK PF00224.16 EME83049.1 - 0.16 10.5 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain XFP_N PF09364.5 EME83052.1 - 1.7e-174 579.8 0.0 2.8e-174 579.1 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EME83052.1 - 2.3e-81 272.1 0.0 3.4e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EME83052.1 - 5.4e-71 237.8 0.0 1.2e-70 236.7 0.0 1.6 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TRI12 PF06609.8 EME83053.1 - 5.7e-66 222.9 24.1 7.6e-66 222.5 16.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME83053.1 - 1.5e-19 69.9 57.9 6.3e-18 64.5 38.4 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME83053.1 - 5.5e-08 31.8 12.3 5.5e-08 31.8 8.5 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter Arylsulfotran_2 PF14269.1 EME83054.1 - 9.5e-54 182.5 3.4 1.7e-53 181.7 2.4 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 EME83054.1 - 1.5e-19 69.9 4.5 1.5e-19 69.9 3.1 3.6 3 1 1 4 4 4 2 Major Facilitator Superfamily Arylsulfotrans PF05935.6 EME83054.1 - 6.7e-17 61.1 5.4 5.2e-16 58.2 3.8 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_3 PF13469.1 EME83055.1 - 1.3e-05 26.2 0.1 1.9e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF1572 PF07609.6 EME83055.1 - 0.084 12.4 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) CN_hydrolase PF00795.17 EME83056.1 - 5.3e-28 97.6 0.0 7e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_4 PF13147.1 EME83057.1 - 5.9e-25 88.8 0.2 2.3e-24 86.9 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EME83057.1 - 1.8e-17 64.0 0.1 1e-16 61.5 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EME83057.1 - 1.1e-13 50.7 1.0 1.1e-13 50.7 0.7 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EME83057.1 - 1.9e-11 43.8 0.1 1.2e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Na_H_Exchanger PF00999.16 EME83058.1 - 5.5e-31 107.4 36.6 2.4e-26 92.1 14.4 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family FA_desaturase PF00487.19 EME83058.1 - 0.35 10.2 0.0 0.35 10.2 0.0 2.4 3 0 0 3 3 3 0 Fatty acid desaturase PseudoU_synth_1 PF01416.15 EME83059.1 - 2.9e-28 98.3 0.0 7.6e-20 71.2 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase PIG-H PF10181.4 EME83060.1 - 1.3e-25 88.8 0.1 1.9e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Arylsulfotran_2 PF14269.1 EME83061.1 - 1.4e-46 159.0 0.0 2e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME83061.1 - 4e-08 32.2 0.2 8.5e-08 31.1 0.1 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PAS_9 PF13426.1 EME83062.1 - 2.1e-12 47.3 0.0 1.3e-10 41.5 0.0 3.1 4 0 0 4 4 4 1 PAS domain ThiS PF02597.15 EME83063.1 - 2.2e-08 34.4 0.3 6.8e-08 32.8 0.2 1.7 1 1 0 1 1 1 1 ThiS family DUF1601 PF07671.6 EME83064.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DUF2689 PF10894.3 EME83065.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) ATPase_gene1 PF09527.5 EME83065.1 - 4.4 7.1 6.3 8 6.3 4.4 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) HECT PF00632.20 EME83066.1 - 6.2e-73 245.7 0.0 8.8e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) cwf21 PF08312.7 EME83066.1 - 2.8 7.8 5.1 2 8.3 0.6 2.3 2 0 0 2 2 2 0 cwf21 domain Ribosomal_L15e PF00827.12 EME83067.1 - 1.6e-91 305.0 12.2 1.8e-91 304.8 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 EME83067.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus Glyco_transf_90 PF05686.7 EME83068.1 - 6.1e-21 74.5 1.2 6.1e-21 74.5 0.8 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 90 Fungal_trans_2 PF11951.3 EME83069.1 - 7.1e-08 31.4 0.1 1.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 EME83071.1 - 6.3e-06 25.9 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EME83071.1 - 0.00024 20.4 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EME83071.1 - 0.0025 17.0 0.8 0.0094 15.1 0.5 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EME83071.1 - 0.0081 15.6 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EME83071.1 - 0.089 11.2 0.8 1.9 6.8 0.5 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PP-binding PF00550.20 EME83073.1 - 1.6e-17 63.5 1.6 5.9e-08 32.8 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site CN_hydrolase PF00795.17 EME83074.1 - 2.7e-34 118.1 0.0 4.2e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Oxysterol_BP PF01237.13 EME83075.1 - 8.6e-75 251.4 0.0 1.5e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein AMP-binding PF00501.23 EME83076.1 - 5.8e-56 189.6 0.0 2.2e-55 187.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EME83076.1 - 3.1e-13 49.7 0.0 1.4e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Hexapep PF00132.19 EME83076.1 - 1.9e-11 42.9 5.0 0.00034 19.9 0.0 5.5 6 0 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME83076.1 - 0.00029 20.3 8.6 0.54 9.8 0.4 5.2 4 2 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hydrolase_like PF13242.1 EME83077.1 - 2.5e-07 30.2 0.0 4.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EME83077.1 - 5e-06 26.8 0.0 1e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME83077.1 - 0.0019 18.6 0.0 0.0031 17.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NmrA PF05368.8 EME83078.1 - 0.17 11.1 0.0 17 4.5 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family ORMDL PF04061.9 EME83079.1 - 6.6e-59 197.3 5.9 7.6e-59 197.1 4.1 1.0 1 0 0 1 1 1 1 ORMDL family KASH PF10541.4 EME83079.1 - 0.089 12.6 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Nuclear envelope localisation domain SPC12 PF06645.8 EME83079.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Trep_Strep PF09605.5 EME83079.1 - 1.1 8.8 5.7 0.64 9.6 1.3 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) ArsA_ATPase PF02374.10 EME83081.1 - 2.1e-108 361.9 0.0 2.4e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EME83081.1 - 3.2e-17 62.6 0.6 6e-17 61.6 0.4 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME83081.1 - 3.4e-07 30.3 0.0 3.8e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EME83081.1 - 5e-07 29.1 0.1 1.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EME83081.1 - 7.2e-06 25.5 0.1 0.00036 20.0 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EME83081.1 - 0.00016 21.1 0.3 0.00066 19.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EME83081.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EME83081.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EME83081.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein MipZ PF09140.6 EME83081.1 - 0.011 14.7 0.1 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 ATPase MipZ Zeta_toxin PF06414.7 EME83081.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EME83081.1 - 0.034 13.5 0.1 0.05 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EME83081.1 - 0.039 12.8 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein VirC1 PF07015.6 EME83081.1 - 0.043 12.8 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 VirC1 protein YhjQ PF06564.7 EME83081.1 - 0.05 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 EME83081.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 EME83081.1 - 0.22 10.2 0.9 0.46 9.2 0.0 1.8 2 0 0 2 2 2 0 ArgK protein NDUFA12 PF05071.11 EME83082.1 - 1e-13 51.6 0.8 2.5e-13 50.3 0.6 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pkinase PF00069.20 EME83083.1 - 0.043 12.9 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EME83084.1 - 1.5e-17 63.6 0.0 2.2e-17 63.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83084.1 - 0.00012 21.2 0.0 0.00056 19.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EME83084.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transthyretin PF00576.16 EME83085.1 - 2.6e-27 94.9 0.1 1.1e-25 89.7 0.1 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family SnoaL_2 PF12680.2 EME83086.1 - 0.079 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Uricase PF01014.13 EME83087.1 - 0.05 13.6 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Uricase F-box-like PF12937.2 EME83088.1 - 0.0055 16.4 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like CorA PF01544.13 EME83089.1 - 1.4e-14 53.8 0.2 8.7e-14 51.2 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Amidohydro_4 PF13147.1 EME83090.1 - 1.7e-10 41.4 2.2 2.4e-10 40.9 1.5 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EME83090.1 - 8.9e-08 32.0 0.4 1.9e-07 30.9 0.3 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EME83090.1 - 0.00018 21.2 0.4 0.00045 19.9 0.3 1.6 1 1 0 1 1 1 1 Amidohydrolase family p450 PF00067.17 EME83091.1 - 9.1e-60 202.4 0.0 1.1e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M28 PF04389.12 EME83093.1 - 1e-34 119.8 0.0 2e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME83093.1 - 2.4e-15 56.0 0.3 6.6e-15 54.6 0.1 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EME83093.1 - 2.7e-05 23.7 0.0 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Alk_phosphatase PF00245.15 EME83095.1 - 4e-85 286.0 0.0 5.9e-50 170.1 0.0 2.2 1 1 1 2 2 2 2 Alkaline phosphatase Gly-zipper_Omp PF13488.1 EME83095.1 - 5.9e-05 22.6 1.3 5.9e-05 22.6 0.9 2.0 2 0 0 2 2 2 1 Glycine zipper Metalloenzyme PF01676.13 EME83095.1 - 0.00019 20.9 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Rick_17kDa_Anti PF05433.10 EME83095.1 - 0.00027 20.5 7.3 0.00027 20.5 5.1 2.5 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EME83095.1 - 0.0009 18.7 8.1 0.0009 18.7 5.6 2.3 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EME83095.1 - 0.0054 16.3 0.1 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Ceramidase_alk PF04734.8 EME83096.1 - 7.1e-265 880.1 0.0 8.1e-265 879.9 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 EME83097.1 - 3.1e-45 154.3 0.6 3.8e-45 154.0 0.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TBPIP PF07106.8 EME83097.1 - 0.018 14.6 1.1 0.028 13.9 0.8 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) T2SG PF08334.6 EME83098.1 - 0.071 12.8 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Fungal_trans PF04082.13 EME83099.1 - 4.6e-14 51.9 0.0 7.4e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Asp_Glu_race PF01177.17 EME83100.1 - 1.4e-15 57.8 0.0 1.6e-15 57.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 EME83100.1 - 0.16 11.3 0.5 5.9 6.1 0.0 2.5 2 2 0 2 2 2 0 AroM protein FMN_dh PF01070.13 EME83101.1 - 1.5e-111 372.7 0.0 2e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EME83101.1 - 2.1e-18 65.8 0.0 4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 EME83101.1 - 3.1e-06 26.5 0.0 9.2e-06 25.0 0.0 1.7 1 1 1 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 EME83101.1 - 8.6e-06 24.9 0.2 1.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EME83101.1 - 0.00015 20.7 2.7 0.00039 19.4 0.2 2.5 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.12 EME83101.1 - 0.036 13.1 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI ThiG PF05690.9 EME83101.1 - 0.055 12.5 0.2 0.35 9.9 0.1 2.0 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG AA_permease_2 PF13520.1 EME83102.1 - 2e-49 168.3 47.3 2.4e-49 168.0 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME83102.1 - 1.2e-13 50.2 33.5 1.6e-13 49.8 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_S10 PF00450.17 EME83103.1 - 5.5e-88 295.9 0.3 1.6e-87 294.3 0.2 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase GST_C_3 PF14497.1 EME83104.1 - 2.9e-11 43.7 0.1 6.4e-11 42.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME83104.1 - 4.9e-05 23.1 0.0 9.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME83104.1 - 0.0017 18.5 0.0 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME83104.1 - 0.0076 16.2 0.0 0.097 12.6 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyr_redox_3 PF13738.1 EME83105.1 - 7.7e-19 68.5 0.0 1.3e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME83105.1 - 9.1e-10 37.3 0.0 1.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME83105.1 - 1e-07 31.8 0.1 9.5e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME83105.1 - 1e-07 31.2 0.0 4e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EME83105.1 - 0.0017 17.3 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME83105.1 - 0.016 14.9 0.4 2.1 8.0 0.1 3.5 3 1 0 3 3 3 0 FAD-NAD(P)-binding Meth_synt_2 PF01717.13 EME83106.1 - 0.00057 18.9 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain RabGAP-TBC PF00566.13 EME83107.1 - 4.9e-48 163.4 0.0 9.1e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Filament PF00038.16 EME83107.1 - 0.00086 18.8 2.8 0.00086 18.8 1.9 2.4 2 0 0 2 2 2 1 Intermediate filament protein DUF2312 PF10073.4 EME83107.1 - 0.097 12.0 2.6 0.38 10.1 0.5 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Macoilin PF09726.4 EME83107.1 - 0.1 10.8 16.4 0.23 9.6 1.6 2.3 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.9 EME83107.1 - 0.26 10.8 26.8 0.021 14.4 8.1 2.8 3 0 0 3 3 3 0 IncA protein APG6 PF04111.7 EME83107.1 - 3.8 6.4 20.9 0.2 10.6 6.2 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EME83107.1 - 4.8 7.2 18.7 0.45 10.4 7.7 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 EME83107.1 - 6.8 7.0 11.3 17 5.8 0.9 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EME83107.1 - 8.1 6.1 11.0 11 5.7 0.5 2.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.20 EME83108.1 - 5.7e-21 74.8 0.0 2.4e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME83108.1 - 1e-07 31.3 0.0 3.8e-06 26.1 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase EMP24_GP25L PF01105.19 EME83109.1 - 1.6e-40 138.7 0.0 2e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cupin_1 PF00190.17 EME83110.1 - 1e-27 96.3 0.0 4.2e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EME83110.1 - 1.4e-25 88.5 0.1 1.8e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EME83110.1 - 6.8e-10 38.1 0.0 0.00075 18.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EME83110.1 - 3.3e-09 36.5 0.0 5.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EME83110.1 - 9.7e-07 28.5 0.4 0.00045 19.9 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.7 EME83110.1 - 0.00012 21.5 0.0 0.00046 19.6 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.2 EME83110.1 - 0.00017 21.2 0.0 0.033 13.8 0.0 2.3 2 0 0 2 2 2 1 Cupin Auxin_BP PF02041.11 EME83110.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Auxin binding protein Cupin_4 PF08007.7 EME83110.1 - 0.033 13.4 0.1 0.19 10.9 0.0 2.1 2 1 0 2 2 2 0 Cupin superfamily protein DUF1971 PF09313.6 EME83110.1 - 0.038 13.7 0.1 5.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) 2OG-FeII_Oxy_5 PF13759.1 EME83110.1 - 0.08 13.2 0.6 3.7 7.8 0.2 3.1 3 1 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase ARD PF03079.9 EME83110.1 - 0.086 12.7 0.0 17 5.3 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family ZF-HD_dimer PF04770.7 EME83111.1 - 0.087 12.8 1.6 0.15 12.1 1.1 1.4 1 0 0 1 1 1 0 ZF-HD protein dimerisation region RNA_pol_Rpb4 PF03874.11 EME83112.1 - 8.7e-08 32.1 1.8 1.3e-07 31.6 1.3 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Tox-REase-3 PF15647.1 EME83112.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 RPAP1_N PF08621.5 EME83112.1 - 0.093 12.3 0.2 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal DUF2785 PF10978.3 EME83112.1 - 0.11 11.8 0.2 0.27 10.6 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2785) adh_short PF00106.20 EME83113.1 - 4.7e-27 94.9 0.0 1e-26 93.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME83113.1 - 8.7e-11 41.8 0.0 2.7e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME83113.1 - 6e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME83113.1 - 9.1e-10 38.8 0.0 4.7e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME83113.1 - 0.00086 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME83113.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EME83113.1 - 0.0096 14.6 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Myco_arth_vir_N PF09610.5 EME83113.1 - 0.016 15.1 0.6 0.016 15.1 0.4 2.0 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) GTP1_OBG PF01018.17 EME83114.1 - 5e-40 136.6 2.3 1.4e-30 106.0 1.5 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EME83114.1 - 1e-21 77.0 0.0 2e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME83114.1 - 5.4e-08 32.2 0.0 1.4e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EME83114.1 - 0.004 15.9 0.3 0.077 11.7 0.0 2.4 3 0 0 3 3 3 1 ArgK protein ABC_tran PF00005.22 EME83114.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 EME83114.1 - 0.02 14.7 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 EME83114.1 - 0.09 13.2 0.0 0.67 10.4 0.0 2.3 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EME83114.1 - 0.13 11.6 0.0 9.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EME83114.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ADH_N PF08240.7 EME83115.1 - 4.3e-22 77.9 3.3 6.5e-22 77.3 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83115.1 - 5.9e-16 58.1 0.0 9.5e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME83115.1 - 1.6e-10 41.9 0.0 3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME83115.1 - 0.0074 15.4 0.1 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_28 PF00295.12 EME83116.1 - 2.6e-46 158.1 5.7 5.6e-46 157.0 3.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Thiolase_C PF02803.13 EME83117.1 - 7.7e-11 41.4 1.3 3e-10 39.5 0.1 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EME83117.1 - 1.9e-05 24.2 0.0 6e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EME83117.1 - 4.6e-05 23.0 0.2 0.00012 21.6 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EME83117.1 - 0.00066 18.7 0.0 0.0012 17.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SpoVAD PF07451.6 EME83117.1 - 0.022 13.1 0.6 0.07 11.5 0.1 1.9 2 1 1 3 3 3 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 EME83117.1 - 0.073 12.9 0.4 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain ATP-synt_E PF05680.7 EME83118.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 ATP synthase E chain Pex24p PF06398.6 EME83119.1 - 0.0001 21.2 7.5 0.0001 21.2 5.2 2.0 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Apolipoprotein PF01442.13 EME83120.1 - 0.00086 18.8 1.1 0.0013 18.3 0.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phage_min_cap2 PF06152.6 EME83120.1 - 0.01 14.8 2.9 0.012 14.6 2.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 OmpH PF03938.9 EME83120.1 - 0.019 14.8 7.7 0.025 14.5 5.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4482 PF14818.1 EME83120.1 - 0.028 15.0 3.4 0.032 14.8 2.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4482) His_Phos_2 PF00328.17 EME83120.1 - 0.043 13.1 0.1 0.046 13.0 0.1 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF3713 PF12506.3 EME83120.1 - 0.045 13.8 3.9 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) Octopine_DH PF02317.12 EME83120.1 - 0.11 12.1 1.1 0.19 11.3 0.5 1.5 1 1 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Prominin PF05478.6 EME83120.1 - 0.13 9.7 1.9 0.16 9.4 1.3 1.1 1 0 0 1 1 1 0 Prominin KfrA_N PF11740.3 EME83120.1 - 0.27 11.6 4.9 0.39 11.1 3.4 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF1525 PF07511.6 EME83120.1 - 0.67 9.9 3.7 15 5.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) ATP-synt_B PF00430.13 EME83120.1 - 0.83 9.4 19.3 0.13 12.1 9.0 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G PF03179.10 EME83120.1 - 1.3 9.3 18.2 2 8.7 10.5 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF2317 PF10079.4 EME83120.1 - 1.8 7.0 5.5 2.1 6.8 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) RRF PF01765.14 EME83120.1 - 4.9 6.5 8.3 9 5.7 5.8 1.6 1 1 0 1 1 1 0 Ribosome recycling factor DUF883 PF05957.8 EME83120.1 - 5.3 7.5 18.1 0.12 12.8 5.3 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF883) Activator-TraM PF11657.3 EME83120.1 - 9.1 5.7 9.0 11 5.5 5.9 1.4 1 1 0 1 1 1 0 Transcriptional activator TraM DivIVA PF05103.8 EME83120.1 - 9.5 6.2 13.9 0.72 9.9 4.4 2.4 1 1 2 3 3 3 0 DivIVA protein F-box-like PF12937.2 EME83121.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like DDE_Tnp_1_2 PF13586.1 EME83123.1 - 0.58 10.3 3.9 0.59 10.3 0.1 3.0 3 0 0 3 3 3 0 Transposase DDE domain DivIC PF04977.10 EME83123.1 - 7.1 6.1 8.3 1.1 8.8 2.2 2.2 2 0 0 2 2 2 0 Septum formation initiator UDPG_MGDP_dh_N PF03721.9 EME83125.1 - 7.3e-16 58.0 0.1 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EME83125.1 - 8.3e-16 57.9 0.0 2.4e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EME83125.1 - 2.3e-06 27.6 0.0 5.7e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Glyco_tranf_2_3 PF13641.1 EME83126.1 - 1e-17 64.6 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME83126.1 - 1.5e-07 31.3 1.2 1.5e-07 31.3 0.9 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EME83126.1 - 7.8e-05 22.0 0.0 0.0005 19.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME83126.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4149 PF13664.1 EME83126.1 - 5.9 7.0 10.2 0.082 12.9 0.6 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Amidohydro_1 PF01979.15 EME83129.1 - 5.7e-62 210.2 0.8 9.4e-62 209.5 0.6 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EME83129.1 - 3.6e-55 185.2 3.5 8.1e-55 184.1 2.4 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EME83129.1 - 1.5e-40 137.1 0.7 2.9e-40 136.1 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EME83129.1 - 3.3e-37 126.4 0.1 6.7e-37 125.4 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.6 EME83129.1 - 1.5e-05 24.3 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EME83129.1 - 0.00022 20.9 3.5 0.00067 19.4 2.4 1.9 1 0 0 1 1 1 1 Amidohydrolase An_peroxidase PF03098.10 EME83130.1 - 6.5e-122 407.6 0.0 7.5e-122 407.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase XLF PF09302.6 EME83131.1 - 2.5e-18 66.4 0.0 2.5e-18 66.4 0.0 1.8 3 0 0 3 3 3 1 XLF (XRCC4-like factor) Cactin_mid PF10312.4 EME83132.1 - 6.6e-58 195.1 0.6 9.7e-58 194.5 0.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EME83132.1 - 9.6e-55 183.5 3.8 1.4e-54 182.9 2.7 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 EME83133.1 - 9.5e-13 48.0 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FUSC PF04632.7 EME83133.1 - 4.3 5.6 6.1 5.9 5.1 4.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3328 PF11807.3 EME83135.1 - 7.3e-31 107.5 3.2 8.9e-31 107.2 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Metallophos PF00149.23 EME83137.1 - 1e-09 38.0 8.2 2.2e-09 36.9 5.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SAD_SRA PF02182.12 EME83138.1 - 5.8e-32 110.1 0.1 9e-32 109.5 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain AAL_decarboxy PF03306.8 EME83140.1 - 3.2e-35 121.1 0.0 1.6e-22 79.6 0.0 2.0 1 1 1 2 2 2 2 Alpha-acetolactate decarboxylase ApbA PF02558.11 EME83141.1 - 3.6e-27 94.6 0.0 1.1e-26 93.0 0.0 1.8 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EME83141.1 - 2e-24 85.9 0.0 2.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_10 PF13460.1 EME83141.1 - 0.0027 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 EME83141.1 - 0.0049 17.0 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 EME83141.1 - 0.068 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phostensin_N PF13916.1 EME83142.1 - 0.063 13.2 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal GKAP PF03359.8 EME83143.1 - 9.1 5.7 10.3 10 5.6 6.5 1.5 1 1 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein FMO-like PF00743.14 EME83144.1 - 4.2e-15 54.9 0.0 2.8e-13 48.9 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME83144.1 - 2.2e-10 40.9 0.0 9.6e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME83144.1 - 3.6e-07 30.1 0.0 8.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME83144.1 - 0.1 11.5 0.0 24 3.6 0.0 3.1 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) CHORD PF04968.7 EME83145.1 - 0.0015 18.7 0.1 0.0025 18.0 0.1 1.3 1 0 0 1 1 1 1 CHORD ECH PF00378.15 EME83146.1 - 1.1e-37 129.4 0.1 1e-36 126.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Actin PF00022.14 EME83147.1 - 1.1e-129 432.2 0.0 1.3e-129 432.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME83147.1 - 0.00039 19.1 0.0 0.063 11.8 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein DUF3602 PF12223.3 EME83148.1 - 8.7e-12 45.2 6.4 3.4e-08 33.7 0.5 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Oxysterol_BP PF01237.13 EME83150.1 - 1.7e-113 378.7 0.0 3.3e-113 377.7 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EME83150.1 - 3e-36 123.3 0.1 7.1e-36 122.1 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EME83150.1 - 0.00026 21.1 0.0 0.00064 19.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EME83150.1 - 0.025 14.8 1.6 0.39 10.9 1.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain UQ_con PF00179.21 EME83151.1 - 2.7e-37 127.3 0.0 3.8e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME83151.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B MOSC_N PF03476.11 EME83152.1 - 1.4e-19 69.9 0.0 2.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EME83152.1 - 1.3e-18 66.7 0.0 2.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Asp PF00026.18 EME83154.1 - 2.2e-08 33.7 0.4 1.2e-07 31.2 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Rax2 PF12768.2 EME83154.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM51 PF15345.1 EME83154.1 - 0.045 13.4 0.3 0.088 12.4 0.2 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.5 EME83154.1 - 0.048 12.9 2.6 0.1 11.9 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 EME83154.1 - 0.22 10.0 0.3 0.37 9.3 0.0 1.4 2 0 0 2 2 2 0 Giardia variant-specific surface protein C2 PF00168.25 EME83156.1 - 4.3e-13 48.9 0.0 9.3e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain TMEM171 PF15471.1 EME83156.1 - 5.8 5.6 6.1 11 4.6 4.3 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 CbiM PF01891.11 EME83157.1 - 5.1 6.6 13.5 12 5.4 6.4 2.7 2 1 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region Sugar_tr PF00083.19 EME83159.1 - 1.3e-76 258.0 24.4 1.6e-76 257.7 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83159.1 - 1.9e-16 59.7 29.5 1.9e-16 59.7 20.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME83159.1 - 0.0021 16.5 28.3 0.014 13.8 2.2 3.4 2 2 0 3 3 3 2 MFS/sugar transport protein DnaJ PF00226.26 EME83160.1 - 0.011 15.3 0.1 0.011 15.3 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain DUF2828 PF11443.3 EME83160.1 - 0.8 7.8 11.1 1.2 7.2 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spore_coat_CotO PF14153.1 EME83160.1 - 1.2 8.5 16.1 0.023 14.1 5.3 2.0 2 0 0 2 2 2 0 Spore coat protein CotO CDC45 PF02724.9 EME83160.1 - 3.4 5.6 18.1 0.022 12.8 6.7 1.5 2 0 0 2 2 2 0 CDC45-like protein Pex14_N PF04695.8 EME83160.1 - 4 7.4 10.4 4.3 7.3 6.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOBP PF15279.1 EME83160.1 - 6.8 6.9 11.0 9 6.5 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein LicD PF04991.8 EME83163.1 - 1.1e-33 117.0 5.6 8.7e-33 114.1 3.8 2.1 1 1 0 1 1 1 1 LicD family Amidase PF01425.16 EME83164.1 - 1.7e-88 297.4 0.0 2e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Aldose_epim PF01263.15 EME83165.1 - 6.6e-50 169.9 0.6 7.8e-50 169.6 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldedh PF00171.17 EME83166.1 - 3.5e-134 447.6 0.2 3.9e-134 447.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage-MuB_C PF09077.6 EME83166.1 - 0.041 13.5 0.4 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Mu B transposition protein, C terminal PP2C PF00481.16 EME83167.1 - 2.1e-36 125.6 0.0 4.2e-36 124.6 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EME83167.1 - 0.0003 20.2 0.0 0.0006 19.2 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME83167.1 - 0.004 16.8 0.0 3.3 7.3 0.0 3.1 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Lac_bphage_repr PF06543.7 EME83167.1 - 0.019 14.4 0.1 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Glyco_hydro_53 PF07745.8 EME83168.1 - 2e-81 273.3 0.2 2.3e-81 273.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 EME83168.1 - 0.021 14.0 0.1 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Peroxidase_2 PF01328.12 EME83171.1 - 7.6e-18 64.2 1.2 1.8e-17 63.0 0.8 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 zf-U11-48K PF05253.7 EME83171.1 - 5.5 6.8 5.0 1.5 8.5 0.4 2.3 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger PDGLE PF13190.1 EME83172.1 - 0.086 12.5 1.7 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 PDGLE domain Dak2 PF02734.12 EME83173.1 - 0.0061 16.2 0.0 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 DAK2 domain Alpha-amylase PF00128.19 EME83175.1 - 3.8e-70 236.7 0.2 5.3e-70 236.3 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 EME83175.1 - 1.9e-29 101.0 0.6 4.8e-29 99.8 0.4 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 EME83175.1 - 4.1e-19 68.4 0.3 1.3e-18 66.7 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_25 PF03423.8 EME83175.1 - 0.0089 16.0 0.3 0.041 13.9 0.1 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain (family 25) MFS_1 PF07690.11 EME83176.1 - 1.6e-25 89.5 30.4 2.8e-25 88.7 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ig_J_chain PF15097.1 EME83178.1 - 1.6 8.3 7.3 0.28 10.7 0.8 2.4 2 1 1 3 3 3 0 Immunoglobulin J chain S1-P1_nuclease PF02265.11 EME83179.1 - 1.5e-41 142.6 0.0 1.9e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Prok-RING_1 PF14446.1 EME83179.1 - 0.0039 16.8 0.2 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 RB_B PF01857.15 EME83180.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain CLTH PF10607.4 EME83181.1 - 7.1e-24 84.1 0.0 4.5e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EME83181.1 - 2.2e-15 56.0 1.3 4.5e-15 55.0 0.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EME83181.1 - 0.00016 21.3 0.4 0.00028 20.6 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME83181.1 - 0.0022 17.9 0.8 0.0038 17.2 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EME83181.1 - 0.0045 16.2 0.1 0.0045 16.2 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_5 PF14634.1 EME83181.1 - 0.0097 15.6 0.4 0.017 14.8 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME83181.1 - 0.019 14.6 0.8 0.031 13.9 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME83181.1 - 0.06 13.0 0.8 0.1 12.2 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME83181.1 - 0.16 11.8 0.8 0.34 10.8 0.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Syntaxin-6_N PF09177.6 EME83181.1 - 0.27 11.6 1.8 0.65 10.4 0.3 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 EME83181.1 - 1.7 7.0 5.6 0.32 9.3 1.6 1.5 2 0 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 EME83181.1 - 2.7 7.7 5.7 2.3 7.9 1.0 2.5 1 1 1 2 2 2 0 Prefoldin subunit Laminin_II PF06009.7 EME83182.1 - 0.032 13.9 0.4 0.43 10.3 0.0 2.6 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 EME83182.1 - 0.12 10.9 5.1 0.049 12.2 1.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein PG_binding_1 PF01471.13 EME83182.1 - 0.14 12.1 0.6 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Putative peptidoglycan binding domain CENP-F_leu_zip PF10473.4 EME83182.1 - 0.23 11.3 10.2 7.5 6.4 0.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EME83182.1 - 0.37 10.6 1.6 5.1 6.8 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EME83182.1 - 0.39 10.8 5.5 1.4 9.0 0.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EME83182.1 - 0.4 10.6 4.8 6.4 6.7 0.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) WD40 PF00400.27 EME83183.1 - 2.3e-28 96.9 14.7 3e-07 30.0 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EME83183.1 - 8.3e-07 28.9 0.7 0.00052 19.7 0.1 3.0 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.1 EME83184.1 - 6.2e-25 86.7 11.9 1.5e-07 31.0 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EME83184.1 - 9.1e-25 86.1 0.8 1.6e-06 27.9 0.0 5.2 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EME83184.1 - 2.3e-21 74.9 3.0 3.6e-05 23.7 0.1 5.8 3 1 2 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EME83184.1 - 1.1e-17 63.5 15.1 9.8e-07 28.7 0.0 6.9 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EME83184.1 - 4.9e-17 61.2 0.5 0.00014 21.3 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EME83184.1 - 6.7e-17 60.5 6.8 7.5e-06 25.5 0.2 5.4 6 0 0 6 6 6 4 Kelch motif BTB PF00651.26 EME83184.1 - 4.8e-11 42.6 0.0 9.1e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain COQ7 PF03232.8 EME83188.1 - 7.2e-64 214.3 0.0 9.2e-64 214.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EME83188.1 - 0.00018 21.8 0.1 0.00041 20.6 0.1 1.7 1 1 0 1 1 1 1 Rubrerythrin CKAP2_C PF15297.1 EME83188.1 - 0.027 13.3 0.9 0.031 13.1 0.0 1.4 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus UPF0184 PF03670.8 EME83188.1 - 0.11 12.6 1.9 0.58 10.3 1.3 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Plus-3 PF03126.13 EME83189.1 - 7.7e-31 106.3 0.0 1.9e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain PhyH PF05721.8 EME83192.1 - 1.2e-56 192.1 0.0 1.4e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UPF0546 PF10639.4 EME83193.1 - 1.1e-38 131.5 0.2 1.6e-38 131.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EME83193.1 - 0.0013 18.7 5.6 0.0029 17.6 2.1 2.2 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EME83193.1 - 0.0068 16.5 2.2 0.0068 16.5 1.6 1.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF485 PF04341.7 EME83193.1 - 0.65 9.7 3.1 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF485 DUF4131 PF13567.1 EME83193.1 - 1 8.7 5.4 6.4 6.1 2.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.19 EME83195.1 - 3.7e-58 197.1 9.8 5.2e-58 196.7 6.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83195.1 - 9.1e-21 73.9 12.9 1.3e-20 73.4 8.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily KbaA PF14089.1 EME83195.1 - 0.016 14.7 4.6 0.044 13.3 3.2 1.7 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation Pkinase PF00069.20 EME83196.1 - 4.2e-07 29.3 0.0 1.4e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83196.1 - 0.0062 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Potyvirid-P3 PF13608.1 EME83196.1 - 0.075 12.1 0.1 8.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein Snf7 PF03357.16 EME83196.1 - 0.42 9.9 3.4 1.3 8.3 2.3 1.8 1 1 0 1 1 1 0 Snf7 Pkinase PF00069.20 EME83197.1 - 5.3e-74 248.6 0.0 7.4e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83197.1 - 7.3e-39 133.3 0.0 1.1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EME83197.1 - 1.2e-15 57.4 0.2 2.6e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EME83197.1 - 1.1e-07 31.0 0.0 4.1e-07 29.2 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EME83197.1 - 0.0011 18.3 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EME83197.1 - 0.0051 15.4 0.1 0.0078 14.8 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EME83197.1 - 0.029 13.4 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PLDc PF00614.17 EME83198.1 - 4.6e-15 54.8 1.0 4.7e-08 32.5 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EME83198.1 - 1.7e-11 43.9 0.0 3.1e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EME83198.1 - 4.7e-10 39.2 1.0 1.6e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 PX domain PH PF00169.24 EME83198.1 - 0.067 13.4 0.2 0.55 10.4 0.1 2.5 3 0 0 3 3 3 0 PH domain 2TM PF13239.1 EME83199.1 - 0.095 12.7 12.6 0.19 11.7 3.3 2.9 2 1 1 3 3 3 0 2TM domain DUF1469 PF07332.6 EME83199.1 - 0.27 10.9 7.1 0.41 10.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF307 PF03733.8 EME83201.1 - 0.64 10.4 4.1 1.2 9.6 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF307) AMP-binding PF00501.23 EME83203.1 - 8.9e-70 235.1 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME83203.1 - 2.4e-10 41.2 0.1 1e-09 39.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DEPP PF15343.1 EME83204.1 - 0.031 13.9 0.5 0.038 13.5 0.3 1.1 1 0 0 1 1 1 0 Decidual protein induced by progesterone family tRNA-synt_1 PF00133.17 EME83207.1 - 1.4e-197 657.4 0.0 1.1e-196 654.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME83207.1 - 4e-24 85.1 0.0 2.7e-22 79.1 0.0 2.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME83207.1 - 1.9e-18 66.3 0.0 1.6e-06 27.0 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) DUF3801 PF12687.2 EME83207.1 - 0.0052 16.3 0.8 0.011 15.3 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) tRNA-synt_1e PF01406.14 EME83207.1 - 0.024 13.7 0.0 0.094 11.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain AMP-binding PF00501.23 EME83210.1 - 1.1e-60 205.1 0.0 1.6e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EME83210.1 - 2e-22 80.5 0.0 4.4e-22 79.4 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EME83210.1 - 1.8e-05 24.7 0.0 4.9e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME83210.1 - 0.0024 17.2 0.0 0.0051 16.1 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EME83210.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold ApbA PF02558.11 EME83211.1 - 4e-21 75.0 0.0 5.5e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EME83211.1 - 4.3e-21 75.1 0.0 1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Transferase PF02458.10 EME83212.1 - 2.2e-22 79.1 0.0 1.1e-20 73.5 0.0 2.7 1 1 0 1 1 1 1 Transferase family adh_short PF00106.20 EME83214.1 - 3.2e-27 95.4 1.4 4.2e-27 95.0 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME83214.1 - 5.2e-22 78.8 0.4 9.1e-22 77.9 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME83214.1 - 2.2e-12 47.0 2.4 5.6e-12 45.7 1.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME83214.1 - 3.7e-07 29.8 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4470 PF14737.1 EME83216.1 - 5.2e-25 87.0 0.1 1.2e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EME83216.1 - 9.4e-10 38.2 17.7 1.9e-09 37.2 12.3 1.5 1 0 0 1 1 1 1 MYND finger Gag_p15 PF08723.5 EME83216.1 - 0.11 12.5 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Gag protein p15 DUF2787 PF10980.3 EME83216.1 - 0.14 12.0 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2787) PTR2 PF00854.16 EME83217.1 - 4e-35 121.3 11.8 4e-34 118.0 7.0 3.3 2 1 0 2 2 2 1 POT family Arylsulfotran_2 PF14269.1 EME83218.1 - 2.3e-42 145.2 1.6 2.3e-42 145.2 1.1 1.8 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME83218.1 - 1.1e-12 47.2 4.1 1.1e-12 47.2 2.9 2.8 2 1 0 2 2 2 1 Arylsulfotransferase (ASST) FMN_dh PF01070.13 EME83219.1 - 2.4e-87 293.0 0.2 9.4e-49 166.1 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EME83219.1 - 5.3e-05 22.2 0.2 0.00037 19.5 0.0 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EME83219.1 - 0.00026 20.0 0.0 0.00044 19.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EME83219.1 - 0.012 14.9 0.2 0.19 10.9 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein MRP-S26 PF14943.1 EME83221.1 - 0.096 12.2 11.2 0.14 11.6 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3391 PF11871.3 EME83221.1 - 0.19 11.9 11.5 0.1 12.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Glyco_hydro_77 PF02446.12 EME83221.1 - 1.9 6.9 5.0 2.4 6.6 3.5 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase UQ_con PF00179.21 EME83222.1 - 3.9e-43 146.2 0.0 4.8e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME83222.1 - 0.0031 17.2 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME83222.1 - 0.008 16.0 0.1 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Nsp1_C PF05064.8 EME83223.1 - 2.2e-28 98.2 1.4 2.2e-28 98.2 0.9 2.1 2 1 0 2 2 2 1 Nsp1-like C-terminal region MscS_porin PF12795.2 EME83223.1 - 8.2e-05 22.0 9.1 0.011 15.0 0.1 2.1 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain DUF869 PF05911.6 EME83223.1 - 0.00013 20.3 2.5 0.00016 20.0 1.7 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) GAS PF13851.1 EME83223.1 - 0.0037 16.4 1.6 0.87 8.7 0.0 2.2 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EME83223.1 - 0.0039 15.7 5.9 0.0097 14.4 4.1 1.6 1 1 0 1 1 1 1 AAA domain Lip_prot_lig_C PF10437.4 EME83223.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus APG6 PF04111.7 EME83223.1 - 0.016 14.2 8.2 0.052 12.6 2.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 WXG100 PF06013.7 EME83223.1 - 0.018 15.0 9.4 7.7 6.5 0.0 4.3 3 1 1 4 4 4 0 Proteins of 100 residues with WXG PE PF00934.15 EME83223.1 - 0.023 14.7 0.9 3 7.9 0.0 2.4 2 0 0 2 2 2 0 PE family Prefoldin_2 PF01920.15 EME83223.1 - 0.024 14.3 8.5 0.029 14.1 0.5 3.6 1 1 0 3 3 3 0 Prefoldin subunit CENP-Q PF13094.1 EME83223.1 - 0.029 14.4 6.6 1.4 8.8 4.6 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4559 PF15112.1 EME83223.1 - 0.032 13.4 6.9 0.29 10.2 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) ADIP PF11559.3 EME83223.1 - 0.048 13.5 11.1 0.16 11.8 0.3 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ALIX_LYPXL_bnd PF13949.1 EME83223.1 - 0.056 12.4 4.5 0.17 10.8 1.0 2.5 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Streptin-Immun PF11083.3 EME83223.1 - 0.063 13.2 2.0 0.5 10.3 0.1 2.9 3 1 0 3 3 2 0 Lantibiotic streptin immunity protein DUF641 PF04859.7 EME83223.1 - 0.069 12.9 3.1 0.34 10.6 0.1 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 EME83223.1 - 0.1 12.4 10.3 0.042 13.7 1.5 2.6 2 1 0 2 2 2 0 Tropomyosin like GTPase_Cys_C PF12631.2 EME83223.1 - 0.11 12.9 0.8 21 5.6 0.0 3.1 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF4200 PF13863.1 EME83223.1 - 0.13 12.2 6.2 0.19 11.7 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EME83223.1 - 0.13 11.4 7.1 0.89 8.6 2.1 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EME83223.1 - 0.16 10.5 5.5 0.64 8.6 0.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EME83223.1 - 0.21 10.9 8.6 0.4 10.0 0.6 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EME83223.1 - 0.23 9.8 3.9 0.49 8.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMCO5 PF14992.1 EME83223.1 - 0.27 10.3 4.6 0.83 8.7 0.5 2.0 2 0 0 2 2 2 0 TMCO5 family HrpB7 PF09486.5 EME83223.1 - 0.28 11.0 6.9 1.5 8.6 0.9 3.0 2 2 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Tropomyosin PF00261.15 EME83223.1 - 0.37 9.8 5.6 0.15 11.0 0.8 2.2 1 1 0 1 1 1 0 Tropomyosin ATG16 PF08614.6 EME83223.1 - 0.37 10.6 12.1 0.084 12.6 1.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EME83223.1 - 0.43 8.2 8.7 0.1 10.3 1.3 2.0 1 1 0 1 1 1 0 Myosin tail DUF3450 PF11932.3 EME83223.1 - 0.47 9.6 10.3 0.18 11.0 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Surfac_D-trimer PF09006.6 EME83223.1 - 0.54 10.0 0.1 0.54 10.0 0.1 2.6 3 0 0 3 3 2 0 Lung surfactant protein D coiled-coil trimerisation CENP-F_leu_zip PF10473.4 EME83223.1 - 0.64 9.8 9.2 1.7 8.5 1.2 3.2 2 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG17 PF04108.7 EME83223.1 - 0.73 8.5 6.0 1.1 7.9 0.3 2.4 1 1 2 3 3 3 0 Autophagy protein Apg17 Mod_r PF07200.8 EME83223.1 - 0.89 9.4 7.3 2 8.3 1.6 2.9 2 2 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.7 EME83223.1 - 1.3 8.8 4.8 5.5 6.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4298 PF14131.1 EME83223.1 - 1.4 8.8 6.3 8.4 6.3 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4298) RmuC PF02646.11 EME83223.1 - 1.6 7.4 7.3 10 4.8 0.4 2.8 2 2 1 3 3 3 0 RmuC family T4SS PF07996.6 EME83223.1 - 1.7 8.4 11.4 6.3 6.5 2.6 2.8 1 1 1 2 2 2 0 Type IV secretion system proteins Prefoldin PF02996.12 EME83223.1 - 1.9 8.1 9.1 15 5.2 0.3 3.8 3 1 1 4 4 4 0 Prefoldin subunit OmpH PF03938.9 EME83223.1 - 2.1 8.2 7.6 2e+02 1.8 5.3 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EME83223.1 - 2.4 7.7 7.1 1.5e+02 1.8 4.9 2.4 1 1 0 1 1 1 0 IncA protein Apolipoprotein PF01442.13 EME83223.1 - 2.6 7.4 7.4 45 3.4 5.1 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4164 PF13747.1 EME83223.1 - 3.9 7.6 6.6 5.3 7.2 0.4 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) Terpene_synth_C PF03936.11 EME83224.1 - 1.6e-07 30.8 0.1 1.9e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain GATase PF00117.23 EME83225.1 - 8e-07 28.6 0.0 1.5e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Amidase PF01425.16 EME83226.1 - 1.6e-81 274.4 2.0 1.1e-56 192.6 0.0 2.4 2 1 0 2 2 2 2 Amidase Hydantoinase_A PF01968.13 EME83227.1 - 9e-80 267.8 4.6 2.8e-79 266.2 1.5 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EME83227.1 - 3.1e-66 223.6 0.0 5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EME83227.1 - 8.2e-45 152.4 0.0 5e-42 143.3 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EME83227.1 - 1.9e-05 23.2 2.0 0.015 13.6 0.1 2.7 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.15 EME83227.1 - 0.0016 17.8 0.3 0.028 13.7 0.0 2.3 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DDA1 PF10172.4 EME83228.1 - 0.03 14.1 0.4 0.064 13.0 0.3 1.6 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase cNMP_binding PF00027.24 EME83229.1 - 5.5e-40 135.0 0.0 1e-18 66.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EME83229.1 - 1.9e-10 39.9 0.1 4.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit WHG PF13305.1 EME83231.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.5 2 0 0 2 2 2 0 WHG domain Opy2 PF09463.5 EME83234.1 - 1.5e-06 28.1 19.5 2.5e-06 27.4 13.5 1.4 1 0 0 1 1 1 1 Opy2 protein DUF1191 PF06697.7 EME83234.1 - 0.00052 18.9 0.1 0.00082 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 EME83234.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Cyt_c_ox_IV PF12270.3 EME83234.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV LRR_8 PF13855.1 EME83235.1 - 0.003 17.2 0.9 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat Snf7 PF03357.16 EME83236.1 - 3.4e-35 120.9 22.7 3.4e-35 120.9 15.7 1.5 2 0 0 2 2 2 1 Snf7 MutS_III PF05192.13 EME83236.1 - 1.3 8.7 6.9 0.66 9.7 3.2 1.7 1 1 0 1 1 1 0 MutS domain III Phage_GP20 PF06810.6 EME83236.1 - 6.5 6.1 19.0 0.94 8.9 5.9 2.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 Ten1 PF12658.2 EME83237.1 - 1.8e-13 50.3 0.0 1.8e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit MFS_1 PF07690.11 EME83238.1 - 2.6e-40 138.2 43.1 2.6e-40 138.2 29.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Plectin PF00681.15 EME83238.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Plectin repeat PAP_central PF04928.12 EME83238.1 - 0.21 10.3 0.3 0.34 9.6 0.2 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF1689 PF07954.6 EME83238.1 - 0.43 10.4 4.3 0.76 9.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) adh_short PF00106.20 EME83239.1 - 0.023 14.6 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Gln-synt_C PF00120.19 EME83240.1 - 8.7e-60 202.0 0.0 1.1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EME83240.1 - 5.5e-18 64.3 0.0 1.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Med1 PF10744.4 EME83242.1 - 1.4e-28 99.7 0.0 8.2e-28 97.2 0.0 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Glyco_hydro_3 PF00933.16 EME83243.1 - 6e-63 212.5 0.0 8.4e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME83243.1 - 4.8e-61 206.1 0.0 6.8e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME83243.1 - 4.3e-21 74.6 0.4 1.1e-20 73.3 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain CARDB PF07705.6 EME83243.1 - 0.023 14.7 0.4 0.052 13.5 0.3 1.6 1 0 0 1 1 1 0 CARDB Sugar-bind PF04198.8 EME83243.1 - 0.027 13.3 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Sds3 PF08598.6 EME83244.1 - 2.3e-38 131.8 0.3 2.9e-38 131.4 0.2 1.2 1 0 0 1 1 1 1 Sds3-like DUF4201 PF13870.1 EME83244.1 - 0.19 11.1 10.9 0.04 13.3 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1814 PF08843.6 EME83244.1 - 0.2 11.3 2.4 1.1 8.9 1.7 2.1 1 1 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) OmpH PF03938.9 EME83244.1 - 0.3 11.0 4.5 0.96 9.3 3.1 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EME83244.1 - 0.41 10.2 7.0 0.85 9.1 4.9 1.4 1 0 0 1 1 1 0 IncA protein NmrA PF05368.8 EME83245.1 - 4.7e-15 55.4 0.0 6.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME83245.1 - 7.9e-14 52.0 0.4 1.3e-13 51.3 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EME83245.1 - 0.00019 21.6 0.1 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EME83245.1 - 0.00053 19.4 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME83245.1 - 0.0016 17.1 0.1 0.0025 16.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EME83245.1 - 0.024 14.5 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Dodecin PF07311.7 EME83245.1 - 0.075 13.0 0.4 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Dodecin CoA_binding_2 PF13380.1 EME83245.1 - 0.077 13.1 0.4 2.8 8.1 0.3 2.4 1 1 0 1 1 1 0 CoA binding domain adh_short PF00106.20 EME83245.1 - 0.16 11.8 0.4 0.47 10.3 0.2 1.9 2 1 0 2 2 2 0 short chain dehydrogenase BTB PF00651.26 EME83247.1 - 0.046 13.7 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain YlzJ PF14035.1 EME83247.1 - 0.058 13.4 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 YlzJ-like protein PSP1 PF04468.7 EME83249.1 - 7.9e-28 96.2 1.2 1.5e-27 95.4 0.8 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-C2H2 PF00096.21 EME83251.1 - 1.9e-10 40.4 15.9 0.00083 19.5 0.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME83251.1 - 5.7e-08 32.5 17.8 0.0059 16.8 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EME83251.1 - 0.016 15.1 4.0 0.84 9.6 2.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EME83251.1 - 0.038 13.7 1.3 0.038 13.7 0.9 2.0 2 0 0 2 2 2 0 BED zinc finger zf-Di19 PF05605.7 EME83251.1 - 0.045 13.8 8.7 0.66 10.1 0.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DGF-1_C PF11040.3 EME83251.1 - 0.083 12.7 0.7 0.19 11.6 0.5 1.6 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus AKAP2_C PF15304.1 EME83251.1 - 0.084 12.4 5.9 0.12 12.0 4.1 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus zf-C2H2_2 PF12756.2 EME83251.1 - 0.14 12.2 6.5 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EME83251.1 - 1.4 9.2 11.5 14 6.1 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain APC_CDC26 PF10471.4 EME83251.1 - 1.6 9.4 7.0 1.5 9.6 1.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Dor1 PF04124.7 EME83254.1 - 2.2e-52 177.5 3.6 2.4e-37 128.2 3.4 2.1 1 1 1 2 2 2 2 Dor1-like family Prok-TraM PF09228.5 EME83254.1 - 0.33 11.1 2.2 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM UQ_con PF00179.21 EME83255.1 - 4e-22 78.1 0.0 7.2e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EME83255.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 UEV domain DUF605 PF04652.11 EME83255.1 - 3.5 6.9 9.8 0.15 11.4 2.8 1.5 2 0 0 2 2 2 0 Vta1 like BTB PF00651.26 EME83256.1 - 5.8e-09 35.9 0.0 9.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF155 PF02582.9 EME83257.1 - 1.5e-59 200.8 0.0 5.3e-59 199.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Beta-lactamase PF00144.19 EME83258.1 - 4.4e-43 147.5 1.3 1.3e-42 146.0 0.9 1.6 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EME83258.1 - 0.21 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase 3-HAO PF06052.7 EME83259.1 - 5e-47 159.1 0.0 6.2e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EME83259.1 - 6.7e-07 28.7 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EME83259.1 - 0.0024 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EME83259.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF2528 PF10800.3 EME83259.1 - 0.1 12.9 0.2 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) Ribonuc_L-PSP PF01042.16 EME83260.1 - 2.2e-16 59.7 0.0 2.5e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_28 PF00295.12 EME83261.1 - 4.7e-107 357.7 17.8 5.5e-107 357.4 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EME83261.1 - 0.0028 17.4 36.6 0.32 10.7 22.2 3.5 1 1 1 2 2 2 2 Right handed beta helix region DUF2111 PF09884.4 EME83261.1 - 0.11 12.3 0.2 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) SIMPL PF04402.9 EME83262.1 - 4.1e-21 75.8 0.0 4.9e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) ABC_membrane_2 PF06472.10 EME83263.1 - 6.6e-95 317.4 0.1 1.1e-94 316.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME83263.1 - 1.9e-15 57.3 0.0 6.6e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 EME83263.1 - 0.00014 22.2 1.6 0.00056 20.2 1.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EME83263.1 - 0.0099 15.8 0.0 0.031 14.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ALIX_LYPXL_bnd PF13949.1 EME83263.1 - 0.01 14.8 0.4 0.021 13.8 0.3 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA_19 PF13245.1 EME83263.1 - 0.021 14.5 0.1 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EME83263.1 - 0.021 14.8 0.0 0.077 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EME83263.1 - 0.032 13.7 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 EME83263.1 - 0.075 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus THOC7 PF05615.8 EME83263.1 - 0.46 10.7 4.7 0.33 11.2 1.8 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 MRP-S28 PF10213.4 EME83264.1 - 2.8e-35 121.1 1.5 5.9e-35 120.1 1.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4078 PF13300.1 EME83264.1 - 0.12 12.5 2.7 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) Glyco_tran_28_C PF04101.11 EME83265.1 - 1.5e-18 67.0 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EME83265.1 - 0.00057 19.1 0.1 0.00078 18.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 AAA_12 PF13087.1 EME83266.1 - 4e-33 114.4 0.0 7e-33 113.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME83266.1 - 2.1e-25 89.6 0.1 5.7e-16 58.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EME83266.1 - 3.4e-13 49.1 0.0 5e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EME83266.1 - 1.1e-07 31.6 0.0 1.6e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EME83266.1 - 1.5e-06 27.9 0.0 0.19 11.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EME83266.1 - 9e-05 21.9 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EME83266.1 - 0.00026 20.6 0.0 0.0044 16.6 0.0 2.4 3 0 0 3 3 3 1 Helicase UvrD_C PF13361.1 EME83266.1 - 0.00075 19.0 0.0 0.084 12.3 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EME83266.1 - 0.0009 19.3 0.0 0.0043 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EME83266.1 - 0.0034 16.4 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EME83266.1 - 0.0044 17.0 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 EME83266.1 - 0.0054 16.5 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EME83266.1 - 0.0074 16.4 0.0 0.049 13.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EME83266.1 - 0.025 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 EME83266.1 - 0.028 13.1 0.0 4.7 5.7 0.0 2.1 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein DEAD PF00270.24 EME83266.1 - 0.031 13.7 0.0 0.073 12.5 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 EME83266.1 - 0.053 12.7 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EME83266.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME83266.1 - 0.16 12.8 0.1 0.4 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain IlvN PF07991.7 EME83267.1 - 9.7e-47 158.3 0.0 1.5e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EME83267.1 - 2.1e-44 150.9 0.0 3.7e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EME83267.1 - 0.027 14.8 0.1 0.087 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EME83267.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 EME83268.1 - 9.3e-05 22.2 1.5 0.00016 21.5 1.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EndIII_4Fe-2S PF10576.4 EME83268.1 - 1.1 9.5 8.1 5.6 7.3 0.3 2.5 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III AMOP PF03782.12 EME83269.1 - 0.062 13.2 0.6 0.072 13.0 0.4 1.3 1 0 0 1 1 1 0 AMOP domain Pkinase PF00069.20 EME83271.1 - 4.8e-70 235.6 0.0 5.8e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83271.1 - 3.1e-31 108.3 0.0 4.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME83271.1 - 0.02 14.6 0.7 0.066 12.9 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EME83271.1 - 0.087 11.8 0.0 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldedh PF00171.17 EME83272.1 - 3.1e-75 253.2 0.0 3.7e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRAPP PF04051.11 EME83275.1 - 8.1e-34 116.3 0.0 9.5e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EME83276.1 - 2e-56 185.9 12.3 5.9e-09 35.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EME83276.1 - 0.0019 17.7 0.2 0.38 10.1 0.0 2.5 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EME83276.1 - 0.0058 15.4 1.6 0.63 8.7 0.1 2.6 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EME83276.1 - 0.047 11.9 0.2 0.09 11.0 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain NicO PF03824.11 EME83277.1 - 0.027 13.7 0.3 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein HemY_N PF07219.8 EME83277.1 - 0.07 12.6 0.2 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Cmc1 PF08583.5 EME83278.1 - 3.4e-15 55.5 10.5 3.4e-15 55.5 7.3 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3323 PF11796.3 EME83278.1 - 0.52 9.6 3.4 0.72 9.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) CHCH PF06747.8 EME83278.1 - 2.1 8.3 10.3 13 5.7 7.1 2.1 1 1 0 1 1 1 0 CHCH domain YqzE PF14038.1 EME83278.1 - 2.3 8.0 5.3 5.6 6.7 3.7 1.7 1 0 0 1 1 1 0 YqzE-like protein ADH_N PF08240.7 EME83279.1 - 3.3e-33 113.7 0.2 5.6e-33 112.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83279.1 - 6.3e-25 87.2 0.4 9.4e-25 86.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EME83279.1 - 9.7e-05 22.9 0.1 0.00018 22.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME83279.1 - 0.0081 15.5 0.1 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UDPG_MGDP_dh_N PF03721.9 EME83279.1 - 0.017 14.5 0.3 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_26 PF13659.1 EME83279.1 - 0.099 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EME83279.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SSF PF00474.12 EME83280.1 - 9.6e-12 44.2 8.4 1.2e-11 43.9 5.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family O-antigen_lig PF13425.1 EME83280.1 - 0.025 14.5 1.4 0.025 14.5 1.0 2.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Synuclein PF01387.12 EME83280.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Synuclein TraW_N PF12477.3 EME83280.1 - 3.4 7.7 15.0 0.77 9.7 0.2 3.3 4 0 0 4 4 4 0 Sex factor F TraW protein N terminal DUF3784 PF12650.2 EME83280.1 - 6.1 6.8 12.5 5.3 7.0 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) ADH_N PF08240.7 EME83281.1 - 5.1e-26 90.5 1.0 1.1e-25 89.5 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83281.1 - 1.3e-09 37.6 0.0 3.5e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EME83281.1 - 5.3e-05 22.7 0.5 5.3e-05 22.7 0.4 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated FAD_binding_3 PF01494.14 EME83281.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain SRRM_C PF15230.1 EME83282.1 - 0.018 15.0 1.5 0.035 14.1 1.1 1.6 1 1 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus NAD_binding_6 PF08030.7 EME83283.1 - 3.6e-19 69.1 0.0 5.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME83283.1 - 6.1e-16 58.6 10.5 6.1e-16 58.6 7.3 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME83283.1 - 1.1e-11 44.4 0.0 2.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EME83283.1 - 0.0036 17.8 0.0 0.52 10.9 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GWT1 PF06423.7 EME83285.1 - 2.7e-40 137.6 0.0 7.4e-40 136.1 0.0 1.8 1 0 0 1 1 1 1 GWT1 Pkinase PF00069.20 EME83286.1 - 5.8e-13 48.5 0.0 7.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83286.1 - 1.9e-08 33.7 0.0 3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME83286.1 - 0.017 14.8 1.1 0.09 12.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cytochrom_C_2 PF01322.15 EME83286.1 - 0.66 10.5 4.4 1.4 9.4 3.0 1.5 1 1 0 1 1 1 0 Cytochrome C' SLT_L PF14718.1 EME83286.1 - 6.8 6.5 9.6 21 4.9 2.7 2.6 2 1 0 2 2 2 0 Soluble lytic murein transglycosylase L domain NmrA PF05368.8 EME83287.1 - 2.5e-47 161.0 0.3 3.4e-47 160.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME83287.1 - 5.5e-12 46.0 0.0 8.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME83287.1 - 2e-07 30.0 0.0 2.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EME83287.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EME83287.1 - 0.023 13.6 0.1 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.11 EME83287.1 - 0.028 14.9 0.1 0.06 13.8 0.1 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Epimerase PF01370.16 EME83287.1 - 0.032 13.6 0.0 0.067 12.6 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3311 PF11755.3 EME83288.1 - 0.027 14.0 0.9 1 8.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Arylsulfotran_2 PF14269.1 EME83289.1 - 3.4e-44 151.2 0.1 1e-43 149.6 0.2 1.7 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME83289.1 - 1.8e-10 39.9 0.1 3.1e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) CM2 PF03021.9 EME83290.1 - 0.2 11.2 3.8 1.4 8.4 0.4 2.2 1 1 1 2 2 2 0 Influenza C virus M2 protein GST_N_3 PF13417.1 EME83291.1 - 1.8e-10 40.8 0.1 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME83291.1 - 3.3e-09 36.5 0.1 6.4e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME83291.1 - 2.1e-07 30.7 0.0 3.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME83291.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME83291.1 - 0.095 12.8 0.0 0.43 10.7 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Bromodomain PF00439.20 EME83293.1 - 2.3e-23 81.9 0.1 4.5e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EME83293.1 - 6.1e-11 42.3 0.2 6.9e-10 38.9 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME83293.1 - 5.8e-10 39.0 0.1 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME83293.1 - 0.034 13.9 0.0 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein TPPK_C PF12555.3 EME83294.1 - 0.23 11.2 1.9 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Virul_fac_BrkB PF03631.10 EME83295.1 - 0.012 14.9 0.2 0.013 14.8 0.2 1.0 1 0 0 1 1 1 0 Virulence factor BrkB UPF0197 PF05251.7 EME83295.1 - 0.17 12.2 4.3 0.58 10.4 3.0 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Rad1 PF02144.11 EME83296.1 - 7.1e-77 257.8 0.4 8.1e-77 257.6 0.3 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 EHN PF06441.7 EME83297.1 - 7.2e-33 112.8 0.2 1.3e-32 112.0 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EME83297.1 - 8.8e-08 32.3 0.1 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME83297.1 - 4.2e-07 29.7 0.0 2.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 EME83298.1 - 3.7e-106 355.4 30.9 4.3e-106 355.1 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83298.1 - 7.2e-17 61.1 36.7 3.3e-13 49.0 6.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.18 EME83300.1 - 3.4e-43 143.5 95.1 1.7e-05 24.4 1.9 11.2 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_4 PF14392.1 EME83300.1 - 1.8e-06 27.4 71.6 0.096 12.3 0.2 10.9 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_2 PF13696.1 EME83300.1 - 0.00087 18.7 53.6 1.3 8.5 0.2 9.9 7 2 3 10 10 10 6 Zinc knuckle zf-CCHC_6 PF15288.1 EME83300.1 - 0.0061 16.1 0.2 0.0061 16.1 0.1 10.5 9 2 2 11 11 11 5 Zinc knuckle zf-CCHC_3 PF13917.1 EME83300.1 - 0.073 12.8 0.3 0.073 12.8 0.2 10.9 3 2 8 11 11 11 0 Zinc knuckle Chitin_synth_1 PF01644.12 EME83302.1 - 9.8e-81 269.3 0.4 1.4e-80 268.8 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EME83302.1 - 5.8e-31 106.0 0.1 1.2e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EME83302.1 - 2.4e-22 79.0 2.5 2.2e-17 62.6 0.0 3.0 3 1 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EME83302.1 - 6.8e-09 35.8 0.0 4.5e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME83302.1 - 2.4e-07 30.6 17.3 6.1e-06 26.0 12.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 LMWPc PF01451.16 EME83303.1 - 1.4e-27 96.7 0.0 1.8e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase AA_permease_2 PF13520.1 EME83304.1 - 2.6e-41 141.5 45.5 3.2e-41 141.2 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME83304.1 - 1.9e-29 102.3 39.3 2.6e-29 101.9 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 EME83305.1 - 5.8e-29 101.6 0.0 9.6e-28 97.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME83305.1 - 9.1e-08 32.0 0.0 7.6e-05 22.5 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME83305.1 - 1.2e-07 31.6 0.0 9.4e-07 28.7 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EME83305.1 - 1.3e-06 26.9 0.0 4.6e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EME83305.1 - 0.00022 21.3 0.0 0.0076 16.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EME83305.1 - 0.00027 20.8 0.1 0.7 9.7 0.2 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME83305.1 - 0.00044 19.2 0.0 0.023 13.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EME83305.1 - 0.023 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3734 PF12536.3 EME83305.1 - 0.1 12.7 0.2 8 6.6 0.1 2.4 2 0 0 2 2 2 0 Patatin phospholipase NAD_binding_7 PF13241.1 EME83305.1 - 0.13 12.4 0.0 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EME83305.1 - 0.95 8.3 3.5 2.3 7.0 0.8 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 EME83307.1 - 1.1e-28 99.9 44.9 1.5e-28 99.5 31.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME83307.1 - 2.2e-06 26.5 32.2 0.0031 16.1 3.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter APH PF01636.18 EME83308.1 - 6.6e-15 55.4 0.1 1.7e-14 54.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4551 PF15087.1 EME83309.1 - 0.14 10.5 9.2 0.19 10.0 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) C2 PF00168.25 EME83310.1 - 2.1e-67 222.9 4.1 2.6e-18 65.6 0.0 5.8 6 0 0 6 6 6 5 C2 domain NT-C2 PF10358.4 EME83310.1 - 0.031 13.7 0.5 1.4 8.3 0.0 3.4 4 0 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_11 PF13414.1 EME83311.1 - 6.5e-56 185.8 28.4 2e-16 59.3 1.5 6.4 5 1 0 6 6 6 5 TPR repeat TPR_1 PF00515.23 EME83311.1 - 4.3e-41 136.8 25.5 7e-07 28.5 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EME83311.1 - 7.6e-34 112.9 24.0 0.00018 21.1 0.5 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 EME83311.1 - 6.2e-20 71.3 18.0 0.0027 18.3 0.3 6.6 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 EME83311.1 - 1.1e-16 59.5 8.9 0.0059 16.7 0.2 8.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME83311.1 - 1.3e-16 60.3 14.1 3.1e-10 39.8 0.2 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EME83311.1 - 1.4e-16 58.9 12.8 0.00055 19.5 0.1 7.9 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME83311.1 - 1.7e-16 59.1 21.3 0.0049 17.3 0.1 9.4 6 3 5 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EME83311.1 - 6.4e-15 55.2 20.0 0.0022 18.2 0.1 6.7 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 EME83311.1 - 1.9e-10 40.4 6.0 0.00064 19.5 0.2 5.3 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME83311.1 - 2.7e-09 36.1 8.5 0.00028 20.4 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME83311.1 - 7.6e-09 35.4 14.5 0.66 10.5 0.0 8.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EME83311.1 - 0.00025 21.0 12.6 0.082 13.0 0.8 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EME83311.1 - 0.016 15.0 2.2 6.2 6.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME83311.1 - 0.045 13.6 0.0 0.045 13.6 0.0 5.0 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EME83311.1 - 0.13 12.4 0.0 0.13 12.4 0.0 5.5 6 2 0 6 6 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EME83311.1 - 0.56 10.4 13.3 7.3 6.8 0.7 4.6 5 0 0 5 5 5 0 Alkyl sulfatase dimerisation RPN7 PF10602.4 EME83311.1 - 1.2 8.5 7.6 2.1 7.7 0.0 4.3 4 2 2 6 6 6 0 26S proteasome subunit RPN7 Myb_DNA-bind_3 PF12776.2 EME83312.1 - 0.00079 20.0 3.3 0.0012 19.4 1.7 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME83312.1 - 0.008 16.2 0.2 0.008 16.2 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain ATP_bind_3 PF01171.15 EME83312.1 - 0.02 14.3 0.1 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Sigma70_r4_2 PF08281.7 EME83312.1 - 0.056 12.9 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Ribonuc_L-PSP PF01042.16 EME83313.1 - 2.7e-40 136.8 0.0 3.1e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3186 PF11382.3 EME83313.1 - 0.055 12.5 0.0 0.081 12.0 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3186) eRF1_1 PF03463.10 EME83314.1 - 6.2e-47 158.4 0.0 1.3e-46 157.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EME83314.1 - 1.2e-22 80.2 0.0 2.4e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EME83314.1 - 5e-22 78.6 0.0 9.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Aldo_ket_red PF00248.16 EME83315.1 - 8.3e-45 152.7 0.0 1.2e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Cellulase PF00150.13 EME83316.1 - 5.8e-14 51.9 7.1 4.2e-12 45.8 4.9 2.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GPI-anchored PF10342.4 EME83317.1 - 2.7e-23 82.2 2.2 2.7e-23 82.2 1.5 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PBP1_TM PF14812.1 EME83318.1 - 0.088 13.1 0.4 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 EME83318.1 - 0.099 11.9 1.0 0.15 11.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) La PF05383.12 EME83318.1 - 0.12 12.2 0.3 1.9 8.3 0.0 2.7 3 0 0 3 3 3 0 La domain ILVD_EDD PF00920.16 EME83319.1 - 4.6e-205 681.9 4.2 5.3e-205 681.7 2.9 1.0 1 0 0 1 1 1 1 Dehydratase family ER_lumen_recept PF00810.13 EME83320.1 - 4.8e-38 130.9 13.3 7.8e-38 130.2 9.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EME83320.1 - 0.031 13.8 10.5 0.05 13.1 0.2 3.2 4 0 0 4 4 4 0 PQ loop repeat IncA PF04156.9 EME83321.1 - 0.013 15.1 12.7 0.0077 15.8 6.9 1.9 2 0 0 2 2 2 0 IncA protein Cortex-I_coil PF09304.5 EME83321.1 - 0.092 12.7 9.9 0.23 11.4 6.9 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil Tropomyosin_1 PF12718.2 EME83321.1 - 0.33 10.7 16.6 0.84 9.4 11.5 1.6 1 1 0 1 1 1 0 Tropomyosin like Fzo_mitofusin PF04799.8 EME83321.1 - 0.46 9.8 2.2 0.86 8.9 1.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region HOOK PF05622.7 EME83321.1 - 0.63 7.7 10.2 0.91 7.2 7.1 1.1 1 0 0 1 1 1 0 HOOK protein GAS PF13851.1 EME83321.1 - 4.5 6.4 10.1 11 5.1 7.0 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EME83321.1 - 8.6 6.2 15.2 82 3.0 10.5 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_3 PF00933.16 EME83323.1 - 4.1e-22 78.5 0.0 5e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain SUN PF03856.8 EME83323.1 - 0.054 12.7 0.1 0.067 12.4 0.1 1.1 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Glyco_hydro_3 PF00933.16 EME83324.1 - 4.4e-81 272.1 0.0 6.2e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME83324.1 - 3.5e-48 164.1 0.1 6.7e-47 159.8 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME83324.1 - 3.1e-20 71.8 0.8 7.5e-20 70.6 0.2 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Sas10_Utp3 PF04000.10 EME83325.1 - 2e-05 24.6 0.1 4.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Tom22 PF04281.8 EME83325.1 - 0.14 11.6 2.0 0.33 10.4 1.4 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Acyl-CoA_dh_1 PF00441.19 EME83326.1 - 9.4e-28 97.2 1.0 1.5e-27 96.5 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME83326.1 - 5e-17 62.5 0.7 9.3e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME83326.1 - 8.7e-14 51.9 0.7 1.6e-13 51.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME83326.1 - 3.8e-11 42.3 0.0 9e-11 41.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glyco_hydro_43 PF04616.9 EME83327.1 - 1.1e-15 57.5 8.7 2.6e-15 56.2 5.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 ADH_N PF08240.7 EME83328.1 - 6.5e-28 96.6 1.4 1.1e-27 95.8 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83328.1 - 2.9e-14 52.7 0.0 5.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EME83328.1 - 0.0019 18.3 0.4 0.0038 17.2 0.1 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 EME83328.1 - 0.097 13.5 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Iso_dh PF00180.15 EME83329.1 - 5.6e-111 370.8 0.0 6.6e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acetyltransf_1 PF00583.19 EME83330.1 - 2e-05 24.5 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME83330.1 - 0.026 14.6 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_47 PF01532.15 EME83331.1 - 1.7e-119 399.4 0.0 1.9e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 EME83331.1 - 0.094 12.0 0.1 0.094 12.0 0.1 2.3 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 DUF3951 PF13131.1 EME83332.1 - 0.084 12.6 1.9 0.093 12.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF159 PF02586.9 EME83334.1 - 2e-58 197.3 0.1 3.1e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Amidase_6 PF12671.2 EME83334.1 - 0.066 13.2 0.1 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative amidase domain TPR_12 PF13424.1 EME83335.1 - 2.9e-08 33.5 9.9 0.02 14.8 1.2 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EME83335.1 - 1.4e-06 27.8 6.5 0.068 12.8 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EME83335.1 - 3e-06 26.7 8.6 0.16 11.9 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME83335.1 - 6.9e-05 22.2 6.0 0.074 12.6 0.5 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME83335.1 - 6.9e-05 23.1 8.3 0.34 11.6 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME83335.1 - 0.0017 18.0 5.5 1.7 8.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME83335.1 - 0.0029 17.2 6.6 4.5 7.2 0.2 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EME83335.1 - 0.024 14.7 1.3 0.27 11.4 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EME83335.1 - 0.06 13.7 5.4 0.26 11.6 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 EME83336.1 - 2.3e-26 92.8 0.2 2.9e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily G_glu_transpept PF01019.16 EME83337.1 - 1.5e-139 465.8 0.0 1.7e-139 465.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GFA PF04828.9 EME83338.1 - 7e-24 83.5 0.0 1.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 EME83338.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Tbf5 PF06331.7 EME83339.1 - 1.3e-25 88.9 0.8 1.5e-25 88.7 0.5 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF3783 PF12646.2 EME83339.1 - 0.019 14.7 0.1 0.046 13.4 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3783) RCC_reductase PF06405.6 EME83339.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) WBP-1 PF11669.3 EME83340.1 - 0.00059 19.8 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 WW domain-binding protein 1 Pox_LP_H2 PF03356.10 EME83340.1 - 0.044 13.4 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 Viral late protein H2 DUF1206 PF06724.6 EME83340.1 - 0.075 12.8 0.3 2.6 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Ni_hydr_CYTB PF01292.15 EME83340.1 - 0.09 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SKG6 PF08693.5 EME83340.1 - 0.098 11.9 2.8 0.21 10.9 1.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M56 PF05569.6 EME83340.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Pro-kuma_activ PF09286.6 EME83341.1 - 2.7e-34 118.2 0.0 4.6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME83341.1 - 5e-12 45.5 0.6 2.1e-11 43.5 0.1 2.1 2 0 0 2 2 2 1 Subtilase family Androgen_recep PF02166.11 EME83341.1 - 0.0018 17.1 0.5 0.015 14.2 0.0 2.1 1 1 0 2 2 2 1 Androgen receptor DUF1365 PF07103.6 EME83343.1 - 1.3e-42 145.6 0.0 1.9e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Glyoxalase_2 PF12681.2 EME83344.1 - 6e-07 30.0 0.1 1.8e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EME83344.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MARVEL PF01284.18 EME83345.1 - 1e-23 83.7 13.9 1.2e-23 83.5 9.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain SPRY PF00622.23 EME83346.1 - 2.7e-06 27.4 0.1 4.5e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Lactamase_B_3 PF13483.1 EME83347.1 - 0.00033 20.4 0.4 0.0009 18.9 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Response_reg PF00072.19 EME83348.1 - 1.3e-22 79.8 0.2 2.6e-22 78.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EME83348.1 - 1.5e-21 76.2 0.0 3.3e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EME83348.1 - 3.1e-11 43.5 0.0 2.8e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 EME83348.1 - 2.4e-05 24.2 3.9 3.6e-05 23.6 0.3 2.9 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EME83348.1 - 5.7e-05 23.6 0.0 0.00018 21.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS PF00989.19 EME83348.1 - 6.2e-05 22.7 0.0 0.0039 16.9 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.5 EME83348.1 - 0.00012 22.1 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 EME83348.1 - 0.00066 19.7 0.1 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.1 EME83348.1 - 0.0014 18.7 0.0 0.0046 17.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.1 EME83348.1 - 0.0071 16.1 0.0 0.025 14.4 0.0 2.0 1 0 0 1 1 1 1 PAS domain YgbA_NO PF11756.3 EME83349.1 - 0.11 12.5 0.4 0.11 12.5 0.3 2.0 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter Methyltransf_23 PF13489.1 EME83351.1 - 1.4e-15 57.3 0.0 2.1e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME83351.1 - 3.1e-09 37.2 0.0 8.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME83351.1 - 5.9e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME83351.1 - 0.00052 20.5 0.0 0.002 18.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME83351.1 - 0.0012 18.4 0.0 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EME83351.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EME83351.1 - 0.041 14.2 0.0 0.29 11.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EME83351.1 - 0.068 12.2 0.0 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FAD-oxidase_C PF02913.14 EME83353.1 - 1.3e-55 188.4 0.1 2.5e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EME83353.1 - 1e-36 125.4 0.0 1.9e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GATA PF00320.22 EME83354.1 - 8.1e-16 57.0 4.2 1.6e-15 56.1 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EME83354.1 - 5.3e-13 48.8 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EME83354.1 - 3e-10 39.8 0.0 6.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EME83354.1 - 2e-09 37.7 0.0 5.7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EME83354.1 - 5.8e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EME83354.1 - 8.7e-06 25.6 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EME83354.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF4428 PF14471.1 EME83354.1 - 0.21 11.3 3.8 0.17 11.6 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) RRN7 PF11781.3 EME83354.1 - 1.7 8.1 4.9 8.7 5.9 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 AAA_23 PF13476.1 EME83356.1 - 9e-24 84.9 0.0 9e-24 84.9 0.0 7.3 1 1 3 4 4 4 1 AAA domain SbcCD_C PF13558.1 EME83356.1 - 7.2e-11 41.8 0.0 3.3e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EME83356.1 - 1.2e-09 37.7 0.1 1.2e-09 37.7 0.1 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME83356.1 - 1.3e-08 35.2 8.0 0.00066 19.7 0.0 4.2 4 1 1 5 5 5 2 AAA domain AAA_13 PF13166.1 EME83356.1 - 3.4e-06 25.8 0.2 0.00098 17.7 0.0 7.3 2 1 4 7 7 7 2 AAA domain AAA_29 PF13555.1 EME83356.1 - 8.3e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.16 EME83356.1 - 0.0016 18.0 22.0 0.0016 18.0 15.2 6.2 1 1 5 6 6 6 1 Intermediate filament protein AAA_15 PF13175.1 EME83356.1 - 0.02 13.9 0.0 0.02 13.9 0.0 5.3 3 2 1 4 4 4 0 AAA ATPase domain ABC_tran PF00005.22 EME83356.1 - 0.027 14.7 0.0 0.027 14.7 0.0 6.1 3 2 0 3 3 3 0 ABC transporter AAA_19 PF13245.1 EME83356.1 - 0.039 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Cellulase PF00150.13 EME83357.1 - 1.1e-17 64.2 1.0 1.1e-17 64.2 0.7 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 EME83358.1 - 1.4e-18 67.3 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME83358.1 - 2.6e-15 56.8 0.0 3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acyl-CoA_dh_1 PF00441.19 EME83360.1 - 1.7e-32 112.6 1.0 2.5e-32 112.0 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EME83360.1 - 1.5e-20 72.7 0.1 3.3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EME83360.1 - 1.1e-17 63.2 0.4 4.2e-17 61.4 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME83360.1 - 1e-07 32.5 0.2 2.6e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME83360.1 - 0.00034 20.8 0.0 0.00089 19.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-U1 PF06220.7 EME83361.1 - 6.4e-22 76.8 3.4 8.6e-22 76.4 2.3 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EME83361.1 - 0.023 14.8 3.6 0.048 13.8 2.5 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Rav1p_C PF12234.3 EME83362.1 - 5.1e-103 345.3 0.0 1.1e-102 344.3 0.0 1.5 1 1 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EME83362.1 - 3.4e-07 29.8 0.0 0.0015 18.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Pyr_redox_2 PF07992.9 EME83363.1 - 4e-25 88.8 7.6 4.7e-24 85.3 5.2 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME83363.1 - 1.2e-15 57.6 1.9 5.5e-15 55.5 1.3 2.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EME83363.1 - 1.9e-13 49.7 0.0 6.7e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EME83363.1 - 1.9e-09 37.8 0.4 1.8e-05 24.9 0.0 3.3 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME83363.1 - 0.0016 17.4 0.3 0.11 11.3 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 EME83363.1 - 0.0041 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 EME83363.1 - 0.027 14.2 0.1 5.7 6.6 0.0 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EME83363.1 - 0.07 11.7 0.2 0.17 10.4 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase EPSP_synthase PF00275.15 EME83364.1 - 2e-118 395.5 0.0 3e-118 394.8 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EME83364.1 - 1.2e-98 329.1 0.0 2.1e-98 328.4 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EME83364.1 - 4.7e-58 196.4 0.0 7.9e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EME83364.1 - 2e-37 128.5 0.0 1.1e-36 126.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EME83364.1 - 6.4e-23 80.6 0.0 2e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EME83364.1 - 1.3e-09 38.2 0.0 6.7e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EME83364.1 - 1.9e-07 30.6 0.0 4.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EME83364.1 - 7e-06 26.8 0.1 3.9e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME83364.1 - 0.071 13.4 0.1 3.7 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EME83364.1 - 0.24 11.2 0.0 0.87 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_S2 PF00318.15 EME83365.1 - 2.5e-43 147.7 0.0 2.5e-23 82.4 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EME83366.1 - 5.4e-15 54.9 0.1 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 COesterase PF00135.23 EME83367.1 - 4.3e-99 332.6 0.0 5.7e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME83367.1 - 4.5e-10 39.4 0.2 4.5e-08 32.9 0.5 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME83367.1 - 0.00069 18.9 0.3 0.0036 16.5 0.2 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF416 PF04222.7 EME83369.1 - 0.039 13.0 0.5 0.039 13.0 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF416) FliG_N PF14842.1 EME83369.1 - 0.085 12.9 0.1 0.26 11.4 0.1 1.8 1 1 0 1 1 1 0 FliG N-terminal domain Gal4_dimer PF03902.8 EME83369.1 - 0.12 12.2 1.0 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain FKBP_N PF01346.13 EME83369.1 - 3.2 7.7 5.4 5.7 7.0 1.0 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase RRP7 PF12923.2 EME83370.1 - 4.1e-34 117.4 13.1 7.7e-34 116.5 9.1 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 EME83370.1 - 0.0012 18.8 0.0 0.049 13.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME83370.1 - 0.0015 18.1 0.0 0.55 9.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRI12 PF06609.8 EME83371.1 - 9.9e-50 169.3 20.7 1.2e-49 169.0 14.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME83371.1 - 1.4e-16 60.1 50.2 4.7e-16 58.4 32.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily NPR2 PF06218.6 EME83372.1 - 6.9e-102 341.3 0.0 4.4e-101 338.6 0.0 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Afi1 PF07792.7 EME83372.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3638 PF12340.3 EME83378.1 - 6.1e-93 310.0 0.0 1.1e-92 309.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EME83378.1 - 2.6e-13 48.8 1.8 5.4e-13 47.8 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) CENP-F_leu_zip PF10473.4 EME83381.1 - 0.003 17.4 2.8 0.0036 17.1 1.9 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.13 EME83381.1 - 0.0047 16.8 3.4 0.2 11.6 0.3 2.4 2 0 0 2 2 2 1 TSC-22/dip/bun family DivIC PF04977.10 EME83381.1 - 0.065 12.7 7.3 0.84 9.1 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EME83381.1 - 0.071 12.9 4.8 2.9 7.7 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Phasin PF05597.6 EME83381.1 - 0.079 12.7 1.1 0.096 12.4 0.8 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Pox_A_type_inc PF04508.7 EME83381.1 - 0.12 12.2 0.3 3.7 7.5 0.0 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4570 PF15134.1 EME83381.1 - 0.13 12.0 1.3 0.2 11.4 0.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) Phage_GP20 PF06810.6 EME83381.1 - 0.15 11.4 6.4 0.21 11.0 1.0 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 Jnk-SapK_ap_N PF09744.4 EME83381.1 - 0.2 11.6 3.4 0.46 10.4 2.3 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 End3 PF12761.2 EME83381.1 - 0.22 11.1 2.6 0.28 10.7 1.8 1.2 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Seryl_tRNA_N PF02403.17 EME83381.1 - 0.24 11.4 5.6 3.4 7.7 0.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 EME83381.1 - 0.26 11.4 3.3 0.6 10.3 2.3 1.6 1 1 0 1 1 1 0 Syntaxin DivIVA PF05103.8 EME83381.1 - 0.35 10.9 3.6 0.88 9.6 2.5 1.6 1 1 0 1 1 1 0 DivIVA protein IncA PF04156.9 EME83381.1 - 0.78 9.2 4.7 2.5 7.6 3.3 1.7 1 1 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EME83381.1 - 0.82 9.5 3.8 2.4 8.0 0.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 EME83381.1 - 3 7.8 5.5 17 5.4 0.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor LigD_N PF13298.1 EME83383.1 - 7.3e-23 80.6 0.2 1.7e-22 79.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase Ligase (LigD) zf-Tim10_DDP PF02953.10 EME83384.1 - 7.6e-25 85.9 1.0 8.8e-25 85.7 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 EME83384.1 - 0.06 12.9 1.4 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Abi PF02517.11 EME83385.1 - 0.23 11.5 5.6 0.37 10.9 3.9 1.2 1 0 0 1 1 1 0 CAAX protease self-immunity FAD_binding_8 PF08022.7 EME83386.1 - 6.2e-23 80.6 0.0 1.5e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME83386.1 - 1.6e-22 80.0 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME83386.1 - 2.4e-16 59.9 6.8 2.4e-16 59.9 4.7 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EME83386.1 - 0.00036 20.5 0.0 0.00092 19.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Amidohydro_2 PF04909.9 EME83387.1 - 2.5e-15 56.7 0.1 4.3e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase adh_short_C2 PF13561.1 EME83388.1 - 4.3e-28 98.7 0.0 5e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME83388.1 - 2.8e-26 92.4 0.3 3.6e-26 92.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME83388.1 - 1.6e-10 40.9 0.1 2.4e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 KR domain DEAD PF00270.24 EME83389.1 - 3.4e-28 98.2 0.0 5.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME83389.1 - 4.9e-23 80.7 0.1 2.4e-22 78.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME83389.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EME83389.1 - 0.022 13.1 0.0 2.2 6.5 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1253) ATP-synt_G PF04718.10 EME83390.1 - 4e-25 88.4 0.4 1.9e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.8 EME83390.1 - 0.054 13.8 3.8 0.33 11.3 1.6 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_tranf_2_3 PF13641.1 EME83393.1 - 4.5e-23 82.2 0.1 6.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EME83393.1 - 1.1e-09 37.8 0.1 4e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME83393.1 - 1.5e-08 34.4 0.0 3.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EME83393.1 - 0.026 12.9 1.1 0.058 11.7 0.6 1.8 1 1 0 1 1 1 0 Chitin synthase DHDPS PF00701.17 EME83394.1 - 4.1e-28 97.8 0.0 5.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FolB PF02152.13 EME83395.1 - 1.8e-13 50.6 0.0 8.3e-08 32.3 0.1 3.1 2 1 0 2 2 2 2 Dihydroneopterin aldolase Glyco_hydro_76 PF03663.9 EME83396.1 - 1.2e-87 294.7 7.6 1.4e-87 294.5 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Dynein_light PF01221.13 EME83399.1 - 9.8e-41 137.6 2.3 1.2e-40 137.4 1.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 EME83400.1 - 1.4e-70 232.8 0.8 9.8e-19 66.7 0.0 5.8 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83400.1 - 4.8e-60 199.4 0.1 1e-16 60.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME83400.1 - 6.7e-37 125.1 0.0 1.4e-07 31.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME83400.1 - 2.8e-06 26.9 1.7 0.13 12.0 0.0 5.4 5 2 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 EME83400.1 - 4.1e-06 26.4 0.0 0.051 13.3 0.0 3.5 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EME83400.1 - 0.002 17.8 0.0 0.56 9.9 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif TEA PF01285.13 EME83401.1 - 7.6e-28 97.8 0.3 8.6e-28 97.6 0.2 1.0 1 0 0 1 1 1 1 TEA/ATTS domain family Cpn60_TCP1 PF00118.19 EME83402.1 - 5.1e-163 543.1 0.7 5.8e-163 542.9 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAM_LAG1_CLN8 PF03798.11 EME83403.1 - 1.3e-43 148.8 13.3 2e-43 148.2 9.2 1.3 1 0 0 1 1 1 1 TLC domain RICTOR_phospho PF14665.1 EME83403.1 - 0.018 15.0 0.3 0.035 14.2 0.2 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Rz1 PF06085.6 EME83403.1 - 0.69 9.3 3.7 1.4 8.4 2.6 1.4 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor PKD PF00801.15 EME83406.1 - 0.02 14.6 0.7 0.054 13.2 0.0 2.0 3 0 0 3 3 3 0 PKD domain Acyl-CoA_dh_1 PF00441.19 EME83407.1 - 1.8e-30 106.0 1.0 3.3e-30 105.1 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME83407.1 - 9.2e-19 68.0 0.5 1.8e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EME83407.1 - 9.6e-19 66.6 0.1 2.1e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EME83407.1 - 3.9e-16 59.5 1.6 1.5e-15 57.6 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Afi1 PF07792.7 EME83408.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF936 PF06075.7 EME83409.1 - 1.4 7.7 18.5 1.9 7.2 12.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DOMON PF03351.12 EME83410.1 - 9.6e-05 22.3 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EME83410.1 - 0.00045 19.7 4.8 0.00086 18.8 3.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) DUF1181 PF06680.6 EME83410.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) DUF2231 PF09990.4 EME83410.1 - 0.12 12.6 4.4 0.11 12.8 1.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Sugar_tr PF00083.19 EME83411.1 - 1.1e-08 34.1 2.6 1.3e-08 33.8 1.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PHO4 PF01384.15 EME83411.1 - 0.051 12.2 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family SBF PF01758.11 EME83412.1 - 3.9e-48 163.3 4.9 3.9e-48 163.3 3.4 2.6 2 1 1 3 3 3 1 Sodium Bile acid symporter family zf-DHHC PF01529.15 EME83412.1 - 0.15 11.4 2.9 0.42 9.9 2.0 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase PIG-P PF08510.7 EME83412.1 - 0.31 10.6 4.3 2.1 8.0 0.2 3.0 2 1 0 2 2 2 0 PIG-P Pyr_redox_3 PF13738.1 EME83413.1 - 7.9e-20 71.7 0.0 2.7e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME83413.1 - 3.1e-12 45.4 0.1 4.2e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME83413.1 - 9.4e-11 41.5 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME83413.1 - 7e-07 28.4 0.0 6.8e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME83413.1 - 0.0016 18.3 0.0 0.082 12.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME83413.1 - 0.0039 16.1 0.0 0.072 11.9 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EME83413.1 - 0.016 15.0 0.0 0.69 9.6 0.0 3.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding Spc97_Spc98 PF04130.8 EME83414.1 - 2.2e-117 392.6 0.0 5.2e-117 391.4 0.0 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Aft1_HRA PF11786.3 EME83415.1 - 4.3e-29 100.5 9.8 4.3e-29 100.5 6.8 2.6 1 1 1 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EME83415.1 - 4e-15 56.6 10.8 4e-15 56.6 7.5 3.4 2 1 1 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 EME83415.1 - 8.4e-14 51.2 3.4 1.5e-13 50.4 2.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EME83415.1 - 9.7e-07 29.2 6.7 9.7e-07 29.2 4.7 4.4 3 1 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EME83415.1 - 3e-06 26.9 5.8 5.3e-06 26.1 4.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME83415.1 - 0.0014 18.8 2.5 0.0034 17.6 1.7 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor Nnf1 PF03980.9 EME83415.1 - 0.091 12.7 1.2 0.16 11.9 0.8 1.4 1 0 0 1 1 1 0 Nnf1 DUF1014 PF06244.7 EME83416.1 - 1.2e-21 77.2 11.8 2.8e-21 75.9 8.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Penicil_amidase PF01804.13 EME83416.1 - 0.19 10.7 6.0 0.2 10.6 4.1 1.1 1 0 0 1 1 1 0 Penicillin amidase HRDC PF00570.18 EME83417.1 - 0.024 14.3 0.8 0.32 10.7 0.2 2.2 2 0 0 2 2 2 0 HRDC domain Patatin PF01734.17 EME83418.1 - 5.3e-19 68.9 0.2 1.2e-18 67.7 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.18 EME83418.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EME83418.1 - 0.021 14.5 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EME83418.1 - 0.099 12.9 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 EME83418.1 - 0.35 10.0 0.0 0.67 9.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family zf-C3HC4_4 PF15227.1 EME83418.1 - 9.6 6.1 23.2 0.023 14.5 3.1 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING ADH_zinc_N PF00107.21 EME83420.1 - 3.4e-17 62.2 0.0 5.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME83420.1 - 9.1e-14 52.4 0.1 2.7e-13 50.9 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME83420.1 - 1.6e-10 40.6 0.1 8.2e-08 31.9 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain TRP PF06011.7 EME83421.1 - 1.8e-157 524.4 29.3 2.2e-157 524.1 20.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EME83421.1 - 3.2e-42 143.9 1.9 5.2e-42 143.2 1.3 1.3 1 0 0 1 1 1 1 ML-like domain DUF843 PF05814.6 EME83421.1 - 0.8 9.5 0.0 0.8 9.5 0.0 4.1 5 0 0 5 5 5 0 Baculovirus protein of unknown function (DUF843) DUF2373 PF10180.4 EME83422.1 - 4.4e-24 83.7 0.4 8e-24 82.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Peptidase_M9_N PF08453.5 EME83422.1 - 0.016 14.5 0.1 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal CDC45 PF02724.9 EME83422.1 - 3.1 5.7 18.0 0.82 7.6 4.9 2.2 2 0 0 2 2 2 0 CDC45-like protein Vfa1 PF08432.5 EME83422.1 - 3.2 7.7 22.6 6.2 6.8 3.9 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Proteasome PF00227.21 EME83423.1 - 2.5e-49 167.1 0.1 3.4e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME83423.1 - 3.9e-12 45.2 0.2 6.5e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PgpA PF04608.8 EME83423.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A Not3 PF04065.10 EME83425.1 - 3.5e-99 330.8 27.1 5.1e-99 330.2 18.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EME83425.1 - 8.2e-43 145.5 10.8 1.8e-42 144.3 7.5 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EME83425.1 - 0.0076 15.7 3.5 0.019 14.5 2.4 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EME83425.1 - 0.65 9.9 11.1 0.63 10.0 1.0 3.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 EME83425.1 - 0.85 9.8 17.9 0.062 13.4 4.7 3.2 1 1 2 3 3 3 0 Syntaxin Tyr_Deacylase PF02580.11 EME83426.1 - 1.1e-48 164.8 0.1 1.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase ADH_N PF08240.7 EME83427.1 - 7.1e-25 86.8 0.7 1.2e-24 86.1 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83427.1 - 1.5e-15 56.8 0.0 2.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME83427.1 - 0.00013 21.1 0.1 0.00022 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME83427.1 - 0.0037 16.8 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EME83427.1 - 0.025 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MAF_flag10 PF01973.13 EME83427.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 Mmp37 PF09139.6 EME83428.1 - 4.8e-124 413.6 0.0 6.9e-124 413.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Neur_chan_memb PF02932.11 EME83428.1 - 5.3 6.8 5.8 5.1 6.9 0.7 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hex_IIIa PF02455.11 EME83428.1 - 9.2 4.8 10.5 0.4 9.3 2.5 1.9 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) BIR PF00653.16 EME83429.1 - 4.9e-41 138.9 5.3 7.4e-21 74.3 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Coa1 PF08695.5 EME83429.1 - 0.0019 17.6 0.2 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPT PF03151.11 EME83430.1 - 5.9e-24 84.4 13.7 5.9e-24 84.4 9.5 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME83430.1 - 7.6e-14 51.3 23.6 1.2e-13 50.6 16.4 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME83430.1 - 0.06 13.3 37.5 0.028 14.4 7.8 3.1 2 2 1 3 3 3 0 EamA-like transporter family ABC2_membrane PF01061.19 EME83431.1 - 3e-91 304.2 60.1 1.9e-50 170.9 15.1 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EME83431.1 - 1.7e-34 119.0 0.0 6.6e-17 62.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EME83431.1 - 4.5e-30 103.3 8.0 6e-27 93.3 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EME83431.1 - 8.1e-11 41.8 0.0 3.4e-10 39.8 0.0 2.2 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EME83431.1 - 1.1e-05 24.7 0.0 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EME83431.1 - 3.1e-05 24.0 0.2 0.02 14.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME83431.1 - 6.6e-05 22.4 0.6 0.0084 15.5 0.1 3.4 2 2 0 2 2 2 1 AAA domain cobW PF02492.14 EME83431.1 - 0.00022 20.7 0.2 0.0015 18.0 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 EME83431.1 - 0.00033 19.7 38.5 0.00062 18.8 11.4 2.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.1 EME83431.1 - 0.00038 20.3 0.0 0.015 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME83431.1 - 0.00043 20.3 5.1 0.018 15.0 0.2 3.0 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EME83431.1 - 0.00044 20.3 0.5 0.13 12.3 0.1 3.3 2 2 1 3 3 3 1 AAA domain AAA_28 PF13521.1 EME83431.1 - 0.00057 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME83431.1 - 0.0015 18.0 0.2 0.14 11.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EME83431.1 - 0.0029 17.5 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 EME83431.1 - 0.0045 16.6 0.7 0.076 12.6 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EME83431.1 - 0.0045 17.2 0.0 0.051 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME83431.1 - 0.0046 17.7 0.1 0.065 14.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EME83431.1 - 0.0056 16.1 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family SMC_N PF02463.14 EME83431.1 - 0.011 14.9 0.1 0.11 11.7 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain GBP PF02263.14 EME83431.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Septin PF00735.13 EME83431.1 - 0.038 12.9 0.5 0.29 10.1 0.1 2.3 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 EME83431.1 - 0.05 13.4 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.7 EME83431.1 - 0.069 12.8 0.6 0.29 10.7 0.2 2.1 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EME83431.1 - 0.071 13.6 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EME83431.1 - 0.11 11.4 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EME83431.1 - 0.11 11.2 0.3 13 4.5 0.1 3.0 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 EME83431.1 - 0.16 11.4 0.3 0.44 10.0 0.2 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 2-Hacid_dh_C PF02826.14 EME83432.1 - 3.6e-50 169.5 0.0 4.8e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME83432.1 - 1.2e-23 82.9 0.0 1.5e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME83432.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME83432.1 - 0.032 14.6 0.1 0.11 12.8 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EME83432.1 - 0.14 12.7 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Gly_kinase PF02595.10 EME83435.1 - 2.6e-110 368.7 8.0 3.1e-110 368.4 5.6 1.0 1 0 0 1 1 1 1 Glycerate kinase family NAD_binding_10 PF13460.1 EME83435.1 - 0.0071 16.3 0.0 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding DEAD PF00270.24 EME83436.1 - 4.4e-34 117.4 0.0 2.9e-32 111.4 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME83436.1 - 1.2e-21 76.3 0.0 4.2e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EME83436.1 - 1e-14 53.7 0.0 2.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EME83436.1 - 0.00012 21.9 0.0 0.00042 20.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EME83436.1 - 0.039 14.1 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME83436.1 - 0.066 12.9 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Flavi_DEAD PF07652.9 EME83436.1 - 0.12 12.0 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain vATP-synt_AC39 PF01992.11 EME83437.1 - 6.2e-113 377.3 0.0 7e-113 377.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF423 PF04241.10 EME83437.1 - 0.085 12.7 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Nol1_Nop2_Fmu PF01189.12 EME83440.1 - 2.8e-46 158.1 0.0 1.3e-21 77.2 0.0 3.4 2 1 1 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EME83440.1 - 0.0041 17.1 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME83440.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Baculo_11_kDa PF06143.6 EME83441.1 - 0.066 12.5 0.1 0.2 11.0 0.1 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Fungal_trans PF04082.13 EME83442.1 - 2.1e-25 89.1 0.0 5.9e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME83442.1 - 1.3e-08 34.5 13.6 2.1e-08 33.9 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME83443.1 - 1.2e-27 96.6 29.3 4e-23 81.6 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME83443.1 - 3.3e-09 35.8 4.8 3.3e-09 35.8 3.3 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter Spore_YhaL PF14147.1 EME83443.1 - 0.09 12.2 0.6 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL UQ_con PF00179.21 EME83445.1 - 2.2e-11 43.3 0.1 3.6e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME83445.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EME83448.1 - 2.2e-95 318.6 1.9 3e-95 318.1 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME83448.1 - 2.6e-37 126.9 1.3 2.6e-37 126.9 0.9 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME83448.1 - 9.1e-05 22.0 1.1 0.00022 20.7 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EME83448.1 - 0.002 17.7 0.1 0.1 12.2 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.14 EME83448.1 - 0.038 13.2 0.1 0.094 11.9 0.0 1.6 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Kinesin PF00225.18 EME83449.1 - 3.9e-114 380.8 0.3 3.9e-114 380.8 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain XkdW PF09636.5 EME83449.1 - 8.4 6.3 17.9 1.1 9.2 1.3 3.7 3 1 0 3 3 3 0 XkdW protein tRNA-synt_2b PF00587.20 EME83450.1 - 6.5e-24 84.4 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EME83450.1 - 9.5e-16 57.7 2.9 9.5e-16 57.7 2.0 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EME83450.1 - 0.0081 15.7 0.5 0.015 14.8 0.4 1.4 1 0 0 1 1 1 1 IncA protein Synaptobrevin PF00957.16 EME83450.1 - 0.13 11.8 0.6 0.36 10.4 0.4 1.7 1 0 0 1 1 1 0 Synaptobrevin DivIC PF04977.10 EME83450.1 - 1.1 8.7 4.9 11 5.5 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Pyr_redox_3 PF13738.1 EME83451.1 - 1e-07 32.2 0.0 1e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME83451.1 - 8e-06 24.9 0.1 8.8e-06 24.8 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EME83451.1 - 0.00022 19.5 0.0 0.00025 19.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EME83451.1 - 0.00092 19.0 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding dsrm PF00035.20 EME83452.1 - 0.00013 22.4 0.0 0.00055 20.4 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Pkinase PF00069.20 EME83453.1 - 1.8e-17 63.3 0.0 7.7e-17 61.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83453.1 - 9.3e-10 38.0 0.0 2.9e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME83454.1 - 7.7e-10 38.3 0.0 1.4e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain SAPS PF04499.10 EME83454.1 - 0.0025 16.5 1.5 0.0028 16.3 1.1 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Nop14 PF04147.7 EME83454.1 - 0.023 12.6 45.7 0.031 12.2 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EME83454.1 - 0.2 9.6 31.5 0.3 9.0 21.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Adaptin_binding PF10199.4 EME83454.1 - 0.25 11.6 28.7 0.11 12.7 17.6 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CENP-T PF15511.1 EME83454.1 - 0.34 10.0 35.0 0.51 9.5 24.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 EME83454.1 - 0.55 9.6 11.5 0.95 8.8 7.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 EME83454.1 - 8.6 5.3 37.6 14 4.6 26.1 1.4 1 0 0 1 1 1 0 BUD22 Het-C PF07217.6 EME83455.1 - 5.4e-261 867.0 0.0 6.2e-261 866.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Bacteriocin_IIc PF10439.4 EME83455.1 - 0.019 15.0 9.7 0.043 13.9 6.7 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Zn_dep_PLPC PF00882.13 EME83455.1 - 0.039 13.6 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Zinc dependent phospholipase C TraT PF05818.7 EME83455.1 - 1.1 8.6 4.1 2.3 7.5 2.8 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 EME83455.1 - 1.8 8.2 5.9 3.3 7.3 4.1 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PRiA4_ORF3 PF07929.6 EME83456.1 - 6.3e-29 100.6 0.2 4.4e-28 97.8 0.2 1.9 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF4051 PF13260.1 EME83458.1 - 0.064 12.6 1.2 0.15 11.3 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) RicinB_lectin_2 PF14200.1 EME83460.1 - 4.9e-07 30.0 0.4 5.3e-06 26.7 0.0 2.4 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Borrelia_P83 PF05262.6 EME83460.1 - 0.0045 15.3 12.7 0.0049 15.1 8.8 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein HAUS6_N PF14661.1 EME83460.1 - 0.033 13.5 14.4 0.046 13.0 10.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.1 EME83460.1 - 0.24 10.2 15.0 0.38 9.6 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HemX PF04375.9 EME83460.1 - 0.29 9.7 13.0 0.4 9.2 9.0 1.2 1 0 0 1 1 1 0 HemX PA26 PF04636.8 EME83460.1 - 0.44 9.1 5.1 0.54 8.8 3.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Exonuc_VII_L PF02601.10 EME83460.1 - 0.5 9.5 8.6 0.6 9.2 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 EME83460.1 - 0.68 7.7 14.4 0.96 7.2 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.12 EME83460.1 - 1.2 7.8 4.5 1.5 7.5 3.1 1.1 1 0 0 1 1 1 0 Presenilin DUF3138 PF11336.3 EME83460.1 - 1.3 7.1 6.6 1.7 6.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_S64 PF08192.6 EME83460.1 - 2.2 6.5 9.0 3 6.0 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 IncA PF04156.9 EME83460.1 - 2.3 7.7 26.2 3.1 7.3 18.2 1.1 1 0 0 1 1 1 0 IncA protein DDHD PF02862.12 EME83460.1 - 4.8 6.8 10.6 7.1 6.3 7.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF2458 PF10454.4 EME83460.1 - 6 6.7 18.1 9.4 6.1 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF3584 PF12128.3 EME83460.1 - 7 3.8 25.5 8.5 3.5 17.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF342 PF03961.8 EME83460.1 - 7.8 4.7 17.0 10 4.3 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HSP70 PF00012.15 EME83460.1 - 8.9 4.0 16.6 11 3.8 11.5 1.0 1 0 0 1 1 1 0 Hsp70 protein COesterase PF00135.23 EME83462.1 - 2.4e-70 237.7 0.0 3.1e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME83462.1 - 0.0044 16.6 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold RRM_1 PF00076.17 EME83464.1 - 1.2e-43 146.6 1.2 3.7e-12 45.6 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83464.1 - 1.4e-39 133.9 2.0 2.2e-10 40.3 0.0 5.1 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME83464.1 - 6.9e-20 70.6 0.0 1.2e-07 31.4 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME83464.1 - 5.8e-10 38.7 0.0 0.0054 16.4 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EME83464.1 - 0.087 12.2 0.1 0.33 10.4 0.1 2.0 1 0 0 1 1 1 0 Lsm interaction motif Cytochrom_C PF00034.16 EME83464.1 - 0.79 10.5 4.8 1.1 10.1 0.0 3.6 4 0 0 4 4 4 0 Cytochrome c Ribosomal_L22 PF00237.14 EME83465.1 - 1.8e-18 66.4 0.1 6.6e-09 35.6 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e Git3 PF11710.3 EME83467.1 - 3e-12 46.5 6.9 1e-10 41.5 1.9 2.4 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EME83467.1 - 3.1e-10 39.4 1.8 4.2e-06 25.8 0.4 2.2 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3_C PF11970.3 EME83467.1 - 0.00011 21.9 0.1 0.00011 21.9 0.1 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term CbiQ PF02361.11 EME83467.1 - 0.018 14.6 0.2 0.059 12.9 0.1 1.8 1 1 0 1 1 1 0 Cobalt transport protein DUF1237 PF06824.6 EME83469.1 - 5.3e-156 519.4 0.1 6.3e-156 519.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) DUF1009 PF06230.6 EME83471.1 - 0.022 14.1 0.3 0.03 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) NAD_kinase PF01513.16 EME83471.1 - 0.055 12.2 0.1 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 ATP-NAD kinase IBN_N PF03810.14 EME83472.1 - 1e-13 51.0 0.6 2.5e-12 46.5 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EME83472.1 - 0.0003 20.7 0.7 0.0094 15.8 0.1 3.4 2 1 1 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EME83472.1 - 0.016 13.5 0.3 1.8 6.7 0.1 2.4 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus Ribosomal_L34e PF01199.13 EME83473.1 - 2e-36 124.0 4.5 2.9e-36 123.5 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EME83473.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) zf-ribbon_3 PF13248.1 EME83473.1 - 0.11 11.7 1.4 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PROCN PF08083.6 EME83474.1 - 8.5e-223 739.1 6.9 1.5e-222 738.3 4.8 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EME83474.1 - 2.2e-126 419.8 1.7 3.8e-126 419.0 1.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EME83474.1 - 1e-93 311.0 1.6 2.1e-93 309.9 1.1 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EME83474.1 - 2e-76 254.8 2.4 2e-76 254.8 1.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EME83474.1 - 1.6e-66 222.0 0.1 3.2e-66 221.0 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EME83474.1 - 1.7e-44 149.6 0.4 4.2e-44 148.3 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EME83474.1 - 1.1e-41 141.4 0.1 3.7e-41 139.7 0.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF498 PF04430.9 EME83475.1 - 2.5e-26 91.3 0.0 3.1e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) fn3 PF00041.16 EME83477.1 - 3.4e-10 39.9 0.8 0.00052 20.0 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EME83477.1 - 2e-09 37.8 0.2 7.8e-09 35.9 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME83477.1 - 0.016 15.0 0.0 0.075 12.8 0.0 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EME83477.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Nucleoplasmin PF03066.10 EME83478.1 - 0.054 13.0 0.8 0.084 12.3 0.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin HsdM_N PF12161.3 EME83478.1 - 0.059 13.7 0.1 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain DUF4589 PF15252.1 EME83478.1 - 0.078 12.7 2.1 0.15 11.8 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Myb_DNA-binding PF00249.26 EME83479.1 - 6e-13 48.6 1.7 3.8e-07 30.0 0.6 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME83479.1 - 1.6e-11 44.1 1.0 2e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EME83479.1 - 0.087 12.6 0.3 0.29 10.9 0.0 1.9 2 1 1 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_6 PF13921.1 EME83480.1 - 6e-13 48.6 0.1 1.1e-07 31.7 0.0 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME83480.1 - 4.6e-10 39.4 0.1 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 EME83480.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 Pkinase_Tyr PF07714.12 EME83481.1 - 0.06 12.3 0.1 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase GFA PF04828.9 EME83484.1 - 3.5e-08 33.2 0.1 3.5e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme UDPGP PF01704.13 EME83487.1 - 1.1e-181 603.9 0.0 1.3e-181 603.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ribosomal_L14 PF00238.14 EME83489.1 - 2.7e-33 114.3 0.0 3.1e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ENTH PF01417.15 EME83491.1 - 1e-48 164.3 0.5 1.4e-48 163.8 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EME83491.1 - 0.00041 19.1 0.0 0.00057 18.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EME83491.1 - 0.061 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 VHS domain Pro_isomerase PF00160.16 EME83492.1 - 1.2e-38 132.7 0.4 1.5e-38 132.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bac_rhamnosid PF05592.6 EME83493.1 - 2.3e-126 422.0 0.0 2.8e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EME83493.1 - 1.9e-49 167.4 0.0 3.1e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 EME83493.1 - 0.002 16.9 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Sugar_tr PF00083.19 EME83494.1 - 1.3e-105 353.5 20.5 1.6e-105 353.3 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83494.1 - 3.2e-30 105.0 30.0 7.8e-29 100.4 10.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EME83494.1 - 1.1e-07 30.9 1.2 1.1e-07 30.9 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Phage_holin_2 PF04550.7 EME83494.1 - 0.009 16.0 2.0 0.009 16.0 1.4 2.6 3 0 0 3 3 3 1 Phage holin family 2 FRG1 PF06229.7 EME83496.1 - 3.8e-47 160.2 9.6 4.3e-46 156.7 6.6 2.1 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EME83496.1 - 1.4e-06 28.3 0.1 0.0034 17.4 0.0 2.4 1 1 0 2 2 2 2 Fascin domain FGF PF00167.13 EME83496.1 - 0.083 12.6 0.0 6.4 6.5 0.0 2.1 1 1 0 1 1 1 0 Fibroblast growth factor DUF2244 PF10003.4 EME83496.1 - 0.16 11.3 1.3 0.24 10.7 0.9 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Cys_Met_Meta_PP PF01053.15 EME83497.1 - 8.1e-62 208.7 0.0 4.7e-61 206.2 0.0 2.1 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EME83497.1 - 0.00039 19.2 0.0 0.00064 18.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ArabFuran-catal PF09206.6 EME83499.1 - 1e-149 497.9 16.6 1.7e-149 497.1 11.5 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EME83499.1 - 7.3e-45 152.1 0.0 1.1e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) ADH_N PF08240.7 EME83502.1 - 7.3e-09 35.3 0.1 2.1e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3405 PF11885.3 EME83503.1 - 3.2e-177 589.7 15.4 1.9e-175 583.8 10.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) Herpes_Helicase PF02689.9 EME83505.1 - 0.00017 19.5 0.0 0.00017 19.4 0.0 1.0 1 0 0 1 1 1 1 Helicase OAR PF03826.12 EME83506.1 - 0.086 12.3 0.0 0.086 12.3 0.0 2.7 3 0 0 3 3 3 0 OAR domain FYVE PF01363.16 EME83507.1 - 2.1e-13 49.9 5.2 3.8e-13 49.1 0.1 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EME83507.1 - 2e-09 37.1 18.3 1e-08 34.8 2.8 3.3 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EME83507.1 - 1.8e-05 24.3 1.2 1.8e-05 24.3 0.9 3.3 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EME83507.1 - 0.001 18.4 4.1 0.4 10.1 0.6 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-rbx1 PF12678.2 EME83507.1 - 0.0091 16.0 3.5 0.0091 16.0 2.5 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME83507.1 - 0.019 15.0 3.1 0.019 15.0 2.2 3.6 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EME83507.1 - 0.046 13.5 5.5 1.7 8.4 0.1 2.7 3 0 0 3 3 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EME83507.1 - 0.1 12.3 18.1 0.13 11.9 1.9 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 HypA PF01155.14 EME83507.1 - 0.19 11.4 3.7 0.38 10.4 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FdhE PF04216.7 EME83507.1 - 0.31 10.7 1.7 16 5.0 0.1 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation RINGv PF12906.2 EME83507.1 - 0.33 11.0 10.3 0.36 10.8 4.3 2.9 3 0 0 3 3 3 0 RING-variant domain DNA_ligase_ZBD PF03119.11 EME83507.1 - 1.2 8.8 6.2 11 5.8 0.5 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.1 EME83507.1 - 2.4 7.4 6.8 3.7 6.8 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EME83507.1 - 6.9 6.2 8.7 3.6 7.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain adh_short PF00106.20 EME83508.1 - 0.003 17.5 0.1 0.0031 17.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME83508.1 - 0.0067 16.1 0.1 0.0076 15.9 0.1 1.0 1 0 0 1 1 1 1 KR domain Transaldolase PF00923.14 EME83510.1 - 2.5e-06 26.8 0.1 2.7e-06 26.7 0.1 1.0 1 0 0 1 1 1 1 Transaldolase HTH_AraC PF00165.18 EME83510.1 - 0.032 14.0 0.3 0.11 12.3 0.1 1.8 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF3405 PF11885.3 EME83511.1 - 4.6e-17 61.4 3.3 4.4e-08 31.8 0.0 3.0 1 1 1 3 3 3 3 Protein of unknown function (DUF3405) DUF2416 PF10315.4 EME83511.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) Fungal_trans PF04082.13 EME83513.1 - 6.3e-15 54.7 0.2 1.5e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med15 PF09606.5 EME83513.1 - 0.48 8.5 57.2 0.0022 16.2 33.4 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EME83513.1 - 4.2 5.4 44.7 7.1 4.7 31.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1793 PF08760.6 EME83514.1 - 1.2e-55 188.0 0.1 2.5e-55 186.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EME83514.1 - 0.00091 18.4 0.7 0.0017 17.5 0.5 1.4 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal RibD_C PF01872.12 EME83516.1 - 2.9e-38 131.4 0.0 3.5e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Pkinase PF00069.20 EME83517.1 - 4.2e-72 242.4 0.0 6e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83517.1 - 2.3e-36 125.2 0.0 4.9e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME83517.1 - 0.0014 17.6 0.1 0.46 9.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.27 EME83518.1 - 1.1e-10 40.9 3.9 7.4e-08 31.9 0.7 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Sdh5 PF03937.11 EME83519.1 - 1.4e-14 53.4 0.7 3.9e-14 52.0 0.3 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Ank_2 PF12796.2 EME83520.1 - 3.8e-10 39.9 0.0 3.9e-08 33.5 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME83520.1 - 2e-08 33.6 2.7 0.02 14.6 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat zf-C2H2 PF00096.21 EME83520.1 - 3.9e-06 26.8 31.4 0.014 15.6 3.1 6.0 6 0 0 6 6 4 4 Zinc finger, C2H2 type Ank_3 PF13606.1 EME83520.1 - 0.00027 20.8 0.0 2.3 8.7 0.0 3.8 4 0 0 4 4 3 1 Ankyrin repeat Ank_5 PF13857.1 EME83520.1 - 0.00061 19.9 0.1 0.2 11.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME83520.1 - 0.0026 18.2 0.0 0.057 13.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.1 EME83520.1 - 0.037 14.3 31.0 0.081 13.2 0.1 6.2 6 0 0 6 6 6 0 C2H2-type zinc finger HS1_rep PF02218.10 EME83520.1 - 0.087 12.7 0.3 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 Repeat in HS1/Cortactin zf-C2H2_2 PF12756.2 EME83520.1 - 0.091 12.8 18.1 0.055 13.5 3.5 4.1 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EME83520.1 - 0.23 11.6 17.7 2.2 8.5 1.3 5.0 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EME83520.1 - 0.42 10.9 17.1 21 5.6 0.3 5.5 4 0 0 4 4 4 0 Zinc-finger double domain HypA PF01155.14 EME83520.1 - 0.61 9.7 4.1 3.6 7.3 0.3 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cwf_Cwc_15 PF04889.7 EME83520.1 - 0.83 9.3 4.0 0.2 11.3 0.3 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Oxysterol_BP PF01237.13 EME83521.1 - 3.7e-90 301.9 0.0 4.8e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Ssu72 PF04722.8 EME83522.1 - 1.1e-79 266.2 0.0 1.4e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein adh_short PF00106.20 EME83523.1 - 1.3e-28 100.0 0.1 1.6e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME83523.1 - 7.3e-28 97.9 0.1 8.3e-28 97.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME83523.1 - 6.3e-16 58.5 0.1 8.9e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.17 EME83524.1 - 8.5e-31 106.9 0.0 1.5e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF1871 PF08958.5 EME83524.1 - 0.13 12.3 0.2 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) TraC PF07820.7 EME83525.1 - 0.056 13.6 0.3 0.077 13.1 0.2 1.2 1 0 0 1 1 1 0 TraC-like protein p450 PF00067.17 EME83526.1 - 5.8e-20 71.2 0.0 7.9e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EME83527.1 - 8.5e-16 57.5 0.0 1.8e-14 53.1 0.0 2.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EME83528.1 - 3.6e-38 131.2 0.0 4.3e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 EME83529.1 - 3.1e-50 170.0 0.0 6.4e-32 110.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EME83529.1 - 4.2e-33 114.9 26.8 2.2e-19 69.9 9.9 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EME83529.1 - 3.2e-07 29.8 1.5 0.36 10.0 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME83529.1 - 2.8e-05 24.2 0.1 0.51 10.2 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_25 PF13481.1 EME83529.1 - 6.9e-05 22.3 0.1 0.27 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EME83529.1 - 7.7e-05 23.1 0.1 0.029 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME83529.1 - 9.3e-05 21.4 0.1 0.25 10.2 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EME83529.1 - 0.00022 20.6 0.7 0.41 10.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EME83529.1 - 0.00048 20.2 0.4 0.84 9.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME83529.1 - 0.00063 18.9 0.3 0.86 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF2075 PF09848.4 EME83529.1 - 0.001 18.1 0.5 0.068 12.1 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.18 EME83529.1 - 0.0018 18.2 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 EME83529.1 - 0.0034 17.2 2.6 0.12 12.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EME83529.1 - 0.0048 16.3 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NB-ARC PF00931.17 EME83529.1 - 0.021 13.6 0.1 0.25 10.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EME83529.1 - 0.024 14.8 0.1 11 6.2 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EME83529.1 - 0.034 13.7 1.0 10 5.6 0.1 2.9 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 EME83529.1 - 0.047 13.6 0.1 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EME83529.1 - 0.054 13.2 0.7 2.5 7.9 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain Miro PF08477.8 EME83529.1 - 0.087 13.3 0.3 24 5.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 EME83529.1 - 0.096 13.5 0.0 4.1 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EME83529.1 - 0.12 11.8 0.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EME83529.1 - 0.16 12.2 0.1 26 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EME83529.1 - 0.21 10.6 0.1 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 EME83529.1 - 0.24 10.6 0.2 12 5.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 EME83529.1 - 0.29 10.8 3.0 31 4.2 0.0 3.7 4 0 0 4 4 4 0 NTPase AAA_16 PF13191.1 EME83529.1 - 0.32 10.9 7.4 2.2 8.2 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain AAA_10 PF12846.2 EME83529.1 - 0.76 9.1 4.7 2.3 7.6 0.3 2.8 2 1 0 2 2 2 0 AAA-like domain RasGAP_C PF03836.10 EME83532.1 - 6.5e-44 149.0 1.8 3.5e-43 146.6 0.6 2.6 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EME83532.1 - 6.5e-24 84.6 0.0 3.5e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EME83532.1 - 4.1e-08 33.2 0.0 2.2e-07 30.8 0.0 2.3 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 EME83532.1 - 0.18 11.5 54.1 2.1 8.2 0.1 12.9 13 0 0 13 13 13 0 IQ calmodulin-binding motif IMPDH PF00478.20 EME83533.1 - 3.4e-130 434.0 3.2 4.2e-130 433.7 2.2 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EME83533.1 - 1.9e-18 65.9 0.0 4.3e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EME83533.1 - 9.5e-09 34.5 0.9 2.2e-08 33.3 0.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EME83533.1 - 2.1e-05 23.8 5.0 0.0018 17.4 3.4 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 EME83533.1 - 0.00014 21.1 2.0 0.023 13.9 0.2 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein Aldolase PF01081.14 EME83533.1 - 0.036 13.2 1.9 0.084 12.0 0.1 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.9 EME83533.1 - 0.065 12.2 2.0 0.085 11.9 0.7 1.7 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 EME83533.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Glu_synthase PF01645.12 EME83533.1 - 0.19 10.5 4.8 0.35 9.7 3.3 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase AIM24 PF01987.12 EME83534.1 - 2.2e-52 177.6 0.1 2.7e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peroxidase_2 PF01328.12 EME83535.1 - 0.099 11.2 4.1 0.18 10.4 2.8 1.3 1 0 0 1 1 1 0 Peroxidase, family 2 MFS_1 PF07690.11 EME83536.1 - 4.2e-26 91.4 32.5 4.2e-26 91.4 22.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME83536.1 - 3.5e-07 28.8 3.5 6.1e-07 28.0 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PDGLE PF13190.1 EME83536.1 - 0.099 12.3 0.3 0.52 10.0 0.0 2.4 2 0 0 2 2 2 0 PDGLE domain FYVE PF01363.16 EME83541.1 - 0.0003 20.6 5.7 0.0003 20.6 3.9 3.1 3 1 0 3 3 3 1 FYVE zinc finger Fungal_trans PF04082.13 EME83543.1 - 4e-13 48.8 0.7 1.2e-07 30.9 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain fn3 PF00041.16 EME83545.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain Aldedh PF00171.17 EME83547.1 - 9.4e-142 472.5 0.0 1.2e-141 472.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EME83547.1 - 0.0082 14.9 0.0 0.035 12.8 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF3813 PF12758.2 EME83547.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) RNB PF00773.14 EME83548.1 - 2.6e-61 207.7 0.0 3.8e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 RNB domain Tim17 PF02466.14 EME83549.1 - 0.0033 17.4 3.6 0.78 9.7 0.5 2.4 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMV_coat PF00721.16 EME83549.1 - 0.035 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) HET PF06985.6 EME83550.1 - 1.4e-07 31.7 3.0 6.2e-05 23.1 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Uso1_p115_head PF04869.9 EME83551.1 - 1.2e-54 185.2 0.0 4.7e-54 183.2 0.0 2.1 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EME83551.1 - 4.3e-07 29.9 39.1 4.3e-07 29.9 27.1 5.3 1 1 5 6 6 6 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.15 EME83551.1 - 1.9e-05 23.8 53.4 1.9e-05 23.8 37.0 3.2 1 1 2 3 3 3 1 Tropomyosin Arm PF00514.18 EME83551.1 - 0.00058 19.5 1.9 0.096 12.5 0.0 3.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HCV_NS4b PF01001.14 EME83551.1 - 0.6 9.4 3.8 0.41 10.0 0.0 2.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b Tropomyosin_1 PF12718.2 EME83551.1 - 6.7 6.5 127.9 0.066 13.0 20.2 5.3 1 1 4 5 5 5 0 Tropomyosin like XRN_N PF03159.13 EME83552.1 - 2.4e-109 364.2 0.5 1.3e-108 361.8 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EME83552.1 - 0.00021 21.0 4.5 0.00039 20.2 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Arc_PepC_II PF06847.6 EME83552.1 - 0.061 13.7 0.8 22 5.5 0.0 3.3 4 0 0 4 4 4 0 Archaeal Peptidase A24 C-terminus Type II SH3_9 PF14604.1 EME83555.1 - 1.8e-12 46.6 0.0 3.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME83555.1 - 1.2e-10 40.5 0.0 2.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EME83555.1 - 6.4e-07 28.7 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_17 PF12692.2 EME83556.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase MDMPI_C PF07398.6 EME83556.1 - 0.36 11.4 1.7 0.52 10.9 1.2 1.3 1 1 0 1 1 1 0 MDMPI C-terminal domain Bac_luciferase PF00296.15 EME83560.1 - 7.4e-45 153.3 1.8 4e-42 144.3 1.3 2.1 1 1 0 1 1 1 1 Luciferase-like monooxygenase DDE_3 PF13358.1 EME83561.1 - 3.9e-05 23.4 0.0 5e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-C2H2 PF00096.21 EME83563.1 - 2.1e-05 24.5 13.5 0.0016 18.6 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME83563.1 - 0.00031 20.8 18.0 0.0093 16.2 3.6 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME83563.1 - 0.014 15.7 3.9 0.014 15.7 2.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME83563.1 - 0.026 14.6 3.8 1.2 9.4 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.20 EME83565.1 - 5.5e-13 48.6 0.0 2.2e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83565.1 - 3.5e-06 26.2 0.0 0.00089 18.3 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase RRM_1 PF00076.17 EME83569.1 - 1e-15 57.1 0.0 1.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83569.1 - 1.2e-11 44.4 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME83569.1 - 4.5e-08 32.8 0.0 6.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME83569.1 - 0.0089 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif zf-C2H2 PF00096.21 EME83570.1 - 4.6e-08 32.9 4.7 0.15 12.4 0.2 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME83570.1 - 1.1e-07 31.6 4.2 0.074 13.4 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME83570.1 - 0.00015 21.8 9.9 1.3 9.3 0.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EME83570.1 - 0.00051 20.0 0.3 0.78 9.9 0.0 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME83570.1 - 0.029 14.5 0.0 4.5 7.6 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Lipase_chap PF03280.9 EME83571.1 - 0.0074 15.8 1.8 0.011 15.3 1.3 1.2 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein CENP-F_N PF10481.4 EME83571.1 - 0.014 14.7 0.2 0.019 14.3 0.1 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain NEP PF10167.4 EME83571.1 - 0.022 14.4 0.2 0.05 13.3 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein NPV_P10 PF05531.7 EME83571.1 - 0.023 14.9 0.5 0.033 14.4 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Rossmann-like PF10727.4 EME83571.1 - 0.026 14.2 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain Prominin PF05478.6 EME83571.1 - 0.027 12.0 0.3 0.035 11.6 0.2 1.0 1 0 0 1 1 1 0 Prominin YjcZ PF13990.1 EME83571.1 - 0.03 13.4 0.5 0.044 12.9 0.3 1.2 1 0 0 1 1 1 0 YjcZ-like protein AAA_13 PF13166.1 EME83571.1 - 0.039 12.4 0.2 0.045 12.2 0.2 1.0 1 0 0 1 1 1 0 AAA domain Glutaredoxin2_C PF04399.8 EME83571.1 - 0.049 13.2 0.2 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF1664 PF07889.7 EME83571.1 - 0.063 13.0 0.5 0.095 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phlebovirus_NSM PF07246.6 EME83571.1 - 0.078 12.1 0.5 0.11 11.5 0.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Spc24 PF08286.6 EME83571.1 - 0.93 9.2 4.6 0.72 9.5 2.0 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.7 EME83571.1 - 4.3 7.7 6.4 7.5 7.0 4.4 1.4 1 0 0 1 1 1 0 SlyX Bax1-I PF01027.15 EME83575.1 - 1e-29 103.6 10.3 1.6e-29 102.9 7.2 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2237 PF09996.4 EME83576.1 - 1.2e-30 105.3 0.2 5.1e-30 103.3 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) CLTH PF10607.4 EME83577.1 - 2.5e-29 101.8 0.0 4.8e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EME83577.1 - 2.5e-24 85.7 0.1 4.7e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EME83577.1 - 1.4e-05 24.6 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 LisH INO80_Ies4 PF08193.6 EME83578.1 - 3e-42 145.0 18.3 4.3e-42 144.5 12.7 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Sel1 PF08238.7 EME83579.1 - 1.8e-42 142.8 24.7 3.7e-07 30.5 0.4 13.8 13 0 0 13 13 13 11 Sel1 repeat TPR_8 PF13181.1 EME83579.1 - 0.0021 17.6 1.8 0.78 9.6 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ADH_N PF08240.7 EME83580.1 - 1.4e-25 89.1 1.8 2.1e-25 88.5 1.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83580.1 - 1.1e-15 57.3 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EME83580.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EME83580.1 - 0.0082 16.2 0.0 0.026 14.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EME83580.1 - 0.0093 15.7 0.0 0.081 12.7 0.0 2.1 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 EME83580.1 - 0.08 11.9 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_9 PF13454.1 EME83580.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding DnaJ PF00226.26 EME83581.1 - 1.7e-13 50.0 0.1 2.7e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain SHS2_Rpb7-N PF03876.12 EME83582.1 - 1.5e-06 28.2 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Glyco_hydro_16 PF00722.16 EME83583.1 - 6.9e-32 110.2 3.7 1.1e-31 109.6 2.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 IL6Ra-bind PF09240.5 EME83583.1 - 0.007 16.5 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Interleukin-6 receptor alpha chain, binding LysM PF01476.15 EME83584.1 - 1.3e-06 28.2 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF3423 PF11903.3 EME83585.1 - 0.042 13.6 0.1 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3423) Fez1 PF06818.10 EME83585.1 - 0.098 12.6 4.8 2.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Fez1 FKS1_dom1 PF14288.1 EME83585.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 AAA_16 PF13191.1 EME83586.1 - 0.011 15.6 0.3 0.1 12.5 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EME83586.1 - 0.017 14.2 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF463 PF04317.7 EME83586.1 - 0.054 12.0 0.0 0.098 11.2 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 MMR_HSR1 PF01926.18 EME83586.1 - 0.057 13.3 0.0 0.24 11.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EME83586.1 - 0.078 13.2 0.1 0.14 12.4 0.0 1.8 2 1 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EME83586.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EME83586.1 - 0.097 12.2 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EME83586.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Isochorismatase PF00857.15 EME83587.1 - 4.4e-25 88.6 0.0 7.3e-25 87.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family FimP PF09766.4 EME83588.1 - 5.4 5.9 16.8 7.9 5.4 11.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Sugar_tr PF00083.19 EME83589.1 - 3.5e-95 319.2 32.7 4e-95 319.0 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83589.1 - 1.9e-23 82.7 34.9 4.1e-20 71.7 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kringle PF00051.13 EME83589.1 - 0.03 14.4 0.2 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Kringle domain Na_K-ATPase PF00287.13 EME83589.1 - 0.14 10.8 0.9 0.38 9.4 0.6 1.7 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain MFS_1 PF07690.11 EME83590.1 - 1.8e-34 118.9 41.3 1.8e-34 118.9 28.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1298 PF06974.8 EME83592.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Fungal_trans_2 PF11951.3 EME83594.1 - 8.3e-07 27.9 0.1 2.8e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 EME83597.1 - 3e-06 26.9 0.1 7.5e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME83597.1 - 3.9e-05 23.2 0.1 8.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Kinesin PF00225.18 EME83598.1 - 7.7e-113 376.5 0.0 1e-112 376.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SBP PF03110.9 EME83600.1 - 0.066 13.4 0.1 0.99 9.6 0.0 2.2 2 0 0 2 2 2 0 SBP domain COX5B PF01215.14 EME83601.1 - 7.1e-40 135.8 0.0 1e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb A2L_zn_ribbon PF08792.5 EME83601.1 - 0.0036 16.7 0.1 0.0068 15.8 0.0 1.5 1 1 0 1 1 1 1 A2L zinc ribbon domain CTNNB1_binding PF08347.6 EME83601.1 - 0.044 14.0 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Zn-ribbon_8 PF09723.5 EME83601.1 - 0.056 13.4 0.3 0.15 11.9 0.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain UPF0547 PF10571.4 EME83601.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 ADK_lid PF05191.9 EME83601.1 - 0.12 12.0 0.4 0.33 10.6 0.3 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid DUF2413 PF10310.4 EME83602.1 - 5.4e-129 430.8 1.6 6.2e-129 430.6 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Lipase_3 PF01764.20 EME83603.1 - 0.00044 19.8 0.0 0.0012 18.4 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EME83603.1 - 0.0055 16.1 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EME83603.1 - 0.0069 16.1 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME83603.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LRR_4 PF12799.2 EME83605.1 - 1.3e-09 37.4 2.1 0.00085 18.8 0.0 3.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME83605.1 - 2.8e-07 30.2 5.9 0.00019 21.1 0.3 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EME83605.1 - 0.003 17.3 2.8 23 5.5 0.1 4.6 3 1 1 4 4 4 1 Leucine Rich Repeat BBP1_N PF15271.1 EME83605.1 - 0.2 12.0 2.4 0.37 11.1 1.6 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Thioredoxin PF00085.15 EME83606.1 - 1.2e-09 37.8 0.2 2.2e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EME83606.1 - 0.018 15.0 0.2 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like Phage_P2_GpE PF06528.7 EME83607.1 - 0.7 9.3 7.7 22 4.6 0.2 3.7 3 1 0 3 3 3 0 Phage P2 GpE Fungal_trans PF04082.13 EME83608.1 - 1e-10 40.9 0.0 1.3e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_63 PF03200.11 EME83608.1 - 0.11 10.3 0.0 0.13 10.0 0.0 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Amino_oxidase PF01593.19 EME83609.1 - 5.7e-56 190.4 0.1 6.7e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME83609.1 - 1e-15 57.5 0.4 2.4e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME83609.1 - 3.2e-10 39.4 3.4 7.1e-08 31.7 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME83609.1 - 1.7e-05 23.8 0.4 2.8e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME83609.1 - 3.4e-05 23.0 0.1 6.3e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EME83609.1 - 6e-05 22.3 0.2 8.3e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME83609.1 - 0.0002 20.5 0.7 0.0003 19.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EME83609.1 - 0.00023 21.2 0.1 0.001 19.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME83609.1 - 0.00026 21.3 0.2 0.00053 20.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME83609.1 - 0.00038 19.0 0.2 0.00059 18.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EME83609.1 - 0.001 18.0 0.2 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EME83609.1 - 0.0019 17.2 1.2 0.0052 15.7 0.1 2.1 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME83609.1 - 0.016 15.1 0.3 0.028 14.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EME83610.1 - 3.8e-08 32.5 0.1 7.8e-08 31.4 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldose_epim PF01263.15 EME83611.1 - 7.6e-51 172.9 0.3 9.1e-51 172.7 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PARP PF00644.15 EME83612.1 - 3.2e-10 39.8 1.0 4.7e-10 39.2 0.1 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EME83612.1 - 3e-07 29.9 0.0 6.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME83612.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EME83612.1 - 0.064 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 RWD domain COG5 PF10392.4 EME83613.1 - 1.9e-05 24.6 0.6 4.2e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG7 PF10191.4 EME83613.1 - 0.0014 16.6 0.0 0.0027 15.7 0.0 1.4 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DASH_Dad2 PF08654.5 EME83613.1 - 0.0048 16.8 1.8 0.025 14.5 0.3 2.8 2 1 1 3 3 3 1 DASH complex subunit Dad2 Baculo_PEP_C PF04513.7 EME83613.1 - 0.049 13.4 2.5 0.064 13.0 0.4 2.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EME83613.1 - 0.088 12.3 3.8 0.068 12.6 0.5 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Perilipin PF03036.11 EME83613.1 - 0.14 10.9 3.6 0.19 10.5 1.5 1.7 1 1 0 2 2 2 0 Perilipin family Amidase PF01425.16 EME83614.1 - 3.1e-76 257.0 0.0 3.8e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Amidase RNA_pol_Rpc34 PF05158.7 EME83615.1 - 3.2e-64 217.1 0.0 4e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.2 EME83615.1 - 0.0024 17.4 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.2 EME83615.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.1 EME83615.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HxlR PF01638.12 EME83615.1 - 0.019 14.6 0.1 0.048 13.2 0.1 1.6 2 0 0 2 2 2 0 HxlR-like helix-turn-helix TrmB PF01978.14 EME83615.1 - 0.028 14.1 0.4 0.089 12.5 0.3 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 EME83615.1 - 0.046 13.1 0.0 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 EME83615.1 - 0.056 13.1 0.1 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 EME83615.1 - 0.13 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator zf-CCCH PF00642.19 EME83616.1 - 8.1e-09 34.9 16.5 2.8e-07 30.0 1.5 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EME83616.1 - 1.5e-06 27.9 0.1 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME83616.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83616.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NACHT PF05729.7 EME83617.1 - 5.2e-10 39.2 0.1 1.6e-09 37.6 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME83617.1 - 5.2e-05 23.3 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME83617.1 - 0.0036 17.4 0.0 0.0098 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME83617.1 - 0.049 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME83617.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SGL PF08450.7 EME83618.1 - 8.7e-62 208.6 0.1 1e-61 208.4 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NAD_binding_2 PF03446.10 EME83619.1 - 3.1e-34 118.1 0.0 6.4e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME83619.1 - 2.1e-29 102.0 0.1 2.4e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EME83619.1 - 1.8e-06 27.2 0.1 1.2e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME83619.1 - 0.00013 22.3 0.1 0.00029 21.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EME83619.1 - 0.00017 21.2 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EME83619.1 - 0.021 14.7 0.3 0.085 12.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.11 EME83619.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADSL_C PF10397.4 EME83619.1 - 0.075 13.0 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus UDPG_MGDP_dh_N PF03721.9 EME83619.1 - 0.15 11.4 0.7 2.1 7.6 0.1 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 EME83620.1 - 1.3e-23 83.4 0.0 2.4e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83620.1 - 1.1e-06 27.9 0.0 8.8e-06 24.9 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1993 PF09351.5 EME83621.1 - 0.0089 15.9 0.5 0.017 15.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) zf-C2H2 PF00096.21 EME83621.1 - 3.1 8.3 7.2 18 5.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF677 PF05055.7 EME83622.1 - 7.2 5.1 5.7 12 4.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Abhydrolase_6 PF12697.2 EME83623.1 - 5.4e-25 88.6 0.0 8.5e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME83623.1 - 8.5e-14 51.5 0.0 2e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME83623.1 - 4.7e-09 36.1 0.0 3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EME83623.1 - 1.7e-05 24.4 0.0 8.5e-05 22.2 0.0 2.1 2 1 0 2 2 2 1 PGAP1-like protein DSPc PF00782.15 EME83623.1 - 2.5e-05 23.8 0.0 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 EME83623.1 - 0.0019 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 EME83623.1 - 0.0039 16.7 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase DUF2305 PF10230.4 EME83623.1 - 0.0052 16.2 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EME83623.1 - 0.0075 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EME83623.1 - 0.011 15.2 0.1 0.048 13.2 0.0 1.9 1 1 1 2 2 2 0 Lipase (class 3) DUF1057 PF06342.7 EME83623.1 - 0.041 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 EME83623.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 1 0 Putative lysophospholipase PAF-AH_p_II PF03403.8 EME83623.1 - 0.11 10.7 0.0 3.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.9 EME83623.1 - 0.15 11.3 0.0 0.41 9.8 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Ribosomal_S19e PF01090.14 EME83624.1 - 6.7e-57 190.8 0.2 7.7e-57 190.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Defensin_beta_2 PF13841.1 EME83627.1 - 0.92 9.9 4.1 1.8 8.9 2.8 1.5 1 0 0 1 1 1 0 Beta defensin MRC1 PF09444.5 EME83631.1 - 5.4e-22 78.6 19.1 5.4e-22 78.6 13.2 7.0 6 2 1 8 8 8 1 MRC1-like domain Collagen PF01391.13 EME83632.1 - 0.00027 20.3 9.2 0.00043 19.7 6.4 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Mucin PF01456.12 EME83634.1 - 0.0099 15.6 0.4 0.011 15.4 0.3 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein XPG_I PF00867.13 EME83635.1 - 8.5e-26 89.8 0.0 2e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EME83635.1 - 2.5e-08 34.0 0.0 5.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EME83635.1 - 0.0032 17.0 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing GLTT PF01744.15 EME83636.1 - 0.26 10.7 5.7 0.093 12.1 1.6 2.1 2 0 0 2 2 2 0 GLTT repeat (6 copies) PAT1 PF09770.4 EME83637.1 - 0.019 13.2 49.9 0.025 12.8 34.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.12 EME83637.1 - 1.2 7.8 0.0 1.2 7.8 0.0 2.0 2 0 0 2 2 2 0 CLN3 protein AAA PF00004.24 EME83639.1 - 1.1e-17 64.5 0.0 2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME83639.1 - 6.8e-05 23.6 0.0 0.00042 21.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME83639.1 - 9.1e-05 22.7 0.1 0.00082 19.6 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EME83639.1 - 0.00016 21.7 0.2 0.0052 16.8 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME83639.1 - 0.00019 21.6 2.1 0.01 16.0 0.0 3.1 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.9 EME83639.1 - 0.00037 20.2 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EME83639.1 - 0.0081 15.2 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME83639.1 - 0.037 13.7 0.1 0.097 12.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EME83639.1 - 0.052 12.6 1.6 0.42 9.6 0.1 2.2 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 EME83639.1 - 0.071 13.0 0.1 0.64 9.9 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_2 PF07724.9 EME83639.1 - 0.089 12.7 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EME83639.1 - 0.098 11.7 0.1 0.25 10.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EME83639.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME83639.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_luciferase PF00296.15 EME83640.1 - 1.2e-59 201.9 0.0 1.7e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fasciclin PF02469.17 EME83641.1 - 0.081 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Fasciclin domain TRP PF06011.7 EME83642.1 - 4e-82 276.1 24.1 2e-81 273.7 16.7 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EME83642.1 - 3.2e-20 72.6 0.1 4.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain SprT-like PF10263.4 EME83643.1 - 0.0011 18.6 2.3 0.032 13.8 0.2 3.2 3 0 0 3 3 3 1 SprT-like family PMSR PF01625.16 EME83644.1 - 1.9e-58 196.7 0.2 2.3e-58 196.4 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Fungal_trans PF04082.13 EME83646.1 - 1.8e-07 30.2 0.7 3.1e-07 29.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME83646.1 - 1.6e-06 27.9 8.0 1.6e-06 27.9 5.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP8_domainIV PF12134.3 EME83647.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 PRP8 domain IV core FAD_binding_7 PF03441.9 EME83648.1 - 6.4e-100 333.9 1.8 1e-99 333.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME83648.1 - 4.5e-39 133.8 0.2 7.7e-39 133.0 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase SprT-like PF10263.4 EME83650.1 - 0.0012 18.4 0.0 0.0044 16.6 0.0 1.9 2 1 0 2 2 2 1 SprT-like family Slx4 PF09494.5 EME83651.1 - 4.1e-12 45.6 0.0 7.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease F-box PF00646.28 EME83653.1 - 0.006 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box PF00646.28 EME83654.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EME83654.1 - 0.045 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 F-box-like SprT-like PF10263.4 EME83655.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.5 1 1 0 1 1 1 1 SprT-like family DUF4344 PF14247.1 EME83655.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Sugar_tr PF00083.19 EME83656.1 - 2.3e-104 349.5 25.0 2.7e-104 349.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83656.1 - 6.5e-27 94.1 29.2 6.5e-27 94.1 20.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily HsbA PF12296.3 EME83659.1 - 2.6e-11 43.4 7.2 4.1e-11 42.7 5.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A MFS_1 PF07690.11 EME83667.1 - 5e-37 127.4 28.0 5e-37 127.4 19.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3180 PF11377.3 EME83667.1 - 0.0043 16.9 5.9 2.5 7.9 0.9 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3180) 2TM PF13239.1 EME83667.1 - 0.025 14.6 12.7 0.17 11.9 0.6 4.1 4 0 0 4 4 4 0 2TM domain FeoB_C PF07664.7 EME83667.1 - 0.033 13.5 0.0 13 5.2 0.0 3.6 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus SprT-like PF10263.4 EME83668.1 - 1.4e-06 28.0 0.0 4.2e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 SprT-like family HAP2-GCS1 PF10699.4 EME83670.1 - 0.088 12.7 0.4 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 Male gamete fusion factor C8 PF08742.6 EME83670.1 - 0.16 12.2 1.8 0.19 12.0 0.4 1.8 2 0 0 2 2 2 0 C8 domain MFS_1 PF07690.11 EME83672.1 - 2.6e-43 148.1 50.0 6.6e-40 136.9 12.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2457 PF10446.4 EME83672.1 - 0.045 12.4 4.9 0.063 12.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EME83672.1 - 0.12 11.8 1.6 0.25 10.8 1.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 EME83672.1 - 1.3 8.2 3.5 1.9 7.7 2.4 1.1 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.1 EME83672.1 - 1.8 8.9 6.0 6 7.2 4.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BAF1_ABF1 PF04684.8 EME83672.1 - 2 7.1 4.6 3 6.5 3.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FMN_dh PF01070.13 EME83675.1 - 5.3e-24 84.7 0.0 5.8e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EME83675.1 - 0.15 10.9 0.0 8 5.2 0.0 2.0 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF2231 PF09990.4 EME83676.1 - 1.7e-07 31.5 1.3 2.6e-07 30.9 0.9 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) NUDIX PF00293.23 EME83677.1 - 4.3e-14 52.3 0.1 1.9e-10 40.5 0.0 3.0 2 1 0 2 2 2 2 NUDIX domain UQ_con PF00179.21 EME83678.1 - 3.5e-21 75.0 0.0 3.8e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EME83678.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 UEV domain CoA_transf_3 PF02515.12 EME83679.1 - 2e-62 209.8 0.0 2.7e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Mg296 PF09644.5 EME83680.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Mg296 protein KxDL PF10241.4 EME83682.1 - 0.018 14.9 2.3 0.072 12.9 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein DivIC PF04977.10 EME83682.1 - 0.053 13.0 0.3 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Septum formation initiator DivIVA PF05103.8 EME83682.1 - 0.16 11.9 0.8 0.71 9.9 0.3 2.2 3 0 0 3 3 3 0 DivIVA protein Abhydrolase_6 PF12697.2 EME83683.1 - 7.4e-18 65.2 0.0 1.1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME83683.1 - 2.9e-08 33.5 0.0 6.9e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME83683.1 - 4.8e-05 23.1 0.0 5.8e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Urb2 PF10441.4 EME83684.1 - 0.2 11.2 0.6 0.36 10.3 0.4 1.4 1 0 0 1 1 1 0 Urb2/Npa2 family Zip PF02535.17 EME83686.1 - 1.2e-47 162.4 3.3 1.5e-47 162.2 2.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Leader_CPA1 PF08252.6 EME83686.1 - 0.031 13.5 0.1 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide Cutinase PF01083.17 EME83687.1 - 3.6e-37 127.8 0.3 4.1e-37 127.6 0.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EME83687.1 - 0.068 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF3089 PF11288.3 EME83687.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF336 PF03928.9 EME83689.1 - 1.1e-26 93.2 0.1 1.2e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DUF3238 PF11579.3 EME83689.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3238) CGI-121 PF08617.5 EME83690.1 - 2.4e-45 154.0 0.0 2.7e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.13 EME83691.1 - 2.7e-26 91.9 0.7 5e-26 91.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME83691.1 - 6.8e-08 32.3 10.0 1.2e-07 31.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG-CoA_red PF00368.13 EME83692.1 - 2.4e-157 523.3 4.1 3.2e-157 522.9 2.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EME83692.1 - 8.7e-34 116.4 0.0 1.5e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EME83692.1 - 3.9e-15 55.6 3.3 7.5e-15 54.7 2.3 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EME83692.1 - 1.5e-09 36.4 1.5 2.6e-09 35.6 1.0 1.3 1 0 0 1 1 1 1 Patched family DUF3605 PF12239.3 EME83693.1 - 1.7e-54 183.9 0.1 2.4e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) GIT_SHD PF08518.6 EME83694.1 - 8.9e-22 76.1 7.2 1e-13 50.3 1.6 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GAS PF13851.1 EME83694.1 - 0.0013 17.9 15.3 0.0013 17.9 10.6 3.4 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 EME83694.1 - 0.0083 13.8 39.9 0.013 13.2 27.7 1.2 1 0 0 1 1 1 1 AAA domain DUF904 PF06005.7 EME83694.1 - 0.019 15.2 1.8 0.019 15.2 1.3 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF904) ADIP PF11559.3 EME83694.1 - 0.3 10.9 61.1 0.33 10.8 2.0 4.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 EME83694.1 - 1.2 9.0 63.7 0.61 9.9 13.4 3.3 1 1 2 3 3 3 0 Tropomyosin like Filament PF00038.16 EME83694.1 - 1.3 8.4 54.9 1.1 8.6 30.2 2.7 1 1 1 2 2 2 0 Intermediate filament protein Transp_cyt_pur PF02133.10 EME83695.1 - 4.8e-44 150.6 35.5 5.6e-44 150.3 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TFR_dimer PF04253.10 EME83696.1 - 1.6e-19 69.7 0.0 2.7e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EME83696.1 - 4.8e-16 59.0 0.0 9.5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME83696.1 - 1.5e-07 30.9 0.1 3.5e-07 29.8 0.1 1.7 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EME83696.1 - 0.0007 19.1 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EME83696.1 - 0.0019 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Nicastrin Paramyx_P_V_C PF03210.8 EME83696.1 - 0.032 14.0 0.2 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal p450 PF00067.17 EME83697.1 - 2.2e-35 122.1 0.0 2.8e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3067 PF11267.3 EME83698.1 - 0.05 13.6 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3067) HET PF06985.6 EME83699.1 - 2.9e-25 89.0 0.2 3.5e-25 88.8 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p12I PF12233.3 EME83700.1 - 0.0039 17.4 0.0 0.0051 17.0 0.0 1.1 1 0 0 1 1 1 1 Human adult T cell leukemia/lymphoma virus protein TENA_THI-4 PF03070.11 EME83701.1 - 5.4e-07 29.5 1.5 1.5e-06 28.1 1.1 1.6 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Transp_cyt_pur PF02133.10 EME83702.1 - 1.1e-07 30.7 9.4 1.8e-07 30.0 6.5 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4257 PF14074.1 EME83702.1 - 0.22 11.2 1.7 5 6.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4257) zf-RING_5 PF14634.1 EME83705.1 - 0.097 12.4 2.2 0.23 11.2 1.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Abhydrolase_6 PF12697.2 EME83706.1 - 2.6e-26 92.9 0.1 5.1e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME83706.1 - 2.9e-06 27.0 0.0 7.7e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME83706.1 - 4.7e-06 26.3 0.0 6.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EME83706.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EME83706.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.9 EME83706.1 - 0.037 12.5 0.0 0.07 11.6 0.0 1.4 1 0 0 1 1 1 0 Ndr family Chlorophyllase2 PF12740.2 EME83706.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EME83706.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pribosyltran PF00156.22 EME83708.1 - 1.2e-15 57.3 0.0 1.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME83708.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EME83708.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase NIF PF03031.13 EME83709.1 - 2.2e-36 124.8 0.0 3.3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_hydro_47 PF01532.15 EME83710.1 - 4.4e-132 440.9 0.0 5.4e-132 440.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 BRF1 PF07741.8 EME83711.1 - 1.4 9.1 10.1 2.5 8.3 7.0 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Hist_deacetyl PF00850.14 EME83714.1 - 2.1e-71 240.7 0.0 2.6e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 EME83715.1 - 6.4e-21 74.6 0.2 9.9e-21 73.9 0.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EME83715.1 - 3.1e-10 39.5 9.2 5.5e-10 38.7 6.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EME83715.1 - 0.012 15.6 0.3 0.027 14.6 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EME83715.1 - 0.039 13.2 4.4 0.082 12.2 3.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EME83715.1 - 0.31 11.0 3.0 0.63 10.0 2.1 1.5 1 0 0 1 1 1 0 RING-like domain Pro_dh PF01619.13 EME83718.1 - 1.5e-33 116.1 0.4 2e-33 115.7 0.3 1.2 1 0 0 1 1 1 1 Proline dehydrogenase DIM PF08194.7 EME83719.1 - 0.18 11.7 2.1 7.9 6.5 0.0 2.7 2 0 0 2 2 2 0 DIM protein HsbA PF12296.3 EME83722.1 - 2.2e-23 82.4 9.8 3.3e-23 81.8 6.8 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Prominin PF05478.6 EME83722.1 - 0.0019 15.8 2.6 0.0023 15.5 1.8 1.0 1 0 0 1 1 1 1 Prominin DUF4032 PF13224.1 EME83722.1 - 0.12 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) AD PF09793.4 EME83722.1 - 0.12 12.2 0.4 0.31 10.9 0.1 1.9 1 1 0 1 1 1 0 Anticodon-binding domain Mer2 PF09074.5 EME83722.1 - 0.29 11.0 4.9 0.09 12.6 1.5 1.6 2 0 0 2 2 2 0 Mer2 Syntaxin_2 PF14523.1 EME83722.1 - 0.37 10.8 6.4 13 5.8 4.4 2.5 1 1 0 1 1 1 0 Syntaxin-like protein Pup PF05639.6 EME83722.1 - 0.54 10.8 3.9 0.85 10.1 0.1 2.6 1 1 1 2 2 2 0 Pup-like protein Snapin_Pallidin PF14712.1 EME83722.1 - 0.87 9.9 3.3 0.56 10.5 0.8 1.8 2 0 0 2 2 2 0 Snapin/Pallidin Pex2_Pex12 PF04757.9 EME83724.1 - 5.4e-36 124.1 4.9 8.2e-36 123.5 3.4 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region RDD PF06271.7 EME83724.1 - 0.00081 19.2 2.0 0.015 15.1 0.2 2.3 1 1 1 2 2 2 2 RDD family SUKH-4 PF14435.1 EME83724.1 - 0.028 14.1 2.6 0.063 12.9 1.8 1.6 1 0 0 1 1 1 0 SUKH-4 immunity protein zf-C3HC4_4 PF15227.1 EME83724.1 - 0.053 13.4 4.9 0.12 12.2 3.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING 6PGD PF00393.14 EME83725.1 - 5.3e-45 153.8 1.0 7.8e-27 94.2 0.0 2.1 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EME83725.1 - 5.1e-31 107.7 0.0 8.2e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EME83725.1 - 2.8e-08 33.6 0.0 5.9e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME83725.1 - 4.5e-05 23.7 0.0 9.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EME83725.1 - 0.00076 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EME83725.1 - 0.00086 18.7 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 EME83725.1 - 0.0019 18.2 0.1 0.0042 17.1 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.7 EME83725.1 - 0.074 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 EME83725.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.1 EME83725.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME83725.1 - 0.14 12.7 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 EME83725.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNF2_N PF00176.18 EME83726.1 - 2.1e-55 187.6 0.5 3.2e-55 187.0 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EME83726.1 - 2.5e-20 72.1 0.9 6.8e-20 70.7 0.7 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EME83726.1 - 3.5e-15 55.6 0.0 4.7e-13 48.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME83726.1 - 0.00011 22.0 0.0 0.00071 19.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SEC-C PF02810.10 EME83726.1 - 0.0021 17.5 5.8 0.0037 16.7 4.0 1.5 1 0 0 1 1 1 1 SEC-C motif Herpes_UL42 PF02282.11 EME83726.1 - 0.098 12.2 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) Cwf_Cwc_15 PF04889.7 EME83726.1 - 8.6 5.9 10.9 1.3 8.6 2.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_3 PF07859.8 EME83727.1 - 8.6e-06 25.4 4.7 0.025 14.1 2.7 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 EME83727.1 - 0.027 13.2 0.0 0.052 12.2 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.11 EME83728.1 - 6.7e-09 34.9 27.3 1e-08 34.3 17.1 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily JAB PF01398.16 EME83731.1 - 6.2e-30 103.2 0.0 1.2e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EME83731.1 - 5.6e-26 90.8 0.2 9.1e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EME83731.1 - 3.8e-08 32.8 0.0 7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EME83732.1 - 8e-78 261.8 0.2 1.9e-77 260.6 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Pro-kuma_activ PF09286.6 EME83733.1 - 2.2e-40 137.9 0.0 4.6e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME83733.1 - 8.4e-07 28.4 0.1 1.3e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family PCI PF01399.22 EME83734.1 - 3.8e-06 27.1 0.0 6.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF4630 PF15443.1 EME83734.1 - 0.05 13.4 1.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) INCENP_ARK-bind PF03941.10 EME83735.1 - 4.7e-16 58.3 0.4 1.7e-15 56.6 0.2 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ABC_tran PF00005.22 EME83736.1 - 1.8e-46 157.8 0.0 1.2e-28 100.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EME83736.1 - 4.1e-42 144.4 18.9 6.4e-23 81.5 7.8 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EME83736.1 - 1.4e-12 47.2 3.2 1.4e-05 24.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME83736.1 - 2.6e-09 37.4 0.0 0.045 13.7 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_23 PF13476.1 EME83736.1 - 7.6e-07 29.6 0.0 0.0072 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME83736.1 - 3.3e-06 27.2 0.1 0.063 13.4 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME83736.1 - 6e-06 25.7 0.1 0.0034 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME83736.1 - 1.8e-05 24.1 2.4 0.0093 15.4 0.7 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EME83736.1 - 0.0017 17.3 0.3 2.2 7.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EME83736.1 - 0.0028 17.5 0.4 0.47 10.4 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EME83736.1 - 0.0033 17.9 0.0 1.4 9.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EME83736.1 - 0.0038 16.7 0.2 0.2 11.0 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EME83736.1 - 0.004 17.0 0.4 0.0081 15.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_16 PF13191.1 EME83736.1 - 0.0059 16.6 8.5 0.63 9.9 0.2 4.0 4 1 0 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 EME83736.1 - 0.0099 15.0 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EME83736.1 - 0.012 15.5 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EME83736.1 - 0.013 14.9 0.2 0.76 9.1 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 EME83736.1 - 0.013 15.3 1.1 0.88 9.3 0.0 2.8 3 0 0 3 3 2 0 Dynamin family AAA_33 PF13671.1 EME83736.1 - 0.042 13.7 0.1 7.5 6.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EME83736.1 - 0.046 12.7 0.1 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EME83736.1 - 0.048 13.4 0.2 17 5.2 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EME83736.1 - 0.058 14.2 0.5 1.7 9.4 0.4 2.9 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EME83736.1 - 0.08 12.4 1.5 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EME83736.1 - 0.081 13.2 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME83736.1 - 0.1 12.2 0.2 5.1 6.7 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase GTP_EFTU PF00009.22 EME83736.1 - 0.1 11.9 0.2 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.4 EME83736.1 - 0.11 11.0 4.0 0.48 8.9 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MobB PF03205.9 EME83736.1 - 0.12 12.0 0.5 5.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EME83736.1 - 0.23 10.8 3.2 9.6 5.6 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EME83736.1 - 0.67 9.2 4.0 1.3 8.2 0.1 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein NACHT PF05729.7 EME83736.1 - 1.7 8.3 5.0 8.3 6.0 0.1 3.0 3 0 0 3 3 3 0 NACHT domain DEAD PF00270.24 EME83736.1 - 4.2 6.8 5.0 1.6e+02 1.7 3.0 3.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase Alpha-amylase PF00128.19 EME83737.1 - 3.7e-17 62.7 1.2 3.3e-16 59.5 0.8 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EME83737.1 - 1.7e-14 53.9 0.1 3e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EME83737.1 - 3e-07 30.0 0.0 5.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME83737.1 - 3.9e-07 30.3 0.0 9.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Rtt106 PF08512.7 EME83739.1 - 9.7e-27 92.7 0.0 1.8e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Ydc2-catalyt PF09159.5 EME83742.1 - 1.6e-54 185.2 0.0 2.8e-54 184.4 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EME83742.1 - 2.5e-06 27.4 0.0 0.055 13.3 0.0 3.2 2 1 0 2 2 2 1 Poxvirus A22 protein Peptidase_M24 PF00557.19 EME83742.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 Aa_trans PF01490.13 EME83743.1 - 2.1e-76 257.0 30.5 2.5e-76 256.8 21.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF21 PF01595.15 EME83743.1 - 1.5 8.0 9.1 0.13 11.5 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF21 Sec23_trunk PF04811.10 EME83744.1 - 2e-75 253.2 0.0 3e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EME83744.1 - 2.1e-34 117.0 0.2 5.3e-34 115.7 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EME83744.1 - 3.5e-29 101.1 0.0 8.1e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EME83744.1 - 1.4e-16 59.7 8.2 2.8e-16 58.7 5.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EME83744.1 - 5.5e-08 32.3 0.0 1.4e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Gelsolin repeat Pkinase PF00069.20 EME83746.1 - 1.1e-35 123.0 0.0 1.5e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83746.1 - 1.3e-14 53.9 0.0 1.8e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME83746.1 - 0.01 15.5 0.0 0.34 10.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC27 PF09507.5 EME83746.1 - 0.42 9.7 7.2 0.62 9.2 5.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 F-box-like PF12937.2 EME83747.1 - 0.0031 17.2 0.0 0.079 12.7 0.2 3.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME83747.1 - 0.024 14.3 0.4 2.2 8.0 0.2 3.1 2 0 0 2 2 2 0 F-box domain F-box PF00646.28 EME83749.1 - 0.0062 16.1 0.1 3.5 7.4 0.0 3.1 2 1 0 2 2 2 2 F-box domain USP7_C2 PF14533.1 EME83749.1 - 0.23 10.8 0.3 9.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal Ribosomal_S21 PF01165.15 EME83749.1 - 1.3 8.5 8.4 2.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S21 DUF1977 PF09320.6 EME83750.1 - 1.3e-23 83.3 0.0 1.9e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EME83750.1 - 6e-23 80.3 0.1 1.2e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2416 PF10315.4 EME83751.1 - 1.5e-05 25.1 0.2 2.8e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) MFS_1_like PF12832.2 EME83751.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 MFS_1 like family RALF PF05498.6 EME83752.1 - 0.0025 18.6 0.0 0.0052 17.5 0.0 1.6 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) ABC_membrane PF00664.18 EME83753.1 - 3.5e-76 256.2 33.7 2e-38 132.4 9.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME83753.1 - 6.5e-68 227.2 0.0 2.7e-33 115.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME83753.1 - 5.3e-14 52.8 0.0 0.0044 17.0 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EME83753.1 - 6.2e-12 45.2 9.4 3.6e-05 23.0 2.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EME83753.1 - 2.3e-08 34.2 1.0 0.006 16.5 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EME83753.1 - 2.4e-08 33.0 1.3 0.002 16.7 0.0 3.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 EME83753.1 - 3.3e-08 33.1 0.3 0.0005 19.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EME83753.1 - 4.2e-07 29.2 1.9 0.005 16.0 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME83753.1 - 4.7e-07 29.2 2.6 0.00073 19.0 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EME83753.1 - 1.3e-06 28.5 1.7 0.016 15.3 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EME83753.1 - 1.5e-06 28.4 1.9 0.0015 18.7 0.2 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME83753.1 - 7.3e-06 26.8 0.1 0.17 12.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EME83753.1 - 0.00011 21.8 1.5 1.7 8.1 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 EME83753.1 - 0.00012 21.8 0.1 1.4 8.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EME83753.1 - 0.0002 21.2 3.5 0.19 11.6 0.2 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EME83753.1 - 0.002 18.4 0.1 2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EME83753.1 - 0.0038 16.6 0.2 2.3 7.6 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EME83753.1 - 0.0048 16.7 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EME83753.1 - 0.0078 15.9 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EME83753.1 - 0.0093 15.5 0.1 6.1 6.3 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EME83753.1 - 0.011 16.1 1.6 3.1 8.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EME83753.1 - 0.013 14.9 3.4 2.5 7.4 0.0 3.9 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 EME83753.1 - 0.016 15.3 0.1 2.8 8.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EME83753.1 - 0.018 15.0 0.2 1 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EME83753.1 - 0.051 12.2 0.1 2.9 6.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 EME83753.1 - 0.081 11.6 0.0 0.31 9.6 0.0 1.9 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein DUF87 PF01935.12 EME83753.1 - 0.083 12.6 0.3 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EME83753.1 - 0.13 11.9 0.3 11 5.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Fungal_trans PF04082.13 EME83754.1 - 1.7e-15 56.5 0.0 3.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2_5_RNA_ligase2 PF13563.1 EME83754.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily ROKNT PF08067.6 EME83754.1 - 0.036 13.9 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 ROKNT (NUC014) domain DUF2892 PF11127.3 EME83755.1 - 0.1 12.4 1.4 0.41 10.5 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Rad52_Rad22 PF04098.10 EME83757.1 - 9.2e-60 200.8 0.0 1.3e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Peptidase_S10 PF00450.17 EME83758.1 - 4.8e-115 385.0 0.0 6.3e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PRELI PF04707.9 EME83759.1 - 1.4e-40 138.4 0.2 1.6e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 EME83759.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Yae1_N PF09811.4 EME83760.1 - 3.9e-09 35.8 5.3 7.5e-09 34.9 3.6 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal AAA_27 PF13514.1 EME83760.1 - 0.019 12.6 0.1 0.024 12.3 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF3176 PF11374.3 EME83762.1 - 1.5e-17 63.4 1.0 6.5e-17 61.4 0.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) Mid2 PF04478.7 EME83764.1 - 0.002 17.5 1.8 0.002 17.5 1.2 3.3 1 1 3 4 4 4 1 Mid2 like cell wall stress sensor TrbC PF04956.8 EME83764.1 - 0.0056 16.6 1.5 0.009 16.0 0.2 2.1 2 0 0 2 2 2 1 TrbC/VIRB2 family DUF533 PF04391.7 EME83764.1 - 0.041 13.2 0.9 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) DUF2029 PF09594.5 EME83764.1 - 0.1 12.0 0.4 0.17 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) CRM1_C PF08767.6 EME83769.1 - 8.5e-111 369.8 21.5 3.2e-74 249.7 1.1 3.9 5 0 0 5 5 5 2 CRM1 C terminal Xpo1 PF08389.7 EME83769.1 - 1.3e-38 132.1 12.3 8.6e-38 129.5 4.4 4.4 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EME83769.1 - 5.2e-12 45.5 0.5 2.3e-11 43.4 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain HD_assoc PF13286.1 EME83769.1 - 0.033 14.4 0.7 20 5.5 0.1 3.6 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Vac14_Fab1_bd PF12755.2 EME83769.1 - 0.69 10.3 5.4 6.9 7.1 0.0 4.5 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region PPI_Ypi1 PF07491.6 EME83770.1 - 1.7e-23 82.0 0.2 3.3e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor NR_Repeat PF14046.1 EME83770.1 - 0.33 10.7 2.5 0.72 9.6 1.7 1.6 1 0 0 1 1 1 0 Nuclear receptor repeat DASH_Dad2 PF08654.5 EME83771.1 - 2.5e-32 110.9 1.9 3.7e-32 110.3 1.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF1484 PF07363.6 EME83771.1 - 0.031 14.6 0.7 1.4 9.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1484) Citrate_synt PF00285.16 EME83771.1 - 0.062 12.0 0.9 0.073 11.7 0.6 1.1 1 0 0 1 1 1 0 Citrate synthase GCN5L1 PF06320.8 EME83771.1 - 0.067 13.0 0.5 0.24 11.2 0.3 1.9 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Suppressor_APC PF11414.3 EME83771.1 - 0.067 12.9 1.6 0.1 12.4 0.6 1.8 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein GvpL_GvpF PF06386.6 EME83771.1 - 0.14 11.7 1.8 0.2 11.2 1.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Seryl_tRNA_N PF02403.17 EME83771.1 - 2.1 8.3 7.5 0.46 10.5 0.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.6 EME83772.1 - 1.5e-13 50.2 7.7 3.4e-13 49.0 5.3 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EME83772.1 - 1.8e-11 43.3 4.5 1.8e-11 43.3 3.1 4.1 6 0 0 6 6 6 1 Shugoshin C terminus Septin PF00735.13 EME83774.1 - 5.1e-113 376.7 0.3 6.2e-113 376.4 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EME83774.1 - 8e-07 29.0 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EME83774.1 - 1.6e-05 24.1 0.0 3.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EME83774.1 - 4.7e-05 22.6 0.0 8.4e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EME83774.1 - 5.3e-05 22.7 0.1 0.02 14.3 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EME83774.1 - 0.00082 19.2 0.4 1.4 8.6 0.1 2.5 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 EME83774.1 - 0.0024 17.3 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EME83774.1 - 0.0032 16.9 0.1 0.0039 16.6 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 EME83774.1 - 0.0076 15.4 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EME83774.1 - 0.0082 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME83774.1 - 0.011 15.8 0.1 0.033 14.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EME83774.1 - 0.012 14.5 0.0 0.047 12.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EME83774.1 - 0.016 14.1 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EME83774.1 - 0.026 14.8 0.9 0.039 14.2 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EME83774.1 - 0.03 14.6 0.1 0.081 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EME83774.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.18 EME83775.1 - 5.8e-13 48.8 5.1 8.6e-13 48.2 3.5 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family HSP70 PF00012.15 EME83776.1 - 0.019 12.8 0.5 0.049 11.5 0.0 1.8 2 1 0 2 2 2 0 Hsp70 protein Peptidase_M22 PF00814.20 EME83776.1 - 0.093 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycoprotease family PHD PF00628.24 EME83777.1 - 8.3e-07 28.6 9.0 1.8e-06 27.5 6.2 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EME83777.1 - 0.011 15.7 0.9 0.038 13.9 0.6 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EME83777.1 - 0.78 9.7 5.8 1.5 8.8 4.0 1.5 1 0 0 1 1 1 0 RING-like domain COesterase PF00135.23 EME83778.1 - 2.1e-76 257.7 0.3 2.6e-76 257.4 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME83778.1 - 0.00028 20.5 1.6 0.0013 18.3 0.6 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME83778.1 - 0.044 13.0 0.6 0.1 11.7 0.4 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME83778.1 - 0.15 11.8 1.5 0.27 10.9 0.9 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family mRNA_cap_enzyme PF01331.14 EME83780.1 - 8e-46 156.1 0.0 1.2e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EME83780.1 - 1.5e-12 47.7 1.7 2.3e-12 47.1 0.0 2.2 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EME83780.1 - 0.00015 21.2 2.8 0.00059 19.2 0.0 2.6 2 1 0 2 2 2 1 ATP dependent DNA ligase domain UPF0542 PF15086.1 EME83780.1 - 2.9 7.6 8.4 5.8 6.6 5.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF2422 PF10337.4 EME83780.1 - 9.6 4.8 6.6 13 4.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Ubiq_cyt_C_chap PF03981.7 EME83781.1 - 1.8e-36 125.1 0.4 2.1e-36 124.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone PhyH PF05721.8 EME83782.1 - 1.1e-08 35.4 1.3 8.9e-08 32.4 0.1 2.5 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EME83782.1 - 2.1e-07 29.8 0.5 0.0065 15.0 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Kelch_2 PF07646.10 EME83782.1 - 0.31 10.8 3.3 1.1 9.1 0.7 2.3 2 0 0 2 2 2 0 Kelch motif RINGv PF12906.2 EME83784.1 - 2.8e-16 59.2 9.5 5.9e-16 58.2 6.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EME83784.1 - 0.059 13.2 9.1 0.14 11.9 6.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EME83784.1 - 0.11 12.3 2.6 0.38 10.6 1.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IncA PF04156.9 EME83784.1 - 0.29 10.6 5.2 1.1 8.8 3.6 2.0 1 0 0 1 1 1 0 IncA protein NUDIX PF00293.23 EME83788.1 - 8.6e-17 61.0 0.8 1.1e-15 57.4 0.1 2.2 2 1 0 2 2 2 2 NUDIX domain WD40 PF00400.27 EME83789.1 - 2.2e-78 255.5 18.5 8.3e-14 50.8 1.2 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EME83789.1 - 3.3e-09 35.4 2.3 0.00036 18.8 0.8 3.8 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME83789.1 - 2.5e-07 29.8 0.0 0.16 10.6 0.1 3.7 1 1 1 3 3 3 3 Nup133 N terminal like p450 PF00067.17 EME83790.1 - 3.1e-41 141.3 0.0 4.4e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_76 PF03663.9 EME83791.1 - 1.1e-125 419.9 15.1 1.3e-125 419.6 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EME83791.1 - 0.011 14.7 5.5 0.25 10.3 0.4 2.2 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 DUF3115 PF11312.3 EME83791.1 - 0.062 12.1 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Zn_clus PF00172.13 EME83795.1 - 0.0043 16.9 7.9 0.01 15.7 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.10 EME83796.1 - 2.3e-14 52.6 0.0 5.2e-14 51.5 0.0 1.6 2 0 0 2 2 2 1 Transferase family Glyco_hydro_3 PF00933.16 EME83797.1 - 5e-87 291.6 0.0 7.1e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME83797.1 - 2.3e-48 164.7 0.1 4.7e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME83797.1 - 1.4e-23 82.6 0.0 2.6e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DND1_DSRM PF14709.1 EME83798.1 - 0.0047 17.1 0.6 0.011 16.0 0.4 1.6 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EME83798.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Flavi_propep PF01570.12 EME83798.1 - 0.033 13.9 0.2 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide BRAP2 PF07576.7 EME83799.1 - 9.9e-22 76.6 0.0 1.9e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EME83799.1 - 8.3e-20 70.6 7.2 2.5e-19 69.1 5.0 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EME83799.1 - 2.2e-09 36.9 9.6 2.2e-09 36.9 6.6 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME83799.1 - 1.8e-05 24.3 7.3 5e-05 22.8 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME83799.1 - 0.00022 20.8 6.5 0.00022 20.8 4.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME83799.1 - 0.00028 20.9 4.5 0.001 19.0 3.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME83799.1 - 0.00094 19.1 8.6 0.00094 19.1 5.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME83799.1 - 0.0015 18.1 7.1 0.0015 18.1 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EME83799.1 - 0.0023 17.6 3.4 0.0079 15.9 2.4 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EME83799.1 - 0.0038 16.9 4.1 0.0053 16.4 1.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EME83799.1 - 0.023 14.5 5.6 0.063 13.1 3.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EME83799.1 - 0.025 14.3 1.1 0.13 12.1 0.2 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.1 EME83799.1 - 1.1 8.8 9.6 26 4.4 6.7 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Syntaxin-6_N PF09177.6 EME83799.1 - 1.9 8.9 10.5 0.91 9.9 5.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF445 PF04286.7 EME83799.1 - 1.9 7.9 8.6 3 7.2 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Exonuc_VII_L PF02601.10 EME83799.1 - 2.8 7.0 11.9 4.6 6.3 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.7 EME83799.1 - 2.9 7.6 11.7 1.5 8.5 5.5 2.0 1 1 1 2 2 2 0 Laminin Domain II ubiquitin PF00240.18 EME83800.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EME83800.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME83800.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME83800.1 - 8.6e-17 61.2 0.5 0.00048 19.8 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EME83800.1 - 6.7e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME83800.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EME83800.1 - 5.1e-08 32.8 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EME83800.1 - 2e-05 24.4 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 EME83800.1 - 0.00016 21.2 0.5 7.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 EME83800.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EME83800.1 - 0.00084 18.5 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Plexin_cytopl PF08337.7 EME83800.1 - 0.00084 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EME83800.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 EME83800.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 EME83800.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 EME83800.1 - 0.033 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EME83800.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 EME83800.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 EME83800.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 EME83800.1 - 0.092 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 EME83800.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 EME83800.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 EME83800.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat Methyltransf_23 PF13489.1 EME83801.1 - 3e-23 82.3 0.0 5.5e-23 81.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME83801.1 - 2.1e-11 44.1 0.0 4.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME83801.1 - 4.2e-10 39.4 0.0 2.5e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME83801.1 - 4e-09 37.0 0.1 5.6e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME83801.1 - 1.1e-08 35.4 0.0 6.9e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME83801.1 - 5.5e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME83801.1 - 0.00035 20.5 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME83801.1 - 0.003 16.9 0.0 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EME83801.1 - 0.0052 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EME83801.1 - 0.008 15.3 0.0 0.035 13.2 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EME83801.1 - 0.0083 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.10 EME83801.1 - 0.024 13.7 0.0 0.19 10.8 0.0 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G CMAS PF02353.15 EME83801.1 - 0.032 13.3 0.0 0.076 12.0 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EME83801.1 - 0.097 11.7 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EME83801.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EME83801.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase p450 PF00067.17 EME83802.1 - 3.6e-47 160.9 0.0 4.8e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Catalase PF00199.14 EME83803.1 - 2e-164 546.8 0.1 2.5e-164 546.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EME83803.1 - 5.7e-17 61.3 0.0 2.2e-16 59.4 0.0 2.1 1 0 0 1 1 1 1 Catalase-related immune-responsive RRM_1 PF00076.17 EME83806.1 - 2.2e-37 126.5 0.1 1e-11 44.2 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83806.1 - 1.1e-36 124.6 0.0 1.9e-08 34.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME83806.1 - 3.1e-17 62.1 0.0 0.0013 18.5 0.2 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EME83806.1 - 2.2e-10 39.9 6.4 2.2e-10 39.9 4.4 3.0 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EME83806.1 - 1.8e-05 24.4 0.1 0.07 12.9 0.1 2.8 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EME83806.1 - 0.06 13.3 0.0 0.57 10.2 0.0 2.7 3 0 0 3 3 3 0 RNA binding domain Nup35_RRM_2 PF14605.1 EME83806.1 - 0.11 12.2 0.0 37 4.1 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_47 PF01532.15 EME83807.1 - 3.3e-179 596.3 1.9 3.8e-179 596.0 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alg6_Alg8 PF03155.10 EME83808.1 - 3.6e-143 477.8 27.5 4.4e-143 477.5 19.0 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EME83809.1 - 6.5e-23 80.8 2.0 9.9e-23 80.2 0.1 2.4 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EME83809.1 - 6.9e-12 44.9 1.2 1.2e-11 44.2 0.8 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EME83809.1 - 5.3e-10 38.8 0.4 1.1e-09 37.7 0.3 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EME83809.1 - 0.00013 21.6 2.4 0.00057 19.6 1.7 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Choline_kinase PF01633.15 EME83809.1 - 0.0072 15.9 0.2 0.047 13.2 0.2 2.3 1 1 0 1 1 1 1 Choline/ethanolamine kinase V_ATPase_I PF01496.14 EME83809.1 - 0.85 7.3 3.0 0.41 8.4 0.5 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF812 PF05667.6 EME83809.1 - 4.6 5.6 21.8 0.31 9.5 10.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF812) Effector_1 PF04518.7 EME83809.1 - 9.6 5.0 9.6 3.1 6.6 4.1 2.0 2 0 0 2 2 2 0 Effector from type III secretion system Ferrochelatase PF00762.14 EME83810.1 - 8.6e-93 310.7 0.0 1e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 EME83811.1 - 2.5e-38 131.5 0.0 4.8e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EME83811.1 - 2.5e-30 105.5 0.0 3.8e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EME83811.1 - 8.8e-13 48.6 3.0 1.1e-12 48.3 0.4 2.5 2 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EME83811.1 - 2.4e-07 30.0 0.0 4.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EME83811.1 - 0.0013 18.9 0.5 0.0032 17.5 0.3 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Ifi-6-16 PF06140.8 EME83812.1 - 6.4e-05 22.6 13.6 8.6e-05 22.2 9.4 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF3253 PF11625.3 EME83814.1 - 2.6e-11 43.2 0.0 3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Pec_lyase_C PF00544.14 EME83815.1 - 1.9e-20 73.1 0.8 2.8e-20 72.6 0.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EME83815.1 - 0.0037 17.0 13.7 0.017 14.8 9.6 2.0 1 1 0 1 1 1 1 Right handed beta helix region Carboxyl_trans PF01039.17 EME83816.1 - 1.1e-144 482.5 0.1 1.3e-144 482.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EME83816.1 - 0.0059 15.8 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 EME83817.1 - 2.5e-37 128.3 0.5 5.2e-37 127.2 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME83817.1 - 3.6e-31 108.0 1.0 7.9e-31 106.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EME83817.1 - 8.6e-19 66.8 0.2 2e-18 65.6 0.1 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EME83817.1 - 1.8e-11 44.4 0.4 4e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EME83817.1 - 0.034 13.5 0.3 0.11 11.9 0.2 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.1 EME83817.1 - 0.038 14.2 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal IncA PF04156.9 EME83818.1 - 0.00051 19.6 14.0 0.00051 19.6 9.7 3.1 1 1 2 3 3 3 1 IncA protein DUF869 PF05911.6 EME83818.1 - 0.015 13.5 29.5 0.0078 14.5 17.5 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Peptidase_M15_3 PF08291.6 EME83818.1 - 0.02 14.6 3.8 1.7 8.4 0.0 3.3 3 0 0 3 3 3 0 Peptidase M15 SlyX PF04102.7 EME83818.1 - 0.03 14.6 2.1 0.03 14.6 1.4 4.9 2 2 3 5 5 5 0 SlyX AAA_13 PF13166.1 EME83818.1 - 0.041 12.3 22.5 0.021 13.3 9.9 2.5 1 1 1 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 EME83818.1 - 0.093 11.8 13.2 0.058 12.5 0.8 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Flagellin_C PF00700.16 EME83818.1 - 0.15 12.2 11.1 1.9 8.7 0.4 3.9 1 1 3 4 4 4 0 Bacterial flagellin C-terminal helical region WEMBL PF05701.6 EME83818.1 - 0.22 9.9 36.3 0.036 12.5 14.3 2.5 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Kinetocho_Slk19 PF12709.2 EME83818.1 - 0.55 10.3 20.5 0.68 10.0 0.2 4.7 4 1 0 4 4 4 0 Central kinetochore-associated Tweety PF04906.8 EME83818.1 - 0.59 8.4 11.3 1.8 6.9 0.5 2.8 1 1 1 3 3 3 0 Tweety DUF948 PF06103.6 EME83818.1 - 0.61 9.9 8.5 0.046 13.5 0.9 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF641 PF04859.7 EME83818.1 - 1.1 8.9 24.2 0.085 12.6 0.5 4.2 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.7 EME83818.1 - 2.2 8.0 18.4 0.59 9.9 0.5 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 EME83818.1 - 2.5 7.1 39.0 0.98 8.4 15.0 3.2 1 1 1 2 2 2 0 Tropomyosin Lebercilin PF15619.1 EME83818.1 - 3.5 7.0 42.6 0.71 9.2 13.6 3.7 1 1 4 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease TPD52 PF04201.10 EME83818.1 - 3.9 7.1 17.0 0.072 12.8 4.5 2.7 2 2 0 2 2 2 0 Tumour protein D52 family DUF972 PF06156.8 EME83818.1 - 5.5 7.3 24.8 2.7 8.3 0.6 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Striatin PF08232.7 EME83820.1 - 0.17 12.2 0.4 0.36 11.1 0.1 1.7 2 0 0 2 2 2 0 Striatin family HrpB7 PF09486.5 EME83821.1 - 0.033 14.1 0.6 0.033 14.1 0.4 2.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) FtsQ PF03799.10 EME83821.1 - 0.054 13.6 0.7 0.17 12.0 0.5 1.7 1 1 0 1 1 1 0 Cell division protein FtsQ HR1 PF02185.11 EME83821.1 - 0.077 12.7 4.8 0.13 11.9 3.3 1.4 1 0 0 1 1 1 0 Hr1 repeat DUF4140 PF13600.1 EME83821.1 - 0.13 12.7 2.5 0.28 11.6 1.7 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) THOC7 PF05615.8 EME83821.1 - 0.52 10.5 4.2 0.57 10.4 2.5 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 Autophagy_N PF03986.8 EME83822.1 - 1.4e-41 141.6 0.2 2.4e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EME83822.1 - 6.2e-23 80.7 0.4 1.3e-22 79.6 0.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EME83822.1 - 1.5e-14 52.7 0.4 2.6e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Myelin_MBP PF01669.12 EME83822.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Myelin basic protein DUF2457 PF10446.4 EME83822.1 - 0.86 8.2 7.6 1.5 7.4 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pyr_redox PF00070.22 EME83823.1 - 2.1e-18 66.5 0.2 7.1e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME83823.1 - 1.2e-16 61.1 0.0 2.4e-14 53.6 0.0 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME83823.1 - 2.2e-13 50.7 0.0 5.9e-07 29.7 0.0 3.5 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME83823.1 - 1.4e-11 43.9 0.0 0.0026 16.7 0.0 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EME83823.1 - 4.5e-08 32.4 0.1 2.2e-07 30.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EME83823.1 - 1.8e-06 28.1 0.0 0.0056 16.9 0.0 3.0 3 0 0 3 3 3 2 Putative NAD(P)-binding Trp_halogenase PF04820.9 EME83823.1 - 5.3e-06 25.3 0.0 0.31 9.6 0.0 3.2 2 1 1 3 3 3 3 Tryptophan halogenase Lycopene_cycl PF05834.7 EME83823.1 - 0.00032 19.7 0.0 0.78 8.5 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME83823.1 - 0.00035 20.3 0.1 20 4.8 0.0 4.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME83823.1 - 0.0027 17.6 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EME83823.1 - 0.0079 16.1 0.3 0.42 10.6 0.0 2.7 3 0 0 3 3 3 1 TrkA-N domain FAD_binding_3 PF01494.14 EME83823.1 - 0.02 13.9 1.0 6.2 5.7 0.0 3.1 2 1 1 3 3 3 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EME83823.1 - 0.061 12.7 0.1 7.8 5.8 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TFIID-18kDa PF02269.11 EME83824.1 - 2e-18 65.9 0.0 3.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EME83824.1 - 0.006 16.6 0.1 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EME83824.1 - 0.042 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF1242 PF06842.7 EME83825.1 - 8.7e-16 57.1 1.8 1.2e-15 56.7 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF624 PF04854.9 EME83825.1 - 0.024 14.4 0.2 0.024 14.4 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF418 PF04235.7 EME83825.1 - 0.034 13.8 0.3 0.034 13.8 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF418) Zn_clus PF00172.13 EME83826.1 - 4.3e-09 36.1 10.8 9.8e-09 34.9 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME83826.1 - 1.7e-05 23.6 0.0 2.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DENN PF02141.16 EME83828.1 - 1.8e-53 181.0 0.0 3.3e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EME83828.1 - 2.4e-17 62.7 3.0 3.4e-17 62.2 0.8 2.1 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.13 EME83828.1 - 9.7e-17 60.6 0.1 2e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 uDENN domain C1_1 PF00130.17 EME83828.1 - 0.0014 18.3 11.4 0.0026 17.4 7.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 EME83828.1 - 0.0034 17.4 9.0 0.0034 17.4 6.2 2.0 2 0 0 2 2 2 1 C1 domain PHD_2 PF13831.1 EME83828.1 - 0.026 13.8 0.8 0.059 12.6 0.5 1.6 1 0 0 1 1 1 0 PHD-finger SPA PF08616.5 EME83828.1 - 0.23 11.1 0.0 0.46 10.1 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.24 EME83828.1 - 0.44 10.2 13.1 0.25 11.0 6.8 2.2 2 0 0 2 2 2 0 PHD-finger DUF974 PF06159.8 EME83831.1 - 1.4e-53 181.9 0.0 1.7e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) SET PF00856.23 EME83832.1 - 5.9e-14 52.6 0.0 3.1e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EME83832.1 - 0.11 12.9 0.1 5.9 7.3 0.0 2.2 2 0 0 2 2 2 0 SAF domain GST_N_2 PF13409.1 EME83833.1 - 1.1e-14 54.1 0.0 3.1e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME83833.1 - 7.9e-06 25.6 0.0 3.8e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME83833.1 - 0.00016 22.0 0.0 0.003 18.0 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME83833.1 - 0.0028 17.8 0.0 0.021 15.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain 7tm_6 PF02949.15 EME83834.1 - 0.013 14.4 1.1 0.019 13.8 0.8 1.2 1 0 0 1 1 1 0 7tm Odorant receptor Sec61_beta PF03911.11 EME83836.1 - 6.6e-19 67.4 1.1 1e-18 66.8 0.8 1.3 1 0 0 1 1 1 1 Sec61beta family Aldo_ket_red PF00248.16 EME83837.1 - 1.8e-49 168.1 0.0 2e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zip PF02535.17 EME83838.1 - 5.4e-32 111.0 19.3 3e-30 105.3 13.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter SPT6_acidic PF14632.1 EME83838.1 - 6.2 7.0 10.5 0.43 10.7 1.0 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ank_5 PF13857.1 EME83839.1 - 2.6e-07 30.6 0.1 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EME83839.1 - 2.1e-05 24.1 0.1 5.8e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EME83839.1 - 0.00021 21.7 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME83839.1 - 0.00072 19.8 0.1 0.0025 18.1 0.1 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EME83839.1 - 0.019 15.1 0.0 0.069 13.4 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat DUF1162 PF06650.7 EME83841.1 - 4e-86 288.6 0.0 5.1e-85 285.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EME83841.1 - 3.7e-42 142.5 0.1 1.2e-41 140.9 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EME83841.1 - 0.0016 18.5 0.1 0.024 14.7 0.0 2.9 3 0 0 3 3 3 1 ATG C terminal domain Methyltransf_16 PF10294.4 EME83842.1 - 2.1e-15 56.5 0.0 2.9e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase DUF4366 PF14283.1 EME83845.1 - 0.11 11.8 0.1 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CDC45 PF02724.9 EME83845.1 - 0.59 8.0 9.6 0.85 7.5 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 EME83846.1 - 2e-21 76.1 18.7 2e-21 76.1 12.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Citrate_ly_lig PF08218.6 EME83846.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DUF4017 PF13209.1 EME83846.1 - 3.6 7.4 6.0 0.53 10.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4017) Peroxidase_2 PF01328.12 EME83847.1 - 2.3e-21 75.7 0.0 2.7e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Mur_ligase_M PF08245.7 EME83848.1 - 0.0077 16.2 0.1 0.087 12.8 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Ribosom_S12_S23 PF00164.20 EME83850.1 - 7.4e-41 138.3 0.4 8.8e-41 138.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ACP_syn_III PF08545.5 EME83851.1 - 3.3e-06 26.6 0.0 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EME83851.1 - 3.2e-05 23.0 0.3 8.7e-05 21.6 0.0 1.9 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME83851.1 - 0.00035 19.9 0.3 0.00035 19.9 0.2 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME83851.1 - 0.00055 19.4 0.1 0.0046 16.4 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EME83851.1 - 0.0067 14.9 0.1 0.013 13.9 0.1 1.4 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 EME83851.1 - 0.087 12.6 0.5 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain BRO1 PF03097.13 EME83852.1 - 1e-117 393.0 4.1 1.9e-117 392.2 0.1 2.5 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EME83852.1 - 9.2e-75 251.3 16.8 9.2e-75 251.3 11.6 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV HMA PF00403.21 EME83853.1 - 2.2e-17 62.9 1.0 2.7e-17 62.6 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF148 PF02520.12 EME83853.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF1677 PF07911.8 EME83853.1 - 0.079 13.1 0.1 0.095 12.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) Pec_lyase_C PF00544.14 EME83854.1 - 2.1e-42 144.8 6.3 2.9e-42 144.4 4.4 1.2 1 0 0 1 1 1 1 Pectate lyase SRR1 PF07985.7 EME83856.1 - 3.8e-05 23.5 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 Abhydrolase_6 PF12697.2 EME83857.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 EME83858.1 - 9.6e-05 22.1 0.0 0.00062 19.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME83858.1 - 0.0022 18.4 0.0 0.0057 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME83858.1 - 0.046 14.2 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EME83858.1 - 0.083 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_1 PF00583.19 EME83859.1 - 2.1e-07 30.8 0.1 4.4e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME83859.1 - 0.0045 17.1 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME83859.1 - 0.07 13.0 0.1 0.29 11.0 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Nramp PF01566.13 EME83860.1 - 6.6e-86 288.3 15.7 6.6e-86 288.3 10.9 2.0 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein TMEM156 PF15106.1 EME83860.1 - 0.3 10.2 2.4 0.51 9.5 1.6 1.3 1 0 0 1 1 1 0 TMEM156 protein family Shisa PF13908.1 EME83860.1 - 1.6 8.9 4.9 17 5.5 0.2 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Hce2 PF14856.1 EME83862.1 - 1.6e-20 72.7 0.4 1.8e-20 72.6 0.3 1.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Metallophos PF00149.23 EME83863.1 - 2.4e-13 49.9 0.9 4.4e-13 49.0 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME83863.1 - 0.00021 21.1 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Tyrosinase PF00264.15 EME83866.1 - 5.1e-53 180.4 1.4 9.6e-53 179.6 1.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase VWA_2 PF13519.1 EME83868.1 - 8.6e-05 22.7 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EME83868.1 - 0.00045 19.9 0.0 0.0017 18.1 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain SSF PF00474.12 EME83869.1 - 2.7e-10 39.4 12.1 2.7e-10 39.4 8.4 2.0 1 1 0 2 2 2 1 Sodium:solute symporter family Ferric_reduct PF01794.14 EME83870.1 - 1.1e-18 67.5 12.4 1.1e-18 67.5 8.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EME83870.1 - 3.6e-10 39.9 0.0 9.6e-09 35.3 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EME83870.1 - 2.1e-07 30.7 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EME83870.1 - 0.00017 22.1 0.0 0.002 18.6 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short PF00106.20 EME83871.1 - 1.9e-28 99.4 0.4 2.2e-28 99.2 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME83871.1 - 8.6e-13 48.3 0.2 9.8e-13 48.1 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME83871.1 - 1.2e-10 41.5 0.5 1.6e-10 41.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME83871.1 - 7.7e-05 22.7 0.2 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EME83871.1 - 0.01 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HEM4 PF02602.10 EME83871.1 - 0.041 13.1 0.4 0.075 12.2 0.3 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD TMEM220 PF15071.1 EME83871.1 - 0.086 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 Transmembrane family 220, helix Methyltransf_25 PF13649.1 EME83871.1 - 0.095 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.4 EME83873.1 - 1.3e-55 187.8 0.0 1.7e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EME83873.1 - 0.045 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.15 EME83875.1 - 1.1e-75 254.8 0.0 1.2e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EME83875.1 - 0.026 13.7 0.0 6.4 5.9 0.0 2.7 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 EME83877.1 - 1.2e-08 34.7 12.2 2.5e-08 33.6 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 EME83878.1 - 3.1e-21 76.3 0.0 4.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME83878.1 - 2.8e-15 55.5 0.1 2.7e-13 48.9 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME83878.1 - 2.2e-10 40.7 0.0 1.4e-09 38.1 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME83878.1 - 1.9e-08 33.6 0.0 1.1e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME83878.1 - 6.6e-08 32.4 0.0 2e-06 27.7 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME83878.1 - 3.3e-07 29.5 0.0 0.0013 17.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME83878.1 - 0.0007 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME83878.1 - 0.026 13.6 0.2 0.065 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EME83878.1 - 0.069 12.0 0.1 0.23 10.3 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EME83878.1 - 0.12 11.4 0.2 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EME83878.1 - 0.12 10.7 1.8 0.39 9.1 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 EME83878.1 - 3.6 7.3 11.3 9.3 5.9 0.7 4.3 4 1 0 4 4 4 0 FAD-NAD(P)-binding DUF2606 PF10794.4 EME83879.1 - 0.14 11.6 0.7 0.21 10.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) DUF3429 PF11911.3 EME83880.1 - 1.7e-39 135.0 8.3 2e-39 134.7 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) bZIP_2 PF07716.10 EME83882.1 - 1.5e-11 43.9 14.0 1.5e-11 43.9 9.7 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EME83882.1 - 0.00077 19.3 21.3 0.0014 18.5 10.6 2.8 1 1 1 2 2 2 1 bZIP transcription factor DDE_Tnp_IS240 PF13610.1 EME83882.1 - 0.038 13.9 3.4 0.064 13.2 2.4 1.5 1 0 0 1 1 1 0 DDE domain Tnp_P_element PF12017.3 EME83882.1 - 0.058 12.6 1.9 0.087 12.0 1.3 1.2 1 0 0 1 1 1 0 Transposase protein FlxA PF14282.1 EME83882.1 - 0.068 13.1 10.0 0.11 12.4 6.9 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF2762 PF10960.3 EME83882.1 - 0.08 12.6 3.0 0.15 11.8 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Syntaxin PF00804.20 EME83882.1 - 0.11 12.7 6.5 0.18 11.9 4.5 1.4 1 0 0 1 1 1 0 Syntaxin TSC22 PF01166.13 EME83882.1 - 0.14 12.1 4.5 0.13 12.1 1.9 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 EME83882.1 - 0.14 11.7 6.1 0.18 11.3 4.2 1.1 1 0 0 1 1 1 0 IncA protein Tup_N PF08581.5 EME83882.1 - 0.35 11.0 8.3 0.56 10.4 5.7 1.3 1 0 0 1 1 1 0 Tup N-terminal PRF PF06875.6 EME83882.1 - 0.36 10.0 3.6 0.53 9.4 0.5 2.1 1 1 1 2 2 2 0 Plethodontid receptivity factor PRF XhlA PF10779.4 EME83882.1 - 0.58 10.1 9.5 0.081 12.8 2.9 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Atg14 PF10186.4 EME83882.1 - 1.1 8.1 12.0 1.4 7.8 8.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EME83882.1 - 2.9 8.2 11.5 2.5 8.4 6.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) 2OG-FeII_Oxy PF03171.15 EME83883.1 - 0.0025 18.0 0.1 0.0053 17.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dioxygenase_C PF00775.16 EME83885.1 - 1.3e-08 34.2 0.0 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase MG1 PF11974.3 EME83885.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.8 1 1 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain PRELI PF04707.9 EME83886.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 PRELI-like family TP2 PF01254.13 EME83887.1 - 8 6.8 10.1 85 3.4 6.7 2.3 1 1 0 1 1 1 0 Nuclear transition protein 2 DEAD PF00270.24 EME83888.1 - 6.6e-20 71.2 0.0 2e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME83888.1 - 3.5e-17 62.0 0.0 3.5e-14 52.4 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 EME83888.1 - 0.00099 17.9 0.1 0.0015 17.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ecm33 PF12454.3 EME83891.1 - 9.7e-13 47.7 0.1 3.2e-12 46.0 0.1 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EME83891.1 - 3.8e-06 26.8 4.3 0.44 10.5 0.0 4.5 1 1 3 4 4 4 3 Receptor L domain LRR_5 PF13306.1 EME83891.1 - 0.00016 21.3 2.4 0.0043 16.7 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeats (6 copies) CxxCxxCC PF03692.10 EME83893.1 - 0.1 13.0 0.3 0.16 12.4 0.2 1.4 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain Anp1 PF03452.9 EME83894.1 - 2.5e-107 358.0 0.0 3e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Mpp10 PF04006.7 EME83895.1 - 9.7e-88 295.0 75.1 3.2e-87 293.3 52.0 1.7 1 1 0 1 1 1 1 Mpp10 protein Amidohydro_1 PF01979.15 EME83896.1 - 5e-55 187.4 0.9 5.9e-55 187.2 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EME83896.1 - 1.6e-15 57.9 0.1 1.2e-12 48.4 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EME83896.1 - 3.1e-14 53.0 0.1 1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EME83896.1 - 2.3e-10 40.1 0.0 6.1e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EME83896.1 - 0.011 14.6 0.0 0.037 12.9 0.0 1.7 2 0 0 2 2 2 0 Adenosine/AMP deaminase Otopetrin PF03189.8 EME83897.1 - 0.025 13.5 0.6 0.031 13.3 0.4 1.1 1 0 0 1 1 1 0 Otopetrin DUF2895 PF11444.3 EME83897.1 - 0.032 13.4 0.6 0.049 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) SH PF01445.12 EME83897.1 - 0.037 13.6 0.1 0.037 13.6 0.1 2.2 2 1 0 2 2 2 0 Viral small hydrophobic protein DUF4293 PF14126.1 EME83897.1 - 0.098 12.5 6.5 2.5 8.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) NfeD PF01957.13 EME83897.1 - 2.1 8.4 9.5 0.18 11.9 0.6 2.1 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4131 PF13567.1 EME83897.1 - 2.7 7.3 7.2 1.1 8.6 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1772 PF08592.6 EME83897.1 - 2.9 7.5 8.4 0.17 11.6 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Aldo_ket_red PF00248.16 EME83898.1 - 1.7e-42 145.1 0.0 2e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box PF00646.28 EME83900.1 - 0.0092 15.6 0.0 0.036 13.7 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME83900.1 - 0.042 13.5 0.2 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 F-box-like PHD PF00628.24 EME83902.1 - 0.014 15.0 4.2 0.014 15.0 2.9 1.8 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.1 EME83902.1 - 0.48 10.5 2.8 0.61 10.2 1.1 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF1253 PF06862.7 EME83903.1 - 2.6e-151 504.0 0.0 3.3e-151 503.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MitMem_reg PF13012.1 EME83904.1 - 9.1e-19 67.6 1.5 1.4e-18 66.9 1.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EME83904.1 - 1.9e-17 63.0 0.0 3.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-C4H2 PF10146.4 EME83904.1 - 0.11 12.4 2.1 0.14 12.1 0.3 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein DNase_NucA_NucB PF14040.1 EME83905.1 - 4.7e-14 52.5 0.8 1e-13 51.4 0.6 1.6 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB TPR_12 PF13424.1 EME83907.1 - 1.6e-05 24.7 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME83907.1 - 2.9e-05 23.8 0.1 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat MFS_1 PF07690.11 EME83908.1 - 3.4e-31 108.2 30.9 3.4e-31 108.2 21.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EME83908.1 - 8.7 5.0 37.7 0.072 11.9 10.5 2.9 2 1 0 2 2 2 0 Acyltransferase family zf-MYND PF01753.13 EME83909.1 - 8.5e-10 38.3 7.3 8.5e-10 38.3 5.1 1.6 2 0 0 2 2 2 1 MYND finger WH2 PF02205.15 EME83909.1 - 0.0008 18.9 0.1 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 WH2 motif zf-Mss51 PF13824.1 EME83909.1 - 0.023 14.5 2.0 0.054 13.3 1.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SKG6 PF08693.5 EME83911.1 - 0.0034 16.6 0.2 0.0071 15.6 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3827 PF12877.2 EME83911.1 - 0.017 13.2 0.0 0.027 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Syndecan PF01034.15 EME83911.1 - 0.032 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DnaJ PF00226.26 EME83913.1 - 0.001 18.7 0.1 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SelP_N PF04592.9 EME83913.1 - 0.033 13.5 1.0 0.068 12.5 0.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region G-patch PF01585.18 EME83915.1 - 2.4e-10 40.0 2.6 4.4e-10 39.1 1.8 1.4 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EME83915.1 - 0.0001 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME83915.1 - 0.00063 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83915.1 - 0.0058 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EME83915.1 - 0.062 13.1 1.0 0.14 11.9 0.7 1.7 1 1 0 1 1 1 0 DExH-box splicing factor binding site DUF1712 PF08217.6 EME83916.1 - 3.3e-17 61.9 0.0 1.1e-15 56.9 0.0 2.9 3 1 0 3 3 3 1 Fungal domain of unknown function (DUF1712) UCR_14kD PF02271.11 EME83917.1 - 1.2e-45 153.5 0.2 1.4e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EME83918.1 - 1.1e-67 223.8 0.3 1.9e-24 85.1 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein IKI3 PF04762.7 EME83921.1 - 0 1018.3 0.0 0 1018.1 0.0 1.0 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.15 EME83921.1 - 0.18 11.4 6.0 0.7 9.4 0.2 3.3 1 1 2 3 3 3 0 Region in Clathrin and VPS TPR_11 PF13414.1 EME83925.1 - 2.9e-05 23.6 2.9 0.0064 16.1 0.9 2.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EME83925.1 - 0.00024 20.7 4.0 0.6 10.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME83925.1 - 0.0016 18.2 1.3 0.96 9.4 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME83925.1 - 0.0038 17.5 0.9 1 9.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME83925.1 - 0.02 14.4 3.3 0.73 9.5 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME83925.1 - 0.026 14.9 1.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME83925.1 - 0.045 14.4 2.7 6.2 7.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME83925.1 - 0.12 13.0 1.8 11 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EME83926.1 - 5.1e-36 124.3 0.0 6.1e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Nuc_sug_transp PF04142.10 EME83927.1 - 5.8e-74 248.2 5.4 9e-74 247.6 3.7 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EME83927.1 - 6.5e-08 32.6 20.4 3.1e-05 24.0 1.6 2.6 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EME83927.1 - 2.7e-07 30.3 21.9 0.00064 19.3 8.9 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EME83927.1 - 1.1e-06 28.8 17.1 5e-06 26.6 2.0 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UAA PF08449.6 EME83927.1 - 0.00013 20.9 14.0 0.0013 17.7 9.7 2.0 1 1 0 1 1 1 1 UAA transporter family Sugar_transport PF06800.7 EME83927.1 - 0.0074 15.3 2.0 0.0074 15.3 1.4 2.5 3 0 0 3 3 3 1 Sugar transport protein Trp_oprn_chp PF09534.5 EME83927.1 - 2.2 7.8 7.9 3.1 7.3 0.1 3.3 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF202 PF02656.10 EME83927.1 - 4.9 7.4 8.9 0.81 9.9 0.1 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Sec63 PF02889.11 EME83928.1 - 1.6e-50 172.1 0.0 2.3e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EME83928.1 - 2.9e-26 91.9 0.0 1e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EME83928.1 - 2.7e-08 33.8 0.0 6.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME83928.1 - 1.7e-07 31.0 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME83928.1 - 0.023 14.8 0.1 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME83928.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TPR_MLP1_2 PF07926.7 EME83929.1 - 2.5e-27 95.2 23.1 2.5e-27 95.2 16.0 17.3 7 5 7 15 15 15 7 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 EME83929.1 - 7.1e-05 22.2 35.1 7.1e-05 22.2 24.3 15.2 6 3 8 14 14 14 4 Mechanosensitive ion channel porin domain TMF_DNA_bd PF12329.3 EME83929.1 - 0.0047 16.6 11.6 0.0047 16.6 8.0 26.1 13 8 13 29 29 29 7 TATA element modulatory factor 1 DNA binding TFIIE_beta PF02186.10 EME83930.1 - 0.011 15.6 0.4 0.07 13.1 0.1 2.2 1 1 1 2 2 2 0 TFIIE beta subunit core domain p450 PF00067.17 EME83933.1 - 1e-43 149.5 0.0 3.1e-43 147.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.1 EME83934.1 - 1e-30 105.8 3.9 2.5e-30 104.6 2.7 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EME83934.1 - 1.1e-10 41.7 0.7 1.9e-06 28.2 0.0 3.4 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 EME83935.1 - 1.1e-30 106.6 23.0 1.1e-30 106.6 16.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME83935.1 - 1.2e-12 47.2 11.1 1.2e-12 47.2 7.7 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EME83935.1 - 1.1e-05 23.8 1.8 1.1e-05 23.8 1.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1614 PF07758.6 EME83935.1 - 0.83 9.3 9.9 1.7 8.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) EMP70 PF02990.11 EME83935.1 - 1.3 7.3 8.1 0.21 10.0 0.9 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 DUF3169 PF11368.3 EME83935.1 - 3 6.9 5.8 3.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) TRI12 PF06609.8 EME83936.1 - 5.9e-07 28.0 0.1 7.6e-07 27.6 0.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME83936.1 - 4e-06 25.8 9.0 4e-06 25.8 6.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HECT PF00632.20 EME83938.1 - 1e-83 281.1 0.0 1.8e-83 280.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MFS_1 PF07690.11 EME83939.1 - 3.9e-24 85.0 33.9 3.9e-24 85.0 23.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S10 PF00450.17 EME83940.1 - 4.3e-78 263.3 0.0 8.8e-78 262.2 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Nitroreductase PF00881.19 EME83942.1 - 4.3e-15 55.9 0.0 5.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family NOC3p PF07540.6 EME83943.1 - 4.1e-33 113.5 3.7 6.1e-33 112.9 0.0 3.1 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 EME83943.1 - 1.5e-27 96.0 0.1 1.5e-27 96.0 0.1 2.0 2 1 1 3 3 3 1 CBF/Mak21 family Borrelia_lipo_2 PF06238.6 EME83943.1 - 1.4 9.0 0.0 1.4 9.0 0.0 2.9 4 0 0 4 4 4 0 Borrelia burgdorferi BBR25 lipoprotein UPF0113 PF03657.8 EME83944.1 - 5.7e-09 35.8 0.0 1.2e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) HhH-GPD PF00730.20 EME83945.1 - 1.1e-14 54.6 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 EME83945.1 - 0.019 15.2 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) CHD5 PF04420.9 EME83946.1 - 4.9e-52 175.8 2.2 5.9e-52 175.5 1.5 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF904 PF06005.7 EME83946.1 - 0.092 13.0 4.4 0.29 11.4 3.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) HALZ PF02183.13 EME83946.1 - 0.15 11.7 3.5 2.3 8.0 0.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 EME83946.1 - 4.8 6.7 8.6 2.3 7.7 3.8 2.1 2 1 0 2 2 2 0 Septum formation initiator PRP1_N PF06424.7 EME83946.1 - 5.8 7.2 7.9 1.2 9.4 1.5 2.0 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal CTP_transf_2 PF01467.21 EME83947.1 - 1.4e-13 51.1 0.1 2.9e-11 43.6 0.0 2.8 2 1 0 2 2 2 2 Cytidylyltransferase 2OG-FeII_Oxy_3 PF13640.1 EME83948.1 - 2.4e-05 24.7 0.0 4.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EME83948.1 - 0.00011 22.4 0.0 0.00025 21.2 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EME83949.1 - 3.2e-27 95.3 0.0 5.6e-27 94.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME83949.1 - 1.4e-13 50.5 0.2 2.8e-12 46.2 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EME83949.1 - 3.6e-05 22.9 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EME83949.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EME83949.1 - 0.059 13.0 3.3 0.051 13.2 0.5 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cys_Met_Meta_PP PF01053.15 EME83950.1 - 9.6e-134 445.4 0.0 1.2e-133 445.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.1 EME83950.1 - 1.4e-28 99.3 0.4 6.6e-28 97.2 0.1 2.3 3 0 0 3 3 3 1 CoA binding domain DegT_DnrJ_EryC1 PF01041.12 EME83950.1 - 1.7e-08 33.9 0.0 3.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EME83950.1 - 3e-06 26.2 0.0 5.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME83950.1 - 8.5e-06 25.1 0.0 2.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EME83950.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CoA_binding PF02629.14 EME83950.1 - 0.00025 21.4 0.0 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain GDC-P PF02347.11 EME83950.1 - 0.00081 18.1 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Cupin_2 PF07883.6 EME83950.1 - 0.006 16.0 0.3 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Cupin domain DUF4096 PF13340.1 EME83950.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) SHMT PF00464.14 EME83950.1 - 0.14 10.4 0.1 0.74 8.1 0.0 1.9 2 0 0 2 2 2 0 Serine hydroxymethyltransferase DUF2408 PF10303.4 EME83951.1 - 2.2e-36 124.9 15.2 1.7e-15 57.2 5.1 6.0 3 1 1 5 5 5 4 Protein of unknown function (DUF2408) DHC PF09626.5 EME83951.1 - 0.063 13.9 0.4 0.15 12.7 0.1 1.7 2 0 0 2 2 2 0 Dihaem cytochrome c Ribosomal_60s PF00428.14 EME83952.1 - 2.4e-25 88.7 10.7 3.2e-25 88.3 7.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein PT-VENN PF04829.8 EME83952.1 - 9 5.9 13.1 15 5.2 8.6 1.8 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif SOG2 PF10428.4 EME83953.1 - 9e-30 103.7 3.3 9e-30 103.7 2.3 2.5 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 EME83953.1 - 9.6e-13 47.4 1.6 6.5e-07 28.8 0.0 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME83953.1 - 4e-10 39.3 2.0 9e-08 31.7 0.2 3.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EME83953.1 - 1.8e-08 33.2 0.8 0.44 10.7 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EME83953.1 - 4.7e-05 22.9 0.1 6.2 7.4 0.1 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EME83953.1 - 0.1 12.7 1.6 5.9 7.2 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat BPL_LplA_LipB PF03099.14 EME83954.1 - 1.9e-10 40.8 0.0 4.5e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family LtrA PF06772.6 EME83955.1 - 1.2e-06 27.7 2.0 1.7e-06 27.1 1.4 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) ZZ PF00569.12 EME83955.1 - 0.0017 17.8 8.5 0.0017 17.8 5.9 3.6 3 0 0 3 3 3 2 Zinc finger, ZZ type DUF3826 PF12875.2 EME83955.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF3702 PF12486.3 EME83955.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 ImpA domain protein HET PF06985.6 EME83958.1 - 1.8e-26 92.9 0.0 3.1e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytomega_US3 PF05963.6 EME83958.1 - 0.12 11.6 0.0 0.33 10.2 0.0 1.7 1 0 0 1 1 1 0 Cytomegalovirus US3 protein Sugar_tr PF00083.19 EME83959.1 - 3.4e-75 253.3 18.0 3.9e-75 253.1 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME83959.1 - 9.9e-17 60.6 24.8 9.9e-17 60.6 17.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EME83959.1 - 5.3e-07 28.3 2.8 5.3e-07 28.3 1.9 3.6 3 1 0 4 4 4 2 MFS/sugar transport protein OapA PF04225.7 EME83959.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain RRM_1 PF00076.17 EME83963.1 - 2.1e-14 52.8 0.0 4.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME83963.1 - 6.9e-11 41.9 0.0 1.8e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME83963.1 - 1.4e-06 28.0 0.1 3.3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME83963.1 - 0.058 13.1 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif EB1_binding PF05937.6 EME83964.1 - 0.0023 18.3 1.9 0.0029 18.0 1.3 1.1 1 0 0 1 1 1 1 EB-1 Binding Domain MbeD_MobD PF04899.7 EME83964.1 - 0.17 11.7 1.5 0.61 10.0 0.1 2.1 2 0 0 2 2 2 0 MbeD/MobD like Creb_binding PF09030.5 EME83964.1 - 0.37 10.9 4.9 0.44 10.7 2.0 1.8 1 1 1 2 2 2 0 Creb binding Med3 PF11593.3 EME83964.1 - 0.71 9.0 5.0 0.88 8.7 3.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UBA PF00627.26 EME83965.1 - 4.9e-06 26.2 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.15 EME83965.1 - 3.7e-05 23.6 0.0 8.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_3 PF09288.5 EME83965.1 - 0.0032 17.0 0.9 0.087 12.4 0.0 2.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain zf-C2H2_2 PF12756.2 EME83965.1 - 0.0037 17.3 0.2 0.0037 17.3 0.1 1.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Katanin_con80 PF13925.1 EME83965.1 - 0.041 13.6 3.6 0.058 13.1 0.0 2.3 2 0 0 2 2 2 0 con80 domain of Katanin zf-DBF PF07535.7 EME83965.1 - 0.074 12.7 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 DBF zinc finger Atg14 PF10186.4 EME83965.1 - 1.7 7.4 17.5 2.9 6.7 12.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SOBP PF15279.1 EME83965.1 - 4 7.7 8.6 4.9 7.4 5.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.5 EME83965.1 - 7 4.9 6.4 7.6 4.8 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Motile_Sperm PF00635.21 EME83966.1 - 1.6e-24 85.5 0.1 3.6e-24 84.5 0.0 1.6 1 1 1 2 2 2 1 MSP (Major sperm protein) domain Pilin PF00114.14 EME83966.1 - 0.029 15.0 1.5 4 8.1 0.0 2.5 2 0 0 2 2 2 0 Pilin (bacterial filament) HTH_3 PF01381.17 EME83966.1 - 0.087 12.6 1.2 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix T2SM PF04612.7 EME83966.1 - 1.3 8.7 5.1 0.57 9.9 0.8 2.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M 4F5 PF04419.9 EME83967.1 - 3.5e-08 34.0 12.9 3.5e-08 34.0 8.9 1.5 1 1 0 1 1 1 1 4F5 protein family RepB PF07506.6 EME83967.1 - 0.25 11.1 3.1 0.26 11.1 2.1 1.0 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF4064 PF13273.1 EME83968.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ELFV_dehydrog PF00208.16 EME83969.1 - 9.4e-86 287.3 4.9 1.2e-85 287.0 3.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EME83969.1 - 9.1e-26 89.9 0.4 7.8e-20 70.7 0.0 2.6 1 1 1 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EME83969.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Acyl_transf_1 PF00698.16 EME83970.1 - 6.1e-18 65.2 0.0 2.7e-12 46.6 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain DLIC PF05783.6 EME83971.1 - 0.66 8.5 2.0 1.4 7.4 1.4 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ycf54 PF10674.4 EME83972.1 - 1.6 8.9 6.7 1.7 8.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) Metallophos_2 PF12850.2 EME83975.1 - 1.1e-12 48.0 0.0 1.4e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 EME83976.1 - 6.2e-26 91.0 0.0 7.5e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EME83976.1 - 0.033 14.0 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain UPF0180 PF03698.8 EME83976.1 - 0.15 11.9 0.1 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) Peptidase_C3G PF12381.3 EME83977.1 - 0.033 13.4 0.1 0.046 12.9 0.1 1.1 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase DUF2690 PF10901.3 EME83977.1 - 0.15 12.0 9.0 0.087 12.8 4.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2690) HEAT PF02985.17 EME83979.1 - 5.3e-08 32.2 2.7 0.044 13.8 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.12 EME83979.1 - 6.5e-08 31.9 0.0 1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME83979.1 - 2.3e-06 26.9 0.0 3.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 EME83979.1 - 0.00038 20.8 0.1 1.4 9.5 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 EME83979.1 - 0.00046 20.4 0.7 0.044 14.0 0.1 3.5 2 1 2 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EME83979.1 - 0.078 12.8 0.0 0.87 9.4 0.0 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RGS PF00615.14 EME83980.1 - 5.6e-12 45.8 0.0 8.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Trypan_PARP PF05887.6 EME83981.1 - 6.7 6.5 9.0 1.6 8.5 3.1 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Dynamin_N PF00350.18 EME83982.1 - 6.3e-30 104.2 0.6 1.6e-29 102.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EME83982.1 - 8.3e-20 70.7 0.7 8.4e-19 67.4 0.1 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EME83982.1 - 0.00018 21.4 0.0 0.0012 18.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME83982.1 - 0.0012 19.3 0.0 0.0063 17.0 0.0 2.3 1 0 0 1 1 1 1 Miro-like protein TMF_TATA_bd PF12325.3 EME83982.1 - 0.0016 18.1 2.4 0.025 14.2 0.1 3.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding AAA_29 PF13555.1 EME83982.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EME83982.1 - 8.5 6.6 12.9 4.2 7.6 2.3 3.4 2 1 0 2 2 2 0 AAA domain SAP PF02037.22 EME83983.1 - 8.1e-06 25.2 0.3 1.3e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 SAP domain DUF1639 PF07797.9 EME83984.1 - 8.3 5.8 7.9 18 4.8 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1639) TauD PF02668.11 EME83985.1 - 7.3e-32 111.0 0.0 9.4e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Orn_Arg_deC_N PF02784.11 EME83986.1 - 1.8e-71 240.2 0.0 2.2e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EME83986.1 - 6.1e-29 100.0 0.1 1.1e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MFS_1 PF07690.11 EME83987.1 - 5.3e-36 124.0 21.0 5.3e-36 124.0 14.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME83987.1 - 1.2e-15 57.0 6.5 1.2e-15 57.0 4.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EME83987.1 - 9.6e-05 20.7 1.9 0.00014 20.2 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EME83987.1 - 0.004 15.2 0.7 0.0065 14.5 0.0 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EME83987.1 - 0.0051 14.9 1.3 0.0076 14.4 0.9 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector IucA_IucC PF04183.7 EME83988.1 - 1.2e-23 83.6 0.4 3e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 IucA / IucC family FhuF PF06276.7 EME83988.1 - 1.1e-22 80.7 0.0 1.9e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Ammonium_transp PF00909.16 EME83989.1 - 7.3e-66 222.2 24.9 8.3e-66 222.0 17.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Fungal_trans PF04082.13 EME83990.1 - 1.2e-21 76.8 0.0 1.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME83990.1 - 0.0045 16.8 13.0 0.0087 15.9 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoporin_C PF03177.9 EME83992.1 - 1e-63 215.8 17.4 1.4e-63 215.4 12.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EME83992.1 - 1.1e-31 110.0 0.0 1.6e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Hexapep PF00132.19 EME83996.1 - 2e-14 52.3 7.2 2.7e-09 36.1 0.3 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME83996.1 - 1.6e-08 33.9 10.9 2.4e-07 30.1 1.3 3.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Chromo PF00385.19 EME84000.1 - 9.3e-06 25.2 4.0 1.6e-05 24.4 2.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Med18 PF09637.5 EME84001.1 - 1.4e-26 93.5 0.2 3.9e-26 92.0 0.1 1.6 1 1 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EME84002.1 - 3.4e-33 114.9 5.1 4.6e-32 111.3 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) BTB PF00651.26 EME84003.1 - 1.4e-08 34.6 0.0 1.3e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain SPX PF03105.14 EME84003.1 - 0.28 10.9 3.8 0.58 9.8 2.6 1.5 1 0 0 1 1 1 0 SPX domain FlxA PF14282.1 EME84003.1 - 0.56 10.1 9.3 0.84 9.6 4.2 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF680 PF05079.7 EME84003.1 - 0.87 10.1 3.4 1.9 9.0 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF680) TMF_DNA_bd PF12329.3 EME84003.1 - 4.8 7.0 7.0 17 5.2 1.7 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tcp11 PF05794.8 EME84004.1 - 2.3e-76 257.3 0.1 5.3e-76 256.1 0.1 1.5 1 1 0 1 1 1 1 T-complex protein 11 CTP_transf_2 PF01467.21 EME84007.1 - 1.5e-20 73.8 0.0 3.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EME84007.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase PP2C PF00481.16 EME84008.1 - 2.8e-82 275.9 0.0 4.2e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EME84008.1 - 0.00025 20.5 0.0 0.00062 19.2 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C FMN_dh PF01070.13 EME84009.1 - 7e-29 100.7 0.0 2.1e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase zf-nanos PF05741.8 EME84010.1 - 0.094 12.7 1.3 0.15 12.0 0.9 1.5 1 1 0 1 1 1 0 Nanos RNA binding domain MHYT PF03707.11 EME84011.1 - 4.6e-09 36.2 12.4 3e-05 24.0 0.2 4.4 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat 4HBT PF03061.17 EME84014.1 - 0.00063 19.8 0.4 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily WD40 PF00400.27 EME84015.1 - 3.7e-55 181.9 12.6 1.4e-11 43.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME84015.1 - 8.3e-09 34.8 0.1 0.0012 18.2 0.0 4.3 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SH3_9 PF14604.1 EME84015.1 - 0.074 12.6 2.1 0.12 11.9 0.1 2.3 2 0 0 2 2 2 0 Variant SH3 domain DUF1183 PF06682.7 EME84018.1 - 1.4 8.4 7.5 1.9 7.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Aminotran_4 PF01063.14 EME84022.1 - 4e-22 78.8 0.0 6.7e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Alba PF01918.16 EME84023.1 - 4.3e-05 23.0 0.3 8.6e-05 22.0 0.2 1.5 1 0 0 1 1 1 1 Alba GUB_WAK_bind PF13947.1 EME84023.1 - 0.047 14.2 0.1 3.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Wall-associated receptor kinase galacturonan-binding IR1-M PF12185.3 EME84023.1 - 2.9 7.6 5.2 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain AFG1_ATPase PF03969.11 EME84026.1 - 1.4e-57 195.1 2.0 1.3e-26 93.3 0.0 5.1 4 1 1 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.9 EME84026.1 - 0.00055 19.6 0.0 0.0014 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME84026.1 - 0.00074 19.5 0.5 0.0042 17.0 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME84026.1 - 0.0018 18.4 0.0 0.0053 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EME84026.1 - 0.0064 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EME84026.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EME84026.1 - 0.13 11.7 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EME84026.1 - 0.17 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EME84026.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Torsin rRNA_proc-arch PF13234.1 EME84027.1 - 5.9e-97 324.0 0.1 1.3e-96 322.9 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EME84027.1 - 4.4e-66 221.5 1.8 9.5e-66 220.4 1.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EME84027.1 - 5.6e-22 78.0 0.0 2e-21 76.2 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME84027.1 - 1.8e-07 30.8 0.0 4.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME84027.1 - 0.0019 18.0 0.1 0.026 14.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF677 PF05055.7 EME84027.1 - 0.0045 15.6 0.2 0.012 14.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF677) T2SE PF00437.15 EME84027.1 - 0.0063 15.4 0.0 0.024 13.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein PP_M1 PF03012.9 EME84029.1 - 0.019 14.3 0.4 0.024 14.0 0.2 1.1 1 0 0 1 1 1 0 Phosphoprotein GEMIN8 PF15348.1 EME84029.1 - 0.056 13.4 3.4 0.079 12.9 2.4 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CDC45 PF02724.9 EME84029.1 - 0.17 9.9 1.4 0.14 10.1 1.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EME84029.1 - 0.22 9.4 7.6 0.22 9.4 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EME84029.1 - 0.39 9.6 5.2 0.47 9.4 3.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 EME84029.1 - 0.41 9.8 6.9 0.43 9.8 4.8 1.1 1 0 0 1 1 1 0 SDA1 BTV_NS2 PF04514.7 EME84029.1 - 0.6 8.9 5.5 0.76 8.5 3.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NOA36 PF06524.7 EME84029.1 - 0.69 9.1 6.2 0.83 8.8 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EME84029.1 - 0.7 8.3 8.7 0.89 7.9 6.0 1.1 1 0 0 1 1 1 0 Daxx Family zf-H2C2_2 PF13465.1 EME84031.1 - 6.3e-14 51.4 7.9 5.4e-08 32.7 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EME84031.1 - 9.3e-11 41.4 12.2 5.5e-06 26.4 1.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME84031.1 - 1.5e-10 40.6 12.9 2.6e-05 24.2 1.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME84031.1 - 9e-07 28.8 4.7 0.077 13.1 0.2 4.7 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME84031.1 - 0.00027 21.0 4.4 0.017 15.3 0.2 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EME84031.1 - 0.063 13.5 0.4 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 EME84031.1 - 0.44 10.3 4.1 1.5 8.6 0.7 2.6 1 1 1 2 2 2 0 BED zinc finger Menin PF05053.8 EME84031.1 - 2.3 6.3 5.1 4 5.4 3.5 1.3 1 0 0 1 1 1 0 Menin Zn_clus PF00172.13 EME84032.1 - 8.6e-09 35.1 11.5 8.6e-09 35.1 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1d PF00750.14 EME84033.1 - 1.2e-80 271.0 4.1 1.1e-44 152.7 3.5 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EME84033.1 - 2e-22 79.3 0.8 8e-22 77.4 0.1 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EME84033.1 - 6.1e-08 33.0 0.1 2.1e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain ATPgrasp_Ter PF15632.1 EME84033.1 - 0.0072 15.1 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon NinG PF05766.7 EME84035.1 - 0.072 12.8 2.1 0.16 11.7 1.4 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Abhydrolase_3 PF07859.8 EME84036.1 - 2.3e-31 109.0 0.0 3.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EME84036.1 - 1.4e-09 37.1 0.0 1.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EME84036.1 - 0.015 15.0 0.1 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EME84036.1 - 0.031 14.4 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 EME84036.1 - 0.046 12.9 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.3 EME84036.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BAAT_C PF08840.6 EME84036.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal ASFV_J13L PF05568.6 EME84040.1 - 0.15 11.5 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Cellulase PF00150.13 EME84041.1 - 1e-05 24.9 0.4 1.6e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PUF PF00806.14 EME84042.1 - 2.3e-28 96.0 0.0 1.2e-05 24.5 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EME84042.1 - 2.1e-12 46.4 0.0 4.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME84042.1 - 2.5e-08 33.6 0.1 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84042.1 - 3.1e-06 27.0 0.0 7.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2811 PF10929.3 EME84042.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) MFS_1 PF07690.11 EME84043.1 - 1.8e-35 122.2 30.5 1.8e-30 105.8 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME84043.1 - 8.4e-13 47.6 2.8 8.4e-13 47.6 1.9 2.7 2 2 1 3 3 3 1 Sugar (and other) transporter ATG22 PF11700.3 EME84043.1 - 1.1e-06 27.3 22.1 0.017 13.5 0.5 3.0 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like TRI12 PF06609.8 EME84043.1 - 0.00064 18.0 0.3 0.0014 16.8 0.2 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EME84043.1 - 0.032 12.3 5.9 0.12 10.4 0.5 2.5 2 0 0 2 2 2 0 Transmembrane secretion effector UPF0542 PF15086.1 EME84043.1 - 0.038 13.7 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 MRAP PF15183.1 EME84043.1 - 0.066 12.8 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Rifin_STEVOR PF02009.11 EME84044.1 - 0.0024 17.5 0.3 0.0029 17.3 0.2 1.1 1 0 0 1 1 1 1 Rifin/stevor family DUF4083 PF13314.1 EME84044.1 - 0.01 15.6 1.2 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF4381 PF14316.1 EME84044.1 - 0.014 15.4 0.3 0.022 14.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) UDPGT PF00201.13 EME84044.1 - 0.016 13.7 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Herpes_glycop PF01528.11 EME84044.1 - 0.023 13.4 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M P12 PF12669.2 EME84044.1 - 0.031 14.4 0.6 0.043 14.0 0.4 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF2029 PF09594.5 EME84044.1 - 0.044 13.2 0.0 0.052 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF2500 PF10694.4 EME84044.1 - 0.073 13.0 0.6 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF202 PF02656.10 EME84044.1 - 0.12 12.6 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) CytB6-F_Fe-S PF08802.5 EME84045.1 - 5.3 7.1 6.5 0.35 10.9 0.8 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Glyco_transf_90 PF05686.7 EME84046.1 - 5.8e-15 54.8 1.8 7.4e-13 47.9 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 Pro_CA PF00484.14 EME84047.1 - 2.3e-43 147.8 0.0 2.9e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AIG2 PF06094.7 EME84047.1 - 0.12 12.8 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 AIG2-like family YjeF_N PF03853.10 EME84047.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus zf-H2C2_2 PF13465.1 EME84049.1 - 5e-05 23.3 13.0 0.00053 20.1 2.8 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME84049.1 - 0.00022 21.3 15.4 0.37 11.2 0.1 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EME84049.1 - 0.0046 17.1 0.4 0.32 11.2 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EME84049.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type GFA PF04828.9 EME84050.1 - 1.6e-23 82.4 1.0 2.2e-23 82.0 0.7 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EME84050.1 - 0.56 9.7 0.2 0.56 9.7 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EME84050.1 - 0.78 9.4 0.1 0.78 9.4 0.0 3.0 3 0 0 3 3 3 0 Nudix N-terminal Rubredoxin PF00301.15 EME84050.1 - 8.9 6.2 9.4 2.2 8.2 3.0 2.6 2 1 0 2 2 2 0 Rubredoxin DivIC PF04977.10 EME84051.1 - 0.0098 15.3 0.5 0.019 14.4 0.3 1.4 1 0 0 1 1 1 1 Septum formation initiator ATG16 PF08614.6 EME84051.1 - 0.017 14.9 0.9 0.03 14.1 0.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Rad60-SLD PF11976.3 EME84051.1 - 0.058 13.0 0.1 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HalX PF08663.5 EME84052.1 - 0.16 11.9 2.6 1.7 8.7 1.7 2.4 2 0 0 2 2 2 0 HalX domain Ras PF00071.17 EME84053.1 - 5.6e-53 178.6 0.0 6.9e-53 178.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME84053.1 - 4.6e-16 59.3 0.0 9.5e-16 58.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME84053.1 - 3.3e-06 26.4 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.11 EME84054.1 - 7.3e-19 67.6 50.0 1.2e-11 43.9 17.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_B_thumb PF14791.1 EME84056.1 - 1.4e-20 72.6 0.2 2.5e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EME84056.1 - 1.6e-20 72.3 1.5 3.4e-20 71.3 0.4 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EME84056.1 - 7.8e-19 67.7 0.1 2.6e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EME84056.1 - 5.8e-09 36.0 0.1 1.2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EME84056.1 - 0.0038 17.5 0.0 0.0085 16.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 EME84056.1 - 0.033 14.3 0.0 13 6.0 0.0 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix domain MMR_HSR1 PF01926.18 EME84057.1 - 8.7e-15 54.7 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME84057.1 - 0.00043 20.1 0.0 0.048 13.4 0.0 2.4 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EME84057.1 - 0.00052 19.3 0.0 0.0009 18.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EME84057.1 - 0.00095 18.3 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EME84057.1 - 0.02 15.3 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EME84057.1 - 0.022 14.7 0.4 0.043 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EME84057.1 - 0.23 11.7 1.8 0.31 11.3 0.2 2.0 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EME84058.1 - 3.4e-28 99.0 0.0 6.8e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME84058.1 - 1.3e-19 70.7 0.1 1e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME84058.1 - 2.3e-07 30.6 0.0 8.1e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME84058.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase HK PF02110.10 EME84059.1 - 1e-77 260.6 0.5 1.8e-77 259.8 0.3 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EME84059.1 - 1.7e-55 186.9 4.2 2.9e-55 186.1 2.9 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EME84059.1 - 0.00051 19.3 0.1 0.0018 17.5 0.1 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.12 EME84059.1 - 0.0011 18.3 0.3 0.0025 17.1 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate kinase eIF-5_eIF-2B PF01873.12 EME84060.1 - 7.3e-42 141.9 0.0 1.2e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EME84060.1 - 2.3e-24 85.1 1.5 2.3e-24 85.1 1.0 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 EME84060.1 - 0.07 13.0 0.3 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Med22 PF06179.7 EME84061.1 - 1.7e-13 50.5 3.4 2.4e-13 50.0 2.4 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3922 PF13059.1 EME84061.1 - 0.095 12.8 0.2 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) ThiS PF02597.15 EME84061.1 - 0.25 11.8 1.8 1.8 9.0 0.1 2.5 1 1 2 3 3 3 0 ThiS family PEP-utilisers_N PF05524.8 EME84061.1 - 1.6 8.5 5.2 4.3 7.1 3.2 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Amidohydro_2 PF04909.9 EME84062.1 - 9.2e-40 136.9 0.0 1.1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Utp14 PF04615.8 EME84063.1 - 4.4e-153 511.1 68.6 4.4e-153 511.1 47.5 2.4 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EME84064.1 - 1.4e-17 63.3 0.4 1.7e-17 63.0 0.2 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 UQ_con PF00179.21 EME84065.1 - 6e-12 45.1 0.0 1e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like_2 PF13013.1 EME84065.1 - 0.0025 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain RWD PF05773.17 EME84065.1 - 0.0038 17.1 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain Toxin_28 PF08115.6 EME84066.1 - 0.16 11.6 1.8 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 SFI toxin family FGGY_C PF02782.11 EME84068.1 - 1.2e-74 250.2 1.1 2.1e-74 249.4 0.7 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EME84068.1 - 3.2e-60 203.5 0.0 4.5e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain dsDNA_bind PF01984.15 EME84069.1 - 0.0085 16.0 6.8 0.01 15.8 4.7 1.3 1 1 0 1 1 1 1 Double-stranded DNA-binding domain CorA PF01544.13 EME84069.1 - 0.011 14.7 0.2 0.012 14.6 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AIP3 PF03915.8 EME84069.1 - 0.096 11.5 1.0 0.093 11.6 0.7 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF2203 PF09969.4 EME84069.1 - 0.097 12.9 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HSBP1 PF06825.7 EME84069.1 - 0.1 12.1 8.3 0.21 11.2 5.7 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 FdhE PF04216.7 EME84069.1 - 0.17 11.5 0.9 0.2 11.3 0.6 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF454 PF04304.8 EME84071.1 - 0.18 11.8 2.5 1.6 8.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Bax1-I PF01027.15 EME84071.1 - 0.98 8.9 8.8 2.7 7.5 6.1 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3180 PF11377.3 EME84071.1 - 8.5 6.2 9.5 4.7 7.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Nse4_C PF08743.5 EME84072.1 - 2.4e-31 107.5 0.0 6.3e-31 106.2 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EME84072.1 - 3.6e-14 52.3 0.4 1e-13 50.8 0.3 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE PI3Ka PF00613.15 EME84073.1 - 1.3e-51 174.4 0.4 1.9e-51 173.8 0.3 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EME84073.1 - 1.3e-42 145.8 0.0 4.5e-41 140.8 0.0 2.9 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EME84073.1 - 2.4e-28 98.7 0.1 4.5e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HGTP_anticodon PF03129.15 EME84074.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain MR_MLE_C PF13378.1 EME84075.1 - 3.7e-31 107.3 0.0 1.4e-30 105.5 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EME84075.1 - 1.9e-21 76.2 0.0 3.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EME84075.1 - 1.8e-09 38.0 0.0 4.8e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain adh_short PF00106.20 EME84079.1 - 4.2e-29 101.6 0.1 7e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84079.1 - 6.1e-22 78.5 0.0 7.6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84079.1 - 3.6e-12 46.3 0.4 1.9e-11 43.9 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EME84079.1 - 0.00067 19.1 0.1 0.00092 18.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME84079.1 - 0.003 17.5 0.2 0.0082 16.1 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EME84079.1 - 0.0074 16.0 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_transf_5 PF08323.6 EME84079.1 - 0.014 14.9 0.0 0.11 11.9 0.0 2.2 2 1 1 3 3 3 0 Starch synthase catalytic domain MFS_1 PF07690.11 EME84080.1 - 6.7e-37 127.0 18.9 6.7e-37 127.0 13.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Lectin_leg-like PF03388.8 EME84081.1 - 3.8e-72 242.1 0.1 4.9e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EME84081.1 - 0.00044 19.6 0.1 0.0026 17.1 0.1 2.0 1 1 0 1 1 1 1 Legume lectin domain ATG27 PF09451.5 EME84081.1 - 0.027 13.7 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 ThiF PF00899.16 EME84082.1 - 1.5e-34 118.7 0.0 2.6e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Peptidase_A25 PF03418.9 EME84082.1 - 0.055 12.1 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Germination protease TrkA_N PF02254.13 EME84082.1 - 0.066 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain COesterase PF00135.23 EME84083.1 - 7.7e-104 348.3 0.0 9.3e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EME84083.1 - 0.00063 19.0 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EME84083.1 - 0.00095 18.7 0.3 0.0066 16.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_transf_8 PF01501.15 EME84085.1 - 1e-21 77.3 0.0 1.9e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_16 PF10294.4 EME84086.1 - 1.1e-24 86.7 0.0 1.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EME84086.1 - 1.5e-08 34.1 0.0 2.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EME84086.1 - 4.5e-07 30.4 0.0 7.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME84086.1 - 5e-06 25.8 0.0 7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EME84086.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME84086.1 - 0.00042 19.9 0.0 0.00071 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME84086.1 - 0.0013 19.2 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EME84086.1 - 0.0024 17.4 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein ADH_zinc_N PF00107.21 EME84086.1 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EME84086.1 - 0.0081 15.8 0.0 0.018 14.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME84086.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EME84086.1 - 0.034 13.1 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EME84086.1 - 0.084 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.12 EME84086.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.4 1 1 0 1 1 1 0 Spermine/spermidine synthase Methyltransf_25 PF13649.1 EME84086.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EME84086.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_3 PF07859.8 EME84087.1 - 4e-20 72.2 0.0 6e-19 68.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME84087.1 - 1.6e-14 53.6 0.0 3.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME84087.1 - 1.6e-11 44.1 0.0 2.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME84087.1 - 2.6e-10 40.5 0.1 3.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EME84087.1 - 4.5e-06 25.6 0.0 7.2e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EME84087.1 - 7.5e-06 25.0 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 EME84087.1 - 3.5e-05 22.4 0.0 0.08 11.4 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EME84087.1 - 0.00011 21.7 0.0 0.058 12.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 EME84087.1 - 0.00021 20.8 0.0 0.00092 18.7 0.0 2.1 1 1 1 2 2 2 1 Putative esterase DLH PF01738.13 EME84087.1 - 0.00053 19.3 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family COesterase PF00135.23 EME84087.1 - 0.00056 18.7 0.0 0.0013 17.5 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.15 EME84087.1 - 0.11 12.0 0.0 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EME84087.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Epimerase PF01370.16 EME84088.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPSase_L_D2 PF02786.12 EME84090.1 - 8.9e-72 240.7 0.0 1.3e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EME84090.1 - 1.5e-35 121.3 0.0 5.1e-35 119.6 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EME84090.1 - 2.2e-34 117.8 0.0 4.8e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EME84090.1 - 1.3e-17 64.1 0.0 2.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EME84090.1 - 2e-17 62.5 2.2 4.6e-17 61.4 1.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EME84090.1 - 2.8e-11 42.7 0.0 5.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EME84090.1 - 7e-09 35.3 0.0 1.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EME84090.1 - 1.1e-06 28.2 0.0 0.0078 15.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EME84090.1 - 0.00043 20.1 0.0 0.00095 19.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EME84090.1 - 0.0022 18.3 0.0 0.74 10.1 0.0 3.0 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 EME84090.1 - 0.007 15.7 0.1 1.4 8.1 0.2 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RimK PF08443.6 EME84090.1 - 0.0079 15.6 0.0 0.034 13.6 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EME84090.1 - 0.013 15.1 0.5 0.033 13.8 0.1 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein HlyD_2 PF12700.2 EME84090.1 - 0.026 13.6 0.2 2.5 7.1 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Toxin_59 PF15537.1 EME84090.1 - 0.044 13.8 0.0 0.78 9.8 0.0 2.7 2 0 0 2 2 2 0 Putative toxin 59 bZIP_1 PF00170.16 EME84091.1 - 0.015 15.2 1.6 0.038 13.9 1.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF1021 PF06257.6 EME84091.1 - 0.19 11.4 1.7 3.3 7.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1021) DUF2413 PF10310.4 EME84091.1 - 0.24 10.1 7.7 0.28 9.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Bromodomain PF00439.20 EME84092.1 - 4.4e-06 26.5 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Collagen PF01391.13 EME84093.1 - 0.0021 17.5 33.1 5.1e+02 0.3 22.9 2.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) CBFD_NFYB_HMF PF00808.18 EME84095.1 - 9.5e-10 38.4 1.0 2.4e-09 37.1 0.7 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME84095.1 - 0.012 15.7 0.1 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Aldedh PF00171.17 EME84096.1 - 6e-155 516.0 0.3 6.7e-155 515.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1996 PF09362.5 EME84097.1 - 2.4e-59 200.8 1.9 2.4e-59 200.8 1.3 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.13 EME84099.1 - 2.1e-13 49.7 0.0 3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME84099.1 - 2.5e-06 27.2 9.1 5.9e-06 26.0 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EME84100.1 - 8.8e-67 225.8 0.1 5.2e-65 220.0 0.1 2.3 1 1 0 1 1 1 1 Amidase CitX PF03802.9 EME84100.1 - 0.0086 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DUF4350 PF14258.1 EME84100.1 - 0.12 12.6 0.3 0.55 10.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) PAN_4 PF14295.1 EME84102.1 - 0.022 14.4 5.3 0.14 11.8 0.1 2.8 2 0 0 2 2 2 0 PAN domain Zip PF02535.17 EME84103.1 - 1.2e-49 169.0 3.2 1.5e-49 168.7 2.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PrgI PF12666.2 EME84103.1 - 0.33 11.1 7.0 3.7 7.7 0.0 3.5 4 0 0 4 4 4 0 PrgI family protein Ank_2 PF12796.2 EME84104.1 - 2.6e-22 78.9 2.6 1.2e-11 44.8 0.5 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME84104.1 - 6.8e-16 57.1 3.5 0.00064 19.4 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EME84104.1 - 5.4e-14 50.9 0.3 0.00068 19.6 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EME84104.1 - 4.8e-13 49.2 0.7 0.00015 22.1 0.0 4.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME84104.1 - 2.2e-09 37.2 3.4 0.012 15.7 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) ADH_zinc_N_2 PF13602.1 EME84105.1 - 4e-19 69.7 0.0 6.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EME84105.1 - 7.5e-14 51.3 0.0 1.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME84105.1 - 0.00063 19.4 0.0 0.0085 15.8 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Flavin_Reduct PF01613.13 EME84106.1 - 1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EME84106.1 - 0.00057 19.4 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 EME84106.1 - 0.00081 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ada_Zn_binding PF02805.11 EME84107.1 - 3.3e-31 106.6 6.8 5e-31 106.0 4.7 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EME84107.1 - 2.3e-07 30.3 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EME84107.1 - 1.7e-05 24.8 0.3 2.8e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HAD_2 PF13419.1 EME84108.1 - 6.6e-20 72.0 0.0 9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME84108.1 - 2.2e-08 34.7 0.0 1.8e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME84108.1 - 1.4e-07 31.1 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EME84108.1 - 0.0047 17.1 0.0 0.0058 16.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Attachment_P66 PF11263.3 EME84108.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 Hexapep PF00132.19 EME84110.1 - 1.7e-12 46.2 13.9 0.00061 19.1 0.4 5.1 4 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME84110.1 - 0.0097 15.4 14.2 0.24 11.0 0.3 3.4 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF3425 PF11905.3 EME84111.1 - 1.3e-24 86.6 1.9 2.6e-24 85.6 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EME84111.1 - 0.0076 16.1 3.8 0.0076 16.1 2.7 2.5 3 0 0 3 3 3 1 bZIP transcription factor DUF904 PF06005.7 EME84111.1 - 0.14 12.4 1.2 4.5 7.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) LRR_1 PF00560.28 EME84113.1 - 4.2e-08 32.1 0.7 0.26 11.4 0.1 3.6 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.1 EME84113.1 - 5.9e-08 31.9 3.6 0.48 10.6 0.0 4.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.1 EME84113.1 - 1.7e-07 30.8 0.9 4.9e-06 26.1 0.7 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EME84113.1 - 2.8e-07 30.0 2.6 0.00085 18.8 1.3 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EME84113.1 - 7.8e-06 25.2 4.0 1.9 9.0 0.0 3.8 3 0 0 3 3 3 3 Leucine rich repeat APH PF01636.18 EME84115.1 - 1.8e-07 31.1 1.3 6e-06 26.1 0.9 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Suc_Fer-like PF06999.7 EME84121.1 - 9.6e-32 110.8 0.0 2e-31 109.7 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Cyclin_N PF00134.18 EME84123.1 - 4.3e-13 48.9 0.0 7.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EME84123.1 - 7.1e-11 42.7 0.0 7.9e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin SET PF00856.23 EME84125.1 - 8.1e-14 52.2 0.0 2.3e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 SET domain Fis1_TPR_C PF14853.1 EME84125.1 - 0.041 13.7 0.2 2.8 7.9 0.2 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EME84125.1 - 0.11 13.0 4.9 3.7 8.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME84125.1 - 0.9 10.3 4.0 0.83 10.4 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME84125.1 - 1.5 8.9 5.2 10 6.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME84125.1 - 1.5 8.4 8.3 1.8 8.2 0.2 3.7 4 0 0 4 4 4 0 TPR repeat Snf7 PF03357.16 EME84126.1 - 1.2e-46 158.2 12.5 1.4e-46 158.0 8.6 1.1 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.3 EME84126.1 - 0.0025 15.2 8.2 0.003 14.9 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4201 PF13870.1 EME84126.1 - 0.0027 17.1 10.5 0.0027 17.1 7.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EME84126.1 - 0.05 12.7 1.7 0.19 10.8 0.5 1.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EME84126.1 - 0.13 11.1 10.9 0.19 10.6 7.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF919 PF06034.6 EME84126.1 - 0.15 11.6 3.1 2.5 7.7 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DASH_Spc19 PF08287.6 EME84126.1 - 0.43 10.1 7.5 1.4 8.4 4.7 2.0 1 1 1 2 2 2 0 Spc19 NPV_P10 PF05531.7 EME84126.1 - 0.65 10.2 8.7 19 5.6 0.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.9 EME84126.1 - 1.5 8.7 20.6 0.15 12.0 6.0 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GrpE PF01025.14 EME84126.1 - 1.6 8.2 11.4 0.78 9.2 5.4 2.1 1 1 0 2 2 2 0 GrpE FliJ PF02050.11 EME84126.1 - 1.8 8.6 16.1 4.7 7.2 11.1 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein DUF1090 PF06476.7 EME84126.1 - 3.6 7.2 10.3 4.6 6.9 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) IncA PF04156.9 EME84126.1 - 3.7 7.0 8.8 28 4.2 4.2 2.3 1 1 1 2 2 2 0 IncA protein DUF4337 PF14235.1 EME84126.1 - 4.7 7.0 9.8 0.55 10.0 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) COG2 PF06148.6 EME84126.1 - 7.4 6.4 7.8 19 5.1 2.9 2.6 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_1 PF00076.17 EME84127.1 - 2.8e-78 257.5 6.7 3e-19 68.3 0.2 5.6 5 1 1 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84127.1 - 9.3e-54 179.3 0.6 6.5e-15 54.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME84127.1 - 1.7e-37 127.0 0.4 5.7e-08 32.4 0.0 5.9 5 1 1 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EME84127.1 - 2.5e-22 78.3 0.5 9.3e-22 76.4 0.3 2.1 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EME84127.1 - 0.00015 21.4 0.1 13 5.6 0.0 4.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EME84127.1 - 0.0019 17.9 2.4 5.1 6.9 0.1 3.6 3 0 0 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 EME84127.1 - 0.0022 18.1 0.1 0.69 10.1 0.0 3.5 3 0 0 3 3 3 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 EME84127.1 - 0.064 12.7 2.8 7.9 6.0 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain COesterase PF00135.23 EME84129.1 - 3.7e-51 174.4 0.0 4.4e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME84129.1 - 0.0016 18.0 0.3 0.0049 16.4 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.2 EME84130.1 - 1.3e-42 144.0 9.4 2.3e-17 63.0 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EME84130.1 - 2e-32 109.3 11.3 5.3e-07 29.1 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EME84130.1 - 3.3e-30 103.4 16.6 6.2e-08 32.6 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME84130.1 - 6.2e-23 80.7 4.8 1.5e-06 28.5 0.0 5.2 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME84130.1 - 1.4e-22 77.4 2.7 6.9e-05 22.7 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ecl1 PF12855.2 EME84131.1 - 7.3e-13 47.5 0.5 1.5e-12 46.5 0.3 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EME84131.1 - 0.0023 17.7 0.2 0.0051 16.6 0.2 1.5 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 EME84131.1 - 0.0045 16.2 1.8 0.014 14.6 1.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF581) DUF329 PF03884.9 EME84131.1 - 0.02 14.4 2.6 0.046 13.2 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF2256 PF10013.4 EME84131.1 - 1.3 8.8 4.3 0.64 9.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) NicO PF03824.11 EME84132.1 - 4.7e-59 200.0 15.8 4.7e-59 200.0 10.9 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein ketoacyl-synt PF00109.21 EME84133.1 - 5.9e-59 199.5 1.7 5.9e-59 199.5 1.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EME84133.1 - 4.8e-35 119.9 1.5 4.1e-34 116.9 0.5 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EME84133.1 - 4.5e-06 25.8 0.1 1.6e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME84133.1 - 0.00047 19.5 3.4 0.0066 15.8 0.5 3.1 3 1 0 3 3 3 1 Thiolase, C-terminal domain Herpes_US9 PF06072.6 EME84134.1 - 0.2 11.5 0.2 0.45 10.3 0.1 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF1295 PF06966.7 EME84135.1 - 4.9e-43 147.1 0.5 2.8e-41 141.3 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EME84135.1 - 0.0029 17.6 0.3 0.032 14.3 0.0 2.8 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EME84135.1 - 0.013 15.2 0.0 0.059 13.1 0.0 2.0 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EME84135.1 - 0.041 14.0 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Beta-lactamase PF00144.19 EME84136.1 - 3.7e-36 124.8 0.0 5.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Response_reg PF00072.19 EME84137.1 - 3.3e-20 72.1 0.0 4.2e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DRY_EERY PF09750.4 EME84137.1 - 0.19 11.8 8.8 0.38 10.8 6.1 1.4 1 0 0 1 1 1 0 Alternative splicing regulator MIP PF00230.15 EME84139.1 - 8.2e-48 162.8 13.7 1e-47 162.5 9.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein zf-MYND PF01753.13 EME84140.1 - 2.4e-11 43.3 14.5 4.3e-11 42.5 10.1 1.4 1 0 0 1 1 1 1 MYND finger NCD3G PF07562.9 EME84140.1 - 0.37 10.5 10.0 0.23 11.2 1.0 2.4 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ecl1 PF12855.2 EME84140.1 - 0.49 9.7 9.2 1.9 7.8 6.4 2.0 1 1 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 EME84140.1 - 0.51 10.2 5.6 1.6 8.6 3.9 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2HC_2 PF13913.1 EME84140.1 - 6.7 6.5 9.6 0.62 9.7 2.5 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GrpB PF04229.9 EME84141.1 - 4.8e-47 159.7 0.0 5.7e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein TruB_N PF01509.13 EME84142.1 - 2.4e-43 147.8 0.1 1.4e-42 145.3 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DNMT1-RFD PF12047.3 EME84143.1 - 0.037 13.7 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain HSBP1 PF06825.7 EME84144.1 - 0.00025 20.5 0.6 0.00042 19.8 0.0 1.6 2 0 0 2 2 2 1 Heat shock factor binding protein 1 zf-DHHC PF01529.15 EME84146.1 - 1e-40 138.9 0.1 1.9e-40 138.0 0.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Vma12 PF11712.3 EME84146.1 - 0.24 11.1 1.7 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Spt4 PF06093.8 EME84146.1 - 0.37 10.7 3.8 0.73 9.7 2.6 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Yip1 PF04893.12 EME84146.1 - 9.8 5.6 14.3 0.16 11.4 2.9 2.2 2 0 0 2 2 2 0 Yip1 domain F-box-like PF12937.2 EME84148.1 - 0.028 14.1 0.1 0.087 12.5 0.0 1.9 1 0 0 1 1 1 0 F-box-like WD40 PF00400.27 EME84148.1 - 0.049 13.5 0.1 0.49 10.3 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Myosin_tail_1 PF01576.14 EME84150.1 - 0.00023 19.0 8.6 0.00048 18.0 6.0 1.4 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 EME84150.1 - 0.00063 19.3 9.8 0.0017 18.0 6.8 1.6 1 0 0 1 1 1 1 IncA protein CLASP_N PF12348.3 EME84150.1 - 0.0029 16.9 0.0 0.077 12.3 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal DUF4472 PF14739.1 EME84150.1 - 0.011 16.1 2.1 0.044 14.2 1.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) HEAT PF02985.17 EME84150.1 - 0.087 12.9 0.7 20 5.5 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat bZIP_2 PF07716.10 EME84150.1 - 0.21 11.4 8.5 0.15 11.8 0.2 3.3 2 1 1 3 3 3 0 Basic region leucine zipper HALZ PF02183.13 EME84150.1 - 0.69 9.6 4.0 3.2 7.5 1.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper APG6 PF04111.7 EME84150.1 - 1.3 8.0 11.7 0.21 10.6 5.4 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 MFS_1 PF07690.11 EME84151.1 - 1.7e-35 122.3 33.4 1.7e-35 122.3 23.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EME84151.1 - 0.00021 19.4 0.9 0.00021 19.4 0.7 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family OGFr_N PF04664.8 EME84152.1 - 1.1e-31 109.9 0.0 1.3e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region PX PF00787.19 EME84153.1 - 1.2e-16 60.4 0.0 2.9e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EME84153.1 - 2.3e-10 40.1 12.4 9.6e-06 25.0 2.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF2893 PF11459.3 EME84153.1 - 0.026 14.2 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) Peptidase_C10 PF01640.12 EME84153.1 - 0.19 11.4 0.3 0.36 10.5 0.2 1.4 1 0 0 1 1 1 0 Peptidase C10 family BolA PF01722.13 EME84154.1 - 3.7e-17 62.0 0.0 7.2e-17 61.1 0.0 1.5 2 0 0 2 2 2 1 BolA-like protein CBM_21 PF03370.8 EME84157.1 - 3.4e-33 113.9 0.5 6.6e-33 113.0 0.3 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit FAD_binding_2 PF00890.19 EME84158.1 - 3e-44 151.5 0.1 9.6e-38 130.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME84158.1 - 8.5e-07 28.1 0.2 1.8e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME84158.1 - 1.7e-05 23.4 0.5 0.032 12.7 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EME84158.1 - 0.00031 20.6 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME84158.1 - 0.0027 17.6 0.0 0.0086 16.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME84158.1 - 0.0045 16.1 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EME84158.1 - 0.017 14.2 0.1 0.13 11.3 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME84158.1 - 0.023 13.6 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME84158.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EME84158.1 - 0.24 10.1 0.4 0.62 8.8 0.3 1.7 1 0 0 1 1 1 0 Glucose inhibited division protein A NIF PF03031.13 EME84159.1 - 5.7e-53 178.8 0.3 6.4e-53 178.6 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EME84159.1 - 0.0079 16.4 0.1 0.19 11.9 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.1 EME84160.1 - 1e-17 64.7 0.1 1.6e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84160.1 - 4.4e-14 52.7 0.6 8.1e-14 51.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME84160.1 - 0.088 12.4 0.6 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 KR domain Lactococcin_972 PF09683.5 EME84160.1 - 0.18 12.1 2.3 0.5 10.7 0.3 2.5 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) Methyltransf_11 PF08241.7 EME84162.1 - 0.0073 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME84162.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EME84162.1 - 0.022 15.1 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EME84163.1 - 7.7e-71 238.9 0.0 9.8e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DLH PF01738.13 EME84165.1 - 4.8e-16 58.7 0.0 4.4e-07 29.4 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME84165.1 - 2.6e-07 30.5 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME84165.1 - 0.00092 19.1 0.0 0.096 12.5 0.0 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EME84165.1 - 0.0031 17.1 0.0 0.0094 15.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold adh_short_C2 PF13561.1 EME84167.1 - 2.3e-26 93.0 0.0 2.9e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84167.1 - 2.1e-19 70.0 0.0 3.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 EME84167.1 - 0.011 15.7 0.1 0.017 15.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain UPF0004 PF00919.15 EME84167.1 - 0.06 13.1 0.4 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 AAA_6 PF12774.2 EME84167.1 - 0.064 12.7 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 KR PF08659.5 EME84167.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1907 PF08925.6 EME84168.1 - 5.5e-110 366.9 0.0 6.2e-110 366.7 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) Pkinase PF00069.20 EME84170.1 - 1.5e-45 155.3 0.0 2.1e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84170.1 - 4.5e-28 98.0 0.0 2.9e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME84170.1 - 0.064 12.9 0.9 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Arm PF00514.18 EME84171.1 - 4.1e-69 226.2 29.3 8.9e-13 47.5 0.0 11.0 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME84171.1 - 3.3e-25 88.1 12.2 6.4e-06 26.3 0.1 6.9 3 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 EME84171.1 - 1.3e-19 68.4 11.8 0.019 15.0 0.0 9.4 10 0 0 10 10 9 5 HEAT repeat HEAT_EZ PF13513.1 EME84171.1 - 9.9e-14 51.3 14.6 0.052 14.0 0.2 8.0 8 1 1 9 9 8 5 HEAT-like repeat Arm_2 PF04826.8 EME84171.1 - 1.4e-12 47.3 3.4 0.00042 19.4 0.1 3.7 3 1 1 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EME84171.1 - 7.8e-12 44.2 4.2 3e-07 29.1 0.4 2.5 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EME84171.1 - 1.4e-10 39.8 0.1 4.6e-10 38.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EME84171.1 - 1.2e-07 31.1 0.9 0.0055 15.8 0.0 3.7 1 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.2 EME84171.1 - 0.0015 18.3 3.1 3 7.6 0.0 4.4 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.3 EME84171.1 - 0.0017 18.2 1.8 0.53 10.2 0.1 4.4 3 1 2 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 EME84171.1 - 0.013 15.9 5.4 72 4.2 0.0 6.5 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat PUL PF08324.6 EME84171.1 - 0.022 13.5 2.7 0.49 9.1 0.0 3.3 3 1 1 4 4 4 0 PUL domain Vac14_Fab1_bd PF12755.2 EME84171.1 - 0.048 14.0 0.0 2.2 8.7 0.0 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region DUF1981 PF09324.5 EME84171.1 - 0.098 12.1 0.1 9.9 5.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1981) Tropomyosin_1 PF12718.2 EME84173.1 - 3.5e-06 26.9 38.6 0.0015 18.4 13.1 2.8 2 1 1 3 3 3 2 Tropomyosin like TMF_DNA_bd PF12329.3 EME84173.1 - 0.00079 19.1 32.2 0.012 15.4 2.2 3.5 2 1 2 4 4 4 3 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.3 EME84173.1 - 0.0038 14.6 25.6 0.005 14.2 17.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Laminin_I PF06008.9 EME84173.1 - 0.015 14.6 23.7 0.27 10.5 15.6 2.7 1 1 0 1 1 1 0 Laminin Domain I ADIP PF11559.3 EME84173.1 - 0.022 14.6 27.2 0.12 12.2 3.1 2.7 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EME84173.1 - 0.037 13.6 35.1 0.2 11.2 12.8 2.3 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 EME84173.1 - 0.043 13.3 33.9 0.09 12.2 12.6 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Tropomyosin PF00261.15 EME84173.1 - 0.044 12.8 36.7 0.27 10.2 12.5 3.0 1 1 1 2 2 2 0 Tropomyosin Reo_sigmaC PF04582.7 EME84173.1 - 0.054 12.6 1.6 4.7 6.2 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF812 PF05667.6 EME84173.1 - 0.062 11.8 25.4 0.087 11.3 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) YppF PF14178.1 EME84173.1 - 0.076 12.5 0.5 1.6 8.2 0.1 2.5 1 1 1 2 2 2 0 YppF-like protein Spc7 PF08317.6 EME84173.1 - 0.081 11.5 28.1 0.016 13.8 10.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 EME84173.1 - 0.14 11.5 32.2 1.4 8.3 6.5 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4201) KxDL PF10241.4 EME84173.1 - 0.18 11.6 0.3 0.18 11.6 0.2 2.9 3 1 1 4 4 3 0 Uncharacterized conserved protein PilJ PF13675.1 EME84173.1 - 0.19 12.0 12.0 0.11 12.8 1.8 2.8 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF745 PF05335.8 EME84173.1 - 0.2 11.1 22.2 0.17 11.3 7.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.6 EME84173.1 - 0.3 10.9 8.5 1.9 8.4 1.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) EzrA PF06160.7 EME84173.1 - 0.35 9.0 25.4 0.062 11.4 6.9 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Occludin_ELL PF07303.8 EME84173.1 - 0.35 11.6 26.9 0.17 12.5 10.1 3.1 1 1 2 3 3 3 0 Occludin homology domain AAA_13 PF13166.1 EME84173.1 - 0.35 9.2 26.6 0.41 9.0 17.1 1.7 1 1 1 2 2 2 0 AAA domain Erp_C PF06780.6 EME84173.1 - 0.4 10.5 19.5 0.74 9.6 0.5 3.3 1 1 1 2 2 2 0 Erp protein C-terminus MscS_porin PF12795.2 EME84173.1 - 0.43 9.8 25.4 4.2 6.6 5.1 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain WEMBL PF05701.6 EME84173.1 - 0.52 8.7 31.7 6.4 5.1 21.8 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF1796 PF08795.5 EME84173.1 - 0.8 9.3 4.4 0.84 9.2 2.4 1.5 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) CENP-F_leu_zip PF10473.4 EME84173.1 - 1.5 8.6 33.1 1.1 9.0 18.0 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.11 EME84173.1 - 1.8 8.6 31.0 1.1 9.3 9.1 3.5 1 1 3 4 4 4 0 Flagellar FliJ protein APG6 PF04111.7 EME84173.1 - 2.1 7.2 34.0 0.53 9.2 13.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 SlyX PF04102.7 EME84173.1 - 3 8.2 18.5 2.4 8.6 1.4 4.5 2 2 3 5 5 5 0 SlyX Laminin_II PF06009.7 EME84173.1 - 5.1 6.8 17.7 1.7 8.3 4.2 2.4 1 1 1 2 2 2 0 Laminin Domain II AATF-Che1 PF13339.1 EME84173.1 - 6 7.0 25.6 0.15 12.1 6.7 3.2 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor GAS PF13851.1 EME84173.1 - 6.1 5.9 31.7 12 5.0 2.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EME84173.1 - 6.7 6.7 25.0 1.6 8.7 2.5 4.3 1 1 3 4 4 4 0 bZIP transcription factor DUF3186 PF11382.3 EME84173.1 - 7.1 5.6 11.2 3.8 6.5 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) Toxin_36 PF10550.4 EME84174.1 - 0.019 16.0 0.8 0.084 14.0 0.5 2.1 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin CALCOCO1 PF07888.6 EME84174.1 - 0.039 12.2 0.6 0.043 12.1 0.4 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin PF00261.15 EME84176.1 - 0.0027 16.8 5.4 0.0027 16.8 3.7 2.5 2 2 0 2 2 2 1 Tropomyosin Nnf1 PF03980.9 EME84176.1 - 0.2 11.6 7.9 0.84 9.6 0.8 2.7 2 0 0 2 2 2 0 Nnf1 CENP-F_leu_zip PF10473.4 EME84176.1 - 0.22 11.3 19.2 0.28 11.0 4.2 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pox_A_type_inc PF04508.7 EME84176.1 - 0.66 9.9 8.6 4.4 7.3 0.0 4.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Shugoshin_N PF07558.6 EME84176.1 - 1.3 8.7 10.7 3.4 7.4 1.2 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ADIP PF11559.3 EME84176.1 - 3 7.7 24.5 0.16 11.8 7.3 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EME84176.1 - 8.8 6.7 13.0 7.9 6.8 3.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) PP2C PF00481.16 EME84177.1 - 2.2e-37 128.8 0.0 3.2e-31 108.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EME84177.1 - 0.00024 20.5 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Fasciclin PF02469.17 EME84179.1 - 1.9e-52 176.6 2.4 5.4e-29 100.7 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain TMEM89 PF15098.1 EME84179.1 - 0.12 12.4 0.0 17 5.4 0.0 2.2 2 0 0 2 2 2 0 TMEM89 protein family GST_N_3 PF13417.1 EME84180.1 - 3.5e-11 43.1 0.0 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME84180.1 - 1.6e-09 37.6 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME84180.1 - 3.9e-08 33.1 0.0 1.1e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME84180.1 - 6.5e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME84180.1 - 0.00014 22.2 0.0 0.0002 21.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME84180.1 - 0.002 17.9 0.0 0.0054 16.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2-Hacid_dh_C PF02826.14 EME84181.1 - 2.2e-41 140.9 0.0 2.8e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME84181.1 - 3.8e-15 55.5 0.0 4.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME84181.1 - 0.00041 20.2 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DRY_EERY PF09750.4 EME84184.1 - 0.051 13.6 5.4 0.11 12.6 3.7 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Merozoite_SPAM PF07133.6 EME84184.1 - 0.48 10.2 13.7 0.81 9.5 9.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Acyltransferase PF01553.16 EME84185.1 - 6e-13 48.3 0.0 9.8e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ring_hydroxyl_A PF00848.14 EME84185.1 - 0.051 13.2 0.3 0.09 12.4 0.2 1.3 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) zf-C3HC4_2 PF13923.1 EME84186.1 - 1.9e-09 37.3 17.9 4.3e-05 23.4 3.1 2.9 3 1 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME84186.1 - 1.5e-06 27.7 22.6 3.4e-05 23.4 6.6 2.8 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME84186.1 - 3.6e-05 23.5 18.7 0.0091 15.8 4.4 3.5 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.20 EME84186.1 - 0.00014 21.3 17.1 0.018 14.6 5.2 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME84186.1 - 0.00017 21.2 8.7 0.00017 21.2 6.1 2.9 2 1 0 2 2 2 1 zinc-RING finger domain FYVE PF01363.16 EME84186.1 - 0.00024 20.9 7.6 0.00024 20.9 5.3 2.6 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.1 EME84186.1 - 0.021 14.5 12.3 0.051 13.3 3.4 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Erythro_esteras PF05139.9 EME84186.1 - 0.03 13.5 0.4 0.05 12.7 0.3 1.3 1 0 0 1 1 1 0 Erythromycin esterase DUF2259 PF10016.4 EME84186.1 - 0.052 13.2 2.3 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) Rad50_zn_hook PF04423.9 EME84186.1 - 0.057 12.9 9.7 0.19 11.2 0.2 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EME84186.1 - 0.15 12.0 17.7 3.8 7.4 5.7 3.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.16 EME84186.1 - 1 9.2 17.0 1.7 8.5 0.3 3.6 3 1 0 3 3 3 0 IBR domain RTA1 PF04479.8 EME84187.1 - 1.8e-36 125.7 4.2 2.6e-30 105.6 2.1 2.6 1 1 2 3 3 3 2 RTA1 like protein Poxvirus_B22R_C PF13168.1 EME84187.1 - 0.18 11.0 1.8 0.33 10.1 1.2 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal SRP72 PF08492.7 EME84188.1 - 4.8e-16 58.8 10.2 4.8e-16 58.8 7.1 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.1 EME84188.1 - 0.00011 22.7 17.5 0.63 10.7 3.7 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EME84188.1 - 0.0002 21.4 2.7 2.1 8.5 0.2 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EME84188.1 - 0.0023 18.2 20.0 1.6 9.1 0.0 6.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME84188.1 - 0.0045 17.5 25.1 8.7 7.2 0.1 8.7 5 3 4 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME84188.1 - 0.15 12.0 10.6 30 4.8 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat WSC PF01822.14 EME84190.1 - 9e-11 41.5 13.5 2.8e-10 39.9 9.3 1.9 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EME84190.1 - 0.0099 15.1 1.8 0.0099 15.1 1.3 3.1 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EME84190.1 - 0.015 14.9 0.5 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Syndecan domain DUF2500 PF10694.4 EME84190.1 - 0.055 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) MtrF PF09472.5 EME84190.1 - 0.86 8.8 2.9 3.4 6.9 1.1 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) VPEP PF07589.6 EME84190.1 - 2.5 8.1 6.5 7 6.7 4.5 1.8 1 0 0 1 1 1 0 PEP-CTERM motif DUF515 PF04415.7 EME84190.1 - 7.9 4.6 13.7 13 3.9 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Solute_trans_a PF03619.11 EME84193.1 - 4.4e-86 288.6 18.7 5e-86 288.4 13.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Vpu PF00558.14 EME84193.1 - 0.028 13.9 0.9 0.18 11.3 0.6 2.1 2 0 0 2 2 2 0 Vpu protein PrgI PF12666.2 EME84193.1 - 0.033 14.3 0.7 0.033 14.3 0.5 2.9 3 1 1 4 4 4 0 PrgI family protein NfeD PF01957.13 EME84193.1 - 2.5 8.2 10.5 0.18 11.9 1.3 2.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DPM3 PF08285.6 EME84193.1 - 5 7.0 13.0 0.14 12.0 1.3 3.1 2 2 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Frag1 PF10277.4 EME84193.1 - 7.3 6.0 23.9 0.023 14.1 4.9 2.8 2 1 1 3 3 3 0 Frag1/DRAM/Sfk1 family GATase PF00117.23 EME84194.1 - 3.5e-46 157.1 0.1 7.1e-46 156.0 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EME84194.1 - 7.4e-45 151.6 0.0 3.7e-44 149.4 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EME84194.1 - 1.2e-06 28.1 0.1 0.00054 19.4 0.1 2.4 1 1 1 2 2 2 2 Peptidase C26 APH PF01636.18 EME84196.1 - 2.3e-19 70.0 0.1 3e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME84196.1 - 1.3e-06 28.1 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EME84196.1 - 3.4e-05 22.6 0.0 5.7e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 EME84196.1 - 8.1e-05 21.8 0.0 0.0019 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 EME84196.1 - 0.00096 18.5 0.1 0.34 10.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 EME84196.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Tcell_CD4_Cterm PF12104.3 EME84196.1 - 0.87 9.2 2.5 2.9 7.5 0.2 2.3 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region Glyco_hydro_18 PF00704.23 EME84197.1 - 2.5e-11 43.6 0.2 3.1e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BtpA PF03437.10 EME84197.1 - 0.092 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 BtpA family ArfGap PF01412.13 EME84198.1 - 4.8e-32 110.1 0.1 8.7e-32 109.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Fungal_trans PF04082.13 EME84201.1 - 4.1e-23 81.5 0.0 6.1e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC1 PF03109.11 EME84202.1 - 3.9e-32 110.7 0.0 6.3e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family UQ_con PF00179.21 EME84203.1 - 5.8e-48 161.8 0.0 6.5e-48 161.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME84203.1 - 0.00079 19.1 0.0 0.0009 19.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME84203.1 - 0.035 13.9 0.9 0.063 13.1 0.6 1.6 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 EME84204.1 - 1.1e-67 228.3 21.2 1.1e-67 228.3 14.7 1.7 2 0 0 2 2 2 1 Pex19 protein family DUF445 PF04286.7 EME84204.1 - 0.18 11.2 6.8 0.28 10.6 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Cadherin_C PF01049.12 EME84204.1 - 0.97 9.4 9.5 0.2 11.7 1.4 2.7 1 1 1 2 2 2 0 Cadherin cytoplasmic region FliE PF02049.13 EME84204.1 - 1.7 8.7 18.1 0.9 9.6 4.0 4.3 3 1 2 5 5 5 0 Flagellar hook-basal body complex protein FliE MDMPI_N PF11716.3 EME84204.1 - 2.1 8.7 7.6 0.25 11.7 0.8 2.5 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain IR1-M PF12185.3 EME84204.1 - 3.7 7.3 9.3 9.6 6.0 0.0 3.6 4 0 0 4 4 4 0 Nup358/RanBP2 E3 ligase domain Topoisom_I_N PF02919.10 EME84205.1 - 0.12 11.6 1.9 0.18 11.0 1.3 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF1797 PF08796.5 EME84205.1 - 0.36 10.7 1.8 0.66 9.8 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1797) BCNT PF07572.7 EME84205.1 - 1.4 8.8 6.6 4.1 7.4 1.0 2.7 1 1 1 2 2 2 0 Bucentaur or craniofacial development CFEM PF05730.6 EME84207.1 - 0.37 10.6 11.3 0.58 10.0 7.6 1.6 1 1 0 1 1 1 0 CFEM domain Aldo_ket_red PF00248.16 EME84208.1 - 1.1e-69 234.4 0.0 1.2e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Toxin_39 PF15500.1 EME84208.1 - 0.14 12.3 0.1 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Putative RNase-like toxin MFS_1 PF07690.11 EME84209.1 - 5.3e-14 51.7 32.1 5.3e-14 51.7 22.2 4.2 2 2 0 4 4 4 2 Major Facilitator Superfamily HECT PF00632.20 EME84210.1 - 2.3e-90 302.9 0.0 3.2e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EME84210.1 - 1.1e-32 111.4 15.9 7e-11 41.7 1.2 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EME84210.1 - 4.1e-16 58.5 0.1 9.1e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain Zip PF02535.17 EME84211.1 - 4.7e-41 140.8 10.0 2e-40 138.7 6.9 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2910 PF11139.3 EME84211.1 - 0.011 14.8 6.9 0.018 14.1 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2910) TPT PF03151.11 EME84211.1 - 0.017 14.7 2.2 0.029 14.0 1.2 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF805 PF05656.9 EME84211.1 - 0.3 10.9 3.5 13 5.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF805) FPN1 PF06963.7 EME84213.1 - 2.9e-51 174.2 24.1 1.4e-26 92.9 2.6 2.8 1 1 1 2 2 2 2 Ferroportin1 (FPN1) Amido_AtzD_TrzD PF09663.5 EME84214.1 - 4.4e-86 288.7 0.0 6.6e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Polysacc_deac_1 PF01522.16 EME84215.1 - 2e-13 50.0 0.0 3.9e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase 2OG-FeII_Oxy PF03171.15 EME84217.1 - 0.0084 16.3 0.0 0.029 14.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EME84218.1 - 1.2e-65 215.1 13.6 3.4e-11 42.5 0.3 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EME84218.1 - 9e-13 47.7 0.2 2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME84218.1 - 6.4e-11 41.6 0.1 1.5e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EME84218.1 - 2e-09 36.1 4.8 0.12 10.4 0.0 5.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME84218.1 - 0.0088 14.8 0.0 1.3 7.6 0.0 3.3 2 1 0 3 3 3 1 Nup133 N terminal like APG17 PF04108.7 EME84219.1 - 1.4e-73 248.0 7.6 1.8e-73 247.7 5.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Bacillus_HBL PF05791.6 EME84219.1 - 0.0016 17.8 3.9 0.11 11.8 0.9 2.9 3 0 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) DUF615 PF04751.9 EME84219.1 - 0.011 15.3 1.1 0.011 15.3 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF615) Prominin PF05478.6 EME84219.1 - 0.03 11.8 2.8 0.065 10.7 2.0 1.5 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.7 EME84219.1 - 0.048 13.4 4.8 0.72 9.6 0.0 3.8 2 2 2 4 4 4 0 Laminin Domain II IncA PF04156.9 EME84219.1 - 0.051 13.1 7.2 10 5.6 1.1 3.2 1 1 2 3 3 3 0 IncA protein PAXIP1_C PF15364.1 EME84219.1 - 0.057 13.3 0.4 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Reo_sigmaC PF04582.7 EME84219.1 - 0.13 11.4 8.7 0.99 8.5 0.0 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EME84219.1 - 0.17 12.0 3.3 1.6 8.8 0.4 3.1 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EME84219.1 - 0.19 11.5 5.4 1.8 8.3 1.4 3.1 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 EME84219.1 - 0.21 11.6 7.3 20 5.2 0.2 5.5 4 2 2 6 6 6 0 Proteins of 100 residues with WXG PilJ PF13675.1 EME84219.1 - 0.28 11.5 14.9 5.5 7.3 0.0 4.0 3 1 1 4 4 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Rogdi_lz PF10259.4 EME84219.1 - 0.35 9.9 3.2 0.65 9.0 1.5 1.9 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein 4HB_MCP_1 PF12729.2 EME84219.1 - 1.3 8.3 5.6 0.54 9.5 0.3 2.8 2 2 0 2 2 2 0 Four helix bundle sensory module for signal transduction Barstar PF01337.13 EME84219.1 - 1.4 8.7 4.5 1.4 8.7 0.2 3.0 2 1 0 3 3 2 0 Barstar (barnase inhibitor) DUF3450 PF11932.3 EME84219.1 - 3.3 6.9 13.7 0.22 10.7 0.5 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF3450) CorA PF01544.13 EME84219.1 - 3.5 6.5 11.3 2.2 7.2 1.5 3.3 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein AATF-Che1 PF13339.1 EME84219.1 - 3.6 7.7 11.3 3.9 7.6 2.1 3.8 1 1 4 5 5 5 0 Apoptosis antagonizing transcription factor DivIVA PF05103.8 EME84219.1 - 7.3 6.6 17.0 11 6.0 0.1 4.9 3 2 1 5 5 5 0 DivIVA protein DUF1761 PF08570.5 EME84222.1 - 1.2e-24 86.7 2.9 1.3e-24 86.5 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CD20 PF04103.10 EME84222.1 - 0.12 12.2 1.1 0.17 11.7 0.8 1.2 1 0 0 1 1 1 0 CD20-like family AAA_17 PF13207.1 EME84223.1 - 1.6e-09 38.6 0.5 4.7e-08 33.8 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME84223.1 - 1.2e-05 25.1 0.1 0.00074 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME84223.1 - 5.9e-05 23.3 0.7 0.00084 19.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EME84223.1 - 9.2e-05 21.6 0.2 0.0028 16.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.13 EME84223.1 - 9.8e-05 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EME84223.1 - 9.8e-05 21.3 0.0 0.00034 19.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 EME84223.1 - 0.00014 21.9 0.1 0.00051 20.0 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME84223.1 - 0.00014 21.9 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME84223.1 - 0.00015 21.4 0.0 0.00034 20.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EME84223.1 - 0.0015 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.12 EME84223.1 - 0.0017 17.7 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EME84223.1 - 0.0027 17.7 0.0 0.0027 17.7 0.0 1.9 3 0 0 3 3 1 1 AAA domain AAA PF00004.24 EME84223.1 - 0.0029 17.8 0.0 0.006 16.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EME84223.1 - 0.0038 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 NTPase SRP54 PF00448.17 EME84223.1 - 0.0065 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KTI12 PF08433.5 EME84223.1 - 0.0084 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SKI PF01202.17 EME84223.1 - 0.014 15.2 0.1 1.4 8.7 0.0 2.4 2 1 0 2 2 2 0 Shikimate kinase DUF2075 PF09848.4 EME84223.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EME84223.1 - 0.025 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EME84223.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EME84223.1 - 0.036 13.0 0.0 0.061 12.3 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SE PF00437.15 EME84223.1 - 0.048 12.5 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EME84223.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EME84223.1 - 0.059 13.1 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 EME84223.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RuvB_N PF05496.7 EME84223.1 - 0.09 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus CbiA PF01656.18 EME84223.1 - 0.1 12.0 0.0 0.3 10.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EME84223.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EME84223.1 - 0.1 12.1 0.2 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 EME84224.1 - 1.2e-22 80.5 2.0 1.5e-22 80.2 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84224.1 - 1e-14 54.8 0.0 4.2e-14 52.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84224.1 - 3.8e-10 39.7 0.2 5.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84224.1 - 0.0036 16.7 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2523 PF10734.4 EME84224.1 - 0.05 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) Glyco_transf_22 PF03901.12 EME84225.1 - 2.1e-62 211.5 20.0 1.1e-41 143.2 7.3 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family CHRD PF07452.7 EME84226.1 - 0.033 14.7 0.0 0.04 14.5 0.0 1.2 1 0 0 1 1 1 0 CHRD domain DAO PF01266.19 EME84227.1 - 7.8e-49 166.4 0.0 1.5e-48 165.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME84227.1 - 3.1e-09 36.1 0.0 7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EME84227.1 - 1.8e-05 24.0 1.8 0.0002 20.5 1.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME84227.1 - 3.5e-05 23.7 0.1 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EME84227.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EME84227.1 - 0.0074 16.2 0.2 0.022 14.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME84227.1 - 0.029 14.7 0.1 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EME84227.1 - 0.032 14.2 0.1 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding GIDA PF01134.17 EME84227.1 - 0.064 12.1 0.2 0.38 9.5 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EME84227.1 - 0.067 12.0 0.3 0.16 10.8 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EME84227.1 - 0.092 11.7 0.1 0.21 10.6 0.1 1.7 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EME84227.1 - 0.19 10.1 0.4 0.33 9.3 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein AhpC-TSA PF00578.16 EME84228.1 - 1.8e-26 92.2 0.0 2.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME84228.1 - 5.2e-17 61.7 0.2 6.5e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EME84228.1 - 0.00034 20.5 0.0 0.0015 18.4 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Aa_trans PF01490.13 EME84229.1 - 7.4e-45 153.1 25.0 8.3e-45 152.9 17.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EME84229.1 - 2.3e-05 22.9 26.1 2.3e-05 22.9 18.1 1.7 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EME84229.1 - 3.6e-05 22.5 15.6 3.6e-05 22.5 10.8 1.9 2 0 0 2 2 2 1 Spore germination protein CAAD PF14159.1 EME84229.1 - 0.034 13.7 0.3 0.034 13.7 0.2 3.8 6 1 0 6 6 6 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Trp_Tyr_perm PF03222.8 EME84229.1 - 0.041 12.6 19.5 0.062 12.1 13.1 1.8 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family COX6A PF02046.10 EME84229.1 - 0.046 13.6 0.5 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Tweety PF04906.8 EME84229.1 - 0.34 9.2 5.5 0.045 12.1 0.9 1.7 2 0 0 2 2 2 0 Tweety Pox_A9 PF04835.7 EME84229.1 - 7.8 6.4 10.6 3.2 7.7 0.1 3.3 4 0 0 4 4 4 0 A9 protein conserved region GWT1 PF06423.7 EME84229.1 - 9 6.3 10.4 4.1 7.4 0.1 3.4 2 1 1 3 3 3 0 GWT1 zf-C3HC4_3 PF13920.1 EME84230.1 - 2.8e-06 26.9 0.4 5.6e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME84230.1 - 1.5e-05 24.6 0.8 2.7e-05 23.9 0.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME84230.1 - 0.00026 20.9 0.6 0.00045 20.1 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME84230.1 - 0.001 18.7 0.9 0.0018 17.9 0.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EME84230.1 - 0.0073 15.9 0.6 0.012 15.2 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 EME84230.1 - 0.062 13.0 2.0 0.2 11.3 1.6 1.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 EME84230.1 - 0.064 13.0 0.3 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.2 EME84230.1 - 0.064 13.0 0.4 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.7 EME84230.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-rbx1 PF12678.2 EME84230.1 - 0.11 12.6 0.1 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EME84230.1 - 0.25 10.9 1.7 0.44 10.1 1.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FA_desaturase PF00487.19 EME84231.1 - 1.3e-27 96.8 15.6 1.7e-27 96.5 10.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EME84231.1 - 8.7e-19 66.4 0.0 1.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) AMP-binding PF00501.23 EME84232.1 - 3.1e-69 233.3 0.0 3.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME84232.1 - 1.4e-13 51.5 0.6 4.6e-13 49.9 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH PF00378.15 EME84233.1 - 5e-27 94.5 0.0 5.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF433 PF04255.9 EME84233.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Pkinase PF00069.20 EME84235.1 - 1.4e-53 181.6 0.0 1.9e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84235.1 - 1.1e-17 64.0 0.0 1.7e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME84235.1 - 0.0002 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Med25_VWA PF11265.3 EME84235.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A RGS PF00615.14 EME84236.1 - 3.8e-30 104.3 0.0 8.9e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EME84236.1 - 8.9e-19 67.0 0.0 5.4e-13 48.4 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.1 EME84236.1 - 0.052 13.4 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Replication-relaxation DUF4630 PF15443.1 EME84238.1 - 0.13 12.0 0.5 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) AMP-binding PF00501.23 EME84239.1 - 3.4e-18 65.2 0.0 5.1e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EME84239.1 - 1.2e-06 28.6 0.0 3.1e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 EME84239.1 - 4.1e-06 25.8 0.2 0.00011 21.1 0.1 2.2 2 0 0 2 2 2 1 Condensation domain AMP-binding_C PF13193.1 EME84239.1 - 0.068 14.1 0.0 0.18 12.7 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3405 PF11885.3 EME84240.1 - 2.4e-212 705.5 8.4 3e-212 705.2 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) FAD_binding_3 PF01494.14 EME84241.1 - 2.3e-85 286.7 0.0 3.8e-85 286.0 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EME84241.1 - 3e-48 163.6 0.0 4.8e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EME84241.1 - 7.2e-05 22.7 0.2 0.00049 20.0 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME84241.1 - 0.00014 20.8 0.1 0.00024 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME84241.1 - 0.00017 20.1 0.1 0.00033 19.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EME84241.1 - 0.00047 19.3 0.0 0.0029 16.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EME84241.1 - 0.0029 17.6 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME84241.1 - 0.0052 15.7 0.1 0.0093 14.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EME84241.1 - 0.038 12.8 0.0 0.076 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME84241.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME84241.1 - 0.079 11.7 0.1 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EME84241.1 - 0.081 12.9 0.4 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tcp11 PF05794.8 EME84244.1 - 1.4e-67 228.3 1.6 2e-67 227.8 1.1 1.2 1 0 0 1 1 1 1 T-complex protein 11 PLDc_N PF13396.1 EME84245.1 - 6e-09 35.4 9.4 6e-09 35.4 6.5 1.5 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal PTS_EIIC_2 PF13303.1 EME84245.1 - 0.011 14.6 0.5 0.013 14.3 0.4 1.0 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF4184 PF13803.1 EME84245.1 - 0.016 14.5 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) Orai-1 PF07856.7 EME84245.1 - 0.028 13.9 0.5 0.031 13.8 0.3 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF3671 PF12420.3 EME84245.1 - 0.041 13.8 0.3 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF1475 PF07343.6 EME84245.1 - 0.041 13.2 1.5 0.044 13.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1475) Pox_A14 PF05767.7 EME84245.1 - 0.063 13.2 0.3 0.081 12.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2207 PF09972.4 EME84245.1 - 0.13 10.8 0.5 0.14 10.7 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3951 PF13131.1 EME84245.1 - 0.31 10.8 0.2 0.31 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) EmrE PF13536.1 EME84245.1 - 0.34 11.1 4.0 0.58 10.3 2.8 1.4 1 1 0 1 1 1 0 Multidrug resistance efflux transporter DUF4064 PF13273.1 EME84245.1 - 1.4 9.0 5.6 15 5.7 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PspC PF04024.7 EME84245.1 - 2.6 7.5 6.1 1.2 8.6 0.8 2.1 2 0 0 2 2 2 0 PspC domain Transp_cyt_pur PF02133.10 EME84246.1 - 7.2e-77 258.7 38.5 8.5e-77 258.5 26.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF485 PF04341.7 EME84246.1 - 0.53 10.0 9.0 0.59 9.8 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Sugar_tr PF00083.19 EME84247.1 - 5.2e-104 348.3 17.7 6.1e-104 348.0 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME84247.1 - 1.2e-27 96.5 24.6 1.2e-27 96.5 17.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EME84247.1 - 0.0095 15.7 0.0 0.04 13.7 0.0 2.1 1 0 0 1 1 1 1 MFS_1 like family Phage_holin_2 PF04550.7 EME84247.1 - 0.049 13.7 1.5 0.23 11.5 1.0 2.2 1 0 0 1 1 1 0 Phage holin family 2 zf-RING_5 PF14634.1 EME84249.1 - 8.9e-05 22.1 2.6 0.00033 20.3 1.8 1.9 1 1 1 2 2 2 1 zinc-RING finger domain YlqD PF11068.3 EME84249.1 - 0.048 13.6 4.1 0.054 13.5 2.2 1.4 1 1 0 1 1 1 0 YlqD protein zf-rbx1 PF12678.2 EME84249.1 - 0.44 10.6 2.6 1.5 9.0 1.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 EME84249.1 - 4.2 7.2 6.7 59 3.6 4.6 2.5 1 1 0 1 1 1 0 Ring finger domain adh_short PF00106.20 EME84250.1 - 4.7e-21 75.4 0.1 9.8e-21 74.3 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84250.1 - 3.1e-16 59.8 0.0 4.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84250.1 - 3.6e-05 23.5 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84250.1 - 0.001 18.5 0.0 0.0025 17.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 EME84251.1 - 8e-10 38.0 0.0 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME84251.1 - 0.00018 21.3 5.6 0.00032 20.5 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EME84252.1 - 2.3e-55 186.5 0.0 3.1e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME84252.1 - 4.4e-17 61.8 0.0 5.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME84252.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EME84252.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Sugar_tr PF00083.19 EME84253.1 - 5.9e-124 414.0 28.7 6.7e-124 413.8 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME84253.1 - 6.3e-22 77.7 27.5 6.3e-22 77.7 19.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily KOW PF00467.24 EME84254.1 - 2.1e-05 24.0 2.3 4.9e-05 22.8 1.6 1.6 1 0 0 1 1 1 1 KOW motif Barwin PF00967.12 EME84256.1 - 7.4e-05 22.4 0.4 0.00012 21.7 0.3 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EME84256.1 - 0.00018 21.4 0.1 0.00058 19.8 0.1 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 EME84256.1 - 1.1 8.6 19.4 1.2 8.4 13.4 1.1 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EME84258.1 - 4.8e-18 65.6 0.2 5.2e-13 49.2 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EME84258.1 - 1.4e-06 28.0 0.2 0.0011 18.6 0.0 2.2 1 1 1 2 2 2 2 KR domain Epimerase PF01370.16 EME84258.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME84258.1 - 0.037 14.0 0.5 0.11 12.4 0.4 1.8 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EME84258.1 - 0.21 10.2 0.5 0.87 8.2 0.4 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SKG6 PF08693.5 EME84260.1 - 2.1e-07 30.1 5.4 5.2e-07 28.8 3.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EME84260.1 - 0.00034 20.1 0.1 0.00049 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EME84260.1 - 0.002 17.8 12.0 0.072 12.7 8.3 2.4 1 1 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EME84260.1 - 0.02 13.1 0.0 0.031 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3301 PF11743.3 EME84260.1 - 0.046 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF3377 PF11857.3 EME84260.1 - 0.047 13.3 0.2 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) EphA2_TM PF14575.1 EME84260.1 - 0.05 13.9 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4366 PF14283.1 EME84260.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2500 PF10694.4 EME84260.1 - 0.15 12.1 0.1 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Rifin_STEVOR PF02009.11 EME84260.1 - 0.2 11.2 0.1 0.38 10.3 0.0 1.5 1 1 0 1 1 1 0 Rifin/stevor family DUF294 PF03445.8 EME84261.1 - 0.1 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 Porin_3 PF01459.17 EME84262.1 - 1.3e-47 162.3 4.2 1.7e-47 162.0 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic porin COesterase PF00135.23 EME84263.1 - 3.9e-85 286.5 0.4 5.1e-85 286.1 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME84263.1 - 1.3e-06 28.1 0.0 3.8e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME84263.1 - 0.0015 17.7 1.1 0.0024 17.1 0.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family adh_short PF00106.20 EME84264.1 - 1e-22 80.8 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84264.1 - 9.3e-09 35.3 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84264.1 - 3e-08 33.5 0.0 8.9e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84264.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME84264.1 - 0.063 11.9 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mcp5_PH PF12814.2 EME84265.1 - 1e-42 144.8 0.3 2.8e-42 143.5 0.1 1.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EME84265.1 - 2.3 7.9 42.2 0.06 13.0 15.4 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-C3HC4_2 PF13923.1 EME84266.1 - 5.9e-09 35.8 9.8 1e-08 35.0 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EME84266.1 - 2.9e-08 33.1 2.3 5.8e-08 32.2 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EME84266.1 - 1.5e-07 30.9 6.5 2.5e-07 30.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME84266.1 - 2e-07 30.5 10.6 3.5e-07 29.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME84266.1 - 3e-07 30.1 5.6 5e-07 29.4 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME84266.1 - 2.2e-06 27.2 9.8 4e-06 26.4 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME84266.1 - 0.00019 21.2 8.3 0.00044 20.0 5.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME84266.1 - 0.0011 18.6 5.6 0.0026 17.4 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EME84266.1 - 0.0041 16.6 4.5 0.0073 15.7 3.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L37e PF01907.14 EME84266.1 - 0.13 12.0 7.8 0.059 13.1 2.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e Voltage_CLC PF00654.15 EME84269.1 - 7.6e-95 317.9 19.5 1.3e-94 317.1 13.5 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel TAT_signal PF10518.4 EME84269.1 - 0.033 14.1 1.0 0.033 14.1 0.7 3.0 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence UCH PF00443.24 EME84270.1 - 2.3e-74 249.9 0.0 1e-73 247.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME84270.1 - 2.8e-14 53.2 0.0 3.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EME84270.1 - 1.5e-07 31.7 0.0 1.2e-06 28.8 0.0 2.6 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.1 EME84270.1 - 0.0029 17.0 0.2 0.0056 16.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal DUF3685 PF12452.3 EME84270.1 - 0.26 10.4 0.0 0.54 9.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) PHD PF00628.24 EME84270.1 - 0.37 10.5 0.6 0.95 9.1 0.4 1.7 1 0 0 1 1 1 0 PHD-finger Tweety PF04906.8 EME84271.1 - 0.0038 15.6 1.0 0.0038 15.6 0.7 1.6 1 1 1 2 2 2 2 Tweety Consortin_C PF15281.1 EME84271.1 - 0.037 13.5 0.6 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Consortin C-terminus DUF3329 PF11808.3 EME84273.1 - 0.32 11.1 1.3 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Methyltransf_23 PF13489.1 EME84274.1 - 6.3e-16 58.5 0.0 9.4e-16 57.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME84274.1 - 8.8e-15 54.6 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME84274.1 - 1.8e-12 47.6 0.0 3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME84274.1 - 2.1e-11 44.3 0.0 3.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME84274.1 - 4.9e-10 39.7 0.0 1.8e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EME84274.1 - 1.6e-06 27.4 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EME84274.1 - 3.2e-06 27.4 0.0 7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME84274.1 - 2.7e-05 24.2 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EME84274.1 - 0.00025 21.0 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME84274.1 - 0.00026 20.3 0.0 0.00052 19.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 EME84274.1 - 0.0066 15.5 0.0 0.069 12.2 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 EME84274.1 - 0.01 14.7 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 EME84274.1 - 0.016 14.3 0.0 0.042 12.9 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EME84274.1 - 0.027 13.5 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Glyco_transf_90 PF05686.7 EME84275.1 - 4.6e-30 104.5 1.2 6.4e-30 104.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Abhydrolase_1 PF00561.15 EME84276.1 - 8.3e-20 71.3 0.0 8.1e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME84276.1 - 5.1e-12 46.1 0.2 1.4e-11 44.7 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME84276.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase ILVD_EDD PF00920.16 EME84278.1 - 3.8e-197 655.8 0.1 4.3e-197 655.6 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family CDV3 PF15359.1 EME84279.1 - 0.12 12.4 3.9 0.39 10.8 2.7 1.8 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 TFIIF_alpha PF05793.7 EME84280.1 - 0.51 8.6 12.1 0.63 8.3 8.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EBV-NA3 PF05009.7 EME84280.1 - 4.3 6.5 6.2 6.7 5.8 4.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.7 EME84280.1 - 8.3 5.5 9.9 9.8 5.3 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein zf-CHY PF05495.7 EME84281.1 - 8e-13 48.3 22.4 8e-13 48.3 15.5 3.5 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EME84281.1 - 2.5e-09 36.7 5.6 2.5e-09 36.7 3.8 4.3 1 1 3 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME84281.1 - 1.5e-08 34.1 3.7 1.5e-08 34.1 2.6 4.8 1 1 3 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME84281.1 - 2.7e-07 30.4 4.4 2.7e-07 30.4 3.1 4.7 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_6 PF14599.1 EME84281.1 - 0.00011 21.8 0.3 0.00011 21.8 0.2 6.2 3 1 2 6 6 6 1 Zinc-ribbon zf-RING_5 PF14634.1 EME84281.1 - 0.0046 16.6 15.0 0.0046 16.6 10.4 6.2 2 2 1 3 3 3 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EME84281.1 - 0.08 12.6 0.2 0.08 12.6 0.1 5.7 3 3 3 6 6 6 0 Prokaryotic RING finger family 1 RasGEF PF00617.14 EME84282.1 - 3.3e-51 173.7 0.2 5.4e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EME84282.1 - 3.8e-15 55.8 0.1 1.7e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EME84282.1 - 0.00017 21.0 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME84282.1 - 0.0023 17.2 0.1 0.0071 15.7 0.0 1.9 1 1 0 1 1 1 1 SH3 domain Ima1_N PF09779.4 EME84283.1 - 4.2e-34 117.8 7.2 9.7e-34 116.6 5.0 1.7 1 0 0 1 1 1 1 Ima1 N-terminal domain MIP PF00230.15 EME84284.1 - 2.5e-18 66.4 3.4 4.1e-18 65.6 2.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein YCII PF03795.9 EME84285.1 - 3.6e-09 36.6 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain MFS_1 PF07690.11 EME84286.1 - 3.7e-26 91.6 36.9 2.9e-14 52.5 6.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EME84286.1 - 2.4e-11 42.9 2.6 2.4e-11 42.9 1.8 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EME84286.1 - 0.0026 16.0 5.0 0.018 13.2 3.1 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.3 EME84286.1 - 0.28 11.0 5.1 0.4 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) DUF3328 PF11807.3 EME84287.1 - 2.7e-15 56.6 0.0 3.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ferric_reduct PF01794.14 EME84289.1 - 4.3e-18 65.6 11.0 1.5e-17 63.8 7.6 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME84289.1 - 3.2e-05 23.7 0.0 0.00031 20.5 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME84289.1 - 0.013 15.4 4.7 0.29 11.0 0.3 3.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EME84289.1 - 0.018 15.6 0.0 0.068 13.7 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Glyco_hydro_92 PF07971.7 EME84292.1 - 4.8e-167 556.6 0.4 6.2e-167 556.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1279 PF06916.8 EME84294.1 - 3.3e-22 78.5 0.0 5.9e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) PNGaseA PF12222.3 EME84297.1 - 4e-72 243.4 0.4 4.9e-72 243.1 0.3 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1244 PF06844.6 EME84298.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) JmjC PF02373.17 EME84302.1 - 3.5e-10 40.1 2.0 1.7e-09 37.9 0.4 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EME84302.1 - 2.6e-06 27.5 6.7 2.6e-06 27.5 4.7 2.6 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EME84302.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 EME84303.1 - 1.7e-31 109.4 24.5 2.1e-31 109.1 17.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Zn_clus PF00172.13 EME84306.1 - 6.8e-09 35.5 15.2 6.8e-09 35.5 10.5 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF-1_p150 PF11600.3 EME84306.1 - 0.0018 17.7 1.0 0.0023 17.3 0.7 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4446 PF14584.1 EME84306.1 - 0.039 13.7 0.2 0.08 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CENP-F_leu_zip PF10473.4 EME84306.1 - 0.043 13.6 0.2 0.072 12.9 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CRAL_TRIO_2 PF13716.1 EME84307.1 - 2.3e-30 105.4 0.0 3.8e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EME84307.1 - 5.9e-18 64.9 0.0 1.2e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EME84307.1 - 0.00015 21.3 0.1 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain PAS_9 PF13426.1 EME84308.1 - 2.9e-17 62.9 0.0 2e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EME84308.1 - 1.3e-06 28.1 0.0 4.9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 PAS fold Asn_synthase PF00733.16 EME84310.1 - 1.7e-68 230.8 0.0 3e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EME84310.1 - 3.8e-37 126.7 0.0 7.1e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EME84310.1 - 2.1e-28 98.9 0.0 5e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EME84310.1 - 4.7e-06 25.9 0.0 8.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EME84310.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EME84310.1 - 0.026 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Myb_DNA-bind_6 PF13921.1 EME84312.1 - 2.1e-05 24.5 0.1 7e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME84312.1 - 0.0028 17.6 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DMAP1 PF05499.7 EME84312.1 - 0.0087 15.6 0.6 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_5 PF13873.1 EME84312.1 - 0.059 13.2 0.2 2.3 8.1 0.0 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3984 PF13136.1 EME84313.1 - 1.3e-30 106.8 29.8 1.8e-28 99.7 18.5 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3984) DUF3246 PF11596.3 EME84313.1 - 0.04 13.2 4.1 0.028 13.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Potassium_chann PF11404.3 EME84313.1 - 0.12 12.1 1.2 0.27 11.0 0.8 1.6 1 0 0 1 1 1 0 Potassium voltage-gated channel Tyrosinase PF00264.15 EME84314.1 - 7.2e-34 117.8 2.0 9.6e-34 117.4 1.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PPR_2 PF13041.1 EME84315.1 - 4.9e-20 71.2 0.0 2.3e-07 30.7 0.0 4.8 3 2 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 EME84315.1 - 2.7e-17 61.5 0.1 0.00073 19.6 0.0 5.3 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 EME84315.1 - 5.4e-12 44.8 1.2 0.043 13.7 0.0 5.0 4 1 0 4 4 4 3 PPR repeat PPR_1 PF12854.2 EME84315.1 - 1.2e-05 24.6 0.1 0.087 12.3 0.1 3.7 3 1 0 3 3 3 2 PPR repeat MRP-S27 PF10037.4 EME84315.1 - 0.0034 16.3 0.7 0.095 11.6 0.0 2.1 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S27 Rubrerythrin PF02915.12 EME84315.1 - 0.12 12.6 1.6 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Rubrerythrin MRP-S25 PF13741.1 EME84316.1 - 2.2e-50 171.2 12.9 1.6e-25 89.9 0.3 3.0 1 1 2 3 3 3 3 Mitochondrial ribosomal protein S25 Fasciclin PF02469.17 EME84317.1 - 2.5e-38 130.9 0.1 2.8e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain MarR PF01047.17 EME84317.1 - 0.097 12.3 0.1 5.6 6.7 0.0 3.2 3 0 0 3 3 3 0 MarR family COX7C PF02935.11 EME84319.1 - 4.4e-16 58.4 2.9 5.1e-16 58.2 2.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldo_ket_red PF00248.16 EME84320.1 - 1.4e-56 191.3 0.0 1.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Semialdhyde_dh PF01118.19 EME84320.1 - 0.055 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EME84321.1 - 4.1e-47 160.1 0.1 7.9e-47 159.2 0.1 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EME84321.1 - 2.1e-29 102.2 0.2 4e-29 101.2 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EME84321.1 - 3.5e-16 59.3 0.0 6.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EME84321.1 - 1.2e-07 31.8 0.1 3e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EME84321.1 - 2.2e-05 25.3 0.0 7.5e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EME84321.1 - 3.9e-05 23.6 2.6 0.00018 21.4 0.8 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME84321.1 - 0.0009 18.9 0.4 0.0032 17.1 0.3 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EME84321.1 - 0.0023 16.7 0.0 0.019 13.6 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME84321.1 - 0.0039 17.2 0.9 0.53 10.2 0.1 3.3 4 0 0 4 4 4 1 NADH(P)-binding NmrA PF05368.8 EME84321.1 - 0.044 13.0 0.1 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EME84321.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NIF PF03031.13 EME84325.1 - 1.2e-49 167.9 0.0 1.4e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 EME84326.1 - 2.3e-55 187.5 7.8 4.3e-31 107.9 0.1 3.2 2 1 1 3 3 3 3 Initiation factor 2 subunit family Dickkopf_N PF04706.7 EME84327.1 - 0.021 14.9 8.1 0.059 13.5 5.6 1.8 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DAO PF01266.19 EME84329.1 - 1.6e-40 139.1 0.1 1.9e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME84329.1 - 0.0015 18.3 0.0 0.0091 15.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME84329.1 - 0.0034 17.4 0.0 2.2 8.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME84329.1 - 0.083 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME84329.1 - 0.092 12.6 0.0 0.71 9.7 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4581 PF15167.1 EME84329.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) SBP_bac_6 PF13343.1 EME84330.1 - 3.3e-17 62.6 1.8 2.2e-16 59.9 1.2 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.1 EME84330.1 - 2.8e-09 37.1 9.1 3.7e-07 30.1 5.4 2.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EME84330.1 - 0.0001 22.0 0.3 0.0001 22.0 0.2 2.2 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EME84330.1 - 0.0031 17.3 6.9 0.034 13.8 4.7 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Chorion_2 PF03964.10 EME84330.1 - 1.4 9.5 6.1 0.73 10.4 2.1 2.0 2 0 0 2 2 2 0 Chorion family 2 DUF1329 PF07044.6 EME84331.1 - 0.086 11.7 0.6 0.12 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) FAD_binding_3 PF01494.14 EME84332.1 - 1.2e-14 54.1 0.0 3.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME84332.1 - 5.2e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME84332.1 - 0.0023 17.8 0.0 0.0087 15.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME84332.1 - 0.0039 16.3 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 EME84332.1 - 0.0044 17.0 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EME84332.1 - 0.0059 16.3 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EME84332.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME84332.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EME84332.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EME84332.1 - 0.17 10.3 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EME84332.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ABC2_membrane PF01061.19 EME84333.1 - 7.1e-95 316.1 50.8 4.2e-49 166.5 14.0 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EME84333.1 - 2e-42 142.9 2.1 1.4e-34 117.8 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EME84333.1 - 1.6e-37 128.8 0.0 4.9e-17 62.5 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 EME84333.1 - 4.8e-20 71.4 0.0 1.6e-19 69.7 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EME84333.1 - 2.5e-07 30.2 0.0 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME84333.1 - 3.3e-06 27.2 0.3 0.0042 17.0 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EME84333.1 - 3.4e-06 26.3 0.0 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EME84333.1 - 5.4e-05 23.0 0.2 0.022 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EME84333.1 - 9.5e-05 21.9 0.4 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EME84333.1 - 9.6e-05 21.8 1.1 0.022 14.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EME84333.1 - 0.00089 19.5 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EME84333.1 - 0.0014 17.8 0.0 0.45 9.6 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EME84333.1 - 0.0016 18.5 0.1 1.7 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EME84333.1 - 0.0038 18.0 0.0 0.43 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME84333.1 - 0.011 15.7 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EME84333.1 - 0.011 15.4 1.1 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain TPR_9 PF13371.1 EME84333.1 - 0.019 14.8 0.2 0.064 13.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_helicase PF00910.17 EME84333.1 - 0.021 15.0 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EME84333.1 - 0.026 14.1 0.7 2.4 7.7 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EME84333.1 - 0.049 13.5 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EME84333.1 - 0.061 13.5 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EME84333.1 - 0.078 12.5 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EME84333.1 - 0.25 11.0 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 EME84333.1 - 0.27 11.2 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 EME84333.1 - 0.36 9.6 0.1 4.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein MFS_1 PF07690.11 EME84334.1 - 4.1e-27 94.8 30.1 4.1e-27 94.8 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Arylsulfotran_2 PF14269.1 EME84335.1 - 3.2e-37 128.3 0.3 4e-37 127.9 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME84335.1 - 1.1e-09 37.4 1.2 4.4e-08 32.0 0.8 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) HsbA PF12296.3 EME84336.1 - 5e-17 61.9 2.3 7.9e-17 61.2 1.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF2277 PF10041.4 EME84336.1 - 0.0071 16.2 4.6 0.2 11.6 0.1 3.4 2 1 2 4 4 4 2 Uncharacterized conserved protein (DUF2277) DUF4142 PF13628.1 EME84336.1 - 0.075 13.0 2.3 3.6 7.6 0.1 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4142) CoA_transf_3 PF02515.12 EME84337.1 - 2.6e-27 95.3 0.1 4.4e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III 3HCDH_N PF02737.13 EME84338.1 - 3.8e-42 143.9 0.0 5.1e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EME84338.1 - 1.9e-10 40.9 0.0 3.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 EME84338.1 - 0.0057 15.8 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EME84338.1 - 0.0077 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EME84338.1 - 0.078 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME84338.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EME84338.1 - 0.14 12.6 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldl_recept_b PF00058.12 EME84340.1 - 5.2e-06 26.6 4.1 0.0021 18.3 0.0 4.8 6 0 0 6 6 6 1 Low-density lipoprotein receptor repeat class B SGL PF08450.7 EME84340.1 - 0.00013 21.4 0.1 0.016 14.6 0.0 2.3 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EME84340.1 - 0.033 14.1 0.0 2.1 8.4 0.0 3.3 3 0 0 3 3 3 0 NHL repeat adh_short PF00106.20 EME84341.1 - 9.4e-26 90.7 0.3 1.6e-25 89.9 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84341.1 - 2.3e-25 89.7 0.0 2.9e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84341.1 - 1.5e-11 44.3 0.2 2.6e-11 43.4 0.0 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EME84341.1 - 0.032 13.1 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein APOBEC_C PF05240.9 EME84341.1 - 0.12 11.7 0.0 0.34 10.3 0.0 1.8 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Med5 PF08689.5 EME84342.1 - 1.4e-120 403.7 0.6 1.8e-120 403.3 0.4 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 Mito_carr PF00153.22 EME84343.1 - 2.5e-42 142.4 2.3 2.3e-14 52.8 0.0 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein MRP-S32 PF10210.4 EME84344.1 - 0.052 13.8 0.1 0.061 13.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Pkinase PF00069.20 EME84346.1 - 6.1e-69 232.0 0.0 1.1e-68 231.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84346.1 - 9.6e-51 172.3 0.0 1.6e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME84346.1 - 7.3e-05 21.8 0.0 0.00017 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EME84346.1 - 0.2 10.4 1.5 1 8.1 0.1 2.7 3 0 0 3 3 3 0 Seadornavirus VP7 Serglycin PF04360.7 EME84347.1 - 0.42 10.3 2.7 0.95 9.1 1.8 1.6 1 1 0 1 1 1 0 Serglycin SGL PF08450.7 EME84348.1 - 0.00023 20.6 0.0 0.014 14.7 0.0 3.1 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EME84348.1 - 0.013 15.3 0.5 16 5.9 0.0 4.5 4 0 0 4 4 4 0 Two component regulator propeller PQQ PF01011.16 EME84348.1 - 0.099 12.2 0.1 26 4.5 0.0 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat CMD PF02627.15 EME84349.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Nucleo_P87 PF07267.6 EME84350.1 - 0.89 8.1 3.1 1 7.9 2.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1180 PF06679.7 EME84351.1 - 0.31 10.9 2.1 0.33 10.8 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HHH PF00633.18 EME84352.1 - 0.00019 20.9 0.1 0.0004 19.9 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif CWC25 PF12542.3 EME84352.1 - 0.021 15.2 1.7 0.037 14.4 1.2 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor CPSF100_C PF13299.1 EME84352.1 - 0.75 9.9 4.6 1.2 9.3 3.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MmgE_PrpD PF03972.9 EME84353.1 - 6.5e-75 251.9 1.8 7.8e-75 251.7 1.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RLI PF04068.10 EME84354.1 - 0.34 10.5 3.2 0.65 9.6 0.7 2.5 1 1 1 2 2 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI UDPG_MGDP_dh PF00984.14 EME84355.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF2353 PF09789.4 EME84356.1 - 0.057 12.6 0.1 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) IFT20 PF14931.1 EME84356.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF607 PF04678.8 EME84358.1 - 5.1e-41 140.5 2.9 8.2e-41 139.8 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF607 Granulin PF00396.13 EME84359.1 - 0.76 9.9 14.8 1.6 8.8 3.1 2.4 1 1 1 2 2 2 0 Granulin Asp PF00026.18 EME84361.1 - 1.1e-51 176.0 1.4 2.1e-51 175.1 1.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME84361.1 - 3e-11 43.5 0.2 3e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME84361.1 - 4e-06 27.2 2.7 0.007 16.8 0.0 4.0 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EME84361.1 - 0.0033 16.9 0.0 0.0091 15.5 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EME84361.1 - 0.057 13.2 0.0 5.7 6.8 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease HSCB_C PF07743.8 EME84362.1 - 0.2 12.1 1.9 0.29 11.6 0.6 1.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Arch_ATPase PF01637.13 EME84363.1 - 2.9e-15 56.6 0.4 2.1e-14 53.7 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EME84363.1 - 8e-06 25.9 2.7 1.7e-05 24.8 0.6 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME84363.1 - 3.6e-05 23.9 0.0 0.0067 16.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EME84363.1 - 0.002 18.0 0.0 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EME84363.1 - 0.028 14.2 1.3 0.13 12.0 0.9 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Coa1 PF08695.5 EME84364.1 - 3.6e-41 139.3 0.1 5.5e-41 138.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Methyltransf_16 PF10294.4 EME84367.1 - 7.2e-46 155.7 0.0 8.8e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EME84367.1 - 0.0045 17.5 0.0 0.006 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME84367.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain He_PIG PF05345.7 EME84368.1 - 5.3e-22 77.5 16.1 1.7e-06 27.9 2.7 5.5 5 1 0 5 5 5 4 Putative Ig domain Sarcoglycan_2 PF05510.8 EME84368.1 - 0.013 13.7 0.1 0.092 11.0 0.0 2.2 2 1 0 2 2 2 0 Sarcoglycan alpha/epsilon Big_3_4 PF13754.1 EME84368.1 - 7.5 6.9 21.1 0.65 10.3 1.2 5.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF4149 PF13664.1 EME84369.1 - 0.0019 18.2 0.3 0.11 12.5 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1109 PF06532.6 EME84369.1 - 0.019 14.3 0.2 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) Tad PF13400.1 EME84369.1 - 6.5 6.8 7.9 1.4 8.9 1.8 2.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Ank_2 PF12796.2 EME84370.1 - 2.8e-27 94.9 0.0 2.6e-10 40.5 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME84370.1 - 5e-24 84.2 0.1 9.5e-10 38.7 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME84370.1 - 4.4e-18 63.5 1.7 0.00025 20.9 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.25 EME84370.1 - 6.4e-18 63.5 0.3 5e-05 22.8 0.0 7.2 6 1 1 7 7 7 3 Ankyrin repeat SPX PF03105.14 EME84370.1 - 1.8e-17 64.0 3.7 4.4e-17 62.7 2.6 1.5 1 1 0 1 1 1 1 SPX domain Ank_5 PF13857.1 EME84370.1 - 3.3e-13 49.4 1.1 5.8e-05 23.1 0.0 5.7 3 2 4 7 7 7 4 Ankyrin repeats (many copies) GDPD PF03009.12 EME84370.1 - 7.4e-11 42.0 0.0 1.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family NAD_binding_10 PF13460.1 EME84372.1 - 2.3e-10 40.7 0.0 2.7e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME84372.1 - 0.00021 20.7 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME84372.1 - 0.0026 16.5 0.0 0.0046 15.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME84372.1 - 0.0043 16.0 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EME84372.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EME84372.1 - 0.15 10.9 0.0 0.52 9.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1769 PF08588.5 EME84373.1 - 3.1e-23 81.4 0.1 5.7e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DIOX_N PF14226.1 EME84374.1 - 9.2e-19 68.0 0.0 2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME84374.1 - 2.3e-11 43.8 0.0 4.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3650 PF12368.3 EME84374.1 - 0.13 11.7 0.1 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) GST_C PF00043.20 EME84376.1 - 4.9e-16 58.4 1.3 1.1e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME84376.1 - 5.8e-07 29.6 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME84376.1 - 3.5e-06 26.8 0.0 6.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME84376.1 - 4.9e-06 26.3 0.1 8.6e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME84376.1 - 1.6e-05 25.3 0.0 2.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME84376.1 - 5e-05 23.3 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CutC PF03932.9 EME84377.1 - 3e-57 193.1 0.0 3.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 CutC family Thiolase_N PF00108.18 EME84378.1 - 2.7e-76 256.0 1.8 4.3e-76 255.3 1.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME84378.1 - 7.4e-45 151.3 0.2 1.5e-44 150.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME84378.1 - 0.0082 15.6 4.2 0.18 11.2 0.7 3.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SinI PF08671.5 EME84378.1 - 0.089 12.2 0.2 16 5.0 0.0 2.5 2 0 0 2 2 2 0 Anti-repressor SinI ACP_syn_III PF08545.5 EME84378.1 - 0.12 12.0 0.8 16 5.2 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CorA PF01544.13 EME84380.1 - 2.8e-05 23.3 2.5 5.4e-05 22.3 1.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Amidinotransf PF02274.12 EME84380.1 - 0.13 11.3 0.3 0.2 10.7 0.2 1.1 1 0 0 1 1 1 0 Amidinotransferase Acyltransferase PF01553.16 EME84381.1 - 4.1e-10 39.1 0.0 2.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase DUF1989 PF09347.5 EME84382.1 - 6.2e-32 110.3 0.0 9.8e-32 109.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Glyco_hydro_53 PF07745.8 EME84383.1 - 1.1e-108 362.9 0.3 1.2e-108 362.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Acetyltransf_8 PF13523.1 EME84385.1 - 1.8e-46 157.7 0.0 2.7e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME84385.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD-oxidase_C PF02913.14 EME84386.1 - 4.7e-53 180.0 0.1 8.3e-53 179.2 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EME84386.1 - 1.1e-37 128.6 0.0 2.3e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Tautomerase PF01361.16 EME84386.1 - 0.039 13.5 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 Tautomerase enzyme DUF4477 PF14780.1 EME84387.1 - 0.012 15.0 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Suppressor_APC PF11414.3 EME84387.1 - 0.55 10.0 3.7 1.1 9.0 0.6 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Gly_transf_sug PF04488.10 EME84388.1 - 9.3e-13 48.4 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CNH PF00780.17 EME84389.1 - 1.8e-70 237.5 0.0 4e-70 236.3 0.0 1.6 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EME84389.1 - 9.5e-44 148.6 0.0 2.5e-43 147.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EME84389.1 - 1.5e-38 132.4 0.3 3.1e-38 131.4 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EME84389.1 - 5.8e-12 45.1 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3087 PF11286.3 EME84389.1 - 0.095 11.9 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) ATP-synt_C PF00137.16 EME84390.1 - 3.1e-27 94.2 30.1 6e-16 58.1 5.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C HeLo PF14479.1 EME84391.1 - 2.9e-05 23.9 3.0 0.17 11.5 0.1 3.2 3 1 1 4 4 4 2 Prion-inhibition and propagation GTP_EFTU PF00009.22 EME84392.1 - 7.1e-38 129.9 0.0 1.1e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EME84392.1 - 2.5e-24 84.9 0.1 9e-24 83.1 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EME84392.1 - 4.5e-17 61.7 0.0 1.6e-15 56.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME84392.1 - 1.1e-06 28.6 0.0 3.8e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EME84392.1 - 0.00024 20.6 0.0 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV XPC-binding PF09280.6 EME84392.1 - 0.032 13.6 0.1 2.1 7.8 0.0 2.6 2 0 0 2 2 2 0 XPC-binding domain DUF2095 PF09868.4 EME84392.1 - 0.11 12.3 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Vps5 PF09325.5 EME84393.1 - 5.4e-17 61.8 5.5 9e-17 61.1 3.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EME84393.1 - 1.7e-10 40.6 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 PX domain CENP-H PF05837.7 EME84393.1 - 4.4 7.5 8.9 27 4.9 0.0 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) ADH_N PF08240.7 EME84394.1 - 3.2e-31 107.3 1.4 7.3e-31 106.1 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME84394.1 - 5.6e-29 100.3 0.1 8.6e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME84394.1 - 2.5e-06 28.4 0.0 5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EME84394.1 - 2.4e-05 24.5 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME84394.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EME84394.1 - 0.03 14.7 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EME84394.1 - 0.039 14.0 0.1 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EME84394.1 - 0.055 13.3 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 EME84394.1 - 0.064 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EME84394.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_3 PF07859.8 EME84397.1 - 2.2e-35 122.1 0.4 2.9e-35 121.7 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME84397.1 - 0.00033 20.4 0.0 0.00076 19.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EME84397.1 - 0.0045 15.6 0.0 0.0064 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) ATP_bind_3 PF01171.15 EME84398.1 - 2.4e-19 69.5 0.0 3.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 EME84398.1 - 0.0014 18.0 1.1 0.0014 18.0 0.8 3.1 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.11 EME84398.1 - 0.0048 15.4 0.0 0.0073 14.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase zf-C3HC4_3 PF13920.1 EME84398.1 - 0.11 12.1 0.3 0.11 12.1 0.2 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.15 EME84398.1 - 9.2 6.0 8.8 3.8 7.3 0.1 2.8 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) GCFC PF07842.7 EME84400.1 - 9.7e-79 264.5 8.8 1.7e-78 263.7 6.1 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EME84400.1 - 3.9e-15 55.3 4.1 7.1e-15 54.5 2.8 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EME84400.1 - 2.5e-08 33.6 1.4 9.7e-08 31.7 1.0 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site Pol_alpha_B_N PF08418.5 EME84400.1 - 0.26 10.7 2.5 0.45 10.0 1.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Transket_pyr PF02779.19 EME84401.1 - 1.1e-62 210.6 0.0 1.8e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EME84401.1 - 2.3e-54 184.1 0.0 3.2e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component EST1_DNA_bind PF10373.4 EME84402.1 - 3.2e-09 36.4 0.0 8.8e-09 34.9 0.0 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Collagen PF01391.13 EME84403.1 - 0.99 8.9 7.5 1 8.9 3.8 1.9 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) RAI16-like PF10257.4 EME84404.1 - 6.4e-65 219.3 1.5 1.1e-64 218.6 1.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein HEAT PF02985.17 EME84406.1 - 0.00044 20.0 0.5 0.051 13.6 0.0 4.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EME84406.1 - 0.0049 17.1 1.3 0.23 11.7 0.0 3.9 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EME84406.1 - 0.0093 16.4 1.7 0.069 13.6 0.1 3.5 3 0 0 3 3 3 1 HEAT-like repeat Myosin_head PF00063.16 EME84407.1 - 3.2e-250 831.9 0.0 3.2e-250 831.9 0.0 2.8 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EME84407.1 - 3.6e-32 111.0 277.6 2.4e-24 85.1 40.4 7.1 3 2 4 7 7 7 7 Myosin tail AAA_19 PF13245.1 EME84407.1 - 0.05 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain YtfJ_HI0045 PF09695.5 EME84408.1 - 0.022 14.0 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) zf-C3H1 PF10650.4 EME84409.1 - 5.1e-08 32.2 0.5 8.3e-08 31.5 0.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain 2OG-FeII_Oxy_2 PF13532.1 EME84410.1 - 3.5e-14 53.0 0.0 6.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CENP-B_dimeris PF09026.5 EME84412.1 - 0.02 15.0 17.8 0.7 10.1 9.4 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Spt5_N PF11942.3 EME84412.1 - 0.21 12.2 25.6 0.92 10.1 7.6 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal L31 PF09784.4 EME84413.1 - 1.4e-44 150.4 1.1 1.5e-44 150.2 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.8 EME84414.1 - 1.2e-40 138.4 0.0 1.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EME84414.1 - 4.9e-06 26.3 0.0 0.00056 19.6 0.0 2.2 2 0 0 2 2 2 2 Sybindin-like family MFS_1 PF07690.11 EME84415.1 - 7.5e-28 97.2 49.2 4.2e-15 55.3 9.2 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4121 PF13497.1 EME84415.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) CoA_trans PF01144.18 EME84417.1 - 1.1e-103 345.0 2.4 3.6e-61 206.1 0.3 2.1 2 0 0 2 2 2 2 Coenzyme A transferase BOFC_N PF08977.5 EME84417.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal AcetylCoA_hyd_C PF13336.1 EME84417.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain RTA1 PF04479.8 EME84418.1 - 2.1e-12 47.0 2.3 2.5e-12 46.7 1.6 1.0 1 0 0 1 1 1 1 RTA1 like protein MerR PF00376.18 EME84419.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HR1 PF02185.11 EME84419.1 - 0.51 10.1 8.5 2 8.2 1.4 3.4 2 1 1 3 3 3 0 Hr1 repeat DUF948 PF06103.6 EME84419.1 - 0.57 10.0 3.6 14 5.6 0.0 4.0 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EME84419.1 - 1.5 8.5 7.2 6.6 6.4 1.3 2.9 3 0 0 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EME84419.1 - 5.3 6.8 10.8 0.31 10.8 0.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Na_Ca_ex PF01699.19 EME84420.1 - 1.8e-45 153.9 37.8 8.7e-24 83.7 8.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein TMEM173 PF15009.1 EME84420.1 - 2.4 6.9 5.5 0.42 9.3 0.6 1.9 2 0 0 2 2 2 0 Transmembrane protein 173 Zn_clus PF00172.13 EME84421.1 - 4.4e-09 36.0 8.4 4.4e-09 36.0 5.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME84421.1 - 7.1e-07 28.1 0.1 1.3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ApoLp-III PF07464.6 EME84421.1 - 0.0077 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) AMP-binding PF00501.23 EME84423.1 - 4.5e-79 265.7 0.0 5.6e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME84423.1 - 4.1e-13 50.0 0.0 8.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHF5 PF03660.9 EME84424.1 - 1.4e-50 169.8 9.8 1.6e-50 169.6 6.8 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EME84424.1 - 1 9.2 15.4 0.2 11.5 5.4 2.7 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EME84424.1 - 1.7 8.4 15.8 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Opy2 PF09463.5 EME84424.1 - 5.1 7.2 14.3 0.13 12.4 3.1 2.9 2 1 0 2 2 2 0 Opy2 protein Amidohydro_1 PF01979.15 EME84425.1 - 3.5e-15 56.4 1.4 1.1e-06 28.5 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EME84425.1 - 1.2e-09 38.6 7.3 4.4e-06 26.9 0.7 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EME84425.1 - 4.8e-09 35.9 0.1 5.6e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EME84425.1 - 1.2e-08 34.6 2.5 0.013 14.7 1.1 3.1 2 1 0 2 2 2 2 Amidohydrolase family Flavodoxin_1 PF00258.20 EME84426.1 - 6.5e-29 100.7 0.0 1.2e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EME84426.1 - 4.2e-24 85.2 0.0 6.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EME84426.1 - 3.9e-16 59.5 0.0 1.5e-15 57.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EME84426.1 - 0.021 14.2 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Flavodoxin_5 PF12724.2 EME84426.1 - 0.035 14.1 0.0 0.23 11.4 0.0 2.3 2 1 1 3 3 3 0 Flavodoxin domain RRM_1 PF00076.17 EME84428.1 - 1.2e-28 98.5 0.0 8.5e-15 54.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84428.1 - 1e-22 79.8 0.0 3.6e-12 46.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME84428.1 - 1.7e-09 37.3 0.0 7.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EME84428.1 - 0.097 12.3 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain ETF PF01012.16 EME84429.1 - 5.9e-37 126.9 0.6 9e-37 126.3 0.2 1.4 2 0 0 2 2 2 1 Electron transfer flavoprotein domain zf-RING_2 PF13639.1 EME84430.1 - 2e-10 40.3 4.0 2e-10 40.3 2.8 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME84430.1 - 1.2e-08 34.4 4.4 1.6e-08 34.0 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME84430.1 - 1.3e-06 28.2 4.3 1.3e-06 28.2 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME84430.1 - 4.8e-06 26.5 1.7 4.8e-06 26.5 1.2 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME84430.1 - 0.00042 20.0 0.0 0.0046 16.7 0.4 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EME84430.1 - 0.0025 17.4 2.7 0.0025 17.4 1.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME84430.1 - 0.33 10.7 2.4 0.43 10.3 0.2 2.4 2 1 1 3 3 3 0 RING-type zinc-finger CDC45 PF02724.9 EME84430.1 - 0.46 8.4 8.4 0.71 7.8 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EME84430.1 - 1.9 6.8 12.0 3.2 6.1 8.3 1.3 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 EME84430.1 - 3.6 5.3 9.2 5.8 4.6 6.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 EME84430.1 - 4.7 6.5 11.3 8.8 5.6 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RINGv PF12906.2 EME84430.1 - 7.3 6.7 7.4 3.6 7.7 2.4 2.4 2 0 0 2 2 2 0 RING-variant domain Peptidase_M48 PF01435.13 EME84431.1 - 9.8e-35 120.1 0.0 1.5e-34 119.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M48 DUF946 PF06101.6 EME84431.1 - 0.14 10.0 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) Amidase PF01425.16 EME84432.1 - 3.5e-49 167.8 0.2 2.5e-45 155.1 0.0 2.5 3 0 0 3 3 3 2 Amidase tRNA-synt_1g PF09334.6 EME84433.1 - 1.6e-143 478.1 0.1 2.7e-143 477.3 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EME84433.1 - 2.4e-08 32.4 0.2 1.3e-05 23.4 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME84433.1 - 0.0018 18.0 0.4 0.0046 16.7 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF2201_N PF13203.1 EME84433.1 - 0.076 12.1 2.3 0.12 11.5 1.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain UPF0547 PF10571.4 EME84433.1 - 0.96 9.2 4.1 3.3 7.4 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Ctr PF04145.10 EME84434.1 - 1.4e-30 106.2 1.1 2.2e-30 105.6 0.8 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.14 EME84435.1 - 1.2e-17 64.1 9.2 1.2e-17 64.1 6.3 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME84435.1 - 3.6e-14 52.4 0.0 9.7e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME84435.1 - 7.9e-13 48.5 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 EME84435.1 - 0.056 13.5 13.6 0.17 12.0 0.6 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) DUF334 PF03904.8 EME84437.1 - 1.2 8.3 3.1 1.8 7.8 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) TauD PF02668.11 EME84438.1 - 7.4e-48 163.4 0.0 9.2e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EME84439.1 - 1.8e-32 112.4 44.4 1.8e-31 109.1 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME84439.1 - 0.00087 17.6 3.4 0.0016 16.7 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RRM_1 PF00076.17 EME84440.1 - 5.4e-16 57.9 0.0 9.1e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84440.1 - 1.5e-14 53.6 0.0 2.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME84440.1 - 1.6e-05 24.6 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EME84440.1 - 0.00081 17.3 0.3 0.00087 17.2 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EME84440.1 - 0.15 12.3 1.9 0.27 11.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 EME84440.1 - 0.15 12.3 0.2 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 EME84440.1 - 0.21 11.0 2.6 0.37 10.3 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator HrpA_pilin PF09589.5 EME84440.1 - 0.26 11.7 1.7 0.47 10.9 1.2 1.5 1 1 0 1 1 1 0 HrpA pilus formation protein Troponin PF00992.15 EME84440.1 - 0.92 9.5 7.5 1.3 9.1 5.2 1.2 1 0 0 1 1 1 0 Troponin Glyco_hydro_25 PF01183.15 EME84441.1 - 1.5e-37 129.1 0.4 1.7e-37 129.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Ion_trans PF00520.26 EME84442.1 - 2.1e-07 30.3 6.1 3.1e-07 29.8 4.2 1.2 1 0 0 1 1 1 1 Ion transport protein DUF3333 PF11812.3 EME84442.1 - 0.038 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) PKD_channel PF08016.7 EME84442.1 - 0.16 10.3 1.5 0.18 10.1 0.2 1.6 2 0 0 2 2 2 0 Polycystin cation channel Herpes_LMP1 PF05297.6 EME84442.1 - 7.9 5.2 6.2 9.8 4.9 4.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF647 PF04884.9 EME84443.1 - 1.3e-82 276.7 6.7 1.2e-79 267.0 4.7 2.2 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF204 PF02659.10 EME84443.1 - 0.11 12.6 1.9 0.47 10.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF Steroid_dh PF02544.11 EME84444.1 - 7.2e-18 64.7 3.4 9.7e-18 64.3 0.2 2.4 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EME84444.1 - 0.032 13.5 0.3 0.055 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Fungal_trans PF04082.13 EME84445.1 - 1.1e-23 83.4 0.2 1.1e-22 80.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME84445.1 - 0.0095 15.8 5.6 0.0095 15.8 3.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EME84445.1 - 0.3 11.3 2.5 0.51 10.6 1.8 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DHquinase_I PF01487.10 EME84446.1 - 1.1e-60 205.0 0.0 1.9e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase eIF_4G1 PF12152.3 EME84447.1 - 4.2 7.3 6.4 0.59 10.0 0.6 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 Lyase_1 PF00206.15 EME84448.1 - 3.2e-92 309.0 0.0 4.1e-92 308.7 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EME84448.1 - 5e-26 90.5 0.0 1.4e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Vfa1 PF08432.5 EME84449.1 - 7.6e-45 153.1 21.7 9.8e-45 152.8 15.0 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.5 EME84449.1 - 0.0025 17.1 20.6 0.0029 16.9 14.2 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 ARGLU PF15346.1 EME84449.1 - 0.033 13.9 38.3 0.057 13.1 26.6 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 SGT1 PF07093.6 EME84449.1 - 0.053 11.8 12.6 0.065 11.6 8.7 1.1 1 0 0 1 1 1 0 SGT1 protein DUF262 PF03235.9 EME84449.1 - 0.13 12.2 4.9 0.14 12.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 CPSF73-100_C PF11718.3 EME84449.1 - 1.6 8.0 9.3 2.7 7.2 6.5 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4407 PF14362.1 EME84449.1 - 3.6 6.4 15.0 5 5.9 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 EME84449.1 - 5 5.2 21.9 5.7 5.0 15.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein F-box PF00646.28 EME84450.1 - 0.046 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain zf-C2H2_4 PF13894.1 EME84451.1 - 8.6e-06 25.7 21.1 0.32 11.4 0.2 4.9 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EME84451.1 - 0.00048 20.2 20.1 0.012 15.9 0.6 5.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME84451.1 - 0.004 17.3 0.4 0.004 17.3 0.3 4.6 4 1 0 4 4 4 1 Zinc-finger double domain zf-CHCC PF10276.4 EME84451.1 - 0.12 12.2 3.9 5.6 6.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 EME84451.1 - 1.1 9.4 10.2 0.12 12.5 0.7 3.2 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EME84451.1 - 4.8 7.0 9.4 2.4 7.9 0.6 3.5 3 0 0 3 3 3 0 BED zinc finger DSPc PF00782.15 EME84452.1 - 5.7e-25 87.4 0.0 8.5e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EME84452.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family ANTAR PF03861.9 EME84452.1 - 0.062 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain Terminase_GpA PF05876.7 EME84452.1 - 0.081 11.2 0.3 0.14 10.4 0.2 1.4 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Mu-like_Com PF10122.4 EME84452.1 - 0.32 10.0 3.2 1.2 8.2 0.2 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Chorismate_synt PF01264.16 EME84454.1 - 1.9e-128 427.7 0.0 2.3e-128 427.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Pkinase PF00069.20 EME84457.1 - 9.5e-52 175.7 0.0 1.4e-51 175.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84457.1 - 9.3e-24 83.8 0.0 3e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME84457.1 - 5.7e-09 35.3 0.0 9.5e-09 34.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like cwf18 PF08315.7 EME84458.1 - 5.5e-39 133.5 12.8 5.5e-39 133.5 8.9 2.1 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor Period_C PF12114.3 EME84458.1 - 7.6 6.0 11.7 4.6 6.7 0.8 3.1 2 1 1 3 3 3 0 Period protein 2/3C-terminal region PPR_2 PF13041.1 EME84459.1 - 1.2e-21 76.4 1.1 1.9e-10 40.5 0.0 5.0 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.1 EME84459.1 - 1.9e-13 49.5 2.7 0.00022 21.2 0.0 7.7 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 EME84459.1 - 7.3e-11 41.2 0.0 0.0015 18.3 0.0 4.7 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EME84459.1 - 9e-11 41.0 0.0 0.00027 20.3 0.0 3.7 3 0 0 3 3 3 3 PPR repeat Y_phosphatase2 PF03162.8 EME84460.1 - 5.5e-36 123.4 0.0 7.2e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EME84460.1 - 2.4e-07 31.1 0.0 5.9e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EME84460.1 - 0.00026 20.5 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME84460.1 - 0.00072 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BDM PF10684.4 EME84460.1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein PTPlike_phytase PF14566.1 EME84460.1 - 0.13 12.2 0.4 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Ras PF00071.17 EME84462.1 - 2.5e-55 186.2 0.0 3e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME84462.1 - 1.6e-15 57.6 0.0 2.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME84462.1 - 4.6e-07 29.2 0.0 7.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME84462.1 - 0.0016 17.8 0.1 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EME84462.1 - 0.0019 17.4 0.0 0.0033 16.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EME84462.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EME84462.1 - 0.014 14.8 0.0 3 7.3 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1212 PF06738.7 EME84464.1 - 2.7e-49 167.2 16.5 1.2e-47 161.9 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EME84464.1 - 2.5e-28 98.5 13.1 2.5e-28 98.5 9.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3815) Peptidase_A8 PF01252.13 EME84464.1 - 0.14 11.7 3.3 0.74 9.4 2.3 2.1 1 1 0 1 1 1 0 Signal peptidase (SPase) II DUF2301 PF10063.4 EME84464.1 - 0.51 10.5 4.7 0.24 11.6 1.1 2.1 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Zn_clus PF00172.13 EME84468.1 - 2e-10 40.4 4.9 3.1e-10 39.7 3.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME84468.1 - 3e-05 22.8 0.1 4.3e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Isochorismatase PF00857.15 EME84469.1 - 9.4e-44 149.3 0.0 1.2e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family RRM_1 PF00076.17 EME84470.1 - 3.1e-17 61.9 0.0 4.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84470.1 - 7.7e-12 45.0 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME84470.1 - 6.1e-07 29.1 0.0 9.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EME84470.1 - 0.029 14.8 15.8 0.029 14.8 10.9 4.4 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DUF3635 PF12330.3 EME84471.1 - 5.8e-09 35.9 6.0 1.5e-07 31.4 4.2 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) Spermine_synth PF01564.12 EME84472.1 - 0.00027 19.9 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EME84472.1 - 0.093 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EME84473.1 - 2.2e-51 174.5 0.0 2.9e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84473.1 - 9.7e-25 87.1 0.0 5.3e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME84473.1 - 0.00059 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME84473.1 - 0.0033 16.5 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease_2 PF13520.1 EME84474.1 - 2.9e-30 105.1 54.2 2.3e-28 98.8 24.0 3.0 2 1 1 3 3 3 3 Amino acid permease DUF1270 PF06900.6 EME84474.1 - 0.73 10.0 9.4 0.13 12.4 1.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1270) MFS_1 PF07690.11 EME84476.1 - 9.8e-27 93.5 24.3 9.8e-27 93.5 16.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily YTH PF04146.10 EME84477.1 - 8.6e-14 51.3 0.0 2.8e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 YT521-B-like domain CTK3 PF12243.3 EME84478.1 - 1.9e-50 170.1 0.0 3.2e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EME84478.1 - 1.3e-21 76.3 9.8 2.9e-21 75.2 6.8 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus OCD_Mu_crystall PF02423.10 EME84479.1 - 1.2e-12 47.2 0.0 9.7e-07 27.8 0.0 3.6 4 0 0 4 4 4 2 Ornithine cyclodeaminase/mu-crystallin family Carb_kinase PF01256.12 EME84479.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase MEKHLA PF08670.6 EME84479.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 MEKHLA domain MAPEG PF01124.13 EME84481.1 - 5.6e-20 71.2 0.6 6.7e-20 71.0 0.4 1.0 1 0 0 1 1 1 1 MAPEG family EF1G PF00647.14 EME84482.1 - 0.035 13.8 1.8 0.65 9.7 0.7 2.3 1 1 1 2 2 2 0 Elongation factor 1 gamma, conserved domain FlaC_arch PF05377.6 EME84482.1 - 0.048 13.5 7.7 5.6 6.9 0.2 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Qn_am_d_aIII PF09099.5 EME84482.1 - 0.07 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Noelin-1 PF12308.3 EME84482.1 - 0.13 12.1 1.4 0.83 9.4 0.0 2.3 2 1 0 2 2 2 0 Neurogenesis glycoprotein Spc7 PF08317.6 EME84482.1 - 0.13 10.8 16.5 0.17 10.5 5.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein MbeD_MobD PF04899.7 EME84482.1 - 0.14 12.0 5.8 1 9.3 0.9 3.2 1 1 1 2 2 2 0 MbeD/MobD like DUF883 PF05957.8 EME84482.1 - 0.16 12.4 8.0 0.5 10.7 1.1 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Transposase_22 PF02994.9 EME84482.1 - 0.24 9.8 12.3 0.71 8.3 3.5 2.1 1 1 1 2 2 2 0 L1 transposable element TFR_dimer PF04253.10 EME84482.1 - 0.27 10.8 4.4 1 8.9 0.1 2.8 1 1 2 3 3 3 0 Transferrin receptor-like dimerisation domain IncA PF04156.9 EME84482.1 - 0.31 10.6 16.2 13 5.2 11.2 2.1 1 1 0 1 1 1 0 IncA protein Rgp1 PF08737.5 EME84482.1 - 0.34 9.9 3.9 0.23 10.5 1.8 1.4 1 1 0 1 1 1 0 Rgp1 YtxH PF12732.2 EME84482.1 - 0.44 10.9 8.0 4.9 7.5 0.8 2.4 2 0 0 2 2 2 0 YtxH-like protein PTS_IIA PF02255.11 EME84482.1 - 0.67 9.8 5.5 0.51 10.2 2.8 1.7 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_MLP1_2 PF07926.7 EME84482.1 - 1.1 8.9 17.7 0.17 11.6 3.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 EME84482.1 - 1.5 8.8 10.5 0.79 9.7 0.9 3.0 1 1 2 3 3 3 0 FlxA-like protein TMF_DNA_bd PF12329.3 EME84482.1 - 1.8 8.4 16.1 0.12 12.1 3.3 2.9 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FliD_N PF02465.13 EME84482.1 - 2.1 8.7 7.9 7 7.0 0.4 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4140 PF13600.1 EME84482.1 - 2.3 8.6 7.5 4.9 7.6 1.5 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Erp_C PF06780.6 EME84482.1 - 2.9 7.7 10.9 0.42 10.4 2.9 2.1 1 1 1 2 2 2 0 Erp protein C-terminus Seryl_tRNA_N PF02403.17 EME84482.1 - 4 7.4 15.8 5.4 7.0 3.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.8 EME84482.1 - 4.5 6.2 11.2 1.3 8.0 3.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF3972 PF13118.1 EME84482.1 - 6.2 6.9 12.7 1.2 9.2 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) Cep57_MT_bd PF06657.8 EME84482.1 - 6.7 6.7 8.8 9.5 6.2 0.3 3.3 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.5 EME84482.1 - 9.2 6.3 7.8 67 3.5 5.4 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 EME84482.1 - 9.3 6.1 17.5 15 5.4 2.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Sec7 PF01369.15 EME84483.1 - 3.5e-39 134.4 0.0 6.1e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EME84483.1 - 3.5e-07 30.3 0.2 1e-06 28.8 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EME84483.1 - 1.2e-05 25.4 0.1 3.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.19 EME84484.1 - 4.8e-64 216.6 0.0 7.1e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Abhydrolase_1 PF00561.15 EME84485.1 - 3.3e-45 154.4 0.3 2.3e-44 151.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME84485.1 - 4.9e-14 52.7 0.6 5.2e-13 49.4 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EME84485.1 - 0.00066 19.5 0.1 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_5 PF12695.2 EME84485.1 - 0.0015 18.2 0.1 0.032 14.0 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EME84485.1 - 0.0028 16.3 0.0 0.0039 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Lipase_GDSL_2 PF13472.1 EME84486.1 - 5.2e-08 33.2 0.0 8.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME84486.1 - 2.5e-07 30.7 0.0 4.9e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Iso_dh PF00180.15 EME84488.1 - 4e-89 298.9 0.0 4.4e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S5_C PF03719.10 EME84488.1 - 0.049 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain OCD_Mu_crystall PF02423.10 EME84489.1 - 6.3e-08 31.7 0.0 7.1e-05 21.7 0.0 2.5 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EME84489.1 - 1.3e-06 28.5 0.0 3.5e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EME84489.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Peptidase_S24 PF00717.18 EME84490.1 - 1.4e-06 27.8 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EME84490.1 - 1.6e-06 27.6 0.0 0.00035 20.0 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF1199 PF06712.6 EME84491.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Ebp2 PF05890.7 EME84492.1 - 2.1e-66 224.0 9.3 2.1e-66 224.0 6.5 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Daxx PF03344.10 EME84492.1 - 0.16 10.4 30.8 0.22 9.9 21.4 1.1 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 EME84492.1 - 0.18 11.6 13.5 0.34 10.7 9.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rtf2 PF04641.7 EME84492.1 - 4.1 6.5 28.5 2.6 7.1 4.0 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger adh_short PF00106.20 EME84493.1 - 3.6e-18 66.0 0.1 5.7e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME84493.1 - 4.5e-12 46.0 0.0 8.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84493.1 - 2.6e-06 27.0 0.0 8.2e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME84493.1 - 0.00092 18.1 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EME84493.1 - 0.0032 16.2 0.0 0.0047 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 EME84493.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EME84493.1 - 0.074 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Pyridox_ox_2 PF12900.2 EME84494.1 - 2.9e-36 124.4 0.0 3.9e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase COX7a PF02238.10 EME84495.1 - 0.0041 16.8 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa DUF3658 PF12395.3 EME84495.1 - 0.028 13.9 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF1777 PF08648.7 EME84496.1 - 0.93 9.2 36.2 1.8 8.2 25.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EME84496.1 - 3 6.2 16.8 4.2 5.7 11.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Annexin PF00191.15 EME84497.1 - 1.7e-70 232.7 12.2 1.3e-19 69.8 0.1 4.1 4 0 0 4 4 4 4 Annexin WW PF00397.21 EME84497.1 - 4.7e-08 32.7 0.8 8.5e-08 31.9 0.6 1.5 1 0 0 1 1 1 1 WW domain Acetyltransf_11 PF13720.1 EME84497.1 - 0.13 12.5 4.5 18 5.6 0.0 3.8 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RRM_1 PF00076.17 EME84501.1 - 5.9e-17 61.0 0.0 5.3e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84501.1 - 8.8e-11 41.6 0.0 4.5e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EME84503.1 - 1.2e-38 129.6 12.1 3.8e-10 39.2 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EME84503.1 - 0.0075 14.4 0.1 0.44 8.6 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 EME84503.1 - 0.032 13.5 0.1 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature NUDE_C PF04880.8 EME84504.1 - 2.9e-12 47.2 10.9 2.9e-12 47.2 7.6 2.4 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EME84504.1 - 0.00054 18.5 26.6 0.0007 18.1 18.4 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ERM PF00769.14 EME84504.1 - 0.00093 18.7 12.7 0.00093 18.7 8.8 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family RTBV_P46 PF06216.6 EME84504.1 - 0.0055 15.6 13.5 0.015 14.1 0.3 2.3 1 1 1 2 2 2 2 Rice tungro bacilliform virus P46 protein LPP PF04728.8 EME84504.1 - 0.015 15.0 0.6 0.04 13.7 0.3 1.9 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF904 PF06005.7 EME84504.1 - 0.029 14.6 3.6 0.029 14.6 2.5 3.5 1 1 3 4 4 2 0 Protein of unknown function (DUF904) MAD PF05557.8 EME84504.1 - 0.12 10.3 26.6 0.33 8.9 18.4 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.7 EME84504.1 - 0.49 10.1 4.7 0.96 9.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Chibby PF14645.1 EME84504.1 - 0.62 9.9 13.4 1.2 9.0 5.1 2.5 1 1 0 2 2 2 0 Chibby family Tropomyosin_1 PF12718.2 EME84504.1 - 0.8 9.5 39.4 0.12 12.1 20.1 2.8 1 1 1 2 2 2 0 Tropomyosin like WXG100 PF06013.7 EME84504.1 - 1.5 8.9 10.8 0.44 10.5 5.0 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ADIP PF11559.3 EME84504.1 - 2 8.3 29.5 1.2 9.0 5.9 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EME84504.1 - 2.3 7.7 29.8 4.1 6.9 10.8 2.2 1 1 1 2 2 2 0 IncA protein FliD_N PF02465.13 EME84504.1 - 2.4 8.5 11.5 21 5.5 5.8 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Colicin-DNase PF12639.2 EME84504.1 - 2.8 8.2 6.3 5.9 7.1 3.3 2.1 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Fib_alpha PF08702.5 EME84504.1 - 3.7 7.6 14.1 6.3 6.9 3.7 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ACC_central PF08326.7 EME84505.1 - 4.1e-246 818.5 0.0 5.1e-246 818.2 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EME84505.1 - 2.6e-176 586.8 0.0 3.6e-176 586.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EME84505.1 - 4.1e-52 176.5 0.1 8.5e-52 175.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME84505.1 - 5.6e-24 84.3 0.1 1.6e-23 82.9 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EME84505.1 - 7e-23 80.6 0.0 1.4e-20 73.2 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EME84505.1 - 9.3e-16 57.2 0.2 2.6e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EME84505.1 - 6e-11 42.4 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME84505.1 - 2.1e-08 33.3 0.0 3.8e-06 25.8 0.0 3.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EME84505.1 - 1.5e-05 24.4 0.1 4.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EME84505.1 - 0.0008 19.3 0.1 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EME84505.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EME84505.1 - 0.0068 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.1 EME84505.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Acetyltransf_9 PF13527.1 EME84506.1 - 8.4e-10 38.5 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME84506.1 - 2.2e-09 37.1 0.0 4.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME84506.1 - 1.7e-07 31.2 0.0 4.1e-07 30.0 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME84506.1 - 7.2e-06 26.1 0.0 2.9e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME84506.1 - 0.0083 15.8 0.1 0.024 14.3 0.1 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EME84506.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Epimerase PF01370.16 EME84507.1 - 2e-22 79.7 0.0 4.7e-22 78.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME84507.1 - 3.1e-11 42.6 0.0 4.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EME84507.1 - 8.8e-11 41.2 0.3 3.2e-06 26.2 0.0 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EME84507.1 - 2.7e-09 36.3 0.2 2.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EME84507.1 - 5.3e-08 31.9 0.0 4.2e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EME84507.1 - 0.00024 21.0 0.2 0.047 13.5 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EME84507.1 - 0.00052 19.7 0.9 0.005 16.5 0.0 2.3 2 1 0 2 2 2 1 KR domain COesterase PF00135.23 EME84509.1 - 2e-76 257.8 0.0 2.4e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME84509.1 - 6e-05 22.7 0.1 0.00045 19.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DJ-1_PfpI PF01965.19 EME84510.1 - 3.1e-23 81.8 0.0 4.9e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EME84510.1 - 6.4e-14 51.2 0.0 1.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EME84510.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative amidotransferase Neurensin PF14927.1 EME84511.1 - 0.1 12.0 0.9 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Neurensin NMN_transporter PF04973.7 EME84511.1 - 2.7 7.3 8.2 0.074 12.4 1.4 1.5 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter Flavoprotein PF02441.14 EME84512.1 - 7.2e-40 135.6 0.1 3.1e-39 133.6 0.0 2.0 2 0 0 2 2 2 1 Flavoprotein Glutaredoxin PF00462.19 EME84513.1 - 5.2e-16 58.3 0.0 8.2e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 4HBT PF03061.17 EME84514.1 - 5.1e-13 48.9 0.0 5.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME84514.1 - 0.00037 20.3 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily EamA PF00892.15 EME84515.1 - 3.9e-17 62.4 25.3 8.4e-11 42.0 7.3 2.6 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EME84515.1 - 0.0037 17.4 24.8 0.14 12.3 4.8 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Guanylate_kin PF00625.16 EME84516.1 - 2.9e-64 215.8 0.0 3.6e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EME84516.1 - 7.9e-09 35.5 0.1 2.1e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME84516.1 - 1.7e-08 34.8 0.0 4.4e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME84516.1 - 6.2e-06 27.0 0.1 1.7e-05 25.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EME84516.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EME84516.1 - 2.8e-05 24.1 0.0 4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EME84516.1 - 3.8e-05 22.9 0.0 0.0003 20.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME84516.1 - 5.3e-05 23.3 0.1 0.00039 20.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EME84516.1 - 0.00022 21.2 0.0 0.0035 17.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 EME84516.1 - 0.0011 19.2 0.0 0.0016 18.6 0.0 1.6 1 1 0 1 1 1 1 ABC transporter CPT PF07931.7 EME84516.1 - 0.0032 17.1 0.0 0.0063 16.1 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 EME84516.1 - 0.0047 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EME84516.1 - 0.008 16.0 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME84516.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EME84516.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EME84516.1 - 0.012 15.3 0.0 0.031 13.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.12 EME84516.1 - 0.014 14.7 0.2 0.59 9.4 0.2 2.2 1 1 0 1 1 1 0 Thymidylate kinase DUF2075 PF09848.4 EME84516.1 - 0.019 13.9 0.1 3.6 6.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EME84516.1 - 0.021 13.7 0.0 0.047 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 EME84516.1 - 0.021 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EME84516.1 - 0.023 14.4 0.3 0.054 13.1 0.2 1.9 1 1 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EME84516.1 - 0.023 13.7 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ADK PF00406.17 EME84516.1 - 0.024 14.5 0.1 2.9 7.7 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase AAA_10 PF12846.2 EME84516.1 - 0.04 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EME84516.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EME84516.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EME84516.1 - 0.057 13.1 0.0 0.078 12.6 0.0 1.5 1 1 0 1 1 1 0 NTPase cobW PF02492.14 EME84516.1 - 0.065 12.6 0.1 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EME84516.1 - 0.085 13.3 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein PRK PF00485.13 EME84516.1 - 0.088 12.3 0.0 0.25 10.8 0.0 1.8 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EME84516.1 - 0.11 12.0 0.0 0.48 9.9 0.0 2.0 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EME84516.1 - 0.12 11.8 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EME84516.1 - 0.13 12.4 0.0 0.42 10.8 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EME84516.1 - 0.16 12.2 2.2 1.2 9.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 EME84517.1 - 2.5e-07 30.5 12.3 4e-07 29.8 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin_2 PF14523.1 EME84518.1 - 6e-21 74.3 10.6 1.1e-20 73.5 0.1 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EME84518.1 - 1.6e-17 62.9 6.5 1.6e-17 62.9 4.5 2.4 2 0 0 2 2 2 1 SNARE domain DUF2580 PF10824.3 EME84518.1 - 0.0003 21.0 0.8 0.0003 21.0 0.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2580) Synaptobrevin PF00957.16 EME84518.1 - 0.0012 18.3 1.1 0.0057 16.2 0.6 2.2 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 EME84518.1 - 0.048 13.1 7.7 0.3 10.5 4.3 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YjgP_YjgQ PF03739.9 EME84518.1 - 0.16 10.6 1.0 0.24 10.1 0.7 1.5 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1664 PF07889.7 EME84518.1 - 0.35 10.6 2.4 5.5 6.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF883 PF05957.8 EME84518.1 - 0.36 11.2 15.4 2.2 8.7 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Spectrin PF00435.16 EME84518.1 - 0.4 10.9 8.6 0.24 11.7 2.1 2.7 2 1 1 3 3 3 0 Spectrin repeat Spc7 PF08317.6 EME84518.1 - 0.43 9.1 8.2 1.3 7.6 4.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF912 PF06024.7 EME84518.1 - 0.44 10.6 2.2 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 EME84518.1 - 0.55 10.5 3.0 0.89 9.8 0.0 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Laminin_II PF06009.7 EME84518.1 - 0.58 9.9 7.7 1.2 8.8 0.7 3.2 2 1 2 4 4 4 0 Laminin Domain II Ndc1_Nup PF09531.5 EME84519.1 - 1.1e-111 374.1 7.0 3.3e-111 372.5 4.9 1.7 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Peptidase_C2 PF00648.16 EME84520.1 - 4.5e-42 144.0 2.1 2e-14 53.3 0.1 3.2 2 1 1 3 3 3 3 Calpain family cysteine protease Acid_PPase PF12689.2 EME84521.1 - 9.9e-60 201.0 0.0 1.2e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EME84521.1 - 0.02 15.1 1.6 0.22 11.7 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 EME84522.1 - 4e-57 188.1 18.8 2.6e-10 39.7 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EME84522.1 - 8.4e-10 38.2 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME84522.1 - 3.3e-07 29.7 0.0 6.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EME84522.1 - 0.00031 20.2 3.3 0.013 14.9 1.2 3.3 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EME84522.1 - 0.00041 18.6 8.0 1.1 7.3 0.2 5.4 4 2 2 6 6 6 3 Nucleoporin Nup120/160 DUF2428 PF10350.4 EME84523.1 - 2.4e-57 193.8 0.1 6e-57 192.5 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 EME84523.1 - 0.00023 21.4 11.9 7.7 6.8 0.0 6.3 6 0 0 6 6 6 3 HEAT repeats HEAT PF02985.17 EME84523.1 - 0.019 15.0 16.0 2.7 8.3 0.1 6.2 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 EME84523.1 - 4.8 7.7 18.4 11 6.6 0.1 6.7 6 0 0 6 6 6 0 HEAT-like repeat Tim17 PF02466.14 EME84524.1 - 3.5e-28 98.2 5.2 4.4e-28 97.8 3.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Drf_GBD PF06371.8 EME84527.1 - 1.2e-17 63.8 0.4 3.3e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EME84527.1 - 0.0022 17.4 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain Se-cys_synth_N PF12390.3 EME84527.1 - 0.13 12.4 0.1 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Selenocysteine synthase N terminal adh_short PF00106.20 EME84528.1 - 5.7e-23 81.6 0.0 7.3e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84528.1 - 1.6e-06 28.1 0.0 2.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84528.1 - 7.9e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EME84528.1 - 0.054 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EME84528.1 - 0.078 12.7 0.2 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pkinase PF00069.20 EME84529.1 - 4.7e-47 160.3 0.0 6.1e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84529.1 - 6e-28 97.6 0.0 8.8e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_23 PF13489.1 EME84530.1 - 2e-14 53.6 0.0 3.7e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME84530.1 - 1.6e-13 50.9 0.0 2.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME84530.1 - 8.6e-13 48.8 0.0 1.4e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME84530.1 - 5.2e-12 45.6 0.0 6.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME84530.1 - 7.8e-12 45.5 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME84530.1 - 1.4e-09 38.1 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME84530.1 - 3.1e-09 36.2 0.0 4.6e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME84530.1 - 1e-07 32.0 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EME84530.1 - 5.1e-06 26.5 0.0 7.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EME84530.1 - 0.00031 20.1 0.0 0.00059 19.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.11 EME84530.1 - 0.0027 16.6 0.0 0.0047 15.8 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme PrmA PF06325.8 EME84530.1 - 0.0091 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.7 EME84530.1 - 0.01 15.1 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.1 EME84530.1 - 0.022 14.4 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EME84530.1 - 0.051 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 EME84530.1 - 0.056 12.1 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) FmrO PF07091.6 EME84530.1 - 0.058 12.3 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 EME84530.1 - 0.062 12.3 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase F-box PF00646.28 EME84531.1 - 9.4e-05 21.9 0.0 0.00027 20.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME84531.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 F-box-like Lyase_1 PF00206.15 EME84532.1 - 0.0022 17.2 0.3 0.0024 17.1 0.2 1.0 1 0 0 1 1 1 1 Lyase DUF1147 PF06615.6 EME84533.1 - 0.14 12.0 0.1 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Pkinase PF00069.20 EME84534.1 - 1e-69 234.5 0.0 1.4e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME84534.1 - 6.8e-38 130.2 0.0 9.7e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME84534.1 - 0.00077 18.5 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ApbA PF02558.11 EME84535.1 - 3e-31 107.8 0.0 4.5e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EME84535.1 - 1.3e-23 83.3 0.0 1e-22 80.4 0.0 2.2 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.17 EME84535.1 - 0.031 14.7 0.0 0.099 13.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Acyltransferase PF01553.16 EME84536.1 - 0.0015 17.9 0.0 0.012 15.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 EME84537.1 - 1.4e-84 283.6 0.5 1.4e-84 283.6 0.4 2.3 2 1 0 2 2 2 1 Kinesin motor domain PspA_IM30 PF04012.7 EME84537.1 - 0.00071 19.0 8.6 0.00071 19.0 6.0 3.4 1 1 2 3 3 3 1 PspA/IM30 family DUF3584 PF12128.3 EME84537.1 - 0.0052 14.1 32.1 0.01 13.2 22.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) ERM PF00769.14 EME84537.1 - 0.03 13.8 44.7 0.24 10.9 17.6 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Filament PF00038.16 EME84537.1 - 0.034 13.6 39.7 0.51 9.7 4.6 2.4 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EME84537.1 - 0.044 12.9 19.9 0.019 14.1 2.6 3.2 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EME84537.1 - 0.2 11.4 15.0 0.029 14.2 2.1 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EME84537.1 - 0.48 9.9 29.0 0.33 10.5 8.6 3.3 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EME84537.1 - 1.7 7.1 32.3 7.8 5.0 10.3 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein UCH PF00443.24 EME84538.1 - 1.1e-40 139.4 0.0 2.5e-40 138.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME84538.1 - 4.2e-17 62.5 0.1 3.7e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase TPR_5 PF12688.2 EME84538.1 - 0.062 13.3 0.8 0.24 11.4 0.2 2.2 2 0 0 2 2 2 0 Tetratrico peptide repeat DUF2439 PF10382.4 EME84539.1 - 6.7e-26 90.3 0.0 1.3e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Sld5 PF05916.6 EME84540.1 - 6e-06 26.5 0.1 1.6e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 GINS complex protein SH3_1 PF00018.23 EME84541.1 - 7.5e-09 34.8 0.1 1.5e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EME84541.1 - 7.6e-07 28.5 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EME84541.1 - 2.5e-06 26.9 0.0 5.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Dispanin PF04505.7 EME84541.1 - 0.068 12.7 2.1 0.08 12.4 0.2 2.1 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Ribonuclease PF00545.15 EME84542.1 - 6.8e-12 45.2 0.2 8.5e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 ribonuclease Sod_Cu PF00080.15 EME84543.1 - 1.7e-44 151.4 6.9 2e-44 151.2 4.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 EME84544.1 - 9.6e-96 320.2 2.5 1.1e-95 320.0 1.7 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 EME84544.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus HET PF06985.6 EME84545.1 - 2.9e-33 114.9 0.0 3.5e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 EME84546.1 - 8e-27 93.9 0.0 8.8e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME84546.1 - 9.2e-14 51.8 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME84546.1 - 0.0014 18.1 0.1 0.035 13.5 0.0 2.8 2 2 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EME84546.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EME84546.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 EME84546.1 - 0.06 13.2 1.2 0.47 10.3 0.0 2.7 2 2 1 3 3 3 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EME84546.1 - 0.076 11.6 0.1 0.32 9.6 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.17 EME84547.1 - 6.8e-52 175.1 0.0 8e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME84547.1 - 3.2e-17 63.1 0.0 5.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME84547.1 - 5.3e-07 29.0 0.0 6.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME84547.1 - 0.00018 20.9 0.0 0.0007 19.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME84547.1 - 0.00022 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EME84547.1 - 0.024 14.6 1.4 4.6 7.1 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EME84547.1 - 0.029 14.5 0.3 0.98 9.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EME84547.1 - 0.043 13.6 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1620 PF07774.8 EME84549.1 - 1.1e-70 237.2 0.0 1.7e-70 236.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EME84549.1 - 6.4e-23 81.4 7.3 4e-21 75.5 0.6 2.9 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 EME84549.1 - 7.6e-08 31.5 0.1 0.083 12.4 0.0 4.7 4 0 0 4 4 4 3 PQQ enzyme repeat adh_short_C2 PF13561.1 EME84550.1 - 2.6e-30 105.9 0.0 3.5e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84550.1 - 3.8e-13 49.6 0.0 8.1e-13 48.6 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME84550.1 - 2.6e-06 27.2 0.1 2.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EME84550.1 - 6.5e-05 22.4 0.1 0.001 18.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME84550.1 - 0.0045 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EME84550.1 - 0.013 15.2 0.1 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 EME84550.1 - 0.019 13.6 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.14 EME84550.1 - 0.049 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 EME84550.1 - 0.086 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SNase PF00565.12 EME84551.1 - 1.6e-76 253.4 0.0 2.1e-26 92.3 0.0 5.6 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EME84551.1 - 1e-18 67.3 0.0 3.9e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EME84551.1 - 1.4e-06 27.5 0.0 2.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) SF-assemblin PF06705.6 EME84553.1 - 0.00092 18.4 4.0 0.00092 18.4 2.8 1.8 2 0 0 2 2 2 1 SF-assemblin/beta giardin AAA_13 PF13166.1 EME84553.1 - 0.0083 14.6 1.7 0.013 13.9 1.2 1.2 1 0 0 1 1 1 1 AAA domain Dynamitin PF04912.9 EME84553.1 - 0.081 11.7 4.6 0.13 11.0 2.7 1.6 1 1 0 1 1 1 0 Dynamitin DUF1664 PF07889.7 EME84553.1 - 0.23 11.2 4.7 5.1 6.9 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3287 PF11690.3 EME84553.1 - 0.28 11.2 2.7 1 9.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Fib_alpha PF08702.5 EME84553.1 - 1 9.4 3.4 3.2 7.8 1.3 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 EME84553.1 - 3.2 8.2 8.6 13 6.2 1.0 4.2 3 2 1 4 4 4 0 Syntaxin 6, N-terminal RRM_1 PF00076.17 EME84554.1 - 5.4e-15 54.7 0.0 7.9e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME84554.1 - 2.8e-11 43.2 0.0 6.1e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME84554.1 - 2.2e-07 30.5 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_67N PF03648.9 EME84556.1 - 0.0096 15.9 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DDE_1 PF03184.14 EME84556.1 - 0.013 14.6 0.1 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease PORR PF11955.3 EME84556.1 - 0.079 11.6 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain BRCT PF00533.21 EME84557.1 - 0.00022 21.2 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EME84557.1 - 0.00095 18.9 0.1 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain DUF4050 PF13259.1 EME84557.1 - 0.078 12.9 0.2 0.38 10.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4050) SNO PF01174.14 EME84558.1 - 2.1e-53 180.7 0.0 2.5e-40 138.1 0.0 3.1 3 0 0 3 3 3 3 SNO glutamine amidotransferase family GATase_3 PF07685.9 EME84558.1 - 2.6e-10 40.1 0.0 3.4e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EME84558.1 - 0.00022 20.7 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DUF4066 PF13278.1 EME84558.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EME84558.1 - 0.0032 16.9 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EME84558.1 - 0.047 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_C26 PF07722.8 EME84558.1 - 0.13 11.6 0.0 0.86 9.0 0.0 2.2 2 1 0 2 2 2 0 Peptidase C26 DUF1770 PF08589.5 EME84558.1 - 0.35 11.4 6.6 0.11 13.0 2.6 1.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) ACPS PF01648.15 EME84559.1 - 2e-07 30.8 0.0 7.9e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SSF PF00474.12 EME84560.1 - 5.2e-18 64.8 28.0 9.1e-18 64.0 19.4 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Lyase_1 PF00206.15 EME84561.1 - 2.2e-23 82.9 0.0 3.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EME84561.1 - 5.7e-15 55.0 0.0 2.8e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF4267 PF14087.1 EME84562.1 - 1.7e-14 53.3 0.1 2.1e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Acetyltransf_2 PF00797.12 EME84563.1 - 5.5e-13 49.0 0.1 2.2e-12 47.1 0.0 1.9 1 1 1 2 2 2 1 N-acetyltransferase Rop-like PF05082.8 EME84565.1 - 0.11 12.0 0.1 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Rop-like DUF948 PF06103.6 EME84565.1 - 0.16 11.8 0.0 2.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1534 PF07551.6 EME84566.1 - 0.099 12.1 1.1 0.38 10.3 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) MFS_1 PF07690.11 EME84568.1 - 4.9e-34 117.6 36.8 4.9e-34 117.6 25.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 EME84568.1 - 0.25 11.3 0.1 0.25 11.3 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) DUF3605 PF12239.3 EME84569.1 - 1.2e-55 187.7 0.2 1.4e-55 187.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) RNaseH_C PF09293.5 EME84569.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 T4 RNase H, C terminal FAD_binding_6 PF00970.19 EME84570.1 - 4.7e-26 90.8 0.1 1.1e-25 89.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EME84570.1 - 8.4e-25 87.4 0.0 1.3e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EME84570.1 - 0.003 17.4 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EME84570.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain FAD_binding_4 PF01565.18 EME84571.1 - 6.5e-23 80.7 0.2 1.1e-22 80.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME84571.1 - 0.011 15.6 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 Berberine and berberine like adh_short_C2 PF13561.1 EME84572.1 - 3.3e-25 89.2 0.3 7.3e-13 48.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84572.1 - 8.8e-24 84.2 0.1 1.2e-23 83.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME84572.1 - 3.1e-17 62.8 0.1 5e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84572.1 - 0.0087 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME84572.1 - 0.012 14.2 0.1 0.018 13.7 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_3 PF13738.1 EME84573.1 - 3.8e-21 76.1 0.0 2.6e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME84573.1 - 2.9e-17 62.0 0.0 4.9e-14 51.4 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME84573.1 - 1.5e-12 47.1 0.0 6e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME84573.1 - 7.1e-06 25.8 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME84573.1 - 2.7e-05 24.1 0.0 6.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME84573.1 - 0.028 14.7 0.2 0.25 11.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL PF07366.7 EME84574.1 - 3.3e-05 23.4 0.0 5.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EME84574.1 - 0.0031 17.8 0.1 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF761 PF05553.6 EME84574.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Cotton fibre expressed protein SMC_N PF02463.14 EME84575.1 - 9.5e-71 237.5 7.1 2.1e-70 236.3 4.9 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME84575.1 - 8.3e-31 106.4 0.1 7.1e-30 103.4 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EME84575.1 - 1.7e-17 64.3 1.1 2.4e-08 34.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EME84575.1 - 2.6e-12 47.4 40.0 2.6e-12 47.4 27.7 7.5 2 2 3 5 5 3 1 AAA domain Reo_sigmaC PF04582.7 EME84575.1 - 7.5e-05 22.0 27.1 0.26 10.4 2.3 5.2 2 2 2 5 5 5 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 EME84575.1 - 0.00033 20.1 0.0 0.00077 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain WEMBL PF05701.6 EME84575.1 - 0.00034 19.2 29.9 0.00034 19.2 20.7 4.1 2 2 1 3 3 3 1 Weak chloroplast movement under blue light APG6 PF04111.7 EME84575.1 - 0.005 15.9 17.3 0.005 15.9 12.0 7.4 3 2 4 8 8 8 3 Autophagy protein Apg6 AAA_13 PF13166.1 EME84575.1 - 0.13 10.6 0.0 0.072 11.5 11.5 6.5 3 2 4 7 7 7 0 AAA domain DUF3584 PF12128.3 EME84575.1 - 0.2 8.9 113.8 0.18 9.1 39.8 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3584) ArsR PF09824.4 EME84575.1 - 0.74 9.1 11.9 0.12 11.7 1.3 3.9 3 1 0 3 3 3 0 ArsR transcriptional regulator DUF1664 PF07889.7 EME84575.1 - 6.8 6.5 59.7 0.072 12.8 4.0 8.1 4 2 2 7 7 7 0 Protein of unknown function (DUF1664) OmdA PF13376.1 EME84577.1 - 2.7e-11 42.9 0.4 6e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated DUF3328 PF11807.3 EME84579.1 - 2.3 7.8 6.7 11 5.6 4.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) adh_short_C2 PF13561.1 EME84580.1 - 9.1e-16 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84580.1 - 8.9e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EME84580.1 - 0.024 14.3 0.1 0.15 11.8 0.1 2.1 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EME84580.1 - 0.03 14.3 0.1 0.053 13.5 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EME84580.1 - 0.082 12.5 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 KR domain YqbF PF14553.1 EME84582.1 - 8.9e-05 22.0 18.9 3.3 7.4 0.3 6.0 1 1 5 6 6 6 5 YqbF, hypothetical protein domain DUF3704 PF12488.3 EME84582.1 - 0.00027 20.4 0.3 72 3.1 0.0 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF3704) Cornifin PF02389.10 EME84582.1 - 0.00039 20.2 0.3 0.00048 19.9 0.2 1.1 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF1971 PF09313.6 EME84582.1 - 0.0014 18.2 0.5 2.2 8.0 0.0 2.6 1 1 3 4 4 4 3 Domain of unknown function (DUF1971) YozD PF14162.1 EME84582.1 - 0.024 14.6 1.7 64 3.7 0.1 4.5 1 1 5 6 6 6 0 YozD-like protein DUF3775 PF12616.3 EME84582.1 - 0.12 12.2 0.4 44 3.9 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3775) DUF3328 PF11807.3 EME84583.1 - 1.8e-19 70.3 5.2 2.1e-19 70.0 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S8 PF00082.17 EME84584.1 - 7.7e-48 163.0 0.0 1.1e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EME84584.1 - 8.9e-12 45.4 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) ABC_tran PF00005.22 EME84586.1 - 5.3e-41 140.1 0.0 7.3e-21 74.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EME84586.1 - 3.9e-29 101.9 26.5 1.8e-25 89.8 11.5 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EME84586.1 - 1.1e-12 48.4 0.1 0.13 12.2 0.0 4.9 5 0 0 5 5 5 3 AAA domain SMC_N PF02463.14 EME84586.1 - 9.4e-08 31.5 1.0 0.05 12.8 0.1 4.7 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME84586.1 - 2.7e-07 30.0 0.3 0.0088 15.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EME84586.1 - 6.9e-07 29.7 0.4 0.038 14.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EME84586.1 - 1.5e-06 28.5 0.0 0.0031 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EME84586.1 - 1.8e-06 27.0 0.0 0.0024 16.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EME84586.1 - 4e-06 27.6 0.0 0.094 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EME84586.1 - 7.6e-06 25.8 0.0 0.045 13.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 EME84586.1 - 8.9e-06 25.6 0.5 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EME84586.1 - 5.3e-05 23.3 0.4 0.84 9.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EME84586.1 - 5.5e-05 22.6 0.2 0.0077 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME84586.1 - 7.6e-05 22.7 0.1 0.37 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EME84586.1 - 8.2e-05 22.1 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EME84586.1 - 0.00012 21.9 0.1 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 EME84586.1 - 0.00022 20.9 0.1 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EME84586.1 - 0.00062 19.6 0.0 0.57 10.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EME84586.1 - 0.0019 17.6 4.7 0.23 10.8 0.0 3.4 4 0 0 4 4 3 1 AAA-like domain Adeno_IVa2 PF02456.10 EME84586.1 - 0.0043 15.7 0.1 2.3 6.7 0.0 2.3 2 0 0 2 2 2 2 Adenovirus IVa2 protein Miro PF08477.8 EME84586.1 - 0.011 16.2 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EME84586.1 - 0.011 15.9 0.2 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EME84586.1 - 0.011 14.9 0.0 5.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EME84586.1 - 0.043 13.9 0.1 12 6.0 0.0 3.1 3 0 0 3 3 3 0 RNA helicase PduV-EutP PF10662.4 EME84586.1 - 0.067 12.6 0.3 2.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EME84586.1 - 0.071 12.5 0.0 16 4.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.1 EME84586.1 - 0.078 12.9 0.2 4.2 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME84586.1 - 0.089 12.6 0.0 13 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EME84586.1 - 0.091 12.4 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 EME84586.1 - 0.12 12.0 0.8 19 4.9 0.0 3.1 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.12 EME84586.1 - 0.13 11.7 0.1 4.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EME84586.1 - 0.23 10.5 0.1 6.5 5.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin DEAD PF00270.24 EME84586.1 - 0.27 10.7 1.6 5.7 6.4 0.0 3.4 5 0 0 5 5 4 0 DEAD/DEAH box helicase adh_short_C2 PF13561.1 EME84587.1 - 5.3e-30 104.9 0.0 7.1e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84587.1 - 3.4e-23 82.3 0.4 5.4e-23 81.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME84587.1 - 2.8e-13 49.9 0.4 4.8e-13 49.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84587.1 - 0.004 16.6 0.1 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME84587.1 - 0.061 12.0 0.1 0.086 11.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.21 EME84587.1 - 0.074 12.5 0.6 7.3 6.1 0.0 2.4 1 1 1 2 2 2 0 Zinc-binding dehydrogenase RTC PF01137.16 EME84588.1 - 9.9e-46 155.3 0.0 1.3e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Serglycin PF04360.7 EME84589.1 - 0.0049 16.5 0.1 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Serglycin Asparaginase PF00710.15 EME84591.1 - 6.7e-93 310.9 0.0 8.5e-93 310.6 0.0 1.0 1 0 0 1 1 1 1 Asparaginase IMS PF00817.15 EME84592.1 - 1.7e-41 141.4 0.0 2.8e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EME84592.1 - 1.1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Aa_trans PF01490.13 EME84593.1 - 3.8e-72 243.0 18.0 4.2e-72 242.8 12.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 EME84593.1 - 0.0049 16.5 0.9 0.0049 16.5 0.6 2.9 3 1 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction CAAD PF14159.1 EME84593.1 - 2.4 7.8 6.7 0.4 10.3 0.3 3.0 4 0 0 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Thioredoxin PF00085.15 EME84594.1 - 2.6e-24 84.8 0.0 3.7e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME84594.1 - 6.4e-06 26.1 0.1 0.00015 21.7 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EME84594.1 - 1.6e-05 25.0 0.3 0.00014 21.9 0.2 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EME84594.1 - 4.2e-05 23.4 0.0 7.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EME84594.1 - 0.0091 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EME84594.1 - 0.014 14.9 0.2 0.072 12.6 0.1 1.8 1 1 1 2 2 2 0 Redoxin AhpC-TSA PF00578.16 EME84594.1 - 0.028 14.1 0.1 0.084 12.5 0.1 1.7 1 1 1 2 2 2 0 AhpC/TSA family DUF2931 PF11153.3 EME84596.1 - 0.085 12.1 0.2 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) p450 PF00067.17 EME84599.1 - 7.5e-61 206.0 0.0 8.9e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_7 PF13499.1 EME84600.1 - 9.1e-19 67.3 0.4 1.2e-11 44.5 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME84600.1 - 8.2e-17 59.1 4.7 0.00016 20.7 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EME84600.1 - 1.1e-13 49.8 6.2 5.1e-05 22.8 0.1 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EME84600.1 - 3.3e-12 45.8 5.1 6.1e-08 32.1 0.1 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EME84600.1 - 5e-06 26.3 0.0 0.00033 20.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EME84600.1 - 1.6e-05 24.0 7.6 0.0081 15.4 0.1 3.7 3 1 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EME84600.1 - 0.044 13.5 0.1 1.8 8.3 0.0 2.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Acetate_kinase PF00871.12 EME84601.1 - 3.4e-97 325.4 0.3 4.1e-97 325.1 0.2 1.0 1 0 0 1 1 1 1 Acetokinase family SNARE PF05739.14 EME84602.1 - 2e-19 69.0 2.6 2e-19 69.0 1.8 3.4 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EME84602.1 - 3e-11 43.4 0.2 3e-11 43.4 0.2 2.6 2 1 0 2 2 2 1 Syntaxin Aldedh PF00171.17 EME84602.1 - 0.087 11.1 0.2 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family DNA_repr_REX1B PF14966.1 EME84602.1 - 0.11 12.8 1.4 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 DNA repair REX1-B MCPsignal PF00015.16 EME84602.1 - 0.35 10.3 9.8 0.13 11.8 1.5 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PhoU PF01895.14 EME84602.1 - 1.1 9.7 4.4 0.87 10.0 1.0 2.1 2 0 0 2 2 2 0 PhoU domain DUF2951 PF11166.3 EME84602.1 - 1.1 9.0 6.2 0.41 10.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) EF-hand_1 PF00036.27 EME84603.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EME84603.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EME84603.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EME84603.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EME84603.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EME84603.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EME84603.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EME84603.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EME84603.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EME84603.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EME84603.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EME84603.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 EME84603.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EME84603.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EME84603.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 EME84603.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EME84603.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EME84603.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 EME84603.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain JAB PF01398.16 EME84604.1 - 0.00012 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EME84604.1 - 0.0015 18.5 0.0 0.079 13.0 0.0 2.7 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function Cupin_2 PF07883.6 EME84605.1 - 7.6e-08 31.7 0.5 7.6e-08 31.7 0.3 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EME84605.1 - 0.023 14.1 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.14 EME84605.1 - 1 9.0 3.4 0.27 10.9 0.2 1.6 2 0 0 2 2 2 0 AraC-like ligand binding domain Chromo PF00385.19 EME84608.1 - 1e-14 53.8 2.7 6.9e-07 28.8 0.1 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.1 EME84609.1 - 4e-09 36.1 2.2 2.7e-08 33.5 1.5 2.6 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME84609.1 - 4.5e-09 36.2 5.9 7.8e-09 35.5 2.7 2.5 1 1 1 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EME84609.1 - 0.00035 20.1 5.3 0.0044 16.6 3.7 2.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME84609.1 - 0.00073 19.5 4.2 0.003 17.5 0.2 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME84609.1 - 0.0011 18.7 1.0 0.0011 18.7 0.7 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 EME84609.1 - 0.0068 15.8 0.6 0.03 13.8 0.4 2.2 1 0 0 1 1 1 1 P-11 zinc finger zf-C3HC4 PF00097.20 EME84609.1 - 0.018 14.7 5.1 0.018 14.7 3.6 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME84609.1 - 0.33 10.7 4.9 4 7.2 3.4 2.6 1 1 0 1 1 1 0 zinc-RING finger domain FAD_binding_1 PF00667.15 EME84610.1 - 6.8e-48 163.0 0.0 1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EME84610.1 - 8.7e-09 35.9 0.1 6.3e-07 29.9 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Sugar_tr PF00083.19 EME84611.1 - 6.6e-106 354.5 22.9 7.9e-106 354.3 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME84611.1 - 7e-21 74.3 28.4 7.7e-14 51.1 3.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EME84612.1 - 3.1e-24 85.0 1.6 6.2e-24 84.0 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME84612.1 - 0.031 14.1 0.1 0.077 12.9 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like AAA_5 PF07728.9 EME84614.1 - 1.8e-125 413.2 2.6 1.4e-22 79.8 0.0 9.9 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EME84614.1 - 2e-28 99.2 1.6 0.00029 21.0 0.0 7.6 8 0 0 8 8 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EME84614.1 - 4.8e-28 97.3 0.0 7.1e-09 35.3 0.0 7.9 8 0 0 8 8 7 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME84614.1 - 1.4e-25 90.4 3.9 0.00095 19.9 0.0 8.0 8 0 0 8 8 6 6 AAA domain AAA_18 PF13238.1 EME84614.1 - 7.9e-22 77.9 0.9 0.044 14.1 0.0 8.0 7 0 0 7 7 7 5 AAA domain Sigma54_activat PF00158.21 EME84614.1 - 3.1e-21 75.5 0.2 0.0095 15.4 0.0 6.4 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_22 PF13401.1 EME84614.1 - 1.4e-20 73.7 3.2 0.012 15.7 0.0 8.6 7 1 0 7 7 7 5 AAA domain Sigma54_activ_2 PF14532.1 EME84614.1 - 2.7e-20 72.8 0.1 0.00064 19.7 0.0 6.3 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_14 PF13173.1 EME84614.1 - 2.5e-18 66.2 0.0 0.00062 19.6 0.0 7.4 7 0 0 7 7 6 3 AAA domain AAA_33 PF13671.1 EME84614.1 - 1.3e-17 64.0 0.1 0.24 11.2 0.0 7.4 6 1 0 6 6 6 4 AAA domain AAA_19 PF13245.1 EME84614.1 - 1.2e-16 60.2 13.4 0.027 14.2 0.1 7.7 7 0 0 7 7 7 5 Part of AAA domain AAA_16 PF13191.1 EME84614.1 - 1.6e-16 60.8 32.9 0.00015 21.7 0.3 10.7 11 0 0 11 11 9 5 AAA ATPase domain T2SE PF00437.15 EME84614.1 - 4.9e-15 55.1 5.3 0.012 14.5 0.1 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein RNA_helicase PF00910.17 EME84614.1 - 4e-13 49.4 3.4 0.086 13.0 0.0 7.1 7 0 0 7 7 6 2 RNA helicase UPF0079 PF02367.12 EME84614.1 - 4.2e-13 48.9 8.9 0.078 12.6 0.2 6.9 7 0 0 7 7 6 4 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EME84614.1 - 7.2e-13 49.0 1.7 0.0032 17.7 0.0 7.8 7 0 0 7 7 7 2 ABC transporter NACHT PF05729.7 EME84614.1 - 2.6e-12 46.7 11.6 0.1 12.2 0.0 6.5 7 0 0 7 7 5 4 NACHT domain Mg_chelatase PF01078.16 EME84614.1 - 4.6e-11 42.2 3.2 3.1 6.9 0.2 8.8 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EME84614.1 - 2.7e-10 39.6 1.5 0.32 10.1 0.0 6.2 6 0 0 6 6 6 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME84614.1 - 3.1e-10 39.4 1.5 0.74 9.3 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EME84614.1 - 4.5e-10 39.2 1.2 0.11 11.9 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.7 EME84614.1 - 1.2e-09 37.5 7.3 0.99 8.4 0.0 7.2 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EME84614.1 - 1.3e-09 37.4 5.0 0.65 9.0 0.0 6.7 6 0 0 6 6 6 2 Zeta toxin NTPase_1 PF03266.10 EME84614.1 - 2.5e-08 33.7 11.5 0.16 11.6 0.3 6.5 6 0 0 6 6 6 3 NTPase Arch_ATPase PF01637.13 EME84614.1 - 4.7e-08 33.0 0.0 1.7 8.3 0.0 6.2 6 0 0 6 6 6 1 Archaeal ATPase AAA_28 PF13521.1 EME84614.1 - 6.6e-08 32.6 12.1 0.16 11.9 0.4 6.5 6 0 0 6 6 5 1 AAA domain AAA_25 PF13481.1 EME84614.1 - 8.8e-08 31.7 10.4 0.66 9.3 0.9 6.1 5 1 0 5 5 4 3 AAA domain Miro PF08477.8 EME84614.1 - 4.8e-07 30.2 2.2 2 8.9 0.0 6.2 6 0 0 6 6 5 1 Miro-like protein MobB PF03205.9 EME84614.1 - 2.7e-06 27.1 9.8 0.19 11.4 0.1 5.9 7 0 0 7 7 5 2 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EME84614.1 - 1.8e-05 23.6 0.1 2.2 6.8 0.0 3.8 4 0 0 4 4 4 2 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EME84614.1 - 1.9e-05 23.7 2.5 0.75 8.6 0.0 5.2 5 0 0 5 5 5 1 NB-ARC domain PduV-EutP PF10662.4 EME84614.1 - 2.9e-05 23.5 5.5 0.013 14.9 0.0 4.8 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EME84614.1 - 5e-05 23.7 17.6 1 9.6 0.0 7.6 8 0 0 8 8 6 2 AAA domain TIP49 PF06068.8 EME84614.1 - 0.00015 20.5 4.4 0.31 9.7 0.0 5.5 6 0 0 6 6 6 1 TIP49 C-terminus SRP54 PF00448.17 EME84614.1 - 0.00019 20.9 10.5 0.25 10.7 0.0 5.5 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain Bac_DnaA PF00308.13 EME84614.1 - 0.00029 20.5 0.2 9.1 5.8 0.0 5.1 6 0 0 6 6 5 0 Bacterial dnaA protein AAA_7 PF12775.2 EME84614.1 - 0.00058 19.0 1.3 2.4 7.1 0.0 4.9 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 KTI12 PF08433.5 EME84614.1 - 0.00072 18.8 0.1 4.5 6.3 0.0 5.0 5 0 0 5 5 5 0 Chromatin associated protein KTI12 PhoH PF02562.11 EME84614.1 - 0.0012 18.1 3.1 3.7 6.7 0.2 4.5 4 0 0 4 4 4 0 PhoH-like protein AAA_24 PF13479.1 EME84614.1 - 0.0019 17.7 6.0 24 4.4 0.0 6.0 6 0 0 6 6 6 0 AAA domain cobW PF02492.14 EME84614.1 - 0.0031 16.9 12.0 2.4 7.5 0.2 6.0 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EME84614.1 - 0.0095 14.7 2.2 5 5.8 0.0 3.8 4 0 0 4 4 4 0 ArgK protein CbiA PF01656.18 EME84614.1 - 0.011 15.1 2.7 14 5.0 0.0 4.5 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 EME84614.1 - 0.018 14.1 2.4 10 5.1 0.0 4.5 5 0 0 5 5 5 0 KaiC ATP-synt_ab PF00006.20 EME84614.1 - 0.02 14.3 0.0 4.2 6.8 0.0 3.8 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_6 PF12774.2 EME84614.1 - 0.085 12.3 0.9 17 4.8 0.0 4.6 7 0 0 7 7 4 0 Hydrolytic ATP binding site of dynein motor region D1 Thymidylate_kin PF02223.12 EME84614.1 - 0.21 10.9 7.4 3.2 7.1 0.0 5.4 7 0 0 7 7 6 0 Thymidylate kinase AAA_21 PF13304.1 EME84614.1 - 0.36 10.7 0.0 46 3.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.15 EME84614.1 - 0.77 9.3 3.8 24 4.5 0.0 3.9 4 0 0 4 4 3 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 EME84614.1 - 2.5 7.5 16.8 1.4 8.3 0.1 5.7 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 EME84614.1 - 4.5 6.1 0.0 97 1.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_L12 PF00542.14 EME84615.1 - 2.1e-17 62.9 8.6 9e-17 60.8 4.8 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 EME84615.1 - 0.04 14.0 0.1 16 5.6 0.1 2.6 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Bindin PF02084.10 EME84615.1 - 0.045 13.8 0.1 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Bindin DEK_C PF08766.6 EME84615.1 - 0.07 12.9 1.1 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 DEK C terminal domain DUF2890 PF11081.3 EME84615.1 - 0.91 9.5 5.3 1.6 8.7 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) DUF334 PF03904.8 EME84616.1 - 1.7 7.9 10.1 3 7.1 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) GRAM PF02893.15 EME84617.1 - 8.1e-16 57.3 0.0 1.5e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF1777 PF08648.7 EME84618.1 - 0.041 13.6 14.4 0.068 12.9 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF572 PF04502.8 EME84618.1 - 0.083 12.0 15.9 0.13 11.4 11.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2895 PF11444.3 EME84618.1 - 0.095 11.9 6.4 0.022 13.9 1.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2895) Plasmodium_Vir PF05795.6 EME84618.1 - 0.2 10.8 0.1 0.31 10.1 0.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.9 EME84618.1 - 0.26 9.2 10.3 0.41 8.6 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 EME84618.1 - 0.54 9.0 9.1 1.1 8.0 6.3 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF966 PF06136.8 EME84618.1 - 1.4 8.2 12.8 2.7 7.3 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) VID27 PF08553.5 EME84618.1 - 2.3 6.3 7.2 3.1 5.9 5.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Radial_spoke_3 PF06098.6 EME84618.1 - 4.7 6.1 17.5 8.6 5.2 12.2 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Borrelia_P83 PF05262.6 EME84618.1 - 5.5 5.1 16.4 7.8 4.6 11.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF1 PF04857.15 EME84619.1 - 2.7e-49 167.8 0.0 3.4e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Cofilin_ADF PF00241.15 EME84620.1 - 2.1e-20 72.9 0.0 6.4e-11 42.2 0.0 2.3 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Lactonase PF10282.4 EME84621.1 - 8.2e-29 100.7 0.0 1.7e-28 99.7 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 EME84621.1 - 0.01 15.2 0.0 0.18 11.1 0.0 2.4 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region HTH_Tnp_Tc3_1 PF11427.3 EME84621.1 - 0.042 13.4 0.1 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Tc3 transposase Arylesterase PF01731.15 EME84621.1 - 0.07 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Arylesterase zf-RING_6 PF14835.1 EME84622.1 - 0.00042 20.0 6.7 0.00042 20.0 4.7 1.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EME84622.1 - 0.25 11.0 9.9 0.42 10.3 6.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EME84622.1 - 0.7 9.4 5.8 1.5 8.3 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 EME84622.1 - 3.1 7.9 10.5 5.2 7.1 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SGT1 PF07093.6 EME84622.1 - 3.2 6.0 11.9 4.4 5.5 8.3 1.1 1 0 0 1 1 1 0 SGT1 protein NinF PF05810.7 EME84622.1 - 3.3 7.5 7.2 5 7.0 0.4 2.6 1 1 1 2 2 2 0 NinF protein Abhydrolase_3 PF07859.8 EME84623.1 - 7.5e-26 91.0 0.0 1e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EME84623.1 - 1.5e-22 79.7 0.0 1.8e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EME84623.1 - 0.00056 18.7 0.7 0.097 11.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EME84623.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ufd2P_core PF10408.4 EME84625.1 - 8.3e-184 612.3 3.9 1e-183 612.0 2.7 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EME84625.1 - 2.3e-27 94.7 1.4 2.3e-27 94.7 1.0 2.2 2 0 0 2 2 2 1 U-box domain CTP_transf_2 PF01467.21 EME84626.1 - 0.0038 17.2 0.0 1.4 8.9 0.0 3.1 1 1 0 1 1 1 1 Cytidylyltransferase Meth_synt_2 PF01717.13 EME84627.1 - 3.4e-145 483.0 0.0 9.3e-140 465.1 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EME84627.1 - 2.7e-125 417.7 0.2 2.5e-113 378.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EME84627.1 - 0.00087 18.3 0.0 0.057 12.3 0.0 3.2 3 0 0 3 3 3 1 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.4 EME84627.1 - 0.083 12.3 1.6 0.6 9.6 0.1 3.2 3 0 0 3 3 3 0 Short C-terminal domain BTB PF00651.26 EME84630.1 - 0.0039 17.1 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_S7 PF00177.16 EME84632.1 - 2.2e-28 98.6 0.0 9.3e-28 96.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e MFS_1 PF07690.11 EME84633.1 - 1.2e-33 116.2 35.7 1.2e-33 116.2 24.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 EME84636.1 - 6.4e-08 32.3 7.9 1.2e-07 31.4 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME84636.1 - 4.4e-06 25.7 0.0 9.3e-06 24.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 EME84637.1 - 1.1e-83 280.9 0.0 1.5e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME84637.1 - 2.5e-14 53.9 0.1 6.5e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RTX_C PF08339.5 EME84637.1 - 0.014 15.1 1.0 0.17 11.6 0.3 2.3 1 1 0 2 2 2 0 RTX C-terminal domain GH3 PF03321.8 EME84637.1 - 0.04 12.4 0.0 0.35 9.3 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter TatD_DNase PF01026.16 EME84641.1 - 1.1e-53 182.0 0.0 1.4e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF2277 PF10041.4 EME84642.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) DUF1793 PF08760.6 EME84643.1 - 1.4e-43 148.6 1.1 2.2e-43 148.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EME84643.1 - 0.021 13.9 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Glyco_transf_25 PF01755.12 EME84644.1 - 1.8e-06 27.7 0.0 1.8e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Gly_transf_sug PF04488.10 EME84645.1 - 4.8e-13 49.3 0.0 9e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EME84645.1 - 0.035 13.2 0.2 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.17 EME84646.1 - 1.5e-22 79.9 34.5 3e-22 78.8 23.9 1.5 1 1 0 1 1 1 1 Acyltransferase family Glyco_transf_34 PF05637.7 EME84647.1 - 2.5e-17 63.1 0.5 2.7e-10 40.1 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EME84647.1 - 0.0011 18.3 0.1 0.0015 17.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Sars6 PF12133.3 EME84647.1 - 0.0098 15.5 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 1 Open reading frame 6 from SARS coronavirus DUF3184 PF11380.3 EME84649.1 - 0.064 11.1 0.0 0.12 10.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3184) Cas1_AcylT PF07779.7 EME84654.1 - 8.7e-72 242.1 20.4 3.1e-69 233.7 14.1 2.9 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EME84654.1 - 0.022 14.5 0.0 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p adh_short PF00106.20 EME84655.1 - 6.2e-18 65.2 2.6 4.5e-17 62.4 1.8 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84655.1 - 1.1e-16 61.3 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84655.1 - 7.8e-09 35.4 3.2 5.7e-08 32.6 0.2 2.2 1 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EME84655.1 - 0.00017 21.6 0.4 0.00038 20.5 0.2 1.6 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EME84655.1 - 0.14 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ICE2 PF08426.5 EME84656.1 - 7.4e-129 429.9 3.0 8.5e-129 429.7 2.1 1.0 1 0 0 1 1 1 1 ICE2 UPF0160 PF03690.8 EME84658.1 - 1e-117 393.1 0.0 1.3e-117 392.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) PNP_UDP_1 PF01048.15 EME84660.1 - 1.2e-15 57.1 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Bac_rhamnosid PF05592.6 EME84661.1 - 1.7e-178 594.0 0.0 2e-178 593.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EME84661.1 - 2.5e-26 92.2 0.0 5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Pyr_redox_3 PF13738.1 EME84662.1 - 1.7e-20 73.9 0.1 5.3e-20 72.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME84662.1 - 2.1e-14 52.6 0.2 1.3e-13 50.0 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME84662.1 - 1.1e-10 41.7 0.0 1.2e-08 35.0 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME84662.1 - 7e-10 38.3 2.0 2.4e-07 30.0 0.4 3.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EME84662.1 - 3.1e-06 27.5 0.1 0.1 13.0 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME84662.1 - 0.00065 19.6 0.8 0.0018 18.2 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME84662.1 - 0.00089 18.2 0.3 0.091 11.6 0.0 3.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EME84662.1 - 0.001 18.2 0.2 0.91 8.6 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EME84662.1 - 0.0014 17.9 0.1 0.0068 15.7 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 EME84662.1 - 0.0053 16.5 0.2 0.93 9.2 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EME84662.1 - 0.0085 14.9 0.0 0.32 9.7 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EME84662.1 - 0.01 14.9 3.2 0.086 11.8 0.8 2.4 1 1 1 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EME84662.1 - 0.02 13.7 0.1 0.067 12.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein KaiC PF06745.8 EME84662.1 - 0.034 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 KaiC 3HCDH_N PF02737.13 EME84662.1 - 0.035 13.7 0.2 3.3 7.3 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EME84662.1 - 0.052 12.0 0.0 0.11 10.9 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.1 EME84662.1 - 0.1 12.9 0.1 20 5.4 0.0 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.13 EME84662.1 - 0.11 12.5 0.1 0.75 9.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain E1-E2_ATPase PF00122.15 EME84663.1 - 9.3e-49 165.5 0.6 9.3e-49 165.5 0.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME84663.1 - 5.9e-38 130.2 5.8 5.9e-38 130.2 4.0 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME84663.1 - 4.3e-30 105.7 0.0 1.8e-29 103.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME84663.1 - 1.5e-18 66.5 0.0 3.6e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EME84663.1 - 5.6e-17 62.5 0.1 9.4e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME84663.1 - 1.7e-09 36.9 0.0 6.3e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EME84663.1 - 0.00016 21.3 0.2 0.00031 20.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 EME84663.1 - 0.0092 16.3 1.2 0.0092 16.3 0.8 2.6 3 0 0 3 3 3 1 Predicted membrane protein (DUF2231) DUF3592 PF12158.3 EME84663.1 - 0.53 10.0 2.2 0.63 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Sulfatase PF00884.18 EME84664.1 - 9e-10 38.2 0.0 1.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF1248 PF06852.7 EME84664.1 - 0.019 14.2 0.1 0.39 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) Sulfatase_C PF14707.1 EME84664.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Isy1 PF06246.7 EME84665.1 - 9e-87 290.6 2.7 2.5e-86 289.2 1.9 1.6 1 1 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EME84665.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 YolD-like protein HJURP_C PF12347.3 EME84667.1 - 0.14 11.7 1.3 4.7 6.8 0.0 2.2 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Uds1 PF15456.1 EME84668.1 - 2.9e-30 104.8 8.8 2.9e-30 104.8 6.1 6.7 5 1 1 6 6 6 2 Up-regulated During Septation MtrG PF04210.8 EME84668.1 - 2.7 7.7 5.5 24 4.6 0.1 3.8 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Reo_sigmaC PF04582.7 EME84668.1 - 6.3 5.8 11.5 12 4.9 0.1 3.8 2 1 0 3 3 3 0 Reovirus sigma C capsid protein MOZ_SAS PF01853.13 EME84670.1 - 2.7e-65 219.1 0.0 5.3e-65 218.1 0.0 1.5 1 1 0 1 1 1 1 MOZ/SAS family IF2_N PF04760.10 EME84670.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region He_PIG_assoc PF10632.4 EME84670.1 - 0.066 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DHFR_1 PF00186.14 EME84672.1 - 3.5e-32 111.2 0.0 5.6e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Mito_carr PF00153.22 EME84673.1 - 4.9e-70 231.3 1.7 1.7e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CN_hydrolase PF00795.17 EME84674.1 - 4.4e-24 84.8 0.0 5.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aldo_ket_red PF00248.16 EME84675.1 - 2.1e-67 226.9 0.0 2.4e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1020 PF06255.8 EME84675.1 - 0.063 12.4 0.1 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) HET PF06985.6 EME84676.1 - 3.4e-33 114.7 0.2 4.1e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M41 PF01434.13 EME84678.1 - 1.6e-67 227.1 3.0 2.6e-67 226.3 2.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME84678.1 - 1.6e-42 144.8 0.0 7.5e-42 142.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ApbA_C PF08546.6 EME84678.1 - 6.2e-27 94.0 0.0 2.1e-26 92.3 0.0 2.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME84678.1 - 4.1e-26 91.2 0.0 7.7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AAA_5 PF07728.9 EME84678.1 - 1.7e-06 27.7 0.0 5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME84678.1 - 3e-05 24.0 0.3 0.0002 21.4 0.1 2.5 2 1 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.8 EME84678.1 - 3.4e-05 22.7 0.1 0.00018 20.3 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EME84678.1 - 3.5e-05 24.5 0.0 0.00012 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME84678.1 - 4.2e-05 22.7 0.0 0.00024 20.2 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME84678.1 - 6.6e-05 22.5 1.1 0.0072 16.0 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EME84678.1 - 0.00047 20.3 0.1 0.041 14.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME84678.1 - 0.0026 17.6 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EME84678.1 - 0.0037 16.7 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EME84678.1 - 0.0055 16.1 1.4 0.09 12.1 0.2 2.5 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME84678.1 - 0.012 14.7 0.0 0.033 13.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 EME84678.1 - 0.018 14.9 0.0 0.064 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EME84678.1 - 0.032 13.3 0.0 2.3 7.2 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 EME84678.1 - 0.067 13.0 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME84678.1 - 0.075 12.1 2.5 0.081 12.0 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EME84678.1 - 0.089 12.7 0.0 0.089 12.7 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_18 PF13238.1 EME84678.1 - 0.11 12.8 0.3 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain FMN_dh PF01070.13 EME84679.1 - 6.9e-114 380.4 0.0 8.3e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EME84679.1 - 1.1e-20 73.1 0.0 2.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EME84679.1 - 1.8e-06 27.1 0.0 3.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EME84679.1 - 0.00021 20.2 0.4 0.0013 17.6 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EME84679.1 - 0.01 15.1 0.4 0.45 9.7 0.0 2.7 2 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 EME84679.1 - 0.01 14.9 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.10 EME84679.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Dus PF01207.12 EME84679.1 - 0.12 11.1 0.2 3 6.5 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EME84679.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Metallophos PF00149.23 EME84680.1 - 2.2e-10 40.2 0.4 8.8e-10 38.3 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ECH PF00378.15 EME84681.1 - 2.1e-21 76.1 0.0 2.5e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EME84681.1 - 0.0045 16.7 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 WD40 PF00400.27 EME84682.1 - 3.1e-41 137.7 16.0 4e-07 29.6 0.1 7.8 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 EME84682.1 - 3.1e-13 49.2 0.2 6e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME84682.1 - 3.5e-09 36.0 0.0 8.4e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EME84682.1 - 0.00045 18.4 0.9 0.29 9.2 0.0 3.6 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME84682.1 - 0.015 14.0 1.8 0.89 8.2 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like Zip PF02535.17 EME84682.1 - 4.4 6.2 8.6 7.3 5.5 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PH_10 PF15411.1 EME84683.1 - 3.5e-42 143.2 0.1 9.7e-42 141.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EME84683.1 - 4.8e-32 111.2 1.0 7.7e-32 110.6 0.7 1.3 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.6 EME84683.1 - 6.2e-32 109.5 0.0 1.6e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EME84683.1 - 1.6e-08 34.1 0.0 3.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EME84683.1 - 0.00053 20.1 0.1 0.0011 19.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PI3K_rbd PF00794.13 EME84683.1 - 0.064 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Methyltransf_23 PF13489.1 EME84684.1 - 1.8e-22 79.7 0.0 2.6e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME84684.1 - 6.7e-19 68.1 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME84684.1 - 2.3e-16 59.7 0.0 3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME84684.1 - 7.4e-16 58.4 0.0 1.3e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME84684.1 - 1.5e-12 48.0 0.0 2.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME84684.1 - 2.9e-08 33.9 0.0 4.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EME84684.1 - 3.5e-07 29.8 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EME84684.1 - 2.1e-06 27.7 0.0 8.8e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME84684.1 - 2.3e-06 26.9 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EME84684.1 - 5.9e-05 21.9 0.0 0.00011 21.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EME84684.1 - 0.00018 20.7 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EME84684.1 - 0.00025 20.2 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EME84684.1 - 0.00036 19.9 0.0 0.00069 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EME84684.1 - 0.14 11.1 0.0 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.1 EME84684.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.8 EME84685.1 - 8.1e-39 133.3 0.0 9.5e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME84685.1 - 2.9e-05 23.0 0.8 0.00022 20.0 0.6 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EME84685.1 - 2.9e-05 23.8 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME84685.1 - 0.0035 17.2 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EME84685.1 - 0.19 10.3 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) CTD_bind PF04818.8 EME84686.1 - 3.7e-21 75.1 0.1 7.1e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. HR1 PF02185.11 EME84686.1 - 0.066 12.9 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Hr1 repeat DMPK_coil PF08826.5 EME84686.1 - 0.62 9.9 6.2 0.37 10.7 0.5 2.9 3 0 0 3 3 3 0 DMPK coiled coil domain like Clathrin_lg_ch PF01086.12 EME84687.1 - 1.4e-72 244.2 1.0 1.6e-72 244.1 0.7 1.0 1 0 0 1 1 1 1 Clathrin light chain EMP24_GP25L PF01105.19 EME84687.1 - 0.019 14.6 0.6 0.026 14.2 0.4 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD rve_3 PF13683.1 EME84687.1 - 0.098 12.1 0.2 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain zf-DHHC PF01529.15 EME84688.1 - 1.3e-27 96.2 1.2 3.3e-27 94.9 0.9 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase DctQ PF04290.7 EME84688.1 - 0.054 13.2 2.3 0.29 10.9 0.2 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF443 PF04276.7 EME84688.1 - 6.2 6.1 6.6 11 5.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF2404 PF10296.4 EME84690.1 - 6e-06 26.3 0.0 4.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF77 PF01910.12 EME84691.1 - 4.3e-32 109.6 0.1 5.2e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 DUF1335 PF07056.6 EME84691.1 - 0.046 13.4 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) ADH_N PF08240.7 EME84692.1 - 8.9e-23 80.1 5.3 1.5e-22 79.4 3.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME84692.1 - 4.4e-21 74.7 0.2 1e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME84692.1 - 1.6e-06 29.0 0.0 5.5e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME84692.1 - 0.0027 16.8 0.5 0.0045 16.1 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EME84692.1 - 0.0039 17.2 0.0 0.007 16.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EME84692.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-NF-X1 PF01422.12 EME84692.1 - 0.14 12.1 2.6 0.33 10.9 1.8 1.6 1 0 0 1 1 1 0 NF-X1 type zinc finger TRAM_LAG1_CLN8 PF03798.11 EME84693.1 - 2.5e-36 125.1 15.8 2.5e-36 125.1 11.0 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EME84693.1 - 2e-15 56.0 0.1 5.4e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Acetyltransf_1 PF00583.19 EME84694.1 - 2.8e-08 33.6 0.0 5.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EME84694.1 - 4.3e-08 33.2 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME84694.1 - 9.3e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME84694.1 - 8.4e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Velvet PF11754.3 EME84694.1 - 0.00012 21.7 0.0 0.00035 20.2 0.0 1.7 1 1 0 1 1 1 1 Velvet factor FR47 PF08445.5 EME84694.1 - 0.00024 20.7 0.0 0.00094 18.8 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EME84694.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EME84694.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME84694.1 - 0.092 12.5 0.0 0.45 10.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB PF00651.26 EME84695.1 - 7.9e-12 45.1 0.6 1.4e-09 37.9 0.0 3.1 2 1 0 3 3 3 1 BTB/POZ domain WD40 PF00400.27 EME84697.1 - 9.6e-46 152.0 12.8 4.7e-09 35.7 0.4 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat PFU PF09070.6 EME84697.1 - 8.9e-39 132.1 0.1 1.6e-38 131.2 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EME84697.1 - 1.5e-21 76.4 0.0 2.3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain Nup160 PF11715.3 EME84697.1 - 0.01 14.0 0.0 0.77 7.8 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MFS_1 PF07690.11 EME84699.1 - 1.4e-40 139.1 65.5 2.3e-39 135.1 44.4 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily WTF PF03303.8 EME84699.1 - 2.5e-05 23.8 7.7 4.9e-05 22.8 5.4 1.5 1 0 0 1 1 1 1 WTF protein Neurensin PF14927.1 EME84699.1 - 0.17 11.2 4.8 4 6.8 0.0 3.8 3 1 1 4 4 4 0 Neurensin Homeobox_KN PF05920.6 EME84700.1 - 1.3e-07 31.2 0.1 5e-07 29.3 0.1 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EME84700.1 - 0.87 9.2 3.2 14 5.4 2.2 2.7 1 1 0 1 1 1 0 Homeobox domain PI-PLC-X PF00388.14 EME84702.1 - 0.00023 20.5 0.0 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Voltage_CLC PF00654.15 EME84703.1 - 1.3e-91 307.2 26.0 2e-91 306.7 18.0 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EME84703.1 - 8.2e-11 41.5 0.0 8.2e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain NmrA PF05368.8 EME84704.1 - 6.6e-12 45.1 0.0 8.9e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME84704.1 - 1.8e-09 37.9 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EME84704.1 - 6.5e-05 23.2 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EME84704.1 - 0.00013 21.4 0.0 0.00025 20.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME84704.1 - 0.00096 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 EME84704.1 - 0.0029 17.5 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EME84704.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EME84704.1 - 0.043 12.5 0.1 0.064 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME84704.1 - 0.099 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein MFS_2 PF13347.1 EME84705.1 - 2e-15 56.1 12.0 5.4e-15 54.7 8.3 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EME84705.1 - 9.1e-14 50.9 20.3 9.1e-14 50.9 14.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3039 PF11238.3 EME84705.1 - 0.023 14.1 0.2 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) PgaD PF13994.1 EME84705.1 - 0.14 11.6 0.0 0.14 11.6 0.0 3.5 3 1 1 4 4 4 0 PgaD-like protein Epimerase PF01370.16 EME84706.1 - 3.3e-23 82.3 0.0 4.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME84706.1 - 6.3e-13 48.0 0.0 7.6e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME84706.1 - 1.9e-08 34.5 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME84706.1 - 1.2e-07 30.8 0.0 0.00096 18.1 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EME84706.1 - 1.4e-07 30.7 0.0 3.9e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EME84706.1 - 1.9e-05 24.6 0.0 0.0015 18.5 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME84706.1 - 0.0038 16.9 0.1 0.19 11.3 0.0 2.3 1 1 1 2 2 2 1 KR domain Ldh_1_N PF00056.18 EME84706.1 - 0.018 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2181 PF10223.4 EME84706.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) UDPG_MGDP_dh_N PF03721.9 EME84706.1 - 0.05 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 EME84706.1 - 0.068 12.0 0.0 0.16 10.8 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2336 PF10098.4 EME84706.1 - 0.081 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) 3HCDH_N PF02737.13 EME84706.1 - 0.086 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F_bP_aldolase PF01116.15 EME84707.1 - 2.4e-79 266.4 0.3 2.7e-79 266.2 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SAP PF02037.22 EME84708.1 - 7.2e-06 25.3 0.2 1.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain RRM_6 PF14259.1 EME84708.1 - 0.041 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rho_N PF07498.7 EME84708.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain BUD22 PF09073.5 EME84708.1 - 4.8 6.1 17.2 4.2 6.3 11.0 1.4 1 1 0 1 1 1 0 BUD22 Pyr_redox_3 PF13738.1 EME84709.1 - 1.2e-29 103.8 0.0 8.7e-29 101.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME84709.1 - 4.9e-13 48.1 0.1 1.8e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME84709.1 - 3.9e-10 39.1 1.0 3.1e-05 23.0 0.0 3.4 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME84709.1 - 2.5e-08 34.0 0.0 1.5e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME84709.1 - 4.5e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME84709.1 - 2.8e-05 23.1 0.0 0.00016 20.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME84709.1 - 0.00014 22.1 0.0 1.1 9.7 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME84709.1 - 0.00018 21.3 0.0 0.005 16.6 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EME84709.1 - 0.00051 20.1 0.1 0.48 10.5 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EME84709.1 - 0.00084 18.3 0.0 0.0016 17.4 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME84709.1 - 0.0019 17.1 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME84709.1 - 0.0079 15.3 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EME84709.1 - 0.085 11.9 0.1 0.22 10.5 0.0 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EME84709.1 - 0.2 10.0 0.4 0.43 8.9 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein DUF3445 PF11927.3 EME84710.1 - 4.5e-70 235.8 0.0 5.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Thr_dehydrat_C PF00585.13 EME84711.1 - 0.018 14.6 0.1 7.1 6.2 0.0 2.4 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase YL1 PF05764.8 EME84712.1 - 1.5e-35 122.9 34.4 2.3e-35 122.3 23.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EME84712.1 - 7.2e-07 28.6 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Daxx PF03344.10 EME84712.1 - 0.028 12.9 25.0 0.036 12.5 17.3 1.1 1 0 0 1 1 1 0 Daxx Family Aa_trans PF01490.13 EME84713.1 - 1.5e-31 109.3 35.4 8.8e-29 100.2 24.5 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.5 EME84713.1 - 1 8.5 2.5 9 5.4 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein 27 F-box PF00646.28 EME84714.1 - 0.00032 20.2 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME84714.1 - 0.0039 16.8 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like BTB PF00651.26 EME84715.1 - 6.1e-11 42.2 0.0 8.4e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain Toxin_13 PF07822.6 EME84715.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein RIO1 PF01163.17 EME84716.1 - 8e-71 237.2 1.1 8e-71 237.2 0.8 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EME84716.1 - 0.0015 18.3 0.0 1.9 8.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family YEATS PF03366.11 EME84718.1 - 2.6e-24 84.7 0.0 3.9e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 YEATS family Tannase PF07519.6 EME84719.1 - 1.8e-99 333.6 0.1 2.1e-99 333.4 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EME84719.1 - 5.2e-08 33.0 0.0 1.4e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME84719.1 - 4.9e-05 23.1 0.0 0.0019 17.9 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME84719.1 - 0.00053 19.2 0.0 0.066 12.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EME84719.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EME84719.1 - 0.067 12.5 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Candida_ALS PF05792.8 EME84719.1 - 0.32 11.1 1.9 0.75 9.9 1.3 1.7 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) Saccharop_dh PF03435.13 EME84720.1 - 1.4e-21 76.9 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EME84720.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.14 EME84721.1 - 6.9e-41 138.0 10.2 7.6e-41 137.8 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EME84721.1 - 0.0013 18.1 1.0 0.029 13.8 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain Elf1 PF05129.8 EME84721.1 - 0.0022 17.6 0.2 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 EME84721.1 - 0.0036 16.9 0.9 0.0053 16.3 0.6 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EME84721.1 - 0.006 16.3 2.9 0.0093 15.7 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EME84721.1 - 0.012 15.3 4.6 0.16 11.7 0.3 2.4 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.11 EME84721.1 - 0.023 14.8 1.5 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 C1 domain zf-H2C2_2 PF13465.1 EME84721.1 - 0.023 14.9 0.4 0.68 10.3 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 EME84721.1 - 0.028 13.6 1.3 3.9 6.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EME84721.1 - 0.033 13.9 0.9 0.054 13.2 0.6 1.4 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Nudix_N_2 PF14803.1 EME84721.1 - 0.062 13.0 2.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal Zn-ribbon_8 PF09723.5 EME84721.1 - 0.066 13.1 1.3 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-FCS PF06467.9 EME84721.1 - 0.092 12.4 1.2 0.94 9.1 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF2175 PF09943.4 EME84721.1 - 0.14 12.2 0.4 8.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Desulfoferrod_N PF06397.7 EME84721.1 - 0.16 11.4 0.9 6.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Sgf11 PF08209.6 EME84721.1 - 0.18 11.1 0.9 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_1 PF00130.17 EME84721.1 - 0.18 11.5 1.4 0.27 10.9 1.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 EME84721.1 - 0.37 10.7 2.6 16 5.4 1.8 2.1 1 1 1 2 2 2 0 FYVE zinc finger YhfH PF14149.1 EME84721.1 - 0.73 9.6 2.8 12 5.7 0.2 2.3 1 1 1 2 2 2 0 YhfH-like protein DUF2688 PF10892.3 EME84721.1 - 0.94 9.1 4.4 2 8.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Ribosomal_L44 PF00935.14 EME84721.1 - 1.7 8.6 9.8 0.51 10.3 3.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 PHF5 PF03660.9 EME84722.1 - 0.11 12.5 0.5 0.32 11.0 0.1 1.9 1 1 0 1 1 1 0 PHF5-like protein zf-RING_2 PF13639.1 EME84722.1 - 6 6.7 6.8 1.7 8.5 0.4 2.7 3 0 0 3 3 3 0 Ring finger domain DAO PF01266.19 EME84723.1 - 2.5e-29 102.3 0.8 4.3e-29 101.5 0.6 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME84723.1 - 0.0049 17.2 3.9 0.0098 16.2 2.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EME84723.1 - 0.005 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 EME84723.1 - 0.006 16.2 0.4 0.01 15.4 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EME84723.1 - 0.0069 15.4 1.9 0.011 14.8 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME84723.1 - 0.0098 14.7 0.3 0.017 14.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME84723.1 - 0.017 14.2 0.9 0.057 12.4 0.5 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 EME84723.1 - 0.022 14.7 1.1 0.051 13.6 0.8 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME84723.1 - 0.028 14.3 2.6 0.053 13.3 1.8 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME84723.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EME84723.1 - 0.078 12.4 0.7 0.15 11.5 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EME84723.1 - 0.19 11.2 0.9 0.34 10.4 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EME84723.1 - 0.4 10.0 3.3 0.63 9.4 2.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Na_Ca_ex PF01699.19 EME84724.1 - 7.5e-28 96.8 16.7 2.8e-16 59.3 2.7 2.8 2 2 0 2 2 2 2 Sodium/calcium exchanger protein E1-E2_ATPase PF00122.15 EME84724.1 - 0.08 11.9 5.8 1.6 7.6 0.6 2.8 2 1 0 2 2 2 0 E1-E2 ATPase Zip PF02535.17 EME84724.1 - 0.17 10.8 6.2 0.98 8.3 4.3 2.2 1 1 0 1 1 1 0 ZIP Zinc transporter Beach PF02138.13 EME84725.1 - 2e-108 361.9 0.2 4.2e-108 360.8 0.2 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EME84725.1 - 1.2e-11 44.4 0.8 2.7e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EME84725.1 - 1.7e-07 30.8 0.1 0.00063 19.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EME84725.1 - 1e-05 25.8 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S8 PF00082.17 EME84726.1 - 3.4e-52 177.3 13.0 4.3e-52 176.9 9.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EME84726.1 - 6.6e-20 71.4 0.5 1.9e-19 70.0 0.3 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 DEAD PF00270.24 EME84727.1 - 6e-30 103.9 0.0 1.3e-29 102.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME84727.1 - 5.3e-14 51.8 0.0 1.5e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME84727.1 - 0.0017 18.2 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EME84727.1 - 0.0017 17.2 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Anillin PF08174.6 EME84728.1 - 2.1e-25 89.3 0.0 7.9e-25 87.5 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EME84728.1 - 5.3e-10 39.4 0.0 1.5e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EME84728.1 - 0.00042 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EME84728.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.20 EME84729.1 - 2e-10 40.8 0.0 2e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84729.1 - 9.4e-06 25.5 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase BTB PF00651.26 EME84732.1 - 2e-14 53.5 0.0 3.7e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_C97 PF05903.9 EME84733.1 - 8.9e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EME84733.1 - 0.009 15.9 3.1 0.052 13.5 0.2 2.3 1 1 1 2 2 2 1 Lecithin retinol acyltransferase DUF778 PF05608.7 EME84733.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) eIF-5a PF01287.15 EME84734.1 - 3.5e-08 33.2 0.0 6.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 2OG-FeII_Oxy PF03171.15 EME84735.1 - 1.1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EME84735.1 - 1.2e-09 38.7 0.0 2.8e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal His_Phos_2 PF00328.17 EME84737.1 - 3.8e-39 135.0 0.0 4.3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 EME84738.1 - 0.00013 21.9 0.6 0.066 13.1 0.2 3.2 2 1 0 2 2 2 1 short chain dehydrogenase CTNNBL PF08216.6 EME84738.1 - 0.16 11.5 0.1 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear Alpha-amylase PF00128.19 EME84739.1 - 3e-23 82.7 1.1 1.6e-21 77.0 0.7 2.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EME84739.1 - 6.4e-15 55.3 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EME84739.1 - 3.2e-07 29.9 0.0 1.4e-06 27.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME84739.1 - 1.8e-06 28.1 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EME84740.1 - 5e-60 203.5 0.0 8.6e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EME84740.1 - 3.5e-26 91.0 0.2 7.4e-26 90.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) TFIIIC_sub6 PF10419.4 EME84740.1 - 0.048 13.1 0.4 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 TFIIIC subunit Mig-14 PF07395.6 EME84741.1 - 0.16 10.9 0.2 0.33 9.9 0.1 1.4 1 1 1 2 2 2 0 Mig-14 CENP-Q PF13094.1 EME84743.1 - 0.014 15.4 3.5 0.11 12.4 0.1 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EME84743.1 - 0.051 13.3 1.4 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding EAP30 PF04157.11 EME84743.1 - 0.076 12.1 0.6 0.72 8.9 0.0 2.4 3 0 0 3 3 3 0 EAP30/Vps36 family DivIVA PF05103.8 EME84743.1 - 0.13 12.2 0.7 0.28 11.2 0.1 1.9 2 1 0 2 2 2 0 DivIVA protein IncA PF04156.9 EME84743.1 - 0.38 10.3 3.1 0.86 9.1 0.1 2.3 2 0 0 2 2 2 0 IncA protein NPP PF08384.5 EME84744.1 - 0.05 13.2 0.2 0.084 12.5 0.1 1.5 1 1 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region DUF1903 PF08991.5 EME84744.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Aha1_N PF09229.6 EME84745.1 - 8.4e-35 119.5 0.8 1.3e-34 118.9 0.5 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EME84745.1 - 1.1e-17 64.3 0.2 2.2e-17 63.2 0.2 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EME84745.1 - 0.00029 21.0 0.3 0.00079 19.6 0.0 1.7 2 0 0 2 2 2 1 Poxvirus A12 protein Drc1-Sld2 PF11719.3 EME84745.1 - 0.017 14.2 1.5 0.022 13.8 1.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Fungal_trans PF04082.13 EME84746.1 - 5.5e-06 25.4 0.1 8.7e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.12 EME84747.1 - 9.4e-81 271.1 0.2 1.1e-80 271.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EME84748.1 - 1.9e-11 43.8 0.5 5.6e-11 42.3 0.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain AAT PF03417.11 EME84749.1 - 3.1e-30 105.2 0.0 4e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EME84749.1 - 0.00047 20.4 0.0 0.0012 19.1 0.0 1.7 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase p450 PF00067.17 EME84750.1 - 6.4e-27 94.1 0.0 7.4e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EME84751.1 - 8.7e-12 44.7 0.0 1.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME84751.1 - 9.1e-11 41.4 0.0 2.3e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EME84751.1 - 0.028 14.2 0.2 0.072 12.8 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cys_Met_Meta_PP PF01053.15 EME84751.1 - 0.059 11.6 0.0 0.11 10.7 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Endonuc-BsobI PF09194.5 EME84754.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI Ecl1 PF12855.2 EME84756.1 - 1.5e-07 30.5 6.8 4.3e-07 29.1 4.7 1.8 1 1 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 EME84756.1 - 0.01 15.3 3.3 0.032 13.7 2.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF329) MAP65_ASE1 PF03999.7 EME84756.1 - 7.3 5.0 7.9 8.1 4.9 5.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Form_Nir_trans PF01226.12 EME84757.1 - 1.3e-12 47.2 5.0 1.5e-12 46.9 3.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter ALAD PF00490.16 EME84758.1 - 3.2e-118 394.3 0.0 3.8e-118 394.0 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase zf-RING_2 PF13639.1 EME84759.1 - 1.2e-06 28.1 1.2 1.2e-06 28.1 0.8 2.2 2 1 0 2 2 1 1 Ring finger domain Prok-RING_1 PF14446.1 EME84759.1 - 0.0038 16.9 1.2 0.0038 16.9 0.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 TFIIF_alpha PF05793.7 EME84759.1 - 0.0056 15.1 14.1 0.0077 14.6 9.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FANCL_C PF11793.3 EME84759.1 - 0.026 14.4 2.1 0.078 12.9 1.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EME84759.1 - 0.035 13.7 3.4 0.06 13.0 1.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-CGNR PF11706.3 EME84759.1 - 0.085 12.3 1.6 0.2 11.1 1.1 1.7 1 0 0 1 1 1 0 CGNR zinc finger HECA PF15353.1 EME84759.1 - 0.19 11.4 4.9 7.3 6.3 0.6 3.3 2 1 0 2 2 2 0 Headcase protein family homologue zf-C3HC4_2 PF13923.1 EME84759.1 - 0.72 9.9 6.4 0.093 12.7 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4544 PF15077.1 EME84759.1 - 1.3 8.4 4.4 2.2 7.6 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Spore_coat_CotO PF14153.1 EME84759.1 - 1.5 8.2 10.5 2.3 7.6 7.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 EME84759.1 - 3.8 5.0 6.3 5 4.6 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.12 EME84759.1 - 7.7 5.2 7.3 11 4.7 5.1 1.1 1 0 0 1 1 1 0 Presenilin HeLo PF14479.1 EME84760.1 - 3e-27 95.7 0.0 4.5e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF1804 PF08822.6 EME84760.1 - 0.088 12.5 0.0 0.6 9.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) ACOX PF01756.14 EME84761.1 - 2.8e-36 124.6 0.2 6.3e-36 123.5 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EME84761.1 - 1.4e-21 77.1 0.1 3.3e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EME84761.1 - 4.8e-12 45.1 2.8 8.6e-12 44.3 0.3 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EME84761.1 - 6.3e-06 26.3 0.2 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain SecA_PP_bind PF01043.15 EME84761.1 - 0.092 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Abhydrolase_6 PF12697.2 EME84762.1 - 3.1e-17 63.2 0.2 3.7e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME84762.1 - 2.8e-09 36.8 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME84762.1 - 4.4e-05 23.2 0.0 7.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.24 EME84763.1 - 4.4e-19 68.9 0.0 7.5e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EME84763.1 - 0.00056 19.5 0.0 0.00096 18.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EME84763.1 - 0.0032 17.6 0.2 0.014 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EME84763.1 - 0.0041 16.7 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME84763.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EME84763.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.4 EME84763.1 - 0.028 13.0 0.0 0.046 12.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EME84763.1 - 0.041 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME84763.1 - 0.065 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EME84763.1 - 0.081 13.7 0.4 0.7 10.7 0.2 2.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME84763.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EME84763.1 - 0.13 12.2 0.7 0.36 10.7 0.0 2.1 3 0 0 3 3 3 0 AAA domain EMP24_GP25L PF01105.19 EME84764.1 - 2.9e-46 157.5 0.2 3.2e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0560 PF10577.4 EME84765.1 - 0.05 11.8 0.0 0.065 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DnaJ PF00226.26 EME84766.1 - 2.5e-21 75.1 2.1 2.5e-21 75.1 1.5 2.5 2 0 0 2 2 2 1 DnaJ domain GvpL_GvpF PF06386.6 EME84766.1 - 0.035 13.7 6.6 0.063 12.8 4.6 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ATP-synt_B PF00430.13 EME84766.1 - 0.18 11.5 10.7 0.44 10.3 7.4 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RNase_H2-Ydr279 PF09468.5 EME84766.1 - 1.2 8.2 7.1 2 7.5 4.9 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF2956 PF11169.3 EME84766.1 - 2.1 8.3 16.7 9.1 6.3 9.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2956) V_ATPase_I PF01496.14 EME84766.1 - 5.9 4.6 10.1 7.8 4.2 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-bind_3 PF12776.2 EME84767.1 - 0.00014 22.4 0.2 0.17 12.5 0.0 3.8 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain RNase_PH PF01138.16 EME84768.1 - 3.5e-23 82.3 0.0 5.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EME84768.1 - 0.00015 21.6 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EME84769.1 - 2.2e-80 269.9 24.8 2.5e-80 269.7 17.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EME84769.1 - 1.5 8.2 22.6 0.13 11.6 12.2 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 EME84769.1 - 2.8 5.7 30.8 3.7 5.3 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family PA26 PF04636.8 EME84769.1 - 4.4 5.8 6.8 5.5 5.5 4.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.12 EME84769.1 - 6.1 5.5 7.5 7.1 5.3 5.2 1.2 1 0 0 1 1 1 0 Presenilin F-box PF00646.28 EME84770.1 - 0.35 10.5 1.5 3.1 7.5 0.0 2.7 3 0 0 3 3 3 0 F-box domain Tom5 PF10642.4 EME84770.1 - 0.44 10.2 3.0 0.42 10.2 0.5 2.1 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase PAZ PF02170.17 EME84772.1 - 0.0085 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Patatin PF01734.17 EME84772.1 - 0.11 12.4 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Patatin-like phospholipase DEAD PF00270.24 EME84773.1 - 5.2e-36 123.6 0.6 8.2e-36 123.0 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME84773.1 - 2.3e-22 78.6 0.1 4.1e-12 45.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EME84773.1 - 1.1e-06 28.5 1.0 6.2e-06 26.1 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PBP-Tp47_a PF14889.1 EME84775.1 - 0.025 13.9 0.1 0.36 10.1 0.0 2.0 1 1 1 2 2 2 0 Penicillin-binding protein Tp47 domain a Spc7 PF08317.6 EME84775.1 - 0.11 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2203 PF09969.4 EME84776.1 - 0.37 11.0 1.7 0.38 10.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 EME84776.1 - 9.6 5.7 11.3 1.4 8.4 1.6 2.4 2 0 0 2 2 2 0 IncA protein Sigma70_ner PF04546.8 EME84778.1 - 0.0034 17.0 5.7 0.0056 16.3 3.9 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region UPF0181 PF03701.9 EME84778.1 - 0.0045 16.2 0.6 0.0095 15.2 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) RXT2_N PF08595.6 EME84778.1 - 0.044 13.5 1.3 0.089 12.5 0.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 EME84778.1 - 0.12 10.2 4.6 0.2 9.5 3.2 1.3 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EME84778.1 - 0.13 11.7 9.4 0.26 10.7 6.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin EBV-NA3 PF05009.7 EME84778.1 - 0.31 10.2 2.2 0.29 10.3 0.1 1.8 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF2457 PF10446.4 EME84778.1 - 0.37 9.4 16.9 0.015 14.0 6.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 EME84778.1 - 0.45 10.7 14.3 1.2 9.4 9.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ANAPC15 PF15243.1 EME84778.1 - 0.92 9.6 8.1 2.4 8.2 5.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF4611 PF15387.1 EME84778.1 - 1.6 8.8 9.0 0.75 9.9 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 EME84778.1 - 2.7 5.9 5.1 5 5.0 3.5 1.4 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EME84778.1 - 6.6 7.1 15.7 25 5.2 10.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_membrane PF00664.18 EME84780.1 - 1e-67 228.4 35.1 5.2e-34 117.9 8.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME84780.1 - 4.4e-67 224.5 0.0 6.7e-33 113.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME84780.1 - 2.2e-12 46.7 0.0 0.0025 17.0 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EME84780.1 - 1.5e-11 44.8 0.0 0.039 13.9 0.0 4.3 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 EME84780.1 - 4.1e-11 43.2 0.9 1.7e-05 24.9 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EME84780.1 - 1.9e-09 36.6 0.5 0.0025 16.4 0.1 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EME84780.1 - 2.8e-09 36.3 0.0 0.002 17.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME84780.1 - 1.7e-08 33.8 0.7 0.0029 17.1 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EME84780.1 - 1.3e-06 29.2 0.0 0.046 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME84780.1 - 6.3e-06 26.3 2.5 0.056 13.5 0.1 3.9 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EME84780.1 - 2.4e-05 24.1 0.3 0.22 11.4 0.0 3.7 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EME84780.1 - 3.7e-05 23.2 0.5 0.35 10.2 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EME84780.1 - 7.1e-05 22.7 0.1 0.29 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EME84780.1 - 0.00013 21.0 0.0 0.14 11.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EME84780.1 - 0.0003 20.8 0.0 0.82 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME84780.1 - 0.00057 19.6 1.9 1.4 8.6 0.1 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.24 EME84780.1 - 0.00059 20.0 1.9 16 5.6 0.1 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EME84780.1 - 0.0017 18.6 0.0 2.6 8.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EME84780.1 - 0.0021 17.9 0.0 7.7 6.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 EME84780.1 - 0.0025 17.9 0.1 3.7 7.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_10 PF12846.2 EME84780.1 - 0.0026 17.2 1.7 0.63 9.4 0.0 3.1 4 0 0 4 4 3 1 AAA-like domain MobB PF03205.9 EME84780.1 - 0.0045 16.7 0.1 3.2 7.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EME84780.1 - 0.0059 16.5 0.0 6.6 6.7 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EME84780.1 - 0.013 15.1 0.3 6.3 6.4 0.1 2.8 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 EME84780.1 - 0.019 14.4 0.5 1.5 8.3 0.0 3.5 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EME84780.1 - 0.021 15.1 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EME84780.1 - 0.029 13.0 0.1 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 EME84780.1 - 0.039 12.8 0.0 7.7 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EME84780.1 - 0.078 11.8 0.2 5.3 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2753 PF10952.3 EME84780.1 - 0.084 12.8 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) DUF87 PF01935.12 EME84780.1 - 0.17 11.6 0.8 9.6 5.9 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 EME84780.1 - 0.21 10.2 0.0 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit SYF2 PF08231.7 EME84781.1 - 3.8e-48 163.4 10.3 3.8e-48 163.4 7.1 2.1 2 0 0 2 2 2 1 SYF2 splicing factor Acetyltransf_2 PF00797.12 EME84782.1 - 1.5e-36 126.2 0.0 2.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase DBC1 PF14443.1 EME84782.1 - 0.092 12.2 0.1 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 DBC1 Transglut_core PF01841.14 EME84782.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF788 PF05620.6 EME84783.1 - 8.7e-47 159.1 0.0 9.9e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_11 PF13414.1 EME84784.1 - 9.3e-39 130.9 25.6 1.8e-12 46.7 0.0 7.0 5 2 2 7 7 7 5 TPR repeat TPR_2 PF07719.12 EME84784.1 - 4.8e-36 119.7 21.4 3.1e-05 23.5 0.0 10.9 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 EME84784.1 - 2e-34 115.7 13.4 9.8e-07 28.1 0.0 10.0 11 0 0 11 11 10 6 Tetratricopeptide repeat Apc3 PF12895.2 EME84784.1 - 1.1e-29 102.4 13.9 3.9e-20 71.7 0.1 5.4 2 1 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EME84784.1 - 1.6e-26 92.0 21.8 2.6e-05 24.0 0.0 8.0 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EME84784.1 - 6.1e-25 87.3 31.7 4.9e-09 36.6 0.0 8.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EME84784.1 - 6.6e-23 78.7 0.9 0.0024 17.5 0.0 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME84784.1 - 2.7e-21 74.1 27.6 0.001 19.4 0.2 11.0 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EME84784.1 - 1.2e-19 70.3 22.8 7.1e-08 32.6 0.7 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EME84784.1 - 2.7e-15 55.1 11.0 0.11 12.7 0.1 8.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EME84784.1 - 8.1e-15 53.3 16.8 0.19 11.6 0.0 9.7 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 EME84784.1 - 3.8e-09 36.4 18.4 0.018 15.4 0.1 8.3 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_3 PF07720.7 EME84784.1 - 5.1e-06 26.1 2.6 0.01 15.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME84784.1 - 0.00036 20.3 21.6 0.0021 17.8 0.5 6.5 6 2 2 8 8 8 2 Tetratricopeptide repeat MIT PF04212.13 EME84784.1 - 0.0016 18.3 4.6 1.6 8.6 0.0 4.9 4 1 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EME84784.1 - 0.0075 16.1 11.4 26 4.9 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 EME84784.1 - 0.025 14.6 1.8 0.8 9.8 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat YfiO PF13525.1 EME84784.1 - 0.054 12.9 3.0 0.17 11.2 0.1 2.8 3 0 0 3 3 3 0 Outer membrane lipoprotein TPR_21 PF09976.4 EME84784.1 - 0.19 11.6 9.2 0.025 14.5 1.2 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat FMN_dh PF01070.13 EME84786.1 - 2.6e-109 365.3 0.0 3.2e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EME84786.1 - 2.1e-18 65.8 0.0 4.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EME84786.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EME84786.1 - 0.0044 16.2 0.0 0.036 13.1 0.0 2.0 1 1 1 2 2 2 1 Nitronate monooxygenase BtpA PF03437.10 EME84786.1 - 0.04 13.1 0.0 0.092 11.9 0.0 1.5 2 0 0 2 2 2 0 BtpA family IMPDH PF00478.20 EME84786.1 - 0.053 12.3 0.0 0.12 11.2 0.0 1.5 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Ammonium_transp PF00909.16 EME84787.1 - 3.3e-113 378.1 21.6 3.8e-113 377.9 15.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Aconitase PF00330.15 EME84788.1 - 1.6e-154 514.8 0.0 6.1e-154 512.9 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME84788.1 - 2.8e-41 140.6 0.0 4.7e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain RNA_Me_trans PF04252.8 EME84789.1 - 1.5e-37 128.9 0.0 1.7e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase CIAPIN1 PF05093.8 EME84792.1 - 2e-35 120.8 4.7 3.7e-35 120.0 3.3 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Sugar_tr PF00083.19 EME84793.1 - 9.9e-45 152.9 7.5 1.1e-44 152.7 5.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME84793.1 - 3.5e-12 45.7 13.8 3.8e-12 45.5 9.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 EME84793.1 - 0.0055 15.9 5.9 0.42 9.7 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1275) Pox_A14 PF05767.7 EME84793.1 - 0.13 12.1 0.3 0.13 12.1 0.2 2.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3278 PF11683.3 EME84793.1 - 1.5 8.8 3.7 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Bax1-I PF01027.15 EME84793.1 - 4.5 6.8 15.3 4.3 6.8 1.1 2.1 1 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Abhydrolase_6 PF12697.2 EME84794.1 - 5e-25 88.7 2.6 6e-25 88.4 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME84794.1 - 6.7e-14 51.8 0.0 9.7e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME84794.1 - 2.2e-07 30.6 0.1 8.8e-07 28.7 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EME84794.1 - 9.9e-05 21.8 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EME84794.1 - 0.00092 19.5 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 EME84794.1 - 0.0036 16.7 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EME84794.1 - 0.0049 16.4 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 EME84794.1 - 0.012 14.9 0.0 0.031 13.5 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EME84794.1 - 0.025 14.1 0.3 0.3 10.6 0.2 2.0 1 1 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EME84794.1 - 0.042 13.1 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) BAAT_C PF08840.6 EME84794.1 - 0.12 12.0 0.0 0.75 9.4 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EME84794.1 - 0.14 11.6 0.0 0.42 10.0 0.0 1.7 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Cu-oxidase_3 PF07732.10 EME84798.1 - 5.1e-37 126.2 4.2 7.7e-37 125.6 0.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME84798.1 - 2.4e-27 95.1 8.8 1.2e-22 79.9 0.2 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EME84798.1 - 1.4e-17 64.0 0.0 1.4e-16 60.7 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase ECH PF00378.15 EME84799.1 - 6.4e-31 107.3 0.0 7.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2099 PF09872.4 EME84799.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) Zn_clus PF00172.13 EME84800.1 - 6.3e-06 25.9 7.2 6.3e-06 25.9 5.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME84800.1 - 0.0011 17.8 0.1 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EME84801.1 - 1.1e-10 41.1 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME84801.1 - 6.1e-07 29.6 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding E1-E2_ATPase PF00122.15 EME84802.1 - 8.2e-19 67.5 0.0 1.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EME84802.1 - 2.7e-18 66.8 0.4 7.2e-18 65.4 0.1 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME84802.1 - 6.3e-14 52.9 0.0 3.5e-13 50.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME84802.1 - 5.9e-11 42.1 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME84802.1 - 0.005 16.4 0.6 0.025 14.1 0.1 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME84802.1 - 0.089 13.0 0.6 0.18 12.0 0.1 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NPDC1 PF06809.6 EME84803.1 - 0.082 11.6 0.1 0.092 11.5 0.1 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) DUF4164 PF13747.1 EME84804.1 - 0.0073 16.4 1.1 0.2 11.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) AAA_27 PF13514.1 EME84804.1 - 0.058 11.0 0.1 0.068 10.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain TarH PF02203.10 EME84804.1 - 0.077 12.8 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue P12 PF12669.2 EME84804.1 - 0.19 11.9 4.8 0.31 11.2 3.3 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family CTP_synth_N PF06418.9 EME84805.1 - 4.4e-116 386.8 0.1 6.1e-116 386.3 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EME84805.1 - 1.3e-50 171.5 0.0 2e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EME84805.1 - 1.2e-05 24.9 0.0 3.5e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EME84805.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Velvet PF11754.3 EME84806.1 - 1e-30 106.8 0.0 1.4e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Velvet factor SET PF00856.23 EME84811.1 - 2.2e-09 37.8 2.0 6.6e-08 33.0 0.0 3.3 3 1 0 3 3 3 1 SET domain AT_hook PF02178.14 EME84811.1 - 0.23 11.2 5.5 0.88 9.4 3.8 2.1 1 0 0 1 1 1 0 AT hook motif Ribosomal_L14 PF00238.14 EME84812.1 - 4e-45 152.5 1.2 4.6e-45 152.3 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.11 EME84813.1 - 5.4e-13 48.3 2.4 1.4e-12 47.1 1.7 1.7 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 EME84813.1 - 0.034 14.0 4.7 0.37 10.7 1.2 2.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EME84813.1 - 0.3 10.9 11.1 0.22 11.3 1.8 2.5 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EME84813.1 - 8.2 6.2 7.4 5.2 6.8 1.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rotamase PF00639.16 EME84814.1 - 1.6e-22 80.0 0.2 3e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EME84814.1 - 9.3e-17 61.3 0.0 1.2e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EME84814.1 - 9.8e-10 38.1 0.9 9.8e-10 38.1 0.6 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EME84814.1 - 3.3e-05 24.5 0.1 5.3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 EME84814.1 - 0.038 13.7 0.2 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 MAM domain zf-RING_2 PF13639.1 EME84816.1 - 5.6e-06 26.0 4.7 5.6e-06 26.0 3.3 5.2 5 2 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 EME84816.1 - 7.7e-06 25.4 3.4 7.7e-06 25.4 2.4 5.3 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 EME84816.1 - 1.6e-05 24.3 1.7 0.00023 20.6 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_2 PF13923.1 EME84816.1 - 0.00022 21.1 2.6 0.00022 21.1 1.8 4.8 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME84816.1 - 0.00038 20.1 3.2 0.00038 20.1 2.2 5.0 5 1 0 5 5 5 2 zinc-RING finger domain SH3_1 PF00018.23 EME84816.1 - 0.0011 18.2 0.0 0.0026 17.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain ZZ PF00569.12 EME84816.1 - 0.0016 17.9 5.6 0.0016 17.9 3.9 3.7 4 1 0 4 4 4 2 Zinc finger, ZZ type zf-RING_6 PF14835.1 EME84816.1 - 0.0077 15.9 0.1 0.0077 15.9 0.1 3.3 3 1 0 3 3 3 1 zf-RING of BARD1-type protein PLA2_B PF01735.13 EME84817.1 - 2.2e-116 388.9 2.9 2.7e-116 388.6 2.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF1900 PF08954.6 EME84818.1 - 3.6e-50 169.0 0.0 1.2e-48 164.0 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EME84818.1 - 6.6e-36 121.7 0.0 1.1e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EME84818.1 - 5e-26 89.5 2.3 1.7e-07 30.8 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EME84818.1 - 0.00019 19.7 0.2 0.16 10.0 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EME84818.1 - 0.073 12.7 0.0 0.24 11.0 0.0 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Alpha_L_fucos PF01120.12 EME84819.1 - 1.3e-76 257.7 1.5 1.7e-76 257.3 1.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase CDC37_N PF03234.9 EME84820.1 - 4.1e-53 180.3 1.5 4.1e-53 180.3 1.0 2.5 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EME84820.1 - 2.3e-39 134.6 1.8 7.5e-39 132.9 0.4 2.4 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EME84820.1 - 1.5e-23 82.4 0.1 1.5e-23 82.4 0.1 2.7 3 0 0 3 3 3 1 Cdc37 C terminal domain Striatin PF08232.7 EME84820.1 - 0.013 15.8 3.5 0.65 10.3 0.6 3.2 3 0 0 3 3 3 0 Striatin family Spectrin PF00435.16 EME84820.1 - 0.11 12.8 4.1 13 6.1 0.1 3.5 3 1 0 3 3 3 0 Spectrin repeat DUF155 PF02582.9 EME84821.1 - 6.5e-56 188.9 3.1 1e-55 188.3 2.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SH3_1 PF00018.23 EME84822.1 - 2.5e-16 58.7 0.1 4.9e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME84822.1 - 1.8e-14 53.0 0.1 3.7e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 EME84822.1 - 9.6e-12 44.8 5.7 1.4e-11 44.3 3.9 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EME84822.1 - 3.7e-10 39.1 0.0 6.5e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain THP2 PF09432.5 EME84822.1 - 0.053 13.3 0.4 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Tho complex subunit THP2 GAS PF13851.1 EME84822.1 - 0.36 9.9 8.2 0.66 9.1 5.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 EME84822.1 - 0.82 9.2 8.0 1.6 8.3 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tmemb_170 PF10190.4 EME84824.1 - 0.00019 21.4 4.4 0.00024 21.1 3.0 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Tetraspannin PF00335.15 EME84824.1 - 0.49 9.6 7.1 0.12 11.5 2.8 1.5 1 1 0 1 1 1 0 Tetraspanin family Bacteriocin_IIc PF10439.4 EME84824.1 - 1.2 9.2 5.4 2.6 8.2 3.7 1.6 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF914 PF06027.7 EME84825.1 - 4e-97 325.0 18.2 5.1e-97 324.7 12.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) HCV_env PF01539.12 EME84825.1 - 0.0035 16.8 6.4 0.0064 15.9 4.4 1.4 1 0 0 1 1 1 1 Hepatitis C virus envelope glycoprotein E1 TPT PF03151.11 EME84825.1 - 0.036 13.7 24.7 0.21 11.2 3.2 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family Tim17 PF02466.14 EME84825.1 - 0.23 11.4 4.2 0.62 10.1 0.7 2.7 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family EamA PF00892.15 EME84825.1 - 1.8 8.6 33.4 0.025 14.6 7.9 2.7 2 1 1 3 3 3 0 EamA-like transporter family Aldolase_II PF00596.16 EME84826.1 - 2.7e-47 160.7 0.3 3.3e-47 160.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain WD40 PF00400.27 EME84827.1 - 2.9e-55 182.2 15.1 1.1e-09 37.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME84827.1 - 7.9e-06 25.7 0.1 0.27 10.9 0.0 3.8 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EME84827.1 - 0.046 12.8 0.1 2.4 7.1 0.0 3.2 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal TFIIE_alpha PF02002.12 EME84828.1 - 2.5e-14 52.6 0.0 2.5e-14 52.6 0.0 2.5 3 1 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EME84828.1 - 0.0019 17.4 0.6 0.006 15.8 0.4 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding zf-FPG_IleRS PF06827.9 EME84828.1 - 0.099 12.2 0.2 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF4207 PF13904.1 EME84828.1 - 5.4 6.3 20.1 10 5.3 14.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PseudoU_synth_1 PF01416.15 EME84829.1 - 3e-20 72.5 0.0 1.5e-08 35.0 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF4441 PF14536.1 EME84829.1 - 0.0035 17.2 0.1 0.0035 17.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4441) Gar1 PF04410.9 EME84829.1 - 8.3 5.8 10.2 0.47 9.8 2.3 2.3 1 1 1 2 2 2 0 Gar1/Naf1 RNA binding region Peroxidase_2 PF01328.12 EME84830.1 - 1.7e-12 46.6 0.0 2.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 DAO PF01266.19 EME84831.1 - 6.7e-54 183.1 0.0 8.2e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME84831.1 - 0.00027 19.9 0.0 0.00078 18.4 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME84831.1 - 0.00043 20.1 0.1 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME84831.1 - 0.00061 19.9 0.1 0.1 12.6 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME84831.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME84831.1 - 0.007 16.2 0.0 0.054 13.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME84831.1 - 0.015 14.1 0.0 0.051 12.4 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EME84831.1 - 0.053 12.6 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EME84831.1 - 0.088 11.6 0.1 0.18 10.6 0.1 1.7 1 1 0 1 1 1 0 FAD binding domain DUF1682 PF07946.9 EME84832.1 - 2.3e-98 328.9 3.2 2.6e-98 328.8 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3007 PF11460.3 EME84832.1 - 1.8 8.6 6.5 22 5.1 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3007) adh_short PF00106.20 EME84833.1 - 2.5e-67 225.9 8.4 3.3e-35 121.4 1.8 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EME84833.1 - 5.2e-35 120.7 2.3 4.4e-19 68.8 0.4 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EME84833.1 - 4.4e-25 87.4 0.0 1e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EME84833.1 - 1.7e-13 50.4 0.0 1.4e-11 44.2 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 EME84833.1 - 0.13 11.9 4.6 0.18 11.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.7 EME84833.1 - 1.1 9.2 5.6 3.7 7.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) WD40 PF00400.27 EME84834.1 - 1.2e-31 107.3 2.1 3.8e-07 29.7 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME84834.1 - 0.00032 20.1 0.0 2 7.9 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_43 PF04616.9 EME84835.1 - 1.7e-11 43.7 5.4 1.1e-09 37.8 1.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 DDOST_48kD PF03345.9 EME84838.1 - 3.7e-158 526.4 0.0 4.2e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Asp PF00026.18 EME84839.1 - 2e-64 217.8 10.0 5.5e-64 216.4 6.9 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME84839.1 - 1.1e-05 25.4 0.0 5.2e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.11 EME84840.1 - 8.1e-21 74.1 28.6 2.8e-15 55.8 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME84840.1 - 9.2e-12 44.2 16.8 1.7e-11 43.3 11.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME84841.1 - 1.1e-34 119.6 39.4 1.1e-34 119.6 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME84841.1 - 6.2e-14 51.4 5.5 6.2e-14 51.4 3.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Myosin_tail_1 PF01576.14 EME84842.1 - 0.00045 18.0 4.4 0.00057 17.7 3.1 1.0 1 0 0 1 1 1 1 Myosin tail OEP PF02321.13 EME84842.1 - 1.1 8.7 7.4 7.5 6.1 5.2 1.9 1 1 1 2 2 2 0 Outer membrane efflux protein DUF605 PF04652.11 EME84844.1 - 2.4 7.4 7.5 3.1 7.1 5.2 1.2 1 0 0 1 1 1 0 Vta1 like Ribonuc_L-PSP PF01042.16 EME84848.1 - 4.5e-40 136.1 0.0 4.9e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Endonuclease_NS PF01223.18 EME84850.1 - 6.4e-60 202.3 0.0 7.9e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Peptidase_C5 PF00770.13 EME84850.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus endoprotease zf-Tim10_DDP PF02953.10 EME84851.1 - 3.6e-22 77.4 0.4 4.2e-22 77.1 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger UPF0253 PF06786.7 EME84851.1 - 0.18 11.9 0.1 0.18 11.9 0.1 1.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0253) Endosulfine PF04667.12 EME84853.1 - 9.5e-25 86.3 0.1 1.7e-24 85.6 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region SCF PF02404.10 EME84854.1 - 0.074 12.2 0.1 0.099 11.8 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor HABP4_PAI-RBP1 PF04774.10 EME84855.1 - 0.042 14.3 7.0 0.11 12.9 4.9 1.8 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family adh_short_C2 PF13561.1 EME84856.1 - 5.2e-26 91.8 0.0 6.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME84856.1 - 1.3e-23 83.7 0.0 1.6e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME84856.1 - 4.7e-08 32.9 0.0 6.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EME84856.1 - 0.0042 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EME84856.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PTSIIA_gutA PF03829.8 EME84856.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component Formyl_trans_N PF00551.14 EME84857.1 - 1.4e-24 86.5 0.0 2.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EME84857.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain AA_permease PF00324.16 EME84859.1 - 2.7e-94 316.2 42.4 3.3e-94 315.9 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME84859.1 - 1.4e-18 66.6 46.9 1.6e-18 66.4 32.1 1.4 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EME84860.1 - 8.1e-27 93.8 46.2 6e-24 84.4 21.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EME84861.1 - 4.8e-25 86.4 0.9 1.6e-06 27.7 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Oxidored_q6 PF01058.17 EME84862.1 - 4.2e-22 78.1 0.0 6.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit GDH_N PF12466.3 EME84862.1 - 0.22 11.5 1.9 0.42 10.6 0.8 1.9 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Sedlin_N PF04628.8 EME84863.1 - 1.2e-20 73.6 0.0 1.5e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region WD40 PF00400.27 EME84865.1 - 2.4e-45 150.8 19.3 1.5e-11 43.6 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EME84865.1 - 0.00021 19.6 6.4 0.58 8.2 0.0 5.1 1 1 4 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EME84865.1 - 0.00038 19.3 0.1 0.015 14.1 0.0 2.8 1 1 1 2 2 2 2 Nup133 N terminal like DUF3312 PF11768.3 EME84865.1 - 0.021 13.0 0.0 0.039 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RicinB_lectin_2 PF14200.1 EME84865.1 - 0.096 13.0 0.4 0.93 9.9 0.0 2.6 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like GRAB PF10375.4 EME84867.1 - 5.9e-09 35.1 0.1 1.1e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 EME84867.1 - 0.0043 16.9 20.2 0.0043 16.9 14.0 3.4 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EME84867.1 - 0.022 12.1 69.7 0.013 12.8 26.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Filament PF00038.16 EME84867.1 - 0.06 12.8 62.0 0.15 11.4 7.3 3.0 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.7 EME84867.1 - 0.073 13.3 17.7 0.067 13.4 1.2 4.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EME84867.1 - 0.12 10.7 47.8 0.069 11.6 20.0 2.1 1 1 1 2 2 2 0 AAA domain WEMBL PF05701.6 EME84867.1 - 0.13 10.7 67.5 0.065 11.6 26.6 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light EzrA PF06160.7 EME84867.1 - 0.38 8.8 49.6 0.15 10.2 11.1 3.1 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EME84867.1 - 0.51 9.4 15.5 0.71 8.9 0.7 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF2353 PF09789.4 EME84867.1 - 0.52 9.5 52.3 0.064 12.5 8.6 3.3 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.1 EME84867.1 - 1.1 9.2 66.1 3.3 7.6 13.4 3.6 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 EME84867.1 - 1.5 8.4 71.6 0.63 9.5 20.1 3.7 1 1 4 5 5 5 0 IncA protein DUF948 PF06103.6 EME84867.1 - 9.1 6.2 15.5 2.4 8.0 2.5 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1680 PF07944.7 EME84869.1 - 1.2e-20 73.3 0.0 6.8e-18 64.2 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) TMF_TATA_bd PF12325.3 EME84870.1 - 0.036 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AMP-binding PF00501.23 EME84873.1 - 1.4e-76 257.5 0.0 1.8e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME84873.1 - 1.4e-11 45.1 0.2 3e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.1 EME84874.1 - 3.4e-27 95.2 0.0 6.7e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME84874.1 - 4.5e-14 52.5 0.0 8.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4106 PF13388.1 EME84875.1 - 0.078 11.9 0.7 0.088 11.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF605 PF04652.11 EME84876.1 - 7.9 5.7 10.4 24 4.2 7.2 1.8 1 0 0 1 1 1 0 Vta1 like PHD PF00628.24 EME84877.1 - 8.1e-11 41.4 8.8 9.3e-11 41.2 6.1 1.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EME84877.1 - 0.0048 17.0 3.6 0.0063 16.6 2.5 1.3 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EME84877.1 - 0.024 14.6 1.7 0.026 14.5 1.2 1.1 1 0 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EME84877.1 - 0.068 13.1 2.2 0.078 12.9 1.5 1.2 1 0 0 1 1 1 0 FANCL C-terminal domain VWC PF00093.13 EME84877.1 - 0.51 10.4 5.4 0.87 9.7 3.7 1.5 1 1 0 1 1 1 0 von Willebrand factor type C domain zf-RING-like PF08746.6 EME84877.1 - 0.72 9.9 3.9 1.4 9.0 2.7 1.5 1 1 0 1 1 1 0 RING-like domain PHD_2 PF13831.1 EME84877.1 - 8.7 5.7 11.4 0.41 10.0 3.6 2.1 2 1 0 2 2 2 0 PHD-finger ING PF12998.2 EME84878.1 - 0.00029 21.0 4.3 0.0005 20.3 0.3 2.9 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding CAF1A PF12253.3 EME84878.1 - 0.0045 17.0 3.8 0.013 15.5 2.7 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Hat1_N PF10394.4 EME84879.1 - 3e-32 111.9 0.0 6.5e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EME84879.1 - 0.033 14.2 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.19 EME84882.1 - 3.1e-115 385.5 4.4 4.1e-58 197.2 1.0 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family DDE_Tnp_1 PF01609.16 EME84884.1 - 0.047 13.2 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain RNA_pol_Rpc34 PF05158.7 EME84884.1 - 0.12 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MCM_N PF14551.1 EME84888.1 - 0.073 13.5 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 MCM N-terminal domain Isochorismatase PF00857.15 EME84889.1 - 3.9e-27 95.2 0.0 5.3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PAP_assoc PF03828.14 EME84890.1 - 1.2e-17 63.6 0.2 2.5e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EME84890.1 - 6e-06 26.4 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EME84890.1 - 0.00087 18.1 0.0 0.033 12.9 0.0 2.1 2 0 0 2 2 2 2 Poly(A) polymerase central domain Rsa3 PF14615.1 EME84890.1 - 0.085 12.1 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Nucleoside_tran PF01733.13 EME84892.1 - 1.2e-33 116.6 11.6 4.3e-26 91.8 1.8 2.4 2 0 0 2 2 2 2 Nucleoside transporter MFS_1 PF07690.11 EME84892.1 - 6.9e-06 25.0 29.9 0.0044 15.7 6.9 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2678 PF10856.3 EME84892.1 - 0.14 11.9 3.9 0.06 13.0 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) VIT1 PF01988.14 EME84893.1 - 3.7e-56 189.9 2.6 4.2e-56 189.7 1.8 1.0 1 0 0 1 1 1 1 VIT family Glyco_hydro_17 PF00332.13 EME84896.1 - 1.5e-09 37.3 2.5 4.7e-09 35.7 1.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 EME84896.1 - 0.0016 17.2 0.3 0.0031 16.3 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 TauD PF02668.11 EME84897.1 - 1.5e-40 139.5 0.1 1.8e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DnaJ PF00226.26 EME84898.1 - 3e-14 52.4 0.9 7.6e-14 51.1 0.7 1.7 1 1 0 1 1 1 1 DnaJ domain AIP3 PF03915.8 EME84899.1 - 7.8e-159 529.1 8.9 7.8e-159 529.1 6.2 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 NPV_P10 PF05531.7 EME84899.1 - 0.56 10.4 6.8 0.65 10.2 0.4 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EME84899.1 - 4.4 7.1 6.1 3.3 7.5 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LsmAD PF06741.8 EME84900.1 - 4.3e-24 84.4 4.6 4.3e-24 84.4 3.2 2.2 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EME84900.1 - 2e-08 34.0 0.0 4.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribonuc_red_lgC PF02867.10 EME84900.1 - 0.1 11.1 0.9 0.18 10.3 0.6 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DUF202 PF02656.10 EME84901.1 - 1.1e-12 48.0 4.3 1.1e-12 48.0 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tctex-1 PF03645.8 EME84902.1 - 3.5e-32 110.2 0.1 4.9e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family His_Phos_2 PF00328.17 EME84904.1 - 2.2e-08 33.8 0.0 1.2e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAD_binding_8 PF13450.1 EME84905.1 - 6.3e-12 45.3 0.1 1.7e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME84905.1 - 3e-09 36.2 0.1 9.9e-08 31.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME84905.1 - 2.6e-06 27.7 0.1 0.1 12.9 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME84905.1 - 4.4e-06 26.0 0.0 0.00037 19.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EME84905.1 - 5.1e-06 26.6 0.1 5.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME84905.1 - 1.1e-05 25.4 0.0 0.001 18.9 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME84905.1 - 1.3e-05 24.2 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME84905.1 - 2.6e-05 22.9 0.2 0.0064 14.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 EME84905.1 - 9.3e-05 22.2 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME84905.1 - 0.00079 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EME84905.1 - 0.0073 15.3 0.0 0.066 12.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EME84905.1 - 0.0087 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 EME84905.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HycI PF01750.13 EME84905.1 - 0.034 13.6 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase maturation protease NAD_binding_7 PF13241.1 EME84905.1 - 0.067 13.4 1.0 0.36 11.0 0.0 2.4 2 1 1 3 3 3 0 Putative NAD(P)-binding Alg14 PF08660.6 EME84906.1 - 1e-48 165.5 0.0 1.8e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like adh_short PF00106.20 EME84907.1 - 1.4e-30 106.4 0.0 2.1e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME84907.1 - 2.5e-25 89.6 0.0 1.7e-23 83.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME84907.1 - 2.2e-15 56.8 0.0 3.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME84907.1 - 4e-06 26.4 0.0 9.5e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Dak1_2 PF13684.1 EME84907.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Polysacc_synt_2 PF02719.10 EME84907.1 - 0.015 14.1 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_17 PF00332.13 EME84908.1 - 1.9e-12 46.8 2.5 6.2e-08 32.0 0.6 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Abhydro_lipase PF04083.11 EME84914.1 - 3.9e-23 80.5 0.1 7.8e-23 79.6 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EME84914.1 - 8.6e-17 61.4 0.4 8.6e-17 61.4 0.3 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 EME84914.1 - 0.00064 19.2 0.2 0.39 10.1 0.0 2.6 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EME84914.1 - 0.0017 18.1 0.0 0.013 15.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pet191_N PF10203.4 EME84915.1 - 4.6e-28 97.0 1.0 5.9e-28 96.7 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 EME84915.1 - 0.056 12.8 0.1 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DSS1_SEM1 PF05160.8 EME84915.1 - 0.12 12.1 0.4 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 DSS1/SEM1 family COBRA PF04833.10 EME84915.1 - 0.13 11.9 0.4 0.18 11.5 0.3 1.2 1 0 0 1 1 1 0 COBRA-like protein F-box PF00646.28 EME84916.1 - 0.14 11.8 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 F-box domain CNH PF00780.17 EME84917.1 - 3.7e-77 259.4 0.0 5.5e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EME84917.1 - 3.4e-33 115.0 1.8 4.2e-33 114.7 0.4 1.8 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EME84917.1 - 1.5e-12 47.6 0.0 1.9e-11 44.0 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EME84917.1 - 7.1e-06 26.1 0.0 3.5e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 PH domain FMO-like PF00743.14 EME84918.1 - 1.2e-17 63.3 1.3 2.3e-16 59.0 0.3 2.2 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME84918.1 - 2.3e-16 60.4 0.0 4.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME84918.1 - 4.7e-08 32.3 0.0 1.8e-05 23.8 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME84918.1 - 3.7e-06 26.8 0.1 2.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME84918.1 - 0.00011 22.0 0.0 0.0047 16.8 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EME84918.1 - 0.0022 16.2 0.1 0.021 13.0 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EME84918.1 - 0.0072 16.1 0.3 0.24 11.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EME84918.1 - 0.041 12.9 0.1 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.10 EME84918.1 - 0.048 13.1 0.0 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 EME84918.1 - 0.11 12.5 0.0 9.3 6.3 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AA_permease PF00324.16 EME84919.1 - 1.4e-108 363.3 29.9 1.7e-108 363.0 20.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME84919.1 - 3.4e-31 108.2 31.3 4.9e-31 107.7 21.7 1.3 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.17 EME84920.1 - 8e-35 120.2 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EME84921.1 - 5.7e-20 71.6 0.0 8.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME84921.1 - 2e-10 40.4 0.1 8.7e-10 38.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME84921.1 - 2.4e-10 40.9 0.1 2.5e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME84921.1 - 1.1e-08 35.4 0.0 6.1e-08 33.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME84921.1 - 2.8e-07 30.9 0.0 8.2e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME84921.1 - 7.6e-06 26.2 0.0 1.9e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME84921.1 - 0.00011 21.6 0.0 0.0007 19.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME84921.1 - 0.0036 17.3 0.0 0.02 14.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME84921.1 - 0.01 14.9 0.0 0.072 12.1 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EME84921.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EME84921.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EME84921.1 - 0.028 13.4 0.0 0.06 12.3 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EME84921.1 - 0.037 13.9 0.1 0.072 13.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase CesT PF05932.8 EME84921.1 - 0.081 12.7 0.0 4.9 7.0 0.0 2.9 3 0 0 3 3 3 0 Tir chaperone protein (CesT) family FmrO PF07091.6 EME84921.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Mito_carr PF00153.22 EME84923.1 - 1.9e-49 165.3 0.6 2.1e-19 69.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Aa_trans PF01490.13 EME84924.1 - 2.6e-98 329.1 15.3 2.6e-98 329.1 10.6 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Dynactin_p22 PF07426.6 EME84925.1 - 0.0023 17.2 0.7 0.0034 16.6 0.5 1.3 1 1 0 1 1 1 1 Dynactin subunit p22 DUF4298 PF14131.1 EME84925.1 - 0.083 12.7 0.2 1.1 9.2 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) DUF4140 PF13600.1 EME84925.1 - 9 6.8 8.9 1 9.8 1.1 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EME84926.1 - 3.8e-295 980.6 0.1 4.3e-295 980.5 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Serine_rich PF08824.5 EME84926.1 - 0.0037 17.0 1.4 0.0038 16.9 0.2 1.6 2 0 0 2 2 2 1 Serine rich protein interaction domain Filament PF00038.16 EME84926.1 - 0.0043 16.5 5.4 0.088 12.2 0.5 2.1 2 0 0 2 2 2 2 Intermediate filament protein Baculo_PEP_C PF04513.7 EME84926.1 - 0.0092 15.8 1.1 3.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus CheZ PF04344.8 EME84926.1 - 0.01 15.5 1.7 0.018 14.6 0.2 2.0 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1515 PF07439.6 EME84926.1 - 0.11 12.3 0.1 0.36 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HWE_HK PF07536.9 EME84926.1 - 0.14 12.6 4.1 0.29 11.5 0.1 2.9 3 0 0 3 3 3 0 HWE histidine kinase Laminin_II PF06009.7 EME84926.1 - 0.19 11.4 1.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 EME84926.1 - 0.24 11.2 2.8 2.2 8.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GvpK PF05121.7 EME84926.1 - 0.44 10.4 2.2 4.3 7.2 0.2 2.6 2 0 0 2 2 2 0 Gas vesicle protein K TBPIP PF07106.8 EME84926.1 - 1.4 8.3 4.5 2.9 7.4 0.5 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pyr_redox_3 PF13738.1 EME84927.1 - 3.2e-16 60.0 0.0 6.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME84927.1 - 6.9e-09 34.4 0.0 7.7e-07 27.6 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME84927.1 - 4.1e-07 29.2 0.0 9.3e-05 21.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME84927.1 - 3.2e-05 23.8 0.0 9.7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EME84927.1 - 0.00044 20.3 0.1 0.83 9.7 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EME84927.1 - 0.0057 15.5 0.1 0.013 14.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EME84927.1 - 0.0072 15.2 0.0 0.073 11.9 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EME84927.1 - 0.0084 15.0 0.6 0.15 10.9 0.4 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME84927.1 - 0.019 14.8 0.4 6.8 6.5 0.0 3.4 2 2 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EME84927.1 - 0.088 11.9 0.1 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 EME84928.1 - 1.9e-23 82.7 43.2 8.6e-23 80.6 23.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME84928.1 - 2e-14 53.0 26.2 8.5e-13 47.6 5.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter NUDIX PF00293.23 EME84929.1 - 1.4e-14 53.9 0.1 2.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EME84929.1 - 7.1e-10 39.1 0.0 2.5e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EME84929.1 - 5.7e-07 28.9 1.6 1.2e-06 27.9 1.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Fungal_trans PF04082.13 EME84934.1 - 2.5e-05 23.3 0.2 3.9e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SIN1 PF05422.7 EME84935.1 - 8.8e-31 106.9 0.1 1.4e-18 66.7 0.2 2.9 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EME84935.1 - 0.024 14.5 0.3 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 GLUT4 regulating protein TUG TBX PF12598.3 EME84935.1 - 3.6 8.0 12.2 0.26 11.6 3.9 2.4 2 0 0 2 2 2 0 T-box transcription factor PRCC PF10253.4 EME84936.1 - 8.2e-32 111.3 1.0 8.2e-32 111.3 0.7 2.7 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Glyco_hydro_88 PF07470.8 EME84937.1 - 2.5e-29 102.4 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF3904 PF13044.1 EME84937.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) TAP42 PF04177.7 EME84937.1 - 0.16 10.8 0.1 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 TAP42-like family Metallothio_Pro PF02069.11 EME84940.1 - 0.029 14.2 2.0 0.035 13.9 1.4 1.1 1 0 0 1 1 1 0 Prokaryotic metallothionein Y_phosphatase3 PF13350.1 EME84941.1 - 4.3e-39 134.3 0.0 8.4e-39 133.4 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EME84941.1 - 1.1e-06 28.6 0.0 3.1e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EME84941.1 - 4.9e-06 26.0 0.0 1.7e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EME84941.1 - 0.00037 19.9 0.0 0.00065 19.1 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EME84941.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EME84941.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Lipase_GDSL PF00657.17 EME84942.1 - 5.8e-11 42.6 1.3 7.3e-11 42.3 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EME84942.1 - 4.5e-08 33.4 2.0 5.6e-08 33.1 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Prenyltrans PF00432.16 EME84944.1 - 3.9e-34 115.8 18.4 1.1e-09 37.7 0.2 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EME84944.1 - 1.2e-23 83.6 0.8 3.8e-15 56.2 0.1 3.3 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EME84944.1 - 4.3e-05 23.4 0.2 0.0008 19.3 0.0 2.7 2 1 1 3 3 3 1 Prenyltransferase-like UPF0444 PF15475.1 EME84945.1 - 1.4 8.9 7.4 13 5.8 5.1 2.0 1 1 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Prenyltransf PF01255.14 EME84947.1 - 9.4e-85 283.2 0.0 1.3e-84 282.8 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4129 PF13559.1 EME84948.1 - 0.0032 17.4 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) DUF1600 PF07667.6 EME84948.1 - 3.7 7.6 9.7 6.2 6.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) HET PF06985.6 EME84950.1 - 5.1e-24 85.0 0.5 6.2e-24 84.7 0.3 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amastin PF07344.6 EME84952.1 - 5.3 6.6 9.9 0.36 10.4 0.2 2.4 1 1 1 2 2 2 0 Amastin surface glycoprotein AA_permease_2 PF13520.1 EME84953.1 - 7.2e-50 169.7 44.9 9.2e-50 169.4 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME84953.1 - 7.6e-23 80.5 36.8 1.1e-22 80.0 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_2 PF03446.10 EME84955.1 - 8.1e-35 120.0 0.1 1.2e-34 119.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME84955.1 - 1.5e-25 89.6 0.0 2.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EME84955.1 - 7.7e-06 24.8 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EME84955.1 - 0.00019 21.7 0.0 0.00041 20.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME84955.1 - 0.009 16.0 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EME84955.1 - 0.026 13.8 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 EME84955.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FBPase PF00316.15 EME84958.1 - 7.8e-122 406.1 0.0 8.9e-122 405.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DnaJ PF00226.26 EME84959.1 - 0.002 17.8 0.3 0.039 13.7 0.2 2.2 1 1 0 1 1 1 1 DnaJ domain DHBP_synthase PF00926.14 EME84960.1 - 4.1e-72 241.4 0.1 2.3e-71 239.0 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-C2H2 PF00096.21 EME84961.1 - 7.5e-20 70.0 26.6 2.9e-05 24.1 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME84961.1 - 1.6e-19 69.0 26.7 3.4e-07 30.2 0.7 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME84961.1 - 2.2e-13 49.4 25.2 0.00031 20.8 2.6 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME84961.1 - 0.00018 21.5 8.9 0.56 10.4 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME84961.1 - 0.0088 16.2 15.0 0.25 11.6 0.1 4.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type C1_4 PF07975.7 EME84961.1 - 0.093 12.7 2.5 1.5 8.8 0.0 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain XPA_N PF01286.13 EME84961.1 - 0.097 12.3 0.3 0.097 12.3 0.2 3.2 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_6 PF13912.1 EME84961.1 - 0.19 11.6 17.3 1.6 8.7 0.8 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EME84961.1 - 6.3 6.8 12.9 21 5.1 0.1 3.9 2 1 2 4 4 4 0 Zinc ribbon domain CAP59_mtransfer PF11735.3 EME84963.1 - 2.2e-74 249.7 0.0 3.9e-74 248.9 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ICMT PF04140.9 EME84965.1 - 1.3e-26 92.6 0.0 2.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EME84965.1 - 1.2e-11 44.6 0.4 1.2e-11 44.6 0.3 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EME84965.1 - 0.00056 19.3 0.6 0.00056 19.3 0.4 2.0 1 1 0 2 2 2 1 NnrU protein DUF1295 PF06966.7 EME84965.1 - 0.00071 18.9 3.1 0.00071 18.9 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PH_10 PF15411.1 EME84966.1 - 1.8e-23 82.9 0.0 3e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EME84966.1 - 6.4e-08 32.4 0.1 4.3e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EME84966.1 - 9.1e-08 31.8 5.4 3.3e-07 30.0 3.1 2.3 2 0 0 2 2 2 1 Ring finger domain VWA PF00092.23 EME84966.1 - 1e-05 25.3 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EME84966.1 - 0.0017 17.9 1.6 0.0032 17.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME84966.1 - 0.0019 17.8 3.8 0.0019 17.8 2.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME84966.1 - 0.0049 16.8 4.6 0.0049 16.8 3.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.24 EME84966.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 PH domain zf-rbx1 PF12678.2 EME84966.1 - 0.02 15.0 1.2 0.043 13.9 0.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME84966.1 - 0.064 12.9 6.0 0.2 11.3 2.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Inhibitor_Mig-6 PF11555.3 EME84968.1 - 0.15 12.4 1.5 2.2 8.7 0.4 2.3 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 SCA7 PF08313.7 EME84969.1 - 4.9e-33 112.5 1.7 4.9e-33 112.5 1.2 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.6 EME84969.1 - 0.00058 19.1 1.9 0.001 18.3 1.3 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) CDC45 PF02724.9 EME84969.1 - 0.5 8.3 10.6 0.65 7.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein HEAT PF02985.17 EME84970.1 - 7.4e-05 22.5 1.2 0.33 11.1 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat BTB PF00651.26 EME84971.1 - 0.0063 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2040 PF09745.4 EME84972.1 - 3.7e-36 123.7 25.2 3.7e-36 123.7 17.4 3.3 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Hexapep_2 PF14602.1 EME84973.1 - 9.8e-14 50.6 6.4 5.5e-11 41.8 1.0 2.6 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EME84973.1 - 1.9e-13 49.2 9.8 6.4e-10 38.0 2.0 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EME84973.1 - 2.1e-06 27.6 0.1 3.7e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.11 EME84974.1 - 1.1e-35 123.0 35.1 1.1e-35 123.0 24.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily HemY_N PF07219.8 EME84974.1 - 0.053 13.0 0.3 0.25 10.8 0.0 2.3 3 0 0 3 3 3 0 HemY protein N-terminus UNC-93 PF05978.11 EME84974.1 - 2.9 7.3 9.6 0.34 10.4 3.4 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Reo_sigmaC PF04582.7 EME84975.1 - 0.024 13.8 3.0 0.039 13.1 2.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Macoilin PF09726.4 EME84975.1 - 0.097 10.9 16.8 0.13 10.5 11.6 1.1 1 0 0 1 1 1 0 Transmembrane protein ACT_5 PF13710.1 EME84975.1 - 1.1 9.1 3.9 1.5 8.6 0.3 2.6 2 1 1 3 3 3 0 ACT domain V_ATPase_I PF01496.14 EME84975.1 - 6 4.5 7.6 9.7 3.9 5.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Complex1_51K PF01512.12 EME84976.1 - 7.9e-46 155.5 0.0 1.3e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EME84976.1 - 1.5e-18 65.6 0.7 3.3e-18 64.5 0.5 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EME84976.1 - 9.5e-10 38.2 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF1100 PF06500.6 EME84977.1 - 8.2e-14 50.9 0.0 1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EME84977.1 - 2.1e-09 37.3 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME84977.1 - 1.5e-08 34.8 0.2 3.3e-08 33.6 0.1 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME84977.1 - 6.3e-06 25.5 0.1 2.7e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EME84977.1 - 1.2e-05 24.8 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EME84977.1 - 0.0026 17.2 0.0 0.021 14.2 0.0 2.1 1 1 0 1 1 1 1 Putative esterase MIT PF04212.13 EME84977.1 - 0.019 14.8 0.9 0.033 14.0 0.6 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain BAAT_C PF08840.6 EME84977.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Usp PF00582.21 EME84978.1 - 2.5e-18 66.6 0.6 6.4e-13 49.0 0.2 2.8 2 0 0 2 2 2 2 Universal stress protein family WD40 PF00400.27 EME84979.1 - 3.8e-28 96.2 6.4 3.1e-10 39.5 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME84979.1 - 0.0011 17.3 0.0 0.43 8.8 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EME84979.1 - 0.012 15.3 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 EME84980.1 - 1.3e-23 83.2 21.5 1.3e-23 83.2 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EME84980.1 - 0.0085 15.8 0.4 0.026 14.3 0.2 1.8 1 0 0 1 1 1 1 MFS_1 like family zf-RING_2 PF13639.1 EME84981.1 - 0.0011 18.7 1.4 0.0018 18.0 0.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME84981.1 - 0.0059 16.2 1.0 0.015 14.9 0.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME84981.1 - 0.012 15.6 0.6 0.023 14.7 0.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME84981.1 - 0.14 12.2 0.9 0.43 10.6 0.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L17 PF01196.14 EME84983.1 - 4.7e-32 110.4 0.2 1.6e-31 108.7 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 Helicase_C_2 PF13307.1 EME84984.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Helicase C-terminal domain Tcf25 PF04910.9 EME84985.1 - 1.8e-75 254.1 0.1 3.1e-75 253.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 SAPS PF04499.10 EME84985.1 - 0.5 8.9 4.2 0.9 8.1 2.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.8 EME84985.1 - 6.7 5.8 18.7 15 4.6 13.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) SCP2 PF02036.12 EME84986.1 - 0.0002 21.6 0.0 0.00044 20.5 0.0 1.6 1 1 0 1 1 1 1 SCP-2 sterol transfer family Epimerase PF01370.16 EME84987.1 - 1.2e-22 80.5 0.0 1.4e-21 77.0 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME84987.1 - 1.4e-18 66.5 0.0 1.8e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME84987.1 - 2e-14 54.0 0.0 3.4e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME84987.1 - 2.1e-14 53.0 0.0 2.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EME84987.1 - 8.2e-06 25.2 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EME84987.1 - 0.00018 21.4 0.2 0.00076 19.4 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EME84987.1 - 0.0021 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EME84987.1 - 0.0085 15.7 0.1 0.021 14.4 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF3368 PF11848.3 EME84987.1 - 0.13 11.8 0.3 0.49 9.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) p47_phox_C PF08944.6 EME84988.1 - 0.75 10.0 0.1 0.75 10.0 0.0 2.6 2 1 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Pyr_redox_2 PF07992.9 EME84989.1 - 3.4e-40 138.0 0.2 4.9e-40 137.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EME84989.1 - 8.4e-32 109.4 0.3 3.8e-31 107.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EME84989.1 - 1.6e-17 63.7 1.9 3.2e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME84989.1 - 1.1e-10 41.9 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME84989.1 - 6.4e-05 22.0 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EME84989.1 - 0.0052 16.3 0.6 0.53 9.8 0.0 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EME84989.1 - 0.047 13.3 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EME84989.1 - 0.079 11.8 0.2 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EME84989.1 - 5.3 5.7 6.7 7.8 5.2 1.6 2.7 3 0 0 3 3 3 0 FAD binding domain Ribonuc_red_lgC PF02867.10 EME84990.1 - 2.1e-216 719.6 0.0 2.9e-216 719.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EME84990.1 - 2e-24 85.2 0.1 4.8e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EME84990.1 - 4.6e-16 59.0 0.4 1.6e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EME84990.1 - 0.056 11.5 0.0 0.089 10.8 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase MBOAT_2 PF13813.1 EME84991.1 - 5.8e-17 61.5 6.1 5.8e-17 61.5 4.2 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Peptidase_M24 PF00557.19 EME84992.1 - 3.3e-47 160.7 0.5 4.4e-47 160.3 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.14 EME84992.1 - 0.0054 15.3 0.0 0.0087 14.6 0.0 1.2 1 0 0 1 1 1 1 Pectinesterase DUF4611 PF15387.1 EME84992.1 - 0.31 11.2 4.6 0.84 9.8 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AMP-binding PF00501.23 EME84993.1 - 1.6e-44 151.9 0.0 2.4e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PNK3P PF08645.6 EME84997.1 - 1.1e-57 193.9 0.1 3.2e-57 192.4 0.0 1.8 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EME84997.1 - 6.6e-26 90.9 0.0 2.5e-25 89.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME84997.1 - 8.8e-06 25.1 0.1 0.0024 17.1 0.0 2.3 1 1 1 2 2 2 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EME84997.1 - 0.0013 18.9 0.8 0.22 11.7 0.0 3.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 EME84997.1 - 0.019 14.0 0.0 0.18 10.8 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin SUR7 PF06687.7 EME84999.1 - 2e-45 154.9 19.3 2.5e-45 154.6 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EME84999.1 - 0.53 10.1 19.1 0.13 12.1 9.9 2.0 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3357 PF11837.3 EME84999.1 - 0.59 10.0 0.1 0.59 10.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2670 PF10875.3 EME84999.1 - 2.4 8.1 5.6 0.49 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2670) Peptidase_C93 PF06035.6 EME85000.1 - 0.12 11.7 1.1 0.22 10.9 0.8 1.4 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Cut8_C PF08559.5 EME85001.1 - 8.4e-45 152.1 0.0 1.3e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EME85001.1 - 1e-15 57.2 2.6 1e-15 57.2 1.8 1.8 2 0 0 2 2 2 1 Cut8 dimerisation domain Nsp1_C PF05064.8 EME85001.1 - 0.051 13.2 1.2 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region Mo25 PF08569.6 EME85001.1 - 0.091 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Mo25-like Cut8_N PF14482.1 EME85001.1 - 0.38 10.7 6.2 0.74 9.8 4.3 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain EamA PF00892.15 EME85002.1 - 3.6e-10 39.9 32.8 5.5e-08 32.8 3.8 3.0 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EME85002.1 - 3.6e-05 23.0 8.2 0.00012 21.2 5.7 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EME85002.1 - 0.00014 21.9 4.7 0.00014 21.9 3.2 3.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EME85002.1 - 1.4 8.5 21.2 0.075 12.6 1.1 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family F-box-like_2 PF13013.1 EME85004.1 - 0.018 14.7 0.1 0.046 13.4 0.0 1.7 2 0 0 2 2 2 0 F-box-like domain Sld5 PF05916.6 EME85006.1 - 1.3e-21 76.8 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.7 EME85007.1 - 2.5e-79 267.0 17.7 1.2e-69 235.1 10.2 3.1 2 1 0 2 2 2 2 DIE2/ALG10 family GST_N_2 PF13409.1 EME85008.1 - 8e-21 73.8 0.0 1.4e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME85008.1 - 1.9e-15 56.5 0.1 9.5e-15 54.2 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME85008.1 - 2.4e-07 30.6 0.0 5.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME85008.1 - 3.8e-05 24.1 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME85008.1 - 0.0004 20.5 0.0 0.0035 17.5 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L3 PF00297.17 EME85009.1 - 8e-37 127.0 4.0 1.3e-35 123.0 2.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Pkinase_Tyr PF07714.12 EME85010.1 - 3.4e-21 75.5 0.0 5.5e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME85010.1 - 9.5e-19 67.5 0.0 1.8e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EME85010.1 - 0.00042 19.3 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Chromo PF00385.19 EME85013.1 - 0.0025 17.4 1.1 0.039 13.6 0.0 2.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SWIB PF02201.13 EME85016.1 - 1.7e-17 62.8 0.0 3.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EME85016.1 - 6.9e-05 22.5 1.1 0.00015 21.4 0.2 1.9 2 0 0 2 2 2 1 DEK C terminal domain zf-Di19 PF05605.7 EME85017.1 - 0.024 14.7 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IncA PF04156.9 EME85017.1 - 0.36 10.3 18.0 2.3 7.8 12.5 2.2 1 1 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EME85017.1 - 9.5 3.9 7.8 22 2.7 5.3 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family KNOX2 PF03791.8 EME85019.1 - 0.087 12.1 0.4 0.16 11.2 0.3 1.5 1 0 0 1 1 1 0 KNOX2 domain SRF-TF PF00319.13 EME85021.1 - 1.5e-05 24.0 0.1 2.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAD_binding_8 PF08022.7 EME85023.1 - 3.6e-08 33.2 0.0 6.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME85023.1 - 0.052 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Cu_bind_like PF02298.12 EME85024.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Plastocyanin-like domain IncA PF04156.9 EME85024.1 - 1.3 8.5 4.2 2.1 7.9 2.9 1.2 1 0 0 1 1 1 0 IncA protein DPBB_1 PF03330.13 EME85025.1 - 1.1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EME85025.1 - 0.008 15.8 0.2 0.008 15.8 0.2 1.2 1 1 0 1 1 1 1 Barwin family DUF3435 PF11917.3 EME85029.1 - 3.1e-64 217.2 12.0 2.3e-41 141.8 8.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) SRF-TF PF00319.13 EME85029.1 - 6.5e-05 22.0 0.1 0.00017 20.7 0.1 1.8 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PV-1 PF06637.6 EME85029.1 - 0.0018 16.9 3.3 0.14 10.7 2.0 2.3 2 0 0 2 2 2 2 PV-1 protein (PLVAP) DUF2414 PF10309.4 EME85030.1 - 3e-18 65.2 0.4 5e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF885 PF05960.6 EME85030.1 - 0.014 14.6 0.3 0.019 14.1 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) HATPase_c_3 PF13589.1 EME85031.1 - 6.9e-11 41.9 0.0 2e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EME85031.1 - 2.6e-09 36.8 0.1 8.5e-08 31.9 0.1 3.0 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EME85031.1 - 0.00031 20.4 0.0 0.0017 18.0 0.0 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.24 EME85033.1 - 3.2e-16 59.7 0.0 6.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME85033.1 - 2.6e-05 24.3 2.3 0.0051 16.9 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EME85033.1 - 0.00027 20.9 0.0 0.00088 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EME85033.1 - 0.00055 19.6 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EME85033.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME85033.1 - 0.018 15.8 1.0 0.13 13.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME85033.1 - 0.019 14.8 0.0 0.072 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EME85033.1 - 0.024 14.2 0.0 0.077 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EME85033.1 - 0.052 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EME85033.1 - 0.06 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME85033.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EME85033.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EME85033.1 - 0.59 9.2 2.2 2.5 7.1 0.1 2.7 2 1 1 3 3 3 0 KaiC AAA PF00004.24 EME85034.1 - 1.9e-16 60.4 0.0 3.4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME85034.1 - 3.7e-06 27.1 0.4 0.0032 17.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EME85034.1 - 0.00021 21.3 0.0 0.00048 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EME85034.1 - 0.00031 20.4 0.1 0.001 18.7 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 EME85034.1 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EME85034.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME85034.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME85034.1 - 0.022 15.5 1.2 0.061 14.1 0.0 2.4 2 2 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EME85034.1 - 0.027 13.5 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EME85034.1 - 0.044 13.3 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EME85034.1 - 0.06 12.8 0.1 1.5 8.2 0.1 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EME85034.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EME85034.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME85034.1 - 0.084 13.1 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EME85034.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EME85034.1 - 0.23 10.5 2.4 1.6 7.7 0.1 2.7 2 1 1 3 3 3 0 KaiC PBP1_TM PF14812.1 EME85034.1 - 0.4 11.0 4.7 0.86 9.9 3.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YedD PF13987.1 EME85037.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 YedD-like protein Acetyltransf_1 PF00583.19 EME85038.1 - 2.4e-13 49.8 0.1 4.2e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME85038.1 - 6e-06 25.9 0.1 1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EME85038.1 - 0.0014 18.7 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME85038.1 - 0.0022 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME85038.1 - 0.0065 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME85038.1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME85038.1 - 0.03 14.1 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME85038.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TMF_DNA_bd PF12329.3 EME85039.1 - 0.037 13.8 0.7 0.037 13.8 0.5 4.1 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4404 PF14357.1 EME85039.1 - 7.1 7.1 12.0 1.1 9.7 2.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Hormone_3 PF00159.13 EME85040.1 - 0.038 13.9 0.8 0.68 9.9 0.1 2.5 2 0 0 2 2 2 0 Pancreatic hormone peptide Pyridoxal_deC PF00282.14 EME85041.1 - 1.4e-109 366.0 0.0 1.9e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EME85041.1 - 0.2 10.5 0.1 0.7 8.7 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II Zn_clus PF00172.13 EME85043.1 - 5.6e-09 35.7 8.7 1.2e-08 34.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME85043.1 - 6.1e-09 34.9 0.0 1.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain EamA PF00892.15 EME85044.1 - 2.9e-12 46.7 31.4 6.1e-09 35.9 4.6 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EME85044.1 - 6.1e-07 28.6 7.6 1.6e-06 27.2 4.1 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EME85044.1 - 2e-06 27.9 2.4 2e-06 27.9 1.7 3.5 3 2 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EME85044.1 - 4.1e-05 23.2 24.5 0.00014 21.5 2.2 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EME85044.1 - 5.7e-05 22.1 7.5 5.7e-05 22.1 5.2 1.4 2 0 0 2 2 2 1 UAA transporter family UPF0546 PF10639.4 EME85044.1 - 7.3 6.4 13.8 3.4 7.5 1.4 3.5 3 1 0 4 4 4 0 Uncharacterised protein family UPF0546 Asp PF00026.18 EME85045.1 - 5.2e-57 193.4 6.3 6.7e-57 193.1 4.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME85045.1 - 1.2e-08 35.1 0.2 3.2e-07 30.4 0.0 2.9 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EME85045.1 - 0.015 14.8 0.0 0.075 12.5 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DUF3176 PF11374.3 EME85046.1 - 5.4e-08 32.6 1.7 9.6e-08 31.8 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SUZ PF12752.2 EME85051.1 - 1.2e-12 48.1 1.7 1.2e-12 48.1 1.2 2.7 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EME85051.1 - 2.4e-09 36.7 0.0 4.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EME85052.1 - 4e-13 48.8 0.4 6.4e-13 48.2 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle SPX PF03105.14 EME85053.1 - 5e-17 62.5 1.5 3.2e-10 40.2 0.1 3.5 1 1 1 2 2 2 2 SPX domain VTC PF09359.5 EME85053.1 - 0.0065 15.5 0.0 2.7 6.9 0.0 3.1 2 1 0 2 2 2 2 VTC domain DUF1619 PF07773.6 EME85053.1 - 0.029 14.2 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) BAR_2 PF10455.4 EME85054.1 - 0.15 10.9 1.5 0.18 10.6 1.0 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking 60KD_IMP PF02096.15 EME85055.1 - 6.9e-10 38.9 1.9 0.00013 21.6 0.1 3.1 3 1 0 3 3 3 2 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EME85056.1 - 1.8e-17 63.2 0.0 3.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EME85056.1 - 3.2e-07 30.5 0.0 2.1e-06 27.8 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME85056.1 - 9.3e-05 22.2 0.0 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 DUF702 PF05142.7 EME85056.1 - 0.79 9.8 9.1 0.15 12.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) PBP_sp32 PF07222.7 EME85056.1 - 0.83 8.7 5.5 1.4 8.0 3.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ADH_N PF08240.7 EME85057.1 - 3.7e-06 26.6 0.0 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME85057.1 - 3.9e-05 23.2 0.0 7.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cyclase PF04199.8 EME85058.1 - 2.7e-13 49.9 1.5 5.8e-13 48.8 1.0 1.4 1 1 0 1 1 1 1 Putative cyclase zf-met PF12874.2 EME85059.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type OTCace PF00185.19 EME85061.1 - 9.9e-40 135.9 0.0 1.6e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EME85061.1 - 2.9e-39 133.9 0.4 4.8e-39 133.2 0.3 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3712 PF12505.3 EME85062.1 - 1.3e-07 31.6 0.0 2e-05 24.6 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EME85062.1 - 4.4e-07 30.2 0.4 0.023 15.0 0.0 4.7 4 0 0 4 4 4 2 Late embryogenesis abundant protein WWbp PF10349.4 EME85064.1 - 1.8e-16 61.0 0.8 1.8e-16 61.0 0.5 1.7 2 0 0 2 2 2 1 WW-domain ligand protein GRAM PF02893.15 EME85064.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 EME85064.1 - 0.0024 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF2580 PF10824.3 EME85064.1 - 0.059 13.7 0.1 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) TPR_12 PF13424.1 EME85066.1 - 6.5e-16 58.0 0.1 9.6e-06 25.4 0.0 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME85066.1 - 2.2e-08 33.4 0.1 0.2 11.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME85066.1 - 2.4e-08 33.2 0.1 0.13 11.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME85066.1 - 8.3e-07 28.5 1.8 0.36 10.5 0.0 4.5 3 2 1 4 4 4 3 TPR repeat TPR_7 PF13176.1 EME85066.1 - 1.2e-06 27.8 0.1 0.41 10.5 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME85066.1 - 0.00021 20.8 0.5 2.6 8.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME85066.1 - 0.00076 19.3 0.4 34 4.5 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME85066.1 - 0.0053 17.3 3.7 0.68 10.6 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EME85066.1 - 0.0069 16.5 1.7 1 9.5 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EME85066.1 - 0.015 15.6 0.2 5 7.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HET PF06985.6 EME85071.1 - 3e-31 108.4 0.2 4.4e-31 107.9 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-synt_C PF00137.16 EME85073.1 - 3e-16 59.0 9.2 4.7e-16 58.4 6.4 1.3 1 0 0 1 1 1 1 ATP synthase subunit C DUF1469 PF07332.6 EME85073.1 - 0.31 10.7 4.5 0.74 9.5 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) Ribosomal_S11 PF00411.14 EME85073.1 - 1.2 9.2 5.4 4.1 7.6 1.0 2.1 1 1 1 2 2 2 0 Ribosomal protein S11 DUF350 PF03994.9 EME85073.1 - 3.3 7.4 7.7 0.87 9.3 2.6 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Lectin_N PF03954.9 EME85075.1 - 0.11 11.9 0.1 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Form_Nir_trans PF01226.12 EME85077.1 - 0.011 14.6 3.2 0.032 13.1 0.1 2.1 1 1 1 2 2 2 0 Formate/nitrite transporter PDR_assoc PF08370.6 EME85077.1 - 0.04 13.4 1.9 0.079 12.4 1.3 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated TPPK_C PF12555.3 EME85077.1 - 0.1 12.3 0.6 0.46 10.2 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal ABC2_membrane_4 PF12730.2 EME85077.1 - 0.18 10.9 9.0 0.03 13.4 1.5 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2189 PF09955.4 EME85077.1 - 0.24 11.3 3.3 0.36 10.7 2.2 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Cation_ATPase_C PF00689.16 EME85077.1 - 0.57 9.6 7.7 6.6 6.2 0.1 2.2 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus MgtC PF02308.11 EME85077.1 - 0.72 9.6 5.6 5.4 6.8 0.3 2.1 2 0 0 2 2 2 0 MgtC family DUF2052 PF09747.4 EME85079.1 - 6.1e-27 94.6 15.7 6.1e-27 94.6 10.9 2.7 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) adh_short PF00106.20 EME85080.1 - 3.6e-16 59.5 0.0 2.2e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EME85080.1 - 0.00055 19.6 0.0 0.0039 16.8 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EME85080.1 - 0.0032 17.2 0.0 0.5 10.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME85080.1 - 0.058 12.8 0.0 6.9 6.0 0.0 2.3 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EME85080.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CD34_antigen PF06365.7 EME85082.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family ETRAMP PF09716.5 EME85082.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2207 PF09972.4 EME85082.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.10 EME85082.1 - 0.18 11.3 0.4 0.32 10.5 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Elf1 PF05129.8 EME85083.1 - 0.037 13.7 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like HisKA PF00512.20 EME85084.1 - 0.15 12.1 4.4 8 6.5 1.0 3.1 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Abhydrolase_3 PF07859.8 EME85087.1 - 2.8e-49 167.5 0.0 3.3e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME85087.1 - 0.0013 17.5 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.13 EME85087.1 - 0.084 12.2 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EME85087.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family K_oxygenase PF13434.1 EME85088.1 - 1e-20 73.9 0.0 5.4e-15 55.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EME85088.1 - 6.6e-14 52.4 0.0 3e-08 33.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME85088.1 - 1.1e-07 32.0 0.0 0.017 15.0 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME85088.1 - 1.1e-05 25.2 1.0 0.094 12.4 0.1 3.3 3 2 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EME85088.1 - 0.0003 19.3 0.0 0.1 11.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 EME85088.1 - 0.0013 17.7 0.2 0.76 8.6 0.0 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME85088.1 - 0.002 17.2 0.0 0.0085 15.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EME85088.1 - 0.0024 17.8 0.1 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME85088.1 - 0.0086 15.0 0.0 0.054 12.3 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EME85088.1 - 0.013 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EME85088.1 - 0.029 14.7 0.0 29 5.1 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME85088.1 - 0.051 12.4 0.1 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DHFR_1 PF00186.14 EME85088.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrofolate reductase Shikimate_DH PF01488.15 EME85088.1 - 0.054 13.5 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pro-kuma_activ PF09286.6 EME85089.1 - 1e-37 129.3 0.4 1.6e-37 128.7 0.3 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME85089.1 - 1e-12 47.8 1.1 1.6e-12 47.2 0.8 1.3 1 0 0 1 1 1 1 Subtilase family KH_1 PF00013.24 EME85092.1 - 1.5e-09 37.3 0.0 1e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EME85092.1 - 1.7e-06 27.5 1.9 0.00031 20.2 0.0 3.3 4 0 0 4 4 4 2 KH domain ALS_ss_C PF10369.4 EME85093.1 - 2.2e-18 65.7 0.0 2.2e-17 62.5 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EME85093.1 - 5.6e-12 44.8 0.1 1.1e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EME85093.1 - 2.4e-09 36.8 0.0 4e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain Sod_Fe_C PF02777.13 EME85094.1 - 1.1e-38 131.3 0.2 2.1e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EME85094.1 - 2.2e-29 101.5 1.8 3.8e-29 100.7 1.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EME85094.1 - 0.069 12.2 5.6 0.81 8.8 0.2 3.5 3 1 1 4 4 4 0 Immunity protein 15 UCR_hinge PF02320.11 EME85095.1 - 1.6e-24 85.5 8.5 2.9e-24 84.7 5.9 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.9 EME85095.1 - 0.011 13.8 11.5 0.011 13.7 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EME85095.1 - 0.047 11.6 21.7 0.05 11.5 15.1 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EME85095.1 - 0.2 10.9 22.8 0.23 10.7 15.8 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EME85095.1 - 0.29 10.1 18.6 0.31 10.0 12.9 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.7 EME85095.1 - 0.99 8.4 25.2 1.5 7.8 17.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4045 PF13254.1 EME85095.1 - 1.2 8.3 5.9 1.4 8.1 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mpp10 PF04006.7 EME85095.1 - 1.6 7.0 22.0 1.9 6.7 15.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Merozoite_SPAM PF07133.6 EME85095.1 - 2 8.2 25.2 2.9 7.7 17.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.10 EME85095.1 - 2.1 6.8 7.2 2.5 6.6 5.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 EME85095.1 - 2.3 6.6 6.0 2.4 6.6 4.1 1.2 1 0 0 1 1 1 0 Raftlin DUF1510 PF07423.6 EME85095.1 - 2.7 7.3 21.3 3.4 6.9 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 EME85095.1 - 3.5 6.7 9.7 3.9 6.5 6.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Tim54 PF11711.3 EME85095.1 - 4 5.9 8.7 4.7 5.7 6.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-T PF15511.1 EME85095.1 - 7.5 5.6 18.4 8.3 5.5 12.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Glyco_hydro_81 PF03639.8 EME85096.1 - 6.5e-171 569.8 4.3 7.4e-171 569.6 3.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Piwi PF02171.12 EME85099.1 - 6.2e-79 265.0 0.0 1.3e-78 264.0 0.0 1.5 2 0 0 2 2 2 1 Piwi domain DUF1785 PF08699.5 EME85099.1 - 3.1e-16 58.4 0.0 8.1e-16 57.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EME85099.1 - 1.2e-14 53.7 0.0 2.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain MMR_HSR1 PF01926.18 EME85100.1 - 7.4e-19 67.8 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EME85100.1 - 4.8e-05 22.5 0.1 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EME85100.1 - 0.00028 20.7 0.0 0.094 12.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.13 EME85100.1 - 0.00041 19.6 0.0 0.011 15.0 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EME85100.1 - 0.0011 18.3 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EME85100.1 - 0.066 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein DUF3380 PF11860.3 EME85100.1 - 0.088 12.8 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) PufQ PF05398.6 EME85101.1 - 0.00081 19.3 0.0 0.0038 17.2 0.0 2.0 2 0 0 2 2 2 1 PufQ cytochrome subunit F-box-like_2 PF13013.1 EME85106.1 - 0.049 13.3 0.3 0.12 12.0 0.2 1.6 1 1 0 1 1 1 0 F-box-like domain SET PF00856.23 EME85107.1 - 0.0016 18.7 0.0 0.0067 16.7 0.0 2.0 1 1 0 1 1 1 1 SET domain Mannosyl_trans2 PF04188.8 EME85108.1 - 1.8e-58 198.5 9.8 2.1e-58 198.3 6.8 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) FAD_binding_4 PF01565.18 EME85110.1 - 7.6e-24 83.7 0.2 1.2e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain YTH PF04146.10 EME85111.1 - 2.7e-33 114.5 0.0 3e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 YT521-B-like domain KH_4 PF13083.1 EME85111.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 KH domain ENTH PF01417.15 EME85112.1 - 3.3e-47 159.4 0.0 4.8e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EME85112.1 - 0.0016 18.4 48.9 0.0016 18.4 33.9 5.4 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) ANTH PF07651.11 EME85112.1 - 0.0031 16.2 0.0 0.0045 15.7 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EME85112.1 - 0.044 13.4 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 VHS domain UIM PF02809.15 EME85112.1 - 0.058 12.9 1.0 0.45 10.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF4264 PF14084.1 EME85112.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Ribosomal_L7Ae PF01248.21 EME85113.1 - 5e-20 70.8 1.0 7.7e-20 70.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pam17 PF08566.5 EME85113.1 - 0.06 13.0 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 zf-TFIIB PF13453.1 EME85114.1 - 0.049 12.8 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger AA_permease PF00324.16 EME85115.1 - 6.5e-112 374.3 41.1 8e-112 374.0 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME85115.1 - 6.8e-27 94.0 45.6 8.3e-27 93.7 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease Isochorismatase PF00857.15 EME85116.1 - 2.4e-43 148.0 0.1 2.7e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_6 PF12697.2 EME85117.1 - 6.8e-23 81.7 0.4 3.1e-22 79.5 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME85117.1 - 2e-09 37.3 0.0 8.9e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME85117.1 - 5e-09 36.0 2.0 1.8e-08 34.2 1.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME85117.1 - 1.8e-07 30.8 0.3 4e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EME85117.1 - 0.015 14.5 0.1 0.039 13.1 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EME85117.1 - 0.035 13.5 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EME85117.1 - 0.041 12.3 0.0 0.063 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 EME85117.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme GPI-anchored PF10342.4 EME85119.1 - 1.9e-06 28.2 2.4 1.9e-06 28.2 1.7 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DotA PF11388.3 EME85121.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Lipase_GDSL_2 PF13472.1 EME85124.1 - 2.1e-21 76.8 0.0 3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME85124.1 - 3.4e-17 63.0 0.0 4.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pectate_lyase_3 PF12708.2 EME85125.1 - 2.3e-83 279.7 20.3 1.2e-65 221.8 5.8 3.0 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EME85125.1 - 6.7e-08 31.8 1.3 0.0074 15.7 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Prok-TraM PF09228.5 EME85126.1 - 0.031 14.4 2.1 0.031 14.4 1.5 1.8 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM AA_permease_2 PF13520.1 EME85127.1 - 1.1e-10 40.6 18.3 1.4e-10 40.3 12.7 1.0 1 0 0 1 1 1 1 Amino acid permease SnoaL_2 PF12680.2 EME85129.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF2358 PF10184.4 EME85129.1 - 0.05 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) dCMP_cyt_deam_1 PF00383.17 EME85130.1 - 3.2e-12 45.9 0.0 5.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EME85130.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Mito_carr PF00153.22 EME85131.1 - 1.3e-66 220.3 3.5 4.2e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1992 PF09350.5 EME85132.1 - 1.9e-26 91.6 0.2 5e-26 90.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) FliG_C PF01706.11 EME85132.1 - 0.083 12.8 0.1 0.083 12.8 0.1 3.0 4 0 0 4 4 4 0 FliG C-terminal domain Chon_Sulph_att PF06566.6 EME85134.1 - 0.46 10.0 3.2 0.61 9.6 2.2 1.3 1 1 0 1 1 1 0 Chondroitin sulphate attachment domain SET PF00856.23 EME85135.1 - 4.8e-14 52.9 0.0 1.3e-13 51.5 0.0 1.8 1 1 0 1 1 1 1 SET domain AMP-binding PF00501.23 EME85136.1 - 2.4e-87 293.0 0.0 2.9e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME85136.1 - 1.3e-15 58.1 0.1 2.9e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EME85137.1 - 3.7e-66 222.9 0.0 4.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME85137.1 - 2.4e-34 118.5 0.0 3.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME85137.1 - 2.7e-05 24.0 0.0 0.016 14.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME85137.1 - 0.0077 15.2 0.0 0.021 13.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EME85137.1 - 0.065 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 E1_dh PF00676.15 EME85139.1 - 2.3e-113 377.8 0.9 2.8e-113 377.5 0.6 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EME85139.1 - 0.018 13.9 0.1 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Mito_carr PF00153.22 EME85140.1 - 2.1e-48 161.9 7.7 4.9e-17 61.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EME85141.1 - 2.5e-52 172.9 18.9 6.4e-09 35.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EME85141.1 - 5.2e-10 38.8 1.2 9.2e-10 38.1 0.8 1.4 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EME85141.1 - 6.5e-07 27.8 10.4 0.034 12.2 0.4 5.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 EME85141.1 - 0.00029 20.4 1.3 0.00052 19.6 0.9 1.5 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EME85141.1 - 0.0014 17.4 0.0 0.033 12.9 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like DUF3275 PF11679.3 EME85141.1 - 0.019 14.5 0.8 0.038 13.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ribosomal_S24e PF01282.14 EME85143.1 - 1.2e-34 117.9 0.0 1.8e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ank_2 PF12796.2 EME85144.1 - 2.9e-45 152.4 4.3 1.3e-18 67.1 0.0 8.4 5 2 1 7 7 7 4 Ankyrin repeats (3 copies) Ank PF00023.25 EME85144.1 - 4.1e-31 105.2 4.7 5.4e-07 29.1 0.0 9.2 12 0 0 12 12 12 4 Ankyrin repeat Ank_4 PF13637.1 EME85144.1 - 1.2e-29 102.1 6.2 1.8e-08 34.6 0.0 11.2 9 3 3 12 12 12 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME85144.1 - 1.7e-29 101.1 5.9 3.6e-05 23.8 0.0 10.6 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME85144.1 - 1e-24 84.1 1.5 0.00013 21.8 0.0 10.2 11 0 0 11 11 11 4 Ankyrin repeat Pro_racemase PF05544.6 EME85145.1 - 9.4e-61 205.4 0.0 1.4e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Proline racemase FGGY_C PF02782.11 EME85146.1 - 2.9e-72 242.4 1.6 4.5e-72 241.8 0.7 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EME85146.1 - 5.1e-64 215.9 0.0 7e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EME85147.1 - 2.2e-57 194.1 6.7 2.6e-57 193.8 4.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Nup96 PF12110.3 EME85148.1 - 6.4e-62 209.2 0.0 9.5e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EME85148.1 - 2.7e-41 140.6 0.0 4.4e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EME85148.1 - 6.4e-41 139.1 387.8 7.9e-16 58.3 30.6 10.9 3 2 5 8 8 8 6 Nucleoporin FG repeat region Glycos_transf_2 PF00535.21 EME85150.1 - 8.8e-23 80.8 0.0 9.2e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME85150.1 - 4.2e-07 30.0 0.2 0.028 14.1 0.0 3.8 2 2 2 4 4 4 3 Glycosyltransferase like family 2 PLAC8 PF04749.12 EME85151.1 - 7.6e-21 74.6 16.3 9.9e-21 74.2 11.3 1.1 1 0 0 1 1 1 1 PLAC8 family Sulfate_transp PF00916.15 EME85152.1 - 1.4e-52 178.4 7.9 2.7e-52 177.5 5.5 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EME85152.1 - 9e-28 95.7 0.6 9e-28 95.7 0.4 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EME85152.1 - 1.9e-13 49.8 0.0 5e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EME85152.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 STAS domain NTP_transferase PF00483.18 EME85156.1 - 5.3e-49 166.7 0.0 1.3e-48 165.4 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EME85156.1 - 2.4e-17 61.5 18.0 3.3e-10 39.0 2.8 4.3 1 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EME85156.1 - 7.1e-11 42.4 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EME85156.1 - 2.5e-07 30.1 1.2 2.5e-07 30.1 0.8 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF2511 PF10709.4 EME85156.1 - 0.077 13.3 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2511) IspD PF01128.14 EME85156.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.14 EME85156.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF3513 PF12026.3 EME85157.1 - 0.12 11.8 0.6 0.78 9.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3513) Sdh_cyt PF01127.17 EME85160.1 - 3.5e-12 46.2 3.7 4.2e-12 45.9 2.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short PF00106.20 EME85161.1 - 2.2e-26 92.7 0.0 3.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME85161.1 - 3.7e-15 56.3 0.0 4.3e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME85161.1 - 1.9e-11 43.9 0.0 2.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME85161.1 - 5.4e-06 26.0 0.0 8.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME85161.1 - 0.12 12.1 0.4 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Acyltransferase PF01553.16 EME85164.1 - 7.5e-31 106.3 0.0 1.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Bot1p PF12298.3 EME85165.1 - 2.3e-50 170.8 4.8 2.3e-50 170.8 3.3 2.1 2 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Methyltransf_3 PF01596.12 EME85166.1 - 8.8e-13 47.7 0.0 1.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EME85166.1 - 1.8e-12 48.0 0.0 2.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME85166.1 - 0.0068 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EME85166.1 - 0.027 13.8 0.0 0.14 11.5 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EME85166.1 - 0.14 12.1 0.1 0.4 10.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Haem_oxygenas_2 PF14518.1 EME85167.1 - 5.5e-12 45.7 0.1 1.3e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Iron-containing redox enzyme LRR_4 PF12799.2 EME85168.1 - 3.6e-45 150.9 49.5 1.2e-09 37.5 0.9 7.2 2 1 7 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME85168.1 - 1.6e-24 85.4 34.1 3.3e-07 29.9 1.8 5.7 2 1 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EME85168.1 - 3.1e-14 50.8 23.1 0.51 10.5 0.0 11.4 11 1 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 EME85168.1 - 1.8e-12 45.9 19.9 0.53 10.5 0.0 10.2 6 2 5 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.1 EME85168.1 - 1.8e-11 43.8 9.8 2e-08 33.9 0.8 3.3 1 1 3 4 4 4 2 Leucine-rich repeat LRR_7 PF13504.1 EME85168.1 - 1.5e-09 36.4 22.4 1.3 9.5 0.0 10.1 11 0 0 11 11 11 4 Leucine rich repeat LRR_3 PF07725.7 EME85168.1 - 3.2 7.6 12.2 9.6 6.1 0.5 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat Zn_clus PF00172.13 EME85169.1 - 1e-10 41.3 11.2 2.1e-10 40.3 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME85169.1 - 2.5e-10 39.6 0.0 6.1e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain SYS1 PF09801.4 EME85169.1 - 0.15 12.0 1.8 0.16 11.9 0.3 1.6 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network SE PF08491.5 EME85170.1 - 2e-104 348.3 0.0 2.5e-104 347.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EME85170.1 - 3.2e-12 46.0 0.4 6e-08 31.9 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME85170.1 - 1.6e-10 40.5 0.0 2.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME85170.1 - 2.7e-05 23.1 1.9 0.002 17.0 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME85170.1 - 7.9e-05 22.6 0.3 0.00019 21.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EME85170.1 - 0.00055 18.8 0.3 0.0035 16.2 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EME85170.1 - 0.00056 19.8 0.2 0.0019 18.1 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME85170.1 - 0.00058 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EME85170.1 - 0.0015 17.5 0.1 0.031 13.1 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EME85170.1 - 0.008 15.3 1.8 0.015 14.4 1.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME85170.1 - 0.011 16.1 0.1 0.031 14.6 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EME85170.1 - 0.019 14.3 0.2 0.049 13.0 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EME85170.1 - 0.021 14.5 0.3 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EME85170.1 - 0.042 13.4 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EME85170.1 - 0.085 11.3 0.1 0.16 10.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EME85170.1 - 0.19 10.3 1.2 3.2 6.2 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase MBOAT PF03062.14 EME85171.1 - 1.2e-19 70.6 22.1 1.8e-19 70.0 15.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EME85171.1 - 4e-05 23.6 2.3 0.00017 21.5 1.6 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family SMK-1 PF04802.10 EME85172.1 - 5.8e-74 247.7 9.1 1.5e-73 246.4 6.3 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 CDC27 PF09507.5 EME85172.1 - 0.22 10.7 3.0 0.37 9.9 2.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HypA PF01155.14 EME85174.1 - 0.24 11.0 4.5 0.28 10.8 2.2 1.8 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Rad60-SLD PF11976.3 EME85175.1 - 1.8e-12 46.7 0.0 3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME85175.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family CAP_N PF01213.14 EME85175.1 - 0.06 12.6 6.4 0.067 12.4 4.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EME85175.1 - 1.7 7.9 14.8 2.7 7.2 10.2 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator Lipase_3 PF01764.20 EME85176.1 - 5.2e-19 68.2 0.0 8.6e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EME85176.1 - 0.00086 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EME85176.1 - 0.0022 17.7 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME85176.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3437 PF11919.3 EME85177.1 - 5.4e-32 109.3 0.0 2.1e-31 107.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EME85177.1 - 8.3e-05 22.3 0.1 2.7 8.3 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat CLASP_N PF12348.3 EME85177.1 - 0.016 14.5 0.0 0.47 9.7 0.0 2.8 3 0 0 3 3 3 0 CLASP N terminal Sld5 PF05916.6 EME85178.1 - 8.4e-11 42.1 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L31e PF01198.14 EME85179.1 - 6.3e-38 128.3 1.1 8.4e-38 127.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e PP2C PF00481.16 EME85180.1 - 5.4e-39 134.1 0.0 8.5e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EME85180.1 - 0.00044 19.9 0.2 0.63 9.7 0.0 3.6 4 0 0 4 4 4 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EME85180.1 - 0.0012 18.2 0.2 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Amidohydro_1 PF01979.15 EME85181.1 - 2.4e-12 47.1 0.0 1.9e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EME85181.1 - 1.5e-11 43.9 0.1 4e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EME85181.1 - 5.6e-06 26.5 0.4 0.0072 16.3 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase Zn_clus PF00172.13 EME85182.1 - 8.2e-09 35.2 10.7 1.8e-08 34.1 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME85182.1 - 1.7e-08 33.6 0.1 2.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EME85183.1 - 5.1e-35 120.8 57.8 1.7e-29 102.6 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EME85183.1 - 0.011 15.5 7.8 0.17 11.7 1.3 3.6 3 1 0 3 3 3 0 MFS_1 like family Coleoptericin PF06286.6 EME85183.1 - 0.31 10.9 1.1 25 4.7 0.0 2.4 2 0 0 2 2 2 0 Coleoptericin DUF3328 PF11807.3 EME85184.1 - 2.2e-26 92.8 0.1 3.4e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HD_5 PF13487.1 EME85185.1 - 0.012 15.6 0.0 0.53 10.3 0.0 3.3 2 0 0 2 2 2 0 HD domain Glyco_hydro_3 PF00933.16 EME85186.1 - 5.8e-46 156.8 0.1 7.3e-46 156.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain adh_short PF00106.20 EME85187.1 - 2.7e-21 76.1 0.0 3.7e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME85187.1 - 4.3e-10 39.7 0.1 5.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME85187.1 - 2e-09 37.3 0.0 2.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME85187.1 - 1.5e-05 24.5 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 4HBT PF03061.17 EME85188.1 - 1.8e-10 40.8 0.1 2.5e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME85188.1 - 0.0049 16.6 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily CN_hydrolase PF00795.17 EME85189.1 - 2e-11 43.5 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PspC PF04024.7 EME85190.1 - 8.3 5.9 8.6 2.2 7.7 1.2 3.0 3 1 0 3 3 3 0 PspC domain Sugar_tr PF00083.19 EME85191.1 - 6e-97 325.0 13.7 3.9e-77 259.7 3.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME85191.1 - 1.4e-24 86.5 9.4 1.4e-24 86.5 6.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EME85191.1 - 0.0084 14.2 1.7 0.017 13.1 1.1 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 EME85192.1 - 5.3e-96 321.5 0.0 6.3e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME85192.1 - 1.8e-12 48.0 0.1 3.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EME85193.1 - 1.4e-29 103.2 1.6 1.7e-29 102.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME85193.1 - 1.6e-20 73.9 0.0 2.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME85193.1 - 2e-09 37.3 1.5 2.8e-08 33.6 1.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME85193.1 - 1.6e-05 24.4 0.1 5.8e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HAD PF12710.2 EME85193.1 - 0.099 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Complex1_LYR_2 PF13233.1 EME85196.1 - 2.7e-21 75.9 0.2 3.2e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME85196.1 - 0.074 12.8 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Fringe PF02434.11 EME85197.1 - 6.5e-09 35.3 0.0 1.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Fringe-like MFS_1 PF07690.11 EME85198.1 - 2e-37 128.7 38.7 2e-37 128.7 26.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME85198.1 - 5e-13 48.4 10.2 5e-13 48.4 7.0 2.4 2 2 0 2 2 2 1 Sugar (and other) transporter PRP38 PF03371.10 EME85200.1 - 1.2e-61 207.3 0.0 1.4e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 PRP38 family F-box PF00646.28 EME85201.1 - 6.3e-07 28.8 0.1 1.8e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME85201.1 - 5.1e-05 22.9 0.4 0.0004 20.0 0.3 2.3 2 0 0 2 2 2 1 F-box-like EBP PF05241.7 EME85202.1 - 5.2e-64 214.8 5.6 6.2e-64 214.5 3.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein RELT PF12606.3 EME85202.1 - 0.11 11.6 0.3 0.29 10.2 0.2 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 AAA_12 PF13087.1 EME85203.1 - 8.3e-39 133.0 0.0 1.5e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME85203.1 - 2.5e-26 92.6 0.0 1e-25 90.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME85203.1 - 3.6e-10 39.4 0.0 9.4e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EME85203.1 - 7.2e-08 32.2 0.0 1.3e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EME85203.1 - 4.8e-06 26.2 0.0 0.026 14.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EME85203.1 - 0.0039 17.0 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EME85203.1 - 0.0057 15.9 0.0 0.019 14.1 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EME85203.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EME85203.1 - 0.026 13.5 0.0 0.18 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ORF6C PF10552.4 EME85203.1 - 0.046 13.4 0.5 0.094 12.4 0.4 1.5 1 0 0 1 1 1 0 ORF6C domain SpoU_sub_bind PF08032.7 EME85203.1 - 0.047 13.8 0.3 0.11 12.6 0.2 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DEAD PF00270.24 EME85203.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EME85203.1 - 0.088 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME85203.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein WD40 PF00400.27 EME85204.1 - 2.1e-18 65.4 6.3 2.8e-05 23.8 0.0 7.9 8 0 0 8 8 8 3 WD domain, G-beta repeat Nop14 PF04147.7 EME85204.1 - 0.0032 15.4 22.3 0.0042 15.1 15.5 1.1 1 0 0 1 1 1 1 Nop14-like family DUF572 PF04502.8 EME85204.1 - 0.23 10.6 3.8 0.34 10.0 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nucleoplasmin PF03066.10 EME85204.1 - 0.46 9.9 0.0 0.46 9.9 0.0 3.3 2 1 0 2 2 2 0 Nucleoplasmin Daxx PF03344.10 EME85204.1 - 1.4 7.2 23.7 2.5 6.4 16.4 1.3 1 0 0 1 1 1 0 Daxx Family Aldo_ket_red PF00248.16 EME85205.1 - 1.8e-16 59.7 0.0 2.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MIP PF00230.15 EME85206.1 - 6e-46 156.7 17.1 6.9e-46 156.5 11.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein Ctr PF04145.10 EME85206.1 - 0.32 11.0 5.1 2.2 8.3 0.0 3.3 2 1 1 3 3 3 0 Ctr copper transporter family Amidase PF01425.16 EME85207.1 - 2.6e-102 342.9 0.0 3.1e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 EME85208.1 - 7.4e-08 32.0 0.2 1.2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME85208.1 - 9.4e-05 22.1 0.0 0.0003 20.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME85208.1 - 0.0085 16.9 0.8 0.025 15.4 0.2 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 EME85208.1 - 0.043 13.7 6.3 0.2 11.5 4.4 1.9 1 1 1 2 2 2 0 short chain dehydrogenase CMD PF02627.15 EME85209.1 - 0.0092 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.11 EME85210.1 - 2.1e-22 79.3 72.9 8.9e-20 70.6 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 EME85211.1 - 1e-181 603.9 0.0 1.9e-98 329.6 0.1 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EME85211.1 - 1e-73 247.8 1.3 4.8e-36 124.1 0.1 3.3 3 0 0 3 3 3 3 Condensation domain AMP-binding_C PF13193.1 EME85211.1 - 1.7e-18 67.3 0.3 3.8e-10 40.5 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EME85211.1 - 4.3e-10 39.7 0.3 2.5e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Alpha-amylase PF00128.19 EME85212.1 - 8.9e-81 271.7 0.0 1.2e-80 271.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EME85212.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Abhydrolase_6 PF12697.2 EME85213.1 - 8.4e-15 55.2 0.0 1.1e-14 54.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME85213.1 - 1.1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EME85213.1 - 0.00022 20.7 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase PE-PPE PF08237.6 EME85213.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF676 PF05057.9 EME85213.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.7 EME85213.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EME85213.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EME85214.1 - 3.2e-08 33.7 0.2 2.4e-07 30.8 0.1 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EME85214.1 - 0.0041 16.7 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 EME85214.1 - 0.005 16.6 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EME85215.1 - 7.6e-28 97.2 0.0 8.8e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME85215.1 - 4.2e-06 26.5 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EME85215.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BSD PF03909.12 EME85216.1 - 5.4e-20 70.9 3.7 1.3e-12 47.2 0.0 2.9 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EME85216.1 - 3.3e-16 58.7 0.2 1e-15 57.1 0.1 1.9 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Mnd1 PF03962.10 EME85216.1 - 5.6 6.5 9.5 0.69 9.5 0.2 3.0 3 1 1 4 4 4 0 Mnd1 family His_Phos_2 PF00328.17 EME85217.1 - 2.4e-24 86.3 0.0 2.9e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EME85217.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) BRCT PF00533.21 EME85218.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S16 PF00886.14 EME85219.1 - 6.2e-22 77.0 0.1 9e-22 76.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 F-box PF00646.28 EME85220.1 - 3.5e-08 32.8 0.2 1.4e-07 31.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME85220.1 - 2.2e-07 30.4 0.0 6.8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like FixO PF02433.10 EME85220.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DLIC PF05783.6 EME85221.1 - 3.4e-09 35.9 21.8 0.007 15.0 0.0 5.2 4 1 1 5 5 5 5 Dynein light intermediate chain (DLIC) tRNA_lig_CPD PF08302.6 EME85221.1 - 0.073 12.2 0.3 0.37 9.9 0.3 1.9 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain WD40 PF00400.27 EME85223.1 - 2.2e-13 49.5 1.0 0.00011 21.9 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Septin PF00735.13 EME85224.1 - 3.2e-105 351.2 0.1 6e-105 350.2 0.0 1.5 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EME85224.1 - 1.8e-05 24.6 1.3 0.14 11.9 0.0 3.0 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EME85224.1 - 0.00017 21.4 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EME85224.1 - 0.0011 19.7 1.8 0.054 14.3 0.0 2.9 2 2 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME85224.1 - 0.0052 15.9 0.1 0.018 14.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EME85224.1 - 0.011 16.2 0.0 0.045 14.2 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 EME85224.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.1 EME85224.1 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1250 PF06855.7 EME85224.1 - 0.096 12.2 0.3 0.2 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) AAA_22 PF13401.1 EME85224.1 - 0.12 12.4 0.4 0.41 10.7 0.0 2.1 2 2 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EME85224.1 - 6.4 4.4 5.7 9.5 3.9 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zn_clus PF00172.13 EME85225.1 - 7.9e-08 32.0 8.0 1.5e-07 31.1 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1751 PF08551.5 EME85227.1 - 0.0028 17.9 1.6 0.0028 17.9 1.1 1.8 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) BTB PF00651.26 EME85228.1 - 6.3e-09 35.8 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pyr_redox_3 PF13738.1 EME85229.1 - 1.4e-42 146.0 0.0 1.9e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME85229.1 - 0.00023 21.1 0.0 0.0026 17.7 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME85229.1 - 0.0078 16.0 0.0 0.83 9.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EME85229.1 - 0.0083 16.2 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EME85229.1 - 0.01 14.7 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EME85229.1 - 0.018 14.1 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Fe-ADH PF00465.14 EME85229.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HET PF06985.6 EME85231.1 - 3.6e-32 111.4 0.0 4.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MRP-L46 PF11788.3 EME85234.1 - 2.1e-28 99.1 0.0 4.8e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EME85234.1 - 0.037 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain AAA PF00004.24 EME85239.1 - 4.7e-16 59.1 0.0 8.1e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME85239.1 - 0.00024 20.2 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME85239.1 - 0.00075 19.6 0.5 0.034 14.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EME85239.1 - 0.0011 19.7 0.0 0.0052 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME85239.1 - 0.016 15.1 0.1 0.083 12.8 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EME85239.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EME85239.1 - 0.098 11.7 0.6 0.48 9.5 0.2 2.0 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 EME85239.1 - 0.099 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EME85239.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EME85239.1 - 0.14 11.6 0.2 15 4.9 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Exo_endo_phos PF03372.18 EME85240.1 - 1.7e-16 60.9 0.1 2.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ofd1_CTDD PF10637.4 EME85241.1 - 5.9e-88 294.4 0.0 9.6e-80 267.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EME85241.1 - 9.2e-16 58.1 0.1 2.6e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EME85241.1 - 0.012 15.2 0.1 0.041 13.5 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EME85242.1 - 0.00052 19.2 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MARVEL PF01284.18 EME85243.1 - 0.0012 18.6 15.8 0.011 15.5 10.7 2.0 1 1 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.1 EME85243.1 - 0.11 12.5 4.9 7 6.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF2763 PF10961.3 EME85243.1 - 0.14 12.5 0.3 14 6.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) RabGAP-TBC PF00566.13 EME85244.1 - 2.4e-47 161.1 0.0 3.5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EME85244.1 - 6e-05 22.5 4.7 0.065 13.1 0.4 3.7 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 EME85244.1 - 0.00092 19.3 0.4 0.022 14.8 0.3 2.7 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EME85244.1 - 0.0043 16.2 1.3 2.1 7.8 0.5 3.2 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EME85244.1 - 0.092 12.1 1.9 0.31 10.4 0.5 2.5 2 0 0 2 2 2 0 EF hand Ras PF00071.17 EME85246.1 - 3.6e-55 185.7 0.0 4.5e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME85246.1 - 2.1e-18 66.9 0.0 3.2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME85246.1 - 5.1e-12 45.3 0.0 6e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME85246.1 - 3.6e-07 30.1 0.0 5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME85246.1 - 4.1e-07 29.6 0.0 1.4e-05 24.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME85246.1 - 1.8e-06 27.2 0.0 2.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EME85246.1 - 0.00087 19.4 0.0 0.0016 18.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME85246.1 - 0.0012 18.0 0.1 0.0024 17.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EME85246.1 - 0.0033 17.1 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EME85246.1 - 0.0054 16.3 0.2 0.0095 15.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EME85246.1 - 0.0057 16.2 0.3 0.17 11.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EME85246.1 - 0.007 16.0 0.1 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EME85246.1 - 0.0083 15.5 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EME85246.1 - 0.0095 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EME85246.1 - 0.012 15.0 0.1 0.097 12.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EME85246.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain Septin PF00735.13 EME85246.1 - 0.015 14.2 0.1 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Septin cobW PF02492.14 EME85246.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EME85246.1 - 0.026 14.2 0.1 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EME85246.1 - 0.039 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EME85246.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain EXOSC1 PF10447.4 EME85247.1 - 4.3e-23 81.0 0.3 5.9e-23 80.6 0.2 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EME85247.1 - 1.6e-07 30.4 0.0 2.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Utp11 PF03998.8 EME85248.1 - 1e-54 185.9 12.7 1.2e-54 185.7 8.8 1.1 1 0 0 1 1 1 1 Utp11 protein CENP-F_leu_zip PF10473.4 EME85248.1 - 0.48 10.2 10.1 0.55 10.0 0.7 2.8 3 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 adh_short PF00106.20 EME85249.1 - 3.6e-25 88.8 0.2 4.8e-25 88.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME85249.1 - 4.6e-14 52.4 0.1 6.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME85249.1 - 1.2e-11 44.9 0.0 1.5e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EME85249.1 - 0.0056 15.7 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase HI0933_like PF03486.9 EME85249.1 - 0.0086 14.5 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Epimerase PF01370.16 EME85249.1 - 0.023 14.1 0.1 0.096 12.0 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.1 EME85249.1 - 0.038 14.0 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3Beta_HSD PF01073.14 EME85249.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TFIID-31kDa PF02291.10 EME85250.1 - 3e-36 124.0 0.0 8.2e-36 122.6 0.0 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PI3_PI4_kinase PF00454.22 EME85251.1 - 1.7e-30 106.2 0.0 2.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EME85251.1 - 6.4e-18 64.2 0.0 1.4e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Radical_SAM PF04055.16 EME85251.1 - 0.14 12.3 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Radical SAM superfamily SAPS PF04499.10 EME85253.1 - 8.4e-189 628.1 0.1 7.6e-188 624.9 0.0 2.2 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein AAA_21 PF13304.1 EME85254.1 - 4e-07 30.3 0.0 6.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EME85254.1 - 0.00011 21.4 23.1 0.00018 20.7 16.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.19 EME85254.1 - 0.011 14.9 19.5 0.021 13.9 13.5 1.4 1 0 0 1 1 1 0 ABC-2 type transporter ABC_tran PF00005.22 EME85254.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ABC2_membrane_2 PF12679.2 EME85254.1 - 0.31 9.8 11.9 0.52 9.1 8.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_membrane PF00664.18 EME85255.1 - 3.4e-42 144.7 12.9 4.6e-42 144.3 8.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EME85255.1 - 1.9e-34 118.8 0.5 8.7e-34 116.7 0.0 2.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.14 EME85255.1 - 0.00021 20.5 0.0 0.00034 19.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EME85255.1 - 0.00039 19.8 0.1 0.0015 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME85255.1 - 0.0018 18.3 0.4 0.016 15.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME85255.1 - 0.005 16.8 0.4 0.035 14.0 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EME85255.1 - 0.0053 16.7 0.0 0.83 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME85255.1 - 0.015 14.7 0.0 0.053 13.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EME85255.1 - 0.018 15.8 0.2 0.063 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EME85255.1 - 0.019 15.1 0.1 0.2 11.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EME85255.1 - 0.023 14.1 2.1 0.24 10.8 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase SbcCD_C PF13558.1 EME85255.1 - 0.032 14.1 0.5 0.19 11.6 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit APOBEC_C PF05240.9 EME85255.1 - 0.17 11.2 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Aldo_ket_red PF00248.16 EME85256.1 - 1.4e-54 184.8 0.0 1.7e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Psb28 PF03912.9 EME85256.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Psb28 protein DUF3328 PF11807.3 EME85258.1 - 9e-18 64.7 0.1 1.8e-16 60.4 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EME85259.1 - 1.8e-36 125.8 6.0 2.6e-36 125.3 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) OxoDH_E1alpha_N PF12573.3 EME85260.1 - 0.00014 21.2 6.5 13 5.4 0.3 5.0 5 0 0 5 5 5 5 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF3237 PF11578.3 EME85261.1 - 4.6e-30 103.8 0.0 1.2e-29 102.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Vps16_N PF04841.8 EME85262.1 - 3.1e-93 312.5 0.0 4e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EME85262.1 - 2.5e-83 279.6 1.4 4e-83 279.0 1.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Coatomer_WDAD PF04053.9 EME85262.1 - 0.018 13.8 0.1 4.9 5.8 0.1 3.5 4 0 0 4 4 4 0 Coatomer WD associated region DUF3279 PF11682.3 EME85263.1 - 0.056 13.0 0.3 0.056 13.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) YfdX PF10938.3 EME85264.1 - 0.074 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 YfdX protein Cation_efflux PF01545.16 EME85266.1 - 3.1e-34 118.3 2.4 4.3e-34 117.8 1.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2460 PF09343.5 EME85266.1 - 0.043 13.1 0.1 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) FTR1 PF03239.9 EME85266.1 - 0.059 12.3 0.0 0.059 12.3 0.0 2.0 3 0 0 3 3 3 0 Iron permease FTR1 family ADH_N PF08240.7 EME85267.1 - 6.7e-26 90.1 1.0 1.3e-25 89.2 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME85267.1 - 1.2e-21 76.6 0.1 1.7e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME85267.1 - 9.5e-06 26.5 0.0 1.8e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NTP_transf_3 PF12804.2 EME85267.1 - 0.11 12.5 0.1 0.95 9.5 0.0 2.1 2 0 0 2 2 2 0 MobA-like NTP transferase domain Shikimate_DH PF01488.15 EME85267.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EME85267.1 - 0.18 12.2 3.9 2.3 8.6 1.5 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EME85267.1 - 0.3 10.2 1.3 0.59 9.2 0.1 1.9 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EME85267.1 - 1.5 8.6 4.3 8.8 6.1 1.5 2.3 1 1 1 2 2 2 0 ThiF family PhoD PF09423.5 EME85270.1 - 6.8e-154 512.7 2.6 7.9e-154 512.5 1.8 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase GMC_oxred_C PF05199.8 EME85271.1 - 4.3e-19 69.2 0.0 7.8e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EME85271.1 - 8.3e-10 38.2 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase CFEM PF05730.6 EME85272.1 - 1.5e-13 50.3 8.1 2.7e-13 49.5 5.6 1.4 1 0 0 1 1 1 1 CFEM domain Dynamin_N PF00350.18 EME85276.1 - 0.011 15.5 0.1 0.046 13.5 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Tn7_Tnp_TnsA_N PF08722.6 EME85276.1 - 0.039 13.9 0.6 0.11 12.5 0.4 1.7 1 0 0 1 1 1 0 TnsA endonuclease N terminal Ras PF00071.17 EME85277.1 - 1.4e-49 167.6 0.1 1.4e-39 135.0 0.1 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EME85277.1 - 5.2e-16 59.2 0.1 3.7e-15 56.4 0.1 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME85277.1 - 1.7e-11 43.6 0.0 5.6e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME85277.1 - 9.5e-09 34.9 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME85277.1 - 1.2e-06 27.8 0.3 5.4e-06 25.7 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME85277.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Lysine_decarbox PF03641.9 EME85278.1 - 8e-32 109.8 0.4 1.3e-31 109.1 0.3 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Phosphodiest PF01663.17 EME85279.1 - 7.4e-15 55.1 0.6 7.4e-15 55.1 0.4 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME85279.1 - 1.5e-06 27.6 0.0 4.3e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EME85279.1 - 4.4e-06 26.2 1.5 7.3e-06 25.5 1.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Gly-zipper_Omp PF13488.1 EME85279.1 - 0.02 14.4 5.9 0.085 12.5 4.1 2.1 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EME85279.1 - 0.15 11.6 3.1 0.42 10.2 2.2 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EME85279.1 - 3.2 7.3 13.1 0.15 11.5 4.8 2.0 2 0 0 2 2 2 0 YMGG-like Gly-zipper Phage_holin_2 PF04550.7 EME85279.1 - 4.6 7.3 9.8 0.29 11.2 2.0 2.4 2 0 0 2 2 2 0 Phage holin family 2 RCR PF12273.3 EME85280.1 - 0.0048 17.4 0.1 0.01 16.4 0.0 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Sarcoglycan_2 PF05510.8 EME85280.1 - 0.0088 14.3 0.1 0.01 14.1 0.0 1.1 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon DUF3609 PF12259.3 EME85280.1 - 0.027 13.1 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) CSF-1 PF05337.6 EME85280.1 - 0.036 13.4 0.8 0.056 12.7 0.3 1.4 1 1 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) DUF1049 PF06305.6 EME85280.1 - 0.046 13.2 0.5 0.069 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) PgaD PF13994.1 EME85280.1 - 0.076 12.4 0.3 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 PgaD-like protein MLANA PF14991.1 EME85280.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF4381 PF14316.1 EME85280.1 - 0.16 12.0 0.3 0.22 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TarH PF02203.10 EME85280.1 - 0.26 11.0 1.3 0.35 10.6 0.9 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Tad PF13400.1 EME85280.1 - 0.57 10.2 5.1 1.1 9.3 3.6 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like XPC-binding PF09280.6 EME85282.1 - 2.8e-24 84.3 14.0 4.9e-24 83.5 9.7 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EME85282.1 - 4.4e-19 67.6 0.5 7.2e-19 66.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EME85282.1 - 2e-16 59.2 3.2 1.1e-08 34.6 0.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EME85282.1 - 1.3e-09 37.6 0.3 2.4e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EME85282.1 - 0.0024 18.3 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 EME85282.1 - 0.0048 16.4 0.0 0.96 9.0 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.1 EME85282.1 - 0.0049 17.0 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EME85282.1 - 0.0075 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME85282.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WIYLD PF10440.4 EME85282.1 - 0.076 12.9 0.4 4 7.4 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Methyltransf_26 PF13659.1 EME85283.1 - 6.9e-12 45.4 0.0 2.1e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME85283.1 - 5.3e-08 33.4 0.0 1.4e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME85283.1 - 9e-08 31.8 0.0 3.7e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EME85283.1 - 2e-07 30.3 0.0 3.6e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 EME85283.1 - 2e-05 24.8 0.0 4.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EME85283.1 - 0.0026 16.9 0.0 0.0093 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF890) MTS PF05175.9 EME85283.1 - 0.0029 16.9 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 EME85283.1 - 0.0049 16.4 0.0 1.7 8.1 0.0 3.0 3 0 0 3 3 3 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 EME85283.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Eco57I PF07669.6 EME85283.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_32 PF13679.1 EME85283.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_ab_N PF02874.18 EME85284.1 - 9.7e-24 83.3 2.1 2.5e-23 82.0 0.7 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.20 EME85284.1 - 8.7e-09 35.1 0.2 1.5e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME85284.1 - 0.0014 19.0 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain DPBB_1 PF03330.13 EME85285.1 - 3.4e-11 42.9 0.0 9.7e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EME85285.1 - 2.3e-05 24.0 0.6 4.8e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 Barwin family BNR PF02012.15 EME85285.1 - 1.3 9.1 4.9 0.69 9.9 1.3 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF3402 PF11882.3 EME85286.1 - 6.9e-130 433.7 0.0 1.2e-129 432.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EME85286.1 - 1.4e-74 250.6 0.0 2.5e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein Vps51 PF08700.6 EME85289.1 - 3.7e-15 55.5 3.0 1.8e-13 50.1 0.0 3.9 4 0 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 EME85289.1 - 0.024 14.5 2.4 0.043 13.6 0.2 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HIG_1_N PF04588.8 EME85290.1 - 1.1e-06 28.2 1.4 2.2e-06 27.2 0.3 2.1 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF4337 PF14235.1 EME85290.1 - 0.79 9.5 10.4 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF947 PF06102.7 EME85291.1 - 4.9e-45 153.3 35.4 4.9e-45 153.3 24.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF947) SET PF00856.23 EME85297.1 - 1.3e-22 80.8 0.2 1.3e-22 80.8 0.2 4.0 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EME85297.1 - 4.2e-13 49.0 8.3 4.2e-13 49.0 5.7 2.0 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EME85297.1 - 2.8e-05 23.5 0.3 8.1e-05 22.0 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 EME85297.1 - 0.015 15.1 3.1 0.035 13.9 2.1 1.7 1 0 0 1 1 1 0 WW domain VHS PF00790.14 EME85298.1 - 0.0039 16.8 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain CFIA_Pcf11 PF11526.3 EME85298.1 - 0.027 14.6 0.4 0.062 13.4 0.3 1.5 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-C2HC_2 PF13913.1 EME85298.1 - 0.3 10.7 1.7 0.61 9.8 0.1 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FadA PF09403.5 EME85299.1 - 0.13 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Adhesion protein FadA HLH PF00010.21 EME85300.1 - 5.2e-13 48.4 0.0 9.2e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 EME85300.1 - 0.0013 18.3 0.7 0.14 11.9 0.1 2.6 3 0 0 3 3 3 1 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EME85300.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF3166 PF11365.3 EME85300.1 - 0.17 12.3 0.3 4.1 7.9 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3166) Pox_A_type_inc PF04508.7 EME85300.1 - 0.19 11.5 1.4 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SAE2 PF08573.5 EME85301.1 - 1.3e-19 70.6 0.2 1.3e-19 70.6 0.1 3.0 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HALZ PF02183.13 EME85301.1 - 0.0032 17.1 6.0 0.29 10.8 0.5 2.7 2 0 0 2 2 2 2 Homeobox associated leucine zipper FlaC_arch PF05377.6 EME85301.1 - 0.051 13.4 0.4 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EME85301.1 - 0.095 12.2 2.3 0.3 10.6 1.6 1.8 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EME85301.1 - 4.9 6.2 9.4 5.5 6.1 0.6 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding F-box-like PF12937.2 EME85302.1 - 1.4e-05 24.7 0.3 2.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME85302.1 - 1.5e-05 24.5 0.2 2.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain zf-CCHC PF00098.18 EME85303.1 - 4.1e-50 165.4 57.4 4.3e-08 32.7 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EME85303.1 - 1e-10 41.0 43.3 0.16 11.6 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EME85303.1 - 8.2e-06 25.4 50.7 0.041 13.6 0.4 7.0 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 EME85303.1 - 4.2e-05 23.1 42.7 0.16 11.7 0.3 6.8 5 1 2 7 7 7 6 Zinc knuckle Arylsulfotran_2 PF14269.1 EME85304.1 - 2.1e-47 161.7 2.0 3.6e-47 160.9 1.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME85304.1 - 2.5e-11 42.7 3.3 6.7e-11 41.3 2.2 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arf PF00025.16 EME85306.1 - 4.9e-42 143.1 0.1 1.4e-27 96.0 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EME85306.1 - 2.4e-14 52.8 0.0 1.8e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME85306.1 - 3.1e-10 39.5 0.0 3.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EME85306.1 - 1.3e-09 37.6 0.0 1.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EME85306.1 - 1.2e-07 32.2 0.0 2.7e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EME85306.1 - 2e-07 30.3 0.0 3.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EME85306.1 - 7.2e-07 28.8 0.1 8.6e-05 22.0 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME85306.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME85306.1 - 0.04 13.2 0.1 0.13 11.5 0.0 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EME85306.1 - 0.043 13.2 0.0 0.089 12.2 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EME85306.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EME85306.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.1 EME85306.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S25 PF03297.10 EME85308.1 - 6.8e-40 135.3 4.2 7.4e-40 135.2 2.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EME85308.1 - 0.0035 16.6 0.2 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EME85308.1 - 0.006 16.2 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.7 EME85308.1 - 0.0089 15.5 0.9 0.016 14.7 0.2 1.7 1 1 1 2 2 2 1 DeoR-like helix-turn-helix domain GntR PF00392.16 EME85308.1 - 0.13 11.7 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family YscJ_FliF_C PF08345.6 EME85308.1 - 0.35 10.8 2.3 1.7 8.6 1.6 1.7 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal Alb1 PF09135.6 EME85310.1 - 3.5e-19 69.4 10.5 6.1e-19 68.6 7.3 1.4 1 0 0 1 1 1 1 Alb1 PB1-F2 PF11986.3 EME85310.1 - 0.032 14.2 1.8 0.052 13.5 1.3 1.4 1 0 0 1 1 1 0 Influenza A Proapoptotic protein NARP1 PF12569.3 EME85310.1 - 2.6 6.6 11.8 3.2 6.4 8.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3328 PF11807.3 EME85312.1 - 2e-27 96.2 0.6 2.1e-27 96.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EME85314.1 - 5.4e-25 88.3 0.1 6.2e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UCH PF00443.24 EME85315.1 - 5.9e-24 84.6 0.0 7.4e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1574 PF07611.6 EME85316.1 - 0.094 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) FctA PF12892.2 EME85317.1 - 0.089 13.6 1.1 0.14 12.9 0.8 1.2 1 0 0 1 1 1 0 T surface-antigen of pili DHHW PF14286.1 EME85317.1 - 0.3 10.3 2.5 0.32 10.2 1.7 1.0 1 0 0 1 1 1 0 DHHW protein MGC-24 PF05283.6 EME85317.1 - 3.1 7.5 8.0 3.7 7.2 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) SpoIIIAH PF12685.2 EME85318.1 - 1.3 8.4 11.3 1.3 8.4 0.0 2.9 3 0 0 3 3 3 0 SpoIIIAH-like protein Tom37_C PF11801.3 EME85318.1 - 2.5 7.9 7.2 0.72 9.7 0.4 2.6 1 1 1 2 2 2 0 Tom37 C-terminal domain Mito_carr PF00153.22 EME85319.1 - 2e-23 81.9 1.0 2.1e-14 52.9 0.1 2.5 3 0 0 3 3 3 2 Mitochondrial carrier protein Med6 PF04934.9 EME85320.1 - 5e-25 87.6 0.0 7.6e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component CMV_1a PF12467.3 EME85320.1 - 0.97 9.7 5.9 1.7 8.9 4.1 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family adh_short PF00106.20 EME85321.1 - 8e-13 48.6 0.0 3.8e-12 46.4 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME85321.1 - 5.4e-07 29.6 0.0 8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 EME85322.1 - 1.8e-17 63.1 2.3 2.6e-17 62.5 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 EME85323.1 - 2.7e-25 89.1 0.3 3.7e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YjeF_N PF03853.10 EME85324.1 - 1e-23 83.7 0.0 1.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus SM-ATX PF14438.1 EME85324.1 - 0.025 14.4 0.1 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Ataxin 2 SM domain LSM PF01423.17 EME85324.1 - 0.054 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 LSM domain Arginase PF00491.16 EME85324.1 - 0.078 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Arginase family adh_short PF00106.20 EME85325.1 - 8.1e-17 61.6 3.7 1.1e-15 58.0 2.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME85325.1 - 1.7e-12 47.6 0.3 3.3e-12 46.6 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME85325.1 - 2.9e-08 33.5 1.6 3.1e-08 33.5 0.1 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EME85325.1 - 0.00053 18.9 0.0 0.00082 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EME85325.1 - 0.0033 16.8 0.1 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME85325.1 - 0.054 12.1 0.2 0.09 11.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EME85325.1 - 0.062 13.4 0.3 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EME85325.1 - 0.12 12.3 0.3 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 EME85326.1 - 4.1e-84 282.7 29.2 4.7e-84 282.5 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME85326.1 - 3.1e-13 49.1 44.8 8.4e-11 41.1 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3HC4_2 PF13923.1 EME85327.1 - 1.2e-08 34.8 8.2 1.9e-08 34.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME85327.1 - 3.5e-08 33.1 6.5 6e-08 32.3 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME85327.1 - 1.7e-07 30.7 7.4 3e-07 30.0 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME85327.1 - 2.3e-07 30.3 5.1 4e-07 29.5 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME85327.1 - 8.4e-07 28.6 4.7 1.6e-06 27.7 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EME85327.1 - 1.1e-05 25.2 5.4 6.5e-05 22.7 4.1 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME85327.1 - 0.0012 18.4 4.6 0.0014 18.3 2.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EME85327.1 - 0.0034 16.8 3.3 0.0068 15.9 2.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PIN PF01850.16 EME85327.1 - 0.14 12.4 0.4 0.32 11.3 0.3 1.6 1 0 0 1 1 1 0 PIN domain zf-Apc11 PF12861.2 EME85327.1 - 0.22 11.3 2.0 0.49 10.2 1.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EME85327.1 - 0.76 9.3 10.0 2 8.0 6.9 1.7 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EME85327.1 - 0.99 9.2 5.1 0.22 11.3 0.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TerY-C PF15616.1 EME85327.1 - 1.3 8.9 4.0 3.3 7.6 2.8 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain DLH PF01738.13 EME85328.1 - 1.1e-27 96.8 0.0 1.2e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EME85328.1 - 1.4e-09 37.8 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME85328.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME85328.1 - 0.072 11.8 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.6 EME85328.1 - 0.16 11.6 0.1 0.61 9.7 0.0 1.7 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DFP PF04127.10 EME85329.1 - 4.5e-13 49.2 0.0 8.9e-05 22.1 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Slu7 PF11708.3 EME85330.1 - 3e-69 233.4 16.1 3e-69 233.4 11.2 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EME85330.1 - 0.013 15.1 1.0 0.027 14.1 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3328 PF11807.3 EME85331.1 - 1.6e-50 171.8 0.3 1.7e-50 171.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) JSRP PF15312.1 EME85332.1 - 0.0018 18.2 0.0 25 4.9 0.0 4.8 5 1 0 5 5 5 2 Junctional sarcoplasmic reticulum protein REGB_T4 PF10715.4 EME85332.1 - 0.12 12.5 0.2 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Endoribonuclease RegB T4-bacteriophage encoded PI3K_rbd PF00794.13 EME85333.1 - 0.0038 17.1 0.0 80 3.2 0.0 5.0 2 2 4 6 6 6 0 PI3-kinase family, ras-binding domain YL1_C PF08265.6 EME85333.1 - 0.033 13.7 1.8 1.4e+02 2.1 0.0 5.2 5 0 0 5 5 5 0 YL1 nuclear protein C-terminal domain SRP9-21 PF05486.7 EME85333.1 - 0.076 12.7 0.0 8.2 6.2 0.0 3.4 2 2 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Glyco_hydro_67M PF07488.7 EME85335.1 - 9e-148 491.4 0.0 1.1e-147 491.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67N PF03648.9 EME85335.1 - 7.5e-26 90.5 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EME85335.1 - 0.0049 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 RRM_1 PF00076.17 EME85336.1 - 7.2e-08 31.9 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME85336.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Prefoldin PF02996.12 EME85336.1 - 0.014 15.0 0.9 0.023 14.3 0.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit TSC22 PF01166.13 EME85336.1 - 0.014 15.3 0.7 0.029 14.3 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4047 PF13256.1 EME85336.1 - 0.021 14.7 0.2 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Tektin PF03148.9 EME85336.1 - 0.025 13.1 1.1 0.039 12.4 0.8 1.2 1 0 0 1 1 1 0 Tektin family DUF972 PF06156.8 EME85336.1 - 0.031 14.6 2.0 0.078 13.3 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) RRM_5 PF13893.1 EME85336.1 - 0.047 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC-167 PF15188.1 EME85336.1 - 0.063 13.2 1.3 0.13 12.2 0.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2216 PF10226.4 EME85336.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Sec20 PF03908.8 EME85336.1 - 0.11 12.1 0.4 0.18 11.4 0.3 1.3 1 0 0 1 1 1 0 Sec20 DUF3866 PF12982.2 EME85336.1 - 0.16 10.9 0.2 0.35 9.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3866) Pyridox_oxidase PF01243.15 EME85338.1 - 2.8e-07 30.4 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HYLS1_C PF15311.1 EME85338.1 - 0.055 13.6 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus 2-oxoacid_dh PF00198.18 EME85341.1 - 6.2e-73 244.8 0.5 7.9e-73 244.5 0.4 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME85341.1 - 2.9e-18 65.2 0.4 1.5e-17 63.0 0.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EME85341.1 - 3.1e-13 49.1 0.9 3.1e-13 49.1 0.6 2.0 2 0 0 2 2 2 1 e3 binding domain Sec7 PF01369.15 EME85342.1 - 9.7e-66 221.0 2.2 9.7e-66 221.0 1.5 2.7 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EME85342.1 - 8.2e-48 162.0 3.6 1.7e-47 160.9 0.1 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EME85342.1 - 4e-30 103.1 6.2 1.1e-29 101.7 0.1 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Aminotran_5 PF00266.14 EME85344.1 - 4.3e-19 68.4 0.0 2.9e-16 59.1 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class-V Aconitase PF00330.15 EME85345.1 - 6.1e-65 219.5 0.0 1.2e-38 132.7 0.0 2.5 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME85345.1 - 4.3e-22 78.6 0.0 1.1e-21 77.2 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.27 EME85346.1 - 2.2e-29 100.2 4.5 6.7e-05 22.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EME85346.1 - 6.5e-05 21.8 1.0 0.14 10.8 0.2 3.6 1 1 2 4 4 4 2 Nup133 N terminal like Sigma70_r1_2 PF00140.15 EME85346.1 - 0.00038 20.0 0.5 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-70 factor, region 1.2 Nup160 PF11715.3 EME85346.1 - 0.0032 15.6 1.4 1 7.4 0.0 3.2 1 1 0 3 3 3 3 Nucleoporin Nup120/160 AA_permease_2 PF13520.1 EME85347.1 - 4.4e-50 170.4 51.1 5.5e-50 170.1 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME85347.1 - 1.1e-24 86.7 40.1 1.4e-24 86.2 27.8 1.1 1 0 0 1 1 1 1 Amino acid permease PLDc PF00614.17 EME85348.1 - 5e-14 51.5 2.3 8.5e-08 31.7 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EME85348.1 - 3.4e-13 49.4 0.1 0.00014 21.5 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain Glyco_hydro_92 PF07971.7 EME85349.1 - 1.1e-152 509.1 4.3 1.5e-152 508.7 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Thioredox_DsbH PF03190.10 EME85350.1 - 8.1e-67 224.0 0.0 1.3e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EME85350.1 - 1.7e-10 40.7 0.0 5.2e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME85350.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 EME85350.1 - 0.046 12.7 0.0 3.7 6.4 0.0 2.7 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Sigma70_r3 PF04539.11 EME85350.1 - 0.12 12.2 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-70 region 3 CAP PF00188.21 EME85351.1 - 9e-16 58.4 3.3 1.9e-15 57.4 2.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF605 PF04652.11 EME85351.1 - 1.2 8.4 13.9 1.6 8.0 9.6 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EME85351.1 - 7.7 4.6 9.3 9.8 4.2 6.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAS_CSE1 PF03378.10 EME85352.1 - 1e-161 538.1 0.1 2.9e-161 536.6 0.1 1.8 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EME85352.1 - 1.9e-148 493.9 2.5 3.7e-148 493.0 1.7 1.5 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EME85352.1 - 2.8e-15 55.9 0.0 1e-14 54.1 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EME85352.1 - 0.13 12.1 3.4 0.91 9.4 0.0 3.6 3 2 0 3 3 3 0 Exportin 1-like protein DUF3684 PF12449.3 EME85353.1 - 0 1308.4 0.0 0 1308.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EME85353.1 - 7.8e-06 25.5 0.0 2.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME85353.1 - 0.002 17.7 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 EME85353.1 - 0.0046 16.8 3.5 0.057 13.2 0.7 2.5 2 0 0 2 2 2 1 WLM domain Reprolysin_5 PF13688.1 EME85353.1 - 0.11 12.4 2.2 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12 Nop25 PF09805.4 EME85353.1 - 5.2 7.1 8.1 15 5.6 5.6 1.8 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nol1_Nop2_Fmu PF01189.12 EME85354.1 - 1.4e-18 67.3 0.2 1.4e-13 50.9 0.1 2.9 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_3 PF01596.12 EME85354.1 - 0.076 12.0 0.1 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase TATR PF03430.8 EME85355.1 - 0.76 8.3 1.5 0.96 8.0 1.1 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Myb_DNA-binding PF00249.26 EME85356.1 - 3.5e-13 49.3 0.5 1.5e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME85356.1 - 3.6e-10 39.8 3.4 1.9e-05 24.6 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain TPR_MLP1_2 PF07926.7 EME85357.1 - 0.0065 16.2 1.1 0.0065 16.2 0.8 1.8 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.4 EME85357.1 - 0.011 15.7 2.4 0.015 15.3 1.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein CorA PF01544.13 EME85357.1 - 0.037 13.0 2.8 0.057 12.4 2.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 EME85357.1 - 0.058 11.7 2.9 0.088 11.2 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EME85357.1 - 0.064 12.8 7.5 0.12 11.9 5.2 1.4 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 EME85357.1 - 0.11 12.3 2.8 0.2 11.4 0.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EME85357.1 - 0.12 11.4 5.8 0.22 10.5 4.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4145 PF13643.1 EME85357.1 - 0.12 12.2 1.2 0.66 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) DUF948 PF06103.6 EME85357.1 - 0.2 11.5 5.3 5.9 6.8 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EME85357.1 - 0.41 9.2 8.6 0.67 8.5 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.1 EME85357.1 - 0.51 10.3 5.5 2 8.3 3.8 2.1 1 1 0 1 1 1 0 FlxA-like protein GAS PF13851.1 EME85357.1 - 0.55 9.3 10.6 1.1 8.4 7.4 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.6 EME85357.1 - 0.61 9.8 9.3 0.29 10.8 2.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 EME85357.1 - 0.97 9.4 9.3 1.7 8.6 5.1 2.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 EME85357.1 - 1.3 9.5 7.4 0.32 11.4 2.3 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.9 EME85357.1 - 1.3 8.8 7.8 0.11 12.3 1.8 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 EME85357.1 - 1.7 8.8 10.5 0.64 10.2 3.8 2.2 2 0 0 2 2 2 0 Syntaxin TMF_DNA_bd PF12329.3 EME85357.1 - 3.2 7.6 12.1 8 6.3 7.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.1 EME85357.1 - 7.1 7.0 11.9 0.89 9.9 0.8 3.1 1 1 2 3 3 3 0 Snapin/Pallidin Romo1 PF10247.4 EME85358.1 - 1.5e-24 85.9 9.8 2.2e-24 85.4 6.8 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EME85358.1 - 0.47 10.5 7.1 1.1 9.3 3.5 1.9 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FHA PF00498.21 EME85359.1 - 4e-16 58.8 0.0 8.9e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain Mnd1 PF03962.10 EME85359.1 - 4.2 7.0 10.7 2.6 7.6 1.3 2.4 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EME85359.1 - 5.1 6.6 7.7 13 5.3 1.6 2.5 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EME85359.1 - 8.9 6.7 10.7 2.5 8.4 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) HAD PF12710.2 EME85360.1 - 4.5e-16 59.5 0.0 5.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME85360.1 - 8.2e-11 42.4 0.0 3e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME85360.1 - 6e-10 39.1 0.0 1.1e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME85360.1 - 3.3e-09 37.4 0.0 9e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EME85360.1 - 0.0024 17.0 0.0 0.29 10.2 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase ADSL_C PF10397.4 EME85360.1 - 0.042 13.8 0.1 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus DUF705 PF05152.7 EME85360.1 - 0.042 12.8 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.8 EME85360.1 - 0.14 11.4 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Ribosomal_S4 PF00163.14 EME85361.1 - 7.9e-30 103.1 1.1 1.5e-29 102.1 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EME85361.1 - 4.3e-13 48.4 1.2 4.3e-13 48.4 0.8 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EME85362.1 - 2.8e-39 132.9 5.4 3.4e-39 132.6 2.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 EME85362.1 - 0.00026 20.4 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Nexin_C PF08628.7 EME85362.1 - 0.083 12.9 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Sorting nexin C terminal TFIIF_alpha PF05793.7 EME85363.1 - 0.33 9.2 21.2 0.18 10.1 11.0 2.6 1 1 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cation_efflux PF01545.16 EME85365.1 - 6.3e-33 114.0 1.6 8.6e-33 113.6 1.1 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3980 PF13140.1 EME85365.1 - 0.15 12.3 2.8 3 8.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) AMP-binding PF00501.23 EME85366.1 - 1.6e-80 270.5 0.0 2.4e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EME85366.1 - 1.2e-62 211.0 0.0 3.5e-62 209.5 0.0 1.8 2 1 1 3 3 3 1 Male sterility protein adh_short PF00106.20 EME85366.1 - 8.9e-38 129.8 3.4 3.3e-33 114.9 0.9 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EME85366.1 - 2.7e-22 79.3 1.9 2.1e-16 60.0 0.6 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EME85366.1 - 8.1e-20 71.6 0.2 2e-19 70.3 0.2 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME85366.1 - 6e-19 68.4 0.0 2.3e-11 43.5 0.0 3.1 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EME85366.1 - 2.6e-11 43.6 0.0 5.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EME85366.1 - 3.8e-09 36.7 0.1 0.0029 17.6 0.4 3.8 2 1 0 2 2 2 2 NADH(P)-binding 3Beta_HSD PF01073.14 EME85366.1 - 5.2e-09 35.1 0.0 1.3e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME85366.1 - 2.1e-08 33.4 0.2 0.00034 19.5 0.0 3.4 3 0 0 3 3 3 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EME85366.1 - 5.7e-06 25.4 0.3 0.07 12.0 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.1 EME85366.1 - 3.8e-05 24.5 0.0 0.00019 22.3 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DFP PF04127.10 EME85366.1 - 0.018 14.6 0.5 0.055 13.0 0.3 1.8 2 0 0 2 2 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 EME85366.1 - 0.035 13.5 0.1 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 EME85366.1 - 0.058 12.6 1.8 35 3.5 0.0 3.9 4 0 0 4 4 4 0 NmrA-like family THF_DHG_CYH_C PF02882.14 EME85366.1 - 0.082 11.9 0.3 0.23 10.5 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EME85366.1 - 0.13 12.0 2.2 0.36 10.6 1.5 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EME85367.1 - 2e-20 72.6 0.1 3.2e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME85367.1 - 1.2e-06 29.4 0.0 3.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME85367.1 - 0.0028 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SDF PF00375.13 EME85368.1 - 9.6e-93 311.0 31.9 1.2e-92 310.7 22.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.1 EME85368.1 - 0.0031 17.1 0.7 0.0031 17.1 0.5 3.0 2 2 0 2 2 2 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase NAD_binding_7 PF13241.1 EME85370.1 - 3.7e-31 107.4 0.0 5.6e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EME85370.1 - 7e-29 98.9 0.1 1.1e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EME85370.1 - 6.7e-14 50.5 0.3 1.1e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EME85370.1 - 0.00074 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EME85370.1 - 0.012 15.7 0.1 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 EME85370.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AAA PF00004.24 EME85371.1 - 1.8e-16 60.4 0.0 2.9e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME85371.1 - 0.00025 21.8 0.4 0.00078 20.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME85371.1 - 0.00063 19.7 0.5 0.0019 18.2 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 EME85371.1 - 0.00092 18.7 0.4 0.034 13.5 0.1 2.6 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_5 PF07728.9 EME85371.1 - 0.0014 18.3 0.1 0.011 15.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME85371.1 - 0.0023 18.0 0.5 0.01 15.9 0.1 2.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EME85371.1 - 0.0049 16.7 0.1 0.0086 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME85371.1 - 0.0072 15.3 0.0 0.076 12.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus GRAM PF02893.15 EME85371.1 - 0.011 15.2 0.2 0.021 14.3 0.0 1.6 2 0 0 2 2 2 0 GRAM domain CPT PF07931.7 EME85371.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.1 EME85371.1 - 0.026 14.4 0.0 0.8 9.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EME85371.1 - 0.027 14.7 1.8 0.1 12.8 1.3 2.3 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 EME85371.1 - 0.033 12.9 0.2 0.16 10.7 0.1 1.9 2 0 0 2 2 2 0 MCM2/3/5 family AAA_19 PF13245.1 EME85371.1 - 0.043 13.5 1.4 0.066 12.9 0.3 1.9 2 1 0 2 2 2 0 Part of AAA domain Viral_helicase1 PF01443.13 EME85371.1 - 0.054 13.0 0.1 0.26 10.7 0.0 2.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 EME85371.1 - 0.063 12.7 0.2 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EME85371.1 - 0.18 11.1 1.6 3.2 7.0 0.3 2.1 2 0 0 2 2 2 0 Thymidylate kinase MACPF PF01823.14 EME85373.1 - 0.0087 15.7 3.5 0.013 15.2 2.4 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Gly-zipper_OmpA PF13436.1 EME85373.1 - 0.014 15.0 1.1 0.014 15.0 0.7 2.4 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Macoilin PF09726.4 EME85373.1 - 0.075 11.3 8.8 0.085 11.1 6.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1178 PF06676.6 EME85373.1 - 0.078 13.1 8.2 0.12 12.5 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) HSP70 PF00012.15 EME85373.1 - 0.16 9.8 10.6 0.19 9.5 7.4 1.0 1 0 0 1 1 1 0 Hsp70 protein ETRAMP PF09716.5 EME85373.1 - 0.17 11.8 4.4 0.48 10.4 3.0 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Terminase_4 PF05119.7 EME85373.1 - 0.19 11.9 3.2 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 Phage terminase, small subunit Borrelia_P83 PF05262.6 EME85373.1 - 0.24 9.6 14.6 0.33 9.1 10.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Vicilin_N PF04702.7 EME85373.1 - 0.37 10.3 12.3 0.53 9.8 8.5 1.1 1 0 0 1 1 1 0 Vicilin N terminal region Prominin PF05478.6 EME85373.1 - 0.39 8.1 1.3 0.49 7.8 0.9 1.1 1 0 0 1 1 1 0 Prominin FLO_LFY PF01698.11 EME85373.1 - 1.1 8.0 9.1 1.4 7.7 6.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Med11 PF10280.4 EME85373.1 - 1.3 9.1 5.5 4.5 7.3 3.8 1.7 1 1 0 1 1 1 0 Mediator complex protein ATP-synt_B PF00430.13 EME85373.1 - 5 6.9 22.0 7.2 6.4 3.0 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DivIVA PF05103.8 EME85373.1 - 9.2 6.3 17.1 1 9.4 7.0 2.1 1 1 1 2 2 2 0 DivIVA protein Peptidase_C12 PF01088.16 EME85374.1 - 4.8e-66 222.0 0.0 1.8e-65 220.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 BCDHK_Adom3 PF10436.4 EME85376.1 - 3.4e-41 140.4 0.0 5.3e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EME85376.1 - 1.4e-12 47.2 0.3 2.4e-11 43.3 0.2 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Whi5 PF08528.6 EME85377.1 - 1.2e-08 34.3 0.0 2.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Whi5 like tRNA-synt_1c PF00749.16 EME85379.1 - 1e-96 323.3 0.0 1.3e-96 322.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EME85379.1 - 5.4e-35 120.6 0.0 1.3e-34 119.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Tyrosinase PF00264.15 EME85380.1 - 1e-40 140.3 0.4 1.2e-40 140.0 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pol_alpha_B_N PF08418.5 EME85382.1 - 2.3e-59 200.9 0.3 3.1e-59 200.5 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EME85382.1 - 4.1e-35 120.9 0.0 6.1e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FG-GAP_2 PF14312.1 EME85382.1 - 0.081 12.9 0.1 3 7.9 0.0 2.9 3 0 0 3 3 3 0 FG-GAP repeat UBA_4 PF14555.1 EME85383.1 - 0.00036 20.0 0.1 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.15 EME85383.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain FYVE PF01363.16 EME85383.1 - 0.013 15.4 0.7 0.023 14.5 0.5 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_5 PF14634.1 EME85383.1 - 0.021 14.5 9.1 0.038 13.7 6.3 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME85383.1 - 0.15 12.1 8.9 0.052 13.5 4.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME85383.1 - 0.36 10.6 9.0 0.65 9.8 6.2 1.5 1 1 0 1 1 1 0 Ring finger domain Baculo_IE-1 PF05290.6 EME85383.1 - 0.62 9.7 3.3 1 9.0 2.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EME85383.1 - 1.4 8.6 7.9 2.3 7.9 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FA_hydroxylase PF04116.8 EME85384.1 - 5.3e-18 65.4 12.3 5.3e-18 65.4 8.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RdRP PF05183.7 EME85385.1 - 8.6e-86 288.8 0.0 1.4e-85 288.2 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase TCTP PF00838.12 EME85386.1 - 5.1e-66 221.7 2.2 5.7e-66 221.5 1.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S8 PF00410.14 EME85387.1 - 3.7e-25 88.2 0.1 5.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Astacin PF01400.19 EME85388.1 - 0.00014 21.2 0.8 0.00034 20.0 0.2 1.8 2 0 0 2 2 2 1 Astacin (Peptidase family M12A) DUF4071 PF13281.1 EME85388.1 - 0.2 10.4 0.1 0.31 9.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PDEase_II PF02112.10 EME85389.1 - 9.7e-50 169.3 0.0 4.1e-21 75.2 0.0 3.9 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EME85389.1 - 0.0058 16.1 0.0 0.038 13.5 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain GDPD PF03009.12 EME85392.1 - 2.2e-31 109.3 0.0 3.2e-31 108.7 0.0 1.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Sugar_tr PF00083.19 EME85393.1 - 5.6e-09 35.0 4.8 5.8e-09 35.0 3.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PfkB PF00294.19 EME85398.1 - 6.4e-67 225.8 0.2 7.8e-67 225.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UCR_14kD PF02271.11 EME85398.1 - 0.017 14.8 0.2 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Fer2_3 PF13085.1 EME85398.1 - 0.058 13.2 0.1 0.091 12.5 0.0 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF221 PF02714.10 EME85399.1 - 2.9e-105 351.7 27.3 2.9e-105 351.7 18.9 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME85399.1 - 2.4e-43 147.4 8.9 2e-42 144.4 0.6 3.5 2 1 0 2 2 2 2 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EME85399.1 - 8.7e-15 54.3 0.5 3.1e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EME85399.1 - 8.9e-07 29.3 22.3 0.00035 21.0 8.8 3.6 3 2 0 3 3 3 2 Domain of unknown function (DUF4463) V_ATPase_I PF01496.14 EME85399.1 - 0.0012 16.8 1.1 0.0012 16.8 0.8 2.4 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family CorA PF01544.13 EME85400.1 - 8.2e-15 54.5 0.1 1.8e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HSP20 PF00011.16 EME85401.1 - 1.3e-12 47.4 0.0 1.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family SNF2_N PF00176.18 EME85402.1 - 1.1e-71 241.1 0.0 1.6e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME85402.1 - 9.1e-13 47.8 0.0 2.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EME85402.1 - 1.8e-07 30.2 1.7 6.5e-07 28.4 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EME85402.1 - 1.1e-06 28.6 0.3 4.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit vMSA PF00695.14 EME85402.1 - 0.22 10.6 1.5 0.38 9.8 1.1 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Cupin_2 PF07883.6 EME85403.1 - 9.7e-13 47.4 0.2 1.9e-12 46.4 0.2 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EME85403.1 - 1.6e-05 24.3 0.0 2.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.3 EME85403.1 - 0.00068 19.5 0.0 0.0028 17.6 0.0 1.9 1 1 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.14 EME85403.1 - 0.067 12.8 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Sec63 PF02889.11 EME85404.1 - 8.9e-38 130.2 0.0 1.2e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EME85404.1 - 4.4e-15 55.1 0.1 1.2e-14 53.8 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Zip PF02535.17 EME85405.1 - 0.00058 18.9 3.0 0.00058 18.9 2.0 2.1 3 0 0 3 3 3 1 ZIP Zinc transporter DUF2796 PF10986.3 EME85405.1 - 0.097 12.6 20.3 0.27 11.1 10.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Trypan_PARP PF05887.6 EME85405.1 - 0.16 11.7 4.3 0.29 10.9 3.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BAF1_ABF1 PF04684.8 EME85405.1 - 0.28 9.9 15.0 0.64 8.8 10.4 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CbtA PF09490.5 EME85405.1 - 1.2 8.3 4.1 2.2 7.5 2.8 1.4 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) MFS_1 PF07690.11 EME85406.1 - 2.5e-34 118.5 42.7 1.7e-33 115.7 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CRT-like PF08627.5 EME85406.1 - 0.078 12.9 0.3 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 CRT-like ESSS PF10183.4 EME85406.1 - 0.23 11.8 1.6 1.7 9.0 0.1 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4202 PF13875.1 EME85407.1 - 5.1e-72 241.3 0.5 5.8e-72 241.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF2102 PF09875.4 EME85407.1 - 0.053 13.0 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Tom5 PF10642.4 EME85409.1 - 0.00014 21.4 0.7 0.00014 21.4 0.5 1.7 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase DUF3382 PF11862.3 EME85409.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Med26 PF08711.6 EME85410.1 - 6.4e-10 38.3 0.1 1.3e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.1 EME85411.1 - 5.6e-38 129.7 3.8 8.4e-38 129.2 1.3 2.2 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EME85411.1 - 1.4e-07 31.6 31.7 2.4e-07 30.9 22.0 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region TBCA PF02970.11 EME85411.1 - 0.031 14.3 0.4 0.031 14.3 0.3 2.7 3 0 0 3 3 3 0 Tubulin binding cofactor A CHCH PF06747.8 EME85412.1 - 3.9e-07 29.8 7.1 3.9e-07 29.8 4.9 2.4 3 0 0 3 3 3 1 CHCH domain Cmc1 PF08583.5 EME85412.1 - 0.043 13.5 13.0 0.097 12.4 3.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EME85412.1 - 0.84 9.7 10.5 1.4 8.9 4.2 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EME85412.1 - 1.4 8.9 11.0 2 8.4 3.1 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 EME85412.1 - 2.2 8.2 6.0 8.4 6.4 4.2 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Chitin_synth_2 PF03142.10 EME85413.1 - 6.9e-25 87.4 2.1 9.6e-24 83.6 0.8 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EME85413.1 - 3.4e-17 62.8 1.9 3.4e-17 62.8 1.3 2.8 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EME85413.1 - 8.5e-17 61.7 0.0 1.6e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EME85413.1 - 0.00015 21.5 0.0 0.034 13.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 G-alpha PF00503.15 EME85414.1 - 2.6e-130 434.6 0.2 3e-130 434.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EME85414.1 - 1e-15 57.4 0.9 8.8e-11 41.3 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME85414.1 - 0.0002 20.5 1.6 0.02 14.0 1.1 2.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME85414.1 - 0.00096 19.6 0.0 0.65 10.5 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EME85414.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EME85414.1 - 0.14 11.5 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EME85415.1 - 1.4e-71 240.6 0.0 1.8e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME85415.1 - 2.8e-31 108.5 0.0 3.4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EME85415.1 - 4.3e-05 22.6 0.0 0.00015 20.8 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EME85415.1 - 0.00028 19.9 0.0 0.024 13.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EME85415.1 - 0.00048 19.9 0.0 0.00098 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME85415.1 - 0.024 14.0 0.1 0.046 13.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family ETF PF01012.16 EME85416.1 - 4.2e-39 133.8 0.2 1.3e-38 132.3 0.0 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EME85416.1 - 5.2e-35 118.9 0.0 1e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Avl9 PF09794.4 EME85417.1 - 2.7e-134 447.4 0.0 3.5e-134 447.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EME85417.1 - 2.2e-11 43.5 0.3 2.8e-10 39.9 0.2 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EME85417.1 - 1.4e-10 40.8 0.2 0.00048 19.8 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DENN PF02141.16 EME85417.1 - 0.066 12.9 2.4 0.096 12.3 0.3 2.1 2 1 0 2 2 2 0 DENN (AEX-3) domain PAN_4 PF14295.1 EME85418.1 - 2.3e-09 36.8 11.1 0.0061 16.2 0.2 3.9 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.7 EME85418.1 - 0.00023 20.6 11.1 0.0069 15.9 0.3 3.5 3 0 0 3 3 3 2 PAN-like domain Mucin PF01456.12 EME85418.1 - 3.3 7.4 30.4 0.071 12.8 15.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein VP4_haemagglut PF00426.13 EME85418.1 - 7.1 4.4 7.1 9.5 4.0 4.9 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Sugar_tr PF00083.19 EME85419.1 - 8.6e-35 120.1 18.8 1.8e-34 119.1 13.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME85419.1 - 5.2e-33 114.2 21.1 5.2e-33 114.2 14.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sec62 PF03839.11 EME85420.1 - 7.2e-53 179.2 4.2 7.2e-53 179.2 2.9 1.7 2 1 0 2 2 2 1 Translocation protein Sec62 Thiolase_N PF00108.18 EME85421.1 - 5.5e-70 235.3 0.0 8e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME85421.1 - 2.2e-42 143.3 0.1 4.6e-42 142.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EME85421.1 - 0.0019 17.8 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EME85421.1 - 0.089 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AcetylCoA_hydro PF02550.10 EME85422.1 - 5.8e-52 176.3 0.0 8.6e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EME85422.1 - 1e-38 132.4 0.0 1.8e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Peptidase_S55 PF05580.7 EME85422.1 - 0.0024 17.3 0.1 0.0038 16.7 0.1 1.2 1 0 0 1 1 1 1 SpoIVB peptidase S55 DUF1772 PF08592.6 EME85423.1 - 7.2e-09 35.4 0.8 8.9e-09 35.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2721 PF11026.3 EME85423.1 - 0.012 15.1 0.3 0.035 13.7 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF4149 PF13664.1 EME85423.1 - 0.66 10.0 3.5 0.4 10.7 0.6 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) XPG_I PF00867.13 EME85424.1 - 3.4e-23 81.4 0.0 6.8e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EME85424.1 - 0.004 17.3 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain MFS_1 PF07690.11 EME85425.1 - 5.7e-38 130.5 30.8 7.8e-38 130.0 21.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM169 PF15052.1 EME85425.1 - 3.1 7.6 13.5 0.031 14.1 1.5 2.9 3 0 0 3 3 3 0 TMEM169 protein family COesterase PF00135.23 EME85427.1 - 8.8e-103 344.8 0.1 1.2e-102 344.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME85427.1 - 9.4e-06 25.3 0.0 2.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EME85428.1 - 8.4e-09 35.3 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold B-block_TFIIIC PF04182.7 EME85429.1 - 1.8e-16 59.7 0.0 6.6e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EME85429.1 - 0.017 14.7 0.8 1.1 8.9 0.0 3.3 3 0 0 3 3 3 0 MarR family Sugar_tr PF00083.19 EME85430.1 - 1.4e-91 307.3 18.9 3.1e-91 306.2 13.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Aldo_ket_red PF00248.16 EME85430.1 - 1.1e-50 172.0 0.0 1.5e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EME85430.1 - 9.3e-21 73.9 20.9 9.3e-21 73.9 14.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EME85431.1 - 2.4e-05 23.3 0.1 5.9e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME85431.1 - 0.02 14.7 1.0 0.037 13.9 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 EME85432.1 - 2.7e-27 95.5 0.2 2.9e-27 95.4 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EME85432.1 - 0.00048 19.1 0.1 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EME85432.1 - 0.12 11.2 0.2 0.22 10.4 0.0 1.5 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Aldo_ket_red PF00248.16 EME85433.1 - 1.2e-62 211.2 0.0 1.5e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-A20 PF01754.11 EME85433.1 - 0.37 10.4 1.4 0.75 9.4 1.0 1.4 1 0 0 1 1 1 0 A20-like zinc finger Epimerase PF01370.16 EME85434.1 - 8.9e-22 77.6 0.0 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME85434.1 - 2e-11 43.1 0.0 2.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME85434.1 - 1.3e-08 34.0 0.0 3e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EME85434.1 - 3.4e-07 29.4 0.0 8e-07 28.2 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EME85434.1 - 7.7e-07 29.1 0.0 6.1e-06 26.2 0.0 2.4 3 1 0 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EME85434.1 - 5e-06 26.6 0.0 7.6e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Ldh_1_N PF00056.18 EME85434.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EME85434.1 - 0.0009 18.3 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EME85434.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EME85434.1 - 0.007 15.2 0.0 0.036 12.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EME85434.1 - 0.14 12.0 0.1 0.53 10.1 0.0 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus BNR_2 PF13088.1 EME85435.1 - 9.9e-69 231.6 0.5 1.2e-68 231.3 0.4 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EME85435.1 - 0.0092 15.6 22.8 0.56 10.2 0.7 5.9 6 0 0 6 6 6 3 BNR/Asp-box repeat Sugar_tr PF00083.19 EME85436.1 - 2.7e-95 319.6 23.3 2.5e-94 316.4 16.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME85436.1 - 2.1e-25 89.1 23.8 2.1e-25 89.1 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OmpH PF03938.9 EME85437.1 - 0.031 14.2 10.3 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2500 PF10694.4 EME85437.1 - 0.51 10.3 2.4 1.5 8.8 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Asp PF00026.18 EME85439.1 - 1.9e-69 234.3 14.1 2.2e-69 234.1 9.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EME85439.1 - 4e-05 24.0 1.0 0.0025 18.3 0.5 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 EME85439.1 - 0.004 17.1 1.1 0.004 17.1 0.8 2.3 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal Pro-kuma_activ PF09286.6 EME85440.1 - 2.6e-44 150.7 0.2 5.9e-44 149.5 0.2 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME85440.1 - 2.9e-12 46.3 4.8 4.6e-12 45.6 3.3 1.4 1 0 0 1 1 1 1 Subtilase family Pectate_lyase_3 PF12708.2 EME85443.1 - 7.5e-76 255.1 19.1 1e-65 222.0 4.6 3.6 3 1 1 4 4 4 2 Pectate lyase superfamily protein Beta_helix PF13229.1 EME85443.1 - 0.0014 18.4 4.7 0.0014 18.4 3.3 2.5 2 0 0 2 2 2 1 Right handed beta helix region End_N_terminal PF12218.3 EME85443.1 - 0.0044 16.4 2.7 1.9 7.9 0.1 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase adh_short PF00106.20 EME85445.1 - 4e-29 101.6 2.6 5.8e-29 101.1 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME85445.1 - 2.8e-25 89.4 0.0 4.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME85445.1 - 1.7e-14 53.8 1.1 2.8e-14 53.1 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME85445.1 - 5.9e-05 22.6 0.0 0.00027 20.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Redoxin PF08534.5 EME85446.1 - 2.5e-30 104.9 0.0 3e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EME85446.1 - 2e-13 50.0 0.0 2.6e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EME85446.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like CBS PF00571.23 EME85448.1 - 2.3e-23 81.6 5.0 1e-10 41.1 0.1 4.2 4 0 0 4 4 4 3 CBS domain PP2C PF00481.16 EME85449.1 - 3.4e-64 216.6 0.1 1.3e-52 178.6 0.0 3.1 1 1 1 3 3 3 3 Protein phosphatase 2C Snf7 PF03357.16 EME85451.1 - 1.8e-39 134.8 21.3 1.8e-39 134.8 14.8 1.3 2 0 0 2 2 2 1 Snf7 DUF1188 PF06690.6 EME85451.1 - 0.03 13.4 0.1 0.056 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1188) WASH_WAHD PF11945.3 EME85451.1 - 0.037 13.3 0.4 0.061 12.6 0.1 1.4 1 1 0 1 1 1 0 WAHD domain of WASH complex GGDN PF05165.7 EME85451.1 - 0.048 12.7 3.9 0.27 10.2 0.2 2.1 1 1 1 2 2 2 0 GGDN family V_ATPase_I PF01496.14 EME85451.1 - 0.086 10.6 5.6 0.1 10.4 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YlqD PF11068.3 EME85451.1 - 0.098 12.7 21.3 1 9.4 7.1 2.2 1 1 1 2 2 2 0 YlqD protein Ist1 PF03398.9 EME85451.1 - 0.17 11.2 6.4 0.3 10.4 4.5 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway PMC2NT PF08066.7 EME85451.1 - 1 9.7 4.4 1.6 9.0 0.5 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Remorin_C PF03763.8 EME85451.1 - 3.3 7.2 10.4 4 7.0 6.4 1.8 1 1 0 1 1 1 0 Remorin, C-terminal region TPR_MLP1_2 PF07926.7 EME85451.1 - 7.2 6.3 13.9 15 5.3 9.5 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 EME85451.1 - 8 6.5 9.1 0.81 9.6 2.7 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Hom_end_hint PF05203.11 EME85451.1 - 9.7 5.8 7.3 14 5.3 4.1 1.7 1 1 1 2 2 2 0 Hom_end-associated Hint Dynamin_N PF00350.18 EME85452.1 - 7.4e-15 55.1 0.0 7.4e-15 55.1 0.0 2.6 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EME85452.1 - 7.6e-09 35.5 0.0 2.9e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME85452.1 - 2.6e-06 26.9 0.3 2.5e-05 23.8 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.4 EME85452.1 - 5e-06 26.0 1.3 3.4e-05 23.3 0.9 2.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) UPF0444 PF15475.1 EME85452.1 - 0.016 15.2 2.0 0.037 14.0 1.4 1.5 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Miro PF08477.8 EME85452.1 - 0.02 15.3 0.1 2.1 8.8 0.0 3.3 2 1 1 3 3 3 0 Miro-like protein IIGP PF05049.8 EME85452.1 - 0.035 12.9 0.0 0.074 11.8 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EME85452.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EME85452.1 - 0.21 12.4 0.8 1.7 9.5 0.0 2.9 3 1 1 4 4 4 0 AAA domain Abhydrolase_5 PF12695.2 EME85453.1 - 4.7e-08 32.9 0.0 1.1e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME85453.1 - 3e-07 30.5 0.1 7.7e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EME85453.1 - 2.5e-06 26.9 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EME85453.1 - 1.2e-05 24.9 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EME85453.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3224 PF11528.3 EME85453.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) Lipase_3 PF01764.20 EME85453.1 - 0.068 12.7 0.3 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF533 PF04391.7 EME85453.1 - 3.6 6.9 6.9 1.1 8.6 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF533) 6PF2K PF01591.13 EME85454.1 - 2.5e-62 209.8 0.0 3.6e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EME85454.1 - 1.3e-23 83.7 1.0 2e-23 83.2 0.7 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EME85454.1 - 0.00011 22.0 0.3 0.00062 19.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EME85454.1 - 0.00015 22.6 0.1 0.00055 20.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 EME85454.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 EME85454.1 - 0.14 11.7 0.0 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Porin_3 PF01459.17 EME85455.1 - 8e-67 225.4 0.0 9.2e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin DIOX_N PF14226.1 EME85456.1 - 3.8e-19 69.3 0.0 6e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME85456.1 - 1.9e-15 56.9 0.0 3.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 EME85457.1 - 4e-07 29.8 12.0 6.7e-07 29.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EME85458.1 - 3e-18 66.2 0.0 4.4e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME85458.1 - 4.2e-07 29.8 0.0 1.1e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EME85458.1 - 3.6e-06 26.9 0.0 2.2e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AcylCoA_dehyd_C PF12186.3 EME85458.1 - 0.076 12.8 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal GCV_T PF01571.16 EME85459.1 - 1.1e-16 60.8 0.0 3.4e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME85459.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 EME85460.1 - 1.2e-22 79.3 0.7 3.1e-22 78.0 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EME85460.1 - 0.016 14.8 0.1 0.085 12.5 0.1 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME85460.1 - 0.024 14.6 0.0 0.082 12.8 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME85460.1 - 0.087 12.6 0.3 0.31 10.8 0.2 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DCP2 PF05026.8 EME85461.1 - 1.1e-33 115.0 0.1 1.7e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EME85461.1 - 1.6e-17 63.4 0.0 3.5e-17 62.3 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain PUF PF00806.14 EME85462.1 - 1.8e-46 153.0 5.7 1.6e-07 30.3 0.0 6.3 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Fer4_19 PF06902.6 EME85462.1 - 0.078 12.8 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Peptidase_C15 PF01470.12 EME85462.1 - 0.097 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyroglutamyl peptidase ADK PF00406.17 EME85464.1 - 2.5e-61 205.9 0.1 3.8e-61 205.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EME85464.1 - 1e-14 53.8 0.0 2.4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EME85464.1 - 1.7e-07 32.0 0.1 2.8e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME85464.1 - 8e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EME85464.1 - 0.0016 17.6 0.1 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.17 EME85464.1 - 0.0021 17.5 0.2 0.0034 16.8 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EME85464.1 - 0.023 15.0 1.8 0.024 14.9 0.2 1.9 2 1 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 EME85464.1 - 0.045 13.8 1.7 0.051 13.7 0.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EME85464.1 - 0.2 11.1 1.4 0.41 10.1 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator AAA_2 PF07724.9 EME85466.1 - 2.3e-40 138.3 0.0 1.3e-39 135.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EME85466.1 - 3.8e-15 56.2 0.0 7.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EME85466.1 - 3.8e-11 42.7 0.0 8.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EME85466.1 - 6.9e-08 32.3 0.0 2.1e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME85466.1 - 6.7e-05 22.9 2.3 0.00038 20.5 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME85466.1 - 0.00024 21.2 0.8 0.0048 17.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EME85466.1 - 0.00024 20.3 0.5 0.015 14.4 0.1 2.7 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME85466.1 - 0.00069 19.1 0.0 0.066 12.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 EME85466.1 - 0.00078 20.2 0.3 0.0038 18.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 EME85466.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EME85466.1 - 0.0027 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME85466.1 - 0.009 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 EME85466.1 - 0.0091 14.8 0.9 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family RuvB_N PF05496.7 EME85466.1 - 0.01 14.9 0.1 0.053 12.5 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EME85466.1 - 0.014 15.0 0.1 0.071 12.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EME85466.1 - 0.023 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME85466.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EME85466.1 - 0.056 13.3 1.0 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EME85466.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EME85466.1 - 0.14 11.6 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EME85466.1 - 0.16 11.6 0.2 0.66 9.6 0.1 2.0 1 1 0 1 1 1 0 NACHT domain DUF1796 PF08795.5 EME85468.1 - 0.086 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Peptidase_S68 PF10461.4 EME85468.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase S68 CRAL_TRIO PF00650.15 EME85470.1 - 3.6e-35 120.7 0.0 5.1e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EME85470.1 - 1.9e-10 40.7 0.0 4.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EME85470.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Abhydrolase_1 PF00561.15 EME85471.1 - 7.1e-13 48.6 0.0 2e-11 43.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME85471.1 - 1.6e-09 38.0 0.0 2.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME85471.1 - 0.002 17.4 0.0 0.0064 15.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME85471.1 - 0.0041 16.8 0.3 0.059 13.1 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Flavin_Reduct PF01613.13 EME85472.1 - 3.5e-17 62.6 0.0 4.8e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain McyA_C PF12593.3 EME85474.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Microcystin synthetase C terminal ADH_zinc_N_2 PF13602.1 EME85476.1 - 4.8e-21 75.9 0.0 1.4e-20 74.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase dCMP_cyt_deam_1 PF00383.17 EME85477.1 - 4.5e-10 39.0 0.3 7.5e-10 38.3 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EME85477.1 - 0.0037 16.9 0.5 0.0046 16.6 0.4 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MFS_1 PF07690.11 EME85479.1 - 1e-47 162.6 40.4 2.2e-46 158.2 28.3 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME85479.1 - 1.3e-18 66.5 10.7 1.3e-18 66.5 7.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PgaD PF13994.1 EME85479.1 - 5.2 6.5 6.5 0.92 8.9 1.7 1.8 2 0 0 2 2 2 0 PgaD-like protein Cellulase PF00150.13 EME85480.1 - 2.1e-30 105.8 2.2 2.7e-30 105.5 1.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EME85481.1 - 2.8e-40 138.1 31.2 2.8e-40 138.1 21.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily PTCB-BRCT PF12738.2 EME85483.1 - 1.5e-42 143.2 0.1 8.5e-21 73.5 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EME85483.1 - 6.1e-30 103.2 0.1 5.6e-13 48.8 0.0 4.3 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.17 EME85485.1 - 2e-23 82.9 0.0 1.7e-22 80.0 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EME85485.1 - 2.3e-08 33.9 0.0 5.5e-05 23.0 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CRF PF00473.12 EME85485.1 - 0.16 12.1 0.3 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family IF-2B PF01008.12 EME85486.1 - 3.5e-76 255.8 0.0 4.4e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family HTH_34 PF13601.1 EME85486.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Plasmodium_Vir PF05795.6 EME85486.1 - 5 6.2 6.7 13 4.8 4.7 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF3414 PF11894.3 EME85487.1 - 1.3e-254 847.8 10.6 2.7e-253 843.4 7.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3414) F-box-like_2 PF13013.1 EME85488.1 - 0.18 11.5 1.8 1.2 8.9 0.1 2.7 3 1 0 3 3 3 0 F-box-like domain SDA1 PF05285.7 EME85489.1 - 1.3e-83 280.9 46.1 8.4e-83 278.3 25.4 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EME85489.1 - 2.4e-21 75.7 0.1 6.1e-21 74.4 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain DUF829 PF05705.9 EME85490.1 - 3.7e-41 141.4 0.0 4.2e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EME85490.1 - 0.0025 17.7 0.2 0.0092 15.8 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family S1-P1_nuclease PF02265.11 EME85491.1 - 5.3e-73 245.7 0.1 6.1e-73 245.5 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Prp19_bind PF06991.6 EME85492.1 - 4.6e-44 150.7 31.7 4.6e-44 150.7 22.0 2.0 2 0 0 2 2 2 2 Splicing factor, Prp19-binding domain Gelsolin PF00626.17 EME85494.1 - 1.4e-08 34.2 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Gelsolin repeat Phage_GPO PF05929.6 EME85495.1 - 0.0014 17.9 1.4 0.0015 17.8 1.0 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase MAP7 PF05672.6 EME85495.1 - 0.004 16.5 9.8 0.0045 16.3 6.8 1.1 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family DUF2854 PF11016.3 EME85495.1 - 0.054 13.0 2.2 0.069 12.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) FUSC PF04632.7 EME85495.1 - 7.9 4.7 8.7 1.7 6.9 3.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Arf PF00025.16 EME85496.1 - 2e-66 222.5 1.3 2.3e-66 222.3 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EME85496.1 - 3.8e-12 45.5 1.5 9.5e-07 27.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EME85496.1 - 7.8e-12 44.8 0.0 9.1e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EME85496.1 - 2.7e-09 36.5 0.0 3.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME85496.1 - 3.9e-09 36.4 0.1 8.3e-09 35.4 0.1 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EME85496.1 - 6.3e-09 36.3 0.0 8.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EME85496.1 - 1.7e-07 30.6 0.0 2.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EME85496.1 - 4.9e-07 29.3 0.0 8e-05 22.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EME85496.1 - 0.0045 17.8 0.1 0.0064 17.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME85496.1 - 0.0055 17.0 0.1 0.0069 16.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EME85496.1 - 0.02 14.1 0.4 0.071 12.3 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.10 EME85496.1 - 0.05 13.3 0.1 0.075 12.7 0.1 1.4 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.13 EME85496.1 - 0.05 12.6 0.2 0.11 11.5 0.1 1.6 1 1 1 2 2 2 0 6-phosphofructo-2-kinase CdhD PF03599.11 EME85496.1 - 0.052 12.0 0.0 0.073 11.5 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit PduV-EutP PF10662.4 EME85496.1 - 0.072 12.5 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EME85496.1 - 0.088 12.7 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Not3 PF04065.10 EME85497.1 - 0.005 16.1 0.1 0.0084 15.3 0.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Acetyltransf_4 PF13420.1 EME85497.1 - 0.019 14.8 0.1 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TAF4 PF05236.9 EME85498.1 - 1.9e-13 50.3 14.3 4.6e-11 42.4 6.8 3.4 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family DUF2570 PF10828.3 EME85498.1 - 0.032 13.8 0.8 0.032 13.8 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) DUF2325 PF10087.4 EME85498.1 - 0.052 13.3 0.0 0.17 11.7 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Herpes_UL25 PF01499.11 EME85498.1 - 2.5 6.3 9.5 3.8 5.6 6.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family CPSF73-100_C PF11718.3 EME85499.1 - 2e-63 213.6 0.0 1.5e-62 210.8 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EME85499.1 - 1.6e-30 105.6 0.0 5.9e-30 103.8 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EME85499.1 - 1.2e-15 57.6 0.2 2.3e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME85499.1 - 4.8e-10 39.3 0.3 1.1e-09 38.1 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EME85499.1 - 7.1e-07 28.9 0.2 1.5e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EME85499.1 - 2.3e-05 24.1 0.3 9.6e-05 22.1 0.2 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Tyr-DNA_phospho PF06087.7 EME85501.1 - 1.9e-74 250.9 0.0 2.2e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EME85501.1 - 6.7e-05 22.6 0.0 0.00062 19.5 0.0 2.1 2 0 0 2 2 2 1 PLD-like domain PQ-loop PF04193.9 EME85502.1 - 1.6e-35 120.4 8.2 2.9e-17 61.9 2.2 2.3 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EME85502.1 - 0.0079 16.0 0.2 0.05 13.4 0.1 2.1 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange F-box PF00646.28 EME85503.1 - 1.3e-09 37.4 1.8 1.7e-09 37.1 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME85503.1 - 1.7e-06 27.6 0.0 4.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EME85503.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 PRANC domain F-box PF00646.28 EME85504.1 - 1.8e-07 30.6 0.1 4.7e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME85504.1 - 0.00031 20.3 0.0 0.00096 18.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EME85504.1 - 0.036 14.0 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain F-box-like_2 PF13013.1 EME85504.1 - 0.069 12.8 0.3 0.11 12.2 0.2 1.5 1 1 0 1 1 1 0 F-box-like domain DUF2407 PF10302.4 EME85505.1 - 0.00034 20.7 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EME85505.1 - 0.00047 19.4 0.0 0.0016 17.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Tudor-knot PF11717.3 EME85505.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain U79_P34 PF03064.11 EME85505.1 - 0.24 10.9 5.3 0.59 9.6 3.7 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PS_Dcarbxylase PF02666.10 EME85506.1 - 2.7e-82 274.9 0.0 2.5e-81 271.7 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase p450 PF00067.17 EME85507.1 - 3.5e-64 217.0 0.0 4.1e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adenylsucc_synt PF00709.16 EME85507.1 - 0.029 13.0 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase GST_C PF00043.20 EME85508.1 - 3e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME85508.1 - 6.4e-05 22.7 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME85508.1 - 0.0015 18.6 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 EME85510.1 - 4.7e-34 117.6 28.2 4.7e-34 117.6 19.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3176 PF11374.3 EME85511.1 - 2.8e-08 33.6 0.9 5.9e-08 32.5 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) CYSTM PF12734.2 EME85511.1 - 2.4 8.3 5.7 4.8 7.3 4.0 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance p450 PF00067.17 EME85512.1 - 3e-62 210.6 0.0 4.8e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 EME85514.1 - 3.2e-66 223.5 0.0 4.4e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Hce2 PF14856.1 EME85515.1 - 1.1e-16 60.5 0.6 2.2e-16 59.5 0.4 1.5 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Oxysterol_BP PF01237.13 EME85516.1 - 5.2e-129 429.7 0.0 1.1e-128 428.7 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 EME85516.1 - 1e-17 64.2 0.2 2.2e-11 43.9 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EME85516.1 - 1e-16 60.5 0.2 1.5e-10 40.9 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EME85516.1 - 1e-15 56.6 0.1 6.1e-06 25.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EME85516.1 - 2.9e-14 53.0 0.1 2.5e-05 24.6 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EME85516.1 - 1.1e-11 44.8 0.2 2.3e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.1 EME85516.1 - 6e-10 38.3 0.0 0.0033 17.5 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.1 EME85516.1 - 1.6e-09 37.9 0.7 4.6e-09 36.5 0.5 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EME85516.1 - 1.8e-06 27.8 0.4 4.3e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain OmpH PF03938.9 EME85516.1 - 8.9 6.2 12.2 0.92 9.4 0.6 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Arylesterase PF01731.15 EME85517.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Arylesterase VWA PF00092.23 EME85518.1 - 3.1e-09 36.8 0.0 8.9e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EME85518.1 - 1.3e-08 35.1 0.0 1.9e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EME85518.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus FTR1 PF03239.9 EME85520.1 - 6.5e-89 297.8 6.3 7.7e-89 297.6 4.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FAD_binding_4 PF01565.18 EME85520.1 - 0.00058 19.3 0.5 0.0075 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DUF4293 PF14126.1 EME85520.1 - 0.32 10.9 4.0 14 5.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) Mit_proteolip PF08039.6 EME85520.1 - 0.89 9.5 5.5 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial proteolipid DUF1043 PF06295.7 EME85520.1 - 1.8 8.1 4.1 0.78 9.3 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Wzy_C PF04932.10 EME85520.1 - 2.6 7.8 11.1 0.56 9.9 0.7 2.9 2 2 0 2 2 2 0 O-Antigen ligase PrgI PF12666.2 EME85520.1 - 2.6 8.2 19.8 0.39 10.8 0.7 4.0 4 0 0 4 4 4 0 PrgI family protein Cu-oxidase_2 PF07731.9 EME85521.1 - 1.3e-47 160.7 10.5 2.4e-42 143.7 1.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EME85521.1 - 1.6e-42 143.9 9.1 1.1e-39 134.8 1.0 4.2 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EME85521.1 - 1.3e-41 142.1 2.6 3.6e-35 121.2 0.2 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.1 EME85521.1 - 0.0004 20.2 0.0 5.4 6.9 0.0 3.9 4 1 0 4 4 4 1 Cupredoxin-like domain DUF2846 PF11008.3 EME85521.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) OMPdecase PF00215.19 EME85522.1 - 1.9e-76 256.4 0.0 2.2e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF4601 PF15373.1 EME85522.1 - 0.098 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) F-box PF00646.28 EME85524.1 - 1.3e-07 31.0 0.3 3e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME85524.1 - 1.4e-05 24.7 0.0 9.1e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like Dus PF01207.12 EME85525.1 - 2.7e-56 190.6 0.0 1.1e-55 188.6 0.0 2.0 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EME85525.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CBM_10 PF02013.11 EME85526.1 - 0.056 13.7 3.7 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Cellulose or protein binding domain NAD_binding_6 PF08030.7 EME85527.1 - 1.1e-17 64.4 0.1 1.9e-12 47.3 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME85527.1 - 1.2e-17 64.1 7.0 4.7e-17 62.2 4.8 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME85527.1 - 4.1e-10 39.4 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EME85527.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Transport_MerF PF11431.3 EME85527.1 - 0.51 10.0 6.4 0.67 9.6 1.2 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF AMP-binding PF00501.23 EME85528.1 - 3.7e-56 190.3 4.7 6.6e-22 77.4 0.0 4.9 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EME85528.1 - 7.2e-13 49.1 0.2 7.2e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 EME85528.1 - 0.00044 19.9 0.3 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 Gas vesicle protein G DUF3455 PF11937.3 EME85530.1 - 5.4e-41 140.4 0.6 6e-41 140.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Peptidase_C69 PF03577.10 EME85535.1 - 4.3e-21 75.2 0.1 9.2e-21 74.1 0.1 1.5 1 1 0 1 1 1 1 Peptidase family C69 Trypsin PF00089.21 EME85536.1 - 3.4e-12 46.4 0.0 5.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EME85536.1 - 9.6e-05 22.3 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain F-box-like PF12937.2 EME85537.1 - 8.5e-07 28.6 0.1 2e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME85537.1 - 8.1e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain FMN_dh PF01070.13 EME85538.1 - 2.1e-80 270.2 1.9 1.8e-77 260.6 1.3 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EME85538.1 - 0.00022 20.2 0.2 0.0019 17.1 0.1 2.0 1 1 1 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EME85538.1 - 0.0004 19.4 1.4 0.02 13.8 0.0 2.8 2 1 1 3 3 3 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 EME85538.1 - 0.00055 18.9 0.8 0.0019 17.1 0.3 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Ribul_P_3_epim PF00834.14 EME85538.1 - 0.0046 16.0 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.16 EME85538.1 - 0.0079 15.4 0.0 0.094 11.9 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF2372 PF10178.4 EME85539.1 - 0.001 19.1 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) HA2 PF04408.18 EME85540.1 - 1.1e-17 63.9 0.0 3.9e-17 62.1 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME85540.1 - 8.2e-13 48.0 0.1 5.4e-12 45.3 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EME85540.1 - 1.9e-09 37.3 0.1 5.3e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EME85540.1 - 5.9e-09 35.6 0.2 1.7e-08 34.1 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME85540.1 - 0.00018 21.6 0.2 0.0013 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EME85540.1 - 0.0014 17.6 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EME85540.1 - 0.014 14.9 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.10 EME85540.1 - 0.029 14.1 0.1 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EME85540.1 - 0.031 14.0 0.3 0.11 12.3 0.2 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EME85540.1 - 0.64 10.3 0.0 0.64 10.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain adh_short_C2 PF13561.1 EME85544.1 - 1.7e-23 83.6 0.7 2e-23 83.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME85544.1 - 2.1e-15 57.0 3.7 3.2e-15 56.4 2.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_18 PF12847.2 EME85544.1 - 0.041 14.4 0.4 0.099 13.2 0.2 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L21e PF01157.13 EME85544.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L21e Herpes_Helicase PF02689.9 EME85545.1 - 3.9e-09 34.8 0.0 5.1e-09 34.4 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EME85545.1 - 2.1e-08 34.2 0.0 5.1e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EME85545.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EME85545.1 - 0.014 14.3 0.2 0.02 13.8 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase DCX PF03607.12 EME85545.1 - 0.067 12.7 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Doublecortin Na_H_Exchanger PF00999.16 EME85546.1 - 1.4e-40 139.0 13.2 1.8e-40 138.6 9.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DER1 PF04511.10 EME85546.1 - 0.023 14.2 0.6 0.14 11.6 0.0 2.4 3 0 0 3 3 3 0 Der1-like family DUF1049 PF06305.6 EME85546.1 - 6.2 6.3 7.3 8 6.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) ALO PF04030.9 EME85548.1 - 1.8e-80 270.2 0.8 1.8e-80 270.2 0.6 1.5 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EME85548.1 - 7.8e-30 103.1 0.0 1.3e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3112 PF11309.3 EME85549.1 - 9.6e-42 142.4 11.3 1.7e-40 138.4 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) PalH PF08733.5 EME85549.1 - 0.26 10.0 0.0 0.26 10.0 0.0 2.4 2 1 0 2 2 2 0 PalH/RIM21 CcoS PF03597.10 EME85549.1 - 6 6.4 10.1 0.17 11.3 0.2 3.3 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type Zn_clus PF00172.13 EME85550.1 - 0.0042 16.9 9.2 0.0076 16.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlaF PF07309.6 EME85550.1 - 0.019 14.8 0.1 0.045 13.6 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF BP28CT PF08146.7 EME85551.1 - 2.1e-32 111.9 3.9 6.3e-32 110.4 2.7 1.9 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EME85551.1 - 2e-18 66.4 2.8 2e-18 66.4 1.9 3.7 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EME85551.1 - 0.00043 20.1 9.9 0.041 13.9 0.2 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EME85551.1 - 0.0026 18.1 10.8 0.025 15.0 0.2 6.0 5 0 0 5 5 5 1 HEAT-like repeat NRDE-2 PF08424.5 EME85552.1 - 4.5e-66 222.9 0.1 4.5e-66 222.9 0.0 2.2 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_8 PF13181.1 EME85552.1 - 0.064 13.0 0.1 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EME85553.1 - 5.1e-08 32.3 0.0 7.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HeLo PF14479.1 EME85553.1 - 2e-07 30.9 0.1 3.8e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EME85553.1 - 0.00094 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EME85554.1 - 1.8e-21 76.4 0.0 2.8e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME85554.1 - 3e-13 49.4 0.0 4.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EME85554.1 - 0.0086 15.1 0.2 0.019 14.0 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Patatin PF01734.17 EME85555.1 - 1.1e-14 54.9 0.0 3.3e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase F-box-like PF12937.2 EME85556.1 - 8.4e-05 22.2 0.2 0.00027 20.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME85556.1 - 0.034 13.8 0.1 0.2 11.3 0.1 2.4 1 1 0 1 1 1 0 F-box domain FeoB_C PF07664.7 EME85556.1 - 0.33 10.4 1.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus adh_short_C2 PF13561.1 EME85557.1 - 5.5e-26 91.8 0.0 6.4e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME85557.1 - 2.6e-23 82.7 1.8 4.1e-23 82.1 1.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME85557.1 - 1.7e-07 31.0 1.2 4.5e-07 29.6 0.7 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EME85557.1 - 0.005 16.3 0.1 0.37 10.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Cyt-b5 PF00173.23 EME85560.1 - 1.8e-05 24.4 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1612 PF07756.7 EME85561.1 - 0.017 15.2 0.2 6.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) EF-hand_1 PF00036.27 EME85562.1 - 5.3e-38 125.4 12.1 2e-09 36.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EME85562.1 - 2.2e-33 114.2 6.1 1.9e-18 66.3 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EME85562.1 - 1.2e-29 99.5 8.5 1.1e-08 34.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EME85562.1 - 2.4e-29 100.7 12.7 4.7e-14 51.7 0.4 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EME85562.1 - 1.5e-25 87.3 11.9 2.1e-07 29.9 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EME85562.1 - 2e-18 66.0 0.3 3.6e-08 33.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EME85562.1 - 4.2e-10 39.6 0.1 0.00058 19.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EME85562.1 - 2.3e-08 33.7 2.4 0.00099 18.8 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EME85562.1 - 0.00043 19.8 0.0 0.72 9.3 0.0 2.4 2 1 0 2 2 2 2 Caleosin related protein UPF0154 PF03672.8 EME85562.1 - 0.00058 19.4 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 EME85562.1 - 0.0012 18.5 1.3 0.77 9.4 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB EF-hand_10 PF14788.1 EME85562.1 - 0.0068 16.0 2.1 0.43 10.2 0.1 2.7 2 1 1 3 3 3 1 EF hand PMBR PF09373.5 EME85562.1 - 0.016 15.1 0.1 3.7 7.6 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat EF-hand_2 PF09068.6 EME85562.1 - 0.022 14.8 0.0 0.068 13.2 0.0 1.9 2 1 0 2 2 1 0 EF hand SAP PF02037.22 EME85562.1 - 0.024 14.1 0.0 1.2 8.7 0.0 2.8 2 1 1 3 3 3 0 SAP domain DUF1456 PF07308.8 EME85562.1 - 0.039 13.9 0.5 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Tenui_NCP PF04876.7 EME85562.1 - 0.053 13.0 0.6 0.56 9.7 0.0 2.2 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein p25-alpha PF05517.7 EME85562.1 - 0.058 13.6 0.5 1.8 8.8 0.2 2.1 1 1 1 2 2 2 0 p25-alpha DUF3349 PF11829.3 EME85562.1 - 0.096 13.1 0.5 7 7.1 0.0 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF592 PF04574.8 EME85562.1 - 0.12 11.9 0.1 4.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF592) TRAP_alpha PF03896.11 EME85563.1 - 0.00037 19.6 0.5 0.0021 17.1 0.3 1.9 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Fungal_trans PF04082.13 EME85565.1 - 7.7e-29 100.3 0.0 1.8e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME85565.1 - 3.6e-07 29.9 9.1 6.8e-07 29.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP12 PF07542.6 EME85566.1 - 9.1e-37 125.7 1.0 9.1e-37 125.7 0.7 1.9 3 0 0 3 3 3 1 ATP12 chaperone protein BEX PF04538.7 EME85567.1 - 1.9 8.7 8.0 4.3 7.5 5.5 1.6 1 1 0 1 1 1 0 Brain expressed X-linked like family GMC_oxred_N PF00732.14 EME85568.1 - 0.0063 15.7 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase ATG27 PF09451.5 EME85569.1 - 3.1e-63 213.5 0.0 4.3e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 SGL PF08450.7 EME85571.1 - 1.9e-22 79.8 0.5 2.8e-22 79.3 0.3 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EME85571.1 - 1.6e-05 24.8 0.0 0.00033 20.6 0.0 2.8 1 1 1 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EME85571.1 - 0.00013 21.8 1.3 0.00037 20.4 0.0 2.3 3 0 0 3 3 3 1 Arylesterase DUF2422 PF10337.4 EME85572.1 - 3.7e-77 260.0 5.3 3.7e-77 260.0 3.7 5.1 3 2 1 4 4 4 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EME85572.1 - 9.4e-14 51.4 11.3 9.4e-14 51.4 7.8 3.3 2 1 2 4 4 4 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EME85572.1 - 1.3e-09 38.0 0.1 4.2e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) Ribosomal_L32e PF01655.13 EME85573.1 - 4.4e-51 171.5 1.4 5.7e-51 171.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L10 PF00466.15 EME85574.1 - 2.7e-17 62.5 0.0 4.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Mis12 PF05859.7 EME85575.1 - 9.6e-35 119.5 0.5 1.2e-34 119.2 0.3 1.1 1 0 0 1 1 1 1 Mis12 protein CbiZ PF01955.13 EME85575.1 - 0.043 13.6 0.4 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Adenosylcobinamide amidohydrolase Abdominal-A PF12407.3 EME85575.1 - 0.048 13.1 1.0 0.14 11.6 0.7 1.8 1 0 0 1 1 1 0 Homeobox protein Glyco_hydro_12 PF01670.11 EME85576.1 - 3.9e-30 104.6 2.6 7.2e-30 103.8 1.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PPV_E2_C PF00511.12 EME85576.1 - 3.6 7.5 15.5 0.93 9.4 1.9 2.8 2 1 1 3 3 3 0 E2 (early) protein, C terminal Abhydrolase_6 PF12697.2 EME85579.1 - 0.035 13.9 0.1 0.064 13.1 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3317 PF11779.3 EME85580.1 - 1.6e-21 75.4 2.0 1.9e-21 75.2 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) CRT10 PF08728.5 EME85581.1 - 8.7e-10 37.2 0.0 8.8e-10 37.2 0.0 1.1 1 0 0 1 1 1 1 CRT10 DUF1640 PF07798.6 EME85583.1 - 2e-12 47.5 5.8 2e-12 47.5 4.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DUF4407 PF14362.1 EME85583.1 - 0.26 10.2 13.6 0.21 10.4 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) IncA PF04156.9 EME85583.1 - 1.5 8.4 9.6 0.17 11.4 3.2 2.0 2 0 0 2 2 2 0 IncA protein PQ-loop PF04193.9 EME85584.1 - 9.9e-23 79.4 7.4 1.7e-18 65.9 0.7 2.7 2 1 0 2 2 2 2 PQ loop repeat Oxidored_q2 PF00420.19 EME85584.1 - 0.079 12.5 0.3 0.079 12.5 0.2 2.5 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SUR7 PF06687.7 EME85584.1 - 0.094 12.2 4.0 0.2 11.2 2.8 1.7 1 1 0 1 1 1 0 SUR7/PalI family MtN3_slv PF03083.11 EME85584.1 - 0.93 9.4 10.8 0.25 11.2 1.0 3.5 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange DUF805 PF05656.9 EME85584.1 - 7.6 6.3 13.0 3 7.6 7.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Peptidase_M24 PF00557.19 EME85585.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 ER_lumen_recept PF00810.13 EME85586.1 - 2.3e-55 187.1 0.9 3.9e-55 186.3 0.6 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EME85586.1 - 0.027 14.0 5.4 3.4 7.2 0.2 3.9 3 1 1 4 4 4 0 PQ loop repeat MgtE_N PF03448.12 EME85587.1 - 0.017 15.4 3.0 0.37 11.1 0.4 2.9 2 0 0 2 2 2 0 MgtE intracellular N domain DUF445 PF04286.7 EME85587.1 - 0.65 9.4 14.2 0.55 9.7 7.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF445) LamB_YcsF PF03746.11 EME85588.1 - 4.7e-70 235.4 0.0 5.5e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Abhydrolase_4 PF08386.5 EME85588.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AHS2 PF02626.10 EME85589.1 - 5e-75 252.2 0.0 7.6e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EME85589.1 - 2.3e-54 183.8 0.0 4.4e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EME85589.1 - 2.9e-35 120.6 0.1 6.7e-35 119.5 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 EME85589.1 - 2.3e-31 108.8 0.0 4.5e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 EME85589.1 - 5.8e-29 100.2 0.0 1.3e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EME85589.1 - 6.6e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME85589.1 - 1.7e-08 33.6 0.0 2.5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EME85589.1 - 6.3e-06 25.7 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 EME85589.1 - 3.9e-05 23.2 1.3 0.00023 20.7 0.8 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.17 EME85589.1 - 0.028 13.7 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EME85589.1 - 0.055 12.9 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF3431 PF11913.3 EME85591.1 - 3.6e-07 29.8 0.0 5.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Hist_deacetyl PF00850.14 EME85592.1 - 4.5e-89 298.7 0.4 6.5e-89 298.2 0.3 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EME85592.1 - 8.6e-38 129.5 0.0 1.3e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain DUF3431 PF11913.3 EME85592.1 - 0.03 13.7 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) Abhydrolase_5 PF12695.2 EME85592.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family BTB PF00651.26 EME85593.1 - 6.2e-05 22.9 0.0 7.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Arm PF00514.18 EME85594.1 - 5.4e-08 32.3 8.0 0.0083 15.9 0.1 7.3 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EME85594.1 - 0.018 15.0 9.9 11 6.4 0.0 6.2 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.1 EME85594.1 - 0.037 14.3 10.0 0.97 9.7 0.1 5.0 5 1 0 5 5 5 0 HEAT repeats TIP49 PF06068.8 EME85595.1 - 3.5e-173 575.9 0.8 4.1e-173 575.6 0.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EME85595.1 - 8.1e-08 31.6 0.2 0.00053 19.1 0.0 2.6 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EME85595.1 - 6.6e-07 29.5 0.2 0.0031 17.7 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EME85595.1 - 8.7e-05 21.5 0.2 0.00015 20.7 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EME85595.1 - 0.00028 20.9 0.0 0.0023 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME85595.1 - 0.0011 19.1 0.3 0.19 11.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME85595.1 - 0.0018 18.1 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EME85595.1 - 0.0029 16.8 0.5 0.07 12.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EME85595.1 - 0.039 13.4 0.1 9.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EME85595.1 - 0.04 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EME85595.1 - 0.11 12.2 0.2 20 4.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) FDF PF09532.5 EME85597.1 - 1.3e-17 64.2 0.9 4.1e-17 62.6 0.6 1.9 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.2 EME85597.1 - 1.4e-16 60.0 2.4 4e-11 42.5 0.0 2.8 1 1 1 2 2 2 2 Scd6-like Sm domain Sec2p PF06428.6 EME85598.1 - 3.6e-10 39.5 14.7 3.6e-10 39.5 10.2 2.4 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Tup_N PF08581.5 EME85598.1 - 0.01 16.0 9.7 1 9.6 2.5 2.9 2 1 0 2 2 2 0 Tup N-terminal Tropomyosin PF00261.15 EME85598.1 - 0.014 14.4 0.9 0.014 14.4 0.6 2.9 2 1 0 2 2 2 0 Tropomyosin Phage_GPO PF05929.6 EME85598.1 - 0.054 12.7 12.7 0.15 11.3 5.1 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.1 EME85598.1 - 0.071 12.2 20.5 1.4 8.0 0.2 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EME85598.1 - 0.095 12.2 21.0 1.3 8.6 0.3 3.0 2 1 1 3 3 3 0 IncA protein HrpA_pilin PF09589.5 EME85598.1 - 0.14 12.6 5.6 0.31 11.4 3.9 1.8 1 1 0 1 1 1 0 HrpA pilus formation protein DUF812 PF05667.6 EME85598.1 - 0.21 10.0 14.5 0.32 9.4 10.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.4 EME85598.1 - 1 7.5 15.1 1.7 6.8 10.5 1.3 1 1 0 1 1 1 0 Transmembrane protein Orbi_VP5 PF00901.12 EME85598.1 - 1 7.4 15.3 0.11 10.7 7.1 1.7 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 ATG16 PF08614.6 EME85598.1 - 1.1 9.0 21.1 0.74 9.6 0.3 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EME85598.1 - 1.2 9.5 21.0 0.51 10.7 1.1 4.2 2 2 1 3 3 3 0 SlyX Syntaxin_2 PF14523.1 EME85598.1 - 1.5 8.9 11.3 0.21 11.6 3.6 2.4 2 1 1 3 3 3 0 Syntaxin-like protein DUF1640 PF07798.6 EME85598.1 - 1.9 8.5 13.1 0.26 11.2 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) HAUS6_N PF14661.1 EME85598.1 - 1.9 7.7 17.2 1.2 8.3 6.5 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TBPIP PF07106.8 EME85598.1 - 1.9 7.9 16.3 8.3 5.9 0.1 2.7 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EME85598.1 - 2.7 6.5 17.2 0.69 8.5 6.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Methyltransf_14 PF08484.6 EME85598.1 - 3.7 7.0 8.8 1.1 8.8 0.2 2.9 3 0 0 3 3 3 0 C-methyltransferase C-terminal domain YjcZ PF13990.1 EME85598.1 - 4.9 6.1 11.8 6 5.9 4.7 2.0 2 0 0 2 2 2 0 YjcZ-like protein APG6 PF04111.7 EME85598.1 - 5.1 6.0 22.8 3.5 6.5 0.5 2.7 2 1 1 3 3 3 0 Autophagy protein Apg6 TSC22 PF01166.13 EME85598.1 - 5.5 7.0 15.7 1.3 9.0 1.5 4.1 2 2 2 4 4 4 0 TSC-22/dip/bun family DUF972 PF06156.8 EME85598.1 - 5.6 7.3 17.2 23 5.3 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EME85598.1 - 7.7 4.8 12.6 0.98 7.7 4.5 1.9 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.16 EME85599.1 - 1.8e-12 47.0 10.2 1.9e-12 46.9 7.1 1.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME85599.1 - 7.2e-11 41.7 9.6 9.5e-11 41.3 6.6 1.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME85599.1 - 2e-06 28.0 6.4 2.3e-06 27.8 4.4 1.1 1 0 0 1 1 1 1 bZIP Maf transcription factor MAT1 PF06391.8 EME85599.1 - 0.068 12.7 3.9 0.072 12.6 2.7 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 HALZ PF02183.13 EME85599.1 - 0.14 11.8 1.9 0.43 10.3 0.2 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper GBP_C PF02841.9 EME85599.1 - 0.55 9.3 4.2 0.61 9.2 2.9 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain PIN_4 PF13638.1 EME85599.1 - 0.57 10.2 2.2 0.58 10.2 1.5 1.1 1 0 0 1 1 1 0 PIN domain DUF3020 PF11223.3 EME85599.1 - 0.72 10.3 6.8 0.18 12.2 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3020) DUF3886 PF13025.1 EME85599.1 - 4.6 7.2 8.1 1.8 8.5 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Lactamase_B PF00753.22 EME85602.1 - 5.1e-29 101.3 4.2 7.9e-29 100.6 2.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME85602.1 - 1.4e-05 24.7 0.2 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EME85602.1 - 0.0026 17.0 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peripla_BP_4 PF13407.1 EME85602.1 - 0.0093 15.3 0.2 0.021 14.2 0.1 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain GTP_EFTU PF00009.22 EME85603.1 - 2.7e-22 79.1 0.1 1.9e-21 76.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME85603.1 - 5.9e-14 52.0 0.1 1.4e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME85603.1 - 2.1e-11 43.7 2.9 2.7e-10 40.2 1.5 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EME85603.1 - 0.0012 18.3 0.9 0.41 10.1 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EME85603.1 - 0.0027 18.1 0.3 0.14 12.6 0.2 3.1 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EME85603.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EME85603.1 - 0.038 13.6 0.2 0.15 11.7 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu domain 4 MobB PF03205.9 EME85603.1 - 0.072 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mid2 PF04478.7 EME85605.1 - 0.049 13.0 0.8 0.089 12.2 0.5 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RCR PF12273.3 EME85605.1 - 0.79 10.2 3.1 1.7 9.1 2.2 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Abhydrolase_3 PF07859.8 EME85606.1 - 1e-57 195.1 0.1 1.4e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EME85606.1 - 5.5e-10 38.4 0.0 7e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EME85606.1 - 1.4e-05 24.4 0.0 0.0092 15.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME85606.1 - 0.00021 21.0 0.0 0.00061 19.5 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EME85606.1 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain MFS_1 PF07690.11 EME85607.1 - 4.8e-26 91.3 44.1 9.3e-25 87.0 21.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 EME85608.1 - 2.6e-57 192.9 14.0 3.2e-57 192.6 9.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein Voltage_CLC PF00654.15 EME85608.1 - 0.003 16.6 4.4 0.0042 16.1 2.9 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel QueT PF06177.6 EME85608.1 - 0.017 15.1 1.7 0.023 14.6 0.1 1.8 2 0 0 2 2 2 0 QueT transporter HSP70 PF00012.15 EME85609.1 - 0.0003 18.8 0.5 0.00058 17.8 0.0 1.6 2 0 0 2 2 2 1 Hsp70 protein Methyltransf_23 PF13489.1 EME85609.1 - 0.0015 18.2 0.0 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_M22 PF00814.20 EME85609.1 - 0.098 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycoprotease family Methyltransf_18 PF12847.2 EME85609.1 - 0.11 13.0 0.2 0.42 11.1 0.1 2.1 1 0 0 1 1 1 0 Methyltransferase domain IncA PF04156.9 EME85609.1 - 0.28 10.7 2.5 0.58 9.7 1.8 1.5 1 0 0 1 1 1 0 IncA protein DUF2890 PF11081.3 EME85610.1 - 0.098 12.7 6.7 0.13 12.3 3.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EME85610.1 - 0.32 8.9 2.9 0.47 8.4 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4632 PF15451.1 EME85610.1 - 0.95 9.4 4.3 2.4 8.1 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Coprogen_oxidas PF01218.13 EME85611.1 - 1.1e-138 460.7 0.1 1.3e-138 460.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PMT PF02366.13 EME85612.1 - 2.8e-84 282.3 17.1 2.8e-84 282.3 11.9 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EME85612.1 - 4.9e-37 127.3 0.4 6.8e-37 126.8 0.3 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 EME85612.1 - 0.59 9.6 3.1 2.5 7.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) SWIM PF04434.12 EME85613.1 - 0.00045 19.6 0.1 0.00075 18.9 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger MitMem_reg PF13012.1 EME85614.1 - 2.9e-38 130.5 0.1 8.5e-38 128.9 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EME85614.1 - 2.8e-28 97.9 0.1 1.5e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mak10 PF04112.8 EME85614.1 - 0.036 13.2 0.1 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase HD PF01966.17 EME85615.1 - 3.8e-09 36.5 0.1 1.4e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 HD domain Ras PF00071.17 EME85616.1 - 7.3e-11 41.7 0.1 1.1e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EME85616.1 - 6e-05 23.5 0.4 0.089 13.2 0.0 2.4 1 1 1 2 2 2 2 Miro-like protein Pex16 PF08610.5 EME85617.1 - 4.7e-95 318.4 0.0 5.4e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Atg8 PF02991.11 EME85618.1 - 2.6e-51 171.9 0.2 3.1e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EME85618.1 - 2.6e-06 27.5 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2665 PF11654.3 EME85619.1 - 2.1e-08 33.6 0.0 2.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) Colicin_Ia PF11504.3 EME85619.1 - 0.13 12.1 0.3 0.23 11.3 0.1 1.5 1 1 1 2 2 2 0 Colicin Ia TatD_DNase PF01026.16 EME85621.1 - 5.7e-31 107.6 0.0 7.4e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase peroxidase PF00141.18 EME85623.1 - 2.4e-28 99.2 0.0 3.6e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Yip1 PF04893.12 EME85624.1 - 4.4e-13 49.0 14.4 6.3e-13 48.5 10.0 1.2 1 0 0 1 1 1 1 Yip1 domain GTP_EFTU PF00009.22 EME85625.1 - 3.7e-32 111.2 2.5 2.1e-31 108.8 0.0 3.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EME85625.1 - 7.5e-21 74.0 0.0 2.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EME85625.1 - 1.4e-10 41.1 4.5 7.3e-10 38.8 0.2 3.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME85625.1 - 7.5e-06 25.8 2.1 1.6e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EME85625.1 - 0.0021 17.6 0.0 0.0097 15.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 EME85625.1 - 0.015 14.9 0.2 0.075 12.6 0.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu domain 4 AAA_22 PF13401.1 EME85625.1 - 0.016 15.3 0.0 0.074 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME85625.1 - 0.025 14.5 0.0 0.025 14.5 0.0 3.1 2 1 0 3 3 3 0 AAA ATPase domain RNA12 PF10443.4 EME85626.1 - 1e-166 554.7 0.0 1.4e-166 554.2 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EME85626.1 - 6.6e-07 29.2 0.0 2.5e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EME85626.1 - 0.00017 21.1 0.0 0.00047 19.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EME85626.1 - 0.00033 20.6 0.6 0.0027 17.7 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain RRM_6 PF14259.1 EME85626.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EME85626.1 - 0.015 15.1 0.0 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) RRM_5 PF13893.1 EME85626.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 EME85628.1 - 5.5e-272 903.0 5.0 6.3e-272 902.8 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME85628.1 - 8.1e-17 60.7 0.0 1.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EME85628.1 - 0.0023 17.1 0.1 0.023 13.8 0.0 2.2 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EME85628.1 - 0.0023 17.5 0.0 0.0055 16.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EME85628.1 - 0.26 11.1 3.6 21 4.9 2.5 3.1 1 1 0 1 1 1 0 Cell division protein FtsA PMBR PF09373.5 EME85628.1 - 0.31 11.0 1.2 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Pseudomurein-binding repeat DUF1843 PF08898.5 EME85628.1 - 2.8 8.0 6.2 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) CFEM PF05730.6 EME85631.1 - 2.6e-06 27.1 10.7 4.6e-06 26.3 7.4 1.4 1 0 0 1 1 1 1 CFEM domain Menin PF05053.8 EME85631.1 - 0.53 8.3 2.6 0.86 7.6 1.8 1.3 1 0 0 1 1 1 0 Menin EamA PF00892.15 EME85631.1 - 3.1 7.8 12.1 5 7.1 2.8 3.1 3 0 0 3 3 3 0 EamA-like transporter family Glu_synthase PF01645.12 EME85632.1 - 1.1e-158 527.9 0.0 1.7e-158 527.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EME85632.1 - 1.4e-139 464.8 0.0 2.1e-139 464.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EME85632.1 - 7.1e-121 402.8 0.0 1.5e-120 401.8 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EME85632.1 - 2e-66 222.8 2.1 3.7e-66 221.9 1.4 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EME85632.1 - 3.9e-22 77.9 0.0 9.4e-22 76.7 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EME85632.1 - 1.5e-16 60.8 0.0 6.1e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME85632.1 - 1.6e-12 47.9 0.1 7.8e-05 22.8 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME85632.1 - 3.7e-09 36.4 0.0 1.4e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME85632.1 - 4e-07 29.4 0.0 6.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EME85632.1 - 1.3e-06 28.6 0.2 0.00018 21.8 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME85632.1 - 6.1e-06 25.3 0.2 5.5e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME85632.1 - 2.4e-05 23.0 0.1 2.4e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EME85632.1 - 9.2e-05 21.4 0.8 0.00045 19.1 0.1 2.3 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EME85632.1 - 0.0004 19.5 0.2 0.0017 17.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EME85632.1 - 0.00098 19.3 1.6 0.82 9.9 0.0 3.5 4 0 0 4 4 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EME85632.1 - 0.0025 16.9 0.1 0.0025 16.9 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EME85632.1 - 0.0046 16.0 0.0 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 EME85632.1 - 0.01 14.0 0.2 0.18 9.9 0.0 2.3 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.16 EME85632.1 - 0.012 15.4 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.11 EME85632.1 - 0.024 14.1 0.2 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EME85632.1 - 0.03 13.1 0.2 0.21 10.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EME85632.1 - 0.031 13.8 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EME85632.1 - 0.031 14.0 0.1 0.14 11.9 0.0 2.1 2 1 0 3 3 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EME85632.1 - 0.032 14.3 0.2 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME85632.1 - 0.038 13.7 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Acid_phosphat_B PF03767.9 EME85632.1 - 0.04 13.2 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) 2-Hacid_dh_C PF02826.14 EME85632.1 - 0.049 12.7 0.2 0.21 10.7 0.0 2.1 3 0 0 3 3 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EME85632.1 - 0.058 13.2 0.1 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME85632.1 - 0.19 12.1 0.7 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.7 EME85632.1 - 0.34 9.7 0.1 1.1 8.0 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EME85632.1 - 0.88 9.1 2.4 0.43 10.1 0.0 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_P2_GpE PF06528.7 EME85633.1 - 0.041 13.3 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage P2 GpE WD40 PF00400.27 EME85634.1 - 1.3e-23 81.9 4.0 1.1e-06 28.3 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 EME85634.1 - 5.9e-08 32.5 2.5 5.9e-08 32.5 1.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) PD40 PF07676.7 EME85634.1 - 0.011 15.4 0.0 3.1 7.5 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EME85634.1 - 0.014 15.1 0.0 0.34 10.5 0.0 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 EME85634.1 - 0.015 15.0 0.5 0.039 13.7 0.3 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal DUF3312 PF11768.3 EME85634.1 - 0.025 12.8 0.0 0.05 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DPPIV_N PF00930.16 EME85634.1 - 0.096 11.2 0.0 2.7 6.4 0.0 2.7 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region MRJP PF03022.11 EME85634.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein DUF3128 PF11326.3 EME85635.1 - 1.4e-29 102.0 4.1 2.4e-29 101.2 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Nucleoporin_FG PF13634.1 EME85635.1 - 0.04 14.1 0.3 0.071 13.3 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region EF-hand_4 PF12763.2 EME85636.1 - 2.1e-33 114.1 0.0 4.6e-14 52.0 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EME85636.1 - 2.4e-10 40.3 0.0 0.0037 17.3 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EME85636.1 - 3.7e-07 28.9 0.3 1 8.8 0.0 5.5 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 EME85636.1 - 1.2e-06 27.9 0.0 0.74 9.4 0.0 4.6 4 1 1 5 5 5 2 EF-hand domain pair UBA PF00627.26 EME85636.1 - 5.9e-06 25.9 0.0 1.4e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Acetyltransf_7 PF13508.1 EME85636.1 - 3.6e-05 23.8 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Macoilin PF09726.4 EME85636.1 - 0.00011 20.6 14.9 0.00011 20.6 10.4 2.2 2 0 0 2 2 1 1 Transmembrane protein Acetyltransf_1 PF00583.19 EME85636.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EF-hand_6 PF13405.1 EME85636.1 - 0.0051 16.5 1.1 13 5.9 0.1 4.7 5 0 0 5 5 5 0 EF-hand domain Acetyltransf_CG PF14542.1 EME85636.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EME85636.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IncA PF04156.9 EME85636.1 - 0.02 14.4 37.6 0.13 11.8 18.1 2.2 1 1 1 2 2 2 0 IncA protein Acetyltransf_10 PF13673.1 EME85636.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MAD PF05557.8 EME85636.1 - 0.27 9.2 27.4 0.41 8.6 19.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Erp_C PF06780.6 EME85636.1 - 2.8 7.7 7.1 1 9.2 2.3 1.9 1 1 1 2 2 2 0 Erp protein C-terminus CENP-F_leu_zip PF10473.4 EME85636.1 - 5.6 6.8 35.0 0.28 11.0 11.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EME85636.1 - 9.2 6.0 38.2 3.4 7.4 15.2 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Glyco_hydro_43 PF04616.9 EME85637.1 - 1e-22 80.6 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Rad51 PF08423.6 EME85638.1 - 7.5e-26 90.5 0.0 9.4e-25 86.9 0.0 2.0 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 EME85638.1 - 4.2e-13 49.1 0.2 6.9e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EME85638.1 - 6e-05 22.2 0.4 0.0082 15.2 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 EME85638.1 - 0.00026 20.1 0.1 0.00096 18.3 0.1 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EME85638.1 - 0.021 13.7 0.1 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Carn_acyltransf PF00755.15 EME85639.1 - 6.8e-165 549.5 0.0 4e-151 504.0 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Sec16_C PF12931.2 EME85640.1 - 3.3e-80 269.8 0.1 4.8e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EME85640.1 - 1.2e-24 86.5 0.0 3.2e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 EME85641.1 - 1.2e-20 73.5 0.0 2.6e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EME85641.1 - 3e-15 57.2 0.1 2.7e-14 54.1 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME85641.1 - 7e-09 36.1 0.0 2.2e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME85641.1 - 9.8e-07 28.6 0.0 3.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME85641.1 - 0.0018 17.9 0.1 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SKN1 PF03935.10 EME85643.1 - 2e-217 722.3 7.4 2.4e-217 722.0 5.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DNA_pol_viral_N PF00242.12 EME85643.1 - 0.072 12.1 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Methyltransf_31 PF13847.1 EME85644.1 - 2.7e-22 78.9 0.0 3.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME85644.1 - 2.7e-21 75.8 0.1 7.2e-21 74.4 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME85644.1 - 3.4e-18 65.6 0.0 4.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME85644.1 - 1.5e-14 54.1 0.1 2.9e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME85644.1 - 4.5e-12 46.3 0.0 7.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME85644.1 - 2.5e-11 44.1 0.0 4.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME85644.1 - 2.8e-11 43.0 0.1 9.6e-11 41.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EME85644.1 - 1.6e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME85644.1 - 7.3e-08 32.4 0.3 4.3e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EME85644.1 - 7e-07 28.9 0.1 1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EME85644.1 - 1.6e-05 24.0 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 EME85644.1 - 4.9e-05 22.8 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FmrO PF07091.6 EME85644.1 - 0.00088 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DUF938 PF06080.7 EME85644.1 - 0.004 16.7 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GCD14 PF08704.5 EME85644.1 - 0.0046 16.5 0.1 0.0064 16.0 0.1 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.1 EME85644.1 - 0.0054 16.4 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.3 EME85644.1 - 0.0055 15.6 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EME85644.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EME85644.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.11 EME85644.1 - 0.022 13.1 0.1 0.032 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EME85644.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EME85644.1 - 0.05 12.6 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.10 EME85644.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HTH_Tnp_ISL3 PF13542.1 EME85645.1 - 0.006 15.7 0.2 0.39 9.9 0.0 2.8 2 1 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 GntR PF00392.16 EME85645.1 - 0.078 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Lung_7-TM_R PF06814.8 EME85646.1 - 8.6e-67 225.1 24.4 1e-66 224.8 16.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4112 PF13430.1 EME85647.1 - 2.1e-33 114.3 0.1 2.8e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Abhydrolase_3 PF07859.8 EME85648.1 - 3.2e-62 209.8 0.0 4e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME85648.1 - 1.5e-06 27.2 1.0 2.9e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 EME85648.1 - 1.6e-06 27.4 0.0 3.2e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EME85648.1 - 1.7e-05 23.8 0.0 2.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2424 PF10340.4 EME85648.1 - 2e-05 23.4 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase PF07224.6 EME85648.1 - 0.00041 19.2 0.0 0.00054 18.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.2 EME85648.1 - 0.00045 19.9 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME85648.1 - 0.0026 17.2 0.6 0.014 14.8 0.3 2.0 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EME85648.1 - 0.044 13.0 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Thioesterase PF00975.15 EME85648.1 - 0.09 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UNC-93 PF05978.11 EME85649.1 - 6.1e-13 48.5 5.9 6.1e-13 48.5 4.1 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EME85649.1 - 2.9e-07 29.5 39.9 1.4e-06 27.2 27.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Cullin_binding PF03556.10 EME85650.1 - 0.012 15.7 0.2 0.033 14.3 0.2 1.8 1 0 0 1 1 1 0 Cullin binding DUF948 PF06103.6 EME85650.1 - 0.71 9.7 5.2 18 5.2 0.1 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.22 EME85651.1 - 1.9e-57 190.9 2.2 2e-19 69.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_26 PF13659.1 EME85651.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EME85652.1 - 5.7e-15 54.5 0.2 3e-10 39.5 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Herpes_UL37_1 PF03970.8 EME85652.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein RA PF00788.18 EME85653.1 - 3.2e-15 56.3 0.0 5.8e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EME85653.1 - 7.4e-12 44.9 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EME85653.1 - 8.5e-11 41.8 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EME85653.1 - 0.043 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF972 PF06156.8 EME85653.1 - 0.097 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) WD40 PF00400.27 EME85654.1 - 1e-19 69.5 18.9 5e-10 38.8 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EME85654.1 - 2.5e-13 49.7 0.0 5.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex TFIIE-A_C-term PF11521.3 EME85654.1 - 8.3 6.4 10.1 13 5.8 0.5 2.6 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ras PF00071.17 EME85657.1 - 8.6e-32 109.7 0.2 1e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME85657.1 - 5.8e-21 75.1 0.1 3.4e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME85657.1 - 3.1e-07 29.8 0.1 3.6e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME85657.1 - 9.9e-06 24.8 0.2 1.3e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME85657.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EME85657.1 - 0.036 12.7 2.1 0.12 11.0 0.0 2.4 1 1 1 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.1 EME85658.1 - 0.0044 17.0 0.1 0.026 14.4 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EME85658.1 - 0.0072 16.1 0.0 0.76 9.5 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Baculo_PEP_C PF04513.7 EME85658.1 - 0.017 14.9 0.7 0.093 12.5 0.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MMR_HSR1 PF01926.18 EME85658.1 - 0.028 14.3 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EME85658.1 - 0.07 13.4 0.3 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AIG1 PF04548.11 EME85658.1 - 0.1 11.7 0.2 0.51 9.4 0.1 2.1 2 0 0 2 2 2 0 AIG1 family OHCU_decarbox PF09349.5 EME85660.1 - 3.2e-40 138.0 0.4 3.7e-40 137.8 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase PIG-L PF02585.12 EME85662.1 - 4.9e-26 91.7 0.1 7.6e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase EF-hand_7 PF13499.1 EME85662.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Chs3p PF12271.3 EME85663.1 - 2e-136 453.7 16.7 2.3e-136 453.5 11.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit PGP_phosphatase PF09419.5 EME85665.1 - 1.3e-68 229.6 0.0 1.9e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EME85665.1 - 0.004 16.8 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like LSM PF01423.17 EME85666.1 - 2e-15 56.0 0.6 2.7e-15 55.6 0.4 1.1 1 0 0 1 1 1 1 LSM domain Tail_tube PF10618.4 EME85666.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 Phage tail tube protein SM-ATX PF14438.1 EME85666.1 - 0.04 13.8 0.1 0.065 13.1 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.4 EME85667.1 - 6.2e-11 42.7 9.9 1.2e-10 41.8 4.4 2.7 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 FlaE PF07559.9 EME85668.1 - 0.0047 17.5 4.4 0.0081 16.8 3.0 1.4 1 0 0 1 1 1 1 Flagellar basal body protein FlaE DUF2263 PF10021.4 EME85669.1 - 5.4e-14 52.4 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) TRAPP PF04051.11 EME85670.1 - 4.6e-35 120.3 0.0 5.7e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Las1 PF04031.8 EME85671.1 - 1.9e-43 147.7 0.2 3.2e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Las1-like PTH2 PF01981.11 EME85671.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Ribosomal_L37 PF08561.5 EME85671.1 - 0.18 11.4 3.5 0.43 10.1 2.4 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 NAD_kinase PF01513.16 EME85672.1 - 5.3e-72 241.9 0.0 7.5e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Prominin PF05478.6 EME85672.1 - 0.21 9.0 0.7 0.28 8.6 0.5 1.1 1 0 0 1 1 1 0 Prominin Iso_dh PF00180.15 EME85673.1 - 1.1e-84 284.3 0.0 1.2e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_S24 PF00717.18 EME85674.1 - 1.1e-08 34.5 0.3 8.8e-08 31.6 0.2 2.3 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EME85674.1 - 4.6e-06 26.1 0.0 0.0011 18.4 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 GLTP PF08718.6 EME85675.1 - 4.1e-46 156.7 0.0 5.2e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Methyltransf_10 PF05971.7 EME85676.1 - 1.1e-60 205.2 0.0 1.6e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EME85676.1 - 6.5e-08 32.6 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME85676.1 - 8.3e-08 32.8 0.0 1.8e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME85676.1 - 2.4e-07 30.2 0.0 5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EME85676.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EME85676.1 - 0.00031 20.3 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EME85676.1 - 0.00039 19.6 0.0 0.00072 18.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EME85676.1 - 0.01 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EME85676.1 - 0.023 15.0 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EME85676.1 - 0.033 14.6 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Cyclin_N PF00134.18 EME85678.1 - 0.00013 21.5 0.2 0.0016 18.0 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2011 PF09428.5 EME85680.1 - 2.5e-26 92.1 8.8 4.4e-26 91.2 6.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF2967 PF11179.3 EME85680.1 - 0.2 11.1 10.0 0.37 10.2 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RNase_H2-Ydr279 PF09468.5 EME85680.1 - 3.2 6.8 7.9 4.6 6.3 5.5 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1168 PF06658.7 EME85680.1 - 5.7 6.4 21.0 0.41 10.1 11.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Med19 PF10278.4 EME85680.1 - 9.2 5.8 14.7 60 3.2 9.6 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 EME85680.1 - 9.3 6.0 10.3 16 5.2 7.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Myosin_tail_1 PF01576.14 EME85682.1 - 0.036 11.8 0.1 0.037 11.7 0.1 1.1 1 0 0 1 1 1 0 Myosin tail DivIVA PF05103.8 EME85682.1 - 0.07 13.1 0.4 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 DivIVA protein Ferritin_2 PF13668.1 EME85683.1 - 2.5e-44 150.5 1.2 3.9e-44 149.9 0.8 1.2 1 0 0 1 1 1 1 Ferritin-like domain GPI-anchored PF10342.4 EME85683.1 - 0.093 13.2 0.2 2.7 8.5 0.1 2.4 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF360 PF04020.8 EME85685.1 - 0.021 15.1 5.3 0.021 15.1 3.7 2.1 3 0 0 3 3 3 0 Membrane protein of unknown function MIF PF01187.13 EME85686.1 - 5.9e-13 48.9 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF952 PF06108.7 EME85687.1 - 1.6e-16 59.9 0.0 1.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Dak1 PF02733.12 EME85689.1 - 2.6e-118 394.3 6.2 3.5e-118 393.8 4.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EME85689.1 - 5e-45 153.2 2.7 1.4e-44 151.8 1.0 2.2 2 0 0 2 2 2 1 DAK2 domain LSM PF01423.17 EME85690.1 - 1.9e-17 62.5 0.1 2.5e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EME85690.1 - 0.019 13.5 0.0 0.022 13.3 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein GATA PF00320.22 EME85691.1 - 1.7e-05 24.0 1.0 0.0055 16.0 0.2 2.6 2 0 0 2 2 2 2 GATA zinc finger Tom22 PF04281.8 EME85695.1 - 1.9e-48 163.4 1.9 2.3e-48 163.2 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GFA PF04828.9 EME85696.1 - 1.8e-17 63.0 3.9 2.5e-17 62.5 2.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EME85696.1 - 0.19 11.4 0.4 0.19 11.4 0.3 2.1 2 0 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.6 EME85696.1 - 6 6.4 9.7 3.5 7.2 2.0 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Pro_isomerase PF00160.16 EME85697.1 - 7.3e-47 159.4 0.0 1.7e-46 158.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EME85697.1 - 3e-07 29.9 0.0 7.4e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EME85697.1 - 5.8e-05 22.9 0.1 0.00038 20.3 0.0 2.3 2 1 1 3 3 3 1 U-box domain Aminotran_3 PF00202.16 EME85698.1 - 1.2e-100 336.6 0.0 1.5e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EME85698.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Alpha-amylase_C PF02806.13 EME85699.1 - 5.3e-24 84.1 0.1 1.2e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EME85699.1 - 9.8e-18 64.6 0.3 4e-14 52.7 0.3 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EME85699.1 - 2e-14 53.4 0.1 4.5e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF2347 PF09804.4 EME85700.1 - 3.8e-82 275.7 0.0 5.4e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EME85700.1 - 4.8e-30 104.9 6.9 6.1e-29 101.3 3.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.5 EME85700.1 - 0.00023 20.8 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EME85700.1 - 0.091 11.2 0.0 12 4.2 0.0 2.8 2 1 1 3 3 3 0 Transport protein Avl9 Iso_dh PF00180.15 EME85701.1 - 6.1e-126 420.0 0.0 6.9e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA PF00004.24 EME85702.1 - 3e-19 69.5 0.0 6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME85702.1 - 0.00064 19.7 2.4 0.0011 19.0 0.4 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME85702.1 - 0.00089 19.4 0.8 0.074 13.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EME85702.1 - 0.0021 17.7 0.0 0.006 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME85702.1 - 0.007 17.1 0.1 0.072 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME85702.1 - 0.0077 15.9 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EME85702.1 - 0.0081 16.0 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 EME85702.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Torsin Zot PF05707.7 EME85702.1 - 0.091 12.2 0.0 17 4.8 0.0 2.9 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) Fibrillarin PF01269.12 EME85704.1 - 1.3e-106 354.6 0.0 1.7e-106 354.2 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EME85704.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EME85704.1 - 0.011 15.2 0.1 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L22 PF00237.14 EME85705.1 - 5e-36 122.8 0.1 7.2e-36 122.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RepB-RCR_reg PF10723.4 EME85705.1 - 9.3 6.0 7.1 2.6 7.8 0.1 2.9 2 1 1 3 3 3 0 Replication regulatory protein RepB His_Phos_1 PF00300.17 EME85706.1 - 7.6e-24 84.5 0.0 9.2e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HMG_box PF00505.14 EME85707.1 - 1.5e-11 44.4 5.4 1.8e-10 40.8 3.8 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EME85707.1 - 1.8e-06 28.2 0.6 2e-06 28.0 0.4 1.1 1 0 0 1 1 1 1 HMG-box domain DUF2207 PF09972.4 EME85708.1 - 0.00027 19.6 1.2 0.077 11.5 0.2 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) DUF4064 PF13273.1 EME85708.1 - 0.0015 18.5 0.1 3.2 7.9 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF4064) MFS_1 PF07690.11 EME85708.1 - 0.0037 16.0 4.1 0.034 12.8 0.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 EME85708.1 - 0.016 15.1 0.9 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4131 PF13567.1 EME85708.1 - 0.022 14.1 2.6 0.14 11.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) COX6A PF02046.10 EME85708.1 - 0.16 11.8 1.1 0.6 10.0 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIa Acetyltransf_1 PF00583.19 EME85709.1 - 2.5e-07 30.6 0.0 3.6e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EME85709.1 - 0.00011 22.6 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME85709.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EME85709.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain His_Phos_1 PF00300.17 EME85710.1 - 1.3e-14 54.6 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SGL PF08450.7 EME85711.1 - 1.7e-29 102.9 0.0 2.2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EME85711.1 - 0.00016 21.4 0.6 0.23 11.4 0.0 3.9 4 0 0 4 4 4 1 NHL repeat Lactonase PF10282.4 EME85711.1 - 0.00036 19.7 0.0 0.00093 18.3 0.0 1.6 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.15 EME85711.1 - 0.0029 17.5 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 Arylesterase PQQ_2 PF13360.1 EME85711.1 - 0.0054 16.2 0.2 0.07 12.5 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain CHU_C PF13585.1 EME85711.1 - 0.039 13.8 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Str_synth PF03088.11 EME85711.1 - 0.081 12.9 0.0 0.41 10.7 0.0 2.2 2 1 1 3 3 3 0 Strictosidine synthase Dabb PF07876.7 EME85712.1 - 3e-13 50.0 0.0 3.3e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.11 EME85712.1 - 0.032 14.2 0.0 0.037 14.0 0.0 1.3 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase FliJ PF02050.11 EME85714.1 - 0.087 12.8 5.9 1.9 8.5 3.4 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein Arena_glycoprot PF00798.13 EME85714.1 - 0.11 10.9 0.0 0.19 10.0 0.0 1.4 1 1 0 1 1 1 0 Arenavirus glycoprotein FlxA PF14282.1 EME85714.1 - 4.5 7.2 8.8 1.4 8.9 3.5 2.1 2 0 0 2 2 2 0 FlxA-like protein TIM PF00121.13 EME85715.1 - 1.2e-87 293.0 0.2 1.3e-87 292.9 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EME85715.1 - 0.021 14.0 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 CutC family AMP-binding PF00501.23 EME85717.1 - 2.1e-40 138.3 0.0 3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME85717.1 - 9e-05 23.3 0.1 0.00025 21.9 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EME85718.1 - 2.9e-33 115.0 14.7 1.2e-31 109.6 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RseC_MucC PF04246.7 EME85718.1 - 0.26 10.8 1.8 0.75 9.3 0.0 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF948 PF06103.6 EME85719.1 - 0.1 12.4 0.9 0.14 12.0 0.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zf-rbx1 PF12678.2 EME85720.1 - 1.2e-10 41.3 0.2 2.2e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EME85720.1 - 2.5e-10 40.0 6.3 1.3e-09 37.7 4.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME85720.1 - 3e-07 30.0 0.8 6.4e-07 29.0 0.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EME85720.1 - 3.9e-07 29.6 0.9 7.9e-07 28.6 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME85720.1 - 2.9e-06 26.8 1.2 8.1e-06 25.4 0.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME85720.1 - 4.1e-05 23.5 1.9 4.1e-05 23.5 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME85720.1 - 0.0023 17.7 0.1 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.9 EME85720.1 - 0.026 14.0 1.1 0.058 12.9 0.8 1.6 1 0 0 1 1 1 0 PQ loop repeat zf-RING_UBOX PF13445.1 EME85720.1 - 0.044 13.5 0.7 0.044 13.5 0.5 2.2 2 1 1 3 3 3 0 RING-type zinc-finger zf-Nse PF11789.3 EME85720.1 - 0.048 13.1 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EME85720.1 - 0.65 10.0 3.6 0.43 10.6 0.8 1.9 2 0 0 2 2 2 0 RING-variant domain DUF2921 PF11145.3 EME85720.1 - 1.3 6.6 6.4 0.075 10.7 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) FANCL_C PF11793.3 EME85720.1 - 3 7.8 4.8 13 5.7 3.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain TcdA_TcdB PF12919.2 EME85721.1 - 0.03 12.8 0.7 0.031 12.7 0.5 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Mt_ATP-synt_B PF05405.9 EME85721.1 - 0.16 11.3 5.7 0.033 13.6 0.9 1.8 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Flagellin_N PF00669.15 EME85721.1 - 0.29 10.9 4.8 0.35 10.6 1.3 2.3 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region DUF964 PF06133.6 EME85721.1 - 0.31 11.0 3.2 1.4 9.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF964) Snapin_Pallidin PF14712.1 EME85721.1 - 1.1 9.6 6.4 4.8 7.5 0.6 3.1 2 1 1 3 3 3 0 Snapin/Pallidin ApoLp-III PF07464.6 EME85721.1 - 1.1 9.2 9.1 2.2 8.2 5.1 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF972 PF06156.8 EME85721.1 - 6.1 7.2 7.2 3.9 7.8 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) YEATS PF03366.11 EME85722.1 - 2.8e-20 71.7 0.0 4.6e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 YEATS family Ran_BP1 PF00638.13 EME85723.1 - 5.5e-50 168.5 1.1 5.5e-50 168.5 0.8 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 EME85723.1 - 0.00016 21.3 0.4 0.0014 18.3 0.1 2.4 2 1 0 2 2 2 1 WH1 domain Daxx PF03344.10 EME85723.1 - 0.27 9.6 17.9 0.34 9.3 12.4 1.2 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 EME85723.1 - 1.5 7.9 27.1 1.8 7.6 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 EME85723.1 - 6.4 4.5 24.4 8.4 4.1 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family Golgin_A5 PF09787.4 EME85725.1 - 0.0074 14.8 0.3 0.011 14.3 0.2 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF4391 PF14335.1 EME85725.1 - 0.076 12.3 3.0 0.13 11.6 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DivIC PF04977.10 EME85725.1 - 0.1 12.0 6.1 0.3 10.5 4.2 1.8 1 0 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 EME85725.1 - 0.19 11.5 5.7 3.7 7.3 2.5 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain IncA PF04156.9 EME85725.1 - 0.28 10.7 6.2 0.45 10.0 4.3 1.2 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EME85725.1 - 4.6 7.6 10.0 10 6.4 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) EF-hand_6 PF13405.1 EME85727.1 - 0.00017 21.1 0.4 0.012 15.4 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EME85727.1 - 0.0014 17.7 0.0 0.19 11.1 0.1 3.6 3 1 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EME85727.1 - 0.0017 18.2 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EME85727.1 - 0.0017 18.4 0.1 0.26 11.4 0.0 2.7 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EME85727.1 - 0.002 17.6 0.1 1.6 8.4 0.0 3.2 2 2 1 3 3 3 3 EF-hand domain pair DOT1 PF08123.8 EME85728.1 - 1.5e-69 233.4 0.0 2.1e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Nucleo_P87 PF07267.6 EME85728.1 - 0.00049 18.9 1.0 0.00071 18.4 0.7 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Methyltransf_26 PF13659.1 EME85728.1 - 0.00079 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME85728.1 - 0.0012 19.4 0.0 0.0049 17.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME85728.1 - 0.0045 16.5 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME85728.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EME85728.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1264 PF06884.6 EME85729.1 - 4.1e-32 110.9 0.5 1e-15 57.6 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1264) F-box PF00646.28 EME85730.1 - 0.00046 19.7 0.1 0.0017 17.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME85730.1 - 0.016 14.9 0.4 0.042 13.5 0.1 1.9 2 0 0 2 2 2 0 F-box-like DUF4449 PF14613.1 EME85732.1 - 9.6e-68 227.2 5.0 9.6e-68 227.2 3.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) ATG16 PF08614.6 EME85733.1 - 4.2e-37 127.8 11.8 4.8e-37 127.6 8.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EME85733.1 - 0.067 13.4 3.3 0.16 12.2 2.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Peptidase_C58 PF03543.9 EME85733.1 - 0.15 11.5 3.5 0.27 10.7 1.9 1.7 1 1 1 2 2 2 0 Yersinia/Haemophilus virulence surface antigen APG6 PF04111.7 EME85733.1 - 0.42 9.5 10.1 0.62 9.0 7.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EME85733.1 - 0.88 8.4 9.9 1.3 7.9 6.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EME85733.1 - 1.9 8.0 17.6 6.7 6.2 12.2 2.0 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 EME85733.1 - 2.1 8.3 11.2 8.4 6.3 7.6 2.0 1 1 1 2 2 2 0 FlxA-like protein V_ATPase_I PF01496.14 EME85733.1 - 6.7 4.4 8.0 8 4.1 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1045 PF06299.7 EME85733.1 - 6.7 6.3 7.8 0.93 9.1 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1045) zf-MYND PF01753.13 EME85734.1 - 1.5e-07 31.1 18.8 1.5e-07 31.1 13.0 1.9 2 0 0 2 2 2 1 MYND finger Arm PF00514.18 EME85735.1 - 1.4e-83 272.1 15.0 6.7e-14 51.1 0.0 7.2 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EME85735.1 - 4.3e-24 84.6 0.7 2.4e-08 34.1 0.0 5.0 1 1 4 5 5 5 5 HEAT repeats IBB PF01749.15 EME85735.1 - 1.1e-23 83.2 1.1 2e-23 82.3 0.8 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EME85735.1 - 3.8e-19 66.9 0.4 1.1e-06 28.2 0.0 6.3 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 EME85735.1 - 1.5e-18 66.6 7.6 7.6e-06 26.2 0.0 6.1 5 1 2 7 7 7 4 HEAT-like repeat Arm_2 PF04826.8 EME85735.1 - 3.4e-10 39.4 0.0 0.016 14.2 0.0 4.1 2 1 2 4 4 4 4 Armadillo-like Adaptin_N PF01602.15 EME85735.1 - 6.1e-06 24.8 0.0 0.0014 17.0 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EME85735.1 - 3.1e-05 23.8 0.0 0.74 9.7 0.0 4.5 5 0 0 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 EME85735.1 - 0.0063 16.4 2.1 7.9 6.4 0.0 4.4 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EME85735.1 - 0.011 14.0 0.1 0.085 11.1 0.0 2.3 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EME85735.1 - 0.014 15.8 3.3 0.16 12.5 0.1 4.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat SURF6 PF04935.7 EME85735.1 - 2 7.6 9.2 3.1 7.0 6.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 EME85736.1 - 5.3e-10 39.3 0.0 2.1e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Sugar_tr PF00083.19 EME85738.1 - 5.3e-107 358.2 25.6 6.2e-107 357.9 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME85738.1 - 7.6e-29 100.5 35.9 1.6e-28 99.4 17.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EME85738.1 - 0.00018 20.3 1.2 0.00037 19.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) DnaJ PF00226.26 EME85739.1 - 3.4e-23 81.1 2.0 5.9e-23 80.3 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EME85739.1 - 1.7e-21 75.9 0.5 3e-19 68.6 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EME85739.1 - 1.6e-14 53.6 15.6 3.2e-14 52.7 10.8 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EME85739.1 - 0.042 13.5 7.5 0.79 9.4 0.5 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EME85739.1 - 0.049 13.9 5.8 0.11 12.9 4.0 1.6 1 0 0 1 1 1 0 Cytochrome c3 Stc1 PF12898.2 EME85739.1 - 0.78 9.8 12.1 3.8 7.6 0.9 2.3 1 1 1 2 2 2 0 Stc1 domain zf-CHY PF05495.7 EME85739.1 - 1.2 9.3 7.3 1.6 8.9 0.7 2.3 2 0 0 2 2 2 0 CHY zinc finger tRNA-synt_1c PF00749.16 EME85740.1 - 9.5e-71 238.0 0.0 1.5e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L4 PF00573.17 EME85741.1 - 5.6e-45 153.0 0.0 7.1e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 EME85742.1 - 9.2e-07 28.7 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MBD_C PF14048.1 EME85742.1 - 0.00062 20.2 0.6 0.0018 18.7 0.4 1.7 1 0 0 1 1 1 1 C-terminal domain of methyl-CpG binding protein 2 and 3 IF3_C PF00707.17 EME85743.1 - 1.5e-08 34.2 0.2 2.7e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EME85743.1 - 5.5e-06 25.8 2.5 2.5e-05 23.7 1.8 1.8 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 EME85743.1 - 1.6e-05 24.7 0.3 6.4e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain tRNA_synt_2f PF02092.12 EME85743.1 - 0.053 12.0 0.1 0.066 11.7 0.1 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit Ank_2 PF12796.2 EME85744.1 - 4.2e-18 65.4 0.8 5.4e-18 65.1 0.5 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EME85744.1 - 8.2e-14 50.6 1.2 1.4e-05 24.6 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EME85744.1 - 8.7e-13 48.4 1.3 2.6e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME85744.1 - 1.9e-12 46.1 0.6 0.00041 20.3 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EME85744.1 - 9.1e-11 41.6 1.0 3.7e-07 30.1 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Fungal_trans PF04082.13 EME85745.1 - 8.9e-16 57.5 2.1 1.7e-15 56.6 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EME85745.1 - 6.6e-08 32.4 13.4 3.3e-05 23.9 4.2 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME85745.1 - 5.6e-06 26.3 13.7 0.0041 17.3 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME85745.1 - 8e-05 22.7 14.7 0.035 14.4 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF3274 PF11678.3 EME85745.1 - 0.024 13.8 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) zf-C2H2_6 PF13912.1 EME85745.1 - 0.32 10.9 4.7 4.7 7.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger RasGEF PF00617.14 EME85747.1 - 3.6e-63 212.6 0.5 6.8e-63 211.8 0.4 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EME85747.1 - 4e-24 84.7 0.0 8.5e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EME85747.1 - 1e-15 56.8 0.1 2.6e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME85747.1 - 1.1e-14 53.7 0.1 2.4e-14 52.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EME85747.1 - 6.7e-13 47.9 0.1 1.4e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EME85747.1 - 4.2e-05 23.3 0.0 8.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 WW domain Glyco_hydro_16 PF00722.16 EME85748.1 - 3e-17 62.5 0.1 3.6e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SusD-like_2 PF12771.2 EME85749.1 - 0.082 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Glyco_hydro_43 PF04616.9 EME85750.1 - 8.3e-32 110.4 0.1 9.8e-32 110.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_22 PF13383.1 EME85750.1 - 0.048 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PhyH PF05721.8 EME85751.1 - 2.7e-27 96.1 0.0 3.7e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RCC1_2 PF13540.1 EME85755.1 - 2.3e-10 39.7 6.5 0.0065 16.0 0.1 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EME85755.1 - 5e-09 36.2 4.6 0.00048 20.2 0.9 5.0 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EME85755.1 - 8.6e-05 22.1 0.1 0.00019 21.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EME85755.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain DUF3006 PF11213.3 EME85755.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) F-box PF00646.28 EME85755.1 - 0.078 12.6 0.1 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box PF00646.28 EME85756.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain HDAC4_Gln PF12203.3 EME85756.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 Peptidase_M16_C PF05193.16 EME85757.1 - 5.9e-42 143.4 0.1 2.3e-40 138.2 0.0 2.7 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EME85757.1 - 2.8e-41 140.7 0.0 1e-40 138.9 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) FHA PF00498.21 EME85758.1 - 3.2e-17 62.4 0.0 6.3e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EME85758.1 - 6.9e-08 32.1 7.9 1.2e-07 31.4 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME85758.1 - 1.5e-05 24.9 2.9 3.3e-05 23.8 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EME85758.1 - 4.9e-05 22.8 7.3 9.2e-05 22.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME85758.1 - 0.00033 20.3 6.1 0.00062 19.4 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME85758.1 - 0.003 17.3 2.6 0.0056 16.4 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EME85758.1 - 0.015 15.3 9.4 0.033 14.1 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EME85758.1 - 0.017 15.0 5.2 0.043 13.8 3.6 1.7 1 0 0 1 1 1 0 RING-like domain Vps39_2 PF10367.4 EME85758.1 - 0.037 14.2 0.6 0.061 13.5 0.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PHD PF00628.24 EME85758.1 - 1.1 9.0 9.9 0.12 12.0 3.6 1.9 2 0 0 2 2 2 0 PHD-finger OrfB_Zn_ribbon PF07282.6 EME85758.1 - 4.7 6.9 6.1 9.7 5.9 0.1 3.1 2 1 1 3 3 3 0 Putative transposase DNA-binding domain HEAT PF02985.17 EME85759.1 - 0.016 15.2 0.1 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.1 EME85759.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats HTH_Tnp_Tc3_1 PF11427.3 EME85760.1 - 0.026 14.1 0.7 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Tc3 transposase MMR_HSR1 PF01926.18 EME85761.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Fungal_trans_2 PF11951.3 EME85764.1 - 9e-20 70.6 0.0 1.3e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME85764.1 - 1.7e-06 27.7 10.7 3e-06 27.0 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MRJP PF03022.11 EME85765.1 - 7.3e-30 104.1 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EME85765.1 - 8.1e-06 25.3 0.3 5.3e-05 22.7 0.2 2.4 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EME85765.1 - 0.17 11.9 2.7 43 4.3 0.0 4.4 5 0 0 5 5 5 0 NHL repeat MFS_1 PF07690.11 EME85767.1 - 1.2e-43 149.2 48.5 1.2e-43 149.2 33.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME85767.1 - 2.4e-16 59.3 15.0 2.4e-16 59.3 10.4 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EME85767.1 - 1.6e-14 53.0 22.4 1.6e-14 53.0 15.5 2.0 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MMR_HSR1 PF01926.18 EME85768.1 - 0.00088 19.2 0.1 0.37 10.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EME85768.1 - 0.0018 18.4 1.3 0.41 10.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.18 EME85768.1 - 0.0059 16.4 5.8 0.021 14.6 1.2 3.6 1 1 1 2 2 2 1 Dynamin family AAA_10 PF12846.2 EME85768.1 - 0.0072 15.7 2.0 0.18 11.2 0.0 3.0 1 1 0 2 2 2 1 AAA-like domain DUF615 PF04751.9 EME85768.1 - 0.14 11.8 12.8 0.13 11.9 2.8 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF615) DUF382 PF04037.8 EME85769.1 - 3.2e-59 198.3 0.2 3.2e-59 198.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EME85769.1 - 8.1e-21 73.1 7.4 1.9e-20 71.9 5.1 1.7 1 0 0 1 1 1 1 PSP Nucleoplasmin PF03066.10 EME85769.1 - 5.4 6.5 22.1 1.9 8.0 7.2 2.4 2 0 0 2 2 2 0 Nucleoplasmin Lge1 PF11488.3 EME85770.1 - 0.00011 22.2 1.2 0.00013 22.0 0.8 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 SURF6 PF04935.7 EME85770.1 - 0.011 15.0 5.5 0.013 14.8 3.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 APG6 PF04111.7 EME85770.1 - 0.016 14.2 2.8 0.017 14.1 1.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 YPEB PF14620.1 EME85770.1 - 0.064 12.2 0.8 0.069 12.1 0.6 1.1 1 0 0 1 1 1 0 YpeB sporulation TBPIP PF07106.8 EME85770.1 - 0.067 12.7 1.6 0.082 12.4 1.1 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG6 PF06419.6 EME85770.1 - 0.096 10.8 1.1 0.12 10.4 0.8 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Birna_RdRp PF04197.7 EME85770.1 - 0.1 10.5 0.4 0.11 10.4 0.3 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) CENP-Q PF13094.1 EME85770.1 - 0.12 12.3 5.3 0.17 11.9 3.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OmpH PF03938.9 EME85770.1 - 0.23 11.4 1.7 0.26 11.1 1.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GrpE PF01025.14 EME85770.1 - 0.32 10.5 3.7 0.4 10.2 2.6 1.2 1 0 0 1 1 1 0 GrpE GTSE1_N PF15259.1 EME85770.1 - 0.35 10.8 4.3 0.68 9.8 2.0 1.8 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 CCDC-167 PF15188.1 EME85770.1 - 0.53 10.2 7.5 0.68 9.9 5.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 HisKA PF00512.20 EME85770.1 - 0.59 10.1 4.4 0.87 9.6 0.2 2.3 1 1 1 2 2 2 0 His Kinase A (phospho-acceptor) domain LsmAD PF06741.8 EME85770.1 - 3 8.0 6.8 1.5 8.9 2.8 1.8 1 1 1 2 2 2 0 LsmAD domain RNA_pol_Rpb2_6 PF00562.23 EME85771.1 - 3.1e-117 391.5 0.1 4.4e-117 391.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EME85771.1 - 2.5e-49 166.9 0.1 4e-49 166.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EME85771.1 - 9.1e-29 99.5 0.7 2.2e-28 98.3 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EME85771.1 - 1.3e-27 96.4 0.1 3e-27 95.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EME85771.1 - 2.6e-20 71.9 0.1 5.6e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EME85771.1 - 9.4e-19 66.9 0.1 1.9e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EME85771.1 - 3.5e-12 46.0 0.3 7.1e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 EME85772.1 - 2.9e-57 187.0 9.0 2.2e-07 29.9 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Mid1 PF12929.2 EME85774.1 - 4.8e-131 437.4 4.0 5.9e-131 437.1 2.8 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EME85774.1 - 0.015 15.6 3.0 0.48 10.7 0.3 2.4 2 0 0 2 2 2 0 Fz domain Abi PF02517.11 EME85776.1 - 7.8e-12 45.1 14.2 7.8e-12 45.1 9.8 3.0 1 1 0 2 2 2 1 CAAX protease self-immunity DUF2636 PF11120.3 EME85776.1 - 0.055 12.9 0.2 1 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Caveolin PF01146.12 EME85776.1 - 0.71 9.4 0.0 0.71 9.4 0.0 2.2 2 1 1 3 3 3 0 Caveolin Spt4 PF06093.8 EME85777.1 - 5.9e-30 102.9 0.7 7.1e-30 102.7 0.5 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-C4 PF00105.13 EME85777.1 - 0.078 13.2 1.3 0.1 12.8 0.9 1.2 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF1272 PF06906.6 EME85777.1 - 0.098 12.5 1.6 0.14 12.0 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Metallophos PF00149.23 EME85778.1 - 4.5e-39 133.9 0.2 7e-39 133.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EME85778.1 - 8.6e-29 99.4 4.4 2.1e-28 98.1 1.1 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EME85778.1 - 2.8e-21 74.9 7.9 8.7e-18 63.7 1.7 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EME85778.1 - 7.8e-16 56.9 4.7 2.1e-06 27.0 0.2 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME85778.1 - 7.5e-11 41.0 2.8 0.0015 18.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME85778.1 - 7.4e-05 22.6 4.8 0.042 14.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EME85778.1 - 0.00055 20.5 1.2 0.42 11.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EME85778.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME85778.1 - 0.052 13.4 1.2 0.42 10.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME85778.1 - 0.12 12.1 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Rep_fac_C PF08542.6 EME85779.1 - 1.9e-21 75.8 0.1 3.7e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EME85779.1 - 1e-11 44.7 0.0 1e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EME85779.1 - 2.3e-11 44.0 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EME85779.1 - 5.2e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EME85779.1 - 2.9e-06 26.2 0.0 0.032 12.9 0.0 2.6 1 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EME85779.1 - 4.2e-06 26.8 0.0 7.8e-05 22.7 0.0 2.3 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 EME85779.1 - 1.8e-05 23.9 0.0 3.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME85779.1 - 2e-05 24.7 0.1 0.0044 17.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 EME85779.1 - 7.4e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EME85779.1 - 0.00016 21.2 0.0 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EME85779.1 - 0.00035 20.0 0.1 0.06 12.7 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EME85779.1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EME85779.1 - 0.0021 17.7 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EME85779.1 - 0.0033 16.6 0.0 0.032 13.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EME85779.1 - 0.0036 16.7 0.1 0.12 11.7 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EME85779.1 - 0.0063 16.2 0.1 0.015 14.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) KTI12 PF08433.5 EME85779.1 - 0.0067 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 EME85779.1 - 0.0068 15.2 0.1 0.017 13.9 0.0 1.5 1 1 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 EME85779.1 - 0.0086 15.7 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 NTPase DEAD PF00270.24 EME85779.1 - 0.0091 15.5 0.1 0.27 10.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_18 PF13238.1 EME85779.1 - 0.022 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EME85779.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 EME85779.1 - 0.028 14.3 0.0 0.069 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EME85779.1 - 0.051 13.1 0.0 0.093 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EME85779.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EME85779.1 - 0.12 12.6 0.0 0.48 10.6 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Glyco_hydro_47 PF01532.15 EME85780.1 - 2.1e-167 557.4 0.1 2.4e-167 557.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mito_fiss_reg PF05308.6 EME85782.1 - 0.084 12.2 2.0 0.081 12.2 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EME85782.1 - 0.1 11.8 0.9 0.11 11.8 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2346 PF09803.4 EME85783.1 - 0.00035 20.3 8.7 0.00095 18.9 5.8 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) 6PF2K PF01591.13 EME85784.1 - 8.9e-68 227.6 0.7 1.7e-67 226.7 0.5 1.5 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EME85784.1 - 1.2e-27 96.9 0.0 8.3e-27 94.2 0.0 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EME85784.1 - 3.5e-08 33.4 0.0 6.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME85784.1 - 2.7e-05 24.9 0.0 9.3e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME85784.1 - 0.001 18.3 0.1 0.0024 17.1 0.1 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EME85784.1 - 0.0075 15.3 0.1 0.048 12.7 0.1 2.1 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EME85784.1 - 0.03 14.6 0.5 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EME85784.1 - 0.049 13.5 0.6 0.21 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Thoc2 PF11732.3 EME85784.1 - 0.15 11.8 0.2 7.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Transcription- and export-related complex subunit DUF202 PF02656.10 EME85786.1 - 0.008 16.3 6.0 0.032 14.4 4.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Cauli_VI PF01693.11 EME85787.1 - 2e-35 120.5 4.0 3.9e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EME85787.1 - 2.7e-28 98.9 0.0 5.5e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EME85787.1 - 0.024 14.4 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase-like Integrase_AP2 PF14657.1 EME85787.1 - 0.033 13.9 0.3 0.092 12.5 0.2 1.7 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain SUI1 PF01253.17 EME85788.1 - 1.6e-17 63.0 0.2 5.4e-17 61.3 0.1 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EME85788.1 - 0.033 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein F-box-like PF12937.2 EME85789.1 - 3.2e-05 23.5 1.1 3.2e-05 23.5 0.8 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME85789.1 - 0.00039 20.0 0.4 0.001 18.6 0.2 1.8 1 0 0 1 1 1 1 F-box domain Myc_target_1 PF15179.1 EME85790.1 - 0.0019 17.8 0.1 0.004 16.7 0.1 1.5 1 0 0 1 1 1 1 Myc target protein 1 SKG6 PF08693.5 EME85790.1 - 0.028 13.7 2.4 0.049 12.9 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EME85790.1 - 0.038 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lamp PF01299.12 EME85790.1 - 0.08 12.0 0.6 0.18 10.8 0.4 1.5 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Rax2 PF12768.2 EME85790.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Rick_17kDa_Anti PF05433.10 EME85791.1 - 0.0002 20.9 15.4 0.00036 20.1 10.7 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EME85791.1 - 0.74 9.4 13.1 2 8.1 9.0 1.7 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EME85791.1 - 2.1 7.9 12.6 5.4 6.6 8.7 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper Glyco_hydro_1 PF00232.13 EME85792.1 - 1.1e-69 234.8 2.4 2.7e-37 128.0 0.6 3.0 2 1 0 2 2 2 2 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EME85792.1 - 0.0031 16.9 0.7 0.0074 15.7 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ABC_tran PF00005.22 EME85793.1 - 3.8e-16 59.6 0.0 4.5e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME85793.1 - 1.9e-10 41.2 0.3 0.00043 20.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EME85793.1 - 1.9e-05 23.8 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 EME85793.1 - 0.00038 20.4 0.1 0.00068 19.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME85793.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EME85793.1 - 0.002 17.4 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 EME85793.1 - 0.0042 16.5 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EME85793.1 - 0.0057 16.6 0.1 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 EME85793.1 - 0.0098 13.2 0.2 0.013 12.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.13 EME85793.1 - 0.0099 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EME85793.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EME85793.1 - 0.026 13.7 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF258 PF03193.11 EME85793.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EME85793.1 - 0.04 13.3 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME85793.1 - 0.042 14.6 0.1 0.078 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EME85793.1 - 0.092 12.9 0.4 0.52 10.5 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EME85793.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EME85793.1 - 0.19 11.1 0.1 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EME85793.1 - 0.2 11.7 0.5 0.59 10.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain IPPT PF01715.12 EME85794.1 - 1.3e-57 194.6 2.5 1.9e-57 194.1 1.8 1.2 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 EME85794.1 - 8.3e-07 29.8 1.1 2.9e-06 28.0 0.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME85794.1 - 5.8e-05 23.0 0.1 0.002 17.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 EME85794.1 - 0.00016 20.9 0.0 0.00047 19.4 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.1 EME85794.1 - 0.0011 19.2 1.9 0.016 15.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EME85794.1 - 0.002 18.4 0.1 0.0068 16.6 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EME85794.1 - 0.016 15.3 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME85794.1 - 0.017 15.0 0.3 0.18 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EME85794.1 - 0.023 14.4 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EME85794.1 - 0.033 14.1 0.4 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EME85794.1 - 0.044 13.1 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EME85794.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 EME85794.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EME85794.1 - 0.11 12.2 2.1 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 WLM PF08325.5 EME85795.1 - 1.6e-48 165.0 0.3 2.5e-48 164.4 0.0 1.4 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 EME85795.1 - 0.00055 19.7 1.6 0.0012 18.7 1.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EME85795.1 - 0.03 13.9 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 EME85795.1 - 0.07 13.1 0.2 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase MA superfamily MARVEL PF01284.18 EME85796.1 - 1.6e-19 70.1 19.7 1.9e-19 69.9 13.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1422 PF07226.6 EME85796.1 - 0.027 14.1 3.2 0.038 13.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) MadM PF03818.8 EME85796.1 - 0.057 13.0 2.2 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit 5TM-5TMR_LYT PF07694.7 EME85796.1 - 0.19 11.0 5.6 0.28 10.5 3.9 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT TMEM237 PF15383.1 EME85796.1 - 0.55 9.3 4.1 0.7 8.9 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 DUF3624 PF12292.3 EME85796.1 - 1.8 9.0 11.7 0.069 13.5 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) AMP-binding PF00501.23 EME85797.1 - 2.4e-84 283.1 0.0 2.9e-84 282.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HARP PF07443.8 EME85797.1 - 0.028 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) DUF162 PF02589.10 EME85797.1 - 0.041 13.4 0.3 0.1 12.1 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 Cys_Met_Meta_PP PF01053.15 EME85798.1 - 2.9e-147 490.0 0.0 3.3e-147 489.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EME85798.1 - 5.5e-12 45.3 0.2 9.7e-12 44.5 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EME85798.1 - 6.7e-10 38.4 0.0 1.9e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME85798.1 - 3.2e-07 29.4 0.1 4.9e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME85798.1 - 4.3e-06 26.0 0.0 8.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EME85798.1 - 3.9e-05 22.1 0.1 5e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EME85798.1 - 0.011 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CPSase_L_D2 PF02786.12 EME85798.1 - 0.053 12.8 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TRAPPC10 PF12584.3 EME85799.1 - 6.4e-12 45.1 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF708 PF05341.6 EME85799.1 - 0.051 13.3 0.0 7.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF708) QCR10 PF09796.4 EME85800.1 - 1.6e-20 72.5 0.1 2.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3237 PF11578.3 EME85801.1 - 3e-33 114.2 0.0 3.5e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Chs3p PF12271.3 EME85802.1 - 8.8e-97 323.6 2.1 1e-96 323.4 1.5 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF4059 PF13268.1 EME85802.1 - 0.0093 16.1 0.2 2.5 8.3 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4059) Lysis_S PF04971.7 EME85802.1 - 0.067 12.8 0.0 0.3 10.7 0.0 2.1 1 0 0 1 1 1 0 Lysis protein S FixQ PF05545.6 EME85802.1 - 0.8 9.3 8.9 4.8 6.9 0.1 3.7 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DPM3 PF08285.6 EME85802.1 - 1.5 8.7 8.1 4.6 7.1 0.1 3.4 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Hydrolase PF00702.21 EME85803.1 - 1.1e-22 81.4 0.0 9.5e-22 78.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EME85803.1 - 2.5e-21 75.7 0.0 7.2e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EME85803.1 - 1.3e-18 67.8 0.0 2.6e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME85803.1 - 0.00012 21.9 0.1 0.00049 20.0 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EME85803.1 - 0.0072 15.7 0.0 0.022 14.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EME85803.1 - 0.0095 15.5 0.3 0.049 13.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Bac_rhamnosid PF05592.6 EME85804.1 - 1.6e-08 33.2 1.3 4.4e-05 21.8 0.0 3.3 4 0 0 4 4 4 2 Bacterial alpha-L-rhamnosidase AIF-MLS PF14962.1 EME85804.1 - 0.27 10.8 0.2 0.48 10.0 0.2 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DAO PF01266.19 EME85806.1 - 1.6e-38 132.5 0.0 2.2e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME85806.1 - 0.00041 20.1 0.1 0.0019 17.9 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME85806.1 - 0.00046 20.1 0.0 0.0015 18.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME85806.1 - 0.002 18.0 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME85806.1 - 0.0023 18.0 0.0 0.0054 16.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EME85806.1 - 0.0059 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EME85806.1 - 0.0079 16.2 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EME85806.1 - 0.017 14.0 0.0 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain PPR_2 PF13041.1 EME85807.1 - 9.2e-15 54.3 0.8 0.00025 20.9 0.0 6.7 6 1 0 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EME85807.1 - 6.8e-11 41.5 7.3 0.015 15.5 0.0 9.0 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EME85807.1 - 9.1e-06 25.0 2.9 1.4 8.5 0.0 6.1 7 0 0 7 7 7 2 PPR repeat PPR PF01535.15 EME85807.1 - 1.7e-05 24.4 3.5 0.093 12.7 0.0 5.6 4 1 0 4 4 4 1 PPR repeat TPR_19 PF14559.1 EME85807.1 - 0.0025 18.1 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EME85807.1 - 0.016 15.3 0.1 0.15 12.1 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4288 PF14119.1 EME85807.1 - 0.057 13.5 0.1 0.58 10.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Ribosomal_S13 PF00416.17 EME85808.1 - 4.5e-40 136.4 1.4 5.4e-40 136.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EME85808.1 - 0.0063 15.1 0.0 0.0063 15.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EME85808.1 - 0.12 12.4 0.3 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 MCM PF00493.18 EME85810.1 - 8.9e-128 425.7 0.3 1.3e-127 425.1 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EME85810.1 - 9.3e-15 55.1 0.0 2.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EME85810.1 - 7.8e-07 28.4 0.0 9.6e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EME85810.1 - 0.004 16.7 0.0 0.0081 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME85810.1 - 0.077 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Fer4_10 PF13237.1 EME85811.1 - 0.024 14.4 0.3 0.054 13.3 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain p450 PF00067.17 EME85813.1 - 1.2e-61 208.6 0.0 1.5e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GYF PF02213.11 EME85815.1 - 1.1e-16 60.1 0.3 3.3e-16 58.6 0.2 1.9 1 0 0 1 1 1 1 GYF domain CRT10 PF08728.5 EME85815.1 - 2.1 6.2 2.1 3.1 5.6 1.5 1.1 1 0 0 1 1 1 0 CRT10 Glyco_hydro_92 PF07971.7 EME85816.1 - 9.8e-164 545.6 0.3 1.2e-163 545.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 RHD3 PF05879.7 EME85819.1 - 0 1023.4 0.0 0 1023.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EME85819.1 - 3.3e-09 36.1 0.1 5.6e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EME85819.1 - 8.5e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EME85819.1 - 8.5e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME85819.1 - 0.0017 18.8 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EME85819.1 - 0.014 14.4 0.1 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_28 PF13521.1 EME85819.1 - 0.017 15.0 0.3 0.06 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain CLPTM1 PF05602.7 EME85820.1 - 3e-154 513.9 0.0 3.6e-154 513.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.6 EME85820.1 - 0.063 13.0 0.5 1.9 8.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) 2TM PF13239.1 EME85820.1 - 1 9.4 5.6 0.28 11.2 0.1 2.8 3 0 0 3 3 3 0 2TM domain Choline_transpo PF04515.7 EME85821.1 - 1.9e-12 46.5 18.2 5.2e-12 45.1 11.9 3.4 3 1 1 4 4 4 2 Plasma-membrane choline transporter DUF4064 PF13273.1 EME85821.1 - 0.038 14.0 0.8 0.038 14.0 0.6 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) Glyco_hydro_cc PF11790.3 EME85822.1 - 1.1e-43 149.3 0.5 1.3e-43 149.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Haem_bd PF14376.1 EME85822.1 - 0.052 13.2 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Haem-binding domain Gin PF10764.4 EME85822.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin FAD_binding_4 PF01565.18 EME85824.1 - 3.4e-24 84.8 2.6 5.6e-24 84.1 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME85824.1 - 0.0072 16.2 0.2 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF2066 PF09839.4 EME85824.1 - 0.08 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) CAF-1_p150 PF11600.3 EME85826.1 - 0.0016 17.8 28.2 0.0016 17.8 19.6 3.2 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.9 EME85826.1 - 0.026 14.4 13.7 0.057 13.3 9.5 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DBINO PF13892.1 EME85826.1 - 1.8 8.5 22.0 3.7 7.5 15.3 1.4 1 0 0 1 1 1 0 DNA-binding domain NARP1 PF12569.3 EME85826.1 - 2.4 6.7 24.1 3.7 6.1 16.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LSM PF01423.17 EME85827.1 - 5e-19 67.6 0.2 6.5e-19 67.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF3628 PF12300.3 EME85827.1 - 1.6 8.6 7.4 2.5 8.0 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) FoP_duplication PF13865.1 EME85827.1 - 3.6 8.0 11.5 6.6 7.2 7.9 1.5 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.13 EME85828.1 - 0.49 10.3 12.4 1.7 8.6 8.6 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 EME85829.1 - 4.1e-05 23.6 1.3 4.1e-05 23.6 0.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EME85829.1 - 0.00075 19.6 5.7 0.056 13.8 1.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME85829.1 - 0.0049 17.1 13.0 0.0053 17.0 0.8 3.7 5 0 0 5 5 5 2 C2H2-type zinc finger Polyketide_cyc2 PF10604.4 EME85830.1 - 2e-07 31.2 0.1 2.2e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TruD PF01142.13 EME85831.1 - 4.3e-54 183.6 0.5 5.4e-50 170.1 0.1 4.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) eIF2A PF08662.6 EME85834.1 - 0.00019 21.2 0.0 0.0043 16.7 0.0 2.5 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EME85834.1 - 0.00019 20.6 0.3 8 5.8 0.0 3.7 3 0 0 3 3 3 3 Proteasome subunit A N-terminal signature WD40 PF00400.27 EME85834.1 - 0.0002 21.1 8.1 0.66 9.9 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat IKI3 PF04762.7 EME85834.1 - 0.00021 19.3 0.1 0.0021 16.0 0.0 2.1 2 0 0 2 2 2 1 IKI3 family PD40 PF07676.7 EME85834.1 - 0.00037 20.0 0.8 0.08 12.6 0.2 2.9 2 1 0 2 2 2 2 WD40-like Beta Propeller Repeat PEX11 PF05648.9 EME85835.1 - 2e-14 53.4 0.0 7.8e-14 51.4 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GntP_permease PF02447.11 EME85837.1 - 0.021 13.3 0.1 0.03 12.8 0.1 1.2 1 0 0 1 1 1 0 GntP family permease bZIP_1 PF00170.16 EME85838.1 - 1.8e-09 37.4 8.5 1.8e-09 37.4 5.9 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EME85838.1 - 1.4e-05 24.8 8.5 1.4e-05 24.8 5.9 3.0 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME85838.1 - 0.0053 17.0 7.5 0.0053 17.0 5.2 2.9 3 0 0 3 3 3 1 bZIP Maf transcription factor Bacteriocin_IIc PF10439.4 EME85840.1 - 7.6 6.7 9.3 9.5 6.4 0.9 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RRM_6 PF14259.1 EME85841.1 - 1.1e-12 47.7 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME85841.1 - 5.6e-11 41.9 0.0 9.5e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME85841.1 - 0.00047 19.9 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ERG4_ERG24 PF01222.12 EME85843.1 - 8e-77 258.5 10.6 3.2e-76 256.5 7.4 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CAP_GLY PF01302.20 EME85843.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain SprT-like PF10263.4 EME85845.1 - 6.3e-07 29.1 0.0 2.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 SprT-like family Mpv17_PMP22 PF04117.7 EME85846.1 - 6.5e-13 48.1 0.8 7.1e-11 41.5 0.3 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family DUF3557 PF12078.3 EME85846.1 - 0.053 13.2 0.1 0.91 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) NADH_oxidored PF08040.6 EME85846.1 - 0.081 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit Multi_ubiq PF14452.1 EME85848.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Multiubiquitin SQS_PSY PF00494.14 EME85849.1 - 6.2e-46 156.8 0.1 8.1e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 EME85850.1 - 7.3e-71 238.3 0.2 1.4e-70 237.4 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.6 EME85850.1 - 1.7e-15 56.8 0.0 3.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EME85850.1 - 1.8e-13 50.1 0.0 4.7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EME85850.1 - 3.5e-06 26.9 11.7 7.3e-06 25.9 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 EME85850.1 - 7.6e-05 22.1 0.1 0.00018 20.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_3 PF13920.1 EME85850.1 - 0.00091 18.8 9.6 0.0018 17.9 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME85850.1 - 0.0012 18.4 12.0 0.0025 17.4 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME85850.1 - 0.0014 18.3 11.0 0.0029 17.3 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EME85850.1 - 0.033 13.9 10.5 0.1 12.3 7.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.1 EME85850.1 - 0.21 11.4 3.1 0.54 10.0 2.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Eaf7 PF07904.8 EME85852.1 - 4.7e-18 64.9 0.0 1e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 DUF2201_N PF13203.1 EME85852.1 - 3.5 6.7 8.7 5.3 6.1 6.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain PKD_channel PF08016.7 EME85853.1 - 1.8e-05 23.3 16.1 0.00047 18.7 11.1 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EME85853.1 - 0.0029 16.8 26.1 0.054 12.7 18.1 2.2 1 1 0 1 1 1 1 Ion transport protein GFO_IDH_MocA PF01408.17 EME85854.1 - 3.9e-21 75.7 0.1 7.8e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME85854.1 - 0.0053 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MIP PF00230.15 EME85856.1 - 2.6e-38 131.7 15.5 3.3e-38 131.4 10.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein E1-E2_ATPase PF00122.15 EME85859.1 - 1.4e-56 191.1 3.6 1.4e-56 191.1 2.5 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME85859.1 - 2.8e-44 150.8 8.1 2.8e-44 150.8 5.6 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME85859.1 - 8.2e-30 104.8 0.0 1.9e-29 103.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME85859.1 - 6.8e-17 61.2 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EME85859.1 - 5.5e-13 49.5 0.0 1.8e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME85859.1 - 3.2e-10 39.3 0.2 2e-09 36.7 0.1 2.3 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EME85859.1 - 2.2e-05 24.1 0.2 0.00026 20.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EME85859.1 - 0.035 14.0 0.0 0.035 14.0 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3325) DUF3325 PF11804.3 EME85860.1 - 7.6 6.5 10.3 15 5.5 6.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) SLT PF01464.15 EME85861.1 - 0.014 14.8 0.0 0.045 13.2 0.0 1.8 1 1 0 1 1 1 0 Transglycosylase SLT domain Lysozyme_like PF13702.1 EME85861.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Lysozyme-like Abhydrolase_4 PF08386.5 EME85862.1 - 8.6e-21 73.7 0.0 1.9e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EME85862.1 - 1.1e-15 57.8 0.1 2.7e-13 50.0 0.0 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME85862.1 - 9.5e-10 38.7 0.0 5.9e-09 36.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family TFIIIC_delta PF12657.2 EME85862.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Cellulase PF00150.13 EME85864.1 - 2.3e-19 69.6 1.3 3.4e-19 69.1 0.9 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EME85864.1 - 3.6e-07 30.5 0.0 8.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EME85864.1 - 1.3e-06 27.5 0.2 4.9e-05 22.3 0.1 3.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EME85864.1 - 0.0045 16.1 0.0 0.0099 15.0 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 EME85864.1 - 0.0066 15.5 0.0 0.13 11.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.19 EME85865.1 - 1.3e-72 244.8 20.3 1.5e-72 244.6 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME85865.1 - 6.6e-24 84.2 25.9 6.6e-24 84.2 17.9 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily ALMS_motif PF15309.1 EME85866.1 - 0.004 17.0 6.1 0.39 10.5 1.4 3.4 1 1 1 3 3 3 2 ALMS motif Phage_gp53 PF11246.3 EME85866.1 - 2.2 7.6 3.8 14 5.0 0.3 2.5 3 0 0 3 3 3 0 Base plate wedge protein 53 Lipoprotein_Ltp PF07553.6 EME85866.1 - 3.1 7.7 7.5 2.6 7.9 0.4 3.3 3 0 0 3 3 3 0 Host cell surface-exposed lipoprotein Phage_Coat_Gp8 PF05371.7 EME85867.1 - 0.014 14.9 1.6 0.065 12.7 0.4 2.7 2 0 0 2 2 2 0 Phage major coat protein, Gp8 NUDIX PF00293.23 EME85868.1 - 2.6e-15 56.2 0.1 6.9e-15 54.8 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain Glyco_hydro_61 PF03443.9 EME85870.1 - 5.3e-81 271.5 0.2 8.5e-81 270.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 VTC PF09359.5 EME85871.1 - 3.8e-95 318.1 0.6 7.1e-95 317.2 0.4 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EME85871.1 - 1.1e-18 67.9 7.2 1.1e-18 67.9 5.0 3.4 2 2 1 3 3 3 1 SPX domain DUF202 PF02656.10 EME85871.1 - 6.4e-12 45.5 1.4 1.2e-11 44.6 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TRAPPC9-Trs120 PF08626.6 EME85872.1 - 2.1e-75 253.9 0.0 6.7e-75 252.2 0.0 1.8 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Rap_GAP PF02145.10 EME85873.1 - 4e-47 160.0 0.0 6.6e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EME85873.1 - 4e-24 85.3 0.7 2.7e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.3 EME85873.1 - 2.2e-06 26.4 0.0 4.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Velvet PF11754.3 EME85875.1 - 2.2e-63 213.5 0.0 4.4e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 Velvet factor HemY_N PF07219.8 EME85878.1 - 0.028 13.9 0.1 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DUF1180 PF06679.7 EME85878.1 - 0.029 14.2 0.2 0.029 14.2 0.1 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) VIT1 PF01988.14 EME85878.1 - 0.079 12.4 0.2 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 VIT family MSC PF09402.5 EME85878.1 - 0.093 11.4 0.1 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain EphA2_TM PF14575.1 EME85878.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EME85878.1 - 0.17 11.6 1.2 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 TMEM154 protein family DUF1049 PF06305.6 EME85878.1 - 0.22 11.0 1.0 0.37 10.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) PepSY_TM_2 PF13703.1 EME85878.1 - 0.23 11.6 2.2 0.59 10.3 1.5 1.6 1 1 0 1 1 1 0 PepSY-associated TM helix GAPT PF11770.3 EME85878.1 - 7.9 6.1 6.0 8.3 6.0 0.1 2.1 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) Sigma70_r4_2 PF08281.7 EME85881.1 - 0.1 12.0 0.3 8.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 Acyl-CoA_dh_1 PF00441.19 EME85882.1 - 8.7e-38 129.7 0.4 1.4e-37 129.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EME85882.1 - 2.7e-16 60.0 0.0 4.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME85882.1 - 3.8e-15 55.1 0.2 8e-15 54.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME85882.1 - 1.2e-09 38.7 1.9 1e-08 35.7 0.4 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 EME85882.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CAP_GLY PF01302.20 EME85884.1 - 2e-26 91.4 0.3 3e-26 90.8 0.2 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EME85884.1 - 1.2e-17 63.9 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EME85884.1 - 0.00027 20.2 0.0 0.00051 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF4048 PF13257.1 EME85885.1 - 0.28 10.7 3.1 5.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4048) Myb_DNA-binding PF00249.26 EME85886.1 - 2.1e-12 46.8 3.8 1.1e-08 34.9 0.0 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME85886.1 - 1.1e-09 38.2 5.6 2.6e-06 27.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Abp2 PF09441.5 EME85887.1 - 7.8e-81 270.1 0.0 1.4e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.11 EME85887.1 - 0.0025 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family UPRTase PF14681.1 EME85888.1 - 1.2e-75 253.2 0.0 1.4e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EME85888.1 - 6.4e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EME85888.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CRCB PF02537.10 EME85889.1 - 1.7e-29 102.0 22.2 5.6e-19 68.1 6.6 3.3 3 1 0 3 3 3 2 CrcB-like protein Macoilin PF09726.4 EME85889.1 - 7.4 4.7 9.4 9.9 4.3 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Abhydrolase_6 PF12697.2 EME85890.1 - 1.2e-18 67.8 0.0 1.6e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME85890.1 - 2.8e-06 27.1 0.0 9.3e-06 25.4 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family PalH PF08733.5 EME85891.1 - 2.4e-102 342.3 0.0 1.1e-100 336.9 0.0 2.0 1 1 0 1 1 1 1 PalH/RIM21 UreD PF01774.12 EME85892.1 - 1.2e-52 178.4 0.0 1.5e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EME85893.1 - 5e-30 103.6 0.7 2.7e-29 101.2 0.4 2.4 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EME85893.1 - 1.3e-07 31.7 0.8 0.019 15.2 0.0 3.3 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EME85893.1 - 0.0066 16.4 0.7 12 6.2 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Xpo1 PF08389.7 EME85893.1 - 0.083 12.7 0.8 3 7.7 0.1 3.2 2 1 0 2 2 2 0 Exportin 1-like protein DUF3895 PF13034.1 EME85894.1 - 0.021 14.2 0.1 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Cullin_binding PF03556.10 EME85895.1 - 2.2e-31 108.3 7.1 3.8e-31 107.6 4.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EME85895.1 - 2.8e-13 49.1 0.1 4.8e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain AAA_18 PF13238.1 EME85895.1 - 0.085 13.1 0.3 2.8 8.2 0.1 2.7 3 1 0 3 3 3 0 AAA domain PX PF00787.19 EME85896.1 - 3.4e-17 62.2 0.2 7.5e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 EME85896.1 - 0.053 12.0 6.0 0.41 9.1 4.1 2.2 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3552 PF12072.3 EME85896.1 - 0.098 11.8 4.8 0.16 11.1 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Fib_alpha PF08702.5 EME85896.1 - 0.13 12.3 0.7 0.27 11.3 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Fungal_trans PF04082.13 EME85897.1 - 3.3e-24 85.1 0.3 5.7e-24 84.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME85897.1 - 5.1e-08 32.7 10.6 8.2e-08 32.0 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EME85898.1 - 3.6e-75 253.1 41.3 4.8e-57 193.3 16.7 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EME85898.1 - 9.1e-26 90.3 38.9 1.1e-21 76.9 15.9 2.1 1 1 1 2 2 2 2 Amino acid permease HAD_2 PF13419.1 EME85899.1 - 3.5e-20 72.9 0.0 4.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME85899.1 - 0.00068 20.1 0.0 0.0034 17.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EME85899.1 - 0.031 14.1 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ETF PF01012.16 EME85899.1 - 0.039 13.6 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein domain LpxC PF03331.8 EME85899.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase DAO PF01266.19 EME85900.1 - 8.2e-60 202.5 0.0 9.7e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME85900.1 - 5.7e-06 26.5 0.2 0.00023 21.2 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME85900.1 - 9.4e-05 22.2 2.0 0.0015 18.3 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME85900.1 - 0.0001 22.2 0.1 0.00027 20.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME85900.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EME85900.1 - 0.0017 18.3 0.2 0.0092 15.8 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME85900.1 - 0.0019 17.2 0.1 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 EME85900.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EME85900.1 - 0.031 12.7 0.6 0.84 8.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 EME85900.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EME85900.1 - 0.12 11.2 0.6 0.19 10.5 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Malic_M PF03949.10 EME85900.1 - 0.15 11.6 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DSBA PF01323.15 EME85901.1 - 5e-29 101.2 0.0 5.7e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EME85901.1 - 1.2e-07 31.9 0.3 2.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EME85901.1 - 0.00038 20.6 0.0 0.033 14.3 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain NMT1 PF09084.6 EME85902.1 - 2.9e-27 95.6 0.1 3.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like 4HBT PF03061.17 EME85903.1 - 1.3e-06 28.3 0.1 3.6e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Thioesterase superfamily Bestrophin PF01062.16 EME85904.1 - 1.1e-45 155.8 0.3 4.8e-45 153.7 0.2 1.8 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1772 PF08592.6 EME85907.1 - 1.5e-08 34.4 1.6 3e-06 27.0 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) EF1G PF00647.14 EME85908.1 - 4.5e-46 154.9 0.3 7.4e-46 154.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EME85908.1 - 8.6e-12 44.8 3.5 9.2e-12 44.7 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME85908.1 - 4.1e-10 39.6 0.1 1.5e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EME85908.1 - 3.1e-08 33.7 0.0 7.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME85908.1 - 1.3e-07 31.4 0.9 1.5e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME85908.1 - 1.8e-05 25.1 0.2 3.6e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EME85908.1 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.14 EME85909.1 - 2.4e-36 124.6 0.2 3.6e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Isochorismatase PF00857.15 EME85910.1 - 1.2e-12 48.1 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family zf-C2H2 PF00096.21 EME85911.1 - 1.7 9.1 11.0 0.52 10.7 0.9 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type EST1_DNA_bind PF10373.4 EME85912.1 - 5.7e-51 173.3 0.0 9e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EME85912.1 - 7.6e-12 45.3 0.0 2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EME85912.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Peptidase_M24 PF00557.19 EME85914.1 - 1e-52 178.7 0.0 1.9e-52 177.8 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EME85914.1 - 5.8e-25 87.2 0.0 1.9e-24 85.5 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Thaumatin PF00314.12 EME85915.1 - 2.9e-71 239.3 8.1 4.1e-71 238.8 5.6 1.2 1 0 0 1 1 1 1 Thaumatin family DUF371 PF04027.8 EME85916.1 - 0.19 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) NAD_binding_10 PF13460.1 EME85917.1 - 5.7e-24 85.1 0.1 7.6e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME85917.1 - 7.5e-11 41.9 0.0 1.9e-10 40.6 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME85917.1 - 2.1e-05 23.9 0.3 0.0011 18.2 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EME85917.1 - 8.8e-05 21.5 0.0 0.00072 18.5 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EME85917.1 - 0.00048 20.0 0.3 0.0028 17.5 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EME85917.1 - 0.003 16.2 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EME85917.1 - 0.034 13.0 0.0 0.067 12.0 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain PAC2 PF09754.4 EME85917.1 - 0.061 13.1 0.0 8.2 6.2 0.0 2.2 1 1 1 2 2 2 0 PAC2 family KR PF08659.5 EME85917.1 - 0.085 12.5 0.2 0.28 10.8 0.1 2.0 2 1 0 2 2 2 0 KR domain NAD_binding_2 PF03446.10 EME85918.1 - 4.6e-29 101.3 0.1 5.9e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EME85918.1 - 5e-14 52.4 0.1 9e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME85918.1 - 0.00014 21.2 0.0 0.0046 16.3 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EME85918.1 - 0.00099 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EME85918.1 - 0.0014 18.9 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EME85918.1 - 0.0032 17.1 0.2 0.0098 15.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EME85918.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EME85918.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain EF-hand_1 PF00036.27 EME85919.1 - 4.4e-26 88.1 12.5 7.4e-07 28.0 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EME85919.1 - 7.4e-23 80.4 3.5 2.1e-12 47.0 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EME85919.1 - 6.7e-20 69.1 5.1 5e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EME85919.1 - 3.4e-18 64.0 11.7 6.2e-06 25.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EME85919.1 - 3.3e-15 55.4 13.4 1.3e-05 24.6 0.6 4.8 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EME85919.1 - 1.5e-06 28.2 0.0 0.0009 19.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EME85919.1 - 6e-06 25.9 8.2 0.002 17.8 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EME85919.1 - 0.044 13.7 0.1 1.4 8.8 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain DUF1770 PF08589.5 EME85920.1 - 1.1e-18 67.6 0.8 1.4e-18 67.2 0.6 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Sedlin_N PF04628.8 EME85920.1 - 0.14 12.0 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Cupin_2 PF07883.6 EME85922.1 - 8.2e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.3 EME85922.1 - 0.032 14.1 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_1 PF00190.17 EME85922.1 - 0.06 12.7 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Cupin ADH_zinc_N PF00107.21 EME85923.1 - 1.3e-09 37.6 0.0 9.7e-09 34.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME85923.1 - 1.9e-07 32.0 0.0 4.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME85923.1 - 9.5e-05 22.1 0.0 0.0014 18.3 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EME85923.1 - 0.0055 16.7 0.6 0.011 15.7 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME85923.1 - 0.014 14.7 0.1 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.20 EME85923.1 - 0.024 14.5 1.1 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.16 EME85923.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Laminin_II PF06009.7 EME85924.1 - 0.0067 16.1 8.6 0.0067 16.1 6.0 2.3 1 1 1 2 2 2 1 Laminin Domain II Filament PF00038.16 EME85926.1 - 0.32 10.4 40.6 0.055 12.9 9.1 2.8 1 1 2 3 3 3 0 Intermediate filament protein TcdB_N PF12918.2 EME85926.1 - 0.7 10.0 10.8 0.88 9.6 0.4 3.4 2 1 1 3 3 3 0 TcdB toxin N-terminal helical domain Fis1_TPR_C PF14853.1 EME85927.1 - 1.5e-25 88.8 1.1 2.2e-25 88.2 0.8 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EME85927.1 - 1.7e-16 59.2 0.0 3.3e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EME85927.1 - 0.00016 21.3 1.9 0.00035 20.2 1.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME85927.1 - 0.0054 16.2 3.1 0.012 15.2 2.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME85927.1 - 0.0092 16.6 1.1 0.012 16.2 0.1 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME85927.1 - 0.013 15.8 0.2 0.032 14.5 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME85927.1 - 0.038 14.4 0.2 0.2 12.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME85927.1 - 0.043 13.4 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 TPR repeat DUF3361 PF11841.3 EME85927.1 - 0.1 12.3 0.0 1.3 8.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) DUF357 PF04010.8 EME85927.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Spc24 PF08286.6 EME85928.1 - 3.8e-31 107.2 0.9 4.2e-29 100.6 0.0 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 APG6 PF04111.7 EME85928.1 - 0.019 14.0 3.7 0.024 13.7 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4164 PF13747.1 EME85928.1 - 0.028 14.5 8.2 1.8 8.7 5.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF2580 PF10824.3 EME85928.1 - 0.12 12.7 1.0 0.24 11.7 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2580) DUF607 PF04678.8 EME85928.1 - 0.12 12.3 2.2 5.3 6.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Cortex-I_coil PF09304.5 EME85928.1 - 0.17 11.9 6.5 0.11 12.5 0.6 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EME85928.1 - 0.27 9.0 1.9 0.3 8.8 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Polyketide_cyc2 PF10604.4 EME85932.1 - 5.3e-05 23.4 0.9 0.00033 20.8 0.6 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EME85932.1 - 0.00043 20.2 0.1 0.00066 19.6 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FYVE PF01363.16 EME85934.1 - 2.7e-15 56.0 11.0 3.4e-15 55.6 6.4 1.9 1 1 1 2 2 2 2 FYVE zinc finger GMC_oxred_N PF00732.14 EME85935.1 - 2.6e-40 138.4 1.5 4.6e-40 137.6 1.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME85935.1 - 9e-26 90.8 0.0 2.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.12 EME85935.1 - 1.2e-06 27.7 0.1 3.1e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EME85935.1 - 1.9e-06 27.7 1.8 6.8e-05 22.8 0.5 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME85935.1 - 2.4e-06 27.6 0.6 5.3e-06 26.4 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME85935.1 - 9.3e-06 24.9 0.1 1.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME85935.1 - 2.8e-05 23.1 12.5 8.5e-05 21.6 8.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME85935.1 - 7.2e-05 21.8 8.9 0.00022 20.2 6.1 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EME85935.1 - 0.019 14.0 2.2 0.034 13.2 1.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EME85935.1 - 0.02 14.5 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EME85935.1 - 0.033 13.0 0.4 0.055 12.3 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EME85935.1 - 0.047 14.0 0.1 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME85935.1 - 0.049 12.0 0.2 0.074 11.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EME85935.1 - 0.084 11.7 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 EME85935.1 - 0.17 11.7 0.5 0.38 10.5 0.3 1.5 1 0 0 1 1 1 0 ThiF family PPR_2 PF13041.1 EME85936.1 - 8.3e-18 64.1 0.0 7.9e-06 25.7 0.0 5.2 4 1 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 EME85936.1 - 7.8e-09 35.1 5.1 0.073 13.3 0.1 7.0 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EME85936.1 - 1.3e-07 31.1 1.4 0.00046 19.9 0.0 4.4 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EME85936.1 - 3.1e-05 23.3 0.0 0.0016 17.8 0.0 3.2 3 0 0 3 3 3 1 PPR repeat MAM33 PF02330.11 EME85936.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein His_Phos_2 PF00328.17 EME85937.1 - 1.7e-25 90.1 0.0 3.4e-25 89.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Na_H_Exchanger PF00999.16 EME85938.1 - 4.3e-71 239.4 18.7 5.1e-71 239.1 13.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EME85938.1 - 1.3e-45 156.4 46.1 2.3e-37 129.3 21.8 2.2 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4190 PF13828.1 EME85938.1 - 0.11 12.0 2.2 2.2 7.8 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) DUF2392 PF10288.4 EME85939.1 - 3.3e-27 94.9 0.0 9.2e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) Cu-oxidase_3 PF07732.10 EME85942.1 - 1.8e-40 137.3 3.2 9.7e-40 134.9 1.6 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME85942.1 - 3.9e-38 130.0 0.4 3.9e-38 130.0 0.3 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EME85942.1 - 3.3e-32 111.6 2.6 4e-32 111.3 0.3 2.3 2 1 1 3 3 3 1 Multicopper oxidase zf-Mss51 PF13824.1 EME85943.1 - 2.3e-24 84.9 5.8 4.4e-24 84.0 4.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 CPSF_A PF03178.10 EME85944.1 - 2.1e-90 303.0 0.0 6.5e-90 301.4 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EME85944.1 - 2.6e-42 144.6 0.0 3.5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term F-box PF00646.28 EME85945.1 - 0.051 13.2 0.1 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EME85945.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like ABC_tran PF00005.22 EME85946.1 - 1.2e-46 158.4 0.1 1.8e-23 83.3 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME85946.1 - 2.4e-16 60.5 0.8 0.0023 17.9 0.1 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EME85946.1 - 3.1e-15 56.0 0.1 9.7e-06 24.9 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME85946.1 - 6.4e-09 35.2 0.0 0.0028 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 EME85946.1 - 7e-08 32.6 0.2 0.079 13.2 0.0 3.7 1 1 2 3 3 3 2 HEAT repeats AAA_23 PF13476.1 EME85946.1 - 1.1e-07 32.3 9.7 0.015 15.6 0.1 3.4 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME85946.1 - 1.3e-07 32.4 0.0 0.0074 17.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EME85946.1 - 2.5e-07 30.8 0.0 0.028 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EME85946.1 - 6e-07 29.6 0.0 0.0069 16.5 0.0 3.7 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 EME85946.1 - 1.4e-06 27.5 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EME85946.1 - 3.5e-06 26.5 0.1 0.12 11.8 0.0 3.3 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EME85946.1 - 6.1e-06 26.4 0.1 0.11 12.6 0.0 4.4 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EME85946.1 - 7.2e-06 25.6 0.1 0.27 10.6 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 EME85946.1 - 1e-05 25.4 0.0 0.02 14.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EME85946.1 - 1.1e-05 25.5 1.0 0.5 10.3 0.0 4.6 5 0 0 5 5 5 2 AAA ATPase domain AAA_15 PF13175.1 EME85946.1 - 1.2e-05 24.6 3.8 0.44 9.5 0.0 4.6 5 1 0 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 EME85946.1 - 1.3e-05 24.9 0.0 0.045 13.6 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EME85946.1 - 2.7e-05 24.6 0.0 0.079 13.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EME85946.1 - 3.4e-05 24.1 0.3 0.17 12.1 0.0 3.6 4 0 0 4 4 2 1 AAA domain MobB PF03205.9 EME85946.1 - 4.6e-05 23.1 0.4 0.28 10.8 0.0 2.9 2 1 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EME85946.1 - 5.4e-05 22.9 0.0 0.09 12.4 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Arch_ATPase PF01637.13 EME85946.1 - 0.00011 22.0 0.0 0.18 11.4 0.0 3.3 3 0 0 3 3 2 1 Archaeal ATPase AAA_14 PF13173.1 EME85946.1 - 0.00012 22.0 0.0 0.58 10.0 0.0 3.7 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EME85946.1 - 0.00018 21.6 0.0 0.55 10.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EME85946.1 - 0.00024 21.0 0.0 0.92 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EME85946.1 - 0.00046 19.0 0.1 0.16 10.7 0.0 2.6 2 0 0 2 2 2 1 ArgK protein DUF87 PF01935.12 EME85946.1 - 0.00059 19.7 2.2 0.14 12.0 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_13 PF13166.1 EME85946.1 - 0.00069 18.2 10.7 0.65 8.3 0.0 4.9 4 1 0 4 4 4 2 AAA domain cobW PF02492.14 EME85946.1 - 0.0009 18.7 0.1 0.64 9.4 0.0 3.2 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF3385 PF11865.3 EME85946.1 - 0.0012 18.7 0.4 0.024 14.5 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) AAA_30 PF13604.1 EME85946.1 - 0.0013 18.3 0.0 2 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EME85946.1 - 0.0016 17.4 0.0 1.3 7.8 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein HEAT PF02985.17 EME85946.1 - 0.0018 18.1 1.5 1.5 9.0 0.0 4.3 4 0 0 4 4 3 1 HEAT repeat AAA_25 PF13481.1 EME85946.1 - 0.0019 17.6 0.0 2.8 7.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 EME85946.1 - 0.002 17.9 1.8 0.02 14.7 0.0 3.1 3 1 0 3 3 2 1 Dynamin family HEAT_EZ PF13513.1 EME85946.1 - 0.0028 18.1 1.2 8.6 6.9 0.0 4.8 5 1 1 6 6 3 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME85946.1 - 0.0035 17.6 0.5 0.37 11.2 0.0 3.4 3 1 1 4 4 3 1 Vacuolar 14 Fab1-binding region AAA_19 PF13245.1 EME85946.1 - 0.0052 16.5 0.0 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 EME85946.1 - 0.0062 16.1 0.0 4 6.9 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 EME85946.1 - 0.0065 15.9 0.0 0.92 8.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 EME85946.1 - 0.0068 15.4 0.4 1.7 7.6 0.0 3.2 3 0 0 3 3 3 1 Septin NB-ARC PF00931.17 EME85946.1 - 0.017 13.9 0.6 0.22 10.3 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain UPF0079 PF02367.12 EME85946.1 - 0.046 13.3 0.0 4 7.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EME85946.1 - 0.053 12.6 0.0 4.9 6.2 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EME85946.1 - 0.056 12.9 0.4 3 7.2 0.0 3.0 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 EME85946.1 - 0.08 12.6 0.0 13 5.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pinin_SDK_memA PF04696.8 EME85949.1 - 0.025 14.1 0.8 0.042 13.4 0.5 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Thioredoxin_8 PF13905.1 EME85950.1 - 0.069 13.2 0.0 17 5.6 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin PF00085.15 EME85950.1 - 0.071 12.7 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Methyltransf_12 PF08242.7 EME85952.1 - 3.7e-14 52.9 0.0 6.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME85952.1 - 7.3e-14 51.6 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME85952.1 - 1.3e-13 51.2 0.0 6e-13 49.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME85952.1 - 2.5e-13 50.5 0.0 3.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME85952.1 - 2.9e-13 49.8 0.0 3.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME85952.1 - 3.4e-08 33.7 0.0 7.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME85952.1 - 1.1e-06 27.9 0.0 5.4e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EME85952.1 - 1.4e-05 24.2 0.0 3e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EME85952.1 - 5.5e-05 22.5 0.0 0.00018 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EME85952.1 - 9.5e-05 22.1 0.0 0.00017 21.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EME85952.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EME85952.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EME85952.1 - 0.00015 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EME85952.1 - 0.0011 18.9 0.0 0.0045 17.0 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.7 EME85952.1 - 0.018 13.8 0.0 0.049 12.4 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase MetW PF07021.7 EME85952.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 EME85952.1 - 0.03 13.3 0.0 4.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF2999 PF11212.3 EME85952.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2999) NNMT_PNMT_TEMT PF01234.12 EME85952.1 - 0.13 11.1 0.1 12 4.7 0.0 3.0 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family Mito_carr PF00153.22 EME85953.1 - 2.3e-61 203.5 0.1 1.4e-19 69.6 0.1 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein CAP PF00188.21 EME85955.1 - 3e-17 63.2 2.4 3.6e-17 62.9 1.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mitovir_RNA_pol PF05919.6 EME85956.1 - 0.063 12.2 0.1 0.081 11.8 0.1 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase BCS1_N PF08740.6 EME85957.1 - 3.6e-29 101.7 0.1 6.8e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EME85957.1 - 3.4e-23 82.2 0.0 1.9e-22 79.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME85957.1 - 5.3e-06 25.6 0.0 9.1e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EME85957.1 - 2.4e-05 23.3 0.0 4.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EME85957.1 - 0.00035 21.3 0.0 0.0015 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME85957.1 - 0.0021 18.0 0.1 0.009 16.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME85957.1 - 0.0048 17.0 0.0 0.21 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EME85957.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EME85957.1 - 0.015 15.4 0.0 0.064 13.4 0.0 2.1 3 0 0 3 3 2 0 RNA helicase AAA_25 PF13481.1 EME85957.1 - 0.03 13.7 0.0 0.095 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME85957.1 - 0.036 13.9 0.0 0.097 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME85957.1 - 0.044 13.5 0.0 0.3 10.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EME85957.1 - 0.054 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ery_res_leader1 PF08051.6 EME85957.1 - 0.29 10.8 2.2 0.87 9.3 1.5 1.8 1 0 0 1 1 1 0 Erythromycin resistance leader peptide Acatn PF13000.2 EME85958.1 - 4.9e-151 503.9 24.9 3.3e-77 260.2 7.1 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Cyclase PF04199.8 EME85960.1 - 1.5e-17 63.7 0.1 1.7e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 EME85961.1 - 3.9e-92 309.1 26.5 4.7e-92 308.9 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME85961.1 - 3.4e-26 91.7 49.0 5.4e-23 81.2 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_LMP1 PF05297.6 EME85961.1 - 3.4 6.4 10.2 0.051 12.5 1.4 2.0 2 1 1 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) Aminotran_1_2 PF00155.16 EME85962.1 - 4.8e-59 200.1 0.0 6.3e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME85962.1 - 0.032 13.3 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Choline_sulf_C PF12411.3 EME85963.1 - 0.017 14.9 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Glucokinase PF02685.11 EME85963.1 - 0.056 12.2 0.0 0.056 12.2 0.0 1.0 1 0 0 1 1 1 0 Glucokinase GFA PF04828.9 EME85964.1 - 3.4e-12 46.1 1.7 4.6e-12 45.7 1.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme F-box PF00646.28 EME85965.1 - 0.0028 17.2 0.1 0.11 12.1 0.0 3.0 3 0 0 3 3 3 1 F-box domain SBDS_C PF09377.5 EME85966.1 - 9.2e-48 161.0 0.0 1.4e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EME85966.1 - 7.1e-28 96.2 0.2 1.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EME85966.1 - 0.036 13.7 0.1 0.85 9.3 0.0 2.5 2 1 0 2 2 2 0 Phage XkdN-like protein Peptidase_S10 PF00450.17 EME85967.1 - 2.8e-127 425.3 0.2 4.7e-127 424.5 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EME85967.1 - 5.7e-12 45.8 0.6 9.6e-12 45.0 0.4 1.3 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EME85967.1 - 0.0066 16.3 0.0 0.064 13.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1539 PF07560.6 EME85967.1 - 0.11 12.4 0.1 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Prefoldin PF02996.12 EME85967.1 - 0.14 11.8 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Prefoldin subunit DUF3450 PF11932.3 EME85967.1 - 0.2 10.8 2.8 0.28 10.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) F-box PF00646.28 EME85968.1 - 0.012 15.2 1.3 0.038 13.6 0.9 1.8 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.1 EME85968.1 - 0.015 15.0 1.8 0.071 12.8 0.0 2.7 2 1 1 3 3 3 0 F-box-like domain Cons_hypoth95 PF03602.10 EME85968.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.11 EME85970.1 - 9.7e-20 70.5 50.2 7.4e-18 64.3 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 2TM PF13239.1 EME85970.1 - 2.6 8.1 0.0 2.6 8.1 0.0 3.4 4 0 0 4 4 4 0 2TM domain DUF520 PF04461.8 EME85971.1 - 0.096 12.5 0.9 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF520) DrrA_P4M PF14860.1 EME85971.1 - 0.36 10.5 3.8 0.55 9.9 0.7 2.5 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain Ribosomal_S14 PF00253.16 EME85972.1 - 3.8e-16 58.2 1.9 9.5e-16 56.9 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e EthD PF07110.6 EME85973.1 - 0.0028 18.5 0.2 0.044 14.7 0.1 2.1 1 1 0 1 1 1 1 EthD domain FAD_binding_7 PF03441.9 EME85974.1 - 8.6e-78 261.3 0.3 1.3e-77 260.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME85974.1 - 9.3e-41 139.3 0.0 2.9e-40 137.7 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase SUR7 PF06687.7 EME85976.1 - 3.7e-28 98.5 6.6 5e-28 98.1 4.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family CoA_binding_3 PF13727.1 EME85976.1 - 0.004 17.0 0.2 0.0076 16.0 0.1 1.5 1 0 0 1 1 1 1 CoA-binding domain Pox_P21 PF05313.7 EME85976.1 - 0.01 15.1 0.6 0.01 15.1 0.4 1.6 2 0 0 2 2 2 0 Poxvirus P21 membrane protein FGE-sulfatase PF03781.11 EME85976.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 Myb_DNA-bind_6 PF13921.1 EME85977.1 - 5.2e-13 48.8 4.5 1.9e-05 24.6 0.8 4.6 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME85977.1 - 2.3e-09 37.1 1.1 1.9e-06 27.8 0.9 3.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain HTH_38 PF13936.1 EME85977.1 - 1.2e-07 31.0 0.9 0.012 15.1 0.0 3.8 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.1 EME85977.1 - 4.4e-05 22.9 0.5 14 5.4 0.1 4.9 4 0 0 4 4 4 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EME85977.1 - 0.0031 16.9 5.0 1.8 8.1 0.0 4.9 5 0 0 5 5 5 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EME85977.1 - 0.054 12.6 1.3 0.62 9.2 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EME85977.1 - 0.055 13.4 2.0 89 3.2 0.0 4.8 5 0 0 5 5 5 0 Helix-turn-helix domain DUF2089 PF09862.4 EME85977.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) PFU PF09070.6 EME85977.1 - 0.11 12.5 0.1 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) SURF1 PF02104.10 EME85978.1 - 1.8e-62 210.9 0.0 2.6e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 SURF1 family PCI PF01399.22 EME85979.1 - 1.1e-20 73.9 0.0 4.4e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 PCI domain Ku_PK_bind PF08785.6 EME85979.1 - 0.011 15.5 0.1 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 Ku C terminal domain like ERp29 PF07749.7 EME85979.1 - 0.23 12.1 3.6 0.24 12.0 0.0 2.9 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Macro PF01661.16 EME85980.1 - 1.7e-38 131.1 0.1 2.8e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Macro domain CENP-X PF09415.5 EME85981.1 - 4.5e-20 71.2 0.2 6e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Histone PF00125.19 EME85981.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Thioredoxin PF00085.15 EME85983.1 - 3e-63 210.0 0.2 1.8e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EME85983.1 - 3.9e-19 68.9 0.4 3.5e-08 33.6 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin-like domain ERp29 PF07749.7 EME85983.1 - 2.9e-18 66.2 0.1 1.1e-17 64.4 0.1 2.1 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_8 PF13905.1 EME85983.1 - 4.5e-13 49.1 0.2 2.3e-05 24.4 0.0 4.6 3 2 2 5 5 5 3 Thioredoxin-like Thioredoxin_7 PF13899.1 EME85983.1 - 1.9e-10 40.6 0.0 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EME85983.1 - 2.6e-07 30.2 0.0 0.00058 19.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EME85983.1 - 8.4e-07 28.9 0.4 0.4 10.4 0.0 3.7 3 1 1 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.16 EME85983.1 - 1.1e-06 28.3 0.1 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EME85983.1 - 4.8e-05 23.3 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EME85983.1 - 9.5e-05 22.1 0.0 0.2 11.4 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Redoxin PF08534.5 EME85983.1 - 0.00013 21.5 0.2 0.088 12.3 0.0 2.3 2 0 0 2 2 2 2 Redoxin TraF PF13728.1 EME85983.1 - 0.0014 18.2 0.0 0.76 9.2 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Glutaredoxin PF00462.19 EME85983.1 - 0.0051 16.7 1.4 4.8 7.2 0.2 3.2 2 2 0 2 2 2 2 Glutaredoxin DDE_Tnp_1_2 PF13586.1 EME85983.1 - 0.0054 16.8 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain Thioredoxin_4 PF13462.1 EME85983.1 - 0.013 15.4 2.0 2.2 8.2 0.0 3.6 3 1 1 4 4 4 0 Thioredoxin RE_HindIII PF09518.5 EME85983.1 - 0.02 13.8 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease HET PF06985.6 EME85984.1 - 7.1e-23 81.3 11.1 7.6e-21 74.7 2.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EME85985.1 - 5.2e-12 45.1 24.6 7.5e-06 24.8 8.9 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Peptidase_M24 PF00557.19 EME85986.1 - 2.7e-19 69.5 0.0 3.2e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RRF_GI PF12614.3 EME85986.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosome recycling factor Mob_synth_C PF06463.8 EME85987.1 - 2.9e-35 120.7 0.1 2e-34 118.0 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EME85987.1 - 5.7e-20 72.1 0.0 9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EME85987.1 - 1.7e-07 31.4 0.0 8.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EME85987.1 - 2.6e-06 27.4 0.0 9e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain DrsE PF02635.10 EME85987.1 - 0.13 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 DsrE/DsrF-like family DAO PF01266.19 EME85988.1 - 3e-66 223.7 0.1 4.4e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EME85988.1 - 3.3e-52 176.9 0.0 6e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME85988.1 - 3.3e-17 62.3 0.0 7.6e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox PF00070.22 EME85988.1 - 2.9e-05 24.3 0.3 0.0033 17.7 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EME85988.1 - 0.00018 21.3 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 EME85988.1 - 0.0002 20.3 0.3 0.00089 18.2 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EME85988.1 - 0.00041 20.4 0.0 0.00092 19.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME85988.1 - 0.00082 19.3 0.1 0.0075 16.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME85988.1 - 0.0016 18.3 0.5 0.0052 16.7 0.0 2.1 3 0 0 3 3 2 1 TrkA-N domain Trp_halogenase PF04820.9 EME85988.1 - 0.0026 16.4 0.6 0.058 12.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase SoxG PF04268.7 EME85988.1 - 0.0027 17.5 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family FAD_binding_3 PF01494.14 EME85988.1 - 0.0028 16.7 0.4 0.11 11.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EME85988.1 - 0.0044 16.8 0.1 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EME85988.1 - 0.011 15.7 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EME85988.1 - 0.028 13.5 0.1 0.13 11.3 0.0 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EME85988.1 - 0.031 12.7 0.0 0.56 8.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 EME85988.1 - 0.073 13.1 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase GMC_oxred_N PF00732.14 EME85988.1 - 0.086 11.9 0.1 0.79 8.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Ring_hydroxyl_A PF00848.14 EME85990.1 - 2.4e-35 122.0 4.9 2e-34 119.0 3.4 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EME85990.1 - 2.7e-14 52.4 0.0 5.9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain zf-C3HC4 PF00097.20 EME85995.1 - 6.2e-10 38.5 6.5 6.2e-10 38.5 4.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME85995.1 - 1.2e-09 37.8 7.6 1.2e-09 37.8 5.3 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME85995.1 - 3.3e-09 36.6 8.3 3.3e-09 36.6 5.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME85995.1 - 1.3e-06 27.9 9.6 3.4e-06 26.6 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME85995.1 - 1.9e-06 27.6 7.9 4.2e-06 26.5 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EME85995.1 - 5.7e-05 22.7 5.7 5.7e-05 22.7 4.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME85995.1 - 0.00032 20.3 1.2 0.00032 20.3 0.8 1.7 1 1 0 1 1 1 1 RING-type zinc-finger CopD PF05425.8 EME85995.1 - 0.0014 18.8 6.6 0.0014 18.8 4.6 3.7 4 0 0 4 4 4 1 Copper resistance protein D zf-rbx1 PF12678.2 EME85995.1 - 0.0014 18.7 7.2 0.0025 17.8 4.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EME85995.1 - 0.15 11.6 5.2 0.28 10.7 3.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1414 PF07208.6 EME85998.1 - 0.14 11.9 0.1 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) Atg14 PF10186.4 EME86001.1 - 2.4e-24 85.8 3.8 4e-24 85.0 2.6 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EME86001.1 - 0.00045 19.3 5.0 0.0015 17.6 3.5 1.7 1 1 0 1 1 1 1 Autophagy protein Apg6 BAR_2 PF10455.4 EME86001.1 - 0.012 14.6 2.3 0.022 13.6 1.6 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Macoilin PF09726.4 EME86001.1 - 0.015 13.6 9.9 0.022 13.0 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 EME86002.1 - 2.2e-39 135.1 28.0 2.2e-39 135.1 19.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86002.1 - 2.3e-15 56.1 6.5 2.3e-15 56.1 4.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter PEX11 PF05648.9 EME86003.1 - 7e-08 32.0 1.2 7e-08 32.0 0.9 2.6 3 0 0 3 3 3 1 Peroxisomal biogenesis factor 11 (PEX11) UQ_con PF00179.21 EME86004.1 - 5.2e-22 77.7 0.0 7.7e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME86004.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain Y_phosphatase3 PF13350.1 EME86006.1 - 7.5e-41 140.1 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EME86006.1 - 5.1e-09 36.1 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EME86006.1 - 0.0036 16.6 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EME86006.1 - 0.04 13.2 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-RING_2 PF13639.1 EME86008.1 - 9e-10 38.2 12.3 1.5e-09 37.4 8.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME86008.1 - 2.9e-06 27.1 10.7 4.9e-06 26.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME86008.1 - 4.4e-05 23.0 6.8 7.4e-05 22.3 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME86008.1 - 5.7e-05 22.6 10.4 9.5e-05 21.9 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME86008.1 - 0.00019 21.4 5.5 0.00037 20.5 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EME86008.1 - 0.00037 20.1 9.5 0.00065 19.3 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME86008.1 - 0.35 10.7 4.6 0.69 9.7 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EME86008.1 - 0.79 9.4 8.2 1.9 8.3 5.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EME86008.1 - 1.5 8.7 6.9 3.2 7.6 4.8 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING MutL_C PF08676.6 EME86010.1 - 8.5e-27 93.5 0.0 2e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EME86010.1 - 5e-22 77.5 0.5 5.2e-21 74.2 0.0 2.6 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EME86010.1 - 4.3e-14 52.3 1.3 9.4e-14 51.2 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EME86010.1 - 4.2e-13 48.9 0.0 1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rhodanese PF00581.15 EME86011.1 - 8.7e-20 71.1 0.0 9.6e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF442 PF04273.8 EME86011.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) DAO PF01266.19 EME86012.1 - 1.7e-47 162.0 0.5 2e-47 161.8 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME86012.1 - 1.1e-07 31.7 0.5 5.5e-07 29.5 0.0 2.4 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EME86012.1 - 1.7e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EME86012.1 - 0.00017 20.5 0.2 0.17 10.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EME86012.1 - 0.00023 21.1 0.2 0.063 13.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME86012.1 - 0.00042 19.4 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EME86012.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding adh_short PF00106.20 EME86012.1 - 0.0022 17.9 0.2 0.0096 15.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.13 EME86012.1 - 0.0037 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 EME86012.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME86012.1 - 0.01 15.6 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EME86012.1 - 0.013 14.3 0.0 3.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A KR PF08659.5 EME86012.1 - 0.014 15.0 0.0 0.037 13.6 0.0 1.7 1 0 0 1 1 1 0 KR domain GMC_oxred_N PF00732.14 EME86012.1 - 0.015 14.4 0.0 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.1 EME86012.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EME86012.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EME86012.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EME86012.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EME86012.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thi4 PF01946.12 EME86012.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pro-kuma_activ PF09286.6 EME86012.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain AA_permease PF00324.16 EME86013.1 - 1e-73 248.3 37.6 1.5e-73 247.8 26.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME86013.1 - 1.8e-22 79.5 41.6 3e-22 78.7 28.8 1.3 1 1 0 1 1 1 1 Amino acid permease DUF373 PF04123.8 EME86013.1 - 6.2 5.7 11.3 1.1 8.1 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF336 PF03928.9 EME86016.1 - 2.2e-21 76.0 0.0 2.8e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) BTB PF00651.26 EME86017.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain NFRKB_winged PF14465.1 EME86017.1 - 0.079 12.8 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like Mtc PF03820.12 EME86022.1 - 1.2e-105 352.5 1.7 6.8e-105 350.0 1.2 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier DUF963 PF06131.6 EME86022.1 - 0.24 10.7 2.3 0.69 9.2 0.4 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ELO PF01151.13 EME86027.1 - 7.5e-81 271.1 8.3 8.7e-81 270.8 5.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Asp PF00026.18 EME86028.1 - 0.00093 18.5 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EME86028.1 - 0.0065 15.7 3.5 0.0065 15.7 2.5 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EME86028.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VSP PF03302.8 EME86028.1 - 0.066 11.8 0.5 0.097 11.2 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein FixQ PF05545.6 EME86028.1 - 0.14 11.7 0.1 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glyco_hydro_28 PF00295.12 EME86029.1 - 8.3e-35 120.2 11.5 5.8e-32 110.9 6.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 DUF4598 PF15370.1 EME86030.1 - 6.4e-13 48.9 2.8 6.4e-13 48.9 1.9 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Porphobil_deam PF01379.15 EME86031.1 - 1.7e-82 275.5 0.1 2.3e-82 275.0 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EME86031.1 - 2.5e-19 69.1 0.1 4.8e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain IF4E PF01652.13 EME86032.1 - 3.8e-41 140.3 1.0 4.2e-41 140.2 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Carn_acyltransf PF00755.15 EME86033.1 - 6.8e-176 585.8 0.0 7.8e-176 585.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ldh_1_N PF00056.18 EME86034.1 - 2.1e-43 147.5 0.1 3.1e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EME86034.1 - 3.5e-42 144.0 0.0 5.8e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EME86034.1 - 0.00013 20.7 0.0 0.0002 20.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EME86034.1 - 0.0053 15.8 0.0 0.029 13.4 0.0 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 EME86034.1 - 0.086 13.1 0.3 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EME86035.1 - 0.025 13.6 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain LSM PF01423.17 EME86037.1 - 4.2e-16 58.2 0.0 6.2e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain Sec5 PF15469.1 EME86039.1 - 1.5e-38 132.3 0.5 8.2e-38 129.9 0.0 2.5 3 1 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 EME86039.1 - 1.1e-07 31.5 0.1 6.4e-07 29.1 0.0 2.4 1 0 0 1 1 1 1 Vps51/Vps67 DnaB PF00772.16 EME86039.1 - 0.061 13.2 0.7 0.22 11.4 0.2 2.2 2 0 0 2 2 2 0 DnaB-like helicase N terminal domain Iso_dh PF00180.15 EME86040.1 - 1.1e-98 330.4 0.0 1.3e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMG14_17 PF01101.13 EME86040.1 - 0.034 14.8 0.1 0.062 14.0 0.1 1.3 1 0 0 1 1 1 0 HMG14 and HMG17 Vps5 PF09325.5 EME86041.1 - 0.06 12.5 0.3 0.092 11.9 0.0 1.4 2 0 0 2 2 2 0 Vps5 C terminal like MFS_1 PF07690.11 EME86043.1 - 7.9e-13 47.8 10.9 1e-12 47.4 7.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.7 EME86043.1 - 4 6.7 9.8 4.2 6.6 4.7 2.5 2 1 1 3 3 3 0 5TMR of 5TMR-LYT UQ_con PF00179.21 EME86044.1 - 3.1e-37 127.1 0.0 3.5e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME86044.1 - 0.00028 20.6 0.0 0.00045 19.9 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EME86044.1 - 0.016 15.1 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.6 EME86044.1 - 0.064 12.7 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 PS_Dcarbxylase PF02666.10 EME86046.1 - 8.6e-35 119.8 0.0 1.3e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EME86046.1 - 0.074 12.7 0.1 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain FAD_binding_6 PF00970.19 EME86047.1 - 8.3e-05 22.6 0.0 0.0031 17.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EME86047.1 - 0.045 14.3 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Choline_kin_N PF04428.9 EME86047.1 - 0.14 11.6 0.1 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Choline kinase N terminus dCMP_cyt_deam_1 PF00383.17 EME86048.1 - 6.6e-06 25.7 0.2 1.8e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ORC5_C PF14630.1 EME86049.1 - 2.5e-50 171.4 0.0 3.5e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EME86049.1 - 6.6e-15 55.5 0.3 6.1e-14 52.4 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME86049.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME86049.1 - 0.0018 18.0 0.0 0.0066 16.1 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase Glyco_trans_1_4 PF13692.1 EME86049.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 AAA_14 PF13173.1 EME86049.1 - 0.086 12.7 0.0 0.28 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EME86049.1 - 0.14 11.1 0.0 9.8 5.0 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Suc_Fer-like PF06999.7 EME86050.1 - 4.1e-47 161.1 0.0 4.9e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like ECH PF00378.15 EME86051.1 - 4.1e-26 91.6 0.0 4.7e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family BTB PF00651.26 EME86052.1 - 1.2e-11 44.6 0.2 2.2e-10 40.5 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain PP28 PF10252.4 EME86052.1 - 0.066 13.2 3.0 0.14 12.1 2.1 1.5 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 MA3 PF02847.12 EME86052.1 - 0.094 12.4 0.1 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 MA3 domain NolV PF06635.7 EME86053.1 - 0.0032 16.6 0.3 0.007 15.5 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein NolV Sox_C_TAD PF12067.3 EME86053.1 - 0.054 13.6 0.0 0.069 13.3 0.0 1.2 1 0 0 1 1 1 0 Sox C-terminal transactivation domain DUF2360 PF10152.4 EME86053.1 - 3.6 7.8 7.2 50 4.1 5.0 2.1 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos PF00149.23 EME86054.1 - 4.8e-05 22.8 5.8 0.00029 20.3 4.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME86054.1 - 0.014 15.2 0.0 0.049 13.4 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF663 PF04950.7 EME86055.1 - 2.2e-93 312.4 0.0 2.2e-93 312.4 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EME86055.1 - 2.9e-26 90.7 0.0 9.4e-26 89.1 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EME86055.1 - 1.7e-06 27.6 0.0 0.00085 18.8 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EME86055.1 - 8e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME86055.1 - 9.5e-05 23.2 0.0 9.5e-05 23.2 0.0 4.4 3 1 0 3 3 1 1 AAA domain AAA_33 PF13671.1 EME86055.1 - 9.7e-05 22.2 0.0 0.00038 20.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME86055.1 - 0.00014 21.8 0.0 0.00014 21.8 0.0 2.3 3 0 0 3 3 1 1 AAA ATPase domain AAA PF00004.24 EME86055.1 - 0.00038 20.6 0.0 0.00091 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EME86055.1 - 0.0007 19.3 0.1 0.0018 17.9 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EME86055.1 - 0.00071 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EME86055.1 - 0.003 17.2 1.1 0.0051 16.5 0.2 1.8 2 0 0 2 2 1 1 Part of AAA domain NACHT PF05729.7 EME86055.1 - 0.0039 16.8 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EME86055.1 - 0.005 15.7 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Miro PF08477.8 EME86055.1 - 0.005 17.3 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EME86055.1 - 0.0056 15.4 0.0 0.013 14.2 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EME86055.1 - 0.0063 15.9 0.0 0.019 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME86055.1 - 0.01 16.1 0.0 0.01 16.1 0.0 4.4 5 1 1 6 6 3 0 AAA domain NTPase_1 PF03266.10 EME86055.1 - 0.014 15.0 0.3 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EME86055.1 - 0.015 14.7 0.1 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EME86055.1 - 0.019 15.2 0.0 0.019 15.2 0.0 2.4 3 0 0 3 3 1 0 ABC transporter RNA_helicase PF00910.17 EME86055.1 - 0.027 14.6 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 EME86055.1 - 0.036 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EME86055.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME86055.1 - 0.055 13.2 0.3 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EME86055.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.4 EME86055.1 - 0.078 12.4 0.0 0.63 9.5 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EME86055.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Inhibitor_I9 PF05922.11 EME86056.1 - 5.1e-06 26.9 0.2 6.1e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3186 PF11382.3 EME86056.1 - 0.03 13.4 0.2 0.032 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Clusterin PF01093.12 EME86058.1 - 0.019 13.7 0.9 0.02 13.6 0.6 1.0 1 0 0 1 1 1 0 Clusterin DUF3779 PF12621.3 EME86058.1 - 0.91 9.4 3.2 1.7 8.5 0.9 1.9 1 1 1 2 2 2 0 Phosphate metabolism protein Aldo_ket_red PF00248.16 EME86059.1 - 7.8e-62 208.6 0.2 8.9e-62 208.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EME86060.1 - 7.1e-23 80.8 39.0 9.7e-23 80.4 27.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4234 PF14018.1 EME86060.1 - 0.6 9.8 3.7 0.78 9.5 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) MFS_1_like PF12832.2 EME86060.1 - 1.5 8.6 7.4 0.15 11.8 1.3 2.4 2 0 0 2 2 2 0 MFS_1 like family Cutinase PF01083.17 EME86061.1 - 1.1e-26 93.7 0.9 1.5e-26 93.1 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EME86061.1 - 4.1e-05 23.1 0.1 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EME86061.1 - 0.0012 18.5 0.2 0.0015 18.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME86061.1 - 0.045 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Methyltransf_14 PF08484.6 EME86061.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Fungal_trans PF04082.13 EME86062.1 - 4.9e-07 28.8 3.9 1.6e-06 27.2 1.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 EME86063.1 - 9.3e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86063.1 - 3e-06 27.1 0.0 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86063.1 - 6.4e-05 22.6 0.0 0.0036 16.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Dynamin_N PF00350.18 EME86064.1 - 2.5e-43 147.7 0.0 5e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EME86064.1 - 6.1e-10 38.3 0.4 1.3e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Miro PF08477.8 EME86064.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Phostensin_N PF13916.1 EME86064.1 - 0.0097 15.8 0.1 0.03 14.3 0.1 1.9 1 0 0 1 1 1 1 PP1-regulatory protein, Phostensin N-terminal MMR_HSR1 PF01926.18 EME86064.1 - 0.034 14.0 0.0 0.094 12.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EME86064.1 - 0.17 11.8 0.1 0.17 11.8 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain U1snRNP70_N PF12220.3 EME86065.1 - 2.1e-28 98.4 4.8 3.1e-28 97.9 3.3 1.2 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EME86065.1 - 5.1e-16 58.0 0.0 7.7e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME86065.1 - 1.1e-15 57.3 0.0 2.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME86065.1 - 9.7e-07 28.5 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_31 PF01055.21 EME86066.1 - 3.1e-169 563.4 4.3 4e-169 563.1 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME86066.1 - 4.8e-08 32.7 0.4 1.6e-07 31.1 0.3 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Lectin_C PF00059.16 EME86067.1 - 0.0024 18.4 0.2 0.0068 17.0 0.1 1.7 1 0 0 1 1 1 1 Lectin C-type domain Myb_DNA-binding PF00249.26 EME86070.1 - 6.4e-27 93.3 2.5 8.1e-15 54.6 0.3 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EME86070.1 - 8.4e-20 70.6 0.7 8.1e-14 51.4 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.1 EME86070.1 - 0.0054 16.3 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Myb_DNA-bind_2 PF08914.6 EME86070.1 - 0.0067 16.2 0.1 0.069 12.9 0.1 2.3 1 1 1 2 2 2 1 Rap1 Myb domain Sigma70_r4_2 PF08281.7 EME86070.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2774 PF11242.3 EME86070.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_38 PF13936.1 EME86070.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain SLIDE PF09111.5 EME86070.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 SLIDE Myb_DNA-bind_5 PF13873.1 EME86070.1 - 0.53 10.2 4.9 13 5.7 0.0 3.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EME86070.1 - 1.5 8.9 5.0 5.2 7.2 0.6 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Glyco_transf_41 PF13844.1 EME86071.1 - 1.8e-100 336.1 0.0 5.7e-51 172.9 0.0 3.0 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EME86071.1 - 3e-26 90.8 12.3 1.4e-11 43.8 0.1 4.8 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EME86071.1 - 6e-24 82.6 8.1 4.7e-06 25.9 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME86071.1 - 3.6e-21 73.3 9.7 4.1e-05 23.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EME86071.1 - 1.7e-17 61.7 0.3 0.00059 19.4 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME86071.1 - 1.9e-16 59.0 4.0 0.0039 17.6 0.3 6.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EME86071.1 - 2e-16 59.6 6.1 2.7e-07 30.4 0.1 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EME86071.1 - 6.4e-15 54.0 2.8 0.012 15.7 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME86071.1 - 7.3e-14 51.8 7.7 5e-09 36.3 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME86071.1 - 7.5e-13 48.7 8.7 2.4e-06 28.0 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME86071.1 - 5.2e-12 44.6 1.2 0.21 11.4 0.0 5.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EME86071.1 - 6.7e-10 38.5 12.8 0.036 14.0 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME86071.1 - 4.9e-07 29.7 1.0 2.7 8.6 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.12 EME86071.1 - 2.3e-05 24.7 3.4 0.046 14.0 0.1 4.2 4 0 0 4 4 4 2 Bacterial transcriptional activator domain Apc3 PF12895.2 EME86071.1 - 0.00011 22.2 1.2 0.0097 16.0 0.1 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EME86071.1 - 0.001 18.2 0.7 0.18 10.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EME86071.1 - 0.0023 18.1 4.9 0.0056 16.9 1.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 EME86071.1 - 0.0033 17.4 0.9 0.38 10.7 0.1 2.9 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_9 PF13371.1 EME86071.1 - 0.0039 17.0 5.6 0.64 9.9 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME86071.1 - 0.072 12.9 0.0 0.33 10.8 0.0 2.1 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 EME86071.1 - 0.074 11.7 0.2 0.93 8.1 0.1 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 MIT PF04212.13 EME86071.1 - 0.11 12.3 4.5 14 5.6 0.0 4.0 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EME86071.1 - 0.16 12.6 3.6 0.37 11.5 0.7 3.1 3 0 0 3 3 2 0 Sel1 repeat Sulfate_transp PF00916.15 EME86073.1 - 7.4e-58 195.7 2.2 6.3e-57 192.7 0.2 2.3 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EME86073.1 - 6.1e-30 102.7 2.6 2e-29 101.0 1.8 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EME86073.1 - 2.1e-16 59.3 0.0 3.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EME86073.1 - 0.022 14.7 0.0 0.071 13.1 0.0 1.9 1 1 0 1 1 1 0 STAS domain Ribosomal_L11_N PF03946.9 EME86074.1 - 9.8e-18 63.3 0.0 1.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EME86074.1 - 7.9e-11 41.9 0.5 1.3e-10 41.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Peptidase_M43 PF05572.8 EME86075.1 - 4.5e-12 45.8 0.8 5.7e-12 45.4 0.1 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EME86075.1 - 1.2e-05 25.3 0.6 1.8e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EME86075.1 - 9.2e-05 22.9 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EME86075.1 - 0.0001 22.4 0.3 0.00015 21.8 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EME86075.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EME86075.1 - 0.016 14.1 1.1 0.028 13.2 0.1 1.7 2 0 0 2 2 2 0 Peptidase M66 Reprolysin_4 PF13583.1 EME86075.1 - 0.018 14.5 1.4 0.026 14.0 1.0 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-RING_2 PF13639.1 EME86077.1 - 3.4e-15 55.5 7.9 3.4e-15 55.5 5.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME86077.1 - 4.2e-11 42.3 9.3 1.3e-09 37.5 1.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME86077.1 - 8.4e-08 32.1 14.9 1.1e-07 31.7 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME86077.1 - 2e-07 30.5 15.6 5.1e-07 29.2 4.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EME86077.1 - 1.7e-06 27.8 11.6 6.8e-05 22.7 3.6 2.6 2 0 0 2 2 2 2 zinc-finger zf-RING_5 PF14634.1 EME86077.1 - 1.6e-05 24.5 5.0 1.6e-05 24.5 3.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EME86077.1 - 4.1e-05 23.5 10.1 4.1e-05 23.5 7.0 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME86077.1 - 0.0035 17.1 2.8 0.0035 17.1 1.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EME86077.1 - 0.0038 16.7 14.7 0.0096 15.4 3.2 2.3 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain HypA PF01155.14 EME86077.1 - 0.0053 16.4 0.6 0.0053 16.4 0.4 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 EME86077.1 - 0.014 15.1 11.8 0.4 10.4 0.2 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EME86077.1 - 0.02 14.7 13.6 0.28 11.0 3.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME86077.1 - 0.15 11.8 4.3 0.49 10.1 3.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EME86077.1 - 0.24 11.2 8.1 3.6 7.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.2 EME86077.1 - 0.81 9.5 9.2 0.54 10.1 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon FANCL_C PF11793.3 EME86077.1 - 1.4 8.9 11.7 0.55 10.2 4.7 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.24 EME86077.1 - 3.4 7.4 19.9 0.65 9.7 5.6 2.9 2 1 1 3 3 3 0 PHD-finger zinc-ribbons_6 PF07191.7 EME86077.1 - 6.4 6.6 11.6 0.36 10.6 0.9 2.6 2 1 0 2 2 2 0 zinc-ribbons CAP_N PF01213.14 EME86078.1 - 4e-78 262.8 13.7 2.8e-77 260.0 9.0 2.2 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EME86078.1 - 2.4e-54 183.0 2.3 3.2e-54 182.5 1.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EME86078.1 - 0.0024 17.2 2.8 0.071 12.5 0.7 2.3 1 1 1 2 2 2 2 Tubulin binding cofactor C PfkB PF00294.19 EME86079.1 - 3.1e-15 56.1 0.0 4.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UIM PF02809.15 EME86080.1 - 0.007 15.8 11.4 0.043 13.3 1.1 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif GFA PF04828.9 EME86084.1 - 2.6e-18 65.7 0.1 3.5e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3797 PF12677.2 EME86084.1 - 2.6 7.7 6.9 2.1 8.0 0.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF3797) SNF2_N PF00176.18 EME86085.1 - 3.3e-74 249.3 2.0 7.4e-74 248.2 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain SWIRM PF04433.12 EME86085.1 - 9.4e-35 118.6 0.1 3e-34 117.0 0.1 2.0 1 0 0 1 1 1 1 SWIRM domain Helicase_C PF00271.26 EME86085.1 - 4.1e-11 42.5 0.0 1.1e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-bind_6 PF13921.1 EME86085.1 - 0.01 15.9 0.1 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain ZZ PF00569.12 EME86085.1 - 0.015 14.7 8.3 0.14 11.7 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, ZZ type zf-C3HC4_2 PF13923.1 EME86085.1 - 2.1 8.4 8.1 0.26 11.3 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.18 EME86086.1 - 1.7e-34 117.0 0.9 2.3e-34 116.6 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EME86086.1 - 1.2e-25 88.8 13.1 2.6e-14 52.5 3.3 2.3 2 0 0 2 2 2 2 Ribosomal L40e family Rad60-SLD PF11976.3 EME86086.1 - 4.1e-18 64.8 0.4 6.4e-18 64.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EME86086.1 - 1.3e-05 25.3 0.1 5e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EME86086.1 - 0.0041 16.8 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EME86086.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME86086.1 - 0.018 15.2 0.0 0.019 15.1 0.0 1.2 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EME86086.1 - 0.095 12.7 0.1 0.25 11.3 0.0 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Palm_thioest PF02089.10 EME86087.1 - 2.1e-49 167.9 0.0 2.6e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 EME86087.1 - 0.016 14.5 0.0 0.07 12.4 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) SpoU_methylase PF00588.14 EME86088.1 - 5.9e-27 94.2 0.0 1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SPOUT_MTase_2 PF14419.1 EME86088.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP GTP_EFTU PF00009.22 EME86089.1 - 6.4e-61 205.0 0.2 8.8e-61 204.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME86089.1 - 6.9e-27 93.5 0.0 3.8e-26 91.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME86089.1 - 3.8e-18 65.3 2.6 4.3e-18 65.1 0.9 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME86089.1 - 3.1e-06 27.1 0.0 7.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME86089.1 - 0.0004 20.8 0.0 0.0008 19.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EME86089.1 - 0.0019 17.7 0.2 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EME86089.1 - 0.005 16.4 0.4 0.016 14.8 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.7 EME86089.1 - 0.077 12.1 0.1 0.27 10.3 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EME86089.1 - 0.13 11.5 0.9 3.5 6.8 0.6 2.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ECH_C PF13766.1 EME86090.1 - 5.5e-36 123.2 0.0 1.3e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EME86090.1 - 4.1e-26 91.6 0.0 7.9e-26 90.6 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family Meth_synt_2 PF01717.13 EME86091.1 - 1.4e-13 50.5 0.0 4e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EME86091.1 - 0.0025 17.1 0.1 0.1 11.8 0.0 2.9 3 1 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain SAF PF08666.7 EME86092.1 - 4.2e-10 39.8 0.0 7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 SAF domain NAD_binding_3 PF03447.11 EME86092.1 - 0.026 14.9 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain adh_short PF00106.20 EME86093.1 - 4.2e-13 49.5 0.0 7.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ACBP PF00887.14 EME86094.1 - 3e-25 87.6 0.0 5.3e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2036 PF09724.4 EME86094.1 - 0.024 13.7 0.8 0.035 13.2 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) DUF3474 PF11960.3 EME86094.1 - 0.04 13.9 0.1 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) TLV_coat PF00429.14 EME86094.1 - 0.48 8.8 1.6 0.8 8.0 1.1 1.3 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Atg14 PF10186.4 EME86094.1 - 1.9 7.3 6.2 0.42 9.4 0.6 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ResIII PF04851.10 EME86095.1 - 9.1e-21 74.5 0.0 3.1e-20 72.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME86095.1 - 1.3e-12 47.3 0.0 4.5e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EME86095.1 - 4.8e-12 45.6 0.0 3.1e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EME86095.1 - 0.017 15.2 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribonucleas_3_3 PF14622.1 EME86097.1 - 5e-06 26.4 0.0 0.0064 16.4 0.0 2.5 3 0 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.20 EME86097.1 - 4e-05 24.1 0.0 9.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EME86097.1 - 0.0006 20.2 0.0 0.0044 17.4 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease III domain KH_1 PF00013.24 EME86098.1 - 2.1e-26 91.2 3.9 9.8e-08 31.5 0.2 7.0 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EME86098.1 - 2.1e-21 75.0 8.3 0.00045 19.7 0.5 7.0 7 0 0 7 7 7 4 KH domain DUF1330 PF07045.6 EME86098.1 - 0.12 12.3 0.0 0.85 9.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1330) Actino_peptide PF14408.1 EME86099.1 - 2.7 7.9 9.0 1.7 8.5 0.1 3.5 4 0 0 4 4 4 0 Ribosomally synthesized peptide in actinomycetes HAD_2 PF13419.1 EME86100.1 - 1.6e-32 113.0 0.2 2e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME86100.1 - 9.2e-09 36.0 0.0 2.3e-08 34.7 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME86100.1 - 5e-07 29.3 0.0 9.4e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like BSP PF04450.7 EME86101.1 - 4.5e-68 228.7 0.0 5.4e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EME86101.1 - 5.8e-06 26.3 0.1 0.00063 19.7 0.0 2.2 1 1 1 2 2 2 2 Peptidase MA superfamily SprT-like PF10263.4 EME86101.1 - 0.0048 16.5 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 SprT-like family OprD PF03573.8 EME86101.1 - 0.008 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 outer membrane porin, OprD family TPR_11 PF13414.1 EME86101.1 - 0.014 14.9 0.8 0.06 13.0 0.0 2.3 3 0 0 3 3 3 0 TPR repeat Oxidored-like PF09791.4 EME86101.1 - 0.043 13.2 1.0 0.094 12.1 0.7 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal CLASP_N PF12348.3 EME86102.1 - 1.3e-119 397.5 5.1 6.9e-84 280.7 0.3 2.9 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EME86102.1 - 3.9e-05 23.3 4.7 0.63 10.2 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EME86102.1 - 0.11 13.0 3.6 3.7 8.1 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.1 EME86102.1 - 0.13 12.6 12.0 9.5 6.5 0.1 5.5 3 2 2 5 5 5 0 HEAT repeats Adaptin_N PF01602.15 EME86102.1 - 0.62 8.3 2.0 6.6 4.9 0.2 3.2 4 1 0 4 4 4 0 Adaptin N terminal region RhoGAP PF00620.22 EME86104.1 - 8.3e-45 152.1 0.0 2.2e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EME86104.1 - 2e-12 46.9 12.4 5.6e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 LIM domain Seryl_tRNA_N PF02403.17 EME86104.1 - 0.19 11.7 6.9 0.21 11.6 0.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 EME86104.1 - 1.4 6.6 1.2 2.2 6.0 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EME86104.1 - 2 8.2 11.1 3.6 7.3 0.5 3.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EME86104.1 - 2.6 7.7 17.1 0.055 13.2 4.8 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Vps52 PF04129.7 EME86105.1 - 3.6e-124 415.1 0.0 4.9e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Mer2 PF09074.5 EME86105.1 - 0.00079 19.4 0.2 0.00079 19.4 0.2 1.9 2 0 0 2 2 2 1 Mer2 Sec3_C PF09763.4 EME86105.1 - 0.0019 16.4 0.0 0.0031 15.7 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 BicD PF09730.4 EME86105.1 - 0.013 13.9 0.6 0.018 13.4 0.4 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D CCDC144C PF14915.1 EME86105.1 - 0.014 14.3 1.0 0.028 13.3 0.7 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region IncA PF04156.9 EME86105.1 - 0.019 14.5 1.9 0.071 12.7 1.3 1.9 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 EME86105.1 - 0.032 14.0 0.4 0.032 14.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Gp14 PF10666.4 EME86105.1 - 0.035 13.9 0.2 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Phage protein Gp14 Bet_v_1 PF00407.14 EME86105.1 - 0.058 13.0 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family CENP-F_leu_zip PF10473.4 EME86105.1 - 0.11 12.3 2.0 0.26 11.1 1.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 EME86105.1 - 0.13 12.1 2.5 3.1 7.6 0.4 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 EME86105.1 - 0.13 10.0 3.1 0.23 9.2 2.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-5a PF01287.15 EME86106.1 - 2.3e-26 91.5 0.5 3.4e-26 90.9 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EME86106.1 - 0.00017 21.1 0.6 0.00035 20.1 0.4 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EME86106.1 - 0.014 15.2 1.1 0.051 13.4 0.0 2.2 3 0 0 3 3 3 0 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EME86107.1 - 0.00012 21.4 1.5 0.0002 20.7 1.1 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 MFS_1 PF07690.11 EME86111.1 - 1.4e-31 109.5 28.7 1.4e-31 109.5 19.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DASH_Ask1 PF08655.5 EME86112.1 - 4.8e-33 112.7 0.2 7.3e-33 112.2 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 adh_short PF00106.20 EME86113.1 - 8.2e-31 107.1 1.1 1.1e-30 106.7 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86113.1 - 2.1e-22 80.0 1.1 2.5e-22 79.8 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86113.1 - 5.5e-13 48.9 0.1 1e-12 48.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME86113.1 - 6.7e-05 22.4 0.3 0.00019 20.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME86113.1 - 0.015 14.0 0.6 0.022 13.4 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EME86114.1 - 4.2e-43 147.4 26.6 4.2e-43 147.4 18.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86114.1 - 0.00052 18.7 13.4 0.00052 18.7 9.3 3.4 2 1 0 2 2 2 2 Sugar (and other) transporter PsbN PF02468.10 EME86114.1 - 0.72 9.5 3.8 0.97 9.0 0.5 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) PH PF00169.24 EME86115.1 - 2.8e-23 82.0 1.9 8.1e-11 42.0 0.2 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EME86115.1 - 3.6e-12 46.5 4.9 5.3e-05 23.4 0.1 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EME86115.1 - 1.1e-07 32.0 3.7 0.012 15.8 0.3 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EME86115.1 - 2.1e-06 27.5 1.6 0.00072 19.4 0.2 2.5 2 1 0 2 2 2 2 PH domain PH_8 PF15409.1 EME86115.1 - 2.7e-05 24.1 0.3 0.00032 20.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EME86115.1 - 0.0012 18.7 1.6 0.12 12.2 0.1 2.3 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology GTP_EFTU PF00009.22 EME86116.1 - 6.7e-54 182.1 0.0 1.4e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EME86116.1 - 6.2e-13 48.4 0.0 1.7e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME86116.1 - 6.2e-11 42.2 0.1 3.3e-10 39.9 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EME86116.1 - 8e-09 35.2 0.1 2.5e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.13 EME86116.1 - 0.00098 18.6 0.0 0.31 10.6 0.0 2.9 2 0 0 2 2 2 2 Elongation factor G, domain IV SET PF00856.23 EME86116.1 - 0.0014 18.9 1.3 0.033 14.5 0.1 2.8 3 0 0 3 3 3 1 SET domain MMR_HSR1 PF01926.18 EME86116.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DSPc PF00782.15 EME86117.1 - 3.7e-28 97.7 0.0 4.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EME86117.1 - 0.00019 21.5 0.0 0.00034 20.6 0.0 1.4 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EME86117.1 - 0.00044 20.5 0.1 0.0037 17.5 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EME86117.1 - 0.0021 17.0 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EME86117.1 - 0.0034 16.7 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Med11 PF10280.4 EME86119.1 - 0.02 14.9 1.0 0.043 13.8 0.7 1.5 1 0 0 1 1 1 0 Mediator complex protein RRM_1 PF00076.17 EME86120.1 - 2e-59 197.0 0.0 1e-20 73.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME86120.1 - 6.3e-45 151.0 0.0 3.2e-14 52.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME86120.1 - 2e-31 107.5 0.0 1e-10 41.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME86120.1 - 4.6e-07 29.5 0.0 0.049 13.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EME86120.1 - 0.0027 17.6 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EME86120.1 - 0.077 12.8 0.0 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Pyr_redox_3 PF13738.1 EME86121.1 - 1.7e-18 67.4 0.2 3.9e-18 66.2 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME86121.1 - 6.1e-16 57.7 0.0 4.3e-15 54.9 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME86121.1 - 2.4e-09 36.5 0.1 8.5e-08 31.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME86121.1 - 3.3e-08 33.6 2.4 3.1e-07 30.4 1.6 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME86121.1 - 4.2e-06 26.6 0.6 4.2e-06 26.6 0.4 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME86121.1 - 5.1e-05 23.6 6.2 0.05 14.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME86121.1 - 0.00012 21.1 1.5 0.00012 21.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EME86121.1 - 0.0003 20.8 0.1 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EME86121.1 - 0.0022 17.6 0.3 0.0041 16.7 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EME86121.1 - 0.047 13.9 0.2 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding GATase_5 PF13507.1 EME86121.1 - 0.071 12.0 0.1 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NAD_binding_9 PF13454.1 EME86121.1 - 0.078 12.7 1.4 0.72 9.6 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Spermine_synth PF01564.12 EME86121.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase Thi4 PF01946.12 EME86121.1 - 0.52 9.3 2.7 1.7 7.7 0.2 2.1 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EME86121.1 - 3 6.5 6.7 0.77 8.5 1.5 1.9 2 0 0 2 2 2 0 FAD binding domain E1-E2_ATPase PF00122.15 EME86123.1 - 9.7e-19 67.3 1.9 1.2e-18 67.0 0.0 2.1 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EME86123.1 - 2.4e-16 60.8 0.1 6.8e-15 56.0 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME86123.1 - 2e-14 54.1 0.0 3.8e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME86123.1 - 2.7e-12 46.4 0.0 8.5e-12 44.8 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME86123.1 - 0.00062 19.4 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3317 PF11779.3 EME86123.1 - 0.65 9.4 6.1 0.51 9.8 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) SurE PF01975.12 EME86124.1 - 1.8e-45 154.6 0.0 2.4e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE adh_short PF00106.20 EME86125.1 - 4.3e-27 95.0 0.3 7.1e-27 94.3 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86125.1 - 1e-23 84.3 0.1 1.2e-23 84.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86125.1 - 1.3e-14 54.2 0.2 2e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME86125.1 - 8.4e-05 22.1 0.4 0.0035 16.8 0.2 3.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EME86125.1 - 0.032 14.0 0.9 0.11 12.3 0.6 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PFU PF09070.6 EME86125.1 - 0.071 13.1 0.6 0.29 11.1 0.1 2.0 1 1 1 2 2 2 0 PFU (PLAA family ubiquitin binding) Cyclin_N PF00134.18 EME86126.1 - 1.3e-42 144.3 0.2 2.5e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME86126.1 - 4.7e-30 103.9 0.0 1.1e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EME86127.1 - 0.0007 19.4 11.5 0.0013 18.6 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCK PF07802.6 EME86127.1 - 0.13 12.4 0.4 0.26 11.4 0.3 1.4 1 0 0 1 1 1 0 GCK domain GFO_IDH_MocA PF01408.17 EME86128.1 - 2.9e-15 56.8 0.4 7.7e-14 52.2 0.3 2.3 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME86128.1 - 4e-05 23.3 0.0 0.00024 20.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sarcoglycan_2 PF05510.8 EME86128.1 - 0.05 11.8 0.0 0.069 11.4 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF2012 PF09430.5 EME86129.1 - 6.5e-28 97.0 0.0 8.4e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) Cyclin PF08613.6 EME86131.1 - 2.6e-28 99.3 0.0 4.5e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EME86131.1 - 2.1e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain HIT PF01230.18 EME86133.1 - 2.1e-15 57.0 0.0 5.5e-15 55.6 0.0 1.7 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EME86133.1 - 3.5e-15 56.2 0.6 1.7e-14 54.0 0.4 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4351 PF14261.1 EME86133.1 - 0.033 14.0 0.2 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DUF4211 PF13926.1 EME86134.1 - 1.1e-33 115.7 0.4 1.9e-33 115.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF972 PF06156.8 EME86135.1 - 0.066 13.5 2.0 0.12 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DMPK_coil PF08826.5 EME86135.1 - 0.54 10.1 5.8 0.12 12.2 1.0 2.2 3 0 0 3 3 3 0 DMPK coiled coil domain like Urm1 PF09138.6 EME86136.1 - 4.1e-34 116.5 0.0 4.5e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EME86136.1 - 8.3e-05 22.9 0.0 9.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 ThiS family WD40 PF00400.27 EME86137.1 - 1.4e-69 227.6 15.3 2.7e-08 33.3 0.0 11.7 11 0 0 11 11 11 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EME86137.1 - 0.00034 20.3 0.1 5.4 6.8 0.0 4.9 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region DUF4440 PF14534.1 EME86139.1 - 0.092 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) eIF-6 PF01912.13 EME86140.1 - 1.6e-82 275.4 0.8 2.3e-82 274.9 0.5 1.2 1 0 0 1 1 1 1 eIF-6 family HLH PF00010.21 EME86141.1 - 3.2e-12 45.9 0.3 6e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 EME86141.1 - 0.033 13.6 0.1 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein DUF3886 PF13025.1 EME86141.1 - 0.67 9.9 7.5 0.16 11.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) CRT10 PF08728.5 EME86143.1 - 0.037 12.0 1.7 0.039 11.9 1.2 1.0 1 0 0 1 1 1 0 CRT10 PGBA_C PF15437.1 EME86143.1 - 0.11 12.6 3.9 1.5 9.0 0.1 2.1 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal TraG-D_C PF12696.2 EME86143.1 - 0.41 10.5 3.3 0.54 10.1 2.3 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF4196 PF13846.1 EME86143.1 - 0.42 10.9 7.0 0.53 10.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) SPATIAL PF15256.1 EME86143.1 - 0.47 10.4 4.4 0.54 10.2 3.0 1.1 1 0 0 1 1 1 0 SPATIAL CytochromB561_N PF09786.4 EME86143.1 - 0.6 8.4 8.1 0.69 8.2 5.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Dicty_REP PF05086.7 EME86143.1 - 0.89 7.2 4.9 1 7.0 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4210 PF13915.1 EME86145.1 - 1.5e-26 92.4 0.1 2.7e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EME86145.1 - 2.3e-21 75.3 0.5 5.4e-21 74.2 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 EME86146.1 - 0.0011 18.8 39.0 0.013 15.3 5.0 2.5 2 1 1 3 3 3 2 rRNA processing Hex_IIIa PF02455.11 EME86146.1 - 3 6.4 7.7 3.6 6.1 5.3 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) p450 PF00067.17 EME86147.1 - 5.7e-68 229.5 0.0 8.4e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EME86148.1 - 1.3e-13 50.3 10.3 1.1e-07 30.7 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME86148.1 - 0.0017 17.1 11.1 0.014 14.0 3.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3679 PF12438.3 EME86148.1 - 0.35 10.2 4.6 0.66 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3679) DUF3980 PF13140.1 EME86148.1 - 0.73 10.1 4.1 2.6 8.4 2.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3980) adh_short PF00106.20 EME86149.1 - 4.3e-14 52.7 1.6 9.3e-14 51.6 0.4 2.0 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EME86149.1 - 0.00015 21.4 1.0 0.00032 20.4 0.2 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EME86149.1 - 0.061 12.2 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.14 EME86150.1 - 1.2e-11 44.2 0.3 0.0003 19.9 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EME86150.1 - 3.9e-06 26.7 0.1 1.1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME86150.1 - 3.6e-05 22.8 0.1 6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME86150.1 - 0.00019 20.4 0.1 0.0027 16.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME86150.1 - 0.00072 18.1 0.1 0.0036 15.8 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EME86150.1 - 0.0082 16.0 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME86150.1 - 0.0084 15.2 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME86150.1 - 0.012 15.7 0.0 0.09 12.8 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME86150.1 - 0.016 14.0 0.0 0.05 12.4 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EME86150.1 - 0.044 14.1 0.2 0.31 11.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME86150.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF4337 PF14235.1 EME86151.1 - 5.2 6.8 6.6 10 5.9 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Herpes_DNAp_acc PF04929.7 EME86151.1 - 8.8 5.1 8.4 13 4.6 5.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Gly-zipper_Omp PF13488.1 EME86152.1 - 0.00045 19.7 11.0 0.00052 19.6 7.1 1.5 1 1 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.10 EME86152.1 - 0.0012 18.4 18.8 0.002 17.7 13.0 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF533 PF04391.7 EME86152.1 - 0.011 15.0 0.7 0.018 14.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF1269 PF06897.7 EME86152.1 - 0.2 11.6 2.0 0.3 11.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_OmpA PF13436.1 EME86152.1 - 0.38 10.4 7.7 0.96 9.1 5.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Prefoldin_2 PF01920.15 EME86153.1 - 0.25 11.1 7.5 0.25 11.1 0.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF2894 PF11445.3 EME86153.1 - 1.8 8.7 6.3 0.91 9.7 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Tymo_45kd_70kd PF03251.8 EME86154.1 - 0.069 11.8 2.2 0.08 11.6 1.6 1.0 1 0 0 1 1 1 0 Tymovirus 45/70Kd protein DUF4608 PF15381.1 EME86154.1 - 0.55 10.4 5.8 0.055 13.6 0.9 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4608) Mhr1 PF12829.2 EME86155.1 - 2.5e-21 75.2 0.1 2.5e-21 75.2 0.1 2.4 2 1 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Glyco_hydro_2 PF00703.16 EME86156.1 - 5.9e-09 36.3 0.0 2.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EME86156.1 - 9.7e-06 25.2 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Fungal_trans PF04082.13 EME86157.1 - 1.7e-24 86.1 0.3 2.4e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86157.1 - 5e-07 29.5 7.9 8.3e-07 28.8 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME86158.1 - 9.1e-19 67.3 2.8 2.4e-12 46.1 0.1 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86158.1 - 2e-08 33.9 6.2 3.9e-08 33.0 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prp18 PF02840.10 EME86159.1 - 2.3e-50 170.1 0.1 2.3e-50 170.1 0.0 2.1 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EME86159.1 - 2.2e-07 29.9 3.0 2.2e-07 29.9 2.1 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 EME86159.1 - 6.3 5.9 22.3 10 5.2 15.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAP18 PF06487.7 EME86161.1 - 2e-30 105.0 0.0 2.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) F-box-like PF12937.2 EME86162.1 - 0.019 14.6 0.1 0.05 13.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF2672 PF10878.3 EME86162.1 - 0.046 13.4 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) F-box PF00646.28 EME86162.1 - 0.05 13.2 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain PSDC PF12588.3 EME86162.1 - 0.096 12.3 0.3 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Phophatidylserine decarboxylase Reo_sigmaC PF04582.7 EME86163.1 - 3.5e-06 26.4 17.8 0.0023 17.2 0.3 2.6 2 1 0 2 2 2 2 Reovirus sigma C capsid protein Spc7 PF08317.6 EME86163.1 - 0.00078 18.1 18.3 0.021 13.5 5.3 3.1 3 0 0 3 3 3 2 Spc7 kinetochore protein FlaC_arch PF05377.6 EME86163.1 - 0.0071 16.2 5.3 6.7 6.6 0.0 5.4 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 EME86163.1 - 0.0081 16.0 6.7 0.0081 16.0 4.7 3.4 3 1 0 3 3 2 1 FlxA-like protein DUF1351 PF07083.6 EME86163.1 - 0.014 15.0 3.8 0.014 15.0 2.7 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1351) DUF4618 PF15397.1 EME86163.1 - 0.019 14.3 15.6 0.023 14.0 4.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) IncA PF04156.9 EME86163.1 - 0.022 14.3 18.1 0.17 11.4 0.1 4.0 2 1 0 3 3 3 0 IncA protein MscS_porin PF12795.2 EME86163.1 - 0.046 13.0 19.1 1.4 8.1 9.1 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 EME86163.1 - 0.054 13.3 0.5 0.054 13.3 0.4 4.4 3 3 3 6 6 6 0 Protein of unknown function (DUF1664) YojJ PF10372.4 EME86163.1 - 0.065 13.0 0.5 0.065 13.0 0.3 2.5 3 0 0 3 3 2 0 Bacterial membrane-spanning protein N-terminus HCMV_UL139 PF12507.3 EME86163.1 - 0.3 11.2 5.6 4.8 7.3 0.5 3.5 3 1 1 4 4 4 0 Human Cytomegalovirus UL139 protein Bacillus_HBL PF05791.6 EME86163.1 - 0.35 10.2 18.0 2.5 7.4 0.1 4.2 2 2 3 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) FliD_C PF07195.7 EME86163.1 - 0.52 9.5 14.4 4.3 6.5 5.2 3.1 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus SlyX PF04102.7 EME86163.1 - 0.6 10.5 17.5 24 5.3 0.0 5.6 4 2 1 6 6 6 0 SlyX NPV_P10 PF05531.7 EME86163.1 - 0.64 10.3 16.1 6.1 7.1 3.9 4.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.1 EME86163.1 - 0.97 9.7 7.9 1.1 9.6 0.3 3.8 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin PF00804.20 EME86163.1 - 1.2 9.3 22.5 1.2 9.3 5.0 4.2 2 1 1 4 4 4 0 Syntaxin Baculo_PEP_C PF04513.7 EME86163.1 - 1.8 8.3 23.1 2.2 8.1 5.0 3.9 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EME86163.1 - 1.9 8.5 16.2 2.8 8.0 0.4 3.6 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family YlqD PF11068.3 EME86163.1 - 4.5 7.3 12.9 0.78 9.7 0.8 4.2 4 1 1 5 5 5 0 YlqD protein Allexi_40kDa PF05549.6 EME86163.1 - 4.8 6.3 14.1 1.7 7.8 4.1 3.1 2 1 1 3 3 3 0 Allexivirus 40kDa protein SPX PF03105.14 EME86163.1 - 6.3 6.4 14.6 39 3.8 10.1 2.1 1 1 0 1 1 1 0 SPX domain Jnk-SapK_ap_N PF09744.4 EME86163.1 - 6.9 6.6 13.9 0.16 11.9 2.3 3.2 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 T2SE_Nter PF05157.10 EME86166.1 - 0.057 13.4 0.0 0.067 13.2 0.0 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Rhomboid PF01694.17 EME86167.1 - 9.6e-36 122.9 9.9 9.6e-36 122.9 6.9 1.7 2 0 0 2 2 2 1 Rhomboid family Ribosomal_L18e PF00828.14 EME86168.1 - 3.7e-17 62.9 0.7 6.9e-17 62.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Glyco_transf_90 PF05686.7 EME86169.1 - 2.4e-15 56.1 2.8 1.8e-10 40.0 1.0 3.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Viral_cys_rich PF08008.7 EME86169.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Viral cysteine rich p450 PF00067.17 EME86170.1 - 0.0041 15.7 0.0 0.0049 15.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Trypan_PARP PF05887.6 EME86174.1 - 0.0032 17.2 0.2 0.0058 16.4 0.1 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Cyclin PF08613.6 EME86176.1 - 4.3e-15 56.4 0.1 9.5e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EME86176.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF605 PF04652.11 EME86177.1 - 0.62 9.4 13.2 0.74 9.1 9.2 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 EME86177.1 - 8.9 4.1 31.5 13 3.6 21.8 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pyr_redox_2 PF07992.9 EME86178.1 - 1.2e-26 93.8 0.0 4.1e-16 59.4 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME86178.1 - 1.5e-12 47.7 0.0 9.9e-11 41.9 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME86178.1 - 0.00038 20.5 0.1 1.3 9.0 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase PLDc_2 PF13091.1 EME86179.1 - 2.5e-13 49.8 0.0 4.3e-06 26.4 0.0 3.0 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EME86179.1 - 4.2e-10 39.1 9.1 4.4e-05 23.1 0.1 3.0 4 0 0 4 4 4 2 Phospholipase D Active site motif Phosducin PF02114.11 EME86180.1 - 4e-11 42.1 0.0 1.6e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Phosducin DUF1299 PF06975.6 EME86180.1 - 0.055 13.3 2.2 0.15 11.9 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) WD40 PF00400.27 EME86181.1 - 9.3e-52 171.1 17.7 2.1e-08 33.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EME86181.1 - 6e-05 22.8 0.0 0.023 14.4 0.0 2.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ribosomal_S14 PF00253.16 EME86182.1 - 1.4e-17 62.8 3.7 1.5e-17 62.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EME86182.1 - 0.016 14.9 0.8 0.02 14.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 EME86182.1 - 0.62 10.1 3.8 8.8 6.4 0.2 2.1 1 1 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4604 PF15377.1 EME86183.1 - 1.9e-18 67.1 13.2 2.4e-18 66.8 9.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Urocanase PF01175.13 EME86183.1 - 0.056 11.4 0.4 0.072 11.1 0.3 1.1 1 0 0 1 1 1 0 Urocanase AMP-binding PF00501.23 EME86184.1 - 2.2e-60 204.2 0.0 2.9e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RNA_pol_Rpc4 PF05132.9 EME86185.1 - 7.1e-27 93.9 0.1 7.1e-27 93.9 0.1 3.6 3 0 0 3 3 3 1 RNA polymerase III RPC4 YusW PF14039.1 EME86185.1 - 0.061 13.6 0.4 0.061 13.6 0.3 2.2 2 0 0 2 2 2 0 YusW-like protein Kinesin PF00225.18 EME86186.1 - 4.5e-112 374.0 0.2 6.4e-112 373.5 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain ERM PF00769.14 EME86186.1 - 0.00048 19.7 9.6 0.0011 18.5 6.6 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF904 PF06005.7 EME86186.1 - 0.0006 20.0 0.0 0.029 14.6 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF904) Mnd1 PF03962.10 EME86186.1 - 0.0029 17.2 6.2 0.0029 17.2 4.3 1.7 2 0 0 2 2 2 1 Mnd1 family TPR_MLP1_2 PF07926.7 EME86186.1 - 0.0096 15.6 13.4 0.0096 15.6 9.3 1.7 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein IMD PF08397.6 EME86186.1 - 0.049 12.9 4.3 0.092 12.0 3.0 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain HALZ PF02183.13 EME86186.1 - 0.049 13.3 1.2 0.14 11.9 0.8 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 EME86186.1 - 0.093 13.0 8.5 2.9 8.2 1.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) PAPS_reduct PF01507.14 EME86186.1 - 0.33 10.7 2.8 6.5 6.5 1.2 2.4 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Phage_GP20 PF06810.6 EME86186.1 - 0.46 9.9 9.6 0.088 12.2 3.7 2.0 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF87 PF01935.12 EME86186.1 - 1 9.1 7.5 0.6 9.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 EME86186.1 - 1.5 6.5 4.6 2.5 5.8 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EME86186.1 - 4.7 6.7 11.2 0.31 10.5 0.3 3.3 2 1 0 3 3 3 0 Septum formation initiator COX4 PF02936.9 EME86187.1 - 2e-46 157.2 0.0 2.3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV X PF00739.14 EME86187.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Trans-activation protein X DUF3106 PF11304.3 EME86187.1 - 0.64 10.4 5.4 0.11 12.8 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) NOA36 PF06524.7 EME86188.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NOA36 protein Cep57_CLD_2 PF14197.1 EME86188.1 - 0.33 10.9 11.4 0.093 12.6 4.9 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Peptidase_S10 PF00450.17 EME86189.1 - 1.7e-83 281.1 5.8 1.7e-83 281.1 4.0 2.2 2 1 0 2 2 2 1 Serine carboxypeptidase Gp_dh_C PF02800.15 EME86190.1 - 7.2e-74 246.4 0.0 1.1e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EME86190.1 - 7.1e-58 194.8 0.1 1.3e-57 194.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EME86190.1 - 0.04 13.8 0.2 0.41 10.5 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EME86190.1 - 0.091 11.9 0.1 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PUF PF00806.14 EME86192.1 - 3.4e-39 130.1 1.3 1.9e-06 26.9 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.6 EME86192.1 - 0.00021 21.9 0.0 0.0091 16.6 0.0 2.3 2 0 0 2 2 2 1 Regulator of ribonuclease activity B Avirulence PF03377.8 EME86192.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Peptidase_M1 PF01433.15 EME86193.1 - 3.5e-133 444.4 0.8 4.7e-133 444.0 0.5 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EME86193.1 - 6.3e-73 245.8 0.0 9.7e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EME86193.1 - 4e-21 75.3 3.3 7.2e-21 74.5 0.5 2.5 1 1 1 2 2 2 1 Peptidase MA superfamily BC10 PF06726.7 EME86194.1 - 1.2e-11 44.3 7.3 2.1e-11 43.6 5.0 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Dynamin_N PF00350.18 EME86195.1 - 4.7e-06 26.5 0.9 5.2e-05 23.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family DUF982 PF06169.7 EME86195.1 - 0.1 12.3 1.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF982) Baculo_PEP_C PF04513.7 EME86195.1 - 0.12 12.2 0.4 14 5.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EME86195.1 - 2.8 7.4 23.0 0.87 9.1 2.6 3.5 3 0 0 3 3 3 0 IncA protein Ras PF00071.17 EME86196.1 - 6.5e-62 207.6 0.1 7.6e-62 207.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME86196.1 - 4.5e-21 75.5 0.1 6.3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME86196.1 - 4.9e-13 48.6 0.0 5.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EME86196.1 - 2.3e-07 30.7 0.1 3.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EME86196.1 - 0.00038 20.6 0.1 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EME86196.1 - 0.00055 19.1 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME86196.1 - 0.00079 18.9 0.1 0.0031 16.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EME86196.1 - 0.0017 17.5 0.1 0.005 16.0 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EME86196.1 - 0.0023 17.0 0.0 0.0026 16.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EME86196.1 - 0.0054 16.6 0.1 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EME86196.1 - 0.018 15.3 0.1 0.032 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter DUF1128 PF06569.6 EME86196.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) SRPRB PF09439.5 EME86196.1 - 0.025 13.8 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EME86196.1 - 0.025 14.1 0.1 0.068 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME86196.1 - 0.026 14.5 0.3 0.047 13.6 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EME86196.1 - 0.029 13.6 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EME86196.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EME86196.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ssl1 PF04056.9 EME86197.1 - 1.9e-72 242.9 0.0 2.4e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EME86197.1 - 5.8e-19 67.8 10.6 5.8e-19 67.8 7.3 3.1 3 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 EME86197.1 - 1.2e-11 45.0 0.0 1.7e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EME86197.1 - 0.0043 16.3 2.1 0.01 15.1 1.4 1.6 1 0 0 1 1 1 1 Transcription factor Tfb4 FMN_dh PF01070.13 EME86198.1 - 3.4e-105 351.8 0.0 4.4e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EME86198.1 - 1.9e-20 72.4 0.0 3.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EME86198.1 - 8.4e-08 31.4 0.1 8.4e-05 21.6 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EME86198.1 - 2e-07 30.2 0.3 4.9e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase ATP11 PF06644.6 EME86198.1 - 0.0051 16.3 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 ATP11 protein NMO PF03060.10 EME86198.1 - 0.045 12.9 0.3 0.099 11.7 0.2 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 EME86198.1 - 0.087 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase cwf21 PF08312.7 EME86200.1 - 7.7e-19 67.2 6.9 7.7e-19 67.2 4.8 2.5 2 1 0 2 2 2 1 cwf21 domain Trans_reg_C PF00486.23 EME86200.1 - 0.16 11.9 0.8 2.6 8.0 0.5 2.3 1 1 0 1 1 1 0 Transcriptional regulatory protein, C terminal D123 PF07065.9 EME86201.1 - 1.6e-89 299.9 5.2 2.7e-87 292.6 1.6 2.1 1 1 1 2 2 2 2 D123 Raptor_N PF14538.1 EME86204.1 - 1.9e-60 203.1 0.0 3.4e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EME86204.1 - 1.5e-12 46.8 0.3 0.021 14.7 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 EME86204.1 - 6.2e-06 25.8 5.4 0.2 11.7 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat BBS2_Mid PF14783.1 EME86204.1 - 9.8e-05 22.1 1.7 0.0036 17.0 0.1 3.1 3 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 EME86204.1 - 0.00021 20.9 0.1 0.00048 19.8 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Peptidase_C14 PF00656.17 EME86204.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Cnd1 PF12717.2 EME86204.1 - 0.15 11.8 0.1 9 6.1 0.0 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CDP-OH_P_transf PF01066.16 EME86205.1 - 5.6e-14 52.2 2.3 5.6e-14 52.2 1.6 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase MFS_1 PF07690.11 EME86206.1 - 4e-26 91.5 15.0 9.9e-25 86.9 10.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86206.1 - 1.7e-19 69.7 13.2 9.9e-18 63.9 5.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1510 PF07423.6 EME86209.1 - 2.2 7.6 17.2 1.5 8.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF605 PF04652.11 EME86209.1 - 5 6.4 31.7 0.29 10.5 17.6 1.9 2 0 0 2 2 2 0 Vta1 like Complex1_LYR_1 PF13232.1 EME86210.1 - 7.3e-20 70.9 6.1 9.3e-20 70.6 4.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME86210.1 - 1.5e-18 66.3 5.2 2e-18 65.9 3.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EME86210.1 - 0.0013 19.1 1.0 0.0016 18.8 0.7 1.2 1 0 0 1 1 1 1 Complex1_LYR-like XdhC_CoxI PF02625.11 EME86211.1 - 0.024 14.2 1.6 0.034 13.7 1.1 1.2 1 0 0 1 1 1 0 XdhC and CoxI family OPT PF03169.10 EME86212.1 - 2.9e-172 574.3 52.5 3.3e-172 574.1 36.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Abhydrolase_3 PF07859.8 EME86213.1 - 8e-38 130.1 0.3 1e-37 129.7 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME86213.1 - 4.5e-06 26.7 0.5 7.6e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86213.1 - 7.8e-06 25.7 0.1 1.1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EME86213.1 - 2.2e-05 23.1 0.1 0.002 16.6 0.0 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 EME86213.1 - 9.9e-05 21.1 0.0 0.00013 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EME86213.1 - 0.00012 20.9 0.0 0.00016 20.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EME86213.1 - 0.018 14.2 0.4 0.044 13.0 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family HsbA PF12296.3 EME86214.1 - 6.1e-28 97.1 2.1 6.1e-28 97.1 1.4 1.8 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Sugar_tr PF00083.19 EME86215.1 - 1.2e-123 413.0 30.0 1.3e-123 412.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME86215.1 - 2.4e-28 98.9 55.1 3.7e-26 91.6 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EME86215.1 - 0.055 13.2 5.6 1.5 8.6 0.0 3.8 3 0 0 3 3 3 0 MFS_1 like family Meth_synt_2 PF01717.13 EME86216.1 - 2.9e-12 46.2 0.0 2.5e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EME86216.1 - 0.0027 17.0 0.0 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Toxin_51 PF15531.1 EME86217.1 - 0.13 12.0 0.0 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 51 Glyco_transf_15 PF01793.11 EME86218.1 - 1.4e-133 444.9 1.0 1.9e-133 444.5 0.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Apc13p PF05839.6 EME86219.1 - 1.7e-30 104.8 0.6 2e-30 104.6 0.4 1.0 1 0 0 1 1 1 1 Apc13p protein ADH_N PF08240.7 EME86220.1 - 3.8e-26 90.9 4.6 6.9e-26 90.1 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME86220.1 - 1.9e-18 66.2 0.2 4.2e-18 65.1 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME86220.1 - 0.00039 21.3 0.1 0.00077 20.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EME86220.1 - 0.032 13.7 0.2 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EME86220.1 - 0.084 12.0 0.3 0.15 11.2 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GET2 PF08690.5 EME86221.1 - 0.0087 15.3 1.4 0.0087 15.3 1.0 1.8 1 1 1 2 2 2 1 GET complex subunit GET2 mRNA_stabil PF13929.1 EME86221.1 - 0.022 13.7 0.2 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 mRNA stabilisation DUF1474 PF07342.6 EME86221.1 - 0.024 14.8 1.4 5 7.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) DndB PF14072.1 EME86221.1 - 0.027 13.6 0.9 0.034 13.2 0.6 1.1 1 0 0 1 1 1 0 DNA-sulfur modification-associated DUF3963 PF13124.1 EME86221.1 - 0.061 13.1 0.5 18 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) SPOC PF07744.8 EME86221.1 - 0.14 12.6 0.7 6.5 7.2 0.1 2.2 1 1 1 2 2 2 0 SPOC domain Rad60-SLD PF11976.3 EME86221.1 - 0.17 11.5 0.2 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like AATF-Che1 PF13339.1 EME86221.1 - 0.21 11.7 5.6 0.33 11.1 3.9 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TcdB_N PF12918.2 EME86221.1 - 0.43 10.7 4.8 5.8 7.0 0.4 2.2 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain Secretin_N_2 PF07655.8 EME86221.1 - 0.6 10.5 23.9 0.98 9.8 8.3 2.5 1 1 1 2 2 2 0 Secretin N-terminal domain Golgin_A5 PF09787.4 EME86221.1 - 1.4 7.3 9.0 1.7 7.1 6.3 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 TrbL PF04610.9 EME86221.1 - 1.4 8.5 5.4 2 8.0 2.9 1.8 1 1 2 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein Amidohydro_2 PF04909.9 EME86223.1 - 3.3e-38 131.8 0.4 4.5e-38 131.3 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EME86223.1 - 0.041 13.0 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 TatD related DNase DIOX_N PF14226.1 EME86224.1 - 9.2e-24 84.2 0.0 1.5e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME86224.1 - 5.8e-19 68.2 0.0 8.6e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRA_rpt PF07046.6 EME86224.1 - 0.036 14.0 1.3 0.17 11.9 0.2 2.4 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat LDB19 PF13002.2 EME86225.1 - 1.7e-39 135.3 0.1 4.5e-39 133.9 0.1 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 EME86225.1 - 1.1e-06 28.5 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain COMPASS-Shg1 PF05205.7 EME86226.1 - 9.1e-15 54.8 0.0 9.1e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0052 PF01933.13 EME86228.1 - 2e-52 178.4 0.0 2.5e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 YqzH PF14164.1 EME86228.1 - 0.11 12.3 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 YqzH-like protein GFO_IDH_MocA PF01408.17 EME86229.1 - 3.1e-23 82.5 0.0 4.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME86229.1 - 1.9e-13 50.2 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EME86229.1 - 0.0022 18.3 0.0 0.0037 17.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EME86229.1 - 0.052 13.4 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DNA_ligase_A_M PF01068.16 EME86230.1 - 5.2e-44 150.0 0.1 1.2e-43 148.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EME86230.1 - 1.1e-39 136.0 0.0 5.2e-39 133.8 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EME86230.1 - 2.9e-18 66.0 0.0 1.6e-17 63.6 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EME86230.1 - 5.6e-11 42.4 0.0 1.9e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 EME86230.1 - 0.078 12.7 0.1 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA ligase IV EF-hand_4 PF12763.2 EME86231.1 - 1.9e-07 30.7 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF2570 PF10828.3 EME86231.1 - 0.057 13.0 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Methyltransf_2 PF00891.13 EME86232.1 - 0.00015 21.0 2.1 0.00044 19.5 0.1 2.3 1 1 1 3 3 3 1 O-methyltransferase CheR PF01739.13 EME86232.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MOSC PF03473.12 EME86233.1 - 9.9e-19 67.1 0.0 2.1e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EME86233.1 - 3.4e-10 39.5 2.1 3.4e-10 39.5 1.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EME86233.1 - 0.00019 21.9 0.0 0.0004 20.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME86233.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.1 EME86233.1 - 0.027 14.2 1.1 0.15 11.8 0.7 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.9 EME86233.1 - 0.16 11.7 0.1 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 3-alpha domain NAD_binding_6 PF08030.7 EME86233.1 - 0.18 11.6 0.6 17 5.2 0.0 2.2 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Rep_fac-A_3 PF08661.6 EME86234.1 - 3.3e-25 88.0 0.1 3.8e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 PilP PF04351.8 EME86234.1 - 0.033 14.0 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Pilus assembly protein, PilP CbiJ PF02571.9 EME86234.1 - 0.073 12.3 0.1 0.1 11.8 0.1 1.3 1 1 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK GATase_4 PF13230.1 EME86235.1 - 5.4e-14 51.5 0.0 1.1e-10 40.7 0.0 3.1 2 1 1 3 3 3 3 Glutamine amidotransferases class-II GATase_6 PF13522.1 EME86235.1 - 1.6e-08 34.6 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EME86235.1 - 1.2e-05 24.1 0.0 3.7e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Fungal_trans PF04082.13 EME86236.1 - 2.3e-17 62.7 0.0 4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EME86236.1 - 4.7e-10 39.2 13.6 0.0001 22.3 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME86236.1 - 4.2e-06 26.7 20.3 6.1e-06 26.2 5.2 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME86236.1 - 0.0019 18.4 20.2 0.015 15.5 2.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger DUF1180 PF06679.7 EME86236.1 - 0.67 9.8 10.1 2.5 7.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) zf-C2H2_jaz PF12171.3 EME86236.1 - 1.4 9.1 3.7 0.5 10.5 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SRP9-21 PF05486.7 EME86237.1 - 2.9e-26 91.0 0.1 3.6e-26 90.7 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Peptidase_C70 PF12385.3 EME86237.1 - 0.052 13.2 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Abhydrolase_8 PF06259.7 EME86237.1 - 0.071 12.6 0.2 0.09 12.2 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF1308 PF07000.6 EME86238.1 - 6.3e-62 209.2 0.0 9.5e-62 208.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Pmp3 PF01679.12 EME86239.1 - 6.5e-20 70.5 9.6 9e-20 70.1 6.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PrgI PF12666.2 EME86239.1 - 0.01 15.9 0.2 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 PrgI family protein HCMVantigenic_N PF12154.3 EME86239.1 - 8.3 6.4 9.6 2 8.3 2.5 2.3 1 1 1 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Glyco_transf_8 PF01501.15 EME86240.1 - 2.7e-11 43.2 0.1 5.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Macoilin PF09726.4 EME86242.1 - 0.005 15.2 29.2 0.0082 14.4 20.2 1.3 1 0 0 1 1 1 1 Transmembrane protein DUF842 PF05811.8 EME86242.1 - 0.26 10.7 7.4 0.046 13.1 2.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Cupin_1 PF00190.17 EME86244.1 - 3.7e-07 29.6 0.0 5.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EME86244.1 - 1.4e-06 27.7 0.5 2.3e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EME86244.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.2 EME86244.1 - 0.0019 17.8 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EME86244.1 - 0.03 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Amidase PF01425.16 EME86245.1 - 2.3e-82 277.1 0.1 2.9e-82 276.8 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EME86245.1 - 2.1e-38 131.9 0.0 5.7e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 Isochorismatase family DIOX_N PF14226.1 EME86246.1 - 1.2e-25 90.3 0.1 1.8e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME86246.1 - 2.1e-13 50.3 0.0 4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.10 EME86247.1 - 3.9e-95 318.9 35.9 4.6e-95 318.7 24.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AAA PF00004.24 EME86248.1 - 7.8e-15 55.2 0.0 2.5e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EME86248.1 - 9.3e-05 22.1 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EME86248.1 - 0.0006 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EME86248.1 - 0.00066 20.4 0.5 0.0042 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME86248.1 - 0.00069 19.7 1.1 0.015 15.4 0.1 2.9 1 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EME86248.1 - 0.00097 19.1 0.2 0.0032 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EME86248.1 - 0.042 13.7 0.0 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EME86248.1 - 0.071 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EME86248.1 - 0.073 11.8 0.0 0.17 10.6 0.0 1.6 1 0 0 1 1 1 0 ArgK protein Fungal_trans PF04082.13 EME86251.1 - 3.7e-30 104.6 0.7 3.7e-30 104.6 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86251.1 - 6.7e-05 22.7 8.6 8e-05 22.4 5.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EME86253.1 - 2.9e-38 131.5 0.0 3.5e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME86253.1 - 0.0042 16.8 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EME86253.1 - 0.062 11.9 0.2 0.13 10.9 0.1 1.5 1 1 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.15 EME86253.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain HATPase_c PF02518.21 EME86254.1 - 4.7e-22 77.8 0.0 1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME86254.1 - 2.2e-19 69.5 0.8 5.8e-19 68.1 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EME86254.1 - 1.1e-11 44.5 1.2 1.9e-11 43.7 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EME86254.1 - 6.8e-05 22.8 0.0 0.00025 21.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EME86254.1 - 0.0072 16.3 1.1 0.098 12.7 0.0 2.8 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EME86254.1 - 0.033 14.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 PAS domain PAS_7 PF12860.2 EME86254.1 - 0.19 11.7 2.0 6.5 6.8 0.0 3.6 3 1 1 4 4 4 0 PAS fold Ribosomal_S6 PF01250.12 EME86256.1 - 7.5e-13 48.1 0.0 8.9e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.14 EME86257.1 - 5.8e-42 142.2 0.6 6.7e-42 142.0 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Cutinase PF01083.17 EME86258.1 - 2.3e-41 141.4 0.3 2.8e-41 141.2 0.2 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EME86258.1 - 0.0054 16.4 0.2 0.0064 16.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DIM PF08194.7 EME86258.1 - 0.068 13.1 0.2 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 DIM protein VirJ PF06057.6 EME86258.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cyanate_lyase PF02560.9 EME86259.1 - 2.7e-33 113.3 0.3 3.7e-33 112.8 0.2 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EME86259.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix zf-C2H2_4 PF13894.1 EME86260.1 - 1.3e-07 31.4 28.1 0.074 13.4 0.3 6.8 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EME86260.1 - 1.3e-06 28.3 30.9 0.057 13.7 1.0 7.0 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-met PF12874.2 EME86260.1 - 0.81 9.9 0.0 0.81 9.9 0.0 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Cupin_8 PF13621.1 EME86261.1 - 4.7e-62 209.7 0.0 6.1e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EME86261.1 - 0.00016 21.0 0.0 0.02 14.1 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein F-box-like PF12937.2 EME86262.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Amidohydro_1 PF01979.15 EME86263.1 - 5.3e-40 138.0 0.0 6.4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EME86263.1 - 4.8e-17 62.8 2.0 4.3e-16 59.7 1.4 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EME86263.1 - 9.1e-12 44.6 0.0 2.9e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EME86263.1 - 2e-10 40.4 2.1 1.3e-07 31.2 0.1 2.4 1 1 1 2 2 2 2 Amidohydrolase family Orbi_VP5 PF00901.12 EME86264.1 - 0.028 12.6 1.0 0.043 12.0 0.7 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF3439 PF11921.3 EME86264.1 - 0.055 13.2 11.7 0.12 12.1 6.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EME86264.1 - 2 6.0 4.5 3.2 5.3 3.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GAT PF03127.9 EME86265.1 - 3.4e-13 49.4 1.2 8.7e-13 48.1 0.8 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EME86265.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 VHS domain RNA_pol_Rpb6 PF01192.17 EME86265.1 - 0.063 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb6 Pyridoxal_deC PF00282.14 EME86266.1 - 2.2e-76 256.7 0.0 3.3e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans PF04082.13 EME86267.1 - 6.9e-23 80.8 0.0 1.2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86267.1 - 5.5e-08 32.5 12.9 1.3e-07 31.3 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A_deaminase PF00962.17 EME86268.1 - 2.5e-51 174.5 0.0 3e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Zn_clus PF00172.13 EME86270.1 - 1.6e-08 34.3 11.3 2.4e-08 33.7 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME86270.1 - 2e-05 23.3 5.2 2.7e-05 22.9 3.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 EME86272.1 - 5.4e-94 315.5 0.0 6.5e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Amidase HMGL-like PF00682.14 EME86273.1 - 1.6e-63 214.5 0.0 2.9e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EME86273.1 - 4.1e-20 71.9 0.1 1e-19 70.6 0.1 1.7 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain UPF0146 PF03686.8 EME86273.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 4HBT_3 PF13622.1 EME86274.1 - 6.8e-52 176.7 0.0 1.6e-51 175.5 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EME86274.1 - 8.7e-27 93.3 0.0 3e-12 46.3 0.0 4.2 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.17 EME86274.1 - 0.0019 18.3 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 Thioesterase superfamily DASH_Dad2 PF08654.5 EME86274.1 - 0.016 15.2 0.3 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 N2227 PF07942.7 EME86276.1 - 6.6e-93 310.5 0.0 8.4e-93 310.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EME86276.1 - 3.4e-05 23.6 0.0 7.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME86276.1 - 0.04 14.4 0.0 0.88 10.0 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain 7TMR-HDED PF07697.6 EME86276.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 7TM-HD extracellular Vma12 PF11712.3 EME86277.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.7 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Exo_endo_phos PF03372.18 EME86278.1 - 4.2e-12 46.5 0.3 5.3e-12 46.1 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EME86278.1 - 2.5e-06 27.0 0.0 6.5e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Aminotran_3 PF00202.16 EME86279.1 - 1.4e-78 264.1 0.0 1.9e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EME86279.1 - 0.079 11.9 0.0 0.34 9.8 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II SRP19 PF01922.12 EME86280.1 - 6.7e-26 90.7 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.20 EME86281.1 - 0.0024 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME86281.1 - 0.0053 15.8 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBX PF00789.15 EME86282.1 - 5.7e-14 51.9 0.0 1.7e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EME86282.1 - 1.2e-10 40.7 1.7 1.7e-10 40.2 0.5 1.8 2 0 0 2 2 2 1 UBA-like domain CAF-1_p150 PF11600.3 EME86282.1 - 0.0026 17.1 17.2 0.0052 16.2 11.9 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4424 PF14415.1 EME86282.1 - 0.011 15.2 0.6 0.017 14.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) Med19 PF10278.4 EME86282.1 - 0.24 11.0 5.8 0.38 10.4 4.0 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC45 PF02724.9 EME86282.1 - 0.91 7.4 8.4 1.2 7.0 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 EME86282.1 - 2.5 7.4 11.6 4 6.8 8.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 EME86282.1 - 2.7 7.7 10.2 4.4 7.0 7.0 1.3 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 EME86282.1 - 6.1 5.9 11.5 12 4.9 8.0 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Phytase-like PF13449.1 EME86283.1 - 5.9e-28 98.0 0.0 1e-27 97.3 0.0 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase APC10 PF03256.11 EME86287.1 - 2.1e-45 154.7 0.0 2.3e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) BCNT PF07572.7 EME86288.1 - 1.9e-15 56.5 0.9 1.9e-15 56.5 0.6 2.0 2 0 0 2 2 2 1 Bucentaur or craniofacial development CDP-OH_P_transf PF01066.16 EME86289.1 - 1.9e-16 60.2 4.6 1.9e-16 60.2 3.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NDUF_B4 PF07225.7 EME86291.1 - 0.011 15.5 0.1 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GST_N PF02798.15 EME86292.1 - 3.9e-09 36.5 0.0 8.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EME86292.1 - 9.7e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME86292.1 - 1.9e-05 24.5 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME86292.1 - 9.4e-05 22.2 0.0 0.00034 20.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME86292.1 - 0.0003 21.2 0.0 0.00052 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME86292.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.17 EME86293.1 - 4.1e-07 30.1 0.1 0.003 17.7 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EME86293.1 - 0.02 14.8 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Mg_trans_NIPA PF05653.9 EME86295.1 - 1.3e-104 349.4 13.5 1.5e-104 349.2 9.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EME86295.1 - 1.7e-06 28.2 4.4 1.7e-06 28.2 3.1 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EME86295.1 - 7.3e-05 22.8 7.5 7.3e-05 22.8 5.2 3.2 2 1 0 2 2 2 1 EamA-like transporter family NfeD PF01957.13 EME86295.1 - 1.9 8.6 13.4 0.92 9.6 0.1 3.2 1 1 3 4 4 4 0 NfeD-like C-terminal, partner-binding AAA_2 PF07724.9 EME86297.1 - 9.4e-47 159.1 0.0 2.9e-45 154.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EME86297.1 - 5.4e-27 94.5 0.0 3e-14 53.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME86297.1 - 6.2e-16 58.9 17.1 1.9e-06 28.0 0.0 6.4 3 2 4 7 7 6 2 AAA ATPase domain ClpB_D2-small PF10431.4 EME86297.1 - 7.5e-16 57.8 0.0 2.9e-15 55.9 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EME86297.1 - 3.1e-15 56.1 0.2 1.4e-09 37.8 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME86297.1 - 2.3e-14 53.6 0.1 2.2e-05 24.5 0.0 4.1 2 2 1 3 3 3 2 AAA domain Clp_N PF02861.15 EME86297.1 - 2.4e-10 40.1 3.4 0.0037 17.1 0.0 4.0 3 0 0 3 3 3 2 Clp amino terminal domain AAA_17 PF13207.1 EME86297.1 - 1.7e-08 35.2 5.9 0.011 16.6 0.0 4.0 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EME86297.1 - 2.6e-08 33.5 0.0 2.7e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EME86297.1 - 5.2e-07 29.3 2.2 0.012 15.3 0.1 3.2 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 EME86297.1 - 8.3e-07 28.5 0.0 0.036 13.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EME86297.1 - 8.6e-06 26.0 5.7 0.031 14.5 0.0 3.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EME86297.1 - 1.8e-05 24.0 0.2 0.096 11.8 0.0 3.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EME86297.1 - 2.1e-05 24.3 9.0 0.011 15.4 0.1 4.9 5 2 1 6 6 4 1 Archaeal ATPase AAA_33 PF13671.1 EME86297.1 - 4.2e-05 23.4 0.0 0.2 11.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EME86297.1 - 5.1e-05 22.3 0.5 0.0056 15.6 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EME86297.1 - 5.5e-05 23.3 0.0 0.45 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EME86297.1 - 0.0001 21.9 0.0 0.6 9.8 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EME86297.1 - 0.00015 21.8 3.7 0.34 10.8 0.0 3.8 3 1 0 3 3 2 2 AAA domain AAA_3 PF07726.6 EME86297.1 - 0.00019 21.0 0.0 0.9 9.1 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EME86297.1 - 0.00044 20.1 0.2 0.69 9.7 0.0 4.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EME86297.1 - 0.00047 19.6 2.8 1.3 8.3 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_24 PF13479.1 EME86297.1 - 0.00078 19.0 0.0 0.53 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EME86297.1 - 0.0011 19.2 2.2 0.82 9.9 0.0 3.6 4 0 0 4 4 3 1 ABC transporter DUF258 PF03193.11 EME86297.1 - 0.0014 17.8 0.0 0.73 9.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME86297.1 - 0.0016 17.9 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 EME86297.1 - 0.0044 16.7 0.1 0.2 11.3 0.0 3.0 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 EME86297.1 - 0.0046 16.6 0.0 0.47 10.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EME86297.1 - 0.0065 15.9 0.0 1.4 8.2 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Torsin PF06309.6 EME86297.1 - 0.0072 16.2 0.0 0.031 14.1 0.0 2.0 2 0 0 2 2 1 1 Torsin AAA_21 PF13304.1 EME86297.1 - 0.022 14.7 0.0 2.2 8.1 0.0 3.0 4 0 0 4 4 2 0 AAA domain MMR_HSR1 PF01926.18 EME86297.1 - 0.041 13.8 0.1 4.3 7.3 0.0 3.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase TPR_14 PF13428.1 EME86297.1 - 0.043 14.4 6.4 0.63 10.8 0.1 3.9 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_10 PF12846.2 EME86297.1 - 0.043 13.2 10.8 0.44 9.9 0.1 5.3 5 1 0 5 5 5 0 AAA-like domain UPF0079 PF02367.12 EME86297.1 - 0.046 13.3 0.0 15 5.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 V_ATPase_I PF01496.14 EME86297.1 - 0.21 9.4 8.9 0.41 8.4 6.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EME86297.1 - 2.3 8.4 0.0 2.3 8.4 0.0 5.1 3 2 1 4 4 3 0 AAA domain Pkinase PF00069.20 EME86298.1 - 3.2e-48 164.1 0.0 3.1e-45 154.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME86298.1 - 4.5e-30 104.5 0.0 1.2e-28 99.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EME86298.1 - 0.00062 18.8 0.0 0.00094 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME86298.1 - 0.005 16.6 0.1 0.39 10.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EME86298.1 - 0.0083 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EME86298.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 EME86299.1 - 1.7e-42 145.0 6.0 4.8e-42 143.6 4.1 1.6 1 1 0 1 1 1 1 Membrane transport protein DUF3125 PF11323.3 EME86299.1 - 0.0073 16.0 1.4 0.019 14.7 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3125) DUF2985 PF11204.3 EME86300.1 - 3.9e-26 90.6 3.2 7.9e-26 89.6 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF4181 PF13789.1 EME86300.1 - 0.09 12.7 1.6 0.18 11.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Aldo_ket_red PF00248.16 EME86302.1 - 1.7e-47 161.6 0.0 2.3e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 EME86303.1 - 1.3e-30 104.9 7.7 1.2e-13 50.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EME86304.1 - 9.5e-102 340.3 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase RRM_1 PF00076.17 EME86305.1 - 5.3e-06 25.9 0.0 9.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME86305.1 - 5.4e-06 26.1 0.1 9.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME86305.1 - 4e-05 23.5 0.0 7.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EME86305.1 - 0.0042 17.2 0.0 0.014 15.6 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. UPF0061 PF02696.9 EME86307.1 - 4.8e-122 407.7 0.0 6e-122 407.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Meth_synt_2 PF01717.13 EME86310.1 - 2.1e-24 86.1 0.0 1.9e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EME86310.1 - 5e-08 32.5 0.0 0.0013 18.0 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain An_peroxidase PF03098.10 EME86310.1 - 0.091 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Animal haem peroxidase FA_desaturase PF00487.19 EME86311.1 - 1e-24 87.3 16.7 1.5e-24 86.8 11.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EME86311.1 - 2.4e-06 27.6 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) XRCC4 PF06632.7 EME86313.1 - 7.2e-05 21.7 10.1 0.00015 20.7 6.9 1.5 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Alk_phosphatase PF00245.15 EME86315.1 - 6e-67 226.1 0.2 1.2e-66 225.1 0.2 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EME86315.1 - 7.3e-07 28.8 0.8 1.4e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME86315.1 - 1.2e-06 28.0 3.8 5.2e-05 22.5 2.6 2.5 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EME86315.1 - 0.0083 14.5 0.1 0.012 14.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Abhydrolase_5 PF12695.2 EME86316.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME86316.1 - 2.8e-06 26.7 0.0 4.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EME86316.1 - 0.0022 17.4 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EME86316.1 - 0.011 15.1 0.0 0.1 12.0 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase TPT PF03151.11 EME86317.1 - 3.1e-38 130.8 0.9 3.1e-38 130.8 0.6 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EME86317.1 - 1.7e-14 53.4 10.1 2.6e-14 52.8 7.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME86317.1 - 5.7e-08 32.8 24.3 0.0004 20.4 5.4 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EME86317.1 - 0.012 14.4 1.3 0.017 13.9 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Fringe PF02434.11 EME86318.1 - 9.2e-05 21.7 0.5 0.0032 16.7 0.3 2.5 2 1 0 2 2 2 1 Fringe-like PAN_2 PF08276.6 EME86318.1 - 0.0057 16.4 0.6 0.012 15.4 0.4 1.4 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.21 EME86318.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.7 EME86318.1 - 0.023 14.1 2.0 0.039 13.4 1.4 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family PAN_4 PF14295.1 EME86318.1 - 0.025 14.2 1.9 0.051 13.2 1.3 1.4 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 EME86318.1 - 0.064 12.8 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 PAN-like domain Pirin PF02678.11 EME86319.1 - 1.1e-26 92.7 0.3 1.9e-26 91.9 0.2 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EME86319.1 - 0.0014 18.0 4.8 0.0021 17.5 0.3 2.8 3 1 0 3 3 3 1 Cupin domain Acyl-CoA_dh_2 PF08028.6 EME86320.1 - 0.25 11.6 3.3 0.32 11.2 1.7 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ATXN-1_C PF12547.3 EME86320.1 - 0.41 10.6 3.7 0.84 9.6 1.0 2.3 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator adh_short PF00106.20 EME86321.1 - 1.7e-23 83.3 1.6 1.4e-22 80.3 1.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86321.1 - 5.4e-11 42.7 0.0 4.5e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86321.1 - 6.3e-07 29.2 0.3 6.3e-07 29.2 0.2 2.1 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EME86321.1 - 0.02 14.9 0.2 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 NADH(P)-binding Lysozyme_like PF13702.1 EME86323.1 - 0.0027 17.1 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Lysozyme-like SLT PF01464.15 EME86323.1 - 0.025 14.0 0.3 0.1 12.1 0.2 1.9 1 1 0 1 1 1 0 Transglycosylase SLT domain SLT_2 PF13406.1 EME86323.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain PHD PF00628.24 EME86324.1 - 7.7e-07 28.7 9.2 1.2e-06 28.0 6.3 1.3 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EME86324.1 - 4.9e-05 23.4 2.5 6.8e-05 23.0 1.7 1.3 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx zf-PHD-like PF15446.1 EME86324.1 - 0.11 11.7 7.1 0.074 12.3 3.6 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 EME86324.1 - 7 6.8 11.8 1.1 9.3 5.6 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 EME86324.1 - 8.5 6.1 12.6 1.2 8.8 5.4 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MFS_1 PF07690.11 EME86325.1 - 3.6e-37 127.8 42.8 3.6e-37 127.8 29.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86325.1 - 3e-17 62.3 8.3 3e-17 62.3 5.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EME86325.1 - 0.021 12.8 8.2 0.018 13.1 2.7 2.7 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Prefoldin_2 PF01920.15 EME86326.1 - 1e-23 83.0 2.8 1.4e-23 82.6 2.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Tektin PF03148.9 EME86326.1 - 0.029 12.9 0.7 0.029 12.9 0.5 2.0 1 1 1 2 2 2 0 Tektin family DivIVA PF05103.8 EME86326.1 - 0.098 12.7 0.1 0.098 12.7 0.0 2.2 2 0 0 2 2 2 0 DivIVA protein PspA_IM30 PF04012.7 EME86326.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.2 2 1 0 2 2 2 0 PspA/IM30 family E2 PF08199.6 EME86326.1 - 0.35 10.4 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage E2-like protein Mnd1 PF03962.10 EME86326.1 - 0.79 9.3 10.7 3.1 7.3 4.7 2.0 2 0 0 2 2 2 0 Mnd1 family DivIC PF04977.10 EME86326.1 - 1.1 8.7 10.3 5.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 EME86326.1 - 1.3 9.0 12.9 0.7 9.9 0.2 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FTA4 PF13093.1 EME86326.1 - 2.9 7.2 7.6 5.4 6.3 5.2 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4164 PF13747.1 EME86326.1 - 9.8 6.3 12.9 3.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DAO PF01266.19 EME86329.1 - 2.2e-47 161.6 0.0 3.5e-47 161.0 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME86329.1 - 1.1e-05 25.4 0.1 0.0024 17.7 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME86329.1 - 1.6e-05 25.0 0.1 0.0014 18.7 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME86329.1 - 4e-05 23.5 0.0 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME86329.1 - 6.8e-05 22.6 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME86329.1 - 0.00047 19.1 0.0 0.069 12.0 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Shikimate_DH PF01488.15 EME86329.1 - 0.001 19.2 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EME86329.1 - 0.013 14.3 0.1 0.08 11.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.13 EME86329.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EME86329.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAM-associated PF14303.1 EME86330.1 - 0.0015 18.8 10.1 0.0027 18.0 7.0 1.5 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Parvo_coat PF00740.13 EME86330.1 - 0.63 8.9 2.8 0.75 8.6 1.9 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CAF-1_p150 PF11600.3 EME86330.1 - 3.9 6.7 32.5 6.9 5.9 22.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Methyltransf_23 PF13489.1 EME86331.1 - 9.4e-14 51.4 0.0 1.4e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME86331.1 - 3.1e-10 40.3 0.0 8.1e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME86331.1 - 5.2e-09 35.8 0.0 6e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME86331.1 - 2e-07 31.5 0.0 3.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME86331.1 - 5.4e-07 30.0 0.0 9.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME86331.1 - 1.6e-06 27.3 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME86331.1 - 0.0017 18.6 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME86331.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EME86331.1 - 0.075 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cep57_CLD_2 PF14197.1 EME86332.1 - 0.00032 20.5 0.5 0.00032 20.5 0.3 3.2 1 1 2 3 3 3 1 Centrosome localisation domain of PPC89 Snapin_Pallidin PF14712.1 EME86332.1 - 0.0046 17.2 6.2 0.022 15.0 0.2 2.3 2 1 0 2 2 2 1 Snapin/Pallidin Rootletin PF15035.1 EME86332.1 - 0.03 14.3 15.7 0.091 12.7 10.7 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.1 EME86332.1 - 0.03 12.8 5.4 0.036 12.5 3.8 1.2 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 EME86332.1 - 0.035 13.9 16.8 0.44 10.4 11.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EME86332.1 - 0.046 12.1 5.0 0.058 11.8 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GAS PF13851.1 EME86332.1 - 0.052 12.7 13.0 0.098 11.8 8.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 EME86332.1 - 0.056 13.1 5.9 0.067 12.9 3.7 1.4 1 1 0 1 1 1 0 Laminin Domain II MAD PF05557.8 EME86332.1 - 0.057 11.5 11.9 0.068 11.2 8.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Exonuc_VII_L PF02601.10 EME86332.1 - 0.057 12.5 6.3 0.071 12.2 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMCO5 PF14992.1 EME86332.1 - 0.059 12.4 7.9 0.074 12.1 5.5 1.2 1 0 0 1 1 1 0 TMCO5 family LPP PF04728.8 EME86332.1 - 0.067 12.9 0.2 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper GrpE PF01025.14 EME86332.1 - 0.069 12.6 0.4 0.069 12.6 0.3 2.4 2 1 0 2 2 2 0 GrpE Tektin PF03148.9 EME86332.1 - 0.08 11.4 14.3 0.038 12.5 1.7 2.1 1 1 1 2 2 2 0 Tektin family DUF3584 PF12128.3 EME86332.1 - 0.083 10.2 15.7 0.1 9.9 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TBPIP PF07106.8 EME86332.1 - 0.084 12.4 10.2 1.7 8.1 2.2 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C4H2 PF10146.4 EME86332.1 - 0.09 12.7 8.9 0.065 13.2 2.4 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein DUF1664 PF07889.7 EME86332.1 - 0.17 11.6 5.9 0.2 11.4 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.6 EME86332.1 - 0.2 9.1 1.7 0.25 8.8 1.1 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.7 EME86332.1 - 0.22 11.2 16.7 0.4 10.4 11.6 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 EME86332.1 - 0.25 10.7 8.1 0.36 10.2 5.6 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 Fib_alpha PF08702.5 EME86332.1 - 0.3 11.1 5.1 0.64 10.1 0.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EME86332.1 - 0.64 8.6 11.6 0.32 9.5 3.1 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Vfa1 PF08432.5 EME86332.1 - 0.79 9.7 7.7 1 9.3 5.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Atg14 PF10186.4 EME86332.1 - 1 8.2 14.2 1 8.2 9.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EME86332.1 - 1.1 7.0 9.3 1.7 6.4 6.1 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TACC PF05010.9 EME86332.1 - 1.2 8.8 13.1 0.59 9.8 2.8 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) 5_nucleotid PF05761.9 EME86332.1 - 1.5 7.2 4.0 1.7 7.0 2.8 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF2894 PF11445.3 EME86332.1 - 1.7 8.8 9.3 2.2 8.5 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Occludin_ELL PF07303.8 EME86332.1 - 1.9 9.2 7.1 2.6 8.8 1.9 2.4 1 1 2 3 3 3 0 Occludin homology domain FlaC_arch PF05377.6 EME86332.1 - 2.1 8.2 5.1 19 5.2 0.6 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 EME86332.1 - 2.2 8.3 13.3 18 5.3 9.4 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fmp27_WPPW PF10359.4 EME86332.1 - 2.3 6.5 8.7 4.8 5.4 6.0 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HAUS-augmin3 PF14932.1 EME86332.1 - 2.8 7.0 13.1 12 5.0 0.3 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CDC37_N PF03234.9 EME86332.1 - 3.3 7.9 9.8 1.9 8.7 2.5 2.0 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF724 PF05266.9 EME86332.1 - 3.4 7.2 13.8 0.24 11.0 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3708 PF12501.3 EME86332.1 - 3.5 7.4 7.9 1.8e+02 1.9 5.5 2.1 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter IncA PF04156.9 EME86332.1 - 3.9 7.0 18.2 9.7 5.7 12.5 1.7 1 1 0 1 1 1 0 IncA protein FUSC PF04632.7 EME86332.1 - 4.9 5.4 9.2 6.4 5.0 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_TATA_bd PF12325.3 EME86332.1 - 5 6.8 14.7 1.9 8.2 3.6 2.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.6 EME86332.1 - 6 6.7 11.7 5.2 6.9 1.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3540 PF12059.3 EME86332.1 - 6.4 6.3 11.0 3.9 7.0 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) ACCA PF03255.9 EME86332.1 - 6.6 6.2 7.2 3.5 7.1 1.2 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_DNA_bd PF12329.3 EME86332.1 - 7.1 6.5 18.3 1.4 8.7 7.5 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Kinesin-relat_1 PF12711.2 EME86332.1 - 8.3 6.8 11.2 1.5 9.2 0.9 3.0 1 1 2 3 3 3 0 Kinesin motor Jnk-SapK_ap_N PF09744.4 EME86332.1 - 9.6 6.1 13.3 1.9 8.4 4.7 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 adh_short PF00106.20 EME86333.1 - 5.5e-18 65.4 0.1 7.1e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86333.1 - 2.5e-11 43.8 0.0 3.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86333.1 - 0.046 13.3 0.2 0.063 12.9 0.2 1.4 1 1 0 1 1 1 0 KR domain Cupin_2 PF07883.6 EME86334.1 - 3.2e-16 58.5 0.5 2.7e-10 39.6 0.0 2.7 3 0 0 3 3 3 2 Cupin domain AraC_binding PF02311.14 EME86334.1 - 1.1e-07 31.6 0.1 0.00015 21.4 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 EME86334.1 - 4.4e-07 29.2 0.0 0.02 14.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.3 EME86334.1 - 0.00057 19.8 0.1 0.52 10.3 0.0 2.7 2 1 0 2 2 2 2 Mif2/CENP-C like Cupin_6 PF12852.2 EME86334.1 - 0.00075 19.1 0.2 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 Cupin FdtA PF05523.6 EME86334.1 - 0.0035 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 WxcM-like, C-terminal AraC_binding_2 PF14525.1 EME86334.1 - 0.13 11.8 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 AraC-binding-like domain Abhydrolase_3 PF07859.8 EME86335.1 - 9.3e-10 38.4 0.1 1.2e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME86335.1 - 1.7e-06 28.1 0.3 2.2e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EME86335.1 - 3.3e-06 26.1 0.1 7.5e-06 24.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EME86335.1 - 1.8e-05 24.5 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EME86335.1 - 0.21 10.1 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) ApbA_C PF08546.6 EME86336.1 - 2.2e-27 95.5 0.0 4.4e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME86336.1 - 2.9e-27 94.9 0.0 3.8e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EME86336.1 - 0.015 15.4 0.2 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EME86336.1 - 0.083 12.7 0.6 0.17 11.6 0.2 1.7 2 0 0 2 2 2 0 ThiF family RRM_1 PF00076.17 EME86337.1 - 2.7e-46 155.0 2.1 2.1e-20 72.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME86337.1 - 6.5e-34 115.7 0.3 2.8e-17 62.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EME86337.1 - 2.9e-25 88.3 0.2 7.6e-25 86.9 0.2 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EME86337.1 - 3.4e-25 87.6 0.4 7.3e-08 32.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME86337.1 - 9.3e-07 28.6 0.8 0.01 15.6 0.0 3.6 3 0 0 3 3 3 2 RNA binding motif Cyt-b5 PF00173.23 EME86338.1 - 1.9e-20 72.4 0.3 1e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EME86338.1 - 3.4e-08 33.8 21.4 3.4e-08 33.8 14.8 1.9 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EME86338.1 - 0.021 14.8 0.3 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region COX14 PF14880.1 EME86338.1 - 0.088 12.4 1.7 0.19 11.3 0.2 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly HEAT_2 PF13646.1 EME86340.1 - 2e-18 66.4 0.2 1.1e-07 31.9 0.0 7.4 4 2 5 9 9 9 7 HEAT repeats HEAT_EZ PF13513.1 EME86340.1 - 2.5e-18 66.0 9.6 2.8e-08 34.0 0.0 10.0 9 2 2 11 11 11 2 HEAT-like repeat HEAT PF02985.17 EME86340.1 - 1.7e-16 58.7 7.5 7.4e-06 25.6 0.0 9.9 12 0 0 12 12 12 2 HEAT repeat IBN_N PF03810.14 EME86340.1 - 2.8e-10 39.9 5.4 1.8e-09 37.3 0.0 4.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EME86340.1 - 4.6e-07 29.4 4.0 0.0049 16.2 0.1 5.1 4 2 2 6 6 6 2 CLASP N terminal Arm PF00514.18 EME86340.1 - 1.3e-05 24.8 2.9 3.5 7.6 0.0 5.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EME86340.1 - 3.4e-05 23.5 2.6 0.0066 16.1 0.0 4.5 2 1 2 5 5 5 2 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 EME86340.1 - 0.00026 21.1 0.3 4.6 7.9 0.0 5.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat TGT PF01702.13 EME86340.1 - 0.087 12.0 2.2 0.33 10.2 0.0 2.8 4 0 0 4 4 4 0 Queuine tRNA-ribosyltransferase RNR_inhib PF08591.5 EME86342.1 - 8.5e-09 36.2 3.4 1.1e-07 32.6 2.3 2.9 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Fucose_iso_C PF02952.12 EME86343.1 - 0.028 13.9 0.2 4.4 6.8 0.0 2.6 2 1 0 2 2 2 0 L-fucose isomerase, C-terminal domain DUF3723 PF12520.3 EME86344.1 - 7.8e-07 27.9 0.5 9.9e-07 27.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DEAD PF00270.24 EME86345.1 - 2e-44 151.0 0.0 4.7e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME86345.1 - 4.6e-26 90.4 0.1 1.6e-25 88.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EME86345.1 - 9.8e-07 27.5 3.0 6e-06 24.9 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) MAP65_ASE1 PF03999.7 EME86346.1 - 6.6e-77 259.5 8.8 6.6e-77 259.5 6.1 1.6 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Nup88 PF10168.4 EME86346.1 - 0.015 13.1 2.3 0.027 12.3 1.6 1.3 1 0 0 1 1 1 0 Nuclear pore component Spectrin PF00435.16 EME86346.1 - 0.026 14.7 9.6 0.75 10.1 0.4 3.5 2 1 0 2 2 2 0 Spectrin repeat PilX_N PF14341.1 EME86346.1 - 0.22 11.2 1.9 0.47 10.1 1.3 1.6 1 0 0 1 1 1 0 PilX N-terminal RPW8 PF05659.6 EME86346.1 - 0.24 10.9 4.0 0.46 10.0 0.0 3.1 3 1 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Abhydrolase_6 PF12697.2 EME86347.1 - 6.3e-07 29.4 0.0 1.3e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME86347.1 - 0.00044 19.8 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EME86347.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EME86347.1 - 0.029 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AA_permease_2 PF13520.1 EME86349.1 - 4.6e-58 196.7 51.2 6.3e-58 196.3 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86349.1 - 3.8e-18 65.0 43.6 5.4e-18 64.5 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease IncA PF04156.9 EME86349.1 - 0.029 13.9 0.5 0.029 13.9 0.3 3.2 6 0 0 6 6 6 0 IncA protein DUF3318 PF11780.3 EME86349.1 - 0.072 12.6 1.1 0.22 11.1 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Gram_pos_anchor PF00746.16 EME86349.1 - 6.1 6.7 0.0 6.1 6.7 0.0 4.0 4 1 1 5 5 5 0 Gram positive anchor WD40 PF00400.27 EME86350.1 - 4.1e-23 80.3 17.0 6.3e-07 29.0 0.1 6.4 7 1 0 7 7 7 5 WD domain, G-beta repeat Oest_recep PF02159.10 EME86350.1 - 0.031 14.4 1.1 0.12 12.4 0.1 2.4 3 0 0 3 3 3 0 Oestrogen receptor S1 PF00575.18 EME86351.1 - 1.2e-79 262.4 17.7 1e-15 57.5 0.2 13.3 13 1 0 13 13 13 10 S1 RNA binding domain EXOSC1 PF10447.4 EME86351.1 - 7.8e-07 28.9 6.6 0.41 10.6 0.0 7.1 8 0 0 8 8 8 2 Exosome component EXOSC1/CSL4 TPR_14 PF13428.1 EME86351.1 - 4.2e-06 26.9 1.4 0.037 14.6 0.0 5.2 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME86351.1 - 1.7e-05 25.3 1.6 7.4e-05 23.3 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.9 EME86351.1 - 7.3e-05 22.6 17.9 0.046 13.4 0.4 4.5 3 1 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EME86351.1 - 0.0025 17.3 0.6 0.0058 16.2 0.1 1.8 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EME86351.1 - 0.0026 17.6 2.7 0.091 12.7 0.8 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME86351.1 - 0.0043 17.3 6.5 0.32 11.3 0.0 4.1 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME86351.1 - 0.018 14.7 0.4 0.092 12.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME86351.1 - 0.18 11.7 0.6 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EME86351.1 - 0.26 11.5 1.0 9.8 6.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP59_mtransfer PF11735.3 EME86352.1 - 3.1e-84 281.9 0.0 4.8e-84 281.3 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 KR PF08659.5 EME86352.1 - 1.9e-39 135.1 0.0 1.6e-24 86.5 0.0 2.7 1 1 1 2 2 2 2 KR domain adh_short PF00106.20 EME86352.1 - 1.7e-29 102.8 0.0 3.3e-15 56.3 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase Methyltransf_12 PF08242.7 EME86352.1 - 2.8e-19 69.4 0.0 6.4e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME86352.1 - 4.6e-11 43.0 0.0 1.4e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME86352.1 - 1.7e-10 40.8 0.0 3.6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EME86352.1 - 1e-09 39.3 0.0 6.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EME86352.1 - 2.2e-09 37.0 0.0 4.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME86352.1 - 7.7e-08 32.8 0.0 2.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME86352.1 - 2.4e-06 27.8 0.0 8.9e-06 25.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EME86352.1 - 2.8e-06 27.4 0.0 9.9e-06 25.7 0.0 2.0 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EME86352.1 - 1.5e-05 24.7 0.0 3.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_26 PF13659.1 EME86352.1 - 0.00085 19.3 0.0 0.003 17.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME86352.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EME86352.1 - 0.017 15.9 0.0 0.05 14.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EME86352.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EME86352.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_28 PF02636.12 EME86352.1 - 0.14 11.5 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA PF00004.24 EME86355.1 - 3e-12 46.8 2.1 3.6e-11 43.3 1.5 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME86355.1 - 4.6e-07 30.0 0.1 2.3e-05 24.4 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 EME86355.1 - 3.4e-05 22.7 0.4 0.00055 18.7 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EME86355.1 - 0.00032 21.0 0.2 0.0071 16.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME86355.1 - 0.00041 20.4 0.4 0.0049 17.0 0.1 2.8 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EME86355.1 - 0.00062 18.6 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EME86355.1 - 0.0013 19.5 0.0 0.005 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EME86355.1 - 0.004 16.8 0.0 0.57 9.8 0.0 2.5 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.7 EME86355.1 - 0.011 14.7 0.0 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EME86355.1 - 0.032 13.9 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EME86355.1 - 0.032 13.9 0.7 0.53 10.0 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EME86355.1 - 0.043 13.7 0.3 0.68 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EME86355.1 - 0.045 13.4 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EME86355.1 - 0.07 13.0 0.1 0.88 9.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EME86355.1 - 0.096 11.5 0.4 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EME86355.1 - 0.15 12.2 0.3 0.79 9.9 0.0 2.4 3 0 0 3 3 2 0 RNA helicase Herpes_UL36 PF03586.8 EME86356.1 - 0.0036 16.4 0.3 0.0079 15.3 0.2 1.5 1 0 0 1 1 1 1 Herpesvirus UL36 tegument protein SurA_N_3 PF13624.1 EME86356.1 - 0.13 12.2 1.4 10 6.1 0.0 2.5 3 0 0 3 3 3 0 SurA N-terminal domain GDPD PF03009.12 EME86357.1 - 8.6e-16 58.2 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PTPLA PF04387.9 EME86358.1 - 4.6e-53 179.0 10.4 8.4e-53 178.1 7.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Prp19 PF08606.6 EME86360.1 - 2.2e-32 110.6 1.7 3.9e-30 103.3 1.6 2.4 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 EME86360.1 - 1.2e-18 66.2 2.3 3.3e-06 26.7 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EME86360.1 - 8e-06 25.6 0.1 0.015 15.0 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.3 EME86360.1 - 0.0083 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EME86360.1 - 0.0096 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 U-box domain Cytochrom_D1 PF02239.11 EME86360.1 - 0.012 13.9 0.0 0.07 11.4 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EME86360.1 - 0.021 13.0 0.0 0.035 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Lactonase PF10282.4 EME86360.1 - 0.025 13.6 0.3 0.64 9.0 0.0 2.9 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller F_bP_aldolase PF01116.15 EME86361.1 - 8.3e-101 336.8 0.0 9.4e-101 336.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RRM_1 PF00076.17 EME86362.1 - 8.2e-14 50.9 0.0 1.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME86362.1 - 3.3e-08 33.4 0.1 7.8e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4604 PF15377.1 EME86362.1 - 1.9 8.6 43.5 0.16 12.2 14.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) MFS_1 PF07690.11 EME86364.1 - 2.7e-24 85.5 38.1 7.8e-23 80.7 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86364.1 - 2.8e-15 55.8 2.7 2.8e-15 55.8 1.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.14 EME86364.1 - 0.00016 20.3 1.1 0.00016 20.3 0.8 1.6 2 0 0 2 2 2 1 LacY proton/sugar symporter PGAP1 PF07819.8 EME86366.1 - 1.7e-83 279.6 0.0 2.8e-83 278.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EME86366.1 - 2.4e-05 24.1 0.0 5.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME86366.1 - 0.00069 19.5 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EME86366.1 - 0.027 13.7 0.1 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EME86366.1 - 0.046 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 EME86366.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DIOX_N PF14226.1 EME86367.1 - 3.2e-27 95.3 0.0 5.5e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME86367.1 - 5.2e-23 81.2 0.0 2.8e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ald_Xan_dh_C2 PF02738.13 EME86368.1 - 1.1e-178 594.9 0.1 1.6e-178 594.5 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EME86368.1 - 7.2e-36 123.1 0.1 1.6e-35 122.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EME86368.1 - 1.8e-29 101.6 0.0 3.3e-28 97.6 0.0 2.9 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EME86368.1 - 2.7e-28 98.2 0.2 5.5e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EME86368.1 - 1.8e-24 85.4 0.1 3.9e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EME86368.1 - 7.6e-08 31.9 1.5 1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_30 PF02055.11 EME86370.1 - 3.2e-39 134.4 7.9 9.3e-39 132.9 5.5 1.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EME86370.1 - 0.0052 15.7 0.1 0.011 14.7 0.1 1.5 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF70 PF01901.11 EME86371.1 - 0.078 12.0 0.5 0.075 12.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF70 FYVE PF01363.16 EME86373.1 - 8.6e-22 76.8 24.2 3.3e-16 58.9 3.8 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 EME86373.1 - 0.00014 21.6 3.5 0.00014 21.6 2.4 3.8 4 1 0 4 4 4 1 AN1-like Zinc finger Rbsn PF11464.3 EME86373.1 - 0.00043 19.7 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Seryl_tRNA_N PF02403.17 EME86373.1 - 0.0084 16.1 1.3 0.028 14.4 0.9 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF2051 PF09738.4 EME86373.1 - 0.019 14.2 1.3 0.023 14.0 0.1 1.6 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) zf-Di19 PF05605.7 EME86373.1 - 0.026 14.6 0.1 0.026 14.6 0.0 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF393 PF04134.7 EME86373.1 - 0.37 11.9 3.1 5.7 8.0 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function, DUF393 FlxA PF14282.1 EME86373.1 - 3.2 7.7 8.8 0.18 11.7 1.0 2.2 2 0 0 2 2 2 0 FlxA-like protein Shugoshin_C PF07557.6 EME86375.1 - 0.052 13.0 0.6 0.052 13.0 0.4 2.6 3 0 0 3 3 3 0 Shugoshin C terminus AA_permease_2 PF13520.1 EME86377.1 - 1.1e-69 235.0 43.2 1.4e-69 234.7 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86377.1 - 1.6e-14 53.1 39.2 2.2e-14 52.6 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.11 EME86378.1 - 1.3e-32 113.5 0.1 1.7e-32 113.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EME86378.1 - 0.036 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 CsiD GMC_oxred_N PF00732.14 EME86379.1 - 3.4e-09 36.2 0.0 8.8e-09 34.9 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME86379.1 - 7.7e-09 35.9 0.0 2.6e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EME86379.1 - 0.0014 17.5 1.5 0.0023 16.8 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME86379.1 - 0.0044 16.9 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UBA_2 PF08587.6 EME86379.1 - 0.052 13.7 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) FAD_oxidored PF12831.2 EME86379.1 - 0.058 12.4 0.6 0.091 11.8 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME86379.1 - 0.071 13.1 2.0 0.22 11.6 1.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME86379.1 - 0.079 11.8 1.0 1 8.1 1.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 EME86379.1 - 0.14 10.9 0.1 0.25 10.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EME86379.1 - 0.37 11.2 1.1 0.89 10.0 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acid_PPase PF12689.2 EME86380.1 - 0.035 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Solute_trans_a PF03619.11 EME86382.1 - 1.8e-100 335.8 6.5 2.2e-100 335.5 4.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha FAM220 PF15487.1 EME86382.1 - 0.13 11.5 2.8 0.22 10.8 1.9 1.3 1 0 0 1 1 1 0 FAM220 family MMS1_N PF10433.4 EME86384.1 - 2.4e-81 273.3 0.0 4.9e-81 272.3 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.13 EME86385.1 - 7.8e-24 84.3 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PI3_PI4_kinase PF00454.22 EME86386.1 - 3.8e-36 124.7 0.0 5.6e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 EME86387.1 - 1e-14 53.5 1.8 1.9e-14 52.7 1.2 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF2353 PF09789.4 EME86387.1 - 0.0028 16.9 2.5 0.0042 16.3 1.8 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Tropomyosin PF00261.15 EME86387.1 - 0.0035 16.4 5.0 0.005 15.9 3.5 1.1 1 0 0 1 1 1 1 Tropomyosin ATG16 PF08614.6 EME86387.1 - 0.011 15.5 5.0 0.019 14.7 3.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EME86387.1 - 0.061 13.1 4.3 0.04 13.7 1.3 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EME86387.1 - 0.077 12.1 1.2 0.11 11.6 0.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TF_Zn_Ribbon PF08271.7 EME86387.1 - 0.082 12.2 0.4 0.15 11.4 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding KLRAQ PF10205.4 EME86387.1 - 0.42 10.6 5.8 0.8 9.7 3.6 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 EME86387.1 - 0.93 9.0 5.8 1.5 8.3 4.0 1.2 1 0 0 1 1 1 0 IncA protein WD40_alt PF14077.1 EME86387.1 - 6.9 6.3 6.0 9.2 5.9 0.1 3.0 2 1 1 3 3 3 0 Alternative WD40 repeat motif Pga1 PF10333.4 EME86389.1 - 2.2e-05 24.2 0.1 4.7e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Cyclin_C PF02984.14 EME86389.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain Viral_Hsp90 PF03225.9 EME86389.1 - 0.17 10.1 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Tubulin PF00091.20 EME86390.1 - 6.3e-69 232.0 0.0 8.7e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME86390.1 - 1.9e-49 166.8 0.1 3.3e-49 166.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EME86390.1 - 0.0019 17.7 0.0 0.0043 16.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain WW PF00397.21 EME86391.1 - 2.6e-08 33.5 0.4 5e-08 32.6 0.3 1.5 1 0 0 1 1 1 1 WW domain Ras PF00071.17 EME86392.1 - 1.5e-65 219.4 0.6 1.8e-65 219.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME86392.1 - 1.1e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME86392.1 - 2.3e-16 59.5 0.3 3.1e-16 59.1 0.2 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME86392.1 - 1.3e-05 24.6 0.2 2.9e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME86392.1 - 1.6e-05 24.1 0.1 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME86392.1 - 5.9e-05 22.9 0.0 0.00015 21.7 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EME86392.1 - 0.00043 19.5 0.0 0.00062 19.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EME86392.1 - 0.00055 20.1 0.0 0.078 13.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME86392.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.6 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EME86392.1 - 0.0022 17.3 0.1 0.015 14.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EME86392.1 - 0.0048 16.1 0.0 0.013 14.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME86392.1 - 0.018 15.0 0.1 0.088 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EME86392.1 - 0.018 14.9 0.2 0.057 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME86392.1 - 0.033 13.9 0.1 0.091 12.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EME86392.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EME86392.1 - 0.051 12.5 0.1 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 EME86392.1 - 0.066 13.5 0.1 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EME86392.1 - 0.093 12.2 0.1 0.99 8.8 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PHD PF00628.24 EME86393.1 - 1.4e-05 24.6 4.7 3.5e-05 23.3 3.2 1.8 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 EME86393.1 - 0.0023 17.8 0.8 0.0056 16.6 0.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EME86393.1 - 0.1 12.5 1.2 0.38 10.7 0.8 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME86393.1 - 0.13 12.4 5.0 0.046 13.8 1.3 1.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EME86393.1 - 0.34 10.9 2.6 0.75 9.8 1.8 1.5 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.1 EME86393.1 - 7.2 6.0 6.5 2 7.8 1.9 2.0 2 0 0 2 2 2 0 PHD-finger p450 PF00067.17 EME86395.1 - 1.2e-64 218.5 0.0 1.6e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EME86397.1 - 1e-21 77.3 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME86397.1 - 2.8e-09 37.5 0.0 5.6e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME86397.1 - 3.8e-08 33.0 0.0 0.0023 17.5 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EME86397.1 - 4.7e-08 33.3 0.0 4e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME86397.1 - 2.6e-06 27.8 0.0 7.5e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME86397.1 - 0.00025 21.3 0.0 0.001 19.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME86397.1 - 0.0029 16.9 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EME86397.1 - 0.0066 16.4 0.0 0.062 13.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME86397.1 - 0.009 15.1 0.0 0.019 14.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EME86397.1 - 0.021 13.8 0.0 0.061 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 EME86397.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EME86397.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase FmrO PF07091.6 EME86397.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Apc15p PF05841.6 EME86398.1 - 9.9e-17 61.8 3.0 9.9e-17 61.8 2.1 2.7 2 1 1 3 3 3 1 Apc15p protein Abhydrolase_6 PF12697.2 EME86399.1 - 0.00025 21.0 0.8 0.0013 18.6 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86399.1 - 0.00064 19.4 0.2 0.001 18.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EME86399.1 - 0.014 14.7 0.0 0.2 10.9 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 2) SspB PF04386.8 EME86400.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Stringent starvation protein B zf-HIT PF04438.11 EME86401.1 - 0.013 15.1 5.7 0.029 13.9 4.0 1.5 1 0 0 1 1 1 0 HIT zinc finger C1_2 PF03107.11 EME86401.1 - 1.7 8.7 11.2 0.33 11.1 5.4 1.6 2 1 0 2 2 2 0 C1 domain C1_4 PF07975.7 EME86401.1 - 2.1 8.4 8.1 80 3.3 5.6 2.2 1 1 0 1 1 1 0 TFIIH C1-like domain FYVE_2 PF02318.11 EME86401.1 - 5.5 6.9 8.3 12 5.8 5.8 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger HSP70 PF00012.15 EME86403.1 - 2.5e-164 547.5 0.1 2.5e-164 547.5 0.1 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EME86403.1 - 1.5e-13 50.0 0.0 1.1e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EME86403.1 - 3.7e-06 26.7 0.3 0.0072 16.1 0.0 3.9 2 2 0 2 2 2 2 Cell division protein FtsA Ish1 PF10281.4 EME86403.1 - 0.17 12.0 0.8 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Ketoacyl-synt_C PF02801.17 EME86403.1 - 0.18 11.6 2.3 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Fungal_trans PF04082.13 EME86404.1 - 2.3e-22 79.1 3.4 3.1e-22 78.6 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86404.1 - 3.9e-06 26.6 7.0 6.8e-06 25.8 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME86404.1 - 0.0059 15.2 0.1 0.011 14.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_18 PF12847.2 EME86405.1 - 0.0043 17.6 0.0 0.0097 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME86405.1 - 0.0046 16.6 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME86405.1 - 0.0069 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME86405.1 - 0.014 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EME86405.1 - 0.025 13.3 0.0 0.072 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PCMT PF01135.14 EME86405.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EME86405.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.1 EME86405.1 - 0.082 13.2 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 EME86407.1 - 1.3e-24 86.9 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86407.1 - 1.5e-16 60.9 0.0 1.9e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME86407.1 - 2.3e-06 27.2 0.1 4.3e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME86407.1 - 7.2e-06 25.0 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME86407.1 - 8.3e-06 25.9 0.1 3e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EME86407.1 - 2.2e-05 24.1 0.1 8.2e-05 22.3 0.0 2.1 2 1 0 2 2 2 1 KR domain DUF1237 PF06824.6 EME86408.1 - 1.2e-173 577.6 0.0 1.3e-173 577.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) SNF2_N PF00176.18 EME86411.1 - 1.2e-67 227.8 0.4 1.2e-67 227.8 0.3 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME86411.1 - 1.4e-15 56.8 0.0 1e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1003 PF06210.6 EME86411.1 - 0.42 10.5 2.6 1.1 9.2 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Pentapeptide_4 PF13599.1 EME86412.1 - 1.7e-10 40.5 1.0 2.8e-10 39.8 0.7 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EME86412.1 - 1.7e-08 34.1 1.6 1.4e-07 31.2 1.8 2.0 2 0 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EME86412.1 - 0.00024 20.2 0.0 0.0005 19.2 0.0 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Chorismate_bind PF00425.13 EME86413.1 - 2.6e-80 269.4 0.0 3.5e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EME86413.1 - 1.6e-26 92.9 0.0 3.6e-26 91.8 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EME86413.1 - 1.2e-16 60.9 0.0 2.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EME86413.1 - 8e-06 25.4 0.2 0.0033 16.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 Longin PF13774.1 EME86414.1 - 2.3e-24 84.7 0.3 4.1e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EME86414.1 - 1.5e-16 59.7 0.4 1.3e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF4404 PF14357.1 EME86414.1 - 0.012 16.0 0.8 0.39 11.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ASXH PF13919.1 EME86415.1 - 9e-18 64.3 3.5 1.2e-17 64.0 2.4 1.1 1 0 0 1 1 1 1 Asx homology domain DUF668 PF05003.7 EME86415.1 - 0.074 13.2 0.1 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Elong_Iki1 PF10483.4 EME86416.1 - 2.5e-78 263.3 0.0 3.2e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EME86417.1 - 5.8e-23 81.5 30.9 9e-23 80.9 21.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Glyco_hydro_61 PF03443.9 EME86418.1 - 6e-80 268.1 0.8 7e-80 267.9 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldo_ket_red PF00248.16 EME86419.1 - 2.1e-57 194.0 0.0 2.4e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Uteroglobin PF01099.12 EME86419.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Uteroglobin family NmrA PF05368.8 EME86420.1 - 6.2e-31 107.4 0.1 8.1e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME86420.1 - 2.2e-08 34.3 0.2 6.8e-08 32.7 0.1 2.0 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EME86420.1 - 9.7e-08 31.7 0.2 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME86420.1 - 1.1e-06 27.5 0.1 1.8e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EME86420.1 - 0.0065 15.4 0.1 0.0093 14.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EME86420.1 - 0.0093 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EME86420.1 - 0.017 15.4 0.1 0.069 13.4 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EME86420.1 - 0.025 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EME86420.1 - 0.033 13.0 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EME86420.1 - 0.075 13.0 0.1 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EME86420.1 - 0.079 12.8 0.1 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans PF04082.13 EME86421.1 - 2.8e-11 42.8 0.0 5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.26 EME86422.1 - 8.8e-08 32.1 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RF-1 PF00472.15 EME86423.1 - 1.5e-26 92.3 2.8 2e-26 92.0 1.9 1.1 1 0 0 1 1 1 1 RF-1 domain DUF2992 PF11208.3 EME86423.1 - 1.2 9.0 10.2 1.5 8.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) HGTP_anticodon2 PF12745.2 EME86423.1 - 8.4 5.4 9.8 0.93 8.5 0.6 2.0 1 1 0 2 2 2 0 Anticodon binding domain of tRNAs IBR PF01485.16 EME86425.1 - 5.3e-17 61.4 34.9 1.6e-12 47.1 1.0 4.2 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 EME86425.1 - 1e-14 54.3 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EME86425.1 - 2.9e-05 23.7 7.1 2.9e-05 23.7 4.9 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EME86425.1 - 0.00062 19.3 8.9 0.00062 19.3 6.2 4.3 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME86425.1 - 0.0014 18.6 8.3 0.0014 18.6 5.8 3.8 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.16 EME86426.1 - 2.1e-13 50.0 1.5 2.8e-13 49.6 0.7 1.4 1 1 0 1 1 1 1 PAP2 superfamily vWA-TerF-like PF10138.4 EME86427.1 - 1.4e-08 34.7 0.1 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EME86427.1 - 0.0035 17.4 0.6 0.021 14.9 0.4 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Pro_racemase PF05544.6 EME86427.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Proline racemase MFS_1 PF07690.11 EME86428.1 - 2.7e-31 108.5 25.8 3.3e-31 108.2 17.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EME86428.1 - 0.0011 18.9 6.5 0.28 11.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Acetyltransf_7 PF13508.1 EME86429.1 - 3.2e-07 30.3 0.1 7.4e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME86429.1 - 1.4e-06 28.1 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME86429.1 - 1.7e-06 28.1 0.0 4.2e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME86429.1 - 0.0014 18.5 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME86429.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EME86429.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein PseudoU_synth_2 PF00849.17 EME86430.1 - 2e-29 102.5 0.0 3.1e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EME86430.1 - 0.00059 19.2 0.1 0.0013 18.1 0.1 1.5 1 0 0 1 1 1 1 S4 domain AA_permease_2 PF13520.1 EME86431.1 - 3.9e-47 160.7 46.5 5.2e-47 160.3 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86431.1 - 1.1e-20 73.4 40.0 1.6e-20 72.9 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_42 PF02449.10 EME86432.1 - 1.4e-111 373.2 5.3 1.9e-111 372.8 3.7 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 EME86432.1 - 1.4e-31 109.2 0.0 2.4e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Cellulase PF00150.13 EME86432.1 - 1.1e-06 28.1 0.8 0.0001 21.6 0.1 2.4 1 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.12 EME86432.1 - 8.9e-05 21.3 0.2 0.00017 20.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 DUF4434 PF14488.1 EME86432.1 - 0.013 15.2 0.2 0.061 13.0 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) TSC22 PF01166.13 EME86433.1 - 0.0092 15.9 1.0 0.18 11.8 0.1 3.0 1 1 1 2 2 2 1 TSC-22/dip/bun family CALCOCO1 PF07888.6 EME86433.1 - 0.0092 14.3 1.6 0.013 13.8 1.1 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like FlxA PF14282.1 EME86433.1 - 0.13 12.1 1.6 0.31 11.0 1.1 1.6 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.3 EME86433.1 - 0.19 11.5 2.6 1.4 8.7 0.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EME86433.1 - 2.7 7.5 6.6 3 7.3 3.5 1.8 1 1 0 1 1 1 0 IncA protein Ank_2 PF12796.2 EME86434.1 - 3.4e-72 238.8 16.2 1.7e-19 69.9 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EME86434.1 - 2e-63 207.1 18.1 8.9e-08 31.5 0.3 11.1 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.1 EME86434.1 - 3.1e-49 163.8 8.2 5.6e-07 29.6 0.2 9.3 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME86434.1 - 5.2e-43 144.6 5.5 5e-09 36.4 0.0 7.5 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME86434.1 - 5.2e-43 140.7 9.0 0.00099 19.1 0.1 10.7 11 0 0 11 11 11 10 Ankyrin repeat Peptidase_M16 PF00675.15 EME86434.1 - 0.004 16.9 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) FSH1 PF03959.8 EME86436.1 - 9.5e-53 178.7 0.0 1.1e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EME86436.1 - 0.00014 21.7 0.1 0.034 14.0 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME86436.1 - 0.00042 19.6 0.0 0.00076 18.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME86436.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Phage_int_SAM_4 PF13495.1 EME86436.1 - 0.049 13.9 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SecE PF00584.15 EME86437.1 - 6e-13 48.1 0.0 6.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Amidase PF01425.16 EME86439.1 - 1.2e-69 235.3 0.2 2.7e-66 224.2 0.0 2.2 2 0 0 2 2 2 2 Amidase DUF1485 PF07364.7 EME86440.1 - 5.5e-75 252.2 0.0 1.7e-74 250.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 EME86440.1 - 1.1e-38 132.6 0.0 1.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 MlrC C-terminus Pribosyltran_N PF13793.1 EME86442.1 - 7.2e-43 145.0 0.7 1.5e-41 140.7 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EME86442.1 - 2.1e-35 122.1 0.0 7.3e-30 104.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EME86442.1 - 1.8e-06 27.7 0.0 0.00015 21.4 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Acetyltransf_1 PF00583.19 EME86443.1 - 1.7e-10 40.8 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME86443.1 - 5.7e-06 26.4 0.1 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME86443.1 - 1.5e-05 24.9 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME86443.1 - 0.00028 21.0 0.0 0.00038 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME86443.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EME86443.1 - 0.053 13.3 0.0 0.26 11.1 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME86443.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UPF0121 PF03661.8 EME86444.1 - 1.7e-09 37.2 0.2 2.3e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) MFS_1 PF07690.11 EME86445.1 - 4.6e-24 84.8 56.3 2.2e-18 66.1 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily P5-ATPase PF12409.3 EME86445.1 - 0.12 12.2 2.8 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 P5-type ATPase cation transporter Beta-lactamase PF00144.19 EME86446.1 - 1.1e-14 54.2 0.4 1.6e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EME86446.1 - 0.0084 15.9 0.1 0.024 14.4 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.19 EME86447.1 - 1.2e-15 57.3 0.0 1.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Yae1_N PF09811.4 EME86448.1 - 4e-10 39.0 2.0 7.7e-10 38.1 1.4 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal adh_short_C2 PF13561.1 EME86449.1 - 6.4e-30 104.6 0.0 7.6e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME86449.1 - 1.2e-26 93.6 0.0 4e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME86449.1 - 5.3e-08 32.7 0.0 2.2e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EME86449.1 - 0.0034 16.8 0.1 0.0086 15.5 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME86449.1 - 0.004 16.0 0.1 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EME86449.1 - 0.0048 15.6 0.1 0.0071 15.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.7 EME86449.1 - 0.0062 17.0 0.0 0.023 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME86449.1 - 0.01 16.4 0.1 0.017 15.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EME86449.1 - 0.015 15.3 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EME86449.1 - 0.043 13.3 0.1 0.088 12.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain DUF4354 PF14263.1 EME86449.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) 3HCDH_N PF02737.13 EME86449.1 - 0.051 13.2 0.2 0.096 12.3 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EME86449.1 - 0.074 13.0 0.3 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_15 PF09445.5 EME86449.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AAA_13 PF13166.1 EME86450.1 - 0.049 12.1 7.2 0.062 11.7 5.0 1.3 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 EME86450.1 - 0.21 11.2 19.1 0.18 11.5 0.6 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Prefoldin_3 PF13758.1 EME86450.1 - 0.52 10.1 4.9 0.73 9.6 0.1 2.9 2 1 1 3 3 3 0 Prefoldin subunit COG2 PF06148.6 EME86450.1 - 0.52 10.1 8.7 4.9 7.0 0.6 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 EME86450.1 - 0.62 9.8 4.0 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GvpK PF05121.7 EME86450.1 - 0.66 9.8 11.0 0.16 11.8 0.8 3.4 1 1 2 3 3 3 0 Gas vesicle protein K FlaC_arch PF05377.6 EME86450.1 - 1.9 8.4 6.6 14 5.6 0.3 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 EME86450.1 - 3.1 7.5 15.5 4.3 7.0 1.4 3.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Syntaxin PF00804.20 EME86450.1 - 3.9 7.6 9.3 2.9 8.0 3.4 2.9 2 1 0 2 2 2 0 Syntaxin BLOC1_2 PF10046.4 EME86450.1 - 4.2 7.5 8.5 0.87 9.7 1.8 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRE1 PF08647.6 EME86450.1 - 4.5 7.3 12.8 0.12 12.3 0.7 3.2 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.7 EME86450.1 - 6.5 6.5 20.0 0.15 11.7 2.0 3.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin PF02996.12 EME86450.1 - 7.9 6.1 12.7 2.5 7.7 1.1 3.6 1 1 2 3 3 3 0 Prefoldin subunit DUF566 PF04484.7 EME86451.1 - 0.37 10.2 13.7 0.76 9.2 9.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) MFS_1 PF07690.11 EME86452.1 - 2.6e-20 72.4 27.0 2.6e-20 72.4 18.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EME86452.1 - 9.4e-06 23.9 1.0 0.012 13.7 0.1 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 EME86452.1 - 0.0033 15.9 5.1 0.0033 15.9 3.6 3.0 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like Trp_oprn_chp PF09534.5 EME86452.1 - 0.17 11.4 0.1 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Allantoicase PF03561.10 EME86454.1 - 0.011 15.1 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Allantoicase repeat Fungal_trans_2 PF11951.3 EME86456.1 - 1.9e-07 30.0 0.0 2.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain UME PF08064.8 EME86456.1 - 0.0021 17.9 0.1 0.005 16.7 0.1 1.6 1 1 0 1 1 1 1 UME (NUC010) domain SNARE PF05739.14 EME86456.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 SNARE domain Pkinase PF00069.20 EME86459.1 - 2.2e-18 66.3 0.0 3e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME86459.1 - 4.1e-07 29.3 0.0 1.1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1534 PF07551.6 EME86460.1 - 0.021 14.3 0.0 0.064 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) MFS_1 PF07690.11 EME86461.1 - 1.2e-41 142.6 20.9 1.2e-41 142.6 14.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86461.1 - 2.6e-05 22.9 20.8 0.00029 19.5 14.4 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_1 PF00583.19 EME86462.1 - 1.3e-13 50.7 0.0 3e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME86462.1 - 7e-08 32.1 0.0 3.8e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EME86462.1 - 1.7e-07 31.3 0.0 3.2e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME86462.1 - 1e-05 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME86462.1 - 0.0065 16.6 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EME86462.1 - 0.012 14.8 0.1 0.026 13.7 0.0 1.5 1 1 1 2 2 2 0 MOZ/SAS family DUF3749 PF12568.3 EME86462.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_1 PF13232.1 EME86463.1 - 3.6e-05 23.9 1.1 3.6e-05 23.9 0.8 1.9 2 1 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME86463.1 - 0.00061 19.5 0.8 0.00061 19.5 0.5 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF2806 PF10987.3 EME86463.1 - 0.043 13.3 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) Ank_2 PF12796.2 EME86464.1 - 5.3e-14 52.3 1.8 1.3e-05 25.4 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME86464.1 - 2.9e-12 46.7 1.3 1.4e-05 25.4 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME86464.1 - 3.5e-09 36.0 1.3 0.012 15.7 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 EME86464.1 - 4.8e-09 35.5 1.1 0.0037 16.9 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EME86464.1 - 8.6e-09 35.3 0.9 0.0047 17.1 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EME86464.1 - 0.00018 21.0 0.1 0.0018 17.8 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Nup54 PF13874.1 EME86464.1 - 0.54 9.9 11.9 1.1 8.9 0.3 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin PF02996.12 EME86464.1 - 0.6 9.7 6.9 0.55 9.8 0.2 2.6 2 0 0 2 2 2 0 Prefoldin subunit CENP-Q PF13094.1 EME86464.1 - 0.75 9.8 20.8 4.6e+02 0.7 14.4 3.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 EME86464.1 - 7.3 6.9 11.4 15 6.0 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EME86465.1 - 0.00047 18.7 9.7 0.0007 18.1 6.7 1.2 1 0 0 1 1 1 1 AAA domain RNase_HII PF01351.13 EME86465.1 - 0.15 11.6 2.9 0.14 11.7 0.2 2.1 1 1 1 2 2 2 0 Ribonuclease HII DUF4407 PF14362.1 EME86465.1 - 1.3 7.9 10.7 1.5 7.6 2.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 EME86465.1 - 6.5 4.4 5.7 12 3.5 3.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HEAT_2 PF13646.1 EME86466.1 - 0.033 14.4 0.3 0.033 14.4 0.2 3.8 5 0 0 5 5 5 0 HEAT repeats zf-C4H2 PF10146.4 EME86466.1 - 0.038 14.0 2.8 0.051 13.5 0.2 2.4 3 0 0 3 3 3 0 Zinc finger-containing protein Dehydratase_MU PF02288.10 EME86466.1 - 0.11 12.2 0.0 0.44 10.3 0.0 2.1 1 0 0 1 1 1 0 Dehydratase medium subunit PIGA PF08288.7 EME86467.1 - 7.3e-42 141.6 0.7 1.8e-41 140.3 0.5 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EME86467.1 - 4e-25 88.1 0.0 6.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EME86467.1 - 2.2e-13 50.2 0.5 4e-13 49.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EME86467.1 - 2.5e-13 50.3 0.0 5.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EME86467.1 - 4.2e-10 39.9 0.0 7.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EME86467.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EME86467.1 - 0.0016 18.3 0.1 0.0036 17.1 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 EME86467.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DEAD PF00270.24 EME86468.1 - 1.5e-31 109.1 0.0 1.8e-15 56.8 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EME86468.1 - 9.4e-10 38.2 0.0 3e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME86468.1 - 7.6e-06 25.8 0.0 1.9e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.7 EME86468.1 - 0.0078 14.1 4.7 0.011 13.7 3.2 1.2 1 0 0 1 1 1 1 Nop14-like family AAA_22 PF13401.1 EME86468.1 - 0.054 13.6 0.2 4.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EME86468.1 - 0.071 11.8 0.0 0.15 10.8 0.0 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain HycA_repressor PF11046.3 EME86468.1 - 0.14 12.0 0.0 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Transcriptional repressor of hyc and hyp operons CDC45 PF02724.9 EME86468.1 - 0.41 8.6 6.4 0.71 7.8 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EME86468.1 - 1.2 8.1 7.2 1.9 7.4 5.0 1.3 1 0 0 1 1 1 0 BUD22 DUF536 PF04394.9 EME86468.1 - 1.6 8.4 5.5 0.15 11.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF536 AMP-binding PF00501.23 EME86469.1 - 3.1e-76 256.4 0.0 3.7e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME86469.1 - 1.7e-16 60.9 0.2 8.8e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain OB_NTP_bind PF07717.11 EME86470.1 - 2e-18 66.2 0.0 1.3e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EME86470.1 - 4.7e-13 48.7 0.1 1.7e-12 47.0 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EME86470.1 - 6.8e-09 35.6 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EME86470.1 - 7.7e-09 35.2 2.7 1.2e-08 34.5 0.4 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 EME86470.1 - 1e-05 25.4 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_29 PF13555.1 EME86470.1 - 0.003 17.0 0.4 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EME86470.1 - 0.0036 16.2 0.1 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EME86470.1 - 0.0049 17.0 2.6 0.0085 16.2 0.7 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EME86470.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EME86470.1 - 0.0074 15.4 0.1 0.02 14.0 0.1 1.7 1 0 0 1 1 1 1 KaiC UBA PF00627.26 EME86470.1 - 0.0088 15.8 0.3 0.25 11.2 0.0 3.3 3 0 0 3 3 3 1 UBA/TS-N domain PhoH PF02562.11 EME86470.1 - 0.027 13.6 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EME86470.1 - 0.036 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DND1_DSRM PF14709.1 EME86470.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_23 PF13476.1 EME86470.1 - 0.042 14.1 0.1 0.085 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME86470.1 - 0.65 10.3 2.5 2.3 8.5 0.7 2.4 1 1 1 2 2 2 0 ABC transporter DUF3143 PF11341.3 EME86471.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Peptidase_C97 PF05903.9 EME86473.1 - 1.8e-24 86.2 0.0 1.9e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EME86475.1 - 5.3e-32 110.6 0.0 7.8e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EME86475.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain GDA1_CD39 PF01150.12 EME86476.1 - 4.9e-96 321.8 0.0 6.4e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MKT1_C PF12246.3 EME86477.1 - 3.7e-43 147.2 0.0 5.5e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EME86477.1 - 1.9e-22 79.3 0.0 5.5e-22 77.8 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EME86477.1 - 1.2e-07 31.7 0.1 2.6e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EME86477.1 - 3.9e-06 27.0 0.0 0.00014 22.0 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain IGF2_C PF08365.6 EME86477.1 - 0.084 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide HET PF06985.6 EME86478.1 - 1.4e-23 83.6 7.8 4e-23 82.1 5.4 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) L51_S25_CI-B8 PF05047.11 EME86479.1 - 1.7e-12 46.8 0.4 3.2e-12 45.9 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MAPEG PF01124.13 EME86480.1 - 2.2e-20 72.5 1.8 2.8e-20 72.2 1.2 1.1 1 0 0 1 1 1 1 MAPEG family Glyco_hydro_2_N PF02837.13 EME86481.1 - 5.3e-28 97.6 0.1 1.2e-27 96.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EME86481.1 - 6.9e-12 45.7 0.0 5.9e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EME86481.1 - 3e-11 42.7 0.0 5.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain MR_MLE_C PF13378.1 EME86482.1 - 2.1e-21 75.9 0.4 4.1e-20 71.8 0.1 3.0 1 1 2 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EME86482.1 - 0.00015 22.1 0.0 0.00038 20.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain FAP PF07174.6 EME86485.1 - 0.019 14.3 17.2 0.034 13.4 11.9 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3975 PF13126.1 EME86486.1 - 0.015 15.3 0.5 0.026 14.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) zf-DHHC PF01529.15 EME86488.1 - 1.4e-38 132.0 0.1 1.4e-38 132.0 0.0 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-MYND PF01753.13 EME86490.1 - 3.3e-06 26.8 6.5 3.3e-06 26.8 4.5 3.2 5 0 0 5 5 5 1 MYND finger F-box PF00646.28 EME86490.1 - 0.00058 19.4 0.2 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME86490.1 - 0.05 13.3 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1115 PF06544.7 EME86490.1 - 0.08 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) Pyr_redox_2 PF07992.9 EME86491.1 - 7.4e-25 88.0 0.0 1.3e-24 87.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME86491.1 - 1.5e-09 38.1 0.1 2.6e-06 27.7 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME86491.1 - 6e-05 23.2 0.0 0.027 14.5 0.0 3.1 2 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME86491.1 - 0.00041 19.3 0.0 0.32 9.7 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EME86491.1 - 0.0018 17.2 0.0 1.6 7.5 0.0 3.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME86491.1 - 0.0088 15.8 0.0 0.16 11.6 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EME86491.1 - 0.018 13.9 0.0 0.18 10.6 0.0 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EME86491.1 - 0.024 14.8 0.8 0.52 10.6 0.0 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Sugar_tr PF00083.19 EME86493.1 - 3e-70 237.0 21.5 3.5e-70 236.8 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME86493.1 - 6e-27 94.2 26.4 6e-27 94.2 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CheX PF13690.1 EME86494.1 - 0.001 18.8 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX Packaging_FI PF14000.1 EME86494.1 - 0.034 14.3 1.9 0.059 13.5 1.3 1.3 1 0 0 1 1 1 0 DNA packaging protein FI Nop14 PF04147.7 EME86494.1 - 0.057 11.3 3.9 0.054 11.4 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family NUP50 PF08911.6 EME86494.1 - 0.67 10.3 0.1 0.67 10.3 0.1 3.1 3 0 0 3 3 3 0 NUP50 (Nucleoporin 50 kDa) YL1 PF05764.8 EME86494.1 - 0.82 9.2 9.7 1.6 8.3 6.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EME86494.1 - 1.2 7.0 6.6 1.5 6.7 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SnoaL_4 PF13577.1 EME86498.1 - 2.4e-23 82.4 0.0 3.4e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lactamase_B_2 PF12706.2 EME86499.1 - 1.4e-30 106.2 0.0 2.9e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EME86499.1 - 1.4e-21 75.7 0.1 2.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EME86499.1 - 6.7e-07 29.1 0.0 1.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily p450 PF00067.17 EME86500.1 - 1.6e-77 261.0 0.0 1.9e-77 260.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EME86501.1 - 2.3e-13 49.9 2.3 9.7e-12 44.5 1.6 2.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EME86501.1 - 8.8e-08 31.3 0.3 1.7e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME86501.1 - 2.9e-07 29.7 3.5 5e-05 22.3 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME86501.1 - 1.7e-06 28.0 1.2 1.7e-05 24.8 0.8 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME86501.1 - 4.2e-05 22.2 0.9 0.0006 18.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EME86501.1 - 6.2e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EME86501.1 - 7.9e-05 21.9 0.3 0.00019 20.6 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME86501.1 - 0.00019 21.3 0.1 0.00064 19.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME86501.1 - 0.00051 20.4 0.8 0.23 11.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME86501.1 - 0.00071 18.5 0.2 0.0011 17.9 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EME86501.1 - 0.04 13.4 0.1 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EME86501.1 - 0.062 11.9 0.4 1.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EME86501.1 - 0.065 12.3 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EME86501.1 - 0.088 11.7 1.1 4.8 5.9 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EME86501.1 - 0.094 12.0 0.3 0.21 10.9 0.2 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FadA PF09403.5 EME86501.1 - 0.18 11.8 0.4 0.31 11.0 0.3 1.3 1 0 0 1 1 1 0 Adhesion protein FadA MFS_1 PF07690.11 EME86502.1 - 6.7e-32 110.5 27.4 6.7e-32 110.5 19.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_S7 PF00177.16 EME86503.1 - 9.8e-40 135.5 1.8 1.2e-39 135.2 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Glyco_hydro_92 PF07971.7 EME86504.1 - 5.6e-147 490.4 3.1 7.1e-147 490.0 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Cullin PF00888.17 EME86505.1 - 8.9e-128 427.3 0.0 1.1e-127 427.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME86505.1 - 9e-26 89.5 1.1 2.3e-25 88.1 0.8 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Sec16_C PF12931.2 EME86505.1 - 0.0079 15.9 0.4 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sec23-binding domain of Sec16 Peripla_BP_4 PF13407.1 EME86505.1 - 0.034 13.4 0.1 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain Lactonase PF10282.4 EME86506.1 - 8.8e-79 265.0 0.0 1.1e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Glyco_hydro_31 PF01055.21 EME86507.1 - 2.1e-177 590.4 5.6 2.6e-177 590.0 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 CBM_20 PF00686.14 EME86507.1 - 1.2e-17 63.2 0.0 3.6e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain Gal_mutarotas_2 PF13802.1 EME86507.1 - 2.1e-05 24.2 1.9 9.4e-05 22.1 1.3 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like DNA_pol_B PF00136.16 EME86508.1 - 2.2e-95 320.1 0.0 3.2e-95 319.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EME86508.1 - 7.3e-23 80.9 0.0 4.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EME86508.1 - 1.9e-17 63.0 5.2 1.9e-17 63.0 3.6 2.8 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta OPT PF03169.10 EME86509.1 - 1.8e-92 310.7 41.6 2.1e-92 310.5 28.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3353 PF11833.3 EME86509.1 - 7 6.0 6.7 3.1 7.1 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF3353) Methyltransf_6 PF03737.10 EME86510.1 - 2.2e-24 86.0 0.0 2.9e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Polysacc_deac_1 PF01522.16 EME86511.1 - 9e-23 80.2 0.0 1.9e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EME86511.1 - 0.00066 19.1 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 EME86511.1 - 0.0071 14.4 0.0 0.01 13.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2194) AAT PF03417.11 EME86512.1 - 1.1e-35 123.0 0.0 1.4e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EME86512.1 - 0.0024 18.1 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase dsDNA_bind PF01984.15 EME86514.1 - 6.3e-31 106.5 3.7 8.6e-31 106.1 2.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain CD99L2 PF12301.3 EME86514.1 - 0.0013 18.4 2.6 0.72 9.5 0.1 2.1 2 0 0 2 2 2 2 CD99 antigen like protein 2 DUF834 PF05754.9 EME86514.1 - 3.4 7.5 7.4 11 5.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF834) SET PF00856.23 EME86515.1 - 3.1e-08 34.0 0.0 7e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 SET domain DUF2288 PF10052.4 EME86515.1 - 0.14 11.8 0.5 5.8 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2288) Sas10_Utp3 PF04000.10 EME86516.1 - 1.8e-19 69.7 0.3 1.8e-19 69.7 0.2 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4001 PF13165.1 EME86517.1 - 6.9 6.4 6.6 14 5.4 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4001) AA_permease PF00324.16 EME86518.1 - 1.5e-127 425.8 39.0 2e-127 425.4 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME86518.1 - 5.3e-40 137.2 43.1 7.5e-40 136.7 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease RBP_receptor PF14752.1 EME86518.1 - 2.1 6.5 9.8 1.5 7.0 1.7 2.2 2 0 0 2 2 2 0 Retinol binding protein receptor AAA PF00004.24 EME86519.1 - 1.1e-11 45.0 0.0 2.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME86519.1 - 4.5e-06 26.8 0.0 7.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EME86519.1 - 2.9e-05 23.8 0.0 7.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EME86519.1 - 3.7e-05 23.3 0.1 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EME86519.1 - 4.4e-05 22.6 0.0 8.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EME86519.1 - 0.00012 20.9 0.0 0.00021 20.1 0.0 1.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EME86519.1 - 0.00083 19.2 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME86519.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME86519.1 - 0.0015 19.3 0.0 0.009 16.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME86519.1 - 0.0094 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EME86519.1 - 0.017 14.8 1.4 0.053 13.2 0.1 2.4 2 1 1 3 3 3 0 NTPase DUF258 PF03193.11 EME86519.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 EME86519.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EME86519.1 - 0.022 14.7 0.0 0.1 12.5 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain UPF0180 PF03698.8 EME86519.1 - 0.03 14.1 0.2 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) IstB_IS21 PF01695.12 EME86519.1 - 0.032 13.6 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EME86519.1 - 0.038 13.0 0.0 0.088 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EME86519.1 - 0.084 12.5 0.0 1.5 8.4 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EME86519.1 - 0.11 11.9 0.6 0.83 9.0 0.1 2.5 2 1 1 3 3 3 0 AAA domain vMSA PF00695.14 EME86519.1 - 0.21 10.7 1.3 0.83 8.7 0.0 2.0 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Ribosomal_L28e PF01778.12 EME86520.1 - 3e-29 101.7 0.9 3e-29 101.7 0.6 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EME86520.1 - 6.5e-19 67.8 2.1 1.4e-18 66.7 1.4 1.6 1 0 0 1 1 1 1 Mak16 protein C-terminal region SCO1-SenC PF02630.9 EME86523.1 - 3.3e-62 209.1 0.0 4.4e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EME86523.1 - 2.3e-06 27.3 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EME86523.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EME86523.1 - 0.0098 15.4 0.0 0.067 12.7 0.0 2.0 1 1 0 1 1 1 1 Redoxin ATP-grasp_4 PF13535.1 EME86525.1 - 7e-11 42.1 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EME86525.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Fungal_trans PF04082.13 EME86527.1 - 2.4e-06 26.6 0.6 3.8e-06 25.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Leu_leader PF08054.6 EME86527.1 - 0.089 12.4 0.9 4.7 6.9 0.1 3.0 2 0 0 2 2 2 0 Leucine operon leader peptide NmrA PF05368.8 EME86528.1 - 2.9e-34 118.3 0.0 3.8e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME86528.1 - 1.5e-14 54.4 0.0 2.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EME86528.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME86528.1 - 9.9e-06 25.1 0.0 2.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EME86528.1 - 9.1e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EME86528.1 - 0.00013 20.9 0.0 0.24 10.3 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EME86528.1 - 0.0067 15.1 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EME86528.1 - 0.019 14.8 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Interferon PF00143.14 EME86528.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain Semialdhyde_dh PF01118.19 EME86528.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mur_ligase PF01225.20 EME86528.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Mur ligase family, catalytic domain NPP1 PF05630.6 EME86529.1 - 7.2e-19 68.3 0.0 1.2e-13 51.2 0.0 2.6 2 1 1 3 3 3 2 Necrosis inducing protein (NPP1) DUF677 PF05055.7 EME86532.1 - 0.0085 14.7 0.5 0.016 13.8 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF677) ADIP PF11559.3 EME86532.1 - 0.36 10.7 15.0 3 7.7 4.7 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding PEP-utilisers_N PF05524.8 EME86532.1 - 0.48 10.2 8.2 2.4 7.9 1.1 2.7 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal DUF2407_C PF13373.1 EME86532.1 - 0.78 9.6 3.0 3.3 7.6 0.6 2.5 2 0 0 2 2 2 0 DUF2407 C-terminal domain Cohesin_load PF10345.4 EME86533.1 - 2.4e-109 366.2 0.1 2.9e-109 366.0 0.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor GYD PF08734.6 EME86534.1 - 0.052 13.2 0.5 0.097 12.4 0.3 1.4 1 0 0 1 1 1 0 GYD domain Thioredoxin_4 PF13462.1 EME86534.1 - 0.47 10.4 3.7 0.67 9.9 2.5 1.2 1 0 0 1 1 1 0 Thioredoxin Abhydrolase_6 PF12697.2 EME86535.1 - 1.4e-11 44.7 0.0 2.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME86535.1 - 1.6e-08 34.3 0.0 4.9e-08 32.8 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME86535.1 - 1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EME86535.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) UPF0220 PF05255.6 EME86536.1 - 5.3e-62 207.9 2.8 5.8e-62 207.8 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) AAA_13 PF13166.1 EME86537.1 - 0.00091 17.8 17.1 0.0012 17.4 11.8 1.1 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 EME86537.1 - 0.0022 15.4 12.9 0.0022 15.4 9.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) FlxA PF14282.1 EME86537.1 - 0.013 15.3 16.7 0.036 14.0 1.7 2.5 2 0 0 2 2 2 0 FlxA-like protein TMF_DNA_bd PF12329.3 EME86537.1 - 0.023 14.4 1.9 0.023 14.4 1.3 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 EME86537.1 - 0.059 13.6 1.5 0.059 13.6 1.1 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF904) CENP-Q PF13094.1 EME86537.1 - 0.092 12.7 11.4 0.26 11.2 1.6 2.6 3 0 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit OEP PF02321.13 EME86537.1 - 0.15 11.6 19.5 1.1 8.8 2.3 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein ADIP PF11559.3 EME86537.1 - 0.3 11.0 25.2 1.5 8.6 2.4 2.4 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EME86537.1 - 0.66 9.5 20.3 3.2 7.3 7.3 2.1 1 1 1 2 2 2 0 IncA protein Val_tRNA-synt_C PF10458.4 EME86537.1 - 0.74 9.9 16.3 0.12 12.4 0.5 3.5 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Ribosomal_L3 PF00297.17 EME86537.1 - 0.75 9.1 7.6 0.37 10.1 3.5 1.7 1 1 1 2 2 2 0 Ribosomal protein L3 Phage_lysis PF03245.8 EME86537.1 - 1.1 9.2 20.0 0.082 12.8 1.0 2.7 1 1 0 2 2 2 0 Bacteriophage Rz lysis protein LMBR1 PF04791.11 EME86537.1 - 1.4 7.4 3.3 1.3 7.4 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4200 PF13863.1 EME86537.1 - 1.9 8.4 28.1 1 9.2 1.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) ERM PF00769.14 EME86537.1 - 3.2 7.2 24.5 4.9 6.6 0.1 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.1 EME86537.1 - 3.3 6.8 19.2 5.1 6.2 1.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Striatin PF08232.7 EME86537.1 - 3.4 7.9 20.1 4.5e+02 1.1 3.5 3.0 1 1 1 2 2 2 0 Striatin family Tropomyosin_1 PF12718.2 EME86537.1 - 3.4 7.4 27.1 0.41 10.4 2.2 2.6 1 1 0 2 2 2 0 Tropomyosin like DUF3450 PF11932.3 EME86537.1 - 3.9 6.6 23.5 1.2 8.3 1.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) End3 PF12761.2 EME86537.1 - 6.1 6.4 17.5 8.4 5.9 6.7 2.3 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.6 EME86537.1 - 8.4 6.1 13.3 1.4 8.5 0.5 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 EME86537.1 - 8.9 5.2 17.7 4.5 6.2 0.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 4HBT_2 PF13279.1 EME86538.1 - 4.3e-09 36.8 0.0 6.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily p450 PF00067.17 EME86539.1 - 6.7e-50 169.9 0.0 1.4e-49 168.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Spc97_Spc98 PF04130.8 EME86540.1 - 5.6e-132 440.8 3.4 7e-132 440.5 2.4 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EME86541.1 - 5.8e-53 179.0 0.1 7.3e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME86541.1 - 1.2e-13 50.0 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EME86541.1 - 0.13 11.9 0.1 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) ADH_N PF08240.7 EME86542.1 - 7.4e-25 86.8 0.8 1.3e-24 86.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME86542.1 - 7.8e-17 61.0 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME86542.1 - 0.033 15.0 0.0 0.053 14.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EME86542.1 - 0.04 13.9 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME86542.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Mak10 PF04112.8 EME86545.1 - 4e-42 143.2 0.0 1.1e-41 141.8 0.0 1.7 1 1 1 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EME86546.1 - 4.7e-24 83.6 2.3 7e-24 83.1 1.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PMBR PF09373.5 EME86546.1 - 0.089 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Pseudomurein-binding repeat Peptidase_M16 PF00675.15 EME86547.1 - 1.1e-17 64.2 0.0 1.9e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EME86547.1 - 2.4e-12 46.9 0.0 4.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EME86548.1 - 4.9e-35 121.3 2.3 1.6e-31 109.8 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EME86548.1 - 3.3e-15 55.6 3.8 6.4e-09 35.5 0.2 4.5 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EME86548.1 - 2.3e-11 43.1 0.4 0.00048 19.5 0.1 3.6 3 1 1 4 4 4 2 TFIIE alpha subunit TrmB PF01978.14 EME86548.1 - 0.00046 19.8 0.2 3 7.6 0.0 4.3 4 0 0 4 4 4 2 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 EME86548.1 - 0.92 9.3 7.8 5.3 6.9 0.5 4.2 4 0 0 4 4 4 0 Helix-turn-helix domain Herpes_UL42 PF02282.11 EME86549.1 - 0.061 12.9 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) DbpA PF03880.10 EME86550.1 - 0.084 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain Cullin PF00888.17 EME86552.1 - 1.1e-190 635.1 11.9 1.1e-190 635.1 8.2 1.3 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EME86552.1 - 1.4e-28 98.5 4.7 1.4e-28 98.5 3.2 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain PSD4 PF07631.6 EME86552.1 - 0.42 10.9 6.0 0.89 9.9 1.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) CHCH PF06747.8 EME86553.1 - 3e-07 30.1 3.0 5.5e-07 29.3 2.1 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EME86553.1 - 0.00063 19.8 1.5 0.0012 18.8 1.1 1.4 1 0 0 1 1 1 1 GCK domain TPK_catalytic PF04263.11 EME86554.1 - 1.5e-25 89.1 0.0 2.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EME86554.1 - 2.9e-14 52.5 0.0 4.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain HEAT_EZ PF13513.1 EME86555.1 - 2.1e-26 91.6 10.3 2e-09 37.6 0.0 10.4 7 2 4 11 11 11 5 HEAT-like repeat HEAT PF02985.17 EME86555.1 - 1.1e-24 84.2 10.0 0.00024 20.9 0.1 9.6 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.1 EME86555.1 - 1.3e-24 86.2 3.7 2.2e-07 31.0 0.0 7.2 5 2 4 9 9 9 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EME86555.1 - 6.2e-13 48.9 0.1 0.0004 20.7 0.0 7.0 7 2 1 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EME86555.1 - 1.2e-07 31.7 1.0 0.0089 15.8 0.0 5.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EME86555.1 - 3.2e-06 26.9 5.9 1.7e-05 24.6 0.1 4.1 3 2 1 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EME86555.1 - 2.5e-05 23.7 3.0 5.9 6.1 0.0 7.0 6 2 1 8 8 8 1 CLASP N terminal Arm PF00514.18 EME86555.1 - 0.00056 19.6 0.9 16 5.5 0.0 5.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EME86555.1 - 0.0032 17.7 1.1 17 6.2 0.0 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat MMS19_C PF12460.3 EME86555.1 - 0.0047 15.6 6.9 0.39 9.3 0.1 4.2 3 1 2 5 5 5 2 RNAPII transcription regulator C-terminal Urb2 PF10441.4 EME86555.1 - 0.021 14.3 0.4 0.059 12.9 0.0 1.9 2 0 0 2 2 2 0 Urb2/Npa2 family V-ATPase_H_N PF03224.9 EME86555.1 - 0.39 9.7 4.5 2.4 7.1 0.1 3.2 3 1 1 4 4 4 0 V-ATPase subunit H SPRY PF00622.23 EME86556.1 - 1.2e-19 70.5 0.1 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain NAD_binding_10 PF13460.1 EME86557.1 - 0.00018 21.6 0.1 0.00025 21.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EME86557.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME86557.1 - 0.13 13.1 0.0 0.25 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HSP70 PF00012.15 EME86558.1 - 1.8e-59 201.2 18.8 2.3e-57 194.2 1.3 3.3 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EME86558.1 - 0.014 14.0 0.1 0.035 12.6 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein FGGY_C PF02782.11 EME86558.1 - 0.27 10.8 3.1 0.76 9.3 0.0 3.3 5 1 0 5 5 5 0 FGGY family of carbohydrate kinases, C-terminal domain Laminin_II PF06009.7 EME86558.1 - 4.4 7.0 11.9 1.3 8.7 4.8 2.5 2 0 0 2 2 2 0 Laminin Domain II Herpes_capsid PF06112.6 EME86558.1 - 10 6.1 13.6 2.6 8.0 2.1 3.6 3 1 0 3 3 3 0 Gammaherpesvirus capsid protein adh_short PF00106.20 EME86559.1 - 4.7e-18 65.6 0.1 2.6e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86559.1 - 1.1e-08 35.1 0.1 6.9e-08 32.5 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86559.1 - 3.7e-05 23.4 0.0 0.00026 20.6 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EME86559.1 - 0.0051 16.2 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME86559.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME86559.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Peptidase_C27 PF05407.7 EME86562.1 - 0.0048 16.6 0.6 0.0054 16.4 0.4 1.2 1 0 0 1 1 1 1 Rubella virus endopeptidase Methyltransf_23 PF13489.1 EME86563.1 - 7.4e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME86563.1 - 1.5e-10 40.8 0.0 1.4e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME86563.1 - 2e-08 34.8 0.1 3.7e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME86563.1 - 4.5e-08 33.4 0.0 8.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME86563.1 - 7.2e-07 29.6 0.0 4.6e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME86563.1 - 1e-05 24.7 0.0 0.013 14.5 0.0 2.9 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family MTS PF05175.9 EME86563.1 - 0.00029 20.2 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 EME86563.1 - 0.00064 18.8 0.0 0.0017 17.5 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EME86563.1 - 0.00075 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EME86563.1 - 0.00078 18.5 0.0 0.003 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EME86563.1 - 0.0066 16.4 0.0 0.052 13.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EME86563.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.1 EME86563.1 - 0.021 15.1 0.0 0.051 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 EME86564.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like Acetyltransf_1 PF00583.19 EME86566.1 - 0.0025 17.8 0.1 0.011 15.6 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME86566.1 - 0.062 13.4 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MarB PF13999.1 EME86566.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 MarB protein FAD_binding_4 PF01565.18 EME86567.1 - 8.3e-15 54.4 0.0 1.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_3 PF07859.8 EME86568.1 - 1.3e-53 181.7 0.0 1.7e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME86568.1 - 1.4e-07 30.6 1.7 9.7e-07 27.8 1.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EME86568.1 - 2.4e-07 30.2 0.0 0.0054 15.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME86568.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME86568.1 - 2.3e-05 24.4 0.1 3.9e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME86568.1 - 0.0001 21.6 0.1 0.00075 18.8 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2424 PF10340.4 EME86568.1 - 0.041 12.5 1.7 0.18 10.3 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) AXE1 PF05448.7 EME86568.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0139 PF03669.8 EME86569.1 - 0.022 14.2 0.1 0.031 13.8 0.1 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) Med12 PF09497.5 EME86570.1 - 6.6e-27 93.2 0.2 1.3e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 zf-Di19 PF05605.7 EME86571.1 - 0.022 14.9 1.6 0.04 14.0 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_2 PF00152.15 EME86573.1 - 4.2e-74 249.3 0.0 6.8e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME86573.1 - 3.7e-05 23.4 0.0 6.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME86573.1 - 0.018 14.2 0.1 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Nitroreductase PF00881.19 EME86574.1 - 3.4e-24 85.5 0.0 4.2e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Aminotran_4 PF01063.14 EME86574.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class IV Nuc_deoxyrib_tr PF05014.10 EME86575.1 - 2.1e-13 50.1 0.0 3.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase 2-Hacid_dh_C PF02826.14 EME86576.1 - 9.9e-51 171.4 0.2 1.5e-50 170.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME86576.1 - 5.9e-10 38.7 0.0 7.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME86576.1 - 2.8e-05 24.0 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EME86576.1 - 0.024 14.2 0.0 0.14 11.7 0.0 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain INT_SG_DDX_CT_C PF15300.1 EME86580.1 - 0.063 12.7 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus CMS1 PF14617.1 EME86582.1 - 3.1e-82 275.4 6.0 3.8e-82 275.1 4.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EME86582.1 - 8.5e-05 22.1 0.0 9.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase G-patch PF01585.18 EME86583.1 - 4.7e-07 29.4 2.8 1.2e-06 28.2 1.9 1.7 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.8 EME86583.1 - 9.2e-05 21.7 0.9 9.2e-05 21.7 0.6 2.1 3 0 0 3 3 3 1 RED-like protein N-terminal region G-patch_2 PF12656.2 EME86583.1 - 0.004 16.9 0.9 0.02 14.7 0.6 2.3 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_1 PF00076.17 EME86583.1 - 0.0049 16.4 0.0 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_4 PF01565.18 EME86584.1 - 7.6e-20 70.8 0.1 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME86584.1 - 0.00017 21.4 0.1 0.00051 19.8 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like zf-CCCH PF00642.19 EME86585.1 - 1.2e-06 27.9 15.9 0.00081 19.0 2.0 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DASH_Spc19 PF08287.6 EME86586.1 - 2e-44 150.8 4.7 2.9e-44 150.3 3.3 1.2 1 0 0 1 1 1 1 Spc19 UPF0184 PF03670.8 EME86586.1 - 0.016 15.3 2.1 0.032 14.3 0.1 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Paramyx_P_V_C PF03210.8 EME86586.1 - 0.042 13.7 0.1 0.074 12.9 0.1 1.4 1 1 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal COG5 PF10392.4 EME86586.1 - 0.093 12.6 10.0 1.5 8.7 0.1 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Spc7 PF08317.6 EME86586.1 - 1.2 7.7 6.8 2.2 6.8 0.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ABC1 PF03109.11 EME86587.1 - 1.7e-20 73.2 0.0 3.6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EME86587.1 - 0.019 14.6 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family XhlA PF10779.4 EME86587.1 - 3.5 7.6 5.8 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA CagY_M PF07337.6 EME86588.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 DC-EC Repeat DeoC PF01791.4 EME86589.1 - 2.5e-37 128.4 0.0 3.5e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EME86589.1 - 0.0056 15.6 0.1 0.0081 15.1 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EME86589.1 - 0.032 13.4 0.1 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.20 EME86589.1 - 0.076 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF362 PF04015.7 EME86589.1 - 0.086 12.3 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF362) Ribosomal_S27e PF01667.12 EME86590.1 - 4.2e-29 99.8 6.7 5.4e-29 99.5 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EME86590.1 - 0.012 15.4 1.4 0.013 15.3 0.9 1.2 1 0 0 1 1 1 0 IBR domain zf-CSL PF05207.8 EME86590.1 - 0.046 13.2 0.7 0.085 12.3 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger Peptidase_C65 PF10275.4 EME86592.1 - 3.4e-63 213.2 0.0 4.4e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 EME86594.1 - 1.2e-20 73.7 0.4 4.8e-20 71.8 0.1 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EME86594.1 - 1.3e-09 37.9 0.1 3.7e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EME86594.1 - 0.00019 21.0 2.7 0.26 11.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME86594.1 - 0.00062 19.6 0.4 1 9.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME86594.1 - 0.00097 18.8 0.4 0.077 12.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME86594.1 - 0.02 14.8 3.6 1.1 9.1 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EME86594.1 - 0.024 14.5 0.1 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_1 PF00515.23 EME86594.1 - 0.052 13.1 3.0 0.15 11.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EME86594.1 - 0.063 12.9 1.0 0.29 10.8 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EME86594.1 - 0.42 11.3 1.7 22 6.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CWC25 PF12542.3 EME86595.1 - 4.8e-24 84.6 0.1 4.8e-24 84.6 0.1 3.9 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EME86595.1 - 8.7e-10 38.4 6.2 8.7e-10 38.4 4.3 4.6 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.17 EME86596.1 - 8.4e-54 181.3 0.0 1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME86596.1 - 3e-15 56.7 0.0 4.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME86596.1 - 6.8e-10 38.4 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME86596.1 - 0.00026 20.2 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EME86596.1 - 0.0013 17.9 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EME86596.1 - 0.011 14.3 0.0 0.029 13.0 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EME86596.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EME86596.1 - 0.031 13.9 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EME86596.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter adh_short_C2 PF13561.1 EME86598.1 - 8.6e-28 97.7 0.0 1.1e-27 97.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME86598.1 - 2.1e-23 83.0 0.0 3.9e-23 82.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME86598.1 - 1.2e-05 25.0 0.0 8.7e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 EME86598.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Annexin PF00191.15 EME86599.1 - 1e-24 86.1 4.7 8.8e-06 25.5 0.0 4.5 4 0 0 4 4 4 4 Annexin CorA PF01544.13 EME86600.1 - 4.4e-10 39.0 0.0 9.3e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SNARE_assoc PF09335.6 EME86600.1 - 0.028 14.6 0.2 0.065 13.4 0.1 1.6 1 0 0 1 1 1 0 SNARE associated Golgi protein MoaE PF02391.12 EME86602.1 - 2.8e-31 107.7 0.0 3.6e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 MoaE protein RRM_6 PF14259.1 EME86603.1 - 2.4e-07 30.6 0.0 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME86603.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.13 EME86604.1 - 1.7e-30 106.0 0.0 6.9e-10 38.4 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EME86604.1 - 0.0013 18.2 0.1 0.0082 15.6 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EME86604.1 - 0.0024 17.8 0.0 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PsiA PF06952.6 EME86604.1 - 0.0043 16.1 0.5 0.0081 15.2 0.4 1.4 1 0 0 1 1 1 1 PsiA protein Miro PF08477.8 EME86604.1 - 0.0055 17.1 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EME86604.1 - 0.024 14.4 0.1 0.11 12.2 0.1 2.0 1 1 1 2 2 2 0 Dynamin family Radical_SAM PF04055.16 EME86605.1 - 6.4e-15 55.7 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily PsbQ PF05757.6 EME86606.1 - 0.42 9.9 4.2 8.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Ras PF00071.17 EME86607.1 - 8.1e-55 184.6 0.0 9.5e-55 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME86607.1 - 5.1e-18 65.6 0.0 7.5e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME86607.1 - 2.7e-08 33.2 0.0 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME86607.1 - 0.00054 19.4 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2076 PF09849.4 EME86608.1 - 6.1e-09 36.3 8.1 6.9e-09 36.1 5.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EME86608.1 - 0.00036 20.3 1.3 0.00051 19.8 0.9 1.3 1 0 0 1 1 1 1 CHCH domain DUF605 PF04652.11 EME86608.1 - 1.4 8.2 10.2 1.7 7.9 7.0 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EME86608.1 - 6.8 4.7 9.6 7.9 4.5 6.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec2p PF06428.6 EME86609.1 - 5.9e-27 93.4 9.4 5.9e-27 93.4 6.5 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.3 EME86609.1 - 0.014 12.7 15.8 0.026 11.8 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HR1 PF02185.11 EME86609.1 - 0.039 13.6 22.8 5.3 6.8 11.4 3.3 2 1 0 2 2 2 0 Hr1 repeat DUF2408 PF10303.4 EME86609.1 - 0.047 13.8 7.9 0.092 12.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Prefoldin_2 PF01920.15 EME86609.1 - 0.099 12.4 22.5 0.022 14.4 5.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit Myosin_tail_1 PF01576.14 EME86609.1 - 0.41 8.3 25.2 1.2 6.7 17.4 1.7 1 1 0 1 1 1 0 Myosin tail Macoilin PF09726.4 EME86609.1 - 0.58 8.3 16.9 0.022 13.0 7.3 1.6 2 0 0 2 2 2 0 Transmembrane protein UPF0184 PF03670.8 EME86609.1 - 0.73 10.0 5.0 0.21 11.8 1.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Tup_N PF08581.5 EME86609.1 - 0.87 9.8 14.2 1.3 9.2 1.7 3.1 2 1 0 2 2 2 0 Tup N-terminal DUF4140 PF13600.1 EME86609.1 - 0.89 10.0 24.8 1.4 9.4 2.8 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1759 PF03564.10 EME86609.1 - 0.93 9.3 4.8 0.87 9.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4404 PF14357.1 EME86609.1 - 1.5 9.3 18.5 0.71 10.3 1.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) ADIP PF11559.3 EME86609.1 - 1.5 8.6 24.3 2.4 8.0 10.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.1 EME86609.1 - 2.7 7.9 23.8 5.6 6.9 1.8 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 EME86609.1 - 2.9 7.0 10.0 2.5 7.1 1.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EME86609.1 - 3.9 7.0 18.8 1.3 8.5 4.4 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 EME86609.1 - 4.1 7.1 24.4 2.2 8.0 1.3 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EME86609.1 - 5.4 6.8 12.1 8 6.2 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.9 EME86609.1 - 8.7 5.9 12.2 12 5.5 3.1 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Epimerase_Csub PF13950.1 EME86610.1 - 0.063 13.2 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit DUF3328 PF11807.3 EME86611.1 - 1.9e-21 76.7 0.0 3.6e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ATP-sulfurylase PF01747.12 EME86613.1 - 4.4e-88 294.1 0.1 6.1e-88 293.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EME86613.1 - 8e-56 188.0 0.1 1.2e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EME86613.1 - 5.6e-51 172.1 0.0 1e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EME86613.1 - 0.076 12.8 0.3 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain TP_methylase PF00590.15 EME86614.1 - 5.2e-48 163.5 0.1 1e-47 162.5 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EME86614.1 - 4.1e-12 46.2 0.0 8.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EME86614.1 - 1.4e-10 40.3 0.0 3.8e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EME86614.1 - 0.00059 18.7 0.1 0.0016 17.4 0.0 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rogdi_lz PF10259.4 EME86615.1 - 2.3e-74 249.9 0.0 2.6e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Snapin_Pallidin PF14712.1 EME86615.1 - 0.11 12.8 0.0 9.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin SUR7 PF06687.7 EME86616.1 - 3.2e-31 108.5 12.4 4e-31 108.2 8.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EME86616.1 - 2.1 7.9 23.2 0.52 9.9 13.5 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4646 PF15496.1 EME86618.1 - 2.2e-08 34.2 0.0 4.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) CoaE PF01121.15 EME86618.1 - 0.047 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase Mit_KHE1 PF10173.4 EME86618.1 - 0.068 13.0 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Thiol_cytolysin PF01289.14 EME86618.1 - 0.13 10.5 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin Peptidase_S10 PF00450.17 EME86619.1 - 1.6e-100 337.2 1.0 2e-100 336.9 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase B_lectin PF01453.19 EME86621.1 - 0.007 16.2 0.0 1.1 9.1 0.0 2.1 1 1 1 2 2 2 2 D-mannose binding lectin JmjC PF02373.17 EME86624.1 - 8.2e-40 135.6 0.8 1.7e-39 134.5 0.6 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EME86624.1 - 1.3e-15 56.5 0.7 3.4e-15 55.2 0.5 1.8 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.1 EME86624.1 - 1.6e-05 24.8 1.7 0.032 14.2 0.1 2.5 1 1 1 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME86624.1 - 0.00024 21.1 0.2 0.014 15.4 0.0 2.6 1 1 1 2 2 2 1 PHD-like zinc-binding domain Es2 PF09751.4 EME86625.1 - 4.4e-86 289.8 0.4 5.4e-86 289.5 0.3 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 FlxA PF14282.1 EME86626.1 - 0.021 14.7 1.0 0.021 14.7 0.7 3.1 2 1 0 2 2 2 0 FlxA-like protein DUF4288 PF14119.1 EME86626.1 - 0.023 14.7 0.0 0.089 12.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Endotoxin_N PF03945.9 EME86626.1 - 0.13 11.6 1.8 0.19 11.1 1.2 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain TMF_TATA_bd PF12325.3 EME86626.1 - 0.17 11.6 7.3 0.031 13.9 2.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Lipoprotein_20 PF13942.1 EME86626.1 - 8.1 5.9 13.5 9.9 5.6 0.2 2.9 1 1 2 3 3 3 0 YfhG lipoprotein WD40 PF00400.27 EME86628.1 - 1.9e-10 40.1 11.3 0.028 14.2 0.3 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Myb_DNA-bind_6 PF13921.1 EME86628.1 - 0.0011 18.9 0.0 0.0074 16.3 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain AA_permease_2 PF13520.1 EME86629.1 - 5.1e-56 190.0 56.3 6.1e-56 189.7 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86629.1 - 1.3e-30 106.2 49.8 1.7e-30 105.7 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M43 PF05572.8 EME86630.1 - 7.6e-15 54.8 0.4 1.3e-14 54.0 0.3 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EME86630.1 - 2.5e-07 30.8 1.4 3.5e-07 30.3 1.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EME86630.1 - 1.4e-05 24.6 4.1 2.6e-05 23.8 2.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EME86630.1 - 3.4e-05 24.3 0.3 6.4e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EME86630.1 - 0.00034 20.3 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 EME86630.1 - 0.00061 19.8 5.1 0.0012 18.9 3.5 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EME86630.1 - 0.072 11.9 5.0 0.64 8.8 3.4 2.1 1 1 0 1 1 1 0 Peptidase M66 CDC50 PF03381.10 EME86631.1 - 2e-97 325.7 0.0 2.7e-97 325.2 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sugar_tr PF00083.19 EME86632.1 - 8.6e-101 337.7 17.5 1e-100 337.4 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME86632.1 - 1.7e-30 105.9 17.8 1.7e-30 105.9 12.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EME86632.1 - 6.6e-05 22.6 0.1 0.00021 21.0 0.1 1.9 1 0 0 1 1 1 1 MFS_1 like family Mating_C PF12737.2 EME86632.1 - 5.2 5.8 10.7 7.8 5.2 7.4 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Tmemb_18A PF09771.4 EME86632.1 - 9.1 6.2 7.7 5 7.1 0.2 2.9 3 0 0 3 3 3 0 Transmembrane protein 188 PAN_2 PF08276.6 EME86633.1 - 0.036 13.8 0.4 0.068 13.0 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain Epimerase PF01370.16 EME86634.1 - 5.1e-26 91.5 0.0 7.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME86634.1 - 2.9e-09 36.2 0.0 5.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EME86634.1 - 3.5e-09 36.9 0.0 7.9e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME86634.1 - 4.5e-09 35.4 0.0 8.5e-09 34.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME86634.1 - 1.9e-08 33.5 0.0 1.9e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EME86634.1 - 6.2e-07 28.5 0.0 5.3e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EME86634.1 - 0.015 14.5 0.8 0.58 9.3 0.0 2.8 3 0 0 3 3 3 0 NmrA-like family adh_short PF00106.20 EME86634.1 - 0.11 12.4 0.1 0.78 9.6 0.1 2.5 1 1 0 1 1 1 0 short chain dehydrogenase AA_permease_2 PF13520.1 EME86636.1 - 2.2e-64 217.5 39.8 3.1e-64 217.0 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86636.1 - 1.9e-24 85.8 28.0 1.9e-24 85.8 19.4 2.1 1 1 1 2 2 2 1 Amino acid permease GTP_EFTU PF00009.22 EME86637.1 - 4.4e-62 208.8 0.2 6.1e-62 208.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EME86637.1 - 5.5e-38 129.2 0.0 1.6e-37 127.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EME86637.1 - 1.9e-21 75.7 0.0 5e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME86637.1 - 2.1e-12 46.9 1.2 9.3e-12 44.9 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EME86637.1 - 9.3e-12 44.6 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EME86637.1 - 1.1e-05 25.3 0.2 2.2e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME86637.1 - 0.023 14.5 0.2 0.14 11.9 0.1 2.2 1 1 0 1 1 1 0 Dynamin family RRM_6 PF14259.1 EME86639.1 - 1.4e-09 37.7 0.1 3.4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EME86639.1 - 3.3e-07 30.2 0.0 6.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EME86639.1 - 4e-06 26.3 0.2 7.7e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME86639.1 - 0.00013 21.7 0.1 0.00026 20.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EME86639.1 - 0.00049 19.7 3.5 0.0009 18.8 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 EME86639.1 - 0.0027 17.5 0.3 0.026 14.3 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1330) EAP30 PF04157.11 EME86639.1 - 0.55 9.3 4.0 0.91 8.6 2.8 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family AAA_23 PF13476.1 EME86639.1 - 2 8.6 5.6 3.2 8.0 3.9 1.3 1 0 0 1 1 1 0 AAA domain MBOAT_2 PF13813.1 EME86640.1 - 2.7e-16 59.3 6.0 2.7e-16 59.3 4.2 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Thia_YuaJ PF09515.5 EME86640.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) DUF4341 PF14241.1 EME86640.1 - 0.049 13.3 0.4 0.17 11.6 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) DUF308 PF03729.8 EME86640.1 - 6 6.9 12.1 7.9 6.5 1.1 3.4 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Tub_2 PF04525.7 EME86641.1 - 7.2e-07 28.7 0.0 3.1e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Tubby C 2 DUF726 PF05277.7 EME86642.1 - 1 8.1 4.4 1.2 7.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Esterase_phd PF10503.4 EME86643.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EME86643.1 - 0.045 13.4 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EME86643.1 - 0.15 11.3 0.1 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EME86643.1 - 0.23 10.6 1.0 1.1 8.4 0.3 2.4 1 1 1 2 2 2 0 Prolyl oligopeptidase family Fels1 PF05666.6 EME86644.1 - 0.015 14.6 0.1 0.05 12.9 0.1 1.9 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like HsbA PF12296.3 EME86645.1 - 2.7e-25 88.6 2.3 3.6e-25 88.2 1.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pyr_redox_2 PF07992.9 EME86647.1 - 8.8e-06 25.7 0.0 0.097 12.5 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME86647.1 - 0.00014 21.9 0.0 0.054 13.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME86647.1 - 0.0039 17.1 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME86647.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF1446 PF07287.6 EME86648.1 - 4.7e-103 344.4 3.1 9.9e-102 340.0 2.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Alpha-amylase PF00128.19 EME86649.1 - 8.4e-25 87.8 0.0 1e-23 84.2 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Toxin_35 PF10530.4 EME86649.1 - 0.032 14.3 0.1 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold Mito_carr PF00153.22 EME86650.1 - 4.1e-44 148.2 10.3 3.4e-16 58.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gtr1_RagA PF04670.7 EME86651.1 - 1.4e-59 201.1 0.0 1.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EME86651.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EME86651.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain PAP_central PF04928.12 EME86652.1 - 6.8e-93 310.1 0.1 1.4e-92 309.0 0.0 1.5 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EME86652.1 - 3.8e-37 127.2 0.0 5.8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EME86652.1 - 3.2e-07 30.5 0.0 7.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4257 PF14074.1 EME86653.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) HSP70 PF00012.15 EME86654.1 - 1.2e-11 43.2 0.7 5.6e-10 37.7 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EME86654.1 - 0.004 16.7 0.1 0.0092 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EME86654.1 - 0.019 13.5 0.0 0.079 11.5 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Mito_carr PF00153.22 EME86655.1 - 5.7e-53 176.6 2.0 4.9e-17 61.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_HII PF01351.13 EME86656.1 - 2.6e-49 167.5 0.0 3.3e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Tyrosinase PF00264.15 EME86657.1 - 1.5e-43 149.5 5.8 1.5e-43 149.5 4.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase BORG_CEP PF14957.1 EME86658.1 - 0.19 12.6 2.1 0.23 12.3 1.4 1.2 1 0 0 1 1 1 0 Cdc42 effector Mit_KHE1 PF10173.4 EME86660.1 - 7e-61 205.3 0.5 1.3e-60 204.5 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Chitin_synth_2 PF03142.10 EME86661.1 - 1.3e-251 835.5 1.5 1.7e-251 835.2 1.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EME86661.1 - 1.3e-169 565.5 0.0 1.8e-169 565.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EME86661.1 - 4e-23 81.0 0.0 4.3e-15 55.2 0.0 3.0 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EME86661.1 - 3.9e-15 56.0 4.6 1.3e-14 54.4 3.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EME86661.1 - 7.7e-15 55.3 0.3 5.6e-12 45.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EME86661.1 - 1.5e-14 53.4 0.6 5.7e-14 51.6 0.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EME86661.1 - 0.00015 21.4 0.0 0.011 15.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EME86661.1 - 0.0033 17.4 0.1 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME86661.1 - 0.0057 16.7 0.2 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Glyco_transf_21 PF13506.1 EME86661.1 - 0.015 14.6 0.4 0.074 12.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF258 PF03193.11 EME86661.1 - 0.033 13.3 0.1 0.096 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 adh_short PF00106.20 EME86662.1 - 9.1e-27 94.0 0.1 1.3e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86662.1 - 3e-24 86.1 0.0 9.1e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86662.1 - 1.3e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME86662.1 - 0.019 14.4 0.0 0.042 13.2 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EME86662.1 - 0.16 11.8 2.1 0.2 11.4 0.3 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Chitin_synth_2 PF03142.10 EME86663.1 - 1.4e-229 762.8 0.0 1.8e-229 762.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EME86663.1 - 1.8e-58 198.2 0.0 3.9e-58 197.0 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EME86663.1 - 3.4e-16 58.8 0.1 1.9e-11 43.5 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EME86663.1 - 2e-15 57.2 0.0 3e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME86663.1 - 1.1e-14 54.5 3.3 1.1e-14 54.5 2.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EME86663.1 - 2.7e-13 49.4 0.1 2.3e-12 46.4 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EME86663.1 - 4.9e-06 25.9 0.0 9.8e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME86663.1 - 0.03 14.0 0.0 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 SNARE PF05739.14 EME86664.1 - 7.8e-09 35.0 2.2 9.4e-09 34.8 1.5 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EME86664.1 - 0.0037 16.7 0.0 0.004 16.6 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF1241 PF06840.6 EME86664.1 - 0.09 12.0 0.1 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Pyr_redox_2 PF07992.9 EME86665.1 - 3.8e-22 79.1 0.1 2.9e-12 46.9 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME86665.1 - 1.5e-10 41.2 3.4 4.3e-07 30.2 0.5 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME86665.1 - 0.0005 20.1 0.6 0.71 9.9 0.0 3.2 3 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME86665.1 - 0.0093 15.9 0.1 0.16 12.0 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EME86665.1 - 0.014 14.4 0.5 1 8.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EME86665.1 - 0.047 12.5 1.7 2.8 6.6 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.9 EME86665.1 - 0.05 12.2 0.0 0.39 9.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EME86665.1 - 0.11 11.5 0.0 4.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 EME86665.1 - 0.12 11.3 0.0 2.9 6.7 0.0 2.5 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EME86665.1 - 0.15 12.3 0.0 2.7 8.2 0.0 2.5 1 1 1 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EME86665.1 - 0.2 10.5 4.5 6.2 5.6 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Aldo_ket_red PF00248.16 EME86666.1 - 3.5e-31 108.0 0.0 2.9e-25 88.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family NMO PF03060.10 EME86668.1 - 3.1e-19 69.3 0.0 3.6e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EME86668.1 - 0.0006 18.7 0.0 0.00073 18.5 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EME86669.1 - 1.3e-40 139.6 0.2 1.4e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EME86669.1 - 0.00027 19.9 0.9 0.00047 19.1 0.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EME86669.1 - 0.024 13.5 1.9 0.025 13.4 0.2 1.9 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 EME86669.1 - 0.092 11.6 0.3 0.17 10.8 0.1 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase BTB PF00651.26 EME86672.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain La PF05383.12 EME86673.1 - 3.8e-15 55.4 0.0 8.3e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EME86673.1 - 6.9e-11 41.9 0.1 4.4e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EME86673.1 - 3.1e-09 36.3 0.7 7.4e-09 35.1 0.5 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME86673.1 - 0.0017 18.1 0.1 0.0074 16.1 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.20 EME86674.1 - 5e-12 45.0 0.0 8.7e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EME86674.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain PLA2_B PF01735.13 EME86675.1 - 2.8e-26 91.7 0.0 4.3e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 EME86676.1 - 2.2e-75 253.7 0.1 5.6e-75 252.4 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit ParB PF08775.5 EME86676.1 - 0.035 14.4 1.4 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 ParB family MitMem_reg PF13012.1 EME86676.1 - 0.9 9.6 5.9 0.29 11.2 1.1 2.4 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function Septin PF00735.13 EME86677.1 - 5.9e-124 412.6 0.1 5.9e-124 412.6 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EME86677.1 - 9.2e-08 32.0 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME86677.1 - 1.6e-05 24.3 0.6 0.00063 19.2 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EME86677.1 - 3.6e-05 22.9 0.2 0.00026 20.2 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EME86677.1 - 0.00011 22.4 2.3 0.016 15.5 0.0 2.7 3 0 0 3 3 3 1 ABC transporter AIG1 PF04548.11 EME86677.1 - 0.00045 19.3 1.1 0.00096 18.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 EME86677.1 - 0.0011 18.4 2.1 0.0026 17.2 1.5 2.0 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 EME86677.1 - 0.0022 17.3 0.0 0.0079 15.6 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 EME86677.1 - 0.0023 17.9 0.1 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EME86677.1 - 0.0024 18.3 0.7 0.0078 16.7 0.0 2.2 3 0 0 3 3 1 1 Miro-like protein AAA_22 PF13401.1 EME86677.1 - 0.0034 17.5 0.1 0.018 15.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME86677.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EME86677.1 - 0.0072 15.8 0.7 0.015 14.7 0.0 1.9 2 0 0 2 2 1 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EME86677.1 - 0.017 14.7 0.4 2.1 7.8 0.0 2.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 EME86677.1 - 0.037 13.2 4.7 0.07 12.3 3.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_25 PF13481.1 EME86677.1 - 0.037 13.4 0.0 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EME86677.1 - 0.056 12.1 9.7 0.33 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EME86677.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EME86677.1 - 0.059 13.5 0.5 0.32 11.2 0.0 2.4 3 0 0 3 3 2 0 RNA helicase DUF1556 PF07590.6 EME86677.1 - 0.065 13.4 2.3 0.11 12.7 0.9 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1556) AAA_24 PF13479.1 EME86677.1 - 0.072 12.6 0.8 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EME86677.1 - 0.078 12.6 0.1 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EME86677.1 - 0.14 11.9 11.7 0.59 9.9 0.1 3.6 2 2 1 3 3 3 0 Dynamin family Phage_GPO PF05929.6 EME86677.1 - 0.15 11.2 5.5 0.24 10.6 3.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 EME86677.1 - 0.4 10.4 5.2 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 YlqD PF11068.3 EME86677.1 - 0.55 10.2 12.0 1 9.4 8.3 1.4 1 0 0 1 1 1 0 YlqD protein IncA PF04156.9 EME86677.1 - 1.5 8.3 9.3 2.5 7.6 6.5 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EME86677.1 - 9.2 5.2 12.7 14 4.6 8.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Lipase_GDSL_2 PF13472.1 EME86679.1 - 3.1e-17 63.2 0.0 4.5e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME86679.1 - 1.4e-15 57.8 0.0 1.9e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EME86679.1 - 0.00075 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Nodulin-like PF06813.8 EME86680.1 - 4.6e-14 52.2 3.0 1.9e-13 50.2 1.4 2.2 2 0 0 2 2 2 1 Nodulin-like Methyltransf_11 PF08241.7 EME86681.1 - 6.8e-13 48.9 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME86681.1 - 4.9e-10 39.2 0.0 5.9e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME86681.1 - 1.2e-09 38.1 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME86681.1 - 7.6e-08 32.6 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME86681.1 - 1.9e-07 31.4 0.0 4.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME86681.1 - 7e-05 23.3 0.0 0.00011 22.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EME86681.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1597 PF07642.6 EME86682.1 - 0.0041 16.2 0.5 0.005 15.9 0.3 1.1 1 0 0 1 1 1 1 Outer membrane protein family (DUF1597) Vps39_2 PF10367.4 EME86683.1 - 6e-09 36.0 0.0 1.7e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EME86683.1 - 0.00025 20.6 0.0 0.011 15.2 0.0 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.4 EME86683.1 - 0.0021 18.0 0.1 0.54 10.3 0.0 3.1 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 DUF605 PF04652.11 EME86683.1 - 1.9 7.8 7.4 2.8 7.2 5.1 1.2 1 0 0 1 1 1 0 Vta1 like CASP_C PF08172.7 EME86684.1 - 1.9e-86 289.1 0.1 1.9e-86 289.1 0.1 4.0 1 1 1 3 3 3 1 CASP C terminal DivIC PF04977.10 EME86684.1 - 0.021 14.3 0.6 0.021 14.3 0.4 7.7 6 2 3 9 9 9 0 Septum formation initiator Cast PF10174.4 EME86684.1 - 0.022 12.8 55.1 0.0077 14.3 35.0 1.9 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone DUF972 PF06156.8 EME86684.1 - 0.85 9.9 0.0 0.85 9.9 0.0 6.3 3 2 2 5 5 5 0 Protein of unknown function (DUF972) Hemerythrin PF01814.18 EME86684.1 - 1.2 9.3 9.3 4.4 7.4 0.3 4.0 4 1 0 4 4 4 0 Hemerythrin HHE cation binding domain Filament PF00038.16 EME86684.1 - 1.6 8.1 56.9 2.5 7.4 24.0 3.4 2 1 1 3 3 3 0 Intermediate filament protein Tropomyosin_1 PF12718.2 EME86684.1 - 1.6 8.5 68.8 7.1 6.4 1.1 5.4 2 1 2 5 5 5 0 Tropomyosin like Viral_P18 PF04521.8 EME86684.1 - 2.7 7.4 30.3 0.23 10.9 0.4 5.0 5 0 0 5 5 5 0 ssRNA positive strand viral 18kD cysteine rich protein ATG16 PF08614.6 EME86684.1 - 4.8 6.9 60.4 4.9 6.9 0.1 5.2 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EME86684.1 - 7.2 6.5 68.3 0.73 9.7 5.9 6.2 3 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding EHN PF06441.7 EME86686.1 - 1.8e-32 111.5 0.1 2.9e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EME86686.1 - 7.1e-07 29.0 0.6 0.0057 16.2 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME86686.1 - 0.00047 20.1 2.0 0.0075 16.1 0.7 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA PF00004.24 EME86687.1 - 3.1e-97 321.8 0.0 3.1e-47 160.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EME86687.1 - 6.1e-21 74.1 0.2 1.8e-20 72.6 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EME86687.1 - 7.2e-14 52.0 0.0 8.9e-08 32.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EME86687.1 - 2.3e-13 49.7 0.0 7.8e-06 25.1 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EME86687.1 - 1.2e-12 47.9 0.0 7.2e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME86687.1 - 1.1e-11 44.6 0.6 5.4e-06 26.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME86687.1 - 2.1e-11 44.1 0.2 0.0023 18.0 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EME86687.1 - 3e-11 43.6 0.0 0.00085 19.3 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EME86687.1 - 4.7e-11 43.5 0.0 0.00046 20.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EME86687.1 - 5.1e-09 35.3 0.6 0.00096 17.9 0.0 2.8 3 0 0 3 3 2 2 TIP49 C-terminus AAA_25 PF13481.1 EME86687.1 - 3.2e-08 33.1 4.5 0.031 13.6 0.0 4.6 3 2 1 5 5 4 2 AAA domain IstB_IS21 PF01695.12 EME86687.1 - 7.5e-08 31.9 0.0 0.0064 15.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EME86687.1 - 8.5e-08 31.8 1.5 0.004 16.8 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 EME86687.1 - 1.4e-07 31.5 0.0 0.0036 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EME86687.1 - 3.2e-07 29.7 0.8 0.03 13.4 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EME86687.1 - 4.2e-07 29.2 0.1 0.0075 15.3 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin RNA_helicase PF00910.17 EME86687.1 - 6.1e-07 29.5 0.0 0.026 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 EME86687.1 - 6.8e-07 28.6 0.9 0.36 9.9 0.0 3.5 2 1 1 3 3 3 2 KaiC CDC48_2 PF02933.12 EME86687.1 - 1e-06 28.2 0.0 2.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ResIII PF04851.10 EME86687.1 - 4.2e-06 26.7 0.0 0.0039 17.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EME86687.1 - 4.3e-06 27.0 0.0 0.069 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EME86687.1 - 6.3e-06 25.9 0.3 0.16 11.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EME86687.1 - 1.2e-05 25.2 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EME86687.1 - 1.4e-05 24.1 0.0 0.017 14.0 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EME86687.1 - 2.4e-05 23.3 0.1 0.082 11.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EME86687.1 - 2.9e-05 24.4 0.0 0.35 11.1 0.0 4.0 3 1 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.21 EME86687.1 - 3.2e-05 23.4 0.1 0.3 10.5 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EME86687.1 - 4.2e-05 23.3 0.1 7.7 6.1 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EME86687.1 - 7.2e-05 22.8 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EME86687.1 - 9.6e-05 21.7 0.3 0.3 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.13 EME86687.1 - 0.0001 22.0 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 EME86687.1 - 0.00026 20.6 0.1 0.63 9.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 EME86687.1 - 0.00041 19.9 0.0 0.92 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EME86687.1 - 0.00051 19.1 0.0 0.63 8.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 EME86687.1 - 0.00056 19.7 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_30 PF13604.1 EME86687.1 - 0.00067 19.2 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EME86687.1 - 0.00071 19.2 0.0 0.9 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EME86687.1 - 0.0018 17.2 0.1 0.75 8.5 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain NTPase_1 PF03266.10 EME86687.1 - 0.0029 17.3 0.3 1 9.0 0.0 3.5 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 EME86687.1 - 0.0054 16.2 0.0 0.56 9.6 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase Zot PF05707.7 EME86687.1 - 0.011 15.2 0.2 12 5.3 0.1 4.1 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 EME86687.1 - 0.012 14.6 0.2 0.97 8.3 0.0 3.0 2 2 0 3 3 3 0 KAP family P-loop domain IPT PF01745.11 EME86687.1 - 0.026 13.6 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EME86687.1 - 0.029 13.2 0.0 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EME86687.1 - 0.079 12.3 0.4 7.4 5.9 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 EME86687.1 - 0.15 11.6 0.1 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pro-kuma_activ PF09286.6 EME86689.1 - 5.9e-23 81.4 0.0 1.7e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EME86689.1 - 0.0031 16.7 0.1 0.0076 15.4 0.1 1.4 1 1 0 1 1 1 1 Subtilase family CorA PF01544.13 EME86690.1 - 0.00027 20.0 6.7 0.00047 19.2 4.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 EME86690.1 - 0.04 12.3 0.2 0.056 11.9 0.1 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 DUF4200 PF13863.1 EME86690.1 - 1.7 8.5 6.8 3.1 7.7 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RyR PF02026.11 EME86691.1 - 1.5e-10 40.9 0.1 6.5e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 RyR domain ATP-synt_ab_C PF00306.22 EME86691.1 - 0.0063 16.9 0.2 0.03 14.8 0.1 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Intg_mem_TP0381 PF09529.5 EME86692.1 - 0.0059 15.8 0.1 0.0077 15.4 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF4336 PF14234.1 EME86693.1 - 4.4e-07 29.3 0.0 0.17 11.0 0.0 3.0 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) Molybdopterin PF00384.17 EME86696.1 - 2.3e-71 240.8 0.0 9.6e-70 235.4 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EME86696.1 - 1.9e-20 72.4 0.7 1e-19 70.1 0.1 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EME86696.1 - 4.9e-19 67.2 0.1 1.4e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EME86696.1 - 3.9e-14 52.5 0.0 9.5e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EME86696.1 - 1.2e-08 34.5 0.4 1.2e-08 34.5 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EME86696.1 - 0.00072 19.3 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EME86696.1 - 0.11 12.1 1.0 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EME86696.1 - 0.16 11.8 1.8 3.2 7.6 1.2 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Proteasome PF00227.21 EME86697.1 - 2.7e-47 160.5 0.0 3.7e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME86697.1 - 6.9e-12 44.4 0.3 1.3e-11 43.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EME86697.1 - 0.036 13.7 1.2 13 5.5 0.0 3.0 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.9 EME86698.1 - 2.4e-43 146.7 7.6 2.6e-43 146.5 5.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 GtrA PF04138.9 EME86698.1 - 0.71 9.8 6.9 2.9 7.8 4.8 1.8 1 1 0 1 1 1 0 GtrA-like protein DUF4345 PF14248.1 EME86699.1 - 1.1 8.7 10.6 2 7.8 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4345) DUF3722 PF12519.3 EME86700.1 - 4.1e-85 285.1 0.0 5.1e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EME86700.1 - 1.8e-05 24.1 0.0 0.072 12.3 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic porin Peptidase_M43 PF05572.8 EME86702.1 - 7.4e-13 48.3 1.2 7.9e-13 48.2 0.1 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EME86702.1 - 2.2e-07 31.0 0.7 3.3e-07 30.4 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EME86702.1 - 7.1e-05 23.3 0.4 0.00015 22.3 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EME86702.1 - 0.00023 21.2 3.1 0.00034 20.7 2.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EME86702.1 - 0.00067 19.2 2.8 0.00094 18.7 0.3 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EME86702.1 - 0.007 16.0 0.1 0.011 15.4 0.0 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EME86702.1 - 0.16 10.8 4.2 0.091 11.6 1.0 1.7 2 0 0 2 2 2 0 Peptidase M66 Spb1_C PF07780.7 EME86703.1 - 5e-69 232.0 25.1 5e-69 232.0 17.4 4.0 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 EME86703.1 - 2.1e-52 177.7 0.0 3.9e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EME86703.1 - 3.4e-49 166.4 13.7 3.4e-49 166.4 9.5 4.8 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Asp_protease_2 PF13650.1 EME86705.1 - 2.8e-08 34.1 0.0 5.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EME86705.1 - 0.00019 21.3 0.1 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EME86705.1 - 0.011 15.4 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 EME86705.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase F-box PF00646.28 EME86706.1 - 3.5e-07 29.7 0.0 8.5e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME86706.1 - 1.6e-06 27.7 1.6 6.4e-06 25.7 0.1 2.7 3 0 0 3 3 3 1 F-box-like PPV_E1_C PF00519.12 EME86706.1 - 0.0091 14.6 0.3 0.71 8.4 0.0 2.1 1 1 1 2 2 2 2 Papillomavirus helicase PRK PF00485.13 EME86707.1 - 0.045 13.3 2.7 0.05 13.1 0.9 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TIP120 PF08623.5 EME86708.1 - 7.2e-53 178.6 0.9 3.2e-51 173.2 0.1 3.7 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EME86708.1 - 1.9e-15 56.9 28.7 0.00012 22.3 0.1 9.3 9 1 2 11 11 11 6 HEAT repeats HEAT PF02985.17 EME86708.1 - 1.2e-13 49.8 15.9 0.048 13.7 0.0 11.6 13 0 0 13 13 13 6 HEAT repeat HEAT_EZ PF13513.1 EME86708.1 - 3.2e-07 30.6 31.5 0.57 10.7 0.1 12.4 13 1 1 14 14 14 3 HEAT-like repeat DUF2435 PF10363.4 EME86708.1 - 1.2e-06 28.3 9.6 0.014 15.3 0.0 6.2 6 1 1 7 7 7 2 Protein of unknown function (DUF2435) DUF1546 PF07571.8 EME86708.1 - 0.00053 20.0 0.4 1 9.4 0.0 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF1546) RICTOR_N PF14664.1 EME86708.1 - 0.018 13.6 1.2 1.3 7.5 0.0 3.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term ADH_zinc_N PF00107.21 EME86709.1 - 9.8e-22 76.8 0.1 1.8e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME86709.1 - 1.5e-17 63.3 1.8 2.1e-17 62.8 0.6 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EME86709.1 - 0.039 13.9 0.2 0.084 12.8 0.1 1.5 1 1 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EME86709.1 - 0.11 11.8 0.8 0.2 11.0 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Kinetochor_Ybp2 PF08568.5 EME86710.1 - 1.8e-118 396.5 0.3 2.7e-118 395.9 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Macoilin PF09726.4 EME86710.1 - 0.38 8.9 13.8 0.48 8.6 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_72 PF03198.9 EME86712.1 - 1.1e-125 418.7 1.7 1.4e-125 418.4 1.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Sugar_tr PF00083.19 EME86713.1 - 1.2e-74 251.5 26.6 1.4e-74 251.3 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME86713.1 - 6.3e-21 74.4 36.9 9.2e-18 64.0 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME86713.1 - 7e-05 21.2 0.3 7e-05 21.2 0.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF805 PF05656.9 EME86714.1 - 0.07 12.9 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Fungal_trans PF04082.13 EME86715.1 - 7.3e-16 57.8 0.6 7.3e-16 57.8 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86715.1 - 8.2e-05 22.4 12.2 0.00014 21.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2_3 PF14378.1 EME86717.1 - 7.8e-18 64.6 20.5 7.5e-16 58.2 9.0 3.6 1 1 1 2 2 2 1 PAP2 superfamily Homeobox PF00046.24 EME86719.1 - 2.7e-19 68.5 3.9 5.4e-19 67.5 2.7 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EME86719.1 - 0.0018 17.9 0.4 0.004 16.8 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain DNA_pol_B PF00136.16 EME86720.1 - 7.9e-144 479.8 2.8 1.2e-143 479.3 1.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EME86720.1 - 2e-80 270.0 0.0 3.6e-80 269.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EME86720.1 - 2.8e-21 75.3 1.6 5.5e-21 74.3 1.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EME86720.1 - 0.00094 19.0 0.5 0.0043 16.8 0.3 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EME86720.1 - 0.0031 17.0 0.1 0.0092 15.5 0.0 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB JAB PF01398.16 EME86721.1 - 1.1e-27 96.0 0.4 2e-27 95.1 0.3 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EME86721.1 - 5.4e-09 35.5 0.4 2.1e-08 33.6 0.0 2.1 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EME86721.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF77 PF01910.12 EME86721.1 - 0.084 12.5 0.2 0.47 10.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF77 Fmp27 PF10344.4 EME86722.1 - 1.2e-183 612.2 0.0 1.9e-183 611.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EME86722.1 - 5.3e-158 526.6 1.2 5.3e-158 526.6 0.8 2.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EME86722.1 - 1.3e-142 475.5 1.4 1.3e-142 475.5 1.0 3.1 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EME86722.1 - 1.7e-54 183.9 0.1 5.9e-54 182.2 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EME86722.1 - 1.4e-47 161.3 0.7 4.2e-47 159.8 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EME86722.1 - 2e-28 98.8 0.9 1.3e-27 96.2 0.0 2.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apc4 PF12896.2 EME86723.1 - 0.023 13.9 0.2 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Adap_comp_sub PF00928.16 EME86724.1 - 1e-17 64.0 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EME86724.1 - 1.1e-06 28.4 0.1 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2420 PF10336.4 EME86725.1 - 1.2e-13 50.5 0.1 2.1e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mo-co_dimer PF03404.11 EME86726.1 - 2.6e-53 179.1 0.1 4.9e-53 178.2 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EME86726.1 - 6.8e-49 165.5 0.0 1.4e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EME86726.1 - 3.8e-28 97.5 0.0 6.5e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EME86726.1 - 5.2e-24 84.9 0.0 1.4e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EME86726.1 - 7e-22 77.0 0.0 1.4e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EME86726.1 - 0.00061 19.7 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 EME86727.1 - 5.7e-31 107.0 0.0 1.2e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EME86727.1 - 1.9e-27 96.4 0.8 3.9e-27 95.4 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EME86727.1 - 4.8e-18 64.7 0.0 2.2e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 EME86727.1 - 8.2e-15 54.9 6.9 1.3e-13 51.1 0.5 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EME86727.1 - 3.4e-13 48.9 0.0 1.2e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.10 EME86727.1 - 2.4e-10 40.3 5.8 7.7e-09 35.4 2.0 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 EME86727.1 - 4.9e-10 38.8 0.0 1.6e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EME86727.1 - 8.5e-08 32.5 0.1 0.0085 16.1 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME86727.1 - 5e-05 22.3 1.1 0.16 10.8 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME86727.1 - 0.00091 19.0 2.3 3.1 7.5 0.0 3.9 2 2 2 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EME86727.1 - 0.007 15.3 0.0 0.22 10.3 0.0 2.4 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GFO_IDH_MocA PF01408.17 EME86728.1 - 1.1e-24 87.2 0.0 1.8e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EME86728.1 - 0.0036 17.7 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glyoxalase PF00903.20 EME86728.1 - 0.062 13.2 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GFO_IDH_MocA_C PF02894.12 EME86728.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.12 EME86728.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M3 PF01432.15 EME86729.1 - 1.3e-115 387.0 0.3 1.7e-115 386.7 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M3 UCH PF00443.24 EME86730.1 - 9.9e-53 178.9 0.0 1.4e-26 93.2 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME86730.1 - 1.4e-30 106.7 0.0 1e-14 54.7 0.0 3.0 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase IBN_N PF03810.14 EME86730.1 - 0.029 14.2 0.3 0.53 10.2 0.0 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain Prim_Zn_Ribbon PF08273.7 EME86730.1 - 2.5 8.2 14.9 5.6 7.1 0.4 4.4 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase Sugar_tr PF00083.19 EME86733.1 - 6.2e-88 295.3 23.8 7.7e-88 295.0 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME86733.1 - 8.5e-35 120.0 34.5 8e-24 83.9 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EME86733.1 - 0.025 14.3 3.1 3.1 7.6 0.0 3.2 3 1 0 3 3 3 0 MFS_1 like family DUF2422 PF10337.4 EME86733.1 - 0.43 9.3 2.4 9 4.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) Glyco_hydro_2_C PF02836.12 EME86734.1 - 5.7e-97 324.1 0.1 8.2e-97 323.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EME86734.1 - 1e-51 174.8 0.1 2.9e-51 173.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 EME86734.1 - 1.2e-49 168.8 0.0 2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 EME86734.1 - 9.2e-13 48.6 0.1 3.2e-12 46.8 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Sec23_helical PF04815.10 EME86735.1 - 0.019 14.3 0.1 0.095 12.1 0.1 1.9 2 0 0 2 2 2 0 Sec23/Sec24 helical domain MFS_1 PF07690.11 EME86737.1 - 1.6e-27 96.2 34.9 1.6e-27 96.2 24.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86737.1 - 5.8e-09 35.0 23.8 3.6e-08 32.4 9.6 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EME86737.1 - 1.4e-08 33.4 20.0 4.6e-08 31.7 13.9 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EME86737.1 - 0.049 13.6 1.7 0.15 12.0 0.1 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF872 PF05915.7 EME86737.1 - 0.51 10.2 3.4 25 4.7 0.0 3.3 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Zn_clus PF00172.13 EME86738.1 - 6.7e-06 25.9 5.3 6.7e-06 25.9 3.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 EME86738.1 - 0.38 10.3 7.8 2.7 7.6 5.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) ketoacyl-synt PF00109.21 EME86739.1 - 9.2e-75 251.3 0.1 9.2e-75 251.3 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EME86739.1 - 3e-58 196.4 0.3 7.8e-58 195.1 0.2 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EME86739.1 - 1.1e-49 169.4 0.1 2.2e-49 168.5 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EME86739.1 - 8e-48 163.0 0.0 1.6e-47 162.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EME86739.1 - 5.1e-44 150.1 1.3 9.7e-44 149.2 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EME86739.1 - 7.4e-37 125.8 0.3 5e-36 123.1 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EME86739.1 - 6.4e-07 28.6 0.1 1.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EME86739.1 - 1.5e-06 28.3 0.0 4.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EME86739.1 - 1.2e-05 24.8 0.0 4.4e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME86739.1 - 0.0052 16.5 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F420_oxidored PF03807.12 EME86739.1 - 0.016 15.6 0.4 0.44 11.0 0.1 3.2 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent ACP_syn_III PF08545.5 EME86739.1 - 0.067 12.8 2.6 0.33 10.6 0.6 3.1 3 1 0 3 3 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Macro_2 PF14519.1 EME86739.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Macro-like domain FSH1 PF03959.8 EME86740.1 - 1.2e-18 67.3 0.1 5.9e-17 61.8 0.1 2.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EME86740.1 - 0.00032 20.6 0.0 0.00055 19.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family HTH_10 PF04967.7 EME86740.1 - 0.048 13.2 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain FSH1 PF03959.8 EME86741.1 - 3.7e-34 118.0 0.0 5.6e-34 117.4 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EME86741.1 - 2.1e-10 40.8 0.2 1.5e-07 31.5 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86741.1 - 6.4e-06 25.9 0.0 8.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME86741.1 - 2.3e-05 23.9 0.0 0.00063 19.2 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase RPE65 PF03055.10 EME86742.1 - 1.6e-109 366.6 0.0 1.8e-109 366.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pyr_redox_3 PF13738.1 EME86743.1 - 9e-17 61.7 0.0 3.9e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME86743.1 - 4e-16 58.3 0.1 7.8e-16 57.3 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EME86743.1 - 4.4e-10 39.4 0.0 6.6e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME86743.1 - 5.9e-09 35.2 0.0 2.1e-05 23.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AATase PF07247.7 EME86744.1 - 1e-29 103.4 0.0 1.4e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EME86744.1 - 6.4e-05 21.9 0.0 0.0019 17.1 0.0 2.1 2 0 0 2 2 2 2 Condensation domain DSPc PF00782.15 EME86745.1 - 8.2e-10 38.3 0.0 1.7e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME86745.1 - 2.4e-05 23.8 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EME86745.1 - 0.034 14.4 0.3 0.081 13.1 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Pheromone PF08015.6 EME86745.1 - 0.077 13.8 3.4 15 6.5 0.0 2.9 2 1 0 2 2 2 0 Fungal mating-type pheromone Cellulose_synt PF03552.9 EME86745.1 - 0.11 10.7 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase V-SNARE_C PF12352.3 EME86746.1 - 3.9e-14 52.4 0.3 1.2e-13 50.9 0.2 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EME86746.1 - 2.5e-07 30.2 0.1 8.5e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Sec20 IncA PF04156.9 EME86746.1 - 7.4 6.1 5.8 1.2 8.6 1.0 1.8 2 0 0 2 2 2 0 IncA protein BetaGal_dom4_5 PF13364.1 EME86747.1 - 2.8e-07 30.7 0.0 5.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Upf2 PF04050.9 EME86749.1 - 2e-51 174.1 12.8 2e-51 174.1 8.9 2.7 2 0 0 2 2 2 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EME86749.1 - 2.6e-45 154.4 0.3 3.7e-25 88.5 0.1 4.2 3 1 1 4 4 4 4 MIF4G domain AA_permease_2 PF13520.1 EME86750.1 - 1e-49 169.2 52.7 1.4e-49 168.8 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86750.1 - 5.6e-16 57.9 47.4 1.6e-15 56.4 32.9 1.6 1 1 0 1 1 1 1 Amino acid permease Arylsulfotran_2 PF14269.1 EME86751.1 - 1.2e-56 192.0 1.9 1.8e-56 191.5 1.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME86751.1 - 1.1e-13 50.5 3.1 2.3e-13 49.4 2.1 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF1127 PF06568.6 EME86752.1 - 7.1 6.1 8.5 3.5 7.1 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) CfAFP PF05264.6 EME86754.1 - 0.055 13.2 2.4 0.1 12.3 1.7 1.3 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) VPS28 PF03997.7 EME86754.1 - 0.12 11.9 0.0 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 VPS28 protein SnoaL_2 PF12680.2 EME86755.1 - 0.00011 22.5 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EME86755.1 - 0.00028 20.4 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 EME86755.1 - 0.05 13.6 0.1 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Gal4_dimer PF03902.8 EME86755.1 - 0.13 12.1 0.1 0.79 9.6 0.0 2.1 1 1 1 2 2 2 0 Gal4-like dimerisation domain Zn_clus PF00172.13 EME86756.1 - 9.6e-08 31.8 8.7 1.6e-07 31.1 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EME86756.1 - 0.002 16.8 1.5 0.0029 16.2 0.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EME86757.1 - 9.9e-15 55.0 1.9 1.5e-14 54.4 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EME86757.1 - 9.7e-12 44.6 1.4 2.3e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.2 EME86757.1 - 2.6e-09 36.9 0.5 5.3e-09 35.9 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME86757.1 - 2.3e-05 23.7 0.2 0.00031 20.0 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EME86757.1 - 3.8e-05 23.0 0.1 0.0043 16.3 0.1 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EME86757.1 - 0.0012 18.4 0.1 0.0027 17.2 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EME86757.1 - 0.0013 17.6 0.0 0.0026 16.6 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME86757.1 - 0.0053 15.5 0.0 0.0087 14.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.8 EME86757.1 - 0.06 12.9 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold NmrA PF05368.8 EME86758.1 - 9.8e-26 90.4 0.0 1.8e-25 89.6 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME86758.1 - 7.9e-18 65.1 0.2 1.5e-17 64.2 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME86758.1 - 0.0039 15.9 0.0 0.007 15.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME86758.1 - 0.0067 15.8 0.0 0.074 12.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EME86758.1 - 0.022 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EME86758.1 - 0.058 12.2 0.1 0.38 9.5 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EME86758.1 - 0.098 12.3 0.1 0.33 10.5 0.1 1.8 1 1 0 1 1 1 0 KR domain DFP PF04127.10 EME86758.1 - 0.16 11.5 1.3 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein RhgB_N PF09284.5 EME86760.1 - 7.8e-110 366.0 5.2 1.2e-109 365.5 3.6 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EME86760.1 - 1.1e-45 155.3 0.0 2.1e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EME86760.1 - 4.4e-17 61.9 0.8 1.1e-16 60.7 0.6 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EME86760.1 - 0.0034 17.4 0.5 0.025 14.6 0.2 2.7 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 EME86760.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Baculo_11_kDa PF06143.6 EME86762.1 - 0.066 12.5 0.7 0.07 12.4 0.5 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family HTH_38 PF13936.1 EME86763.1 - 8.1e-09 34.9 5.2 0.0042 16.6 0.0 3.9 4 0 0 4 4 4 3 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EME86763.1 - 2e-08 33.5 1.2 0.0052 16.2 0.1 4.9 5 0 0 5 5 5 1 Sigma-70, region 4 HTH_23 PF13384.1 EME86763.1 - 4e-08 32.6 6.0 0.15 11.7 0.0 5.2 4 1 1 5 5 5 3 Homeodomain-like domain Myb_DNA-bind_6 PF13921.1 EME86763.1 - 4.2e-08 33.1 3.3 0.061 13.4 0.1 4.5 3 2 1 4 4 4 2 Myb-like DNA-binding domain GerE PF00196.14 EME86763.1 - 3.4e-05 23.0 1.8 1.7 7.9 0.1 3.6 3 0 0 3 3 3 3 Bacterial regulatory proteins, luxR family HTH_24 PF13412.1 EME86763.1 - 3.8e-05 22.9 1.5 0.86 9.0 0.4 3.7 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.11 EME86763.1 - 0.00038 19.7 6.0 0.025 13.8 0.2 4.2 4 1 0 4 4 4 1 Sigma-70, region 4 HTH_11 PF08279.7 EME86763.1 - 0.00073 19.1 2.5 0.003 17.1 0.2 3.0 4 0 0 4 4 4 1 HTH domain HTH_7 PF02796.10 EME86763.1 - 0.0015 18.3 0.4 1.9 8.3 0.0 3.6 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_20 PF12840.2 EME86763.1 - 0.0038 17.0 0.1 0.36 10.6 0.0 3.3 4 0 0 4 4 3 1 Helix-turn-helix domain MarR_2 PF12802.2 EME86763.1 - 0.013 15.2 2.1 0.15 11.7 0.0 3.1 3 0 0 3 3 3 0 MarR family HTH_28 PF13518.1 EME86763.1 - 0.027 14.4 1.0 15 5.7 0.1 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain TrmB PF01978.14 EME86763.1 - 0.041 13.5 1.5 3.4 7.4 0.1 3.2 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_Tc3_1 PF11427.3 EME86763.1 - 0.063 12.9 4.1 4.8 6.8 0.1 3.6 4 0 0 4 4 4 0 Tc3 transposase OLF PF02191.11 EME86763.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Olfactomedin-like domain HTH_19 PF12844.2 EME86763.1 - 0.7 9.9 3.7 41 4.3 0.3 4.0 5 0 0 5 5 4 0 Helix-turn-helix domain Catalase PF00199.14 EME86765.1 - 9.9e-42 142.9 0.1 2.4e-41 141.7 0.0 1.5 1 1 0 1 1 1 1 Catalase BTB PF00651.26 EME86766.1 - 0.03 14.3 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 BTB/POZ domain Pkinase PF00069.20 EME86767.1 - 5.1e-12 45.4 0.0 1.8e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME86767.1 - 0.00022 20.4 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME86767.1 - 0.012 14.5 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like dUTPase PF00692.14 EME86768.1 - 9.5e-12 44.4 0.0 1.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.3 EME86768.1 - 0.083 12.9 0.0 0.22 11.5 0.0 1.7 1 1 1 2 2 2 0 FtsZ family, C-terminal domain APOC4 PF15119.1 EME86769.1 - 0.058 13.3 0.4 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Apolipoprotein C4 RhoGAP PF00620.22 EME86771.1 - 1.7e-44 151.1 0.0 1.2e-43 148.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EME86771.1 - 2.1e-13 50.2 0.4 7.1e-13 48.5 0.3 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sec23_trunk PF04811.10 EME86771.1 - 0.14 11.5 0.3 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain Pyridox_oxidase PF01243.15 EME86772.1 - 2.2e-11 43.6 0.0 1.3e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EME86772.1 - 0.029 14.1 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Rpp20 PF12328.3 EME86773.1 - 1e-32 112.7 11.5 2.3e-32 111.6 8.0 1.5 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EME86773.1 - 8.4e-20 70.1 0.4 1.9e-19 68.9 0.3 1.6 1 0 0 1 1 1 1 Alba BPL_LplA_LipB PF03099.14 EME86774.1 - 4.2e-16 59.0 0.0 8.5e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ADH_zinc_N PF00107.21 EME86775.1 - 1.4e-21 76.3 0.1 2.4e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME86775.1 - 2.3e-21 75.5 0.1 6.4e-21 74.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.9 EME86775.1 - 0.11 11.8 2.0 0.11 11.8 0.3 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EME86775.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_28 PF00295.12 EME86776.1 - 8.2e-108 360.2 19.9 9.8e-108 359.9 13.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PAPS_reduct PF01507.14 EME86778.1 - 8.5e-44 149.4 0.0 1.1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MFS_1 PF07690.11 EME86780.1 - 3e-34 118.2 25.6 1.4e-33 116.0 16.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86780.1 - 8.8e-11 41.0 11.2 8.8e-11 41.0 7.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EME86781.1 - 1.4e-43 148.9 30.6 1.4e-43 148.9 21.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86781.1 - 8e-18 64.2 21.0 3.9e-17 61.9 14.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.16 EME86781.1 - 0.028 14.2 0.2 0.028 14.2 0.1 4.4 3 1 2 5 5 5 0 FtsX-like permease family COX7C PF02935.11 EME86781.1 - 4.5 7.1 6.7 1 9.2 0.1 3.3 5 0 0 5 5 5 0 Cytochrome c oxidase subunit VIIc HET PF06985.6 EME86782.1 - 8.5e-30 103.7 0.1 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EGF_2 PF07974.8 EME86783.1 - 0.87 9.8 7.3 2.3 8.4 5.1 1.7 1 1 0 1 1 1 0 EGF-like domain EHN PF06441.7 EME86785.1 - 2.2e-09 37.1 0.0 3.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EME86785.1 - 7.1e-08 32.6 0.1 2e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86785.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family SNARE PF05739.14 EME86786.1 - 7.4e-17 60.8 1.4 7.4e-17 60.8 1.0 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EME86786.1 - 5.5e-14 52.1 4.1 2e-13 50.3 0.2 2.6 2 0 0 2 2 2 1 Syntaxin Syntaxin-18_N PF10496.4 EME86786.1 - 0.001 18.8 0.4 0.43 10.4 0.0 2.6 2 0 0 2 2 2 2 SNARE-complex protein Syntaxin-18 N-terminus ApoLp-III PF07464.6 EME86786.1 - 0.0072 16.3 4.7 2 8.4 0.0 2.5 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Reo_sigmaC PF04582.7 EME86786.1 - 0.084 12.0 0.4 4.8 6.2 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein LRS4 PF10422.4 EME86786.1 - 0.13 11.6 2.3 0.17 11.1 1.6 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Snapin_Pallidin PF14712.1 EME86786.1 - 0.28 11.5 6.8 3.6 7.9 0.5 3.4 3 0 0 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.7 EME86786.1 - 0.76 9.5 4.1 13 5.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 EME86786.1 - 0.81 9.6 5.5 0.65 9.9 0.1 2.5 1 1 2 3 3 3 0 Zinc finger-containing protein DUF16 PF01519.11 EME86786.1 - 4.5 7.5 8.6 16 5.7 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.7 EME86786.1 - 4.7 7.6 11.4 3.6 8.0 0.2 3.3 4 0 0 4 4 4 0 SlyX IATP PF04568.7 EME86788.1 - 0.55 10.2 3.7 0.65 10.0 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Zip PF02535.17 EME86789.1 - 0.0028 16.7 0.1 0.0032 16.5 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter adh_short PF00106.20 EME86790.1 - 3.9e-21 75.6 0.0 6.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME86790.1 - 3e-12 46.5 0.0 6e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME86790.1 - 1.9e-05 24.5 0.1 3e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EME86790.1 - 0.0046 17.0 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 EME86790.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DivIC PF04977.10 EME86790.1 - 0.039 13.4 0.4 0.067 12.6 0.0 1.5 2 0 0 2 2 2 0 Septum formation initiator Polysacc_synt_2 PF02719.10 EME86790.1 - 0.05 12.5 0.1 0.059 12.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2179 PF10035.4 EME86790.1 - 0.07 12.7 0.2 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF4239 PF14023.1 EME86790.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) MBA1 PF07961.6 EME86791.1 - 7.8e-09 34.7 0.0 8.3e-07 28.0 0.0 2.0 1 1 1 2 2 2 2 MBA1-like protein SUI1 PF01253.17 EME86792.1 - 9.2e-15 54.2 5.2 2.8e-09 36.6 0.6 2.2 1 1 1 2 2 2 2 Translation initiation factor SUI1 FHA PF00498.21 EME86792.1 - 0.086 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 FHA domain Nup35_RRM PF05172.8 EME86792.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 EME86795.1 - 2.5e-21 75.1 0.9 5.9e-15 54.7 0.0 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein SPT16 PF08644.6 EME86796.1 - 2.6e-58 196.2 3.2 3.1e-57 192.6 0.2 2.8 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EME86796.1 - 1.4e-50 171.0 0.4 1.4e-50 171.0 0.3 2.7 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EME86796.1 - 1.7e-26 93.0 0.0 3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EME86796.1 - 3.4e-21 75.0 0.0 1.5e-20 72.9 0.0 2.2 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Asp_Glu_race PF01177.17 EME86797.1 - 8.2e-28 97.7 1.1 5e-27 95.2 0.3 2.0 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.17 EME86797.1 - 1.7e-23 82.9 0.0 4.3e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EME86798.1 - 4.4e-25 88.0 0.3 1.2e-24 86.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME86798.1 - 1.4e-05 24.8 8.2 2.4e-05 24.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EME86800.1 - 1.1e-70 238.3 39.2 1.4e-70 238.1 27.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PHD PF00628.24 EME86801.1 - 1.3e-06 27.9 10.4 1.3e-06 27.9 7.2 1.6 2 0 0 2 2 2 1 PHD-finger VPS28 PF03997.7 EME86801.1 - 0.0083 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 VPS28 protein zf-PHD-like PF15446.1 EME86801.1 - 0.04 13.2 3.8 0.084 12.1 2.6 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EME86801.1 - 1.8 7.9 11.0 0.17 11.2 3.8 2.1 2 0 0 2 2 2 0 PHD-finger TF_Zn_Ribbon PF08271.7 EME86801.1 - 3.7 6.9 10.9 6.4 6.1 4.4 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Arb2 PF09757.4 EME86802.1 - 2.5e-14 53.0 0.0 4.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain GPI2 PF06432.6 EME86803.1 - 1.5e-113 378.8 2.7 1.8e-113 378.5 1.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF202 PF02656.10 EME86804.1 - 7.3e-14 51.7 0.9 7.3e-14 51.7 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF202) Form_Nir_trans PF01226.12 EME86805.1 - 1.3e-55 188.0 9.9 1.5e-55 187.8 6.8 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter NAD_binding_1 PF00175.16 EME86808.1 - 4.1e-23 82.0 0.0 6.4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME86808.1 - 2.2e-17 62.9 0.0 3.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EME86808.1 - 2.1e-07 30.9 0.0 1e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EME86808.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain GST_C_3 PF14497.1 EME86809.1 - 0.00036 20.9 0.1 0.00096 19.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME86809.1 - 0.0013 18.7 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME86809.1 - 0.0022 17.8 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_3 PF07859.8 EME86810.1 - 4.1e-50 170.2 0.0 5e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME86810.1 - 2.9e-09 36.1 0.2 1.3e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EME86810.1 - 7e-05 22.6 0.0 9.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME86810.1 - 0.0068 15.6 0.1 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 EME86810.1 - 0.07 11.6 0.0 0.21 10.0 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipocalin_5 PF13924.1 EME86811.1 - 4.1e-15 55.7 0.1 1.6e-14 53.8 0.1 1.9 1 1 0 1 1 1 1 Lipocalin-like domain IncA PF04156.9 EME86812.1 - 3.7e-07 29.9 33.3 8.6e-05 22.2 8.3 2.1 1 1 1 2 2 2 2 IncA protein Apolipoprotein PF01442.13 EME86812.1 - 1.6e-06 27.8 14.9 1.9e-05 24.2 10.1 2.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Tup_N PF08581.5 EME86812.1 - 7.1e-06 26.1 17.1 0.012 15.7 4.8 3.4 1 1 1 2 2 2 2 Tup N-terminal TPR_MLP1_2 PF07926.7 EME86812.1 - 1.2e-05 25.1 15.4 0.14 11.9 1.0 3.8 1 1 3 4 4 4 3 TPR/MLP1/MLP2-like protein Kinesin-related PF06548.6 EME86812.1 - 5.4e-05 21.9 6.2 0.036 12.6 0.3 3.4 1 1 3 4 4 4 2 Kinesin-related Filament PF00038.16 EME86812.1 - 6.6e-05 22.5 16.4 0.00016 21.2 11.4 1.7 1 1 0 1 1 1 1 Intermediate filament protein Streptin-Immun PF11083.3 EME86812.1 - 7.7e-05 22.6 11.7 0.11 12.5 0.2 3.0 1 1 2 3 3 3 3 Lantibiotic streptin immunity protein ApoO PF09769.4 EME86812.1 - 0.00012 21.7 6.0 0.06 13.0 0.2 3.2 1 1 2 3 3 3 1 Apolipoprotein O DUF3508 PF12018.3 EME86812.1 - 0.00017 20.7 6.9 0.00017 20.7 4.8 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3508) Tmemb_cc2 PF10267.4 EME86812.1 - 0.00025 19.7 13.4 0.0035 15.9 3.5 2.4 1 1 1 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein Phage_GP20 PF06810.6 EME86812.1 - 0.00031 20.2 19.3 0.019 14.4 6.4 2.6 1 1 2 3 3 3 3 Phage minor structural protein GP20 YlqD PF11068.3 EME86812.1 - 0.0011 18.9 20.6 0.66 10.0 7.7 3.0 1 1 1 2 2 2 2 YlqD protein DUF4407 PF14362.1 EME86812.1 - 0.0015 17.5 15.1 0.0023 16.9 10.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF515 PF04415.7 EME86812.1 - 0.0021 16.3 9.5 0.018 13.3 2.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF515) ORF11CD3 PF10549.4 EME86812.1 - 0.0023 17.6 0.9 5.6 6.7 0.0 4.3 3 1 0 4 4 4 0 ORF11CD3 domain DUF2479 PF10651.4 EME86812.1 - 0.0028 17.1 8.0 0.066 12.7 1.2 2.2 1 1 0 2 2 2 2 Domain of unknown function (DUF2479) ALMT PF11744.3 EME86812.1 - 0.0055 15.4 4.3 0.0062 15.2 2.2 1.4 1 1 0 1 1 1 1 Aluminium activated malate transporter Microvir_H PF04687.7 EME86812.1 - 0.0061 15.6 10.5 0.4 9.6 0.3 3.1 1 1 2 3 3 3 2 Microvirus H protein (pilot protein) CENP-F_leu_zip PF10473.4 EME86812.1 - 0.0094 15.8 12.8 0.53 10.1 3.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKK PF12474.3 EME86812.1 - 0.013 15.2 12.6 1.4 8.6 0.9 3.3 1 1 2 3 3 3 0 Polo kinase kinase IATP PF04568.7 EME86812.1 - 0.017 15.1 13.1 3.1 7.8 0.2 4.0 1 1 3 4 4 4 0 Mitochondrial ATPase inhibitor, IATP AphA_like PF14557.1 EME86812.1 - 0.022 14.3 6.1 1.2 8.7 0.4 2.2 1 1 0 2 2 2 0 Putative AphA-like transcriptional regulator Baculo_PEP_C PF04513.7 EME86812.1 - 0.025 14.4 14.3 0.037 13.8 4.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2939 PF11159.3 EME86812.1 - 0.027 14.6 9.6 8.6 6.6 0.1 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF2939) GrpB PF04229.9 EME86812.1 - 0.028 14.1 3.8 1.8 8.2 0.2 2.6 1 1 1 3 3 2 0 GrpB protein HR1 PF02185.11 EME86812.1 - 0.03 14.0 13.3 1.7 8.4 0.3 4.0 1 1 3 4 4 4 0 Hr1 repeat DUF4515 PF14988.1 EME86812.1 - 0.039 13.6 17.9 0.11 12.1 8.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) DUF3584 PF12128.3 EME86812.1 - 0.051 10.9 19.3 0.19 9.0 13.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1539 PF07560.6 EME86812.1 - 0.053 13.3 3.8 1.1 9.1 2.6 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Prefoldin_2 PF01920.15 EME86812.1 - 0.053 13.2 17.7 0.16 11.7 1.7 3.7 1 1 3 4 4 4 0 Prefoldin subunit AAA_13 PF13166.1 EME86812.1 - 0.057 11.8 14.2 0.071 11.5 9.9 1.1 1 0 0 1 1 1 0 AAA domain Kinetocho_Slk19 PF12709.2 EME86812.1 - 0.062 13.3 12.5 1.6 8.8 1.4 3.2 1 1 2 3 3 3 0 Central kinetochore-associated BAR_2 PF10455.4 EME86812.1 - 0.067 12.0 9.0 0.29 10.0 5.4 2.2 1 1 1 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4200 PF13863.1 EME86812.1 - 0.078 12.9 17.1 1.1 9.1 1.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) ERM PF00769.14 EME86812.1 - 0.086 12.3 13.4 0.14 11.6 9.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Lzipper-MIP1 PF14389.1 EME86812.1 - 0.087 12.9 15.6 5.6 7.1 5.1 4.8 1 1 2 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 SF-assemblin PF06705.6 EME86812.1 - 0.099 11.7 14.1 0.55 9.3 9.7 1.8 1 1 0 1 1 1 0 SF-assemblin/beta giardin Sds3 PF08598.6 EME86812.1 - 0.1 12.0 10.2 1.2 8.6 1.4 2.1 1 1 1 2 2 2 0 Sds3-like Med2 PF11214.3 EME86812.1 - 0.11 12.5 13.8 3.3 7.7 0.5 3.4 1 1 3 4 4 3 0 Mediator complex subunit 2 DUF1933 PF09147.5 EME86812.1 - 0.11 11.8 0.5 34 3.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1933) Malate_DH PF12434.3 EME86812.1 - 0.12 12.1 9.6 14 5.4 0.1 4.6 4 0 0 4 4 4 0 Malate dehydrogenase enzyme UBN2_2 PF14227.1 EME86812.1 - 0.14 11.6 1.1 15 5.1 0.1 2.6 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type PFEMP PF03011.10 EME86812.1 - 0.18 12.1 5.0 0.24 11.7 2.5 1.7 1 1 1 2 2 2 0 PFEMP DBL domain DUF2383 PF09537.5 EME86812.1 - 0.19 11.9 7.5 9 6.5 0.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF2383) DUF2077 PF09850.4 EME86812.1 - 0.2 11.0 10.9 2 7.7 0.2 3.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Cortex-I_coil PF09304.5 EME86812.1 - 0.21 11.6 15.6 90 3.1 10.8 2.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil DUF1640 PF07798.6 EME86812.1 - 0.27 11.2 12.4 1.3 9.0 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Mst1_SARAH PF11629.3 EME86812.1 - 0.27 11.0 6.9 19 5.2 0.0 4.0 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 Ax_dynein_light PF10211.4 EME86812.1 - 0.28 11.0 16.6 0.049 13.4 3.5 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain CENP-H PF05837.7 EME86812.1 - 0.29 11.3 11.8 9.1 6.5 2.5 3.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GrpE PF01025.14 EME86812.1 - 0.31 10.5 15.5 1.5 8.3 1.7 3.0 1 1 2 3 3 3 0 GrpE OmpH PF03938.9 EME86812.1 - 0.32 10.9 20.3 0.057 13.3 8.8 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 EME86812.1 - 0.33 10.9 12.3 2 8.4 2.9 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Adeno_PVIII PF01310.13 EME86812.1 - 0.34 10.6 1.9 0.49 10.1 1.3 1.2 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII BBP1_C PF15272.1 EME86812.1 - 0.4 10.2 16.9 3.2 7.2 8.1 2.5 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal Mnd1 PF03962.10 EME86812.1 - 0.42 10.2 16.5 0.91 9.1 4.9 2.1 1 1 1 2 2 2 0 Mnd1 family Pox_C7_F8A PF03287.9 EME86812.1 - 0.54 9.9 4.9 14 5.3 0.1 3.1 1 1 2 3 3 3 0 Poxvirus C7/F8A protein FlxA PF14282.1 EME86812.1 - 0.54 10.2 29.1 1.1 9.2 5.8 2.9 1 1 1 2 2 2 0 FlxA-like protein CCDC-167 PF15188.1 EME86812.1 - 0.59 10.1 11.8 3.4 7.6 1.5 3.4 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 COG5 PF10392.4 EME86812.1 - 0.61 10.0 10.1 1.5 8.7 2.4 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF2450 PF10475.4 EME86812.1 - 0.66 8.8 9.6 2.7 6.8 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Rabaptin PF03528.10 EME86812.1 - 0.69 9.8 16.4 1.3 8.9 5.6 2.6 1 1 1 2 2 2 0 Rabaptin FliD_C PF07195.7 EME86812.1 - 0.8 8.9 15.1 6.7 5.9 0.6 2.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Bap31 PF05529.7 EME86812.1 - 1.1 8.7 13.0 7.6 5.9 3.8 3.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF1706 PF08020.6 EME86812.1 - 1.1 8.6 5.4 9.6 5.6 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1706) RmuC PF02646.11 EME86812.1 - 1.6 7.4 13.0 0.85 8.4 2.2 2.0 2 0 0 2 2 2 0 RmuC family Atg14 PF10186.4 EME86812.1 - 1.8 7.4 18.1 8.7 5.1 12.6 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EME86812.1 - 1.9 8.6 17.1 0.99 9.5 1.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TSC22 PF01166.13 EME86812.1 - 2 8.4 9.6 18 5.3 0.5 4.1 1 1 1 3 3 3 0 TSC-22/dip/bun family CDC37_N PF03234.9 EME86812.1 - 3.2 8.0 12.0 7.4 6.8 8.1 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Halo_GVPC PF05465.8 EME86812.1 - 3.5 7.6 8.6 33 4.5 0.1 3.7 4 0 0 4 4 3 0 Halobacterial gas vesicle protein C (GVPC) repeat HSCB_C PF07743.8 EME86812.1 - 3.8 8.0 14.6 19 5.8 0.2 3.7 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain CR6_interact PF10147.4 EME86812.1 - 4.6 6.4 8.6 8.3 5.6 5.0 1.8 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Pro_CA PF00484.14 EME86812.1 - 4.7 7.1 9.0 9.5 6.2 1.9 2.4 1 1 1 2 2 2 0 Carbonic anhydrase DUF3154 PF11351.3 EME86812.1 - 5.6 6.7 9.5 6.2 6.5 0.8 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3154) Tho2 PF11262.3 EME86812.1 - 5.8 5.8 12.4 2.3 7.1 2.7 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ACCA PF03255.9 EME86812.1 - 7 6.1 10.4 10 5.6 0.7 2.8 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit KfrA_N PF11740.3 EME86812.1 - 8.4 6.8 17.7 6.1 7.3 0.6 3.4 1 1 3 4 4 4 0 Plasmid replication region DNA-binding N-term Spc24 PF08286.6 EME86812.1 - 8.6 6.0 17.9 2.8 7.6 1.7 3.1 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 TMPIT PF07851.8 EME86812.1 - 8.7 5.3 9.6 18 4.3 6.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein DUF3573 PF12097.3 EME86813.1 - 0.8 8.2 5.3 1.3 7.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Trehalase PF01204.13 EME86814.1 - 1.4e-123 413.3 3.0 2e-113 379.7 0.1 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EME86814.1 - 0.00016 20.5 0.0 0.00026 19.8 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF773 PF05600.7 EME86814.1 - 0.24 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Glyco_hydro_16 PF00722.16 EME86815.1 - 1.4e-34 118.9 4.5 2e-34 118.4 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 adh_short PF00106.20 EME86816.1 - 8.9e-21 74.5 0.0 1.2e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME86816.1 - 4.4e-13 49.5 0.0 5.6e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME86816.1 - 4.2e-10 39.5 0.0 5.7e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME86816.1 - 0.029 14.1 0.2 0.065 13.0 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4546 PF15079.1 EME86816.1 - 0.034 13.2 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4546) Epimerase PF01370.16 EME86816.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SH3_1 PF00018.23 EME86817.1 - 1.5e-05 24.2 0.0 3.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME86817.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AAA_13 PF13166.1 EME86818.1 - 0.034 12.6 7.3 0.052 12.0 5.1 1.2 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 EME86818.1 - 0.063 13.0 7.6 0.64 9.7 0.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Dynamitin PF04912.9 EME86818.1 - 0.084 11.6 7.9 0.14 10.9 2.6 2.2 1 1 1 2 2 2 0 Dynamitin DASH_Dam1 PF08653.5 EME86818.1 - 0.12 12.1 0.7 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 Seryl_tRNA_N PF02403.17 EME86818.1 - 0.49 10.4 7.5 1.6 8.7 0.9 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EME86818.1 - 0.66 9.5 6.9 10 5.6 4.8 2.3 1 1 0 1 1 1 0 IncA protein DinB PF05163.7 EME86818.1 - 0.77 9.4 6.0 2 8.1 1.4 2.3 1 1 1 2 2 2 0 DinB family Jnk-SapK_ap_N PF09744.4 EME86818.1 - 0.9 9.5 5.8 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.7 EME86818.1 - 1 9.8 4.4 3.1 8.2 1.3 2.9 2 1 0 2 2 2 0 SlyX TBPIP PF07106.8 EME86818.1 - 1.4 8.4 5.8 9 5.8 0.9 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MerR-DNA-bind PF09278.6 EME86818.1 - 3.3 8.1 12.0 12 6.4 2.5 3.3 3 1 0 3 3 3 0 MerR, DNA binding SPRY PF00622.23 EME86819.1 - 0.0011 19.0 0.0 0.018 15.1 0.0 2.7 2 2 1 3 3 3 1 SPRY domain Bystin PF05291.6 EME86820.1 - 1.9e-124 414.5 0.0 2.5e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 Bystin THRAP3_BCLAF1 PF15440.1 EME86820.1 - 0.28 9.7 3.7 0.34 9.5 2.6 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Ribonuc_red_sm PF00268.16 EME86821.1 - 1.7e-119 398.0 3.0 2e-119 397.7 2.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain WD40 PF00400.27 EME86823.1 - 9.4e-34 114.0 5.5 1.1e-10 40.9 0.1 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EME86823.1 - 0.00077 19.2 0.0 0.041 13.5 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Arylsulfotran_2 PF14269.1 EME86824.1 - 1.6e-78 263.8 0.9 2e-78 263.5 0.6 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF1469 PF07332.6 EME86828.1 - 0.0037 16.9 3.3 0.0069 16.1 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) Pkinase PF00069.20 EME86831.1 - 4.2e-55 186.7 0.0 6.5e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME86831.1 - 1.5e-30 106.1 0.0 2.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME86831.1 - 4.4e-10 38.9 0.0 2.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EME86831.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EME86831.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.1 EME86832.1 - 1.3e-23 84.0 0.0 1.6e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME86832.1 - 1.6e-05 24.4 0.0 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EME86832.1 - 0.00076 19.9 0.0 0.00093 19.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LINES_C PF14695.1 EME86832.1 - 0.12 11.6 0.1 0.94 8.7 0.0 2.2 2 0 0 2 2 2 0 Lines C-terminus p450 PF00067.17 EME86833.1 - 1.6e-57 195.0 0.0 2.1e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_A PF00476.15 EME86835.1 - 5.6e-101 337.9 0.0 8e-101 337.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EME86835.1 - 0.021 14.3 0.1 1.1 8.6 0.0 2.7 3 0 0 3 3 3 0 3'-5' exonuclease zf-C3HC4_3 PF13920.1 EME86836.1 - 2.9e-09 36.4 9.5 6.2e-09 35.3 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME86836.1 - 4.8e-09 35.9 9.6 1.4e-08 34.4 6.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EME86836.1 - 4.4e-08 33.0 9.8 1.4e-07 31.4 6.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME86836.1 - 6.7e-07 28.9 10.7 1.7e-06 27.6 7.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EME86836.1 - 1.7e-05 24.3 10.1 4.8e-05 22.9 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME86836.1 - 0.0091 15.8 8.7 0.026 14.4 6.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME86836.1 - 0.098 12.3 7.4 0.13 11.9 1.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EME86836.1 - 0.19 11.7 6.9 0.45 10.4 4.8 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EME86836.1 - 0.24 10.9 10.2 2.5 7.7 3.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EME86836.1 - 0.42 10.2 8.0 0.98 9.0 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.11 EME86836.1 - 0.53 10.1 5.1 1.1 9.1 3.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger TRAM_LAG1_CLN8 PF03798.11 EME86839.1 - 3.9e-35 121.2 19.4 3.9e-35 121.2 13.4 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EME86839.1 - 3.3e-23 80.9 0.0 8e-23 79.7 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein PIF1 PF05970.9 EME86840.1 - 5.3e-12 45.3 0.0 3.9e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase UvrD_C_2 PF13538.1 EME86840.1 - 1.3e-05 25.2 0.0 0.0001 22.3 0.0 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EME86840.1 - 0.00025 18.9 0.1 0.00044 18.1 0.0 1.3 1 1 0 1 1 1 1 Helicase CorA PF01544.13 EME86841.1 - 8.8e-26 90.6 10.3 1.2e-20 73.7 5.4 2.9 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Brr6_like_C_C PF10104.4 EME86841.1 - 0.062 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain ATP13 PF12921.2 EME86843.1 - 1.1e-26 92.6 0.0 3.2e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EME86843.1 - 0.0014 18.5 0.1 0.064 13.2 0.0 3.3 4 0 0 4 4 4 1 PPR repeat family PPR_3 PF13812.1 EME86843.1 - 0.0028 17.7 0.6 0.24 11.7 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EME86843.1 - 0.011 15.6 3.4 0.21 11.6 0.0 4.3 5 0 0 5 5 5 0 PPR repeat Hydrolase_2 PF07486.7 EME86843.1 - 0.059 13.8 0.3 0.17 12.4 0.2 1.7 1 0 0 1 1 1 0 Cell Wall Hydrolase PPR_1 PF12854.2 EME86843.1 - 0.15 11.5 0.2 1 8.8 0.0 2.6 3 0 0 3 3 3 0 PPR repeat LSM PF01423.17 EME86844.1 - 3.1e-18 65.0 0.2 4.4e-18 64.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain Gly-rich_Ago1 PF12764.2 EME86845.1 - 1.2 9.8 3.7 1.5 9.4 2.5 1.3 1 1 0 1 1 1 0 Glycine-rich region of argonaut AA_permease_2 PF13520.1 EME86846.1 - 3.8e-47 160.7 51.2 5e-47 160.3 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86846.1 - 1.1e-22 80.0 41.1 1.6e-22 79.5 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease BRCT PF00533.21 EME86847.1 - 0.043 13.9 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CENP-B_dimeris PF09026.5 EME86847.1 - 0.66 10.2 4.3 1.1 9.5 3.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 EME86847.1 - 3.2 7.4 6.0 4.9 6.8 4.2 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.7 EME86847.1 - 8.3 4.1 10.7 9.8 3.9 7.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 EME86847.1 - 8.4 6.3 11.7 12 5.8 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Polysacc_deac_1 PF01522.16 EME86848.1 - 1.2e-13 50.7 0.0 2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase MFS_1 PF07690.11 EME86849.1 - 1.3e-28 99.7 27.4 3.7e-18 65.3 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME86849.1 - 1.3e-10 40.2 13.6 5.3e-05 21.8 5.3 2.2 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EME86849.1 - 0.0095 14.5 21.4 0.047 12.2 7.7 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EME86849.1 - 0.011 15.5 4.9 0.011 15.4 0.2 3.0 3 0 0 3 3 3 0 MFS_1 like family HEAT_2 PF13646.1 EME86850.1 - 6.6e-16 58.3 31.3 0.00013 22.2 0.2 9.7 7 2 2 9 9 9 5 HEAT repeats HEAT PF02985.17 EME86850.1 - 4.8e-12 44.8 32.3 0.064 13.3 0.2 12.9 14 0 0 14 14 14 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EME86850.1 - 0.001 19.3 0.0 1.1 9.6 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EME86850.1 - 0.0029 17.3 12.0 0.98 9.3 0.0 7.1 6 1 1 7 7 7 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EME86850.1 - 0.012 15.4 2.2 11 5.8 0.0 5.9 8 1 0 8 8 8 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EME86850.1 - 3.5 8.2 28.0 2.9 8.4 0.3 9.2 7 2 3 10 10 10 0 HEAT-like repeat NIF PF03031.13 EME86851.1 - 4.2e-22 78.5 0.1 5.4e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPT PF03151.11 EME86852.1 - 7.2e-22 77.6 11.3 7.2e-22 77.6 7.8 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EME86852.1 - 2.7e-15 56.1 21.2 5e-15 55.2 14.7 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME86852.1 - 0.016 15.2 32.1 0.018 15.0 6.9 2.9 2 1 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 EME86852.1 - 0.47 10.6 27.1 0.043 14.0 6.1 3.2 1 1 1 3 3 3 0 Multidrug resistance efflux transporter Spo7 PF03907.8 EME86853.1 - 1.1e-59 201.6 0.0 1.3e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 EME86854.1 - 1.4e-30 106.8 0.5 2.6e-30 105.9 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME86854.1 - 1.2e-18 67.5 0.1 7.2e-18 64.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME86854.1 - 5.8e-13 48.8 0.0 3.7e-10 39.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EME86854.1 - 1.2e-06 28.1 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EME86854.1 - 1.9e-06 27.1 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EME86854.1 - 0.0052 17.0 0.2 0.061 13.5 0.1 2.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EME86854.1 - 0.0093 15.4 0.0 0.26 10.6 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EME86854.1 - 0.013 15.0 0.0 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF2048 PF09752.4 EME86854.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF900 PF05990.7 EME86854.1 - 0.035 13.4 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.3 EME86854.1 - 0.036 13.9 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 EME86854.1 - 0.041 13.4 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EME86854.1 - 0.05 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 EME86854.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 EME86854.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme 2-Hacid_dh_C PF02826.14 EME86856.1 - 8.7e-50 168.3 0.0 1.5e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME86856.1 - 7.7e-16 57.7 0.0 1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EME86856.1 - 0.0037 17.1 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EME86856.1 - 0.015 14.8 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrmE_N PF10396.4 EME86858.1 - 7.4e-34 116.1 0.0 2e-33 114.7 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EME86858.1 - 1.4e-21 76.6 0.2 4.6e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EME86858.1 - 1.3e-17 63.7 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_3_C PF01915.17 EME86858.1 - 2.1e-06 27.4 0.4 1.9e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Dynamin_N PF00350.18 EME86858.1 - 2.8e-06 27.2 0.0 5.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EME86858.1 - 0.00011 21.5 0.2 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EME86858.1 - 0.0013 19.2 0.0 0.0062 17.0 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EME86858.1 - 0.023 14.1 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EME86858.1 - 0.04 13.8 0.1 0.098 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EME86858.1 - 0.053 12.9 0.8 5.9 6.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain F-box-like PF12937.2 EME86859.1 - 0.027 14.1 0.1 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 EME86859.1 - 2.5 7.8 6.4 2 8.2 2.0 2.7 2 1 1 3 3 3 0 Leucine rich repeat Hus1 PF04005.7 EME86860.1 - 9.9e-99 329.9 0.0 1.2e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein FH2 PF02181.18 EME86861.1 - 8.8e-85 284.8 4.1 8.8e-85 284.8 2.9 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EME86861.1 - 1.3e-65 220.2 0.9 2.7e-65 219.2 0.1 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EME86861.1 - 6.3e-52 175.8 0.4 6.3e-52 175.8 0.3 3.7 3 1 1 4 4 4 2 Diaphanous FH3 Domain DUF4239 PF14023.1 EME86861.1 - 3.6 6.8 9.6 10 5.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) RabGAP-TBC PF00566.13 EME86862.1 - 2.4e-37 128.5 0.6 4.3e-37 127.6 0.4 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EME86862.1 - 7e-09 35.2 0.0 2.4e-07 30.2 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3548) WW PF00397.21 EME86864.1 - 1.7e-08 34.1 6.5 3.6e-08 33.1 4.5 1.6 1 0 0 1 1 1 1 WW domain Dehydrin PF00257.14 EME86864.1 - 0.00047 20.5 9.2 0.0014 19.0 6.3 1.9 1 1 0 1 1 1 1 Dehydrin CCDC50_N PF15295.1 EME86864.1 - 0.08 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus APC_CDC26 PF10471.4 EME86864.1 - 4.6 8.0 7.4 0.71 10.6 2.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PCI_Csn8 PF10075.4 EME86865.1 - 0.092 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Fes1 PF08609.5 EME86866.1 - 2.5e-28 98.4 2.4 2.5e-28 98.4 1.7 1.8 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EME86866.1 - 8e-07 29.2 8.1 0.00041 20.5 0.5 2.1 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 EME86866.1 - 3.3e-05 23.5 0.6 0.042 13.6 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EME86866.1 - 0.0033 17.8 1.8 0.032 14.7 0.1 2.9 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EME86866.1 - 0.03 14.3 0.1 8.9 6.6 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat Phe_tRNA-synt_N PF02912.13 EME86866.1 - 0.035 13.8 0.1 0.087 12.5 0.1 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Glyco_hydro_67M PF07488.7 EME86866.1 - 0.078 11.8 0.1 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Actin PF00022.14 EME86868.1 - 7.5e-159 528.3 0.0 8.5e-159 528.1 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EME86868.1 - 0.038 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DAO PF01266.19 EME86869.1 - 3e-43 148.0 0.2 6.2e-43 147.0 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME86869.1 - 0.0034 17.2 0.0 0.0072 16.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EME86869.1 - 0.084 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DAP_C PF07932.7 EME86870.1 - 3.6e-38 129.6 0.1 1.3e-37 127.8 0.1 2.0 2 0 0 2 2 2 1 D-aminopeptidase, domain C Beta-lactamase PF00144.19 EME86870.1 - 1.5e-36 126.0 0.0 2.6e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DAP_B PF07930.7 EME86870.1 - 0.0033 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 D-aminopeptidase, domain B Abhydrolase_4 PF08386.5 EME86871.1 - 5.6e-18 64.7 0.1 1.9e-17 62.9 0.1 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EME86871.1 - 4.6e-16 59.0 0.1 7.1e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME86871.1 - 3e-12 46.9 0.0 5.7e-12 45.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86871.1 - 0.00019 21.2 0.0 0.0017 18.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86874.1 - 1.7e-07 31.0 0.2 3.8e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME86874.1 - 0.0049 16.7 0.4 0.021 14.7 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME86874.1 - 0.0066 15.6 0.2 0.018 14.2 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EME86874.1 - 0.058 12.6 0.4 0.33 10.1 0.0 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase Lipase_GDSL_2 PF13472.1 EME86875.1 - 2.7e-11 43.9 0.2 4.4e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME86875.1 - 4.2e-10 39.8 0.2 2.6e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase WD40 PF00400.27 EME86876.1 - 3.8e-10 39.2 13.8 1.4e-06 27.9 0.0 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.3 EME86876.1 - 0.031 12.4 0.6 0.073 11.1 0.1 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EME86876.1 - 0.064 13.5 4.9 21 5.5 0.1 4.7 5 0 0 5 5 5 0 PQQ-like domain SGL PF08450.7 EME86876.1 - 0.1 11.9 0.0 0.49 9.7 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region TauD PF02668.11 EME86877.1 - 9.9e-45 153.2 0.1 1.2e-44 152.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease_2 PF13520.1 EME86878.1 - 2.4e-51 174.6 52.3 3e-51 174.3 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME86878.1 - 9.4e-15 53.8 43.5 1.3e-14 53.4 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4234 PF14018.1 EME86878.1 - 0.0012 18.5 0.2 0.0012 18.5 0.1 4.1 5 1 0 5 5 5 1 Domain of unknown function (DUF4234) FA_hydroxylase PF04116.8 EME86879.1 - 1.1e-14 54.8 7.4 1.1e-14 54.8 5.1 2.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Thioredoxin_8 PF13905.1 EME86879.1 - 0.081 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.1 EME86880.1 - 2.8e-07 30.6 0.1 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME86880.1 - 0.00019 21.2 0.0 0.00055 19.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME86880.1 - 0.00052 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_6 PF12697.2 EME86882.1 - 7.7e-13 48.8 0.1 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME86882.1 - 2.3e-05 24.1 0.0 3.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME86882.1 - 0.029 14.2 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_8 PF06259.7 EME86882.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase MFS_1 PF07690.11 EME86883.1 - 2.5e-22 79.0 14.3 3.5e-22 78.6 9.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME86883.1 - 5.2e-08 31.8 3.7 1.6e-06 26.9 1.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter 7tm_7 PF08395.7 EME86883.1 - 1.1 8.2 5.4 1 8.3 3.0 1.5 1 1 0 1 1 1 0 7tm Chemosensory receptor FYVE PF01363.16 EME86885.1 - 0.004 17.0 1.8 0.011 15.6 1.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_2 PF13639.1 EME86885.1 - 0.0047 16.7 3.4 0.012 15.3 2.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EME86885.1 - 0.02 14.5 0.5 0.053 13.2 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EME86885.1 - 0.26 11.0 3.6 0.61 9.8 2.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME86885.1 - 0.61 10.1 5.1 0.53 10.3 2.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME86885.1 - 0.93 9.2 5.0 1.9 8.1 2.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4446 PF14584.1 EME86885.1 - 7.5 6.3 10.1 6.8 6.5 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) PHD PF00628.24 EME86886.1 - 0.00022 20.8 7.4 0.00042 19.9 5.1 1.5 1 0 0 1 1 1 1 PHD-finger Pneumo_att_G PF05539.6 EME86886.1 - 7 5.9 11.7 8.8 5.5 8.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ORC6 PF05460.8 EME86886.1 - 7.8 5.4 11.7 6.3 5.7 7.5 1.3 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DSPc PF00782.15 EME86889.1 - 1.3e-10 40.9 0.1 1.8e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EME86889.1 - 0.00042 19.3 0.0 0.00045 19.2 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EME86889.1 - 0.11 11.8 0.3 0.15 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L1 PF00687.16 EME86890.1 - 3.7e-61 206.2 1.5 3.7e-61 206.2 1.1 1.7 3 0 0 3 3 3 1 Ribosomal protein L1p/L10e family DASH_Spc34 PF08657.5 EME86891.1 - 0.0063 16.2 1.2 0.83 9.2 0.2 2.2 2 0 0 2 2 2 2 DASH complex subunit Spc34 DUF2046 PF09755.4 EME86891.1 - 0.014 14.3 1.4 0.017 14.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Leu_zip PF15294.1 EME86891.1 - 0.015 14.4 0.7 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 Leucine zipper DUF2968 PF11180.3 EME86891.1 - 0.34 10.2 9.1 1.4 8.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.10 EME86891.1 - 0.43 10.1 0.1 0.43 10.1 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 EME86891.1 - 0.57 10.2 5.0 0.32 11.0 0.3 2.1 2 0 0 2 2 2 0 DivIVA protein MogR_DNAbind PF12181.3 EME86892.1 - 0.37 10.5 0.0 0.6 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Myb_DNA-bind_6 PF13921.1 EME86895.1 - 6.7e-18 64.5 1.3 0.00012 22.0 0.0 6.1 5 1 1 6 6 6 3 Myb-like DNA-binding domain HTH_38 PF13936.1 EME86895.1 - 8.4e-16 57.2 0.2 0.024 14.2 0.0 5.5 5 0 0 5 5 5 5 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EME86895.1 - 2.2e-12 46.2 2.6 0.005 16.2 0.0 5.3 5 0 0 5 5 5 2 Sigma-70, region 4 GcrA PF07750.6 EME86895.1 - 7.6e-09 35.9 5.9 0.0006 20.0 0.0 3.7 3 1 0 3 3 3 3 GcrA cell cycle regulator HTH_23 PF13384.1 EME86895.1 - 3.7e-07 29.5 7.7 3.5 7.4 0.1 5.6 6 0 0 6 6 6 4 Homeodomain-like domain Myb_DNA-binding PF00249.26 EME86895.1 - 8.7e-05 22.4 3.3 0.013 15.5 0.1 5.4 7 0 0 7 7 7 1 Myb-like DNA-binding domain HTH_20 PF12840.2 EME86895.1 - 0.01 15.5 1.2 10 6.0 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_28 PF13518.1 EME86895.1 - 0.012 15.5 2.3 12 6.0 0.0 4.4 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_11 PF08279.7 EME86895.1 - 0.017 14.7 2.0 11 5.7 0.1 3.4 3 0 0 3 3 3 0 HTH domain DNA_binding_1 PF01035.15 EME86895.1 - 0.022 14.5 0.5 6 6.6 0.0 3.4 4 0 0 4 4 4 0 6-O-methylguanine DNA methyltransferase, DNA binding domain GerE PF00196.14 EME86895.1 - 0.022 14.0 1.1 6.1 6.2 0.0 4.1 5 1 0 5 5 5 0 Bacterial regulatory proteins, luxR family HTH_AsnC-type PF13404.1 EME86895.1 - 0.094 12.2 6.6 4.7 6.8 0.3 4.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain UBX PF00789.15 EME86896.1 - 2.9e-09 36.8 0.0 5.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin PF00085.15 EME86896.1 - 0.032 13.8 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Nuc-transf PF10127.4 EME86896.1 - 0.08 12.2 2.2 3.6 6.8 2.1 2.1 2 0 0 2 2 2 0 Predicted nucleotidyltransferase SOBP PF15279.1 EME86896.1 - 0.25 11.7 6.2 0.38 11.0 4.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 EME86896.1 - 6.9 6.4 8.3 15 5.4 5.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tannase PF07519.6 EME86897.1 - 2.3e-109 366.2 1.1 3.5e-109 365.6 0.7 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EME86897.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME86897.1 - 0.00084 19.2 0.0 0.0018 18.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PH_4 PF15404.1 EME86899.1 - 0.029 13.9 1.3 0.036 13.5 0.9 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DAO PF01266.19 EME86901.1 - 4.1e-40 137.7 0.2 5.2e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME86901.1 - 0.00026 21.1 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME86901.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EME86901.1 - 0.0021 17.1 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EME86901.1 - 0.045 12.6 0.0 0.33 9.7 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain MFS_1 PF07690.11 EME86902.1 - 6.7e-16 57.9 31.1 3e-14 52.5 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EME86902.1 - 1.6e-05 24.4 5.9 1.8e-05 24.2 2.4 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1275 PF06912.6 EME86902.1 - 0.0018 17.5 0.0 0.0018 17.5 0.0 3.5 2 2 2 4 4 4 1 Protein of unknown function (DUF1275) PUCC PF03209.10 EME86902.1 - 0.019 13.7 5.0 0.04 12.6 3.5 1.6 1 0 0 1 1 1 0 PUCC protein Peptidase_M20 PF01546.23 EME86903.1 - 8.3e-19 67.8 0.1 1.2e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME86903.1 - 5.9e-13 48.5 0.1 1.2e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain His_Phos_2 PF00328.17 EME86903.1 - 0.05 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Dpoe2NT PF12213.3 EME86903.1 - 0.073 12.9 0.1 0.56 10.1 0.1 2.1 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal SIP1 PF04938.7 EME86904.1 - 8.2e-06 25.3 1.4 0.0011 18.4 0.6 3.0 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PV-1 PF06637.6 EME86905.1 - 0.055 12.0 0.1 0.12 10.9 0.1 1.5 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF869 PF05911.6 EME86905.1 - 0.55 8.4 3.5 0.8 7.8 2.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) PAT1 PF09770.4 EME86905.1 - 2.9 6.0 20.9 4 5.5 14.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BRI3BP PF14965.1 EME86906.1 - 1.1 8.5 2.7 25 4.2 0.1 2.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Osmo_CC PF08946.5 EME86906.1 - 3.7 7.6 18.2 0.18 11.8 0.7 4.2 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Tropomyosin_1 PF12718.2 EME86906.1 - 8.1 6.2 40.6 2.6 7.9 2.8 3.5 1 1 2 3 3 3 0 Tropomyosin like Spore_III_AB PF09548.5 EME86907.1 - 0.026 14.3 0.2 0.071 12.8 0.2 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MreB_Mbl PF06723.8 EME86907.1 - 0.036 12.6 0.3 4.4 5.8 0.0 2.8 2 1 0 2 2 2 0 MreB/Mbl protein AAA_13 PF13166.1 EME86907.1 - 6.3 5.1 16.9 0.13 10.7 2.8 2.6 2 1 1 3 3 3 0 AAA domain DUF3827 PF12877.2 EME86908.1 - 1.6 6.7 10.6 1.9 6.4 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4614 PF15391.1 EME86908.1 - 3.3 7.4 10.7 3.6 7.3 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CoA_transf_3 PF02515.12 EME86910.1 - 8.3e-42 142.5 0.0 1e-39 135.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III FMN_dh PF01070.13 EME86912.1 - 1.1e-103 346.8 0.3 1.6e-103 346.3 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EME86912.1 - 3e-19 68.5 0.0 6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThiG PF05690.9 EME86912.1 - 0.0096 15.0 1.3 0.22 10.5 0.0 2.4 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EME86912.1 - 0.021 13.7 0.2 0.046 12.6 0.0 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase IMPDH PF00478.20 EME86912.1 - 0.023 13.5 0.4 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain p450 PF00067.17 EME86913.1 - 5.3e-60 203.2 0.0 5.7e-48 163.5 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 Bunya_G1 PF03557.10 EME86913.1 - 0.26 9.0 0.0 0.35 8.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 DUF2385 PF09539.5 EME86914.1 - 0.76 10.1 5.0 2.1 8.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2385) DUF1910 PF08928.5 EME86914.1 - 1.1 9.2 6.2 13 5.7 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) MerR-DNA-bind PF09278.6 EME86914.1 - 5.9 7.3 10.7 18 5.7 0.3 3.9 3 0 0 3 3 3 0 MerR, DNA binding COG2 PF06148.6 EME86914.1 - 9.4 6.1 9.9 2.8 7.8 0.3 3.6 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Zn_clus PF00172.13 EME86915.1 - 5.1e-05 23.1 7.3 0.00011 22.0 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 EME86915.1 - 0.0049 16.5 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIC PF04977.10 EME86915.1 - 0.65 9.5 3.5 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator SAICAR_synt PF01259.13 EME86916.1 - 1.5e-88 296.1 0.0 1.8e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 EME86918.1 - 3.4e-30 103.7 3.0 3.4e-30 103.7 2.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 Exo_endo_phos_2 PF14529.1 EME86919.1 - 7.1e-15 54.6 0.0 1.8e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EME86919.1 - 1.4e-13 51.3 0.1 2.2e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EME86919.1 - 2.6e-05 24.0 0.5 6.2e-05 22.8 0.4 1.7 1 0 0 1 1 1 1 GRF zinc finger Nyv1_N PF09426.5 EME86919.1 - 0.053 13.0 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Na_trans_assoc PF06512.8 EME86919.1 - 0.14 12.1 2.8 0.2 11.5 1.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Somatostatin PF03002.10 EME86920.1 - 0.2 11.3 4.8 0.48 10.1 3.3 1.6 1 0 0 1 1 1 0 Somatostatin/Cortistatin family ATP-synt PF00231.14 EME86921.1 - 0.05 12.9 0.2 0.66 9.2 0.0 2.1 2 0 0 2 2 2 0 ATP synthase MAT_Alpha1 PF04769.7 EME86922.1 - 1.8e-30 105.7 0.0 2.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 DUF3328 PF11807.3 EME86923.1 - 5.8e-24 84.9 1.1 6.1e-24 84.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2404 PF10296.4 EME86924.1 - 1.7e-23 82.5 0.0 2.8e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ADH_zinc_N PF00107.21 EME86925.1 - 2.4e-23 82.0 0.0 6.6e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME86925.1 - 4.9e-21 74.5 0.3 9.1e-21 73.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Hydrolase_6 PF13344.1 EME86926.1 - 2.4e-24 85.1 0.0 5.4e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME86926.1 - 1.4e-18 66.3 0.0 3.3e-17 61.9 0.0 2.9 3 1 0 4 4 4 1 HAD-hyrolase-like HAD_2 PF13419.1 EME86926.1 - 4.3e-06 27.0 0.0 0.47 10.6 0.0 3.9 2 1 2 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME86926.1 - 3.9e-05 24.1 0.0 0.2 12.0 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase COX6A PF02046.10 EME86927.1 - 2.9e-45 152.9 1.3 3.4e-45 152.7 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa SCP2_2 PF13530.1 EME86927.1 - 0.023 14.0 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain F-box-like PF12937.2 EME86928.1 - 1.6e-08 34.1 1.1 3.6e-08 32.9 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME86928.1 - 0.003 17.1 0.7 0.019 14.6 0.0 2.6 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.2 EME86928.1 - 0.12 12.0 10.4 16 5.2 0.1 5.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EME86928.1 - 9.2 6.6 7.2 39 4.7 0.1 4.4 6 0 0 6 6 6 0 Leucine Rich repeat PALP PF00291.20 EME86929.1 - 1.1e-24 87.2 0.1 1.4e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF212 PF02681.9 EME86929.1 - 0.03 14.0 0.1 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Divergent PAP2 family PMT PF02366.13 EME86930.1 - 1.8e-80 269.8 17.6 3.2e-80 269.0 12.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EME86930.1 - 1e-53 181.6 0.1 1.7e-53 180.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 EME86932.1 - 1.8e-50 171.5 16.7 5.7e-50 169.9 11.6 1.8 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EME86932.1 - 1.5e-26 91.7 1.2 3.9e-13 48.8 0.1 2.7 2 0 0 2 2 2 2 Surp module DUF2688 PF10892.3 EME86932.1 - 0.13 11.9 0.0 5.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) TPX2 PF06886.6 EME86932.1 - 0.24 11.4 9.9 0.13 12.2 4.1 2.8 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DAO PF01266.19 EME86933.1 - 5.7e-06 25.4 0.0 1.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME86933.1 - 4.6e-05 23.3 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EME86933.1 - 0.0003 19.9 0.0 0.061 12.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EME86933.1 - 0.0047 16.7 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding ApbA_C PF08546.6 EME86935.1 - 2.2e-28 98.7 0.0 3.8e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME86935.1 - 3.4e-25 88.2 0.0 4.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EME86935.1 - 0.91 9.3 3.3 3 7.6 2.2 1.9 2 0 0 2 2 2 0 ThiF family PhyH PF05721.8 EME86936.1 - 1.7e-19 70.7 0.0 2.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_3 PF00202.16 EME86937.1 - 3.7e-38 131.2 0.0 4.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EME86937.1 - 6.1e-05 22.1 0.0 8.4e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CIA30 PF08547.7 EME86939.1 - 1.5e-40 138.6 0.0 2.5e-40 137.9 0.0 1.3 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EME86939.1 - 0.053 13.2 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Mito_carr PF00153.22 EME86940.1 - 6.4e-73 240.5 2.1 1.6e-24 85.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4567 PF15131.1 EME86940.1 - 0.044 13.9 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) Shisa PF13908.1 EME86941.1 - 2.2e-05 24.7 0.1 3.8e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3609 PF12259.3 EME86941.1 - 0.0006 18.5 0.4 0.0013 17.4 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3609) Adeno_E3_CR2 PF02439.10 EME86941.1 - 0.0011 18.4 0.9 0.0011 18.4 0.6 1.8 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EME86941.1 - 0.0017 16.7 0.0 0.0024 16.2 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EME86941.1 - 0.0017 17.2 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EME86941.1 - 0.0029 17.9 0.2 0.0056 17.0 0.1 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EME86941.1 - 0.009 15.6 0.3 0.012 15.2 0.2 1.3 1 0 0 1 1 1 1 Rifin/stevor family DAG1 PF05454.6 EME86941.1 - 0.012 14.7 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Plasmodium_Vir PF05795.6 EME86941.1 - 0.028 13.6 0.2 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein 7tm_1 PF00001.16 EME86941.1 - 0.042 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ctr PF04145.10 EME86941.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Ctr copper transporter family Glyco_hydro_72 PF03198.9 EME86942.1 - 5.8e-113 377.0 4.1 6.9e-113 376.7 2.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EME86942.1 - 6.6e-07 28.8 1.5 4.9e-06 25.9 1.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EME86942.1 - 0.0011 18.0 0.2 0.0018 17.2 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FAD_binding_3 PF01494.14 EME86943.1 - 2.4e-17 63.0 0.4 1e-16 60.9 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EME86943.1 - 6.8e-09 35.3 0.2 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EME86943.1 - 1.2e-06 27.7 0.5 0.00016 20.7 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME86943.1 - 4e-06 26.7 0.1 1.3e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME86943.1 - 0.0004 19.4 0.2 0.0053 15.7 0.2 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EME86943.1 - 0.0004 20.7 1.4 0.0023 18.3 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME86943.1 - 0.00073 18.2 0.3 0.014 14.0 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EME86943.1 - 0.0015 18.4 0.2 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME86943.1 - 0.0022 16.9 0.4 0.0041 16.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EME86943.1 - 0.037 14.0 0.3 0.18 11.8 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME86943.1 - 0.061 12.1 0.5 0.21 10.3 0.3 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EME86943.1 - 0.065 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EME86943.1 - 0.15 10.5 0.2 0.27 9.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Fructosamin_kin PF03881.9 EME86944.1 - 1.1e-73 247.7 0.0 1.3e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EME86944.1 - 0.0086 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EME86944.1 - 0.028 13.0 0.0 0.045 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ERG4_ERG24 PF01222.12 EME86945.1 - 2.5e-143 477.6 27.3 3e-143 477.4 18.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF946 PF06101.6 EME86946.1 - 2.8e-14 52.0 3.9 1.6e-13 49.5 2.7 1.9 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) Acetyltransf_10 PF13673.1 EME86947.1 - 9e-06 25.7 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME86947.1 - 0.0042 17.0 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME86947.1 - 0.0069 16.5 0.1 0.061 13.5 0.0 2.4 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 EME86948.1 - 2.4e-23 83.2 0.0 5.2e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME86948.1 - 1.4e-16 60.7 0.4 1.3e-15 57.6 0.3 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME86948.1 - 1.1e-08 34.9 0.0 5e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME86948.1 - 0.059 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase TPP_enzyme_N PF02776.13 EME86949.1 - 3e-36 124.4 0.2 5.7e-36 123.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME86949.1 - 7.2e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME86949.1 - 1.6e-15 57.1 0.0 3.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.15 EME86949.1 - 0.12 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF3636 PF12331.3 EME86950.1 - 7.5e-36 122.9 0.5 1.4e-35 122.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DivIC PF04977.10 EME86950.1 - 7.7 6.0 12.0 1.5 8.3 1.0 2.7 2 0 0 2 2 2 0 Septum formation initiator CTP_transf_1 PF01148.15 EME86951.1 - 6.1e-80 268.5 28.9 7.5e-80 268.3 20.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family AA_permease_C PF13906.1 EME86951.1 - 2.3 8.1 13.5 0.94 9.3 0.1 4.3 4 0 0 4 4 4 0 C-terminus of AA_permease Phosphorylase PF00343.15 EME86952.1 - 0 1086.0 0.3 0 1085.7 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase EIF_2_alpha PF07541.7 EME86953.1 - 1.2e-39 134.5 0.5 2.4e-39 133.5 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EME86953.1 - 4.1e-13 49.2 0.7 9.6e-13 48.0 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Stathmin PF00836.14 EME86953.1 - 0.2 11.2 3.1 0.21 11.2 0.4 2.0 2 0 0 2 2 2 0 Stathmin family MFS_1 PF07690.11 EME86956.1 - 2.7e-32 111.8 29.0 2.7e-32 111.8 20.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EME86956.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Mso1_Sec1_bdg PF14475.1 EME86957.1 - 4.1e-20 70.8 0.1 7.1e-20 70.1 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Acyl-CoA_dh_2 PF08028.6 EME86958.1 - 3.5e-18 66.1 2.4 1e-08 35.5 0.1 2.1 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 EME86958.1 - 7.3e-05 22.9 0.4 0.00054 20.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pyr_redox_3 PF13738.1 EME86960.1 - 1.9e-28 99.9 0.0 9.4e-28 97.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME86960.1 - 1.9e-07 31.1 0.0 0.00092 19.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EME86960.1 - 5.6e-07 28.8 0.0 1.9e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME86960.1 - 0.00051 19.8 0.0 0.031 14.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EME86960.1 - 0.15 12.1 0.0 0.85 9.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2OG-FeII_Oxy_3 PF13640.1 EME86961.1 - 0.0001 22.7 0.0 0.0012 19.2 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EME86961.1 - 0.0013 19.0 0.0 0.079 13.2 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NIPSNAP PF07978.8 EME86962.1 - 1.1e-38 131.2 6.8 6.5e-30 103.1 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP MFS_1 PF07690.11 EME86963.1 - 1.5e-43 148.9 30.3 1.5e-43 148.9 21.0 1.8 3 0 0 3 3 3 1 Major Facilitator Superfamily 4HBT PF03061.17 EME86964.1 - 1.2e-06 28.5 0.0 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily bZIP_1 PF00170.16 EME86965.1 - 2e-06 27.6 6.3 0.00012 21.9 2.6 2.6 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 EME86965.1 - 0.1 12.8 8.7 0.26 11.6 6.0 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EME86965.1 - 0.22 11.3 13.3 0.052 13.3 4.2 2.6 1 1 1 2 2 2 0 Basic region leucine zipper MIP PF00230.15 EME86968.1 - 2.1e-47 161.4 21.1 2.6e-47 161.1 14.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein zf-RING_2 PF13639.1 EME86969.1 - 9.7e-14 50.9 5.7 1.7e-13 50.1 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EME86969.1 - 3.6e-11 42.6 0.0 8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EME86969.1 - 1.1e-09 38.2 0.9 2.2e-09 37.3 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME86969.1 - 2e-09 37.3 5.2 3.3e-09 36.6 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME86969.1 - 9.7e-09 34.7 3.1 1.7e-08 33.9 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME86969.1 - 3.5e-08 32.9 3.3 5.4e-08 32.3 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME86969.1 - 2.5e-07 30.3 2.4 4.2e-07 29.5 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EME86969.1 - 0.00054 19.7 0.4 0.0011 18.7 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EME86969.1 - 0.087 12.8 3.7 0.18 11.8 2.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EME86969.1 - 0.091 12.6 4.0 0.2 11.5 2.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EME86969.1 - 0.1 12.3 2.6 0.24 11.1 1.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EME86969.1 - 0.12 12.3 2.3 0.33 10.9 1.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EME86969.1 - 0.91 9.1 2.5 1.7 8.2 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EME86969.1 - 1.7 8.7 3.4 3.1 7.8 2.4 1.5 1 0 0 1 1 1 0 RING-like domain LRR_4 PF12799.2 EME86970.1 - 2 8.1 7.3 1.4 8.6 0.1 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Rsm22 PF09243.5 EME86971.1 - 1.1e-28 100.0 0.0 3.5e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.20 EME86972.1 - 1.3e-38 132.6 0.0 1.6e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME86972.1 - 7.4e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME86972.1 - 1.5e-05 24.8 0.0 0.0015 18.2 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EME86972.1 - 0.05 12.3 0.1 0.075 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cupin_2 PF07883.6 EME86975.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain bZIP_1 PF00170.16 EME86976.1 - 7.4e-06 25.8 3.2 7.4e-06 25.8 2.2 2.3 2 1 1 3 3 3 1 bZIP transcription factor Cryptochrome_C PF12546.3 EME86976.1 - 0.00063 20.4 6.7 0.0023 18.6 3.4 2.2 1 1 1 2 2 2 1 Blue/Ultraviolet sensing protein C terminal ABC_tran_2 PF12848.2 EME86976.1 - 0.16 11.8 7.2 0.26 11.1 2.7 2.2 1 1 1 2 2 2 0 ABC transporter Git3 PF11710.3 EME86978.1 - 4.2e-19 68.9 11.3 2.5e-18 66.3 7.8 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EME86978.1 - 3.7e-06 26.5 0.0 1.4e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EME86978.1 - 0.078 12.0 12.1 0.1 11.6 8.4 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Bac_rhodopsin PF01036.13 EME86979.1 - 2.2e-61 207.0 16.4 2.7e-61 206.7 11.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.13 EME86979.1 - 0.015 14.8 4.0 0.015 14.8 2.8 1.8 2 1 1 3 3 3 0 Arterivirus GL envelope glycoprotein MARVEL PF01284.18 EME86979.1 - 0.14 11.9 16.0 0.038 13.8 1.1 2.8 2 1 1 3 3 3 0 Membrane-associating domain Intg_mem_TP0381 PF09529.5 EME86979.1 - 0.71 9.0 13.0 0.54 9.4 0.2 2.9 2 1 1 3 3 3 0 Integral membrane protein (intg_mem_TP0381) DUF4131 PF13567.1 EME86979.1 - 2.6 7.4 8.6 11 5.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.1 EME86979.1 - 4.1 6.4 7.4 9.9 5.2 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DAO PF01266.19 EME86980.1 - 3e-17 62.5 0.1 2.8e-08 33.0 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME86980.1 - 1.4e-12 47.4 0.1 1.6e-11 44.0 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME86980.1 - 3.1e-10 39.7 0.3 5.8e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EME86980.1 - 2.1e-07 30.1 0.7 1.6e-05 23.9 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EME86980.1 - 1.2e-05 25.3 0.0 3.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME86980.1 - 3.9e-05 22.2 0.0 0.0023 16.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EME86980.1 - 0.0002 20.5 0.2 0.00039 19.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EME86980.1 - 0.00072 18.7 0.5 0.0018 17.3 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EME86980.1 - 0.0013 17.8 0.5 0.0035 16.4 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME86980.1 - 0.0021 18.4 2.5 0.039 14.3 0.6 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME86980.1 - 0.0025 17.5 0.2 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME86980.1 - 0.0044 17.1 0.0 0.027 14.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME86980.1 - 0.0044 15.9 2.1 0.012 14.5 0.8 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A GDI PF00996.13 EME86980.1 - 0.017 13.4 0.1 1.3 7.2 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 EME86980.1 - 0.021 13.4 4.7 0.32 9.5 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 EME86980.1 - 0.032 14.4 0.2 0.084 13.1 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EME86980.1 - 0.04 13.5 0.4 0.077 12.6 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Strep_67kDa_ant PF06100.6 EME86980.1 - 0.1 10.9 0.0 1.3 7.3 0.1 2.0 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Lycopene_cycl PF05834.7 EME86980.1 - 0.14 11.0 0.7 0.24 10.3 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein PRC PF05239.11 EME86980.1 - 0.64 9.9 3.7 2.6 7.9 0.2 3.1 3 0 0 3 3 3 0 PRC-barrel domain SQS_PSY PF00494.14 EME86981.1 - 4e-65 219.7 0.0 5e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RPE65 PF03055.10 EME86982.1 - 1.8e-136 455.5 0.0 2.1e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 EME86982.1 - 0.079 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor PerB PF06590.6 EME86982.1 - 0.21 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 PerB protein Semialdhyde_dhC PF02774.13 EME86983.1 - 2.1e-40 138.5 0.0 2.7e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EME86983.1 - 1.5e-22 80.1 0.0 4.3e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EME86983.1 - 0.0034 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EME86983.1 - 0.0098 16.4 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 EME86983.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1996 PF09362.5 EME86984.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1996) End3 PF12761.2 EME86985.1 - 8.6e-68 227.8 1.3 1.3e-67 227.2 0.9 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EME86985.1 - 8.2e-49 163.6 0.2 4.7e-48 161.2 0.1 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EME86985.1 - 3.8e-08 32.0 0.4 1.2e-07 30.5 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EME86985.1 - 3.5e-07 29.7 0.1 7.6e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EME86985.1 - 1.6e-06 28.1 0.6 5.7e-06 26.3 0.1 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EME86985.1 - 9e-05 22.0 2.0 0.00047 19.8 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EME86985.1 - 0.00031 19.9 0.2 0.00082 18.6 0.1 1.7 1 0 0 1 1 1 1 EF hand DUF4140 PF13600.1 EME86985.1 - 0.45 10.9 4.6 13 6.2 0.3 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) AKNA PF12443.3 EME86985.1 - 0.67 10.0 2.8 3.7 7.6 0.3 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor FG-GAP PF01839.18 EME86985.1 - 1.5 8.6 4.4 3.1 7.6 3.0 1.5 1 0 0 1 1 1 0 FG-GAP repeat TPR_MLP1_2 PF07926.7 EME86985.1 - 1.9 8.2 8.9 33 4.2 5.7 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc97_Spc98 PF04130.8 EME86986.1 - 2.2e-37 128.5 0.3 8.3e-37 126.7 0.2 1.8 1 1 0 1 1 1 1 Spc97 / Spc98 family RAP1 PF07218.6 EME86987.1 - 3.7 5.5 9.5 3.9 5.4 6.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAD_binding_8 PF08022.7 EME86988.1 - 5.6e-16 58.3 0.0 1.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME86988.1 - 5.7e-15 55.5 0.0 9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME86988.1 - 8.1e-12 45.3 11.1 8.1e-12 45.3 7.7 2.7 3 1 0 3 3 3 1 Ferric reductase like transmembrane component Peptidase_S10 PF00450.17 EME86989.1 - 6e-85 285.8 3.3 8.1e-85 285.4 2.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF779 PF05610.6 EME86989.1 - 0.13 12.2 0.2 34 4.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF779) Zn_clus PF00172.13 EME86990.1 - 4.8e-05 23.1 8.4 9.2e-05 22.2 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME86991.1 - 3.9e-34 117.9 36.8 2.9e-33 115.0 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FmdA_AmdA PF03069.10 EME86993.1 - 7.9e-55 186.0 0.0 7.5e-29 100.5 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family LeuA_dimer PF08502.5 EME86993.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Ribosomal_L37e PF01907.14 EME86996.1 - 1.3e-25 88.8 11.2 1.9e-25 88.3 7.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EME86996.1 - 0.0016 18.1 0.9 0.0022 17.7 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EME86996.1 - 0.01 15.0 1.8 0.02 14.1 1.3 1.5 1 1 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 EME86996.1 - 0.071 12.7 0.7 0.096 12.3 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 EME86996.1 - 0.078 12.7 2.3 0.12 12.1 1.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-RING_5 PF14634.1 EME86996.1 - 0.36 10.5 4.0 0.54 10.0 2.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.1 EME86996.1 - 0.75 9.3 4.2 16 5.1 3.3 2.2 1 1 1 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EME86996.1 - 0.86 9.5 4.4 4.1 7.4 0.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.8 EME86996.1 - 1.4 8.4 6.3 3.1 7.3 0.9 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C3HC4_2 PF13923.1 EME86996.1 - 2 8.5 5.5 2.9 7.9 3.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME86996.1 - 3.6 7.3 6.0 5.6 6.7 4.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) INO80_Ies4 PF08193.6 EME86997.1 - 1.1e-07 32.0 1.2 1.1e-07 32.0 0.8 3.2 1 1 2 3 3 3 2 INO80 complex subunit Ies4 DUF2880 PF11082.3 EME86997.1 - 0.037 13.9 0.1 0.037 13.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Stm1_N PF09598.5 EME86999.1 - 0.11 13.2 6.0 0.31 11.7 4.2 1.9 1 0 0 1 1 1 0 Stm1 AA_permease_2 PF13520.1 EME87000.1 - 4.3e-52 177.0 45.1 5.4e-52 176.7 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME87000.1 - 1.6e-35 122.3 39.6 2.1e-35 121.9 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease PAN_1 PF00024.21 EME87001.1 - 0.17 11.6 0.1 0.17 11.6 0.1 1.6 2 0 0 2 2 2 0 PAN domain Serinc PF03348.10 EME87003.1 - 4.6e-140 467.1 10.7 6.1e-82 275.6 6.9 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) Git3 PF11710.3 EME87004.1 - 4.2e-15 55.8 18.5 1.4e-13 50.8 9.9 2.7 2 1 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EME87004.1 - 4.3e-06 26.3 1.7 6.5e-05 22.6 0.0 2.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EME87004.1 - 0.0005 19.0 8.9 0.00091 18.2 6.2 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor MFS_1 PF07690.11 EME87006.1 - 5.4e-36 124.0 30.1 8.3e-36 123.4 20.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily BAR_2 PF10455.4 EME87007.1 - 9.8e-57 192.0 0.5 1.4e-56 191.5 0.4 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EME87007.1 - 1.2e-15 57.6 5.7 2.5e-14 53.3 3.9 2.1 1 1 0 1 1 1 1 BAR domain DUF2564 PF10819.3 EME87007.1 - 0.16 12.0 7.0 0.075 13.1 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2564) CMD PF02627.15 EME87008.1 - 4.5e-18 64.8 0.0 9.2e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Lactamase_B PF00753.22 EME87009.1 - 5.1e-09 36.0 5.8 1.1e-08 34.9 4.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME87009.1 - 0.00018 21.1 3.7 0.00023 20.7 2.5 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Amidase PF01425.16 EME87010.1 - 3.9e-80 269.8 0.0 4.5e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Saccharop_dh_N PF04455.7 EME87011.1 - 0.11 12.5 0.9 0.27 11.3 0.6 1.6 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region PEP_mutase PF13714.1 EME87012.1 - 2.4e-43 148.0 2.7 2.9e-43 147.8 1.8 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EME87012.1 - 3.9e-18 64.9 0.3 5.8e-18 64.3 0.2 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Aconitase PF00330.15 EME87013.1 - 2.2e-56 191.2 2.9 1.4e-47 162.2 0.0 2.9 3 0 0 3 3 3 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EME87013.1 - 8.7e-12 45.2 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EME87013.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus DAO PF01266.19 EME87014.1 - 9.1e-54 182.7 0.0 1.1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME87014.1 - 1.6e-07 31.2 0.1 3.8e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME87014.1 - 8.9e-06 25.9 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EME87014.1 - 0.00054 19.9 0.2 0.00095 19.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 EME87014.1 - 0.0021 18.4 0.0 0.0061 16.9 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME87014.1 - 0.0065 16.3 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME87014.1 - 0.0067 15.3 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EME87014.1 - 0.0073 15.7 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EME87014.1 - 0.011 14.8 0.1 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EME87014.1 - 0.012 15.4 0.1 0.037 13.7 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME87014.1 - 0.023 13.6 0.2 0.045 12.6 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EME87014.1 - 0.031 12.7 0.2 0.042 12.3 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EME87014.1 - 0.042 12.9 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EME87014.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EME87014.1 - 0.13 11.9 0.3 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EME87014.1 - 0.16 11.1 0.1 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PH_4 PF15404.1 EME87016.1 - 1.4e-64 217.0 0.2 3e-64 215.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EME87016.1 - 4.2e-10 39.7 2.2 8.2e-05 22.7 0.1 4.4 3 2 0 3 3 3 2 PH domain PH_9 PF15410.1 EME87016.1 - 0.00095 19.3 0.0 2.9 8.0 0.0 4.0 4 0 0 4 4 4 1 Pleckstrin homology domain PH_6 PF15406.1 EME87016.1 - 0.0084 16.1 0.1 0.035 14.1 0.1 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EME87016.1 - 0.058 13.6 1.9 2.6 8.3 0.1 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain Mcp5_PH PF12814.2 EME87016.1 - 0.079 12.8 1.7 0.43 10.5 0.2 2.9 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Amino_oxidase PF01593.19 EME87020.1 - 1.1e-61 209.3 1.0 5.6e-61 206.9 0.7 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME87020.1 - 1.5e-14 53.7 0.2 2.9e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME87020.1 - 0.0025 17.8 0.1 0.013 15.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME87020.1 - 0.0053 15.6 0.0 0.048 12.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME87020.1 - 0.011 15.4 0.1 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EME87020.1 - 0.013 14.3 0.1 0.033 13.0 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EME87020.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EME87020.1 - 0.078 11.4 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TPP_enzyme_N PF02776.13 EME87021.1 - 3.3e-26 91.7 0.1 1.2e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME87021.1 - 3.6e-19 68.8 0.0 8.8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME87021.1 - 3.2e-18 65.7 0.0 5.1e-17 61.9 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Adaptin_N PF01602.15 EME87022.1 - 7.1e-116 387.5 1.5 9.2e-116 387.2 1.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EME87022.1 - 5.2e-56 188.6 0.2 1.3e-55 187.3 0.2 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EME87022.1 - 1.2e-15 57.5 4.5 1.8e-05 24.9 0.0 6.4 2 2 4 6 6 6 4 HEAT repeats HEAT_PBS PF03130.11 EME87022.1 - 0.021 15.2 1.3 11 6.8 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Sec7 PF01369.15 EME87022.1 - 0.022 14.4 0.2 2.7 7.6 0.0 3.0 2 1 0 2 2 2 0 Sec7 domain HEAT PF02985.17 EME87022.1 - 0.032 14.3 14.1 0.67 10.1 0.1 6.3 7 0 0 7 7 7 0 HEAT repeat F-actin_cap_A PF01267.12 EME87022.1 - 0.09 11.8 0.0 0.61 9.0 0.0 2.3 3 0 0 3 3 3 0 F-actin capping protein alpha subunit HEAT_EZ PF13513.1 EME87022.1 - 0.29 11.6 5.4 0.25 11.8 0.4 3.4 3 1 1 4 4 4 0 HEAT-like repeat Phosducin PF02114.11 EME87023.1 - 2.4e-10 39.5 0.2 3.4e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Phosducin DUF3337 PF11816.3 EME87025.1 - 0.017 14.5 4.3 0.023 14.1 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Ank_2 PF12796.2 EME87026.1 - 3.1e-28 97.9 0.0 1.6e-11 44.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EME87026.1 - 2.1e-24 84.0 0.1 4.8e-08 32.4 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EME87026.1 - 4e-18 65.4 0.7 0.00015 22.1 0.0 5.6 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME87026.1 - 1.1e-17 62.3 0.0 0.00039 20.3 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EME87026.1 - 2e-16 59.6 0.3 2.6e-07 30.6 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) WWbp PF10349.4 EME87026.1 - 0.037 14.9 0.0 0.065 14.1 0.0 1.4 1 0 0 1 1 1 0 WW-domain ligand protein bZIP_1 PF00170.16 EME87029.1 - 1.2e-07 31.6 11.9 2.5e-07 30.5 8.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EME87029.1 - 3.6e-07 30.2 9.1 2.6e-06 27.3 6.3 2.4 1 1 0 1 1 1 1 Transcription factor PAP1 Glutaredoxin2_C PF04399.8 EME87029.1 - 0.025 14.1 2.0 0.038 13.5 1.4 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 EME87029.1 - 0.026 14.8 9.5 0.041 14.1 6.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EME87029.1 - 0.073 12.9 12.4 0.13 12.0 7.7 2.0 1 1 1 2 2 2 0 Basic region leucine zipper LemA PF04011.7 EME87029.1 - 0.62 9.1 3.3 0.93 8.5 2.3 1.1 1 0 0 1 1 1 0 LemA family ADIP PF11559.3 EME87029.1 - 0.66 9.8 8.2 1.1 9.2 5.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Peptidase_C78 PF07910.8 EME87030.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C78 Methyltrn_RNA_3 PF02598.12 EME87031.1 - 1.8e-83 280.2 0.0 2e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EME87031.1 - 0.011 15.6 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family GFO_IDH_MocA PF01408.17 EME87032.1 - 8e-15 55.4 0.0 1.3e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Het-C PF07217.6 EME87032.1 - 0.00046 18.5 0.1 0.0011 17.3 0.0 1.5 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C NAD_binding_3 PF03447.11 EME87032.1 - 0.0086 16.4 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Grp1_Fun34_YaaH PF01184.14 EME87034.1 - 3.3e-26 91.9 22.9 3.8e-26 91.6 15.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DEAD PF00270.24 EME87037.1 - 6.7e-39 133.0 0.0 5.4e-38 130.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME87037.1 - 2.6e-20 72.0 0.1 6.2e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EME87037.1 - 0.0015 17.0 0.0 0.41 9.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) F-box-like PF12937.2 EME87038.1 - 4.3e-07 29.5 1.7 1e-06 28.3 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME87038.1 - 0.00018 21.1 0.6 0.0005 19.6 0.4 1.8 1 0 0 1 1 1 1 F-box domain Kelch_3 PF13415.1 EME87039.1 - 9.5e-36 121.1 11.5 1.5e-08 34.5 0.1 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EME87039.1 - 5.1e-35 119.0 12.6 2.7e-08 33.4 1.2 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EME87039.1 - 5.4e-31 106.0 7.8 2.2e-06 27.4 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EME87039.1 - 1e-26 91.9 8.7 2.6e-07 30.4 1.3 6.4 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EME87039.1 - 3.2e-26 90.5 2.2 2.4e-06 26.9 0.5 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EME87039.1 - 1.4e-17 62.6 4.1 0.0016 18.1 0.3 6.4 6 0 0 6 6 6 4 Kelch motif WEMBL PF05701.6 EME87039.1 - 3e-05 22.6 33.5 3e-05 22.6 23.3 3.2 2 1 0 2 2 2 1 Weak chloroplast movement under blue light ADIP PF11559.3 EME87039.1 - 0.0032 17.3 8.7 0.0032 17.3 6.0 8.2 3 2 6 10 10 10 3 Afadin- and alpha -actinin-Binding Strep_SA_rep PF06696.6 EME87039.1 - 0.12 12.1 14.4 17 5.3 0.0 6.4 6 0 0 6 6 6 0 Streptococcal surface antigen repeat Reo_sigmaC PF04582.7 EME87039.1 - 0.36 9.9 36.9 0.66 9.0 2.9 4.5 2 2 2 4 4 4 0 Reovirus sigma C capsid protein PAP2_3 PF14378.1 EME87041.1 - 1.1e-19 70.7 15.5 3.9e-17 62.4 3.7 2.4 3 0 0 3 3 3 2 PAP2 superfamily Sugar_tr PF00083.19 EME87042.1 - 2.8e-103 345.9 19.6 3.7e-103 345.5 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87042.1 - 1.1e-28 99.9 47.4 8.1e-27 93.8 17.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME87042.1 - 4.6e-06 25.2 19.8 0.00053 18.4 1.2 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein Peroxidase_2 PF01328.12 EME87044.1 - 5.3e-10 38.4 0.1 1.2e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 Peroxidase, family 2 Sugar_tr PF00083.19 EME87046.1 - 3.5e-94 315.9 24.4 4.3e-94 315.6 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87046.1 - 5.8e-19 68.0 37.6 4.4e-17 61.8 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.11 EME87047.1 - 1.8e-53 181.8 0.2 2.2e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WD40 PF00400.27 EME87048.1 - 8.2e-30 101.5 17.5 2.2e-07 30.5 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME87048.1 - 1.6e-05 23.3 0.7 0.01 14.1 0.0 3.8 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 EME87048.1 - 0.00011 22.3 1.4 0.31 11.3 0.0 3.3 4 0 0 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.6 EME87048.1 - 0.014 14.1 0.0 1.8 7.1 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 EME87048.1 - 0.028 14.0 0.1 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ATP-synt_J PF04911.7 EME87049.1 - 3.5e-26 90.4 3.4 3.8e-26 90.3 2.4 1.0 1 0 0 1 1 1 1 ATP synthase j chain DUF3433 PF11915.3 EME87050.1 - 2.4e-22 78.9 19.9 3.2e-14 52.8 1.7 4.4 3 1 0 3 3 3 2 Protein of unknown function (DUF3433) Spt20 PF12090.3 EME87051.1 - 4.6e-32 110.8 0.0 4.6e-32 110.8 0.0 5.1 3 2 0 3 3 3 1 Spt20 family Prok-JAB PF14464.1 EME87051.1 - 0.05 13.1 3.0 0.29 10.7 2.1 2.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DREPP PF05558.7 EME87051.1 - 0.28 10.9 10.6 2.9 7.6 6.3 2.5 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide Tubulin_3 PF14881.1 EME87052.1 - 7.8e-77 256.8 0.1 2e-76 255.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 EME87052.1 - 8e-38 129.0 0.0 1.6e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EME87052.1 - 0.00013 21.8 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF573 PF04504.9 EME87052.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF573 V_ATPase_I PF01496.14 EME87053.1 - 0.074 10.8 0.1 0.098 10.4 0.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Phosphoesterase PF04185.9 EME87057.1 - 1.2e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family FAM53 PF15242.1 EME87058.1 - 5.6 6.4 10.9 1.2 8.6 0.2 3.0 3 0 0 3 3 3 0 Family of FAM53 MUG113 PF13455.1 EME87061.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 PT PF04886.7 EME87061.1 - 1.5 8.1 13.6 0.17 11.2 1.4 2.5 2 0 0 2 2 2 0 PT repeat GMC_oxred_C PF05199.8 EME87062.1 - 4.5e-14 52.9 0.3 4.7e-14 52.8 0.2 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DUF4618 PF15397.1 EME87063.1 - 0.007 15.7 2.7 0.007 15.7 1.9 3.9 1 1 1 4 4 4 1 Domain of unknown function (DUF4618) MadM PF03818.8 EME87063.1 - 0.011 15.3 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit DUF2570 PF10828.3 EME87063.1 - 0.015 14.9 6.8 0.015 14.9 4.7 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF2570) ATG16 PF08614.6 EME87063.1 - 0.016 15.0 42.4 0.037 13.8 4.9 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Baculo_11_kDa PF06143.6 EME87063.1 - 0.066 12.5 0.6 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family GAS PF13851.1 EME87063.1 - 0.27 10.3 39.7 0.5 9.5 12.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 EME87063.1 - 1.1 9.3 25.2 0.61 10.2 3.7 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 EME87063.1 - 1.5 9.1 48.2 0.086 13.1 6.4 5.3 1 1 4 5 5 5 0 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 EME87063.1 - 1.9 8.3 50.1 0.51 10.1 3.2 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps51 PF08700.6 EME87063.1 - 2 8.3 18.4 20 5.1 7.7 4.4 1 1 3 4 4 4 0 Vps51/Vps67 MethyltransfD12 PF02086.10 EME87063.1 - 2 7.7 5.8 1.2 8.4 2.1 1.9 1 1 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF1515 PF07439.6 EME87063.1 - 5.1 6.9 7.7 19 5.0 2.1 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) bZIP_1 PF00170.16 EME87063.1 - 5.2 7.1 39.2 0.76 9.7 2.1 6.2 3 2 2 6 6 6 0 bZIP transcription factor FlaC_arch PF05377.6 EME87063.1 - 6.1 6.8 20.9 7.4 6.5 0.6 5.3 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) BBP1_C PF15272.1 EME87063.1 - 6.8 6.1 29.2 2.7 7.4 8.5 2.9 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal FH2 PF02181.18 EME87063.1 - 8.5 5.1 24.8 0.13 11.1 6.6 2.5 1 1 2 3 3 3 0 Formin Homology 2 Domain Carbpep_Y_N PF05388.6 EME87064.1 - 0.05 13.7 0.1 0.062 13.4 0.1 1.1 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide MFS_1 PF07690.11 EME87065.1 - 3.7e-06 25.8 7.8 3.7e-06 25.8 5.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_18 PF12847.2 EME87066.1 - 0.0032 18.0 0.0 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87066.1 - 0.034 13.7 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EME87066.1 - 0.09 13.1 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain HET PF06985.6 EME87067.1 - 2.1e-25 89.5 0.0 2.3e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UCH PF00443.24 EME87069.1 - 5.6e-49 166.6 0.0 8.6e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME87069.1 - 3.2e-18 66.1 0.0 8.7e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 EME87069.1 - 0.19 10.9 0.6 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Heme NO binding associated PX PF00787.19 EME87071.1 - 3.1e-24 84.9 0.1 3.7e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 PX domain EXOSC1 PF10447.4 EME87073.1 - 0.13 12.1 0.0 19 5.2 0.0 2.3 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 HSP70 PF00012.15 EME87074.1 - 7.5e-75 252.0 3.5 1.1e-74 251.4 2.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME87074.1 - 2.6e-08 32.8 0.4 5e-08 31.9 0.3 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EME87074.1 - 0.001 18.0 0.2 0.29 9.9 0.0 2.4 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; LtrA PF06772.6 EME87076.1 - 0.0014 17.6 3.4 0.002 17.1 2.4 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) VSP PF03302.8 EME87077.1 - 3.1e-05 22.7 0.8 4.7e-05 22.1 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Asp PF00026.18 EME87077.1 - 0.0011 18.3 0.2 0.0029 16.8 0.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease IFP_35_N PF07334.8 EME87077.1 - 0.018 15.0 0.0 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1049 PF06305.6 EME87077.1 - 0.023 14.1 0.6 0.045 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2681 PF10883.3 EME87077.1 - 0.2 11.9 0.2 0.33 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Zn_clus PF00172.13 EME87079.1 - 0.0081 16.0 1.2 0.02 14.7 0.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.4 EME87080.1 - 1.6e-09 38.0 0.2 1.6e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rax2 PF12768.2 EME87080.1 - 0.0058 15.8 0.0 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 Cortical protein marker for cell polarity PgaD PF13994.1 EME87080.1 - 0.012 15.0 0.4 0.037 13.5 0.0 1.9 2 0 0 2 2 2 0 PgaD-like protein FixQ PF05545.6 EME87080.1 - 0.041 13.5 0.9 0.062 12.9 0.0 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ YajC PF02699.10 EME87080.1 - 0.046 13.3 0.0 10 5.8 0.0 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit SKG6 PF08693.5 EME87080.1 - 0.12 11.6 0.1 0.29 10.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ApbA_C PF08546.6 EME87081.1 - 3e-29 101.5 0.1 6.3e-29 100.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EME87081.1 - 1.5e-17 63.4 0.0 5.5e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA RdRP PF05183.7 EME87083.1 - 2.9e-173 577.6 0.0 4.5e-173 577.0 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase EHN PF06441.7 EME87084.1 - 5.5e-37 126.1 1.7 4.5e-36 123.1 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EME87084.1 - 1.5e-11 44.3 0.1 2.6e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME87084.1 - 3.1e-10 40.3 0.2 5.4e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Coq4 PF05019.8 EME87086.1 - 3.4e-98 326.9 0.0 4.2e-98 326.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 NAD_binding_10 PF13460.1 EME87087.1 - 5.6e-14 52.5 0.1 9.3e-14 51.8 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EME87087.1 - 1.7e-10 40.7 0.0 2.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME87087.1 - 1.6e-06 27.5 0.1 2.5e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EME87087.1 - 4.4e-06 26.6 0.0 6.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 EME87087.1 - 1.3e-05 24.2 0.1 2.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EME87087.1 - 1.5e-05 24.1 0.1 1.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EME87087.1 - 3.1e-05 24.2 0.0 5.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EME87087.1 - 0.0011 18.8 0.9 0.0019 18.1 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EME87087.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.18 EME87087.1 - 0.016 15.0 0.1 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 EME87087.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain DapB_N PF01113.15 EME87087.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EME87087.1 - 0.073 13.6 1.2 9.4 6.7 0.1 2.3 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 EME87087.1 - 0.13 11.1 0.0 0.29 9.9 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Marek_A PF02124.10 EME87088.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Marek's disease glycoprotein A ANTH PF07651.11 EME87089.1 - 6.2e-78 261.3 4.2 1.2e-76 257.0 0.0 3.5 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EME87089.1 - 1.4e-63 213.3 7.2 1.4e-63 213.3 5.0 5.9 6 0 0 6 6 6 2 I/LWEQ domain ENTH PF01417.15 EME87089.1 - 0.00045 20.0 0.0 0.0032 17.3 0.0 2.5 1 0 0 1 1 1 1 ENTH domain TcdB_N PF12918.2 EME87089.1 - 0.0015 18.5 1.1 0.0015 18.5 0.8 4.0 5 0 0 5 5 5 1 TcdB toxin N-terminal helical domain APH PF01636.18 EME87090.1 - 6.8e-13 48.9 0.0 1.4e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S4e PF00900.15 EME87091.1 - 1.9e-32 110.7 0.4 3.7e-32 109.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EME87091.1 - 9.7e-18 63.7 4.4 1.8e-17 62.9 3.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EME87091.1 - 2.3e-09 36.5 0.1 4.8e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EME87091.1 - 0.0028 17.3 0.6 0.0028 17.3 0.4 2.9 3 0 0 3 3 3 1 KOW motif DUF3176 PF11374.3 EME87094.1 - 4.4e-27 94.1 1.7 4.4e-27 94.1 1.2 2.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3176) DUF4199 PF13858.1 EME87095.1 - 0.0012 18.7 0.3 0.004 17.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) TPR_11 PF13414.1 EME87096.1 - 1.7e-15 56.4 4.4 3.9e-09 36.0 0.3 4.7 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EME87096.1 - 3.7e-07 29.4 1.1 0.00036 20.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EME87096.1 - 5.8e-07 29.2 0.5 0.022 14.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME87096.1 - 5e-05 22.9 9.2 0.00029 20.5 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME87096.1 - 0.00055 20.3 0.3 0.00055 20.3 0.2 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME87096.1 - 0.00084 19.9 4.9 0.015 15.9 0.1 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME87096.1 - 0.0017 18.0 0.3 0.039 13.7 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME87096.1 - 0.072 12.9 3.0 0.13 12.1 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME87096.1 - 1 9.3 9.8 0.79 9.7 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME87096.1 - 1.3 8.9 4.7 11 6.0 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Med21 PF11221.3 EME87098.1 - 2.6e-39 134.4 2.0 3e-39 134.2 1.4 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 EME87098.1 - 9.2e-05 22.2 0.7 9.2e-05 22.2 0.5 1.4 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) KIX PF02172.11 EME87098.1 - 0.00051 20.0 0.7 0.00088 19.2 0.2 1.6 2 0 0 2 2 2 1 KIX domain Med9 PF07544.8 EME87098.1 - 0.00059 19.5 1.5 0.00059 19.5 1.1 2.7 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Nexin_C PF08628.7 EME87098.1 - 0.032 14.3 0.7 0.054 13.5 0.5 1.4 1 0 0 1 1 1 0 Sorting nexin C terminal AAA_13 PF13166.1 EME87098.1 - 0.033 12.6 0.3 0.036 12.5 0.2 1.1 1 0 0 1 1 1 0 AAA domain Troponin PF00992.15 EME87098.1 - 0.078 13.0 5.1 0.12 12.4 3.5 1.3 1 0 0 1 1 1 0 Troponin AHSP PF09236.5 EME87098.1 - 0.3 11.3 1.4 1.2 9.4 1.0 1.9 1 1 0 1 1 1 0 Alpha-haemoglobin stabilising protein DUF1192 PF06698.6 EME87098.1 - 5.9 6.7 7.0 18 5.1 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF2034 PF10356.4 EME87099.1 - 2.8e-21 75.5 0.0 1.3e-11 43.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EME87099.1 - 0.00048 19.9 0.0 0.00073 19.3 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease Aminotran_5 PF00266.14 EME87100.1 - 2.1e-22 79.4 0.0 3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EME87100.1 - 7.2e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EME87100.1 - 0.001 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 EME87101.1 - 1.4e-29 103.0 0.0 8e-17 61.2 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME87101.1 - 1.9e-13 50.0 0.0 2.3e-07 30.1 0.0 4.1 2 2 0 2 2 2 2 Protein tyrosine kinase EcKinase PF02958.15 EME87101.1 - 0.49 9.4 0.0 1.3 8.0 0.0 1.6 1 0 0 1 1 1 0 Ecdysteroid kinase Leuk-A4-hydro_C PF09127.6 EME87102.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Acetyltransf_1 PF00583.19 EME87105.1 - 3.6e-11 42.9 0.2 6.5e-11 42.1 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME87105.1 - 7.6e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME87105.1 - 0.00092 18.9 0.0 0.033 13.9 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EME87105.1 - 0.0019 18.3 0.0 0.015 15.4 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME87105.1 - 0.0084 15.9 0.0 0.087 12.6 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME87105.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Xan_ur_permease PF00860.15 EME87106.1 - 3.9e-08 32.1 0.4 6.3e-08 31.5 0.2 1.2 1 0 0 1 1 1 1 Permease family Fungal_trans PF04082.13 EME87106.1 - 0.0022 16.9 0.0 0.0057 15.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 EME87107.1 - 2.4e-26 92.1 22.6 1.1e-16 60.1 6.8 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME87107.1 - 1.2e-12 47.1 44.8 1.2e-12 47.1 31.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 EME87109.1 - 5.1e-08 32.6 7.2 5.1e-08 32.6 5.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EME87109.1 - 0.0001 22.3 4.7 0.0001 22.3 3.3 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EME87109.1 - 0.00089 19.0 2.1 0.00089 19.0 1.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.12 EME87109.1 - 0.0011 18.3 0.4 0.0024 17.3 0.3 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_5 PF14634.1 EME87109.1 - 0.0049 16.5 10.1 0.0049 16.5 7.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EME87109.1 - 0.0093 15.5 10.1 0.0093 15.5 7.0 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EME87109.1 - 0.16 11.9 13.4 0.059 13.3 6.8 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EME87109.1 - 0.41 10.7 8.9 0.87 9.6 6.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EME87109.1 - 0.52 10.3 12.0 0.14 12.1 5.9 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME87109.1 - 1.8 8.3 11.8 0.41 10.3 5.7 1.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Trehalase PF01204.13 EME87110.1 - 0.00028 19.6 0.0 0.00042 19.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase DUF3328 PF11807.3 EME87111.1 - 2.5e-30 105.8 2.0 2.8e-30 105.6 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_tranf_2_3 PF13641.1 EME87114.1 - 2.2e-32 112.7 0.0 3.4e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EME87114.1 - 3e-21 76.0 0.8 3e-21 76.0 0.5 2.8 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EME87114.1 - 5.9e-21 74.8 0.0 8.4e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EME87114.1 - 3.6e-17 62.1 0.0 5.8e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EME87114.1 - 0.00084 17.7 5.4 0.12 10.7 1.5 2.2 2 0 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 EME87114.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_12 PF01670.11 EME87115.1 - 1.3e-13 51.0 0.6 3e-13 49.8 0.5 1.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 EI24 PF07264.6 EME87116.1 - 4.3e-08 32.8 9.4 2.2e-07 30.5 6.5 2.0 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LAP1C PF05609.7 EME87117.1 - 2.4 6.7 10.4 3.4 6.2 7.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) p450 PF00067.17 EME87118.1 - 1.2e-43 149.2 0.1 1.6e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 EME87119.1 - 7e-14 51.6 0.0 2e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME87119.1 - 8.5e-09 35.6 0.0 1.3e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME87119.1 - 0.00024 20.6 0.1 0.0022 17.4 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EME87119.1 - 0.004 17.0 0.1 0.0069 16.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EME87119.1 - 0.007 15.2 0.1 0.27 10.0 0.1 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 EME87119.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.5 EME87119.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 KR domain TauD PF02668.11 EME87120.1 - 1.3e-26 93.8 0.1 1.8e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Bunya_nucleocap PF00952.12 EME87120.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein PRAP PF15314.1 EME87120.1 - 0.39 11.0 0.1 0.39 11.0 0.0 2.5 3 0 0 3 3 3 0 Proline-rich acidic protein 1, pregnancy-specific uterine polyprenyl_synt PF00348.12 EME87121.1 - 4.5e-36 124.0 0.0 7.8e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EME87121.1 - 1.1e-07 31.3 0.0 3.6e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain ANTAR PF03861.9 EME87121.1 - 0.00092 18.7 0.1 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 ANTAR domain LdpA_C PF12617.3 EME87122.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal p450 PF00067.17 EME87123.1 - 1.5e-55 188.6 0.0 1.8e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3915 PF13054.1 EME87123.1 - 0.038 13.9 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Methyltransf_2 PF00891.13 EME87124.1 - 4.9e-18 65.2 0.0 8.1e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase p450 PF00067.17 EME87125.1 - 1.3e-35 122.8 0.0 1.8e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DBR1 PF05011.8 EME87125.1 - 0.028 14.3 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain p450 PF00067.17 EME87126.1 - 2.3e-53 181.3 0.0 3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3662 PF12401.3 EME87126.1 - 0.021 14.9 0.0 0.064 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) DUF4063 PF13272.1 EME87126.1 - 0.11 12.3 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) Transglut_core PF01841.14 EME87127.1 - 1.1e-12 48.1 0.0 3.7e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EME87127.1 - 0.0024 17.1 0.0 0.036 13.3 0.0 2.2 2 1 0 2 2 2 1 Transglutaminase-like domain SGL PF08450.7 EME87128.1 - 8.8e-59 198.8 0.0 1.1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EME87128.1 - 0.096 12.6 0.0 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 NHL repeat DUF839 PF05787.8 EME87128.1 - 0.13 11.1 0.0 0.55 9.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF839) Pkinase PF00069.20 EME87129.1 - 4.6e-53 180.0 0.0 7.3e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87129.1 - 8.5e-14 51.2 0.0 2.6e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EME87129.1 - 0.3 9.8 0.1 0.44 9.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SCIMP PF15050.1 EME87129.1 - 4.2 7.2 5.9 1.4 8.8 1.6 2.0 1 1 1 2 2 2 0 SCIMP protein Choline_kinase PF01633.15 EME87130.1 - 2.1e-59 200.6 0.0 3.8e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EME87130.1 - 1.9e-17 62.4 0.1 7.2e-17 60.5 0.0 2.0 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 EME87130.1 - 8.4e-08 32.2 0.6 2.4e-07 30.7 0.4 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.22 EME87131.1 - 7.6e-49 166.2 0.4 3.6e-48 164.0 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EME87131.1 - 4e-31 107.8 0.5 2e-30 105.6 0.1 2.5 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EME87131.1 - 1.4e-10 40.3 0.0 3.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain B12-binding_2 PF02607.12 EME87131.1 - 0.065 13.2 0.8 36 4.4 0.0 4.0 3 0 0 3 3 3 0 B12 binding domain Asp PF00026.18 EME87132.1 - 1.4e-78 264.3 7.3 1.9e-78 263.9 5.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EME87132.1 - 3e-09 37.0 1.0 3e-09 37.0 0.7 2.4 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EME87132.1 - 2.4e-06 27.9 0.1 0.021 15.3 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EME87132.1 - 0.0037 16.8 0.0 0.062 12.8 0.0 2.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal UDPG_MGDP_dh_N PF03721.9 EME87133.1 - 2.4e-48 164.0 0.0 4.4e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EME87133.1 - 2.4e-31 107.8 0.0 4.8e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EME87133.1 - 2e-22 79.3 0.0 4.4e-19 68.5 0.0 3.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Saccharop_dh PF03435.13 EME87133.1 - 0.00052 19.1 0.0 0.00099 18.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EME87133.1 - 0.0019 17.9 0.1 0.04 13.6 0.0 2.8 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EME87133.1 - 0.032 13.6 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EME87133.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EME87133.1 - 0.098 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ABC_tran PF00005.22 EME87134.1 - 1.6e-50 170.9 0.2 1.3e-25 90.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EME87134.1 - 7e-24 84.4 51.5 1.7e-12 47.0 11.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EME87134.1 - 4.2e-20 72.8 0.0 0.00026 21.0 0.0 4.3 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EME87134.1 - 3.3e-11 42.8 1.0 0.00092 18.5 0.0 4.4 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME87134.1 - 1.1e-08 34.5 2.1 0.00076 18.9 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EME87134.1 - 7.8e-06 26.3 4.1 0.0065 16.8 0.1 2.6 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EME87134.1 - 5.7e-05 22.3 0.1 0.051 12.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME87134.1 - 0.00091 19.2 2.3 0.84 9.5 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain ABC2_membrane_4 PF12730.2 EME87134.1 - 0.002 17.3 10.9 0.002 17.3 7.6 3.5 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EME87134.1 - 0.0055 16.1 0.3 0.47 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EME87134.1 - 0.01 15.2 0.2 1.7 8.0 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EME87134.1 - 0.012 15.5 0.3 9.3 6.2 0.0 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 EME87134.1 - 0.017 13.8 0.0 0.059 12.0 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 EME87134.1 - 0.019 15.0 1.0 0.65 10.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME87134.1 - 0.025 14.5 0.4 1.7 8.5 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EME87134.1 - 0.032 14.1 1.8 3.1 7.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain Miro PF08477.8 EME87134.1 - 0.046 14.2 0.1 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EME87134.1 - 0.084 11.9 0.0 5 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain DUF4162 PF13732.1 EME87134.1 - 0.18 12.3 0.1 0.54 10.8 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4162) AAA_10 PF12846.2 EME87134.1 - 0.2 11.0 0.9 17 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FRG2 PF15315.1 EME87134.1 - 0.46 10.4 1.5 1.3 8.9 1.0 1.7 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 AAA_19 PF13245.1 EME87134.1 - 2.1 8.1 6.0 12 5.6 0.1 3.6 3 0 0 3 3 3 0 Part of AAA domain Glyco_hydro_63 PF03200.11 EME87135.1 - 1.8e-232 773.5 0.2 1.9e-231 770.2 0.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EME87135.1 - 1.3e-06 27.3 0.8 2.3e-06 26.5 0.6 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EME87135.1 - 0.00015 20.6 0.2 0.00026 19.8 0.2 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 EME87135.1 - 0.022 12.9 0.0 0.046 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Glyco_hydro_3 PF00933.16 EME87136.1 - 6.5e-46 156.6 0.0 8.4e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME87136.1 - 1.2e-13 51.0 0.1 2.9e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain FAD_binding_3 PF01494.14 EME87138.1 - 4.5e-17 62.1 0.5 5.2e-11 42.1 0.8 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME87138.1 - 1.6e-11 43.7 0.2 1.7e-07 30.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME87138.1 - 1.1e-08 35.0 0.4 3.3e-08 33.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EME87138.1 - 1.2e-07 32.0 0.3 2e-06 28.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME87138.1 - 1.5e-06 27.1 2.7 0.007 15.0 0.4 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EME87138.1 - 1.7e-06 28.0 0.2 3.1e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME87138.1 - 2.2e-06 26.8 0.3 4e-06 25.9 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EME87138.1 - 0.00019 20.0 0.2 0.0003 19.3 0.2 1.5 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EME87138.1 - 0.0015 17.6 0.3 0.0086 15.1 0.1 2.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EME87138.1 - 0.0016 18.5 0.4 0.0039 17.2 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME87138.1 - 0.0017 17.4 0.1 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EME87138.1 - 0.0021 17.0 0.3 0.0048 15.8 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 EME87138.1 - 0.0032 16.9 0.1 0.0097 15.3 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EME87138.1 - 0.01 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EME87138.1 - 0.018 14.7 0.2 0.084 12.6 0.2 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EME87138.1 - 0.026 14.1 0.1 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EME87138.1 - 0.035 12.9 0.2 0.048 12.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EME87138.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EME87138.1 - 0.082 11.9 1.3 0.11 11.5 0.9 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EME87138.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GCV_T PF01571.16 EME87140.1 - 1.8e-59 200.6 0.0 2.5e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EME87140.1 - 8.7e-23 80.1 0.5 1.6e-22 79.2 0.4 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 EME87140.1 - 0.00043 20.2 0.0 0.023 14.6 0.0 3.2 4 0 0 4 4 4 1 GTP-binding protein TrmE N-terminus V-ATPase_C PF03223.10 EME87141.1 - 2.2e-113 378.9 0.0 2.5e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Trp_syntA PF00290.15 EME87143.1 - 2.4e-88 295.0 0.0 4.6e-88 294.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EME87143.1 - 6.7e-45 153.6 1.3 1e-44 153.0 0.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ComA PF02679.10 EME87143.1 - 0.15 11.0 0.0 0.32 9.9 0.0 1.5 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) RabGAP-TBC PF00566.13 EME87145.1 - 3.1e-46 157.5 0.1 9.6e-45 152.6 0.0 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 EME87145.1 - 0.049 13.4 17.2 0.18 11.6 3.2 3.2 3 0 0 3 3 3 0 Microtubule associated DUF972 PF06156.8 EME87145.1 - 0.24 11.7 24.7 0.047 14.0 4.9 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF972) HALZ PF02183.13 EME87145.1 - 5.3 6.8 13.7 0.98 9.1 0.4 3.9 2 1 0 3 3 3 0 Homeobox associated leucine zipper RPN7 PF10602.4 EME87146.1 - 7.9e-56 188.2 0.5 1.3e-55 187.4 0.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EME87146.1 - 2.2e-13 50.4 0.0 5.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 EME87146.1 - 0.02 15.4 0.0 0.09 13.4 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EME87146.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME87146.1 - 0.049 13.5 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME87146.1 - 0.053 13.3 0.1 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_tran_2 PF12848.2 EME87146.1 - 3.2 7.6 7.2 27 4.6 0.0 3.0 2 0 0 2 2 2 0 ABC transporter Pox_MCEL PF03291.11 EME87147.1 - 4.1e-65 219.8 0.0 3.6e-43 147.7 0.0 2.7 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EME87147.1 - 2.6e-08 34.2 0.0 9e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87147.1 - 7.3e-06 25.6 0.0 8.2e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME87147.1 - 8.6e-06 26.1 0.0 0.00038 20.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME87147.1 - 2e-05 24.3 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME87147.1 - 6.7e-05 23.1 0.0 0.00014 22.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87147.1 - 0.00037 21.0 0.0 0.00088 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME87147.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain EBP50_C-term PF09007.6 EME87147.1 - 0.026 14.3 2.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 EBP50, C-terminal NNMT_PNMT_TEMT PF01234.12 EME87147.1 - 0.038 12.9 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Raftlin PF15250.1 EME87147.1 - 0.088 11.3 0.7 0.14 10.6 0.0 1.6 2 0 0 2 2 2 0 Raftlin PLA2_B PF01735.13 EME87150.1 - 8.2e-177 588.2 0.9 1e-176 587.9 0.6 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PNP_UDP_1 PF01048.15 EME87152.1 - 3.8e-39 134.0 0.0 4.6e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.20 EME87153.1 - 3.1e-43 147.8 0.0 1.5e-42 145.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87153.1 - 5.8e-29 100.9 0.0 8.3e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME87153.1 - 6.7e-06 25.2 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME87153.1 - 0.041 12.9 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPT2 PF08243.6 EME87154.1 - 3e-05 24.3 19.9 4e-05 23.9 12.8 1.8 1 1 1 2 2 2 1 SPT2 chromatin protein TFIIA PF03153.8 EME87154.1 - 5.9 6.6 16.1 8 6.2 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 EME87155.1 - 3.9e-27 94.4 11.8 5e-27 94.1 8.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 EME87155.1 - 0.13 10.4 0.9 0.14 10.2 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) S1 PF00575.18 EME87156.1 - 1e-08 35.1 0.9 1.5e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 EME87156.1 - 0.00019 21.5 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EME87156.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 AA_permease_2 PF13520.1 EME87159.1 - 5e-48 163.6 35.7 6.5e-48 163.3 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME87159.1 - 1.8e-23 82.6 31.3 2.4e-23 82.2 21.7 1.1 1 0 0 1 1 1 1 Amino acid permease DDE_Tnp_4 PF13359.1 EME87160.1 - 1.1e-08 34.8 0.3 1.2e-08 34.7 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 EME87160.1 - 0.00015 21.9 0.2 0.00016 21.7 0.2 1.0 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 EME87160.1 - 0.00089 18.6 0.0 0.00089 18.6 0.0 1.0 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 EME87160.1 - 0.0048 16.4 0.0 0.0048 16.4 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain Pectate_lyase_3 PF12708.2 EME87161.1 - 2.3e-58 198.0 17.4 3.4e-41 141.8 5.1 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EME87161.1 - 4.4e-06 26.0 2.1 0.017 14.5 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RRM_1 PF00076.17 EME87164.1 - 5.6e-17 61.1 0.0 9.3e-13 47.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME87164.1 - 4.6e-13 48.7 0.0 6.4e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME87164.1 - 1.2e-12 47.5 0.0 3.3e-09 36.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Viral_Rep PF02407.11 EME87164.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative viral replication protein Sds3 PF08598.6 EME87165.1 - 9e-19 67.8 13.2 2.7e-18 66.2 4.8 3.1 2 1 0 2 2 2 2 Sds3-like PMT PF02366.13 EME87166.1 - 4.8e-80 268.4 18.2 4.8e-80 268.4 12.6 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EME87166.1 - 6.9e-20 71.3 0.3 2.3e-19 69.6 0.1 1.8 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EME87166.1 - 2.5e-07 30.7 13.3 2.5e-07 30.7 9.2 3.5 4 1 1 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Methyltransf_11 PF08241.7 EME87167.1 - 2.6e-18 66.2 0.0 2.1e-17 63.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87167.1 - 1.2e-14 54.1 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME87167.1 - 3.6e-14 52.7 0.0 5.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME87167.1 - 4.2e-13 49.5 0.0 1.2e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME87167.1 - 1.3e-09 38.2 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87167.1 - 3.1e-08 34.1 0.0 7.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME87167.1 - 5.9e-08 32.1 0.0 1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME87167.1 - 2.1e-07 30.9 0.0 5.9e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME87167.1 - 1.3e-06 27.7 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EME87167.1 - 2.1e-06 27.2 0.0 3.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EME87167.1 - 0.00011 21.2 0.0 0.00023 20.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.9 EME87167.1 - 0.00063 18.9 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 EME87167.1 - 0.0012 18.0 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EME87167.1 - 0.0019 17.2 0.0 0.005 15.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EME87167.1 - 0.0044 16.5 0.0 0.02 14.4 0.0 1.9 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 EME87167.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) GCD14 PF08704.5 EME87167.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_2 PF00891.13 EME87167.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_17 PF12692.2 EME87167.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Methyltransf_8 PF05148.10 EME87167.1 - 0.12 11.9 0.0 2.6 7.6 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase Pkinase PF00069.20 EME87168.1 - 3.3e-18 65.7 0.0 7e-18 64.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87168.1 - 2.1e-09 36.8 0.0 9.7e-09 34.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3425 PF11905.3 EME87169.1 - 3.8e-17 62.4 0.7 1.2e-16 60.8 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Aminotran_4 PF01063.14 EME87170.1 - 3.8e-24 85.4 0.0 5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Prominin PF05478.6 EME87172.1 - 0.11 9.9 0.5 0.15 9.5 0.3 1.1 1 0 0 1 1 1 0 Prominin tRNA_m1G_MT PF01746.16 EME87172.1 - 0.93 9.0 9.5 1.5 8.3 0.2 3.2 2 1 1 3 3 3 0 tRNA (Guanine-1)-methyltransferase Herpes_UL25 PF01499.11 EME87172.1 - 2.3 6.4 6.8 3.1 6.0 4.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Methyltransf_23 PF13489.1 EME87174.1 - 3e-10 40.0 0.0 7.8e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87174.1 - 3.3e-05 24.4 0.0 0.00016 22.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87174.1 - 0.00018 21.1 0.0 0.0013 18.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_16 PF10294.4 EME87174.1 - 0.00087 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EME87174.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EME87174.1 - 0.014 14.4 0.0 5.9 5.9 0.0 2.6 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EME87174.1 - 0.031 14.7 0.1 0.54 10.7 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EME87174.1 - 0.036 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EME87174.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EME87174.1 - 0.047 14.1 0.0 0.3 11.5 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_2 PF00891.13 EME87174.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EME87174.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3818 PF12825.2 EME87176.1 - 2.2e-132 440.8 3.8 3.4e-132 440.2 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EME87176.1 - 2.6e-42 143.6 4.7 9.5e-41 138.6 0.5 2.5 2 0 0 2 2 2 2 PX-associated PX PF00787.19 EME87176.1 - 5.2e-12 45.5 0.1 4.9e-11 42.4 0.0 2.7 1 1 0 1 1 1 1 PX domain F-box PF00646.28 EME87177.1 - 0.073 12.7 0.8 0.31 10.7 0.1 2.4 3 0 0 3 3 3 0 F-box domain PIN PF01850.16 EME87177.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 PIN domain DPPIV_N PF00930.16 EME87178.1 - 3e-98 328.6 0.3 3.9e-98 328.2 0.2 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EME87178.1 - 8.1e-53 178.8 6.8 8.1e-53 178.8 4.7 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME87178.1 - 2.1e-10 40.5 0.2 4.7e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EME87178.1 - 5e-07 29.4 5.0 0.00013 21.4 0.9 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EME87178.1 - 5.1e-07 29.7 0.1 2.9e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EME87178.1 - 0.00011 21.6 0.1 0.00028 20.3 0.1 1.7 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 EME87178.1 - 0.001 18.4 0.2 0.0076 15.5 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EME87178.1 - 0.009 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Inh PF02974.9 EME87178.1 - 0.066 12.7 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Protease inhibitor Inh Abhydrolase_2 PF02230.11 EME87178.1 - 0.079 12.3 0.1 6.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PD40 PF07676.7 EME87178.1 - 0.11 12.1 1.0 6.7 6.4 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LSM PF01423.17 EME87180.1 - 5.3e-14 51.5 0.6 1e-13 50.5 0.4 1.5 1 0 0 1 1 1 1 LSM domain Methyltransf_11 PF08241.7 EME87180.1 - 1.5e-08 35.0 0.0 2.7e-07 30.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME87180.1 - 7.5e-05 22.5 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME87180.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF1214 PF06742.6 EME87182.1 - 0.078 13.4 0.2 0.47 10.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1214) Ribosomal_S19 PF00203.16 EME87183.1 - 7.6e-35 118.3 0.3 1e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SR-25 PF10500.4 EME87185.1 - 0.00011 21.7 17.8 0.00011 21.7 12.3 4.2 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.14 EME87187.1 - 1.2e-26 93.6 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME87187.1 - 2.2e-08 33.4 1.4 0.00011 21.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME87187.1 - 5.4e-05 23.1 0.3 0.00015 21.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME87187.1 - 6.9e-05 22.8 0.4 0.00014 21.7 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EME87187.1 - 9.8e-05 22.6 0.3 0.0084 16.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME87187.1 - 0.0001 21.0 2.5 0.0051 15.4 0.4 2.3 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EME87187.1 - 0.00051 18.6 0.4 0.0026 16.2 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 EME87187.1 - 0.00095 18.3 0.1 0.0027 16.8 0.0 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EME87187.1 - 0.0015 17.5 1.3 0.0042 15.9 0.8 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EME87187.1 - 0.0025 16.7 0.6 0.0044 15.9 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME87187.1 - 0.0032 16.6 0.2 0.0055 15.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 EME87187.1 - 0.023 14.9 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.11 EME87187.1 - 0.029 13.8 0.1 0.095 12.1 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EME87187.1 - 0.048 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EME87187.1 - 0.051 12.6 0.9 0.096 11.7 0.6 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase NPR3 PF03666.8 EME87188.1 - 7.7e-71 238.9 4.7 5.2e-47 160.4 1.9 2.4 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 PBP1_TM PF14812.1 EME87188.1 - 0.0034 17.6 1.0 0.0093 16.2 0.7 1.7 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3_zeta PF05091.7 EME87189.1 - 1.7e-189 630.7 0.0 2.1e-189 630.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EME87189.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF569) Melibiase PF02065.13 EME87190.1 - 1.4e-35 122.7 0.0 1.7e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 EME87190.1 - 0.0043 15.9 0.0 0.0045 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Dabb PF07876.7 EME87192.1 - 0.057 13.8 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain Herpes_UL73 PF03554.8 EME87192.1 - 0.077 12.8 0.1 0.49 10.2 0.0 2.3 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein p450 PF00067.17 EME87194.1 - 6.9e-43 146.8 0.1 1.4e-29 102.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EME87195.1 - 1e-75 255.0 0.0 1.5e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EME87195.1 - 9.8e-36 123.2 0.0 1.7e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EME87195.1 - 5.1e-26 91.3 0.1 9.8e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EME87195.1 - 1.3e-12 48.2 0.0 6.1e-12 46.0 0.0 2.2 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EME87195.1 - 0.00061 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 NrdI Flavodoxin like NAD_binding_6 PF08030.7 EME87195.1 - 0.012 15.5 0.0 0.81 9.5 0.0 3.3 4 0 0 4 4 4 0 Ferric reductase NAD binding domain Flavodoxin_5 PF12724.2 EME87195.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Transglut_core PF01841.14 EME87195.1 - 0.061 13.5 0.1 0.34 11.1 0.0 2.2 2 1 0 2 2 2 0 Transglutaminase-like superfamily Metallophos PF00149.23 EME87196.1 - 0.0029 17.0 2.5 0.0029 17.0 1.7 2.2 2 2 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1538 PF07556.6 EME87198.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) DUF4023 PF13215.1 EME87200.1 - 0.043 13.5 1.6 0.3 10.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) AA_permease_2 PF13520.1 EME87201.1 - 5.1e-23 81.3 25.8 6.6e-23 80.9 17.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2512 PF10710.4 EME87201.1 - 2.1 7.7 5.1 9.8 5.6 2.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2512) COX6B PF02297.12 EME87202.1 - 1.1e-19 70.2 7.9 1.3e-19 70.0 5.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EME87202.1 - 0.0029 16.9 0.5 0.0049 16.2 0.3 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain B12D PF06522.6 EME87203.1 - 5e-08 32.5 0.0 8.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1212 PF06738.7 EME87203.1 - 0.0058 16.1 0.0 0.0066 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) LtrA PF06772.6 EME87204.1 - 4.2e-08 32.4 10.0 6.4e-08 31.8 6.9 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) His_Phos_2 PF00328.17 EME87205.1 - 1.3e-54 185.8 0.0 1.6e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Beta-lactamase PF00144.19 EME87206.1 - 6.3e-43 147.0 0.2 1.4e-42 145.9 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase AAA_10 PF12846.2 EME87207.1 - 3e-11 43.3 0.0 9.6e-10 38.3 0.0 2.4 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EME87207.1 - 4.4e-06 26.8 0.0 0.0033 17.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain Zot PF05707.7 EME87207.1 - 2e-05 24.1 0.0 0.00054 19.4 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EME87207.1 - 0.0015 18.6 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME87207.1 - 0.0022 18.0 0.0 0.0053 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EME87207.1 - 0.0028 17.1 0.0 0.02 14.3 0.0 2.0 2 1 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EME87207.1 - 0.029 13.4 0.2 0.093 11.8 0.0 1.9 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.12 EME87207.1 - 0.049 13.4 0.1 0.21 11.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF87 AAA_14 PF13173.1 EME87207.1 - 0.068 13.0 0.0 13 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Peptidase_M20 PF01546.23 EME87208.1 - 2.1e-22 79.5 0.0 4e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EME87208.1 - 2e-10 40.1 0.0 0.0017 18.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat M20_dimer PF07687.9 EME87208.1 - 8.4e-08 31.9 0.0 2.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain SelR PF01641.13 EME87209.1 - 3e-51 172.2 0.3 3.4e-51 172.1 0.2 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EME87209.1 - 0.0018 17.9 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 EME87209.1 - 0.0054 16.0 1.6 0.11 11.8 0.1 2.5 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EME87209.1 - 0.0056 16.4 2.2 0.86 9.4 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon GFA PF04828.9 EME87209.1 - 0.022 14.6 1.4 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.9 EME87209.1 - 0.11 12.5 0.9 0.49 10.4 0.7 1.9 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.1 EME87209.1 - 0.17 11.7 2.1 2.1 8.2 0.3 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.1 EME87209.1 - 0.32 10.2 2.5 3.4 6.9 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EME87209.1 - 0.96 9.7 4.0 10 6.4 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 EME87209.1 - 5.4 6.5 5.9 22 4.6 0.3 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Peptidase_M16_C PF05193.16 EME87211.1 - 0.11 12.0 0.6 0.21 11.2 0.4 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain Ndufs5 PF10200.4 EME87212.1 - 0.00023 21.1 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EME87212.1 - 0.0093 16.0 0.2 0.016 15.3 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX17 PF05051.8 EME87212.1 - 0.079 12.9 0.4 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF1793 PF08760.6 EME87213.1 - 9.4e-70 233.9 0.2 1.6e-68 229.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF1761 PF08570.5 EME87216.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Ribosomal_60s PF00428.14 EME87217.1 - 1 9.8 18.8 0.43 11.0 6.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein SNARE PF05739.14 EME87218.1 - 1.8e-13 49.9 7.5 1.8e-13 49.9 5.2 3.0 3 0 0 3 3 3 1 SNARE domain TMCO5 PF14992.1 EME87218.1 - 0.00088 18.4 1.7 0.0093 15.1 0.1 2.2 2 0 0 2 2 2 1 TMCO5 family Syntaxin PF00804.20 EME87218.1 - 0.002 18.2 9.6 0.0023 18.0 0.5 2.9 2 1 0 2 2 2 1 Syntaxin FlxA PF14282.1 EME87218.1 - 0.0029 17.5 1.3 0.0029 17.5 0.9 2.8 2 1 1 3 3 3 1 FlxA-like protein TMPIT PF07851.8 EME87218.1 - 0.004 16.2 2.9 0.11 11.5 0.1 2.1 2 0 0 2 2 2 2 TMPIT-like protein Spectrin PF00435.16 EME87218.1 - 0.0091 16.2 7.3 0.35 11.1 0.0 3.1 3 1 0 3 3 3 1 Spectrin repeat DUF4094 PF13334.1 EME87218.1 - 0.0096 16.2 2.4 0.14 12.5 0.6 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4094) BLOC1_2 PF10046.4 EME87218.1 - 0.045 13.9 5.0 0.13 12.4 0.4 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1993 PF09351.5 EME87218.1 - 0.46 10.3 5.1 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DUF1664 PF07889.7 EME87218.1 - 0.64 9.8 8.2 20 4.9 0.9 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Vps5 PF09325.5 EME87218.1 - 0.86 8.8 9.4 0.16 11.1 0.9 2.8 2 1 1 3 3 3 0 Vps5 C terminal like LUC7 PF03194.10 EME87218.1 - 1 8.8 13.6 47 3.3 9.4 2.4 1 1 0 1 1 1 0 LUC7 N_terminus Mod_r PF07200.8 EME87218.1 - 2.7 7.8 12.9 0.69 9.8 1.7 2.7 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HisKA_3 PF07730.8 EME87218.1 - 3.9 7.8 13.9 2.9 8.3 0.5 3.9 3 1 1 4 4 4 0 Histidine kinase V_ATPase_I PF01496.14 EME87218.1 - 6.7 4.4 10.0 15 3.2 6.3 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.7 EME87218.1 - 9.5 5.9 12.2 4.7 6.9 2.7 3.1 2 1 1 3 3 3 0 Laminin Domain II AMP-binding PF00501.23 EME87219.1 - 1.5e-67 227.7 0.0 2.6e-67 227.0 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME87219.1 - 1.7e-12 48.0 0.0 3.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DnaJ-X PF14308.1 EME87220.1 - 4.9e-71 238.2 1.0 4.9e-71 238.2 0.7 2.7 2 2 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EME87220.1 - 9e-27 92.6 0.8 2.4e-26 91.2 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain U1snRNP70_N PF12220.3 EME87220.1 - 1.6 9.0 14.2 3 8.2 1.2 3.8 3 1 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Menin PF05053.8 EME87221.1 - 0.3 9.2 1.6 0.33 9.0 1.1 1.0 1 0 0 1 1 1 0 Menin DAN PF03045.10 EME87223.1 - 0.13 11.6 1.8 0.11 11.8 0.2 1.7 2 0 0 2 2 2 0 DAN domain DUF3678 PF12435.3 EME87223.1 - 0.3 10.6 0.2 0.3 10.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Pacifastin_I PF05375.8 EME87224.1 - 0.15 11.5 0.3 0.15 11.5 0.2 2.4 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Bcl-2_BAD PF10514.4 EME87226.1 - 1.6 8.6 4.7 37 4.2 3.3 2.1 1 1 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD DDE_Tnp_4 PF13359.1 EME87227.1 - 0.002 17.7 0.0 0.002 17.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease BolA PF01722.13 EME87229.1 - 1.9e-28 98.2 2.0 2.2e-28 97.9 1.4 1.1 1 0 0 1 1 1 1 BolA-like protein Mpv17_PMP22 PF04117.7 EME87230.1 - 7.4e-26 89.5 0.5 1.3e-25 88.7 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family NAPRTase PF04095.11 EME87231.1 - 2.2e-51 174.5 0.1 3.1e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family PHD PF00628.24 EME87234.1 - 3e-08 33.2 12.3 3.4e-08 33.0 8.5 1.1 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EME87234.1 - 0.00061 19.8 7.3 0.00063 19.8 5.0 1.2 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EME87234.1 - 0.0014 18.6 4.4 0.0014 18.5 3.0 1.1 1 0 0 1 1 1 1 PHD-zinc-finger like domain DNA_ligase_ZBD PF03119.11 EME87234.1 - 0.067 12.9 0.3 0.067 12.9 0.2 1.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain FANCL_C PF11793.3 EME87234.1 - 0.75 9.8 6.6 0.84 9.6 4.6 1.2 1 0 0 1 1 1 0 FANCL C-terminal domain zf-piccolo PF05715.8 EME87234.1 - 1.3 9.0 6.2 1.6 8.7 4.3 1.2 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING-like PF08746.6 EME87234.1 - 1.7 8.7 10.5 2.9 7.9 7.3 1.5 1 1 0 1 1 1 0 RING-like domain PHD_2 PF13831.1 EME87234.1 - 6.8 6.0 10.6 0.39 10.0 3.9 1.7 2 1 0 2 2 2 0 PHD-finger E1-E2_ATPase PF00122.15 EME87235.1 - 1.2e-12 47.4 0.0 1.2e-12 47.4 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EME87235.1 - 8.3e-12 45.6 0.0 3.6e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME87235.1 - 1.3e-11 44.2 0.0 3.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EME87235.1 - 3.6e-09 37.3 0.5 7.9e-08 32.9 0.3 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME87235.1 - 0.0087 15.6 0.2 0.021 14.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CBP4 PF07960.6 EME87236.1 - 3.6e-31 107.4 0.5 3.8e-31 107.3 0.3 1.0 1 0 0 1 1 1 1 CBP4 Med1 PF10744.4 EME87236.1 - 0.015 14.0 0.2 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 ERCC4 PF02732.10 EME87238.1 - 2e-23 82.7 0.0 4.6e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 EME87238.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain TatD_DNase PF01026.16 EME87239.1 - 5.2e-10 38.9 0.0 7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase UQ_con PF00179.21 EME87241.1 - 9.1e-47 158.0 0.0 1e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME87241.1 - 1.1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EME87241.1 - 0.069 12.8 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 UEV domain WD40 PF00400.27 EME87242.1 - 6.4e-06 25.8 5.0 7.5e-05 22.4 0.6 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 EME87242.1 - 0.0017 18.1 10.0 0.004 16.9 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME87242.1 - 0.59 9.8 10.1 1.3 8.7 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME87242.1 - 2.4 7.9 12.8 5.1 6.9 8.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain HET PF06985.6 EME87243.1 - 2.1e-18 66.8 7.0 6.8e-15 55.4 0.7 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sigma70_r4_2 PF08281.7 EME87244.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF605 PF04652.11 EME87244.1 - 0.78 9.0 10.9 0.86 8.9 7.6 1.1 1 0 0 1 1 1 0 Vta1 like Exo_endo_phos PF03372.18 EME87245.1 - 7.1e-09 35.9 0.1 9.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-B_box PF00643.19 EME87246.1 - 0.12 12.2 6.2 0.29 11.0 1.3 2.8 2 0 0 2 2 2 0 B-box zinc finger ADH_N PF08240.7 EME87247.1 - 2.8e-10 39.9 1.2 6.5e-06 25.8 0.8 3.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME87247.1 - 0.0053 16.3 0.2 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EME87247.1 - 0.0055 16.2 0.1 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME87247.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME87247.1 - 0.023 14.0 0.1 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 3HCDH_N PF02737.13 EME87247.1 - 0.049 13.2 0.2 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EME87247.1 - 0.088 13.2 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EME87247.1 - 0.36 10.6 1.7 0.86 9.4 1.0 1.7 2 0 0 2 2 2 0 ThiF family Zn_clus PF00172.13 EME87248.1 - 2.3e-10 40.2 7.4 4e-10 39.4 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMC_N PF02463.14 EME87249.1 - 3.8e-22 78.6 0.0 7e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EME87249.1 - 7.5e-22 78.6 0.0 7.5e-22 78.6 0.0 5.3 3 2 0 3 3 1 1 AAA domain AAA_21 PF13304.1 EME87249.1 - 9.5e-07 29.0 0.9 0.00015 21.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain TMF_TATA_bd PF12325.3 EME87249.1 - 0.00048 19.8 8.5 0.00048 19.8 5.9 6.9 3 2 4 7 7 4 1 TATA element modulatory factor 1 TATA binding AAA_29 PF13555.1 EME87249.1 - 0.0017 17.8 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF972 PF06156.8 EME87249.1 - 0.0032 17.7 4.6 0.0032 17.7 3.2 7.2 5 1 2 7 7 7 1 Protein of unknown function (DUF972) AAA_25 PF13481.1 EME87249.1 - 0.0032 16.8 0.0 0.019 14.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain Seryl_tRNA_N PF02403.17 EME87249.1 - 0.0033 17.4 9.2 0.0033 17.4 6.4 6.5 3 2 2 6 6 5 2 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 EME87249.1 - 0.014 15.2 13.3 3.3 7.5 2.8 4.8 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_19 PF13245.1 EME87249.1 - 0.12 12.0 0.0 0.47 10.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_13 PF13166.1 EME87249.1 - 0.13 10.6 0.0 0.13 10.6 0.0 4.9 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.22 EME87249.1 - 3 8.1 21.2 1.2 9.4 4.6 4.9 3 2 0 3 3 3 0 ABC transporter POP1 PF06978.6 EME87250.1 - 2.6e-61 206.5 17.5 2.6e-61 206.5 12.1 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EME87250.1 - 6.2e-30 102.8 2.1 6.2e-30 102.8 1.5 2.7 2 0 0 2 2 2 1 POPLD (NUC188) domain Pkinase PF00069.20 EME87252.1 - 2e-67 227.0 0.0 3.5e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87252.1 - 9.3e-30 103.5 0.0 2.8e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EME87252.1 - 5e-06 26.4 0.2 5.2e-05 23.0 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME87252.1 - 5.2e-05 22.9 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EME87252.1 - 0.00029 19.9 0.0 0.00068 18.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EME87252.1 - 0.0042 16.4 0.1 0.035 13.4 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EME87252.1 - 0.056 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF1679 PF07914.6 EME87252.1 - 0.22 10.1 0.0 0.59 8.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2951 PF11166.3 EME87252.1 - 0.34 10.7 1.1 3.1 7.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2 PF00096.21 EME87253.1 - 1.6e-11 43.8 13.1 1.1e-05 25.5 1.2 2.8 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME87253.1 - 6.8e-10 38.5 7.3 6.3e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME87253.1 - 1.7e-09 37.5 10.5 5.3e-07 29.6 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EME87253.1 - 0.0032 17.2 6.1 0.076 12.9 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EME87253.1 - 0.0055 16.8 2.0 0.0055 16.8 1.4 2.9 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EME87253.1 - 0.013 15.6 8.1 0.026 14.6 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EME87253.1 - 0.038 13.7 2.7 0.19 11.5 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EME87253.1 - 0.089 12.9 2.6 0.15 12.1 1.8 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-met PF12874.2 EME87253.1 - 0.14 12.3 0.1 0.14 12.3 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PAT1 PF09770.4 EME87253.1 - 6.7 4.8 8.9 7.5 4.6 6.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PTCB-BRCT PF12738.2 EME87255.1 - 3.9e-13 49.0 0.0 9.3e-13 47.8 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EME87255.1 - 1.1e-07 31.8 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EME87255.1 - 4.9e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EME87255.1 - 0.00016 21.3 0.0 0.00037 20.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Med1 PF10744.4 EME87257.1 - 0.049 12.3 0.1 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 DUF2363 PF10155.4 EME87257.1 - 0.055 13.4 0.2 0.07 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) L1R_F9L PF02442.12 EME87257.1 - 0.077 12.4 0.1 0.084 12.3 0.1 1.0 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Malate_synthase PF01274.17 EME87259.1 - 2.3e-226 751.8 0.1 2.6e-226 751.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF1689 PF07954.6 EME87260.1 - 0.0077 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Romo1 PF10247.4 EME87260.1 - 0.013 15.7 0.1 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 HK97-gp10_like PF04883.7 EME87260.1 - 0.07 14.0 0.4 19 6.2 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Spore_III_AB PF09548.5 EME87260.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Malate_DH PF12434.3 EME87260.1 - 1.6 8.5 5.1 0.27 10.9 0.4 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Methyltransf_3 PF01596.12 EME87261.1 - 8.9e-33 113.0 0.0 1e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EME87261.1 - 5.2e-12 46.5 0.0 9.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87261.1 - 6.9e-08 33.0 0.0 1.2e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME87261.1 - 0.00013 22.0 0.0 0.00021 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EME87261.1 - 0.00082 18.7 0.1 0.0029 16.9 0.0 1.8 2 1 0 2 2 2 1 Cephalosporin hydroxylase Methyltransf_31 PF13847.1 EME87261.1 - 0.0011 18.6 0.0 0.005 16.4 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EME87261.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EME87261.1 - 0.0066 15.8 0.1 0.016 14.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain 3HCDH_N PF02737.13 EME87261.1 - 0.022 14.4 0.3 0.62 9.6 0.0 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.3 EME87262.1 - 2.6e-53 181.0 0.0 3.6e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME87262.1 - 5.4e-06 26.2 7.8 9.7e-06 25.4 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtIP_N PF10482.4 EME87262.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DEAD PF00270.24 EME87267.1 - 5.8e-37 126.7 0.3 9.5e-37 126.0 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME87267.1 - 3.8e-10 39.5 0.1 0.00013 21.7 0.0 3.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EME87267.1 - 3.7e-06 26.8 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Metallophos PF00149.23 EME87269.1 - 7.6e-07 28.7 0.6 2.6e-06 26.9 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME87269.1 - 1e-06 28.6 0.1 2.5e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DnaJ PF00226.26 EME87270.1 - 1.1e-20 73.1 0.8 2.7e-20 71.8 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain GST_C_3 PF14497.1 EME87271.1 - 1.1e-10 41.9 0.1 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME87271.1 - 9.1e-09 35.1 0.1 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME87271.1 - 8e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NT-C2 PF10358.4 EME87272.1 - 1.4e-29 102.3 0.0 2.3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins GST_C PF00043.20 EME87274.1 - 8.5e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EME87274.1 - 1.7e-05 24.9 0.1 3.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME87274.1 - 2.4e-05 24.1 0.1 4.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DSPc PF00782.15 EME87275.1 - 3.2e-25 88.2 0.0 1.2e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME87275.1 - 0.0067 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RPEL PF02755.10 EME87276.1 - 3.3e-20 70.7 16.4 1.5e-07 30.4 0.9 3.9 4 0 0 4 4 4 3 RPEL repeat Rotamase_3 PF13616.1 EME87276.1 - 0.025 14.8 3.3 1.3 9.2 0.5 2.1 1 1 1 2 2 2 0 PPIC-type PPIASE domain SIP PF04954.8 EME87276.1 - 0.09 13.1 0.1 20 5.5 0.0 2.3 2 0 0 2 2 2 0 Siderophore-interacting protein DUF1992 PF09350.5 EME87276.1 - 0.11 12.3 4.9 1.5 8.7 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1992) Bac_rhodopsin PF01036.13 EME87277.1 - 1.9e-49 167.9 19.7 2.2e-49 167.7 13.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SUR7 PF06687.7 EME87277.1 - 0.12 11.9 4.7 0.23 11.0 0.1 2.2 2 0 0 2 2 2 0 SUR7/PalI family Zn_clus PF00172.13 EME87280.1 - 0.032 14.1 2.1 0.066 13.1 1.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rpr2 PF04032.11 EME87281.1 - 2e-14 53.1 2.0 2.5e-14 52.9 1.4 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S27e PF01667.12 EME87281.1 - 0.0069 15.8 1.2 0.49 9.9 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein S27 RPA_interact_C PF14768.1 EME87281.1 - 0.015 15.6 1.0 0.02 15.2 0.7 1.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal DUF2387 PF09526.5 EME87281.1 - 0.051 13.5 0.3 0.092 12.6 0.0 1.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) RNHCP PF12647.2 EME87281.1 - 0.18 11.6 2.5 0.55 10.0 1.7 1.8 1 1 1 2 2 2 0 RNHCP domain PocR PF10114.4 EME87281.1 - 0.23 10.5 1.4 0.31 10.1 0.9 1.1 1 0 0 1 1 1 0 Sensory domain found in PocR Yippee-Mis18 PF03226.9 EME87281.1 - 0.41 10.7 2.6 1.4 9.0 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.27 EME87282.1 - 3.4e-22 77.4 2.2 4.6e-08 32.6 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EME87282.1 - 0.065 12.7 0.0 0.77 9.3 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EME87282.1 - 0.099 12.3 0.0 0.3 10.7 0.0 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF1793 PF08760.6 EME87283.1 - 3.6e-65 218.9 0.5 9.9e-65 217.5 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EME87283.1 - 9.6e-05 21.6 0.0 0.00023 20.3 0.0 1.7 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal EBV-NA1 PF02905.9 EME87284.1 - 0.51 9.8 3.0 4.8 6.6 0.2 2.0 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain MFS_1 PF07690.11 EME87286.1 - 1.1e-37 129.6 25.4 1.1e-37 129.6 17.6 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME87286.1 - 5.5e-11 41.6 8.1 5.5e-11 41.6 5.6 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EME87286.1 - 6.3e-09 34.5 5.4 1e-08 33.8 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AhpC-TSA PF00578.16 EME87287.1 - 1.4e-32 111.9 0.0 1.9e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME87287.1 - 5.1e-13 48.7 0.0 6.6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EME87287.1 - 3.5e-11 42.5 0.1 6.7e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.1 EME87289.1 - 1.7e-20 72.6 4.3 9.6e-10 38.3 0.0 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EME87289.1 - 1.2e-19 69.7 1.6 2.4e-10 40.0 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EME87289.1 - 3.5e-12 45.9 3.3 3e-05 23.8 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EME87289.1 - 2.5e-11 42.9 0.1 0.0065 15.9 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EME87289.1 - 3.3e-10 39.6 0.3 0.001 19.1 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EME87289.1 - 2.1e-08 33.5 0.1 0.017 14.8 0.0 4.2 4 0 0 4 4 4 2 Kelch motif BTB PF00651.26 EME87289.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain RAG2 PF03089.9 EME87289.1 - 0.081 11.6 0.0 0.25 10.0 0.0 1.8 1 1 0 1 1 1 0 Recombination activating protein 2 DNA_pol_B_palm PF14792.1 EME87290.1 - 2.5e-31 108.0 0.0 5.9e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EME87290.1 - 1.2e-22 79.3 0.0 2.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EME87290.1 - 4.7e-19 68.3 0.9 1e-18 67.2 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EME87290.1 - 5.9e-19 67.3 0.3 1.2e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 EME87290.1 - 2.2e-05 24.6 0.0 6.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.21 EME87290.1 - 0.00032 20.8 0.0 0.00087 19.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Sld5 PF05916.6 EME87291.1 - 9.9e-11 41.8 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 EME87291.1 - 0.088 12.3 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DUF463 PF04317.7 EME87291.1 - 0.097 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 HpcH_HpaI PF03328.9 EME87293.1 - 1.5e-32 112.2 0.1 1.9e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PDCD9 PF07147.7 EME87293.1 - 0.063 12.0 0.1 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF836 PF05768.9 EME87294.1 - 1.5e-14 53.9 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EME87294.1 - 0.0045 16.9 0.0 0.008 16.1 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin PcfJ PF14284.1 EME87294.1 - 0.055 12.9 0.5 0.072 12.5 0.3 1.2 1 0 0 1 1 1 0 PcfJ-like protein Thioredoxin_2 PF13098.1 EME87294.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain CHORD PF04968.7 EME87295.1 - 6.9e-47 157.5 21.6 4.4e-26 90.9 4.8 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EME87295.1 - 1.8e-13 50.8 0.2 3.9e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 CS domain HCO3_cotransp PF00955.16 EME87297.1 - 8.7e-57 192.9 6.7 2.3e-35 122.2 3.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Zn_clus PF00172.13 EME87298.1 - 2.9e-07 30.2 11.4 4.7e-07 29.6 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.12 EME87299.1 - 4e-36 123.3 0.0 9.8e-36 122.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EME87299.1 - 1.9e-26 91.9 0.0 5.8e-26 90.3 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EME87299.1 - 3.5e-05 23.0 2.5 0.00011 21.4 0.3 3.2 2 0 0 2 2 2 1 Ubiquitin interaction motif zf-CCHC PF00098.18 EME87300.1 - 1.8e-11 43.3 9.7 1.6e-05 24.5 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EME87300.1 - 1.8e-08 33.9 0.1 3.2e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EME87300.1 - 2.7e-07 30.1 5.9 0.0001 21.9 2.2 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EME87300.1 - 1e-05 25.0 0.1 2.5e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EME87300.1 - 0.0014 18.2 6.0 0.43 10.2 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EME87300.1 - 0.0015 18.1 9.7 0.061 12.9 0.2 2.9 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.1 EME87300.1 - 0.066 12.7 0.2 0.066 12.7 0.1 3.5 3 1 1 4 4 4 0 Zinc knuckle Acetyltransf_9 PF13527.1 EME87301.1 - 3.5e-07 30.1 0.0 4.4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME87301.1 - 0.00032 20.6 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME87301.1 - 0.0005 20.1 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME87301.1 - 0.00091 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME87301.1 - 0.0061 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EME87301.1 - 0.0061 16.6 0.0 0.0073 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME87301.1 - 0.051 13.4 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain A_deaminase PF00962.17 EME87302.1 - 9.3e-114 379.7 2.4 2.5e-113 378.3 0.2 2.0 2 0 0 2 2 2 2 Adenosine/AMP deaminase COesterase PF00135.23 EME87303.1 - 2.4e-61 208.0 0.0 3.9e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EME87303.1 - 1.5e-08 34.4 0.0 7.4e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME87303.1 - 0.013 15.4 0.1 0.032 14.1 0.0 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME87303.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ATP-synt_E PF05680.7 EME87304.1 - 4.1e-18 65.1 0.0 4.2e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.27 EME87305.1 - 1.5e-15 56.3 12.8 2.2e-08 33.6 0.1 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Beta_elim_lyase PF01212.16 EME87306.1 - 1.8e-70 237.3 0.0 2.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EME87306.1 - 5.5e-05 21.6 0.0 8.2e-05 21.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TCR PF03638.10 EME87306.1 - 0.17 11.7 0.8 0.33 10.8 0.5 1.4 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain FAD_binding_3 PF01494.14 EME87307.1 - 4.4e-79 266.1 0.0 5.7e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME87307.1 - 0.00016 21.5 0.0 0.00043 20.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME87307.1 - 0.75 9.8 3.0 2.4 8.2 2.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EME87309.1 - 9.4e-16 58.1 0.1 1.5e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME87309.1 - 1.6e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME87309.1 - 4.4e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 1 0 1 1 1 1 KR domain JAB PF01398.16 EME87311.1 - 0.032 13.9 0.6 0.032 13.9 0.4 1.5 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1752 PF08550.5 EME87314.1 - 8.6e-07 28.4 3.3 2e-06 27.2 2.3 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ELMO_CED12 PF04727.8 EME87315.1 - 5e-40 136.8 0.0 1.1e-39 135.7 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family SH3BGR PF04908.10 EME87317.1 - 0.00011 22.1 0.0 0.00038 20.3 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EME87317.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin zf-GRF PF06839.7 EME87318.1 - 2.5e-08 33.6 7.2 4.4e-08 32.9 5.0 1.4 1 0 0 1 1 1 1 GRF zinc finger ICAP-1_inte_bdg PF10480.4 EME87320.1 - 3.6 7.3 7.2 4.1 7.1 5.0 1.1 1 0 0 1 1 1 0 Beta-1 integrin binding protein Na_trans_assoc PF06512.8 EME87321.1 - 0.32 10.9 4.0 0.16 11.8 0.9 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated OSCP PF00213.13 EME87322.1 - 6.6e-44 149.8 6.8 7.9e-44 149.5 4.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ISG65-75 PF11727.3 EME87322.1 - 0.073 12.1 2.3 0.065 12.2 0.6 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF148 PF02520.12 EME87322.1 - 0.11 12.2 7.6 0.74 9.6 3.6 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 vATP-synt_E PF01991.13 EME87322.1 - 0.17 11.1 5.7 0.31 10.2 3.9 1.5 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Ribosomal_L7Ae PF01248.21 EME87323.1 - 4.2e-20 71.0 0.9 4.2e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Merozoite_SPAM PF07133.6 EME87323.1 - 2.2 8.1 11.1 2.6 7.8 6.7 1.7 1 1 1 2 2 2 0 Merozoite surface protein (SPAM) Abhydrolase_6 PF12697.2 EME87324.1 - 5.9e-20 72.1 0.0 8.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME87324.1 - 8.9e-07 28.7 0.0 1.6e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L30 PF00327.15 EME87325.1 - 2.7e-10 39.6 0.1 4.3e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.8 EME87326.1 - 6.8e-152 506.4 9.3 1e-151 505.8 6.4 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 polyprenyl_synt PF00348.12 EME87327.1 - 2.5e-53 180.6 0.0 5.6e-53 179.4 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase DUF4401 PF14351.1 EME87328.1 - 0.067 12.1 5.4 0.079 11.9 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1625 PF07787.7 EME87328.1 - 0.071 12.3 0.5 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DUF2393 PF09624.5 EME87328.1 - 0.15 11.6 0.9 4.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) DUF4131 PF13567.1 EME87328.1 - 1.1 8.6 9.1 1.4 8.2 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) 2TM PF13239.1 EME87328.1 - 1.1 9.3 5.1 2.1 8.4 1.2 2.1 1 1 1 2 2 2 0 2TM domain zf-C2H2 PF00096.21 EME87329.1 - 0.014 15.6 3.9 0.92 9.9 0.0 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME87329.1 - 8.1 7.0 17.9 0.86 10.0 1.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger GSHPx PF00255.14 EME87330.1 - 2.1e-39 133.1 0.0 2.8e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EME87330.1 - 2.5e-06 27.2 0.1 4.3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 EME87330.1 - 6.3e-06 26.2 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.5 EME87330.1 - 0.0007 19.1 0.1 0.0009 18.7 0.1 1.4 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EME87330.1 - 0.0048 16.5 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 SCO1/SenC CMD PF02627.15 EME87331.1 - 9.1e-11 41.4 0.1 1.8e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF3115 PF11312.3 EME87332.1 - 4.7e-94 314.8 0.0 5.9e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Methyltransf_12 PF08242.7 EME87332.1 - 0.0052 17.2 0.0 0.024 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Lipase_GDSL_2 PF13472.1 EME87332.1 - 0.052 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Metallophos PF00149.23 EME87333.1 - 0.048 13.0 0.1 0.061 12.7 0.1 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Spermine_synth PF01564.12 EME87334.1 - 2.8e-100 334.3 0.0 3.7e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EME87334.1 - 0.00013 22.5 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87334.1 - 0.00049 19.7 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EME87334.1 - 0.0027 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EME87334.1 - 0.0089 16.4 0.1 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EME87334.1 - 0.02 14.1 0.3 0.083 12.0 0.1 2.0 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 EME87334.1 - 0.021 15.6 0.0 0.042 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EME87334.1 - 0.037 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF1841 PF08897.6 EME87334.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Methyltransf_11 PF08241.7 EME87334.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pmp3 PF01679.12 EME87335.1 - 3e-26 90.8 6.4 3.3e-26 90.7 4.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EME87335.1 - 3.4 7.4 9.7 0.26 10.9 2.3 1.9 2 0 0 2 2 2 0 Conserved TM helix DUF1212 PF06738.7 EME87336.1 - 7.6e-51 172.3 9.1 1.2e-47 161.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EME87336.1 - 1.6e-23 83.0 35.1 1.9e-14 53.7 3.6 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF3815) DUF373 PF04123.8 EME87336.1 - 0.018 14.0 3.6 0.032 13.2 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2301 PF10063.4 EME87336.1 - 0.11 12.7 5.2 0.03 14.5 1.2 1.8 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) NAD_kinase PF01513.16 EME87337.1 - 4e-70 235.8 0.0 5.5e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase CsbD PF05532.7 EME87339.1 - 3.7e-14 52.1 29.5 2.8e-08 33.3 0.8 3.5 2 1 1 3 3 3 3 CsbD-like Fungal_trans PF04082.13 EME87340.1 - 9e-30 103.4 0.1 1.8e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME87340.1 - 2.2e-08 33.8 14.9 3.8e-08 33.0 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSPn PF14671.1 EME87342.1 - 9.3e-42 142.3 0.0 2.2e-38 131.4 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EME87342.1 - 4.2e-16 58.7 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EME87342.1 - 4.7e-06 26.1 0.1 1.3e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase FAD_binding_3 PF01494.14 EME87343.1 - 5.6e-10 38.7 0.1 0.0002 20.5 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EME87343.1 - 1.2e-09 37.5 0.1 5.6e-05 22.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME87343.1 - 1.8e-09 37.0 0.1 1.2e-08 34.2 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME87343.1 - 2.1e-08 34.2 0.3 1.1e-07 32.0 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME87343.1 - 5.5e-07 28.3 0.2 0.00065 18.2 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EME87343.1 - 1.1e-05 25.6 0.1 0.00011 22.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME87343.1 - 2.5e-05 24.2 0.0 7.8e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EME87343.1 - 0.0001 21.2 0.1 0.0046 15.8 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EME87343.1 - 0.00018 20.7 1.2 0.0004 19.6 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EME87343.1 - 0.00054 19.5 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EME87343.1 - 0.00065 20.0 0.0 0.043 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME87343.1 - 0.0015 17.6 0.0 0.004 16.2 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EME87343.1 - 0.0061 15.5 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EME87343.1 - 0.0096 15.7 0.2 6 6.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EME87343.1 - 0.043 12.8 0.5 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_10 PF13460.1 EME87343.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DDE_Tnp_IS1595 PF12762.2 EME87343.1 - 0.073 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 ISXO2-like transposase domain 3HCDH_N PF02737.13 EME87343.1 - 0.11 12.1 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 EME87344.1 - 3.8e-55 187.2 0.0 5.3e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.1 EME87344.1 - 0.0094 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Stirrup CDC14 PF08045.6 EME87345.1 - 2.4e-87 292.3 0.7 2.8e-87 292.1 0.5 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Myotub-related PF06602.9 EME87346.1 - 1.4e-110 369.4 0.0 3.1e-110 368.2 0.0 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EME87346.1 - 0.031 14.5 0.2 0.43 10.7 0.0 2.3 1 1 1 2 2 2 0 Tyrosine phosphatase family Nfu_N PF08712.6 EME87348.1 - 1.4e-26 91.9 0.0 9.4e-26 89.2 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EME87348.1 - 2.2e-22 78.6 0.1 3.6e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain RNB PF00773.14 EME87349.1 - 7.8e-92 308.0 0.3 1.5e-91 307.0 0.1 1.6 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 EME87349.1 - 1.4e-07 31.6 0.1 1.4e-07 31.6 0.1 2.6 3 1 1 4 4 4 1 PIN domain TP_methylase PF00590.15 EME87350.1 - 0.0083 15.8 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases HTH_11 PF08279.7 EME87350.1 - 0.067 12.8 0.0 17 5.1 0.0 2.6 2 0 0 2 2 2 0 HTH domain Zn_clus PF00172.13 EME87351.1 - 0.17 11.8 9.7 0.29 11.0 6.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MS_channel PF00924.13 EME87354.1 - 2.7e-13 49.7 0.5 5e-13 48.8 0.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EME87354.1 - 0.00033 19.7 0.5 0.0016 17.5 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EME87354.1 - 0.004 16.9 0.1 0.041 13.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EME87354.1 - 0.0079 15.4 0.2 0.36 10.2 0.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EME87354.1 - 0.014 15.5 0.1 0.057 13.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair FAD_binding_3 PF01494.14 EME87355.1 - 9.8e-71 238.6 0.0 1.4e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EME87355.1 - 1.3e-27 96.4 0.0 2.9e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Lycopene_cycl PF05834.7 EME87355.1 - 0.0028 16.6 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EME87355.1 - 0.1 11.5 0.2 6.9 5.4 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 EME87355.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EME87355.1 - 0.14 11.9 0.0 1.5 8.6 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.16 EME87356.1 - 1.5e-91 307.5 0.0 1.7e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 EME87357.1 - 7.4e-12 44.5 0.0 2.1e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lyase_catalyt PF09093.6 EME87357.1 - 0.18 10.6 0.2 0.36 9.6 0.1 1.4 1 0 0 1 1 1 0 Lyase, catalytic HsbA PF12296.3 EME87359.1 - 1.5e-22 79.7 9.9 3.8e-22 78.4 6.9 1.7 1 0 0 1 1 1 1 Hydrophobic surface binding protein A PIR PF00399.14 EME87359.1 - 0.00013 21.1 0.4 0.0011 18.2 0.3 2.7 1 0 0 1 1 1 1 Yeast PIR protein repeat Resistin PF06954.6 EME87360.1 - 0.079 13.2 2.1 0.17 12.1 1.5 1.6 1 0 0 1 1 1 0 Resistin TFIIF_beta PF02270.10 EME87361.1 - 1e-52 179.6 2.3 1.3e-52 179.3 1.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 EME87361.1 - 0.0016 17.8 1.1 0.002 17.5 0.8 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH_32 PF13565.1 EME87361.1 - 0.015 16.0 0.1 0.049 14.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain PYRIN PF02758.11 EME87361.1 - 0.04 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Rox3 PF08633.5 EME87362.1 - 6.1e-32 111.5 1.4 1.8e-31 109.9 0.9 1.7 1 1 0 1 1 1 1 Rox3 mediator complex subunit Dispanin PF04505.7 EME87363.1 - 0.24 10.9 0.1 0.24 10.9 0.1 1.5 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Rad10 PF03834.9 EME87364.1 - 7.3e-31 105.6 0.1 1.3e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EME87364.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain BOP1NT PF08145.7 EME87365.1 - 1.2e-101 339.8 5.4 1.2e-101 339.8 3.8 2.0 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EME87365.1 - 2.5e-35 119.0 7.3 5.7e-12 45.0 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Zn_clus PF00172.13 EME87366.1 - 9e-11 41.5 9.8 9e-11 41.5 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD_assoc PF08494.6 EME87366.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 DEAD/H associated Oxidored_FMN PF00724.15 EME87367.1 - 2.2e-47 161.7 0.0 2.7e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Piwi PF02171.12 EME87368.1 - 1e-62 211.8 0.0 1.2e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Ribosomal_L7Ae PF01248.21 EME87369.1 - 2.2e-25 87.9 0.1 2.6e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EME87369.1 - 0.0015 18.3 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EME87369.1 - 0.094 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain ATP-synt_C PF00137.16 EME87370.1 - 5.8e-33 112.6 29.7 1.3e-18 66.6 8.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EME87370.1 - 0.12 11.9 4.0 0.051 13.1 0.8 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EME87370.1 - 0.92 8.6 2.9 3.7 6.6 0.1 2.0 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2970 PF11174.3 EME87370.1 - 2.5 7.7 9.5 0.33 10.5 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF2244 PF10003.4 EME87370.1 - 5.1 6.4 7.8 0.18 11.1 0.4 2.2 2 1 1 3 3 3 0 Integral membrane protein (DUF2244) ADH_N PF08240.7 EME87371.1 - 5.1e-28 97.0 4.9 5.1e-28 97.0 3.4 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME87371.1 - 6.5e-18 64.5 0.5 1.2e-17 63.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME87371.1 - 0.016 14.5 0.1 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EME87371.1 - 0.024 14.4 0.3 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 ThiF family Saccharop_dh PF03435.13 EME87371.1 - 0.03 13.3 0.2 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase FKBP_C PF00254.23 EME87371.1 - 0.038 14.0 0.1 4.5 7.3 0.0 2.7 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Pyr_redox_3 PF13738.1 EME87371.1 - 0.068 13.2 0.1 0.15 12.0 0.1 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 EME87371.1 - 0.087 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GAF_2 PF13185.1 EME87372.1 - 5.6e-08 33.4 0.0 8.5e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EME87372.1 - 0.00011 22.3 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EME87372.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 GAF domain AAA_11 PF13086.1 EME87373.1 - 6.8e-62 209.1 0.3 1.6e-61 207.8 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EME87373.1 - 9.5e-58 194.8 0.0 1.2e-56 191.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME87373.1 - 9.7e-13 47.6 0.0 4.9e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EME87373.1 - 7.4e-12 45.2 1.1 5.8e-10 39.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EME87373.1 - 2.4e-08 33.6 0.2 1.2e-07 31.3 0.0 2.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EME87373.1 - 5.3e-08 32.2 0.9 6.8e-07 28.5 0.6 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C PF13361.1 EME87373.1 - 9.7e-08 31.8 0.0 0.0012 18.3 0.0 3.4 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain ResIII PF04851.10 EME87373.1 - 3.9e-07 30.0 0.0 1.1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EME87373.1 - 6.8e-07 29.0 0.1 0.31 10.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EME87373.1 - 1.1e-05 24.7 0.0 0.004 16.4 0.0 2.6 2 1 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EME87373.1 - 5e-05 23.4 0.2 0.00061 19.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME87373.1 - 0.00023 21.1 0.1 0.0034 17.3 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain PIF1 PF05970.9 EME87373.1 - 0.0003 19.8 0.0 0.42 9.5 0.0 2.6 3 0 0 3 3 3 2 PIF1-like helicase DEAD PF00270.24 EME87373.1 - 0.0003 20.3 0.7 0.0014 18.1 0.5 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EME87373.1 - 0.00044 20.3 0.1 1.5 8.9 0.0 3.1 3 0 0 3 3 2 2 UvrD-like helicase C-terminal domain T2SE PF00437.15 EME87373.1 - 0.00078 18.4 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EME87373.1 - 0.0015 18.0 0.4 0.0061 16.0 0.3 2.0 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EME87373.1 - 0.0026 17.2 0.0 0.015 14.6 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EME87373.1 - 0.0039 16.9 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EME87373.1 - 0.0065 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EME87373.1 - 0.0071 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EME87373.1 - 0.0076 16.5 0.0 0.031 14.5 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 EME87373.1 - 0.0085 16.2 0.2 0.03 14.5 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 EME87373.1 - 0.0092 15.7 0.5 0.027 14.2 0.0 2.0 3 0 0 3 3 1 1 Flavivirus DEAD domain AAA_33 PF13671.1 EME87373.1 - 0.02 14.7 0.1 0.065 13.1 0.0 2.0 2 1 0 2 2 1 0 AAA domain 4HB_MCP_1 PF12729.2 EME87373.1 - 0.025 13.9 0.2 0.051 12.9 0.2 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_17 PF13207.1 EME87373.1 - 0.026 15.3 0.6 0.085 13.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EME87373.1 - 0.058 13.0 0.1 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Zot PF05707.7 EME87373.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.10 EME87373.1 - 0.09 12.4 1.1 0.68 9.6 0.0 2.7 3 0 0 3 3 2 0 NTPase PaRep2a PF07903.6 EME87375.1 - 0.049 13.2 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 PaRep2a protein Rhomboid PF01694.17 EME87376.1 - 1.5e-21 76.9 13.1 2.5e-21 76.2 8.5 1.7 2 0 0 2 2 2 1 Rhomboid family RGS PF00615.14 EME87377.1 - 5e-08 33.0 0.0 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Fibrillarin PF01269.12 EME87377.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Acetyltransf_7 PF13508.1 EME87379.1 - 1.1e-10 41.5 0.3 1.4e-10 41.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME87379.1 - 2.8e-10 40.0 0.1 4e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EME87379.1 - 0.0039 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME87379.1 - 0.022 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME87379.1 - 0.085 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AdoMet_MTase PF07757.8 EME87380.1 - 4.1e-40 136.3 0.0 7.1e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EME87380.1 - 0.019 14.6 0.0 0.065 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME87380.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EME87380.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_2 PF00152.15 EME87382.1 - 1e-105 353.2 0.0 1.2e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EME87382.1 - 5.3e-06 26.1 0.1 1.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EME87382.1 - 0.012 14.7 0.2 0.038 13.1 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EME87382.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Aldedh PF00171.17 EME87383.1 - 1.2e-184 613.9 0.2 1.4e-184 613.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME87383.1 - 0.071 12.3 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LSM PF01423.17 EME87384.1 - 1.5e-06 27.6 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Stb3 PF10330.4 EME87387.1 - 1.5e-30 104.7 0.0 3.2e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein NAD_binding_6 PF08030.7 EME87388.1 - 8.9e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME87388.1 - 2e-15 56.9 7.8 2e-15 56.9 5.4 1.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME87388.1 - 1e-10 41.3 0.0 2.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 EME87388.1 - 5.9e-06 26.3 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EME87388.1 - 0.007 16.9 0.0 1.4 9.5 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain zf-CpG_bind_C PF12269.3 EME87390.1 - 0.018 14.5 2.0 0.096 12.1 0.2 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain RWP-RK PF02042.10 EME87390.1 - 2.3 8.1 7.2 2.7 7.8 3.9 1.9 2 0 0 2 2 2 0 RWP-RK domain Steroid_dh PF02544.11 EME87391.1 - 6.7e-14 51.9 0.2 1.5e-13 50.7 0.1 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EME87391.1 - 4.3e-05 22.9 1.4 5.8e-05 22.5 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NAD_binding_10 PF13460.1 EME87392.1 - 7.6e-10 39.0 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EME87392.1 - 6.2e-05 22.3 0.0 0.001 18.3 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EME87392.1 - 0.00046 19.6 0.0 0.0014 18.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME87392.1 - 0.099 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein B3_4 PF03483.12 EME87394.1 - 1.1e-21 77.1 0.1 1.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EME87394.1 - 7.8e-17 60.8 0.0 2.2e-12 46.6 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EME87394.1 - 0.057 12.6 0.0 0.43 9.7 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) HEAT PF02985.17 EME87395.1 - 6.9e-46 150.2 26.4 0.0018 18.2 0.0 13.4 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EME87395.1 - 2.1e-35 120.8 6.8 2.1e-08 34.3 0.0 8.4 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 EME87395.1 - 7.1e-14 51.8 16.2 0.079 13.4 0.0 10.1 6 4 5 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EME87395.1 - 1.1e-11 44.9 2.6 0.0013 19.0 0.1 7.0 6 2 2 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EME87395.1 - 8.4e-08 30.9 8.1 0.00018 19.9 0.3 4.9 3 2 0 4 4 4 3 Adaptin N terminal region Arm PF00514.18 EME87395.1 - 1.5e-06 27.7 4.4 2.2 8.2 0.0 6.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EME87395.1 - 5.5e-06 25.9 1.4 0.29 10.4 0.0 5.0 3 2 1 4 4 4 2 CLASP N terminal DUF2435 PF10363.4 EME87395.1 - 0.004 17.0 3.4 3.6 7.5 0.1 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) RIX1 PF08167.7 EME87395.1 - 0.038 13.6 0.2 8.4 6.0 0.0 3.8 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 EME87395.1 - 0.12 10.6 1.7 0.92 7.7 0.1 2.8 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Ribosomal_S7e PF01251.13 EME87396.1 - 1.2e-80 269.4 0.2 1.4e-80 269.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Pkinase PF00069.20 EME87398.1 - 3.2e-59 200.1 0.0 4.5e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87398.1 - 3.1e-20 72.3 0.0 5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME87398.1 - 5.8e-07 28.7 0.0 1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME87398.1 - 1.7e-06 27.9 1.1 0.036 13.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EME87398.1 - 0.00041 19.4 0.1 0.00083 18.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EME87398.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PAS_9 PF13426.1 EME87398.1 - 0.033 14.5 0.0 0.57 10.5 0.0 3.0 3 1 0 3 3 3 0 PAS domain Seadorna_VP7 PF07387.6 EME87398.1 - 0.37 9.5 0.0 0.62 8.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_6 PF13516.1 EME87401.1 - 2.8e-11 42.2 9.6 0.15 12.2 0.0 8.7 11 0 0 11 11 11 2 Leucine Rich repeat F-box PF00646.28 EME87401.1 - 6.7e-09 35.1 0.3 2.9e-08 33.1 0.2 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME87401.1 - 8.8e-09 34.9 0.4 2.4e-08 33.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EME87401.1 - 1e-07 31.4 6.7 0.012 15.2 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME87401.1 - 6.3e-07 29.0 7.5 0.004 16.8 0.0 4.4 3 1 1 4 4 4 2 Leucine rich repeat PRANC PF09372.5 EME87401.1 - 0.0022 17.9 0.5 0.02 14.8 0.0 2.5 3 0 0 3 3 3 1 PRANC domain LRR_1 PF00560.28 EME87401.1 - 0.021 14.7 16.6 12 6.3 0.1 7.8 5 2 1 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EME87401.1 - 8.1 7.1 18.9 95 3.9 0.0 7.7 8 1 0 8 8 8 0 Leucine rich repeat DUF1295 PF06966.7 EME87403.1 - 7.9e-40 136.6 9.6 1.1e-39 136.1 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EME87403.1 - 0.024 14.8 0.7 0.078 13.1 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_23 PF13489.1 EME87404.1 - 1.7e-12 47.3 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME87404.1 - 1.2e-10 41.7 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87404.1 - 4e-08 32.9 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME87404.1 - 5e-08 33.3 0.0 1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME87404.1 - 0.00089 18.4 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MBOAT PF03062.14 EME87405.1 - 2e-30 106.0 30.4 1e-29 103.7 19.1 2.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family IU_nuc_hydro PF01156.14 EME87406.1 - 1.4e-85 287.3 0.0 1.6e-85 287.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glutaredoxin PF00462.19 EME87407.1 - 1.8e-14 53.4 0.0 3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.15 EME87407.1 - 0.01 15.4 1.7 1.4 8.4 0.0 2.5 2 1 1 3 3 3 2 DSBA-like thioredoxin domain Ribosomal_L6 PF00347.18 EME87408.1 - 6.5e-26 90.6 4.5 9.6e-13 48.4 1.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Acyl-CoA_dh_1 PF00441.19 EME87409.1 - 3.8e-27 95.2 1.3 5.7e-27 94.6 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME87409.1 - 4.6e-21 74.0 0.4 1e-20 72.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME87409.1 - 9.5e-20 71.2 0.0 3.2e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Mso1_C PF14477.1 EME87409.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Membrane-polarising domain of Mso1 Acyl-CoA_dh_2 PF08028.6 EME87409.1 - 0.0069 16.6 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain U79_P34 PF03064.11 EME87411.1 - 2.2 7.7 7.2 2.2 7.7 5.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Atrophin-1 PF03154.10 EME87411.1 - 8.1 4.4 6.4 8.7 4.3 4.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family RNA_lig_T4_1 PF09511.5 EME87413.1 - 2.2e-76 256.2 0.0 3.5e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EME87413.1 - 1e-72 244.4 0.0 2e-72 243.4 0.0 1.5 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EME87413.1 - 4e-51 173.2 0.0 7.3e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EME87413.1 - 0.023 15.5 0.2 0.27 12.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EME87413.1 - 0.028 14.3 0.5 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 EME87414.1 - 2.7e-84 283.3 22.5 3.1e-84 283.1 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87414.1 - 5.8e-26 91.0 33.5 5.1e-24 84.6 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME87414.1 - 0.00016 20.0 0.2 0.00016 20.0 0.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) USP8_interact PF08941.5 EME87414.1 - 0.22 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 USP8 interacting ADH_N PF08240.7 EME87415.1 - 6.8e-32 109.4 0.1 6.8e-32 109.4 0.1 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME87415.1 - 7.6e-26 90.1 0.1 1.3e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME87415.1 - 8.2e-05 23.4 0.0 0.00017 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EME87415.1 - 0.0055 17.2 0.0 0.017 15.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EME87415.1 - 0.0078 15.3 0.2 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PBCV_basic_adap PF08789.5 EME87415.1 - 1.2 8.7 3.4 0.97 9.1 0.4 2.1 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain adh_short PF00106.20 EME87416.1 - 2.9e-27 95.6 7.9 4e-27 95.1 5.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME87416.1 - 2.2e-26 93.0 2.2 2.7e-26 92.8 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME87416.1 - 1e-12 48.0 5.2 2e-12 47.1 3.6 1.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EME87416.1 - 0.0038 15.9 0.6 0.0053 15.5 0.4 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sulf_coat_C PF12193.3 EME87416.1 - 0.0076 16.0 0.1 0.022 14.5 0.1 1.8 1 0 0 1 1 1 1 Sulfolobus virus coat protein C terminal Polysacc_synt_2 PF02719.10 EME87416.1 - 0.022 13.6 0.3 0.022 13.6 0.2 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EME87416.1 - 0.028 13.8 1.1 0.046 13.1 0.7 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACT PF01842.20 EME87416.1 - 0.069 12.6 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 ACT domain F_bP_aldolase PF01116.15 EME87417.1 - 9.9e-80 267.6 0.0 1.1e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II STAS PF01740.16 EME87417.1 - 0.037 13.4 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 STAS domain GHL6 PF14871.1 EME87417.1 - 0.048 13.6 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Dak1 PF02733.12 EME87418.1 - 6.7e-111 369.9 0.0 9.7e-111 369.4 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EME87418.1 - 5.4e-25 88.0 12.8 7.6e-24 84.3 1.9 2.7 2 1 1 3 3 3 2 DAK2 domain adh_short_C2 PF13561.1 EME87419.1 - 2e-31 109.6 0.0 2.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME87419.1 - 3.9e-27 95.1 0.0 4.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME87419.1 - 2.8e-09 36.8 0.0 5.8e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME87419.1 - 1.2e-06 28.1 0.1 1.5e-06 27.8 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EME87419.1 - 0.0016 18.1 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EME87419.1 - 0.0073 16.1 1.1 0.013 15.3 0.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EME87419.1 - 0.0091 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EME87419.1 - 0.028 13.9 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.14 EME87419.1 - 0.061 12.0 0.2 0.087 11.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IlvN PF07991.7 EME87419.1 - 0.081 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EME87419.1 - 0.093 13.1 0.1 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.3 EME87420.1 - 1.9e-20 72.8 0.1 2.4e-19 69.2 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EME87420.1 - 0.035 12.9 0.2 0.062 12.1 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EME87421.1 - 2.1e-27 96.4 0.0 2.8e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME87421.1 - 1.5e-24 86.7 0.1 1.9e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME87421.1 - 2.9e-07 30.3 0.1 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME87421.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME87422.1 - 3.1e-25 89.3 0.0 4.3e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME87422.1 - 8.7e-25 87.5 0.1 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME87422.1 - 2.3e-10 40.4 0.1 3.7e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME87422.1 - 0.00062 19.2 0.0 0.00091 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME87422.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EME87423.1 - 1.1e-39 136.1 30.5 1.1e-39 136.1 21.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily PAF-AH_p_II PF03403.8 EME87424.1 - 7.1e-52 175.9 0.0 8.2e-26 90.1 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EME87424.1 - 1.7e-11 44.1 0.1 8.6e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME87424.1 - 2e-08 34.3 0.0 8.8e-08 32.3 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME87424.1 - 2.4e-05 23.3 0.0 0.00066 18.6 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME87424.1 - 0.00061 18.6 0.5 0.0017 17.2 0.0 1.9 3 0 0 3 3 3 1 Chlorophyllase DLH PF01738.13 EME87424.1 - 0.0094 15.2 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family RRM_1 PF00076.17 EME87425.1 - 2.1e-11 43.2 0.8 1e-06 28.2 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME87425.1 - 5.5e-11 42.2 0.1 3.5e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME87425.1 - 1.1e-05 25.1 0.1 0.0043 16.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME87425.1 - 0.0061 16.3 0.7 0.84 9.5 0.4 2.9 2 0 0 2 2 2 1 RNA binding motif Arginase PF00491.16 EME87426.1 - 3.3e-75 252.9 0.3 4.1e-75 252.6 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EME87426.1 - 0.15 12.2 0.4 0.25 11.5 0.3 1.3 1 0 0 1 1 1 0 UPF0489 domain Cyt-b5 PF00173.23 EME87427.1 - 2.5e-11 43.2 0.1 3.2e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 EME87429.1 - 2.1e-60 200.2 0.0 7.9e-18 63.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME87429.1 - 3.4e-42 142.2 0.0 1.1e-12 47.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME87429.1 - 9.6e-26 89.4 0.1 1.7e-09 37.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EME87430.1 - 0.0016 18.4 7.8 0.0016 18.4 5.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EME87430.1 - 0.0029 17.3 7.5 0.0068 16.2 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.15 EME87430.1 - 1.1 8.7 5.7 2.9 7.4 3.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 EME87430.1 - 2.9 7.6 12.2 0.52 10.0 5.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.2 EME87431.1 - 6.1e-16 58.9 4.5 1.6e-14 54.3 3.2 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME87431.1 - 4.9e-09 36.0 0.0 9.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME87431.1 - 7.4e-06 25.7 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family OB_NTP_bind PF07717.11 EME87432.1 - 2.4e-24 85.3 0.0 5e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EME87432.1 - 1.9e-20 72.7 0.3 5.3e-20 71.3 0.2 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EME87432.1 - 5.2e-12 45.4 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME87432.1 - 2.1e-05 24.6 0.0 6.9e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EME87432.1 - 0.00029 20.3 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.1 EME87432.1 - 0.0029 17.2 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EME87432.1 - 0.012 14.5 0.0 0.045 12.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EME87432.1 - 0.018 14.4 0.1 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EME87432.1 - 0.057 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EME87432.1 - 0.069 13.0 0.2 3.2 7.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME87432.1 - 0.076 13.3 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EME87432.1 - 0.1 11.6 0.1 0.3 10.1 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EME87432.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase CUE PF02845.11 EME87433.1 - 1.6e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain S100PBPR PF15427.1 EME87434.1 - 0.027 13.5 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 S100P-binding protein DUF4647 PF15504.1 EME87435.1 - 0.013 14.3 2.2 0.014 14.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) FancD2 PF14631.1 EME87435.1 - 0.015 12.4 1.0 0.018 12.1 0.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Peptidase_S49_N PF08496.5 EME87435.1 - 0.17 11.6 2.9 0.33 10.7 2.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.20 EME87436.1 - 8.7e-57 192.2 0.1 5.3e-40 137.2 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME87436.1 - 1.2e-25 90.0 0.2 1.3e-20 73.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EME87436.1 - 0.00021 20.4 0.0 0.00065 18.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME87436.1 - 0.00022 21.0 0.9 0.029 14.0 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME87436.1 - 0.00069 18.6 0.0 0.0017 17.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EME87436.1 - 0.009 15.3 0.5 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase_C PF00433.19 EME87436.1 - 0.011 16.1 0.1 0.034 14.6 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain SpoIIIAH PF12685.2 EME87436.1 - 0.012 15.1 0.1 0.026 13.9 0.1 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein Pox_ser-thr_kin PF05445.6 EME87436.1 - 0.057 12.2 0.1 0.097 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EME87436.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DNA_RNApol_7kD PF03604.8 EME87437.1 - 8.6e-17 60.3 6.3 1.1e-16 59.9 4.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EME87437.1 - 0.0011 18.6 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EME87437.1 - 0.016 14.9 0.3 0.022 14.5 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 EME87437.1 - 0.028 13.8 2.8 0.044 13.2 2.0 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2318 PF10080.4 EME87437.1 - 0.075 12.8 0.3 0.095 12.4 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_1 PF00130.17 EME87437.1 - 0.081 12.6 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2082 PF09855.4 EME87437.1 - 0.11 12.3 0.4 0.11 12.3 0.3 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Prok-RING_1 PF14446.1 EME87437.1 - 0.18 11.5 1.4 0.25 11.1 1.0 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_recom PF13408.1 EME87437.1 - 0.53 10.5 3.4 8.7 6.6 0.7 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Fe_hyd_lg_C PF02906.9 EME87438.1 - 1.7e-65 221.1 0.0 3.2e-65 220.2 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain UQ_con PF00179.21 EME87439.1 - 4.5e-32 110.3 0.0 4.8e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME87439.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B SIR2 PF02146.12 EME87441.1 - 1.6e-57 194.1 0.0 2.5e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EME87441.1 - 5e-05 22.9 0.0 9.8e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EME87441.1 - 0.001 18.8 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF822 PF05687.8 EME87441.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Ribosomal_L34e PF01199.13 EME87441.1 - 0.041 14.1 1.0 0.08 13.1 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein L34e RNase_PH PF01138.16 EME87442.1 - 1e-15 58.2 0.0 2.1e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 TMF_TATA_bd PF12325.3 EME87445.1 - 7.6e-34 116.0 11.3 7.6e-34 116.0 7.8 6.4 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EME87445.1 - 8.3e-17 60.7 18.2 8.3e-17 60.7 12.6 9.1 5 3 3 8 8 8 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EME87445.1 - 5.9e-05 22.7 6.0 5.9e-05 22.7 4.1 5.7 2 1 2 5 5 5 2 IncA protein DUF4200 PF13863.1 EME87445.1 - 0.00094 19.1 15.9 0.00094 19.1 11.0 7.6 3 3 4 8 8 8 1 Domain of unknown function (DUF4200) Mod_r PF07200.8 EME87446.1 - 1.8e-06 27.9 7.4 2.7e-06 27.3 5.1 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PspA_IM30 PF04012.7 EME87446.1 - 0.00031 20.1 6.6 0.00039 19.8 4.6 1.1 1 0 0 1 1 1 1 PspA/IM30 family DNA_pol_A_exo1 PF01612.15 EME87449.1 - 0.011 15.2 1.1 0.07 12.6 0.1 2.3 3 0 0 3 3 3 0 3'-5' exonuclease Neuropep_like PF15161.1 EME87449.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Neuropeptide-like RNase_T PF00929.19 EME87449.1 - 0.25 11.5 1.2 0.46 10.7 0.1 1.8 2 0 0 2 2 2 0 Exonuclease Nbl1_Borealin_N PF10444.4 EME87450.1 - 3e-22 77.7 3.8 5.7e-22 76.8 2.6 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal MutL_C PF08676.6 EME87450.1 - 0.053 13.1 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 MutL C terminal dimerisation domain VWA_2 PF13519.1 EME87451.1 - 4.6e-13 49.6 0.3 6.8e-13 49.0 0.2 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EME87451.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EME87451.1 - 3.5e-05 23.6 0.2 7.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EME87451.1 - 0.0047 16.3 0.6 0.012 15.1 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Dynein_heavy PF03028.10 EME87451.1 - 0.084 10.8 0.0 0.084 10.8 0.0 1.3 2 0 0 2 2 2 0 Dynein heavy chain and region D6 of dynein motor DUF2405 PF10293.4 EME87451.1 - 0.36 10.5 2.2 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) Mito_carr PF00153.22 EME87452.1 - 1.6e-71 236.0 0.6 1.1e-24 85.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EME87452.1 - 2.7e-10 39.2 1.5 1.6e-05 24.4 0.0 5.3 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 EME87452.1 - 1.3e-09 38.0 0.4 2.1e-05 24.5 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EME87452.1 - 2.8e-08 32.4 2.0 3.6e-06 25.8 0.0 4.4 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 EME87452.1 - 1.3e-06 27.9 1.1 1.8 8.2 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EME87452.1 - 5.6e-05 22.2 0.7 0.0003 19.9 0.0 2.5 3 0 0 3 3 3 1 EF hand Mito_carr PF00153.22 EME87453.1 - 4e-46 154.6 1.6 1.6e-15 56.5 0.3 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein AA_permease_2 PF13520.1 EME87455.1 - 3.7e-42 144.3 41.4 4.5e-42 144.0 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease PMP1_2 PF08114.6 EME87456.1 - 1.6 8.2 5.2 0.33 10.4 0.2 2.3 2 0 0 2 2 2 0 ATPase proteolipid family Methyltransf_4 PF02390.12 EME87458.1 - 1.5e-51 174.2 0.0 1.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EME87458.1 - 0.0005 19.6 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME87458.1 - 0.00065 20.1 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87458.1 - 0.0027 18.2 0.0 0.0037 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME87458.1 - 0.0029 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME87458.1 - 0.003 17.2 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME87458.1 - 0.0056 17.0 0.0 0.041 14.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 EME87458.1 - 0.023 13.6 0.0 0.062 12.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 EME87458.1 - 0.039 14.4 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain TFIIA PF03153.8 EME87459.1 - 2 8.2 9.1 2.4 7.9 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PLA2_B PF01735.13 EME87460.1 - 5e-14 51.3 0.0 2.4e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Lysophospholipase catalytic domain HAD_2 PF13419.1 EME87461.1 - 1e-17 64.9 0.0 1.3e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME87461.1 - 2.2e-09 38.0 0.0 3.3e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME87461.1 - 2.6e-06 27.0 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EME87461.1 - 4.1e-06 27.1 0.0 6.8e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EME87461.1 - 0.0034 17.2 0.0 0.13 12.2 0.0 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase La PF05383.12 EME87463.1 - 9.3e-18 63.7 0.8 1.6e-17 63.0 0.5 1.4 1 0 0 1 1 1 1 La domain Bromo_TP PF07524.8 EME87464.1 - 2.3e-07 30.4 0.1 4.4e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated DUF1330 PF07045.6 EME87464.1 - 0.27 11.1 1.3 0.72 9.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1330) HhH-GPD PF00730.20 EME87465.1 - 7.3e-20 71.2 0.0 2e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EME87465.1 - 1.3e-08 34.0 0.0 5.3e-08 32.1 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif CAML PF14963.1 EME87465.1 - 0.45 9.8 3.3 0.18 11.1 0.3 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF1754 PF08555.5 EME87466.1 - 2.1e-15 57.0 21.5 3.1e-15 56.5 14.9 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.5 EME87466.1 - 0.024 13.8 14.5 0.026 13.7 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2146 PF10220.4 EME87466.1 - 0.13 10.2 8.6 0.14 10.0 6.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF3347 PF11827.3 EME87466.1 - 0.43 10.5 10.4 0.54 10.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PIH1 PF08190.7 EME87466.1 - 0.92 8.8 8.9 1.1 8.5 6.1 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF913 PF06025.7 EME87466.1 - 1.4 7.6 5.4 1.7 7.3 3.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LZ_Tnp_IS66 PF13007.2 EME87466.1 - 2 9.1 14.8 0.12 12.9 6.0 1.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Hid1 PF12722.2 EME87466.1 - 2.4 5.7 8.7 2.6 5.5 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 EME87466.1 - 3.3 6.7 9.9 4 6.5 6.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2052 PF09747.4 EME87466.1 - 3.5 7.5 16.3 4.8 7.0 11.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Spore_coat_CotO PF14153.1 EME87466.1 - 4.8 6.5 16.7 6.2 6.2 11.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 EME87466.1 - 5.8 6.2 14.6 7.7 5.8 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ndc1_Nup PF09531.5 EME87466.1 - 6.5 5.0 7.4 7.6 4.8 5.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.12 EME87466.1 - 7 6.3 9.0 8.6 6.0 6.2 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 EME87466.1 - 7.4 6.3 12.3 8.8 6.1 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 STE2 PF02116.10 EME87467.1 - 3.5e-62 210.0 24.6 4e-62 209.8 17.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PufQ PF05398.6 EME87467.1 - 2.5 8.2 5.6 6.4 6.8 0.1 3.5 2 1 2 4 4 4 0 PufQ cytochrome subunit SP_C-Propep PF08999.5 EME87467.1 - 4.8 6.7 8.0 9.1 5.8 4.6 2.2 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide PI-PLC-X PF00388.14 EME87468.1 - 3e-59 198.5 0.0 1.1e-58 196.7 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EME87468.1 - 9.5e-38 128.8 0.1 2e-37 127.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EME87468.1 - 0.00039 20.3 0.5 0.00094 19.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Herpes_UL7 PF01677.11 EME87471.1 - 0.047 13.0 0.0 0.053 12.8 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL7 like adh_short PF00106.20 EME87472.1 - 2.6e-19 69.7 0.7 4.3e-19 69.0 0.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME87472.1 - 4.2e-10 39.8 0.0 5.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EME87472.1 - 6.8e-06 25.6 0.2 9.1e-06 25.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EME87472.1 - 6.9e-05 22.5 0.2 0.0018 17.9 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME87472.1 - 0.00034 20.6 0.0 0.00074 19.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME87472.1 - 0.0069 15.1 0.1 0.0086 14.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C2H2_4 PF13894.1 EME87473.1 - 1e-06 28.6 14.1 0.06 13.7 1.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Leu_zip PF15294.1 EME87473.1 - 0.0066 15.5 3.9 0.012 14.7 2.7 1.4 1 0 0 1 1 1 1 Leucine zipper zf-C2H2 PF00096.21 EME87473.1 - 0.01 16.1 16.7 0.032 14.5 1.4 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type DivIC PF04977.10 EME87473.1 - 2.1 7.8 6.6 0.85 9.1 2.8 1.7 1 1 1 2 2 2 0 Septum formation initiator zf-H2C2_2 PF13465.1 EME87473.1 - 3.5 8.0 15.6 20 5.7 1.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain bZIP_2 PF07716.10 EME87473.1 - 4.6 7.1 9.3 4.8 7.0 2.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper MMS19_N PF14500.1 EME87474.1 - 3.6e-77 259.1 0.0 1.2e-72 244.3 0.0 4.4 4 1 1 5 5 5 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EME87474.1 - 8.4e-64 215.8 1.7 2.5e-60 204.3 0.1 2.3 2 0 0 2 2 2 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EME87474.1 - 0.029 14.6 0.1 0.029 14.6 0.0 5.8 5 3 2 7 7 7 0 HEAT repeats Cnd1 PF12717.2 EME87474.1 - 0.046 13.5 0.4 60 3.4 0.1 3.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Corona_NS1 PF06145.6 EME87474.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 HEAT_EZ PF13513.1 EME87474.1 - 0.72 10.4 14.1 0.39 11.2 0.2 5.7 6 1 0 6 6 6 0 HEAT-like repeat SH3_1 PF00018.23 EME87475.1 - 9.5e-41 136.9 6.2 1.1e-13 50.3 0.2 4.2 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EME87475.1 - 5.4e-36 122.0 0.0 9e-36 121.3 0.0 1.3 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EME87475.1 - 2.2e-33 113.5 5.5 9.4e-13 47.5 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EME87475.1 - 2.1e-24 84.7 0.0 2.5e-08 33.2 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EME87475.1 - 0.0003 20.8 1.6 0.15 12.2 0.2 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain Sugar_tr PF00083.19 EME87476.1 - 6.9e-73 245.7 25.5 1.7e-38 132.3 10.3 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EME87476.1 - 1.7e-17 63.1 46.3 3.9e-10 38.9 7.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 EME87476.1 - 0.21 11.0 1.7 0.56 9.6 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) THF_DHG_CYH PF00763.18 EME87477.1 - 1.9e-16 60.1 0.0 2.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EME87477.1 - 1.6e-14 53.3 0.0 6.8e-10 38.2 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EME87477.1 - 0.054 13.5 0.0 10 6.2 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase SBP_bac_5 PF00496.17 EME87477.1 - 0.085 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2207 PF09972.4 EME87478.1 - 0.13 10.8 0.1 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 EME87479.1 - 8.4e-60 202.0 0.0 2.2e-37 128.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME87479.1 - 5e-28 97.8 0.0 2e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EME87479.1 - 1.3e-12 47.7 0.0 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EME87479.1 - 3.1e-07 29.6 0.0 3.7e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME87479.1 - 1.3e-06 28.3 0.0 0.00093 18.9 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 EME87479.1 - 0.00028 21.1 0.0 0.00088 19.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 EME87479.1 - 0.0037 16.3 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 EME87479.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EME87479.1 - 0.033 14.2 0.0 0.096 12.7 0.0 1.8 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EME87479.1 - 0.084 11.6 0.2 0.18 10.5 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.17 EME87479.1 - 0.12 11.6 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EME87479.1 - 2.4 6.8 0.0 3.9 6.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNA_pol_Rpb4 PF03874.11 EME87480.1 - 4.1e-21 75.1 0.9 5.6e-21 74.7 0.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 RhoGAP PF00620.22 EME87481.1 - 2.7e-38 130.9 0.0 5.6e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EME87481.1 - 3.4e-27 94.2 38.7 2.6e-12 46.6 4.1 5.0 5 0 0 5 5 5 4 LIM domain GPI-anchored PF10342.4 EME87482.1 - 2.9e-14 53.3 0.3 2.9e-14 53.3 0.2 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.5 EME87482.1 - 9.1 5.8 10.8 14 5.2 7.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 GPI-anchored PF10342.4 EME87483.1 - 1.4e-20 73.5 4.1 1.4e-20 73.5 2.8 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EME87483.1 - 0.0016 17.9 0.4 0.0034 16.9 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) Transglut_N PF00868.15 EME87483.1 - 0.15 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family KAR9 PF08580.5 EME87483.1 - 2.5 6.2 6.8 2.9 6.0 4.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Band_7 PF01145.20 EME87486.1 - 6.6e-30 104.3 1.7 7.6e-30 104.1 0.2 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EME87486.1 - 0.033 13.6 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Rotamase PF00639.16 EME87486.1 - 1 10.1 7.1 0.59 10.9 0.7 2.6 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF2622 PF11080.3 EME87487.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) Lectin_leg-like PF03388.8 EME87487.1 - 0.075 12.1 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Legume-like lectin family AzlD PF05437.7 EME87489.1 - 0.042 13.8 0.8 0.071 13.0 0.5 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) UPF0060 PF02694.10 EME87489.1 - 0.13 12.3 0.7 0.22 11.5 0.5 1.5 1 1 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family Glyoxalase PF00903.20 EME87490.1 - 3.1e-07 30.3 0.0 4.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME87490.1 - 5.7e-05 23.6 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain CENP-B_N PF04218.8 EME87490.1 - 0.02 14.2 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Abhydrolase_3 PF07859.8 EME87491.1 - 5.2e-09 35.9 0.1 6.2e-08 32.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EME87491.1 - 2e-07 31.1 1.9 6.4e-07 29.4 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME87491.1 - 2.7e-06 27.2 0.0 6e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EME87491.1 - 0.0015 18.8 0.1 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain DUF915 PF06028.6 EME87491.1 - 0.023 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 EME87491.1 - 0.027 13.6 0.0 5.5 6.1 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF2305 PF10230.4 EME87491.1 - 0.05 13.0 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF2920 PF11144.3 EME87491.1 - 0.057 12.4 0.0 4.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.15 EME87491.1 - 0.067 12.7 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EME87491.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EME87491.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Asp_Glu_race PF01177.17 EME87493.1 - 6.2e-22 78.5 0.1 7.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DAGK_cat PF00781.19 EME87493.1 - 0.22 10.9 1.0 18 4.7 0.2 2.6 3 1 0 3 3 3 0 Diacylglycerol kinase catalytic domain Ion_trans PF00520.26 EME87494.1 - 1.4e-104 347.6 97.3 1.1e-34 119.4 3.2 6.2 7 0 0 7 7 7 4 Ion transport protein EF-hand_1 PF00036.27 EME87494.1 - 0.00015 20.8 0.0 0.00042 19.4 0.0 1.9 1 0 0 1 1 1 1 EF hand PKD_channel PF08016.7 EME87494.1 - 0.00039 18.9 6.0 0.00039 18.9 4.1 6.6 5 1 1 6 6 6 3 Polycystin cation channel EF-hand_6 PF13405.1 EME87494.1 - 0.0023 17.6 0.0 0.011 15.5 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain JSRP PF15312.1 EME87494.1 - 0.056 13.4 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein EF-hand_7 PF13499.1 EME87494.1 - 0.069 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair SR-25 PF10500.4 EME87495.1 - 0.21 11.0 2.4 0.33 10.3 1.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein bZIP_C PF12498.3 EME87495.1 - 0.69 11.1 4.0 0.9 10.7 2.8 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal mRNA_triPase PF02940.10 EME87496.1 - 2.7e-43 148.2 0.3 3.5e-43 147.8 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 EME87497.1 - 8.7e-43 142.2 20.7 5.8e-10 38.8 0.0 9.5 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EME87497.1 - 3.7e-21 75.1 1.9 2.4e-11 43.7 0.0 4.8 3 1 3 6 6 6 4 HEAT repeats HEAT PF02985.17 EME87497.1 - 2.8e-06 26.9 1.6 5.8 7.2 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EME87497.1 - 4e-05 23.9 0.8 0.07 13.6 0.0 4.5 5 1 0 5 5 5 1 HEAT-like repeat HEAT_PBS PF03130.11 EME87497.1 - 0.019 15.4 0.5 8.6 7.1 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat ERAP1_C PF11838.3 EME87497.1 - 0.054 12.7 0.1 0.43 9.7 0.0 2.3 2 0 0 2 2 2 0 ERAP1-like C-terminal domain RRM_1 PF00076.17 EME87498.1 - 1.2e-20 72.8 0.0 1.7e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME87498.1 - 4e-16 58.7 0.0 5.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME87498.1 - 3e-13 49.3 0.0 4.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.3 EME87499.1 - 1.4e-81 273.2 0.0 2.2e-81 272.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Cu-oxidase_3 PF07732.10 EME87500.1 - 1.1e-31 108.9 1.0 2.1e-29 101.6 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME87500.1 - 3.5e-28 97.8 1.3 6.6e-26 90.4 0.0 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EME87500.1 - 7.4e-14 51.9 0.0 3.6e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EME87500.1 - 0.098 12.5 0.0 1.6 8.7 0.0 2.6 2 1 0 2 2 2 0 Cupredoxin-like domain Gifsy-2 PF13856.1 EME87500.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage FAA_hydrolase PF01557.13 EME87501.1 - 2.2e-44 151.4 0.0 2.9e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EME87501.1 - 7.3e-23 80.6 0.0 6e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal PIG-S PF10510.4 EME87502.1 - 2.2e-142 475.3 2.4 2.6e-142 475.1 1.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein F-box PF00646.28 EME87504.1 - 0.026 14.2 0.2 1.5 8.5 0.0 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EME87504.1 - 0.045 13.4 0.0 0.53 10.0 0.0 2.8 2 1 0 2 2 2 0 F-box-like Cwf_Cwc_15 PF04889.7 EME87504.1 - 1.7 8.3 13.7 0.3 10.7 6.7 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EME87504.1 - 1.9 7.6 18.1 2.9 7.0 12.6 1.3 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 EME87504.1 - 2.9 7.2 12.0 4.3 6.6 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EME87504.1 - 5.8 4.8 13.5 8.4 4.2 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EME87504.1 - 6.2 4.6 22.8 11 3.8 15.8 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EME87504.1 - 7.4 4.9 18.4 11 4.3 12.7 1.1 1 0 0 1 1 1 0 Daxx Family CTP_transf_2 PF01467.21 EME87506.1 - 0.1 12.6 0.0 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylyltransferase WD40 PF00400.27 EME87507.1 - 1.5e-20 72.1 5.4 2e-07 30.6 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 EME87508.1 - 4.1e-09 36.3 0.0 8.4e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME87508.1 - 1.3e-06 28.4 0.0 1.8e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EME87508.1 - 4.7e-05 22.9 1.1 0.00015 21.2 0.0 2.3 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EME87508.1 - 0.0014 17.8 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EME87508.1 - 0.024 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Filament PF00038.16 EME87509.1 - 0.0017 17.8 4.3 0.0017 17.8 3.0 2.1 3 0 0 3 3 3 1 Intermediate filament protein Seryl_tRNA_N PF02403.17 EME87509.1 - 0.0051 16.7 6.4 0.0051 16.7 4.4 3.1 3 1 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.7 EME87509.1 - 0.18 11.6 6.6 0.074 12.8 1.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Allexi_40kDa PF05549.6 EME87509.1 - 0.23 10.7 1.6 0.5 9.6 0.4 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein IFT57 PF10498.4 EME87509.1 - 0.25 10.0 6.6 0.042 12.5 2.0 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF641 PF04859.7 EME87509.1 - 0.47 10.2 5.4 12 5.6 0.9 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Spc24 PF08286.6 EME87509.1 - 2.7 7.6 6.5 0.58 9.8 1.5 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EME87509.1 - 4.6 7.1 12.8 1.2 9.0 5.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EME87509.1 - 5 6.6 12.4 0.26 10.8 3.7 2.4 3 0 0 3 3 3 0 IncA protein FlxA PF14282.1 EME87509.1 - 8.4 6.4 11.7 2.6 8.0 5.6 2.1 2 0 0 2 2 2 0 FlxA-like protein WD40 PF00400.27 EME87510.1 - 7.4e-21 73.2 35.2 3.8e-06 26.5 0.3 11.7 11 3 0 11 11 11 6 WD domain, G-beta repeat BBS2_N PF14781.1 EME87510.1 - 0.0023 17.5 0.0 1.6 8.3 0.0 3.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal PQQ_3 PF13570.1 EME87510.1 - 7.1 7.0 6.3 13 6.1 0.3 4.4 5 0 0 5 5 5 0 PQQ-like domain Tad PF13400.1 EME87511.1 - 0.21 11.6 3.7 0.43 10.6 2.6 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF4044 PF13253.1 EME87511.1 - 2.3 7.4 4.4 3.6 6.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) SMC_N PF02463.14 EME87512.1 - 1.1e-57 194.7 0.0 2.5e-56 190.3 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EME87512.1 - 2.4e-26 92.0 0.0 1.1e-25 89.9 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EME87512.1 - 3.3e-11 43.6 1.8 0.00018 21.5 0.1 3.4 3 0 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 EME87512.1 - 1.3e-08 34.4 12.1 0.1 11.7 1.2 4.4 4 0 0 4 4 4 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 EME87512.1 - 2.1e-08 33.5 0.0 4.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME87512.1 - 3.1e-07 30.9 32.4 3.1e-07 30.9 22.5 7.8 2 2 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EME87512.1 - 0.0015 18.4 0.0 0.007 16.2 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Spc7 PF08317.6 EME87512.1 - 0.42 9.2 99.3 0.0049 15.5 6.8 6.5 2 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.22 EME87512.1 - 0.54 10.5 0.0 0.54 10.5 0.0 6.1 3 2 1 4 4 4 0 ABC transporter Baculo_PEP_C PF04513.7 EME87512.1 - 0.75 9.6 23.9 0.95 9.2 0.0 6.2 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2838 PF10998.3 EME87513.1 - 1.7e-42 143.8 12.3 1.7e-42 143.8 8.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Val_tRNA-synt_C PF10458.4 EME87513.1 - 0.46 10.5 3.8 0.3 11.1 0.2 2.3 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm GMC_oxred_C PF05199.8 EME87514.1 - 2.8e-17 63.3 0.0 4.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EME87514.1 - 1.6e-15 57.0 0.0 2.4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Nnf1 PF03980.9 EME87515.1 - 7.3e-24 83.8 2.9 7.3e-24 83.8 2.0 2.2 1 1 1 2 2 2 1 Nnf1 Med30 PF11315.3 EME87515.1 - 0.0098 16.0 2.4 0.019 15.1 0.9 1.9 1 1 0 2 2 2 1 Mediator complex subunit 30 DUF892 PF05974.7 EME87515.1 - 0.079 12.7 1.1 0.15 11.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) BLOC1_2 PF10046.4 EME87515.1 - 0.082 13.0 2.1 0.56 10.3 0.5 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 EME87515.1 - 0.096 12.4 2.3 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EME87515.1 - 0.12 12.8 2.6 0.25 11.7 0.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DASH_Duo1 PF08651.5 EME87515.1 - 0.14 11.7 3.9 3.8 7.1 0.0 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 AAA_13 PF13166.1 EME87515.1 - 0.17 10.3 3.2 0.21 9.9 2.2 1.0 1 0 0 1 1 1 0 AAA domain GP41 PF00517.12 EME87515.1 - 0.2 11.2 0.9 0.34 10.4 0.3 1.6 2 0 0 2 2 2 0 Retroviral envelope protein Cytochrom_B562 PF07361.6 EME87515.1 - 0.21 12.0 2.8 4.9 7.6 0.7 2.3 2 0 0 2 2 2 0 Cytochrome b562 TBPIP PF07106.8 EME87515.1 - 0.23 10.9 5.4 0.27 10.7 1.6 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ISG65-75 PF11727.3 EME87515.1 - 4.1 6.3 6.8 0.65 8.9 1.5 1.8 2 0 0 2 2 2 0 Invariant surface glycoprotein IncA PF04156.9 EME87515.1 - 9.7 5.7 7.5 0.57 9.7 1.5 1.6 2 0 0 2 2 2 0 IncA protein SSrecog PF03531.9 EME87516.1 - 8.9e-74 247.5 0.5 2.6e-72 242.7 0.3 2.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EME87516.1 - 1.1e-28 99.0 0.5 2.5e-27 94.6 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 EME87516.1 - 0.12 11.5 0.1 0.12 11.5 0.1 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Acetyltransf_1 PF00583.19 EME87517.1 - 3.7e-15 55.7 0.0 5.5e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME87517.1 - 3.8e-07 29.7 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EME87517.1 - 3.3e-05 23.8 0.1 5.4e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME87517.1 - 6.6e-05 23.0 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME87517.1 - 0.0019 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME87517.1 - 0.0047 16.8 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME87517.1 - 0.0059 16.4 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EME87517.1 - 0.0095 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3591 PF12157.3 EME87519.1 - 2.6e-173 576.6 0.0 3.6e-173 576.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EME87519.1 - 0.0062 16.1 1.0 0.017 14.7 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EME87519.1 - 0.012 15.4 0.9 0.026 14.4 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Reo_sigmaC PF04582.7 EME87520.1 - 0.0068 15.6 0.1 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein SlyX PF04102.7 EME87520.1 - 0.034 14.5 9.3 0.87 10.0 0.5 3.6 3 0 0 3 3 3 0 SlyX MscS_porin PF12795.2 EME87520.1 - 0.052 12.8 1.9 0.16 11.2 1.3 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EME87520.1 - 0.11 11.1 0.2 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 EME87520.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BicD PF09730.4 EME87520.1 - 0.15 10.3 0.7 0.22 9.8 0.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D NPV_P10 PF05531.7 EME87520.1 - 0.2 11.9 0.1 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EME87520.1 - 0.41 10.5 0.7 7 6.6 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RNase_T PF00929.19 EME87521.1 - 1.7e-24 86.9 0.0 2.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease PEP-utilisers_N PF05524.8 EME87522.1 - 0.11 12.3 1.2 0.19 11.5 0.8 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal UQ_con PF00179.21 EME87523.1 - 3.6e-44 149.5 0.9 1.8e-29 101.9 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EME87523.1 - 3.9e-07 29.8 0.0 1.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EME87523.1 - 0.0055 16.5 0.2 2.6 7.9 0.1 2.6 2 1 0 2 2 2 2 RWD domain UEV PF05743.8 EME87523.1 - 0.0063 16.1 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 UEV domain Sybindin PF04099.7 EME87524.1 - 1.4e-45 154.5 0.0 1.7e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EME87524.1 - 8.1e-07 28.9 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2312 PF10073.4 EME87525.1 - 0.071 12.4 0.1 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Peptidase_S8 PF00082.17 EME87526.1 - 4.6e-41 140.8 16.9 6.4e-41 140.3 11.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EME87526.1 - 0.03 14.8 0.2 0.085 13.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase inhibitor I9 Pkinase PF00069.20 EME87527.1 - 1.9e-67 227.1 0.0 2.7e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87527.1 - 3.2e-33 114.8 0.0 7.3e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EME87527.1 - 1.6e-12 47.3 0.8 3.6e-10 39.8 0.1 2.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EME87527.1 - 0.0005 19.1 0.0 0.0015 17.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME87527.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EME87527.1 - 0.026 14.2 1.5 1.5 8.4 0.0 3.4 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pcc1 PF09341.5 EME87529.1 - 1.2e-22 79.7 0.1 1.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 AA_permease_2 PF13520.1 EME87530.1 - 8.3e-55 186.0 50.1 1.1e-54 185.6 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME87530.1 - 2.8e-15 55.6 36.8 4.7e-15 54.8 25.5 1.3 1 1 0 1 1 1 1 Amino acid permease Lipoprotein_X PF03305.8 EME87531.1 - 0.16 11.3 1.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein Tyrosinase PF00264.15 EME87533.1 - 1e-40 140.2 0.0 1.4e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_redox PF00070.22 EME87534.1 - 2e-11 44.1 4.1 2.5e-10 40.5 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME87534.1 - 1.2e-10 41.6 0.3 4.7e-10 39.6 0.2 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME87534.1 - 0.00032 20.5 3.9 1.7 8.3 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EME87534.1 - 0.00075 18.5 0.0 0.0019 17.1 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) ELFV_dehydrog PF00208.16 EME87534.1 - 0.01 15.4 2.5 0.074 12.6 0.4 2.3 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Thi4 PF01946.12 EME87534.1 - 0.026 13.6 0.3 1.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Thi4 family GYD PF08734.6 EME87534.1 - 0.099 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 GYD domain Trp_halogenase PF04820.9 EME87534.1 - 0.12 11.0 1.5 2.5 6.6 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Mito_carr PF00153.22 EME87536.1 - 1.4e-57 191.3 4.0 1.2e-19 69.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dynamin_M PF01031.15 EME87537.1 - 9.1e-114 379.2 0.0 2.2e-113 377.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EME87537.1 - 9e-56 188.2 1.1 1.5e-55 187.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EME87537.1 - 1.9e-31 107.7 1.6 4.9e-31 106.4 1.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EME87537.1 - 0.00038 20.3 0.0 0.0053 16.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME87537.1 - 0.036 14.5 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein LtrA PF06772.6 EME87538.1 - 9.6e-10 37.8 13.9 9.6e-10 37.8 9.6 3.0 3 0 0 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) Pyridoxal_deC PF00282.14 EME87540.1 - 2.8e-21 75.4 0.0 4.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EME87540.1 - 0.00037 19.3 0.0 0.00071 18.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME87540.1 - 0.003 16.6 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.6 EME87540.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) cobW PF02492.14 EME87541.1 - 2.8e-33 114.8 0.0 3.4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EME87541.1 - 6.6e-06 25.0 0.5 6.9e-05 21.7 0.3 1.9 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EME87541.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EME87541.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EME87541.1 - 0.014 15.7 0.0 0.02 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EME87541.1 - 0.015 16.0 0.1 0.027 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME87541.1 - 0.04 13.9 0.1 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EME87541.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.18 EME87541.1 - 0.064 12.6 0.1 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EME87541.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EME87541.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 EME87541.1 - 0.12 11.7 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase NACHT PF05729.7 EME87541.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.7 EME87541.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Parvo_NS1 PF01057.12 EME87541.1 - 0.17 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 BRO1 PF03097.13 EME87542.1 - 6.6e-05 21.8 0.0 9.8e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain RTA1 PF04479.8 EME87543.1 - 6e-41 140.3 4.3 1e-40 139.6 3.0 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF3272 PF11676.3 EME87543.1 - 0.097 12.6 0.5 0.097 12.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) EHN PF06441.7 EME87546.1 - 5e-31 106.9 1.0 1.8e-30 105.1 0.0 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EME87546.1 - 5.1e-12 46.1 0.0 7.4e-12 45.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME87546.1 - 1.8e-09 37.4 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PXA PF02194.10 EME87547.1 - 2.6e-45 154.2 0.3 1.7e-44 151.5 0.0 2.5 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EME87547.1 - 4.2e-26 91.2 0.6 4.4e-25 87.9 0.0 3.0 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EME87547.1 - 7.1e-23 80.5 0.5 2.9e-22 78.5 0.2 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EME87547.1 - 2.1e-11 43.9 0.1 6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2360 PF10152.4 EME87547.1 - 0.03 14.5 0.9 2.8 8.2 0.0 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) V_ATPase_I PF01496.14 EME87547.1 - 0.24 9.1 2.1 0.67 7.7 0.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fungal_trans_2 PF11951.3 EME87548.1 - 1.3e-09 37.1 1.5 1.9e-09 36.6 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME87548.1 - 8.4e-07 28.8 8.7 8.4e-07 28.8 6.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.3 EME87549.1 - 7e-124 413.2 1.5 8.1e-124 413.0 1.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NST1 PF13945.1 EME87549.1 - 0.074 13.1 3.4 0.32 11.0 0.5 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DRMBL PF07522.9 EME87550.1 - 1.1e-33 115.5 0.0 2e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EME87550.1 - 4.3e-11 42.7 0.0 9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MIP-T3 PF10243.4 EME87552.1 - 2.7 6.3 55.7 6.8 5.0 38.6 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Voltage_CLC PF00654.15 EME87553.1 - 1.4e-12 47.3 0.7 1.3e-10 40.8 0.1 2.2 1 1 1 2 2 2 2 Voltage gated chloride channel Choline_kinase PF01633.15 EME87554.1 - 1.2e-47 162.1 0.0 2.2e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EME87554.1 - 1.1e-13 51.4 0.2 2.4e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EME87554.1 - 8.6e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EME87554.1 - 0.045 12.3 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CHCH PF06747.8 EME87556.1 - 3.9e-06 26.6 0.3 6.3e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EME87556.1 - 0.012 15.6 2.1 0.046 13.7 1.5 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EME87556.1 - 0.11 12.3 1.3 0.3 10.9 0.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EME87556.1 - 0.34 10.7 1.7 16 5.4 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) HLH PF00010.21 EME87557.1 - 5.6e-12 45.1 0.0 2.4e-11 43.1 0.0 2.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 EME87557.1 - 2.1 6.5 15.8 3.3 5.8 10.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Got1 PF04178.7 EME87559.1 - 3e-33 114.4 13.6 3.7e-33 114.1 9.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2632 PF10943.3 EME87559.1 - 0.79 9.1 8.2 1.1 8.7 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) TRI12 PF06609.8 EME87562.1 - 3e-08 32.3 2.7 3.8e-08 32.0 1.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME87562.1 - 0.13 10.9 6.7 2.3 6.8 3.0 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF418 PF04235.7 EME87562.1 - 0.2 11.3 2.1 0.54 9.9 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF418) TRI12 PF06609.8 EME87563.1 - 5e-16 58.0 1.5 5.9e-16 57.7 1.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Claudin_2 PF13903.1 EME87563.1 - 8 6.1 7.0 81 2.8 4.9 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1275 PF06912.6 EME87565.1 - 3.7e-34 117.7 16.9 4.4e-34 117.5 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3367 PF11847.3 EME87565.1 - 0.054 11.4 4.3 0.07 11.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) VirB8 PF04335.8 EME87565.1 - 0.22 11.0 3.0 3.5 7.1 0.2 2.2 2 0 0 2 2 2 0 VirB8 protein Herpes_US9 PF06072.6 EME87565.1 - 0.27 11.0 2.7 4.4 7.2 0.0 3.2 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Tetraspannin PF00335.15 EME87565.1 - 3.2 6.9 7.3 0.33 10.1 1.0 2.2 1 1 1 2 2 2 0 Tetraspanin family DUF1097 PF06496.6 EME87565.1 - 8.1 6.2 12.9 1.2 8.9 0.3 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1097) DUF3493 PF11998.3 EME87565.1 - 8.8 6.3 8.7 0.36 10.7 1.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) ADH_N PF08240.7 EME87567.1 - 1.3e-23 82.8 1.5 2.8e-23 81.7 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME87567.1 - 5.7e-20 71.1 0.9 1.1e-19 70.2 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EME87567.1 - 0.055 13.0 0.2 0.091 12.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Nup160 PF11715.3 EME87569.1 - 2.7e-76 256.8 0.0 3.9e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF3808 PF10300.4 EME87570.1 - 2.9e-136 454.7 0.2 3.5e-136 454.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EME87570.1 - 0.1 12.2 5.8 0.61 9.7 0.1 4.3 4 1 0 4 4 4 0 TPR repeat His_Phos_1 PF00300.17 EME87572.1 - 1.3e-25 90.3 0.0 2e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Hus1 PF04005.7 EME87572.1 - 0.16 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein WD40 PF00400.27 EME87573.1 - 7.9e-28 95.3 0.6 1.9e-06 27.5 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EME87573.1 - 0.018 13.3 0.0 0.032 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Peptidase_C36 PF05415.6 EME87573.1 - 0.13 12.1 0.1 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase Pkinase PF00069.20 EME87574.1 - 7.7e-68 228.4 0.0 1.2e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87574.1 - 3.9e-36 124.4 0.0 6.9e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME87574.1 - 1e-05 24.6 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME87574.1 - 0.00029 20.6 0.4 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EME87574.1 - 0.0076 15.1 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Complex1_LYR_1 PF13232.1 EME87575.1 - 1.7e-05 24.9 0.1 4.7e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EME87575.1 - 0.00017 21.2 2.2 0.00033 20.4 0.1 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Gryzun PF07919.7 EME87576.1 - 9.5e-65 218.9 0.0 1.3e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EME87576.1 - 5.2e-55 186.6 1.9 1.4e-50 172.1 0.7 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Cytochrom_B559 PF00283.14 EME87576.1 - 0.16 11.2 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Ank_2 PF12796.2 EME87577.1 - 2.2e-43 146.4 0.3 6e-21 74.5 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME87577.1 - 4e-41 138.6 7.8 8.7e-10 38.8 0.1 4.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME87577.1 - 3.3e-34 116.1 1.9 3.8e-09 36.4 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EME87577.1 - 5.4e-33 111.1 0.9 7.6e-06 25.4 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EME87577.1 - 1.2e-28 96.2 0.0 5.4e-05 23.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EME87577.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Sulfate_transp PF00916.15 EME87578.1 - 1e-38 132.9 5.3 2.2e-38 131.8 3.6 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EME87578.1 - 1.8e-11 43.5 0.0 4.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 EME87578.1 - 7.7e-11 41.6 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4481 PF14800.1 EME87578.1 - 4.9 5.9 5.7 1.2 7.9 0.1 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4481) PH_6 PF15406.1 EME87580.1 - 1.2e-26 92.9 0.2 1.2e-26 92.9 0.1 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EME87580.1 - 0.076 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 PH domain ubiquitin PF00240.18 EME87582.1 - 0.0074 15.6 0.0 0.025 13.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EME87582.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EME87582.1 - 0.027 14.6 1.8 0.077 13.1 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain MOZART1 PF12554.3 EME87584.1 - 1.9e-22 78.4 0.2 2.1e-22 78.2 0.2 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MFS_1 PF07690.11 EME87585.1 - 6.8e-34 117.1 59.3 1.6e-27 96.1 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME87585.1 - 3.1e-09 35.9 37.7 3.5e-05 22.5 10.6 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter PhaG_MnhG_YufB PF03334.9 EME87585.1 - 0.0029 17.6 1.1 0.0029 17.6 0.8 3.6 4 0 0 4 4 4 1 Na+/H+ antiporter subunit Asn_synthase PF00733.16 EME87587.1 - 6.6e-53 179.8 0.0 9.4e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EME87587.1 - 6.5e-07 29.1 0.0 3.2e-06 26.9 0.0 2.1 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EME87587.1 - 3.2e-06 27.1 0.0 7.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.13 EME87588.1 - 7.3e-29 99.8 0.0 1.6e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EME87588.1 - 2.7e-11 42.7 0.2 4.9e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 CUE domain DMA PF03474.9 EME87588.1 - 0.022 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif G0-G1_switch_2 PF15103.1 EME87588.1 - 0.33 11.2 3.3 0.36 11.0 0.3 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Mpv17_PMP22 PF04117.7 EME87589.1 - 1.2e-22 79.2 0.6 2.6e-22 78.2 0.4 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.14 EME87590.1 - 2.6e-150 500.2 1.8 3e-150 500.0 1.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.3 EME87590.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PrpR_N PF06506.6 EME87590.1 - 0.15 11.4 1.4 1.9 7.8 0.1 2.6 3 0 0 3 3 3 0 Propionate catabolism activator Abhydrolase_9 PF10081.4 EME87590.1 - 0.18 10.5 0.0 29 3.2 0.0 2.9 2 1 1 3 3 3 0 Alpha/beta-hydrolase family DNA_pol3_a_NI PF14480.1 EME87590.1 - 0.22 11.2 1.0 0.48 10.1 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I DSS1_SEM1 PF05160.8 EME87591.1 - 4.6e-20 71.1 10.1 8.6e-20 70.2 7.0 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family Sec7_N PF12783.2 EME87592.1 - 6e-26 90.8 0.0 1.5e-24 86.2 0.0 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EME87592.1 - 1.9e-05 24.0 0.2 0.00041 19.8 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Ribonuc_P_40 PF08584.6 EME87593.1 - 2.6e-52 177.6 0.0 3.6e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Rhabdo_glycop PF00974.13 EME87593.1 - 0.013 13.8 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Rad60-SLD_2 PF13881.1 EME87593.1 - 0.044 13.6 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like S1FA PF04689.8 EME87593.1 - 0.092 12.6 0.4 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DOCK-C2 PF14429.1 EME87594.1 - 6e-23 81.4 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EME87594.1 - 6e-13 48.4 0.0 1.4e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EME87594.1 - 0.026 13.9 0.0 0.064 12.6 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.1 EME87594.1 - 0.027 14.0 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain SH3_2 PF07653.12 EME87594.1 - 0.04 13.3 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Variant SH3 domain Glyco_hydro_2 PF00703.16 EME87595.1 - 1.7e-07 31.6 0.0 7.9e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EME87595.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Podoplanin PF05808.6 EME87596.1 - 2.3e-05 23.9 0.1 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Podoplanin DUF2062 PF09835.4 EME87596.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF1180 PF06679.7 EME87596.1 - 0.11 12.4 1.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HAMP PF00672.20 EME87596.1 - 0.14 12.3 0.4 0.31 11.2 0.3 1.6 1 0 0 1 1 1 0 HAMP domain SKG6 PF08693.5 EME87596.1 - 0.14 11.4 2.4 0.64 9.3 1.6 2.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 EME87596.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF2407_C PF13373.1 EME87596.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Rifin_STEVOR PF02009.11 EME87596.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family MtrF PF09472.5 EME87596.1 - 1.2 8.4 3.1 2.7 7.3 2.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Tubulin PF00091.20 EME87597.1 - 6.4e-73 245.1 0.0 8.7e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME87597.1 - 9.4e-43 145.2 0.2 1.9e-42 144.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME87597.1 - 8.6e-06 25.7 0.0 3.5e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME87597.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain GDPD PF03009.12 EME87598.1 - 5.4e-31 108.0 0.0 1.1e-23 84.0 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EME87598.1 - 0.53 10.5 3.2 6.9 6.9 2.2 2.5 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Tub_2 PF04525.7 EME87599.1 - 1.6e-24 86.3 0.7 2e-24 86.0 0.5 1.0 1 0 0 1 1 1 1 Tubby C 2 YabP PF07873.6 EME87599.1 - 0.026 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 YabP family CENP-B_dimeris PF09026.5 EME87600.1 - 0.28 11.4 4.3 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NAD_binding_5 PF07994.7 EME87602.1 - 1.9e-110 368.9 0.1 2.4e-110 368.6 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EME87602.1 - 6.4e-46 154.7 0.6 1.5e-45 153.5 0.4 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase AAA_2 PF07724.9 EME87603.1 - 1.2e-49 168.4 1.6 5.5e-48 163.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EME87603.1 - 5.1e-27 93.5 0.1 2.1e-26 91.6 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EME87603.1 - 5.8e-20 71.8 0.1 8.9e-10 38.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME87603.1 - 7e-13 48.4 0.2 9.8e-09 35.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME87603.1 - 6.3e-10 39.3 9.6 0.00026 21.0 0.0 5.2 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 EME87603.1 - 6.5e-10 39.2 0.6 0.0025 17.9 0.0 3.4 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EME87603.1 - 2.9e-08 33.3 0.9 6.7e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EME87603.1 - 6e-06 26.1 0.6 0.048 13.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EME87603.1 - 8.5e-06 25.5 0.0 0.036 13.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EME87603.1 - 2.2e-05 24.1 0.0 0.012 15.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EME87603.1 - 2.3e-05 24.1 6.1 0.13 11.9 0.0 4.3 3 2 0 3 3 3 2 Archaeal ATPase AAA_17 PF13207.1 EME87603.1 - 6.7e-05 23.6 5.1 0.14 12.9 0.0 4.0 4 1 0 4 4 3 2 AAA domain Mg_chelatase PF01078.16 EME87603.1 - 9e-05 21.7 0.1 0.61 9.2 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EME87603.1 - 0.00015 21.4 0.0 0.034 13.9 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 EME87603.1 - 0.00018 20.9 0.1 0.54 9.6 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein SRP54 PF00448.17 EME87603.1 - 0.00037 19.9 0.0 0.036 13.4 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EME87603.1 - 0.00072 19.7 0.0 0.56 10.4 0.0 3.0 2 1 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EME87603.1 - 0.001 18.2 0.0 0.36 9.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EME87603.1 - 0.001 19.0 1.4 1.7 8.5 0.0 4.1 3 1 1 4 4 4 1 AAA domain TrwB_AAD_bind PF10412.4 EME87603.1 - 0.0012 17.5 0.0 0.45 9.0 0.0 2.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EME87603.1 - 0.0023 18.2 3.0 0.95 9.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.10 EME87603.1 - 0.0023 17.7 0.8 1.6 8.5 0.0 3.6 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EME87603.1 - 0.0033 17.0 3.7 0.3 10.6 0.0 4.2 4 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 EME87603.1 - 0.0036 16.5 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EME87603.1 - 0.0044 16.4 0.0 0.7 9.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EME87603.1 - 0.005 17.1 7.8 0.44 10.8 0.1 3.5 4 1 0 4 4 2 2 AAA domain PduV-EutP PF10662.4 EME87603.1 - 0.0057 16.1 0.2 0.71 9.3 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EME87603.1 - 0.0059 16.2 0.3 0.59 9.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EME87603.1 - 0.018 15.5 0.1 1 9.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 EME87603.1 - 0.02 14.5 0.0 9.7 5.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EME87603.1 - 0.024 14.1 0.0 0.42 10.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 EME87603.1 - 0.027 13.3 1.4 1.1 8.1 0.1 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EME87603.1 - 0.054 13.3 0.0 4.5 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EME87603.1 - 0.07 12.6 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EME87603.1 - 0.14 11.8 2.2 1.6 8.3 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.1 EME87603.1 - 0.46 10.7 13.5 6.2 7.0 3.9 3.6 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 EME87603.1 - 0.66 9.7 5.3 24 4.6 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 IncA PF04156.9 EME87603.1 - 0.99 8.9 10.1 2.4 7.7 7.0 1.6 1 0 0 1 1 1 0 IncA protein AAA_10 PF12846.2 EME87603.1 - 1.5 8.1 6.2 0.42 9.9 0.1 3.0 3 2 0 3 3 2 0 AAA-like domain OEP PF02321.13 EME87603.1 - 3.8 7.0 13.5 8.3 5.9 9.4 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Seryl_tRNA_N PF02403.17 EME87603.1 - 4.3 7.4 16.9 13 5.8 9.5 3.0 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 EME87603.1 - 9.2 3.9 6.0 13 3.4 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EME87603.1 - 9.7 5.0 9.9 24 3.7 6.9 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EF1_GNE PF00736.14 EME87604.1 - 3.7e-31 106.6 2.6 8.1e-31 105.5 1.8 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EME87604.1 - 8.8e-14 51.3 9.9 8.8e-14 51.3 6.9 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 EME87604.1 - 0.0021 18.0 0.2 0.006 16.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EME87604.1 - 0.0053 17.2 0.1 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2730 PF10805.3 EME87604.1 - 0.081 12.6 0.2 0.35 10.6 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) MMgT PF10270.4 EME87605.1 - 2.1e-20 73.0 0.0 2.4e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.16 EME87606.1 - 2.4e-58 197.3 0.0 4.4e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME87606.1 - 3.3e-20 72.7 0.0 5.9e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EME87606.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 MutS family domain IV MFS_1 PF07690.11 EME87607.1 - 4.3e-41 140.8 38.0 4.3e-41 140.8 26.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Proteasom_Rpn13 PF04683.8 EME87608.1 - 4.4e-30 103.6 0.0 8e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 EME87609.1 - 8.3e-38 128.9 0.1 1.5e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Podoplanin PF05808.6 EME87610.1 - 0.0074 15.8 0.5 0.017 14.6 0.3 1.6 1 0 0 1 1 1 1 Podoplanin NUFIP2 PF15293.1 EME87610.1 - 0.25 9.9 2.7 0.37 9.4 1.8 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Cupin_8 PF13621.1 EME87611.1 - 4.1e-21 75.6 0.0 6.1e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain SKG6 PF08693.5 EME87611.1 - 0.0015 17.7 1.8 0.0031 16.7 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4328 PF14219.1 EME87611.1 - 0.0023 17.2 0.1 0.0043 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) Cupin_2 PF07883.6 EME87611.1 - 0.0088 15.5 0.0 0.024 14.1 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_4 PF08007.7 EME87611.1 - 0.031 13.5 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein DUF4234 PF14018.1 EME87611.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) FixQ PF05545.6 EME87611.1 - 0.13 11.9 1.5 0.24 11.0 1.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Beta-APP PF03494.8 EME87611.1 - 0.46 9.9 4.1 1.1 8.8 2.8 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Complex1_LYR PF05347.10 EME87612.1 - 8.7e-06 25.4 0.5 1.4e-05 24.7 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) PEMT PF04191.8 EME87613.1 - 1.5e-32 111.8 1.6 2.5e-32 111.1 1.1 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Aa_trans PF01490.13 EME87614.1 - 3.9e-17 61.8 27.6 3.9e-17 61.8 19.1 1.8 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein Sas10 PF09368.5 EME87616.1 - 2.8e-29 101.1 7.8 2.8e-29 101.1 5.4 3.1 2 1 1 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EME87616.1 - 1.8e-09 37.6 1.4 1.8e-09 37.6 1.0 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF3425 PF11905.3 EME87620.1 - 4.8e-22 78.3 0.2 6.1e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ADH_zinc_N PF00107.21 EME87622.1 - 8.3e-24 83.5 0.0 1.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME87622.1 - 8.2e-05 23.4 0.0 0.00095 20.0 0.0 2.4 2 1 1 3 3 3 1 Zinc-binding dehydrogenase PhoH PF02562.11 EME87622.1 - 0.0031 16.7 0.4 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein OsmC PF02566.14 EME87623.1 - 9.2e-15 54.6 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein CorA PF01544.13 EME87624.1 - 4.3e-17 62.0 0.1 5.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SpvB PF03534.8 EME87624.1 - 0.007 15.4 0.4 0.17 10.8 0.1 2.7 2 1 0 2 2 2 1 Salmonella virulence plasmid 65kDa B protein Ctr PF04145.10 EME87625.1 - 1.5e-35 122.3 0.2 1.8e-35 122.1 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.16 EME87625.1 - 0.024 14.3 0.4 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily Sugar_tr PF00083.19 EME87626.1 - 1.5e-81 274.2 23.5 1.9e-81 273.9 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87626.1 - 1.3e-26 93.1 35.1 6.7e-26 90.8 24.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EME87626.1 - 7.1e-08 31.1 1.6 1.2e-07 30.3 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Robl_LC7 PF03259.12 EME87627.1 - 1.2e-07 31.1 0.2 0.00067 19.1 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 EME87628.1 - 1.5e-17 63.4 1.2 2.3e-16 59.6 0.1 2.6 1 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation ApbA PF02558.11 EME87630.1 - 9.6e-24 83.5 0.0 1.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EME87630.1 - 4.5e-22 78.3 0.0 6.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal His_Phos_1 PF00300.17 EME87632.1 - 3.2e-29 102.0 0.2 3.9e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1348 PF07080.6 EME87633.1 - 1.3e-23 83.4 0.9 1.8e-23 82.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF2578 PF10843.3 EME87633.1 - 0.0048 16.6 0.1 0.0066 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Fungal_trans PF04082.13 EME87634.1 - 2.3e-18 66.0 0.0 3.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME87634.1 - 5.6e-06 26.1 9.6 1e-05 25.3 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3656 PF12392.3 EME87636.1 - 0.28 11.2 9.7 1.1 9.3 2.0 2.3 1 1 1 2 2 2 0 Collagenase Baculo_11_kDa PF06143.6 EME87636.1 - 0.45 9.8 2.9 0.76 9.1 2.0 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Abhydrolase_5 PF12695.2 EME87637.1 - 1.9e-05 24.4 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EME87637.1 - 0.014 13.8 0.1 0.33 9.4 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EME87637.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase SET PF00856.23 EME87638.1 - 2.1e-14 54.1 0.1 5.9e-13 49.4 0.1 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EME87638.1 - 0.1 12.9 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 SAF domain Ribosomal_S8 PF00410.14 EME87639.1 - 2.9e-22 78.8 0.0 2.6e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S8 DUF501 PF04417.7 EME87639.1 - 0.17 11.7 1.4 0.39 10.5 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3761 PF12587.3 EME87640.1 - 0.072 13.2 0.4 0.072 13.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) 2OG-FeII_Oxy_3 PF13640.1 EME87641.1 - 0.00058 20.3 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EME87641.1 - 0.0017 18.5 0.0 0.0042 17.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2457 PF10446.4 EME87644.1 - 5e-102 341.9 64.8 3.9e-70 236.8 28.6 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2457) DUF4520 PF15016.1 EME87646.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4520) Metallophos PF00149.23 EME87647.1 - 4.3e-41 140.5 0.2 5.7e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UbiA PF01040.13 EME87648.1 - 1.6e-27 96.3 18.2 2.4e-27 95.7 12.6 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 EME87650.1 - 3.3e-41 141.3 0.0 1.4e-36 126.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Biotin_lipoyl PF00364.17 EME87651.1 - 1.3e-19 69.5 0.1 3.8e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EME87651.1 - 0.00014 21.4 1.2 0.00032 20.2 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EME87651.1 - 0.00051 19.6 0.1 0.0048 16.5 0.0 2.5 3 0 0 3 3 3 1 Biotin-lipoyl like DUF1631 PF07793.6 EME87651.1 - 0.1 10.7 3.1 0.13 10.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PAS_9 PF13426.1 EME87653.1 - 8.3e-21 74.3 0.0 5.5e-17 62.0 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 EME87653.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.9 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.5 EME87653.1 - 0.018 15.0 0.5 14 5.7 0.0 3.5 3 1 1 4 4 4 0 PAS fold PQ-loop PF04193.9 EME87655.1 - 4.6e-27 93.3 17.6 1.4e-14 53.4 0.9 3.0 3 0 0 3 3 3 2 PQ loop repeat SirB PF04247.7 EME87655.1 - 0.013 15.1 0.6 0.026 14.2 0.4 1.5 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF4149 PF13664.1 EME87655.1 - 0.13 12.3 0.3 0.13 12.3 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) zf-HC5HC2H_2 PF13832.1 EME87656.1 - 3.1e-33 114.0 6.1 3.1e-33 114.0 4.2 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EME87656.1 - 8.1e-28 96.4 4.2 8.1e-28 96.4 2.9 2.7 2 1 0 2 2 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 EME87656.1 - 2.2e-20 73.5 0.0 7.3e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EME87656.1 - 1.4e-13 49.9 1.5 1.4e-13 49.9 1.0 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EME87656.1 - 3.2e-10 39.5 22.4 1.5e-08 34.2 6.8 2.6 2 0 0 2 2 2 2 PHD-finger Bromodomain PF00439.20 EME87656.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Bromodomain Mt_ATP-synt_B PF05405.9 EME87656.1 - 0.69 9.3 3.9 0.8 9.1 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-PHD-like PF15446.1 EME87656.1 - 1.9 7.7 11.6 0.047 12.9 2.1 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 EME87656.1 - 3.9 7.5 22.5 0.045 13.7 3.3 3.1 2 1 1 3 3 3 0 RING-like domain Abhydrolase_6 PF12697.2 EME87657.1 - 2e-17 63.8 0.0 2.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME87657.1 - 1.6e-15 56.7 0.0 2.5e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EME87657.1 - 1.2e-13 51.0 0.0 2e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME87657.1 - 2e-05 24.2 0.0 5.1e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EME87657.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PAF-AH_p_II PF03403.8 EME87657.1 - 0.081 11.2 0.1 0.46 8.7 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 EME87657.1 - 0.19 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Polysacc_synt_4 PF04669.8 EME87658.1 - 8.9e-25 87.1 1.9 5.2e-24 84.6 1.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Abhydrolase_5 PF12695.2 EME87659.1 - 2.2e-05 24.2 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EME87659.1 - 0.0039 15.7 0.1 0.0071 14.8 0.1 1.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EME87659.1 - 0.0044 16.4 0.1 0.38 10.1 0.0 2.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EME87659.1 - 0.0075 15.5 0.3 0.16 11.1 0.3 2.2 1 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 EME87659.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Esterase_phd PF10503.4 EME87659.1 - 0.045 12.9 0.1 0.072 12.3 0.1 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase zf-Sec23_Sec24 PF04810.10 EME87659.1 - 0.21 11.1 1.1 0.55 9.8 0.2 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Lactamase_B PF00753.22 EME87660.1 - 3.3e-15 56.2 4.7 4.7e-15 55.7 3.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME87660.1 - 0.12 11.9 1.3 0.17 11.4 0.9 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PDEase_II PF02112.10 EME87660.1 - 0.12 11.2 0.2 0.56 9.0 0.3 1.8 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II Acetyltransf_7 PF13508.1 EME87661.1 - 5.6e-11 42.4 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME87661.1 - 1.2e-10 41.2 0.0 2.6e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME87661.1 - 2.1e-08 34.3 0.0 3.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME87661.1 - 1.9e-06 27.7 0.3 5.4e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME87661.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.1 EME87661.1 - 0.084 12.8 0.7 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EME87662.1 - 1e-07 31.0 17.0 2.1e-05 23.4 4.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EME87663.1 - 4.6e-46 157.0 0.0 1.3e-45 155.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87663.1 - 2e-18 66.3 0.0 3.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME87663.1 - 0.00034 19.6 0.0 0.00058 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EME87663.1 - 0.0027 17.1 0.4 0.007 15.7 0.1 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 EME87663.1 - 0.0057 16.4 0.1 0.44 10.2 0.1 2.8 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EME87663.1 - 0.018 14.0 0.1 0.03 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L18p PF00861.17 EME87665.1 - 6e-42 142.6 1.0 7.2e-42 142.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EME87665.1 - 6.5e-34 116.3 8.8 6.5e-34 116.3 6.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EME87665.1 - 0.033 14.2 0.1 0.5 10.4 0.0 2.5 2 0 0 2 2 2 0 Threonine synthase N terminus Peptidase_S49_N PF08496.5 EME87665.1 - 7.6 6.3 12.9 1 9.1 4.8 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cytadhesin_P30 PF07271.6 EME87667.1 - 4.1 6.5 9.4 5.3 6.2 6.5 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Ank PF00023.25 EME87668.1 - 1.7e-11 43.3 0.0 2.4e-07 30.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EME87668.1 - 5.3e-11 42.7 0.0 5.7e-08 32.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME87668.1 - 3.1e-08 33.8 0.1 0.00016 22.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME87668.1 - 3.5e-07 29.8 0.1 0.0028 17.7 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EME87668.1 - 3.7e-07 30.1 0.0 1.6e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) KilA-N PF04383.8 EME87668.1 - 1.5e-05 24.5 0.1 6.7e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 KilA-N domain IGPS PF00218.16 EME87669.1 - 7.2e-94 313.5 0.2 1.8e-93 312.2 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EME87669.1 - 2e-50 170.9 0.0 3.4e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 EME87669.1 - 1.2e-46 158.7 0.2 4.4e-43 147.1 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 EME87669.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 BRCT PF00533.21 EME87670.1 - 5.8e-05 23.1 0.4 0.00016 21.7 0.3 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EME87670.1 - 0.0026 17.5 0.4 0.013 15.3 0.0 2.3 3 0 0 3 3 3 1 twin BRCT domain Retrotrans_gag PF03732.12 EME87670.1 - 0.03 14.3 0.1 0.084 12.9 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein WGR PF05406.10 EME87670.1 - 1.3 9.0 4.9 0.61 10.0 0.1 3.0 3 1 0 3 3 3 0 WGR domain NDUF_B7 PF05676.8 EME87671.1 - 3.3e-32 109.7 2.6 4e-32 109.4 1.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Nup188 PF10487.4 EME87672.1 - 2.3e-39 135.0 0.5 3.4e-37 127.9 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 NAD_binding_8 PF13450.1 EME87673.1 - 9.5e-11 41.5 0.9 2.1e-10 40.4 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EME87673.1 - 8e-09 35.0 0.0 0.002 17.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EME87673.1 - 1.9e-08 33.6 0.5 5.3e-06 25.5 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EME87673.1 - 7.3e-06 25.3 0.3 4.4e-05 22.7 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EME87673.1 - 1.1e-05 24.0 0.3 2e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EME87673.1 - 1.2e-05 24.3 0.7 2.1e-05 23.5 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EME87673.1 - 2.7e-05 24.3 0.3 0.0093 16.0 0.3 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME87673.1 - 0.00063 18.8 0.7 0.0011 18.1 0.5 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EME87673.1 - 0.00086 18.4 0.8 0.0013 17.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME87673.1 - 0.0014 18.5 0.4 0.0034 17.2 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME87673.1 - 0.0024 16.8 0.1 0.015 14.2 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EME87673.1 - 0.0053 15.6 0.5 0.008 15.0 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EME87673.1 - 0.017 14.9 0.4 0.16 11.7 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EME87673.1 - 0.02 15.2 0.7 0.19 12.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3651 PF12371.3 EME87673.1 - 0.036 14.0 0.3 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3651) Alg6_Alg8 PF03155.10 EME87674.1 - 1.2e-29 103.4 1.1 1.3e-29 103.3 0.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Glyco_transf_15 PF01793.11 EME87675.1 - 3.3e-90 302.3 0.8 3.8e-90 302.2 0.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase STT3 PF02516.9 EME87676.1 - 1e-128 430.3 36.2 4.6e-125 418.3 23.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit SUI1 PF01253.17 EME87677.1 - 1.8e-23 82.0 0.2 3.9e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EME87677.1 - 0.015 15.1 0.2 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV HrpA_pilin PF09589.5 EME87677.1 - 0.28 11.5 2.9 0.44 10.9 2.0 1.3 1 0 0 1 1 1 0 HrpA pilus formation protein DUF755 PF05501.6 EME87677.1 - 0.3 11.1 4.3 0.52 10.3 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Vps5 PF09325.5 EME87678.1 - 2.2e-82 275.8 3.8 3.1e-82 275.3 2.6 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EME87678.1 - 1.6e-24 85.8 0.0 3.7e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 PX domain Syntaxin-6_N PF09177.6 EME87678.1 - 0.42 11.0 2.9 2.6 8.5 1.0 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal F-box-like PF12937.2 EME87679.1 - 0.0024 17.5 0.3 1.1 9.0 0.1 2.5 2 0 0 2 2 2 2 F-box-like PIR PF00399.14 EME87680.1 - 0.0055 16.0 2.8 0.0055 16.0 1.9 3.0 3 0 0 3 3 3 1 Yeast PIR protein repeat Sugar_tr PF00083.19 EME87681.1 - 1.4e-21 76.6 27.2 1.8e-19 69.7 18.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Mito_carr PF00153.22 EME87682.1 - 2.4e-62 206.6 1.3 8.1e-20 70.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EME87684.1 - 9.8e-58 195.8 0.6 1.2e-57 195.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family IDO PF01231.13 EME87686.1 - 1.1e-166 554.4 0.0 1.3e-166 554.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EME87686.1 - 0.053 12.0 0.3 1.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) DUF2014 PF09427.5 EME87687.1 - 1.1e-80 270.5 0.7 1.8e-80 269.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EME87687.1 - 3.6e-16 58.5 0.5 8.8e-16 57.3 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2681 PF10883.3 EME87687.1 - 0.34 11.1 2.9 0.32 11.2 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Pex24p PF06398.6 EME87688.1 - 3.3e-86 289.3 0.1 4.3e-86 288.9 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EME87688.1 - 0.056 11.3 0.0 0.083 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PRT_C PF08372.5 EME87688.1 - 0.11 12.0 1.0 0.15 11.5 0.1 1.6 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal AA_permease PF00324.16 EME87689.1 - 2.4e-127 425.2 39.0 2.7e-127 425.0 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME87689.1 - 1.9e-36 125.5 41.3 2.5e-36 125.1 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 EME87689.1 - 1 9.8 4.9 13 6.3 1.5 2.8 2 0 0 2 2 2 0 Early E3 14.5 kDa protein DUF2422 PF10337.4 EME87691.1 - 7.4e-42 143.6 11.7 1.4e-39 136.1 8.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EME87691.1 - 0.00011 22.1 18.3 0.0011 18.8 1.6 3.6 2 1 1 3 3 3 2 Fusaric acid resistance protein-like ALMT PF11744.3 EME87691.1 - 2 6.9 10.3 6.4 5.3 0.0 3.4 2 2 1 3 3 3 0 Aluminium activated malate transporter GIY-YIG PF01541.19 EME87692.1 - 1.1e-10 41.7 0.9 4e-10 39.9 0.6 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain NUMOD1 PF07453.8 EME87692.1 - 0.00018 21.2 5.4 0.00059 19.5 0.4 2.9 2 0 0 2 2 2 1 NUMOD1 domain NUMOD3 PF07460.6 EME87692.1 - 0.003 17.4 11.5 0.024 14.5 0.2 3.1 3 0 0 3 3 3 2 NUMOD3 motif (2 copies) adh_short PF00106.20 EME87695.1 - 1.9e-17 63.6 0.0 2.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME87695.1 - 3.5e-08 33.5 0.0 4.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME87695.1 - 5.5e-06 26.1 0.0 8.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME87695.1 - 0.043 13.5 1.3 0.23 11.2 0.1 2.4 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HSP90 PF00183.13 EME87696.1 - 1.2e-254 845.6 36.6 1.4e-254 845.4 25.4 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EME87696.1 - 2.4e-11 43.3 0.0 4.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME87696.1 - 4.5e-11 42.5 0.2 4.5e-11 42.5 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EME87696.1 - 0.019 14.7 0.4 0.06 13.1 0.3 1.9 1 0 0 1 1 1 0 Tumour suppressor protein PVL_ORF50 PF07768.6 EME87696.1 - 6.3 6.8 18.2 0.34 10.9 4.1 3.0 2 1 0 2 2 2 0 PVL ORF-50-like family p450 PF00067.17 EME87698.1 - 5.2e-45 153.8 0.0 6.6e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF998 PF06197.8 EME87699.1 - 0.051 12.8 9.2 0.095 12.0 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) LigT_PEase PF02834.11 EME87699.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 LigT like Phosphoesterase Cytochrom_B561 PF03188.11 EME87699.1 - 0.19 11.5 5.4 0.32 10.8 3.7 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4234 PF14018.1 EME87699.1 - 0.19 11.4 1.0 0.47 10.2 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DUF2427 PF10348.4 EME87699.1 - 1.5 8.4 5.0 2.5 7.7 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) ATP-synt_DE_N PF02823.11 EME87700.1 - 5.1e-20 71.0 0.1 8.9e-20 70.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pkinase PF00069.20 EME87703.1 - 1.2e-55 188.5 0.0 1e-54 185.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME87703.1 - 7e-27 94.1 0.1 1.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DLH PF01738.13 EME87703.1 - 3.2e-16 59.2 0.0 5.3e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase_C PF00433.19 EME87703.1 - 0.00034 21.0 0.0 0.0009 19.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EME87703.1 - 0.0018 17.2 0.1 0.009 15.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EME87703.1 - 0.018 14.7 3.1 1 9.0 2.0 3.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family GATA PF00320.22 EME87705.1 - 8.2e-17 60.2 2.1 1.8e-16 59.1 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EME87705.1 - 1e-13 50.5 2.8 1.7e-13 49.8 1.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) F-box-like PF12937.2 EME87706.1 - 0.00061 19.4 0.1 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like GTP_EFTU PF00009.22 EME87707.1 - 8e-58 194.9 0.0 1.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME87707.1 - 1.3e-36 124.7 0.0 3.2e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EME87707.1 - 1.6e-15 56.9 2.2 1.6e-15 56.9 1.5 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EME87707.1 - 0.00048 20.0 0.4 0.0015 18.4 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EME87707.1 - 0.0013 18.2 0.7 0.0013 18.2 0.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 AAA PF00004.24 EME87708.1 - 4.3e-19 69.0 0.0 1e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EME87708.1 - 3.2e-07 30.1 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 EME87708.1 - 0.00013 22.7 0.0 0.00026 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EME87708.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME87708.1 - 0.0088 15.7 0.0 0.054 13.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME87708.1 - 0.011 15.8 0.0 0.097 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EME87708.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EME87708.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EME87708.1 - 0.019 14.4 0.1 0.045 13.1 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EME87708.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME87708.1 - 0.04 13.8 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 EME87708.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase RuvB_N PF05496.7 EME87708.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EME87708.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EME87709.1 - 2.6e-33 115.7 0.0 3.2e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EME87709.1 - 0.096 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) A_deamin PF02137.13 EME87711.1 - 1.4e-56 192.2 0.0 2.1e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain PHD PF00628.24 EME87712.1 - 4.7e-09 35.8 7.9 8.3e-09 35.0 5.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EME87712.1 - 0.012 15.8 0.1 0.033 14.4 0.0 1.8 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding AICARFT_IMPCHas PF01808.13 EME87712.1 - 0.16 11.0 0.1 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme zf-RING-like PF08746.6 EME87712.1 - 0.17 11.8 2.9 0.32 11.0 2.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.1 EME87712.1 - 0.21 11.7 0.5 0.53 10.4 0.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Fumarate_red_D PF02313.12 EME87713.1 - 0.071 13.0 1.3 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit D IncA PF04156.9 EME87714.1 - 0.13 11.8 2.3 0.14 11.7 1.6 1.1 1 0 0 1 1 1 0 IncA protein DUF755 PF05501.6 EME87714.1 - 9.9 6.2 12.5 14 5.7 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AA_permease_2 PF13520.1 EME87717.1 - 5.2e-51 173.5 50.7 6.6e-51 173.1 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EME87717.1 - 5.6e-24 84.3 42.1 7.8e-24 83.8 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease MIP-T3 PF10243.4 EME87719.1 - 7.2e-05 21.4 40.0 9.1e-05 21.1 27.7 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF350 PF03994.9 EME87719.1 - 1.8 8.3 9.3 3.9 7.2 6.4 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF350) LMBR1 PF04791.11 EME87719.1 - 3.1 6.2 3.9 4.4 5.7 2.7 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein MAP7 PF05672.6 EME87719.1 - 4.8 6.5 69.6 8 5.8 48.3 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family SAPS PF04499.10 EME87719.1 - 5.3 5.5 11.0 7.7 5.0 7.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1772 PF08592.6 EME87720.1 - 3.3e-22 78.7 3.0 4.6e-22 78.2 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF202 PF02656.10 EME87721.1 - 7.6e-26 90.1 2.2 7.6e-26 90.1 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2975 PF11188.3 EME87721.1 - 0.037 13.7 1.5 0.056 13.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) VMA21 PF09446.5 EME87721.1 - 0.06 13.2 2.1 0.089 12.7 1.2 1.4 1 1 0 1 1 1 0 VMA21-like domain E1-E2_ATPase PF00122.15 EME87721.1 - 0.096 11.7 2.4 0.13 11.2 1.6 1.3 1 1 0 1 1 1 0 E1-E2 ATPase Maf1 PF09174.5 EME87724.1 - 4.9e-53 179.6 0.0 7.1e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator SPT2 PF08243.6 EME87724.1 - 0.87 9.9 10.6 0.4 11.0 4.8 2.1 2 0 0 2 2 2 0 SPT2 chromatin protein Clat_adaptor_s PF01217.15 EME87725.1 - 1.8e-47 160.6 1.0 2.2e-47 160.3 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.16 EME87726.1 - 9.6e-10 37.7 0.0 1.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Urb2 PF10441.4 EME87728.1 - 1.2e-30 106.8 0.3 3.4e-30 105.3 0.2 1.7 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.7 EME87729.1 - 8.9e-28 96.0 0.0 1e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) RRM_1 PF00076.17 EME87730.1 - 6.1e-38 128.2 0.9 3.5e-21 74.5 0.2 2.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME87730.1 - 5.2e-30 103.2 0.4 1.7e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME87730.1 - 1.2e-18 66.6 0.0 3.4e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME87730.1 - 2.5e-05 23.9 0.2 0.013 15.2 0.1 2.2 2 0 0 2 2 2 2 Limkain b1 SPT16 PF08644.6 EME87730.1 - 0.037 13.8 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) TRAUB PF08164.7 EME87730.1 - 0.15 12.2 2.5 0.87 9.7 0.4 2.7 1 1 3 4 4 4 0 Apoptosis-antagonizing transcription factor, C-terminal TRAP_beta PF05753.9 EME87730.1 - 0.15 11.1 0.0 2.5 7.2 0.0 2.0 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) TPR_11 PF13414.1 EME87731.1 - 2.3e-25 88.0 8.6 4.4e-11 42.2 0.3 4.6 3 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EME87731.1 - 3.9e-22 76.8 3.9 4.6e-08 32.3 0.0 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME87731.1 - 1.8e-20 71.1 7.4 3.2e-06 26.6 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EME87731.1 - 1.4e-15 57.4 11.2 1e-06 29.2 0.1 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EME87731.1 - 9.1e-15 53.8 8.9 5e-05 23.5 0.4 5.7 4 2 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME87731.1 - 9.3e-14 50.4 1.7 0.023 14.8 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EME87731.1 - 2e-13 49.0 1.7 0.011 15.3 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EME87731.1 - 8.1e-13 48.5 6.6 0.00046 20.4 0.0 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME87731.1 - 2e-11 43.6 5.5 2.7e-06 27.1 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME87731.1 - 9e-10 37.6 5.8 0.023 14.4 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EME87731.1 - 8.4e-07 29.0 0.5 0.00032 20.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EME87731.1 - 1.7e-06 27.8 4.5 0.0034 17.2 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME87731.1 - 4.2e-06 26.8 7.1 3.2 8.4 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EME87731.1 - 1.2e-05 25.2 11.2 0.019 15.0 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EME87731.1 - 0.0019 17.2 5.3 0.22 10.5 0.6 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EME87731.1 - 0.0062 16.3 0.0 2.9 7.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EME87731.1 - 0.0093 15.8 0.2 4.1 7.3 0.1 4.0 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain NatB_MDM20 PF09797.4 EME87731.1 - 0.048 12.3 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_10 PF13374.1 EME87731.1 - 0.085 12.8 3.5 16 5.5 0.7 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CRISPR_Cse2 PF09485.5 EME87731.1 - 0.38 10.7 4.9 0.43 10.6 0.4 2.9 3 1 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF484 PF04340.7 EME87731.1 - 0.73 9.2 5.6 2.1 7.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF484 BTAD PF03704.12 EME87731.1 - 0.9 9.8 11.7 0.2 11.9 0.2 3.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain F-box-like_2 PF13013.1 EME87732.1 - 0.13 11.9 1.2 0.75 9.5 0.8 2.0 1 1 0 1 1 1 0 F-box-like domain NUT_N PF12881.2 EME87732.1 - 0.91 8.5 8.2 1.1 8.3 5.7 1.1 1 0 0 1 1 1 0 NUT protein N terminus RNA_pol_A_bac PF01000.21 EME87733.1 - 2.8e-27 95.0 0.0 5.2e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EME87733.1 - 1.3e-14 53.0 0.0 1.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SNF5 PF04855.7 EME87735.1 - 5.7e-70 235.5 0.0 8e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EME87735.1 - 9.6e-06 24.8 2.3 2.1e-05 23.7 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger GST_N_3 PF13417.1 EME87739.1 - 1.1e-15 57.5 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME87739.1 - 1.3e-12 47.5 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EME87739.1 - 2e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain APS_kinase PF01583.15 EME87740.1 - 7.5e-72 240.1 0.0 9.1e-72 239.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EME87740.1 - 2.6e-06 27.3 0.0 4.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME87740.1 - 6.9e-06 26.8 0.0 1.2e-05 26.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME87740.1 - 0.00014 21.1 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EME87740.1 - 0.00038 20.7 0.1 0.00038 20.7 0.1 1.9 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EME87740.1 - 0.0038 16.7 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME87740.1 - 0.014 15.7 0.2 0.02 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME87740.1 - 0.023 15.0 0.0 0.036 14.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EME87740.1 - 0.03 14.3 0.2 0.074 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.13 EME87740.1 - 0.062 12.3 0.0 0.11 11.6 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.7 EME87740.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.12 EME87740.1 - 0.09 12.1 0.2 4.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Thymidylate kinase PI-PLC-X PF00388.14 EME87741.1 - 3.7e-58 195.0 0.0 5.2e-58 194.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EME87741.1 - 1.1e-35 122.1 0.0 1.9e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EME87741.1 - 0.015 15.0 0.0 0.053 13.3 0.0 1.9 2 0 0 2 2 2 0 C2 domain DUF1556 PF07590.6 EME87743.1 - 0.0053 16.9 0.2 0.0077 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1556) F-box-like PF12937.2 EME87744.1 - 0.022 14.4 0.1 0.15 11.7 0.0 2.6 1 1 1 2 2 2 0 F-box-like UPF1_Zn_bind PF09416.5 EME87745.1 - 9.8e-72 239.5 2.4 1e-71 239.4 0.3 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EME87745.1 - 9.2e-60 201.4 0.0 1.7e-59 200.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME87745.1 - 5e-57 193.2 1.1 7.5e-57 192.6 0.8 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME87745.1 - 1.2e-13 50.5 0.1 4.1e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EME87745.1 - 5.6e-13 48.9 0.8 2.8e-11 43.3 0.5 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EME87745.1 - 9.5e-08 32.0 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EME87745.1 - 3.9e-06 26.5 0.7 0.078 12.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EME87745.1 - 0.00022 20.3 0.3 0.0056 15.7 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EME87745.1 - 0.00038 20.1 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EME87745.1 - 0.0016 17.4 0.1 0.43 9.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Ribosomal_S13_N PF08069.7 EME87745.1 - 0.0038 17.0 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain DEAD PF00270.24 EME87745.1 - 0.013 15.0 0.2 0.029 13.8 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EME87745.1 - 0.014 14.7 0.0 0.22 10.7 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EME87745.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 EME87745.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SRP54 PF00448.17 EME87745.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EME87745.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EME87745.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EME87745.1 - 0.17 11.0 0.0 0.43 9.6 0.0 1.6 2 0 0 2 2 2 0 KaiC Brix PF04427.13 EME87746.1 - 1.7e-48 164.8 0.2 2.2e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain HLH PF00010.21 EME87747.1 - 1.2e-06 28.0 0.1 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF690 PF05108.8 EME87747.1 - 0.02 13.3 0.2 0.028 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF690) DUF725 PF05267.7 EME87748.1 - 0.059 13.2 0.5 0.068 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF725) ABC_membrane_2 PF06472.10 EME87750.1 - 9.7e-108 359.5 1.7 9.7e-108 359.5 1.2 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EME87750.1 - 2.7e-17 63.3 0.0 1.1e-16 61.3 0.0 2.1 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EME87750.1 - 0.0001 22.4 0.0 0.00036 20.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME87750.1 - 0.0063 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EME87750.1 - 0.0078 16.5 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME87750.1 - 0.017 15.0 0.6 0.062 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 EME87750.1 - 0.03 13.5 0.1 0.079 12.1 0.1 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EME87750.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 EME87750.1 - 0.066 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RuvB_N PF05496.7 EME87750.1 - 0.069 12.1 0.1 0.49 9.3 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EME87750.1 - 0.13 11.7 0.1 0.79 9.0 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain Mg_chelatase PF01078.16 EME87750.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytochrom_C_asm PF01578.15 EME87751.1 - 0.045 13.2 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C assembly protein LtrA PF06772.6 EME87753.1 - 1.2e-12 47.3 30.5 1.5e-10 40.5 17.1 3.1 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF1461 PF07314.6 EME87753.1 - 0.048 13.4 6.7 0.052 13.2 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) IMS PF00817.15 EME87756.1 - 8.4e-37 126.2 0.0 1.8e-36 125.1 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EME87756.1 - 4.1e-07 29.9 0.1 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EME87756.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif HHH_8 PF14716.1 EME87756.1 - 0.15 12.2 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Pyrophosphatase PF00719.14 EME87757.1 - 0.031 13.7 3.9 0.49 9.8 0.1 2.7 1 1 1 2 2 2 0 Inorganic pyrophosphatase Reo_sigmaC PF04582.7 EME87757.1 - 0.45 9.6 9.3 0.081 12.0 1.0 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ACR_tran PF00873.14 EME87757.1 - 4.1 4.6 8.1 11 3.3 5.3 1.6 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family DUF745 PF05335.8 EME87757.1 - 5.9 6.3 14.9 0.06 12.8 3.3 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF745) IncA PF04156.9 EME87757.1 - 6.5 6.2 36.0 0.24 10.9 8.5 3.7 1 1 1 3 3 3 0 IncA protein adh_short_C2 PF13561.1 EME87759.1 - 9.4e-28 97.5 0.1 1.2e-27 97.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME87759.1 - 6.7e-23 81.4 0.0 1.2e-22 80.5 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME87759.1 - 5.1e-07 29.5 0.0 7.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME87759.1 - 2.7e-06 27.0 0.0 3.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EME87759.1 - 0.0007 18.5 0.0 0.00095 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RFC1 PF08519.7 EME87760.1 - 2.5e-58 196.2 0.1 6.7e-58 194.8 0.1 1.8 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EME87760.1 - 1.3e-11 44.4 0.0 5.4e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EME87760.1 - 2.4e-09 37.4 0.0 5.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME87760.1 - 3.1e-05 24.1 0.0 8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME87760.1 - 3.9e-05 24.4 0.0 0.00021 22.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EME87760.1 - 0.00041 19.1 0.0 0.00087 18.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EME87760.1 - 0.0013 18.4 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EME87760.1 - 0.0017 18.3 0.0 0.023 14.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EME87760.1 - 0.0021 17.9 0.1 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME87760.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EME87760.1 - 0.012 15.5 0.0 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EME87760.1 - 0.015 15.6 0.1 0.015 15.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EME87760.1 - 0.026 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EME87760.1 - 0.16 11.6 0.0 0.77 9.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Transposase_20 PF02371.11 EME87760.1 - 0.3 11.2 4.1 12 6.0 0.0 3.4 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family Ribosomal_L16 PF00252.13 EME87762.1 - 6.2e-27 93.9 0.0 9.7e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Lipase_GDSL_2 PF13472.1 EME87763.1 - 4.1e-17 62.8 0.2 5e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME87763.1 - 1.7e-08 34.6 0.4 2.3e-08 34.1 0.3 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2183 PF09949.4 EME87764.1 - 6.7e-34 115.8 0.0 1.6e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EME87764.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) CarboxypepD_reg PF13620.1 EME87764.1 - 0.054 13.5 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Methyltransf_23 PF13489.1 EME87766.1 - 9.3e-12 44.9 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME87766.1 - 2.4e-11 43.9 0.0 1.6e-10 41.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME87766.1 - 1.4e-10 41.4 0.0 2.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME87766.1 - 4.2e-10 39.9 0.0 1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87766.1 - 4.8e-09 35.9 0.0 7.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87766.1 - 9.1e-08 32.6 0.0 1.5e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME87766.1 - 0.0012 18.8 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME87766.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EME87766.1 - 0.018 14.6 0.0 3.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EME87766.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 EME87766.1 - 0.056 12.7 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TehB PF03848.9 EME87766.1 - 0.14 11.2 0.0 0.98 8.5 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TehB GST_C_3 PF14497.1 EME87767.1 - 4.1e-05 23.9 0.0 6.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 EME87767.1 - 0.00078 19.6 0.1 0.0028 17.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 EME87767.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EME87767.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein EBP PF05241.7 EME87768.1 - 0.00037 19.5 5.5 0.0011 18.0 3.8 1.7 1 1 0 1 1 1 1 Emopamil binding protein NUP PF06516.6 EME87769.1 - 1.7e-117 391.7 0.1 1.9e-117 391.6 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) DUF3176 PF11374.3 EME87770.1 - 4.8e-28 97.2 0.1 8.3e-28 96.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) TLV_coat PF00429.14 EME87771.1 - 0.056 11.8 5.7 0.064 11.6 4.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Clat_adaptor_s PF01217.15 EME87772.1 - 2.8e-45 153.5 0.0 3.6e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HbrB PF08539.6 EME87774.1 - 6.1e-51 172.3 0.0 8.8e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 HbrB-like YbaJ PF10757.4 EME87776.1 - 0.042 13.9 0.3 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ DUF1183 PF06682.7 EME87777.1 - 6.8 6.1 6.2 9.7 5.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Toxin_3 PF00537.13 EME87778.1 - 0.13 12.1 3.0 0.38 10.6 2.1 1.8 1 0 0 1 1 1 0 Scorpion toxin-like domain tRNA-synt_1 PF00133.17 EME87780.1 - 1.3e-41 142.2 0.0 5.6e-29 100.6 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EME87780.1 - 2.6e-19 69.1 0.1 7.8e-11 41.2 0.0 3.2 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EME87780.1 - 2.3e-10 40.4 0.0 5.3e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EME87780.1 - 7.9e-07 28.4 0.0 2.8e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 EME87780.1 - 0.011 14.9 0.0 4.5 6.2 0.0 2.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DUF3813 PF12758.2 EME87780.1 - 0.013 15.6 0.3 0.039 14.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Fungal_trans_2 PF11951.3 EME87781.1 - 5.1e-14 51.6 0.1 7.1e-14 51.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2277 PF10041.4 EME87781.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) GFO_IDH_MocA PF01408.17 EME87782.1 - 1.5e-22 80.3 0.0 2.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME87782.1 - 3.2e-07 30.1 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Isochorismatase PF00857.15 EME87782.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family TruB_C PF09142.6 EME87782.1 - 0.0087 15.6 0.1 0.91 9.2 0.0 2.6 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal Methyltransf_5 PF01795.14 EME87782.1 - 0.041 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family NAD_binding_2 PF03446.10 EME87782.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EME87782.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_26 PF13659.1 EME87782.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EME87782.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.16 EME87783.1 - 3.2e-51 173.8 0.0 4e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4483 PF14825.1 EME87783.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) CENP-S PF15630.1 EME87784.1 - 1.2e-27 95.8 0.1 1.5e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EME87784.1 - 0.00024 20.7 0.0 0.00039 20.0 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EME87784.1 - 0.00025 20.4 0.2 0.00035 19.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Laminin_I PF06008.9 EME87784.1 - 0.013 14.7 0.3 0.016 14.5 0.2 1.1 1 0 0 1 1 1 0 Laminin Domain I CBFD_NFYB_HMF PF00808.18 EME87784.1 - 0.2 11.7 3.4 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Chitin_bind_3 PF03067.10 EME87785.1 - 0.038 14.2 0.1 0.18 12.0 0.1 1.9 1 1 0 1 1 1 0 Chitin binding domain ADH_N PF08240.7 EME87786.1 - 2.2e-29 101.4 0.0 4.3e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME87786.1 - 2.2e-19 69.2 0.6 4.2e-19 68.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EME87786.1 - 0.023 14.0 2.6 0.055 12.8 1.7 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Hydantoinase_A PF01968.13 EME87786.1 - 0.034 13.2 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase AlaDh_PNT_C PF01262.16 EME87786.1 - 0.044 13.3 0.4 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EME87786.1 - 0.056 13.5 2.5 0.99 9.4 1.3 2.7 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EME87786.1 - 0.06 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain LsmAD PF06741.8 EME87786.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 LsmAD domain AdoHcyase_NAD PF00670.16 EME87786.1 - 0.073 12.9 0.4 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 EME87786.1 - 0.086 11.2 2.4 0.12 10.7 1.7 1.1 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 EME87786.1 - 0.087 12.6 1.9 0.25 11.1 1.3 1.8 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.19 EME87786.1 - 0.088 11.6 1.6 0.12 11.1 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EME87786.1 - 0.17 11.9 0.3 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EME87787.1 - 1.7e-32 112.6 0.8 2.4e-32 112.1 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME87787.1 - 7.6e-23 81.5 0.0 9.3e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME87787.1 - 1.5e-13 50.8 0.4 2.3e-13 50.2 0.3 1.5 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EME87787.1 - 1.8e-05 24.4 0.3 3.2e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EME87787.1 - 6.2e-05 22.5 0.1 8.1e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CW_binding_2 PF04122.7 EME87787.1 - 0.0089 16.2 0.1 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative cell wall binding repeat 2 NmrA PF05368.8 EME87787.1 - 0.016 14.4 0.2 0.026 13.7 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_5 PF08323.6 EME87787.1 - 0.045 13.2 0.0 0.27 10.6 0.0 2.1 2 1 1 3 3 3 0 Starch synthase catalytic domain ApbA PF02558.11 EME87787.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Oxidored_nitro PF00148.14 EME87787.1 - 0.051 12.1 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_10 PF13460.1 EME87787.1 - 0.054 13.4 0.5 0.11 12.4 0.4 1.5 1 1 0 1 1 1 0 NADH(P)-binding ETF PF01012.16 EME87787.1 - 0.081 12.6 0.3 0.42 10.2 0.0 2.1 2 1 0 2 2 2 0 Electron transfer flavoprotein domain THF_DHG_CYH_C PF02882.14 EME87787.1 - 0.086 11.9 0.1 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EME87787.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EME87787.1 - 0.19 10.6 0.8 0.26 10.1 0.2 1.6 2 1 0 2 2 2 0 RmlD substrate binding domain DUF706 PF05153.10 EME87788.1 - 1.1e-126 421.3 1.0 1.6e-126 420.7 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) Bromodomain PF00439.20 EME87789.1 - 1.1e-41 140.6 2.8 5.4e-20 71.0 0.3 3.3 3 0 0 3 3 3 2 Bromodomain Utp12 PF04003.7 EME87790.1 - 4e-19 68.5 0.6 7.1e-19 67.7 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.5 EME87790.1 - 0.69 8.9 43.8 0.31 10.0 14.1 2.2 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.7 EME87790.1 - 3.9 6.6 49.7 1.5 8.0 18.2 2.3 2 0 0 2 2 2 0 SDA1 FAM60A PF15396.1 EME87790.1 - 7.4 6.2 10.9 2.7 7.6 1.3 2.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF4050 PF13259.1 EME87791.1 - 7.5e-32 109.8 0.2 1.4e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Nop25 PF09805.4 EME87791.1 - 1.3 9.1 6.7 0.4 10.7 1.8 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Pyr_redox_3 PF13738.1 EME87794.1 - 1.7e-25 90.3 0.0 1.2e-24 87.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME87794.1 - 7.4e-13 47.5 0.0 6.7e-11 41.0 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME87794.1 - 3.3e-10 39.4 0.1 1.8e-08 33.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME87794.1 - 1.8e-08 34.2 0.0 6.2e-08 32.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME87794.1 - 2.6e-06 27.2 0.3 0.0049 16.6 0.0 3.3 2 2 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EME87794.1 - 7.1e-05 21.8 0.0 0.099 11.5 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME87794.1 - 0.00086 19.2 0.0 0.12 12.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME87794.1 - 0.0076 15.3 0.0 0.033 13.2 0.0 2.0 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EME87794.1 - 0.027 13.3 0.1 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EME87794.1 - 0.039 12.4 0.1 0.065 11.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF1751 PF08551.5 EME87795.1 - 1e-25 89.9 0.7 2.1e-25 88.8 0.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EME87795.1 - 9.5e-05 22.4 8.1 0.00015 21.7 5.6 1.3 1 0 0 1 1 1 1 Rhomboid family Polysacc_synt_C PF14667.1 EME87795.1 - 8.2 6.2 10.0 3.6 7.3 2.7 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.27 EME87796.1 - 2.7e-07 30.2 3.4 0.81 9.6 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat LisH PF08513.6 EME87796.1 - 8.1e-06 25.4 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 LisH PD40 PF07676.7 EME87796.1 - 0.00048 19.7 0.1 1.8 8.3 0.0 3.3 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EME87796.1 - 0.0019 16.1 0.0 0.46 8.2 0.0 2.9 3 1 1 4 4 4 3 IKI3 family DUF1028 PF06267.7 EME87796.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) F-box-like PF12937.2 EME87797.1 - 0.0036 16.9 2.0 0.0082 15.8 0.0 2.3 2 0 0 2 2 2 1 F-box-like PC4 PF02229.11 EME87798.1 - 8.8e-05 21.6 0.0 0.00017 20.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) TPR_MLP1_2 PF07926.7 EME87798.1 - 0.016 14.9 45.7 0.13 12.0 11.0 3.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein YejG PF13989.1 EME87798.1 - 0.027 14.5 0.3 0.12 12.4 0.1 2.2 1 1 0 1 1 1 0 YejG-like protein bZIP_1 PF00170.16 EME87798.1 - 3.7 7.5 23.5 0.79 9.7 3.4 4.1 4 1 0 4 4 4 0 bZIP transcription factor DUF904 PF06005.7 EME87798.1 - 10 6.5 31.6 0.81 10.0 4.9 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF904) Abhydrolase_3 PF07859.8 EME87799.1 - 3.5e-31 108.4 0.0 4.8e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EME87799.1 - 4.1e-20 71.7 0.0 5.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EME87799.1 - 6.2e-10 39.0 0.0 9.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME87799.1 - 0.06 12.5 0.0 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family p450 PF00067.17 EME87800.1 - 9.9e-67 225.4 0.0 1.3e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ctf8 PF09696.5 EME87801.1 - 1.4e-22 79.7 0.0 2.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ctf8 GrpE PF01025.14 EME87802.1 - 3.6e-43 146.9 9.9 5.3e-43 146.4 6.9 1.3 1 1 0 1 1 1 1 GrpE CFIA_Pcf11 PF11526.3 EME87802.1 - 0.041 14.0 0.3 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Cytochrom_B562 PF07361.6 EME87802.1 - 0.07 13.5 4.0 0.058 13.8 1.8 1.6 1 1 0 1 1 1 0 Cytochrome b562 GET2 PF08690.5 EME87802.1 - 0.5 9.5 4.8 0.67 9.1 3.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 HSP70 PF00012.15 EME87802.1 - 1.4 6.7 10.1 1.7 6.4 7.0 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF1664 PF07889.7 EME87802.1 - 2 8.2 4.6 9.7 6.0 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Amidohydro_2 PF04909.9 EME87803.1 - 1.1e-17 64.4 0.0 1.6e-17 63.9 0.0 1.2 1 1 0 1 1 1 1 Amidohydrolase SecY PF00344.15 EME87805.1 - 8.7e-94 314.2 9.6 1.2e-93 313.8 6.7 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EME87805.1 - 2.3e-18 65.4 0.3 6e-18 64.0 0.2 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p BCDHK_Adom3 PF10436.4 EME87807.1 - 3.8e-70 234.6 0.0 5.5e-70 234.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EME87807.1 - 1.6e-17 63.2 0.0 3.7e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EME87807.1 - 0.016 14.8 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRF PF01765.14 EME87807.1 - 0.078 12.4 0.2 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Methyltransf_2 PF00891.13 EME87808.1 - 4.4e-21 75.1 0.2 7.2e-21 74.4 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EME87808.1 - 9e-05 23.0 0.2 0.00026 21.5 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EME87808.1 - 0.0019 17.6 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME87808.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_2d PF01409.15 EME87809.1 - 6.4e-48 163.1 0.4 1.9e-24 86.2 0.0 2.5 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EME87809.1 - 2.8e-26 91.4 0.0 6e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EME87810.1 - 1.4e-59 197.8 1.9 2.4e-20 72.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RL11D PF11088.3 EME87810.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 AAA PF00004.24 EME87811.1 - 5.3e-91 301.7 0.0 3.1e-44 150.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME87811.1 - 1e-12 47.6 0.0 4e-06 26.0 0.0 3.2 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EME87811.1 - 1.4e-11 44.2 0.7 1.1e-05 25.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME87811.1 - 1.7e-11 44.4 0.4 0.0009 19.2 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EME87811.1 - 1.1e-10 41.7 0.2 0.018 15.1 0.0 5.0 3 2 0 3 3 3 2 AAA domain AAA_2 PF07724.9 EME87811.1 - 1.8e-10 40.9 0.0 0.0014 18.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EME87811.1 - 2.1e-09 36.8 4.9 0.00078 18.5 0.0 4.4 4 1 1 5 5 4 2 Zeta toxin AAA_33 PF13671.1 EME87811.1 - 2.2e-09 37.3 0.3 0.00021 21.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EME87811.1 - 8.5e-09 35.0 8.1 0.17 11.2 0.0 5.4 4 2 2 6 6 6 3 AAA domain AAA_14 PF13173.1 EME87811.1 - 9.4e-09 35.2 0.0 0.0057 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME87811.1 - 1.8e-08 35.2 0.0 0.00097 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EME87811.1 - 1.4e-07 31.1 0.1 0.016 14.9 0.0 3.4 3 0 0 3 3 2 2 Part of AAA domain NACHT PF05729.7 EME87811.1 - 5.7e-07 29.3 0.7 0.022 14.4 0.0 4.1 3 1 1 4 4 4 1 NACHT domain AAA_28 PF13521.1 EME87811.1 - 1e-06 28.7 0.0 0.0024 17.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EME87811.1 - 1.1e-06 28.2 0.0 0.0011 18.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EME87811.1 - 1.4e-06 28.4 0.0 0.032 14.3 0.0 2.9 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EME87811.1 - 1.5e-06 27.5 0.7 0.032 13.3 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EME87811.1 - 1.9e-06 26.8 0.1 0.015 14.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 EME87811.1 - 2.4e-06 27.8 0.0 0.024 14.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EME87811.1 - 6.6e-06 25.6 0.0 0.072 12.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EME87811.1 - 2.3e-05 24.2 0.0 0.14 11.8 0.0 3.4 2 2 1 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 EME87811.1 - 2.3e-05 24.6 0.0 0.42 10.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.13 EME87811.1 - 0.00017 21.2 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EME87811.1 - 0.00023 20.1 0.0 0.5 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) UPF0079 PF02367.12 EME87811.1 - 0.00026 20.5 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EME87811.1 - 0.00035 19.8 0.1 0.41 9.8 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.13 EME87811.1 - 0.00049 19.8 0.0 1.8 8.1 0.0 3.7 2 2 1 3 3 3 1 Bacterial dnaA protein Rad17 PF03215.10 EME87811.1 - 0.0005 18.8 0.0 0.13 10.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EME87811.1 - 0.0006 19.4 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AFG1_ATPase PF03969.11 EME87811.1 - 0.00064 18.6 0.3 2.9 6.5 0.0 3.3 3 0 0 3 3 3 1 AFG1-like ATPase SKI PF01202.17 EME87811.1 - 0.0011 18.8 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Sigma54_activat PF00158.21 EME87811.1 - 0.0012 18.4 0.0 1.3 8.4 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EME87811.1 - 0.0021 17.6 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EME87811.1 - 0.0035 16.2 0.1 2.8 6.7 0.0 2.8 3 0 0 3 3 2 1 NB-ARC domain NTPase_1 PF03266.10 EME87811.1 - 0.0061 16.2 0.1 7.8 6.1 0.0 3.2 2 1 0 3 3 3 0 NTPase Sigma54_activ_2 PF14532.1 EME87811.1 - 0.0067 16.4 0.1 2.8 7.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EME87811.1 - 0.0069 15.9 0.3 0.88 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EME87811.1 - 0.0074 15.4 0.1 4 6.4 0.0 3.1 3 0 0 3 3 3 0 KaiC ResIII PF04851.10 EME87811.1 - 0.023 14.5 0.0 3.5 7.3 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 EME87811.1 - 0.042 13.3 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EME87811.1 - 0.05 14.1 0.0 3.2 8.2 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EME87811.1 - 0.055 12.9 1.1 15 4.8 0.0 3.7 4 0 0 4 4 4 0 AAA-like domain cobW PF02492.14 EME87811.1 - 0.073 12.5 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EME87811.1 - 0.077 11.9 0.0 8 5.3 0.0 2.8 2 1 0 3 3 3 0 KAP family P-loop domain Parvo_NS1 PF01057.12 EME87811.1 - 0.1 11.4 0.1 8.6 5.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.18 EME87811.1 - 0.12 12.3 0.0 14 5.6 0.0 3.4 2 2 0 2 2 2 0 50S ribosome-binding GTPase DAP3 PF10236.4 EME87811.1 - 0.14 11.0 0.0 6.1 5.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Snf7 PF03357.16 EME87812.1 - 5.2e-36 123.6 13.1 6.1e-36 123.3 9.1 1.1 1 0 0 1 1 1 1 Snf7 DUF1938 PF09153.5 EME87812.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) DUF2203 PF09969.4 EME87812.1 - 0.54 10.4 6.0 0.92 9.7 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Bcr-Abl_Oligo PF09036.5 EME87812.1 - 2 8.4 4.4 0.64 10.0 0.6 1.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain PITH PF06201.8 EME87813.1 - 2.5e-47 160.4 0.0 3e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain PhoD PF09423.5 EME87814.1 - 1.5e-10 40.2 0.1 3.3e-09 35.8 0.1 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase Gly-zipper_OmpA PF13436.1 EME87814.1 - 2.2 7.9 11.7 1.1 8.9 4.7 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain FCH PF00611.18 EME87816.1 - 1.6e-23 82.7 1.2 1.5e-22 79.5 0.0 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EME87816.1 - 8.2e-20 69.9 0.0 7e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EME87816.1 - 6.5e-18 64.0 0.2 1.2e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EME87816.1 - 1.2e-12 47.3 5.0 2e-12 46.6 3.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 EME87816.1 - 6.2e-09 35.2 0.0 0.0028 17.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EME87816.1 - 0.002 18.2 0.2 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain PHD PF00628.24 EME87816.1 - 1.4 8.6 6.1 2.9 7.6 4.3 1.5 1 0 0 1 1 1 0 PHD-finger Prominin PF05478.6 EME87816.1 - 4.6 4.6 6.0 0.87 7.0 1.7 1.5 2 0 0 2 2 2 0 Prominin DEAD PF00270.24 EME87817.1 - 7e-31 106.9 0.1 6.1e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME87817.1 - 4e-23 81.0 0.1 9e-23 79.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EME87817.1 - 0.0045 16.6 0.1 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.20 EME87817.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) MinC_C PF03775.11 EME87818.1 - 0.09 12.4 0.1 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain NMDAR2_C PF10565.4 EME87818.1 - 4.9 5.7 6.5 6.6 5.2 4.5 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Glyco_hydro_72 PF03198.9 EME87820.1 - 1e-130 435.3 2.5 1.2e-130 435.0 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EME87820.1 - 1.7e-05 24.1 0.1 0.00016 20.9 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EME87820.1 - 0.00032 19.7 0.0 0.00059 18.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 EME87821.1 - 6.5e-85 285.3 11.3 8.5e-85 284.9 7.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87821.1 - 9e-33 113.4 53.4 1.1e-28 100.0 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME87821.1 - 6.2e-06 24.8 20.0 0.0057 15.1 0.6 3.8 1 1 2 3 3 3 3 MFS/sugar transport protein Sec62 PF03839.11 EME87821.1 - 0.25 10.7 8.2 0.2 11.0 1.2 2.3 2 0 0 2 2 2 0 Translocation protein Sec62 Oxidored_FMN PF00724.15 EME87822.1 - 1.1e-92 310.7 0.0 1.3e-92 310.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SH3_9 PF14604.1 EME87824.1 - 2.8e-31 106.8 6.5 1.7e-15 56.2 0.1 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 EME87824.1 - 3.6e-30 103.1 5.3 3.8e-15 54.9 0.5 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EME87824.1 - 1.9e-18 65.6 0.0 3.7e-08 32.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EME87824.1 - 1.4e-11 44.3 0.0 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box PF00646.28 EME87825.1 - 5.6e-05 22.6 0.1 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EME87826.1 - 1.4e-33 116.0 26.3 1.4e-33 116.0 18.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EME87826.1 - 0.0028 16.2 11.7 0.0066 15.0 2.1 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter DUF1989 PF09347.5 EME87828.1 - 6.8e-10 38.6 0.0 3.2e-09 36.4 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1989) OKR_DC_1 PF01276.15 EME87828.1 - 0.07 11.6 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Asp PF00026.18 EME87831.1 - 1.6e-07 30.8 0.4 9.8e-07 28.3 0.3 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EME87831.1 - 7.7e-05 21.9 1.0 0.00015 21.0 0.1 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EME87831.1 - 0.0079 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain PTPA PF03095.10 EME87832.1 - 8.3e-107 356.7 0.0 1e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SKG6 PF08693.5 EME87833.1 - 0.001 18.2 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EME87833.1 - 0.0036 16.7 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kdo PF06293.9 EME87834.1 - 4.2e-14 52.0 0.0 5.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EME87834.1 - 1e-09 37.9 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EME87834.1 - 1.6e-09 37.8 1.5 0.00027 20.7 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EME87834.1 - 1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EME87834.1 - 6.7e-05 22.0 0.0 8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 EME87834.1 - 0.00015 20.9 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EME87834.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tantalus PF15386.1 EME87835.1 - 0.039 13.7 0.1 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Drosophila Tantalus-like Herpes_capsid PF06112.6 EME87835.1 - 7.6 6.5 10.0 4.1 7.4 5.7 1.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RNase_T PF00929.19 EME87836.1 - 2.1e-08 34.6 0.0 3e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 Exonuclease DUF676 PF05057.9 EME87837.1 - 7.1e-49 166.0 0.0 1e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EME87837.1 - 9.1e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME87837.1 - 0.00037 20.2 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EME87837.1 - 0.00059 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EME87837.1 - 0.04 13.0 0.1 0.12 11.4 0.1 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 EME87837.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EME87837.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family ATP-synt_ab PF00006.20 EME87838.1 - 3.1e-69 232.7 0.0 4.5e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME87838.1 - 2.7e-26 92.2 0.3 9e-26 90.5 0.2 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EME87838.1 - 3e-16 59.3 3.6 8.4e-16 57.9 2.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EME87838.1 - 0.022 14.6 1.1 0.022 14.6 0.7 1.9 2 0 0 2 2 2 0 HAS barrel domain DUF962 PF06127.6 EME87839.1 - 2e-22 78.8 2.0 2.9e-22 78.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) CorA PF01544.13 EME87839.1 - 0.26 10.2 3.9 0.39 9.6 2.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Nop16 PF09420.5 EME87840.1 - 1.7e-47 161.5 11.1 2.1e-47 161.2 7.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Not3 PF04065.10 EME87840.1 - 0.026 13.8 1.4 0.026 13.8 0.9 2.8 1 1 2 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Myb_DNA-bind_6 PF13921.1 EME87840.1 - 0.061 13.4 1.7 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain HpaB PF03241.8 EME87840.1 - 0.091 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Mis14 PF08641.7 EME87840.1 - 0.11 12.5 2.4 0.17 11.9 1.3 1.6 1 1 0 1 1 1 0 Kinetochore protein Mis14 like GRA6 PF05084.8 EME87840.1 - 0.66 9.4 3.6 0.26 10.7 0.2 1.8 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Zip PF02535.17 EME87841.1 - 1.3e-54 185.3 8.7 1.1e-53 182.3 6.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter GTP_cyclohydro2 PF00925.15 EME87844.1 - 1.2e-55 187.3 0.0 6.4e-51 171.9 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II IU_nuc_hydro PF01156.14 EME87845.1 - 4e-54 183.9 0.0 1.6e-41 142.5 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase BH3 PF15285.1 EME87845.1 - 0.0033 16.8 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting Transketolase_C PF02780.15 EME87845.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain IpgD PF05925.7 EME87845.1 - 0.19 9.9 0.0 0.26 9.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD DUF1903 PF08991.5 EME87846.1 - 9.7e-24 83.3 10.3 1.1e-23 83.1 7.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EME87846.1 - 0.0076 16.1 9.5 0.013 15.3 6.6 1.4 1 0 0 1 1 1 1 CHCH domain EGF_MSP1_1 PF12946.2 EME87846.1 - 0.036 13.8 5.9 0.084 12.6 4.1 1.8 1 1 0 1 1 1 0 MSP1 EGF domain 1 Cmc1 PF08583.5 EME87846.1 - 0.72 9.6 8.0 0.28 10.9 2.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Brr6_like_C_C PF10104.4 EME87846.1 - 1.1 8.8 4.5 1.1 8.7 3.1 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Rad60-SLD PF11976.3 EME87848.1 - 2.1e-20 72.1 0.1 2.7e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EME87848.1 - 2.6e-07 29.9 0.4 3.5e-07 29.5 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin family Alpha_GJ PF03229.8 EME87849.1 - 5.3 7.3 7.7 0.66 10.3 2.3 1.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J MatE PF01554.13 EME87850.1 - 2e-58 196.6 17.8 3.3e-33 114.5 2.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EME87850.1 - 2.7e-09 36.9 6.3 2.7e-09 36.9 4.4 3.9 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.16 EME87851.1 - 3.3e-88 295.6 0.0 5.1e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EME87851.1 - 0.075 13.2 0.1 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 UPF0489 domain Ald_Xan_dh_C2 PF02738.13 EME87852.1 - 4.9e-200 665.4 1.0 6.7e-200 665.0 0.7 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EME87852.1 - 1.8e-48 164.1 0.0 3.4e-48 163.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EME87852.1 - 3.7e-33 113.8 0.0 8.6e-33 112.7 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EME87852.1 - 3.7e-32 110.3 0.0 1.1e-31 108.8 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EME87852.1 - 8.6e-29 99.2 0.0 1.8e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EME87852.1 - 4.2e-08 32.8 2.5 4.5e-08 32.7 0.1 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r3 PF04539.11 EME87852.1 - 0.0026 17.6 0.3 0.054 13.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-70 region 3 GCN5L1 PF06320.8 EME87853.1 - 1.4e-11 44.2 4.0 1.7e-11 44.0 2.8 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) RmuC PF02646.11 EME87853.1 - 0.0003 19.7 0.6 0.00033 19.6 0.4 1.2 1 0 0 1 1 1 1 RmuC family TMP_2 PF06791.8 EME87853.1 - 0.033 13.7 7.6 0.045 13.3 5.3 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4337 PF14235.1 EME87853.1 - 0.072 12.9 5.2 0.099 12.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ABC_tran_2 PF12848.2 EME87853.1 - 0.08 12.7 3.6 0.13 12.1 2.5 1.4 1 0 0 1 1 1 0 ABC transporter ERp29_N PF07912.8 EME87853.1 - 0.081 12.8 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain Tektin PF03148.9 EME87853.1 - 0.12 10.9 6.2 0.11 11.0 3.7 1.3 1 1 0 1 1 1 0 Tektin family DUF3153 PF11353.3 EME87853.1 - 0.16 11.4 1.5 0.2 11.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) AAA_13 PF13166.1 EME87853.1 - 0.17 10.3 4.5 0.2 10.0 3.1 1.0 1 0 0 1 1 1 0 AAA domain Microtub_assoc PF07989.6 EME87853.1 - 0.2 11.4 3.5 0.25 11.2 1.4 1.8 2 0 0 2 2 2 0 Microtubule associated Rabaptin PF03528.10 EME87853.1 - 0.22 11.4 7.9 2.2 8.2 5.5 2.1 1 1 0 1 1 1 0 Rabaptin HAUS6_N PF14661.1 EME87853.1 - 0.4 9.9 5.4 0.48 9.7 3.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TPR_MLP1_2 PF07926.7 EME87853.1 - 0.55 9.9 9.1 0.78 9.4 6.3 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ZapA PF05164.8 EME87853.1 - 0.65 9.9 5.4 1.6 8.7 3.7 1.7 1 1 0 1 1 1 0 Cell division protein ZapA Syntaxin-6_N PF09177.6 EME87853.1 - 0.74 10.2 3.7 1.1 9.6 0.7 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Syntaxin-6_N PF09177.6 EME87854.1 - 0.037 14.4 0.3 0.25 11.7 0.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.4 EME87854.1 - 0.038 13.8 0.8 5.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XkdW PF09636.5 EME87854.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 XkdW protein FlaC_arch PF05377.6 EME87854.1 - 0.13 12.1 0.2 10 6.1 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Flg_hook PF02120.11 EME87854.1 - 1.2 8.8 5.3 1.1 8.9 0.8 2.8 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK EamA PF00892.15 EME87855.1 - 1.2e-08 35.0 23.7 3.7e-06 27.0 0.6 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EME87855.1 - 0.00084 19.5 5.2 0.00084 19.5 3.6 3.7 2 2 0 3 3 3 1 Multidrug resistance efflux transporter Aldo_ket_red PF00248.16 EME87856.1 - 1.2e-49 168.6 0.0 1.4e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_int_SAM_3 PF14659.1 EME87856.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Fungal_trans PF04082.13 EME87857.1 - 7.6e-17 61.0 0.0 1.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME87857.1 - 1.7e-09 37.4 9.4 2.8e-09 36.7 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin PF02996.12 EME87858.1 - 9.4e-23 80.1 0.1 1.3e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EME87858.1 - 7.8e-05 22.3 1.7 0.019 14.7 0.0 2.1 2 0 0 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 EME87858.1 - 0.0013 18.6 0.9 0.0013 18.6 0.6 1.6 2 0 0 2 2 1 1 Centrosome microtubule-binding domain of Cep57 CENP-Q PF13094.1 EME87858.1 - 0.0095 15.9 2.0 2.8 7.9 0.4 2.1 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 EME87858.1 - 0.013 15.6 1.4 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_3 PF13758.1 EME87858.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.7 EME87858.1 - 0.049 13.4 2.7 1.9 8.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EME87858.1 - 0.051 13.3 1.7 1.2 8.9 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding WXG100 PF06013.7 EME87858.1 - 0.08 12.9 3.4 0.36 10.8 0.4 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG IncA PF04156.9 EME87858.1 - 0.082 12.4 2.5 0.14 11.7 1.5 1.6 1 1 0 1 1 1 0 IncA protein CCDC155 PF14662.1 EME87858.1 - 0.089 12.3 4.3 0.35 10.4 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 CobU PF02283.11 EME87858.1 - 0.091 12.1 0.3 0.55 9.6 0.2 1.9 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Sec20 PF03908.8 EME87858.1 - 0.14 11.8 2.7 0.12 12.0 0.4 2.0 2 1 1 3 3 3 0 Sec20 HSBP1 PF06825.7 EME87858.1 - 0.19 11.3 0.9 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Spc7 PF08317.6 EME87858.1 - 0.21 10.2 6.0 0.11 11.1 1.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.8 EME87858.1 - 0.25 10.7 2.1 4.2 6.7 0.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region Serine_rich PF08824.5 EME87858.1 - 0.26 10.9 1.9 0.31 10.7 0.5 1.6 2 0 0 2 2 2 0 Serine rich protein interaction domain Jnk-SapK_ap_N PF09744.4 EME87858.1 - 0.29 11.1 2.2 4.9 7.1 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.3 EME87858.1 - 3.3 7.5 7.0 12 5.7 0.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APH PF01636.18 EME87859.1 - 7.4e-12 45.5 0.4 2.8e-10 40.3 0.3 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family bZIP_1 PF00170.16 EME87861.1 - 1.6e-08 34.3 0.6 2.3e-08 33.8 0.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME87861.1 - 5.9e-08 32.4 0.5 1e-07 31.6 0.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME87861.1 - 0.05 13.8 0.5 0.083 13.2 0.3 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor EMP24_GP25L PF01105.19 EME87862.1 - 1.4e-47 161.7 0.0 1.7e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Myb_DNA-bind_6 PF13921.1 EME87863.1 - 1.5e-16 60.1 4.8 6.4e-08 32.5 0.0 4.0 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME87863.1 - 1.7e-09 37.5 9.8 0.0015 18.5 0.0 4.4 4 1 0 4 4 4 2 Myb-like DNA-binding domain DUF4292 PF14125.1 EME87863.1 - 0.062 12.7 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4292) HTH_AsnC-type PF13404.1 EME87863.1 - 0.076 12.5 0.0 0.51 9.9 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MADF_DNA_bdg PF10545.4 EME87863.1 - 0.11 12.6 6.9 0.58 10.3 0.1 3.2 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DDE_Tnp_4 PF13359.1 EME87865.1 - 9.2e-14 51.3 0.0 1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EME87865.1 - 0.0028 17.2 0.9 0.0058 16.1 0.7 1.6 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 EME87865.1 - 0.0087 16.2 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 EME87865.1 - 0.051 12.9 1.0 0.12 11.6 0.7 1.7 1 1 0 1 1 1 0 Plant transposon protein Aa_trans PF01490.13 EME87866.1 - 1e-27 96.6 16.5 1.5e-27 96.1 11.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tubulin PF00091.20 EME87869.1 - 2.7e-70 236.5 0.0 5e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EME87869.1 - 1.2e-48 164.2 0.0 2.1e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EME87869.1 - 1.9e-05 24.6 0.0 5.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EME87869.1 - 0.004 16.6 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF818 PF05677.7 EME87870.1 - 0.017 13.8 0.0 0.018 13.7 0.0 1.0 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LRR_8 PF13855.1 EME87871.1 - 3.6e-09 36.2 0.0 0.0021 17.7 0.0 4.3 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EME87871.1 - 3.4e-05 23.3 3.4 0.96 9.1 0.0 4.9 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EME87871.1 - 0.069 13.2 0.5 59 4.2 0.0 4.9 7 0 0 7 7 7 0 Leucine Rich Repeat GATA PF00320.22 EME87871.1 - 0.11 11.9 0.6 0.31 10.4 0.4 1.8 1 0 0 1 1 1 0 GATA zinc finger TFIIF_alpha PF05793.7 EME87871.1 - 0.15 10.4 11.0 0.21 9.9 7.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HSP70 PF00012.15 EME87872.1 - 7.9e-13 47.1 0.0 3.1e-11 41.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Filament PF00038.16 EME87873.1 - 6.4e-05 22.5 6.8 0.00014 21.4 4.7 1.6 1 0 0 1 1 1 1 Intermediate filament protein APG6 PF04111.7 EME87873.1 - 0.064 12.3 11.2 0.12 11.4 7.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4206 PF13901.1 EME87873.1 - 0.08 12.4 0.5 0.18 11.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Vfa1 PF08432.5 EME87873.1 - 0.19 11.7 11.6 0.41 10.6 8.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Erp_C PF06780.6 EME87873.1 - 0.22 11.3 5.4 0.49 10.2 3.7 1.5 1 0 0 1 1 1 0 Erp protein C-terminus DUF342 PF03961.8 EME87873.1 - 0.73 8.1 6.7 1.3 7.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lzipper-MIP1 PF14389.1 EME87873.1 - 1 9.4 12.0 4.3 7.5 7.3 2.7 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Sec2p PF06428.6 EME87873.1 - 1.2 8.9 12.2 6.4 6.6 8.5 2.3 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.1 EME87873.1 - 2.1 7.2 12.6 4.2 6.2 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ACCA PF03255.9 EME87873.1 - 3.4 7.2 8.9 4.4 6.8 0.4 3.0 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pro_CA PF00484.14 EME87875.1 - 4e-26 91.8 0.0 5.9e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase S-methyl_trans PF02574.11 EME87876.1 - 2.2e-77 260.3 0.0 3.7e-77 259.6 0.0 1.4 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Vps26 PF03643.10 EME87877.1 - 7.3e-124 411.9 0.1 8.6e-124 411.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EME87877.1 - 9.4e-05 22.2 0.1 0.0038 17.0 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain 2-oxoacid_dh PF00198.18 EME87878.1 - 9.8e-73 244.2 0.3 1.4e-72 243.6 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EME87878.1 - 6.4e-18 64.1 0.0 1.2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EME87878.1 - 2.5e-13 49.4 0.0 4.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Aldedh PF00171.17 EME87879.1 - 8.5e-100 334.2 0.0 1.1e-99 333.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_33 PF13671.1 EME87880.1 - 9.6e-12 44.9 0.0 1.2e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EME87880.1 - 8e-11 42.0 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EME87880.1 - 7.5e-08 33.2 0.0 9.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EME87880.1 - 1.7e-07 31.6 0.0 2.9e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EME87880.1 - 0.00081 19.5 0.0 0.0013 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EME87880.1 - 0.0038 17.2 0.2 0.014 15.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME87880.1 - 0.0077 16.1 0.0 0.068 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EME87880.1 - 0.0087 15.6 0.0 0.02 14.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EME87880.1 - 0.0097 16.1 0.1 0.017 15.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EME87880.1 - 0.011 15.2 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 EME87880.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 EME87880.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EME87880.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 EME87880.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 EME87880.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EME87880.1 - 0.031 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME87880.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EME87880.1 - 0.037 13.7 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EME87880.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EME87880.1 - 0.051 13.1 0.1 0.13 11.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 EME87880.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.15 EME87880.1 - 0.061 12.9 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 EME87880.1 - 0.076 12.4 0.2 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 EME87880.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EME87880.1 - 0.09 12.4 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 EME87880.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EME87880.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase HAD_2 PF13419.1 EME87881.1 - 1.6e-27 96.8 0.0 2e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME87881.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ras PF00071.17 EME87884.1 - 1.2e-57 193.8 0.0 1.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME87884.1 - 1.1e-19 71.1 0.0 2.1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME87884.1 - 2.7e-14 52.7 0.0 4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME87884.1 - 1.3e-09 37.5 0.0 1.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME87884.1 - 4.1e-08 32.8 0.0 9.1e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EME87884.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EME87884.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Ferric_reduct PF01794.14 EME87885.1 - 6.6e-20 71.4 10.2 1.7e-19 70.1 6.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME87885.1 - 7.6e-18 64.3 0.0 2.1e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EME87885.1 - 1.9e-17 63.6 0.0 1.3e-11 44.6 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain GST_N_3 PF13417.1 EME87886.1 - 1.3e-13 50.9 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EME87886.1 - 1e-10 41.4 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EME87886.1 - 2.1e-10 40.3 0.0 4.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME87886.1 - 3e-10 40.1 0.0 6.9e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME87886.1 - 5e-10 39.2 0.0 9.1e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EME87886.1 - 4.9e-08 33.3 0.1 1e-07 32.3 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sen15 PF09631.5 EME87887.1 - 1.6e-24 86.0 0.0 4.4e-23 81.4 0.0 2.1 1 1 0 1 1 1 1 Sen15 protein Fungal_trans PF04082.13 EME87888.1 - 2.5e-28 98.6 0.0 4.1e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME87888.1 - 1.4e-09 37.6 10.9 2.8e-09 36.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FATC PF02260.15 EME87888.1 - 0.11 11.9 1.0 0.31 10.5 0.1 2.2 2 0 0 2 2 2 0 FATC domain V-SNARE_C PF12352.3 EME87889.1 - 2e-13 50.2 0.5 2e-13 50.2 0.4 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Vps52 PF04129.7 EME87889.1 - 0.014 13.9 1.5 0.021 13.3 1.0 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family Reo_sigmaC PF04582.7 EME87889.1 - 0.71 8.9 5.1 0.43 9.7 1.7 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HrpB7 PF09486.5 EME87889.1 - 1.5 8.6 16.5 0.19 11.6 1.2 3.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) PDDEXK_1 PF12705.2 EME87889.1 - 2.1 7.6 6.8 2.9 7.1 4.5 1.4 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily APG6 PF04111.7 EME87889.1 - 9.8 5.1 15.7 16 4.4 7.1 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Ribosomal_L29 PF00831.18 EME87890.1 - 9.3e-20 70.0 1.4 9.3e-20 70.0 1.0 1.9 2 1 0 2 2 2 1 Ribosomal L29 protein VRP1 PF03538.9 EME87890.1 - 0.0066 15.5 0.1 0.007 15.4 0.0 1.1 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein SPATA24 PF15175.1 EME87890.1 - 0.045 13.4 4.8 0.059 13.0 3.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF4272 PF14094.1 EME87890.1 - 0.06 12.3 0.5 0.071 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) CmcH_NodU PF02543.10 EME87890.1 - 0.075 12.1 0.2 0.097 11.7 0.2 1.2 1 0 0 1 1 1 0 Carbamoyltransferase HALZ PF02183.13 EME87890.1 - 0.12 12.0 4.3 0.72 9.6 0.5 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Prefoldin PF02996.12 EME87890.1 - 0.17 11.5 3.6 0.64 9.6 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.1 EME87890.1 - 0.47 10.7 5.2 0.17 12.1 1.9 1.6 1 1 0 1 1 1 0 Snapin/Pallidin CorA PF01544.13 EME87890.1 - 0.72 8.8 2.6 0.64 9.0 1.1 1.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Siah-Interact_N PF09032.6 EME87890.1 - 3.3 7.8 7.9 1.2 9.2 1.0 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal Exonuc_VII_L PF02601.10 EME87890.1 - 5.2 6.1 7.7 12 5.0 5.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit FliT PF05400.8 EME87890.1 - 5.9 7.3 8.4 1.3 9.5 0.4 2.3 2 1 0 2 2 2 0 Flagellar protein FliT GMC_oxred_N PF00732.14 EME87892.1 - 2.7e-30 105.5 0.0 9.2e-21 74.2 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 EME87892.1 - 1.7e-27 96.4 0.0 2.8e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EME87892.1 - 2.6e-06 27.3 0.0 6.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EME87892.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME87892.1 - 0.00032 19.6 0.0 0.0011 17.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EME87892.1 - 0.0014 17.6 0.0 0.0042 16.0 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME87892.1 - 0.0035 16.3 0.1 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EME87892.1 - 0.0035 16.4 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EME87892.1 - 0.036 14.1 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME87892.1 - 0.055 12.3 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EME87892.1 - 0.072 11.5 0.1 0.099 11.0 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EME87892.1 - 0.086 11.8 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EME87892.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ATP-synt_10 PF05176.9 EME87893.1 - 1e-71 241.2 0.0 1.1e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein HYR PF02494.11 EME87896.1 - 0.027 14.4 0.1 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 HYR domain Syja_N PF02383.13 EME87897.1 - 1.3e-93 313.2 0.5 1.3e-93 313.2 0.3 1.4 2 0 0 2 2 2 1 SacI homology domain Ras PF00071.17 EME87898.1 - 1.4e-59 200.1 0.5 1.6e-59 199.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME87898.1 - 1.5e-19 70.6 0.1 2.7e-19 69.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME87898.1 - 8e-15 54.5 0.0 9.8e-15 54.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME87898.1 - 3.3e-08 33.1 0.1 6e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME87898.1 - 3.8e-07 29.5 0.0 4.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME87898.1 - 3.3e-06 27.0 0.0 4.9e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EME87898.1 - 0.026 14.6 0.1 1 9.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EME87898.1 - 0.028 13.6 0.3 0.12 11.5 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME87898.1 - 0.053 13.4 0.8 0.15 12.0 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EME87898.1 - 0.058 12.6 0.1 0.15 11.2 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Mito_fiss_Elm1 PF06258.6 EME87898.1 - 0.07 12.0 0.1 0.097 11.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 AAA_14 PF13173.1 EME87898.1 - 0.077 12.8 0.1 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2461 PF09365.5 EME87899.1 - 2.7e-47 160.9 0.1 3.6e-45 153.9 0.1 2.3 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF1413 PF07205.6 EME87899.1 - 0.063 12.8 0.2 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Zn_clus PF00172.13 EME87900.1 - 6.1e-08 32.4 6.7 9.2e-08 31.8 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.8 EME87901.1 - 1.7e-23 82.1 4.2 2.7e-23 81.4 2.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Imm45 PF15603.1 EME87901.1 - 0.093 12.8 0.6 1.9 8.6 0.0 3.1 4 0 0 4 4 4 0 Immunity protein 45 Sgf11 PF08209.6 EME87902.1 - 3e-11 42.4 0.2 3e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EME87902.1 - 0.0099 15.5 1.7 0.029 14.0 1.2 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type SieB PF14163.1 EME87903.1 - 0.014 14.9 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Methyltransf_23 PF13489.1 EME87904.1 - 6.3e-16 58.5 0.1 8.4e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME87904.1 - 2.4e-10 40.7 0.0 5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME87904.1 - 6.9e-10 38.7 0.0 1.4e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME87904.1 - 2.5e-09 37.6 0.0 6.1e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME87904.1 - 2.7e-09 37.2 0.0 5.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME87904.1 - 4.4e-08 33.5 0.0 1.5e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME87904.1 - 3.1e-05 23.2 0.0 7.9e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME87904.1 - 0.00028 20.9 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EME87904.1 - 0.0083 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EME87904.1 - 0.013 14.9 0.0 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EME87904.1 - 0.066 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain KGG PF10685.4 EME87904.1 - 0.73 9.8 8.1 6.3 6.8 0.5 2.7 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif BATS PF06968.8 EME87906.1 - 2.4e-25 88.2 0.0 5.3e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EME87906.1 - 4.4e-14 52.9 0.1 1.1e-13 51.7 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily RabGAP-TBC PF00566.13 EME87908.1 - 9.1e-36 123.3 0.1 1.3e-35 122.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 4HBT PF03061.17 EME87909.1 - 2.8e-05 24.1 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EME87909.1 - 0.00038 19.4 0.6 0.00067 18.6 0.4 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EME87909.1 - 0.0064 16.9 0.0 0.008 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1769 PF08588.5 EME87910.1 - 3e-29 100.7 0.9 5.5e-29 99.8 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.15 EME87911.1 - 2.3e-96 322.8 0.0 3.3e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NTP_transferase PF00483.18 EME87913.1 - 2.3e-30 105.7 0.0 3.4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EME87913.1 - 1.9e-10 39.7 6.5 9.5e-07 28.0 0.1 3.7 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EME87913.1 - 2.5e-07 30.9 0.0 4.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2968 PF11180.3 EME87913.1 - 0.0066 15.8 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) IspD PF01128.14 EME87913.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_3 PF13641.1 EME87913.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Hexapep_2 PF14602.1 EME87913.1 - 0.097 12.2 2.3 0.33 10.5 0.1 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase adh_short PF00106.20 EME87914.1 - 4.2e-14 52.8 4.7 1e-12 48.2 3.2 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME87914.1 - 1.5e-07 31.2 0.6 1.3e-05 24.8 0.4 2.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EME87914.1 - 4.4e-05 23.0 0.4 0.00089 18.7 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EME87914.1 - 0.0023 17.7 1.1 0.007 16.1 0.8 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME87914.1 - 0.0064 16.5 0.6 0.019 14.9 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding Amidohydro_2 PF04909.9 EME87914.1 - 0.043 13.3 0.0 0.067 12.7 0.0 1.3 1 1 0 1 1 1 0 Amidohydrolase PIN_4 PF13638.1 EME87915.1 - 0.0014 18.6 0.1 0.0028 17.7 0.1 1.5 1 0 0 1 1 1 1 PIN domain FGGY_C PF02782.11 EME87916.1 - 1.3e-27 96.7 0.0 2.1e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EME87916.1 - 1.1e-20 74.0 0.0 3.5e-12 46.1 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF3074 PF11274.3 EME87917.1 - 1.5e-47 161.6 1.4 1.1e-45 155.5 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3074) CAF-1_p150 PF11600.3 EME87917.1 - 0.00057 19.3 41.6 0.0011 18.3 28.8 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tox-HDC PF15656.1 EME87917.1 - 0.064 13.4 0.3 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Allexi_40kDa PF05549.6 EME87917.1 - 9.2 5.4 10.0 17 4.5 6.9 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein zf-rbx1 PF12678.2 EME87918.1 - 0.0063 16.5 2.7 0.031 14.3 1.9 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger Abhydrolase_5 PF12695.2 EME87919.1 - 5.2e-06 26.2 0.0 6.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME87919.1 - 2.5e-05 24.2 1.2 5.5e-05 23.1 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME87919.1 - 8.6e-05 22.1 0.0 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EME87919.1 - 0.0024 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EME87919.1 - 0.025 14.7 0.5 0.095 12.9 0.0 2.1 3 0 0 3 3 3 0 Thioesterase domain Lipase_3 PF01764.20 EME87919.1 - 0.14 11.7 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF4197 PF13852.1 EME87919.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) DUF2361 PF10153.4 EME87920.1 - 3.7e-32 110.8 2.3 3.7e-32 110.8 1.6 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) IGF2_C PF08365.6 EME87920.1 - 7.3 6.4 7.4 0.59 9.9 0.9 2.3 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide DUF2985 PF11204.3 EME87921.1 - 5.5e-39 131.7 0.8 5.5e-39 131.7 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) SIR2 PF02146.12 EME87923.1 - 1.5e-29 102.9 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF3797 PF12677.2 EME87923.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) EF-hand_6 PF13405.1 EME87924.1 - 3.1e-09 35.9 0.0 3.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EME87924.1 - 1.3e-07 31.6 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME87924.1 - 2.3e-07 29.6 0.0 0.00089 18.3 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EME87924.1 - 8.3e-06 24.9 0.2 0.0033 16.6 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EME87924.1 - 1.7e-05 24.6 0.0 0.054 13.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EME87924.1 - 0.03 13.9 0.0 0.82 9.3 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair DUF566 PF04484.7 EME87924.1 - 8.1 5.8 14.6 11 5.3 10.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Afi1 PF07792.7 EME87925.1 - 4.1e-59 198.7 0.0 9.4e-59 197.5 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EME87925.1 - 9.3e-34 115.5 0.0 1.7e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EME87925.1 - 2e-07 29.8 0.1 0.13 10.7 0.0 4.0 2 2 2 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 EME87925.1 - 0.02 14.2 0.0 0.42 9.8 0.0 3.1 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2347) CLU PF13236.1 EME87926.1 - 2.2e-81 272.5 0.0 3.8e-81 271.7 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EME87926.1 - 1.2e-43 148.9 0.0 5.9e-43 146.7 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EME87926.1 - 6.7e-27 93.2 17.9 1.3e-09 37.8 0.1 3.6 1 1 3 4 4 4 4 Tetratricopeptide repeat CLU_N PF15044.1 EME87926.1 - 6.5e-26 90.3 0.7 2.8e-25 88.2 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EME87926.1 - 1.3e-16 59.8 2.2 0.00012 21.9 0.1 5.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME87926.1 - 0.00034 20.2 5.8 0.43 10.2 2.4 3.2 2 1 1 3 3 3 3 TPR repeat DUF727 PF05303.7 EME87926.1 - 0.00083 19.1 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.1 EME87926.1 - 0.0025 17.4 1.8 1.5 8.7 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME87926.1 - 0.0075 16.0 4.2 0.68 10.0 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME87927.1 - 4e-53 176.9 17.9 5.9e-18 64.2 0.0 6.3 4 2 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 EME87927.1 - 2.7e-47 156.5 17.2 2.3e-10 39.6 0.1 8.5 8 1 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EME87927.1 - 5.1e-43 141.5 17.3 2.2e-07 30.2 0.0 8.9 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EME87927.1 - 5e-32 109.8 13.2 7.9e-08 32.7 1.8 6.1 4 2 2 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.26 EME87927.1 - 2.4e-28 97.6 3.2 8.8e-28 95.8 2.2 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 EME87927.1 - 2.7e-27 92.7 13.4 0.00014 22.1 0.0 8.6 5 3 4 9 9 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 EME87927.1 - 4.3e-25 87.8 18.8 1.3e-07 31.8 0.2 6.3 4 3 2 7 7 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME87927.1 - 4.7e-23 80.9 12.9 2.8e-07 30.3 0.2 6.1 3 2 2 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EME87927.1 - 5.7e-23 79.1 13.2 0.00039 20.4 0.6 8.2 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EME87927.1 - 1e-19 68.6 8.0 0.0027 17.3 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EME87927.1 - 3e-19 67.2 13.4 0.0011 18.5 0.0 8.4 8 2 1 9 9 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EME87927.1 - 7.5e-18 64.4 6.5 1.2e-07 31.7 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EME87927.1 - 5.3e-17 61.4 7.0 0.0001 22.0 0.3 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 EME87927.1 - 1e-15 57.0 16.5 0.015 15.7 0.0 8.3 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 EME87927.1 - 1.2e-09 37.7 10.8 1.2 9.2 0.0 7.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EME87927.1 - 2.1e-09 36.8 3.2 0.27 11.7 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EME87927.1 - 4.5e-08 32.4 9.4 0.084 11.9 0.4 4.5 3 2 0 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.12 EME87927.1 - 3.1e-07 30.8 7.5 0.0097 16.2 0.1 4.6 3 2 2 5 5 5 2 Bacterial transcriptional activator domain NARP1 PF12569.3 EME87927.1 - 2.7e-05 23.1 3.0 0.029 13.1 0.0 3.9 2 2 2 4 4 4 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 EME87927.1 - 4.1e-05 23.6 12.6 0.39 10.8 0.0 5.2 3 3 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME87927.1 - 9.9e-05 22.1 8.5 1.1 9.1 0.0 4.8 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 EME87927.1 - 0.00033 20.4 5.2 5.8 6.7 0.1 5.4 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.4 EME87927.1 - 0.0013 17.9 4.2 8.8 5.6 0.0 4.7 5 0 0 5 5 5 0 SHNi-TPR DUF3808 PF10300.4 EME87927.1 - 0.0027 16.3 0.0 0.016 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) Alkyl_sulf_dimr PF14863.1 EME87927.1 - 0.0045 17.2 6.1 0.77 9.9 0.1 4.4 1 1 3 5 5 5 1 Alkyl sulfatase dimerisation MIT PF04212.13 EME87927.1 - 0.015 15.1 14.7 1.4 8.8 0.1 5.5 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EME87927.1 - 0.03 13.1 1.5 0.35 9.6 0.1 2.5 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RRM_3 PF08777.6 EME87927.1 - 0.046 13.5 0.6 0.14 11.9 0.0 2.1 2 1 0 2 2 1 0 RNA binding motif TPR_21 PF09976.4 EME87927.1 - 0.065 13.1 16.6 2.1 8.2 0.5 5.0 2 2 2 5 5 5 0 Tetratricopeptide repeat DUF3597 PF12200.3 EME87927.1 - 0.068 13.5 0.1 0.068 13.5 0.1 3.2 3 2 0 3 3 1 0 Domain of unknown function (DUF3597) Rapsyn_N PF10579.4 EME87927.1 - 0.13 12.0 0.4 18 5.1 0.0 4.2 2 2 2 4 4 4 0 Rapsyn N-terminal myristoylation and linker region Coatomer_E PF04733.9 EME87927.1 - 0.15 11.2 2.0 6.6 5.8 0.2 2.9 2 1 0 2 2 2 0 Coatomer epsilon subunit Sec5 PF15469.1 EME87927.1 - 0.15 11.7 6.9 4.4 6.9 0.0 4.0 3 1 1 4 4 4 0 Exocyst complex component Sec5 TPR_3 PF07720.7 EME87927.1 - 0.36 10.6 4.1 8.9 6.2 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1542 PF07564.6 EME87927.1 - 0.8 9.7 5.9 0.75 9.8 0.6 3.3 3 1 1 4 4 2 0 Domain of Unknown Function (DUF1542) DUF3366 PF11846.3 EME87927.1 - 1.3 8.8 8.5 11 5.8 2.3 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF3366) Sugar_tr PF00083.19 EME87929.1 - 8.9e-105 350.8 23.5 1.1e-104 350.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87929.1 - 4.1e-24 84.9 34.0 2e-16 59.6 8.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-BED PF02892.10 EME87930.1 - 0.0018 17.9 2.6 0.0037 16.9 1.8 1.5 1 0 0 1 1 1 1 BED zinc finger zf-H2C2_2 PF13465.1 EME87930.1 - 0.018 15.3 2.1 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME87930.1 - 0.071 13.4 3.7 0.22 11.9 2.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EME87930.1 - 1.1 9.7 8.9 0.096 13.0 2.6 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Herpes_LMP2 PF07415.6 EME87930.1 - 1.9 6.9 3.3 2.9 6.3 2.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Sulfotransfer_3 PF13469.1 EME87932.1 - 4.1e-05 24.5 0.5 4.1e-05 24.5 0.3 2.3 2 0 0 2 2 2 1 Sulfotransferase family Glyco_transf_90 PF05686.7 EME87933.1 - 2.1e-26 92.5 0.1 3e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EME87933.1 - 4.6e-05 23.6 0.1 0.00031 20.9 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 AATase PF07247.7 EME87935.1 - 0.0031 16.1 0.0 0.0055 15.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol acetyltransferase MFS_1 PF07690.11 EME87936.1 - 1.7e-12 46.7 23.9 2.3e-12 46.3 16.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_2 PF00890.19 EME87937.1 - 8.7e-104 347.6 5.7 7e-97 324.8 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Succ_DH_flav_C PF02910.15 EME87937.1 - 3.5e-46 156.2 2.1 5.5e-46 155.5 1.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EME87937.1 - 1.2e-06 28.6 0.1 3.3e-05 23.8 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME87937.1 - 2e-05 23.8 0.5 0.017 14.1 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EME87937.1 - 0.00016 20.7 0.5 0.15 10.8 0.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EME87937.1 - 0.007 15.4 0.1 0.015 14.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME87937.1 - 0.012 14.5 0.6 0.27 10.0 0.3 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME87937.1 - 0.36 10.8 4.3 6.2 6.8 0.8 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Rotamase_3 PF13616.1 EME87938.1 - 3e-18 66.1 0.1 6.4e-18 65.1 0.1 1.6 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase PF00639.16 EME87938.1 - 1.8e-17 63.8 0.1 3.7e-17 62.8 0.0 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EME87938.1 - 7e-07 29.9 0.1 8.5e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.1 EME87939.1 - 2.3e-16 60.1 0.0 8.1e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EME87939.1 - 1.2e-07 31.9 0.1 3.5e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sod_Fe_C PF02777.13 EME87940.1 - 4.8e-37 126.0 0.2 1.2e-36 124.7 0.1 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EME87940.1 - 2.4e-29 101.4 1.8 4.6e-29 100.5 1.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-C2H2 PF00096.21 EME87942.1 - 1e-07 31.8 16.4 5.2e-06 26.4 1.9 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME87942.1 - 3.3e-06 27.0 3.3 3.3e-06 27.0 2.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME87942.1 - 0.00027 21.0 15.1 0.00027 21.0 0.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME87942.1 - 0.00061 19.8 0.7 0.00061 19.8 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EME87942.1 - 0.28 11.6 10.8 0.079 13.3 1.9 2.6 1 1 1 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 EME87942.1 - 0.58 10.4 3.2 0.62 10.3 0.4 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EME87942.1 - 0.7 10.0 7.9 0.35 10.9 0.7 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EME87942.1 - 1.8 8.7 9.3 1.2 9.3 0.2 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EME87942.1 - 2.8 8.3 6.2 1.6 9.0 1.1 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Sugar_tr PF00083.19 EME87943.1 - 2e-82 277.1 20.8 3.7e-80 269.7 14.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87943.1 - 2.6e-28 98.7 20.1 2.6e-28 98.7 14.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME87943.1 - 7e-05 21.4 17.8 0.012 13.9 2.2 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EME87943.1 - 0.005 15.0 1.7 0.005 15.0 1.1 2.1 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) PhyH PF05721.8 EME87944.1 - 2.4e-07 30.9 0.0 8.3e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EME87944.1 - 2.9e-05 22.7 0.0 0.011 14.1 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) p450 PF00067.17 EME87945.1 - 3.2e-60 203.9 0.0 4.1e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.22 EME87946.1 - 2.2e-49 167.2 0.1 5.1e-27 94.8 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME87946.1 - 5.4e-18 65.9 0.0 4.6e-08 33.3 0.0 3.6 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EME87946.1 - 1.8e-13 50.2 0.0 0.0002 20.6 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME87946.1 - 6.7e-08 31.9 0.3 0.0038 16.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EME87946.1 - 7.6e-08 32.9 0.0 0.00044 20.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 EME87946.1 - 4.6e-07 29.4 0.2 1e-06 28.3 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 EME87946.1 - 7.4e-07 28.4 0.1 0.004 16.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EME87946.1 - 1.1e-06 28.5 0.0 0.013 15.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EME87946.1 - 3.6e-06 26.6 1.0 0.46 9.8 0.0 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 EME87946.1 - 1e-05 26.3 0.0 0.037 14.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EME87946.1 - 1.8e-05 23.9 0.0 0.84 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain Miro PF08477.8 EME87946.1 - 1.9e-05 25.1 0.0 0.075 13.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EME87946.1 - 2.2e-05 24.6 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EME87946.1 - 6.2e-05 23.0 0.0 0.0046 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EME87946.1 - 0.00011 21.9 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EME87946.1 - 0.00021 21.1 0.0 0.66 9.9 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EME87946.1 - 0.00021 20.1 0.4 0.14 10.8 0.0 2.4 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EME87946.1 - 0.00025 21.1 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EME87946.1 - 0.00031 20.2 0.0 0.2 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME87946.1 - 0.00034 20.5 0.0 0.62 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EME87946.1 - 0.00076 19.3 1.6 0.15 11.8 0.0 3.1 4 0 0 4 4 2 1 Domain of unknown function DUF87 NACHT PF05729.7 EME87946.1 - 0.0012 18.5 0.2 0.87 9.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EME87946.1 - 0.0015 18.7 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EME87946.1 - 0.0015 18.4 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT PF02985.17 EME87946.1 - 0.0017 18.2 0.0 35 4.8 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.1 EME87946.1 - 0.002 18.3 2.0 0.096 12.9 0.1 3.5 2 1 2 4 4 3 2 HEAT repeats AAA_18 PF13238.1 EME87946.1 - 0.0025 18.1 0.4 0.38 11.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 EME87946.1 - 0.0026 17.2 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EME87946.1 - 0.004 16.1 0.1 0.61 8.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EME87946.1 - 0.0043 16.5 0.1 0.97 8.8 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_13 PF13166.1 EME87946.1 - 0.0065 14.9 0.0 2.2 6.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EME87946.1 - 0.0066 16.0 0.1 1.6 8.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 EME87946.1 - 0.0098 15.7 0.0 0.51 10.1 0.0 2.7 2 1 0 2 2 2 1 Dynamin family Arch_ATPase PF01637.13 EME87946.1 - 0.01 15.5 0.4 3.9 7.0 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase Alginate_lyase2 PF08787.6 EME87946.1 - 0.014 15.0 0.1 0.032 13.8 0.0 1.6 2 0 0 2 2 1 0 Alginate lyase cobW PF02492.14 EME87946.1 - 0.018 14.5 0.0 8.8 5.7 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EME87946.1 - 0.018 14.0 0.0 5.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Septin Adaptin_N PF01602.15 EME87946.1 - 0.027 12.8 0.1 0.047 11.9 0.1 1.3 1 0 0 1 1 1 0 Adaptin N terminal region AAA_16 PF13191.1 EME87946.1 - 0.032 14.2 0.0 2.1 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain HEAT_EZ PF13513.1 EME87946.1 - 0.033 14.6 4.0 17 6.0 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat ATP-synt_ab PF00006.20 EME87946.1 - 0.048 13.1 0.2 11 5.4 0.0 3.3 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EME87946.1 - 0.086 12.4 0.2 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MutS_V PF00488.16 EME87946.1 - 0.13 11.6 0.5 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 MutS domain V DUF3584 PF12128.3 EME87946.1 - 0.63 7.2 5.7 2.5 5.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Ribosomal_L24e PF01246.15 EME87948.1 - 3.5e-28 97.2 0.5 3.5e-28 97.2 0.4 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e GlcNAc PF11397.3 EME87948.1 - 0.34 9.9 4.5 0.44 9.6 3.1 1.0 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) WTX PF09422.5 EME87948.1 - 0.49 9.2 8.5 0.58 9.0 5.9 1.0 1 0 0 1 1 1 0 WTX protein Thioredoxin PF00085.15 EME87949.1 - 2.6e-06 27.0 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3074 PF11274.3 EME87950.1 - 1.9e-37 128.6 0.0 2.8e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) MFS_1 PF07690.11 EME87951.1 - 4.3e-05 22.3 3.4 4.3e-05 22.3 2.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ACOX PF01756.14 EME87952.1 - 5.5e-33 113.9 0.1 1.7e-32 112.2 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EME87952.1 - 1.2e-24 87.0 0.4 2.6e-24 85.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EME87952.1 - 1.2e-09 37.4 0.0 4.7e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EME87952.1 - 5e-05 23.4 0.4 0.00032 20.8 0.3 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EME87952.1 - 0.0061 17.1 0.1 0.03 14.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain AMP-binding PF00501.23 EME87953.1 - 1.8e-62 211.0 0.0 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME87953.1 - 8.5e-15 55.4 0.0 3.1e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SAP PF02037.22 EME87954.1 - 8.2e-10 37.9 0.5 1.8e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 SAP domain DUF773 PF05600.7 EME87954.1 - 0.12 11.0 2.1 0.16 10.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF773) ECH PF00378.15 EME87955.1 - 1.8e-23 82.9 0.0 2.2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family p450 PF00067.17 EME87956.1 - 1.9e-58 198.0 0.0 2.5e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1993 PF09351.5 EME87957.1 - 0.039 13.8 0.1 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF1654 PF07867.6 EME87957.1 - 0.092 12.1 0.4 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) FliJ PF02050.11 EME87957.1 - 2.4 8.2 10.3 4.5 7.3 7.2 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein Peptidase_C50 PF03568.12 EME87958.1 - 1.6e-98 329.8 0.0 1.3e-97 326.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EME87958.1 - 0.24 11.3 19.2 0.12 12.3 0.3 5.9 5 1 2 7 7 7 0 Tetratricopeptide repeat MFS_1 PF07690.11 EME87960.1 - 5.6e-22 77.9 66.1 4.1e-16 58.6 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-H2C2_2 PF13465.1 EME87962.1 - 0.02 15.1 6.3 1.2 9.5 1.2 3.6 3 1 0 3 3 3 0 Zinc-finger double domain Sporozoite_P67 PF05642.6 EME87962.1 - 0.087 10.6 5.1 0.16 9.7 3.6 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2_4 PF13894.1 EME87962.1 - 0.093 13.1 0.0 0.093 13.1 0.0 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EME87962.1 - 0.29 11.5 21.9 0.8 10.1 0.1 5.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EME87962.1 - 0.91 9.5 4.6 0.19 11.7 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger PHD PF00628.24 EME87964.1 - 3.1e-09 36.3 10.6 7.3e-09 35.1 7.4 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EME87964.1 - 0.00029 20.0 4.0 0.00073 18.7 2.8 1.7 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EME87964.1 - 1.3 8.7 10.4 0.098 12.3 3.6 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FPN1 PF06963.7 EME87965.1 - 1.2e-118 396.2 15.0 1.5e-118 395.9 10.4 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DUF4066 PF13278.1 EME87965.1 - 0.03 13.6 0.4 0.47 9.7 0.0 2.3 1 1 1 2 2 2 0 Putative amidotransferase DUF1771 PF08590.5 EME87967.1 - 3.2e-16 59.0 16.6 3.2e-16 59.0 11.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EME87967.1 - 8e-16 58.0 2.1 8.2e-16 57.9 0.1 2.0 2 0 0 2 2 2 1 Smr domain Dispanin PF04505.7 EME87967.1 - 0.35 10.4 1.5 0.75 9.3 1.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein PspA_IM30 PF04012.7 EME87967.1 - 0.45 9.8 11.7 1.4 8.1 5.5 2.1 2 0 0 2 2 2 0 PspA/IM30 family DDRGK PF09756.4 EME87967.1 - 2.3 7.5 8.6 3.8 6.8 5.9 1.4 1 1 0 1 1 1 0 DDRGK domain AIM24 PF01987.12 EME87968.1 - 1.3e-42 145.7 0.8 1.6e-42 145.4 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Scm3 PF10384.4 EME87968.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 GCS PF03074.11 EME87969.1 - 2.3e-153 510.6 0.0 3.1e-153 510.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.22 EME87970.1 - 8.8e-15 53.7 5.2 1.8e-14 52.8 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EME87970.1 - 0.26 11.3 1.9 0.54 10.2 1.3 1.5 1 0 0 1 1 1 0 zinc-finger Sigma70_r4_2 PF08281.7 EME87972.1 - 0.024 14.0 0.2 0.094 12.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DUF837 PF05769.6 EME87972.1 - 0.035 13.6 4.0 0.048 13.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Syntaxin PF00804.20 EME87972.1 - 0.16 12.1 3.3 0.16 12.1 1.6 1.5 1 1 1 2 2 2 0 Syntaxin Herpes_BLRF2 PF05812.7 EME87972.1 - 2.7 7.8 5.2 5.6 6.8 0.2 2.6 1 1 0 2 2 2 0 Herpesvirus BLRF2 protein Atg14 PF10186.4 EME87972.1 - 2.9 6.7 9.4 1 8.2 1.4 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 EME87972.1 - 4.4 7.6 6.9 3.3 8.0 3.0 2.1 1 1 1 2 2 2 0 Snapin/Pallidin TPR_MLP1_2 PF07926.7 EME87972.1 - 6.1 6.6 11.4 98 2.6 7.9 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1325 PF07039.6 EME87973.1 - 1.3e-22 79.8 0.0 2.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain ARD PF03079.9 EME87973.1 - 0.026 14.4 0.2 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 ARD/ARD' family PMI_typeI PF01238.16 EME87974.1 - 1e-142 475.5 0.0 1.2e-142 475.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EME87974.1 - 0.13 11.7 0.0 0.72 9.3 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Arf PF00025.16 EME87975.1 - 1.3e-73 245.9 0.1 1.6e-73 245.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME87975.1 - 9.2e-13 47.8 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME87975.1 - 2.3e-12 46.6 0.0 2.6e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME87975.1 - 4e-12 45.5 1.5 1.2e-08 34.1 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME87975.1 - 7.2e-11 41.6 0.0 8.4e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME87975.1 - 3.6e-08 33.9 0.0 5.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME87975.1 - 0.00011 22.1 0.1 0.00036 20.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EME87975.1 - 0.019 14.0 0.2 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Glyco_transf_8 PF01501.15 EME87976.1 - 1.1e-22 80.5 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 EME87977.1 - 2.1e-58 194.0 0.1 1.2e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Anp1 PF03452.9 EME87978.1 - 7.3e-110 366.3 0.0 9.3e-110 366.0 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EME87978.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 G-alpha PF00503.15 EME87981.1 - 3.6e-115 384.7 0.6 4.4e-115 384.4 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EME87981.1 - 2.1e-13 49.8 4.7 2.5e-09 36.5 0.0 3.0 3 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME87981.1 - 9.9e-05 21.5 0.6 0.017 14.2 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME87981.1 - 0.009 15.4 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2985 PF11204.3 EME87981.1 - 0.017 14.8 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) Miro PF08477.8 EME87981.1 - 0.034 14.6 0.1 7.3 7.1 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EME87981.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EME87981.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family SET PF00856.23 EME87982.1 - 9e-12 45.5 0.4 9.6e-09 35.7 0.0 2.6 3 0 0 3 3 3 2 SET domain Hexapep PF00132.19 EME87983.1 - 2.2e-11 42.7 11.5 1e-06 27.9 1.0 4.4 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EME87983.1 - 6e-09 35.3 10.3 2.6e-05 23.7 1.0 4.7 4 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase PI-PLC-X PF00388.14 EME87984.1 - 2.2e-13 49.8 0.0 3e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Meth_synt_2 PF01717.13 EME87985.1 - 5e-16 58.5 0.0 3.2e-12 46.0 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EME87985.1 - 1.3e-05 24.6 0.0 0.017 14.3 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain HAD_2 PF13419.1 EME87986.1 - 6.8e-16 58.9 0.3 4.2e-15 56.4 0.2 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME87986.1 - 0.00028 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like FAA_hydrolase PF01557.13 EME87987.1 - 5e-08 32.6 0.0 5.8e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hira PF07569.6 EME87988.1 - 2.5e-81 272.0 0.0 4.8e-81 271.1 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EME87988.1 - 9.4e-41 136.2 18.7 5e-08 32.5 0.0 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 EME87988.1 - 5.1e-12 45.0 0.7 9.9e-12 44.0 0.5 1.5 1 0 0 1 1 1 1 HIRA B motif IKI3 PF04762.7 EME87988.1 - 0.0025 15.7 0.0 0.12 10.2 0.0 2.4 2 0 0 2 2 2 2 IKI3 family Scs3p PF10261.4 EME87989.1 - 8.2e-67 224.7 4.9 1e-66 224.4 3.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Response_reg PF00072.19 EME87990.1 - 5.5e-24 84.3 0.4 1.5e-23 82.9 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EME87990.1 - 2.5e-20 72.2 0.0 4.6e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EME87990.1 - 8.7e-09 35.2 0.0 2.1e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EME87990.1 - 0.026 14.1 0.1 0.089 12.4 0.0 2.0 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PX PF00787.19 EME87991.1 - 2.9e-15 56.0 0.0 5.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EME87991.1 - 4.9e-10 38.9 4.8 4.9e-10 38.9 3.3 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin-6_N PF09177.6 EME87991.1 - 0.015 15.7 0.1 0.015 15.7 0.1 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF479 PF04336.7 EME87991.1 - 0.05 13.7 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF479 cIII PF08134.6 EME87991.1 - 0.059 12.9 2.3 0.43 10.2 0.0 2.8 3 0 0 3 3 3 0 cIII protein family RRM_1 PF00076.17 EME87992.1 - 3.5e-19 68.1 0.0 7.6e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME87992.1 - 5.4e-14 51.9 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME87992.1 - 5.2e-07 29.4 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Barttin PF15462.1 EME87992.1 - 0.023 14.3 3.0 0.035 13.7 2.1 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Zip PF02535.17 EME87992.1 - 2.5 7.0 8.4 3.7 6.4 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dynamin_N PF00350.18 EME87993.1 - 7.3e-18 64.9 0.0 3.4e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EME87993.1 - 3.4e-11 42.4 0.0 5.1e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 EME87993.1 - 0.00061 20.2 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME87993.1 - 0.00098 19.0 0.0 0.02 14.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EME87993.1 - 0.049 13.1 0.1 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EME87993.1 - 0.095 12.6 0.2 0.43 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Ribonuclease_3 PF00636.21 EME87995.1 - 5.9e-40 136.2 0.0 3e-21 75.9 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EME87995.1 - 3.9e-25 88.2 0.0 2.8e-13 49.9 0.0 3.8 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EME87995.1 - 1.8e-19 69.8 0.0 3.9e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME87995.1 - 3.3e-16 58.9 0.1 9.5e-16 57.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EME87995.1 - 8e-16 57.5 0.0 2.3e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 EME87995.1 - 5.5e-11 42.6 0.0 3.7e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3638 PF12340.3 EME87995.1 - 0.0043 16.0 0.0 0.0072 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) AAA_10 PF12846.2 EME87995.1 - 0.023 14.1 0.1 1.3 8.3 0.0 3.2 3 1 0 3 3 3 0 AAA-like domain dsrm PF00035.20 EME87995.1 - 0.057 14.0 0.2 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif T2SE PF00437.15 EME87995.1 - 0.061 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MFS_1 PF07690.11 EME87996.1 - 3e-30 105.1 37.5 3e-30 105.1 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EME87996.1 - 0.055 11.5 4.1 0.34 8.9 2.8 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EME87997.1 - 1.1e-76 258.3 38.7 2e-75 254.0 26.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME87997.1 - 1.7e-25 89.4 60.0 1.7e-21 76.3 22.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME87997.1 - 0.00077 17.9 33.7 0.0022 16.4 4.9 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Gly-zipper_OmpA PF13436.1 EME87998.1 - 0.013 15.1 1.9 0.017 14.7 0.1 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Aldo_ket_red PF00248.16 EME88000.1 - 5.5e-68 228.8 0.0 7e-68 228.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pantoate_ligase PF02569.10 EME88000.1 - 0.15 10.7 0.0 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase Alpha-amylase PF00128.19 EME88001.1 - 5.7e-95 318.3 0.0 1.3e-94 317.1 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EME88001.1 - 0.00087 18.2 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme F-box-like PF12937.2 EME88003.1 - 2.2e-05 24.0 0.2 4.7e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like TruB_C PF09142.6 EME88003.1 - 0.0018 17.9 0.0 9.6 5.9 0.0 4.0 4 0 0 4 4 4 2 tRNA Pseudouridine synthase II, C terminal F-box PF00646.28 EME88003.1 - 0.0058 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain CIA30 PF08547.7 EME88004.1 - 2.7e-38 131.3 0.0 3.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Abhydrolase_9 PF10081.4 EME88005.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Pectinesterase PF01095.14 EME88007.1 - 4.8e-50 169.8 6.6 6.2e-50 169.4 4.5 1.0 1 0 0 1 1 1 1 Pectinesterase HARE-HTH PF05066.8 EME88007.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain FAD_binding_4 PF01565.18 EME88008.1 - 7.8e-19 67.5 0.0 1.4e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Cpn60_TCP1 PF00118.19 EME88009.1 - 2.3e-111 372.8 3.1 2.6e-111 372.6 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EME88009.1 - 0.038 13.2 0.8 0.15 11.2 0.2 2.1 2 0 0 2 2 2 0 DeoC/LacD family aldolase AAA PF00004.24 EME88010.1 - 1.2e-40 138.8 0.0 2e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME88010.1 - 4e-06 27.0 0.1 0.0006 19.9 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EME88010.1 - 3.4e-05 23.5 0.1 0.0003 20.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EME88010.1 - 0.0002 21.4 0.1 0.0015 18.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EME88010.1 - 0.00038 20.3 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EME88010.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EME88010.1 - 0.0039 17.9 0.1 0.013 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME88010.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EME88010.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EME88010.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME88010.1 - 0.018 15.2 0.1 0.13 12.4 0.0 2.4 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 EME88010.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME88010.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EME88010.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EME88010.1 - 0.069 13.2 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EME88010.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EME88010.1 - 0.09 12.3 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 EME88010.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) IstB_IS21 PF01695.12 EME88010.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EME88010.1 - 0.12 12.6 0.4 0.37 11.1 0.0 2.0 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EME88010.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EME88010.1 - 0.14 11.5 0.2 0.45 9.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 EME88011.1 - 4.1e-62 210.5 0.0 5e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EME88011.1 - 8.6e-07 29.2 0.0 2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME88011.1 - 7.9e-06 26.0 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME88011.1 - 4.3e-05 23.1 0.1 0.00014 21.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EME88011.1 - 0.00015 22.5 0.0 0.00035 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME88011.1 - 0.0024 17.4 0.1 0.0063 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME88011.1 - 0.0031 17.5 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 EME88011.1 - 0.0031 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EME88011.1 - 0.0096 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EME88011.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME88011.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EME88011.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EME88011.1 - 0.025 14.3 0.1 0.053 13.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EME88011.1 - 0.025 14.4 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME88011.1 - 0.027 13.5 0.0 0.063 12.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EME88011.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EME88011.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 EME88011.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EME88011.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EME88011.1 - 0.11 12.1 0.7 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 EME88011.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit 2OG-FeII_Oxy_2 PF13532.1 EME88012.1 - 1e-29 103.7 0.0 2.2e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFB_NFYA PF02045.10 EME88013.1 - 1.3e-17 64.0 2.5 2.1e-17 63.3 1.8 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_L37 PF08561.5 EME88014.1 - 4.4e-26 90.2 3.9 1.3e-24 85.5 2.7 2.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Pol_alpha_B_N PF08418.5 EME88014.1 - 0.012 15.2 4.9 0.018 14.5 3.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_capsid PF06112.6 EME88014.1 - 0.17 11.9 8.7 1.1 9.2 5.4 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Glyco_hydro_16 PF00722.16 EME88016.1 - 4e-43 146.8 4.7 7.3e-43 145.9 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_8 PF01501.15 EME88017.1 - 2.6e-17 63.0 0.0 7.6e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EME88017.1 - 0.0054 16.5 0.1 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EME88017.1 - 0.021 14.2 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Methyltransf_11 PF08241.7 EME88018.1 - 4.5e-14 52.7 0.0 5.4e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME88018.1 - 2.1e-08 34.5 0.0 1.5e-07 31.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME88018.1 - 2.3e-07 30.1 0.0 4.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EME88018.1 - 4.1e-06 26.4 0.0 7.8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME88018.1 - 4.7e-06 26.8 0.0 2.1e-05 24.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME88018.1 - 1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME88018.1 - 0.0018 18.8 0.0 0.0061 17.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EME88018.1 - 0.017 14.2 0.0 0.19 10.8 0.0 2.2 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EME88018.1 - 0.075 12.2 0.0 0.32 10.1 0.0 2.1 3 0 0 3 3 3 0 O-methyltransferase MFS_1 PF07690.11 EME88019.1 - 2.7e-38 131.6 43.9 3.9e-37 127.7 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME88019.1 - 2.1e-07 29.9 35.7 6e-07 28.3 24.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter zf-Di19 PF05605.7 EME88021.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding VHS PF00790.14 EME88023.1 - 3.3e-19 68.9 0.0 7.7e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EME88023.1 - 6.9e-09 35.5 0.5 1.6e-08 34.4 0.3 1.6 1 0 0 1 1 1 1 GAT domain MLANA PF14991.1 EME88024.1 - 0.27 11.2 2.6 1.6 8.7 1.8 2.4 1 0 0 1 1 1 0 Protein melan-A DUF1772 PF08592.6 EME88025.1 - 0.062 13.0 0.0 0.077 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) TauD PF02668.11 EME88026.1 - 3.3e-56 190.8 0.5 4e-56 190.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EME88026.1 - 0.0072 16.8 0.1 0.079 13.4 0.0 2.3 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily BRICHOS PF04089.9 EME88027.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 BRICHOS domain ATP-synt_ab PF00006.20 EME88028.1 - 1e-60 204.9 0.0 1.4e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EME88028.1 - 1e-14 54.9 0.7 1.8e-14 54.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EME88028.1 - 6.5e-13 48.6 0.7 1.5e-12 47.5 0.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EME88028.1 - 0.00015 21.5 0.2 0.00036 20.3 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain LIM_bind PF01803.11 EME88029.1 - 4.1e-42 143.9 0.1 4.1e-42 143.9 0.1 5.0 3 1 1 4 4 4 1 LIM-domain binding protein AMP-binding PF00501.23 EME88030.1 - 4.1e-63 213.2 0.0 5.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME88030.1 - 1.9e-12 47.9 0.0 2.3e-11 44.4 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DAHP_synth_2 PF01474.11 EME88031.1 - 1.4e-191 636.6 0.0 1.6e-191 636.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Herpes_UL25 PF01499.11 EME88031.1 - 0.043 12.1 0.0 0.062 11.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4463 PF14703.1 EME88031.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) BRCT PF00533.21 EME88033.1 - 0.002 18.2 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EME88033.1 - 0.003 17.3 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Phage_int_SAM_3 PF14659.1 EME88033.1 - 0.14 12.4 0.0 7.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain FMN_dh PF01070.13 EME88034.1 - 4.9e-131 436.8 0.0 5.7e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EME88034.1 - 6.1e-08 31.9 0.3 1.7e-07 30.4 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EME88034.1 - 2.5e-07 29.9 0.0 4.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EME88034.1 - 2e-05 23.9 0.0 0.0002 20.7 0.0 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EME88034.1 - 3.7e-05 23.0 1.9 4.1e-05 22.8 0.7 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EME88034.1 - 0.0027 16.8 0.4 0.048 12.7 0.0 2.2 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EME88034.1 - 0.005 15.8 0.0 0.017 14.0 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.14 EME88034.1 - 0.017 14.2 0.1 1.7 7.7 0.0 2.7 2 1 1 3 3 3 0 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 EME88034.1 - 0.16 11.2 0.2 4.9 6.3 0.0 2.1 1 1 1 2 2 2 0 PcrB family Pyr_redox_3 PF13738.1 EME88035.1 - 3.6e-24 85.9 0.0 2.4e-21 76.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME88035.1 - 2.2e-15 55.8 0.1 8.9e-15 53.8 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME88035.1 - 3.1e-12 46.0 0.2 3.4e-08 32.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME88035.1 - 2e-07 30.9 0.0 4.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME88035.1 - 6e-07 28.6 0.2 0.0012 17.7 0.1 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EME88035.1 - 0.00013 21.8 0.3 0.053 13.2 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME88035.1 - 0.0041 17.0 0.0 0.95 9.3 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EME88035.1 - 0.0046 17.0 0.0 0.24 11.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EME88035.1 - 0.025 13.4 0.1 0.38 9.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EME88035.1 - 0.035 13.0 0.0 3 6.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EME88035.1 - 0.045 12.2 0.1 8.6 4.7 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 EME88035.1 - 0.08 11.9 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EME88035.1 - 0.099 13.0 0.1 2.8 8.4 0.1 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME88035.1 - 0.12 11.4 0.1 0.25 10.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Aldo_ket_red PF00248.16 EME88036.1 - 1.2e-46 158.8 0.0 1.4e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IF4E PF01652.13 EME88038.1 - 2.2e-56 189.9 1.1 2.7e-56 189.6 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4098 PF13345.1 EME88039.1 - 2.9e-05 23.9 3.9 0.65 9.9 0.3 5.3 4 1 1 5 5 5 3 Domain of unknown function (DUF4098) Sec39 PF08314.6 EME88040.1 - 4.1e-163 544.0 0.0 5.1e-163 543.7 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 NAD_binding_10 PF13460.1 EME88041.1 - 1.2e-10 41.7 0.2 1.4e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EME88041.1 - 6.4e-07 28.1 0.0 7.9e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 HIM1 NAD_binding_4 PF07993.7 EME88041.1 - 1.6e-05 24.0 0.0 0.063 12.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 EME88041.1 - 0.00029 20.3 0.0 0.0038 16.6 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EME88041.1 - 0.0015 18.8 0.0 0.0054 17.0 0.0 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TraC PF07820.7 EME88041.1 - 0.014 15.5 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 TraC-like protein DUF1471 PF07338.8 EME88041.1 - 0.022 14.3 0.1 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) OKR_DC_1_N PF03709.10 EME88042.1 - 0.096 12.7 0.0 6.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain 2-Hacid_dh_C PF02826.14 EME88043.1 - 2e-55 186.6 1.4 2.8e-55 186.2 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EME88043.1 - 3.8e-35 120.2 1.1 4.2e-35 120.0 0.2 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EME88043.1 - 0.003 17.4 0.8 0.0062 16.3 0.1 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EME88043.1 - 0.0092 15.8 1.0 0.015 15.1 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.16 EME88043.1 - 0.025 14.1 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_C PF03720.10 EME88043.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_7 PF13241.1 EME88043.1 - 0.054 13.7 0.5 4.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding Cu-oxidase_3 PF07732.10 EME88044.1 - 5.3e-40 135.8 5.2 1.4e-39 134.4 1.7 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME88044.1 - 9.1e-36 122.4 9.7 8.5e-31 106.3 0.1 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EME88044.1 - 9.5e-34 116.6 0.3 2.4e-33 115.2 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase Glyco_hydro_16 PF00722.16 EME88045.1 - 4e-08 32.7 0.0 1.3e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 CTP_transf_2 PF01467.21 EME88046.1 - 3.4e-28 98.6 0.0 4.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Gp37_Gp68 PF07505.6 EME88046.1 - 0.024 13.7 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Glyoxalase PF00903.20 EME88047.1 - 1.3e-37 128.6 1.2 1.3e-17 63.9 0.2 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EME88047.1 - 5.2e-32 110.6 0.1 1.3e-15 57.9 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EME88047.1 - 1.8e-23 82.6 0.7 1.9e-10 40.7 0.0 3.7 2 2 1 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EME88047.1 - 9.3e-11 41.9 0.1 2.7e-05 24.1 0.0 2.8 1 1 1 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EME88047.1 - 0.0066 16.1 0.4 0.39 10.3 0.0 2.3 2 0 0 2 2 2 1 CppA N-terminal Methyltransf_25 PF13649.1 EME88047.1 - 0.026 14.9 0.3 2.7 8.3 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain MoaF PF10703.4 EME88047.1 - 0.028 13.5 0.1 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F DX PF01666.12 EME88047.1 - 0.06 13.7 0.2 0.34 11.3 0.1 2.1 2 0 0 2 2 2 0 DX module PRT_C PF08372.5 EME88047.1 - 0.14 11.6 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal p450 PF00067.17 EME88048.1 - 8.9e-76 255.2 0.0 1.1e-75 254.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 EME88049.1 - 9.2e-13 47.8 0.3 4.4e-12 45.5 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.13 EME88050.1 - 1.3e-06 28.1 9.5 2e-06 27.5 6.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME88050.1 - 2.2e-06 26.7 0.0 3.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40_alt PF14077.1 EME88050.1 - 0.13 11.8 0.3 0.31 10.7 0.2 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif MAPEG PF01124.13 EME88051.1 - 9.7e-12 44.6 4.2 1.2e-11 44.3 2.9 1.1 1 0 0 1 1 1 1 MAPEG family LAMTOR PF15454.1 EME88052.1 - 1.9e-11 44.0 0.4 1.9e-11 44.0 0.2 1.6 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PAN_1 PF00024.21 EME88053.1 - 0.00064 19.4 1.2 0.0013 18.4 0.8 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EME88053.1 - 0.045 13.4 4.4 0.16 11.6 3.1 2.0 1 1 0 1 1 1 0 PAN domain DUF3703 PF12487.3 EME88054.1 - 0.75 9.4 3.2 0.31 10.7 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) HET PF06985.6 EME88055.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Bacillus_HBL PF05791.6 EME88056.1 - 0.0011 18.3 0.1 0.0014 18.0 0.1 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF4618 PF15397.1 EME88056.1 - 0.0045 16.3 1.5 0.0053 16.1 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF4407 PF14362.1 EME88056.1 - 0.0083 15.1 2.4 0.01 14.7 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PRP1_N PF06424.7 EME88056.1 - 0.0096 16.2 2.3 0.012 15.9 1.6 1.2 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TTKRSYEDQ PF10212.4 EME88056.1 - 0.02 13.8 1.3 0.023 13.6 0.9 1.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TMCO5 PF14992.1 EME88056.1 - 0.021 13.9 1.3 0.025 13.7 0.9 1.1 1 0 0 1 1 1 0 TMCO5 family DUF2681 PF10883.3 EME88056.1 - 0.024 14.8 2.8 0.058 13.6 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) GAS PF13851.1 EME88056.1 - 0.034 13.3 2.9 0.042 13.0 2.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 EME88056.1 - 0.057 13.7 0.9 0.057 13.7 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) CCDC-167 PF15188.1 EME88056.1 - 0.088 12.7 0.2 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 EME88056.1 - 0.11 12.0 1.1 0.13 11.7 0.8 1.1 1 0 0 1 1 1 0 IncA protein BRE1 PF08647.6 EME88056.1 - 0.14 12.1 2.1 0.21 11.5 1.4 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HSP70 PF00012.15 EME88058.1 - 7.4e-266 882.8 11.7 8.4e-266 882.6 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EME88058.1 - 7.4e-20 70.8 0.6 6e-19 67.7 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EME88058.1 - 0.006 15.4 0.2 0.11 11.3 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EME88058.1 - 0.3 10.1 5.7 0.24 10.4 0.1 2.8 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EME88058.1 - 7.8 6.3 9.4 4.6 7.1 0.2 4.1 4 1 0 4 4 4 0 Cell division protein FtsA adh_short PF00106.20 EME88059.1 - 2.8e-32 111.9 2.6 3.7e-32 111.5 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME88059.1 - 1.1e-26 94.0 0.1 1.4e-26 93.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME88059.1 - 2.2e-14 53.5 0.6 3.4e-14 52.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME88059.1 - 3.9e-06 26.4 0.1 5.5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PsbY PF06298.6 EME88059.1 - 0.16 11.5 2.1 1.6 8.3 0.6 2.5 1 1 1 2 2 2 0 Photosystem II protein Y (PsbY) Asp PF00026.18 EME88060.1 - 1.1e-49 169.4 1.4 1.2e-49 169.2 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EME88060.1 - 2.8e-05 24.5 0.9 0.2 12.2 0.0 3.6 3 0 0 3 3 3 1 Aspartyl protease TAXi_N PF14543.1 EME88060.1 - 0.00023 21.1 0.0 0.0012 18.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EME88060.1 - 0.0014 18.1 0.1 0.014 14.9 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EME88060.1 - 0.016 15.0 0.3 0.045 13.5 0.2 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Cupin_5 PF06172.6 EME88061.1 - 1.2e-24 86.7 0.0 1.4e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 Cupin superfamily (DUF985) DUF2240 PF09999.4 EME88061.1 - 0.12 11.8 0.0 22 4.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2240) SET PF00856.23 EME88062.1 - 8e-10 39.2 0.0 5.5e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 SET domain Sugar_tr PF00083.19 EME88063.1 - 2.2e-27 95.7 29.1 7.2e-17 61.0 6.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME88063.1 - 5.6e-17 61.4 57.5 3.8e-15 55.4 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEMT PF04191.8 EME88063.1 - 0.073 13.1 3.9 0.24 11.5 0.3 2.9 2 0 0 2 2 2 0 Phospholipid methyltransferase Tweety PF04906.8 EME88063.1 - 0.25 9.7 0.1 0.4 9.0 0.1 1.2 1 0 0 1 1 1 0 Tweety CtaG_Cox11 PF04442.9 EME88064.1 - 5e-56 188.7 0.0 6.2e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cupin_2 PF07883.6 EME88065.1 - 2.2e-05 23.8 0.0 3.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain SUR7 PF06687.7 EME88066.1 - 3.1e-38 131.4 5.0 3.5e-38 131.3 3.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EME88066.1 - 1.7e-07 31.1 2.8 3.5e-06 26.8 0.3 2.2 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction YjgP_YjgQ PF03739.9 EME88066.1 - 0.044 12.5 0.0 0.065 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF805 PF05656.9 EME88066.1 - 0.24 11.2 6.1 0.14 11.9 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Fig1 PF12351.3 EME88066.1 - 0.57 10.0 9.1 0.11 12.3 3.5 1.8 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Bromodomain PF00439.20 EME88067.1 - 1.4e-18 66.5 0.0 2.6e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Bromodomain DUF2236 PF09995.4 EME88069.1 - 1.7e-37 129.0 0.0 2.5e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) RasGEF PF00617.14 EME88070.1 - 3.7e-46 157.2 0.1 1.3e-45 155.4 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EME88070.1 - 8.3e-15 54.7 0.0 3e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Miro PF08477.8 EME88070.1 - 0.00011 22.7 0.0 0.00024 21.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EME88070.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Ras family zf-HIT PF04438.11 EME88071.1 - 2.8e-09 36.4 13.9 5.1e-09 35.6 9.7 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EME88071.1 - 0.0039 17.0 13.8 0.0077 16.0 9.6 1.5 1 0 0 1 1 1 1 MYND finger Tnp_P_element PF12017.3 EME88071.1 - 0.095 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Transposase protein MSA-2c PF12238.3 EME88071.1 - 2.5 7.7 0.0 2.5 7.7 0.0 2.2 1 1 1 2 2 2 0 Merozoite surface antigen 2c zf-B_box PF00643.19 EME88071.1 - 4.2 7.3 11.6 9.6 6.1 8.0 1.6 1 0 0 1 1 1 0 B-box zinc finger Shisa PF13908.1 EME88071.1 - 9.2 6.4 13.8 26 4.9 9.3 1.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator WD40 PF00400.27 EME88072.1 - 4e-07 29.6 5.1 0.06 13.2 0.1 4.7 5 1 0 5 5 5 3 WD domain, G-beta repeat LisH PF08513.6 EME88072.1 - 0.015 15.0 0.1 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 LisH Pyridox_oxidase PF01243.15 EME88073.1 - 5.8e-06 26.2 0.0 2.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EME88073.1 - 0.022 14.8 0.0 0.42 10.7 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2635 PF10948.3 EME88073.1 - 0.1 11.9 0.4 11 5.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2635) MFS_1 PF07690.11 EME88074.1 - 0.07 11.8 0.1 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily APC_CDC26 PF10471.4 EME88074.1 - 9.7 7.0 12.3 16 6.3 8.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Glyco_hydro_32N PF00251.15 EME88075.1 - 2.7e-29 102.5 0.0 4.2e-26 92.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 EME88075.1 - 9.3e-06 24.9 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EME88075.1 - 1.6e-05 23.8 0.1 2.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Levansucrase/Invertase Sugar_tr PF00083.19 EME88076.1 - 2.4e-91 306.6 25.3 2.7e-91 306.4 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88076.1 - 3e-23 82.1 27.1 3e-23 82.1 18.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 EME88076.1 - 2.9e-05 22.9 8.9 2.9e-05 22.9 6.2 2.0 2 0 0 2 2 2 1 PUCC protein TRI12 PF06609.8 EME88076.1 - 0.00019 19.7 2.9 0.00019 19.7 2.0 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EME88076.1 - 0.00099 17.9 4.1 0.0022 16.7 2.8 1.6 1 1 0 1 1 1 1 BT1 family DUF1228 PF06779.9 EME88076.1 - 0.019 14.9 0.3 0.019 14.9 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Fungal_trans PF04082.13 EME88077.1 - 7.4e-16 57.7 0.0 1.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88077.1 - 9.7e-09 34.9 12.1 1.7e-08 34.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FHA PF00498.21 EME88078.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 FHA domain Tim17 PF02466.14 EME88079.1 - 1.8e-23 82.9 1.7 1.8e-23 82.9 1.2 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF1793 PF08760.6 EME88080.1 - 1.2e-54 184.7 0.0 4.4e-54 182.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EME88080.1 - 0.029 13.5 0.2 0.087 11.9 0.0 1.8 2 0 0 2 2 2 0 beta-Glucocerebrosidase 2 N terminal zf-C2H2_4 PF13894.1 EME88081.1 - 0.043 14.1 4.1 0.15 12.4 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME88081.1 - 0.052 13.7 0.2 0.052 13.7 0.1 2.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME88081.1 - 0.35 11.1 6.5 7.2 6.9 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EME88082.1 - 0.034 13.8 2.7 0.073 12.7 1.9 1.6 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger TspO_MBR PF03073.10 EME88083.1 - 1.2e-41 141.6 6.2 1.5e-41 141.3 4.3 1.1 1 0 0 1 1 1 1 TspO/MBR family MitoNEET_N PF10660.4 EME88083.1 - 1.9 8.4 5.4 2.1 8.2 0.2 2.8 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF4187 PF13821.1 EME88084.1 - 4.7e-24 83.7 0.4 1.2e-23 82.4 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EME88084.1 - 1e-23 83.4 0.9 4.2e-23 81.4 0.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EME88084.1 - 3.4e-13 50.2 1.5 8.2e-13 49.0 0.7 2.0 1 1 0 1 1 1 1 Arsenite-resistance protein 2 CBF PF03914.12 EME88085.1 - 2e-42 144.4 0.1 6e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.9 EME88086.1 - 1.1e-50 171.2 2.5 1.3e-50 171.0 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DIOX_N PF14226.1 EME88088.1 - 2.8e-21 76.2 0.0 4.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME88088.1 - 2.7e-20 72.5 0.0 6.6e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2188 PF09954.4 EME88088.1 - 0.11 12.3 1.3 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) PH PF00169.24 EME88089.1 - 0.00066 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF3106 PF11304.3 EME88089.1 - 0.13 12.7 1.5 0.22 11.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Aminotran_1_2 PF00155.16 EME88090.1 - 4.2e-44 150.9 0.0 6e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Kelch_6 PF13964.1 EME88090.1 - 0.0019 18.3 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Kelch motif KH_1 PF00013.24 EME88092.1 - 1.4e-92 303.2 25.7 4.4e-14 51.8 0.2 12.2 14 0 0 14 14 14 8 KH domain KH_3 PF13014.1 EME88092.1 - 8.9e-67 219.8 20.6 2.2e-09 36.7 1.0 11.5 11 0 0 11 11 11 9 KH domain KH_2 PF07650.12 EME88092.1 - 1.5e-14 53.2 22.0 0.046 13.2 0.2 8.0 8 0 0 8 8 8 5 KH domain SLS PF14611.1 EME88092.1 - 1.1e-11 44.5 1.4 0.00037 19.9 0.0 6.6 6 2 2 8 8 8 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EME88092.1 - 2.7e-06 26.9 4.1 2.7 7.6 0.0 5.4 5 0 0 5 5 5 3 KH domain Elong-fact-P_C PF09285.6 EME88092.1 - 0.054 12.8 0.0 5.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Elongation factor P, C-terminal KH_5 PF13184.1 EME88092.1 - 0.27 11.0 9.2 7.4 6.4 0.0 5.6 6 1 0 6 6 6 0 NusA-like KH domain Cyt-b5 PF00173.23 EME88093.1 - 7.3e-23 80.1 0.1 9.8e-23 79.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 EME88094.1 - 8e-71 238.2 0.0 1.4e-70 237.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME88094.1 - 1.1e-44 152.5 0.0 1.8e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EME88094.1 - 6.6e-21 74.4 0.2 2.9e-20 72.4 0.1 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EME88094.1 - 2.4e-06 26.7 0.0 3.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME88094.1 - 0.014 15.1 0.1 0.33 10.6 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family HET PF06985.6 EME88095.1 - 0.11 12.6 0.3 0.27 11.3 0.1 1.7 1 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) VHS PF00790.14 EME88096.1 - 1.3e-34 118.8 0.0 2.8e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EME88096.1 - 2.9e-08 33.1 0.1 5.9e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EME88096.1 - 1.7e-07 30.6 0.0 3.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EME88096.1 - 3.4e-07 29.5 0.1 7.4e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain UIM PF02809.15 EME88096.1 - 0.0053 16.2 1.3 0.0053 16.2 0.9 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif GAT PF03127.9 EME88096.1 - 0.044 13.7 0.1 1.1 9.3 0.0 2.8 3 1 0 3 3 3 0 GAT domain Rap1_C PF11626.3 EME88097.1 - 5.1e-22 77.5 0.0 4.5e-21 74.5 0.0 2.7 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EME88097.1 - 1.6e-18 66.2 1.2 4.2e-17 61.7 0.2 2.5 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EME88097.1 - 8.5e-08 32.7 0.9 1.3e-05 25.7 0.1 3.1 2 0 0 2 2 2 1 Rap1, DNA-binding zf-DHHC PF01529.15 EME88098.1 - 8.8e-33 113.1 0.3 8.8e-33 113.1 0.2 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase MAT1 PF06391.8 EME88099.1 - 1.3e-34 119.5 13.7 1.3e-34 119.5 9.5 1.4 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EME88099.1 - 0.00051 19.7 8.4 0.0047 16.6 1.1 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME88099.1 - 0.00081 19.0 7.1 0.0017 17.9 4.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME88099.1 - 0.0021 17.6 6.8 0.012 15.2 4.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME88099.1 - 0.0041 17.1 7.3 0.012 15.6 5.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME88099.1 - 0.042 13.4 5.6 0.35 10.5 1.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EME88099.1 - 0.042 13.6 10.3 0.069 12.9 6.3 2.0 1 1 1 2 2 2 0 Ring finger domain Tim17 PF02466.14 EME88100.1 - 9.3e-34 116.2 6.1 1.2e-33 115.9 4.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EME88100.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal NUC153 PF08159.7 EME88101.1 - 5.3e-12 45.1 4.4 1.4e-11 43.7 3.1 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EME88101.1 - 0.015 15.1 0.0 7.7 6.5 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Med13_C PF06333.7 EME88102.1 - 2.2e-64 217.5 0.0 1.9e-63 214.5 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal DUF2196 PF09962.4 EME88103.1 - 7.4e-22 76.9 4.1 1.1e-21 76.3 2.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) MPLKIP PF15502.1 EME88103.1 - 2.5 8.7 14.3 0.87 10.2 2.6 2.2 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein PAT1 PF09770.4 EME88104.1 - 1.7 6.7 17.8 2.1 6.4 12.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 EME88105.1 - 2.5e-66 219.4 4.7 2e-23 81.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M28 PF04389.12 EME88106.1 - 2.9e-32 111.8 0.0 4.9e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EME88106.1 - 3.5e-07 29.9 0.0 6.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans PF04082.13 EME88108.1 - 1.3e-28 99.5 0.0 2.5e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88108.1 - 0.0043 16.9 4.0 0.011 15.6 2.8 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.17 EME88109.1 - 2.4e-86 290.4 0.1 3.8e-86 289.8 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Ribosomal_L13 PF00572.13 EME88110.1 - 2.8e-27 95.2 0.0 4.7e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 BAG PF02179.11 EME88111.1 - 1.6e-18 66.5 0.5 2.7e-18 65.8 0.3 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EME88111.1 - 0.00013 21.2 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EME88111.1 - 0.02 15.0 0.1 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain AMP-binding PF00501.23 EME88112.1 - 1.1e-64 218.4 0.1 1.3e-64 218.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME88112.1 - 1e-16 61.6 0.0 2.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3535 PF12054.3 EME88113.1 - 1.9e-133 445.3 0.5 1.3e-132 442.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EME88113.1 - 9.9e-71 237.9 0.0 2.2e-70 236.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME88113.1 - 4.7e-14 51.9 0.0 1.9e-13 50.0 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EME88113.1 - 3.6e-13 48.3 17.6 0.007 16.3 0.0 10.5 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EME88113.1 - 1.8e-06 28.2 0.0 0.034 14.5 0.0 4.1 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EME88113.1 - 9.1e-05 21.9 0.0 0.36 10.1 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal HEAT_2 PF13646.1 EME88113.1 - 0.00015 22.0 22.5 0.0055 16.9 0.1 8.3 7 2 1 8 8 7 1 HEAT repeats Cnd1 PF12717.2 EME88113.1 - 0.014 15.2 0.3 10 5.9 0.0 4.6 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 EME88113.1 - 0.016 15.1 0.4 11 6.0 0.0 3.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EME88113.1 - 0.031 14.7 31.4 0.29 11.6 0.0 10.3 10 1 2 12 12 12 0 HEAT-like repeat DUF1546 PF07571.8 EME88113.1 - 0.087 12.9 0.3 56 3.9 0.0 4.7 5 0 0 5 5 4 0 Protein of unknown function (DUF1546) Isochorismatase PF00857.15 EME88115.1 - 1.6e-18 67.2 0.0 2.4e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family MAGE PF01454.14 EME88116.1 - 4.9e-40 136.9 0.0 6e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 MAGE family GPP34 PF05719.6 EME88116.1 - 0.048 13.7 0.0 0.25 11.3 0.0 2.1 2 1 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Med31 PF05669.7 EME88117.1 - 1.9e-34 117.4 0.2 2.3e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 SOH1 MethyTransf_Reg PF10119.4 EME88117.1 - 1.1 9.7 3.9 43 4.6 2.7 3.0 1 1 0 1 1 1 0 Predicted methyltransferase regulatory domain SF3b10 PF07189.6 EME88118.1 - 4.4e-36 122.5 0.0 4.9e-36 122.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Raptor_N PF14538.1 EME88118.1 - 0.13 12.1 0.0 0.16 11.7 0.0 1.2 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Pal1 PF08316.6 EME88119.1 - 4.5e-44 150.3 1.4 4.5e-44 150.3 1.0 3.0 3 1 0 3 3 3 1 Pal1 cell morphology protein TFIIS_C PF01096.13 EME88120.1 - 2.7e-18 65.2 6.5 2.7e-18 65.2 4.5 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EME88120.1 - 0.0009 18.8 1.9 0.033 13.8 0.1 3.1 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EME88120.1 - 0.011 15.4 9.3 0.17 11.7 1.3 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EME88120.1 - 0.11 12.3 4.6 0.14 11.9 0.0 2.9 3 1 0 3 3 3 0 PhnA Zinc-Ribbon C1_4 PF07975.7 EME88120.1 - 1.1 9.3 7.6 3.7 7.6 0.6 2.7 2 2 0 2 2 2 0 TFIIH C1-like domain zinc-ribbons_6 PF07191.7 EME88120.1 - 8.4 6.2 10.0 2.7 7.8 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbons Ank_2 PF12796.2 EME88121.1 - 6.7e-18 64.8 0.1 6.5e-09 36.0 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME88121.1 - 4.8e-10 38.7 0.0 0.0017 18.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EME88121.1 - 6.2e-10 39.0 0.0 2.2e-05 24.5 0.0 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME88121.1 - 3.8e-09 35.9 0.0 0.0067 16.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EME88121.1 - 4.8e-09 36.4 0.0 5.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Arrestin_N PF00339.24 EME88122.1 - 0.0059 16.4 0.0 0.027 14.2 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain bZIP_1 PF00170.16 EME88123.1 - 3.1e-05 23.8 9.4 5.6e-05 23.0 6.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME88123.1 - 0.03 14.1 9.5 0.068 13.0 6.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper rRNA_processing PF08524.6 EME88123.1 - 0.052 13.3 5.0 0.1 12.4 3.5 1.4 1 0 0 1 1 1 0 rRNA processing DUF4407 PF14362.1 EME88123.1 - 1.6 7.6 5.9 2.8 6.8 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EME88124.1 - 8.9e-13 48.7 3.9 8.9e-13 48.7 2.7 4.2 3 1 0 3 3 3 1 Stm1 DOMON PF03351.12 EME88125.1 - 0.00039 20.3 0.2 0.00068 19.5 0.1 1.4 1 0 0 1 1 1 1 DOMON domain PKD PF00801.15 EME88125.1 - 0.057 13.1 1.4 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 PKD domain DUF2427 PF10348.4 EME88125.1 - 0.63 9.6 10.1 0.099 12.2 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 EME88125.1 - 0.67 9.7 11.3 1.1 9.0 7.8 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF1469 PF07332.6 EME88125.1 - 1 9.0 9.9 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) EB1 PF03271.12 EME88126.1 - 1.9e-17 62.9 0.6 3.4e-17 62.2 0.4 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EME88126.1 - 1.5e-05 25.0 0.2 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Phi-29_GP3 PF05435.6 EME88126.1 - 0.033 13.3 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 Syja_N PF02383.13 EME88126.1 - 0.037 12.7 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain NTF2 PF02136.15 EME88127.1 - 2.3e-26 92.4 1.4 4.2e-26 91.6 1.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EME88127.1 - 4.7e-08 32.5 0.3 9.3e-08 31.5 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME88127.1 - 1.9e-05 24.5 0.1 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME88127.1 - 3.3e-05 23.6 0.1 6.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EME88127.1 - 0.0035 17.1 0.1 0.0035 17.1 0.1 1.9 2 0 0 2 2 2 1 RNA binding motif Glyco_transf_90 PF05686.7 EME88128.1 - 9.7e-30 103.5 1.2 1.3e-29 103.1 0.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EME88128.1 - 1e-08 35.3 0.3 2.8e-08 33.9 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Septin PF00735.13 EME88129.1 - 4.8e-11 42.1 0.0 4e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EME88129.1 - 8.3e-06 25.7 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EME88129.1 - 0.0021 18.5 0.0 0.0052 17.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EME88129.1 - 0.0038 17.0 0.1 3.6 7.3 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.1 EME88129.1 - 0.013 15.5 2.2 0.56 10.1 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain MobB PF03205.9 EME88129.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EME88129.1 - 0.026 13.7 0.1 6.1 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EME88129.1 - 0.028 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1810 PF08837.6 EME88130.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) PT PF04886.7 EME88130.1 - 3.2 7.1 7.4 0.7 9.2 2.5 1.9 2 0 0 2 2 2 0 PT repeat EthD PF07110.6 EME88131.1 - 0.0012 19.7 0.2 0.0043 17.9 0.1 1.7 1 1 0 1 1 1 1 EthD domain CS PF04969.11 EME88134.1 - 1.9e-16 60.3 0.1 4.1e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 CS domain Fungal_trans PF04082.13 EME88135.1 - 2.8e-08 32.9 0.1 2.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C3HC PF07967.8 EME88136.1 - 6.6e-39 132.7 2.2 4.1e-30 104.2 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EME88136.1 - 1.8e-17 62.9 1.2 9.3e-17 60.6 0.1 2.5 2 1 0 2 2 2 1 Rsm1-like DUF1604 PF07713.8 EME88136.1 - 0.076 12.8 0.1 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Cep57_MT_bd PF06657.8 EME88137.1 - 1.2e-21 76.4 0.2 1.2e-21 76.4 0.2 4.8 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EME88137.1 - 2.9e-05 23.8 5.2 2.9e-05 23.8 3.6 5.1 4 2 1 5 5 5 2 Centrosome localisation domain of PPC89 Cep57_CLD PF14073.1 EME88137.1 - 0.00014 21.7 9.8 0.00014 21.7 6.8 3.8 3 1 1 4 4 4 1 Centrosome localisation domain of Cep57 DUF1202 PF06717.6 EME88137.1 - 0.0048 16.2 0.5 0.0048 16.2 0.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1202) WD40_alt PF14077.1 EME88137.1 - 0.25 11.0 6.6 3.5 7.3 0.7 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif Sugar_tr PF00083.19 EME88138.1 - 3.3e-81 273.1 22.5 3.8e-81 272.9 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88138.1 - 2.8e-13 49.3 32.4 3.4e-10 39.1 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME88138.1 - 4.8e-06 25.2 29.1 0.00016 20.1 0.8 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein DUF4149 PF13664.1 EME88139.1 - 1.4e-24 86.0 2.5 1.6e-24 85.8 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 EME88140.1 - 3.6e-32 111.3 0.0 6.8e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EME88140.1 - 2.7e-18 66.2 0.2 4.8e-18 65.4 0.2 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EME88140.1 - 1.3e-13 50.8 0.1 5.3e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like VWA_2 PF13519.1 EME88140.1 - 0.00077 19.6 1.0 0.0019 18.3 0.7 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_30 PF13604.1 EME88140.1 - 0.032 13.7 0.2 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain VWA PF00092.23 EME88140.1 - 0.036 13.7 0.3 0.2 11.3 0.1 2.1 1 1 1 2 2 2 0 von Willebrand factor type A domain Birna_VP3 PF01767.11 EME88141.1 - 0.26 10.8 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP3 protein UAA PF08449.6 EME88142.1 - 5.4e-12 45.2 7.2 9.1e-12 44.5 5.0 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EME88142.1 - 7.9e-11 41.5 1.1 1.4e-10 40.6 0.7 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EME88142.1 - 4.6e-07 29.9 20.0 0.00014 21.9 1.7 3.3 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EME88142.1 - 0.0002 21.0 16.4 0.045 13.3 5.4 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family AGTRAP PF06396.6 EME88142.1 - 1.5 8.4 6.0 0.19 11.4 0.3 2.2 2 1 1 3 3 3 0 Angiotensin II, type I receptor-associated protein (AGTRAP) GFO_IDH_MocA PF01408.17 EME88144.1 - 1.4e-08 35.2 0.8 4.1e-08 33.7 0.5 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_transf_8 PF01501.15 EME88145.1 - 2.9e-33 115.2 0.0 4.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EME88145.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative TPP_enzyme_N PF02776.13 EME88148.1 - 3.4e-46 156.8 0.0 8.4e-46 155.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME88148.1 - 3.8e-24 85.0 0.6 9.3e-24 83.7 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME88148.1 - 2e-20 72.9 0.0 3.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ETF PF01012.16 EME88148.1 - 0.038 13.7 0.1 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Electron transfer flavoprotein domain 2OG-FeII_Oxy_2 PF13532.1 EME88149.1 - 1.7e-34 119.3 0.0 3.1e-34 118.5 0.0 1.4 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EME88149.1 - 0.047 14.2 0.0 0.66 10.5 0.0 2.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily AAA PF00004.24 EME88151.1 - 8.4e-16 58.3 0.0 1.5e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME88151.1 - 0.00013 22.0 0.2 0.094 12.8 0.0 2.9 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.17 EME88151.1 - 0.0042 17.2 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 1 RNA helicase Zot PF05707.7 EME88151.1 - 0.01 15.2 0.1 0.048 13.1 0.0 2.0 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) NACHT PF05729.7 EME88151.1 - 0.02 14.5 0.1 0.09 12.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EME88151.1 - 0.04 13.9 3.7 0.067 13.1 0.3 3.0 2 2 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EME88151.1 - 0.062 13.0 0.3 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EME88151.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EME88151.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EME88151.1 - 0.074 13.3 0.1 0.9 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 EME88151.1 - 0.13 11.3 0.8 0.49 9.4 0.2 1.9 1 1 1 2 2 2 0 KaiC Ribosomal_L6 PF00347.18 EME88152.1 - 4.1e-24 84.8 0.1 1.1e-12 48.2 0.0 3.1 4 0 0 4 4 4 2 Ribosomal protein L6 APG17 PF04108.7 EME88153.1 - 9.3e-05 21.3 3.8 0.064 12.0 0.0 2.8 1 1 1 3 3 3 2 Autophagy protein Apg17 Baculo_PEP_C PF04513.7 EME88153.1 - 0.00064 19.5 2.0 0.47 10.2 0.0 2.8 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 EME88153.1 - 0.019 15.0 3.8 7.4 6.7 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 EME88153.1 - 0.028 14.4 2.1 0.031 14.3 0.3 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EME88153.1 - 0.037 13.6 3.2 2.7 7.5 1.5 2.4 1 1 1 2 2 2 0 IncA protein AATF-Che1 PF13339.1 EME88153.1 - 0.046 13.8 1.2 0.31 11.1 0.3 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Snapin_Pallidin PF14712.1 EME88153.1 - 0.082 13.2 0.9 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 Snapin/Pallidin DUF948 PF06103.6 EME88153.1 - 0.09 12.6 1.3 9.9 6.1 0.0 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 EME88153.1 - 0.099 12.4 4.7 4.1 7.2 0.2 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EME88153.1 - 0.11 11.7 1.9 3.5 6.7 0.3 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EME88153.1 - 0.21 11.4 4.1 1.4 8.7 2.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tht1 PF04163.7 EME88153.1 - 0.25 9.7 5.0 0.37 9.1 3.5 1.3 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein DUF848 PF05852.6 EME88153.1 - 0.29 10.9 2.6 12 5.7 0.9 2.9 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Laminin_II PF06009.7 EME88153.1 - 0.59 9.8 3.9 2.5 7.8 0.1 2.7 2 2 0 2 2 2 0 Laminin Domain II AIP3 PF03915.8 EME88153.1 - 1.5 7.6 7.1 1.2 7.9 0.9 2.3 2 1 0 3 3 3 0 Actin interacting protein 3 WD40 PF00400.27 EME88155.1 - 1.8e-41 138.5 4.9 1.6e-10 40.4 0.1 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.2 EME88155.1 - 2.5e-12 46.3 0.1 6.4e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME88155.1 - 1.3e-09 37.4 0.2 3.8e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EME88155.1 - 1.9e-07 29.6 0.2 0.0004 18.6 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EME88155.1 - 2e-07 30.7 1.1 6.6e-05 22.4 0.2 3.2 3 1 0 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 EME88155.1 - 0.033 12.9 0.1 14 4.2 0.0 3.2 3 1 0 3 3 3 0 Nup133 N terminal like MraZ PF02381.13 EME88155.1 - 0.1 12.3 0.5 15 5.3 0.0 3.1 3 0 0 3 3 3 0 MraZ protein PQQ_3 PF13570.1 EME88155.1 - 0.37 11.1 8.4 24 5.3 0.0 6.2 7 3 0 7 7 7 0 PQQ-like domain FAD_binding_4 PF01565.18 EME88156.1 - 1.1e-19 70.2 1.2 2.7e-19 69.0 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME88156.1 - 7.6e-06 25.7 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like SPX PF03105.14 EME88157.1 - 8e-52 176.7 5.6 1.3e-51 176.0 3.9 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EME88157.1 - 5.2e-31 108.0 38.7 7.2e-31 107.5 26.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EME88157.1 - 9.1e-13 47.5 43.5 1.9e-11 43.1 16.6 2.4 1 1 1 2 2 2 2 Citrate transporter Sugar_tr PF00083.19 EME88158.1 - 2.5e-77 260.3 25.5 2.9e-77 260.1 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88158.1 - 5.3e-17 61.5 24.5 5.3e-17 61.5 17.0 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF3123 PF11321.3 EME88158.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) zf-CSL PF05207.8 EME88159.1 - 6.1e-25 86.4 1.6 7.3e-25 86.2 1.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EME88159.1 - 0.022 14.6 0.3 0.039 13.8 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EME88159.1 - 0.12 11.9 0.4 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Frataxin_Cyay PF01491.11 EME88160.1 - 1.8e-34 117.7 0.0 2.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain BiPBP_C PF06832.7 EME88160.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family DUF747 PF05346.6 EME88161.1 - 1.6e-130 435.0 2.2 2e-130 434.7 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PsbU PF06514.6 EME88163.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) HIT PF01230.18 EME88165.1 - 4.5e-18 65.5 0.0 8.5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EME88165.1 - 0.00017 21.8 0.4 0.0013 18.9 0.1 2.3 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Diphthamide_syn PF01866.12 EME88166.1 - 4.7e-53 180.4 0.0 1.9e-52 178.4 0.0 1.8 2 0 0 2 2 2 1 Putative diphthamide synthesis protein DUF3609 PF12259.3 EME88167.1 - 0.061 11.9 0.1 0.12 11.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3609) DUF1682 PF07946.9 EME88167.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HemY_N PF07219.8 EME88167.1 - 1.7 8.1 4.9 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Lig_chan PF00060.21 EME88167.1 - 9 5.9 8.1 51 3.5 5.6 2.0 1 1 0 1 1 1 0 Ligand-gated ion channel Ribosomal_L2_C PF03947.13 EME88170.1 - 1.1e-44 151.3 2.7 2.4e-44 150.2 1.9 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EME88170.1 - 1.4e-25 89.0 0.9 3.4e-25 87.7 0.6 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EME88171.1 - 4.7e-45 152.2 0.1 3e-44 149.6 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME88171.1 - 1.8e-33 114.9 0.0 3.4e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Senescence_reg PF04520.8 EME88171.1 - 0.19 12.2 4.3 0.39 11.2 3.0 1.6 1 0 0 1 1 1 0 Senescence regulator Dicty_REP PF05086.7 EME88171.1 - 1.1 6.8 7.1 1.7 6.3 4.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.13 EME88172.1 - 2.8e-08 33.5 9.9 4.3e-08 32.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME88173.1 - 5.2e-23 81.2 0.1 1.1e-22 80.1 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88173.1 - 2.6e-09 36.8 8.4 5.4e-09 35.8 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EME88177.1 - 4.2 7.9 7.8 0.95 9.9 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger p450 PF00067.17 EME88179.1 - 3.7e-96 322.4 0.0 4.3e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 EME88180.1 - 2.9e-45 153.7 0.0 2.8e-43 147.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME88180.1 - 0.00011 22.9 0.0 0.0011 19.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME88180.1 - 0.00018 20.9 0.1 0.00096 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EME88180.1 - 0.00019 20.5 0.0 0.00055 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EME88180.1 - 0.00044 20.4 0.0 0.0075 16.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EME88180.1 - 0.0005 19.0 0.0 0.00084 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 EME88180.1 - 0.0006 19.8 0.1 0.024 14.6 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EME88180.1 - 0.0013 18.1 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EME88180.1 - 0.0027 17.6 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EME88180.1 - 0.0042 16.8 0.1 0.021 14.5 0.0 2.3 2 0 0 2 2 1 1 Part of AAA domain RNA_helicase PF00910.17 EME88180.1 - 0.0043 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EME88180.1 - 0.005 15.6 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EME88180.1 - 0.018 14.7 0.0 0.063 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EME88180.1 - 0.021 14.0 0.1 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EME88180.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EME88180.1 - 0.037 13.2 0.0 0.084 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 EME88180.1 - 0.037 14.3 0.0 0.09 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EME88180.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME88180.1 - 0.082 12.7 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME88180.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EME88180.1 - 0.11 12.1 0.1 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EME88180.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EME88180.1 - 0.22 10.0 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Abhydro_lipase PF04083.11 EME88181.1 - 3.2e-18 64.8 0.0 7.9e-18 63.5 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EME88181.1 - 4.7e-07 29.9 0.1 1.2e-06 28.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME88181.1 - 0.0013 18.3 0.0 0.0031 17.1 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold hNIFK_binding PF12196.3 EME88181.1 - 2 7.8 4.1 1.4 8.3 0.6 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Acyltransferase PF01553.16 EME88185.1 - 5.1e-14 51.8 0.0 7.9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ins_allergen_rp PF06757.8 EME88185.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification bZIP_1 PF00170.16 EME88186.1 - 0.0045 16.8 13.7 0.019 14.8 9.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor DUF2046 PF09755.4 EME88186.1 - 0.013 14.3 2.2 0.02 13.8 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) PAP1 PF08601.5 EME88186.1 - 0.027 14.1 0.7 0.13 11.9 0.3 1.9 1 1 0 1 1 1 0 Transcription factor PAP1 bZIP_2 PF07716.10 EME88186.1 - 1.4 8.8 12.4 6.2 6.7 8.6 2.0 1 1 0 1 1 1 0 Basic region leucine zipper DUF904 PF06005.7 EME88186.1 - 4.5 7.6 8.7 0.28 11.5 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Cys_Met_Meta_PP PF01053.15 EME88189.1 - 7.8e-140 465.5 0.0 8.9e-140 465.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EME88189.1 - 5.4e-08 32.1 0.1 9.8e-08 31.3 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EME88189.1 - 3.5e-06 26.0 0.6 5.2e-06 25.4 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EME88189.1 - 3.9e-06 26.2 0.0 9.2e-06 25.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EME88189.1 - 2.7e-05 23.3 0.4 6.2e-05 22.2 0.3 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF604 PF04646.7 EME88190.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EME88190.1 - 1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Glyco_transf_90 PF05686.7 EME88191.1 - 1.2e-20 73.6 3.1 1.4e-20 73.3 2.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EME88191.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ank_5 PF13857.1 EME88192.1 - 1.2e-14 54.0 0.1 3.1e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME88192.1 - 3.7e-12 46.4 0.5 7.2e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME88192.1 - 1.4e-10 41.3 0.0 2e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EME88192.1 - 6.8e-06 25.6 0.6 0.0043 16.8 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EME88192.1 - 0.00072 19.5 0.1 0.012 15.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeat GCV_T PF01571.16 EME88192.1 - 0.082 12.2 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain MFS_1 PF07690.11 EME88194.1 - 1.2e-19 70.2 28.0 1.2e-19 70.2 19.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME88194.1 - 0.007 14.9 22.7 0.22 10.0 15.7 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TAFII55_N PF04658.8 EME88195.1 - 8.5e-46 155.4 0.2 8.5e-46 155.4 0.2 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region Init_tRNA_PT PF04179.7 EME88195.1 - 0.16 10.7 1.4 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Initiator tRNA phosphoribosyl transferase HNF-1_N PF04814.8 EME88195.1 - 2.4 8.1 10.8 1.3 9.1 5.0 2.4 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ank_4 PF13637.1 EME88196.1 - 1.2e-36 124.4 1.7 3.1e-09 37.1 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME88196.1 - 2.6e-36 123.8 0.0 3.5e-20 72.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME88196.1 - 5.1e-33 111.2 0.7 8.9e-08 31.5 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EME88196.1 - 1.9e-29 98.7 0.3 1.6e-07 30.8 0.0 5.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EME88196.1 - 3.4e-28 97.0 4.4 1.8e-09 37.5 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DUF3447 PF11929.3 EME88196.1 - 0.033 13.9 0.0 0.27 11.0 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 EME88196.1 - 0.09 12.2 0.0 10 5.5 0.0 2.7 2 1 1 3 3 3 0 Shigella flexneri OspC protein GSDH PF07995.6 EME88197.1 - 0.00021 20.4 0.1 0.00073 18.7 0.1 2.0 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EME88197.1 - 0.051 13.5 0.0 37 4.5 0.0 3.8 3 0 0 3 3 3 0 NHL repeat AdoHcyase PF05221.12 EME88198.1 - 3e-130 432.9 0.0 2e-129 430.2 0.0 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EME88198.1 - 6.7e-86 286.1 1.9 1e-85 285.5 1.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EME88198.1 - 7.7e-08 31.6 0.1 1.7e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EME88198.1 - 0.00035 19.9 0.2 0.00056 19.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EME88198.1 - 0.0015 18.4 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EME88198.1 - 0.0059 16.2 0.2 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 EME88198.1 - 0.037 14.4 0.2 0.08 13.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.14 EME88198.1 - 0.047 12.3 1.1 0.14 10.8 0.2 1.9 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase adh_short PF00106.20 EME88198.1 - 0.067 13.1 1.0 9.8 6.0 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF4448 PF14610.1 EME88198.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) YchF-GTPase_C PF06071.8 EME88200.1 - 2.2e-33 113.8 0.3 4.8e-33 112.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EME88200.1 - 3.8e-11 42.9 0.0 9.3e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME88200.1 - 0.0078 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EME88200.1 - 0.012 15.4 0.1 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 TGS domain Dynamin_N PF00350.18 EME88200.1 - 0.1 12.4 0.0 3.1 7.6 0.0 2.7 2 1 0 3 3 3 0 Dynamin family DUF3721 PF12518.3 EME88200.1 - 0.16 11.5 0.6 0.29 10.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function AAA_23 PF13476.1 EME88200.1 - 2.9 8.1 6.2 44 4.3 4.3 2.5 1 1 0 1 1 1 0 AAA domain Ank_5 PF13857.1 EME88201.1 - 5.8e-17 61.3 3.2 5e-10 39.3 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) VPS9 PF02204.13 EME88201.1 - 4.4e-15 55.5 0.0 9.3e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EME88201.1 - 1.9e-11 44.1 0.4 0.0008 19.7 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME88201.1 - 1.5e-10 41.3 1.2 0.0023 18.3 0.0 5.3 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME88201.1 - 9.7e-07 28.4 0.3 1.8 9.0 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 EME88201.1 - 3.8e-06 26.4 1.5 0.041 13.7 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.19 EME88201.1 - 0.0025 17.6 0.0 0.0079 15.9 0.0 1.9 1 0 0 1 1 1 1 PX domain PAP2 PF01569.16 EME88202.1 - 8.3e-23 80.4 0.9 8.3e-23 80.4 0.6 1.8 2 1 0 2 2 2 1 PAP2 superfamily Aminotran_3 PF00202.16 EME88203.1 - 3.7e-95 318.6 0.0 4.7e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EME88203.1 - 0.00034 19.6 0.0 0.0014 17.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II NHase_beta PF02211.10 EME88203.1 - 0.031 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit MFS_1 PF07690.11 EME88204.1 - 4.6e-35 120.9 31.1 9.4e-35 119.9 21.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Steroid_dh PF02544.11 EME88205.1 - 1.8e-31 108.9 0.1 2.6e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EME88205.1 - 4e-05 23.0 0.3 6.1e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EME88205.1 - 0.0044 17.1 0.8 0.0089 16.1 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase An_peroxidase PF03098.10 EME88206.1 - 1.5e-92 310.7 0.0 3.1e-90 303.0 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EME88206.1 - 1.8e-06 26.7 0.0 1.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 DUF2470 PF10615.4 EME88207.1 - 1.2e-15 57.4 0.1 1.9e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyridoxal_deC PF00282.14 EME88207.1 - 0.068 11.5 0.0 0.092 11.1 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Daxx PF03344.10 EME88208.1 - 7.8 4.8 17.8 8.9 4.6 12.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF1843 PF08898.5 EME88209.1 - 0.11 12.5 1.0 0.34 10.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF3827 PF12877.2 EME88209.1 - 0.4 8.7 5.4 0.48 8.4 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SOBP PF15279.1 EME88209.1 - 0.93 9.8 3.7 1 9.6 2.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GAS2 PF02187.12 EME88210.1 - 7.5e-05 22.4 0.1 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF1192 PF06698.6 EME88210.1 - 0.099 12.4 1.4 0.64 9.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DEC-1_N PF04625.8 EME88212.1 - 0.0041 15.8 6.1 0.0049 15.6 4.2 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.14 EME88212.1 - 0.025 14.9 0.2 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PLRV_ORF5 PF01690.12 EME88212.1 - 0.17 10.9 4.7 0.21 10.7 3.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1180 PF06679.7 EME88212.1 - 0.22 11.4 1.2 0.28 11.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAP_N PF01213.14 EME88212.1 - 0.96 8.6 5.5 1.3 8.2 3.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal APH PF01636.18 EME88214.1 - 3.5e-11 43.3 0.3 4.9e-10 39.5 0.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EME88214.1 - 0.00024 20.3 0.0 0.00057 19.1 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EME88214.1 - 0.0011 17.6 0.0 0.002 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EME88214.1 - 0.0019 17.8 0.0 0.004 16.7 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EME88214.1 - 0.0052 15.9 0.0 0.38 9.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain tRNA-synt_His PF13393.1 EME88214.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase SNF2_N PF00176.18 EME88215.1 - 2.9e-34 118.2 0.0 9.8e-34 116.5 0.0 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain Ribosomal_L3 PF00297.17 EME88217.1 - 3.2e-118 393.8 7.5 3.9e-118 393.6 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NAGLU PF05089.7 EME88218.1 - 3.3e-129 430.4 8.4 4.5e-129 429.9 5.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EME88218.1 - 1.7e-59 201.3 7.8 2.3e-59 200.9 5.4 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EME88218.1 - 7e-17 60.8 0.0 1.6e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Abhydrolase_3 PF07859.8 EME88219.1 - 1.7e-32 112.7 0.1 7.3e-24 84.5 0.0 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME88219.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family HMG_box PF00505.14 EME88220.1 - 3.1e-22 78.5 0.5 6.6e-22 77.5 0.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EME88220.1 - 3.5e-06 27.2 0.2 8e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain Glu-tRNAGln PF02686.10 EME88222.1 - 9e-06 25.4 0.1 9.8e-05 22.0 0.1 2.2 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.1 EME88223.1 - 8e-115 382.8 16.6 9e-115 382.6 11.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EME88223.1 - 1.2e-08 34.8 14.0 0.00046 20.0 3.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME88223.1 - 4e-05 23.1 13.8 0.41 10.5 0.1 5.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME88223.1 - 0.00028 20.4 19.1 0.035 13.7 2.6 3.8 1 1 3 4 4 4 4 TPR repeat Spatacsin_C PF14649.1 EME88223.1 - 0.002 17.0 9.2 0.67 8.7 6.2 3.0 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_2 PF07719.12 EME88223.1 - 0.0052 16.6 16.8 0.86 9.6 0.1 5.9 5 2 1 6 6 6 2 Tetratricopeptide repeat AAA_10 PF12846.2 EME88223.1 - 0.02 14.3 2.3 0.083 12.3 0.6 2.0 2 0 0 2 2 2 0 AAA-like domain Foie-gras_1 PF11817.3 EME88223.1 - 0.044 13.2 7.6 0.16 11.4 5.2 1.9 1 1 0 1 1 1 0 Foie gras liver health family 1 DUF3564 PF12087.3 EME88223.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) TPR_6 PF13174.1 EME88223.1 - 0.29 11.6 17.5 19 5.9 0.3 6.2 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME88223.1 - 3.3 8.5 13.0 7.7 7.4 0.2 5.2 2 1 5 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME88223.1 - 6.2 6.8 15.1 1.8 8.4 0.9 5.0 3 1 3 6 6 6 0 Tetratricopeptide repeat Mus7 PF09462.5 EME88224.1 - 1.1e-132 444.0 15.2 1.6e-132 443.4 10.5 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family Tetraspannin PF00335.15 EME88225.1 - 0.0053 16.0 4.4 0.012 14.9 2.3 2.0 1 1 0 1 1 1 1 Tetraspanin family Endostatin PF06482.6 EME88225.1 - 0.039 13.3 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PrgI PF12666.2 EME88225.1 - 0.19 11.8 2.7 0.74 10.0 0.4 2.3 2 0 0 2 2 2 0 PrgI family protein MMR_HSR1 PF01926.18 EME88226.1 - 5.6e-06 26.2 0.0 7.6e-05 22.6 0.0 2.7 2 1 0 3 3 3 1 50S ribosome-binding GTPase Glyco_transf_34 PF05637.7 EME88227.1 - 3e-65 220.0 0.0 3.6e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Hpt PF01627.18 EME88228.1 - 5.4e-12 45.5 0.1 1.4e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Hpt domain Aminotran_1_2 PF00155.16 EME88229.1 - 4.2e-90 302.3 0.0 4.9e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BING4CT PF08149.6 EME88230.1 - 5.9e-40 134.6 0.0 6e-37 125.0 0.0 2.7 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 EME88230.1 - 5.5e-06 26.0 0.0 0.0061 16.3 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EME88230.1 - 3.2e-05 22.9 0.1 0.0088 14.8 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region DUF4173 PF13777.1 EME88231.1 - 0.46 9.7 11.0 0.12 11.6 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4173) Epiglycanin_C PF14654.1 EME88231.1 - 7.2 6.6 6.9 19 5.3 0.5 2.5 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region WD40 PF00400.27 EME88232.1 - 9.9e-24 82.3 1.0 7.3e-06 25.6 0.0 8.2 9 0 0 9 9 9 5 WD domain, G-beta repeat AMP-binding PF00501.23 EME88233.1 - 7.9e-92 307.7 0.3 9.6e-92 307.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME88233.1 - 1.6e-21 77.0 0.1 2.7e-18 66.6 0.1 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 EME88234.1 - 1.2e-57 194.9 11.1 1.2e-57 194.9 7.7 2.8 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EME88234.1 - 2.4e-45 154.6 3.9 6e-45 153.3 2.7 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EME88234.1 - 2.2e-42 145.0 6.3 2.2e-42 145.0 4.4 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EME88234.1 - 6.8e-19 67.8 34.4 6.8e-19 67.8 23.8 4.7 3 2 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 EME88234.1 - 6.1e-15 55.8 2.0 4.7e-14 52.9 1.4 2.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 EME88234.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide AAA PF00004.24 EME88235.1 - 1.7e-39 135.0 0.0 8.4e-39 132.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME88235.1 - 0.00019 21.5 0.1 0.0035 17.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EME88235.1 - 0.0002 21.2 0.0 0.0082 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME88235.1 - 0.0002 21.3 1.9 0.009 16.0 0.0 3.8 2 2 2 4 4 4 1 AAA ATPase domain RuvB_N PF05496.7 EME88235.1 - 0.00024 20.2 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EME88235.1 - 0.00029 21.6 0.1 0.0011 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EME88235.1 - 0.001 17.8 0.1 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EME88235.1 - 0.0023 17.6 1.4 0.0093 15.7 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EME88235.1 - 0.0031 17.2 0.1 0.0084 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EME88235.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EME88235.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME88235.1 - 0.013 14.8 0.1 0.028 13.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EME88235.1 - 0.016 14.3 0.1 0.044 12.9 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI IPT PF01745.11 EME88235.1 - 0.039 13.1 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase AAA_18 PF13238.1 EME88235.1 - 0.04 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME88235.1 - 0.04 14.0 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EME88235.1 - 0.043 13.2 0.2 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 EME88235.1 - 0.12 11.9 0.5 0.21 11.1 0.3 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EME88235.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EME88235.1 - 0.19 11.4 0.0 5.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase PhoH PF02562.11 EME88235.1 - 0.27 10.4 0.0 0.71 9.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein NfeD PF01957.13 EME88236.1 - 0.12 12.4 3.7 0.85 9.7 0.0 2.7 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding MARVEL PF01284.18 EME88236.1 - 1.1 9.1 18.1 14 5.4 12.7 2.2 1 1 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.7 EME88236.1 - 1.3 8.5 7.8 7.3 6.0 5.4 2.0 1 1 0 1 1 1 0 SUR7/PalI family ADH_N PF08240.7 EME88237.1 - 5.7e-23 80.7 5.1 1e-22 79.9 3.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME88237.1 - 9.7e-15 54.2 0.0 9.7e-14 51.0 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EME88237.1 - 0.0016 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EME88237.1 - 0.0082 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EME88237.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_2 PF07992.9 EME88237.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 EME88237.1 - 0.095 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.22 EME88237.1 - 0.14 12.6 0.2 9.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EME88237.1 - 1.5 8.6 4.4 2.7 7.8 1.1 2.2 1 1 1 2 2 2 0 ThiF family ADH_zinc_N PF00107.21 EME88238.1 - 4.9e-26 90.8 0.0 1.1e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME88238.1 - 6.8e-21 74.0 1.5 1e-20 73.4 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME88238.1 - 5.3e-05 24.1 0.0 0.0001 23.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EME88238.1 - 0.00012 21.6 0.2 0.00039 19.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 EME88238.1 - 0.0058 16.6 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 EME88238.1 - 0.019 15.3 0.1 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EME88238.1 - 0.074 12.9 0.4 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 EME88238.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EME88238.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 EME88239.1 - 3.4e-22 78.3 2.1 4.9e-22 77.8 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME88239.1 - 5.3e-14 51.8 0.8 6.3e-12 45.2 0.6 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME88239.1 - 0.0033 18.3 0.5 0.007 17.2 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Kri1_C PF12936.2 EME88241.1 - 2.6e-27 94.6 0.1 2.6e-27 94.6 0.1 4.4 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 EME88241.1 - 5.6e-24 84.3 17.4 5.6e-24 84.3 12.0 5.7 4 2 0 4 4 4 1 KRI1-like family DEAD PF00270.24 EME88242.1 - 1e-40 138.9 0.0 5.3e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME88242.1 - 6.1e-27 93.3 0.1 1.5e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EME88242.1 - 9.3e-06 24.6 0.0 1.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EME88242.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M28 PF04389.12 EME88244.1 - 1.2e-36 126.1 0.0 2.3e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PK PF00224.16 EME88246.1 - 8.5e-171 567.2 4.4 1e-170 566.9 3.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EME88246.1 - 5.5e-31 106.5 0.0 1.4e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EME88246.1 - 0.00016 20.6 0.6 0.00037 19.4 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.11 EME88247.1 - 3.9e-38 131.0 43.3 3.9e-38 131.0 30.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PGA2 PF07543.7 EME88247.1 - 0.015 15.0 0.4 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 SPC25 PF06703.6 EME88248.1 - 1.1e-49 168.0 0.2 1.3e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EME88249.1 - 1.8e-58 196.7 0.3 2.4e-58 196.3 0.2 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 CK_II_beta PF01214.13 EME88250.1 - 3.6e-73 245.0 0.8 4.3e-73 244.7 0.5 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RIC1 PF07064.8 EME88251.1 - 2.6e-76 256.5 0.0 3.7e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EME88251.1 - 0.041 13.7 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 EME88252.1 - 1.7e-10 40.0 0.3 1e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain BESS PF02944.15 EME88252.1 - 0.096 12.2 0.4 0.95 9.0 0.1 2.4 2 0 0 2 2 2 0 BESS motif DUF666 PF05006.7 EME88253.1 - 0.056 13.4 1.0 0.056 13.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF666) Fer2_3 PF13085.1 EME88253.1 - 0.2 11.4 1.1 0.23 11.3 0.7 1.1 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain HGTP_anticodon PF03129.15 EME88254.1 - 1.3e-12 47.4 0.0 2.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EME88254.1 - 0.035 13.7 0.1 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) CBF PF03914.12 EME88255.1 - 4.1e-48 162.9 0.3 1.1e-47 161.5 0.1 1.9 2 0 0 2 2 2 1 CBF/Mak21 family DNA_alkylation PF08713.6 EME88255.1 - 0.08 12.4 1.5 2.4 7.6 0.1 2.9 3 0 0 3 3 3 0 DNA alkylation repair enzyme PUA PF01472.15 EME88256.1 - 9.2e-13 47.7 0.0 3.4e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 PUA domain TPR_11 PF13414.1 EME88257.1 - 1.2e-18 66.4 7.9 2.8e-15 55.7 2.0 3.1 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EME88257.1 - 2.6e-13 48.9 7.0 4e-05 23.0 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME88257.1 - 1.1e-11 43.7 6.5 0.00012 21.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EME88257.1 - 1.7e-07 30.8 0.7 0.0033 17.4 0.2 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME88257.1 - 2.8e-05 23.5 2.9 0.083 12.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME88257.1 - 3.1e-05 23.8 3.8 0.16 11.8 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME88257.1 - 7.2e-05 22.2 0.2 0.25 11.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EME88257.1 - 9.2e-05 22.7 2.1 0.9 10.3 0.2 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EME88257.1 - 0.0054 17.0 1.5 0.1 12.9 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME88257.1 - 0.01 16.4 12.6 0.024 15.3 0.1 3.4 4 1 1 5 5 3 0 Tetratricopeptide repeat MIT PF04212.13 EME88257.1 - 0.022 14.6 0.9 0.64 9.9 0.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 EME88257.1 - 0.024 14.5 1.0 1.6 8.6 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.6 EME88257.1 - 0.063 12.7 9.9 0.039 13.4 4.1 2.2 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.1 EME88257.1 - 0.18 12.3 2.3 2.1 8.9 0.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.2 EME88258.1 - 0.0031 17.1 0.2 0.0072 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-U1 PF06220.7 EME88259.1 - 2.5e-05 23.7 0.5 2.5e-05 23.7 0.3 1.6 2 0 0 2 2 2 1 U1 zinc finger CCDC84 PF14968.1 EME88259.1 - 0.021 14.3 3.3 0.034 13.6 2.2 1.3 1 1 0 1 1 1 0 Coiled coil protein 84 DUF2076 PF09849.4 EME88259.1 - 0.023 14.7 6.1 0.25 11.3 2.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TetR_C_6 PF13977.1 EME88259.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial transcriptional repressor PaaA_PaaC PF05138.7 EME88259.1 - 0.096 11.6 0.4 0.13 11.2 0.3 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein FNIP_N PF14636.1 EME88259.1 - 5.6 7.4 6.7 0.63 10.5 0.8 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus 4HBT PF03061.17 EME88260.1 - 2.8e-10 40.1 0.0 4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME88260.1 - 0.00094 18.9 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Macoilin PF09726.4 EME88261.1 - 9.9 4.3 12.8 14 3.8 8.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Tocopherol_cycl PF14249.1 EME88262.1 - 0.014 14.1 0.2 0.026 13.2 0.1 1.7 2 1 0 2 2 2 0 Tocopherol cyclase ALG3 PF05208.8 EME88262.1 - 0.15 11.2 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 ALG3 protein Fapy_DNA_glyco PF01149.19 EME88264.1 - 5e-23 81.6 0.0 1.1e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EME88264.1 - 7.4e-23 80.1 0.0 1.9e-22 78.8 0.0 1.7 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Arginase PF00491.16 EME88265.1 - 1.6e-90 303.1 0.0 1.9e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EME88265.1 - 0.059 13.5 1.7 0.18 12.0 1.2 1.8 1 1 0 1 1 1 0 UPF0489 domain Rcd1 PF04078.8 EME88266.1 - 9.5e-131 434.3 2.4 1.1e-130 434.1 1.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DUF106 PF01956.11 EME88267.1 - 4.8 6.6 8.0 10 5.6 2.8 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 TraG_N PF07916.6 EME88268.1 - 0.12 10.8 3.2 0.16 10.3 2.2 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TcpE PF12648.2 EME88268.1 - 0.19 11.8 0.7 0.35 11.0 0.5 1.3 1 0 0 1 1 1 0 TcpE family UPF0233 PF06781.7 EME88268.1 - 0.22 11.1 1.1 0.38 10.3 0.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Tannase PF07519.6 EME88269.1 - 2.7e-97 326.4 6.3 3.2e-97 326.2 4.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EME88269.1 - 0.00097 19.0 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME88269.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cid2 PF09774.4 EME88270.1 - 2.3e-46 157.6 0.0 3.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF1330 PF07045.6 EME88270.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) DNA_ligase_A_M PF01068.16 EME88272.1 - 1.3e-55 187.9 0.6 2.8e-44 150.9 0.2 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EME88272.1 - 5.4e-51 172.9 0.0 9.2e-51 172.1 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EME88272.1 - 5.6e-29 100.4 0.0 2.4e-28 98.3 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EME88272.1 - 0.063 12.9 0.1 15 5.3 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain SURF4 PF02077.10 EME88273.1 - 6.5e-96 320.7 7.8 7.4e-96 320.6 5.4 1.0 1 0 0 1 1 1 1 SURF4 family DUF3325 PF11804.3 EME88273.1 - 2.9 7.8 13.2 0.1 12.5 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) DUF2104 PF09877.4 EME88273.1 - 4.8 7.2 12.6 4.9 7.1 1.4 3.6 3 2 0 3 3 3 0 Predicted membrane protein (DUF2104) Nup84_Nup100 PF04121.8 EME88274.1 - 2.1e-68 230.6 11.9 1.3e-65 221.4 8.3 3.0 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 HNH_5 PF14279.1 EME88274.1 - 0.066 13.2 0.0 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease DUF3336 PF11815.3 EME88275.1 - 8.6e-23 80.4 0.3 4e-22 78.2 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EME88275.1 - 1.6e-12 47.8 0.0 4.2e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3322 PF11795.3 EME88275.1 - 0.00062 19.4 0.4 0.0065 16.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF2630 PF10944.3 EME88275.1 - 0.0034 17.4 0.4 0.01 15.8 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) Glyco_transf_34 PF05637.7 EME88277.1 - 1.3e-65 221.2 2.0 5.2e-65 219.2 1.4 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glutaredoxin PF00462.19 EME88279.1 - 1.3e-21 76.3 0.1 1.9e-19 69.3 0.0 2.6 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EME88279.1 - 3e-16 59.0 0.0 9.8e-16 57.3 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EME88279.1 - 0.00031 20.7 0.0 0.0092 16.0 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME88279.1 - 0.021 15.0 0.2 0.28 11.3 0.0 2.6 2 2 0 2 2 2 0 Thioredoxin-like domain GST_N_3 PF13417.1 EME88279.1 - 0.089 13.0 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 EME88279.1 - 0.14 12.2 0.0 0.55 10.3 0.0 1.9 3 0 0 3 3 3 0 ArsC family Brix PF04427.13 EME88280.1 - 1.4e-35 122.7 0.2 2e-35 122.1 0.2 1.2 1 0 0 1 1 1 1 Brix domain Zn_Tnp_IS91 PF14319.1 EME88281.1 - 0.85 9.1 7.4 1.1 8.8 0.1 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain NDUFB10 PF10249.4 EME88282.1 - 0.00019 21.6 0.1 0.00022 21.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EME88282.1 - 0.068 13.6 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase PCI PF01399.22 EME88283.1 - 7.9e-14 51.8 0.0 2.4e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EME88283.1 - 0.00022 20.6 1.5 0.00023 20.5 0.3 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EME88283.1 - 0.00097 19.4 0.4 1.5 9.1 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat Translin PF01997.11 EME88283.1 - 0.041 13.4 0.5 0.15 11.6 0.2 2.0 2 0 0 2 2 2 0 Translin family Methyltransf_16 PF10294.4 EME88285.1 - 6.4e-13 48.5 0.0 8.2e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EME88285.1 - 0.00044 19.9 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EME88285.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_18 PF12847.2 EME88285.1 - 0.0027 18.2 0.0 0.0045 17.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EME88285.1 - 0.027 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EME88285.1 - 0.046 13.3 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain UcrQ PF02939.11 EME88286.1 - 3.5e-28 97.2 0.0 4.2e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EME88287.1 - 7.8e-25 87.8 4.8 7.8e-25 87.8 3.3 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 EME88287.1 - 0.0041 16.0 3.2 0.0063 15.4 2.2 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.13 EME88287.1 - 0.063 13.0 1.5 0.12 12.1 1.0 1.5 1 1 0 1 1 1 0 GatB domain MgtE_N PF03448.12 EME88287.1 - 0.11 12.7 2.5 8.8 6.7 0.1 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain SUN PF03856.8 EME88289.1 - 1.3e-90 303.0 25.6 1.8e-90 302.6 17.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Actin PF00022.14 EME88290.1 - 1.4e-117 392.4 0.0 1.7e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EME88290.1 - 0.097 11.2 0.0 0.44 9.0 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein AhpC-TSA_2 PF13911.1 EME88291.1 - 4.4e-18 65.2 0.0 5.8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EME88291.1 - 4.4e-07 29.6 0.0 6.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME88291.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Gin PF10764.4 EME88291.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DUF1713 PF08213.6 EME88292.1 - 1.5e-12 46.8 21.3 1.5e-12 46.8 14.8 2.2 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EME88292.1 - 0.0071 16.2 1.6 0.016 15.1 0.0 2.3 3 0 0 3 3 3 1 Mitochondrial protein Pet20 Glyoxalase_2 PF12681.2 EME88293.1 - 1.1e-08 35.6 0.6 0.00038 21.0 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EME88293.1 - 4.1e-08 33.2 2.7 2.3e-06 27.6 0.8 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PIG-F PF06699.6 EME88294.1 - 4e-50 170.4 13.6 1.1e-49 169.0 9.5 1.6 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.4 EME88294.1 - 0.069 13.2 1.7 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.4 EME88294.1 - 0.11 12.7 1.5 8.2 6.7 0.3 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EME88294.1 - 0.28 10.8 6.0 2.2 8.0 4.2 2.1 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EME88294.1 - 0.37 10.3 4.7 5.9 6.4 3.3 2.2 1 1 0 1 1 1 0 YMGG-like Gly-zipper zf-Tim10_DDP PF02953.10 EME88297.1 - 6e-22 76.7 5.0 7.5e-22 76.3 3.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EME88297.1 - 0.015 14.7 4.5 0.024 14.0 3.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) CDC37_N PF03234.9 EME88297.1 - 0.18 12.1 0.5 0.22 11.8 0.3 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Vicilin_N PF04702.7 EME88297.1 - 0.25 10.9 2.6 0.31 10.6 1.8 1.1 1 0 0 1 1 1 0 Vicilin N terminal region Translin PF01997.11 EME88298.1 - 5.7e-48 163.1 0.0 6.6e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EME88298.1 - 0.044 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 GMP synthase C terminal domain adh_short PF00106.20 EME88300.1 - 5.6e-22 78.4 1.2 1.2e-21 77.3 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME88300.1 - 1.5e-10 41.2 0.0 2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME88300.1 - 4.4e-10 39.5 0.1 5.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EME88300.1 - 0.016 14.1 0.1 0.023 13.6 0.1 1.4 1 1 0 1 1 1 0 Male sterility protein Saccharop_dh PF03435.13 EME88300.1 - 0.032 13.2 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EME88300.1 - 0.033 14.2 1.7 0.29 11.1 1.2 2.1 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EME88300.1 - 0.052 12.9 0.0 0.082 12.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family COPIIcoated_ERV PF07970.7 EME88301.1 - 6.1e-33 114.3 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EME88301.1 - 2.6e-23 81.8 0.0 4.7e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Homeobox PF00046.24 EME88302.1 - 1.1e-06 28.1 0.5 1.5e-06 27.7 0.4 1.2 1 0 0 1 1 1 1 Homeobox domain NmrA PF05368.8 EME88303.1 - 1.3e-09 37.6 0.0 2.4e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EME88303.1 - 0.061 13.2 0.4 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EME88303.1 - 0.064 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF4201 PF13870.1 EME88304.1 - 0.039 13.3 6.0 0.081 12.3 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) KTI12 PF08433.5 EME88304.1 - 0.06 12.5 1.1 0.11 11.6 0.8 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 G-gamma PF00631.17 EME88304.1 - 0.19 11.4 1.4 0.46 10.2 0.0 2.4 2 1 1 3 3 3 0 GGL domain Fib_alpha PF08702.5 EME88304.1 - 0.96 9.5 4.6 3.4 7.7 0.2 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PDEase_I PF00233.14 EME88305.1 - 1.7e-51 175.2 0.0 9.5e-46 156.4 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF3336 PF11815.3 EME88306.1 - 5.7e-45 152.3 7.7 8.6e-45 151.8 5.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EME88306.1 - 4.3e-19 69.2 0.2 2e-18 67.0 0.1 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Peptidase_M22 PF00814.20 EME88307.1 - 2.5e-48 164.9 0.0 8.2e-48 163.2 0.0 1.8 1 1 0 1 1 1 1 Glycoprotease family PilM_2 PF11104.3 EME88307.1 - 0.0018 17.2 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; YycC PF14174.1 EME88307.1 - 0.03 13.9 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 YycC-like protein DUF1932 PF09130.6 EME88308.1 - 4.7e-19 67.9 0.0 8.2e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EME88308.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME88308.1 - 1.7e-07 31.5 0.0 3.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EME88308.1 - 0.0003 19.9 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.12 EME88308.1 - 0.014 14.2 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Transketolase_N PF00456.16 EME88310.1 - 5.5e-148 492.2 0.1 7.3e-148 491.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EME88310.1 - 1.3e-45 155.0 0.0 2.2e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME88310.1 - 1.4e-13 50.8 0.0 2.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EME88310.1 - 0.00016 20.6 0.0 0.0014 17.6 0.0 2.1 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EME88310.1 - 0.00067 18.4 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Tropomyosin_1 PF12718.2 EME88311.1 - 0.0065 16.3 20.1 0.0065 16.3 13.9 5.2 3 1 3 6 6 6 2 Tropomyosin like ATG16 PF08614.6 EME88311.1 - 0.043 13.6 53.8 0.36 10.6 15.2 4.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 EME88311.1 - 0.5 9.6 55.1 2.5 7.3 15.8 3.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 EME88311.1 - 1 9.1 14.6 1.1 9.0 0.3 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.14 EME88311.1 - 2.5 5.7 61.1 1.3 6.6 13.5 3.3 2 1 1 3 3 3 0 Myosin tail Reo_sigmaC PF04582.7 EME88311.1 - 2.7 7.0 21.2 1.3 8.1 7.7 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein COG2 PF06148.6 EME88311.1 - 3 7.7 24.5 0.056 13.3 1.6 4.0 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EME88311.1 - 3.8 7.0 55.4 0.093 12.3 6.0 4.1 2 1 3 5 5 5 0 IncA protein Vac_Fusion PF02346.11 EME88311.1 - 7.2 6.1 9.3 18 4.8 0.8 3.3 3 1 1 4 4 4 0 Chordopoxvirus fusion protein AAA_13 PF13166.1 EME88311.1 - 7.9 4.8 45.8 0.005 15.3 12.1 2.8 1 1 0 2 2 2 0 AAA domain Amidohydro_4 PF13147.1 EME88312.1 - 7.4e-13 49.1 0.4 5.5e-06 26.6 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EME88312.1 - 5.2e-07 29.6 0.3 2.9e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EME88312.1 - 1.8e-05 24.1 0.0 3.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EME88312.1 - 0.0005 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 Amidohydrolase Vps39_1 PF10366.4 EME88313.1 - 4.4e-29 100.6 0.0 2.7e-28 98.1 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EME88313.1 - 1.6e-27 95.8 0.0 6.3e-27 93.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EME88313.1 - 2.5e-18 66.4 0.0 1.2e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 CNH domain TPR_12 PF13424.1 EME88313.1 - 1.7e-05 24.6 2.1 0.075 12.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.15 EME88313.1 - 0.00098 18.7 2.8 0.00098 18.7 1.9 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 EME88313.1 - 0.0025 17.3 4.9 1.6 8.4 0.8 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME88313.1 - 0.011 15.3 1.1 14 5.3 0.1 4.3 2 2 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EME88313.1 - 0.013 16.1 0.0 7.9 7.2 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EME88313.1 - 0.029 14.2 3.1 11 6.2 0.8 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME88313.1 - 0.034 14.4 6.5 5.7 7.3 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME88313.1 - 1.4 8.8 5.8 2.5 8.0 0.7 3.6 4 1 0 4 4 3 0 Tetratricopeptide repeat LSM PF01423.17 EME88314.1 - 2e-13 49.6 0.3 3.2e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF2205 PF10224.4 EME88315.1 - 0.063 12.8 0.6 0.099 12.2 0.1 1.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Ebp2 PF05890.7 EME88315.1 - 0.11 11.7 3.7 0.12 11.6 2.6 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 Atrophin-1 PF03154.10 EME88315.1 - 2.2 6.2 7.2 2.4 6.2 5.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family CFEM PF05730.6 EME88316.1 - 2.6e-13 49.5 8.4 7.3e-13 48.1 5.8 1.8 1 0 0 1 1 1 1 CFEM domain Rifin_STEVOR PF02009.11 EME88316.1 - 6.1 6.3 17.2 17 4.8 11.9 1.8 1 1 0 1 1 1 0 Rifin/stevor family ATP-synt_B PF00430.13 EME88316.1 - 6.2 6.6 9.6 13 5.5 6.7 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Zds_C PF08632.5 EME88318.1 - 6e-31 105.6 1.1 1.4e-30 104.4 0.8 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Serglycin PF04360.7 EME88318.1 - 0.0031 17.2 7.3 0.0096 15.6 5.1 1.9 1 0 0 1 1 1 1 Serglycin Mpv17_PMP22 PF04117.7 EME88319.1 - 2.2e-20 72.0 0.2 4.6e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF3341 PF11821.3 EME88319.1 - 0.18 11.2 4.4 0.053 13.0 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) COX15-CtaA PF02628.10 EME88320.1 - 5.6e-95 317.6 11.7 6.8e-95 317.3 8.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BTB PF00651.26 EME88321.1 - 3.1e-06 27.1 0.0 6.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Med7 PF05983.6 EME88323.1 - 2.8e-48 163.7 2.2 3.2e-48 163.5 1.5 1.0 1 0 0 1 1 1 1 MED7 protein DUF3469 PF11952.3 EME88323.1 - 0.11 12.1 0.2 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) PAP2 PF01569.16 EME88324.1 - 1.5e-22 79.6 0.6 1.5e-22 79.6 0.4 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF3325 PF11804.3 EME88324.1 - 0.004 17.0 0.8 0.004 17.0 0.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) 7tm_7 PF08395.7 EME88324.1 - 0.009 15.0 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 7tm Chemosensory receptor RseC_MucC PF04246.7 EME88324.1 - 7.8 6.0 7.1 27 4.3 1.1 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC MFS_1 PF07690.11 EME88325.1 - 8.8e-40 136.4 47.9 8.8e-40 136.4 33.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME88325.1 - 6.5e-11 41.4 15.0 6.5e-11 41.4 10.4 3.1 2 1 2 4 4 4 1 Sugar (and other) transporter DUF4191 PF13829.1 EME88325.1 - 0.076 12.1 0.0 0.076 12.1 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4191) UPF0370 PF13980.1 EME88325.1 - 0.084 12.6 0.4 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) PWWP PF00855.12 EME88329.1 - 0.0098 16.0 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 1 PWWP domain DUF1325 PF07039.6 EME88329.1 - 0.019 14.5 0.5 0.036 13.6 0.3 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain TUDOR PF00567.19 EME88329.1 - 0.038 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Tudor domain CNP1 PF08750.6 EME88329.1 - 0.038 13.6 0.3 0.091 12.4 0.2 1.6 1 0 0 1 1 1 0 CNP1-like family DUF4537 PF15057.1 EME88329.1 - 0.066 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) PAP1 PF08601.5 EME88330.1 - 1.8e-43 149.6 29.8 1.8e-43 149.6 20.7 2.8 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EME88330.1 - 9.6e-10 38.2 9.0 1.9e-09 37.3 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME88330.1 - 0.049 13.4 13.3 0.16 11.8 8.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 EME88330.1 - 0.19 12.0 10.4 0.44 10.8 7.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EME88330.1 - 0.55 9.8 4.7 1.1 8.8 3.2 1.4 1 0 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 EME88330.1 - 4 7.9 8.3 0.42 11.1 0.8 2.8 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Bap31 PF05529.7 EME88330.1 - 4.7 6.6 5.7 8.5 5.7 3.9 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Cellulase PF00150.13 EME88332.1 - 6.2e-13 48.5 0.3 6.2e-13 48.5 0.2 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CLTH PF10607.4 EME88335.1 - 6.4e-27 94.0 0.0 6.4e-27 94.0 0.0 2.2 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 EME88335.1 - 0.0079 16.1 0.4 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 U-box domain Fes1 PF08609.5 EME88335.1 - 0.009 16.4 1.7 0.024 15.1 1.2 1.6 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 LisH PF08513.6 EME88335.1 - 0.024 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 LisH Translin PF01997.11 EME88335.1 - 0.37 10.3 5.4 0.36 10.3 2.8 1.5 1 1 0 1 1 1 0 Translin family V_ATPase_I PF01496.14 EME88335.1 - 2.1 6.1 4.2 2.7 5.7 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EME88335.1 - 6.6 5.0 6.4 11 4.3 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) A_deaminase PF00962.17 EME88336.1 - 3.4e-34 118.2 0.0 4.3e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Syntaxin PF00804.20 EME88338.1 - 5.2e-11 42.6 10.5 7.2e-11 42.1 2.7 2.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EME88338.1 - 1.7e-10 40.4 5.2 4.4e-10 39.1 3.6 1.8 1 0 0 1 1 1 1 SNARE domain DUF4094 PF13334.1 EME88338.1 - 0.031 14.6 0.2 0.031 14.6 0.1 3.1 3 1 1 4 4 3 0 Domain of unknown function (DUF4094) Synaptobrevin PF00957.16 EME88338.1 - 0.11 12.0 3.7 0.34 10.5 2.6 1.8 1 1 0 1 1 1 0 Synaptobrevin PBP1_TM PF14812.1 EME88338.1 - 0.16 12.3 1.1 0.18 12.1 0.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin_2 PF13098.1 EME88338.1 - 0.23 11.6 1.4 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Pepsin-I3 PF06394.8 EME88338.1 - 0.24 11.0 3.8 0.63 9.7 2.6 1.6 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Allexi_40kDa PF05549.6 EME88338.1 - 0.32 10.2 6.8 0.14 11.4 0.9 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein V-SNARE PF05008.10 EME88338.1 - 0.88 9.7 5.6 29 4.9 0.0 3.2 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Syntaxin_2 PF14523.1 EME88338.1 - 0.96 9.5 9.7 3.6 7.6 3.1 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Mod_r PF07200.8 EME88338.1 - 5.6 6.8 13.4 4.2 7.2 4.0 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein KTI12 PF08433.5 EME88339.1 - 9.4e-84 280.8 0.0 1.1e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EME88339.1 - 4.6e-05 23.3 0.0 7.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EME88339.1 - 0.019 15.7 0.0 0.044 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME88339.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EME88339.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit E1-E2_ATPase PF00122.15 EME88341.1 - 3.7e-59 199.5 2.8 3.7e-59 199.5 2.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EME88341.1 - 6.7e-47 159.3 7.0 6.7e-47 159.3 4.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EME88341.1 - 2.2e-23 83.8 0.0 1.6e-22 81.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME88341.1 - 6.8e-19 67.6 0.0 1.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EME88341.1 - 5.9e-12 46.1 0.1 1.5e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EME88341.1 - 1.3e-05 24.9 0.9 2.6e-05 23.9 0.3 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME88341.1 - 0.00014 21.2 0.2 0.00049 19.5 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF3325 PF11804.3 EME88341.1 - 0.26 11.2 0.0 0.26 11.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) p450 PF00067.17 EME88342.1 - 6.7e-59 199.6 0.0 7.6e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.13 EME88343.1 - 2e-43 148.4 0.0 2.6e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EME88343.1 - 3.5e-26 91.2 0.0 1.3e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 EME88344.1 - 6.6e-183 607.9 0.1 7.6e-183 607.7 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ligase_CoA PF00549.14 EME88345.1 - 8.2e-34 116.4 2.7 2.8e-17 62.7 0.3 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EME88345.1 - 1.5e-12 47.8 0.9 6.6e-12 45.7 0.0 2.5 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.1 EME88345.1 - 3.9e-09 36.2 0.1 1.9e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EME88345.1 - 0.033 13.5 0.0 0.085 12.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain DUF1754 PF08555.5 EME88346.1 - 0.19 12.3 0.0 0.19 12.3 0.0 2.3 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF2856 PF11043.3 EME88346.1 - 0.54 10.3 3.2 0.88 9.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Acyl-CoA_dh_1 PF00441.19 EME88347.1 - 1.8e-30 106.0 1.6 2.5e-30 105.5 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME88347.1 - 1.9e-20 72.0 0.7 3.3e-20 71.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EME88347.1 - 5.2e-13 49.5 0.1 1.9e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME88347.1 - 7.7e-05 22.9 0.6 0.00013 22.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain OPT PF03169.10 EME88348.1 - 3.7e-152 507.9 47.4 4.2e-152 507.7 32.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.22 EME88349.1 - 4.1e-58 193.0 8.8 1.2e-19 69.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EME88350.1 - 1.1e-25 89.9 0.7 1.6e-25 89.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88350.1 - 2.3e-06 27.4 3.3 4.6e-06 26.4 2.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.8 EME88351.1 - 1.6e-87 293.6 5.3 3.5e-86 289.2 3.7 2.0 1 1 0 1 1 1 1 PrpF protein Pro_racemase PF05544.6 EME88351.1 - 0.022 13.5 3.7 3.4 6.4 0.6 3.2 2 2 0 2 2 2 0 Proline racemase Fungal_trans PF04082.13 EME88353.1 - 2e-17 62.9 0.5 2.8e-17 62.4 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EME88354.1 - 1.4e-20 73.2 0.0 2.4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88354.1 - 0.00015 21.5 2.9 0.00029 20.6 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CASP_C PF08172.7 EME88354.1 - 0.019 14.0 0.1 0.043 12.8 0.1 1.5 1 0 0 1 1 1 0 CASP C terminal WD40 PF00400.27 EME88355.1 - 1.6e-12 46.7 1.3 0.87 9.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Fungal_trans PF04082.13 EME88357.1 - 2.6e-31 108.4 0.9 3.8e-31 107.8 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88357.1 - 0.00018 21.3 15.2 0.00032 20.5 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ceramidase PF05875.7 EME88358.1 - 1.6e-101 338.9 7.2 2e-101 338.5 5.0 1.0 1 0 0 1 1 1 1 Ceramidase Herpes_glycop PF01528.11 EME88358.1 - 0.0025 16.6 0.7 0.0025 16.6 0.5 1.6 1 1 1 2 2 2 1 Herpesvirus glycoprotein M DUF788 PF05620.6 EME88358.1 - 0.24 11.2 1.5 0.36 10.6 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Prefoldin_2 PF01920.15 EME88359.1 - 1.7e-18 66.3 7.5 1.9e-18 66.1 5.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Dynein_IC2 PF11540.3 EME88359.1 - 0.0026 17.0 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 Val_tRNA-synt_C PF10458.4 EME88359.1 - 0.032 14.3 1.4 0.032 14.3 1.0 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Occludin_ELL PF07303.8 EME88359.1 - 0.035 14.8 2.1 0.047 14.4 1.4 1.3 1 0 0 1 1 1 0 Occludin homology domain 3H PF02829.9 EME88359.1 - 0.04 13.9 0.7 0.079 12.9 0.2 1.5 1 1 1 2 2 2 0 3H domain EMP24_GP25L PF01105.19 EME88359.1 - 0.04 13.6 2.1 0.08 12.6 0.1 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1640 PF07798.6 EME88359.1 - 0.052 13.5 3.5 0.07 13.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TMCO5 PF14992.1 EME88359.1 - 0.053 12.6 6.2 0.06 12.4 4.3 1.1 1 0 0 1 1 1 0 TMCO5 family HrpB7 PF09486.5 EME88359.1 - 0.094 12.6 5.2 0.28 11.0 0.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) HR1 PF02185.11 EME88359.1 - 0.13 11.9 6.4 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat TelA PF05816.6 EME88359.1 - 0.18 10.4 4.6 0.14 10.8 0.2 1.9 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) Cob_adeno_trans PF01923.13 EME88359.1 - 0.28 10.9 3.4 2.1 8.1 0.2 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase RasGAP_C PF03836.10 EME88359.1 - 0.3 10.7 6.3 0.23 11.1 1.3 2.1 2 0 0 2 2 2 0 RasGAP C-terminus GvpG PF05120.7 EME88359.1 - 0.36 10.6 0.1 0.36 10.6 0.1 2.0 1 1 1 2 2 2 0 Gas vesicle protein G YjcZ PF13990.1 EME88359.1 - 0.57 9.2 3.3 0.17 10.9 0.3 1.5 2 0 0 2 2 2 0 YjcZ-like protein Seryl_tRNA_N PF02403.17 EME88359.1 - 0.6 10.1 5.8 0.17 11.9 1.4 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.1 EME88359.1 - 0.66 9.9 4.8 0.62 10.0 1.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.1 EME88359.1 - 0.79 10.1 4.6 1.7 9.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 EME88359.1 - 0.97 9.7 3.5 0.94 9.7 0.2 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.6 EME88359.1 - 1.3 8.7 7.1 0.94 9.1 1.6 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Microtub_assoc PF07989.6 EME88359.1 - 2.2 8.1 7.0 0.26 11.1 1.8 1.7 2 1 0 2 2 2 0 Microtubule associated THOC7 PF05615.8 EME88359.1 - 2.6 8.2 10.2 1.2 9.3 1.2 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4200 PF13863.1 EME88359.1 - 4.4 7.2 10.0 2.1 8.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 EME88359.1 - 6.1 6.5 7.6 1.1 8.9 0.8 2.1 2 0 0 2 2 2 0 Prefoldin subunit Lipoprotein_20 PF13942.1 EME88359.1 - 6.5 6.2 6.8 30 4.1 4.7 1.8 1 1 0 1 1 1 0 YfhG lipoprotein Abhydrolase_6 PF12697.2 EME88360.1 - 5.7e-27 95.0 0.0 9.8e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME88360.1 - 2.7e-13 50.0 0.0 1.6e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME88360.1 - 2.2e-06 27.4 0.0 5.8e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EME88360.1 - 0.00035 19.1 0.0 0.00047 18.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EME88360.1 - 0.0028 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase EthD PF07110.6 EME88360.1 - 0.028 15.3 0.0 1.5 9.8 0.0 2.8 3 0 0 3 3 3 0 EthD domain F-box PF00646.28 EME88361.1 - 0.001 18.6 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME88361.1 - 0.14 11.9 0.9 0.3 10.8 0.0 2.2 3 0 0 3 3 3 0 F-box-like Mito_carr PF00153.22 EME88362.1 - 4.5e-67 221.8 0.9 1.4e-22 79.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 EME88362.1 - 0.0071 16.1 0.8 3.6 7.7 0.0 3.0 3 0 0 3 3 3 2 Uperin family MS_channel PF00924.13 EME88363.1 - 5.9e-24 84.5 1.8 9.3e-24 83.8 1.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EME88363.1 - 0.00029 20.4 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EME88363.1 - 0.00055 19.0 0.3 0.0014 17.7 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EME88363.1 - 0.0011 19.0 0.1 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EME88363.1 - 0.0015 17.8 0.0 0.0042 16.3 0.0 1.8 1 0 0 1 1 1 1 EF hand Glyco_trans_2_3 PF13632.1 EME88364.1 - 2.5e-47 161.0 1.5 2.5e-47 161.0 1.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EME88364.1 - 1.3e-06 28.1 0.0 7.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME88364.1 - 1.7e-06 28.0 0.0 5.7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EME88364.1 - 0.0002 20.6 0.0 0.00046 19.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Arylsulfotran_2 PF14269.1 EME88365.1 - 0.00027 20.2 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Glyco_hydro_16 PF00722.16 EME88366.1 - 3e-19 69.0 0.9 5.2e-19 68.2 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 AMP-binding PF00501.23 EME88367.1 - 7.7e-61 205.7 0.0 1.1e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME88367.1 - 2.1e-09 38.1 0.0 5.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 EME88368.1 - 1.3e-14 54.6 0.2 2.3e-14 53.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME88368.1 - 9.2e-10 38.4 0.1 1.2e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EME88368.1 - 0.006 16.2 0.6 0.018 14.6 0.3 1.8 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_8 PF06259.7 EME88368.1 - 0.0074 15.7 0.2 0.45 10.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase DUF900 PF05990.7 EME88368.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) MTTB PF06253.6 EME88368.1 - 0.068 10.9 0.0 0.096 10.4 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) DUF676 PF05057.9 EME88368.1 - 0.1 11.8 0.8 0.19 11.0 0.5 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) BTB PF00651.26 EME88369.1 - 2.4e-26 91.8 0.0 1.6e-13 50.5 0.0 2.9 2 1 1 3 3 3 2 BTB/POZ domain Ank PF00023.25 EME88369.1 - 7.8e-10 38.0 0.7 9.1e-07 28.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EME88369.1 - 8.1e-10 38.9 0.1 2.4e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EME88369.1 - 1.6e-09 37.9 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EME88369.1 - 8.8e-08 32.1 0.1 2.7e-07 30.6 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME88369.1 - 3e-05 23.8 0.2 0.038 14.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat YqzH PF14164.1 EME88369.1 - 0.043 13.7 0.1 5.5 6.9 0.1 2.8 2 0 0 2 2 2 0 YqzH-like protein Pkinase PF00069.20 EME88370.1 - 1.1e-59 201.7 0.0 1.6e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME88370.1 - 6.2e-39 133.6 0.0 1.2e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EME88370.1 - 3.2e-06 26.3 0.1 1.9e-05 23.7 0.0 2.3 2 1 2 4 4 4 1 Kinase-like Phage_GP20 PF06810.6 EME88370.1 - 0.00031 20.2 6.0 0.0017 17.7 4.1 2.0 2 0 0 2 2 2 1 Phage minor structural protein GP20 APH PF01636.18 EME88370.1 - 0.00073 19.3 5.8 0.0037 17.0 0.0 3.1 2 2 0 2 2 2 1 Phosphotransferase enzyme family Cep57_CLD_2 PF14197.1 EME88370.1 - 0.0029 17.4 3.3 0.0029 17.4 2.3 2.5 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 BRE1 PF08647.6 EME88370.1 - 0.061 13.3 8.8 0.18 11.8 4.3 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase OTT_1508_deam PF14441.1 EME88370.1 - 0.17 11.7 1.8 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 OTT_1508-like deaminase DUF342 PF03961.8 EME88370.1 - 0.17 10.2 4.0 0.056 11.8 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 EME88370.1 - 0.53 9.2 11.4 0.074 12.0 5.0 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3573 PF12097.3 EME88370.1 - 0.61 8.6 2.0 0.95 8.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3373 PF11853.3 EME88370.1 - 0.68 8.3 3.0 0.99 7.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HALZ PF02183.13 EME88370.1 - 2.2 8.0 6.8 5.4 6.8 0.7 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper Wbp11 PF09429.5 EME88370.1 - 4.3 7.3 9.4 3.3 7.7 2.7 2.8 3 0 0 3 3 3 0 WW domain binding protein 11 Fungal_trans PF04082.13 EME88371.1 - 1.5e-32 112.5 0.0 2.5e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88371.1 - 4.5e-10 39.2 13.9 7.5e-10 38.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M41 PF01434.13 EME88372.1 - 2.3e-74 249.4 0.1 3.9e-74 248.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EME88372.1 - 2.5e-42 144.2 0.1 9.3e-42 142.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EME88372.1 - 1e-06 28.8 0.1 2.9e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EME88372.1 - 0.00015 21.5 0.1 0.00058 19.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME88372.1 - 0.00061 19.9 0.8 0.23 11.5 0.1 3.2 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EME88372.1 - 0.0023 18.7 0.0 0.0096 16.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EME88372.1 - 0.0043 16.7 1.2 0.02 14.6 0.4 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EME88372.1 - 0.0057 16.6 0.6 0.13 12.1 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 EME88372.1 - 0.0079 14.9 0.1 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EME88372.1 - 0.017 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EME88372.1 - 0.035 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EME88372.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4473 PF14747.1 EME88372.1 - 0.053 13.7 0.3 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) AAA_2 PF07724.9 EME88372.1 - 0.063 13.1 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EME88372.1 - 0.077 12.3 1.1 0.34 10.3 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EME88372.1 - 0.11 12.3 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EME88372.1 - 0.13 12.5 0.3 0.92 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME88372.1 - 0.16 11.9 0.2 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pmp3 PF01679.12 EME88373.1 - 4.1e-24 84.0 7.8 4.5e-24 83.8 5.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RseC_MucC PF04246.7 EME88373.1 - 0.14 11.6 0.3 0.15 11.6 0.2 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC HhH-GPD PF00730.20 EME88374.1 - 1.9e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_60s PF00428.14 EME88374.1 - 0.0067 16.7 12.1 0.17 12.2 1.6 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF2796 PF10986.3 EME88374.1 - 0.021 14.7 0.4 0.021 14.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) HHH PF00633.18 EME88374.1 - 0.045 13.4 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Fungal_trans PF04082.13 EME88375.1 - 2.1e-16 59.5 0.4 3.8e-16 58.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88375.1 - 1.1e-09 38.0 8.8 2.1e-09 37.1 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 EME88376.1 - 1.2e-12 47.7 0.1 2.7e-12 46.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME88376.1 - 3.5e-07 30.2 0.1 8.1e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GCD14 PF08704.5 EME88377.1 - 8.4e-09 35.2 0.0 6.7e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EME88377.1 - 1.4e-05 25.6 0.0 3.4e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EME88377.1 - 2.4e-05 25.1 0.1 5.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME88377.1 - 3.8e-05 23.3 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME88377.1 - 0.0043 17.0 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME88377.1 - 0.099 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EME88377.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_6 PF08030.7 EME88378.1 - 1.2e-08 35.0 0.0 5e-07 29.7 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EME88378.1 - 0.00054 20.5 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EME88378.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Cytochrom_B561 PF03188.11 EME88381.1 - 1e-10 41.6 18.9 3.5e-10 39.8 10.1 2.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EME88381.1 - 9.9e-06 25.5 0.3 1.8e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EME88381.1 - 1.4e-05 24.6 4.4 1.4e-05 24.6 3.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF3007 PF11460.3 EME88381.1 - 0.0051 16.8 0.1 0.0051 16.8 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3007) DUF373 PF04123.8 EME88381.1 - 0.55 9.2 5.6 0.86 8.5 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) IncA PF04156.9 EME88381.1 - 0.6 9.6 0.0 0.6 9.6 0.0 2.2 2 1 0 2 2 2 0 IncA protein UEV PF05743.8 EME88382.1 - 5.6e-35 119.6 0.0 9.6e-35 118.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EME88382.1 - 7.3e-15 54.3 0.7 1.6e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Vps23 core domain DSBA PF01323.15 EME88383.1 - 2.5e-24 85.8 0.0 2.9e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Kinesin PF00225.18 EME88384.1 - 6.7e-112 373.5 0.0 6.7e-112 373.5 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EME88384.1 - 8e-35 119.5 0.0 1.8e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 EME88384.1 - 0.00013 22.0 0.6 0.0048 16.9 0.0 3.5 4 0 0 4 4 4 1 FHA domain PH PF00169.24 EME88384.1 - 0.0034 17.5 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 PH domain AAA_22 PF13401.1 EME88384.1 - 0.024 14.7 0.4 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3819 PF12842.2 EME88384.1 - 0.37 10.4 6.1 1.1 8.9 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF106 PF01956.11 EME88384.1 - 2.3 7.7 3.9 5.5 6.4 2.7 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 IncA PF04156.9 EME88384.1 - 3.1 7.3 21.6 0.95 9.0 9.0 2.6 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EME88384.1 - 3.7 5.2 8.7 1.1 7.0 2.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EME88384.1 - 7.7 6.4 29.7 0.79 9.6 15.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Met_10 PF02475.11 EME88385.1 - 6e-49 166.3 0.0 7.3e-25 87.7 0.0 2.2 1 1 1 2 2 2 2 Met-10+ like-protein Hydantoinase_B PF02538.9 EME88385.1 - 0.1 10.7 0.0 7.1 4.7 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase adh_short PF00106.20 EME88386.1 - 5.9e-22 78.3 0.7 8.8e-22 77.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME88386.1 - 1.5e-09 37.9 0.2 3e-09 36.9 0.1 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME88386.1 - 9.6e-08 31.8 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME88386.1 - 1.6e-07 31.5 0.2 1.2e-06 28.6 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EME88386.1 - 4.4e-05 22.7 0.0 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Hexokinase_2 PF03727.11 EME88387.1 - 1.8e-67 227.0 0.1 9.4e-67 224.7 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EME88387.1 - 9e-66 221.1 0.3 2.6e-65 219.6 0.0 1.8 2 0 0 2 2 2 1 Hexokinase Mito_fiss_reg PF05308.6 EME88388.1 - 0.85 8.9 3.6 0.85 8.9 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EME88388.1 - 1.6 7.9 3.6 1.6 7.9 2.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Corona_S2 PF01601.11 EME88389.1 - 0.093 10.8 12.1 0.13 10.3 8.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein LSR PF05624.9 EME88389.1 - 1.2 8.9 26.7 2 8.2 18.5 1.3 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Aa_trans PF01490.13 EME88390.1 - 9.6e-35 119.8 32.3 1.1e-34 119.6 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2206 PF09971.4 EME88390.1 - 0.4 9.4 14.7 0.21 10.3 6.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) Spore_permease PF03845.8 EME88390.1 - 0.46 9.0 19.6 4 6.0 13.6 2.3 1 1 0 1 1 1 0 Spore germination protein Mcm10 PF09332.6 EME88391.1 - 0.16 11.2 3.7 7.8 5.7 1.7 2.7 2 1 0 2 2 2 0 Mcm10 replication factor Cpn60_TCP1 PF00118.19 EME88392.1 - 2.7e-145 484.7 1.3 3.1e-145 484.5 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 EME88392.1 - 0.025 14.2 0.7 0.89 9.1 0.0 2.9 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Chromo PF00385.19 EME88393.1 - 2e-12 46.5 4.2 2.3e-12 46.4 1.0 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EME88393.1 - 1.3e-05 24.8 0.0 4.5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain MFS_1 PF07690.11 EME88394.1 - 7.7e-28 97.2 36.4 8.3e-25 87.2 5.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME88394.1 - 7.7e-06 24.5 0.2 7.7e-06 24.5 0.1 2.4 2 1 1 3 3 3 1 MFS/sugar transport protein PIP5K PF01504.13 EME88395.1 - 6.4e-36 123.7 0.0 8.3e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Wbp11 PF09429.5 EME88396.1 - 1.3e-20 73.1 16.0 1.3e-20 73.1 11.1 3.0 3 1 0 3 3 3 1 WW domain binding protein 11 NAD_binding_6 PF08030.7 EME88397.1 - 4e-21 75.5 0.0 4.6e-19 68.8 0.0 2.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EME88397.1 - 3.7e-19 69.0 9.2 3.7e-19 69.0 6.4 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EME88397.1 - 3.7e-14 52.4 0.0 1.1e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EME88397.1 - 6.6e-05 23.4 0.0 0.079 13.5 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain An_peroxidase PF03098.10 EME88398.1 - 2.1e-60 204.6 0.0 1.8e-39 135.5 0.0 2.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EME88398.1 - 2.9e-08 32.6 0.0 4.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.4 EME88399.1 - 6e-100 334.1 2.7 6.2e-100 334.1 1.1 1.5 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Translin PF01997.11 EME88400.1 - 1.6e-53 181.2 0.0 1.9e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Translin family UvrD_C PF13361.1 EME88400.1 - 0.096 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Cu-oxidase_3 PF07732.10 EME88401.1 - 2.6e-20 72.3 1.3 2.6e-20 72.3 0.9 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME88401.1 - 2.5e-18 65.9 8.8 6.2e-18 64.6 1.4 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EME88401.1 - 1.8e-08 34.4 0.3 3.8e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 Multicopper oxidase Memo PF01875.12 EME88402.1 - 3.4e-71 239.3 0.0 4.6e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein PTR2 PF00854.16 EME88403.1 - 2.5e-26 92.3 3.1 4.8e-26 91.4 2.2 1.5 1 0 0 1 1 1 1 POT family DUF1404 PF07185.6 EME88403.1 - 0.13 11.8 4.9 0.27 10.8 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1404) IPP-2 PF04979.9 EME88404.1 - 0.041 14.1 1.0 0.048 13.9 0.3 1.4 1 1 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) OmpH PF03938.9 EME88404.1 - 0.099 12.5 0.9 0.16 11.8 0.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3049 PF11250.3 EME88405.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) SnoaL_2 PF12680.2 EME88407.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Fe-ADH PF00465.14 EME88408.1 - 5.3e-73 245.7 0.6 6e-73 245.5 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME88408.1 - 8.6e-15 54.7 0.1 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EME88408.1 - 0.56 9.0 2.7 0.73 8.7 0.6 2.1 1 1 0 2 2 2 0 3-dehydroquinate synthase Ribosomal_S3_C PF00189.15 EME88409.1 - 1.4e-16 60.4 0.1 2.8e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EME88409.1 - 1.2e-09 37.5 0.0 2.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 KH domain Fringe PF02434.11 EME88410.1 - 7e-09 35.2 0.0 9.4e-08 31.5 0.0 2.2 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EME88410.1 - 4.2e-05 23.1 0.7 7.9e-05 22.2 0.5 1.4 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EME88410.1 - 0.0005 19.7 0.7 0.001 18.7 0.5 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 EME88410.1 - 0.021 14.6 0.3 0.047 13.5 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain Asp_Glu_race PF01177.17 EME88412.1 - 8.6e-19 68.2 1.1 1e-18 68.0 0.8 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase HMGL-like PF00682.14 EME88412.1 - 0.017 14.7 0.1 0.39 10.3 0.0 2.4 1 1 1 2 2 2 0 HMGL-like ComA PF02679.10 EME88412.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.6 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) PEP_mutase PF13714.1 EME88412.1 - 0.062 12.5 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Epimerase PF01370.16 EME88413.1 - 1.2e-13 51.0 0.2 2.7e-13 49.9 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME88413.1 - 3.9e-11 42.1 0.0 8.5e-11 41.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME88413.1 - 8.8e-10 38.8 0.0 2.1e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME88413.1 - 7.1e-07 28.3 0.0 1.9e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EME88413.1 - 5.3e-05 22.5 0.0 8.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EME88413.1 - 0.0004 20.3 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EME88413.1 - 0.00089 18.2 0.0 0.0023 16.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EME88413.1 - 0.027 13.3 0.0 0.51 9.1 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EME88413.1 - 0.076 12.6 0.4 0.38 10.3 0.1 2.3 2 1 0 2 2 2 0 KR domain Use1 PF09753.4 EME88414.1 - 2.9e-07 30.1 10.2 1.2e-06 28.2 7.1 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4463 PF14703.1 EME88414.1 - 0.087 13.3 0.9 0.21 12.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Synaptobrevin PF00957.16 EME88414.1 - 0.18 11.4 0.1 0.18 11.4 0.0 3.2 4 0 0 4 4 4 0 Synaptobrevin Rabaptin PF03528.10 EME88414.1 - 0.57 10.1 7.6 0.29 11.0 2.9 2.2 2 0 0 2 2 2 0 Rabaptin Coatomer_E PF04733.9 EME88415.1 - 4.2e-56 190.2 3.7 4.9e-56 190.0 2.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EME88415.1 - 2e-07 31.2 8.1 0.0028 17.9 0.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EME88415.1 - 3e-07 30.4 0.1 0.079 13.1 0.2 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EME88415.1 - 2.2e-06 28.1 1.3 0.0042 17.7 0.1 4.6 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME88415.1 - 2.4e-06 26.8 0.1 0.0036 16.8 0.0 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME88415.1 - 1.5e-05 25.2 11.7 0.0018 18.7 0.1 5.8 2 1 5 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME88415.1 - 5.3e-05 23.0 3.8 0.011 15.6 0.3 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME88415.1 - 6.6e-05 22.5 9.3 0.0003 20.4 0.0 5.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME88415.1 - 0.00083 18.9 8.2 0.0036 16.9 0.1 4.5 5 1 0 6 6 6 1 TPR repeat TPR_8 PF13181.1 EME88415.1 - 0.0015 18.1 0.4 0.031 14.0 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EME88415.1 - 0.025 13.6 3.3 0.12 11.3 1.7 2.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EME88415.1 - 0.04 14.3 5.5 2.5 8.7 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat YfdX PF10938.3 EME88415.1 - 0.051 13.2 1.4 0.39 10.3 0.2 2.7 2 1 0 2 2 2 0 YfdX protein TPR_6 PF13174.1 EME88415.1 - 0.059 13.8 2.4 21 5.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EME88415.1 - 0.12 12.2 0.3 8.9 6.3 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EME88415.1 - 0.51 10.2 3.9 1.3 8.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MMR_HSR1_C PF08438.5 EME88416.1 - 3.2e-28 98.1 0.0 5.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EME88416.1 - 3.6e-13 49.4 0.0 9.3e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME88416.1 - 0.0036 16.5 0.0 0.0088 15.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B VirB8 PF04335.8 EME88416.1 - 0.0075 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 VirB8 protein AAA_16 PF13191.1 EME88416.1 - 0.0079 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EME88416.1 - 0.028 14.2 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family KTI12 PF08433.5 EME88416.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EME88416.1 - 0.1 12.5 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EME88416.1 - 0.14 12.4 0.0 0.64 10.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Pkinase PF00069.20 EME88418.1 - 2.2e-52 177.7 0.0 3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME88418.1 - 1.2e-16 60.5 0.0 2.8e-16 59.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EME88418.1 - 0.00014 21.6 0.0 0.00036 20.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EME88418.1 - 0.069 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EME88418.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EME88418.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hydrolase_6 PF13344.1 EME88419.1 - 8.6e-25 86.5 0.0 1.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME88419.1 - 1.4e-12 47.1 0.0 7.2e-12 44.8 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EME88419.1 - 0.00099 19.3 0.0 0.92 9.7 0.0 3.2 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME88419.1 - 0.043 14.2 0.0 2.8 8.3 0.0 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 EME88421.1 - 2e-45 155.1 0.0 2.7e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arf PF00025.16 EME88423.1 - 2.9e-75 251.3 0.1 3.2e-75 251.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME88423.1 - 1.6e-13 50.2 0.0 2.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME88423.1 - 1.8e-13 50.1 0.0 2.1e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME88423.1 - 7.4e-11 41.3 1.3 4.4e-07 28.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME88423.1 - 1.9e-09 37.0 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME88423.1 - 1.9e-09 38.0 0.0 2.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME88423.1 - 2.1e-06 27.6 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME88423.1 - 2.5e-05 23.8 0.0 0.0036 16.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EME88423.1 - 0.0039 16.4 1.1 0.021 14.0 0.8 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EME88423.1 - 0.0058 15.4 0.1 0.043 12.5 0.0 2.3 2 1 0 2 2 2 1 ArgK protein DUF3986 PF13143.1 EME88423.1 - 0.086 13.2 0.2 0.26 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Ferric_reduct PF01794.14 EME88424.1 - 3.7e-18 65.8 14.1 3.7e-18 65.8 9.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EME88424.1 - 5.1e-13 49.2 0.0 4.8e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EME88424.1 - 0.00011 22.0 0.0 0.52 10.2 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EME88424.1 - 0.019 15.5 0.0 0.054 14.0 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF2101 PF09874.4 EME88424.1 - 1.6 8.1 3.8 5.5 6.4 0.7 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) AAA PF00004.24 EME88425.1 - 4e-40 137.0 0.0 8.5e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME88425.1 - 0.00013 21.1 0.0 0.00046 19.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EME88425.1 - 0.00015 21.7 0.3 0.0076 16.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EME88425.1 - 0.00016 21.3 0.3 0.00078 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EME88425.1 - 0.0005 20.2 0.2 0.014 15.5 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EME88425.1 - 0.0026 17.7 1.6 0.011 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EME88425.1 - 0.0038 16.4 0.2 0.04 13.1 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EME88425.1 - 0.0058 15.8 0.1 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EME88425.1 - 0.0066 15.3 0.0 0.016 14.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EME88425.1 - 0.0092 15.8 0.1 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME88425.1 - 0.013 15.2 0.3 0.032 13.9 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EME88425.1 - 0.02 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EME88425.1 - 0.044 13.1 1.2 0.38 10.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EME88425.1 - 0.047 13.5 0.2 0.32 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EME88425.1 - 0.21 12.4 0.2 0.21 12.4 0.1 3.2 2 2 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EME88425.1 - 0.24 10.9 5.2 0.44 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Vfa1 PF08432.5 EME88425.1 - 9.4 6.2 11.3 18 5.2 7.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HET PF06985.6 EME88426.1 - 8.3e-24 84.3 0.4 6.2e-23 81.4 0.3 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 EME88427.1 - 4.7e-07 29.6 0.0 7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME88427.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EME88427.1 - 0.0036 16.3 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_18 PF12847.2 EME88427.1 - 0.018 15.5 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EME88427.1 - 0.1 11.8 0.0 0.34 10.1 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain SET PF00856.23 EME88429.1 - 2.6e-09 37.5 0.0 9.6e-09 35.7 0.0 2.0 2 1 0 2 2 2 1 SET domain Bac_surface_Ag PF01103.18 EME88431.1 - 3e-38 132.0 0.1 3.9e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Ish1 PF10281.4 EME88433.1 - 1.2e-50 169.1 19.8 2.6e-13 49.7 0.2 5.6 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EME88433.1 - 2.2e-10 39.9 0.0 0.22 11.1 0.0 4.4 4 0 0 4 4 4 4 HeH/LEM domain SAP PF02037.22 EME88433.1 - 3e-05 23.3 0.0 0.94 9.0 0.0 4.2 3 1 1 4 4 4 2 SAP domain Slx4 PF09494.5 EME88433.1 - 0.0027 17.3 1.8 1.2 8.9 0.0 3.2 4 0 0 4 4 4 2 Slx4 endonuclease APC2 PF08672.6 EME88433.1 - 0.0028 17.8 0.2 45 4.3 0.0 4.2 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 SAM_2 PF07647.12 EME88433.1 - 0.43 10.4 2.4 39 4.1 0.0 3.7 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) MT0933_antitox PF14013.1 EME88433.1 - 2 8.5 9.3 3.5 7.8 0.2 3.4 3 0 0 3 3 3 0 MT0933-like antitoxin protein DUF3260 PF11658.3 EME88434.1 - 0.016 13.3 0.1 0.033 12.3 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3260) SnoaL_4 PF13577.1 EME88435.1 - 2.1e-16 59.9 0.0 2.4e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain S1FA PF04689.8 EME88439.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DAGK_cat PF00781.19 EME88440.1 - 1.2e-12 47.4 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MFS_1 PF07690.11 EME88441.1 - 4.4e-12 45.3 17.2 9.9e-12 44.2 11.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SdpI PF13630.1 EME88441.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 2.0 2 0 0 2 2 2 1 SdpI/YhfL protein family Ras PF00071.17 EME88442.1 - 5.1e-40 136.5 0.0 2.5e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EME88442.1 - 1.6e-16 60.9 0.0 2.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME88442.1 - 1.4e-13 50.4 0.0 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EME88442.1 - 0.0002 20.5 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EME88442.1 - 0.00037 20.6 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EME88442.1 - 0.00065 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EME88442.1 - 0.0028 17.6 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EME88442.1 - 0.0085 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SRPRB PF09439.5 EME88442.1 - 0.018 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EME88442.1 - 0.018 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_28 PF13521.1 EME88442.1 - 0.031 14.2 0.4 0.073 13.0 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EME88442.1 - 0.035 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EME88442.1 - 0.037 13.5 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EME88442.1 - 0.038 13.6 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EME88442.1 - 0.047 12.8 0.1 0.1 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Flavin_Reduct PF01613.13 EME88443.1 - 7.2e-20 71.3 0.3 1e-19 70.8 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain McyA_C PF12593.3 EME88443.1 - 2.4 7.9 9.3 11 5.8 2.0 2.4 1 1 1 2 2 2 0 Microcystin synthetase C terminal MFS_1 PF07690.11 EME88444.1 - 1.3e-23 83.2 53.4 3.7e-18 65.3 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EME88445.1 - 5.3e-08 32.0 0.3 1.4e-07 30.6 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88445.1 - 4.9e-06 26.3 9.1 9.9e-06 25.3 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT PF03061.17 EME88447.1 - 1.8e-10 40.7 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily GFO_IDH_MocA PF01408.17 EME88448.1 - 4.1e-09 36.9 0.2 2.6e-08 34.4 0.1 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EME88448.1 - 0.034 13.9 0.1 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain GARS_N PF02844.10 EME88448.1 - 0.15 12.5 0.1 3.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain adh_short PF00106.20 EME88449.1 - 1.6e-31 109.4 0.0 2.2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME88449.1 - 5.2e-28 98.4 0.1 8.9e-28 97.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME88449.1 - 4.9e-16 58.9 0.0 6.6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EME88449.1 - 0.0092 15.6 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EME88449.1 - 0.028 14.2 0.2 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3Beta_HSD PF01073.14 EME88449.1 - 0.033 12.8 0.1 0.043 12.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cutinase PF01083.17 EME88450.1 - 5.1e-50 169.6 1.0 6e-50 169.4 0.7 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EME88450.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EME88450.1 - 0.017 14.9 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 EME88450.1 - 0.036 13.4 0.1 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 EME88450.1 - 0.055 12.8 0.4 0.076 12.4 0.2 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1944 PF09175.5 EME88453.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) COesterase PF00135.23 EME88455.1 - 7.6e-14 51.3 0.0 8.7e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family SLAC1 PF03595.12 EME88457.1 - 3.5e-76 256.0 42.2 3.9e-76 255.8 29.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel His_Phos_2 PF00328.17 EME88460.1 - 3.3e-118 395.0 0.3 4.1e-118 394.6 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EME88460.1 - 4.3e-07 29.6 0.0 7.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EME88461.1 - 1.1e-68 230.8 1.0 1.7e-68 230.3 0.7 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EME88461.1 - 3.4e-13 48.9 24.3 0.002 17.9 0.1 8.6 9 0 0 9 9 9 4 WD domain, G-beta repeat Utp12 PF04003.7 EME88461.1 - 0.00034 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.5 EME88461.1 - 0.037 13.7 0.1 0.057 13.1 0.1 1.2 1 0 0 1 1 1 0 UTP15 C terminal UPF0016 PF01169.14 EME88463.1 - 2.7e-42 142.7 26.6 1.2e-22 79.8 4.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Aldo_ket_red PF00248.16 EME88465.1 - 4.1e-62 209.5 0.0 5.3e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAR2 PF05282.6 EME88466.1 - 7.2e-81 271.9 0.0 9.3e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein COesterase PF00135.23 EME88467.1 - 2.4e-90 303.8 0.0 3.2e-83 280.2 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EME88467.1 - 7.8e-12 45.2 0.4 3e-11 43.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME88467.1 - 1e-05 25.3 0.1 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME88467.1 - 0.00017 21.5 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME88467.1 - 0.0041 16.3 0.6 0.0071 15.5 0.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_25 PF13649.1 EME88468.1 - 7.2e-09 35.9 0.1 2.1e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME88468.1 - 1.3e-08 35.1 0.4 2.8e-08 34.1 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME88468.1 - 3e-08 33.4 0.1 1e-07 31.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME88468.1 - 7e-08 33.0 0.3 1.3e-07 32.1 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME88468.1 - 1.8e-05 25.1 0.2 7.6e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EME88468.1 - 0.00011 21.4 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EME88468.1 - 0.00064 19.4 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME88468.1 - 0.0059 15.7 0.1 0.0069 15.5 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EME88468.1 - 0.0091 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 EME88468.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 3Beta_HSD PF01073.14 EME88469.1 - 8.1e-17 60.8 0.0 1e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME88469.1 - 9.4e-16 57.9 0.0 1.7e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME88469.1 - 1.5e-12 47.9 0.1 8.3e-12 45.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME88469.1 - 4.5e-10 38.8 0.0 5.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EME88469.1 - 3.2e-05 23.9 0.2 5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME88469.1 - 0.00017 21.2 0.4 0.00035 20.2 0.3 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EME88469.1 - 0.00063 19.0 0.1 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase_Csub PF13950.1 EME88469.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit F420_oxidored PF03807.12 EME88469.1 - 0.092 13.1 0.1 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FA_hydroxylase PF04116.8 EME88470.1 - 6.3e-17 62.0 18.7 6.3e-17 62.0 12.9 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Pkinase PF00069.20 EME88471.1 - 5.5e-34 117.4 0.1 8.4e-16 57.8 0.1 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EME88471.1 - 6.1e-10 38.6 0.4 1.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Drf_FH1 PF06346.7 EME88474.1 - 0.0012 18.4 39.9 0.0012 18.4 27.6 2.1 2 0 0 2 2 2 2 Formin Homology Region 1 Peptidase_M28 PF04389.12 EME88476.1 - 5.2e-32 111.0 0.1 9.4e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME88476.1 - 5e-11 42.1 0.3 1e-10 41.1 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EME88476.1 - 0.00011 21.7 0.5 0.0013 18.3 0.1 2.4 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1349 PF07081.6 EME88480.1 - 4.2e-31 107.7 0.4 9.4e-31 106.5 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) GFA PF04828.9 EME88481.1 - 2e-20 72.5 8.8 9.5e-10 38.3 2.6 3.0 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EME88481.1 - 0.22 11.4 0.1 0.22 11.4 0.1 3.6 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like PAP_assoc PF03828.14 EME88482.1 - 5.4e-10 39.0 0.2 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EME88482.1 - 5.2e-05 23.5 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Luciferase_N PF05295.6 EME88482.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain ATG22 PF11700.3 EME88483.1 - 0.046 12.2 0.8 0.068 11.6 0.6 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like CoA_binding_3 PF13727.1 EME88483.1 - 1.7 8.4 4.4 2.7 7.8 3.0 1.2 1 0 0 1 1 1 0 CoA-binding domain HMA PF00403.21 EME88485.1 - 1.8e-13 50.4 0.0 3.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EME88485.1 - 1.1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PsiB PF06290.6 EME88486.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) FAD_binding_4 PF01565.18 EME88487.1 - 4.9e-21 74.6 0.2 8e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EME88487.1 - 0.13 12.1 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like Anoctamin PF04547.7 EME88489.1 - 3.6e-116 388.5 0.0 4.3e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel adh_short PF00106.20 EME88490.1 - 7.5e-18 65.0 0.7 4e-15 56.1 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EME88490.1 - 5.9e-06 26.2 0.0 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME88490.1 - 1.1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain zf-MYND PF01753.13 EME88491.1 - 2.6e-11 43.1 11.5 3.9e-11 42.6 8.0 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EME88491.1 - 0.16 11.8 5.0 0.36 10.7 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 EME88491.1 - 9.1 5.6 7.7 0.24 10.7 0.9 1.7 2 0 0 2 2 2 0 Life-span regulatory factor AA_permease PF00324.16 EME88492.1 - 3.2e-112 375.3 38.7 4e-112 375.0 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME88492.1 - 9.3e-23 80.4 43.3 1.3e-22 80.0 30.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 EME88492.1 - 0.1 11.9 0.1 0.1 11.9 0.0 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3487) DASH_Duo1 PF08651.5 EME88494.1 - 9.3e-27 92.4 0.8 1.9e-26 91.4 0.6 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1366 PF07104.6 EME88494.1 - 0.041 13.5 0.2 0.041 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Macoilin PF09726.4 EME88494.1 - 0.12 10.5 14.3 0.16 10.2 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein NPV_P10 PF05531.7 EME88494.1 - 0.23 11.7 1.4 0.57 10.4 1.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3340 PF11818.3 EME88494.1 - 1 9.2 12.3 0.41 10.5 6.8 1.6 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF4391 PF14335.1 EME88494.1 - 1.2 8.4 11.0 0.59 9.4 2.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4391) DUF1840 PF08895.6 EME88494.1 - 1.9 8.5 7.6 0.52 10.3 2.6 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1840) DUF2025 PF09634.5 EME88496.1 - 0.045 13.4 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) Vps52 PF04129.7 EME88497.1 - 0.15 10.5 0.0 0.26 9.7 0.0 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family MFS_1 PF07690.11 EME88498.1 - 5.9e-27 94.3 23.9 3.8e-26 91.6 17.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA PF00004.24 EME88499.1 - 7.4e-21 74.7 0.0 4.5e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME88499.1 - 1.7e-05 24.9 0.0 0.005 16.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME88499.1 - 0.00032 20.3 0.1 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EME88499.1 - 0.00066 20.4 0.0 0.002 18.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EME88499.1 - 0.0016 18.4 0.2 0.024 14.6 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EME88499.1 - 0.0041 16.8 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps36_ESCRT-II PF11605.3 EME88499.1 - 0.0051 16.5 0.0 0.033 14.0 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 TIP49 PF06068.8 EME88499.1 - 0.0072 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EME88499.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME88499.1 - 0.029 14.6 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EME88499.1 - 0.03 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EME88499.1 - 0.042 13.0 0.2 0.14 11.3 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EME88499.1 - 0.061 12.7 0.0 0.17 11.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 EME88499.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2296 PF10058.4 EME88502.1 - 2.8e-20 71.8 0.2 4.9e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4200 PF13863.1 EME88502.1 - 0.025 14.5 2.0 2.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4463 PF14703.1 EME88502.1 - 0.032 14.7 1.0 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF2899 PF11449.3 EME88502.1 - 0.06 12.5 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) ALIX_LYPXL_bnd PF13949.1 EME88502.1 - 0.067 12.1 0.2 0.067 12.1 0.1 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV zf-Sec23_Sec24 PF04810.10 EME88502.1 - 0.51 9.9 3.0 1.8 8.1 2.1 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger DUF605 PF04652.11 EME88502.1 - 1.6 8.0 11.2 2.2 7.5 7.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF336 PF03928.9 EME88503.1 - 2.1e-30 105.2 1.0 2.4e-30 105.0 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) F-box-like PF12937.2 EME88504.1 - 0.0014 18.2 0.5 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME88504.1 - 0.027 14.1 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain HTH_29 PF13551.1 EME88505.1 - 3.6e-07 30.2 0.0 8.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EME88505.1 - 1.8e-05 24.5 0.1 0.00079 19.2 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EME88505.1 - 0.00011 22.9 1.5 0.0028 18.4 0.0 2.9 3 1 1 4 4 4 1 Homeodomain-like domain PAX PF00292.13 EME88505.1 - 0.0045 16.6 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 'Paired box' domain HTH_38 PF13936.1 EME88505.1 - 0.035 13.6 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 EME88505.1 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Trp_repressor PF01371.14 EME88505.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein WD40 PF00400.27 EME88505.1 - 0.086 12.7 0.3 0.26 11.2 0.2 1.8 1 1 0 1 1 1 0 WD domain, G-beta repeat PEP_mutase PF13714.1 EME88506.1 - 4.3e-61 206.1 0.6 4.8e-61 206.0 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.19 EME88506.1 - 0.018 14.3 0.3 0.12 11.5 0.2 2.2 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel ComA PF02679.10 EME88506.1 - 0.11 11.4 0.2 0.42 9.5 0.1 1.8 1 1 1 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) Inositol_P PF00459.20 EME88507.1 - 5.8e-77 258.6 0.0 6.6e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 EME88508.1 - 5e-22 77.7 0.0 9.2e-22 76.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EME88508.1 - 3.7e-14 52.9 0.0 5.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 EME88508.1 - 0.038 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_7 PF13241.1 EME88508.1 - 0.06 13.5 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sugar_tr PF00083.19 EME88509.1 - 4.1e-128 427.7 31.7 4.7e-128 427.5 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88509.1 - 5.5e-20 71.3 40.6 5.5e-20 71.3 28.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.7 EME88509.1 - 0.12 12.0 2.8 1.3 8.7 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) AP_endonuc_2 PF01261.19 EME88510.1 - 1e-30 106.6 0.2 2e-30 105.7 0.1 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Zn_clus PF00172.13 EME88512.1 - 2.6e-07 30.4 12.0 4.4e-07 29.7 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME88512.1 - 1.9e-06 26.9 0.1 3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHquinase_I PF01487.10 EME88513.1 - 3.6e-29 102.0 0.0 8.4e-29 100.8 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EME88513.1 - 4.3e-19 68.3 0.1 1.1e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EME88513.1 - 5.5e-16 58.8 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EME88513.1 - 3.5e-11 43.3 0.0 8.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_5 PF07728.9 EME88513.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) F420_oxidored PF03807.12 EME88513.1 - 0.092 13.1 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1100 PF06500.6 EME88513.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Arylsulfotran_2 PF14269.1 EME88514.1 - 7.1e-58 196.1 1.0 1e-57 195.5 0.7 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME88514.1 - 6.5e-23 80.9 0.4 6.5e-23 80.9 0.3 1.5 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) AA_permease PF00324.16 EME88515.1 - 4.3e-126 421.0 38.7 5.4e-126 420.7 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EME88515.1 - 3.7e-44 150.9 43.3 4.5e-44 150.6 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EME88515.1 - 0.031 14.5 0.0 0.031 14.5 0.0 2.9 3 1 0 3 3 3 0 Divalent cation transporter RINGv PF12906.2 EME88517.1 - 2.3e-06 27.5 4.5 4.3e-06 26.6 3.1 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EME88517.1 - 0.00027 20.8 3.2 0.00063 19.6 2.2 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EME88517.1 - 0.00074 19.2 4.1 0.0013 18.5 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EME88517.1 - 0.31 10.7 2.0 0.64 9.7 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME88517.1 - 6.1 6.9 6.4 2.2 8.3 2.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 EME88518.1 - 3.2e-71 239.5 0.1 3.2e-71 239.5 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME88518.1 - 3.1e-15 55.8 0.0 7.9e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME88518.1 - 4.3e-05 23.4 4.8 0.00021 21.1 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EME88518.1 - 0.0021 17.5 0.0 0.022 14.2 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EME88518.1 - 0.024 14.2 0.0 0.024 14.2 0.0 3.2 2 1 0 3 3 3 0 AAA domain bZIP_1 PF00170.16 EME88521.1 - 1.8e-09 37.4 8.3 7.2e-09 35.4 5.8 2.0 1 1 0 1 1 1 1 bZIP transcription factor DUF501 PF04417.7 EME88521.1 - 0.0071 16.1 1.6 0.011 15.6 0.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF501) Adeno_PIX PF03955.9 EME88521.1 - 0.52 10.8 3.4 0.29 11.6 0.5 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) RNase_T PF00929.19 EME88522.1 - 4.4e-22 79.1 0.1 5.1e-22 78.9 0.1 1.0 1 0 0 1 1 1 1 Exonuclease F-box PF00646.28 EME88523.1 - 0.016 14.8 6.7 1.2 8.8 0.2 3.3 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EME88523.1 - 0.041 13.6 0.1 0.041 13.6 0.0 3.5 4 0 0 4 4 4 0 F-box-like Ribosomal_L12 PF00542.14 EME88523.1 - 0.071 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Usp PF00582.21 EME88525.1 - 5.3e-21 75.2 0.0 6.7e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DnaJ PF00226.26 EME88526.1 - 2.5e-20 71.9 1.0 2.5e-20 71.9 0.7 2.6 3 1 0 3 3 3 1 DnaJ domain TRM PF02005.11 EME88527.1 - 1.1e-108 363.5 0.0 2e-95 319.8 0.0 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EME88527.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EME88527.1 - 0.018 14.4 0.1 0.059 12.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Gamma-thionin PF00304.15 EME88530.1 - 0.12 12.4 0.6 0.19 11.7 0.4 1.2 1 0 0 1 1 1 0 Gamma-thionin family Defensin_beta PF00711.14 EME88530.1 - 0.19 11.6 3.8 0.3 11.0 2.6 1.3 1 0 0 1 1 1 0 Beta defensin Thiolase_N PF00108.18 EME88531.1 - 9.8e-76 254.2 1.6 1.4e-75 253.6 1.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EME88531.1 - 5.8e-44 148.4 0.3 3e-43 146.1 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EME88531.1 - 0.00031 20.3 0.9 0.0008 18.9 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF3245 PF11595.3 EME88532.1 - 0.0022 18.3 6.5 0.0022 18.3 4.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.5 EME88533.1 - 1.6e-78 262.7 1.1 1.6e-78 262.7 0.7 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EME88533.1 - 2.8e-20 72.4 0.0 6.9e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EME88533.1 - 1.7e-08 33.9 0.2 3.9e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EME88533.1 - 0.00044 19.8 1.4 0.023 14.2 0.2 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EME88533.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EME88533.1 - 0.029 13.8 0.0 0.14 11.6 0.0 2.1 1 1 1 2 2 2 0 RimK-like ATP-grasp domain RPE65 PF03055.10 EME88534.1 - 2.9e-114 382.3 0.0 3.5e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Bacteriocin_IIc PF10439.4 EME88536.1 - 0.003 17.6 7.8 0.003 17.6 5.4 2.6 1 1 1 2 2 2 1 Bacteriocin class II with double-glycine leader peptide DUF883 PF05957.8 EME88536.1 - 0.039 14.3 16.9 0.057 13.8 1.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TraT PF05818.7 EME88536.1 - 0.57 9.5 4.5 1.4 8.2 3.1 1.7 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein RRM_3 PF08777.6 EME88536.1 - 0.66 9.8 4.4 0.33 10.8 1.2 1.9 2 1 0 2 2 2 0 RNA binding motif Gly-zipper_Omp PF13488.1 EME88536.1 - 0.95 9.1 26.1 12 5.6 2.4 3.1 1 1 1 2 2 2 0 Glycine zipper MFS_1 PF07690.11 EME88537.1 - 5.4e-38 130.5 23.8 4.8e-37 127.4 16.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_transf_90 PF05686.7 EME88538.1 - 3.8e-08 32.4 0.0 4.4e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Imm32 PF15579.1 EME88538.1 - 0.067 12.7 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 32 P16-Arc PF04699.9 EME88540.1 - 4e-58 195.7 0.0 4.6e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Secretin_N PF03958.12 EME88540.1 - 0.092 12.9 0.8 3 8.0 0.5 2.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain CN_hydrolase PF00795.17 EME88541.1 - 3.9e-25 88.2 0.0 5.2e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Paf67 PF10255.4 EME88542.1 - 1.6e-148 494.9 0.0 1.8e-148 494.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EME88542.1 - 0.00063 19.4 0.1 0.0036 17.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EME88542.1 - 0.0061 16.1 0.1 0.032 13.8 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EME88542.1 - 0.034 14.0 1.3 0.12 12.3 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cyclin_N PF00134.18 EME88543.1 - 8.2e-05 22.1 0.0 0.021 14.3 0.0 2.4 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EME88543.1 - 0.049 13.4 0.0 3.1 7.6 0.0 2.6 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EME88543.1 - 0.07 13.0 0.5 0.35 10.8 0.0 2.3 2 1 0 2 2 2 0 Cyclin, C-terminal domain MFS_1 PF07690.11 EME88546.1 - 9.4e-22 77.1 50.0 5.3e-14 51.6 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME88546.1 - 1.7e-10 39.9 13.8 1.7e-07 30.0 0.5 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein RALF PF05498.6 EME88547.1 - 6.9e-13 49.2 2.5 9.4e-13 48.7 1.7 1.2 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) Aminotran_1_2 PF00155.16 EME88548.1 - 2.5e-41 141.8 0.0 3e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME88548.1 - 0.00031 19.9 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Lactamase_B_2 PF12706.2 EME88550.1 - 1.1e-38 132.7 0.1 1.4e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EME88550.1 - 2.9e-11 43.3 0.0 4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EME88550.1 - 0.0027 17.3 1.0 0.019 14.6 0.3 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily ADH_zinc_N PF00107.21 EME88552.1 - 2.6e-15 56.1 0.1 5e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME88552.1 - 0.0049 16.6 0.1 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain BTB PF00651.26 EME88553.1 - 2.4e-06 27.4 0.0 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Glycos_transf_N PF04413.11 EME88553.1 - 0.023 13.8 0.0 0.065 12.3 0.0 1.8 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) TPR_11 PF13414.1 EME88554.1 - 4.7e-06 26.1 0.8 1.5e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EME88554.1 - 1.7e-05 24.3 0.2 0.0037 17.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.1 EME88554.1 - 6.2e-05 23.0 0.6 0.00033 20.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME88554.1 - 0.00034 20.7 0.3 0.0028 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.1 EME88554.1 - 0.0014 18.5 3.5 0.021 14.7 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EME88554.1 - 0.0034 17.0 0.1 0.15 11.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.7 EME88554.1 - 0.0045 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EME88554.1 - 0.0053 16.3 0.4 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EME88554.1 - 0.0067 16.1 0.0 0.03 14.0 0.0 2.2 1 1 0 1 1 1 1 Part of AAA domain TPR_1 PF00515.23 EME88554.1 - 0.0086 15.6 0.2 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME88554.1 - 0.058 14.0 1.9 0.085 13.5 0.1 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME88554.1 - 0.062 13.9 0.6 0.44 11.3 0.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat Cauli_DNA-bind PF03310.8 EME88554.1 - 0.35 10.7 6.2 1.8 8.4 0.2 2.6 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein Ras PF00071.17 EME88557.1 - 7.7e-50 168.4 0.0 8.9e-50 168.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME88557.1 - 6.5e-16 58.9 0.0 1.2e-15 58.0 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EME88557.1 - 3.6e-07 29.5 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME88557.1 - 0.00016 21.1 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME88557.1 - 0.0068 15.5 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EME88557.1 - 0.0084 15.5 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EME88557.1 - 0.026 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EME88557.1 - 0.075 12.9 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EME88557.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NST1 PF13945.1 EME88558.1 - 1.2e-55 188.5 0.0 1.2e-55 188.5 0.0 5.0 4 1 2 6 6 6 1 Salt tolerance down-regulator MIP-T3 PF10243.4 EME88558.1 - 2.6e-05 22.9 74.5 2.6e-05 22.9 51.7 2.9 2 2 0 2 2 2 1 Microtubule-binding protein MIP-T3 DASH_Dad4 PF08650.5 EME88559.1 - 1e-26 92.6 3.0 1.1e-26 92.4 2.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 EME88559.1 - 0.014 15.3 0.3 0.016 15.1 0.2 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Pecanex_C PF05041.10 EME88559.1 - 0.029 13.4 0.1 0.032 13.2 0.1 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) DASH_Dad1 PF08649.5 EME88559.1 - 0.22 11.2 3.0 0.29 10.8 2.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Sec63 PF02889.11 EME88560.1 - 1.2e-151 504.3 0.0 4.5e-94 315.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EME88560.1 - 4.5e-55 185.7 0.3 1e-28 99.9 0.5 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EME88560.1 - 4.7e-17 62.4 0.0 2.9e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EME88560.1 - 1.8e-16 59.7 0.0 2.5e-07 30.4 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EME88560.1 - 2.4e-09 37.4 0.0 0.0032 17.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EME88560.1 - 6.5e-06 25.8 0.0 0.021 14.5 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain SNF2_N PF00176.18 EME88560.1 - 6.8e-06 25.0 0.9 0.087 11.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Alba PF01918.16 EME88560.1 - 0.1 12.2 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Alba Pyr_redox_3 PF13738.1 EME88562.1 - 4.9e-23 82.2 0.0 2.6e-22 79.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME88562.1 - 4.5e-13 48.2 0.1 8.9e-06 24.1 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME88562.1 - 1.7e-11 43.6 0.1 3.6e-09 36.0 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EME88562.1 - 4.8e-09 36.3 0.0 1.5e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME88562.1 - 7.6e-05 21.7 0.0 0.00099 18.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EME88562.1 - 0.00013 21.8 0.2 0.00067 19.6 0.1 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME88562.1 - 0.00077 19.2 0.1 0.35 10.6 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EME88562.1 - 0.0016 17.4 0.5 0.0041 16.0 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EME88562.1 - 0.14 11.0 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EME88562.1 - 0.15 11.0 0.1 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RRM_5 PF13893.1 EME88564.1 - 0.013 15.2 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EME88564.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_1 PF00076.17 EME88564.1 - 0.092 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME88564.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2458 PF10454.4 EME88566.1 - 5.4e-29 101.0 0.2 7.1e-29 100.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) COX14 PF14880.1 EME88567.1 - 1.2e-15 56.8 0.1 3.2e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF1844 PF08899.6 EME88568.1 - 0.065 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) RIC1 PF07064.8 EME88568.1 - 0.071 12.5 0.2 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 RIC1 Glyco_hydro_88 PF07470.8 EME88569.1 - 2.9e-65 220.5 7.7 3.7e-65 220.1 5.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prenyltrans_2 PF13249.1 EME88569.1 - 0.0063 16.9 0.9 0.086 13.2 0.0 2.8 3 0 0 3 3 3 1 Prenyltransferase-like Zn_clus PF00172.13 EME88570.1 - 3.6e-10 39.5 5.1 8.3e-10 38.4 3.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME88570.1 - 0.036 12.9 0.3 6.3 5.5 0.1 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain Mgm101p PF06420.7 EME88571.1 - 2e-88 294.1 0.0 2.3e-88 293.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.8 EME88572.1 - 1e-07 31.6 6.2 1.3e-07 31.3 4.3 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EME88572.1 - 0.0035 17.0 3.8 0.035 13.8 0.7 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EME88572.1 - 0.0044 17.0 2.6 0.0055 16.7 1.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF3045 PF11243.3 EME88572.1 - 0.032 14.4 0.2 0.035 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Pet191_N PF10203.4 EME88572.1 - 0.17 11.9 2.6 0.34 10.9 1.8 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 BPL_N PF09825.4 EME88573.1 - 2.7e-128 427.8 0.0 3.8e-128 427.3 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EME88573.1 - 7.1e-18 64.8 0.0 1.3e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MFS_1 PF07690.11 EME88574.1 - 4.4e-22 78.2 78.2 1.5e-15 56.7 29.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Bul1_C PF04426.7 EME88575.1 - 4.5e-05 22.7 0.1 7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus adh_short_C2 PF13561.1 EME88576.1 - 7.9e-16 58.5 0.0 1.1e-15 58.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME88576.1 - 2.8e-09 37.0 0.1 1.2e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Oxysterol_BP PF01237.13 EME88577.1 - 6.3e-88 294.6 0.5 7.6e-88 294.3 0.4 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3752 PF12572.3 EME88577.1 - 0.0081 16.2 2.7 0.016 15.3 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) DsrD PF08679.6 EME88577.1 - 0.012 15.6 0.3 0.035 14.0 0.2 1.8 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Cass2 PF14526.1 EME88577.1 - 0.076 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Integron-associated effector binding protein Not1 PF04054.10 EME88578.1 - 7.4e-97 324.5 0.2 2.1e-96 323.1 0.2 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EME88578.1 - 4.6e-43 146.4 5.3 6.3e-43 145.9 2.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Peptidase_S24 PF00717.18 EME88580.1 - 8.2e-09 34.9 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like IBR PF01485.16 EME88581.1 - 7.2e-17 61.0 34.5 2.2e-09 37.0 4.5 4.1 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EME88581.1 - 0.0029 17.2 3.1 0.0029 17.2 2.2 4.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME88581.1 - 0.0055 16.7 2.5 0.0055 16.7 1.8 4.4 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) PhnA_Zn_Ribbon PF08274.7 EME88581.1 - 0.27 11.0 0.3 0.27 11.0 0.2 3.9 4 0 0 4 4 4 0 PhnA Zinc-Ribbon FCH PF00611.18 EME88582.1 - 4.1e-18 65.3 0.0 1.8e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EME88582.1 - 9.3e-13 47.3 0.0 3.5e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EME88582.1 - 1.7e-12 46.6 0.0 9.1e-11 41.0 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EME88582.1 - 8.4e-11 41.2 0.0 2e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1768 PF08719.6 EME88583.1 - 2.8e-38 131.1 5.9 2.9e-37 127.8 4.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) DUF2717 PF10911.3 EME88585.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Pterin_4a PF01329.14 EME88587.1 - 4.5e-28 96.8 0.6 4.8e-28 96.7 0.4 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HisG_C PF08029.6 EME88588.1 - 0.11 12.5 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 HisG, C-terminal domain Transket_pyr PF02779.19 EME88589.1 - 2.3e-49 167.3 0.0 3.7e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME88589.1 - 2.7e-35 121.0 0.2 7.7e-35 119.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain ABA_GPCR PF12430.3 EME88591.1 - 8.1e-54 181.7 0.1 8.1e-54 181.7 0.1 2.1 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EME88591.1 - 1e-20 73.5 0.2 4.3e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) F-box-like PF12937.2 EME88593.1 - 0.00076 19.1 0.4 0.0033 17.1 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EME88593.1 - 0.0055 16.3 0.1 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain RNA_pol_N PF01194.12 EME88593.1 - 0.026 14.5 0.7 0.63 10.1 0.4 2.8 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Herpes_BLLF1 PF05109.8 EME88594.1 - 0.17 9.8 7.8 0.21 9.4 5.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) CFC PF09443.5 EME88596.1 - 0.01 15.4 0.4 0.01 15.4 0.3 2.0 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) BTB PF00651.26 EME88598.1 - 2.8e-06 27.2 0.0 5.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SKG6 PF08693.5 EME88598.1 - 6e-06 25.4 4.8 1.2e-05 24.5 3.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EME88598.1 - 0.0063 16.0 0.2 0.01 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 EME88598.1 - 0.029 12.6 0.0 0.049 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EME88598.1 - 0.032 13.9 0.1 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.6 EME88598.1 - 0.093 12.3 0.4 0.16 11.5 0.3 1.3 1 0 0 1 1 1 0 Protocadherin AJAP1_PANP_C PF15298.1 EME88598.1 - 0.19 11.6 0.1 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TBPIP PF07106.8 EME88599.1 - 0.0048 16.4 10.5 0.024 14.2 0.9 2.7 1 1 1 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EME88599.1 - 0.005 17.1 8.8 0.23 11.8 0.3 3.4 1 1 0 2 2 2 1 Protein of unknown function (DUF972) GAS PF13851.1 EME88599.1 - 0.011 14.9 8.5 0.21 10.7 0.3 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EME88599.1 - 0.016 15.4 10.0 1.2 9.4 1.7 3.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EME88599.1 - 0.021 14.6 1.4 0.021 14.6 1.0 2.9 1 1 0 2 2 2 0 Tropomyosin like Spectrin PF00435.16 EME88599.1 - 0.028 14.6 13.4 1.1 9.5 1.6 3.4 1 1 3 4 4 4 0 Spectrin repeat Baculo_PEP_C PF04513.7 EME88599.1 - 0.044 13.6 12.6 0.39 10.5 1.2 3.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.1 EME88599.1 - 0.089 12.8 15.3 0.37 10.8 1.9 2.6 3 0 0 3 3 2 0 Syntaxin-like protein ALS2CR8 PF15299.1 EME88599.1 - 0.16 11.5 8.0 0.22 11.0 5.6 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 HsbA PF12296.3 EME88599.1 - 0.22 11.3 8.6 0.55 10.0 3.8 2.9 2 1 1 3 3 3 0 Hydrophobic surface binding protein A Prefoldin PF02996.12 EME88599.1 - 0.32 10.6 7.8 10 5.8 0.0 4.2 2 2 3 5 5 5 0 Prefoldin subunit Filament PF00038.16 EME88599.1 - 0.34 10.3 18.4 0.16 11.3 1.0 2.7 1 1 1 3 3 3 0 Intermediate filament protein DivIC PF04977.10 EME88599.1 - 0.4 10.2 9.7 4.7 6.7 1.1 4.2 3 2 2 5 5 5 0 Septum formation initiator Prominin PF05478.6 EME88599.1 - 0.45 7.9 12.6 0.08 10.4 0.7 2.5 1 1 2 3 3 3 0 Prominin IncA PF04156.9 EME88599.1 - 0.47 10.0 11.9 0.72 9.4 1.5 3.1 2 1 0 2 2 2 0 IncA protein M_domain PF12938.2 EME88599.1 - 0.85 9.3 5.5 53 3.5 3.8 2.7 1 1 0 1 1 1 0 M domain of GW182 DUF724 PF05266.9 EME88599.1 - 0.89 9.1 11.4 2.5 7.6 1.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 EME88599.1 - 1 9.4 8.6 4 7.4 2.3 2.8 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HisKA_3 PF07730.8 EME88599.1 - 1.3 9.4 11.5 3.8 7.9 0.2 3.8 3 2 1 4 4 4 0 Histidine kinase DUF1664 PF07889.7 EME88599.1 - 1.3 8.8 14.8 9.1 6.1 0.5 4.2 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) APG6 PF04111.7 EME88599.1 - 2 7.3 13.8 2.1 7.2 2.5 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 STAT_alpha PF01017.15 EME88599.1 - 2.4 7.8 19.0 0.28 10.8 3.2 2.7 1 1 1 2 2 2 0 STAT protein, all-alpha domain Fib_alpha PF08702.5 EME88599.1 - 3.3 7.8 15.8 1.8 8.7 2.5 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ACCA PF03255.9 EME88599.1 - 3.8 7.0 9.1 4.5 6.8 0.2 3.2 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit KLRAQ PF10205.4 EME88599.1 - 4.8 7.2 9.6 0.94 9.5 1.9 2.5 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein Syntaxin-6_N PF09177.6 EME88599.1 - 8 6.9 15.6 2.5 8.5 2.0 3.5 2 2 2 4 4 4 0 Syntaxin 6, N-terminal AIP3 PF03915.8 EME88599.1 - 9.4 5.0 17.1 24 3.6 11.9 1.7 1 1 0 1 1 1 0 Actin interacting protein 3 Aldolase_II PF00596.16 EME88600.1 - 1.4e-47 161.6 0.1 1.7e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lactamase_B PF00753.22 EME88601.1 - 8.9e-06 25.4 4.5 4.7e-05 23.1 3.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EME88601.1 - 0.0015 18.0 0.2 0.0036 16.8 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HlyIII PF03006.15 EME88602.1 - 1.2 8.5 11.4 1.8 7.9 7.2 2.0 1 1 0 1 1 1 0 Haemolysin-III related Methyltransf_23 PF13489.1 EME88603.1 - 3e-20 72.5 0.0 4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME88603.1 - 1.2e-16 60.6 0.0 4.3e-16 58.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME88603.1 - 1.3e-15 57.6 0.0 2.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME88603.1 - 8.7e-15 55.2 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME88603.1 - 4.5e-14 52.7 0.0 9.3e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EME88603.1 - 1.5e-09 37.3 0.0 6.4e-09 35.2 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EME88603.1 - 4.8e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EME88603.1 - 2.8e-05 23.5 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EME88603.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EME88603.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EME88603.1 - 0.00036 20.1 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EME88603.1 - 0.00046 19.3 0.0 0.00067 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EME88603.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EME88603.1 - 0.01 16.6 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EME88603.1 - 0.022 14.0 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 EME88603.1 - 0.042 13.8 0.6 0.27 11.2 0.1 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EME88603.1 - 0.071 12.1 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.7 EME88603.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NodS PF05401.6 EME88603.1 - 0.14 11.5 0.0 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) BTB PF00651.26 EME88605.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Homoserine_dh PF00742.14 EME88606.1 - 1.1e-50 171.7 0.0 1.5e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EME88606.1 - 3.5e-14 53.2 0.0 5.9e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Cys_Met_Meta_PP PF01053.15 EME88606.1 - 0.1 10.8 0.0 2.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF4078 PF13300.1 EME88607.1 - 1.8e-28 98.4 12.9 1.8e-28 98.4 8.9 3.2 2 1 0 3 3 3 1 Domain of unknown function (DUF4078) CAF1A PF12253.3 EME88607.1 - 0.4 10.8 6.2 1.9 8.6 4.3 2.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A F-box-like PF12937.2 EME88609.1 - 1.3e-05 24.7 0.1 3.1e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME88609.1 - 2.5e-05 23.7 0.0 5.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Glyco_hydro_43 PF04616.9 EME88611.1 - 6.9e-37 127.0 3.6 7.8e-37 126.8 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 WYL PF13280.1 EME88611.1 - 0.078 12.8 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 WYL domain Actin PF00022.14 EME88612.1 - 1.1e-54 185.4 0.0 2.9e-29 101.6 0.0 2.2 2 0 0 2 2 2 2 Actin SapB_1 PF05184.10 EME88612.1 - 2.2 8.2 4.6 0.72 9.7 0.6 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 F-box PF00646.28 EME88615.1 - 0.00049 19.6 3.0 0.00064 19.3 0.5 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EME88615.1 - 0.015 15.0 0.4 0.015 15.0 0.3 2.2 2 0 0 2 2 2 0 F-box-like Fibrinogen_BP PF08017.6 EME88617.1 - 0.032 12.4 1.3 0.046 11.9 0.9 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein Cas_Csx9 PF09658.5 EME88617.1 - 0.072 11.8 0.2 0.17 10.6 0.1 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csx9) Peptidase_S9 PF00326.16 EME88618.1 - 1.4e-46 158.4 0.9 2e-46 157.9 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME88618.1 - 4.3e-08 33.0 0.0 1.3e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME88618.1 - 0.00016 21.6 0.3 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EME88618.1 - 0.00097 18.7 5.8 0.25 11.0 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat MARVEL PF01284.18 EME88619.1 - 0.00067 19.4 3.9 0.0015 18.3 2.7 1.5 1 1 0 1 1 1 1 Membrane-associating domain UCR_UQCRX_QCR9 PF05365.7 EME88619.1 - 0.45 10.1 3.5 1.1 8.9 2.4 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-RING_2 PF13639.1 EME88620.1 - 5.8e-08 32.4 12.6 1.1e-07 31.5 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME88620.1 - 0.0014 18.1 11.2 0.0025 17.4 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME88620.1 - 0.0022 17.9 13.8 0.0041 17.1 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME88620.1 - 0.0052 16.4 10.0 0.0091 15.6 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME88620.1 - 0.0059 16.6 6.8 0.016 15.2 4.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EME88620.1 - 0.14 11.9 11.2 0.27 10.9 7.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME88620.1 - 0.4 10.4 9.2 0.94 9.2 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TPR_16 PF13432.1 EME88621.1 - 3.2e-11 43.5 3.0 0.00043 20.8 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EME88621.1 - 6e-09 36.1 3.8 0.00015 22.0 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EME88621.1 - 3.4e-06 27.1 0.5 0.094 13.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME88621.1 - 1.2e-05 25.4 10.2 2.1 9.2 0.1 5.6 2 1 4 6 6 6 3 Tetratricopeptide repeat BTAD PF03704.12 EME88621.1 - 0.00018 21.8 5.0 0.00061 20.1 0.1 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_2 PF07719.12 EME88621.1 - 0.0008 19.1 0.2 4.6 7.4 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME88621.1 - 0.0071 15.9 3.8 5.2 6.7 0.0 4.2 2 1 2 4 4 4 2 TPR repeat PerC PF06069.6 EME88621.1 - 0.052 13.5 0.0 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 PerC transcriptional activator TPR_21 PF09976.4 EME88621.1 - 0.24 11.3 3.9 0.089 12.7 0.5 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.13 EME88622.1 - 4.5e-57 192.2 0.1 9.3e-57 191.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME88622.1 - 3e-44 150.2 0.1 5.4e-43 146.2 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME88622.1 - 1.9e-37 128.0 0.4 7e-37 126.2 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Med3 PF11593.3 EME88622.1 - 0.0082 15.4 3.0 0.012 14.9 2.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal POR_N PF01855.14 EME88622.1 - 0.0086 15.6 0.7 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Retinal PF15449.1 EME88622.1 - 4.9 4.6 18.4 6.8 4.2 12.8 1.1 1 0 0 1 1 1 0 Retinal protein DUF3724 PF12521.3 EME88623.1 - 0.071 12.8 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Pectinesterase PF01095.14 EME88624.1 - 6.5e-11 41.3 0.0 7.3e-11 41.1 0.0 1.1 1 0 0 1 1 1 1 Pectinesterase CRC_subunit PF08624.5 EME88626.1 - 9.2e-57 190.8 0.2 1.5e-56 190.2 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF2890 PF11081.3 EME88626.1 - 3.3 7.7 5.4 5.9 6.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Cyclin PF08613.6 EME88628.1 - 1.7e-14 54.4 0.1 3.2e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EME88628.1 - 4.8e-05 22.9 0.1 9.2e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.20 EME88630.1 - 1.7e-12 47.5 0.3 1.1e-11 44.9 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME88630.1 - 0.039 13.6 0.1 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 KR domain Peptidase_C12 PF01088.16 EME88631.1 - 2.2e-51 174.1 0.0 2.7e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_18 PF00704.23 EME88632.1 - 1.8e-15 57.2 3.5 2.7e-14 53.4 0.9 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Pkinase PF00069.20 EME88633.1 - 8.4e-70 234.8 0.0 1.2e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME88633.1 - 1.7e-30 106.0 0.0 2.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EME88633.1 - 6.2e-13 49.0 1.5 3e-12 46.8 1.0 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EME88633.1 - 2.4e-08 33.3 0.0 4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EME88633.1 - 0.00062 19.5 0.4 0.0049 16.6 0.3 2.3 1 1 0 1 1 1 1 C2 domain APH PF01636.18 EME88633.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME88633.1 - 0.047 13.2 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EME88633.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EME88633.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MaoC_dehydratas PF01575.14 EME88634.1 - 1.5e-22 79.2 0.0 2.5e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EME88634.1 - 2e-11 43.7 0.0 4.7e-09 36.1 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase ABC_tran PF00005.22 EME88635.1 - 2.8e-34 118.3 0.0 6.7e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EME88635.1 - 4.6e-17 62.3 6.1 9.6e-17 61.2 4.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EME88635.1 - 0.00015 21.8 0.0 0.069 13.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EME88635.1 - 0.00022 20.5 0.0 0.0018 17.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EME88635.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EME88635.1 - 0.003 16.6 0.0 0.0071 15.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EME88635.1 - 0.0068 15.9 1.4 0.018 14.5 0.1 2.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EME88635.1 - 0.011 15.7 0.2 0.052 13.5 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.1 EME88635.1 - 0.033 14.1 0.2 0.24 11.3 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EME88635.1 - 0.055 14.2 0.2 0.58 10.9 0.1 2.7 3 1 0 3 3 2 0 AAA domain AAA_22 PF13401.1 EME88635.1 - 0.079 13.0 0.1 0.35 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EME88635.1 - 0.086 13.1 0.2 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EME88635.1 - 0.096 12.1 0.3 0.96 8.8 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain Glyco_tranf_2_3 PF13641.1 EME88637.1 - 1.4e-15 57.7 0.1 2.2e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EME88637.1 - 3.7e-08 32.8 0.0 4.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EME88637.1 - 1.9e-06 27.6 0.1 3.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 GalKase_gal_bdg PF10509.4 EME88639.1 - 1.5e-19 69.0 0.0 2.8e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EME88639.1 - 4.2e-15 55.5 0.8 2.1e-14 53.3 0.8 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EME88639.1 - 9.2e-15 54.6 0.0 4.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal DUF1983 PF09327.6 EME88639.1 - 0.03 14.2 0.8 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) Seipin PF06775.9 EME88640.1 - 1.2e-50 171.8 0.3 1.5e-50 171.4 0.2 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) QCR10 PF09796.4 EME88640.1 - 2.2 7.9 5.3 7.5 6.2 0.2 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RabGAP-TBC PF00566.13 EME88641.1 - 1.8e-34 119.0 0.0 4e-34 117.9 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain UQ_con PF00179.21 EME88642.1 - 6.4e-40 135.8 0.1 7.2e-40 135.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME88642.1 - 7.6e-06 25.8 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EME88642.1 - 8.1e-06 25.6 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EME88642.1 - 0.0071 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain BTB PF00651.26 EME88643.1 - 1.8e-07 31.1 0.0 6.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Vps35 PF03635.12 EME88645.1 - 7.6e-286 950.2 1.6 1e-182 609.2 0.6 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 35 FAD_binding_3 PF01494.14 EME88646.1 - 8.3e-22 77.7 0.3 1e-14 54.3 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 EME88646.1 - 4.7e-12 45.4 2.8 2.6e-05 23.3 1.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME88646.1 - 6e-07 29.3 0.1 1.6e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME88646.1 - 7.3e-07 28.3 3.2 7.4e-05 21.7 1.4 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EME88646.1 - 7.8e-07 29.1 0.9 1.3e-05 25.1 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME88646.1 - 5.2e-06 25.1 0.2 0.0012 17.3 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EME88646.1 - 6.8e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME88646.1 - 9.7e-05 22.5 0.0 0.00019 21.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME88646.1 - 0.00027 19.9 0.8 0.069 12.0 0.8 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 EME88646.1 - 0.00032 21.0 0.2 0.026 14.9 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME88646.1 - 0.0015 17.6 0.7 0.031 13.3 0.4 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EME88646.1 - 0.0034 17.1 0.3 0.018 14.8 0.2 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EME88646.1 - 0.018 14.6 0.5 0.032 13.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EME88646.1 - 0.091 11.6 0.8 5.8 5.7 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EME88646.1 - 2.6 6.5 5.7 1.1 7.8 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase Plasmod_Pvs28 PF06247.6 EME88648.1 - 0.021 14.4 0.2 0.046 13.2 0.1 1.6 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 Glyco_hydro_43 PF04616.9 EME88650.1 - 4.2e-29 101.5 0.7 6e-29 101.0 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 TauD PF02668.11 EME88651.1 - 6.3e-41 140.7 0.0 7.1e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EME88651.1 - 0.0033 17.8 0.3 0.32 11.5 0.0 2.3 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 EME88651.1 - 0.0039 16.1 0.2 0.074 11.9 0.0 2.1 2 0 0 2 2 2 1 CsiD Glyco_hydro_47 PF01532.15 EME88652.1 - 1.3e-129 432.8 0.0 1.5e-129 432.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 EME88653.1 - 3.9e-65 219.5 0.0 4.6e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME88653.1 - 2.3e-29 102.2 0.0 3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME88653.1 - 0.0029 16.6 0.0 0.0096 14.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EME88653.1 - 0.098 13.1 1.4 0.19 12.2 1.0 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 EME88653.1 - 0.11 12.1 0.7 0.86 9.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HMG_box PF00505.14 EME88655.1 - 4.4e-26 90.9 2.5 6.1e-26 90.4 1.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EME88655.1 - 1.3e-19 70.3 2.8 1.8e-19 69.8 1.9 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EME88655.1 - 0.00025 20.7 0.8 0.00064 19.4 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EME88655.1 - 0.16 12.1 1.8 0.27 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) NRDE PF05742.7 EME88656.1 - 5.8e-52 176.6 0.0 6.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 NRDE protein TB2_DP1_HVA22 PF03134.14 EME88657.1 - 9.2e-24 83.0 3.5 1.3e-23 82.5 2.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF221 PF02714.10 EME88659.1 - 3.2e-85 285.8 20.0 5.4e-85 285.1 13.8 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EME88659.1 - 1.9e-41 141.2 1.2 4.9e-41 139.9 0.8 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EME88659.1 - 5.6e-18 65.2 1.1 1.4e-17 64.0 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) TP2 PF01254.13 EME88659.1 - 0.11 12.8 4.8 0.24 11.7 3.4 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 TMF_TATA_bd PF12325.3 EME88659.1 - 0.24 11.1 0.2 0.77 9.5 0.1 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sugar_tr PF00083.19 EME88661.1 - 7.7e-91 304.9 29.0 8.8e-91 304.7 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88661.1 - 5e-29 101.1 29.4 5e-29 101.1 20.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EME88661.1 - 5e-06 25.0 2.1 5e-06 25.0 1.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UPF0060 PF02694.10 EME88661.1 - 0.0059 16.6 1.6 0.023 14.7 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised BCR, YnfA/UPF0060 family MIP PF00230.15 EME88662.1 - 2.3e-42 144.9 4.7 3.6e-42 144.3 3.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein Ricin_B_lectin PF00652.17 EME88663.1 - 0.0062 16.5 0.4 0.011 15.7 0.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Adeno_PIX PF03955.9 EME88663.1 - 4.7 7.7 10.0 3.4 8.2 1.6 2.7 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) TFR_dimer PF04253.10 EME88666.1 - 8.1e-24 83.5 0.0 1.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EME88666.1 - 1.3e-16 60.8 0.0 3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EME88666.1 - 0.00036 20.1 0.0 0.0009 18.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M9_N PF08453.5 EME88666.1 - 0.096 12.0 0.1 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M9 N-terminal Esterase PF00756.15 EME88667.1 - 9.1e-06 25.2 0.0 4.3e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EME88667.1 - 0.0011 18.2 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_6 PF13344.1 EME88668.1 - 3e-22 78.3 0.0 6.8e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME88668.1 - 9.7e-18 63.6 0.0 3.4e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EME88668.1 - 0.00055 20.2 0.1 0.14 12.3 0.0 2.7 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EME88668.1 - 0.0056 17.1 0.0 0.31 11.4 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EME88668.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Aldo_ket_red PF00248.16 EME88669.1 - 8.5e-57 192.1 0.0 9.8e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_q6 PF01058.17 EME88672.1 - 2e-05 24.1 0.3 2.6e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Glycos_transf_2 PF00535.21 EME88673.1 - 1.5e-32 112.5 0.0 1.8e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EME88673.1 - 2.8e-12 46.9 0.0 6.6e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EME88673.1 - 4.7e-07 29.1 0.0 6.3e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EME88673.1 - 3.9e-05 22.9 0.0 7.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Yip1 PF04893.12 EME88676.1 - 1e-05 25.1 17.3 8.4e-05 22.1 12.0 2.3 1 1 0 1 1 1 1 Yip1 domain Oxidored_q3 PF00499.15 EME88676.1 - 0.38 10.5 8.1 0.77 9.5 5.6 1.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Nup_retrotrp_bd PF10599.4 EME88676.1 - 2.9 8.5 15.0 0.41 11.3 7.5 1.6 2 0 0 2 2 2 0 Retro-transposon transporting motif BTB PF00651.26 EME88678.1 - 0.067 13.1 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain BBP1_N PF15271.1 EME88680.1 - 0.064 13.6 0.0 0.076 13.3 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Pkinase PF00069.20 EME88681.1 - 9.5e-20 70.8 0.0 1.9e-19 69.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME88681.1 - 1e-16 60.7 0.0 1.8e-16 59.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME88681.1 - 3.1e-06 27.1 0.2 4.7e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EME88681.1 - 0.0002 20.4 0.0 0.00039 19.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EME88681.1 - 0.0067 15.5 0.1 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EME88681.1 - 0.034 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EME88681.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.24 EME88684.1 - 1.7e-57 193.2 0.0 1.1e-40 138.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME88684.1 - 7.9e-11 42.2 0.1 0.00044 20.2 0.0 4.0 3 2 2 5 5 4 2 AAA ATPase domain AAA_17 PF13207.1 EME88684.1 - 4.6e-08 33.9 0.0 0.00049 20.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EME88684.1 - 6.3e-07 29.4 0.0 0.014 15.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EME88684.1 - 7.3e-07 29.3 0.3 0.2 11.7 0.0 3.7 2 2 2 4 4 4 2 AAA domain AAA_19 PF13245.1 EME88684.1 - 1.9e-06 27.5 0.0 0.11 12.2 0.0 3.0 2 1 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 EME88684.1 - 5.1e-06 26.4 0.0 0.064 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EME88684.1 - 9.7e-06 25.3 0.1 0.003 17.2 0.0 3.2 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EME88684.1 - 0.00021 21.2 0.0 0.078 12.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EME88684.1 - 0.0004 20.7 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EME88684.1 - 0.0005 19.8 0.6 0.77 9.4 0.0 3.6 2 2 2 4 4 4 1 Archaeal ATPase RNA_helicase PF00910.17 EME88684.1 - 0.00051 20.1 0.0 0.35 11.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EME88684.1 - 0.00055 19.3 0.8 0.37 10.1 0.0 3.6 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.1 EME88684.1 - 0.00072 19.8 0.1 0.036 14.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 EME88684.1 - 0.00083 18.3 0.0 0.049 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EME88684.1 - 0.0017 17.1 0.0 0.02 13.5 0.0 2.5 3 0 0 3 3 3 1 TIP49 C-terminus NACHT PF05729.7 EME88684.1 - 0.002 17.7 0.0 0.15 11.7 0.0 3.3 3 1 1 4 4 3 1 NACHT domain DUF258 PF03193.11 EME88684.1 - 0.0032 16.6 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 CDC48_N PF02359.13 EME88684.1 - 0.0041 17.0 0.0 0.018 14.9 0.0 2.1 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.21 EME88684.1 - 0.0041 16.5 0.0 0.99 8.8 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.1 EME88684.1 - 0.005 16.3 0.0 0.023 14.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EME88684.1 - 0.0079 16.4 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EME88684.1 - 0.0091 16.0 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EME88684.1 - 0.013 14.9 0.0 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 EME88684.1 - 0.014 15.2 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EME88684.1 - 0.019 14.0 0.0 0.39 9.7 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EME88684.1 - 0.023 14.6 0.1 0.085 12.8 0.0 2.0 1 1 1 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 EME88684.1 - 0.037 12.9 0.0 0.087 11.7 0.0 1.6 2 0 0 2 2 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EME88684.1 - 0.047 12.7 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_3 PF07726.6 EME88684.1 - 0.068 12.7 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EME88684.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.4 EME88684.1 - 0.081 11.8 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 EME88684.1 - 0.092 12.3 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4191 PF13829.1 EME88684.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Bac_DnaA PF00308.13 EME88684.1 - 0.11 12.1 0.0 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_24 PF13479.1 EME88684.1 - 0.11 12.0 0.0 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EME88684.1 - 0.17 11.0 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.13 EME88684.1 - 0.17 11.3 0.0 0.8 9.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EME88684.1 - 0.21 10.4 0.0 18 4.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EME88684.1 - 0.22 10.1 0.1 3.6 6.1 0.0 2.4 2 1 1 3 3 3 0 Rad17 cell cycle checkpoint protein NCA2 PF08637.5 EME88685.1 - 2e-84 282.9 0.1 3.4e-84 282.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.17 EME88687.1 - 1.3e-65 219.6 0.1 1.6e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME88687.1 - 1.3e-19 70.8 0.0 2.2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EME88687.1 - 3.4e-13 49.1 0.0 4.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EME88687.1 - 2.4e-06 27.1 0.1 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EME88687.1 - 5.3e-06 25.7 0.0 6.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EME88687.1 - 0.0045 16.9 0.0 0.0068 16.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EME88687.1 - 0.021 14.0 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EME88687.1 - 0.038 13.2 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EME88687.1 - 0.04 14.1 0.0 5.2 7.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EME88687.1 - 0.063 12.4 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EME88687.1 - 0.072 12.6 0.3 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EME88687.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain UCH PF00443.24 EME88688.1 - 3.4e-43 147.6 0.0 1e-36 126.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME88688.1 - 6.8e-14 51.9 0.1 7.8e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L9_C PF03948.9 EME88689.1 - 0.0004 20.4 0.3 0.5 10.4 0.0 2.5 1 1 1 2 2 2 2 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.14 EME88689.1 - 0.023 13.9 0.0 0.07 12.3 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L9, N-terminal domain Glyco_hyd_65N_2 PF14498.1 EME88690.1 - 3.9e-40 137.9 0.0 6.4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sugar_tr PF00083.19 EME88691.1 - 3.7e-75 253.2 17.9 4.2e-75 253.0 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88691.1 - 3e-11 42.6 35.5 1.9e-09 36.7 19.1 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EME88692.1 - 1.3e-17 64.5 0.2 1.5e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME88692.1 - 3.2e-10 39.9 0.0 8.8e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME88692.1 - 4.6e-10 39.4 0.0 1.3e-09 37.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EME88692.1 - 0.00041 20.1 0.0 0.035 13.8 0.0 2.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 EME88692.1 - 0.003 17.1 0.0 0.0053 16.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EME88692.1 - 0.015 15.1 0.0 0.067 13.0 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Cyclin_N PF00134.18 EME88693.1 - 2.6e-15 56.0 0.2 9.1e-14 51.1 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EME88693.1 - 0.84 9.4 3.0 18 5.1 0.2 2.3 2 0 0 2 2 2 0 Transcription factor TFIIB repeat TMA7 PF09072.5 EME88694.1 - 1.4e-05 25.4 14.6 1.4e-05 25.4 10.1 1.8 2 0 0 2 2 2 1 Translation machinery associated TMA7 Sugar_tr PF00083.19 EME88697.1 - 2.3e-130 435.1 29.2 2.6e-130 435.0 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88697.1 - 9.8e-24 83.7 48.3 3.4e-20 72.0 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ndc80_HEC PF03801.8 EME88699.1 - 2e-54 183.3 0.1 4e-54 182.3 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family MukB PF04310.7 EME88699.1 - 0.036 13.3 0.0 0.093 12.0 0.0 1.6 1 0 0 1 1 1 0 MukB N-terminal Filament PF00038.16 EME88699.1 - 0.17 11.3 54.6 0.042 13.3 12.8 4.0 2 2 2 4 4 4 0 Intermediate filament protein Reo_sigmaC PF04582.7 EME88699.1 - 0.4 9.7 5.6 1.7 7.7 1.0 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein WASH_WAHD PF11945.3 EME88699.1 - 0.91 8.7 12.0 0.056 12.7 2.6 2.7 2 2 0 2 2 2 0 WAHD domain of WASH complex NPV_P10 PF05531.7 EME88699.1 - 4.9 7.4 12.1 8.6 6.6 0.9 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EME88699.1 - 9.2 5.4 57.3 3.6 6.7 9.0 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Pex14_N PF04695.8 EME88701.1 - 3.1e-25 88.7 3.1 3.1e-25 88.7 2.1 3.3 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GrpE PF01025.14 EME88701.1 - 0.0036 16.8 5.5 0.0074 15.8 3.8 1.5 1 0 0 1 1 1 1 GrpE IncA PF04156.9 EME88701.1 - 0.0066 16.0 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 IncA protein DUF4235 PF14019.1 EME88701.1 - 0.018 14.9 0.7 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Myosin_tail_1 PF01576.14 EME88701.1 - 0.073 10.7 12.2 0.098 10.3 8.5 1.1 1 0 0 1 1 1 0 Myosin tail ERM PF00769.14 EME88701.1 - 0.084 12.3 14.7 0.15 11.6 10.2 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 EME88701.1 - 0.28 11.0 2.3 0.39 10.5 0.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 EME88701.1 - 0.38 8.0 8.5 0.55 7.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pex16 PF08610.5 EME88701.1 - 7.5 5.4 9.4 2 7.3 1.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) F-box-like PF12937.2 EME88703.1 - 6.6e-06 25.7 0.1 1.6e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME88703.1 - 7e-06 25.5 0.4 1.7e-05 24.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain COX16 PF14138.1 EME88706.1 - 2.4e-32 110.9 0.1 3e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 PI3_PI4_kinase PF00454.22 EME88707.1 - 2.4e-52 177.7 0.0 4.4e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EME88707.1 - 9.2e-33 113.6 3.2 2e-32 112.5 2.2 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EME88707.1 - 3.5e-25 88.0 0.0 2.2e-24 85.4 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EME88707.1 - 1.4e-10 40.4 0.0 3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 EME88707.1 - 0.074 12.9 0.1 0.58 10.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) MAT_Alpha1 PF04769.7 EME88707.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 TPR_16 PF13432.1 EME88707.1 - 0.68 10.6 8.4 12 6.6 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat MS_channel PF00924.13 EME88708.1 - 5.4e-17 61.8 1.5 1e-16 60.8 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EME88708.1 - 0.0031 16.6 0.1 0.008 15.4 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EME88708.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EME88708.1 - 0.063 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair ABC_tran PF00005.22 EME88709.1 - 3.3e-43 147.2 0.0 4.3e-21 75.6 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME88709.1 - 3e-14 53.6 0.1 0.0065 16.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EME88709.1 - 1.1e-11 44.4 0.2 0.0017 17.6 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EME88709.1 - 1.5e-08 34.0 0.0 0.0016 17.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EME88709.1 - 1.9e-06 28.6 2.3 0.04 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EME88709.1 - 2.4e-06 28.0 0.6 0.026 14.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EME88709.1 - 5.7e-06 26.0 1.0 0.012 15.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain DUF258 PF03193.11 EME88709.1 - 5.7e-06 25.6 0.1 0.0027 16.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_tran_2 PF12848.2 EME88709.1 - 1e-05 25.2 7.1 1e-05 25.2 4.9 2.2 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EME88709.1 - 0.00053 20.1 0.2 0.39 10.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EME88709.1 - 0.00067 19.6 7.3 0.0088 16.0 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EME88709.1 - 0.0011 19.4 0.4 2.1 8.8 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein NB-ARC PF00931.17 EME88709.1 - 0.0016 17.3 0.2 0.53 9.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 EME88709.1 - 0.0042 17.2 0.0 3.4 7.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EME88709.1 - 0.0081 16.1 0.1 5.2 7.0 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EME88709.1 - 0.0095 15.8 5.7 0.29 11.0 0.0 3.6 3 1 0 3 3 3 1 AAA domain ArgK PF03308.11 EME88709.1 - 0.013 14.3 2.4 0.86 8.3 0.1 3.0 3 0 0 3 3 3 0 ArgK protein NTPase_1 PF03266.10 EME88709.1 - 0.013 15.1 1.0 2.2 7.9 0.1 3.2 3 1 0 3 3 3 0 NTPase DUF815 PF05673.8 EME88709.1 - 0.021 13.7 0.1 0.91 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EME88709.1 - 0.022 14.1 0.1 4.9 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain DAP3 PF10236.4 EME88709.1 - 0.023 13.6 0.6 0.39 9.5 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SbcCD_C PF13558.1 EME88709.1 - 0.046 13.6 0.0 4.5 7.2 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EME88709.1 - 0.091 12.9 1.4 1.7 8.8 0.0 2.7 3 0 0 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EME88709.1 - 0.097 12.1 5.6 2.5 7.5 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EME88709.1 - 0.1 12.0 3.8 1.8 7.8 0.4 2.7 3 0 0 3 3 3 0 AAA-like domain G-alpha PF00503.15 EME88709.1 - 0.19 10.3 1.4 4.6 5.8 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit AAA_13 PF13166.1 EME88709.1 - 0.23 9.8 2.5 21 3.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EME88709.1 - 0.43 10.8 4.7 16 5.8 0.8 3.2 2 1 0 2 2 2 0 AAA domain Snf7 PF03357.16 EME88710.1 - 3.2e-21 75.4 13.5 3.8e-21 75.2 9.3 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EME88710.1 - 0.0022 17.4 3.8 0.004 16.5 2.6 1.3 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GrpE PF01025.14 EME88710.1 - 0.15 11.6 5.9 0.32 10.5 4.1 1.5 1 0 0 1 1 1 0 GrpE DUF3573 PF12097.3 EME88710.1 - 0.22 10.1 3.5 0.26 9.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) XhlA PF10779.4 EME88710.1 - 1.2 9.1 5.8 2.6 8.0 3.8 1.9 1 1 0 1 1 1 0 Haemolysin XhlA Vps51 PF08700.6 EME88710.1 - 3.5 7.5 9.1 1.8 8.4 3.6 2.4 2 1 1 3 3 3 0 Vps51/Vps67 DltD_M PF04918.7 EME88710.1 - 4.7 7.3 9.1 7.3 6.7 5.6 1.7 1 1 1 2 2 2 0 DltD central region Nic96 PF04097.9 EME88711.1 - 7.2e-185 615.6 1.3 9.2e-185 615.3 0.9 1.1 1 0 0 1 1 1 1 Nup93/Nic96 YL1_C PF08265.6 EME88712.1 - 2.6e-17 62.0 2.4 4.2e-17 61.3 1.7 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain BNIP3 PF06553.7 EME88712.1 - 0.098 12.0 0.6 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 BNIP3 Longin PF13774.1 EME88713.1 - 2.3e-18 65.5 0.1 3.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EME88713.1 - 2e-14 52.9 0.3 4.1e-14 51.9 0.2 1.5 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EME88713.1 - 0.052 13.3 0.3 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 p450 PF00067.17 EME88714.1 - 1.6e-64 218.1 0.0 2.4e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EME88716.1 - 0.00062 19.4 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME88716.1 - 0.00083 18.9 0.0 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain PAP_assoc PF03828.14 EME88717.1 - 6.3e-20 70.8 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EME88717.1 - 0.00029 21.0 0.0 0.00068 19.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.7 EME88718.1 - 5.1 5.3 65.9 0.32 9.3 8.0 3.8 1 1 2 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AA_permease_2 PF13520.1 EME88719.1 - 1.9e-83 280.3 34.5 2.4e-83 280.0 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EME88720.1 - 0.36 9.4 4.0 1 7.9 2.7 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily F-box-like PF12937.2 EME88721.1 - 0.0096 15.6 0.5 0.15 11.7 0.2 3.0 3 0 0 3 3 3 1 F-box-like Methyltransf_31 PF13847.1 EME88722.1 - 4.7e-10 39.2 0.0 9.2e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EME88722.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EME88722.1 - 2.7e-08 34.3 0.0 9.7e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME88722.1 - 4.8e-08 33.0 0.0 2.2e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME88722.1 - 4.2e-07 30.3 0.0 1.2e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EME88722.1 - 3.9e-06 25.8 0.1 5.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EME88722.1 - 1e-05 24.7 0.0 2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 EME88722.1 - 0.00013 22.3 0.0 0.00043 20.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EME88722.1 - 0.00017 20.8 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EME88722.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME88722.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EME88722.1 - 0.0024 18.2 0.0 0.0057 17.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME88722.1 - 0.036 13.7 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EME88723.1 - 3.1e-32 111.6 28.6 1.6e-30 106.0 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME88723.1 - 2.5e-11 42.8 5.3 2.5e-11 42.8 3.7 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EME88723.1 - 0.0024 16.1 0.6 0.0036 15.5 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EME88723.1 - 0.02 13.0 2.1 0.037 12.1 1.5 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector Folate_carrier PF01770.13 EME88723.1 - 0.075 11.5 1.8 0.17 10.3 0.1 2.1 2 0 0 2 2 2 0 Reduced folate carrier Arginosuc_synth PF00764.14 EME88724.1 - 3e-156 520.3 0.0 3.4e-156 520.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EME88724.1 - 0.00019 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EME88724.1 - 0.026 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EME88724.1 - 0.051 12.1 0.0 0.072 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Oxidored_FMN PF00724.15 EME88727.1 - 5.7e-96 321.4 0.0 6.6e-96 321.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UNC119_bdg PF15435.1 EME88729.1 - 0.16 11.3 0.4 0.16 11.2 0.3 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue DOT1 PF08123.8 EME88730.1 - 2.9e-40 137.7 0.0 3.9e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EME88730.1 - 7.2e-08 33.0 0.0 4.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME88730.1 - 2e-06 27.7 0.0 5.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME88730.1 - 0.0026 17.3 0.0 0.0048 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME88730.1 - 0.0072 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME88730.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.8 EME88731.1 - 7.4e-46 156.3 0.0 1e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EME88731.1 - 1.3e-10 40.6 0.1 3e-10 39.4 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EME88731.1 - 1.5e-05 24.8 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EME88731.1 - 0.031 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2424 PF10340.4 EME88731.1 - 0.045 12.3 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF2974 PF11187.3 EME88731.1 - 0.07 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 EME88731.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Sugar_tr PF00083.19 EME88733.1 - 1.2e-121 406.5 24.0 1.3e-121 406.3 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88733.1 - 4e-29 101.4 48.5 2.3e-25 89.0 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ODR4-like PF14778.1 EME88733.1 - 0.041 12.5 0.2 0.087 11.4 0.0 1.5 2 0 0 2 2 2 0 Olfactory receptor 4-like zf-RNPHF PF08080.7 EME88733.1 - 0.16 11.4 2.5 1.5 8.3 0.2 2.9 2 0 0 2 2 2 0 RNPHF zinc finger DUF427 PF04248.7 EME88736.1 - 1.5e-26 91.8 0.1 1.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) ECH PF00378.15 EME88737.1 - 6.2e-49 166.3 0.1 7.9e-49 165.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PVL_ORF50 PF07768.6 EME88737.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family DUF676 PF05057.9 EME88739.1 - 3.5e-39 134.3 0.0 7e-26 90.8 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EME88739.1 - 0.007 15.9 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EME88739.1 - 0.089 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein GMC_oxred_N PF00732.14 EME88740.1 - 2.2e-63 214.1 0.0 2.9e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME88740.1 - 3.2e-28 98.8 0.0 7.2e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EME88740.1 - 0.074 13.0 0.0 0.28 11.2 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain IP_trans PF02121.13 EME88740.1 - 0.079 12.1 0.1 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein Got1 PF04178.7 EME88741.1 - 6.5e-18 64.9 13.5 7.9e-18 64.6 9.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EME88741.1 - 0.081 11.8 4.3 0.095 11.6 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Peptidase_A24 PF01478.13 EME88741.1 - 0.87 9.7 14.6 3.1 8.0 9.4 2.0 1 1 1 2 2 2 0 Type IV leader peptidase family SdpI PF13630.1 EME88741.1 - 4.5 7.0 10.5 8.5 6.1 1.1 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DAHP_synth_1 PF00793.15 EME88742.1 - 5.5e-96 320.4 0.1 6.9e-96 320.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family TFIIB PF00382.14 EME88743.1 - 1e-30 105.3 1.4 1.3e-16 60.1 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EME88743.1 - 9e-17 61.0 0.3 9e-17 61.0 0.2 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EME88743.1 - 0.00038 19.7 1.1 0.0008 18.6 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EME88743.1 - 0.00072 19.1 0.6 0.043 13.3 0.0 2.4 1 1 1 2 2 2 1 Cyclin, N-terminal domain DUF2318 PF10080.4 EME88743.1 - 0.067 12.9 0.3 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-C4pol PF14260.1 EME88744.1 - 0.66 10.0 8.8 0.97 9.4 2.3 2.8 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta BTB PF00651.26 EME88745.1 - 0.0027 17.6 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ComZ PF10815.3 EME88745.1 - 0.019 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 ComZ PPR_2 PF13041.1 EME88746.1 - 3.2e-18 65.4 1.3 3.8e-12 45.9 0.0 5.2 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EME88746.1 - 1e-05 25.4 1.5 1.9 8.9 0.0 5.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EME88746.1 - 0.00021 21.0 1.0 0.0021 17.8 0.0 3.4 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 EME88746.1 - 0.14 11.6 1.0 2.6 7.6 0.0 3.1 2 0 0 2 2 2 0 PPR repeat Kinesin PF00225.18 EME88747.1 - 3.4e-48 164.0 0.0 2.3e-47 161.3 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EME88747.1 - 0.015 15.0 2.2 0.015 15.0 1.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF3456 PF11938.3 EME88747.1 - 0.31 11.0 1.8 0.55 10.2 1.3 1.4 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DEAD PF00270.24 EME88749.1 - 8.3e-46 155.5 0.0 1.4e-44 151.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME88749.1 - 3.7e-28 97.2 0.0 9.3e-28 95.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EME88749.1 - 0.00019 21.3 0.0 0.00068 19.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EME88749.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_19 PF13245.1 EME88749.1 - 0.011 15.4 0.3 0.79 9.5 0.1 3.3 3 0 0 3 3 3 0 Part of AAA domain Desmo_N PF06771.6 EME88749.1 - 0.044 13.7 0.8 2.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Viral Desmoplakin N-terminus AAA_30 PF13604.1 EME88749.1 - 0.09 12.3 0.0 0.43 10.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EME88749.1 - 0.13 11.2 1.8 1 8.3 0.0 2.6 3 1 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF1263 PF06882.7 EME88750.1 - 0.064 12.8 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Alpha-L-AF_C PF06964.7 EME88751.1 - 1.3e-26 93.4 0.0 2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus zf-PARP PF00645.13 EME88753.1 - 4e-21 75.0 0.0 4.9e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Rhabdo_glycop PF00974.13 EME88753.1 - 0.072 11.3 0.1 0.074 11.2 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein ATP_sub_h PF10775.4 EME88754.1 - 1e-25 89.2 2.2 1.9e-25 88.3 1.5 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EME88754.1 - 0.0056 16.5 0.1 0.019 14.8 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 Hormone_3 PF00159.13 EME88754.1 - 3.8 7.6 6.7 0.72 9.9 1.8 1.9 2 0 0 2 2 2 0 Pancreatic hormone peptide TFIIB PF00382.14 EME88755.1 - 6.6e-38 128.3 0.5 7.7e-20 70.4 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EME88755.1 - 1e-12 47.1 0.3 1.7e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EME88755.1 - 0.038 13.9 0.1 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Abhydrolase_3 PF07859.8 EME88757.1 - 9.5e-37 126.6 0.1 1.1e-35 123.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Gp_dh_C PF02800.15 EME88757.1 - 0.00072 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF2424 PF10340.4 EME88757.1 - 0.00088 18.0 0.0 0.0014 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EME88757.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EME88757.1 - 0.091 12.9 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Fungal_trans PF04082.13 EME88759.1 - 7.7e-16 57.7 0.0 1.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Folliculin PF11704.3 EME88759.1 - 0.058 12.9 0.0 8.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF505 PF04458.7 EME88759.1 - 0.1 10.6 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) DUF566 PF04484.7 EME88760.1 - 5 6.5 8.3 8.8 5.7 5.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) ERG2_Sigma1R PF04622.7 EME88761.1 - 1.4e-92 308.8 0.3 1.6e-92 308.6 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein HR1 PF02185.11 EME88763.1 - 0.13 11.9 2.7 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 Hr1 repeat cwf21 PF08312.7 EME88763.1 - 0.23 11.3 10.2 0.22 11.4 3.3 2.4 2 1 0 2 2 2 0 cwf21 domain HrpJ PF07201.6 EME88763.1 - 0.8 9.6 6.0 2.5 8.0 3.2 1.9 1 1 1 2 2 2 0 HrpJ-like domain DUF1843 PF08898.5 EME88763.1 - 1.7 8.7 4.2 3.1 7.9 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Cyt-b5 PF00173.23 EME88765.1 - 8e-14 51.1 0.0 9.7e-14 50.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ATP_synth_reg PF14960.1 EME88765.1 - 0.13 11.4 0.0 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 ATP synthase regulation Abhydrolase_6 PF12697.2 EME88767.1 - 1.3e-26 93.8 0.0 2.6e-26 92.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME88767.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME88767.1 - 1.1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME88767.1 - 6.8e-05 22.6 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DUF3530 PF12048.3 EME88767.1 - 0.021 13.7 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2305 PF10230.4 EME88767.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1884 PF08967.5 EME88767.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1884) HET PF06985.6 EME88768.1 - 3e-23 82.5 0.0 4.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.17 EME88769.1 - 2.1e-07 30.4 0.0 3.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME88769.1 - 8.7e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME88769.1 - 0.00091 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME88769.1 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EME88770.1 - 8.5e-28 96.1 0.4 1.4e-27 95.3 0.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EME88770.1 - 9.5e-21 74.1 0.0 2.1e-20 72.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME88770.1 - 6.4e-17 61.5 0.0 1.5e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME88770.1 - 5.2e-14 52.2 0.0 8.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME88770.1 - 1.1e-12 48.1 0.0 2.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EME88770.1 - 3.2e-11 42.8 0.0 4.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EME88770.1 - 6.8e-11 41.7 0.0 1.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EME88770.1 - 1.8e-10 41.4 0.0 3.5e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME88770.1 - 1e-09 38.3 0.0 2.8e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME88770.1 - 1.5e-09 38.2 0.0 2.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EME88770.1 - 4.2e-05 22.0 0.0 5.4e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EME88770.1 - 0.00027 20.3 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EME88770.1 - 0.00029 20.0 0.0 0.00057 19.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EME88770.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EME88770.1 - 0.00086 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 EME88770.1 - 0.0056 16.0 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.13 EME88770.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EME88770.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.6 EME88770.1 - 0.038 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.13 EME88770.1 - 0.038 13.1 0.1 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Met_10 PF02475.11 EME88770.1 - 0.045 13.3 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 EME88770.1 - 0.064 14.1 0.0 0.19 12.5 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Pox_MCEL PF03291.11 EME88770.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_3 PF01596.12 EME88770.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Complex1_LYR PF05347.10 EME88771.1 - 3.1e-07 30.0 0.1 5.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME88771.1 - 3.6e-05 23.8 1.0 6e-05 23.1 0.6 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EME88771.1 - 0.0045 17.4 0.3 0.0062 16.9 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 EME88772.1 - 9.1e-11 41.6 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME88772.1 - 1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME88772.1 - 5.1e-09 35.7 0.1 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EME88772.1 - 3.7e-08 33.4 0.1 7.1e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME88772.1 - 7e-08 32.3 0.0 1.4e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME88772.1 - 4.3e-07 29.9 0.0 5.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME88772.1 - 9.7e-07 28.5 0.0 3.3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EME88772.1 - 0.00051 20.2 0.0 0.00063 19.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Toxin_23 PF08093.6 EME88775.1 - 0.15 12.0 4.4 0.42 10.5 3.1 1.8 1 0 0 1 1 1 0 Magi 5 toxic peptide family Toxin_12 PF07740.7 EME88775.1 - 1.1 9.7 6.5 4 8.0 4.5 2.0 1 0 0 1 1 1 0 Ion channel inhibitory toxin p450 PF00067.17 EME88776.1 - 2e-71 240.9 0.0 2.5e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like_2 PF13013.1 EME88777.1 - 0.063 12.9 0.6 0.16 11.7 0.4 1.8 1 1 0 1 1 1 0 F-box-like domain ETF_QO PF05187.8 EME88778.1 - 5.2e-48 161.6 0.1 8.6e-48 160.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EME88778.1 - 6.2e-09 35.2 0.0 0.00012 21.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME88778.1 - 7.3e-07 29.1 0.0 2.3e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME88778.1 - 2.1e-06 26.8 0.0 0.016 14.0 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EME88778.1 - 0.00032 20.6 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME88778.1 - 0.00066 18.8 0.0 0.0064 15.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EME88778.1 - 0.00067 18.2 0.2 0.0011 17.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EME88778.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EME88778.1 - 0.0023 17.9 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME88778.1 - 0.0028 17.4 0.0 0.0079 15.9 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EME88778.1 - 0.004 17.5 0.0 5.3 7.5 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME88778.1 - 0.0062 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 EME88778.1 - 0.012 15.9 1.0 0.038 14.3 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 EME88778.1 - 0.021 13.7 0.2 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EME88778.1 - 0.053 12.1 0.0 0.13 10.8 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EME88778.1 - 0.22 10.3 0.1 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.17 EME88780.1 - 4.7e-25 87.0 0.0 6.8e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME88780.1 - 7.7e-21 73.8 0.0 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME88780.1 - 7.9e-13 48.0 0.0 1.1e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TBP PF00352.16 EME88782.1 - 1.1e-69 229.7 0.1 1.1e-34 117.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EME88782.1 - 6.1e-05 23.0 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EME88782.1 - 0.076 13.3 0.7 0.1 12.9 0.5 1.4 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Pex24p PF06398.6 EME88783.1 - 3.6e-82 276.0 3.1 5.3e-82 275.4 2.2 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin NUDIX PF00293.23 EME88783.1 - 1.3e-06 28.1 0.5 1e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 NUDIX domain Arylsulfotran_2 PF14269.1 EME88784.1 - 2.6e-46 158.1 0.1 3.8e-46 157.6 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EME88784.1 - 1e-20 73.7 0.0 3.4e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Epimerase PF01370.16 EME88785.1 - 1.6e-16 60.4 0.0 2.9e-16 59.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME88785.1 - 1.3e-09 37.1 0.0 1.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EME88785.1 - 2.8e-08 33.0 0.0 2.3e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EME88785.1 - 2.8e-06 27.4 0.2 5.6e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EME88785.1 - 9.9e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME88785.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EME88785.1 - 0.0035 16.3 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EME88785.1 - 0.0042 16.3 0.1 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EME88785.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EME88785.1 - 0.043 13.9 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EME88785.1 - 0.057 12.3 0.0 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Tic20 PF09685.5 EME88787.1 - 3.6e-06 26.9 2.2 4.7e-06 26.5 1.5 1.1 1 0 0 1 1 1 1 Tic20-like protein AGTRAP PF06396.6 EME88787.1 - 0.029 14.0 1.9 0.042 13.5 1.3 1.2 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Retinal PF15449.1 EME88787.1 - 4.9 4.6 8.0 6 4.3 5.5 1.0 1 0 0 1 1 1 0 Retinal protein Lipase_GDSL_2 PF13472.1 EME88788.1 - 1.4e-14 54.6 0.2 2.8e-14 53.6 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME88788.1 - 1.4e-06 28.3 0.0 8.6e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EME88788.1 - 0.00034 20.4 0.0 0.0006 19.6 0.0 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Tissue_fac PF01108.12 EME88788.1 - 0.086 12.5 0.7 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Tissue factor WW PF00397.21 EME88789.1 - 1.6e-09 37.4 1.8 3.5e-09 36.3 1.2 1.6 1 0 0 1 1 1 1 WW domain DUF4398 PF14346.1 EME88789.1 - 0.0069 16.4 6.1 0.0069 16.4 4.3 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4398) Hydrophobin PF01185.13 EME88790.1 - 0.11 12.9 14.7 0.056 13.8 3.4 2.1 1 1 1 2 2 2 0 Fungal hydrophobin TTL PF03133.10 EME88791.1 - 1.8e-57 194.5 0.0 2.3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EME88791.1 - 2.2e-05 23.3 0.0 0.00025 19.9 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EME88791.1 - 0.00028 20.6 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EME88791.1 - 0.048 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Sugar_tr PF00083.19 EME88793.1 - 4.5e-81 272.7 24.9 5.6e-81 272.4 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME88793.1 - 3.7e-18 65.3 28.0 1.2e-12 47.1 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NYN PF01936.13 EME88794.1 - 8.9e-29 100.6 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 EME88794.1 - 3.1e-10 39.7 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Apc4 PF12896.2 EME88794.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Glyco_transf_11 PF01531.11 EME88796.1 - 0.025 13.6 0.1 0.042 12.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 DUF1691 PF07950.6 EME88797.1 - 8.6e-41 138.3 3.0 6.6e-26 90.4 0.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.3 EME88798.1 - 0.00022 21.2 1.6 0.00035 20.6 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME88798.1 - 0.0052 16.9 0.1 0.0089 16.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Rtf2 PF04641.7 EME88798.1 - 0.058 12.5 0.3 0.068 12.3 0.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CK_II_beta PF01214.13 EME88798.1 - 0.065 12.7 0.0 0.065 12.7 0.0 1.1 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Epimerase PF01370.16 EME88799.1 - 3.2e-18 66.0 0.0 4.9e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME88799.1 - 1.6e-14 53.3 0.0 2.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EME88799.1 - 1.8e-14 54.1 0.0 2.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME88799.1 - 3.3e-11 42.5 0.0 8.7e-10 37.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EME88799.1 - 1.1e-10 41.1 0.1 1.7e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EME88799.1 - 5.5e-06 26.3 0.1 1.6e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EME88799.1 - 4.3e-05 22.5 0.1 6.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.17 EME88799.1 - 0.00014 22.3 0.1 0.0065 16.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EME88799.1 - 0.0057 15.6 0.1 0.008 15.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EME88799.1 - 0.016 14.0 0.1 0.099 11.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EME88799.1 - 0.026 14.1 0.4 0.32 10.6 0.3 2.2 1 1 0 1 1 1 0 KR domain Lipase_GDSL_2 PF13472.1 EME88801.1 - 1.3e-10 41.6 0.2 3.4e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EME88801.1 - 0.00015 21.6 0.3 0.0016 18.3 0.2 2.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1414 PF07208.6 EME88801.1 - 2.4 7.9 4.3 41 3.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1414) HLH PF00010.21 EME88804.1 - 7e-08 32.0 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.21 EME88806.1 - 3.4e-08 33.0 0.1 2.1e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain zf-primase PF09329.6 EME88807.1 - 4.4e-17 61.3 0.7 8.4e-17 60.5 0.5 1.5 1 0 0 1 1 1 1 Primase zinc finger FlxA PF14282.1 EME88807.1 - 0.00081 19.3 1.0 0.00081 19.3 0.7 3.2 4 0 0 4 4 4 1 FlxA-like protein RNase_H2-Ydr279 PF09468.5 EME88808.1 - 2.3e-78 263.4 1.9 2.9e-78 263.1 1.3 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF1682 PF07946.9 EME88808.1 - 0.014 14.2 3.2 0.021 13.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hex_IIIa PF02455.11 EME88808.1 - 0.027 13.1 3.3 0.045 12.4 2.3 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Selenoprotein_S PF06936.6 EME88808.1 - 0.063 12.8 1.7 0.13 11.7 1.2 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) F-box PF00646.28 EME88810.1 - 0.00062 19.3 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain zf-RING_2 PF13639.1 EME88811.1 - 3.3e-13 49.2 5.2 5.9e-13 48.4 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME88811.1 - 1.9e-07 30.6 2.6 3.1e-07 29.9 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EME88811.1 - 2.4e-07 30.7 0.8 4.5e-07 29.8 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME88811.1 - 2.3e-06 27.5 4.5 4e-06 26.7 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME88811.1 - 2.4e-05 23.9 1.9 4.2e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EME88811.1 - 0.00048 19.7 1.6 0.0009 18.8 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME88811.1 - 0.003 17.3 1.5 0.0084 15.9 1.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EME88811.1 - 0.025 14.5 2.6 0.047 13.6 1.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EME88811.1 - 0.038 13.5 2.7 0.066 12.8 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EME88811.1 - 0.3 10.6 2.3 0.67 9.5 1.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2235 PF09994.4 EME88813.1 - 7.7e-60 202.6 0.0 9.4e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Actin PF00022.14 EME88814.1 - 7e-22 77.3 0.0 9.9e-19 67.0 0.0 3.0 3 1 0 3 3 3 2 Actin Ank_2 PF12796.2 EME88815.1 - 5.5e-14 52.2 0.1 1.2e-10 41.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EME88815.1 - 1.1e-11 43.9 2.7 0.0012 18.5 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EME88815.1 - 1e-09 37.6 0.5 0.014 15.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EME88815.1 - 2.2e-09 37.2 1.0 0.002 18.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EME88815.1 - 1.2e-07 32.0 1.4 0.00033 21.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MRP-L28 PF09812.4 EME88816.1 - 7.8e-10 38.7 0.3 2.8e-08 33.7 0.6 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 PGM_PMM_I PF02878.11 EME88817.1 - 1.4e-18 66.7 0.4 5.1e-08 32.4 0.1 3.1 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EME88817.1 - 1.9e-16 60.2 0.1 8.8e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EME88817.1 - 4.2e-10 39.4 0.0 1.5e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EME88817.1 - 0.0011 18.9 0.2 0.0053 16.7 0.1 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DeoC PF01791.4 EME88817.1 - 0.024 13.9 0.1 0.11 11.7 0.0 2.1 1 1 1 2 2 2 0 DeoC/LacD family aldolase His_Phos_2 PF00328.17 EME88821.1 - 9.6e-18 64.6 0.3 5.1e-16 58.9 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3716 PF12511.3 EME88822.1 - 2.2e-08 33.5 6.6 4.4e-08 32.6 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2574 PF10836.3 EME88822.1 - 5.7 6.7 6.1 17 5.2 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2574) Amidase PF01425.16 EME88824.1 - 1.1e-93 314.5 0.2 1.2e-93 314.3 0.1 1.0 1 0 0 1 1 1 1 Amidase CENP-F_N PF10481.4 EME88825.1 - 0.00083 18.8 3.3 0.037 13.4 0.1 2.2 2 0 0 2 2 2 2 Cenp-F N-terminal domain Herpes_UL6 PF01763.11 EME88825.1 - 0.0097 14.1 0.1 0.014 13.5 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like Striatin PF08232.7 EME88825.1 - 0.023 15.0 3.0 0.15 12.3 0.0 2.5 2 1 0 2 2 2 0 Striatin family CENP-F_leu_zip PF10473.4 EME88825.1 - 0.031 14.1 0.8 0.031 14.1 0.6 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BBP1_C PF15272.1 EME88825.1 - 0.079 12.5 1.2 0.16 11.5 0.8 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF1319 PF07028.6 EME88825.1 - 0.16 12.1 2.5 0.17 12.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) AKNA PF12443.3 EME88825.1 - 0.21 11.5 2.0 0.24 11.4 0.4 1.8 2 0 0 2 2 2 0 AT-hook-containing transcription factor DivIC PF04977.10 EME88825.1 - 0.24 10.9 5.0 0.21 11.0 0.8 2.1 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 EME88825.1 - 4.7 6.9 15.1 0.11 12.3 2.4 2.5 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ISN1 PF06437.6 EME88827.1 - 1.4e-187 623.4 0.0 1.6e-187 623.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ribosomal_S5 PF00333.15 EME88827.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Med17 PF10156.4 EME88828.1 - 2.3e-71 240.4 0.2 3.2e-71 240.0 0.1 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Sec16_N PF12935.2 EME88828.1 - 0.026 14.3 0.9 0.026 14.3 0.6 2.0 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus Melibiase PF02065.13 EME88829.1 - 4e-09 35.6 0.1 3.5e-08 32.5 0.0 2.2 2 1 0 2 2 2 1 Melibiase zf-H2C2_2 PF13465.1 EME88830.1 - 1.6e-08 34.4 10.6 2.2e-06 27.6 3.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME88830.1 - 1.2e-06 28.4 16.2 0.0035 17.5 5.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EME88830.1 - 5.9e-06 26.3 17.8 0.017 15.4 6.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EME88830.1 - 0.0001 21.2 2.0 0.16 10.8 0.4 2.7 1 1 0 2 2 2 2 Fungal specific transcription factor domain zf-met PF12874.2 EME88830.1 - 0.011 15.9 6.1 0.027 14.6 4.2 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME88830.1 - 0.05 13.7 12.2 0.49 10.6 3.9 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fe-S_biosyn PF01521.15 EME88832.1 - 1.8e-11 43.9 0.0 1.1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis Clathrin-link PF09268.5 EME88832.1 - 0.11 11.5 0.1 0.34 9.9 0.1 1.7 2 0 0 2 2 2 0 Clathrin, heavy-chain linker PGM_PMM_I PF02878.11 EME88833.1 - 1e-33 115.7 0.1 1.5e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EME88833.1 - 1.5e-24 86.2 0.0 2.5e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EME88833.1 - 4.2e-15 55.9 0.1 1e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EME88833.1 - 1.5e-10 40.9 0.0 3.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain p450 PF00067.17 EME88834.1 - 4e-62 210.2 0.0 5.2e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EME88837.1 - 1.2e-15 57.2 0.1 1.7e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.1 EME88838.1 - 2.2e-17 63.6 5.1 9.6e-16 58.2 1.9 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EME88838.1 - 7.5e-13 48.1 1.7 8.8e-13 47.9 0.3 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EME88838.1 - 3.3e-12 45.5 4.8 2.6e-10 39.3 2.9 2.7 2 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EME88838.1 - 5.6e-10 39.2 18.2 5.6e-10 39.2 12.6 2.7 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EME88838.1 - 1.1e-05 25.1 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 SeleniumBinding PF11524.3 EME88838.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Selenium binding protein Y_phosphatase PF00102.22 EME88840.1 - 2.4e-60 203.8 0.8 3.1e-52 177.2 0.2 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 EME88840.1 - 1.3e-11 44.8 0.1 9.3e-10 38.8 0.0 3.0 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.15 EME88840.1 - 0.0042 16.6 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EME88840.1 - 0.01 16.0 0.4 0.028 14.6 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family CCAP PF11105.3 EME88840.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Acetyltransf_3 PF13302.1 EME88841.1 - 2.2e-19 70.0 0.0 2.8e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME88841.1 - 2.2e-13 50.0 0.1 4.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EME88841.1 - 2.2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME88841.1 - 0.00015 21.7 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME88841.1 - 0.00033 20.7 0.0 0.00056 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME88841.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME88841.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein HlyIII PF03006.15 EME88842.1 - 4.6e-64 215.8 17.4 5.4e-64 215.6 12.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4131 PF13567.1 EME88842.1 - 6 6.2 8.7 7.2 5.9 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) SAC3_GANP PF03399.11 EME88843.1 - 0.00019 21.0 0.2 0.00027 20.5 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family MmgE_PrpD PF03972.9 EME88844.1 - 5.9e-61 205.9 0.0 6.8e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Myc_N PF01056.13 EME88844.1 - 0.0046 16.1 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Myc amino-terminal region APH PF01636.18 EME88846.1 - 1.9e-15 57.2 0.2 2.9e-15 56.6 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME88846.1 - 2.3e-07 30.6 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EME88846.1 - 0.078 11.6 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) P53_tetramer PF07710.6 EME88846.1 - 0.087 11.9 0.3 12 5.0 0.0 2.3 2 0 0 2 2 2 0 P53 tetramerisation motif Ribosomal_L13e PF01294.13 EME88848.1 - 2.5e-65 219.2 9.6 6.4e-65 217.9 6.6 1.7 1 1 0 1 1 1 1 Ribosomal protein L13e DNA_pol_B PF00136.16 EME88849.1 - 9.5e-114 380.7 2.3 1.5e-113 380.0 1.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EME88849.1 - 1.9e-55 187.1 0.0 4.9e-55 185.8 0.0 1.8 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EME88849.1 - 2.2e-38 131.9 0.0 4e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EME88849.1 - 3.9e-24 84.2 13.4 6.3e-24 83.5 6.2 3.1 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal NCKAP5 PF15246.1 EME88849.1 - 0.00065 19.1 0.5 0.0019 17.6 0.3 1.7 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein Tnp_DNA_bind PF14706.1 EME88849.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Transposase DNA-binding WD40 PF00400.27 EME88850.1 - 7.8e-09 35.0 11.4 0.056 13.3 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Per1 PF04080.8 EME88851.1 - 2.1e-104 348.6 5.8 2.7e-104 348.3 4.0 1.1 1 0 0 1 1 1 1 Per1-like Tyrosinase PF00264.15 EME88852.1 - 4.7e-36 125.0 6.2 6.1e-36 124.6 4.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase YhhN PF07947.9 EME88852.1 - 0.13 11.5 0.2 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 YhhN-like protein F-box PF00646.28 EME88853.1 - 7.9e-09 34.9 0.0 1.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EME88853.1 - 1.3e-05 24.7 0.1 1.3e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like DUF3079 PF11278.3 EME88853.1 - 0.087 12.3 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) PRANC PF09372.5 EME88853.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Na_Ca_ex PF01699.19 EME88854.1 - 2.2e-39 134.2 33.7 7.8e-21 74.1 11.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Rax2 PF12768.2 EME88854.1 - 0.84 8.7 3.3 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DUF3087 PF11286.3 EME88854.1 - 8 5.6 7.3 0.45 9.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) GST_N_3 PF13417.1 EME88855.1 - 4.8e-11 42.7 0.1 1e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME88855.1 - 7.2e-09 35.5 0.1 1.4e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME88855.1 - 0.0028 17.5 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Metallophos PF00149.23 EME88856.1 - 1.8e-08 34.0 2.5 3.1e-08 33.2 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EME88856.1 - 0.04 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CRAL_TRIO PF00650.15 EME88859.1 - 1.4e-10 40.8 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GcrA PF07750.6 EME88860.1 - 8.1e-07 29.3 0.0 0.00042 20.5 0.0 2.9 3 0 0 3 3 3 2 GcrA cell cycle regulator Myb_DNA-bind_6 PF13921.1 EME88860.1 - 3.1e-05 23.9 4.3 0.0061 16.6 0.0 3.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain HTH_38 PF13936.1 EME88860.1 - 3.4e-05 23.2 0.1 0.0051 16.3 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_7 PF02796.10 EME88860.1 - 0.0017 18.1 0.0 4 7.3 0.0 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 EME88860.1 - 0.005 17.6 7.8 0.01 16.6 0.7 4.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_23 PF13384.1 EME88860.1 - 0.013 15.1 0.1 0.1 12.2 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EME88860.1 - 0.081 12.4 0.0 0.52 9.8 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 DUF3292 PF11696.3 EME88861.1 - 2.4e-222 739.3 0.0 6.8e-123 410.8 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) BTB PF00651.26 EME88862.1 - 0.0002 21.3 0.4 0.0025 17.7 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain YjbR PF04237.8 EME88862.1 - 0.092 13.1 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 YjbR TPR_11 PF13414.1 EME88864.1 - 0.0045 16.6 3.7 5 6.8 0.0 4.9 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EME88864.1 - 1.2 8.8 6.1 30 4.4 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 EME88865.1 - 3.1e-150 500.3 0.0 3.9e-150 500.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EME88865.1 - 5.9e-08 32.6 0.9 1.4 9.7 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME88865.1 - 8.6e-05 22.1 0.0 0.22 11.2 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EME88865.1 - 0.00024 21.3 0.1 0.072 13.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EME88865.1 - 0.00029 20.5 1.0 0.069 13.1 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME88865.1 - 0.026 14.3 0.0 1.6 8.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME88865.1 - 0.05 14.2 2.0 8.1 7.2 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EME88866.1 - 5.6e-35 120.6 27.8 5.6e-35 120.6 19.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EME88866.1 - 0.012 15.1 3.7 0.043 13.3 2.6 2.0 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Zn_clus PF00172.13 EME88868.1 - 2.9e-06 27.0 7.1 4.7e-06 26.3 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EME88869.1 - 1.3e-43 148.4 0.0 9.3e-43 145.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME88869.1 - 7.8e-23 80.1 0.0 1.7e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EME88869.1 - 0.0048 15.7 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HMG_box_2 PF09011.5 EME88870.1 - 6.1e-13 48.9 4.5 3e-07 30.7 0.5 3.9 3 1 1 4 4 4 2 HMG-box domain HMG_box PF00505.14 EME88870.1 - 3e-08 33.7 5.8 3.3e-06 27.2 0.3 4.2 4 2 0 4 4 4 2 HMG (high mobility group) box V_ATPase_I PF01496.14 EME88870.1 - 2.3 5.9 7.0 3 5.5 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PS_Dcarbxylase PF02666.10 EME88871.1 - 8e-53 178.7 0.0 1.3e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EME88871.1 - 7.5e-41 137.8 0.6 2.9e-22 78.3 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EME88871.1 - 0.0028 17.7 0.4 0.0077 16.3 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EME88871.1 - 0.0065 15.7 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 EME88871.1 - 0.011 14.9 0.0 0.038 13.3 0.0 2.0 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EME88871.1 - 0.012 15.3 0.2 0.071 13.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain CDC45 PF02724.9 EME88871.1 - 0.066 11.2 7.1 0.11 10.4 4.9 1.3 1 0 0 1 1 1 0 CDC45-like protein JAB PF01398.16 EME88873.1 - 9.8e-08 31.7 0.0 9e-07 28.6 0.0 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 EME88873.1 - 0.4 9.8 5.4 0.42 9.8 2.1 2.0 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal DUF3523 PF12037.3 EME88873.1 - 1.7 7.5 13.2 3.2 6.6 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) GST_N_3 PF13417.1 EME88874.1 - 2.6e-24 85.2 0.0 4.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EME88874.1 - 2.9e-14 52.7 0.0 5.5e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EME88874.1 - 1.8e-06 27.7 0.1 2.7e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EME88874.1 - 3.6e-06 27.0 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ATP_bind_1 PF03029.12 EME88876.1 - 1e-70 238.0 0.1 1.7e-70 237.2 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EME88876.1 - 4.7e-06 26.1 0.4 0.0049 16.3 0.0 3.0 3 1 0 3 3 2 2 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EME88876.1 - 9.6e-05 21.9 0.0 0.00016 21.2 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EME88876.1 - 0.00012 21.0 0.1 0.0097 14.7 0.1 2.2 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 EME88876.1 - 0.00025 20.7 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ras PF00071.17 EME88876.1 - 0.00026 20.4 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EME88876.1 - 0.00027 20.8 0.0 0.00099 19.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EME88876.1 - 0.00028 21.0 0.0 0.00087 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EME88876.1 - 0.0023 17.8 0.0 0.0069 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EME88876.1 - 0.003 18.0 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NB-ARC PF00931.17 EME88876.1 - 0.0037 16.1 0.2 0.015 14.1 0.0 2.0 2 1 1 3 3 3 1 NB-ARC domain AAA_17 PF13207.1 EME88876.1 - 0.0053 17.5 0.0 0.023 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EME88876.1 - 0.007 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EME88876.1 - 0.0074 16.6 1.6 0.046 14.0 0.8 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EME88876.1 - 0.016 14.6 0.8 0.093 12.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.14 EME88876.1 - 0.017 14.5 0.1 0.48 9.8 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EME88876.1 - 0.018 14.3 0.0 0.61 9.3 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 EME88876.1 - 0.02 15.0 0.1 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 EME88876.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EME88876.1 - 0.023 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EME88876.1 - 0.024 13.8 0.0 0.91 8.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 EME88876.1 - 0.032 13.6 0.1 0.16 11.4 0.0 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EME88876.1 - 0.039 13.4 0.3 0.4 10.1 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EME88876.1 - 0.043 12.8 0.1 0.25 10.2 0.0 2.2 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 EME88876.1 - 0.044 13.3 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EME88876.1 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 EME88876.1 - 0.079 11.6 3.9 0.71 8.4 0.0 2.9 2 1 0 3 3 3 0 G-protein alpha subunit AAA_18 PF13238.1 EME88876.1 - 0.084 13.1 0.0 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EME88876.1 - 0.11 11.7 0.0 5.3 6.2 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family OmpH PF03938.9 EME88876.1 - 0.26 11.2 6.1 0.61 10.0 4.2 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.18 EME88876.1 - 7.1 6.4 6.9 0.96 9.2 0.1 2.8 2 1 1 3 3 3 0 Dynamin family CwfJ_C_1 PF04677.10 EME88877.1 - 2.3e-26 91.8 0.1 4.3e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EME88877.1 - 2.3e-21 76.1 0.1 1.1e-20 73.9 0.1 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 PI-PLC-X PF00388.14 EME88878.1 - 1.9e-13 50.0 0.0 2.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DNA_pol_A_exo1 PF01612.15 EME88879.1 - 7.3e-13 48.3 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease TEX13 PF15186.1 EME88879.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family CPL PF08144.6 EME88880.1 - 1.2e-19 70.5 0.0 8.7e-19 67.8 0.0 2.4 2 1 1 3 3 3 1 CPL (NUC119) domain PAP_central PF04928.12 EME88880.1 - 0.00096 18.0 0.7 0.63 8.7 0.1 3.0 3 0 0 3 3 3 3 Poly(A) polymerase central domain HALZ PF02183.13 EME88881.1 - 0.0021 17.7 19.8 0.071 12.8 0.7 5.1 4 2 1 5 5 5 2 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EME88881.1 - 0.0046 16.6 2.1 0.0046 16.6 1.5 4.3 2 2 2 4 4 4 1 TPR/MLP1/MLP2-like protein DUF2852 PF11014.3 EME88881.1 - 0.046 13.6 0.3 0.18 11.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) bZIP_1 PF00170.16 EME88881.1 - 0.11 12.4 19.0 0.14 12.1 0.8 4.7 4 2 0 4 4 4 0 bZIP transcription factor bZIP_2 PF07716.10 EME88881.1 - 0.77 9.6 18.1 0.65 9.8 0.9 4.8 4 0 0 4 4 4 0 Basic region leucine zipper DUF2580 PF10824.3 EME88881.1 - 1.6 9.1 10.5 1.7 9.0 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) TMF_DNA_bd PF12329.3 EME88881.1 - 2.1 8.1 18.8 0.15 11.8 1.5 4.4 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Shugoshin_N PF07558.6 EME88881.1 - 2.2 8.0 6.6 14 5.4 0.2 3.9 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region DUF2935 PF11155.3 EME88881.1 - 3.1 7.8 10.1 0.85 9.7 1.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF972 PF06156.8 EME88881.1 - 3.2 8.1 25.5 1.2 9.5 4.8 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF972) MSG PF02349.10 EME88881.1 - 7.7 6.5 11.9 0.55 10.2 4.3 2.1 2 0 0 2 2 2 0 Major surface glycoprotein Glyco_hydro_17 PF00332.13 EME88882.1 - 2.5e-23 82.6 0.4 5.3e-21 74.9 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Nop52 PF05997.7 EME88883.1 - 1e-58 198.3 0.0 1.3e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SET PF00856.23 EME88884.1 - 1e-25 90.9 0.6 2.6e-25 89.6 0.4 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EME88884.1 - 1e-16 61.0 2.4 1.6e-16 60.3 0.3 2.3 2 0 0 2 2 2 1 Pre-SET motif Sod_Cu PF00080.15 EME88885.1 - 7.7e-17 61.7 0.2 9.9e-17 61.4 0.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) 14-3-3 PF00244.15 EME88886.1 - 4.9e-10 38.8 2.2 5.6e-10 38.7 0.0 2.0 3 0 0 3 3 3 1 14-3-3 protein PTN_MK_C PF01091.13 EME88887.1 - 6.6 6.7 6.9 1.6 8.7 0.1 2.8 2 1 1 3 3 3 0 PTN/MK heparin-binding protein family, C-terminal domain DnaJ PF00226.26 EME88889.1 - 1.5e-08 34.2 0.1 4.5e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Pam16 PF03656.8 EME88889.1 - 0.00075 19.2 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 Pam16 Ribosomal_L24e PF01246.15 EME88890.1 - 9.7e-32 108.6 2.0 2.1e-31 107.5 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e V-ATPase_G PF03179.10 EME88890.1 - 0.024 14.9 4.3 2 8.7 0.2 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF2175 PF09943.4 EME88890.1 - 4.1 7.5 7.0 0.62 10.1 0.9 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3431 PF11913.3 EME88891.1 - 1.5e-45 155.3 2.0 1.9e-45 155.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4109 PF13397.1 EME88891.1 - 0.056 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) DHDPS PF00701.17 EME88892.1 - 1.2e-37 129.0 0.0 1.5e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pil1 PF13805.1 EME88893.1 - 3.5e-154 511.7 0.2 4.2e-154 511.4 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EME88893.1 - 0.015 14.6 2.7 0.016 14.5 0.8 1.8 1 1 1 2 2 2 0 FAM92 protein Ribophorin_II PF05817.9 EME88895.1 - 2.5e-27 95.3 0.0 2.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II MutS_V PF00488.16 EME88896.1 - 4.9e-83 278.1 0.1 7.5e-83 277.5 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EME88896.1 - 1.5e-48 165.3 0.0 2.7e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EME88896.1 - 4.7e-33 113.5 0.1 1.7e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EME88896.1 - 4.5e-16 58.7 0.1 9.7e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EME88896.1 - 3.7e-09 36.7 0.0 8.9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EME88896.1 - 0.0035 16.8 0.1 0.0084 15.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Shugoshin_C PF07557.6 EME88896.1 - 0.011 15.2 0.0 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 Shugoshin C terminus AAA_23 PF13476.1 EME88896.1 - 0.017 15.4 0.5 0.017 15.4 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EME88896.1 - 0.033 14.1 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EME88897.1 - 9.7e-72 241.5 0.0 1.4e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) adh_short PF00106.20 EME88898.1 - 5.2e-18 65.5 0.1 7.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME88898.1 - 1.7e-09 37.5 0.1 2.6e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EME88898.1 - 0.035 13.1 0.1 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EME88898.1 - 0.044 12.7 0.9 0.24 10.2 0.6 2.1 1 1 0 1 1 1 0 Male sterility protein YaeQ PF07152.7 EME88898.1 - 0.091 12.0 0.1 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 YaeQ protein Zip PF02535.17 EME88899.1 - 2.7e-59 200.7 0.9 3.3e-59 200.4 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Cmc1 PF08583.5 EME88900.1 - 0.0054 16.4 1.4 0.016 14.9 0.9 1.9 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like AT_hook PF02178.14 EME88901.1 - 0.16 11.7 32.4 0.034 13.8 1.7 4.6 4 0 0 4 4 4 0 AT hook motif bZIP_2 PF07716.10 EME88902.1 - 0.00014 21.5 7.1 0.00031 20.5 4.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME88902.1 - 0.078 13.2 2.7 0.2 11.9 1.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 EME88902.1 - 0.38 10.7 6.1 0.93 9.4 4.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor Toxin_33 PF08121.6 EME88903.1 - 2.3 7.8 7.7 1.2 8.7 2.9 2.5 1 1 0 1 1 1 0 Waglerin family SGL PF08450.7 EME88904.1 - 4.9e-62 209.5 0.0 6.3e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region zf-GRF PF06839.7 EME88904.1 - 0.1 12.5 1.1 3.2 7.7 0.3 2.4 2 0 0 2 2 2 0 GRF zinc finger Aldedh PF00171.17 EME88905.1 - 2e-166 553.9 0.0 2.3e-166 553.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EME88905.1 - 0.002 17.4 0.0 0.0097 15.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Glyco_trans_1_4 PF13692.1 EME88905.1 - 0.017 15.2 0.2 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 TRI12 PF06609.8 EME88906.1 - 1.2e-23 83.2 28.6 1.6e-23 82.8 19.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME88906.1 - 5.9e-23 81.1 80.3 1.4e-19 70.0 32.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Gemini_mov PF01708.11 EME88906.1 - 0.39 10.3 3.7 0.66 9.5 0.0 2.8 3 0 0 3 3 3 0 Geminivirus putative movement protein Raffinose_syn PF05691.7 EME88908.1 - 1.2e-50 171.9 3.2 2.1e-47 161.1 1.6 2.9 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EME88908.1 - 0.00024 19.9 0.4 0.00042 19.1 0.3 1.3 1 0 0 1 1 1 1 Melibiase WD40 PF00400.27 EME88909.1 - 1.2e-07 31.2 7.8 0.0018 18.0 0.1 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EME88909.1 - 0.0028 17.1 0.1 0.071 12.5 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain YL1 PF05764.8 EME88909.1 - 0.11 12.1 8.0 0.16 11.5 5.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EME88909.1 - 0.12 10.2 2.7 0.14 10.0 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EME88909.1 - 2.7 7.5 6.9 3.5 7.1 3.5 2.0 2 0 0 2 2 2 0 Nucleoplasmin Cutinase PF01083.17 EME88910.1 - 2.6e-34 118.5 6.0 2.8e-34 118.3 4.2 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EME88910.1 - 5.3e-05 22.8 0.3 6.1e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peripla_BP_4 PF13407.1 EME88910.1 - 0.0035 16.7 0.2 0.0047 16.3 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Abhydrolase_5 PF12695.2 EME88910.1 - 0.0054 16.4 0.8 0.0063 16.2 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EME88910.1 - 0.0059 16.8 0.1 0.0066 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 EME88910.1 - 0.0075 15.7 0.4 0.0092 15.4 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_9 PF10081.4 EME88910.1 - 0.011 14.5 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_2 PF02230.11 EME88910.1 - 0.034 13.5 0.1 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EME88910.1 - 0.05 13.4 0.2 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EME88910.1 - 0.13 11.8 0.1 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_43 PF04616.9 EME88912.1 - 8.7e-26 90.6 2.3 5.3e-25 88.0 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.20 EME88913.1 - 1.9e-29 102.7 2.1 2.4e-29 102.3 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME88913.1 - 4.3e-28 98.7 0.1 5.1e-28 98.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME88913.1 - 9.3e-15 54.7 1.4 1.4e-14 54.1 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EME88913.1 - 0.034 13.7 0.2 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EME88913.1 - 0.04 13.4 0.4 0.14 11.6 0.3 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EME88913.1 - 0.11 11.9 0.2 0.39 10.1 0.1 1.9 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME88913.1 - 0.31 11.0 2.3 0.32 10.9 0.5 1.8 2 0 0 2 2 2 0 NADH(P)-binding Cgr1 PF03879.9 EME88915.1 - 6.7e-36 122.7 27.3 8.3e-36 122.4 18.9 1.1 1 0 0 1 1 1 1 Cgr1 family SprA-related PF12118.3 EME88915.1 - 0.081 12.2 12.7 0.098 11.9 8.8 1.0 1 0 0 1 1 1 0 SprA-related family PRP1_N PF06424.7 EME88915.1 - 0.2 11.9 11.5 0.28 11.5 8.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Prismane PF03063.15 EME88915.1 - 0.26 9.6 4.2 0.3 9.3 2.9 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Chisel PF15355.1 EME88915.1 - 1 9.4 5.7 0.17 11.8 0.8 1.9 1 1 1 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel APG6 PF04111.7 EME88915.1 - 1.6 7.6 9.1 1.7 7.6 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RR_TM4-6 PF06459.7 EME88915.1 - 2 8.2 10.5 2.4 7.9 7.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Adeno_VII PF03228.9 EME88915.1 - 2.8 8.5 13.4 3.6 8.1 9.3 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII Sec62 PF03839.11 EME88915.1 - 6 6.2 12.2 7.4 5.9 8.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Mito_carr PF00153.22 EME88916.1 - 1.3e-64 213.9 0.8 3.6e-22 77.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EME88917.1 - 4.4e-15 55.2 0.1 7.4e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88917.1 - 1.4e-06 28.1 11.7 2.3e-06 27.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EME88917.1 - 0.11 12.1 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 ALF PF03752.8 EME88917.1 - 0.82 9.5 3.9 0.38 10.6 0.8 1.8 2 0 0 2 2 2 0 Short repeats of unknown function tRNA-synt_2 PF00152.15 EME88918.1 - 4.8e-75 252.4 0.0 7.6e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EME88918.1 - 1.4e-14 53.5 0.0 1.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EME88918.1 - 4.7e-06 26.3 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME88918.1 - 0.00017 20.8 0.9 0.32 10.1 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Carb_kinase PF01256.12 EME88919.1 - 3.1e-57 193.6 0.1 3.9e-57 193.3 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EME88919.1 - 9.6e-05 21.6 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EME88919.1 - 0.00061 19.0 0.1 0.0015 17.7 0.1 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PRKCSH PF07915.8 EME88921.1 - 2.7e-17 63.3 0.2 7.9e-17 61.8 0.0 1.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EME88921.1 - 0.008 15.6 0.1 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ubiquitin_3 PF14836.1 EME88921.1 - 0.025 14.2 0.0 0.065 12.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain ATG27 PF09451.5 EME88921.1 - 0.051 12.8 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 UAA PF08449.6 EME88922.1 - 3.6e-78 262.5 15.0 4.5e-78 262.2 10.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EME88922.1 - 1.1e-05 25.0 2.9 1.1e-05 25.0 2.0 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EME88922.1 - 5.7e-05 22.3 0.8 5.7e-05 22.3 0.5 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EME88922.1 - 0.00047 20.1 27.9 0.18 11.8 5.3 3.5 2 1 1 3 3 3 3 EamA-like transporter family EmrE PF13536.1 EME88922.1 - 0.24 11.6 23.9 1.2 9.4 4.3 3.5 2 2 1 3 3 3 0 Multidrug resistance efflux transporter HLH PF00010.21 EME88923.1 - 8.2e-17 60.6 0.1 2.9e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain BRO1 PF03097.13 EME88923.1 - 0.043 12.5 0.0 0.075 11.7 0.0 1.4 1 1 0 1 1 1 0 BRO1-like domain DUF972 PF06156.8 EME88923.1 - 0.072 13.4 0.9 0.18 12.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EME88923.1 - 0.19 12.0 3.6 0.54 10.5 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Phosphodiest PF01663.17 EME88924.1 - 1.2e-47 162.9 0.2 1.5e-47 162.7 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EME88924.1 - 0.0004 19.6 0.0 0.00057 19.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.11 EME88925.1 - 2.7e-14 52.6 54.8 3e-13 49.2 24.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EME88925.1 - 0.002 16.6 8.2 0.0047 15.4 5.7 1.6 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like p450 PF00067.17 EME88926.1 - 3.1e-44 151.2 0.0 3.9e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CENP-K PF11802.3 EME88926.1 - 0.17 11.0 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K OmpW PF03922.9 EME88927.1 - 0.0017 18.0 0.0 0.0019 17.9 0.0 1.0 1 0 0 1 1 1 1 OmpW family Neugrin PF06413.6 EME88928.1 - 1.4e-11 44.6 2.1 1.4e-11 44.6 1.4 2.6 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EME88928.1 - 5.9e-06 26.3 10.6 5.9e-06 26.3 7.4 3.7 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M26_C PF07580.9 EME88928.1 - 0.0072 14.6 4.3 0.0098 14.2 3.0 1.1 1 0 0 1 1 1 1 M26 IgA1-specific Metallo-endopeptidase C-terminal region DUF342 PF03961.8 EME88928.1 - 0.15 10.4 11.5 0.22 9.9 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lipase_GDSL_3 PF14606.1 EME88928.1 - 0.33 10.6 2.9 0.62 9.7 2.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4599 PF15371.1 EME88928.1 - 1.3 9.0 12.2 11 6.1 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) CytochromB561_N PF09786.4 EME88928.1 - 4.9 5.4 18.8 0.29 9.5 6.9 2.0 1 1 1 2 2 2 0 Cytochrome B561, N terminal CPDase PF07823.6 EME88929.1 - 5.4e-26 91.2 0.0 5.9e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EME88929.1 - 6.6e-08 32.4 0.3 0.0032 17.2 0.1 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Rxt3 PF08642.5 EME88930.1 - 3.2e-23 82.1 0.0 7.7e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EME88930.1 - 2.7e-06 27.2 0.0 2.3e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 LCCL domain CUB_2 PF02408.15 EME88930.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 CUB-like domain CLN3 PF02487.12 EME88931.1 - 3.5e-102 342.2 8.9 5.5e-96 321.8 0.6 2.1 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 EME88931.1 - 0.065 11.9 32.3 0.013 14.2 4.4 3.0 1 1 0 1 1 1 0 Major Facilitator Superfamily RRM_1 PF00076.17 EME88934.1 - 2.4e-17 62.3 0.0 3.4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME88934.1 - 3.7e-12 46.0 0.0 1e-11 44.6 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME88934.1 - 4.1e-09 36.1 0.0 6.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EME88934.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.27 EME88935.1 - 4.3e-18 64.4 9.2 0.008 16.0 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 EME88935.1 - 1.2e-07 31.5 2.7 1.2e-07 31.5 1.9 2.4 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) eIF2A PF08662.6 EME88935.1 - 1.6e-05 24.6 1.0 0.00044 20.0 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Sec16_C PF12931.2 EME88935.1 - 7.6e-05 22.5 0.4 0.00018 21.3 0.2 1.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 EME88935.1 - 0.0011 18.4 0.0 0.42 10.1 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.10 EME88935.1 - 0.011 15.5 1.3 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 Prp18 domain PEP-utilisers_N PF05524.8 EME88935.1 - 0.043 13.6 0.7 5.1 6.9 0.0 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal TPR_1 PF00515.23 EME88936.1 - 3.1e-55 181.6 21.4 8.1e-09 34.7 0.0 10.8 11 1 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EME88936.1 - 9.9e-50 162.5 13.5 1.4e-06 27.7 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EME88936.1 - 1.6e-47 158.9 15.1 1.7e-12 46.7 0.3 6.4 3 2 2 6 6 6 5 TPR repeat TPR_8 PF13181.1 EME88936.1 - 7e-40 131.8 11.6 6e-06 25.6 0.0 10.3 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EME88936.1 - 3.1e-31 107.3 16.9 1.6e-07 31.8 0.0 6.9 5 2 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EME88936.1 - 5.2e-30 103.2 18.2 9.1e-07 28.7 0.0 7.2 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EME88936.1 - 2.4e-29 99.0 16.5 3.3e-05 23.7 0.0 11.1 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EME88936.1 - 1.8e-26 90.2 9.2 0.00019 21.7 0.0 10.2 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 EME88936.1 - 1.9e-23 80.3 9.1 0.0009 18.8 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EME88936.1 - 4.5e-23 81.3 16.9 3.4e-06 27.2 0.0 6.9 5 2 0 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EME88936.1 - 9.7e-23 79.0 18.0 0.00046 20.4 0.0 10.3 11 0 0 11 11 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EME88936.1 - 1.3e-13 50.9 11.0 1.1e-08 35.0 1.4 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EME88936.1 - 4.3e-13 48.9 11.5 0.00041 20.1 0.1 6.4 2 1 7 9 9 8 6 Tetratricopeptide repeat TPR_15 PF13429.1 EME88936.1 - 1.6e-08 33.9 11.9 0.00029 19.9 3.1 4.8 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 EME88936.1 - 1.6e-05 24.8 12.4 0.094 12.6 2.2 4.5 3 2 2 5 5 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME88936.1 - 3.9e-05 23.4 0.1 2.7 7.9 0.0 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EME88936.1 - 0.00061 19.8 0.8 0.19 11.8 0.0 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 EME88936.1 - 0.0061 16.0 1.8 0.94 8.8 0.0 3.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 EME88936.1 - 0.018 13.8 1.9 6 5.5 0.0 2.9 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) GAS PF13851.1 EME88936.1 - 0.056 12.6 0.2 0.13 11.4 0.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Clathrin PF00637.15 EME88936.1 - 0.065 12.8 1.4 9.1 5.8 0.0 3.5 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_10 PF13374.1 EME88936.1 - 0.12 12.3 11.0 19 5.3 0.1 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.12 EME88936.1 - 0.63 10.3 15.7 6.1 7.1 0.1 5.0 4 2 2 6 6 5 0 Bacterial transcriptional activator domain MIT PF04212.13 EME88936.1 - 3.9 7.4 16.7 4.2 7.3 1.1 5.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain adh_short PF00106.20 EME88937.1 - 4e-07 30.1 0.0 7.6e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME88937.1 - 0.0069 16.1 0.0 0.021 14.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ERAP1_C PF11838.3 EME88937.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Fungal_trans_2 PF11951.3 EME88938.1 - 8e-51 172.8 5.6 3.9e-50 170.5 3.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME88938.1 - 5.6e-05 22.9 5.6 0.00012 21.9 3.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.6 EME88938.1 - 0.0092 16.8 1.9 0.23 12.3 0.0 3.2 3 0 0 3 3 3 1 EthD domain WLM PF08325.5 EME88938.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 WLM domain His_Phos_1 PF00300.17 EME88939.1 - 6.6e-24 84.8 0.1 9.3e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MRG PF05712.8 EME88941.1 - 1.6e-50 170.7 0.0 2.6e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EME88941.1 - 3.4e-08 33.0 3.0 5.5e-08 32.3 1.1 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Mto2_bdg PF12808.2 EME88941.1 - 0.047 13.8 2.5 0.15 12.1 1.4 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Metal_resist PF13801.1 EME88941.1 - 0.3 11.0 2.7 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance SART-1 PF03343.8 EME88942.1 - 2.4e-132 442.3 79.3 2.7e-132 442.2 55.0 1.0 1 0 0 1 1 1 1 SART-1 family Acetyltransf_3 PF13302.1 EME88943.1 - 3.1e-17 63.0 0.3 3.6e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME88943.1 - 9.9e-05 22.3 0.1 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EME88943.1 - 0.0057 16.6 0.0 0.0059 16.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME88943.1 - 0.022 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EME88944.1 - 4.7e-30 104.4 37.7 4.7e-30 104.4 26.1 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME88944.1 - 3.1e-09 35.9 27.8 1.2e-08 34.0 19.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter CytB6-F_Fe-S PF08802.5 EME88944.1 - 2.4 8.2 6.7 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit PTH2 PF01981.11 EME88946.1 - 1.8e-46 156.6 0.1 2.2e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sulfatase PF00884.18 EME88947.1 - 6.4e-51 173.3 0.0 8.6e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EME88947.1 - 4.7e-20 71.1 2.1 4.7e-20 71.1 1.4 1.9 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EME88947.1 - 4.2e-12 46.0 0.3 1.7e-11 44.0 0.2 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EME88947.1 - 0.0011 17.4 0.0 0.0017 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EME88947.1 - 0.011 16.0 0.2 0.039 14.2 0.1 2.0 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 EME88947.1 - 0.019 15.1 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF1501 PF07394.7 EME88947.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PIR PF00399.14 EME88948.1 - 1.8e-15 55.6 50.5 2.3e-05 23.5 3.3 5.8 4 1 2 6 6 6 4 Yeast PIR protein repeat Tim44 PF04280.10 EME88949.1 - 3.1e-31 108.3 1.7 3.7e-31 108.0 0.0 2.1 3 0 0 3 3 3 1 Tim44-like domain Ribosomal_S11 PF00411.14 EME88950.1 - 2e-07 31.1 0.1 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Abhydrolase_5 PF12695.2 EME88951.1 - 0.00023 20.9 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME88951.1 - 0.00069 18.9 0.1 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EME88951.1 - 0.0064 15.7 0.1 0.051 12.8 0.0 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase 3Beta_HSD PF01073.14 EME88952.1 - 1.2e-56 191.4 0.0 2.4e-56 190.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EME88952.1 - 1.4e-27 96.6 0.0 1.9e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EME88952.1 - 7.8e-18 64.3 1.0 4.1e-13 48.8 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EME88952.1 - 1.3e-13 51.3 0.1 1.8e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EME88952.1 - 2.6e-13 49.5 0.1 5.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EME88952.1 - 6.9e-09 35.0 0.5 4.8e-08 32.2 0.3 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EME88952.1 - 1.2e-07 31.7 0.2 4.3e-07 29.9 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME88952.1 - 1.1e-06 28.3 0.4 6.6e-06 25.8 0.3 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EME88952.1 - 2.2e-05 23.8 0.1 3.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Ldh_1_N PF00056.18 EME88952.1 - 0.04 13.7 0.1 0.11 12.3 0.0 1.8 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain HECT_2 PF09814.4 EME88953.1 - 1.3e-63 214.9 0.1 1.4e-63 214.7 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Mut7-C PF01927.11 EME88953.1 - 0.0066 16.4 0.3 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 Mut7-C RNAse domain Ribosomal_S27e PF01667.12 EME88953.1 - 0.47 10.0 2.4 1.7 8.2 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 Titin_Z PF09042.6 EME88954.1 - 0.069 12.7 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 Titin Z zf-C2H2 PF00096.21 EME88956.1 - 0.0038 17.4 5.2 0.0038 17.4 3.6 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME88956.1 - 0.013 15.8 3.1 0.013 15.8 2.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EME88956.1 - 0.62 10.3 16.5 0.34 11.2 3.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EME88956.1 - 2.5 8.5 19.5 1.3 9.4 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF3778 PF12620.3 EME88957.1 - 0.17 11.4 1.8 0.46 10.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) SUZ-C PF12901.2 EME88958.1 - 0.00014 21.3 1.8 0.00042 19.8 1.3 1.8 1 0 0 1 1 1 1 SUZ-C motif MRP-S31 PF15433.1 EME88958.1 - 0.082 12.3 6.5 0.11 11.8 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Selenoprotein_S PF06936.6 EME88958.1 - 0.15 11.5 8.9 0.34 10.4 6.2 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) U1snRNP70_N PF12220.3 EME88958.1 - 8.3 6.8 12.2 6.7 7.1 3.0 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HLH PF00010.21 EME88960.1 - 5.9e-15 54.6 0.6 1.1e-14 53.8 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CN_hydrolase PF00795.17 EME88961.1 - 9.1e-28 96.8 0.0 8.4e-27 93.7 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase SBP56 PF05694.6 EME88962.1 - 1.3e-05 23.9 0.0 0.0062 15.0 0.0 2.8 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 EME88962.1 - 0.039 13.0 0.0 7.3 5.5 0.0 2.7 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 EME88962.1 - 0.083 11.7 0.0 32 3.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Nup160 PF11715.3 EME88962.1 - 0.17 9.9 0.0 0.28 9.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cupin_1 PF00190.17 EME88963.1 - 1.2e-25 89.6 0.3 1.2e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EME88963.1 - 2.5e-22 78.1 0.6 2e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EME88963.1 - 2e-09 36.6 0.1 0.00033 19.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EME88963.1 - 0.0028 17.3 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EME88963.1 - 0.0032 17.1 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Cupin 2OG-FeII_Oxy_5 PF13759.1 EME88963.1 - 0.0072 16.6 0.3 42 4.5 0.0 3.8 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase FdtA PF05523.6 EME88963.1 - 0.0086 15.5 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 1 WxcM-like, C-terminal DHO_dh PF01180.16 EME88964.1 - 2.4e-20 72.7 0.1 2.9e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 EME88964.1 - 0.57 9.2 7.7 0.8 8.7 5.3 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase T2SF PF00482.18 EME88965.1 - 0.0015 18.4 0.2 0.0034 17.2 0.2 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DUF607 PF04678.8 EME88965.1 - 1 9.2 13.0 6.5 6.6 7.4 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Synaptobrevin PF00957.16 EME88965.1 - 1.2 8.8 5.7 0.34 10.5 0.4 2.4 2 1 0 2 2 2 0 Synaptobrevin DUF3899 PF13038.1 EME88965.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) LMBR1 PF04791.11 EME88965.1 - 1.3 7.5 6.7 4.5 5.7 4.6 1.9 1 1 0 1 1 1 0 LMBR1-like membrane protein 4HBT PF03061.17 EME88966.1 - 2.4e-08 33.9 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily UQ_con PF00179.21 EME88967.1 - 3.3e-19 68.7 0.0 3.6e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EME88967.1 - 0.0017 18.1 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Trs65 PF12735.2 EME88968.1 - 1.9e-35 122.6 1.3 2.2e-35 122.4 0.2 1.5 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Mob1_phocein PF03637.12 EME88969.1 - 1.9e-33 115.5 0.9 2.3e-17 63.1 0.1 2.2 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 EME88970.1 - 5.4e-30 104.3 0.0 1.2e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Leo1-like protein Glyco_hydro_3 PF00933.16 EME88971.1 - 5.1e-87 291.6 0.0 8.7e-87 290.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME88971.1 - 5.3e-38 130.8 0.0 4e-37 127.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME88971.1 - 1.5e-17 63.3 0.0 3.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4243 PF14027.1 EME88972.1 - 1.8e-71 241.2 3.6 4.3e-71 240.0 2.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) Imm31 PF15595.1 EME88972.1 - 0.02 14.6 0.1 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 31 Adaptin_N PF01602.15 EME88975.1 - 8.3e-95 318.0 8.4 1.3e-94 317.4 5.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EME88975.1 - 1.2e-60 202.9 0.0 3.6e-60 201.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EME88975.1 - 1.9e-60 202.5 0.5 4.8e-60 201.3 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EME88975.1 - 1.7e-14 53.8 2.3 1e-06 28.9 0.0 4.0 1 1 2 3 3 3 3 HEAT repeats Cnd1 PF12717.2 EME88975.1 - 1e-06 28.6 5.8 0.0031 17.4 0.0 3.7 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EME88975.1 - 3.5e-05 23.5 0.2 0.27 11.4 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EME88975.1 - 0.0084 16.5 2.5 1.2 9.7 0.0 4.2 3 1 1 4 4 4 2 HEAT-like repeat Mago_nashi PF02792.9 EME88976.1 - 5.5e-77 256.3 0.3 6.4e-77 256.1 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Phage_portal_2 PF05136.8 EME88976.1 - 0.07 11.6 0.0 0.087 11.3 0.0 1.0 1 0 0 1 1 1 0 Phage portal protein, lambda family Vac_ImportDeg PF09783.4 EME88977.1 - 1.4e-67 226.5 0.1 1.6e-67 226.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF2790 PF10976.3 EME88978.1 - 0.093 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) DUF4345 PF14248.1 EME88978.1 - 0.22 10.9 3.6 0.15 11.4 1.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) Peptidase_M49 PF03571.10 EME88979.1 - 1.2e-214 713.5 0.0 1.4e-214 713.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 DUF814 PF05670.8 EME88980.1 - 1.5e-21 76.0 0.0 3.9e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) CENP-H PF05837.7 EME88980.1 - 0.051 13.7 7.4 0.088 12.9 5.2 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Sec62 PF03839.11 EME88980.1 - 5.9 6.2 11.0 8.1 5.7 7.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 adh_short PF00106.20 EME88981.1 - 2.7e-26 92.4 0.0 3.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME88981.1 - 5.5e-13 48.9 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME88981.1 - 2.8e-07 30.5 0.0 5.9e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME88981.1 - 1.3e-06 28.5 0.2 2.6e-05 24.2 0.2 2.3 2 1 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 EME88981.1 - 5.2e-06 26.2 0.6 8.8e-06 25.4 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EME88981.1 - 7.1e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EME88981.1 - 0.00059 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EME88981.1 - 0.0014 19.0 0.4 0.003 17.9 0.3 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EME88981.1 - 0.0038 17.2 0.1 0.0084 16.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EME88981.1 - 0.0072 16.5 0.5 0.014 15.6 0.3 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EME88981.1 - 0.0092 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EME88981.1 - 0.011 15.6 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amidase_3 PF01520.13 EME88981.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase NAD_Gly3P_dh_N PF01210.18 EME88981.1 - 0.033 13.9 0.5 0.09 12.5 0.1 1.9 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Helicase_RecD PF05127.9 EME88981.1 - 0.035 13.7 0.1 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase Oxidored_nitro PF00148.14 EME88981.1 - 0.036 12.6 0.0 0.076 11.6 0.0 1.5 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Polysacc_synt_2 PF02719.10 EME88981.1 - 0.058 12.2 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mannitol_dh PF01232.18 EME88981.1 - 0.11 12.4 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain PTCB-BRCT PF12738.2 EME88982.1 - 2.2e-28 97.8 6.4 8.1e-22 76.8 0.1 4.8 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 EME88982.1 - 1e-27 96.0 0.0 5.3e-10 39.3 0.0 6.7 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PBP1_TM PF14812.1 EME88982.1 - 3.5 8.0 7.1 20 5.5 0.5 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RWD PF05773.17 EME88983.1 - 1.7e-25 89.0 1.7 3.3e-25 88.1 1.2 1.5 1 0 0 1 1 1 1 RWD domain Myb_DNA-bind_2 PF08914.6 EME88983.1 - 0.19 11.5 1.7 0.42 10.4 0.3 2.1 2 0 0 2 2 2 0 Rap1 Myb domain DBINO PF13892.1 EME88983.1 - 0.87 9.6 15.3 1.8 8.6 10.6 1.5 1 0 0 1 1 1 0 DNA-binding domain TPR_19 PF14559.1 EME88984.1 - 3.7e-08 33.5 8.2 0.011 16.0 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EME88984.1 - 4.4e-08 32.4 0.1 0.00062 19.4 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EME88984.1 - 6.9e-08 32.4 5.0 0.36 11.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EME88984.1 - 1.4e-07 31.3 2.5 0.026 14.4 0.0 3.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EME88984.1 - 8e-07 28.6 0.1 0.0027 17.3 0.0 3.3 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EME88984.1 - 1.3e-06 28.8 4.5 0.11 13.1 0.1 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EME88984.1 - 4.2e-05 23.0 0.1 0.88 9.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EME88984.1 - 4.4e-05 23.5 1.2 0.26 11.4 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EME88984.1 - 0.00029 20.2 0.0 0.04 13.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME88984.1 - 0.0003 20.3 0.0 0.01 15.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME88984.1 - 0.035 13.9 3.5 4.9 7.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EME88984.1 - 0.16 12.0 6.2 7.4 6.7 0.1 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Alb1 PF09135.6 EME88984.1 - 0.28 11.8 4.0 0.87 10.2 2.8 1.8 1 0 0 1 1 1 0 Alb1 TPR_6 PF13174.1 EME88984.1 - 0.29 11.6 6.6 10 6.8 0.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF3571 PF12095.3 EME88984.1 - 1.2 9.4 4.7 2.1 8.6 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) SHNi-TPR PF10516.4 EME88984.1 - 4.2 6.6 7.5 9.9 5.4 0.0 3.5 3 1 0 3 3 3 0 SHNi-TPR HMG_box PF00505.14 EME88985.1 - 1.2e-08 35.1 2.6 1.3e-08 34.9 1.8 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box PRTase_2 PF15609.1 EME88985.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF1690 PF07956.6 EME88986.1 - 1.3e-26 93.2 12.5 1.4e-14 54.3 3.8 2.1 1 1 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.1 EME88986.1 - 0.0088 16.0 2.1 0.0088 16.0 1.4 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion Tup_N PF08581.5 EME88986.1 - 0.41 10.8 3.8 11 6.2 0.2 3.0 3 0 0 3 3 3 0 Tup N-terminal Acetyltransf_1 PF00583.19 EME88987.1 - 4.6e-12 45.7 0.0 7.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME88987.1 - 1.5e-07 31.4 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME88987.1 - 0.00024 21.2 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EME88987.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME88987.1 - 0.0047 16.6 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EME88987.1 - 0.05 13.7 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.15 EME88988.1 - 6.3e-63 211.8 2.2 1.7e-62 210.5 1.5 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EME88988.1 - 3.3e-32 112.6 0.0 3.1e-30 106.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EME88988.1 - 1.6e-31 109.2 7.6 1.6e-31 109.2 5.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.2 EME88988.1 - 4.1e-17 62.9 0.0 1.1e-16 61.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EME88988.1 - 7.1e-16 57.4 0.0 1.9e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EME88988.1 - 1.1e-15 57.2 0.0 2.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME88988.1 - 5.2e-05 22.9 1.5 0.00019 21.0 0.2 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SieB PF14163.1 EME88988.1 - 0.015 14.8 0.5 0.063 12.8 0.3 2.1 1 0 0 1 1 1 0 Superinfection exclusion protein B Glutaredoxin PF00462.19 EME88989.1 - 1.2e-19 70.0 0.0 1.7e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EME88989.1 - 0.0069 16.1 0.0 0.01 15.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 EME88989.1 - 0.0088 16.2 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EME88989.1 - 0.013 15.7 0.1 0.026 14.7 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain HGD-D PF06050.8 EME88989.1 - 0.013 14.3 0.0 0.013 14.3 0.0 1.0 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DSBA PF01323.15 EME88989.1 - 0.12 11.9 0.2 0.71 9.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_3 PF13417.1 EME88989.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Zn_ribbon_2 PF12674.2 EME88989.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF1857 PF08982.6 EME88990.1 - 6e-39 133.0 0.0 6.7e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF2498 PF10692.4 EME88990.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Cu-oxidase_3 PF07732.10 EME88991.1 - 2.3e-41 140.2 2.7 8.2e-41 138.4 0.4 2.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME88991.1 - 5.2e-36 123.2 5.7 1.9e-32 111.6 0.0 3.6 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EME88991.1 - 3e-30 105.2 0.0 6.3e-30 104.1 0.0 1.6 2 0 0 2 2 2 1 Multicopper oxidase Glu-tRNAGln PF02686.10 EME88991.1 - 0.13 12.0 0.2 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Phosphoesterase PF04185.9 EME88992.1 - 1.1e-34 120.2 3.3 1.8e-34 119.5 2.0 1.5 1 1 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 EME88993.1 - 3.9e-57 193.1 3.3 4.4e-57 193.0 2.3 1.0 1 0 0 1 1 1 1 VIT family M11L PF11099.3 EME88993.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 1 0 1 1 1 0 Apoptosis regulator M11L like Mannosyl_trans PF05007.8 EME88994.1 - 2e-76 257.0 14.4 3.2e-76 256.4 10.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EME88994.1 - 1.3e-09 37.3 13.7 1.2e-08 34.2 9.5 2.1 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EME88994.1 - 3.7e-05 23.3 21.3 3.7e-05 23.3 14.8 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) HPD PF05044.7 EME88994.1 - 0.073 12.7 0.3 0.16 11.5 0.2 1.5 2 0 0 2 2 2 0 Homeo-prospero domain AhpC-TSA PF00578.16 EME88995.1 - 5.3e-28 97.1 0.0 6.8e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EME88995.1 - 1.8e-12 47.0 0.0 2.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin MARVEL PF01284.18 EME88996.1 - 0.039 13.7 18.0 0.05 13.4 12.5 1.1 1 0 0 1 1 1 0 Membrane-associating domain Steroid_dh PF02544.11 EME88996.1 - 0.079 12.7 4.1 0.35 10.6 0.3 2.2 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Amastin PF07344.6 EME88996.1 - 1.5 8.4 9.4 2.1 7.9 6.0 1.6 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF1673 PF07895.6 EME88996.1 - 6.3 6.2 7.4 1.2 8.6 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) DUF3290 PF11694.3 EME88996.1 - 6.9 6.3 6.3 1.8 8.2 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF1823 PF08853.6 EME88998.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) p450 PF00067.17 EME88999.1 - 1.6e-05 23.6 0.0 2.6e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EME89002.1 - 7.3e-66 221.9 0.0 1.1e-65 221.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89002.1 - 2e-46 158.1 0.0 3.1e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EME89002.1 - 6.9e-27 93.4 0.0 1.5e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EME89002.1 - 5e-17 61.5 0.1 1.1e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EME89002.1 - 2.1e-16 59.8 0.1 5.6e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EME89002.1 - 2.1e-07 30.1 0.0 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EME89002.1 - 0.0017 18.7 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Seadorna_VP7 PF07387.6 EME89002.1 - 0.007 15.2 0.1 0.017 13.9 0.0 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 DUF1777 PF08648.7 EME89003.1 - 0.00082 19.1 11.6 0.00082 19.1 8.0 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1777) GMC_oxred_N PF00732.14 EME89005.1 - 9.3e-63 212.1 0.0 1.3e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EME89005.1 - 1.7e-29 102.9 0.0 3.2e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EME89005.1 - 5.3e-07 28.8 0.0 0.0013 17.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME89005.1 - 1.5e-05 24.0 0.0 0.0016 17.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EME89005.1 - 0.00093 19.1 0.1 0.0026 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EME89005.1 - 0.0022 16.9 0.0 0.0046 15.9 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME89005.1 - 0.0052 16.6 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME89005.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EME89005.1 - 0.042 13.9 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME89005.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EME89005.1 - 0.13 10.6 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EME89005.1 - 0.26 10.1 0.0 15 4.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.27 EME89006.1 - 1.2e-13 50.3 5.0 1.5e-05 24.6 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PPTA PF01239.17 EME89008.1 - 1.6e-37 125.2 15.7 2.2e-07 29.9 0.0 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF2522 PF10747.4 EME89008.1 - 0.0023 17.9 0.2 0.0086 16.1 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2522) PLDc_2 PF13091.1 EME89009.1 - 1.6e-21 76.3 0.0 2.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EME89009.1 - 0.0017 18.0 0.1 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EME89009.1 - 0.13 11.2 0.0 0.99 8.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Piwi PF02171.12 EME89010.1 - 0.07 12.0 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Piwi domain Pribosyl_synth PF14572.1 EME89011.1 - 3.1e-44 150.9 1.4 6.5e-39 133.5 0.8 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EME89011.1 - 3.2e-43 146.1 0.5 6.2e-42 142.0 0.0 2.5 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EME89011.1 - 9.5e-13 47.9 0.5 1.5e-11 44.0 0.3 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EME89011.1 - 8.9e-05 21.7 0.2 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PA PF02225.17 EME89011.1 - 0.17 11.5 1.4 0.38 10.4 1.0 1.7 1 1 0 1 1 1 0 PA domain Ribosomal_S6e PF01092.14 EME89012.1 - 3.8e-63 210.8 0.2 8.4e-63 209.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Spt5_N PF11942.3 EME89012.1 - 8.9 7.0 6.9 2.6 8.7 2.7 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Alpha-L-AF_C PF06964.7 EME89013.1 - 3.1e-34 118.2 0.3 4.9e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 EME89014.1 - 2.5e-101 339.5 22.2 2.8e-101 339.3 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME89014.1 - 3.4e-30 104.9 31.9 1.7e-26 92.7 9.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1689 PF07954.6 EME89014.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Lig_chan PF00060.21 EME89014.1 - 0.41 10.3 5.3 1.4 8.5 0.0 2.8 2 1 0 2 2 2 0 Ligand-gated ion channel Tmemb_18A PF09771.4 EME89014.1 - 0.65 9.9 2.5 1.8 8.5 0.1 2.9 3 1 1 4 4 4 0 Transmembrane protein 188 Ribonuc_L-PSP PF01042.16 EME89015.1 - 0.0015 18.3 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3295 PF11702.3 EME89018.1 - 2.8e-125 419.2 41.1 2.8e-125 419.2 28.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EME89018.1 - 1e-10 40.9 3.1 1.9e-10 40.1 2.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) NOA36 PF06524.7 EME89018.1 - 0.89 8.7 7.2 1.4 8.1 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Gag_p24 PF00607.15 EME89021.1 - 0.016 14.7 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) SEN1_N PF12726.2 EME89025.1 - 1.5e-136 456.4 0.0 1.9e-136 456.0 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EME89025.1 - 8.8e-70 234.9 1.3 8.8e-70 234.9 0.9 2.5 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EME89025.1 - 1.1e-60 204.4 0.0 2.6e-60 203.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME89025.1 - 1.5e-10 40.6 0.2 6.3e-10 38.6 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 EME89025.1 - 2.2e-05 24.0 1.1 0.0038 16.7 0.0 3.2 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EME89025.1 - 0.00021 20.8 0.1 0.00077 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain Viral_helicase1 PF01443.13 EME89025.1 - 0.00027 20.5 0.0 0.8 9.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EME89025.1 - 0.0057 17.0 0.1 0.0057 17.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME89025.1 - 0.033 14.3 0.1 0.45 10.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EME89025.1 - 0.054 12.8 1.2 0.36 10.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain PPP1R35_C PF15503.1 EME89026.1 - 0.051 13.0 0.4 0.12 11.9 0.3 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus DAO PF01266.19 EME89027.1 - 4e-35 121.3 0.0 4.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME89027.1 - 4.2e-05 23.4 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EME89027.1 - 0.0005 19.0 0.1 0.13 11.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EME89027.1 - 0.0049 16.6 0.1 1 9.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EME89027.1 - 0.026 13.4 0.0 0.45 9.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EME89027.1 - 0.1 12.4 0.2 0.57 10.0 0.0 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME89027.1 - 0.11 10.9 0.1 10 4.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EME89027.1 - 0.12 12.8 1.1 21 5.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EME89027.1 - 0.15 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family MIP PF00230.15 EME89028.1 - 3.2e-49 167.4 19.3 4.2e-49 167.0 13.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Herpes_LMP2 PF07415.6 EME89029.1 - 2.3 6.7 4.0 2.5 6.5 2.8 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF605 PF04652.11 EME89030.1 - 4.8 6.4 9.2 5.2 6.3 6.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF2264 PF10022.4 EME89031.1 - 3.8e-127 423.8 0.6 4.7e-127 423.5 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BNR PF02012.15 EME89031.1 - 0.048 13.4 0.2 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_18 PF00704.23 EME89032.1 - 6.6e-11 42.2 0.0 1.8e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 FAD_binding_3 PF01494.14 EME89033.1 - 7.7e-13 48.2 0.0 1.8e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EME89033.1 - 8.9e-05 22.4 0.0 0.00031 20.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME89033.1 - 0.00068 18.6 0.1 0.0037 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME89033.1 - 0.007 16.7 0.9 0.89 9.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EME89033.1 - 0.0072 15.0 0.6 0.086 11.4 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EME89033.1 - 0.017 14.8 0.1 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EME89033.1 - 0.042 13.7 0.1 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.2 EME89034.1 - 0.044 14.1 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain IN_DBD_C PF00552.16 EME89034.1 - 0.076 12.4 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Integrase DNA binding domain Pkinase PF00069.20 EME89035.1 - 1.6e-07 30.7 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ran-binding PF05508.6 EME89036.1 - 3.3e-110 367.7 0.0 4.2e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein ORC6 PF05460.8 EME89036.1 - 0.00027 20.1 2.5 0.16 11.0 0.9 2.2 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) DegQ PF08181.6 EME89036.1 - 0.07 12.8 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 DegQ (SacQ) family His_Phos_1 PF00300.17 EME89037.1 - 8.8e-20 71.3 1.2 9.8e-20 71.2 0.1 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) GTP_EFTU PF00009.22 EME89038.1 - 2.7e-44 150.8 0.0 4.4e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME89038.1 - 1.6e-20 73.1 0.0 3.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EME89038.1 - 0.00078 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EME89038.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.15 EME89038.1 - 0.12 11.0 4.7 0.31 9.6 3.2 1.7 1 1 0 1 1 1 0 G-protein alpha subunit Rad4 PF03835.10 EME89039.1 - 4.2e-36 123.5 1.0 9e-36 122.4 0.7 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EME89039.1 - 1e-26 92.4 0.0 2.1e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EME89039.1 - 1.6e-17 62.7 0.0 3.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EME89039.1 - 1.2e-15 57.5 0.1 3.3e-15 56.1 0.1 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EME89039.1 - 0.0033 17.5 0.0 0.015 15.5 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily Pkinase PF00069.20 EME89040.1 - 2.7e-69 233.2 0.0 3.3e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89040.1 - 1.1e-30 106.5 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME89040.1 - 0.0033 16.4 0.0 0.006 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME89040.1 - 0.0095 15.6 0.0 0.021 14.5 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EME89040.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Aldose_epim PF01263.15 EME89041.1 - 9.6e-43 146.3 0.0 1.1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FLgD_tudor PF13861.1 EME89041.1 - 0.032 14.2 0.2 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 FlgD Tudor-like domain Pox_A6 PF04924.7 EME89041.1 - 0.081 11.7 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A6 protein Rif1_N PF12231.3 EME89042.1 - 5.5e-94 315.1 2.8 7.4e-94 314.7 1.9 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal HEAT_2 PF13646.1 EME89042.1 - 0.0024 18.0 0.0 2.5 8.4 0.0 4.1 2 1 1 3 3 3 1 HEAT repeats DUF2454 PF10521.4 EME89042.1 - 0.004 16.2 0.0 0.0085 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF4129 PF13559.1 EME89042.1 - 0.13 12.2 0.7 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Ric8 PF10165.4 EME89043.1 - 1.4e-121 406.4 0.0 1.6e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Aldedh PF00171.17 EME89043.1 - 0.044 12.1 0.0 0.069 11.4 0.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family adh_short PF00106.20 EME89044.1 - 2.3e-29 102.4 2.6 3.2e-29 102.0 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89044.1 - 5.2e-28 98.4 0.1 6.6e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME89044.1 - 1.7e-16 60.3 0.8 2.7e-16 59.7 0.6 1.2 1 0 0 1 1 1 1 KR domain But2 PF09792.4 EME89045.1 - 4.2e-27 94.6 0.0 4.7e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain TraP PF07296.6 EME89046.1 - 0.097 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 TraP protein FUSC_2 PF13515.1 EME89046.1 - 0.3 11.0 13.9 0.11 12.4 1.4 2.8 1 1 2 3 3 3 0 Fusaric acid resistance protein-like TRI12 PF06609.8 EME89047.1 - 5.9e-61 206.4 26.3 7.6e-61 206.0 18.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME89047.1 - 3.9e-19 68.5 42.9 7.8e-18 64.3 28.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily UPF0220 PF05255.6 EME89047.1 - 1.1 8.4 9.6 0.16 11.1 0.2 3.5 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0220) Glyco_trans_2_3 PF13632.1 EME89047.1 - 1.2 8.7 0.0 1.2 8.7 0.0 3.4 3 1 0 3 3 3 0 Glycosyl transferase family group 2 Gln-synt_C PF00120.19 EME89048.1 - 4.7e-61 206.2 0.0 6e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EME89049.1 - 1.6e-25 89.9 1.5 2.2e-25 89.4 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89049.1 - 1.7e-16 60.7 0.0 2.1e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME89049.1 - 5.1e-07 29.5 1.1 9.1e-07 28.7 0.7 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EME89049.1 - 0.00011 21.9 0.2 0.00022 20.9 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EME89049.1 - 0.0016 17.9 0.1 0.0025 17.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 EME89049.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 EME89049.1 - 0.021 14.8 1.7 0.06 13.3 0.9 1.9 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 EME89049.1 - 0.05 14.1 0.0 0.25 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EME89049.1 - 0.09 12.5 0.5 1 9.2 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EME89049.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_2 PF02230.11 EME89050.1 - 2.8e-60 203.4 0.0 3.2e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EME89050.1 - 3.1e-08 33.5 0.0 6.8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME89050.1 - 7.4e-07 28.6 0.1 0.00011 21.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EME89050.1 - 7.8e-06 25.9 0.5 0.01 15.6 0.0 2.7 1 1 2 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EME89050.1 - 1.2e-05 24.9 0.0 0.073 12.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 EME89050.1 - 0.0046 16.4 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 EME89050.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) FSH1 PF03959.8 EME89050.1 - 0.0077 15.6 0.1 0.041 13.3 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EME89050.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EME89050.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.9 EME89050.1 - 0.027 13.6 0.3 1.6 7.9 0.0 2.5 2 1 1 3 3 3 0 Secretory lipase HEM4 PF02602.10 EME89050.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Cutinase PF01083.17 EME89050.1 - 0.036 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase LigB PF02900.13 EME89051.1 - 3.9e-46 157.2 0.0 4.4e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PrpR_N PF06506.6 EME89051.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator L51_S25_CI-B8 PF05047.11 EME89052.1 - 6.3e-16 57.8 0.0 7.9e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EME89053.1 - 4e-42 142.9 0.0 7e-42 142.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MT0933_antitox PF14013.1 EME89053.1 - 0.0051 16.8 1.7 0.0099 15.9 1.2 1.4 1 0 0 1 1 1 1 MT0933-like antitoxin protein Synaptobrevin PF00957.16 EME89054.1 - 5.2e-31 106.1 1.4 5.9e-31 105.9 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 EME89054.1 - 0.0014 18.2 0.1 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral envelope protein EMP24_GP25L PF01105.19 EME89054.1 - 0.0093 15.6 0.2 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sec20 PF03908.8 EME89054.1 - 0.033 13.8 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Sec20 Fzo_mitofusin PF04799.8 EME89054.1 - 0.037 13.4 0.6 0.037 13.4 0.4 1.4 1 1 1 2 2 2 0 fzo-like conserved region DUF2951 PF11166.3 EME89054.1 - 0.071 12.9 0.3 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) NPV_P10 PF05531.7 EME89054.1 - 0.096 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF515 PF04415.7 EME89054.1 - 0.13 10.4 0.1 0.15 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SnoaL_4 PF13577.1 EME89055.1 - 0.00071 19.4 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain Cation_efflux PF01545.16 EME89056.1 - 1.8e-49 168.3 1.0 2.3e-49 168.0 0.7 1.1 1 0 0 1 1 1 1 Cation efflux family SelP_N PF04592.9 EME89056.1 - 7.6 5.8 9.2 0.4 10.0 0.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Myb_DNA-bind_6 PF13921.1 EME89057.1 - 1e-06 28.7 0.8 5.4e-06 26.4 0.1 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EME89057.1 - 0.038 14.0 0.5 0.27 11.3 0.1 2.6 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EME89058.1 - 0.028 14.5 0.3 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Transferase PF02458.10 EME89059.1 - 5.2e-27 94.3 0.0 6e-22 77.6 0.0 2.8 2 1 0 2 2 2 2 Transferase family ANTH PF07651.11 EME89060.1 - 5.1e-61 205.8 0.5 6.5e-61 205.4 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EME89060.1 - 3.6e-05 23.6 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EME89060.1 - 0.00091 19.2 17.7 0.00091 19.2 12.3 4.9 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) RepA_C PF04796.7 EME89060.1 - 0.0086 15.7 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 Plasmid encoded RepA protein Sugar_tr PF00083.19 EME89061.1 - 3.6e-81 273.0 15.0 4e-81 272.8 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME89061.1 - 1.7e-22 79.6 34.0 9.5e-16 57.4 7.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EME89061.1 - 1.8e-05 23.3 1.9 1.8e-05 23.3 1.3 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein NmrA PF05368.8 EME89062.1 - 3.8e-47 160.5 0.0 4.4e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EME89062.1 - 3.1e-12 46.8 0.0 4.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME89062.1 - 8.8e-05 21.3 0.0 0.00012 20.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0261 PF06792.6 EME89063.1 - 1.5e-146 488.0 0.1 1.6e-146 487.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 EME89064.1 - 1.2e-133 444.2 0.6 1.3e-133 444.0 0.4 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EME89064.1 - 3.1e-07 29.8 0.2 5.5e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EME89064.1 - 0.75 8.9 3.3 4.3 6.5 0.1 2.7 2 1 1 3 3 3 0 PcrB family Glyco_transf_90 PF05686.7 EME89067.1 - 5.9e-14 51.5 6.1 3.8e-13 48.8 4.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 90 Med10 PF09748.4 EME89068.1 - 1e-32 112.6 0.7 1.2e-32 112.4 0.5 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EME89068.1 - 0.00051 19.6 0.1 0.00062 19.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) Mei4 PF13971.1 EME89068.1 - 0.027 13.4 0.2 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 DNA_repr_REX1B PF14966.1 EME89068.1 - 0.055 13.8 0.4 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 DNA repair REX1-B NAAA-beta PF15508.1 EME89068.1 - 0.063 13.6 0.1 1.2 9.5 0.0 2.3 1 1 1 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PAH PF02671.16 EME89068.1 - 0.094 12.3 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Paired amphipathic helix repeat Flagellin_N PF00669.15 EME89068.1 - 0.2 11.4 1.9 0.35 10.6 1.3 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region PXA PF02194.10 EME89069.1 - 4.8e-35 120.8 0.0 7.4e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.11 EME89071.1 - 3e-12 46.1 0.1 5.4e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EME89071.1 - 6.9e-06 25.3 0.1 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EME89071.1 - 0.025 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.1 EME89071.1 - 0.055 13.6 0.5 0.18 11.9 0.2 1.9 1 1 1 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.1 EME89071.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 EME89071.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.11 EME89071.1 - 0.12 12.0 0.1 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_38 PF13936.1 EME89071.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CDO_I PF05995.7 EME89073.1 - 1e-37 128.9 0.1 1.3e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EME89073.1 - 3.4e-06 26.5 0.0 4.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 EME89074.1 - 4.9e-20 71.1 0.1 1.1e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EME89074.1 - 2e-18 66.4 0.1 4.4e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EME89074.1 - 1.7e-09 37.1 0.1 1.2e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EME89074.1 - 3.7e-05 23.2 0.1 0.55 9.6 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EME89074.1 - 0.00034 20.4 0.2 0.061 13.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EME89074.1 - 0.0045 15.8 0.8 0.015 14.0 0.1 2.0 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EME89074.1 - 0.018 15.5 0.0 0.067 13.6 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EME89074.1 - 0.099 12.5 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TRI12 PF06609.8 EME89075.1 - 8e-38 130.0 31.9 9.8e-38 129.7 22.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EME89075.1 - 4.3e-21 75.0 50.2 4.3e-21 75.0 34.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME89075.1 - 3.8e-10 38.9 14.0 3.8e-10 38.9 9.7 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter HSP9_HSP12 PF04119.7 EME89076.1 - 1.9e-16 59.9 7.6 1.9e-16 59.9 5.3 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 Tape_meas_lam_C PF09718.5 EME89076.1 - 0.047 13.6 2.1 0.047 13.6 1.5 2.7 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3602 PF12223.3 EME89076.1 - 0.071 13.4 7.2 0.14 12.5 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) DUF2413 PF10310.4 EME89076.1 - 0.17 10.6 9.9 0.21 10.3 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4594 PF15266.1 EME89076.1 - 1 9.4 5.4 2.2 8.3 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4594) Rotamase_3 PF13616.1 EME89076.1 - 1.7 8.9 6.5 2.4 8.4 4.5 1.4 1 1 0 1 1 1 0 PPIC-type PPIASE domain MT0933_antitox PF14013.1 EME89076.1 - 3.2 7.9 6.7 27 4.9 4.6 2.6 1 1 0 1 1 1 0 MT0933-like antitoxin protein Lyase_1 PF00206.15 EME89077.1 - 3.2e-114 381.3 0.0 6.4e-114 380.3 0.0 1.5 2 0 0 2 2 2 1 Lyase FumaraseC_C PF10415.4 EME89077.1 - 4.7e-22 77.8 0.0 1e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus DNA_primase_lrg PF04104.9 EME89078.1 - 5.6e-76 255.2 0.0 8.4e-76 254.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Asp PF00026.18 EME89079.1 - 6.2e-60 203.0 3.7 7.8e-60 202.7 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EME89079.1 - 0.038 14.5 5.2 0.15 12.5 0.4 3.4 3 2 1 4 4 4 0 Aspartyl protease Phage_Coat_B PF05356.6 EME89080.1 - 0.13 11.9 0.4 0.26 10.9 0.3 1.7 1 1 0 1 1 1 0 Phage Coat protein B Abhydrolase_6 PF12697.2 EME89081.1 - 7.9e-13 48.8 0.4 1.6e-12 47.8 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME89081.1 - 3.6e-11 43.0 0.0 5.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EME89081.1 - 5.9e-05 22.7 0.0 7.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EME89081.1 - 0.00019 21.0 0.0 0.00049 19.7 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EME89081.1 - 0.00076 19.2 0.1 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EME89081.1 - 0.025 13.8 0.0 6.9 5.8 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family CortBP2 PF09727.4 EME89082.1 - 0.0075 15.7 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Cortactin-binding protein-2 DUF4175 PF13779.1 EME89082.1 - 0.014 13.0 3.1 0.021 12.5 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) MFS_1 PF07690.11 EME89084.1 - 3.9e-45 154.0 49.9 1.4e-44 152.2 34.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME89084.1 - 3.4e-09 35.8 13.4 3.4e-09 35.8 9.3 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter Ribosomal_L36 PF00444.13 EME89085.1 - 3e-17 62.3 12.0 4.1e-17 61.8 8.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_S17 PF00366.15 EME89086.1 - 7.5e-30 102.7 0.5 1.1e-29 102.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1748 PF08520.5 EME89087.1 - 1.3e-32 111.2 0.0 1.4e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) NGP1NT PF08153.7 EME89089.1 - 3e-47 159.8 0.8 3e-47 159.8 0.6 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EME89089.1 - 8.8e-18 64.3 0.0 6.1e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.16 EME89089.1 - 7.4e-05 22.0 0.0 0.031 13.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 EME89089.1 - 0.00087 18.5 0.1 0.0031 16.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EME89089.1 - 0.0011 18.1 0.0 0.0022 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EME89089.1 - 0.0019 18.0 2.6 0.22 11.3 0.0 3.9 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 EME89089.1 - 0.003 17.0 0.1 0.63 9.4 0.0 3.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SusD-like_3 PF14322.1 EME89089.1 - 0.055 13.5 0.1 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Starch-binding associating with outer membrane UvrD_C PF13361.1 EME89090.1 - 5.1e-74 249.8 0.0 7.6e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EME89090.1 - 6.1e-58 196.5 10.5 1.6e-30 106.5 0.9 3.0 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EME89090.1 - 1.1e-13 51.2 0.0 3.8e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EME89090.1 - 1.3e-12 47.2 0.6 9.2e-12 44.5 0.4 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EME89090.1 - 1.2e-06 28.2 3.0 8.7e-05 22.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EME89090.1 - 1.5e-05 24.6 0.3 0.21 11.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EME89090.1 - 0.00082 19.0 0.5 0.00082 19.0 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EME89090.1 - 0.033 14.3 0.8 1.9 8.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain SMC_Nse1 PF07574.8 EME89090.1 - 0.051 13.2 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Nse1 non-SMC component of SMC5-6 complex Helicase_RecD PF05127.9 EME89090.1 - 0.16 11.6 3.5 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Helicase AAA_16 PF13191.1 EME89090.1 - 0.29 11.1 4.3 0.91 9.4 0.3 2.9 2 1 0 2 2 2 0 AAA ATPase domain UCH PF00443.24 EME89091.1 - 7e-22 77.8 1.0 4.1e-21 75.3 0.7 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EME89091.1 - 2.5e-05 23.7 0.9 2.5e-05 23.7 0.6 2.3 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase FKBP_C PF00254.23 EME89092.1 - 1.7e-32 111.2 0.1 2.1e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box-like_2 PF13013.1 EME89093.1 - 0.0089 15.7 0.3 0.017 14.8 0.2 1.5 1 1 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 EME89093.1 - 0.025 14.3 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 F-box-like DUF2281 PF10047.4 EME89093.1 - 0.13 12.5 0.2 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Ribosomal_L14e PF01929.12 EME89094.1 - 2e-24 85.7 0.3 2.9e-24 85.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EME89094.1 - 8.6e-05 22.1 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 KOW motif DUF1269 PF06897.7 EME89094.1 - 0.074 13.0 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) NAC PF01849.13 EME89095.1 - 1.7e-22 78.7 0.0 1.3e-21 75.8 0.0 2.3 2 0 0 2 2 2 1 NAC domain Mt_ATP-synt_D PF05873.7 EME89095.1 - 6.5e-19 68.1 1.4 1.2e-18 67.2 1.0 1.4 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) UBA PF00627.26 EME89095.1 - 0.00033 20.4 0.2 0.0028 17.4 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain IncA PF04156.9 EME89095.1 - 0.14 11.7 7.1 0.036 13.6 1.5 2.2 2 0 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EME89095.1 - 0.21 11.7 5.7 0.066 13.3 1.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EME89095.1 - 1.8 8.6 5.6 0.47 10.5 0.5 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF148 PF02520.12 EME89095.1 - 8.2 6.2 14.6 0.088 12.5 3.2 2.6 2 1 1 3 3 3 0 Domain of unknown function DUF148 zf-C2H2 PF00096.21 EME89096.1 - 1.7e-10 40.5 12.5 1.7e-05 24.8 1.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME89096.1 - 6.1e-08 32.5 14.5 2e-06 27.7 1.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME89096.1 - 1.8e-06 27.8 10.6 0.0037 17.4 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EME89096.1 - 0.00053 20.0 3.7 0.0094 16.0 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME89096.1 - 0.00058 19.9 2.7 0.0035 17.4 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EME89096.1 - 0.014 15.3 1.8 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 EME89096.1 - 0.066 13.1 0.6 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EME89096.1 - 0.17 11.5 0.4 0.17 11.5 0.3 2.7 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 EME89096.1 - 0.19 11.7 1.9 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 zinc-finger IBR PF01485.16 EME89096.1 - 0.23 11.3 3.3 1.9 8.4 0.2 2.2 1 1 1 2 2 2 0 IBR domain zf-BED PF02892.10 EME89096.1 - 0.74 9.6 10.1 7.5 6.3 1.0 2.8 1 1 2 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.2 EME89096.1 - 2.4 8.0 7.7 3.3 7.5 3.3 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 EME89096.1 - 3.3 7.9 6.4 4.7 7.4 2.7 2.0 1 1 1 2 2 2 0 CHY zinc finger zf-UBP PF02148.14 EME89097.1 - 0.017 15.2 0.3 0.028 14.5 0.2 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Amidohydro_4 PF13147.1 EME89098.1 - 1e-14 55.2 2.7 2.4e-08 34.3 0.1 3.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EME89098.1 - 4e-11 42.5 0.6 4.6e-08 32.7 0.2 3.0 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EME89098.1 - 1.9e-05 24.4 4.9 0.0074 15.9 0.9 4.0 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 EME89098.1 - 0.0021 17.3 0.6 0.1 11.7 0.0 3.0 3 1 1 4 4 4 1 Amidohydrolase family Xpo1 PF08389.7 EME89101.1 - 1.3e-31 109.5 3.2 6.1e-31 107.3 0.0 3.7 4 1 1 5 5 5 1 Exportin 1-like protein Cullin_binding PF03556.10 EME89101.1 - 0.062 13.4 0.1 0.38 10.9 0.0 2.4 1 0 0 1 1 1 0 Cullin binding DUF2115 PF09888.4 EME89101.1 - 0.24 11.4 0.2 1 9.4 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) FixQ PF05545.6 EME89102.1 - 0.017 14.7 0.0 0.067 12.8 0.0 2.1 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Baculo_11_kDa PF06143.6 EME89102.1 - 0.11 11.9 2.3 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF2721 PF11026.3 EME89102.1 - 7.7 6.1 10.9 3.7 7.1 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ARPC4 PF05856.7 EME89103.1 - 1.2e-75 252.5 3.0 1.4e-75 252.3 2.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3602 PF12223.3 EME89106.1 - 3.7e-11 43.2 11.0 1.7e-06 28.2 2.5 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Peptidase_M41 PF01434.13 EME89106.1 - 0.067 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 DUF998 PF06197.8 EME89107.1 - 0.035 13.4 0.2 0.043 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Phage_CRI PF05144.9 EME89108.1 - 0.06 12.4 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage replication protein CRI Yippee-Mis18 PF03226.9 EME89109.1 - 5e-23 80.9 0.9 5.7e-23 80.7 0.6 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EME89109.1 - 0.032 14.2 0.4 0.032 14.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-CHY PF05495.7 EME89109.1 - 0.051 13.7 0.6 6.8 6.9 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger Evr1_Alr PF04777.8 EME89109.1 - 0.16 11.9 0.9 0.81 9.6 0.1 2.0 1 1 1 2 2 2 0 Erv1 / Alr family KH_1 PF00013.24 EME89110.1 - 1.5e-39 133.4 8.7 1.6e-16 59.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EME89110.1 - 1.7e-30 104.1 12.4 1.9e-12 46.5 1.2 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EME89110.1 - 3.5e-11 42.4 8.6 0.0007 19.0 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EME89110.1 - 1.3e-07 31.0 5.5 0.067 12.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EME89110.1 - 0.00015 21.4 4.2 0.34 10.7 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EME89110.1 - 0.067 12.6 0.4 3.2 7.2 0.0 2.7 3 0 0 3 3 3 0 dUTPase Methyltransf_18 PF12847.2 EME89112.1 - 4.8e-16 59.3 0.0 7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME89112.1 - 6e-15 55.1 0.0 8.8e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME89112.1 - 1.2e-05 25.2 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME89112.1 - 2.1e-05 24.3 0.0 2.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME89112.1 - 2.8e-05 24.5 0.0 7e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME89112.1 - 0.0062 16.9 0.0 0.018 15.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EME89112.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EME89112.1 - 0.027 14.8 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.16 EME89113.1 - 2.5e-67 227.3 0.0 2.9e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EME89113.1 - 4.8e-05 22.5 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EME89113.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EME89113.1 - 0.00095 18.0 0.1 0.0023 16.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EME89113.1 - 0.0035 15.7 0.0 0.0055 15.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme T_hemolysin PF12261.3 EME89113.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin DUF3818 PF12825.2 EME89114.1 - 2.6e-40 138.1 2.2 2e-24 85.9 0.2 2.3 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EME89114.1 - 6.6e-25 87.3 0.0 1.5e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 PX-associated DUF3819 PF12842.2 EME89114.1 - 0.019 14.6 0.4 0.047 13.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF3482 PF11981.3 EME89114.1 - 4.4 6.4 8.8 20 4.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) BAF1_ABF1 PF04684.8 EME89115.1 - 0.72 8.6 5.5 0.97 8.2 3.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor F-box-like PF12937.2 EME89116.1 - 5.1e-11 42.1 1.9 7.3e-11 41.6 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EME89116.1 - 1.5e-08 34.0 3.8 0.15 11.6 0.1 5.8 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EME89116.1 - 1.7e-07 30.5 14.8 6.4 7.1 0.4 7.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 EME89116.1 - 0.00025 20.6 19.6 9.1 6.7 0.1 8.7 8 2 0 8 8 7 1 Leucine Rich Repeat F-box PF00646.28 EME89116.1 - 0.0068 16.0 0.4 0.0068 16.0 0.3 3.2 4 0 0 4 4 4 1 F-box domain CagZ PF09053.5 EME89116.1 - 0.057 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 CagZ Recep_L_domain PF01030.19 EME89116.1 - 0.061 13.3 1.4 1.4 8.8 0.1 3.3 2 2 1 3 3 3 0 Receptor L domain DUF1263 PF06882.7 EME89116.1 - 0.083 12.5 0.2 3 7.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1263) FTO_CTD PF12934.2 EME89116.1 - 0.11 12.0 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 FTO C-terminal domain Ste50p-SAM PF09235.5 EME89116.1 - 0.12 12.3 13.4 5.7 7.0 0.0 6.2 3 2 4 7 7 7 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EME89116.1 - 4.1 8.0 17.4 93 3.9 0.3 8.0 8 0 0 8 8 8 0 Leucine rich repeat Cellulase PF00150.13 EME89117.1 - 3.1e-07 29.8 0.0 6.8e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1028 PF06267.7 EME89120.1 - 0.022 14.2 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF1028) Lipase_GDSL_2 PF13472.1 EME89120.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Cytadhesin_P30 PF07271.6 EME89121.1 - 0.97 8.6 6.2 11 5.1 3.8 2.1 2 0 0 2 2 2 0 Cytadhesin P30/P32 Pkinase PF00069.20 EME89124.1 - 1.5e-60 204.5 0.0 1.8e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89124.1 - 1e-34 119.8 0.0 1.4e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME89124.1 - 5.8e-09 35.3 0.0 8.8e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EME89124.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Sugar_tr PF00083.19 EME89125.1 - 1.9e-98 329.9 27.1 2.8e-98 329.4 18.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME89125.1 - 7.6e-13 47.8 44.0 2.1e-12 46.4 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 EME89126.1 - 6.1e-62 209.2 0.0 9.2e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME89126.1 - 6.3e-40 137.0 0.0 9.6e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME89126.1 - 5.6e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3805 PF12712.2 EME89126.1 - 0.037 13.8 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3805) PEP-utilisers_N PF05524.8 EME89127.1 - 0.011 15.4 1.8 0.017 14.9 1.3 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Pfg27 PF09216.5 EME89127.1 - 0.074 12.6 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Pfg27 IncA PF04156.9 EME89127.1 - 0.089 12.3 4.0 0.11 12.1 2.8 1.1 1 0 0 1 1 1 0 IncA protein MerR-DNA-bind PF09278.6 EME89127.1 - 0.31 11.4 1.9 5.7 7.4 0.3 2.8 2 1 0 2 2 2 0 MerR, DNA binding CAP18_C PF12153.3 EME89127.1 - 1.9 8.2 4.9 0.25 11.0 0.5 1.7 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) APG6 PF04111.7 EME89127.1 - 3.8 6.4 7.1 4.6 6.2 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cyt-b5 PF00173.23 EME89128.1 - 8.1e-17 60.7 0.0 1.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF605 PF04652.11 EME89128.1 - 0.34 10.2 17.6 0.4 10.0 12.2 1.2 1 0 0 1 1 1 0 Vta1 like P12 PF12669.2 EME89129.1 - 0.25 11.5 2.5 0.44 10.7 1.7 1.6 1 1 0 1 1 1 0 Virus attachment protein p12 family Peptidase_M24 PF00557.19 EME89131.1 - 1.1e-45 155.7 0.0 1.3e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EME89131.1 - 0.0018 18.1 7.9 0.0018 18.1 5.5 2.3 2 0 0 2 2 2 1 MYND finger Urocanase PF01175.13 EME89131.1 - 0.11 10.5 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Urocanase DUF520 PF04461.8 EME89131.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF520) FAD_binding_3 PF01494.14 EME89132.1 - 5.9e-21 74.9 0.0 2.4e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EME89132.1 - 3.6e-05 22.7 0.0 0.00013 20.9 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EME89132.1 - 0.0009 19.2 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME89132.1 - 0.003 16.5 0.0 0.0051 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME89132.1 - 0.018 15.3 0.0 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME89132.1 - 0.028 14.2 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME89132.1 - 0.058 11.8 0.0 0.086 11.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EME89132.1 - 0.18 11.4 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF21 PF01595.15 EME89133.1 - 2.6e-32 111.5 0.2 4.1e-32 110.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EME89133.1 - 1.6e-07 31.0 0.1 0.027 14.2 0.1 3.1 3 0 0 3 3 3 2 CBS domain T4_Gp59_C PF08994.5 EME89133.1 - 0.22 11.7 0.0 0.48 10.6 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term DdrB PF12747.2 EME89134.1 - 0.11 12.2 0.1 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 DdrB-like protein adh_short PF00106.20 EME89135.1 - 1.5e-21 77.0 0.0 4.2e-21 75.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EME89135.1 - 1.2e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME89135.1 - 0.00013 22.0 0.0 0.00022 21.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EME89135.1 - 0.00014 21.7 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EME89135.1 - 0.0049 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EME89135.1 - 0.0097 15.0 0.0 3.5 6.6 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EME89135.1 - 0.025 14.0 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME89135.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Ank_2 PF12796.2 EME89136.1 - 4.4e-51 171.1 3.0 1.3e-16 60.7 0.0 4.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EME89136.1 - 1.8e-43 144.2 16.3 9.5e-06 25.1 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EME89136.1 - 5.8e-38 128.6 7.3 7.4e-11 42.2 0.4 6.9 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME89136.1 - 4.8e-34 115.6 12.5 3.7e-10 39.7 0.0 7.9 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME89136.1 - 5.6e-34 112.7 16.5 0.00038 20.4 0.0 10.3 10 1 0 10 10 10 8 Ankyrin repeat CorA PF01544.13 EME89136.1 - 1.3e-13 50.6 0.1 5.9e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Mob1_phocein PF03637.12 EME89137.1 - 9.6e-68 227.2 0.0 1.3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family NUDIX PF00293.23 EME89138.1 - 7.1e-15 54.8 0.4 9.2e-15 54.4 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain DUF2188 PF09954.4 EME89138.1 - 0.25 11.2 1.6 0.74 9.7 1.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) ATE_C PF04377.10 EME89140.1 - 2e-44 150.7 0.7 3.1e-44 150.1 0.5 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EME89140.1 - 3e-13 49.3 0.1 3e-13 49.3 0.1 2.1 3 0 0 3 3 3 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EME89140.1 - 0.023 14.6 0.5 0.043 13.7 0.3 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.17 EME89142.1 - 4.7e-63 213.3 0.0 9.2e-63 212.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SET PF00856.23 EME89143.1 - 9.2e-12 45.5 0.0 4.3e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF4451 PF14616.1 EME89144.1 - 1.4e-08 34.5 2.8 0.00016 21.4 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4451) Sugar_tr PF00083.19 EME89145.1 - 4.7e-85 285.8 29.6 5.5e-85 285.6 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME89145.1 - 6.2e-15 54.7 35.7 4.4e-10 38.8 7.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EME89145.1 - 0.0092 15.9 4.9 0.27 11.2 0.7 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1228) TPR_19 PF14559.1 EME89145.1 - 0.13 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase_6 PF13344.1 EME89146.1 - 1.6e-29 101.7 0.0 3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EME89146.1 - 2e-12 46.6 0.0 6.2e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EME89146.1 - 1.4e-11 45.2 0.0 1.1e-10 42.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EME89146.1 - 0.00012 22.4 0.2 0.08 13.1 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 EME89147.1 - 8.9e-37 123.6 6.2 7.3e-08 32.0 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat LRR_8 PF13855.1 EME89150.1 - 1.7e-16 59.7 22.6 8.3e-10 38.2 4.2 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EME89150.1 - 1.2e-15 56.6 11.3 2.4e-08 33.4 2.4 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EME89150.1 - 2.4e-09 35.9 13.1 0.016 15.1 0.0 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EME89150.1 - 8.3e-07 28.4 10.5 3.3 8.0 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 EME89150.1 - 2.2e-05 23.9 13.7 4 8.0 0.0 6.2 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.1 EME89150.1 - 0.012 15.1 0.8 0.042 13.4 0.6 1.8 1 1 0 1 1 1 0 Leucine-rich repeat Metallophos PF00149.23 EME89152.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1687 PF07955.6 EME89153.1 - 5.6e-17 61.9 0.6 2e-16 60.1 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EME89153.1 - 0.004 17.2 0.0 0.022 14.8 0.0 2.3 1 1 1 2 2 2 1 ArsC family RRM_1 PF00076.17 EME89154.1 - 0.02 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQ-loop PF04193.9 EME89155.1 - 3e-17 61.8 10.8 3e-14 52.2 1.3 3.4 3 1 1 4 4 4 2 PQ loop repeat PfkB PF00294.19 EME89156.1 - 1e-22 80.6 0.0 1.5e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4285 PF14113.1 EME89156.1 - 0.032 14.2 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4285) HET PF06985.6 EME89157.1 - 3e-31 108.4 4.6 5e-31 107.7 3.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_1 PF00300.17 EME89158.1 - 1.4e-18 67.4 0.0 1.9e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M75 PF09375.5 EME89158.1 - 0.026 13.8 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Imelysin Dna2 PF08696.6 EME89159.1 - 1e-61 207.9 0.2 1.8e-61 207.0 0.2 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EME89159.1 - 2e-49 167.6 0.0 3.7e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EME89159.1 - 5.9e-40 137.3 0.2 8.2e-37 127.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EME89159.1 - 1.3e-13 50.9 0.0 5.2e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EME89159.1 - 2.1e-12 46.5 0.7 1.8e-11 43.5 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain PDDEXK_1 PF12705.2 EME89159.1 - 2.1e-09 37.1 0.0 5.5e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EME89159.1 - 1.1e-07 31.9 0.2 0.00015 21.7 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF83 UvrD-helicase PF00580.16 EME89159.1 - 3.6e-06 26.5 0.1 8.4e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EME89159.1 - 5e-06 26.2 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EME89159.1 - 2.4e-05 23.9 0.2 0.33 10.4 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EME89159.1 - 0.00036 19.6 0.1 0.0011 17.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EME89159.1 - 0.0029 17.7 1.8 0.13 12.3 0.0 3.6 4 1 0 4 4 3 1 AAA domain SRP54 PF00448.17 EME89159.1 - 0.0034 16.8 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EME89159.1 - 0.004 16.5 0.0 0.0093 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME89159.1 - 0.0043 17.0 0.2 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF911 PF06023.7 EME89159.1 - 0.0059 15.8 0.1 0.037 13.2 0.0 2.2 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) ResIII PF04851.10 EME89159.1 - 0.011 15.5 0.1 0.038 13.8 0.1 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.12 EME89159.1 - 0.022 14.5 0.1 0.068 12.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 CbiA PF01656.18 EME89159.1 - 0.027 13.8 0.1 0.076 12.4 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 EME89159.1 - 0.036 13.5 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EME89159.1 - 0.044 13.2 0.0 0.15 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA-like domain PEPCK_ATP PF01293.15 EME89159.1 - 0.051 12.0 0.0 0.091 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA PF00004.24 EME89159.1 - 0.053 13.7 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EME89159.1 - 0.063 12.9 0.2 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EME89159.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EME89159.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0122 PF04297.9 EME89159.1 - 0.16 12.0 0.1 28 4.8 0.0 2.6 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like WH2 PF02205.15 EME89160.1 - 3.5e-08 32.7 0.3 8.9e-08 31.4 0.2 1.7 1 0 0 1 1 1 1 WH2 motif DUF913 PF06025.7 EME89163.1 - 5.9e-99 331.3 0.0 5.9e-99 331.3 0.0 5.1 5 0 0 5 5 5 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EME89163.1 - 1.8e-96 323.0 0.4 3.3e-96 322.1 0.2 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EME89163.1 - 1.7e-64 218.2 0.8 1.7e-64 218.2 0.5 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EME89163.1 - 2.6e-23 82.0 15.5 2.6e-23 82.0 10.8 5.3 4 2 2 6 6 6 1 Domain of unknown function (DUF4414) Pax2_C PF12403.3 EME89164.1 - 0.071 12.7 0.1 0.072 12.7 0.0 1.0 1 0 0 1 1 1 0 Paired-box protein 2 C terminal WD40 PF00400.27 EME89165.1 - 5.8e-50 165.4 23.1 7e-12 44.7 0.5 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EME89165.1 - 3.5e-09 36.6 10.6 0.016 14.9 0.2 4.6 1 1 4 6 6 6 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EME89165.1 - 0.00021 19.2 4.0 0.0014 16.5 0.1 2.1 2 0 0 2 2 2 2 IKI3 family YmzC PF14157.1 EME89165.1 - 0.0052 16.5 0.0 1.3 8.8 0.0 3.8 5 0 0 5 5 5 1 YmzC-like protein Kelch_6 PF13964.1 EME89165.1 - 0.026 14.7 0.5 0.4 10.9 0.0 2.7 2 0 0 2 2 2 0 Kelch motif UPF0020 PF01170.13 EME89167.1 - 1.4e-10 41.0 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EME89167.1 - 4.2e-07 30.0 0.1 1.5e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 EME89167.1 - 0.07 12.5 0.2 0.34 10.3 0.0 2.0 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase NUC173 PF08161.7 EME89168.1 - 5.8e-54 182.4 0.0 1.1e-50 171.7 0.0 3.0 2 0 0 2 2 2 2 NUC173 domain Vac14_Fab1_bd PF12755.2 EME89168.1 - 0.11 12.8 0.0 35 4.8 0.0 4.0 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region CRC_subunit PF08624.5 EME89170.1 - 1.3e-54 183.8 0.0 1.9e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Peptidase_S8 PF00082.17 EME89172.1 - 6.7e-15 54.9 0.3 7.3e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EME89174.1 - 2.4e-66 220.0 3.7 6.1e-20 71.3 0.0 4.9 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EME89174.1 - 1e-57 189.2 20.8 4.1e-08 32.6 0.0 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 EME89174.1 - 3.9e-50 167.3 11.6 2.1e-13 50.3 0.0 7.8 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME89174.1 - 5.7e-40 131.3 7.6 4e-05 23.4 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 EME89174.1 - 8.3e-38 127.5 14.2 1e-09 38.2 0.3 8.4 1 1 9 10 10 10 10 Ankyrin repeats (many copies) DUF1815 PF08844.5 EME89174.1 - 0.13 11.9 0.1 2.3 7.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1815) DUF1843 PF08898.5 EME89174.1 - 0.13 12.2 2.0 4.1 7.5 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) Ank PF00023.25 EME89175.1 - 4.7e-24 82.9 0.1 1.2e-07 31.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EME89175.1 - 1.7e-22 79.5 0.5 5.2e-11 42.7 0.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EME89175.1 - 1.1e-18 66.8 0.2 9.1e-08 32.1 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EME89175.1 - 6.5e-15 53.7 0.5 0.00096 19.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EME89175.1 - 2.4e-14 53.3 0.0 3.7e-10 40.0 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.7 EME89175.1 - 2.1e-10 40.4 0.0 6.1e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EME89175.1 - 0.0039 16.2 0.0 0.0082 15.1 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 EME89175.1 - 0.021 14.9 0.0 0.13 12.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.1 EME89175.1 - 0.023 14.4 0.0 0.1 12.4 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EME89175.1 - 0.081 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain HlyIII PF03006.15 EME89176.1 - 2.2e-46 158.0 20.3 2.6e-46 157.7 14.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related CBFD_NFYB_HMF PF00808.18 EME89177.1 - 2.5e-08 33.8 0.0 6.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EME89177.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SPX PF03105.14 EME89177.1 - 0.16 11.7 7.2 0.18 11.5 5.0 1.2 1 0 0 1 1 1 0 SPX domain Daxx PF03344.10 EME89177.1 - 0.24 9.8 24.1 0.48 8.8 16.7 1.5 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EME89177.1 - 0.33 9.9 23.7 0.47 9.4 16.4 1.2 1 0 0 1 1 1 0 BUD22 F-box-like_2 PF13013.1 EME89178.1 - 0.084 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 F-box-like domain FB_lectin PF07367.6 EME89178.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal fruit body lectin LSM PF01423.17 EME89180.1 - 2.3e-14 52.7 0.3 2.9e-14 52.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hist_rich_Ca-bd PF10529.4 EME89180.1 - 1.1 9.3 10.2 2.4 8.2 7.1 1.6 1 0 0 1 1 1 0 Histidine-rich Calcium-binding repeat region SNF2_N PF00176.18 EME89181.1 - 9.1e-66 221.6 0.2 1.4e-65 221.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EME89181.1 - 8.5e-21 73.3 1.7 1.3e-11 44.0 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EME89181.1 - 2.5e-13 49.6 0.0 5.6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FF PF01846.14 EME89183.1 - 5e-36 122.4 18.6 2.3e-12 46.6 1.5 5.1 4 0 0 4 4 4 4 FF domain WW PF00397.21 EME89183.1 - 5.1e-18 64.5 10.6 4.1e-09 36.1 0.7 2.6 2 0 0 2 2 2 2 WW domain Vps51 PF08700.6 EME89183.1 - 1.3 8.8 6.7 2.4 8.0 0.5 2.8 2 0 0 2 2 2 0 Vps51/Vps67 p450 PF00067.17 EME89186.1 - 1.2e-71 241.6 0.0 1.8e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EME89186.1 - 7.2e-30 104.0 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EME89186.1 - 2.7e-16 59.8 0.0 7.7e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EME89186.1 - 5.1e-14 52.7 0.0 2.6e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EME89186.1 - 0.096 12.5 0.0 0.57 10.0 0.0 2.3 2 1 1 3 3 3 0 Ferric reductase NAD binding domain MFS_1 PF07690.11 EME89187.1 - 6e-27 94.2 41.3 2.4e-19 69.2 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME89187.1 - 1.4e-20 73.2 18.0 3e-20 72.2 12.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Fork_head PF00250.13 EME89188.1 - 2e-36 123.8 0.2 4.1e-36 122.8 0.1 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EME89188.1 - 5.7e-09 35.9 0.3 2.3e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 FHA domain Methyltransf_24 PF13578.1 EME89188.1 - 5e-05 24.0 0.0 0.00012 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME89188.1 - 0.067 13.7 0.0 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF791 PF05631.9 EME89189.1 - 4.1e-70 236.2 11.2 5.2e-70 235.9 7.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EME89189.1 - 2.4e-22 79.1 32.2 2.9e-22 78.8 22.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EME89189.1 - 1.2e-07 30.6 21.4 3.5e-07 29.1 6.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter HLH PF00010.21 EME89191.1 - 2.3e-11 43.1 0.5 2e-10 40.2 0.0 2.5 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DFF40 PF09230.5 EME89191.1 - 0.032 13.6 0.1 0.073 12.4 0.0 1.6 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa PEP-utilisers_N PF05524.8 EME89191.1 - 0.047 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Vps23_core PF09454.5 EME89191.1 - 0.095 12.3 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Vps23 core domain bZIP_2 PF07716.10 EME89191.1 - 0.11 12.3 1.5 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF1686 PF07937.6 EME89192.1 - 0.085 12.4 0.1 0.094 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) SNF2_N PF00176.18 EME89193.1 - 1.7e-71 240.4 0.0 4.2e-71 239.2 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EME89193.1 - 2.8e-11 43.1 0.0 8e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PKI PF02827.11 EME89193.1 - 0.85 9.7 9.8 0.087 12.9 2.4 2.5 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor eIF-1a PF01176.14 EME89196.1 - 3e-28 97.0 0.0 4.2e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EME89197.1 - 2.4e-29 101.3 0.4 3.4e-29 100.7 0.3 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EME89197.1 - 3.9e-06 26.2 0.4 9.2e-06 25.1 0.3 1.6 1 0 0 1 1 1 1 WH2 motif SET PF00856.23 EME89198.1 - 8e-18 65.2 0.3 3.4e-17 63.2 0.2 1.9 1 1 0 1 1 1 1 SET domain G-alpha PF00503.15 EME89199.1 - 6e-132 440.0 1.3 7.2e-132 439.7 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EME89199.1 - 2.1e-15 56.3 2.0 9.6e-11 41.2 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EME89199.1 - 0.00019 20.8 0.0 0.00086 18.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EME89199.1 - 0.0017 18.8 0.5 3.1 8.3 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EME89199.1 - 0.0056 15.8 3.8 0.19 10.8 0.1 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EME89199.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.18 EME89199.1 - 0.015 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family GTP_EFTU PF00009.22 EME89199.1 - 0.03 13.7 0.1 2.1 7.7 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Mog1 PF04603.7 EME89199.1 - 0.076 12.9 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Ran-interacting Mog1 protein MMR_HSR1 PF01926.18 EME89199.1 - 0.097 12.6 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EME89199.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family LIM PF00412.17 EME89201.1 - 1.8e-22 79.1 18.2 2.5e-13 49.8 2.8 2.9 3 0 0 3 3 3 2 LIM domain MIS13 PF08202.6 EME89203.1 - 8.3e-44 149.8 0.0 8.3e-44 149.8 0.0 1.8 2 1 0 2 2 2 1 Mis12-Mtw1 protein family tRNA_anti-codon PF01336.20 EME89204.1 - 0.0038 17.0 0.0 0.018 14.8 0.0 2.1 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain MBA1 PF07961.6 EME89204.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein RNase_PH PF01138.16 EME89205.1 - 4.8e-11 43.1 0.0 7.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF2365 PF10157.4 EME89206.1 - 0.049 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) TPP_enzyme_N PF02776.13 EME89207.1 - 9.7e-47 158.6 0.4 7.8e-46 155.6 1.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EME89207.1 - 7.5e-39 132.7 0.2 6.7e-37 126.4 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EME89207.1 - 5.9e-22 77.9 0.0 1.2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EME89207.1 - 0.016 14.7 0.0 0.048 13.2 0.0 1.7 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit UPF0029 PF01205.14 EME89208.1 - 2.1e-16 59.5 0.2 5.1e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Spindle_Spc25 PF08234.7 EME89209.1 - 4.9e-20 71.2 0.1 3.8e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Cortex-I_coil PF09304.5 EME89209.1 - 0.0008 19.4 14.7 0.0038 17.2 9.1 2.3 1 1 1 2 2 2 1 Cortexillin I, coiled coil AAA_13 PF13166.1 EME89209.1 - 0.048 12.1 8.3 0.062 11.7 5.7 1.1 1 0 0 1 1 1 0 AAA domain DUF148 PF02520.12 EME89209.1 - 0.055 13.2 11.1 0.019 14.7 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF148 Rgp1 PF08737.5 EME89209.1 - 0.12 11.4 3.3 0.15 11.1 2.3 1.1 1 0 0 1 1 1 0 Rgp1 DUF342 PF03961.8 EME89209.1 - 0.13 10.7 4.7 0.17 10.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AlaDh_PNT_C PF01262.16 EME89209.1 - 1.4 8.4 4.3 0.69 9.4 0.1 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TMPIT PF07851.8 EME89209.1 - 2.7 6.9 9.4 3.9 6.4 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein FimP PF09766.4 EME89209.1 - 4.4 6.2 13.7 4.3 6.3 0.4 1.6 1 1 1 2 2 2 0 Fms-interacting protein Mnd1 PF03962.10 EME89209.1 - 5.9 6.4 18.4 0.36 10.4 4.2 2.2 1 1 1 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 EME89209.1 - 8.6 6.2 12.1 2.3 8.0 3.8 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Rrn6 PF10214.4 EME89210.1 - 3.8e-76 256.7 0.0 5.2e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF3381 PF11861.3 EME89210.1 - 0.45 10.0 6.0 0.74 9.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) ESSS PF10183.4 EME89213.1 - 9.6e-30 103.0 0.0 1.1e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 EME89213.1 - 0.15 11.6 2.4 0.26 10.8 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) AAL_decarboxy PF03306.8 EME89214.1 - 5.7e-65 218.4 0.0 6.4e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Polysacc_lyase PF14099.1 EME89214.1 - 0.0091 15.6 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide lyase RNB PF00773.14 EME89215.1 - 2e-85 286.9 0.1 7.6e-85 285.0 0.0 2.0 2 0 0 2 2 2 1 RNB domain GLE1 PF07817.8 EME89216.1 - 8.3e-11 41.3 0.0 8.3e-11 41.3 0.0 2.7 2 1 1 3 3 3 2 GLE1-like protein AAA PF00004.24 EME89217.1 - 3.8e-15 56.2 0.0 9.5e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME89217.1 - 1e-10 41.9 0.0 4.4e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME89217.1 - 3.3e-08 33.7 0.0 1.8e-07 31.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain BAH PF01426.13 EME89217.1 - 9e-07 28.6 0.0 3.5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 BAH domain AAA_19 PF13245.1 EME89217.1 - 0.0002 21.0 0.3 0.00078 19.1 0.2 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EME89217.1 - 0.0081 16.9 0.0 0.055 14.2 0.0 2.5 3 0 0 3 3 1 1 AAA domain AAA_18 PF13238.1 EME89217.1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME89217.1 - 0.019 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME89217.1 - 0.031 13.9 0.0 0.098 12.3 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EME89217.1 - 0.035 13.0 0.0 0.079 11.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EME89217.1 - 0.044 13.3 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EME89217.1 - 0.091 12.4 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.9 EME89217.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_32 PF13654.1 EME89217.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EME89217.1 - 0.16 12.1 0.0 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF1604 PF07713.8 EME89217.1 - 0.2 11.4 1.1 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Pirin PF02678.11 EME89219.1 - 9.1e-32 109.1 0.2 2e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EME89219.1 - 1.8e-21 76.1 0.0 1e-20 73.7 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EME89219.1 - 1.4e-05 24.5 0.8 0.00067 19.1 0.4 2.3 2 0 0 2 2 2 1 Cupin domain zf-TRM13_CCCH PF11722.3 EME89220.1 - 0.047 13.0 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein WD40 PF00400.27 EME89221.1 - 2.6e-52 172.9 15.3 6e-09 35.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EME89221.1 - 0.00065 17.9 1.2 0.41 8.7 0.1 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EME89221.1 - 0.0088 15.5 0.3 3 7.2 0.1 2.9 1 1 2 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 EME89221.1 - 0.11 12.2 0.0 14 5.5 0.0 3.3 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Tannase PF07519.6 EME89222.1 - 1.3e-100 337.3 0.3 2.2e-100 336.6 0.2 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase WD40 PF00400.27 EME89223.1 - 2.8e-51 169.6 19.5 1.1e-10 40.9 0.4 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EME89223.1 - 2.8e-12 45.6 7.0 4.8e-12 44.9 4.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EME89223.1 - 0.0096 15.6 0.0 1.4 8.6 0.0 3.2 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A zf-CCCH PF00642.19 EME89224.1 - 2.2e-05 23.9 16.2 0.032 13.9 0.2 4.6 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ShK PF01549.19 EME89224.1 - 1.4 9.3 12.1 0.71 10.2 0.6 3.8 2 1 0 3 3 3 0 ShK domain-like Sel1 PF08238.7 EME89225.1 - 2e-18 66.3 8.9 2.6e-06 27.8 0.1 3.5 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EME89225.1 - 0.51 10.9 4.3 12 6.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat bZIP_2 PF07716.10 EME89226.1 - 2.2e-05 24.1 9.6 2.2e-05 24.1 6.6 2.7 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EME89226.1 - 0.0002 21.2 13.5 0.0002 21.2 9.3 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EME89226.1 - 0.0074 16.5 13.0 0.0074 16.5 9.0 2.2 1 1 1 2 2 2 1 bZIP Maf transcription factor Herpes_UL6 PF01763.11 EME89226.1 - 0.18 9.9 7.6 0.25 9.4 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like RE_AlwI PF09491.5 EME89226.1 - 0.72 8.2 10.6 5.3 5.4 5.7 2.1 2 0 0 2 2 2 0 AlwI restriction endonuclease IncA PF04156.9 EME89226.1 - 0.74 9.3 20.5 1.1 8.8 13.2 1.9 1 1 0 1 1 1 0 IncA protein DUF724 PF05266.9 EME89226.1 - 5.9 6.4 12.9 10 5.6 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Arabino_trans_C PF14896.1 EME89227.1 - 0.027 13.0 0.1 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain Ribosomal_S8e PF01201.17 EME89228.1 - 4e-33 114.3 8.2 1.5e-32 112.4 5.7 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e P4Ha_N PF08336.6 EME89228.1 - 0.17 11.7 3.3 0.26 11.1 1.8 1.5 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2390 PF09523.5 EME89228.1 - 2.4 8.3 5.9 4.8 7.4 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF566 PF04484.7 EME89229.1 - 8.8 5.7 8.8 2 7.8 3.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF566) BNR PF02012.15 EME89230.1 - 1.7e-11 42.1 37.9 0.26 11.2 0.1 11.1 11 0 0 11 11 11 8 BNR/Asp-box repeat DUF2561 PF10812.3 EME89230.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Ammonium_transp PF00909.16 EME89231.1 - 4.1e-115 384.4 31.4 4.7e-115 384.2 21.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Corona_NS2 PF04753.7 EME89231.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 PHD PF00628.24 EME89233.1 - 2.6e-09 36.6 8.8 6e-09 35.4 6.1 1.6 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 EME89233.1 - 1.6e-08 33.9 0.0 3.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EME89233.1 - 0.00062 19.5 1.5 0.02 14.6 0.9 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family PHD_2 PF13831.1 EME89233.1 - 0.0014 17.9 2.9 0.003 16.8 2.0 1.6 1 0 0 1 1 1 1 PHD-finger Kdo PF06293.9 EME89233.1 - 0.0026 16.8 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EME89233.1 - 0.0088 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 EME89233.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2602 PF10782.4 EME89233.1 - 0.026 14.3 0.2 0.071 12.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) zf-HC5HC2H PF13771.1 EME89233.1 - 0.053 13.6 2.6 0.14 12.3 1.8 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF2201_N PF13203.1 EME89233.1 - 2.7 7.0 9.9 5.4 6.0 6.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Amino_oxidase PF01593.19 EME89234.1 - 1.2e-52 179.4 0.3 3.4e-52 178.0 0.2 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EME89234.1 - 1.7e-11 43.9 0.1 4.6e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME89234.1 - 2.4e-07 30.0 0.2 2.1e-06 26.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EME89234.1 - 2.6e-06 26.5 1.4 2.6e-06 26.5 1.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EME89234.1 - 3.8e-06 27.1 0.2 8.9e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EME89234.1 - 1.3e-05 25.3 0.2 8.8e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME89234.1 - 1.5e-05 23.6 0.5 0.00026 19.6 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EME89234.1 - 1.7e-05 24.0 0.5 2.8e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EME89234.1 - 2.8e-05 23.4 0.3 4.4e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EME89234.1 - 4.7e-05 22.5 0.2 0.00011 21.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EME89234.1 - 0.00017 21.4 0.1 0.00035 20.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME89234.1 - 0.0024 17.6 0.1 0.17 11.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EME89234.1 - 0.0034 16.3 0.2 0.0061 15.4 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EME89234.1 - 0.015 14.2 0.5 0.031 13.2 0.4 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EME89234.1 - 0.016 15.4 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EME89234.1 - 0.19 11.7 0.6 1.6 8.7 0.1 2.5 3 0 0 3 3 3 0 TrkA-N domain HAT PF02184.11 EME89236.1 - 3.5e-22 77.8 50.1 1.2e-14 53.7 2.5 10.2 11 0 0 11 11 11 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EME89236.1 - 4.4e-20 70.3 9.9 0.0037 17.7 0.1 9.8 6 2 5 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EME89236.1 - 1.4e-14 54.2 8.2 0.0038 17.8 0.0 8.0 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME89236.1 - 4.4e-12 46.1 0.0 0.00072 19.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EME89236.1 - 5.6e-09 35.7 3.4 0.092 12.6 0.0 6.1 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EME89236.1 - 6.4e-09 35.3 0.2 0.0045 17.0 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EME89236.1 - 1.1e-08 34.2 12.6 0.0069 16.2 0.1 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EME89236.1 - 5.7e-08 32.1 10.2 0.21 10.5 0.3 5.5 1 1 2 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 EME89236.1 - 5.9e-08 32.7 16.2 0.0043 16.8 0.1 5.3 2 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EME89236.1 - 8.2e-08 31.7 5.7 0.14 11.8 0.0 5.8 4 3 2 6 6 6 3 TPR repeat U3_assoc_6 PF08640.6 EME89236.1 - 2.8e-06 27.0 20.3 0.1 12.3 0.9 6.5 3 2 3 6 6 6 3 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 EME89236.1 - 0.00015 21.6 13.7 7.2 6.6 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 EME89236.1 - 0.11 12.3 3.9 38 4.3 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4105 PF13387.1 EME89236.1 - 0.12 11.5 1.6 1.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) TPR_1 PF00515.23 EME89236.1 - 0.13 11.9 5.5 8.4 6.1 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME89236.1 - 1.8 9.2 16.7 26 5.5 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Prp31_C PF09785.4 EME89237.1 - 8.3e-46 155.4 1.4 1.1e-45 155.0 0.2 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EME89237.1 - 8.4e-41 138.7 0.7 1.5e-40 137.9 0.5 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EME89237.1 - 4e-21 74.5 0.0 3.4e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain Nop14 PF04147.7 EME89237.1 - 8.2 4.2 11.8 12 3.6 8.2 1.2 1 0 0 1 1 1 0 Nop14-like family Pyrid_oxidase_2 PF13883.1 EME89238.1 - 1.4e-35 122.5 0.0 1.9e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase VGCC_beta4Aa_N PF12052.3 EME89238.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ribosomal_S30 PF04758.9 EME89239.1 - 1.8e-29 101.2 7.4 1.9e-29 101.1 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Med8 PF10232.4 EME89241.1 - 1.8e-27 96.3 0.1 2.1e-27 96.1 0.0 1.2 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Glyco_hydro_76 PF03663.9 EME89242.1 - 5.2e-159 529.5 21.2 6.4e-159 529.2 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DNA_methylase PF00145.12 EME89243.1 - 2.9e-33 115.3 0.0 1.4e-21 77.0 0.0 2.4 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_2 PF00310.16 EME89244.1 - 3.6e-20 71.9 0.0 1.3e-14 53.7 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EME89244.1 - 9.8e-16 57.9 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EME89244.1 - 4.3e-14 52.3 0.0 7.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EME89244.1 - 7.9e-11 41.7 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EME89244.1 - 0.0001 21.0 0.0 0.00017 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Cellulase PF00150.13 EME89245.1 - 6.5e-52 176.4 4.2 8.3e-52 176.1 2.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_4 PF14295.1 EME89246.1 - 5e-07 29.3 1.2 5e-07 29.3 0.9 3.1 3 0 0 3 3 3 1 PAN domain PAN_2 PF08276.6 EME89246.1 - 0.005 16.6 1.4 0.005 16.6 0.9 2.6 2 1 0 2 2 2 1 PAN-like domain CPSF100_C PF13299.1 EME89246.1 - 0.42 10.7 3.4 0.78 9.9 2.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal IMS PF00817.15 EME89247.1 - 3.4e-42 143.7 0.1 7.4e-42 142.6 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EME89247.1 - 2.2e-17 63.1 0.0 5.5e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EME89247.1 - 0.00016 21.4 0.0 0.0005 19.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Abhydrolase_6 PF12697.2 EME89249.1 - 5e-25 88.7 0.0 8.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME89249.1 - 8.1e-13 48.4 0.0 9.4e-11 41.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME89249.1 - 4e-12 46.0 0.0 1.8e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EME89249.1 - 0.0004 20.1 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 EME89249.1 - 0.036 13.7 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EME89249.1 - 0.044 13.2 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Cyclin_N PF00134.18 EME89250.1 - 2.1e-34 117.8 0.6 3.8e-34 116.9 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EME89250.1 - 2.2e-15 56.6 0.4 5e-15 55.4 0.3 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain WD40 PF00400.27 EME89251.1 - 1.3e-08 34.3 24.0 0.53 10.2 0.3 9.5 10 0 0 10 10 10 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EME89251.1 - 0.00014 21.3 0.4 0.064 12.6 0.0 4.2 3 1 0 3 3 3 1 PQQ-like domain SUR7 PF06687.7 EME89252.1 - 8.1e-34 117.0 14.7 9.7e-34 116.7 10.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Rad4 PF03835.10 EME89254.1 - 2.7e-15 56.0 0.5 5e-15 55.1 0.4 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EME89254.1 - 4.1e-10 39.8 1.5 8.6e-10 38.8 1.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily LtrA PF06772.6 EME89255.1 - 2.7e-20 72.6 19.4 2.7e-20 72.6 13.4 1.4 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) zf-met PF12874.2 EME89256.1 - 0.0049 17.0 1.4 0.0085 16.2 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME89256.1 - 0.0083 16.2 1.0 0.017 15.2 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME89256.1 - 0.097 12.7 0.4 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CDC27 PF09507.5 EME89256.1 - 0.16 11.1 28.4 0.23 10.6 19.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Fzo_mitofusin PF04799.8 EME89256.1 - 3.8 6.8 6.3 1.6 8.1 0.6 2.3 1 1 1 2 2 2 0 fzo-like conserved region CorA PF01544.13 EME89256.1 - 5.2 6.0 6.1 8.1 5.3 4.2 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TFIIS_M PF07500.9 EME89257.1 - 5.3e-16 58.7 0.4 1.3e-15 57.4 0.3 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EME89257.1 - 2.9e-13 50.3 0.0 6.7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EME89257.1 - 1.3e-09 37.5 7.7 2.3e-09 36.8 5.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EME89257.1 - 0.094 12.0 3.1 0.16 11.3 2.1 1.3 1 0 0 1 1 1 0 PHD-finger tRNA-synt_2 PF00152.15 EME89258.1 - 2e-86 289.8 0.3 3.2e-86 289.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EME89258.1 - 1.4e-07 31.2 0.1 1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EME89258.1 - 2.1e-06 27.1 0.2 0.006 15.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EME89258.1 - 0.032 13.8 0.1 0.22 11.1 0.0 2.2 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF1431 PF07248.7 EME89258.1 - 0.13 12.2 0.1 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) EnY2 PF10163.4 EME89259.1 - 1.7e-05 24.6 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF2004 PF09406.5 EME89259.1 - 0.0028 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2004) MFS_1 PF07690.11 EME89260.1 - 9.3e-34 116.6 19.8 7.2e-33 113.7 12.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EME89262.1 - 3.6e-74 249.1 0.0 4.1e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89262.1 - 1.8e-36 125.5 0.0 2.3e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME89262.1 - 0.00052 19.0 0.0 0.0018 17.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EME89262.1 - 0.026 14.2 0.0 0.093 12.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EME89262.1 - 0.029 13.4 0.0 0.076 12.0 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Patatin PF01734.17 EME89264.1 - 1.7e-23 83.5 0.0 3.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.3 EME89264.1 - 3.2e-21 75.3 0.8 4.7e-21 74.8 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Na_H_Exchanger PF00999.16 EME89265.1 - 5.9e-72 242.3 46.3 8.2e-72 241.8 32.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Reo_sigmaC PF04582.7 EME89266.1 - 0.023 13.9 40.2 0.11 11.6 3.2 5.1 2 1 3 5 5 5 0 Reovirus sigma C capsid protein ARID PF01388.16 EME89271.1 - 1.3e-16 60.1 0.1 3e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain GLTP PF08718.6 EME89271.1 - 0.14 12.1 0.0 0.78 9.7 0.0 2.0 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) zf-C2H2_4 PF13894.1 EME89271.1 - 1 9.8 2.8 2.3 8.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SIS PF01380.17 EME89273.1 - 2.1e-08 33.8 0.2 1.2e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EME89273.1 - 0.00015 21.5 0.2 0.02 14.6 0.1 2.3 1 1 1 2 2 2 2 SIS domain Transglut_core PF01841.14 EME89273.1 - 0.03 14.5 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ubie_methyltran PF01209.13 EME89274.1 - 1.4e-74 250.1 0.0 2.6e-74 249.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EME89274.1 - 2e-14 53.4 0.0 3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EME89274.1 - 4e-13 49.6 0.0 7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME89274.1 - 1.4e-10 41.4 0.1 3.9e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EME89274.1 - 1.6e-10 40.9 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EME89274.1 - 4.1e-10 39.9 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME89274.1 - 2.5e-07 31.2 0.0 5.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EME89274.1 - 4.6e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EME89274.1 - 0.0094 15.3 0.0 0.017 14.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EME89274.1 - 0.034 14.9 0.0 0.073 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain E1_dh PF00676.15 EME89275.1 - 2.6e-88 295.5 0.0 3.4e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EME89275.1 - 4.5e-05 23.0 0.9 0.00046 19.7 0.1 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EME89275.1 - 0.014 14.3 0.0 0.055 12.3 0.0 1.8 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DEAD PF00270.24 EME89276.1 - 4.9e-40 136.7 0.0 1.1e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EME89276.1 - 6.3e-23 80.4 0.1 1.9e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EME89276.1 - 2.9e-06 25.9 0.0 1.6e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) SNF2_N PF00176.18 EME89276.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EME89276.1 - 0.014 15.5 0.1 0.049 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EME89276.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HECT PF00632.20 EME89277.1 - 9e-54 182.7 0.0 1.2e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PCAF_N PF06466.6 EME89277.1 - 0.071 12.4 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain adh_short_C2 PF13561.1 EME89278.1 - 4.4e-25 88.8 0.6 5.2e-25 88.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EME89278.1 - 4.6e-25 88.4 3.7 6.2e-25 88.0 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME89278.1 - 4.6e-17 62.2 2.0 6e-17 61.8 1.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME89278.1 - 9.6e-08 31.7 0.1 2e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME89278.1 - 0.012 14.3 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EME89278.1 - 0.013 14.4 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.16 EME89278.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Stirrup PF09061.1 EME89278.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Stirrup Complex1_30kDa PF00329.14 EME89279.1 - 6e-36 122.7 0.1 8.8e-36 122.2 0.1 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 EME89280.1 - 2.5e-20 71.8 12.4 4.5e-20 70.9 8.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EME89280.1 - 1e-09 37.8 0.0 3.3e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EME89280.1 - 7.9e-06 25.4 7.7 1.8e-05 24.3 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EME89280.1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EME89280.1 - 1.9e-05 24.0 2.5 1.9e-05 24.0 1.7 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EME89280.1 - 0.00051 19.8 9.8 0.0011 18.7 6.8 1.6 1 0 0 1 1 1 1 Ring finger domain FYVE_2 PF02318.11 EME89280.1 - 0.0014 18.5 2.6 0.0014 18.5 1.8 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger Baculo_IE-1 PF05290.6 EME89280.1 - 0.0015 18.3 3.7 0.0015 18.3 2.5 1.7 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 EME89280.1 - 0.0025 17.7 0.0 0.0058 16.5 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EME89280.1 - 0.0038 16.9 6.0 0.011 15.4 3.1 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger FYVE PF01363.16 EME89280.1 - 0.014 15.2 4.6 0.036 13.9 3.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.20 EME89280.1 - 0.017 14.7 10.2 0.045 13.4 7.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME89280.1 - 0.11 12.2 10.5 0.26 11.0 7.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PLAC8 PF04749.12 EME89281.1 - 2.5e-05 24.7 0.0 3.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PLAC8 family DUF619 PF04768.8 EME89282.1 - 4.3e-47 159.6 0.0 1.3e-46 158.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EME89282.1 - 2.9e-32 111.4 0.0 1.5e-31 109.2 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EME89282.1 - 1e-27 97.2 0.2 2.9e-27 95.7 0.1 1.8 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EME89282.1 - 0.0011 18.8 0.0 0.0031 17.4 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EME89282.1 - 0.011 16.2 0.0 0.037 14.5 0.0 2.0 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EME89282.1 - 0.031 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase CorA PF01544.13 EME89283.1 - 2.8e-08 33.1 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GDI PF00996.13 EME89284.1 - 3.1e-41 141.1 0.0 3.9e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Redoxin PF08534.5 EME89285.1 - 7.1e-36 122.9 0.1 8.1e-36 122.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EME89285.1 - 3.3e-12 46.1 0.0 3.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Aldedh PF00171.17 EME89286.1 - 5.7e-113 377.6 0.0 7.2e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 EME89288.1 - 1.2e-10 41.5 0.1 3.9e-10 39.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME89288.1 - 5e-06 26.2 0.8 7.3e-06 25.7 0.1 1.5 2 0 0 2 2 2 1 KR domain DinB_2 PF12867.2 EME89288.1 - 0.038 14.3 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 DinB superfamily adh_short_C2 PF13561.1 EME89288.1 - 0.047 13.4 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NACHT PF05729.7 EME89289.1 - 3.5e-05 23.5 0.0 0.00011 21.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME89289.1 - 5e-05 23.3 0.4 0.00026 21.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME89289.1 - 6.6e-05 23.0 0.1 0.00034 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain WD40 PF00400.27 EME89289.1 - 0.00087 19.0 0.8 0.065 13.1 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF676 PF05057.9 EME89289.1 - 0.0058 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_19 PF13245.1 EME89289.1 - 0.097 12.4 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EME89289.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 EME89289.1 - 0.23 11.2 0.1 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 HET PF06985.6 EME89290.1 - 6.6e-19 68.4 3.0 1.2e-18 67.5 2.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 EME89291.1 - 2.5e-93 312.3 0.0 3.9e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME89291.1 - 6.6e-57 192.6 0.3 3.3e-56 190.3 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME89291.1 - 1.5e-13 50.4 0.0 3.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ParA PF10609.4 EME89292.1 - 1.6e-32 111.1 0.2 4.1e-32 109.8 0.1 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EME89292.1 - 1.6e-13 50.5 0.0 2.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EME89292.1 - 2.8e-08 33.8 0.1 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EME89292.1 - 1.9e-06 27.1 0.0 2.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 EME89292.1 - 4.1e-06 26.1 0.0 0.049 12.8 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 EME89292.1 - 7.1e-06 25.2 0.6 0.00015 20.9 0.2 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EME89292.1 - 0.0051 16.2 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EME89292.1 - 0.027 14.0 0.2 3 7.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EME89292.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Epimerase PF01370.16 EME89293.1 - 1.4e-08 34.4 0.1 6.8e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME89293.1 - 6.7e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EME89293.1 - 5.8e-05 22.1 0.0 0.00034 19.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EME89293.1 - 0.00053 19.0 0.0 0.00079 18.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EME89293.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EME89293.1 - 0.033 13.4 0.0 0.069 12.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.14 EME89293.1 - 0.075 11.7 0.1 0.4 9.3 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rick_17kDa_Anti PF05433.10 EME89294.1 - 0.00015 21.3 10.0 0.00023 20.7 7.0 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EME89294.1 - 0.00035 20.2 0.0 0.00067 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EME89294.1 - 0.00093 18.7 5.6 0.0016 18.0 3.9 1.3 1 0 0 1 1 1 1 Glycine zipper Bacteriocin_IIc PF10439.4 EME89294.1 - 0.087 12.9 5.5 0.14 12.3 3.8 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 EME89294.1 - 6.3 6.4 14.0 15 5.2 9.7 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper Pyr_redox_3 PF13738.1 EME89295.1 - 1.1e-27 97.4 0.0 1.8e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME89295.1 - 1.6e-12 46.4 0.0 2.9e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EME89295.1 - 1.3e-11 44.7 0.0 2.7e-09 37.2 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME89295.1 - 1.7e-07 31.1 0.0 4.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EME89295.1 - 1.9e-06 27.0 0.0 0.024 13.5 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EME89295.1 - 8.3e-06 24.9 0.0 0.00039 19.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME89295.1 - 5.6e-05 22.9 0.3 0.11 12.3 0.1 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EME89295.1 - 0.00032 19.6 0.0 0.00077 18.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EME89295.1 - 0.00056 19.0 0.1 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EME89295.1 - 0.037 12.9 0.1 0.064 12.1 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EME89295.1 - 0.04 14.0 0.2 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EME89295.1 - 0.061 12.4 0.1 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.14 EME89295.1 - 0.15 11.1 0.3 0.63 9.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATG13 PF10033.4 EME89296.1 - 6.1e-44 150.1 0.0 6.9e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 13 YlbE PF14003.1 EME89296.1 - 0.018 15.0 0.7 0.031 14.3 0.5 1.3 1 0 0 1 1 1 0 YlbE-like protein RCC1 PF00415.13 EME89297.1 - 3.5e-22 78.3 0.5 1.3e-06 28.5 0.0 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EME89297.1 - 1.1e-13 51.0 0.1 8.7e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EME89297.1 - 4.9e-10 39.6 0.9 5.8e-05 23.4 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EME89297.1 - 4.4e-09 35.7 1.9 4.4e-09 35.7 1.3 3.2 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EME89297.1 - 4.4e-07 29.5 0.3 0.05 13.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EME89297.1 - 6e-07 29.7 0.1 3.3e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EME89297.1 - 0.00074 19.6 0.2 0.67 10.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EME89297.1 - 0.013 15.2 0.4 3.6 7.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ndc80_HEC PF03801.8 EME89299.1 - 0.066 12.6 2.5 0.3 10.5 2.1 1.7 2 0 0 2 2 2 0 HEC/Ndc80p family BTV_NS2 PF04514.7 EME89299.1 - 0.083 11.7 0.9 0.13 11.1 0.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sec3_C PF09763.4 EME89300.1 - 2.7e-189 630.7 0.0 3.5e-189 630.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EME89300.1 - 1.4e-27 95.3 0.0 2.6e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH End3 PF12761.2 EME89300.1 - 0.00063 19.4 2.9 0.00063 19.4 2.0 1.8 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 Vps52 PF04129.7 EME89300.1 - 0.00095 17.8 0.1 0.00095 17.8 0.1 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 EME89300.1 - 0.031 14.3 0.2 0.089 12.9 0.0 1.8 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Arrestin_C PF02752.17 EME89302.1 - 2e-12 47.3 0.0 5.6e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EME89302.1 - 2.4e-09 37.2 0.0 1.6e-08 34.5 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EME89302.1 - 0.035 13.5 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like WD40 PF00400.27 EME89303.1 - 1.5e-21 75.4 14.2 1.1e-05 25.1 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EME89303.1 - 0.0013 18.4 0.1 0.0063 16.2 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EME89303.1 - 0.0021 17.6 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EME89303.1 - 0.0091 14.3 0.1 0.025 12.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EME89303.1 - 0.026 13.8 0.0 4.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature IKI3 PF04762.7 EME89303.1 - 0.067 10.9 0.0 0.55 7.9 0.0 1.7 1 1 1 2 2 2 0 IKI3 family DUF1273 PF06908.6 EME89303.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Miro PF08477.8 EME89304.1 - 1.3e-33 116.0 0.0 3.9e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EME89304.1 - 1.9e-29 101.2 0.0 4.3e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EME89304.1 - 9.3e-29 98.5 0.1 1.6e-28 97.7 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EME89304.1 - 4e-22 78.3 0.0 1.2e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EME89304.1 - 5.9e-08 32.6 0.0 0.0059 16.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EME89304.1 - 5.8e-07 29.4 0.1 0.12 12.2 0.0 3.2 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.1 EME89304.1 - 7.1e-06 26.1 0.2 0.4 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain EF-hand_7 PF13499.1 EME89304.1 - 9.5e-06 25.6 0.3 0.18 11.9 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EME89304.1 - 3e-05 23.0 1.0 0.29 10.5 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EME89304.1 - 4.3e-05 23.0 3.2 0.25 11.3 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EME89304.1 - 0.0027 16.9 3.2 0.93 8.9 0.3 2.8 2 0 0 2 2 2 2 EF hand MobB PF03205.9 EME89304.1 - 0.005 16.5 0.0 0.94 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 EME89304.1 - 0.0058 16.2 2.0 1 9.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.22 EME89304.1 - 0.014 14.8 0.0 7.5 5.9 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EME89304.1 - 0.018 14.2 0.0 1.1 8.4 0.0 3.1 2 2 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 EME89304.1 - 0.019 15.1 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 EME89304.1 - 0.021 14.4 0.3 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 EF hand Septin PF00735.13 EME89304.1 - 0.028 13.4 0.0 0.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 EME89304.1 - 0.03 13.9 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 EME89304.1 - 0.044 13.3 0.0 4.2 6.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EME89304.1 - 0.14 12.3 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.11 EME89304.1 - 0.15 11.1 0.1 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 AIG1 family UBA PF00627.26 EME89305.1 - 1.3e-06 28.0 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF3173 PF11372.3 EME89305.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) TnpV PF14198.1 EME89305.1 - 0.36 10.7 2.1 9.8 6.1 0.2 3.5 4 0 0 4 4 4 0 Transposon-encoded protein TnpV PP1c_bdg PF10488.4 EME89306.1 - 0.3 10.2 10.0 0.027 13.6 2.5 2.0 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region L27_2 PF09045.5 EME89307.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 L27_2 RRM_1 PF00076.17 EME89309.1 - 1.2e-45 153.0 0.0 5.7e-23 80.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EME89309.1 - 1.3e-37 127.5 0.0 1.9e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EME89309.1 - 2e-23 81.9 0.0 5.9e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EME89309.1 - 0.0018 18.0 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Alg6_Alg8 PF03155.10 EME89310.1 - 1.4e-123 413.1 19.4 1.9e-76 257.8 5.8 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family LRR_6 PF13516.1 EME89311.1 - 7.9e-13 47.0 4.1 0.0023 17.8 0.0 7.2 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 EME89311.1 - 2.8e-10 39.5 7.0 0.0024 17.4 0.0 5.8 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EME89311.1 - 3e-05 23.4 0.3 9.9 6.6 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 EME89311.1 - 0.0022 17.6 9.5 7.5 6.3 0.1 4.4 3 2 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EME89311.1 - 0.62 10.4 6.1 62 4.4 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat Nop14 PF04147.7 EME89311.1 - 3.3 5.4 20.7 4.1 5.2 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family Prenyltransf PF01255.14 EME89312.1 - 1.6e-07 30.7 0.0 3.4e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Transket_pyr PF02779.19 EME89313.1 - 4.5e-45 153.3 0.1 6.7e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EME89313.1 - 7.1e-32 109.9 0.1 3.6e-31 107.6 0.0 2.1 3 0 0 3 3 3 1 Transketolase, C-terminal domain Con-6 PF10346.4 EME89313.1 - 0.025 13.9 0.4 0.046 13.1 0.3 1.4 1 0 0 1 1 1 0 Conidiation protein 6 DUF2433 PF10360.4 EME89314.1 - 9.7e-47 158.5 0.0 1.6e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EME89314.1 - 0.042 13.2 0.0 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase SOG2 PF10428.4 EME89314.1 - 7.5 5.0 6.5 15 4.0 4.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Patched PF02460.13 EME89315.1 - 1.5e-79 267.8 8.3 3.2e-77 260.2 6.4 2.8 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EME89315.1 - 4.6e-50 169.0 5.9 4.6e-50 169.0 4.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ABC2_membrane PF01061.19 EME89316.1 - 2.2e-30 105.4 27.3 3.4e-30 104.8 18.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EME89316.1 - 1.1e-25 90.4 0.1 1.9e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME89316.1 - 3.3e-08 33.8 0.6 6.3e-06 26.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EME89316.1 - 2.7e-05 23.6 0.1 0.00028 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EME89316.1 - 4.1e-05 22.8 0.1 7.1e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EME89316.1 - 0.00011 22.2 0.0 0.00086 19.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EME89316.1 - 0.00014 21.8 0.1 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EME89316.1 - 0.00072 19.0 0.1 0.0019 17.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EME89316.1 - 0.0027 18.5 0.0 0.0056 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EME89316.1 - 0.0034 16.8 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain SMC_N PF02463.14 EME89316.1 - 0.0069 15.6 0.1 0.026 13.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EME89316.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EME89316.1 - 0.01 15.7 0.1 0.043 13.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EME89316.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EME89316.1 - 0.015 15.4 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EME89316.1 - 0.02 14.6 0.2 0.083 12.6 0.1 2.0 1 1 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EME89316.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME89316.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EME89316.1 - 0.039 14.2 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EME89316.1 - 0.043 13.7 0.1 0.28 11.1 0.0 2.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EME89316.1 - 0.043 12.2 0.4 0.5 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EME89316.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EME89316.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EME89316.1 - 0.095 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 EME89316.1 - 0.19 11.5 0.1 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 TMPIT PF07851.8 EME89316.1 - 0.88 8.5 3.7 1.5 7.7 2.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Aminotran_5 PF00266.14 EME89317.1 - 2.3e-28 98.9 0.0 1.6e-24 86.3 0.0 3.1 1 1 0 1 1 1 1 Aminotransferase class-V His_Phos_2 PF00328.17 EME89318.1 - 1.7e-32 113.1 0.0 2.1e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HEAT PF02985.17 EME89319.1 - 5.6e-22 75.8 9.0 2e-05 24.2 0.2 10.5 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 EME89319.1 - 2.8e-20 72.1 4.2 4e-05 23.9 0.2 8.9 9 1 1 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.1 EME89319.1 - 3.6e-17 62.4 15.8 0.00034 20.8 0.2 8.4 7 2 2 10 10 10 5 HEAT repeats IBN_N PF03810.14 EME89319.1 - 4.2e-11 42.6 2.4 3.1e-10 39.8 0.3 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.8 EME89319.1 - 3.6e-09 36.5 1.0 0.062 13.2 0.0 5.8 4 2 1 5 5 5 3 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 EME89319.1 - 3.9e-08 33.5 0.3 0.51 10.7 0.0 5.7 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EME89319.1 - 2.6e-07 30.2 0.9 0.028 14.2 0.0 6.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EME89319.1 - 9.5e-05 21.8 0.4 5.8 6.1 0.0 5.5 3 2 2 5 5 5 1 CLASP N terminal MMS19_C PF12460.3 EME89319.1 - 0.0032 16.2 0.3 0.0032 16.2 0.2 5.6 4 2 2 6 6 6 2 RNAPII transcription regulator C-terminal Cohesin_HEAT PF12765.2 EME89319.1 - 0.017 15.0 0.1 1.4 8.9 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Rad21_Rec8 PF04824.11 EME89320.1 - 0.0061 15.7 0.1 0.009 15.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PCP_red PF08369.5 EME89320.1 - 0.078 12.8 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Apolipoprotein PF01442.13 EME89321.1 - 0.014 14.9 1.6 1.9 7.9 0.0 2.6 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2730 PF10805.3 EME89321.1 - 0.015 15.0 1.2 0.22 11.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 EME89321.1 - 0.059 12.9 3.1 0.2 11.2 0.1 2.8 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin_2 PF14523.1 EME89321.1 - 3.5 7.6 5.8 5.5 7.0 0.1 3.4 3 2 1 4 4 4 0 Syntaxin-like protein Sec10 PF07393.6 EME89322.1 - 8.2e-207 688.7 0.0 1.1e-206 688.2 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 ApoLp-III PF07464.6 EME89322.1 - 0.071 13.1 1.1 4.5 7.2 0.1 2.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Peptidase_S28 PF05577.7 EME89323.1 - 3.6e-46 157.6 0.2 1.2e-45 155.9 0.2 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 HBS1_N PF08938.5 EME89327.1 - 4.5e-15 55.5 1.3 7.5e-15 54.8 0.9 1.3 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.22 EME89328.1 - 4e-48 163.3 0.1 5.7e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EME89328.1 - 3.4e-08 33.5 0.0 8.1e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EME89328.1 - 6.7e-07 29.2 0.0 1.9e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EME89328.1 - 6.3e-05 23.0 0.2 0.00034 20.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 EME89328.1 - 0.0097 16.4 0.1 0.11 12.9 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EME89328.1 - 0.012 14.8 0.1 1.4 8.1 0.0 2.4 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EME89328.1 - 0.017 14.4 0.3 0.49 9.6 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EME89328.1 - 0.02 14.0 0.0 0.074 12.1 0.0 1.9 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region RII_binding_1 PF10522.4 EME89328.1 - 0.16 12.1 1.2 0.66 10.3 0.8 2.1 1 0 0 1 1 1 0 RII binding domain ArfGap PF01412.13 EME89329.1 - 8.2e-40 135.2 3.3 1.2e-39 134.6 2.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Rootletin PF15035.1 EME89330.1 - 0.03 14.3 0.1 0.033 14.1 0.0 1.0 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SNARE PF05739.14 EME89330.1 - 0.14 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SNARE domain Synaptobrevin PF00957.16 EME89330.1 - 2 8.0 5.4 4.2 7.0 3.2 1.9 1 1 1 2 2 2 0 Synaptobrevin DUF500 PF04366.7 EME89331.1 - 5e-44 148.7 0.1 9.1e-44 147.9 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EME89331.1 - 4.5e-12 45.1 0.1 1.4e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EME89331.1 - 6.5e-12 44.7 0.0 1.9e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EME89331.1 - 3.2e-10 39.4 0.1 3.2e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Erythro-docking PF09277.6 EME89332.1 - 0.0008 19.0 0.1 0.0093 15.6 0.0 2.4 2 0 0 2 2 2 1 Erythronolide synthase, docking Reo_sigmaC PF04582.7 EME89332.1 - 0.0014 17.8 0.4 0.002 17.3 0.3 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EME89332.1 - 0.0035 17.4 0.4 0.0089 16.1 0.2 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EME89332.1 - 0.015 15.5 0.2 3.2 8.0 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EME89332.1 - 0.027 14.3 1.3 0.027 14.3 0.9 1.9 2 1 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 EME89332.1 - 0.062 13.0 0.7 0.15 11.9 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EME89332.1 - 0.38 10.9 7.5 0.044 13.9 1.8 2.0 2 1 0 2 2 2 0 Syntaxin Mnd1 PF03962.10 EME89332.1 - 0.49 10.0 3.1 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Mnd1 family Uso1_p115_C PF04871.8 EME89332.1 - 1.6 8.6 7.1 1.6 8.7 2.2 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region adh_short PF00106.20 EME89333.1 - 6.2e-16 58.7 0.0 1.3e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89333.1 - 3e-15 56.6 0.0 4.4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME89333.1 - 4.3e-06 26.5 0.0 1.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 KR domain dCMP_cyt_deam_1 PF00383.17 EME89334.1 - 1.7e-16 59.7 0.2 2.1e-16 59.3 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EME89334.1 - 1e-10 41.6 1.1 3.4e-09 36.7 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EME89334.1 - 0.00019 20.8 1.8 0.13 11.6 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases SET PF00856.23 EME89335.1 - 3.5e-08 33.9 0.1 0.00014 22.2 0.0 2.9 3 0 0 3 3 3 2 SET domain DDE_Tnp_4 PF13359.1 EME89336.1 - 0.031 13.8 0.0 0.031 13.8 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-FPG_IleRS PF06827.9 EME89337.1 - 0.78 9.4 4.2 47 3.7 2.9 2.4 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS DNA_binding_1 PF01035.15 EME89338.1 - 4.8e-25 87.1 0.0 6.2e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain MFS_1 PF07690.11 EME89339.1 - 4.8e-19 68.2 34.3 8.4e-12 44.4 3.4 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EME89339.1 - 2.2e-07 29.7 5.6 1.2e-06 27.3 0.0 3.0 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like BT1 PF03092.11 EME89339.1 - 0.35 9.5 4.4 0.48 9.0 0.1 2.7 3 0 0 3 3 3 0 BT1 family Dynamin_N PF00350.18 EME89341.1 - 1.6e-14 54.0 0.0 3.1e-13 49.8 0.0 3.1 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EME89341.1 - 4.5e-05 23.3 0.1 0.0011 18.9 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EME89341.1 - 0.00049 20.4 0.4 0.0017 18.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EME89341.1 - 0.0034 16.6 0.0 0.034 13.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IIGP PF05049.8 EME89341.1 - 0.0069 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EME89341.1 - 0.012 16.1 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EME89341.1 - 0.018 14.9 0.1 1 9.3 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AIG1 PF04548.11 EME89341.1 - 0.021 13.9 0.1 0.16 11.0 0.1 2.3 2 0 0 2 2 2 0 AIG1 family AAA_29 PF13555.1 EME89341.1 - 0.037 13.5 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain EAP30 PF04157.11 EME89341.1 - 0.15 11.2 6.0 0.72 8.9 0.3 3.5 4 0 0 4 4 4 0 EAP30/Vps36 family TBPIP PF07106.8 EME89341.1 - 3.4 7.1 14.6 1.2 8.6 1.6 3.3 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EME89341.1 - 5.6 6.7 8.1 17 5.1 0.5 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF87 PF01935.12 EME89341.1 - 6.7 6.4 17.4 0.37 10.5 0.1 4.3 3 2 1 4 4 3 0 Domain of unknown function DUF87 Laminin_II PF06009.7 EME89341.1 - 9 6.0 15.6 2.5 7.8 0.4 4.2 5 0 0 5 5 5 0 Laminin Domain II FAD_binding_7 PF03441.9 EME89343.1 - 3.9e-85 285.4 0.1 5.6e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME89343.1 - 7.4e-37 126.6 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase AMP-binding PF00501.23 EME89344.1 - 7.1e-51 172.9 0.0 1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EME89344.1 - 0.00014 22.7 0.0 0.00047 21.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UAA PF08449.6 EME89345.1 - 6.5e-80 268.2 12.2 2.1e-79 266.5 8.5 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EME89345.1 - 8.1e-10 38.8 24.6 5.7e-05 23.1 7.2 3.5 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EME89345.1 - 0.00027 20.1 2.9 0.079 12.0 0.2 2.4 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EME89345.1 - 0.0099 16.0 25.7 0.046 13.9 2.3 2.7 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EME89345.1 - 0.07 12.7 21.0 0.021 14.4 7.0 3.1 2 2 0 2 2 2 0 Triose-phosphate Transporter family zf-CCCH PF00642.19 EME89346.1 - 0.65 9.7 19.5 0.041 13.5 3.2 3.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) tRNA-synt_1 PF00133.17 EME89347.1 - 2.2e-149 498.2 0.0 2.7e-149 497.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EME89347.1 - 2.8e-22 79.1 0.0 5.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EME89347.1 - 3.4e-20 72.0 0.0 8.1e-10 37.9 0.0 4.2 3 1 1 4 4 4 4 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EME89347.1 - 0.016 14.8 5.3 0.033 13.8 3.7 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EME89347.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 FtsJ PF01728.14 EME89350.1 - 3.1e-59 200.0 0.0 3.9e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.11 EME89351.1 - 3.3e-11 42.5 40.5 1.6e-10 40.2 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily O-antigen_lig PF13425.1 EME89351.1 - 0.0055 16.6 4.2 0.0055 16.6 2.9 3.4 2 1 0 2 2 2 1 O-antigen ligase like membrane protein QCR10 PF09796.4 EME89351.1 - 0.084 12.5 0.1 0.084 12.5 0.1 3.0 3 1 0 4 4 4 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Methyltransf_23 PF13489.1 EME89352.1 - 3e-05 23.7 0.0 3.4e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EME89352.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME89352.1 - 0.0013 19.2 0.0 0.0056 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EME89352.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EME89352.1 - 0.028 14.8 0.0 0.032 14.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EME89352.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Smr PF01713.16 EME89353.1 - 8.2e-09 35.5 0.2 2.3e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Smr domain Ndc1_Nup PF09531.5 EME89354.1 - 2.7 6.3 4.2 3.1 6.1 2.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAD_binding_1 PF00667.15 EME89355.1 - 1.5e-56 191.3 0.0 2.5e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EME89355.1 - 3.3e-12 46.9 0.0 2e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 EME89355.1 - 1.9e-07 31.1 0.0 4.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EME89355.1 - 0.0032 17.3 0.2 0.009 15.9 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 EME89355.1 - 0.04 14.0 0.0 0.7 10.0 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain PTPA PF03095.10 EME89357.1 - 1.2e-111 372.7 0.0 1.3e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PBP_sp32 PF07222.7 EME89359.1 - 0.094 11.8 1.6 0.15 11.2 1.1 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Asparaginase_2 PF01112.13 EME89360.1 - 5.8e-42 143.5 0.6 2e-38 131.8 0.0 3.2 2 2 0 2 2 2 2 Asparaginase Inositol_P PF00459.20 EME89361.1 - 1.5e-52 178.5 0.6 2.9e-52 177.6 0.4 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Gpi16 PF04113.9 EME89362.1 - 8.3e-206 684.3 0.0 1.1e-205 684.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 EME89363.1 - 5.7e-68 229.1 6.8 7.1e-68 228.8 4.7 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF244 PF03112.9 EME89363.1 - 0.21 11.0 1.0 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF GRP PF07172.6 EME89363.1 - 0.55 10.7 27.6 0.17 12.3 16.6 1.9 2 0 0 2 2 2 0 Glycine rich protein family DUF919 PF06034.6 EME89363.1 - 0.8 9.3 4.6 1.4 8.6 0.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) zf-RING_2 PF13639.1 EME89365.1 - 8.5e-11 41.5 7.8 1.2e-10 41.0 5.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EME89365.1 - 7.5e-06 25.9 4.9 1.5e-05 25.0 3.4 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EME89365.1 - 0.00062 19.7 6.6 0.00096 19.1 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EME89365.1 - 0.0022 17.7 2.4 0.0038 17.0 1.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EME89365.1 - 0.0026 17.4 2.9 0.0045 16.6 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EME89365.1 - 0.0057 16.2 5.6 0.01 15.5 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME89365.1 - 0.0074 15.9 2.9 0.012 15.2 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME89365.1 - 0.023 14.4 1.3 0.023 14.4 0.9 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_3 PF14369.1 EME89365.1 - 0.11 12.4 1.7 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger YyzF PF14116.1 EME89365.1 - 0.13 12.2 1.8 0.41 10.6 0.1 2.3 2 0 0 2 2 2 0 YyzF-like protein Rad50_zn_hook PF04423.9 EME89365.1 - 0.18 11.3 1.8 3.4 7.1 0.1 2.6 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EME89365.1 - 1.1 9.1 4.2 2.5 8.0 2.9 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Atx10homo_assoc PF09759.4 EME89366.1 - 9e-24 83.1 0.1 2.5e-23 81.7 0.1 1.8 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Mito_carr PF00153.22 EME89367.1 - 2.7e-56 187.2 2.0 2.2e-20 72.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-Nse PF11789.3 EME89368.1 - 5.4e-23 80.2 0.2 9.3e-23 79.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EME89368.1 - 0.00093 18.8 0.4 0.0033 17.1 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 EME89368.1 - 0.026 14.0 0.8 0.057 12.9 0.5 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger DUF3552 PF12072.3 EME89368.1 - 0.069 12.3 13.2 0.13 11.4 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PspB PF06667.7 EME89368.1 - 0.093 12.6 1.7 0.22 11.4 1.2 1.6 1 0 0 1 1 1 0 Phage shock protein B DUF607 PF04678.8 EME89368.1 - 0.24 11.2 1.9 0.52 10.2 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF724 PF05266.9 EME89368.1 - 0.32 10.5 4.7 0.68 9.5 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF883 PF05957.8 EME89368.1 - 1.7 9.0 10.7 1.5 9.3 5.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 EME89369.1 - 3.8e-28 98.2 31.2 3.8e-28 98.2 21.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF373 PF04123.8 EME89369.1 - 5.5 5.9 5.9 1.7 7.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) ADH_zinc_N PF00107.21 EME89370.1 - 1.1e-24 86.3 0.1 1.8e-24 85.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME89370.1 - 5.1e-21 75.8 0.0 1e-20 74.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME89370.1 - 4e-06 26.5 0.2 9.7e-06 25.3 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LMBR1 PF04791.11 EME89372.1 - 8.3e-31 107.0 3.6 1.1e-30 106.6 2.5 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein IncA PF04156.9 EME89372.1 - 0.068 12.7 0.0 0.068 12.7 0.0 2.5 2 0 0 2 2 2 0 IncA protein DUF4543 PF15076.1 EME89372.1 - 0.19 11.7 0.9 3.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Citrate_synt PF00285.16 EME89373.1 - 7.9e-102 340.6 0.0 9.6e-102 340.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase ICL PF00463.16 EME89375.1 - 6.7e-198 658.1 0.1 7.7e-198 657.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EME89375.1 - 9.4e-11 41.3 0.0 6.5e-10 38.6 0.0 2.2 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EME89375.1 - 0.042 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain HECT PF00632.20 EME89376.1 - 2.1e-82 276.7 0.0 3.2e-82 276.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EME89376.1 - 0.00013 21.6 2.6 0.37 10.6 0.0 6.0 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EME89376.1 - 0.0032 17.4 0.7 0.75 10.0 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 EME89376.1 - 0.39 10.0 3.8 1.2 8.4 0.0 3.1 3 1 0 3 3 3 0 CLASP N terminal RRN3 PF05327.6 EME89376.1 - 7 4.6 8.9 17 3.3 6.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Fe-ADH PF00465.14 EME89377.1 - 1.4e-102 343.1 0.1 1.7e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EME89377.1 - 2.4e-14 53.2 0.0 8.5e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Isochorismatase PF00857.15 EME89378.1 - 6.5e-34 117.3 0.0 7.7e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PEX11 PF05648.9 EME89379.1 - 1.6e-70 236.8 0.6 1.8e-70 236.6 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ATP-synt_E PF05680.7 EME89379.1 - 0.035 14.0 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 ATP synthase E chain Ribosomal_L33 PF00471.15 EME89380.1 - 1.8e-05 24.8 0.0 2.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 CENP-F_leu_zip PF10473.4 EME89381.1 - 0.006 16.4 6.5 0.006 16.4 4.5 7.0 2 2 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CsgE PF10627.4 EME89381.1 - 1.4 8.7 8.9 0.22 11.3 0.2 3.4 3 0 0 3 3 3 0 Curli assembly protein CsgE FlaC_arch PF05377.6 EME89381.1 - 3 7.8 7.4 6.1 6.8 0.1 4.9 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF2636 PF11120.3 EME89382.1 - 0.43 10.1 1.9 0.74 9.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) TraQ PF09679.5 EME89383.1 - 0.0093 15.8 1.9 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) DivIC PF04977.10 EME89383.1 - 0.72 9.3 9.1 14 5.2 0.0 3.4 3 0 0 3 3 3 0 Septum formation initiator Rad21_Rec8_N PF04825.8 EME89385.1 - 7.3e-07 29.1 0.4 5.8e-05 23.0 0.1 2.4 1 1 1 2 2 2 2 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EME89385.1 - 0.0062 15.7 0.1 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein UCH PF00443.24 EME89386.1 - 1.2e-51 175.3 0.0 1.5e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME89386.1 - 1.3e-16 60.9 3.4 4.8e-15 55.7 2.3 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EME89386.1 - 2.6e-09 36.3 0.2 5.9e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EME89386.1 - 0.019 15.1 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain DUF106 PF01956.11 EME89386.1 - 9.3 5.7 5.5 21 4.6 3.8 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 SQS_PSY PF00494.14 EME89390.1 - 2.5e-37 128.6 0.0 3.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Kinesin PF00225.18 EME89392.1 - 3.9e-113 377.5 0.5 8.7e-113 376.4 0.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EME89392.1 - 8.1e-06 26.0 0.1 8.1e-06 26.0 0.1 5.4 6 0 0 6 6 6 1 Kinesin-associated microtubule-binding PSRP-3_Ycf65 PF04839.8 EME89392.1 - 0.1 12.6 0.2 0.1 12.6 0.1 2.8 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) UPF0183 PF03676.9 EME89393.1 - 2.5e-37 128.4 0.0 1.3e-28 99.6 0.0 4.2 3 2 0 3 3 3 3 Uncharacterised protein family (UPF0183) Aminotran_1_2 PF00155.16 EME89394.1 - 2.7e-43 148.3 0.0 3.7e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME89394.1 - 8.6e-07 28.3 0.0 2.4e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EME89394.1 - 7.3e-06 24.5 0.0 1.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EME89394.1 - 0.00041 19.1 0.0 0.00066 18.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EME89394.1 - 0.0024 16.9 0.0 0.0038 16.3 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family F-actin_cap_A PF01267.12 EME89396.1 - 5.2e-86 288.0 0.0 5.9e-86 287.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit 23S_rRNA_IVP PF05635.6 EME89396.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein UCH PF00443.24 EME89397.1 - 5.2e-58 196.2 0.0 7.5e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EME89397.1 - 8.6e-24 84.4 0.0 2.4e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EME89397.1 - 0.00059 20.1 0.0 0.0026 18.0 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain SIP1 PF04938.7 EME89397.1 - 0.0027 17.1 0.1 0.086 12.1 0.1 2.2 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) USP8_dimer PF08969.6 EME89397.1 - 0.071 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain FlhC PF05280.6 EME89397.1 - 0.22 10.9 0.3 0.46 9.9 0.2 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Rubredoxin PF00301.15 EME89397.1 - 0.4 10.5 2.0 1 9.3 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin zf-C2H2_4 PF13894.1 EME89397.1 - 1.5 9.3 4.6 3.6 8.1 1.5 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger VHS PF00790.14 EME89398.1 - 1.5e-40 138.1 0.1 1.5e-40 138.1 0.1 1.7 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EME89398.1 - 2.4e-17 62.5 3.3 4.5e-17 61.7 2.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EME89398.1 - 7.4e-05 21.9 17.3 0.0067 15.9 0.8 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EME89398.1 - 0.0017 18.2 0.9 0.0037 17.1 0.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Ribosomal_S30AE PF02482.14 EME89398.1 - 0.21 12.0 3.4 0.64 10.4 2.3 1.8 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein PEP-utilisers_N PF05524.8 EME89398.1 - 0.82 9.4 5.3 0.57 9.9 1.4 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal zf-C2H2 PF00096.21 EME89399.1 - 5.9e-16 57.7 19.1 0.00011 22.3 1.0 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EME89399.1 - 2.2e-15 56.0 16.8 6e-05 23.1 2.7 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EME89399.1 - 1.2e-14 53.4 18.0 0.00061 19.9 0.6 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 EME89399.1 - 1.7e-05 24.8 17.0 0.0075 16.3 0.9 3.4 1 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EME89399.1 - 0.003 17.6 7.4 0.51 10.4 1.3 2.9 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EME89399.1 - 0.007 16.7 0.5 0.007 16.7 0.3 2.5 2 1 1 3 3 2 1 TRAF-type zinc finger zf-H2C2_5 PF13909.1 EME89399.1 - 0.0096 16.1 2.0 0.0096 16.1 1.4 3.8 5 0 0 5 5 4 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EME89399.1 - 0.012 15.5 0.4 0.012 15.5 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EME89399.1 - 0.031 13.7 0.5 4.3 6.8 0.0 2.8 3 0 0 3 3 2 0 Rad50 zinc hook motif DYW_deaminase PF14432.1 EME89399.1 - 0.071 13.1 0.8 0.11 12.5 0.6 1.4 1 1 0 1 1 1 0 DYW family of nucleic acid deaminases DUF2225 PF09986.4 EME89399.1 - 0.11 11.9 1.4 6.1 6.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-TFIIB PF13453.1 EME89399.1 - 0.13 11.5 1.4 5.1 6.3 0.1 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-LITAF-like PF10601.4 EME89399.1 - 0.14 12.0 7.2 2.2 8.2 5.0 2.3 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-RING_3 PF14369.1 EME89399.1 - 0.19 11.7 8.0 1.3 9.0 0.2 3.0 3 1 0 3 3 3 0 zinc-finger zf-CHY PF05495.7 EME89399.1 - 0.33 11.1 4.3 0.62 10.2 3.0 1.6 1 1 0 1 1 1 0 CHY zinc finger zf-C2HC_2 PF13913.1 EME89399.1 - 0.65 9.7 0.1 0.65 9.7 0.0 4.3 4 2 0 4 4 4 0 zinc-finger of a C2HC-type Cys_rich_CPXG PF14255.1 EME89399.1 - 0.7 9.7 3.4 7 6.5 0.1 2.8 2 1 0 2 2 2 0 Cysteine-rich CPXCG zf-C2H2_jaz PF12171.3 EME89399.1 - 1.2 9.3 14.3 1.6 8.9 0.1 4.6 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 EME89399.1 - 4.6 5.6 6.2 4.8 5.5 0.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF629) Lar_restr_allev PF14354.1 EME89399.1 - 9.2 6.6 6.9 58 4.1 4.8 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar C2 PF00168.25 EME89400.1 - 7.3e-21 73.8 0.1 5.3e-15 55.0 0.0 3.3 3 0 0 3 3 3 2 C2 domain CorA PF01544.13 EME89402.1 - 0.045 12.7 0.1 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Ribosomal_L1 PF00687.16 EME89403.1 - 3.3e-53 180.3 0.7 3.7e-53 180.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.16 EME89405.1 - 1.5e-79 265.2 0.1 1.8e-79 265.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EME89405.1 - 2.9e-14 52.6 0.0 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EME89405.1 - 6.2e-13 48.4 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EME89405.1 - 1.1e-12 47.4 1.6 1.1e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EME89405.1 - 4.8e-11 42.2 0.0 5.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EME89405.1 - 2.3e-08 34.5 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EME89405.1 - 3.7e-06 26.8 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EME89405.1 - 0.007 15.8 0.1 0.057 12.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EME89405.1 - 0.0092 15.0 0.3 0.017 14.2 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EME89405.1 - 0.043 13.6 0.2 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain NARP1 PF12569.3 EME89406.1 - 4.9e-195 649.1 27.7 2.8e-193 643.3 14.3 2.6 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EME89406.1 - 1.1e-18 67.3 26.8 0.0065 16.7 0.8 8.0 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EME89406.1 - 5.8e-14 51.4 40.3 1.5e-05 24.5 0.1 8.7 8 2 3 11 11 10 5 TPR repeat TPR_16 PF13432.1 EME89406.1 - 8.4e-14 51.7 35.5 0.0027 18.3 1.4 9.3 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EME89406.1 - 1.6e-12 46.8 23.8 0.019 15.5 0.0 11.5 7 4 5 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.23 EME89406.1 - 1e-10 40.7 24.5 8.4e-05 22.0 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EME89406.1 - 4.3e-10 38.9 3.7 1.2 9.5 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME89406.1 - 1.3e-09 37.8 25.4 0.033 14.1 0.6 7.9 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EME89406.1 - 1e-08 34.4 47.8 0.0016 18.1 0.0 11.5 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 EME89406.1 - 1.7e-05 24.2 11.2 0.95 9.4 0.0 6.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EME89406.1 - 3e-05 23.7 10.6 0.0051 16.6 0.7 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.7 EME89406.1 - 4.9e-05 23.0 0.3 0.032 14.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EME89406.1 - 0.00013 22.0 0.3 0.47 11.0 0.1 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EME89406.1 - 0.0021 18.3 19.4 17 6.1 0.0 9.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME89406.1 - 0.0026 17.4 15.3 0.039 13.7 0.0 7.6 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 EME89406.1 - 0.0054 16.6 9.8 25 4.9 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat MRF_C2 PF13888.1 EME89406.1 - 0.011 15.5 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Fis1_TPR_C PF14853.1 EME89406.1 - 0.32 10.8 17.8 1.8 8.4 0.0 5.9 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat GN3L_Grn1 PF08701.6 EME89407.1 - 3.3e-26 90.9 14.0 3.3e-26 90.9 9.7 1.7 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase BSP_II PF05432.6 EME89407.1 - 0.0049 16.1 8.1 0.0077 15.5 5.6 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF3246 PF11596.3 EME89407.1 - 0.016 14.4 1.9 0.024 13.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nop14 PF04147.7 EME89407.1 - 0.068 11.0 19.9 0.11 10.4 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EME89408.1 - 0.0077 14.9 6.7 0.011 14.4 4.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1604 PF07713.8 EME89410.1 - 1.2e-39 133.9 3.7 2.6e-39 132.8 1.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EME89410.1 - 2.8e-06 27.0 3.6 1.1e-05 25.1 1.3 2.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EME89410.1 - 0.078 12.8 2.9 0.17 11.7 0.6 2.8 2 1 1 3 3 3 0 DExH-box splicing factor binding site Pkinase PF00069.20 EME89411.1 - 1.3e-77 260.5 0.0 1.9e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89411.1 - 7.4e-40 136.6 0.0 2.1e-39 135.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EME89411.1 - 1.6e-18 65.8 0.1 2.6e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EME89411.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EME89411.1 - 2.8e-05 23.2 0.1 0.00026 20.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EME89411.1 - 0.0022 17.3 1.2 0.0044 16.3 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EME89411.1 - 0.0028 17.4 0.1 0.046 13.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.6 EME89411.1 - 0.028 13.6 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) 2OG-FeII_Oxy_3 PF13640.1 EME89412.1 - 8.2e-05 23.0 0.0 0.00025 21.5 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Daxx PF03344.10 EME89412.1 - 0.0017 16.9 8.3 0.0017 16.9 5.7 2.1 2 0 0 2 2 2 1 Daxx Family DUF1235 PF06822.7 EME89412.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) SDA1 PF05285.7 EME89412.1 - 6.1 6.0 28.0 4.2 6.5 2.8 2.2 2 0 0 2 2 2 0 SDA1 Mitofilin PF09731.4 EME89413.1 - 6.9e-139 464.1 31.2 6.2e-138 461.0 21.6 1.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 EME89413.1 - 0.011 15.7 0.3 0.011 15.7 0.2 2.9 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region COX5A PF02284.11 EME89413.1 - 0.27 11.2 5.5 0.36 10.7 1.1 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase subunit Va CENP-H PF05837.7 EME89413.1 - 1 9.5 17.1 0.73 10.0 0.8 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Atg14 PF10186.4 EME89413.1 - 9.1 5.1 15.6 17 4.2 10.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PCI PF01399.22 EME89415.1 - 2.4e-09 37.4 0.1 2.4e-09 37.4 0.0 2.6 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.17 EME89416.1 - 5.2e-22 77.3 0.1 6.2e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain HLH PF00010.21 EME89417.1 - 0.0018 17.9 0.3 0.0046 16.6 0.2 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sin_N PF04801.8 EME89417.1 - 0.024 13.5 2.4 0.026 13.3 1.7 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF837 PF05769.6 EME89417.1 - 0.13 11.8 3.8 0.34 10.4 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF837) Caudo_TAP PF02413.12 EME89417.1 - 0.17 12.0 3.7 0.19 11.9 2.5 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Glyco_transf_15 PF01793.11 EME89417.1 - 0.18 10.7 3.0 0.21 10.4 2.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase KIAA1430 PF13879.1 EME89417.1 - 0.46 10.9 5.1 5.3 7.5 3.5 2.1 1 1 1 2 2 2 0 KIAA1430 homologue HALZ PF02183.13 EME89417.1 - 0.49 10.1 3.1 0.96 9.2 2.2 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF3506 PF12014.3 EME89418.1 - 1.9e-41 141.0 0.0 3.8e-39 133.5 0.0 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EME89418.1 - 6.7e-08 32.1 1.1 1.1e-07 31.4 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME89418.1 - 4.3e-06 26.2 0.2 7.9e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 F-box domain Adaptin_N PF01602.15 EME89419.1 - 3.5e-142 474.4 0.2 4.1e-142 474.1 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EME89419.1 - 4.3e-22 78.5 0.1 1e-21 77.3 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EME89419.1 - 1e-06 28.9 2.0 0.09 13.0 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EME89419.1 - 5.6e-05 22.8 1.0 3.2 8.0 0.0 4.8 4 1 1 5 5 5 1 HEAT repeat Cnd1 PF12717.2 EME89419.1 - 0.0025 17.6 0.2 0.11 12.3 0.1 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EME89419.1 - 0.019 15.4 0.8 7.7 7.1 0.1 4.5 3 2 2 5 5 5 0 HEAT-like repeat TIP120 PF08623.5 EME89419.1 - 0.029 13.9 0.4 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 EME89419.1 - 0.081 12.7 0.3 72 3.4 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat PTS_2-RNA PF01885.11 EME89420.1 - 8.6e-66 220.7 0.0 1e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF1140 PF06600.6 EME89420.1 - 0.012 15.7 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) TF_Otx PF03529.8 EME89422.1 - 0.0097 16.1 0.2 0.031 14.4 0.1 1.9 1 0 0 1 1 1 1 Otx1 transcription factor Methyltransf_PK PF05891.7 EME89425.1 - 3.4e-74 248.8 0.0 4.2e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EME89425.1 - 3.2e-08 33.4 0.0 4.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EME89425.1 - 4.1e-05 24.1 0.0 0.00015 22.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.1 EME89426.1 - 8.2e-25 88.0 0.0 4.1e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EME89426.1 - 2.9e-13 48.8 0.0 1.7e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EME89426.1 - 1.8e-07 30.4 0.0 0.00016 20.7 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EME89426.1 - 4.4e-07 29.8 0.0 1.3e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EME89426.1 - 0.014 15.1 0.0 1.4 8.6 0.0 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding Arf PF00025.16 EME89427.1 - 2.1e-63 212.7 0.0 2.3e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EME89427.1 - 7.3e-11 41.3 0.0 3.4e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EME89427.1 - 1.1e-07 31.2 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EME89427.1 - 1.9e-06 27.8 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EME89427.1 - 3.6e-06 26.4 0.0 4.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EME89427.1 - 3.8e-06 27.3 0.0 5.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EME89427.1 - 0.00038 19.6 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EME89427.1 - 0.062 12.7 0.0 2.8 7.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EME89427.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DPM2 PF07297.7 EME89428.1 - 1.5e-34 118.1 1.8 1.7e-34 117.9 1.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EME89428.1 - 1.4e-05 24.7 1.7 1.6e-05 24.5 1.2 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EME89428.1 - 0.003 17.4 0.8 0.003 17.4 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) COX14 PF14880.1 EME89428.1 - 0.017 14.7 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4083 PF13314.1 EME89428.1 - 0.025 14.3 0.2 0.025 14.3 0.1 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) DUF1049 PF06305.6 EME89428.1 - 0.033 13.6 0.4 0.033 13.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Permease PF02405.11 EME89428.1 - 0.037 13.4 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Permease Cytochrom_C_asm PF01578.15 EME89428.1 - 0.046 13.2 0.3 0.05 13.1 0.2 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein DiS_P_DiS PF06750.8 EME89428.1 - 0.07 12.9 0.5 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PspC PF04024.7 EME89428.1 - 0.46 9.9 6.5 2.2 7.7 1.0 2.2 2 0 0 2 2 2 0 PspC domain WD40 PF00400.27 EME89429.1 - 9.1e-25 85.5 7.1 3.4e-07 29.8 0.1 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat Nop14 PF04147.7 EME89429.1 - 1.6 6.5 28.2 3.7 5.3 19.5 1.5 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 EME89429.1 - 5.8 6.7 20.8 0.077 12.8 7.1 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.6 EME89429.1 - 8.1 4.4 11.4 14 3.5 7.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rdx PF10262.4 EME89430.1 - 2.3e-27 94.8 0.0 3.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family Eclosion PF04736.7 EME89430.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Spore_III_AB PF09548.5 EME89430.1 - 0.16 11.7 0.3 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TFIIA PF03153.8 EME89431.1 - 9.7 5.9 7.3 14 5.4 5.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Man-6-P_recep PF02157.10 EME89432.1 - 9.1e-08 31.4 0.1 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EME89432.1 - 1.3e-07 31.5 0.1 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EME89432.1 - 3.2e-05 23.3 0.1 8.8e-05 21.8 0.1 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 NrfD_2 PF14589.1 EME89432.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysulfide reductase NADH-u_ox-rdase PF10785.4 EME89432.1 - 0.2 11.9 0.9 0.59 10.4 0.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DAO PF01266.19 EME89434.1 - 7.9e-47 159.8 0.0 9.1e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EME89434.1 - 1.9e-08 34.4 0.0 0.0041 17.0 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME89434.1 - 1e-07 31.8 0.1 0.0005 19.8 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EME89434.1 - 6.7e-07 29.5 0.1 6.6e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME89434.1 - 1.2e-05 24.3 0.1 0.00018 20.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EME89434.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME89434.1 - 0.00014 20.9 0.1 0.0046 15.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EME89434.1 - 0.00035 19.3 0.4 0.0052 15.4 0.2 2.1 1 1 0 1 1 1 1 Tryptophan halogenase Saccharop_dh PF03435.13 EME89434.1 - 0.0012 17.9 0.1 0.064 12.2 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 EME89434.1 - 0.003 17.9 0.0 0.049 14.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EME89434.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EME89434.1 - 0.0078 16.2 0.0 0.045 13.7 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EME89434.1 - 0.036 13.0 0.0 0.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EME89434.1 - 0.037 12.8 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EME89434.1 - 0.044 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 EME89434.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EME89434.1 - 0.13 10.6 0.2 1.1 7.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 EME89435.1 - 5e-08 32.1 0.1 1e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME89435.1 - 1.1e-07 31.5 11.0 2.6e-07 30.4 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase PF00756.15 EME89436.1 - 2.2e-53 181.2 0.0 2.6e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EME89436.1 - 1.5e-07 31.2 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME89436.1 - 0.00015 21.7 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EME89436.1 - 0.0016 17.7 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EME89436.1 - 0.0052 16.0 0.2 0.031 13.5 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.4 EME89436.1 - 0.0075 15.5 0.0 0.082 12.1 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EME89436.1 - 0.01 15.3 0.0 0.19 11.3 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EME89436.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EME89436.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EME89436.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EME89436.1 - 0.041 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EME89436.1 - 0.079 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpb6 PF01192.17 EME89437.1 - 7.5e-23 80.0 0.1 1e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Adeno_Penton_B PF01686.12 EME89437.1 - 0.03 12.5 0.0 0.034 12.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein zf-C2H2 PF00096.21 EME89438.1 - 3e-23 80.6 40.4 1.8e-05 24.7 0.2 10.5 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EME89438.1 - 8.1e-21 72.7 34.3 0.0044 17.2 0.2 9.7 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EME89438.1 - 8.7e-17 60.4 35.7 8.1e-06 25.8 0.2 9.6 9 0 0 9 9 9 5 Zinc-finger double domain zf-met PF12874.2 EME89438.1 - 0.00024 21.1 3.9 17 5.8 0.3 6.1 7 0 0 7 7 7 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EME89438.1 - 0.046 13.8 16.8 1.6 8.9 0.0 6.7 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EME89438.1 - 1.2 9.2 14.6 6.2 6.9 0.5 4.7 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 EME89438.1 - 1.9 6.9 6.7 14 4.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF629) Aminotran_5 PF00266.14 EME89439.1 - 1.6e-95 320.0 0.0 2.5e-95 319.3 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EME89439.1 - 1.8e-07 30.4 0.0 2.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EME89439.1 - 2.5e-07 30.1 0.0 3.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EME89439.1 - 0.00021 20.4 0.0 0.00085 18.4 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EME89439.1 - 0.0073 14.6 0.0 0.012 13.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 EME89439.1 - 0.024 13.1 0.0 0.034 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 EME89440.1 - 1.6e-57 194.6 9.3 2.1e-57 194.3 6.4 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EME89440.1 - 2.2e-14 52.5 0.6 4.6e-14 51.5 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EME89440.1 - 2.7e-12 46.0 0.2 5.1e-12 45.1 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EME89440.1 - 1.3e-09 37.3 0.1 3.2e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Sugar_tr PF00083.19 EME89441.1 - 3.1e-28 98.5 25.5 3.6e-22 78.5 8.9 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EME89441.1 - 7.3e-28 97.2 35.2 6.4e-23 81.0 9.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EME89441.1 - 0.0035 16.1 0.7 0.0066 15.1 0.5 1.5 1 0 0 1 1 1 1 BT1 family PIRT PF15099.1 EME89441.1 - 0.061 12.5 1.7 0.069 12.3 0.1 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family MFS_1 PF07690.11 EME89442.1 - 3.7e-22 78.5 57.7 2.2e-13 49.6 17.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Mito_fiss_reg PF05308.6 EME89442.1 - 5.2 6.3 6.2 7.7 5.8 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Peroxidase_2 PF01328.12 EME89444.1 - 2e-15 56.2 0.6 6.1e-15 54.6 0.4 1.7 1 1 0 1 1 1 1 Peroxidase, family 2 Peptidase_A22B PF04258.8 EME89445.1 - 1.4e-59 202.0 1.0 8e-59 199.5 0.7 1.9 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EME89445.1 - 3.5e-09 36.1 0.5 3.5e-09 36.1 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1119) PBP1_TM PF14812.1 EME89445.1 - 0.006 16.8 0.0 0.006 16.8 0.0 2.5 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 EME89445.1 - 0.19 11.4 3.1 0.82 9.3 0.0 2.5 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.12 EME89445.1 - 9.3 4.9 10.8 0.57 8.9 0.4 3.1 3 0 0 3 3 3 0 Presenilin FA_desaturase PF00487.19 EME89446.1 - 3e-25 89.1 19.3 6.4e-25 88.0 13.4 1.5 1 1 0 1 1 1 1 Fatty acid desaturase ATP-grasp_4 PF13535.1 EME89448.1 - 3.1e-13 49.8 0.0 7.4e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EME89448.1 - 5.7e-08 31.8 0.0 2.3e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EME89448.1 - 2.5e-05 24.2 0.0 5.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain MFS_1 PF07690.11 EME89449.1 - 3.7e-43 147.5 31.9 4.8e-37 127.4 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SdpI PF13630.1 EME89449.1 - 0.004 16.8 0.5 0.004 16.8 0.4 4.9 6 1 2 8 8 8 1 SdpI/YhfL protein family Dabb PF07876.7 EME89450.1 - 7.3e-22 77.6 0.0 8.2e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.15 EME89451.1 - 1.6e-19 69.8 0.0 2.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pneumo_phosprot PF02478.11 EME89451.1 - 0.79 9.2 5.7 1.1 8.7 3.9 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein TIP49 PF06068.8 EME89452.1 - 3.6e-175 582.4 0.2 4.2e-174 578.9 0.1 1.9 1 1 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EME89452.1 - 5.3e-12 46.0 0.1 2.6e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EME89452.1 - 4e-10 39.1 0.1 8.2e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EME89452.1 - 5.4e-06 26.5 0.1 0.00028 20.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EME89452.1 - 3.5e-05 23.4 0.1 0.00016 21.3 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EME89452.1 - 4.9e-05 23.4 0.1 0.3 11.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EME89452.1 - 0.00026 20.9 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME89452.1 - 0.0006 19.5 0.2 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EME89452.1 - 0.0011 18.5 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EME89452.1 - 0.0012 18.2 0.1 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME89452.1 - 0.0015 17.6 1.1 0.0036 16.4 0.5 1.7 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 EME89452.1 - 0.0067 15.6 0.1 0.39 9.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EME89452.1 - 0.0084 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EME89452.1 - 0.019 14.4 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EME89452.1 - 0.068 12.2 0.1 0.2 10.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 EME89452.1 - 0.073 13.3 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EME89452.1 - 0.08 13.7 0.0 0.2 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EME89452.1 - 0.097 11.5 0.3 0.38 9.6 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DnaB_C PF03796.10 EME89452.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IBR PF01485.16 EME89453.1 - 2.7e-10 39.9 5.6 2.7e-10 39.9 3.9 3.3 3 1 0 3 3 3 2 IBR domain P5CR_dimer PF14748.1 EME89454.1 - 8.2e-27 93.3 3.2 1.5e-26 92.5 2.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EME89454.1 - 2.1e-08 34.4 0.0 7.6e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PTR2 PF00854.16 EME89455.1 - 8.9e-26 90.5 9.7 9.8e-24 83.8 6.7 2.3 1 1 0 1 1 1 1 POT family DIOX_N PF14226.1 EME89456.1 - 1.3e-21 77.3 0.0 2.5e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME89456.1 - 1.9e-14 53.7 0.0 3.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 EME89457.1 - 4.4e-301 997.1 0.3 3.3e-80 269.5 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EME89457.1 - 8.8e-156 517.3 0.0 2.8e-40 138.0 0.0 5.6 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 EME89457.1 - 5.7e-51 170.6 1.4 1.2e-11 44.6 0.0 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EME89457.1 - 2.9e-16 60.1 1.8 0.00045 21.1 0.0 5.1 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EME89457.1 - 0.0095 14.5 0.2 2.9 6.3 0.0 2.8 3 0 0 3 3 3 2 GH3 auxin-responsive promoter FAM91_C PF14648.1 EME89457.1 - 0.045 12.5 0.0 0.094 11.5 0.0 1.4 1 0 0 1 1 1 0 FAM91 C-terminus DUF2407_C PF13373.1 EME89459.1 - 3.6e-38 130.6 0.2 5.5e-38 130.0 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EME89459.1 - 6.7e-25 87.1 0.0 1.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EME89459.1 - 0.0015 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EME89459.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TRAUB PF08164.7 EME89460.1 - 1.1e-30 105.5 5.3 1.3e-30 105.3 0.2 3.1 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EME89460.1 - 1.1e-25 90.2 2.2 1.1e-25 90.2 1.5 2.3 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor IBR PF01485.16 EME89461.1 - 7.2e-13 48.2 17.6 3.8e-08 33.0 4.0 4.8 4 2 0 4 4 4 2 IBR domain Mg_trans_NIPA PF05653.9 EME89464.1 - 3.8e-18 65.4 4.3 6.2e-18 64.7 3.0 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EME89464.1 - 6e-05 23.0 0.4 6e-05 23.0 0.3 3.3 2 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EME89464.1 - 0.0096 16.1 0.6 0.0096 16.1 0.4 3.3 2 1 2 4 4 4 1 Multidrug resistance efflux transporter vATP-synt_E PF01991.13 EME89465.1 - 1.3e-59 200.8 13.4 1.7e-59 200.4 9.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit HSP33 PF01430.14 EME89465.1 - 0.017 14.2 1.0 0.024 13.7 0.7 1.2 1 0 0 1 1 1 0 Hsp33 protein IBB PF01749.15 EME89465.1 - 0.34 11.1 9.5 1.4 9.1 0.5 2.4 2 0 0 2 2 2 0 Importin beta binding domain Abhydrolase_3 PF07859.8 EME89466.1 - 3.3e-20 72.5 0.0 3.3e-19 69.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EME89466.1 - 1.1e-07 31.2 0.0 0.00024 20.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EME89466.1 - 4.6e-07 29.6 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME89466.1 - 0.00035 19.5 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EME89466.1 - 0.0028 16.4 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 EME89466.1 - 0.0033 16.1 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.7 EME89466.1 - 0.019 13.4 0.0 0.87 8.0 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 EME89466.1 - 0.028 13.0 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF2048 PF09752.4 EME89466.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Glyco_tran_WbsX PF14307.1 EME89467.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase WbsX DUF663 PF04950.7 EME89469.1 - 4.7e-96 321.2 0.0 7e-96 320.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EME89469.1 - 1.9e-18 65.7 0.0 4.1e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain IER PF05760.7 EME89470.1 - 0.22 11.4 2.2 0.22 11.4 1.5 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) GAGA_bind PF06217.7 EME89470.1 - 0.25 11.2 4.0 0.29 11.0 2.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RP-C_C PF11800.3 EME89470.1 - 0.39 10.3 2.5 0.52 9.9 1.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region TFIIF_alpha PF05793.7 EME89470.1 - 0.44 8.8 21.9 0.52 8.6 15.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ATC_hydrolase PF14196.1 EME89470.1 - 0.46 10.8 4.3 0.59 10.5 3.0 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase CDC27 PF09507.5 EME89470.1 - 0.76 8.9 15.4 0.91 8.6 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TALPID3 PF15324.1 EME89470.1 - 1.1 6.5 7.8 1.4 6.1 5.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Hid1 PF12722.2 EME89470.1 - 1.5 6.4 3.9 1.9 6.0 2.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.6 EME89470.1 - 2.6 7.5 13.3 3 7.3 9.3 1.1 1 0 0 1 1 1 0 PPP4R2 Eapp_C PF10238.4 EME89470.1 - 2.7 7.8 7.9 7.3 6.4 5.5 1.7 1 1 0 1 1 1 0 E2F-associated phosphoprotein Peptidase_S8 PF00082.17 EME89472.1 - 1.2e-25 90.2 2.1 1.3e-25 90.1 1.5 1.1 1 0 0 1 1 1 1 Subtilase family Herpes_gE PF02480.11 EME89473.1 - 0.0049 15.1 0.0 0.0051 15.1 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EME89473.1 - 0.064 12.9 0.8 0.086 12.5 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF1191 PF06697.7 EME89473.1 - 0.075 11.8 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1180 PF06679.7 EME89473.1 - 0.087 12.7 0.4 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Rifin_STEVOR PF02009.11 EME89473.1 - 0.17 11.5 0.2 0.21 11.1 0.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family TYW3 PF02676.9 EME89474.1 - 3e-64 215.9 0.0 3.9e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PAS_9 PF13426.1 EME89475.1 - 1.1e-18 67.5 0.0 4.8e-17 62.2 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EME89475.1 - 2.8e-06 27.1 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EME89475.1 - 0.013 15.5 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold DUF3659 PF12396.3 EME89476.1 - 8.3e-14 51.0 0.4 1.7e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) DNA_pol_A_exo1 PF01612.15 EME89476.1 - 0.002 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF4574 PF15141.1 EME89477.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) LRR_4 PF12799.2 EME89478.1 - 5.5e-15 54.6 4.7 5e-07 29.2 0.1 5.3 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EME89478.1 - 1.4e-11 43.9 4.2 9.9e-07 28.4 0.1 4.6 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 EME89478.1 - 8.6e-08 31.9 0.1 0.0043 16.6 0.0 3.2 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.1 EME89478.1 - 0.00019 21.1 1.6 21 5.5 0.0 5.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EME89478.1 - 0.0018 18.1 2.4 21 5.9 0.1 6.2 8 0 0 8 8 8 1 Leucine rich repeat LRR_1 PF00560.28 EME89478.1 - 0.002 17.8 7.0 6.4 7.2 0.1 6.3 6 1 0 6 6 6 1 Leucine Rich Repeat Abhydro_lipase PF04083.11 EME89478.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Apq12 PF12716.2 EME89479.1 - 6.9e-15 54.4 9.2 1.1e-14 53.7 6.4 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis SRP-alpha_N PF04086.8 EME89480.1 - 5.2e-57 193.3 7.0 6.3e-56 189.8 4.8 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EME89480.1 - 2.7e-44 150.9 0.6 1e-43 149.0 0.4 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EME89480.1 - 1.2e-07 31.7 0.1 3.4e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EME89480.1 - 0.00019 20.3 0.0 0.00038 19.3 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EME89480.1 - 0.001 18.5 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EME89480.1 - 0.0069 16.3 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Fer4_NifH PF00142.13 EME89480.1 - 0.014 14.6 0.0 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.9 EME89480.1 - 0.015 15.0 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EME89480.1 - 0.021 14.9 0.3 0.16 12.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 EME89480.1 - 0.043 13.7 0.1 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain CinA PF02464.12 EME89480.1 - 0.044 13.2 0.1 0.093 12.1 0.1 1.5 1 0 0 1 1 1 0 Competence-damaged protein AAA_10 PF12846.2 EME89480.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA-like domain YIF1 PF03878.10 EME89481.1 - 1.3e-72 243.8 2.2 1.5e-72 243.6 1.5 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EME89481.1 - 0.00027 20.4 2.9 0.00027 20.4 2.0 1.7 2 0 0 2 2 2 1 Yip1 domain TPR_12 PF13424.1 EME89482.1 - 2.2e-15 56.3 6.3 8.5e-07 28.8 0.3 4.9 1 1 3 5 5 5 3 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EME89482.1 - 6.2e-14 51.5 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_10 PF13374.1 EME89482.1 - 4.8e-12 45.3 12.9 6.6e-06 25.8 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.17 EME89482.1 - 7.6e-07 28.2 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EME89482.1 - 1.8e-05 24.8 0.2 0.00014 21.8 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EME89482.1 - 7.9e-05 22.8 0.2 0.00064 19.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain TPR_14 PF13428.1 EME89482.1 - 0.01 16.4 0.6 10 7.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Mur_ligase_M PF08245.7 EME89483.1 - 5.4e-06 26.5 0.0 0.28 11.1 0.0 3.2 3 1 0 3 3 3 2 Mur ligase middle domain Kelch_5 PF13854.1 EME89485.1 - 8.6e-12 44.7 22.3 2.8e-09 36.7 0.1 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 EME89485.1 - 2.6e-07 30.2 20.5 0.0029 17.3 0.4 6.4 5 2 2 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EME89485.1 - 1.1e-06 28.1 11.4 0.042 13.6 0.0 5.5 6 0 0 6 6 5 3 Kelch motif SKG6 PF08693.5 EME89485.1 - 1.4e-05 24.2 0.9 2.9e-05 23.3 0.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.1 EME89485.1 - 7.5e-05 22.7 15.5 0.013 15.6 0.2 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EME89485.1 - 0.00014 21.8 19.4 0.45 10.7 0.3 6.0 6 0 0 6 6 5 2 Kelch motif DUF1191 PF06697.7 EME89485.1 - 0.00042 19.2 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Kelch_1 PF01344.20 EME89485.1 - 0.0013 18.2 14.5 0.2 11.2 0.3 5.6 6 0 0 6 6 6 2 Kelch motif EphA2_TM PF14575.1 EME89485.1 - 0.0045 17.3 0.0 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EME89485.1 - 0.0091 14.3 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 EME89485.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protocadherin CCSMST1 PF15013.1 EME89485.1 - 0.031 14.1 0.1 61 3.6 0.0 3.4 3 0 0 3 3 3 0 CCSMST1 family PDGLE PF13190.1 EME89485.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 PDGLE domain Shisa PF13908.1 EME89485.1 - 0.073 13.2 1.3 0.16 12.1 0.9 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 EME89485.1 - 0.1 12.2 0.3 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.8 EME89485.1 - 0.67 9.4 3.2 1.6 8.2 2.2 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF1977 PF09320.6 EME89486.1 - 1.4 9.2 4.5 21 5.4 1.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1977) adh_short PF00106.20 EME89488.1 - 8.4e-19 68.0 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME89488.1 - 9.2e-10 38.4 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME89488.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EME89488.1 - 9.1e-05 22.5 0.1 0.00014 21.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EME89488.1 - 0.00054 18.9 0.0 0.00071 18.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EME89488.1 - 0.0021 17.0 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EME89488.1 - 0.023 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3940 PF13076.1 EME89488.1 - 0.17 11.4 0.8 0.33 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) NAC PF01849.13 EME89489.1 - 1.4e-21 75.7 0.3 2.3e-21 75.0 0.2 1.4 1 0 0 1 1 1 1 NAC domain Dehydratase_hem PF13816.1 EME89490.1 - 9.7e-91 304.0 0.2 1.1e-90 303.8 0.2 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EME89490.1 - 1.4e-08 34.8 1.1 7.8e-05 22.7 0.4 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Acetyltransf_1 PF00583.19 EME89491.1 - 9.7e-07 28.7 0.1 2.5e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EME89491.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EME89491.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME89491.1 - 0.02 14.7 0.1 4.4 7.1 0.0 2.5 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME89491.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltransf_11 PF08241.7 EME89494.1 - 0.0028 18.0 0.0 0.006 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EME89494.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family NHR2 PF08788.6 EME89494.1 - 0.2 11.1 0.3 0.49 9.9 0.2 1.5 1 0 0 1 1 1 0 NHR2 domain like MIF4G PF02854.14 EME89495.1 - 3.1e-26 92.0 1.9 4.9e-26 91.4 1.3 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EME89495.1 - 7.5e-22 77.1 0.1 3e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 MA3 domain Prefoldin_3 PF13758.1 EME89496.1 - 4.8e-19 67.9 0.2 1.5e-18 66.3 0.1 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EME89496.1 - 3.4e-14 53.5 0.5 3.4e-14 53.5 0.3 5.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.15 EME89496.1 - 0.0025 17.5 8.8 0.31 10.8 0.6 3.4 4 0 0 4 4 4 2 Prefoldin subunit YqjK PF13997.1 EME89496.1 - 0.15 12.2 1.0 0.53 10.5 0.2 2.3 2 0 0 2 2 2 0 YqjK-like protein MerR-DNA-bind PF09278.6 EME89496.1 - 6.8 7.1 8.0 37 4.8 0.0 4.1 4 0 0 4 4 4 0 MerR, DNA binding zf-C2H2_2 PF12756.2 EME89497.1 - 5.5e-36 122.7 10.7 1.2e-29 102.3 2.5 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EME89497.1 - 4.2e-08 33.0 17.0 0.0032 17.5 0.1 3.9 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EME89497.1 - 0.00071 19.6 2.3 0.00071 19.6 1.6 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type DUF2407 PF10302.4 EME89497.1 - 0.0095 16.1 0.1 0.022 14.9 0.1 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain SnoaL_2 PF12680.2 EME89497.1 - 0.038 14.3 0.2 0.038 14.3 0.1 2.2 3 0 0 3 3 3 0 SnoaL-like domain zf-C2H2 PF00096.21 EME89497.1 - 0.052 13.9 31.5 0.75 10.2 0.5 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF581 PF04570.9 EME89497.1 - 0.71 9.2 5.1 11 5.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF581) zf-C2H2_6 PF13912.1 EME89497.1 - 1.3 9.0 10.5 0.4 10.6 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF572 PF04502.8 EME89498.1 - 1.4e-46 159.1 0.9 1.7e-46 158.9 0.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Carboxyl_trans PF01039.17 EME89498.1 - 0.19 10.0 1.7 0.25 9.6 1.2 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain Striatin PF08232.7 EME89498.1 - 1.2 9.4 8.4 0.16 12.2 1.8 2.0 1 1 1 2 2 2 0 Striatin family SNF2_N PF00176.18 EME89499.1 - 1.9e-64 217.3 0.0 2.9e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EME89499.1 - 6.7e-18 64.5 0.0 1.4e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EME89499.1 - 1.2e-11 44.2 5.5 2.5e-11 43.2 3.8 1.6 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EME89499.1 - 4e-10 39.3 0.0 9.8e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EME89499.1 - 1.5e-09 37.3 6.8 3.6e-09 36.1 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EME89499.1 - 2.6e-09 36.9 6.5 2.6e-09 36.9 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME89499.1 - 3.1e-08 33.1 4.1 3.1e-08 33.1 2.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EME89499.1 - 1.8e-07 30.8 5.5 4.5e-07 29.6 3.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EME89499.1 - 3.8e-07 30.1 3.7 1.2e-06 28.4 2.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EME89499.1 - 1.3e-06 27.7 2.0 1.7e-05 24.2 2.2 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EME89499.1 - 3.5e-06 26.6 5.1 7.5e-06 25.5 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EME89499.1 - 1.2e-05 24.9 3.5 2.9e-05 23.6 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 EME89499.1 - 0.00099 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain DEAD PF00270.24 EME89499.1 - 0.0027 17.2 0.0 0.0072 15.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-Apc11 PF12861.2 EME89499.1 - 0.0032 17.2 0.7 0.0081 15.9 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EME89499.1 - 0.0092 15.7 2.0 0.0092 15.7 1.4 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EME89499.1 - 0.018 14.6 3.2 0.044 13.3 2.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Copper-fist PF00649.13 EME89500.1 - 2e-18 65.3 0.7 2e-18 65.3 0.5 3.2 3 1 1 4 4 4 2 Copper fist DNA binding domain Glyco_hydro_cc PF11790.3 EME89501.1 - 3.5e-31 108.4 0.1 9.1e-31 107.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.13 EME89502.1 - 2.8e-09 36.7 9.2 2.8e-09 36.7 6.4 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EME89502.1 - 4.9e-08 32.1 0.1 8e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CCDC92 PF14916.1 EME89502.1 - 0.05 13.2 3.6 0.098 12.2 2.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function adh_short PF00106.20 EME89503.1 - 7.8e-23 81.2 0.9 1.3e-22 80.4 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89503.1 - 3.9e-14 53.0 0.1 7.2e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME89503.1 - 1.6e-08 34.4 3.7 4.5e-08 32.9 2.5 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EME89503.1 - 0.0043 17.0 0.9 0.0079 16.2 0.6 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME89503.1 - 0.0076 15.7 0.4 0.013 14.9 0.2 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 EME89503.1 - 0.095 13.1 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PRMT5 PF05185.11 EME89503.1 - 0.12 11.2 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CDC27 PF09507.5 EME89504.1 - 0.91 8.6 19.0 1.3 8.1 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 EME89504.1 - 7.9 4.5 18.3 10 4.1 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1522 PF07482.6 EME89505.1 - 0.0077 16.3 0.7 0.0089 16.1 0.5 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1522) DUF1547 PF07577.6 EME89505.1 - 0.099 12.3 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) PRCC PF10253.4 EME89505.1 - 0.15 12.7 3.5 0.18 12.5 2.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Paramyxo_C PF01692.13 EME89505.1 - 0.29 10.7 3.3 0.38 10.3 2.3 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Flavokinase PF01687.12 EME89506.1 - 2.3e-38 130.8 0.0 3e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 EME89507.1 - 0.00045 19.9 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EME89507.1 - 0.088 12.7 12.0 0.02 14.7 6.0 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EME89508.1 - 2.8e-26 92.0 40.2 3.3e-26 91.8 22.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EME89508.1 - 2.2e-07 29.4 0.3 3e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FF PF01846.14 EME89509.1 - 5.8e-07 29.3 0.1 5.8e-07 29.3 0.1 4.2 5 0 0 5 5 5 1 FF domain Proteasome PF00227.21 EME89510.1 - 2.8e-61 206.1 0.2 3.4e-61 205.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EME89510.1 - 3.6e-14 51.7 0.2 7e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EME89510.1 - 0.061 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit GXWXG PF14231.1 EME89511.1 - 0.094 12.3 0.1 17 5.1 0.1 2.5 2 0 0 2 2 2 0 GXWXG protein Peptidase_C14 PF00656.17 EME89512.1 - 1.2e-42 146.3 0.0 1.6e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Ferritin PF00210.19 EME89512.1 - 0.099 12.4 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain DUF1590 PF07629.6 EME89513.1 - 0.18 11.4 0.9 0.25 10.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) Dfp1_Him1_M PF08630.5 EME89514.1 - 7.2e-41 138.8 0.0 1.7e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EME89514.1 - 7.6e-25 86.3 0.4 1.4e-24 85.4 0.3 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EME89514.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EME89514.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain APG12 PF04110.8 EME89515.1 - 1.9e-24 85.6 0.7 2.1e-24 85.5 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 Pantoate_transf PF02548.10 EME89516.1 - 3.6e-102 340.9 0.1 4.3e-102 340.7 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EME89516.1 - 3.7e-09 36.1 2.2 7.8e-09 35.0 0.1 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NanE PF04131.9 EME89516.1 - 0.2 10.6 2.1 5.8 5.8 0.4 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PA PF02225.17 EME89516.1 - 0.84 9.3 4.6 4.4 7.0 0.5 2.9 2 1 1 3 3 3 0 PA domain Pkinase PF00069.20 EME89517.1 - 1.1e-59 201.7 0.0 1.5e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89517.1 - 6e-31 107.4 0.0 8.2e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EME89517.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EME89517.1 - 0.0036 17.0 2.0 0.0087 15.8 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EME89517.1 - 0.0039 16.2 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EME89518.1 - 7e-38 129.2 0.1 8.7e-38 128.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M24 PF00557.19 EME89519.1 - 2.3e-47 161.2 0.1 9.1e-47 159.3 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EME89519.1 - 6.2e-38 129.2 0.0 1.8e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain SIR2 PF02146.12 EME89520.1 - 9.1e-37 126.4 0.0 2e-36 125.3 0.0 1.5 1 1 0 1 1 1 1 Sir2 family UCH_1 PF13423.1 EME89521.1 - 7.4e-51 173.3 0.3 1e-50 172.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EME89521.1 - 3.2e-21 76.3 0.0 5.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Exonuclease PQQ_2 PF13360.1 EME89521.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain PEPCK_ATP PF01293.15 EME89522.1 - 2.1e-217 722.2 0.0 2.4e-217 722.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 EME89522.1 - 0.014 14.7 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EME89522.1 - 0.037 14.3 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EME89522.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EME89522.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PHY PF00360.15 EME89523.1 - 1.3e-27 96.0 0.0 5.8e-27 94.0 0.0 2.0 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.21 EME89523.1 - 2.1e-16 59.6 0.2 7.1e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EME89523.1 - 2.1e-15 56.6 0.0 7.9e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EME89523.1 - 9.2e-15 55.0 0.0 3.3e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EME89523.1 - 5.7e-13 48.6 0.5 1.9e-12 46.9 0.4 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EME89523.1 - 7.1e-11 42.5 0.0 2.2e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold Pro_isomerase PF00160.16 EME89524.1 - 1.1e-51 175.1 0.0 1.2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ADH_N PF08240.7 EME89525.1 - 3.3e-27 94.3 0.5 6.8e-27 93.3 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EME89525.1 - 4.6e-08 32.6 0.4 8.4e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EME89525.1 - 0.00025 20.6 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EME89525.1 - 0.00086 17.8 0.5 0.0033 15.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EME89525.1 - 0.071 11.9 0.8 0.11 11.3 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EME89525.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME89525.1 - 0.15 11.0 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain ECH PF00378.15 EME89526.1 - 1.3e-28 99.8 0.2 1.4e-28 99.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PAF-AH_p_II PF03403.8 EME89527.1 - 2.4e-40 138.0 0.0 2.3e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EME89527.1 - 3.5e-14 52.7 0.0 8.3e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EME89527.1 - 2.9e-11 43.7 0.0 6.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EME89527.1 - 1.2e-06 27.6 0.1 6.3e-06 25.2 0.1 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EME89527.1 - 6.9e-05 22.6 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EME89527.1 - 0.0014 18.2 0.0 0.0035 16.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EME89527.1 - 0.014 14.2 0.1 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.16 EME89527.1 - 0.017 14.3 0.1 0.93 8.6 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EME89527.1 - 0.059 12.9 0.1 0.53 9.8 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EME89527.1 - 0.16 11.3 0.0 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Fringe PF02434.11 EME89528.1 - 8.9e-05 21.8 0.2 0.0033 16.6 0.0 2.9 3 1 0 3 3 3 1 Fringe-like Galactosyl_T PF01762.16 EME89528.1 - 0.069 12.7 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Galactosyltransferase bZIP_1 PF00170.16 EME89529.1 - 3.4e-09 36.5 8.8 4.6e-09 36.1 6.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME89529.1 - 3.5e-06 26.7 11.3 4.6e-06 26.3 7.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EME89529.1 - 0.0099 16.1 4.3 0.014 15.6 3.0 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor ATG16 PF08614.6 EME89529.1 - 0.015 15.1 0.4 0.016 15.0 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TEX13 PF15186.1 EME89529.1 - 0.06 12.9 0.3 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Cep57_MT_bd PF06657.8 EME89529.1 - 0.084 12.8 0.1 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF605 PF04652.11 EME89529.1 - 1.4 8.2 14.2 1.6 8.0 9.8 1.0 1 0 0 1 1 1 0 Vta1 like WD40_alt PF14077.1 EME89529.1 - 1.9 8.1 5.7 10 5.8 0.1 2.2 1 1 1 2 2 2 0 Alternative WD40 repeat motif AflR PF08493.5 EME89529.1 - 3.5 6.5 13.4 4.5 6.2 9.3 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Herpes_DNAp_acc PF04929.7 EME89529.1 - 3.6 6.4 6.9 4.7 6.0 4.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TPP1 PF10341.4 EME89530.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Telomere_Sde2 PF13019.1 EME89532.1 - 7.8e-63 210.9 0.8 7.8e-63 210.9 0.5 1.8 2 0 0 2 2 2 1 Telomere stability and silencing Moulting_cycle PF04870.11 EME89532.1 - 0.035 13.1 5.8 0.05 12.6 4.1 1.2 1 0 0 1 1 1 0 Moulting cycle HXXSHH PF07586.6 EME89532.1 - 0.54 9.1 3.2 0.74 8.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF1675 PF07897.6 EME89532.1 - 0.65 9.8 14.6 0.27 11.0 8.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) S10_plectin PF03501.10 EME89533.1 - 1.8e-41 139.8 0.2 2.2e-41 139.6 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 EME89534.1 - 4.3e-24 85.0 0.1 6.2e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EME89534.1 - 1.5e-06 27.8 0.1 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EME89534.1 - 0.0054 16.4 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Acetyltransf_7 PF13508.1 EME89535.1 - 3.1e-08 33.6 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EME89535.1 - 2.4e-07 30.6 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EME89535.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EME89535.1 - 0.00019 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 EME89536.1 - 7.1e-13 48.2 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EME89536.1 - 1e-05 25.2 0.0 2.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EME89536.1 - 0.00038 21.3 0.0 0.002 18.9 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EME89536.1 - 0.0034 17.4 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME89537.1 - 6.7e-13 48.6 0.1 1.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME89537.1 - 1.8e-08 33.9 0.0 4.7e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EME89537.1 - 5.7e-08 32.9 0.0 3.4e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EME89537.1 - 1.3e-07 30.5 0.0 1.9e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EME89537.1 - 0.0047 15.9 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EME89537.1 - 0.0049 15.8 0.2 0.024 13.5 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 EME89537.1 - 0.016 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EME89537.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF1501 PF07394.7 EME89541.1 - 0.23 10.2 2.6 0.36 9.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4407 PF14362.1 EME89541.1 - 0.75 8.6 8.5 1.1 8.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NACHT PF05729.7 EME89542.1 - 1e-13 51.2 0.1 2.5e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EME89542.1 - 8.2e-06 25.9 0.1 6e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EME89542.1 - 0.0001 22.4 0.2 0.00074 19.6 0.0 2.4 3 1 1 4 4 4 1 AAA domain DUF2075 PF09848.4 EME89542.1 - 0.0033 16.4 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EME89542.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 EME89542.1 - 0.04 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 EME89542.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EME89542.1 - 0.11 13.3 0.8 0.86 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.2 EME89543.1 - 1.2e-10 41.5 0.1 9.6e-05 22.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EME89543.1 - 6.2e-09 36.1 0.8 0.091 13.2 0.0 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EME89543.1 - 3.7e-08 33.3 0.3 0.00037 20.6 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EME89543.1 - 0.00015 21.4 0.7 2.3 8.2 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat GATase_7 PF13537.1 EME89543.1 - 0.00062 19.4 0.0 0.35 10.6 0.0 3.1 2 1 1 3 3 3 2 Glutamine amidotransferase domain DUF4094 PF13334.1 EME89544.1 - 0.0063 16.8 0.1 33 4.9 0.0 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF4094) YlbE PF14003.1 EME89544.1 - 0.05 13.6 3.3 0.88 9.7 0.5 2.9 1 1 1 2 2 2 0 YlbE-like protein DUF3328 PF11807.3 EME89545.1 - 1.9e-25 89.8 0.1 2.9e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sec39 PF08314.6 EME89545.1 - 0.018 13.0 0.1 0.023 12.6 0.0 1.1 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Complex1_LYR PF05347.10 EME89547.1 - 7.6e-14 51.2 0.1 1.2e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME89547.1 - 5.3e-13 48.9 0.3 8.7e-13 48.2 0.1 1.4 2 0 0 2 2 2 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 EME89548.1 - 1.7e-17 63.1 0.0 2.6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EME89548.1 - 1.5e-07 31.5 0.0 2.1e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME89548.1 - 3.7e-07 30.2 0.1 6.4e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EME89548.1 - 1.1e-05 25.1 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EME89548.1 - 3.4e-05 23.8 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EME89548.1 - 0.00087 19.1 0.1 0.0025 17.6 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EME89548.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EME89548.1 - 0.033 14.3 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EME89548.1 - 0.1 12.4 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_3 PF01494.14 EME89550.1 - 2.4e-20 72.8 0.0 4.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME89550.1 - 5.4e-12 45.2 0.0 5.6e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EME89550.1 - 2e-05 24.5 0.4 3.9e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EME89550.1 - 6.8e-05 21.5 2.0 0.011 14.2 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EME89550.1 - 0.00041 20.4 0.0 0.00079 19.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EME89550.1 - 0.00063 18.7 1.8 0.0012 17.7 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EME89550.1 - 0.001 18.9 3.1 0.0074 16.1 2.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EME89550.1 - 0.0044 15.9 2.7 0.01 14.7 1.8 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 EME89550.1 - 0.0059 15.4 0.0 0.036 12.8 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 EME89550.1 - 0.0085 14.7 3.1 0.42 9.1 0.1 2.4 3 0 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.19 EME89550.1 - 0.01 14.9 0.2 0.19 10.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EME89550.1 - 0.011 14.8 2.0 0.029 13.4 1.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EME89550.1 - 0.058 12.4 0.7 0.2 10.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Aldo_ket_red PF00248.16 EME89551.1 - 4.6e-62 209.4 0.0 5.2e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Complex1_LYR PF05347.10 EME89552.1 - 1.6e-18 66.2 1.6 1.8e-18 66.0 1.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EME89552.1 - 1.6e-15 57.0 0.7 1.9e-15 56.8 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like E1-E2_ATPase PF00122.15 EME89554.1 - 8.3e-20 70.8 0.0 3.7e-19 68.6 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EME89554.1 - 5.5e-18 66.1 0.2 4.3e-14 53.4 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EME89554.1 - 2.4e-12 47.4 0.0 9.9e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EME89554.1 - 9.2e-11 41.5 0.0 4.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EME89554.1 - 0.00068 19.2 0.2 0.0078 15.8 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_S8e PF01201.17 EME89555.1 - 3.4e-47 159.8 2.0 3.9e-47 159.6 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EME89555.1 - 0.025 14.8 0.4 0.077 13.2 0.2 1.9 1 0 0 1 1 1 0 Small acidic protein family DUF4410 PF14366.1 EME89555.1 - 0.061 13.0 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Rgp1 PF08737.5 EME89556.1 - 7.5e-99 331.6 0.0 1.5e-98 330.6 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EME89556.1 - 2e-05 24.4 0.2 0.0049 16.7 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EME89556.1 - 0.00028 20.9 0.1 0.098 12.7 0.0 3.0 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Diphthamide_syn PF01866.12 EME89557.1 - 9.1e-112 373.2 0.0 1.1e-111 372.9 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SKN1 PF03935.10 EME89558.1 - 3.8e-224 744.4 1.1 4.5e-224 744.2 0.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Inhibitor_I78 PF11720.3 EME89560.1 - 2.4e-12 46.3 0.0 3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EME89560.1 - 0.066 13.3 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Potato inhibitor I family DinI PF06183.8 EME89561.1 - 0.14 12.2 1.8 0.64 10.0 0.0 2.7 3 0 0 3 3 3 0 DinI-like family FlxA PF14282.1 EME89561.1 - 0.47 10.4 7.6 4.8 7.1 0.4 2.5 1 1 0 2 2 2 0 FlxA-like protein DUF722 PF05263.6 EME89561.1 - 1.2 9.3 8.1 0.39 10.8 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF722) SPX PF03105.14 EME89561.1 - 1.2 8.8 6.6 1.7 8.3 4.6 1.2 1 0 0 1 1 1 0 SPX domain Ribosomal_L28 PF00830.14 EME89562.1 - 4.3e-24 84.1 2.4 8.5e-24 83.1 1.6 1.5 1 0 0 1 1 1 1 Ribosomal L28 family L51_S25_CI-B8 PF05047.11 EME89563.1 - 1.4e-14 53.5 0.0 2.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GET2 PF08690.5 EME89564.1 - 0.00039 19.7 0.1 0.00062 19.1 0.0 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 Pex19 PF04614.7 EME89564.1 - 0.03 13.9 1.4 0.042 13.4 1.0 1.3 1 0 0 1 1 1 0 Pex19 protein family AKAP7_NLS PF10469.4 EME89565.1 - 1e-25 90.6 0.0 1.8e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EME89565.1 - 0.036 13.7 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily DUF3234 PF11572.3 EME89566.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) Aa_trans PF01490.13 EME89567.1 - 1.5e-52 178.5 39.4 1.7e-52 178.3 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UNC-93 PF05978.11 EME89568.1 - 3.2e-12 46.2 10.1 3.2e-12 46.2 7.0 2.6 2 1 2 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EME89568.1 - 2.8e-07 29.5 28.1 2.8e-07 29.5 19.5 2.1 1 1 2 3 3 3 1 Major Facilitator Superfamily VirB3 PF05101.8 EME89568.1 - 0.029 14.3 0.7 0.14 12.1 0.1 2.6 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Fungal_trans_2 PF11951.3 EME89569.1 - 7.4e-14 51.1 0.9 9.1e-14 50.8 0.6 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 EME89570.1 - 1.5e-24 87.2 0.0 2.1e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EME89570.1 - 0.018 13.5 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Zip PF02535.17 EME89571.1 - 3.3e-33 115.0 18.2 3.3e-33 115.0 12.6 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter HRXXH PF13933.1 EME89572.1 - 1.4e-66 224.4 0.0 1.5e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family ACC_epsilon PF13822.1 EME89572.1 - 0.028 14.7 1.2 3 8.2 1.4 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit HET PF06985.6 EME89573.1 - 1.7e-26 93.0 0.0 2.2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gly-rich_Ago1 PF12764.2 EME89575.1 - 0.064 13.8 1.5 0.097 13.3 1.1 1.4 1 0 0 1 1 1 0 Glycine-rich region of argonaut zf-met PF12874.2 EME89577.1 - 3.7e-05 23.7 0.6 3.7e-05 23.7 0.4 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EME89577.1 - 0.051 12.8 0.9 0.093 12.0 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF605 PF04652.11 EME89579.1 - 1 8.6 24.4 1.3 8.3 16.9 1.1 1 0 0 1 1 1 0 Vta1 like 2OG-FeII_Oxy PF03171.15 EME89580.1 - 3e-06 27.4 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EME89581.1 - 4.2e-19 69.2 0.0 5.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal SCA7 PF08313.7 EME89582.1 - 0.056 13.0 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 SCA7, zinc-binding domain V-ATPase_H_N PF03224.9 EME89583.1 - 1.7e-75 254.0 1.2 2.4e-75 253.5 0.9 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EME89583.1 - 2.8e-39 133.7 0.4 1.2e-38 131.6 0.0 2.2 3 0 0 3 3 3 1 V-ATPase subunit H Imm45 PF15603.1 EME89583.1 - 0.016 15.3 1.4 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 45 HEAT_2 PF13646.1 EME89583.1 - 0.028 14.7 0.1 1.2 9.5 0.0 2.9 2 1 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EME89583.1 - 0.089 12.9 0.0 0.6 10.3 0.0 2.5 1 0 0 1 1 1 0 HEAT repeat Sterol-sensing PF12349.3 EME89584.1 - 3.3e-05 23.3 0.8 3.3e-05 23.3 0.6 2.6 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Cu-oxidase_3 PF07732.10 EME89585.1 - 7.9e-44 148.1 3.9 3.1e-42 143.0 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EME89585.1 - 1.2e-37 129.2 0.0 1.2e-37 129.2 0.0 2.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EME89585.1 - 6.7e-32 109.8 2.9 1.2e-27 96.0 0.1 3.4 3 0 0 3 3 3 3 Multicopper oxidase 6PF2K PF01591.13 EME89588.1 - 2.9e-79 265.2 0.1 3.7e-79 264.9 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EME89588.1 - 2.4e-31 108.9 0.0 6e-31 107.6 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EME89588.1 - 2e-06 27.7 0.0 4.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EME89588.1 - 0.0021 17.2 0.0 0.006 15.8 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EME89588.1 - 0.0046 17.7 0.2 0.031 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain SR-25 PF10500.4 EME89589.1 - 4.9 6.5 18.0 0.18 11.2 8.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EVE PF01878.13 EME89590.1 - 4.3e-39 133.7 0.3 6.1e-39 133.2 0.2 1.2 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.14 EME89590.1 - 2.6e-09 35.6 34.3 0.015 14.8 1.7 5.9 5 0 0 5 5 5 5 AT hook motif CDC27 PF09507.5 EME89590.1 - 8.5 5.4 17.5 10 5.2 12.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_S5 PF00333.15 EME89593.1 - 3e-28 97.3 2.0 3e-28 97.3 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EME89593.1 - 2.9e-22 77.7 0.0 5.4e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Spc7_N PF15402.1 EME89594.1 - 3.3e-83 280.2 77.9 1.9e-60 204.9 19.6 4.5 1 1 3 4 4 4 4 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EME89594.1 - 1.3e-79 267.2 9.0 2.9e-79 266.0 6.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EME89594.1 - 2.8e-07 30.0 0.6 5.9e-07 29.0 0.4 1.5 1 0 0 1 1 1 1 Spc7_C2 IFT57 PF10498.4 EME89594.1 - 0.065 11.9 13.1 0.0047 15.7 4.3 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 EME89594.1 - 4.7 6.7 22.6 0.099 12.2 9.0 2.9 3 0 0 3 3 3 0 IncA protein V_ATPase_I PF01496.14 EME89594.1 - 8.4 4.1 5.7 19 2.9 3.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AA_permease_N PF08403.5 EME89595.1 - 0.065 12.5 0.3 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal Laminin_I PF06008.9 EME89596.1 - 0.0047 16.2 12.5 0.0047 16.2 8.7 2.8 3 0 0 3 3 3 1 Laminin Domain I AAA_32 PF13654.1 EME89596.1 - 0.12 10.9 9.4 0.25 9.9 6.5 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EME89596.1 - 0.48 9.4 20.5 0.082 11.9 9.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Rootletin PF15035.1 EME89596.1 - 0.5 10.3 25.5 0.028 14.4 12.2 2.3 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.2 EME89596.1 - 0.56 10.0 22.2 0.1 12.4 12.0 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF607 PF04678.8 EME89596.1 - 1 9.2 4.3 2.9 7.7 3.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF3640 PF12342.3 EME89596.1 - 1.9 8.1 3.8 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) V_ATPase_I PF01496.14 EME89596.1 - 2.3 5.9 12.4 5.4 4.7 6.3 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 EME89596.1 - 2.9 8.2 15.2 0.054 13.8 4.3 2.8 2 1 1 3 3 3 0 Snapin/Pallidin Ax_dynein_light PF10211.4 EME89596.1 - 3 7.6 20.7 1.4 8.7 9.2 2.6 2 1 0 2 2 2 0 Axonemal dynein light chain NPV_P10 PF05531.7 EME89596.1 - 5 7.4 9.5 16 5.7 1.4 3.5 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 EME89596.1 - 5.8 6.6 27.7 2.3 7.9 0.4 3.6 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EME89596.1 - 6.7 5.2 17.5 0.29 9.7 8.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA PF00004.24 EME89599.1 - 4.9e-17 62.3 0.0 8.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EME89599.1 - 0.00083 19.5 0.0 0.0059 16.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 EME89599.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 EME89599.1 - 1.1 10.0 4.0 59 4.5 1.0 3.5 2 1 0 2 2 2 0 AAA domain adh_short PF00106.20 EME89600.1 - 4.7e-31 107.9 0.4 5.2e-31 107.7 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89600.1 - 3.2e-13 49.9 0.0 3.8e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EME89600.1 - 3e-11 43.3 0.1 4e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EME89600.1 - 8e-07 28.7 0.0 9.5e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EME89600.1 - 0.00019 20.4 0.1 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.13 EME89600.1 - 0.00021 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EME89600.1 - 0.00039 19.2 0.1 0.00044 19.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.7 EME89600.1 - 0.0035 17.7 0.0 0.005 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Saccharop_dh PF03435.13 EME89600.1 - 0.0055 15.7 0.1 0.0085 15.1 0.1 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EME89600.1 - 0.0061 15.5 0.0 0.0069 15.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EME89600.1 - 0.0086 16.0 0.2 0.011 15.7 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding ELFV_dehydrog PF00208.16 EME89600.1 - 0.012 15.2 0.7 0.014 14.9 0.4 1.5 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EME89600.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EME89600.1 - 0.071 12.7 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EME89600.1 - 0.12 12.4 0.2 0.61 10.1 0.2 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Grp1_Fun34_YaaH PF01184.14 EME89603.1 - 8.6e-84 280.0 15.7 1e-83 279.7 10.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Med14 PF08638.6 EME89604.1 - 0.052 12.7 0.1 0.052 12.7 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit MED14 WSC PF01822.14 EME89605.1 - 3.6e-38 129.3 36.6 9.8e-20 70.2 11.5 2.0 2 0 0 2 2 2 2 WSC domain DUF1793 PF08760.6 EME89606.1 - 3.3e-26 92.1 1.0 6.6e-26 91.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Cornichon PF03311.9 EME89607.1 - 3.3e-54 182.4 9.3 3.7e-54 182.2 6.5 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EME89607.1 - 1.2 8.0 6.2 1.5 7.7 4.3 1.1 1 0 0 1 1 1 0 Peptidase family M50 Cytochrom_C PF00034.16 EME89608.1 - 1.7e-09 38.3 0.0 2.5e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EME89608.1 - 1.6e-07 31.3 1.8 1.2e-06 28.5 1.2 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EME89608.1 - 0.0016 17.8 0.2 0.0097 15.3 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EME89608.1 - 0.064 12.9 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C1 family CCP_MauG PF03150.9 EME89608.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase adh_short PF00106.20 EME89610.1 - 0.00044 20.1 0.1 0.00071 19.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89610.1 - 0.0026 17.5 0.0 0.044 13.5 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EME89610.1 - 0.0094 15.9 0.2 0.019 15.0 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EME89610.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EME89610.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Stc1 PF12898.2 EME89611.1 - 4.9e-16 58.5 7.9 1.1e-15 57.4 5.5 1.7 1 0 0 1 1 1 1 Stc1 domain Chorismate_bind PF00425.13 EME89614.1 - 1.2e-84 283.6 0.0 2e-84 282.9 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EME89614.1 - 5.4e-29 100.9 0.1 8.2e-26 90.6 0.0 3.2 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region CHASE3 PF05227.8 EME89614.1 - 0.23 11.1 2.2 5.9 6.5 0.0 2.9 3 0 0 3 3 3 0 CHASE3 domain Oxidored_FMN PF00724.15 EME89616.1 - 3e-67 227.0 0.0 3.9e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_63 PF03200.11 EME89617.1 - 0.0001 20.3 8.8 0.0044 14.9 0.5 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase NMT PF01233.14 EME89618.1 - 1.7e-71 239.0 0.0 2.5e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EME89618.1 - 1.6e-68 229.8 0.0 2.1e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EME89618.1 - 1.5e-07 31.3 0.0 2.4e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EME89618.1 - 0.12 12.5 0.0 0.8 9.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PALP PF00291.20 EME89619.1 - 1.5e-72 244.4 0.6 2.3e-72 243.8 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EME89619.1 - 2.2e-45 152.1 0.1 1.6e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 EME89620.1 - 3e-21 74.8 0.0 3.9e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Med16 PF11635.3 EME89621.1 - 2.6e-97 326.6 0.0 3.7e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 SIR2 PF02146.12 EME89622.1 - 2.7e-23 82.6 0.0 1.7e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 Sir2 family Peptidase_C97 PF05903.9 EME89623.1 - 2.1e-29 102.2 0.0 2.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EME89623.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Spt5_N PF11942.3 EME89623.1 - 3.4 8.3 11.5 5.2 7.7 7.9 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal YcfA PF07927.7 EME89624.1 - 4.5e-06 26.4 0.0 9.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 YcfA-like protein ATG11 PF10377.4 EME89624.1 - 0.097 12.5 0.2 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 11 adh_short PF00106.20 EME89625.1 - 6.8e-21 74.8 0.0 9.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EME89625.1 - 3e-14 53.3 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EME89625.1 - 7.9e-08 31.7 0.0 9.7e-07 28.2 0.0 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.11 EME89625.1 - 0.015 14.7 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 EME89625.1 - 0.06 12.5 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.1 EME89625.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 NADH(P)-binding Glyco_hydro_42C PF08533.5 EME89625.1 - 0.12 11.9 0.1 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain MmgE_PrpD PF03972.9 EME89627.1 - 8.7e-149 495.4 0.0 1.1e-148 495.1 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family GSH_synth_ATP PF03917.12 EME89628.1 - 2.6e-60 203.9 0.0 8.6e-59 198.9 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EME89628.1 - 1.4e-29 102.2 0.0 3.5e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Ferric_reduct PF01794.14 EME89630.1 - 5.7e-19 68.4 6.5 5.7e-19 68.4 4.5 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EME89630.1 - 6.7e-12 45.5 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EME89630.1 - 4.5e-11 42.5 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EME89630.1 - 0.0055 17.2 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain adh_short PF00106.20 EME89631.1 - 0.026 14.4 0.3 2.3 8.0 0.0 2.1 1 1 1 2 2 2 0 short chain dehydrogenase DUF3453 PF11935.3 EME89635.1 - 2e-68 230.3 0.0 3.4e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) NAP PF00956.13 EME89635.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Coiled-coil_56 PF09813.4 EME89636.1 - 3.7e-05 23.6 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 bZIP_1 PF00170.16 EME89638.1 - 4e-08 33.1 9.1 5.9e-08 32.5 6.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EME89638.1 - 7.3e-08 32.1 10.2 1e-07 31.6 7.1 1.2 1 0 0 1 1 1 1 Basic region leucine zipper PspA_IM30 PF04012.7 EME89638.1 - 0.0041 16.5 5.8 0.0055 16.0 4.1 1.1 1 0 0 1 1 1 1 PspA/IM30 family DivIC PF04977.10 EME89638.1 - 0.0058 16.0 2.8 0.0091 15.4 2.0 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_Maf PF03131.12 EME89638.1 - 0.026 14.8 8.8 0.04 14.2 6.1 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor CENP-Q PF13094.1 EME89638.1 - 0.036 14.1 3.0 0.05 13.6 2.0 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 EME89638.1 - 0.042 14.1 0.4 0.091 13.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF4407 PF14362.1 EME89638.1 - 0.38 9.6 4.8 0.51 9.2 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.1 EME89638.1 - 1.4 9.3 5.8 2.2 8.8 4.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ABC_tran_2 PF12848.2 EME89638.1 - 3.9 7.3 8.6 5.4 6.9 5.9 1.2 1 0 0 1 1 1 0 ABC transporter IncA PF04156.9 EME89639.1 - 5.1e-05 22.9 9.7 5.1e-05 22.9 6.7 5.1 4 1 3 7 7 7 1 IncA protein MscS_porin PF12795.2 EME89639.1 - 0.067 12.4 66.6 0.039 13.2 5.4 4.3 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EME89639.1 - 1.8 7.6 29.8 0.81 8.8 1.4 3.9 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EME89639.1 - 6 6.6 33.4 1.1 9.1 1.0 5.3 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DASH_Hsk3 PF08227.6 EME89641.1 - 4.4e-19 68.3 2.4 5.9e-19 67.9 1.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF3138 PF11336.3 EME89641.1 - 0.039 12.1 0.2 0.04 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FlxA PF14282.1 EME89641.1 - 0.039 13.9 0.7 0.051 13.5 0.5 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF591 PF04569.9 EME89642.1 - 0.13 12.3 0.2 0.17 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function SRF-TF PF00319.13 EME89643.1 - 1.1e-23 82.1 0.2 1.5e-23 81.7 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 EME89643.1 - 0.057 12.7 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.9 EME89643.1 - 0.085 10.8 0.1 0.12 10.3 0.1 1.3 1 0 0 1 1 1 0 CDC45-like protein AsmA_2 PF13502.1 EME89644.1 - 0.031 13.6 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 AsmA-like C-terminal region Terminase_4 PF05119.7 EME89644.1 - 0.051 13.7 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Phage terminase, small subunit Terminase_4 PF05119.7 EME89645.1 - 0.035 14.2 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage terminase, small subunit Spt5-NGN PF03439.8 EME89648.1 - 4.5e-20 71.1 0.0 8.8e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EME89648.1 - 1e-16 61.3 11.8 1e-16 61.3 8.2 3.6 2 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EME89648.1 - 2.4e-08 34.4 41.1 5.9e-07 29.9 25.9 3.3 2 1 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EME89648.1 - 0.00023 20.7 23.4 0.11 12.2 0.8 5.9 6 0 0 6 6 6 3 KOW motif COX5B PF01215.14 EME89648.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb AAA_22 PF13401.1 EME89649.1 - 4.1e-07 30.2 0.0 9.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EME89649.1 - 7.1e-07 29.0 0.1 3e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DUF2370 PF10176.4 EME89649.1 - 0.008 15.5 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) AAA_10 PF12846.2 EME89649.1 - 0.019 14.4 0.1 0.043 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 EME89649.1 - 0.02 13.8 0.4 0.29 10.0 0.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 EME89649.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EME89649.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EME89649.1 - 0.096 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EME89649.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EME89649.1 - 0.13 13.1 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EME89649.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EME89649.1 - 0.18 11.4 0.0 0.47 10.1 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EME89649.1 - 0.2 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 EME89649.1 - 0.25 11.1 0.1 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 KaiC PF06745.8 EME89649.1 - 0.28 10.2 0.0 0.68 9.0 0.0 1.5 2 0 0 2 2 2 0 KaiC Peptidase_M24 PF00557.19 EME89650.1 - 3e-42 144.5 0.0 5.1e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EME89650.1 - 1.7e-06 28.5 0.0 2.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain ADH_zinc_N PF00107.21 EME89651.1 - 2e-21 75.8 0.6 3e-21 75.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EME89651.1 - 5.1e-07 30.6 0.1 9.7e-07 29.7 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 EME89651.1 - 0.002 18.0 0.2 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EME89651.1 - 0.0041 16.5 0.1 0.0053 16.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.16 EME89651.1 - 0.047 13.2 1.2 0.063 12.8 0.8 1.3 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase KR PF08659.5 EME89651.1 - 0.069 12.8 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 EME89651.1 - 0.075 12.8 1.5 0.13 12.0 1.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyoxalase_3 PF13468.1 EME89656.1 - 7.5e-23 81.3 0.0 1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain CAP160 PF07918.6 EME89656.1 - 0.042 13.4 0.2 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 CAP160 repeat IBR PF01485.16 EME89657.1 - 1.6e-09 37.4 49.3 3.2e-05 23.6 7.7 5.9 4 2 0 4 4 4 2 IBR domain Bromodomain PF00439.20 EME89657.1 - 2.4e-07 30.5 0.0 5.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Nucleoplasmin PF03066.10 EME89657.1 - 2.6 7.5 7.9 4.4 6.8 5.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin MTBP_N PF14918.1 EME89657.1 - 3 7.1 5.9 35 3.6 2.6 2.2 2 0 0 2 2 2 0 MDM2-binding F-box-like PF12937.2 EME89661.1 - 0.0034 17.0 0.0 0.0088 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EME89661.1 - 0.0056 16.2 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 F-box domain Topoisom_bac PF01131.15 EME89662.1 - 8e-91 304.8 0.0 5.6e-86 288.8 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EME89662.1 - 4.4e-13 49.0 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Cupin_2 PF07883.6 EME89662.1 - 2.5e-09 36.5 1.2 4.6e-09 35.6 0.9 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EME89662.1 - 2.2e-07 30.4 0.3 7.5e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 EME89662.1 - 0.01 15.4 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.2 EME89662.1 - 0.093 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Cupin API5 PF05918.6 EME89662.1 - 3.8 5.9 10.3 5.7 5.3 7.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Sel1 PF08238.7 EME89663.1 - 5.9e-43 144.3 28.4 7.6e-08 32.7 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_16 PF13432.1 EME89663.1 - 9.6e-06 26.1 4.5 0.044 14.4 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EME89663.1 - 0.033 14.5 8.1 2.4 8.5 0.0 5.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EME89663.1 - 0.17 12.4 9.2 38 5.0 0.8 5.8 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME89663.1 - 1.3 9.8 18.9 11 6.9 0.1 6.6 6 2 2 8 8 8 0 Tetratricopeptide repeat YscJ_FliF_C PF08345.6 EME89664.1 - 3 7.7 6.9 2.4 8.0 4.2 1.3 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal Rep_fac_C PF08542.6 EME89665.1 - 1.8e-24 85.4 0.0 3.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EME89665.1 - 4e-12 46.1 0.0 8.2e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EME89665.1 - 4.4e-06 26.9 0.2 1.1e-05 25.6 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EME89665.1 - 0.00023 21.1 1.8 0.051 13.5 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EME89665.1 - 0.00026 21.1 2.0 0.0011 19.1 0.5 2.5 1 1 2 3 3 3 1 AAA domain ABC_tran PF00005.22 EME89665.1 - 0.003 17.8 0.1 0.0077 16.5 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EME89665.1 - 0.006 16.0 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EME89665.1 - 0.015 15.3 0.2 0.48 10.4 0.2 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain SNF2_N PF00176.18 EME89665.1 - 0.016 14.0 0.1 0.02 13.6 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EME89665.1 - 0.018 14.4 0.1 0.51 9.7 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EME89665.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EME89665.1 - 0.025 14.4 0.1 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EME89665.1 - 0.057 13.1 0.4 0.14 11.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EME89665.1 - 0.074 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EME89665.1 - 0.1 12.1 0.4 0.24 10.9 0.3 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EME89665.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase DUF1689 PF07954.6 EME89666.1 - 0.023 14.5 1.1 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Ndc1_Nup PF09531.5 EME89666.1 - 1.4 7.2 6.3 2.2 6.6 4.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 4HBT_3 PF13622.1 EME89667.1 - 1.7e-29 103.3 0.0 2.1e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily adh_short PF00106.20 EME89668.1 - 1e-17 64.5 0.0 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EME89668.1 - 2.3e-05 24.1 0.1 3.4e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EME89668.1 - 0.00014 21.7 0.0 0.00046 20.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Oxidored_nitro PF00148.14 EME89668.1 - 0.00053 18.7 0.0 0.00077 18.1 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Epimerase PF01370.16 EME89668.1 - 0.0081 15.6 0.2 0.017 14.5 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EME89668.1 - 0.041 12.5 0.4 0.053 12.2 0.3 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 EME89668.1 - 0.046 13.5 0.3 0.092 12.5 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.10 EME89668.1 - 0.16 10.8 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_16 PF13191.1 EME89669.1 - 6.1e-06 26.3 0.8 0.00022 21.2 0.6 2.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EME89669.1 - 8.6e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EME89669.1 - 0.0019 17.6 0.0 0.0061 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EME89669.1 - 0.0078 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EME89669.1 - 0.045 13.2 0.0 0.29 10.5 0.0 2.3 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EME89669.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) OTT_1508_deam PF14441.1 EME89671.1 - 3.7e-13 49.4 0.0 2.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 OTT_1508-like deaminase A_deaminase PF00962.17 EME89672.1 - 3.5e-45 154.3 0.0 5.4e-45 153.7 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_3 PF07969.6 EME89672.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family WD40 PF00400.27 EME89674.1 - 7.7e-32 108.0 9.8 1.3e-09 37.5 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EME89674.1 - 0.00027 19.2 0.1 0.00084 17.5 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EME89674.1 - 0.0055 16.4 0.1 1 9.0 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EME89674.1 - 0.032 13.1 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) CorA PF01544.13 EME89675.1 - 1.4e-27 96.4 6.0 5.2e-23 81.4 2.5 2.7 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein GTP_EFTU PF00009.22 EME89677.1 - 6.3e-39 133.3 0.1 1.1e-38 132.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EME89677.1 - 7.3e-32 109.0 0.0 1.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EME89677.1 - 8.4e-30 102.7 0.0 2e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EME89677.1 - 5.8e-24 83.7 0.0 9.1e-23 79.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EME89677.1 - 2.2e-13 50.1 0.2 6.1e-13 48.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EME89677.1 - 0.031 14.1 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) MMR_HSR1 PF01926.18 EME89677.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Laminin_I PF06008.9 EME89678.1 - 0.0016 17.8 1.1 0.0024 17.2 0.8 1.3 1 0 0 1 1 1 1 Laminin Domain I CBP4 PF07960.6 EME89678.1 - 0.021 14.4 3.8 0.038 13.5 2.6 1.4 1 0 0 1 1 1 0 CBP4 DUF4110 PF13422.1 EME89678.1 - 0.31 10.9 5.0 1 9.2 2.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) MTBP_C PF14920.1 EME89678.1 - 0.88 9.0 5.3 0.4 10.1 1.8 1.8 1 1 0 1 1 1 0 MDM2-binding TRP PF06011.7 EME89680.1 - 2e-73 247.4 11.1 6.8e-40 136.9 5.5 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EME89680.1 - 7.6e-30 103.7 0.1 1.3e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 ML-like domain Abhydrolase_6 PF12697.2 EME89681.1 - 6e-22 78.6 0.0 7e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME89681.1 - 1.4e-09 37.8 0.0 1.9e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME89681.1 - 2.2e-07 30.6 0.0 0.0058 16.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EME89681.1 - 7.8e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Cutinase PF01083.17 EME89681.1 - 0.00046 19.9 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Cutinase DUF900 PF05990.7 EME89681.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EME89681.1 - 0.061 12.9 0.2 0.3 10.6 0.0 2.0 2 1 0 2 2 2 0 Serine hydrolase Fringe PF02434.11 EME89682.1 - 2.6e-07 30.1 1.6 1e-05 24.9 0.8 2.4 2 1 0 2 2 2 1 Fringe-like PAN_1 PF00024.21 EME89682.1 - 0.00082 19.0 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 PAN domain Glyco_transf_34 PF05637.7 EME89682.1 - 0.0091 15.5 0.5 0.0091 15.5 0.3 1.7 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family PAN_4 PF14295.1 EME89682.1 - 0.015 14.9 0.5 0.041 13.5 0.3 1.7 1 0 0 1 1 1 0 PAN domain MFS_1 PF07690.11 EME89683.1 - 2.3e-25 89.0 46.9 3.6e-18 65.4 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2909 PF11137.3 EME89683.1 - 0.011 15.5 1.3 0.087 12.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF1228 PF06779.9 EME89683.1 - 0.18 11.8 15.7 0.085 12.8 0.4 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) SGL PF08450.7 EME89688.1 - 4.7e-10 39.2 0.0 0.00078 18.8 0.0 4.8 2 1 4 6 6 6 4 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EME89688.1 - 0.0035 17.1 4.7 1.1 9.5 0.1 4.7 6 0 0 6 6 6 1 Two component regulator propeller Glu_cyclase_2 PF05096.7 EME89688.1 - 0.0089 15.0 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Glutamine cyclotransferase PQQ_2 PF13360.1 EME89688.1 - 0.036 13.5 0.0 0.41 10.0 0.0 2.4 1 1 0 1 1 1 0 PQQ-like domain Abhydrolase_6 PF12697.2 EME89689.1 - 3e-25 89.4 0.0 4.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME89689.1 - 3.6e-18 65.9 0.0 5.9e-18 65.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EME89689.1 - 8.4e-13 48.2 0.0 1.8e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EME89689.1 - 3.5e-05 23.1 0.0 0.0091 15.2 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EME89689.1 - 3.7e-05 23.0 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EME89689.1 - 0.00048 19.6 0.0 0.088 12.2 0.0 2.4 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EME89689.1 - 0.0032 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EME89689.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 EME89689.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Vac_ImportDeg PF09783.4 EME89693.1 - 2.3e-06 27.2 0.1 0.0002 20.9 0.0 2.9 2 1 0 2 2 2 1 Vacuolar import and degradation protein Ribosomal_L7Ae PF01248.21 EME89694.1 - 8.1e-28 95.7 1.0 1.1e-27 95.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Chalcone PF02431.10 EME89695.1 - 2.8e-53 180.2 0.0 3.2e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Chalcone-flavanone isomerase MFS_1 PF07690.11 EME89697.1 - 8.9e-08 31.2 7.1 8.9e-08 31.2 4.9 3.5 1 1 1 3 3 3 3 Major Facilitator Superfamily DUF443 PF04276.7 EME89697.1 - 0.037 13.4 1.6 1.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Glyco_hydro_31 PF01055.21 EME89698.1 - 7.3e-82 275.5 0.0 9.5e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EME89698.1 - 9.5e-13 47.8 0.0 2.5e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like UvdE PF03851.9 EME89699.1 - 8.1e-114 379.3 0.0 1e-113 378.9 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE FliC_SP PF12613.3 EME89699.1 - 4.1 7.6 4.7 8 6.7 3.3 1.4 1 0 0 1 1 1 0 Flagellin structural protein Abhydrolase_3 PF07859.8 EME89700.1 - 2.4e-10 40.3 0.0 5e-10 39.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Coleoptericin PF06286.6 EME89701.1 - 0.043 13.7 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Coleoptericin RNase_PH PF01138.16 EME89702.1 - 2.9e-20 72.9 0.0 6.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 TrmE_N PF10396.4 EME89702.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus RNase_PH_C PF03725.10 EME89702.1 - 0.045 13.6 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Fungal_trans_2 PF11951.3 EME89703.1 - 0.059 11.9 0.0 0.085 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SnoaL PF07366.7 EME89705.1 - 0.00024 20.7 0.2 0.00052 19.5 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EME89705.1 - 0.0052 17.1 0.1 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain AAA PF00004.24 EME89706.1 - 6.5e-43 146.0 0.0 1.1e-41 142.1 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Cyclin PF08613.6 EME89706.1 - 1.5e-12 48.1 0.0 4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Cyclin AAA_16 PF13191.1 EME89706.1 - 2.1e-06 27.8 0.1 1e-05 25.6 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EME89706.1 - 3.7e-06 26.4 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EME89706.1 - 1.5e-05 24.9 0.0 6.4e-05 22.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 EME89706.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 EME89706.1 - 0.00045 20.3 0.0 0.0037 17.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EME89706.1 - 0.0012 18.5 0.0 0.0042 16.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EME89706.1 - 0.0028 17.5 0.0 0.0088 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EME89706.1 - 0.0039 16.6 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EME89706.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EME89706.1 - 0.011 15.4 0.1 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EME89706.1 - 0.012 15.4 0.7 0.034 14.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EME89706.1 - 0.015 15.5 0.0 0.07 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EME89706.1 - 0.026 14.5 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.8 EME89706.1 - 0.034 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Cyclin_N PF00134.18 EME89706.1 - 0.042 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain AAA_17 PF13207.1 EME89706.1 - 0.05 14.4 0.0 0.05 14.4 0.0 3.4 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EME89706.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EME89706.1 - 0.069 12.1 0.1 0.18 10.8 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EME89706.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EME89706.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EME89706.1 - 0.14 11.7 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EME89706.1 - 0.22 10.7 0.0 0.42 9.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.9 EME89706.1 - 1.4 7.7 0.0 2.4 7.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.27 EME89707.1 - 1.4e-06 27.9 0.2 0.21 11.5 0.0 4.3 5 1 0 5 5 5 2 WD domain, G-beta repeat Lactonase PF10282.4 EME89707.1 - 0.0017 17.5 0.0 0.0033 16.5 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Thioredoxin PF00085.15 EME89708.1 - 7.6e-20 70.5 0.1 9.1e-20 70.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EME89708.1 - 2.1e-05 24.1 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EME89708.1 - 0.0003 20.8 0.1 0.027 14.6 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EME89708.1 - 0.0003 20.9 0.2 0.0083 16.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_5 PF13743.1 EME89708.1 - 0.0038 16.7 0.4 1.2 8.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.5 EME89708.1 - 0.0044 16.5 0.1 0.0076 15.7 0.1 1.4 1 1 0 1 1 1 1 Redoxin TPR_2 PF07719.12 EME89709.1 - 3.3e-06 26.5 13.4 0.015 15.1 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EME89709.1 - 5.6e-05 22.9 9.9 0.0034 17.2 1.2 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EME89709.1 - 9.3e-05 22.0 10.9 0.009 15.6 0.1 4.9 4 1 1 5 5 5 1 TPR repeat TPR_7 PF13176.1 EME89709.1 - 0.0013 18.3 7.5 12 5.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EME89709.1 - 0.005 17.4 0.9 0.005 17.4 0.6 6.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EME89709.1 - 0.0075 16.5 9.0 0.035 14.4 0.2 4.6 6 1 0 6 6 5 1 Tetratricopeptide repeat UCR_hinge PF02320.11 EME89709.1 - 0.013 15.4 0.3 0.026 14.4 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein TPR_17 PF13431.1 EME89709.1 - 0.013 15.6 0.9 24 5.4 0.1 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EME89709.1 - 0.023 15.1 11.4 4.8 7.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EME89709.1 - 0.029 13.9 7.6 2.6 7.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EME89709.1 - 0.06 13.1 0.0 6.8 6.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME89709.1 - 1.2 9.9 16.6 48 4.9 0.5 7.9 8 2 2 10 10 8 0 Tetratricopeptide repeat BSD PF03909.12 EME89710.1 - 2.2e-14 52.9 4.5 4.1e-14 52.0 3.1 1.5 1 0 0 1 1 1 1 BSD domain TLE_N PF03920.10 EME89710.1 - 0.038 13.8 0.2 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain Pectate_lyase PF03211.8 EME89711.1 - 1.6e-62 210.7 1.0 1.9e-62 210.4 0.7 1.0 1 0 0 1 1 1 1 Pectate lyase Peptidase_S58 PF03576.9 EME89712.1 - 1.4e-08 34.3 0.3 1.9e-08 33.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase family S58 zf-Apc11 PF12861.2 EME89713.1 - 1.2e-41 140.3 8.1 1.7e-41 139.9 5.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EME89713.1 - 1.7e-29 101.6 8.9 2.4e-29 101.2 6.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EME89713.1 - 2e-08 33.9 16.3 3.7e-08 33.0 11.3 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EME89713.1 - 0.0013 18.3 12.7 0.0029 17.2 8.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EME89713.1 - 0.0018 17.9 14.0 0.044 13.4 10.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EME89713.1 - 0.0022 17.6 15.9 0.03 14.0 11.4 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EME89713.1 - 0.0058 16.6 14.5 0.036 14.0 10.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EME89713.1 - 0.026 14.1 4.4 0.026 14.1 3.1 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_S14 PF00253.16 EME89713.1 - 0.099 12.0 4.0 1.8 7.9 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e FANCL_C PF11793.3 EME89713.1 - 0.1 12.6 13.7 0.64 10.0 9.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 EME89713.1 - 0.45 10.3 9.0 1 9.1 6.2 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.6 EME89713.1 - 4.4 7.3 14.7 19 5.3 10.2 2.0 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 EME89713.1 - 9 6.3 13.6 2.6 8.0 6.4 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain Rhodanese PF00581.15 EME89714.1 - 3.8e-22 78.7 0.0 1.1e-13 51.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DIOX_N PF14226.1 EME89717.1 - 5.6e-14 52.6 0.0 8.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EME89717.1 - 5e-12 45.9 0.0 9.6e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ald_Xan_dh_C2 PF02738.13 EME89717.1 - 0.015 13.6 0.0 0.022 13.0 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Dehydratase_hem PF13816.1 EME89718.1 - 1.3e-75 254.2 0.0 1.5e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DAGK_cat PF00781.19 EME89720.1 - 8.9e-25 86.6 0.1 2e-24 85.4 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.3 EME89720.1 - 0.041 12.4 0.4 0.28 9.7 0.1 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ribosomal_L10 PF00466.15 EME89721.1 - 0.006 16.4 0.1 0.02 14.7 0.0 1.8 3 0 0 3 3 3 1 Ribosomal protein L10 COG2 PF06148.6 EME89721.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Glycos_transf_3 PF00591.16 EME89722.1 - 5.8e-61 206.0 0.0 9e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EME89722.1 - 9.2e-11 41.1 1.2 2.1e-10 40.0 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Cyclin_C PF02984.14 EME89722.1 - 0.32 10.9 1.9 3.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain Kelch_6 PF13964.1 EME89724.1 - 3.7e-05 23.6 0.3 0.031 14.4 0.0 3.8 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 EME89724.1 - 0.00052 19.7 0.5 10 5.9 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EME89724.1 - 0.0043 16.9 0.0 14 5.7 0.0 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EME89724.1 - 0.01 15.3 1.1 2.1 7.9 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 EME89724.1 - 0.033 13.9 0.0 25 4.8 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 EME89724.1 - 0.068 13.3 1.8 4.9 7.4 0.1 4.1 3 1 0 3 3 3 0 Galactose oxidase, central domain MFS_1 PF07690.11 EME89725.1 - 1.5e-25 89.6 81.3 6.4e-25 87.6 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EME89726.1 - 5.2e-66 223.1 0.2 7.3e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EME89726.1 - 7.5e-06 25.0 1.4 0.063 12.1 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EME89726.1 - 9.4e-06 25.9 0.1 0.00024 21.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EME89726.1 - 0.00011 21.2 0.3 0.052 12.4 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EME89726.1 - 0.00036 19.1 0.1 0.0007 18.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EME89726.1 - 0.0038 17.2 0.1 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME89726.1 - 0.005 16.9 0.1 0.045 13.8 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EME89726.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CamS PF07537.6 EME89726.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor DIT1_PvcA PF05141.7 EME89728.1 - 7.2e-90 301.0 0.0 9.2e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EME89728.1 - 2.2e-25 89.7 0.0 4.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nefa_Nip30_N PF10187.4 EME89729.1 - 7.3e-27 93.5 8.9 7.3e-27 93.5 6.2 2.4 1 1 2 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF883 PF05957.8 EME89729.1 - 0.028 14.7 2.1 0.028 14.7 1.4 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4545 PF15078.1 EME89729.1 - 0.98 8.2 6.7 1.2 7.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) Fungal_trans PF04082.13 EME89730.1 - 1.2e-23 83.3 0.5 1.8e-23 82.7 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EME89730.1 - 1.1e-09 38.0 8.7 2.1e-09 37.1 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 EME89731.1 - 2e-21 75.8 0.0 3.9e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EME89731.1 - 3.7e-15 56.5 0.0 8.1e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EME89731.1 - 4.4e-07 29.8 0.8 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EME89731.1 - 7.5e-07 28.3 0.1 9.1e-05 21.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EME89731.1 - 1.8e-05 24.5 0.0 4.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EME89731.1 - 0.00022 20.4 0.1 0.00071 18.7 0.0 1.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 EME89731.1 - 0.00068 19.5 0.1 0.081 12.7 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EME89731.1 - 0.0017 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EME89731.1 - 0.0065 14.9 0.3 0.013 14.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EME89731.1 - 0.007 16.7 1.4 1.5 9.2 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EME89731.1 - 0.037 14.1 0.8 5.2 7.1 0.3 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EME89731.1 - 0.05 13.8 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EME89731.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF148 PF02520.12 EME89732.1 - 0.041 13.6 0.1 0.041 13.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 Esterase PF00756.15 EME89733.1 - 2.2e-11 43.6 5.7 4e-11 42.8 1.3 2.4 1 1 0 2 2 2 1 Putative esterase HMGL-like PF00682.14 EME89734.1 - 1.6e-37 129.4 0.0 4.1e-28 98.6 0.0 2.1 2 0 0 2 2 2 2 HMGL-like Tom37_C PF11801.3 EME89735.1 - 2.2e-27 96.0 0.0 4.1e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain GST_C_2 PF13410.1 EME89735.1 - 1.2e-07 31.4 0.1 7.6e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EME89735.1 - 3.6e-07 30.3 0.0 8.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 EME89735.1 - 6.2e-05 23.4 0.0 0.00025 21.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EME89735.1 - 0.0047 16.8 0.0 0.0097 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.19 EME89736.1 - 1.5e-98 330.3 18.4 1.7e-98 330.1 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME89736.1 - 1.8e-16 59.8 36.4 7.1e-14 51.2 8.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EME89736.1 - 0.0008 19.3 5.0 0.042 13.8 0.7 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) ORMDL PF04061.9 EME89736.1 - 2 7.9 6.7 7.3 6.1 1.3 2.7 1 1 1 2 2 2 0 ORMDL family BLOC1_2 PF10046.4 EME89737.1 - 0.0072 16.4 0.6 0.016 15.3 0.4 1.6 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.1 EME89737.1 - 0.0089 15.2 1.2 0.011 14.9 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DUF2365 PF10157.4 EME89737.1 - 0.04 13.8 0.7 0.048 13.5 0.5 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DASH_Dad2 PF08654.5 EME89737.1 - 0.05 13.6 0.7 2.6 8.1 0.1 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad2 DELLA PF12041.3 EME89737.1 - 0.055 13.1 0.7 0.13 11.9 0.2 1.8 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal Kinetochor_Ybp2 PF08568.5 EME89737.1 - 0.15 10.2 0.4 0.17 10.1 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Y_phosphatase3C PF13348.1 EME89737.1 - 0.27 11.3 1.8 4.2 7.5 0.0 3.0 4 0 0 4 4 4 0 Tyrosine phosphatase family C-terminal region FliJ PF02050.11 EME89737.1 - 0.75 9.8 11.5 1.4 8.9 4.0 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4570 PF15134.1 EME89737.1 - 2.7 7.8 6.4 0.62 9.9 2.0 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4570) Fasciclin PF02469.17 EME89738.1 - 3.7e-45 153.0 0.0 5.1e-24 84.7 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain FAD_binding_7 PF03441.9 EME89739.1 - 1.9e-57 194.6 0.1 2.6e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EME89739.1 - 6.9e-22 77.9 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase PIG-U PF06728.8 EME89740.1 - 2.7e-108 362.2 24.3 3.2e-108 361.9 16.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EME89741.1 - 5.1e-114 380.2 0.3 5.1e-114 380.2 0.2 2.2 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EME89741.1 - 2.5e-10 40.3 0.0 1e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NAD_binding_11 PF14833.1 EME89742.1 - 1e-18 67.5 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EME89742.1 - 1.4e-17 64.0 2.1 1.4e-15 57.5 1.5 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EME89742.1 - 0.04 14.3 1.6 0.28 11.6 1.1 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Beta-lactamase PF00144.19 EME89743.1 - 7.3e-43 146.8 0.0 1e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EME89743.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) MFS_1 PF07690.11 EME89744.1 - 6.2e-38 130.4 8.6 6.2e-38 130.4 5.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EME89744.1 - 2.3e-13 49.5 9.4 5e-13 48.4 0.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EME89744.1 - 3.2e-13 48.8 0.0 1.6e-05 23.4 0.9 4.0 1 1 3 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 EME89744.1 - 0.0024 17.6 0.1 0.022 14.5 0.0 2.7 3 0 0 3 3 3 1 MFS_1 like family LacY_symp PF01306.14 EME89744.1 - 0.0092 14.5 1.3 0.48 8.9 0.0 2.4 2 1 0 2 2 2 2 LacY proton/sugar symporter TRI12 PF06609.8 EME89744.1 - 0.0099 14.1 0.3 0.016 13.4 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EME89744.1 - 0.76 8.1 23.8 0.023 13.1 3.2 3.9 2 2 0 2 2 2 0 Vacuole effluxer Atg22 like Glyco_hydro_3 PF00933.16 EME89745.1 - 3.3e-91 305.3 0.0 4.6e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EME89745.1 - 2.1e-52 177.8 0.2 1.5e-51 175.1 0.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EME89745.1 - 1.9e-21 75.7 0.1 3.8e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Transaldolase PF00923.14 EME89747.1 - 3.4e-34 118.2 0.0 4.7e-34 117.8 0.0 1.3 1 1 0 1 1 1 1 Transaldolase Sugar_tr PF00083.19 EME89748.1 - 1e-86 291.3 22.3 1.3e-86 291.0 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EME89748.1 - 1.5e-21 76.5 56.2 5.6e-18 64.7 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IBR PF01485.16 EME89749.1 - 8.9e-07 28.6 5.9 8.9e-07 28.6 4.1 3.5 2 2 0 3 3 3 2 IBR domain KH_1 PF00013.24 EME89751.1 - 4e-41 138.4 15.8 4.7e-14 51.7 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EME89751.1 - 1.2e-32 110.9 10.4 1.1e-10 40.9 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EME89751.1 - 1.7e-13 49.9 7.4 0.00024 20.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EME89751.1 - 6.2e-08 32.1 7.0 0.063 12.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EME89751.1 - 1.5e-05 24.6 5.9 0.015 15.0 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EME89751.1 - 0.025 14.0 0.1 3.5 7.1 0.0 3.1 3 0 0 3 3 3 0 dUTPase GRP PF07172.6 EME89751.1 - 0.027 14.9 36.7 0.11 12.9 4.3 3.3 3 0 0 3 3 3 0 Glycine rich protein family AAA_17 PF13207.1 EME89752.1 - 5.1e-06 27.2 0.1 7.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EME89752.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EME89752.1 - 0.00033 20.9 0.4 0.0013 19.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 EME89752.1 - 0.0031 17.0 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EME89752.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EME89752.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain CoaE PF01121.15 EME89752.1 - 0.14 11.5 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase DUF1741 PF08427.5 EME89753.1 - 5.6e-66 222.3 0.1 1.2e-65 221.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) AlaDh_PNT_N PF05222.10 EME89753.1 - 0.021 14.8 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain MscL PF01741.13 EME89753.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL DUF726 PF05277.7 EME89754.1 - 2.9e-116 388.1 1.9 2.9e-116 388.1 1.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EME89754.1 - 1.3e-05 25.4 3.6 2.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EME89754.1 - 4e-05 23.6 0.1 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME89754.1 - 0.003 17.3 0.4 0.0075 16.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME89754.1 - 0.0076 15.8 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorosome_CsmC PF11098.3 EME89754.1 - 0.16 11.7 4.2 0.41 10.3 2.1 2.2 2 0 0 2 2 2 0 Chlorosome envelope protein C Dynactin PF12455.3 EME89755.1 - 9.3e-78 260.8 13.2 9.3e-78 260.8 9.2 4.1 5 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.20 EME89755.1 - 1.5e-23 82.2 0.4 2.4e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Strep_SA_rep PF06696.6 EME89755.1 - 0.73 9.6 9.7 0.52 10.1 0.2 4.0 3 1 1 4 4 4 0 Streptococcal surface antigen repeat SPO22 PF08631.5 EME89756.1 - 7.9e-21 74.3 10.0 3.1e-14 52.7 0.2 4.8 4 2 2 6 6 6 2 Meiosis protein SPO22/ZIP4 like YbjQ_1 PF01906.12 EME89758.1 - 0.51 10.7 3.7 0.59 10.5 0.1 2.8 2 1 0 2 2 2 0 Putative heavy-metal-binding Img2 PF05046.9 EME89758.1 - 3 8.1 6.5 5.1 7.3 0.3 3.5 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Aldo_ket_red PF00248.16 EME89759.1 - 2.7e-54 183.9 0.0 3.1e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Macoilin PF09726.4 EME89760.1 - 0.21 9.8 4.4 0.25 9.5 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Acyl-CoA_dh_1 PF00441.19 EME89761.1 - 1.5e-38 132.2 1.0 2.4e-38 131.6 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EME89761.1 - 7.7e-21 73.3 0.3 1.3e-20 72.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EME89761.1 - 3.5e-19 68.3 0.3 7.8e-19 67.2 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EME89761.1 - 4e-16 59.5 0.1 1.6e-15 57.6 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EME89761.1 - 3.1e-06 27.4 0.1 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosamine_iso PF01182.15 EME89762.1 - 4.3e-58 196.3 0.0 5e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TPR_17 PF13431.1 EME89763.1 - 2.2e-05 24.2 1.0 0.25 11.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EME89763.1 - 8.3e-05 22.1 8.1 0.061 12.9 0.0 3.5 4 0 0 4 4 4 2 TPR repeat DUF848 PF05852.6 EME89763.1 - 0.018 14.8 0.3 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_12 PF13424.1 EME89763.1 - 0.028 14.3 8.7 1.4 8.9 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EME89763.1 - 0.028 15.0 0.7 0.028 15.0 0.5 5.0 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EME89763.1 - 0.13 12.6 5.9 1.3 9.4 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EME89763.1 - 2 9.2 8.7 2.8 8.8 0.1 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat TMEM51 PF15345.1 EME89764.1 - 0.025 14.2 0.1 0.038 13.6 0.0 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 COX14 PF14880.1 EME89764.1 - 0.14 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly SLAC1 PF03595.12 EME89765.1 - 8.4e-101 336.9 46.5 9.5e-101 336.7 32.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF21 PF01595.15 EME89765.1 - 0.0097 15.2 0.8 0.0097 15.2 0.5 3.2 2 1 0 3 3 3 1 Domain of unknown function DUF21 PH_9 PF15410.1 EME89766.1 - 0.053 13.6 0.0 0.77 9.9 0.0 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Amidase PF01425.16 EME89768.1 - 7.8e-73 245.8 0.0 1.1e-72 245.3 0.0 1.2 1 0 0 1 1 1 1 Amidase Clr5 PF14420.1 EME89769.1 - 0.012 15.4 2.1 0.02 14.7 0.0 2.5 3 0 0 3 3 3 0 Clr5 domain p450 PF00067.17 EME89770.1 - 4.2e-10 38.7 0.0 3.1e-09 35.8 0.0 2.3 3 1 0 3 3 3 1 Cytochrome P450 4HBT PF03061.17 EME89771.1 - 1.2e-11 44.5 0.2 2.1e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EME89771.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EME89771.1 - 0.0069 16.3 0.0 0.0087 16.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) YiiD_Cterm PF09500.5 EME89771.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) DUF1674 PF07896.7 EME89772.1 - 3.9e-17 62.1 3.4 9.4e-17 60.9 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) V-SNARE PF05008.10 EME89773.1 - 3.6e-21 75.1 5.3 3.6e-21 75.1 3.7 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EME89773.1 - 3.2e-17 62.3 8.5 4e-17 62.0 3.9 2.5 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EME89773.1 - 0.00098 18.7 2.2 0.0016 18.1 0.2 2.2 2 2 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 EME89773.1 - 0.0049 14.9 2.1 0.025 12.6 0.1 2.1 2 0 0 2 2 2 1 Fusion glycoprotein F0 Spectrin PF00435.16 EME89773.1 - 0.021 15.0 4.1 0.061 13.6 1.2 2.4 1 1 1 2 2 2 0 Spectrin repeat Synaptobrevin PF00957.16 EME89773.1 - 0.06 12.9 3.5 0.18 11.4 1.5 2.4 1 1 1 2 2 2 0 Synaptobrevin YvbH_ext PF11724.3 EME89773.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 YvbH-like oligomerisation region DUF912 PF06024.7 EME89773.1 - 0.32 11.0 0.1 0.32 11.0 0.1 1.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OppC_N PF12911.2 EME89773.1 - 0.58 9.5 3.7 1.1 8.7 2.6 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C NAD_binding_8 PF13450.1 EME89774.1 - 1.7e-14 53.5 0.0 4.2e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EME89774.1 - 9.4e-05 22.5 0.0 0.00027 21.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EME89774.1 - 0.0003 19.8 0.0 0.00073 18.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EME89774.1 - 0.00038 19.6 0.1 0.0063 15.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EME89774.1 - 0.00043 19.2 0.0 0.00073 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EME89774.1 - 0.00061 18.9 0.0 0.00099 18.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EME89774.1 - 0.0035 17.2 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EME89774.1 - 0.0038 17.0 0.1 0.014 15.2 0.0 2.0 3 0 0 3 3 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EME89774.1 - 0.0043 17.4 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EME89774.1 - 0.01 14.3 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EME89774.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.14 EME89774.1 - 0.047 11.8 0.0 0.072 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Proteasome PF00227.21 EME89776.1 - 6e-56 188.7 0.0 1.2e-31 109.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EME89776.1 - 1.9e-11 43.0 0.3 4.2e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.2 EME89777.1 - 9.9e-10 38.3 5.5 2.7e-09 36.9 1.3 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EME89777.1 - 3.7e-05 23.4 3.4 0.00037 20.2 0.7 2.2 2 0 0 2 2 2 1 Ring finger domain ABC2_membrane_2 PF12679.2 EME89777.1 - 0.00073 18.4 0.4 0.00095 18.0 0.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein zf-MIZ PF02891.15 EME89777.1 - 0.0084 15.6 2.4 0.018 14.5 1.7 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF1206 PF06724.6 EME89777.1 - 0.0094 15.6 0.4 0.0094 15.6 0.3 2.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1206) zf-GRF PF06839.7 EME89777.1 - 0.21 11.5 3.1 0.52 10.2 2.2 1.6 1 1 0 1 1 1 0 GRF zinc finger PHD PF00628.24 EME89777.1 - 1.2 8.9 7.0 0.18 11.5 2.1 1.7 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.1 EME89777.1 - 7.8 6.1 10.4 1.9 8.1 4.6 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain APH PF01636.18 EME89778.1 - 4.8e-18 65.7 0.1 7.4e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EME89778.1 - 9.3e-07 28.6 0.0 1.3e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase zf-CCCH PF00642.19 EME89779.1 - 6.1e-08 32.1 2.6 9.8e-08 31.5 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NUFIP1 PF10453.4 EME89779.1 - 3.3e-07 29.7 0.4 9.4e-07 28.2 0.3 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_2 PF14608.1 EME89779.1 - 0.23 11.5 5.0 0.59 10.2 3.4 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RNA_pol_Rbc25 PF08292.7 EME89780.1 - 3e-26 92.0 0.1 3.9e-26 91.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EME89780.1 - 4.4e-14 52.3 0.2 6.5e-14 51.8 0.2 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Abhydrolase_6 PF12697.2 EME89782.1 - 8.3e-23 81.4 0.2 4.1e-22 79.1 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EME89782.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EME89782.1 - 0.0003 20.4 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EME89782.1 - 0.0026 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF4123 PF13503.1 EME89782.1 - 0.11 12.5 0.1 0.38 10.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) UAF_Rrn10 PF05234.6 EME89784.1 - 0.0001 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 ESCRT-II PF05871.7 EME89785.1 - 5.6e-47 159.1 0.0 2.5e-46 157.0 0.0 1.8 1 1 1 2 2 2 1 ESCRT-II complex subunit DUF2427 PF10348.4 EME89786.1 - 4.1e-06 26.2 8.6 4.1e-06 26.2 5.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 EME89786.1 - 1.3e-05 25.0 12.6 1.3e-05 25.0 8.8 1.8 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.1 EME89786.1 - 0.57 10.1 12.1 2.1 8.3 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF3951 PF13131.1 EME89786.1 - 4.3 7.1 6.7 0.52 10.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) ERG4_ERG24 PF01222.12 EME89787.1 - 2.3e-158 527.2 5.0 2.9e-158 526.9 3.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EME89787.1 - 0.00012 21.4 0.9 0.00021 20.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Pkinase PF00069.20 EME89788.1 - 5.1e-60 202.8 0.0 1e-59 201.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89788.1 - 1.1e-31 109.8 0.0 6e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EME89788.1 - 0.012 14.4 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EME89788.1 - 0.44 10.1 2.8 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Pkinase PF00069.20 EME89789.1 - 1.2e-61 208.1 0.0 1.6e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89789.1 - 5.7e-29 100.9 0.0 8.1e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME89789.1 - 0.021 14.5 0.0 0.17 11.5 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Calcipressin PF04847.7 EME89790.1 - 2.1e-44 151.2 0.7 2.8e-44 150.8 0.5 1.2 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EME89790.1 - 0.034 13.8 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Phage_cap_P2 PF05125.7 EME89790.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family LIM PF00412.17 EME89791.1 - 5.6e-26 90.3 30.8 3.3e-10 39.8 2.8 3.7 4 0 0 4 4 4 3 LIM domain Paired_CXXCH_1 PF09699.5 EME89791.1 - 0.085 12.3 0.1 0.085 12.3 0.1 4.3 3 1 1 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) CAP PF00188.21 EME89791.1 - 0.085 13.3 0.6 0.18 12.3 0.4 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF2321 PF10083.4 EME89791.1 - 0.88 9.0 6.7 0.88 9.0 2.5 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Solute_trans_a PF03619.11 EME89792.1 - 1.3e-41 142.7 0.3 1.7e-41 142.3 0.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CK_II_beta PF01214.13 EME89793.1 - 1.8e-77 258.9 0.0 8.8e-77 256.7 0.0 1.8 1 1 0 1 1 1 1 Casein kinase II regulatory subunit CENP-B_dimeris PF09026.5 EME89793.1 - 0.016 15.4 2.7 0.016 15.4 1.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Spt5_N PF11942.3 EME89793.1 - 2.6 8.7 25.8 0.092 13.3 6.4 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SpoIIE PF07228.7 EME89794.1 - 3.4e-13 49.7 0.0 1.6e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EME89794.1 - 8.1e-09 35.2 0.0 0.0026 17.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EME89794.1 - 0.00082 18.8 0.9 0.0053 16.1 0.6 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PH PF00169.24 EME89795.1 - 5.1e-09 36.2 0.6 2e-08 34.3 0.4 2.1 1 1 0 1 1 1 1 PH domain GRAM PF02893.15 EME89795.1 - 0.013 14.9 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 GRAM domain PH_11 PF15413.1 EME89795.1 - 0.23 11.7 2.8 5.2 7.3 2.0 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain Dynactin_p62 PF05502.8 EME89796.1 - 3e-121 405.5 0.6 3.9e-121 405.1 0.4 1.2 1 0 0 1 1 1 1 Dynactin p62 family Pkinase PF00069.20 EME89797.1 - 1.7e-39 135.5 0.0 2.6e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EME89797.1 - 5e-30 104.4 0.0 7.7e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EME89797.1 - 0.0014 18.3 0.0 0.67 9.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EME89797.1 - 0.12 11.3 0.2 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 Kinase-like PIP5K PF01504.13 EME89798.1 - 5e-57 192.9 1.5 1.1e-56 191.8 1.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EME89798.1 - 3e-25 88.8 0.0 4.6e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EME89798.1 - 3.6e-14 52.3 3.7 3.6e-14 52.3 2.6 2.3 2 1 0 2 2 2 1 FYVE zinc finger DZR PF12773.2 EME89798.1 - 0.024 14.4 5.2 0.083 12.7 1.7 2.7 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EME89798.1 - 0.27 10.9 8.7 0.098 12.4 2.2 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 EME89798.1 - 2.7 7.6 4.9 8.4 6.1 0.9 3.1 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EME89798.1 - 4.5 6.9 11.1 9.3 6.0 0.1 3.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain ABC_tran PF00005.22 EME89799.1 - 1.2e-26 93.6 0.0 2e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME89799.1 - 0.002 18.1 0.0 0.083 12.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EME89799.1 - 0.0023 17.1 0.1 0.004 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_4 PF12730.2 EME89799.1 - 0.0027 16.8 14.8 0.0027 16.8 10.2 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein SbcCD_C PF13558.1 EME89799.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EME89799.1 - 0.03 14.4 0.3 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 EME89799.1 - 0.071 12.4 0.2 0.2 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EME89799.1 - 0.11 11.2 1.1 0.23 10.2 0.2 1.8 2 0 0 2 2 2 0 ArgK protein IIGP PF05049.8 EME89799.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF1639 PF07797.9 EME89799.1 - 0.21 11.0 0.2 1 8.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1639) ABC2_membrane PF01061.19 EME89800.1 - 3.5e-34 117.8 22.8 3.5e-34 117.8 15.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EME89800.1 - 1.4e-27 96.6 0.0 2.3e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EME89800.1 - 1.3e-07 31.9 0.0 1.5e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_2 PF12679.2 EME89800.1 - 4.2e-05 22.5 11.4 4.2e-05 22.5 7.9 2.6 3 0 0 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 EME89800.1 - 9.4e-05 21.5 20.7 9.4e-05 21.5 14.4 2.5 3 0 0 3 3 2 1 ABC-2 family transporter protein hEGF PF12661.2 EME89800.1 - 0.0012 18.7 24.2 0.029 14.4 1.1 4.4 4 0 0 4 4 4 2 Human growth factor-like EGF AAA_25 PF13481.1 EME89800.1 - 0.0024 17.2 0.1 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EME89800.1 - 0.016 14.6 0.1 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EME89800.1 - 0.024 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EME89800.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EME89800.1 - 0.057 14.2 0.0 0.16 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EME89800.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EME89800.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EME89800.1 - 0.098 11.6 0.0 4.6 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EME89800.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EME89800.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EME89800.1 - 0.2 10.2 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 EME89800.1 - 0.27 10.6 0.1 0.49 9.8 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EME89801.1 - 3e-36 124.7 0.0 8.7e-17 61.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EME89801.1 - 4.3e-15 56.4 0.4 0.054 13.4 0.0 4.7 3 2 1 4 4 4 4 AAA domain RLI PF04068.10 EME89801.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 EME89801.1 - 3.1e-11 42.9 1.7 0.0063 15.7 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EME89801.1 - 1.6e-07 31.5 0.0 0.0068 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EME89801.1 - 6.4e-07 30.2 0.1 0.084 13.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EME89801.1 - 1.8e-06 27.2 0.5 0.78 8.7 0.0 4.4 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 EME89801.1 - 2.6e-06 27.6 0.1 0.0098 16.1 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EME89801.1 - 1.6e-05 24.1 1.1 0.16 11.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EME89801.1 - 3.4e-05 24.1 0.0 0.23 11.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EME89801.1 - 5.3e-05 22.6 0.1 0.22 11.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.10 EME89801.1 - 6.1e-05 21.9 0.0 0.039 12.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EME89801.1 - 7.6e-05 22.8 0.4 0.11 12.6 0.0 3.2 4 0 0 4 4 2 1 RNA helicase AAA_33 PF13671.1 EME89801.1 - 8.8e-05 22.4 0.0 0.038 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 EME89801.1 - 0.00012 21.4 3.1 0.00012 21.4 2.2 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain SRP54 PF00448.17 EME89801.1 - 0.00014 21.3 1.3 0.045 13.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 EME89801.1 - 0.00022 20.9 1.0 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EME89801.1 - 0.00035 20.2 2.0 0.063 12.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EME89801.1 - 0.00048 19.7 0.2 0.0059 16.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EME89801.1 - 0.00049 20.4 0.0 0.046 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 EME89801.1 - 0.00051 19.8 11.8 0.001 18.8 8.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 EME89801.1 - 0.00058 19.3 0.0 0.97 8.8 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E AAA_16 PF13191.1 EME89801.1 - 0.00074 19.5 0.0 0.79 9.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EME89801.1 - 0.0012 18.3 0.0 0.46 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EME89801.1 - 0.0028 18.1 0.6 0.56 10.7 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein Thymidylate_kin PF02223.12 EME89801.1 - 0.0032 16.8 0.1 2.9 7.2 0.0 2.4 2 0 0 2 2 2 2 Thymidylate kinase AAA_5 PF07728.9 EME89801.1 - 0.0082 15.8 0.2 0.52 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EME89801.1 - 0.0083 15.7 0.1 0.41 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 EME89801.1 - 0.011 15.5 11.9 0.031 14.1 2.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 EME89801.1 - 0.012 15.3 1.9 0.012 15.3 1.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.1 EME89801.1 - 0.02 14.7 0.7 5.5 6.9 0.0 3.0 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EME89801.1 - 0.038 13.5 1.2 0.42 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EME89801.1 - 0.038 12.8 0.1 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 EME89801.1 - 0.049 13.5 0.1 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 EME89801.1 - 0.051 14.3 0.1 0.051 14.3 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_13 PF13166.1 EME89801.1 - 0.068 11.6 0.9 0.13 10.6 0.0 1.9 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EME89801.1 - 0.075 11.9 0.0 7.8 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.1 EME89801.1 - 0.085 12.7 0.0 8.4 6.3 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EME89801.1 - 0.096 12.3 1.8 6 6.5 0.1 2.7 2 0 0 2 2 2 0 NTPase KaiC PF06745.8 EME89801.1 - 0.13 11.4 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 KaiC ArgK PF03308.11 EME89801.1 - 0.15 10.8 0.1 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 ArgK protein PduV-EutP PF10662.4 EME89801.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_7 PF12838.2 EME89801.1 - 0.49 10.8 13.4 0.043 14.2 1.3 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EME89801.1 - 0.79 9.7 9.8 0.46 10.5 1.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EME89801.1 - 0.86 9.6 12.8 0.48 10.4 1.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 EME89801.1 - 1.6 9.0 14.7 0.057 13.6 1.7 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ABC_tran PF00005.22 EME89802.1 - 1.4e-46 158.2 1.0 1.4e-22 80.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EME89802.1 - 8.2e-15 55.5 0.5 0.0074 16.2 0.2 4.4 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EME89802.1 - 4.8e-09 35.7 0.5 0.082 12.1 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EME89802.1 - 2.2e-08 34.9 0.1 0.0064 17.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EME89802.1 - 3.1e-06 27.6 8.1 0.017 15.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 EME89802.1 - 8.7e-06 26.0 1.2 0.074 13.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 EME89802.1 - 8.9e-06 26.2 0.1 0.01 16.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 EME89802.1 - 1e-05 24.7 0.6 0.13 11.3 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 EME89802.1 - 1e-05 24.9 0.7 0.084 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EME89802.1 - 3.9e-05 23.7 0.0 0.42 10.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 EME89802.1 - 4.8e-05 22.5 0.1 0.022 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME89802.1 - 0.00011 22.2 3.1 0.01 15.8 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 EME89802.1 - 0.00013 21.9 0.0 0.039 13.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 EME89802.1 - 0.00036 20.2 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EME89802.1 - 0.00048 20.0 0.1 1.2 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EME89802.1 - 0.00052 19.7 0.2 0.62 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EME89802.1 - 0.0011 19.2 0.1 1.7 8.8 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran_2 PF12848.2 EME89802.1 - 0.0013 18.4 3.7 0.0013 18.4 2.5 3.8 6 0 0 6 6 4 1 ABC transporter AAA_10 PF12846.2 EME89802.1 - 0.0034 16.8 0.5 1.5 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EME89802.1 - 0.0036 17.2 0.2 4.8 7.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 EME89802.1 - 0.0042 16.9 0.5 8.9 6.3 0.3 4.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EME89802.1 - 0.0049 17.0 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 EME89802.1 - 0.005 15.6 3.0 0.94 8.2 0.1 2.8 3 0 0 3 3 3 2 ArgK protein AAA_25 PF13481.1 EME89802.1 - 0.0055 16.1 0.0 2.7 7.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EME89802.1 - 0.0065 15.5 0.1 0.96 8.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EME89802.1 - 0.01 15.5 0.2 2.5 7.7 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.1 EME89802.1 - 0.011 15.7 6.5 0.16 11.9 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.1 EME89802.1 - 0.028 13.9 0.1 9.4 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EME89802.1 - 0.042 13.3 0.7 7.1 6.0 0.4 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EME89802.1 - 0.044 13.6 2.9 0.45 10.3 0.0 2.8 3 0 0 3 3 2 0 Dynamin family ATP-synt_ab PF00006.20 EME89802.1 - 0.044 13.2 0.0 0.6 9.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EME89802.1 - 0.05 12.4 0.0 2.6 6.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EME89802.1 - 0.06 13.0 0.2 6.5 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EME89802.1 - 0.1 12.0 1.2 3.2 7.1 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EME89802.1 - 0.14 11.6 0.9 5.3 6.5 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EME89802.1 - 0.45 10.0 1.9 32 3.9 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EME89802.1 - 4.7 5.5 8.5 8.4 4.7 0.4 3.6 3 1 0 3 3 3 0 AAA domain ABC_membrane PF00664.18 EME89803.1 - 8.5e-75 251.6 25.0 7.3e-39 133.8 6.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EME89803.1 - 2.8e-56 189.5 0.0 6.6e-28 97.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EME89803.1 - 8e-18 64.4 1.3 2e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EME89803.1 - 8.4e-12 45.3 0.0 5.4e-05 23.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EME89803.1 - 1.7e-10 41.3 0.2 0.034 14.0 0.0 4.0 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 EME89803.1 - 1.2e-09 37.2 3.7 0.00084 18.0 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EME89803.1 - 2.4e-09 36.5 0.6 0.0025 17.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EME89803.1 - 5.9e-09 36.7 0.1 0.0052 17.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EME89803.1 - 7.8e-08 32.0 5.8 0.096 12.0 0.1 4.4 4 0 0 4 4 4 2 AAA-like domain AAA_25 PF13481.1 EME89803.1 - 2.7e-07 30.2 1.2 0.02 14.3 0.6 3.7 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EME89803.1 - 2.8e-07 29.8 0.0 0.01 15.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EME89803.1 - 1.5e-06 28.3 0.2 0.084 12.8 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EME89803.1 - 9e-06 25.3 0.0 0.0083 15.6 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EME89803.1 - 2e-05 24.9 0.8 0.4 11.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EME89803.1 - 5.3e-05 22.8 0.6 0.0097 15.6 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_23 PF13476.1 EME89803.1 - 9.3e-05 22.8 1.2 0.16 12.3 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EME89803.1 - 0.00032 20.3 0.0 0.045 13.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EME89803.1 - 0.00047 19.9 0.1 0.17 11.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EME89803.1 - 0.0021 17.9 0.2 2.2 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EME89803.1 - 0.0024 17.7 0.3 31 4.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain DUF3987 PF13148.1 EME89803.1 - 0.0029 16.2 0.0 1.2 7.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_13 PF13166.1 EME89803.1 - 0.0042 15.6 2.8 0.54 8.6 0.0 3.3 4 0 0 4 4 4 1 AAA domain Sigma54_activ_2 PF14532.1 EME89803.1 - 0.0065 16.5 0.0 7.7 6.5 0.0 3.2 3 0 0 3 3 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.18 EME89803.1 - 0.0095 15.8 1.9 1.8 8.5 0.1 3.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase NACHT PF05729.7 EME89803.1 - 0.011 15.4 0.1 2 8.0 0.0 3.1 2 1 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 EME89803.1 - 0.016 15.1 0.2 2.4 8.1 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 EME89803.1 - 0.018 14.6 0.3 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EME89803.1 - 0.03 14.4 0.2 12 6.1 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Thymidylate_kin PF02223.12 EME89803.1 - 0.032 13.6 0.0 2 7.7 0.0 3.0 3 0 0 3 3 2 0 Thymidylate kinase CPT PF07931.7 EME89803.1 - 0.055 13.1 0.2 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EME89803.1 - 0.057 13.1 1.0 8.2 6.1 0.1 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EME89803.1 - 0.081 12.0 0.0 5.5 6.0 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin PRK PF00485.13 EME89803.1 - 0.11 12.0 0.1 5.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CoaE PF01121.15 EME89803.1 - 0.14 11.5 1.0 1.9 7.8 0.2 2.6 2 0 0 2 2 2 0 Dephospho-CoA kinase NB-ARC PF00931.17 EME89803.1 - 0.15 10.8 0.1 14 4.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 EME89803.1 - 0.23 11.2 7.7 0.46 10.2 0.1 3.5 5 0 0 5 5 4 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EME89803.1 - 0.23 10.4 0.9 22 3.9 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain KaiC PF06745.8 EME89803.1 - 0.35 9.9 7.2 21 4.1 0.0 3.9 4 0 0 4 4 4 0 KaiC AAA_28 PF13521.1 EME89803.1 - 0.6 10.0 2.7 2.6 8.0 0.2 3.0 3 0 0 3 3 2 0 AAA domain CbiA PF01656.18 EME89803.1 - 0.7 9.2 3.1 7.4 5.9 0.0 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zot PF05707.7 EME89803.1 - 3.2 7.1 6.0 1.8 8.0 0.0 3.2 4 0 0 4 4 4 0 Zonular occludens toxin (Zot)